Exaggerated postsurgical inflammation in a patient with insufficiently treated Addison disease.
A patient with Addison disease developed fever, pain, and marked orbital inflammation 3 days after evisceration in the setting of perforated corneal ulcer. He was treated for presumed orbital cellulitis without improvement. Increasing the corticosteroid dose for his Addison disease resulted in complete resolution of the inflammation.
Hatton
Mark P
MP
Ophthalmic Consultants of Boston, Boston, Massachusetts 02114, USA. mphatton@eyeboston.com
Durand
Marlene L
ML
Burns
Sean M
SM
Hanna
Eissa
E
Jakobiec
Frederick A
FA
D000224:Addison Disease / Q000188:drug therapy* / Q000503:physiopathology; D003320:Corneal Ulcer / Q000150:complications; D003907:Dexamethasone / Q000008:administration & dosage*; D017234:Eye Evisceration / Q000009:adverse effects*; D005334:Fever / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054517:Orbital Cellulitis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D003907:Dexamethasone