Getting a handle on Huntington's disease: silencing neurodegeneration.
La Spada
Albert R
AR
Department of Laboratory Medicine, and the Center for Neurogenetics & Neurotherapeutics, Room NW120, UWMC, 1959 Northeast Pacific Street, University of Washington, Seattle, Washington 98195, USA. laspada@u.washington.edu
D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000473:pathology; D000818:Animals; D001921:Brain / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D055785:Gene Knockdown Techniques; D020868:Gene Silencing; D006801:Humans; D006816:Huntington Disease / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D016376:Oligonucleotides, Antisense / Q000627:therapeutic use; D034622:RNA Interference; D051381:Rats
D016376:Oligonucleotides, Antisense; D002784:Cholesterol