[Angiotensin (1-7): a new link in the renin-angiotensin-aldosterone system (RAAS)].
The discovery of a new angiotensin-converting enzyme (ACE2) and studies of the biological activity of angiotensin (1-7) indicate the complexity of the functioning of the renin-angiotensinaldosterone system (RAAS). In this paper the activities of angiotensin (1-7) are summarized. Angiotensin (1-7) has vasodilating, antiproliferative, antifibrotic, and antithrombotic properties which antagonize the action of angiotensin II. This indicates new possibilities for the future use of these effects for better treatment efficiency of cardiovascular diseases.
Andrzejczak
Dariusz
D
Zakład Farmakodynamiki, Uniwersytet Medyczny w Łodzi, Poland.
D000803:Angiotensin I / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism*; D012084:Renin-Angiotensin System / Q000502:physiology*
D010446:Peptide Fragments; D000803:Angiotensin I; C118790:angiotensin I (1-7)