title: Solid-phase based total synthesis of Jasplakinolide by ring-closing metathesis.
abstract: The study of classical ring-closing metathesis and relay ring-closing metathesis in a total synthesis of Jasplakinolide and its desbromo analog is described.
authors.affiliation: Technische Universität Dortmund, Fakultät Chemie, Otto-Hahn-Str. 6, D-44227, Dortmund, Germany.
authors.forename: René
authors.initials: R
authors.lastname: Tannert
authors.forename: Tai-Shan
authors.initials: TS
authors.lastname: Hu
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Arndt
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D047630:Depsipeptides; C540619:desbromo jasplakinolide; C057531:jasplakinolide