title: Initial experience with a new laparoscopic ultrasound probe for guided biopsy in the staging of upper gastrointestinal cancer.
abstract: BACKGROUND
  Until recently, laparoscopic ultrasound (LUS)-guided biopsy has been difficult with the available probes on the market. This study aimed to present a new laparoscopic ultrasound probe (Hitachi, EUP-OL531) for guided biopsy and describe its impact on the clinical outcome for patients with upper gastrointestinal (UGI) cancer.
  
  
  METHODS
  Patients referred with confirmed UGI cancer from June 2003 to December 2006 were included in the study. After a standard workup including computed tomography, endoscopic ultrasound, and ultrasound of the neck, operable patients underwent LUS with or without fine-needle aspiration (FNA).
  
  
  RESULTS
  From a total of 175 patients, 19 (11%) underwent LUS-guided FNA after a significant lesion was found. The LUS-guided FNA confirmed distant metastasis in 14 of the 19 patients and changed the clinical management for these 14 patients (8%). There were no adverse events due to LUS or LUS-guided FNA.
  
  
  CONCLUSIONS
  The current results with the new LUS probe for guided FNA are encouraging in terms of its diagnostic ability, safety, and ease of use.
authors.affiliation: Gentofte Hospital, Copenhagen, Denmark. hazim@dadlnet.dk
authors.forename: Hazem
authors.initials: H
authors.lastname: Hassan
authors.forename: Peter
authors.initials: P
authors.lastname: Vilmann
authors.forename: Vijay
authors.initials: V
authors.lastname: Sharma
authors.forename: Jakob
authors.initials: J
authors.lastname: Holm
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle / Q000379:methods*; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D003131:Combined Modality Therapy; D004867:Equipment Design; D004938:Esophageal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D004940:Esophageal Stenosis / Q000000981:diagnostic imaging / Q000209:etiology; D004943:Esophagogastric Junction / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009339:Needles; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging; D009367:Neoplasm Staging / Q000379:methods*; D010166:Palliative Care; D010865:Pilot Projects; D011446:Prospective Studies; D015607:Stents; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D018084:Ultrasonography, Interventional / Q000295:instrumentation* / Q000379:methods
chemical_list: D000970:Antineoplastic Agents