Bilateral retrobulbar optic neuritis, Guillain-Barré syndrome and asymptomatic central white matter lesions following adult measles infection.
A 28-year-old woman presented with classic signs of measles and subsequently developed bilateral retro-bulbar optic neuritis and Guillain-Barré syndrome. Her radiographic and CSF findings were consistent with acute measles encephalitis. However, encephalopathy, such as behavioral changes and alteration in consciousness, was not presented. Improvements in the clinical, radiographic, and electrophysiological studies were observed during the steroid therapy. The overlap of CNS and PNS involvement as neurological complications of measles infection is very rare.
Tomiyasu
Kazuhiro
K
Department of Neurology, Saiseikai Utsunomiya Hospital, Tochigi. tomiyasu@ucatv.ne.jp
Ishiyama
Masaya
M
Kato
Kaiichiro
K
Komura
Masayoshi
M
Ohnuma
Eri
E
Inamasu
Joji
J
Takahashi
Toshiyuki
T
D000328:Adult; D002490:Central Nervous System / Q000503:physiopathology / Q000821:virology; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008457:Measles / Q000150:complications*; D008459:Measles virus / Q000472:pathogenicity; D009902:Optic Neuritis / Q000175:diagnosis / Q000209:etiology*; D017933:Peripheral Nervous System / Q000503:physiopathology / Q000821:virology; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis / Q000209:etiology*