title: "Mycobacterium tilburgii," a newly described, uncultivated opportunistic pathogen.
abstract: Molecular methods are increasingly used to identify pathogens that are difficult to cultivate. We report a case of disseminated infection with "Mycobacterium tilburgii," a proposed species that has never been cultivated. The case illustrates the diagnostic utility of sequence analysis of the 16S rRNA gene directly from clinical specimens.
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. tpalmore@mail.nih.gov
authors.forename: Tara N
authors.initials: TN
authors.lastname: Palmore
authors.forename: Yvonne R
authors.initials: YR
authors.lastname: Shea
authors.forename: Patricia S
authors.initials: PS
authors.lastname: Conville
authors.forename: Frank G
authors.initials: FG
authors.lastname: Witebsky
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Anderson
authors.forename: Irene P
authors.initials: IP
authors.lastname: Rupp Hodge
authors.forename: Steven M
authors.initials: SM
authors.lastname: Holland
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D006801:Humans; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification* / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000382:microbiology*; D009894:Opportunistic Infections / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D011860:Radiography, Abdominal; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S