title: [Effect of atractylodes rhizome oil and other volatile oils on percutaneous absorption of baicalin].
abstract: OBJECTIVE
  To study the effects of atractylodes rhizome oil, patchouli oil, angelica volatile oil on the transdermal delivery of baicalin.
  
  
  METHODS
  The modified Valia-Chien diffusion cells was used. With saline isotonic solution as receptor fluid and different concentration of atractylodes rhizome oil, patchouli oil, angelica volatile oil as enhancers, the cumulative amount of baicalin penatrating through the skin was determined in vitro.
  
  
  RESULTS
  All the three volatile oils improved the skin penetration of baicalin, and the effect of atractylodes rhizome oil was the best.
  
  
  CONCLUSIONS
  Atractylodes rhizome oil is an effective enhancer for percutaneous penetration of baicalin.
authors.affiliation: Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
authors.forename: Mao-Fu
authors.initials: MF
authors.lastname: Luo
authors.forename: Qi
authors.initials: Q
authors.lastname: Shen
authors.forename: Tong
authors.initials: T
authors.lastname: Zhang
authors.forename: Yue-Hong
authors.initials: YH
authors.lastname: Xu
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D031174:Atractylodes / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000493:pharmacokinetics*; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology*; D010539:Permeability / Q000187:drug effects; D010938:Plant Oils / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D031364:Scutellaria baicalensis / Q000737:chemistry*; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D012869:Skin Absorption / Q000187:drug effects*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D009822:Oils, Volatile; D010938:Plant Oils; C038044:baicalin