Triplet pregnancy and successful twin delivery in a patient with congenital cervical atresia who underwent transmyometrial embryo transfer and multifetal pregnancy reduction.
OBJECTIVE
To report an unusual case of congenital cervical atresia and tubal factor infertility, achieving triplet pregnancy through transmyometrial embryo transfer (ET) resulting in the delivery of healthy twins after multifetal pregnancy reduction (MFPR).


METHODS
Case report and literature review.


METHODS
University hospital.


METHODS
Controlled ovarian hyperstimulation, oocyte retrieval, in vitro fertilization, transmyometrial ET, MFPR procedure for triplet pregnancy.


METHODS
A 33-year-old patient with endometriosis-associated and tubal factor infertility who underwent uterovaginal canalization surgery for congenital cervical atresia 9 years ago.


METHODS
Successful delivery after transmyometrial ET followed by MFPR.


RESULTS
A total of three IVF cycles and four procedures of transmyometrial ET were performed. In the third cycle a triplet pregnancy was achieved. MFPR was performed 35 days after embryos transfer, two healthy babies delivered at 31 weeks gestation.


CONCLUSIONS
With aggressive therapy, successful pregnancy is possible in similar patients.
Xu
Chenming
C
Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China.
Xu
Jian
J
Gao
Huijuan
H
Huang
Hefeng
H
D000328:Adult; D002584:Cervix Uteri / Q000002:abnormalities*; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011247:Pregnancy; D018607:Pregnancy Reduction, Multifetal; D014310:Triplets
D018997:Chorionic Gonadotropin, beta Subunit, Human