title: MR imaging findings in 2 cases of late infantile GM1 gangliosidosis.
abstract: Late infantile GM1 gangliosidosis is a rare lysosomal disorder characterized by mental deterioration and progressive spastic, cerebellar, and extrapyramidal signs, without facial dysmorphisms and organomegaly. Neuroimaging findings have been reported in only a few cases. Here we report on predominant globus pallidus MR signal-intensity abnormalities in 2 patients with the late infantile form of GM1 gangliosidosis.
authors.affiliation: Division of Child Neuropsychiatry, Gaslini Institute, University of Genoa, Genoa, Italy. elisadegrandis@yahoo.it
authors.forename: E
authors.initials: E
authors.lastname: De Grandis
authors.forename: M
authors.initials: M
authors.lastname: Di Rocco
authors.forename: A
authors.initials: A
authors.lastname: Pessagno
authors.forename: E
authors.initials: E
authors.lastname: Veneselli
authors.forename: A
authors.initials: A
authors.lastname: Rossi
mesh_terms: D001921:Brain / Q000473:pathology*; D002648:Child; D005260:Female; D016537:Gangliosidosis, GM1 / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D055815:Young Adult