Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest.
BACKGROUND
The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated.


RESULTS
Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient.


CONCLUSIONS
OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary.
Takagi
Yusuke
Y
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yasuda
Satoshi
S
Takahashi
Jun
J
Takeda
Morihiko
M
Nakayama
Masaharu
M
Ito
Kenta
K
Hirose
Masanori
M
Wakayama
Yuji
Y
Fukuda
Koji
K
Shimokawa
Hiroaki
H
D000328:Adult; D003329:Coronary Vasospasm; D017147:Defibrillators, Implantable; D005260:Female; D006323:Heart Arrest / Q000401:mortality* / Q000503:physiopathology*; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D014693:Ventricular Fibrillation