A case study of delayed HIV-1 seroconversion highlights the need for Combo assays.
This report describes a case in which a patient took at least four months to seroconvert to anti-HIV positivity. A concomitant CMV infection probably contributed to the profound immune suppression observed. It is essential that fourth generation HIV antigen/antibody combo assays be used to ensure that such cases are not missed.
Skidmore
S
S
Department of Microbiology, Shrewsbury and Telford Hospital NHS Trust, Telford TF1 6TF, UK. sue.skidmore@sath.nhs.uk
Devendra
S
S
Weaver
J
J
Short
J
J
Osman
H
H
Smit
E
E
D015492:AIDS Serodiagnosis; D017088:AIDS-Related Opportunistic Infections; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D045363:Pneumocystis carinii / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000150:complications; D013997:Time Factors; D055815:Young Adult