title: Accurate nano-injection system for capillary gas chromatography.
abstract: The first version of nano-injection device for capillary gas chromatography (cGC) based on inkjet microchip was developed. The nano-injector could accurately control the injection volume in nano-liter, even pico-liter range. Its configuration and mechanism were discussed in detail. Adopting photolithography and plasma etching technology, we firstly fabricated the inkjet microchip and stuck to a piezoelectric device to eject droplets. Then, a special feedback tube was added to make it function as a nano-injector for cGC, which was an important design to compensate pressure difference between the evaporation chamber of cGC and the sample extrusion chamber of inkjet microchip. The injected volume can be precisely controlled by the number of injected droplets. Excellent precision (RSDs were below 10.0%, n=5) was observed for the injection of ethanol at elevated pressure. Minimum injection volume was about 1.25nL at present. Additionally, good repeatability of the calibration curves for the hydrocarbons ethanolic solution (the RSDs of all components were below 5.30%, n=5) confirmed its feasibility in quantitative analysis regardless of concentration. These results suggested that it can be an accurate nano-injector for cGC.
authors.affiliation: Department of Applied Chemistry, Urban Environmental Sciences, Tokyo Metropolitan University, Hachioji, Tokyo, Japan. zhluse@gmail.com
authors.forename: Hu-Lie
authors.initials: HL
authors.lastname: Zeng
authors.forename: Nobuko
authors.initials: N
authors.lastname: Seino
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Nakagama
authors.forename: Yubun
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Hazumu
authors.initials: H
authors.lastname: Nagano
authors.forename: Katsumi
authors.initials: K
authors.lastname: Uchiyama
mesh_terms: D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D000431:Ethanol / Q000737:chemistry; D006838:Hydrocarbons / Q000032:analysis; D016014:Linear Models; D036103:Nanotechnology / Q000295:instrumentation*; D011312:Pressure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D006838:Hydrocarbons; D000431:Ethanol