Outcomes of hepatic resection for hepatolithiasis.
BACKGROUND
Hepatic resection is main approach to treatment of hepatolithiasis, but the long-term follow-up results of hepatic resection for hepatolithiasis are rarely reported.


METHODS
A retrospective study was conducted of 87 patients with hepatolithiasis who underwent hepatic resection.


RESULTS
The final stone clearance rates were 95%. There was a significant difference in the incidence of recurrent stones between patients with and without remaining biliary strictures. On multivariate analysis, the presence of residual or recurrent stones was an independent risk factor associated with recurrent cholangitis. The 10-year overall survival rate was 80.3%. On multivariate analysis, the development of cholangiocarcinoma was an independent predictor of survival in patients who underwent hepatic resection for hepatolithiasis.


CONCLUSIONS
The long-term outcomes after hepatic resection were satisfactory in patients whose intrahepatic stones and strictures were completely removed. Cholangiocarcinoma associated with hepatolithiasis was an independent prognostic factor in patients with hepatolithiasis who underwent hepatic resection.
Uenishi
Takahiro
T
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan. m6877710@msic.med.osaka-cu.ac.jp
Hamba
Hiroyuki
H
Takemura
Shigekazu
S
Oba
Kazuki
K
Ogawa
Masao
M
Yamamoto
Takatsugu
T
Tanaka
Shogo
S
Kubo
Shoji
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000175:diagnosis / Q000401:mortality; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000175:diagnosis / Q000401:mortality; D002761:Cholangitis / Q000453:epidemiology; D005260:Female; D006498:Hepatectomy; D006801:Humans; D033162:Incidental Findings; D020347:Lithiasis / Q000401:mortality / Q000601:surgery*; D008107:Liver Diseases / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors