title: Epidemiology of nodular goiter in South Georgia and selection of some diagnostic criteria from the view point of prevention.
abstract: Mountainous regions of Georgia have been long known as a center of goiter endemia. Study of thyroid gland diseases in this contingent of population represents a key target. The object of the conducted examinations was study of epidemiology of goiter in the South Georgia. According to the results of our study high index of spreading endemic goiter in the population of the South Georgia is conditioned by iodine-deficiency. In addition, the factor providing spreading of thyroid gland pathology in the country is improper feeding. At the same time we aimed to study in these populations such diagnostic indices of various pathologies of thyroid gland as carcinoma - embryonic antigen CEA, which has been less studied. There is scanty information on these markers during thyroid gland pathology and in populations of Georgia it is absent at all. Due to the fact that the mentioned marker makes possible to conduct monitoring of the disease, we consider the study of its infomativity to be important during various forms of nodular goiter. For comparison of the results study of oncomarker REA was conducted in group of healthy individuals and non-nodular goiter. On the base of obtained data it can be supposed that study of oncomarker CEA is informative for diagnosis of various forms of nodular goiter as additional criteria, especially in case of obscure or not conducted morphological diagnosis.
authors.affiliation: Georgian State Medical University, Clinical Laboratory Department, Georgia.
authors.forename: K
authors.initials: K
authors.lastname: Nakaidze
authors.forename: N
authors.initials: N
authors.lastname: Gogokhia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002391:Catchment Area, Health; D005260:Female; D005846:Georgia (Republic) / Q000453:epidemiology; D006044:Goiter, Nodular / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D000091402:Prohibitins; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D014463:Ultrasonography; D055815:Young Adult