Scavenging capacities of some thiazolyl thiazolidine-2,4-dione compounds on superoxide radical, hydroxyl radical, and DPPH radical.
The scavenging effects of eighteen thiazolyl thiazolidine-2,4-dione compounds (TTCs) on superoxide radical ( (-) (*) ) (2), hydroxyl radical HO(*), and 1,1-diphenyl-2-picrylhydrazyl (DPPH(*)) radical were evaluated by the chemiluminescence technique, electron spin resonance spectrometry (ESR) and visible spectrophotometry, respectively. The examined compounds were shown to have 27-59% ( (-) (*) ) (2) scavenging ability, 19-69% HO(*) scavenging activity and 2-32% DPPH(*) scavenging ability. This property of the tested compound seems to be important in the prevention of various diseases of free radicals etiology.
Kruk
Irena
I
Institute of Physics, Szczecin University of Technology, Al. Piastów 48/49, 70-311 Szczecin, Poland.
Bozdağ-Dündar
Oya
O
Ceylan-Unlüsoy
Meltem
M
Ertan
Rahmiye
R
Aboul-Enein
Hassan Y
HY
Michalska
Teresa
T
D001713:Biphenyl Compounds / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D016166:Free Radical Scavengers / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry*; D008163:Luminescent Measurements; D015394:Molecular Structure; D010851:Picrates / Q000737:chemistry*; D013053:Spectrophotometry; D013481:Superoxides / Q000737:chemistry*; D045162:Thiazolidinediones / Q000737:chemistry*
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010851:Picrates; D045162:Thiazolidinediones; C500090:thiazolidine-2,4-dione; D013481:Superoxides; D017665:Hydroxyl Radical; C004931:1,1-diphenyl-2-picrylhydrazyl