title: Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin.
abstract: Widespread use of mobile phones has increased the human exposure to electromagnetic fields (EMFs). It is required to investigate the effect of EMFs on the biological systems. In this paper the effect of mobile phone RF (910MHz and 940 MHz) on structure and function of HbA was investigated. Oxygen affinity was measured by sodium dithionite with UV-vis spectrophotometer. Structural changes were studied by circular dichroism and fluorescence spectroscopy. The results indicated that mobile phone EMFs altered oxygen affinity and tertiary structure of HbA. Furthermore, the decrease of oxygen affinity of HbA corresponded to the EMFs intensity and time of exposure.
authors.affiliation: Institute of Biochemistry and Biophysics, University of Tehran, Iran.
authors.forename: Seyed Jafar
authors.initials: SJ
authors.lastname: Mousavy
authors.forename: Gholam Hossein
authors.initials: GH
authors.lastname: Riazi
authors.forename: Mahmood
authors.initials: M
authors.lastname: Kamarei
authors.forename: Hadi
authors.initials: H
authors.lastname: Aliakbarian
authors.forename: Naghmeh
authors.initials: N
authors.lastname: Sattarahmady
authors.forename: Ahmad
authors.initials: A
authors.lastname: Sharifizadeh
authors.forename: Shahrokh
authors.initials: S
authors.lastname: Safarian
authors.forename: Faizan
authors.initials: F
authors.lastname: Ahmad
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Moosavi-Movahedi
mesh_terms: D000817:Anilino Naphthalenesulfonates / Q000737:chemistry; D002021:Buffers; D040421:Cell Phone; D002942:Circular Dichroism; D005453:Fluorescence; D006454:Hemoglobins / Q000737:chemistry* / Q000378:metabolism* / Q000528:radiation effects; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000378:metabolism; D011489:Protein Denaturation; D017510:Protein Folding; D020836:Protein Structure, Quaternary; D011846:Radio Waves; D013696:Temperature; D013997:Time Factors
chemical_list: D000817:Anilino Naphthalenesulfonates; D002021:Buffers; D006454:Hemoglobins; C027132:1-anilino-8-naphthalenesulfonate; D010100:Oxygen