Evidence for qnrB1 and aac(6')-Ib-cr in CTX-M-15-producing uropathogenic Enterobacteriaceae in an Italian teaching hospital.
In this work, we report the spread of CTX-M-producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6')-Ib-cr, qnrB1, and bla(CTX-M-15) resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient.
Perilli
Mariagrazia
M
Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi dell'Aquila, Italy. perilli@univaq.it
Forcella
Chiara
C
Celenza
Giuseppe
G
Frascaria
Patrizia
P
Segatore
Bernardetta
B
Pellegrini
Cristina
C
Amicosante
Gianfranco
G
D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D023061:Gene Order; D005798:Genes, Bacterial; D006784:Hospitals, Teaching; D006801:Humans; D007558:Italy; D014552:Urinary Tract Infections / Q000382:microbiology*; D001618:beta-Lactamases / Q000096:biosynthesis; D047090:beta-Lactams / Q000494:pharmacology
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D002939:Ciprofloxacin; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases