title: Which factors hinder the decision of Polish HIV-positive patients to take up antiretroviral therapy?
abstract: The implementation of highly active antiretroviral therapy (HAART) in 1996 has significantly reduced mortality and morbidity for HIV-positive patients worldwide. However not all eligible persons start HAART. To identify reasons for therapy refusal by HIV-positive persons we performed a questionnaire study. The investigation was conducted among 321 HIV-positive individuals and focused on the decision to take up antiretroviral treatment. Out of 71 untreated patients, 34 (47.9%) admitted that in their case the therapy was not indicated, whereas 20 (28.3%) were afraid of potential side effects that might change their appearance, e.g. face lipoatrophy. Only the treated patients had been prepared to take up therapy, although 17 patients (6.0%) had not received any explanation of the therapy principles, aims or necessity to comply with medication regime. The therapy is generally not discussed with the patients for whom it is not currently indicated, which may contribute to the fixation of fears and prejudices. Doctors who treat HIV-positive patients should be aware of the prejudices and fears their patients have towards antiretroviral therapy in order to react properly and by means of the available antiretroviral drugs help prolong life and improve its quality.
authors.affiliation: Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland. dszadkowska@bsk.vectranet.pl
authors.forename: D
authors.initials: D
authors.lastname: Rogowska-Szadkowska
authors.forename: S
authors.initials: S
authors.lastname: Chlabicz
authors.forename: M A
authors.initials: MA
authors.lastname: Oltarzewska
authors.forename: J
authors.initials: J
authors.lastname: Sawicka-Powierza
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000523:psychology*; D001294:Attitude to Health; D003657:Decision Making; D005239:Fear; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010817:Physician-Patient Relations; D011044:Poland; D011287:Prejudice; D012307:Risk Factors; D016312:Treatment Refusal / Q000523:psychology*; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents