title: Obesity and complicated diverticular disease: is there an association?
abstract: OBJECTIVE
  Obesity is becoming a growing health concern in the general population. Multiple studies have linked diverticular disease to obesity. Furthermore, recent research has shown fat to be a critical element in the regulation of immunity and the inflammatory response. In this study, we sought to determine if body mass index (BMI) is associated with a higher incidence of complicated diverticulitis.
  
  
  METHODS
  A retrospective review of patients hospitalized with complicated diverticulitis between 1997 and 2006 was conducted. Medical, surgical and CT (Computed Tomography) guided interventions were evaluated in reference to age, gender, BMI and length of hospital stay (LOS).
  
  
  RESULTS
  Charts of 104 controls and 614 patients hospitalized with complicated diverticulitis were reviewed based on specified inclusion and exclusion criteria. There was no significant difference between groups by either gender (P = 0.066) or BMI (P = 0.648). There was a significant difference in age and LOS between three of the analyzed groups. No correlation was noted between BMI and LOS in any of the groups.
  
  
  CONCLUSIONS
  There has been increasing interest in obesity and its ramifications in all areas of medicine, including diverticular disease. Numerous studies have shown a strong correlation between acute diverticulitis and obesity, particularly in the young population. This study was undertaken to identify a possible link between complicated diverticulitis and obesity. Anecdotal reports and a few studies have found a parallel association. However, in this retrospective study, no correlation was found between BMI and the incidence of complicated diverticulitis.
authors.affiliation: Department of Gastroenterology, Division of Medicine, Providence Hospital and Medical Center, Southfield, MI 48075, USA. serge.sorser@providence-stjohnhealth.org
authors.forename: Serge A
authors.initials: SA
authors.lastname: Sorser
authors.forename: Tal B
authors.initials: TB
authors.lastname: Hazan
authors.forename: Michael
authors.initials: M
authors.lastname: Piper
authors.forename: Luis C
authors.initials: LC
authors.lastname: Maas
mesh_terms: D000368:Aged; D015992:Body Mass Index; D016022:Case-Control Studies; D004238:Diverticulitis / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed