Decoupling the cortical power spectrum reveals real-time representation of individual finger movements in humans.
During active movement the electric potentials measured from the surface of the motor cortex exhibit consistent modulation, revealing two distinguishable processes in the power spectrum. At frequencies <40 Hz, narrow-band power decreases occur with movement over widely distributed cortical areas, while at higher frequencies there are spatially more focal power increases. These high-frequency changes have commonly been assumed to reflect synchronous rhythms, analogous to lower-frequency phenomena, but it has recently been proposed that they reflect a broad-band spectral change across the entire spectrum, which could be obscured by synchronous rhythms at low frequencies. In 10 human subjects performing a finger movement task, we demonstrate that a principal component type of decomposition can naively separate low-frequency narrow-band rhythms from an asynchronous, broad-spectral, change at all frequencies between 5 and 200 Hz. This broad-spectral change exhibited spatially discrete representation for individual fingers and reproduced the temporal movement trajectories of different individual fingers.
Miller
K J
KJ
Department of Physics, Seattle Children's Research Institute and Department of Neurological Surgery, University of Washington, Seattle, Washington 98195, USA. kjmiller@u.washington.edu
Zanos
S
S
Fetz
E E
EE
den Nijs
M
M
Ojemann
J G
JG
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping / Q000379:methods; D002540:Cerebral Cortex / Q000502:physiology; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D005385:Fingers / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D011597:Psychomotor Performance / Q000502:physiology; D013997:Time Factors; D055815:Young Adult