title: Von Hippel-Lindau disease in pregnancy: a brief review.
abstract: The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical intervention should be considered with worsening clinical status. Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma.
authors.affiliation: Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Road, Stanford, California 94305, USA. mghayden@gmail.com
authors.forename: Melanie G
authors.initials: MG
authors.lastname: Hayden
authors.forename: Rosanne
authors.initials: R
authors.lastname: Gephart
authors.forename: Paul
authors.initials: P
authors.lastname: Kalanithi
authors.forename: Dean
authors.initials: D
authors.lastname: Chou
mesh_terms: D005260:Female; D018325:Hemangioblastoma / Q000150:complications / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D037841:Pregnant People; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology; D055815:Young Adult; D006623:von Hippel-Lindau Disease / Q000150:complications* / Q000209:etiology / Q000473:pathology* / Q000628:therapy