title: Isolation and characterization of a new hispolone derivative from antioxidant extracts of Pistacia atlantica.
abstract: The quantification of the total phenolic compounds of Pistacia atlantica showed that the different parts of the tree are rich in natural phenolic compounds. The antioxidant tests proved that the phenolic extracts have a strong antioxidant activity. The positive correlation between the Trolox equivalent antioxidant capacity (TEAC) and the amount of phenolic compounds confirms their contribution to the antioxidant activity. Among the various phenolic compounds isolated and characterized by spectroscopic methods, a new natural antioxidant 1 (methyl 5-(3,4-dihydroxyphenyl)-3-hydroxypenta-2,4-dienoate) derived from hispolone 2 has been isolated from the mushroom Inonotus hispidus growing on Pistacia atlantica. Hispolone 2 (6-(3,4-dihydroxyphenyl)-4-hydroxyhexa-3,5-dien-2-one) and hispidin 3 (6-(2-(3,4-dihydroxyphenyl)vinyl)-4-hydroxy-2H-pyran-2-one) have been also identified using spectroscopic methods, including 2D-NMR and EI-MS.
authors.affiliation: Laboratoire des Sciences Fondamentales, Université Amar Telidji, Laghouat, BP37G 03000, Laghouat, Algeria. med_yousfi@hotmail.com
authors.forename: Mohamed
authors.initials: M
authors.lastname: Yousfi
authors.forename: Amar
authors.initials: A
authors.lastname: Djeridane
authors.forename: Isabelle
authors.initials: I
authors.lastname: Bombarda
authors.forename: Bernard
authors.initials: B
authors.lastname: Duhem
authors.forename: Emile M
authors.initials: EM
authors.lastname: Gaydou
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D001487:Basidiomycota / Q000737:chemistry; D002396:Catechols / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D005707:Gallic Acid / Q000737:chemistry / Q000302:isolation & purification; D047311:Luteolin / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D027927:Pistacia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C544869:6-(3,4-dihydroxyphenyl)-4-hydroxyhexa-3,5-dien-2-one; D000975:Antioxidants; D002396:Catechols; D010636:Phenols; D010936:Plant Extracts; D011753:Pyrones; C544868:methyl 5-(3,4-dihydroxyphenyl)-3-hydroxypenta-2,4-dienoate; D005707:Gallic Acid; D047311:Luteolin; C007946:hispidin