Solid-phase based total synthesis of Jasplakinolide by ring-closing metathesis.
The study of classical ring-closing metathesis and relay ring-closing metathesis in a total synthesis of Jasplakinolide and its desbromo analog is described.
Tannert
René
R
Technische Universität Dortmund, Fakultät Chemie, Otto-Hahn-Str. 6, D-44227, Dortmund, Germany.
Hu
Tai-Shan
TS
Arndt
Hans-Dieter
HD
Waldmann
Herbert
H
D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D047630:Depsipeptides; C540619:desbromo jasplakinolide; C057531:jasplakinolide