title: Obesity and the metabolic syndrome in a student cohort from Southern Italy.
abstract: OBJECTIVE
  Cardiovascular (CV) risk factors present in childhood predict future CV events. Few data regarding the metabolic syndrome (MS) prevalence are available in adolescents from Mediterranean areas where obesity is becoming a social emergency. This study presents data of MS prevalence in a student cohort from southern Italy.
  
  
  RESULTS
  1629 students between 7 and 14 years of age underwent anthropometric measurements and a blood sample was obtained to assess biochemical parameters. MS risk factors were calculated based on age and gender adjusted percentiles of parameter distributions. MS prevalence rate was 0.022 using paediatric, age-adjusted criteria; the rate increased to 0.029 using a 90th percentile criteria for fasting blood glucose instead of >100mg/dL. Using the criteria issued by the International Diabetes Federation the MS prevalence rate dropped to 0.005. The exploratory factor analysis identified four factors: age/fat related, lipids, blood pressure and blood glucose. Family history of type 2 diabetes mellitus was associated with triglyceride [OR=1.55 (1.0-2.3)] and BMI [OR=1.71 (1.2-2.4)] but not to blood glucose by logistic regression analysis.
  
  
  CONCLUSIONS
  In a student cohort from Southern Italy, obesity is associated with the features of MS.
authors.affiliation: Department of Clinical Medicine and Emerging Diseases, University of Palermo, Palermo, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Noto
authors.forename: T
authors.initials: T
authors.lastname: Niglio
authors.forename: A B
authors.initials: AB
authors.lastname: Cefalù
authors.forename: E
authors.initials: E
authors.lastname: Martino
authors.forename: F
authors.initials: F
authors.lastname: Fayer
authors.forename: M
authors.initials: M
authors.lastname: Mina
authors.forename: V
authors.initials: V
authors.lastname: Valenti
authors.forename: A
authors.initials: A
authors.lastname: Notarbartolo
authors.forename: M
authors.initials: M
authors.lastname: Averna
authors.forename: F
authors.initials: F
authors.lastname: Martino
mesh_terms: D000293:Adolescent; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002648:Child; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D009765:Obesity / Q000453:epidemiology*; D050177:Overweight / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D013334:Students / Q000706:statistics & numerical data*