title: Antibacterial triterpenes from the threatened wood-decay fungus Fomitopsis rosea.
abstract: From a biologically active extract from the fungus Fomitopsis rosea, two new lanostane triterpenes were isolated, 3alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid C 1 and 3alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid 2, along with three known triterpenes, 3-5, and the epidioxy sterol derivative 6. The structures of the compounds were elucidated based on their spectral properties. All triterpenes demonstrated antibacterial activity against S. aureus but possessed no antiradical activity against DPPH radicals.
authors.affiliation: Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
authors.forename: Milena
authors.initials: M
authors.lastname: Popova
authors.forename: Boryana
authors.initials: B
authors.lastname: Trusheva
authors.forename: Melania
authors.initials: M
authors.lastname: Gyosheva
authors.forename: Iva
authors.initials: I
authors.lastname: Tsvetkova
authors.forename: Vassya
authors.initials: V
authors.lastname: Bankova
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002788:Cholesterol Esters / Q000302:isolation & purification* / Q000494:pharmacology; D055453:Coriolaceae / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C543231:3alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid; C543232:3alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid; D000900:Anti-Bacterial Agents; D002788:Cholesterol Esters; D014315:Triterpenes; C421424:epidioxysterol