title: Are hemodynamic parameters predictors of mortality?
abstract: This article addresses a question that the authors consider to be somewhat rhetorical: are hemodynamic parameters predictors of mortality? It reviews the specific hemodynamic abnormalities and pathophysiologic consequences distinctive to the patient who has decompensation and addresses the data that implicate abnormal hemodynamics as a treatment target associated with increased mortality. The focus is on patients who have decompensated heart failure, defined as left ventricular systolic dysfunction and an acute, subacute, or gradual worsening of symptoms while receiving optimal medical therapy.
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA. garrie.haas@osumc.edu
authors.forename: Garrie J
authors.initials: GJ
authors.lastname: Haas
authors.forename: Carl V
authors.initials: CV
authors.lastname: Leier
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001835:Body Weight; D002302:Cardiac Output; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy / Q000401:mortality* / Q000503:physiopathology*; D006439:Hemodynamics; D006760:Hospitalization; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood; D011669:Pulmonary Wedge Pressure; D012680:Sensitivity and Specificity; D016277:Ventricular Function, Left / Q000502:physiology; D017725:Ventricular Pressure
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D020097:Natriuretic Peptide, Brain