title: M-mode photoacoustic particle flow imaging.
abstract: Recently, there has been growing interest in the development of photoacoustic flow measuring methods aimed to study microvascular blood flow in biological tissue. Here, we describe the M-mode photoacoustic particle flow imaging, using an optical resolution photoacoustic microscope equipped with a high-repetition-rate pulsed dye laser. We studied the flow of a diluted dyed particle suspension in a small tube embedded in a nonscattering medium as well as in a scattering medium simulating biological tissue. Potentially, the method can be applied to detect the flow speed of single red blood cells in a capillary.
authors.affiliation: Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
authors.forename: Hui
authors.initials: H
authors.lastname: Fang
authors.forename: Lihong V
authors.initials: LV
authors.lastname: Wang
mesh_terms: D000162:Acoustics; D001783:Blood Flow Velocity; D018056:Hemorheology; D007834:Lasers; D008833:Microcirculation / Q000502:physiology; D010316:Particle Size; D018462:Photobiology; D012212:Rheology / Q000706:statistics & numerical data; D012542:Scattering, Radiation; D014465:Ultrasonics