Retinal blood flow detection in diabetic patients by Doppler Fourier domain optical coherence tomography.
We present human retinal blood flow investigation for diabetic patients using Doppler Fourier domain optical coherence tomography (FDOCT). The scanning pattern consisted of two concentric circles around the optic nerve head. The blood flow in one patient with diabetes and no retinpathy and another patient with treated proliferative diabetic retinopathy were measured. The patient without retinopathy showed a total blood flow value at the lower level of the normal range. The flow distribution between superior and inferior retina was balanced. The patient with diabetic retinopathy had a flow value lower than the normal people. Our study shows that Doppler FD-OCT can be used to evaluate the total retinal blood flow in patients with retinal diseases.
Wang
Yimin
Y
Center for Ophthalmic Optics & Lasers, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. yiminwan@usc.edu
Fawzi
Amani
A
Tan
Ou
O
Gil-Flamer
John
J
Huang
David
D
D000328:Adult; D001783:Blood Flow Velocity; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003930:Diabetic Retinopathy / Q000503:physiopathology*; D004301:Doppler Effect; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008962:Models, Theoretical; D012039:Regional Blood Flow; D012171:Retinal Vessels / Q000503:physiopathology*; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000706:statistics & numerical data