title: Relationship between adiponectin, inflammatory markers and obesity in type 2 diabetic and non-diabetic Trinidadians.
abstract: OBJECTIVE
  To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians.
  
  
  METHODS
  It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels, lipid profiles and glucose were measured in fasting blood samples.
  
  
  RESULTS
  Adiponectin levels were significantly lower (P = 0.003) in diabetics (n = 60) than non diabetics (n = 73). No correlation between adiponectin and inflammatory markers was found. Adiponectin levels were negatively correlated with BMI adjusting for age and diabetic status, and gender (beta = -0.200, P = 0.020; beta = -0.235, P = 0.004).
  
  
  CONCLUSIONS
  No correlation exists between adiponectin and inflammatory markers. Adiponectin levels are lower in type 2 diabetic Trinidadians than in non-diabetics and decreases with increasing adiposity, using BMI as the marker.
authors.affiliation: University of the West Indies, Champs Fleurs, Trinidad and Tobago. shiv25@gmail.com
authors.forename: Shivananda
authors.initials: S
authors.lastname: Nayak
authors.forename: Stephanie Quan
authors.initials: SQ
authors.lastname: Soon
authors.forename: Ryan
authors.initials: R
authors.lastname: Kunjal
authors.forename: Ria
authors.initials: R
authors.lastname: Ramadoo
authors.forename: Okera
authors.initials: O
authors.lastname: Baptiste
authors.forename: Josann
authors.initials: J
authors.lastname: Persad
authors.forename: Vasant
authors.initials: V
authors.lastname: Temull
authors.forename: Leon
authors.initials: L
authors.lastname: Diptee
authors.forename: Sophia
authors.initials: S
authors.lastname: Balgobin
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000886:Anthropometry; D015415:Biomarkers / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D014300:Trinidad and Tobago; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D055815:Young Adult
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein