Different medicaments in fetus maturation--corticosteroid usage.
OBJECTIVE
The object of work is pointing out the significance of improvement highly risk pregnancies by applying artificial fetal lungs maturation in relation to expected outcomes without adequate therapy.


METHODS
We analyzed fetal lung maturation by using lecithin and sphingomyelin ratio in embryo fluid received by foam test. We examined successfulness of artificial fetal lungs maturation by applying corticosteroids to the embryo in a group of patients with serious form of growth retardation (group A), then to the mother (group B) and by inducing partial mild form of asphyxia with oxytocin infusion (group C).


RESULTS
The success of the method is shown by the success of finished pregnancies. We followed the difference between expected and actual term of delivery.


CONCLUSIONS
Artificial fetal lungs maturation by applying fetal corticosteroids efficiently increases the creation of lecithin and sphingomyelin and enables life of neonate even in period up to 30th week of gestation.
Gojnic
M
M
Institute of Gynecology and Obstetrics, University of Belgrade, Belgrade, Serbia. gojagoya@EUnet.yu
Brankovic
M
M
Pervulov
M
M
Dugalic
S
S
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D001034:Apgar Score; D001835:Body Weight; D005260:Female; D005317:Fetal Growth Retardation / Q000188:drug therapy; D005325:Fetal Organ Maturity / Q000187:drug effects*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D054709:Lecithins / Q000032:analysis; D008168:Lung / Q000196:embryology*; D010120:Oxytocics / Q000627:therapeutic use; D010121:Oxytocin / Q000627:therapeutic use; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D013109:Sphingomyelins / Q000032:analysis
D000305:Adrenal Cortex Hormones; D054709:Lecithins; D010120:Oxytocics; D013109:Sphingomyelins; D010121:Oxytocin