The role of paroxetine in fatigue and depression of patients under chemotherapeutic treatment.
We evaluated paroxetine for the treatment of fatigue and depression in patients with solid tumors after chemotherapy, and we found that paroxetine is effective for the treatment of depression during chemotherapy but has no benefit for the treatment of fatigue.
Heras
Panagiotis
P
Department of Internal Medicine, General Hospital of Nafplion, Nafplion, Greece. panheras@yahoo.com
Kritikos
Konstantinos
K
Hatzopoulos
Antonios
A
Kritikos
Nikolaos
N
Heras
Vasileios
V
Mitsibounas
Dimitrios
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003863:Depression / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005221:Fatigue / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000627:therapeutic use*; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
D018687:Antidepressive Agents, Second-Generation; D000970:Antineoplastic Agents; D017374:Paroxetine