title: Aggression in a patient with primary brain tumor: ethical implications for best management.
abstract: We present a case of a 55-year-old male diagnosed with glioblastoma (GB) involving the left frontal, parietal, and temporal lobes that developed aggression and committed a violent act against his wife. Aggression and violence have rarely been presented in the neuro-oncology literature, but have been well documented in stroke and dementia literature. We discuss the case along with the ethical principles as well as best management practices that may have been employed. As our therapies improve overall survival in brain tumors, aggression is an important behavior that the field must acknowledge.
authors.affiliation: Department of Medicine, Section of Hematology/Oncology, University of Illinois, 909 S. Wolcott Ave. Rm. 3133 (M/C 734), Chicago, IL 60612, USA. jvillano@uic.edu
authors.forename: J Lee
authors.initials: JL
authors.lastname: Villano
authors.forename: Nada
authors.initials: N
authors.lastname: Mlinarevich
authors.forename: Karriem S
authors.initials: KS
authors.lastname: Watson
authors.forename: Herbert H
authors.initials: HH
authors.lastname: Engelhard
authors.forename: Lisa
authors.initials: L
authors.lastname: Anderson-Shaw
mesh_terms: D000374:Aggression / Q000523:psychology*; D001932:Brain Neoplasms / Q000523:psychology* / Q000628:therapy; D004992:Ethics, Medical; D005909:Glioblastoma / Q000523:psychology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged