title: Effects of childhood and middle-adulthood family conditions on later-life mortality: evidence from the Utah Population Database, 1850-2002.
abstract: We examine how key early family circumstances affect mortality risks decades later. Early-life conditions are measured by parental mortality, parental fertility (e.g., offspring sibship size, parental age at offspring birth), religious upbringing, and parental socioeconomic status. Prior to these early-life conditions are familial and genetic factors that affect life span. Accordingly, we consider the role of parental and familial longevity on adult mortality risks. We analyze the large Utah Population Database which contains a vast amount of genealogical and other vital/health data that contain full life histories of individuals and hundreds of their relatives. To control for unobserved heterogeneity, we analyze sib-pair data for 12,000 sib-pairs using frailty models. We found modest effects of key childhood conditions (birth order, sibship size, parental religiosity, parental SES, and parental death in childhood). Our measures of familial aggregation of longevity were large and suggest an alternative view of early-life conditions.
authors.affiliation: University of Utah, Salt Lake City, Utah, United States. ken.smith@fcs.utah.edu
authors.forename: Ken R
authors.initials: KR
authors.lastname: Smith
authors.forename: Geraldine P
authors.initials: GP
authors.lastname: Mineau
authors.forename: Gilda
authors.initials: G
authors.lastname: Garibotti
authors.forename: Richard
authors.initials: R
authors.lastname: Kerber
mesh_terms: D000328:Adult; D000367:Age Factors; D001722:Birth Order; D002648:Child; D015988:Cohort Effect; D005191:Family Characteristics; D005260:Female; D005298:Fertility; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008016:Life Change Events; D008136:Longevity / Q000235:genetics*; D008297:Male; D009026:Mortality / Q000266:history*; D016016:Proportional Hazards Models; D012067:Religion / Q000266:history; D012307:Risk Factors; D035781:Siblings; D012923:Social Class; D014589:Utah / Q000453:epidemiology