Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline.
Substantial progress has been made recently in understanding the genetic basis of cardiomyopathy. Cardiomyopathies with known genetic cause include hypertrophic (HCM), dilated (DCM), restrictive (RCM), arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and left ventricular noncompaction (LVNC). HCM, DCM, and RCM have been recognized as distinct clinical entities for decades, whereas ARVD/C and LVNC are relative newcomers to the field. Hence the clinical and genetic knowledge for each cardiomyopathy varies, as do the recommendations and strength of evidence.
Hershberger
Ray E
RE
Cardiovascular Division, University of Miami Miller School of Medicine, Miami, Florida 33101-5138, USA. rhershberger@med.miami.edu
Lindenfeld
Joann
J
Mestroni
Luisa
L
Seidman
Christine E
CE
Taylor
Matthew R G
MR
Towbin
Jeffrey A
JA
D009202:Cardiomyopathies / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D018570:Risk Assessment; D012955:Societies, Medical; D014481:United States