Recurrent fever and rash.
Periodic fever is uncommon in children. The differential diagnosis is large, even though associated symptoms such as rash may help narrow the differential diagnosis. Atypical presentations require thoughtful evaluation. This article describes a case of a 4-year-old boy who presented to the emergency department with recurrent fever, vomiting, abdominal pain, myalgias, and rash. His hospital course is described along with a review on the background, evaluation, management, and complications of tumor necrosis receptor-1 alpha periodic syndrome.
Cashen
Katherine
K
Carman and Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan, USA.
Kamat
Deepak
D
D015746:Abdominal Pain / Q000209:etiology; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology*; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005334:Fever / Q000209:etiology*; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications; D008297:Male; D018124:Receptors, Tumor Necrosis Factor / Q000097:blood; D016896:Treatment Outcome; D014839:Vomiting / Q000209:etiology
D018124:Receptors, Tumor Necrosis Factor