A false positive F-FDG PET/CT scan caused by breast silicone injection.
We present here the case of a 40-year-old woman with a greater than 10 year prior history of bilateral breast silicone injection and saline bag implantation. Bilateral palpable breast nodules were observed, but the ultrasound scan was suboptimal and the magnetic resonance imaging showed no gadolinium-enhanced tumor. The (18)F-FDG PET/CT scan showed a hypermetabolic nodule in the left breast with a 30% increase of (18)F-FDG uptake on the delayed imaging, and this mimicked breast cancer. She underwent a left partial mastectomy and the pathology demonstrated a siliconoma.
Chen
Chao-Jung
CJ
Department of Nuclear Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.
Lee
Bi-Fang
BF
Yao
Wei-Jen
WJ
Wu
Pei-Shan
PS
Chen
Wen-Chung
WC
Peng
Shu-Lin
SL
Chiu
Nan-Tsing
NT
D000328:Adult; D018427:Breast Implants / Q000009:adverse effects; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D015745:Granuloma, Foreign-Body / Q000175:diagnosis*; D006801:Humans; D007267:Injections; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D012828:Silicones; D019788:Fluorodeoxyglucose F18