title: Ovarian cancer: pathology, biology, and disease models.
abstract: Epithelial ovarian cancer, which comprises several histologic types and grades, is the most lethal cancer among women in the United States. In this review, we summarize recent progress in understanding the pathology and biology of this disease and in development of models for preclinical research. Our new understanding of this disease suggests new targets for therapeutic intervention and novel markers for early detection of disease.
authors.affiliation: Department of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77005-4095, USA.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Rosen
authors.forename: Gong
authors.initials: G
authors.lastname: Yang
authors.forename: Guangzhi
authors.initials: G
authors.lastname: Liu
authors.forename: Imelda
authors.initials: I
authors.lastname: Mercado-Uribe
authors.forename: Bin
authors.initials: B
authors.lastname: Chang
authors.forename: Xue Sherry
authors.initials: XS
authors.lastname: Xiao
authors.forename: Jingfang
authors.initials: J
authors.lastname: Zheng
authors.forename: Feng-Xia
authors.initials: FX
authors.lastname: Xue
authors.forename: Jinsong
authors.initials: J
authors.lastname: Liu
mesh_terms: D005260:Female; D005801:Genes, Homeobox; D006801:Humans; D010051:Ovarian Neoplasms / Q000145:classification / Q000235:genetics / Q000473:pathology*