Von Hippel-Lindau disease in pregnancy: a brief review.
The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical intervention should be considered with worsening clinical status. Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma.
Hayden
Melanie G
MG
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Road, Stanford, California 94305, USA. mghayden@gmail.com
Gephart
Rosanne
R
Kalanithi
Paul
P
Chou
Dean
D
D005260:Female; D018325:Hemangioblastoma / Q000150:complications / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D037841:Pregnant People; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology; D055815:Young Adult; D006623:von Hippel-Lindau Disease / Q000150:complications* / Q000209:etiology / Q000473:pathology* / Q000628:therapy