title: [Medical therapy in peripheral arterial occlusive disease].
abstract: Atherosclerotic peripheral arterial disease (PAD) is often asymptomatic. If symptomatic, patients present intermittent claudication, ischemic rest pain or tissue necrosis. The prevalence of PAD increases with age and affects about 2% of patients at 60 years. Patients with PAD have an increased risk of coronary or cerebro-vascular events. Measure of the ankle-brachial index (ABI) allows early detection of asymptomatic patients, and allows early preventive interventions, in order to reduce their cardio-vascular risk. The most important interventions are smoking cessation, normalisation of blood pressure and lipid levels, and introduction of an antiplatelet agent, such as aspirin 75 to 160 mg/d.
authors.affiliation: Service d'angiologie et de médecine, Hôpital cantonal, 1700 Fribourg. periardd@h-fr.ch
authors.forename: Daniel
authors.initials: D
authors.lastname: Périard
authors.forename: Daniel
authors.initials: D
authors.lastname: Hayoz
authors.forename: Lucia
authors.initials: L
authors.lastname: Mazzolai
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors