title: Orbital abscesses caused by Fusobacterium necrophorum.
abstract: The authors describe 2 cases of young men who presented with pansinusitis and Fusobacterium necrophorum orbital abscesses. The first patient had a complicated clinical course including epidural abscess formation and meningitis. He underwent surgical evacuation of the abscesses and sinus drainage and required long-term broad spectrum antibiotic therapy with full recovery. The second patient had a clinical course complicated by F. necrophorum septicemia. He required surgical evacuation of the abscess, sinus drainage, and long-term broad-spectrum antibiotic therapy and has remained asymptomatic since. F. necrophorum may be emerging as an increasingly prevalent pathogen in orbital abscesses and can portend a more aggressive clinical course where early surgical intervention may be prudent.
authors.affiliation: Department of Ophthalmic Plastic and Reconstructive Surgery, Jules Stein Eye Institute, University of California, Los Angeles, California 90095, USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Ralli
authors.forename: Mehryar
authors.initials: M
authors.lastname: Taban
authors.forename: Ronald
authors.initials: R
authors.lastname: Mancini
authors.forename: Robert A
authors.initials: RA
authors.lastname: Goldberg
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005674:Fusobacterium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005675:Fusobacterium necrophorum / Q000302:isolation & purification*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D000077731:Meropenem; D008795:Metronidazole / Q000627:therapeutic use; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D013845:Thienamycins / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D008795:Metronidazole; D014640:Vancomycin; D000077731:Meropenem