title: Pupillometric characteristics in patients with choroidal neovascularization due to age-related macular degeneration.
abstract: OBJECTIVE
  To study the pupillary light reflex in patients with choroidal neovascularization due to age-related macular degeneration (AMD).
  
  
  METHODS
  The study included 15 patients with AMD and 15 control subjects. A full recording of the pupil's reaction to light was registered and the following eight parameters were measured and reported: baseline pupil (R1), latency (T1), minimum pupil radius (R2), amplitude (AMP), maximum constriction velocity (VCmax), maximum constriction acceleration (ACmax), time for maximum velocity (T2), and time for maximum constriction (T3).
  
  
  RESULTS
  All variables measured presented alterations in the AMD group and a number of them were significantly reduced in the AMD group.
  
  
  CONCLUSIONS
  The presence of neovascular AMD significantly affects the pupil's response to light stimulus when compared to normal subjects.
authors.affiliation: Laboratory of Clinical Neurophysiology, Aristotle University of Thessaloniki, Thessaloniki - Greece. brozou@yahoo.com
authors.forename: Catherine
authors.initials: C
authors.lastname: Brozou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Fotiou
authors.forename: Sofia
authors.initials: S
authors.lastname: Androudi
authors.forename: Evelyn
authors.initials: E
authors.lastname: Theodoridou
authors.forename: Charalambos
authors.initials: C
authors.lastname: Giantselidis
authors.forename: Alexandros
authors.initials: A
authors.lastname: Alexandridis
authors.forename: Periklis
authors.initials: P
authors.lastname: Brazitikos
mesh_terms: D020256:Choroidal Neovascularization / Q000209:etiology / Q000503:physiopathology*; D003623:Dark Adaptation; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008027:Light; D008268:Macular Degeneration / Q000150:complications / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology* / Q000528:radiation effects; D011681:Pupil Disorders / Q000503:physiopathology*; D012025:Reflex, Pupillary / Q000502:physiology*