Effect of demographic and clinicopathologic factors on prognosis of early gastric cancer in Iran.
BACKGROUND
The aim of this study was to estimate some prognostic factors that affect on overall survival of patients with early gastric cancer.


METHODS
A retrospective study had been done on patients diagnosed with early gastric cancer who registered in cancer registry center, Tehran, Iran, between December 21, 2001 and December 21, 2006 and all patients were followed by telephone contacts. The Kaplan-Meier method was performed to describe survival curves and log-rank test to compare the survival rate in subgroups. Cox regression was used to determine the prognosis factors.


RESULTS
The mean age was 57.9 years and 72.6% of patients were male. Tumor size (>35 mm) and lymph node metastasis were established as significant factors for survival of patients with EGC in both univariate and multivariate analysis.


CONCLUSIONS
The findings of this study indicate that lymph node metastasis and tumor size are the most independent prognostic factors in these patients.
Moghimi-Dehkordi
Bijan
B
Research Center for Gastroenterology and Liver Diseases, Shaheed Beheshti University, MC, Tehran, Iran. b_moghimi_de@ yahoo.com
Safaee
Azadeh
A
Pourhoseingholi
Mohamad Amin
MA
Zali
Mohammad Reza
MR
D017677:Age Distribution; D000368:Aged; D001707:Biopsy, Needle; D002423:Cause of Death; D015331:Cohort Studies; D003131:Combined Modality Therapy; D003710:Demography; D003906:Developing Countries; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009367:Neoplasm Staging; D011336:Probability; D011379:Prognosis; D016016:Proportional Hazards Models; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D017678:Sex Distribution; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D016019:Survival Analysis