title: The estimated risk of miscarriage should be corrected for induced abortion rates.
abstract: OBJECTIVE
  We wanted to study to what extent induced abortion rates influence the age-dependent estimates of miscarriage risk.
  
  
  METHODS
  Register-based study.
  
  
  METHODS
  Linkage between hospital records and the Norwegian Population Registry.
  
  
  METHODS
  Included were all women 15-49 years of age in Oslo, Norway, who were pregnant during the three-year study period, 27,932 women.
  
  
  METHODS
  We estimated proportions with miscarriage according to maternal age with and without inclusion of women with induced abortion in the denominator.
  
  
  METHODS
  Proportions with miscarriage in each age group and odds ratios of miscarriage, with age group 25-29 years as the reference.
  
  
  RESULTS
  When only women with pregnancies intended to term were included in the denominator, 9.4% of the women were estimated to have miscarriage as the only reproductive event during the three-year period and 6.8% had both miscarriage and delivery. The corresponding figures when also women with induced abortions were included in the denominator, were 7.0 and 5.0%. When taking induced abortion into account, the reduction in estimated proportion with miscarriage during the study period was greatest in the age groups with the highest induced abortion rates, women 15-19 years old (from 22.8 to 6.4%) and women 45-49 years old (from 57.9 to 41.0%).
  
  
  CONCLUSIONS
  Estimates of age-dependent risk of miscarriage may be strongly influenced by induced abortion rates.
authors.affiliation: Department of Obstetrics and Gynaecology, Akershus University Hospital and Medical Faculty, University of Oslo, Lørenskog, Norway. anne.eskild@medisin.uio.no
authors.forename: Anne
authors.initials: A
authors.lastname: Eskild
authors.forename: Lars J
authors.initials: LJ
authors.lastname: Vatten
authors.forename: Britt-Ingjerd
authors.initials: BI
authors.lastname: Nesheim
authors.forename: Siri
authors.initials: S
authors.lastname: Vangen
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects* / Q000706:statistics & numerical data*; D000022:Abortion, Spontaneous / Q000453:epidemiology* / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008423:Maternal Age; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D016017:Odds Ratio; D011247:Pregnancy; D012042:Registries; D012307:Risk Factors; D055815:Young Adult