title: Is steroid therapy enough to reverse complete atrioventricular block after percutaneous perimembranous ventricular septal defect closure?
abstract: Due to the close proximity of the perimembranous ventricular septal defect to the conduction system, complete atrioventricular block may occur after transcatheter closure in around 1-5% of cases. Some authors reported on successful use of steroids and aspirin in reversing complete atrioventricular heart block early after transcatheter closure of perimembranous ventricular septal defect using the Amplatzer membranous ventricular septal defect occluder. In this paper, we report a case of reappearance of complete atrioventricular block requiring a definitive pacemaker implantation after an initial successful reversal using both steroids and aspirin.
authors.affiliation: Pediatric Cardiology and GUCH unit, Policlinico San Donato IRCCS, San Donato Milanese, Italy. gianfra.but@lycos.com
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Butera
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Gaio
authors.forename: Mario
authors.initials: M
authors.lastname: Carminati
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use; D054537:Atrioventricular Block / Q000209:etiology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects* / Q000295:instrumentation; D002304:Cardiac Pacing, Artificial; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D004359:Drug Therapy, Combination; D015716:Electrocardiography, Ambulatory; D006345:Heart Septal Defects, Ventricular / Q000628:therapy*; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008297:Male; D010138:Pacemaker, Artificial; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D013256:Steroids / Q000627:therapeutic use*; D017211:Treatment Failure
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids; D011239:Prednisolone; D001241:Aspirin; D006854:Hydrocortisone