[Recurrent multi-focal cerebral stroke complicating Libman-Sacks endocarditis in a young woman with systemic lupus erythromatosus].
Systemic lupus erythromatosus is often associated with an antiphospholipid syndrome (APS). A high prevalence of valvular heart disease in APS leads to increased risk of embolic events, particularly cerebrovascular. We present a patient with cerebral infarction, with positive lupus anticoagulant, anticardiolipin antibodies and factor V Leiden mutation. Echocardiographic examination revealed mitral valve anterior leaflet thickening and verrucous vegetations consistent with Libman-Sacks endocarditis, which is commonly associated with APS.
Jedliński
Ireneusz
I
Oddział Kardiologiczny, Szpital im. J. Strusia, ul. Szkolna 8/12, 61-833 Poznań. irejed@wp.pl
Duszyńska
Małgorzata
M
Lehmann-Kopydłowska
Agata
A
Jamrozek-Jedlińska
Maria
M
Poprawski
Kajetan
K
Zawilska
Krystyna
K
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis; D002544:Cerebral Infarction / Q000209:etiology; D015150:Echocardiography, Doppler; D004696:Endocarditis / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D012008:Recurrence