title: An update on osteoporosis.
abstract: Osteoporosis is a skeletal disease that currently affects more than 25 million men and women in the United States. This silent affliction presents asymptomatically as the compromised bone composition in the body goes unrealized and may ultimately lead to fractures. Without treatment or preventative measures, the risks of morbidity and mortality are increased. Complications arising from osteoporosis are often a result of disease-related fractures, which can lead to decreased efficiency of activities of daily life, disabling pain, loss of independent living, and, in some instances, death. Early diagnosis is crucial, and treatment or prevention is highly recommended for the most optimal outcome. Individualized therapy is necessary due to the multitude of therapeutic options. As the population of Americans older than 65 years is expected to double by the year 2050, osteoporosis prevention and treatment will be vital to effective patient care.
authors.affiliation: Department of Pharmaceutical Services, University of Chicago Medical Center, Chicago, IL, USA.
authors.forename: Beth
authors.initials: B
authors.lastname: Nochowitz
authors.forename: Sherry
authors.initials: S
authors.lastname: Siegert
authors.forename: Mitzi
authors.initials: M
authors.lastname: Wasik
mesh_terms: D000367:Age Factors; D000368:Aged; D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D005260:Female; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D012307:Risk Factors; D014481:United States / Q000453:epidemiology
chemical_list: D050071:Bone Density Conservation Agents