Direct and short-time uptake of [70]fullerene into the cell membrane using an exchange reaction from a [70]fullerene-gamma-cyclodextrin complex and the resulting photodynamic activity.
[70]Fullerene (C70) was directly incorporated into the cell membrane using an exchange reaction from a C70-gamma-cyclodextrin (gamma-CDx) complex within 10 min and the incorporated C70 acted as a photodynamic sensitiser for a cancer cell.
Ikeda
Atsushi
A
Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan. aikeda@ms.naist.jp
Matsumoto
Masashi
M
Akiyama
Motofusa
M
Kikuchi
Jun-ichi
J
Ogawa
Takuya
T
Takeya
Tatsuo
T
D000042:Absorption; D002462:Cell Membrane / Q000502:physiology*; D037741:Fullerenes / Q000737:chemistry* / Q000493:pharmacokinetics; D006367:HeLa Cells; D006801:Humans; D046911:Macromolecular Substances / Q000737:chemistry; D008954:Models, Biological; D017319:Photosensitizing Agents / Q000737:chemistry*; D013053:Spectrophotometry; D047408:gamma-Cyclodextrins / Q000737:chemistry*
D037741:Fullerenes; D046911:Macromolecular Substances; D017319:Photosensitizing Agents; D047408:gamma-Cyclodextrins; C069836:fullerene C70; C023792:gamma-cyclodextrin