[Prevalence of arterial hypertension in women with type 2 diabetes mellitus and diabetic foot syndrome].
The aim of the study was to evaluate prevalence of arterial hypertension (AH), efficiency of preceding therapy, and quality of life (QL) in 50 women with type 2 diabetes mellitus (DM) and diabetic foot syndrome (DFS) and 139 DM patients without DFS. The analysis included individual outpatient medical records, results of AH verification (WHO, RSC, 2004), parameters of carbohydrate and lipid metabolism, insulin resistance (IR) index, and QL data (SF-36 questionnaire). The patients were above 55 years of age. Active detection of AH revealed it in 98% of the patients with DFS and in 97% without it (p < 0.05). Detection of AH preceded diagnosis of LM. The lack of adequate IR correction (inefficient treatment with metformin, absence of thiazolidinedione therapy), irregular use of statins (in 4 and 8% of patients with and without DFS respectively, p = 0.541), inadequate antihypertensive therapy (absence of treatment at AP 130-139/80-89 mm Hg), rare application of ACE inhibitors, modification or withdrawal of prescribed therapy) resulted in decompensation of DM, dyslipidemia, poor control of AP, social and psychological problems in women with DM. Those having DFS suffered dyslipidemia, elevated AP, further progress of DFS manifestations and vascular complications, reduced QL in the absence of strict control of glycemia.
Onuchin
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Elsukova
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Onuchina
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D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D017719:Diabetic Foot / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D007333:Insulin Resistance / Q000502:physiology; D008055:Lipids / Q000097:blood; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
D000959:Antihypertensive Agents; D001786:Blood Glucose; D008055:Lipids