[Time course of changes in lipid peroxidation parameters in patients with syphilis].
The prooxidative-antioxidative systems of plasma and blood corpuscles were evaluated in 151 patients with primary, secondary recent, secondary recurrent, and latent syphilis. The red blood cell levels of malonic dialdehyde, ceruloplasmin, and catalase were measured during the pathological process. The authors identified the following regularities: with active clinical manifestations of syphilis, there was a significant suppression of the blood antioxidative system and a substantial increase in the activity of the blood prooxidative system and blood corpuscles, with these parameters becoming normal after performed treatment. They also show it possible to use the tests of the blood prooxidative-antioxidative systems to evaluate the degree of the pathological process in patients with syphilis, as well as for prognostic purposes.
Nagoev
B S
BS
Bzhakhova
F K
FK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000097:blood*; D002570:Ceruloplasmin / Q000378:metabolism*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D008875:Middle Aged; D011379:Prognosis; D013587:Syphilis / Q000097:blood* / Q000175:diagnosis; D013997:Time Factors
D000975:Antioxidants; D008315:Malondialdehyde; D002374:Catalase; D002570:Ceruloplasmin