title: Efficient intramolecular hydroalkoxylation/cyclization of unactivated alkenols mediated by lanthanide triflate ionic liquids.
abstract: Lanthanide triflates, Ln(OTf)(3), serve as efficient catalysts for the intramolecular hydroalkoxylation (HO)/cyclization of primary/secondary and aliphatic/aromatic hydroxyalkenes in room temperature ionic liquids (RTILs). Cyclizations are effective in the formation of five- and six-membered oxygen heterocycles with Markovnikov-type selectivity. Reaction rates exhibit first-order dependence on [Ln(3+)] and [substrate].
authors.affiliation: Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.
authors.forename: Alma
authors.initials: A
authors.lastname: Dzudza
authors.forename: Tobin J
authors.initials: TJ
authors.lastname: Marks
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D052578:Ionic Liquids / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000438:Alcohols; D052578:Ionic Liquids; D028581:Lanthanoid Series Elements; D008698:Mesylates