title: [A case of suspected idiopathic pulmonary upper lobe fibrosis (Amitani disease) with acute exacerbation].
abstract: An 82-year old man was admitted to our hospital for evaluation of progressive general malaise. He had previously been in good health. His chest roentgenogram showed reticular shadows and we suspected interstitial lung disease. On admission, his roentgenographic images showed deterioration compared with previous images. Acute lung injury was diagnosed by transbronchial lung biopsy, and steroid administration was started. He initially responded to treatment, but bilateral spontaneous pneumothorax occurred. Despite treatment, he died of respiratory failure. Amitani disease (idiopathic pulmonary upper lobe fibrosis) was suspected based on postmortem pathology, but his lung parenchyma was poor due to the presence of changes producing diffuse alveolar damage. We report and discuss this case because there are apparently no previous similar cases.
authors.affiliation: Department of Internal Medicine, Division of Respiratory Medicine, Nippon Medical School.
authors.forename: Takahito
authors.initials: T
authors.lastname: Nei
authors.forename: Masashi
authors.initials: M
authors.lastname: Kawamoto
authors.forename: Etsuko
authors.initials: E
authors.lastname: Satoh
authors.forename: Takio
authors.initials: T
authors.lastname: Takaku
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Seo
authors.forename: Taisuke
authors.initials: T
authors.lastname: Morimoto
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hattori
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Saito
authors.forename: Shinji
authors.initials: S
authors.lastname: Abe
authors.forename: Jiro
authors.initials: J
authors.lastname: Usuki
authors.forename: Arata
authors.initials: A
authors.lastname: Azuma
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nakayama
authors.forename: Yuh
authors.initials: Y
authors.lastname: Fukuda
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
authors.forename: Akihiko
authors.initials: A
authors.lastname: Gemma
mesh_terms: D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000503:physiopathology*