Pancreatic cancer and pancreaticoduodenectomy in elderly patient: morbidity and mortality are increased. Is it the real life?
OBJECTIVE
The aim of this study was to compare post-operative outcomes of two groups of patients aged more or less than 70 years old


METHODS
From January 1990 to January 2006, 150 patients underwent pancreaticoduodenectomy (PD) for pancreatic adenocarcinomas (PA) were reviewed at the Department of Digestive Surgery of University Hospital. Twenty five patients Group A> or =70 and Group B<70 years old, were well matched for gender, diagnosis, body mass index, American Society of Anesthesiologists (ASA) score, and texture of pancreatic parenchyma.


RESULTS
There was no intraoperative death. Mean operative hospital and intensive care unit stays were in Group A, B: 21+/-9; 4.5+/-8 vs. 19+/-7; 3+/-3 NS respectively. There were four deaths in A and no death in B at three months of hospital discharge. More patients had complications in Group A (56% vs 36% NS). Medical complications seem to be more frequent in Group A (40%vs 12% NS). The median survivals were 20 and 27 months for A and B, respectively.


CONCLUSIONS
We observed an increased rate of morbidity and mortality in patients aged more than 70 years.
Ouaïssi
Mehdi
M
Pôle d'oncologie et spécialités Médico-chirurgicales, Service de chirurgie digestive et oncologique, Hôpital Timone, Marseille, France. mehdi.ouaissi@mail.ap-hm.fr
Sielezneff
Igor
I
Pirrò
Nicolas
N
Merad
Abelrahmane
A
Loundou
Anderson
A
Chaix
Jean Baptiste
JB
Dahan
Laetitia
L
Ries
Pauline
P
Seitz
Jean François
JF
Payan
Marie José
MJ
Consentino
Bernard
B
Sastre
Bernard
B
D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D009017:Morbidity; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome