title: Retro-orbital granulocytic sarcoma: case report.
abstract: Granulocytic sarcomas (chloromas) are rare extra-medullary tumors arising from primitive granulocytic cells. The term "chloroma" is derived from the Greek word chloros (green), and it refers to the frequently greenish color of the tumor, which is due to the presence and oxidation of the myeloperoxidase enzyme. These tumors can arise de novo or can be associated with other myeloid disorders, such as acute or chronic myeloid leukemia, myeloproliferative or myelodysplastic conditions. Presentation can occur prior to, in association with the underlying myeloid disorder, or upon relapse. The location of the tumor can vary: sub-periosteal bone, skull, pelvis, ribs, sternum or lymph nodes. We report the case of a 58-year-old man who presented right exophthalmos and ophthalmoplegy with computerized tomography (CT) evidence of a retro-orbital mass, which histology confirmed to be a granulocytic sarcoma.
authors.affiliation: Dipartimento di Diagnostica per Immagini, Imaging molecolare, Radiologia Interventistica e Radioterapia, Policlinico Universitario "Tor Vergata", Rome, Italy. Alessandro.dimarzo@tiscali.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Marzo
authors.forename: Giampiero
authors.initials: G
authors.lastname: Parca
authors.forename: Gianluca
authors.initials: G
authors.lastname: Ingrosso
authors.forename: Cesare
authors.initials: C
authors.lastname: Giubilei
authors.forename: Michele
authors.initials: M
authors.lastname: Battista
authors.forename: Michaela
authors.initials: M
authors.lastname: Benassi
authors.forename: Rosaria
authors.initials: R
authors.lastname: Barbarino
authors.forename: Federica
authors.initials: F
authors.lastname: Proietti
authors.forename: Sara
authors.initials: S
authors.lastname: Costantini
authors.forename: Luana
authors.initials: L
authors.lastname: Di Murro
authors.forename: Rebeca
authors.initials: R
authors.lastname: Nicolais
authors.forename: Federico
authors.initials: F
authors.lastname: Santarelli
authors.forename: Riccardo
authors.initials: R
authors.lastname: Santoni
mesh_terms: D005094:Exophthalmos / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D023981:Sarcoma, Myeloid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed