title: A false positive F-FDG PET/CT scan caused by breast silicone injection.
abstract: We present here the case of a 40-year-old woman with a greater than 10 year prior history of bilateral breast silicone injection and saline bag implantation. Bilateral palpable breast nodules were observed, but the ultrasound scan was suboptimal and the magnetic resonance imaging showed no gadolinium-enhanced tumor. The (18)F-FDG PET/CT scan showed a hypermetabolic nodule in the left breast with a 30% increase of (18)F-FDG uptake on the delayed imaging, and this mimicked breast cancer. She underwent a left partial mastectomy and the pathology demonstrated a siliconoma.
authors.affiliation: Department of Nuclear Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.
authors.forename: Chao-Jung
authors.initials: CJ
authors.lastname: Chen
authors.forename: Bi-Fang
authors.initials: BF
authors.lastname: Lee
authors.forename: Wei-Jen
authors.initials: WJ
authors.lastname: Yao
authors.forename: Pei-Shan
authors.initials: PS
authors.lastname: Wu
authors.forename: Wen-Chung
authors.initials: WC
authors.lastname: Chen
authors.forename: Shu-Lin
authors.initials: SL
authors.lastname: Peng
authors.forename: Nan-Tsing
authors.initials: NT
authors.lastname: Chiu
mesh_terms: D000328:Adult; D018427:Breast Implants / Q000009:adverse effects; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D015745:Granuloma, Foreign-Body / Q000175:diagnosis*; D006801:Humans; D007267:Injections; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D012828:Silicones; D019788:Fluorodeoxyglucose F18