The autonomic phenotype of rumination.
Recent studies suggest that ruminative thoughts may be mediators of the prolonged physiological effects of stress. We hypothesized that autonomic dysregulation plays a role in the relation between rumination and health. Rumination was induced by an anger-recall task in 45 healthy subjects. Heart rate variability (HRV), baroreflex sensitivity (BRS), and baroreflex effectiveness index (BEI) change scores were evaluated to obtain the autonomic phenotype of rumination. Personality traits and endothelial activation were examined for their relation to autonomic responses during rumination. Degree of endothelial activation was assessed by circulating soluble intercellular adhesion molecule-1 (sICAM-1). Vagal withdrawal during rumination was greater for women than men. Larger decreases in the high frequency component of HRV were associated with higher levels of anger-in, depression, and sICAM-1 levels. BRS reactivity was negatively related to trait anxiety. BEI reactivity was positively related to anger-in, hostility, anxiety, and depression. Lower BEI and BRS recovery were associated with lower social desirability and higher anger-out, anxiety, and depression. Findings suggest that the autonomic dysregulation that characterizes rumination plays a role in the relationships between personality and cardiovascular health.
Ottaviani
Cristina
C
Department of Psychology, University of Bologna, viale Berti Pichat, 5, 40127 Bologna, Italy. cristina.ottaviani@unibo.it
Shapiro
David
D
Davydov
Dmitry M
DM
Goldstein
Iris B
IB
Mills
Paul J
PJ
D000178:Acrylamides / Q000097:blood; D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D017704:Baroreflex / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008875:Middle Aged; D017008:Negotiating; D010551:Personality / Q000502:physiology*; D010555:Personality Inventory; D010641:Phenotype; D020127:Recovery of Function; D012119:Respiration; D012737:Sex Factors; D013315:Stress, Psychological / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D015091:beta-Alanine / Q000031:analogs & derivatives / Q000097:blood
C531963:2-(2,6-dichloro-4-((3-furan-2-ylacryloylamino)methyl)benzoylamino)-3-((thiazolidine-4-carbonyl)amino)propionic acid; D000178:Acrylamides; D015091:beta-Alanine