[Progresses on thyroid hormone responsive spot 14 (THRSP) gene in chickens and ducks].
Thyroid hormone responsive spot 14 (THRSP), expressed in lipogenic tissues, is suggested as a transcription factor to regulate gene expression of rate-limiting enzymes in lipogenesis. Two THRSP isoforms, THRSPa and THRSPb, were detected at cDNA levels in chickens and ducks. Chicken THRSPa was speculated to be associated with growth development and lipid metabolism because of significant correlation between the indels in the coding region of THRSPalpha and growth, as well as abdominal fat traits of chickens. The differences of THRSP structure and expression between chickens and ducks were reviewed. Furthermore, polymorphism and genetic effects of THRSP gene in chickens and ducks were analyzed.
Zhan
Kai
K
Institute of Animal Husbandry and Veterinary, Agricultural Academy of Anhui Province, Hefei 230031, China. zhankai633@126.com
Yang
Ning
N
Xu
Gui-Yun
GY
Xu
Yue-Ying
YY
Zhao
Rui-Hong
RH
D000818:Animals; D002645:Chickens; D004372:Ducks; D020869:Gene Expression Profiling; D050356:Lipid Metabolism / Q000235:genetics*; D050155:Lipogenesis / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D020033:Protein Isoforms / Q000502:physiology*; D013963:Thyroid Hormones / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology*
D020033:Protein Isoforms; D013963:Thyroid Hormones; D014157:Transcription Factors