title: Idiopathic spinal cord herniation: case report and review of the literature.
abstract: BACKGROUND
  Idiopathic spinal cord herniation (ISCH) is a rare cause of progressive myelopathy frequently present in Brown-Séquard syndrome. Preoperative diagnosis can be made with magnetic resonance imaging (MRI). Many surgical techniques have been applied by various authors and are usually reversible by surgical treatment.
  
  
  METHODS
  Case report and review of the literature.
  
  
  RESULTS
  A 45-year-old woman with Brown-Séquard syndrome underwent thoracic MRI, which revealed transdural spinal cord herniation at T8 vertebral body level. During surgery the spinal cord was reduced and the ventral dural defect was restorated primarily and reinforced with a thin layer of subdermal fat. The dural defect was then closed with interrupted stitches.
  
  
  RESULTS
  Although neurologic status improved postoperatively, postsurgical MRI demonstrated swelling and abnormal T2-signal intensity in the reduced spinal cord. Review of the English language literature revealed 100 ISCH cases.
  
  
  CONCLUSIONS
  ISCH is a rare clinical entity that should be considered in differential diagnosis of Brown-Séquard syndrome, especially among women in their fifth decade of life. Outcome for patients who initially had Brown-Séquard syndrome was significantly better than for patients who presented with spastic paralysis. Although progression of neurologic deficits can be very slow, reduction of the spinal cord and repair of the defect are crucial in stopping or reversing the deterioration.
authors.affiliation: Neurosurgery Department, VKF American Hospital, Istanbul, Turkey. sasanim@gmail.com
authors.forename: Mehdi
authors.initials: M
authors.lastname: Sasani
authors.forename: Ali F
authors.initials: AF
authors.lastname: Ozer
authors.forename: Metin
authors.initials: M
authors.lastname: Vural
authors.forename: Ali C
authors.initials: AC
authors.lastname: Sarioglu
mesh_terms: D018437:Brown-Sequard Syndrome / Q000209:etiology* / Q000601:surgery; D005260:Female; D006547:Hernia / Q000150:complications*; D059685:Herniorrhaphy; D006801:Humans; D007796:Laminectomy / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000150:complications* / Q000601:surgery