Blockade of ICAM-1: a novel way of vasculitis treatment.
Vasculitis is becoming more common worldwide, but there is no effective therapeutic method towards this series of disease till now. Intercellular adhesion molecule (ICAM)-1 is one of an important cell adhesion molecules (CAMs) family glycoprotein that plays pivotal role in inflammation process and participates in vasculitis. Blockade of ICAM-1 has been witnessed with its satisfactory effect on inflammatory disease treatment. Therefore, this method may be considered as a novel way towards treatment of vasculitis.
Xu
Youhua
Y
Department of Pharmacology, Nanjing Medical University, PR China.
Li
Shengnan
S
D002448:Cell Adhesion; D002465:Cell Movement; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism*; D014657:Vasculitis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology
D018799:Intercellular Adhesion Molecule-1