[Transjugular intrahepatic portosystemic shunt for refractory ascites: results in 50 patients].
In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.
Kanazawa
Hidenori
H
Department of Gastroenterology, Nippon Medical School, Japan.
Narahara
Yoshiyuki
Y
Fukuda
Takeshi
T
Kondo
Chisa
C
Harimoto
Hirotomo
H
Matsushita
Yoko
Y
Kidokoro
Hideko
H
Katakura
Tamaki
T
Atsukawa
Masanori
M
Taki
Yasuhiko
Y
Kimura
Yu
Y
Osada
Yuji
Y
Nakatsuka
Katsuhisa
K
Sakamoto
Choitsu
C
D001201:Ascites / Q000401:mortality / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011446:Prospective Studies; D011788:Quality of Life; D015996:Survival Rate; D016896:Treatment Outcome