title: Passenger lymphocyte syndrome and liver transplantation.
abstract: The authors reviewed the passenger lymphocyte syndrome (PLS) that has appeared after transplantation. The definition, mechanism, serological, clinical features, and treatment for PLS after solid organ transplantation, especially liver transplantation, are described. The PLS refers to the clinical phenomenon of alloimmune hemolysis resulting from the adoptive transfer of viable lymphocytes from donor during solid organ or hematopoietic stem cell transplant. Sometimes, it is very severe and may cause "unexplained" hemolysis during the postoperative period. The authors reviewed literature about the PLS in liver transplantation.
authors.affiliation: Centre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Strasbourg, France.
authors.forename: Maxime
authors.initials: M
authors.lastname: Audet
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Panaro
authors.forename: Tullio
authors.initials: T
authors.lastname: Piardi
authors.forename: Ping
authors.initials: P
authors.lastname: Huang
authors.forename: Murat
authors.initials: M
authors.lastname: Cag
authors.forename: Jacques
authors.initials: J
authors.lastname: Cinqualbre
authors.forename: Philippe
authors.initials: P
authors.lastname: Wolf
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D006087:Graft vs Host Reaction / Q000276:immunology*; D006461:Hemolysis / Q000276:immunology; D006801:Humans; D016031:Liver Transplantation / Q000276:immunology*; D013577:Syndrome; D014184:Transplantation, Homologous / Q000276:immunology
chemical_list: D000017:ABO Blood-Group System