title: Highly enantioselective asymmetric autocatalysis using chiral ruthenium complex-ion-exchanged synthetic hectorite as a chiral initiator.
abstract: The synthetic hectorite containing intercalated chiral Delta- and Lambda-tris(1,10-phenanthroline)ruthenium(II) ions acts as a heterogeneous chiral catalyst in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde to afford, in combination with asymmetric autocatalytic amplification of enantiomeric excess, 5-pyrimidyl alkanol with high enantiomeric excess.
authors.affiliation: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
authors.forename: Tsuneomi
authors.initials: T
authors.lastname: Kawasaki
authors.forename: Toshiki
authors.initials: T
authors.lastname: Omine
authors.forename: Kenta
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hisako
authors.initials: H
authors.lastname: Sato
authors.forename: Akihiko
authors.initials: A
authors.lastname: Yamagishi
authors.forename: Kenso
authors.initials: K
authors.lastname: Soai
mesh_terms: D002384:Catalysis; D007474:Ion Exchange; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010618:Phenanthrolines / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D017640:Silicates / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D010618:Phenanthrolines; D017640:Silicates; C013547:hectorite; D012428:Ruthenium; C025205:1,10-phenanthroline