title: Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management.
abstract: This review describes the microbiology, and medical management of orbital and intracranial complications of sinusitis in children. The most common complications are orbital cellulitis, subperiosteal abscess, orbital abscess, brain abscess, subdural empyema and meningitis. The predominate organisms recovered from these infection are anaerobic, aerobic, and microaerophilic bacteria of oral flora origin. Establishing the microbiology by obtaining appropriate cultures for both aerobic and anaerobic bacteria are essential for proper antimicrobial selection. Early recognition and appropriate surgical and medical therapy are essential to ensure recovery.
authors.affiliation: Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle Street NW, Washington, DC 20016, USA. ib6@georgetown.edu
authors.forename: Itzhak
authors.initials: I
authors.lastname: Brook
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000188:drug therapy / Q000382:microbiology*; D020806:Central Nervous System Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D009916:Orbital Diseases / Q000188:drug therapy / Q000382:microbiology*; D010522:Periostitis / Q000188:drug therapy / Q000382:microbiology*; D012852:Sinusitis / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents