Evaluation of antibodies against different Epstein-Barr virus nuclear antigen 1 peptides in diagnosis of nasopharyngeal carcinoma.
Epstein-Barr virus nuclear antigen 1 (EBNA1) is a protein expressed consistently in nasopharyngeal carcinoma (NPC). Although antibody levels against three different EBNA1 peptides were all high in NPC patients, the correlation between any two biomarkers was low. Therefore, the selection of distinct EBNA1 peptides could render different results in serological detection for individuals with NPC.
Gu
Ai-Di
AD
State Key Laboratory of Oncology in Southern China, Guangzhou, China.
Mo
Hao-Yuan
HY
Bei
Jin-Xin
JX
Xie
Yan-Bo
YB
Chen
Li-Zhen
LZ
Feng
Qi-Sheng
QS
Kang
Tiebang
T
Zeng
Yi-Xin
YX
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D019309:Epstein-Barr Virus Nuclear Antigens; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000821:virology; D010455:Peptides; D012680:Sensitivity and Specificity; D055815:Young Adult
D000914:Antibodies, Viral; D019309:Epstein-Barr Virus Nuclear Antigens; D010455:Peptides; C417029:EBV-encoded nuclear antigen 1