[Cytokines and the liver].
The cytokines are proteins synthetized by lymphoid and monocyte/macrophage system cells in response to a wide variety of infectious stimulus, featuring bacterial endotoxins. These proteins have immunoregulatory effects and have been implicated in inflammation and fibrosis. In this review we refer to the interleukin-1, interleukin-6 and tumor necrosis factor because of their elevated basal levels in acute and chronic hepatopaties and in response to lipopolisacharide mainly in alcoholic liver disease.
Kershenobich
D
D
Departamento de Gastroenterología, Instituto Nacional de la Nutrición "Salvador Zubirán", Vasco de Quiroga No. 15, Tlalpan, C.P. 14000 México, DF.
Borovoy
J
J
Guevara
L
L
Male
R
R
Alcocer
J
J
D016207:Cytokines / Q000502:physiology*; D019446:Endotoxemia / Q000503:physiopathology; D006801:Humans; D007239:Infections / Q000503:physiopathology; D007375:Interleukin-1 / Q000502:physiology; D015850:Interleukin-6 / Q000502:physiology; D007962:Leukocytes / Q000378:metabolism; D008099:Liver / Q000502:physiology*; D008107:Liver Diseases / Q000503:physiopathology; D022423:Myeloid Cells / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology
D016207:Cytokines; C508600:IL6 protein, human; D007375:Interleukin-1; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha