title: Giant angiolymphoid hyperplasia with eosinophilia on the chest.
abstract: Angiolymphoid hyperplasia with eosinophilia is a rare vascular proliferation characterized by single or multiple purplish, brownish papules and subcutaneous nodules, sometimes associated with pain or pruritus. This rare benign process occurs with a female predominance. Approximately 85% of the lesions occur in the skin of the head and neck; most of them are around the ear or on the forehead or scalp. Whether angiolymphoid hyperplasia with eosinophilia represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, the etiology remains unclear. Histopathologically, the lesions consist of a proliferation of blood vessels of variable size lined by large epithelioid endothelial cells and a variable inflammatory infiltrate of lymphocytes and eosinophils, sometimes with lymphoid follicle formation. The lesion is benign but may be persistent and is difficult to eradicate. We report on a case of a 58-year-old Caucasian man who presented a purplish pink dome-shaped tumor of size up to 8 cm in diameter located on the chest. We emphasize this case considering the unusual dimensions of the lesion (8 cm diameter) and the atypical location on the chest.
authors.affiliation: Department of Dermatology, Hospital dos Capuchos, Lisbon, Portugal. felicidade.trindade@gmail.com
authors.forename: Felicidade
authors.initials: F
authors.lastname: Trindade
authors.forename: Rosario
authors.initials: R
authors.lastname: Haro
authors.forename: Luis
authors.initials: L
authors.lastname: Requena
mesh_terms: D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013909:Thorax / Q000473:pathology*