title: Fibroepithelioma of Pinkus with pleomorphic epithelial giant cells.
abstract: Fibroepithelioma of Pinkus is a rare, indolent variant of basal cell carcinoma (BCC). The presence of pleomorphic giant cells in such a tumor is extremely rare and to our knowledge, only one such case has been previously reported in the literature. We report another case occurring as a pedunculated, gluteal lesion in an 82-year-old man. The nodule was lightly pigmented, polypoid, and measured 1.0 cm in greatest dimension. Immunohistochemical staining confirmed that the giant cells were of epithelial origin and that the proliferative rate of these cells was low.
authors.affiliation: Department of Pathology, Creighton University Medical Center, Omaha, Nebraska, USA.
authors.forename: Susan K
authors.initials: SK
authors.lastname: Repertinger
authors.forename: Todd
authors.initials: T
authors.lastname: Stevens
authors.forename: Nicholas
authors.initials: N
authors.lastname: Markin
authors.forename: Heather
authors.initials: H
authors.lastname: Klepacz
authors.forename: Deba P
authors.initials: DP
authors.lastname: Sarma
mesh_terms: D000369:Aged, 80 and over; D002081:Buttocks; D002280:Basal Cell Carcinoma / Q000145:classification / Q000378:metabolism / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology*; D049109:Cell Proliferation; D015726:Giant Cells / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D018225:Neoplasms, Fibroepithelial / Q000378:metabolism / Q000473:pathology*; D013194:Staining and Labeling