title: [Sarcoidosis-like granulomatosis revealing a tertiary syphilis].
abstract: Numerous disorders can cause a systemic granulomatosis. We report a patient who presented a biopsy proven granulomatous skin eruption, fever, and atypical thoracic pain. Electrocardiogram showed a first-degree atrioventricular heart bloc. During follow-up he developed a panuveitis and oral corticosteroids were started. A diagnosis of systemic sarcoidosis was considered. Because of unfavourable ophthalmologic outcome, investigations were enlarged and revealed a highly positive serology for syphilis and VDRL both in serum and cerebrospinal fluid. Clinical outcome with penicillin G therapy was favorable. This observation reminds us the clinical polymorphism of syphilis, which can be presented as a systemic granulomatosis.
authors.affiliation: Service de médecine interne, CHU de Nantes, place Alexis-Ricordeau, 44093 Nantes cedex, France. baptiste.hervier@chu-nantes.fr
authors.forename: B
authors.initials: B
authors.lastname: Hervier
authors.forename: H
authors.initials: H
authors.lastname: Wastiaux
authors.forename: T
authors.initials: T
authors.lastname: Freour
authors.forename: A
authors.initials: A
authors.lastname: Masseau
authors.forename: S
authors.initials: S
authors.lastname: Corvec
authors.forename: T
authors.initials: T
authors.lastname: Armingeat
authors.forename: M
authors.initials: M
authors.lastname: Hamidou
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D054537:Atrioventricular Block / Q000175:diagnosis / Q000209:etiology; D001706:Biopsy; D004562:Electrocardiography; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D015864:Panuveitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D010400:Penicillin G / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology; D013587:Syphilis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D013588:Syphilis Serodiagnosis; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D010400:Penicillin G