title: Context-dependent representation of reinforcement in monkey amygdala.
abstract: It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this study, we introduced three reinforcements (juice, water, and electrical stimulus) and used two of them in one experimental block. Of 52 neurons that showed cue responses reflecting the outcome information, 23% of amygdala neurons coded preferred outcomes, whereas only one neuron coded nonpreferred outcomes. These proportions of amygdala were significantly different from those of the orbitofrontal cortex, which had both types of neurons.
authors.affiliation: Primate Research Institute, Kyoto University, Inuyama, Aichi, Japan.
authors.forename: Daichi
authors.initials: D
authors.lastname: Hirai
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hosokawa
authors.forename: Masato
authors.initials: M
authors.lastname: Inoue
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Miyachi
authors.forename: Akichika
authors.initials: A
authors.lastname: Mikami
mesh_terms: D000200:Action Potentials; D000679:Amygdala / Q000502:physiology*; D000818:Animals; D003463:Cues; D004558:Electric Stimulation; D005502:Food; D008253:Macaca mulatta; D008839:Microelectrodes; D009474:Neurons / Q000502:physiology*; D012054:Reinforcement, Psychology; D012201:Reward