title: Three-dimensional echocardiography-guided repair of severe paravalvular regurgitation in a bioprosthetic and mechanical mitral valve.
abstract: Severe paravalvular mitral regurgitation is a rare but important complication of mitral valve replacement, often producing symptoms associated with refractory heart failure or haemolysis. Explantation and replacement of the prosthesis are required in some patients but may not be possible in patients with high risk of morbidity or mortality with re-operation. We present two patients with symptomatic paravalvular mitral regurgitation who were deemed too high risk for re-operation because of multiple previous sternotomies and comorbidities. Percutaneous three-dimensional (3D) echocardiography-guided repair with septal occluder devices was undertaken in the first case of a paravalvular defect adjacent to a mitral bioprosthesis and in the second case adjacent to a mechanical mitral prosthesis. Both cases illustrate the advantage 3D echocardiography provides by allowing en-face views of the paravalvular leak and unique views of the catheter and device placement. The second case further demonstrates the novel use of full volume colour to define the extent of the regurgitant jet and provides information critical to device sizing and placement.
authors.affiliation: Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard University, 55 Fruit Street, Boston, MA, USA. amerjohri@gmail.com
authors.forename: Amer M
authors.initials: AM
authors.lastname: Johri
authors.forename: Kibar
authors.initials: K
authors.lastname: Yared
authors.forename: Ronen
authors.initials: R
authors.lastname: Durst
authors.forename: Roberto J
authors.initials: RJ
authors.lastname: Cubeddu
authors.forename: Igor F
authors.initials: IF
authors.lastname: Palacios
authors.forename: Michael H
authors.initials: MH
authors.lastname: Picard
authors.forename: Jonathan
authors.initials: J
authors.lastname: Passeri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001705:Bioprosthesis; D018618:Echocardiography, Doppler, Color; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000601:surgery; D018084:Ultrasonography, Interventional