title: Takotsubo cardiomyopathy during acute adrenal crisis due to isolated adrenocorticotropin deficiency.
abstract: We report a 69-year-old woman who had isolated adrenocorticotropic hormone (ACTH) deficiency. Subsequently, she had Takotsubo cardiomyopathy during acute adrenal crisis. Replacement therapy with hydrocortisone sufficiently improved her cardiomyopathy. We conclude that her myocardial dysfunction was closely related to adrenal insufficiency and suggest that in certain circumstances, adrenal crisis may cause Takotsubo cardiomyopathy.
authors.affiliation: The Second Department of Internal Medicine, Kansai Medical University, Osaka. ukitac@hirakata.kmu.ac.jp
authors.forename: Chizuko
authors.initials: C
authors.lastname: Ukita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Miyazaki
authors.forename: Nagaoki
authors.initials: N
authors.lastname: Toyoda
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kosaki
authors.forename: Mitsushige
authors.initials: M
authors.lastname: Nishikawa
authors.forename: Toshiji
authors.initials: T
authors.lastname: Iwasaka
mesh_terms: D000309:Adrenal Insufficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D000368:Aged; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone