title: [Case of villous tumor of the rectum presenting with severe diarrhea and electrolyte depletion syndrome].
abstract: A 83-year-old man with a 2-year history of diarrhea was admitted hospital because of increased diarrhea and general fatigue. He had severe dehydration, hyponatremia, hypokalemia and hypochloremia. Abdominal CT showed tumor and fluid in the rectum. Colonoscopy revealed large tumor with a villous structure in the rectum. Low anterior resection was performed. The histopathological diagnosis was adenocarcinoma with villous adenoma. The immunostaining of the tumor revealed positive COX-2 expression. The diarrhea and electrolyte disturbance disappeared after the resection of tumor.
authors.affiliation: Division of Medicine and Clinical Science, Tottori University, Japan. yasugi@med.tottori-u.ac.jp
authors.forename: Akiko
authors.initials: A
authors.lastname: Yasugi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuoka
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Otani
authors.forename: Kazunori
authors.initials: K
authors.lastname: Maeda
authors.forename: Kazuya
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Masaharu
authors.initials: M
authors.lastname: Koda
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kawaguchi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Harada
authors.forename: Kazuo
authors.initials: K
authors.lastname: Yashima
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Murawaki
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Horie
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D018253:Adenoma, Villous / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000369:Aged, 80 and over; D003681:Dehydration / Q000209:etiology; D003967:Diarrhea / Q000209:etiology*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary; D012004:Rectal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012720:Severity of Illness Index; D013577:Syndrome; D014883:Water-Electrolyte Imbalance / Q000209:etiology*