Efficient intramolecular hydroalkoxylation/cyclization of unactivated alkenols mediated by lanthanide triflate ionic liquids.
Lanthanide triflates, Ln(OTf)(3), serve as efficient catalysts for the intramolecular hydroalkoxylation (HO)/cyclization of primary/secondary and aliphatic/aromatic hydroxyalkenes in room temperature ionic liquids (RTILs). Cyclizations are effective in the formation of five- and six-membered oxygen heterocycles with Markovnikov-type selectivity. Reaction rates exhibit first-order dependence on [Ln(3+)] and [substrate].
Dzudza
Alma
A
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.
Marks
Tobin J
TJ
D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D052578:Ionic Liquids / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure
D000438:Alcohols; D052578:Ionic Liquids; D028581:Lanthanoid Series Elements; D008698:Mesylates