[A case of suspected idiopathic pulmonary upper lobe fibrosis (Amitani disease) with acute exacerbation].
An 82-year old man was admitted to our hospital for evaluation of progressive general malaise. He had previously been in good health. His chest roentgenogram showed reticular shadows and we suspected interstitial lung disease. On admission, his roentgenographic images showed deterioration compared with previous images. Acute lung injury was diagnosed by transbronchial lung biopsy, and steroid administration was started. He initially responded to treatment, but bilateral spontaneous pneumothorax occurred. Despite treatment, he died of respiratory failure. Amitani disease (idiopathic pulmonary upper lobe fibrosis) was suspected based on postmortem pathology, but his lung parenchyma was poor due to the presence of changes producing diffuse alveolar damage. We report and discuss this case because there are apparently no previous similar cases.
Nei
Takahito
T
Department of Internal Medicine, Division of Respiratory Medicine, Nippon Medical School.
Kawamoto
Masashi
M
Satoh
Etsuko
E
Takaku
Takio
T
Seo
Yoshitsugu
Y
Morimoto
Taisuke
T
Hattori
Kumiko
K
Saito
Yoshinobu
Y
Abe
Shinji
S
Usuki
Jiro
J
Azuma
Arata
A
Nakayama
Tomoko
T
Fukuda
Yuh
Y
Kudoh
Shoji
S
Gemma
Akihiko
A
D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000503:physiopathology*