Cutaneous metastasis of breast carcinoma presenting as alopecia neoplastica.
Alopecia neoplastica is defined as hair loss secondary to a visceral malignancy that has metastasized to the scalp. We describe a woman with adenocarcinoma of the breast who developed alopecia neoplastica while receiving antineoplastic therapy. Alopecia neoplastica has been observed in 25 women. Breast cancer was the primary malignancy in 84% of patients with alopecia neoplastica. Other primary tumors whose metastases presented as neoplasm-related hair loss each occurred in one individual with gastric carcinoma, colon carcinoma, cervical carcinoma, and trophoblastic tumor.
Conner
Kelly B
KB
University of Texas-Houston Medical School; Department of Dermatology, University of Texas-Houston Medical School, USA.
Cohen
Philip R
PR
D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy; D000505:Alopecia / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy