LOCKing in Cellular Potential.
Recently in Nature Genetics, Wen et al. (2009) report that H3K9me2 modification is more abundant in differentiated cells than in embryonic stem cells and that it decorates chromatin in repressive blocks.
Jørgensen
Helle F
HF
MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. helle.jorgensen@csc.mrc.ac.uk
Fisher
Amanda G
AG
D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D002843:Chromatin / Q000378:metabolism*; D053595:Embryonic Stem Cells / Q000378:metabolism / Q000502:physiology*; D020868:Gene Silencing / Q000187:drug effects; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008745:Methylation; D051379:Mice; D039904:Pluripotent Stem Cells / Q000378:metabolism / Q000502:physiology*
D002843:Chromatin; D006657:Histones