Long-term management of craniofacial osteosarcoma.
Primary osteosarcoma of the calvarium is rare. A 22-year-old female patient was admitted for a progressively enlarging, indurated mass under her scalp for 6 months. A computed tomographic scan revealed a 4 x 3 x 2-cm3 osteolytic lesion over the right parietal cortex with a sunburst appearance. The patient underwent en bloc tumor resection using bicortical parietal craniectomy with a 2-cm margin of normal bone, including the tightly adherent periosteum over the tumor. Immediate cranioplasty was performed with split-thickness autogenous calvarial bone grafts. Histopathologic examination showed the tumor to be a primary high-grade osteosarcoma of the skull. She received postoperative chemotherapy. She has recovered well and remains without any evidence of disease at her most recent, 8-year follow-up. The key to disease-free survival in treating primary osteosarcoma of the calvarium is complete surgical resection with immediate reconstruction followed by adjuvant chemotherapy.
Chou
Erh-Kang
EK
Department of Plastic Surgery, School of Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Chang
Chun-Shin
CS
Chen
Philip Kuo-Ting
PK
Chen
Yu-Ray
YR
Yu
Jack Chung-Kai
JC
Jung
Shih-Ming
SM
Chang
Sophia Chia-Ning
SC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods; D017024:Chemotherapy, Adjuvant; D003399:Craniotomy / Q000379:methods; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D012516:Osteosarcoma / Q000601:surgery*; D010294:Parietal Bone / Q000601:surgery*; D010521:Periosteum / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods; D012888:Skull Neoplasms / Q000601:surgery*; D055815:Young Adult