title: 3D pressure field in lipid membranes and membrane-protein complexes.
abstract: We calculate full 3D pressure fields for inhomogeneous nanoscale systems using molecular dynamics simulation data. The fields represent systems with increasing level of complexity, ranging from semivesicles and vesicles to membranes characterized by coexistence of two phases, including also a protein-membrane complex. We show that the 3D pressure field is distinctly different for curved and planar bilayers, the pressure field depends strongly on the phase of the membrane, and that an integral protein modulates the tension and elastic properties of the membrane.
authors.affiliation: Department of Physics, Tampere University of Technology, P.O. Box 692, FI-33101 Tampere, Finland.
authors.forename: O H Samuli
authors.initials: OH
authors.lastname: Ollila
authors.forename: H Jelger
authors.initials: HJ
authors.lastname: Risselada
authors.forename: Martti
authors.initials: M
authors.lastname: Louhivuori
authors.forename: Erik
authors.initials: E
authors.lastname: Lindahl
authors.forename: Ilpo
authors.initials: I
authors.lastname: Vattulainen
authors.forename: Siewert J
authors.initials: SJ
authors.lastname: Marrink
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000378:metabolism; D007473:Ion Channels / Q000737:chemistry / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D008563:Membrane Lipids / Q000737:chemistry* / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism; D008954:Models, Biological; D008956:Models, Chemical
chemical_list: D029968:Escherichia coli Proteins; D007473:Ion Channels; D008051:Lipid Bilayers; D008563:Membrane Lipids; D008565:Membrane Proteins; C086596:MscL protein, E coli; D015060:1,2-Dipalmitoylphosphatidylcholine