[The role of the interferon system in pathogenesis of endothelial dysfunction in patients with metabolic syndrome].
We have studied the serum interferon activity and its relation to the endothelial dysfunction. Atherosclerosis development in patients with metabolic syndrome is followed by significant increase in interferon activity. Close relation presents between activity of the serum interferon and indexes of structural and functional changes of arterial vessels compromised with atherosclerosis process.
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D000328:Adult; D050197:Atherosclerosis / Q000097:blood / Q000209:etiology*; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007372:Interferons / Q000097:blood*; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D008875:Middle Aged
D001786:Blood Glucose; D008055:Lipids; D007372:Interferons