Evaluation on quality of life and analysis on its correlation with TCM syndromes in patients of chronic hepatitis B.
OBJECTIVE
To evaluate the quality of life (QOL) in patients with chronic hepatitis B (CHB) and analyze its correlation with traditional Chinese medicine (TCM) syndrome types.


METHODS
With cross-sectional investigation adopted, the QOL of 335 CHB patients was studied by the World Health Organization Quality of Life BREF Questionnaire (WHOQOL-BREF) and the chronic liver disease questionnaire (CLDQ). The results was compared with that of 30 healthy persons.


RESULTS
The QOL of the patients with chronic hepatitis B was lower than the healthy persons with signififi cant difference between them (P<0.01). Also it was different in patients of different TCM syndrome types (P<0.05 or P<0.01). The lowest QOL was shown in patients of the blood-stasis blocking vessel type and Gan ()-stagnation with Pi ()-defificiency type (P<0.01).


CONCLUSIONS
The QOL of CHB patients is lower than of healthy persons and closely correlated with TCM syndrome types.
Zhang
Wei
W
Department of Hepatopathy, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. ww44doctor@yahoo.com.cn
Wang
Li-Qiong
LQ
Liu
Yi-Bo
YB
D016022:Case-Control Studies; D006262:Health; D019694:Hepatitis B, Chronic / Q000473:pathology*; D006801:Humans; D008516:Medicine, Chinese Traditional; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013577:Syndrome; D014944:World Health Organization