title: Structure elucidation and NMR assignments of two new pyrrolidinyl quinoline alkaloids from chestnut honey.
abstract: The complete (1)H, (13)C and (15)N NMR spectral assignments of two new alkaloids isolated from chestnut honey and structurally related to kynurenic acid have been made using 1-D and 2-D NMR techniques, including COSY, HMQC and HMBC experiments. The new compounds have been identified as 3-(2'-pyrrolidinyl)-kynurenic acid and its gamma-lactam derivative.
authors.affiliation: Department of Pharmaceutical Sciences Pietro Pratesi, University of Milan, via Mangiagalli 25, 20133 Milan, Italy. giangiacomo.beretta@unimi.it
authors.forename: Giangiacomo
authors.initials: G
authors.lastname: Beretta
authors.forename: Giulio
authors.initials: G
authors.lastname: Vistoli
authors.forename: Enrico
authors.initials: E
authors.lastname: Caneva
authors.forename: Cecila
authors.initials: C
authors.lastname: Anselmi
authors.forename: Roberto
authors.initials: R
authors.lastname: Maffei Facino
mesh_terms: D031319:Aesculus / Q000737:chemistry*; D000470:Alkaloids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D006722:Honey / Q000032:analysis*; D007736:Kynurenic Acid / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D011759:Pyrrolidines / Q000032:analysis* / Q000737:chemistry; D011804:Quinolines / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: C540397:3-(2'-pyrrolidinyl)-kynurenic acid; D000470:Alkaloids; D011759:Pyrrolidines; D011804:Quinolines; D007736:Kynurenic Acid