title: Prevalence of complicated gastroesophageal reflux disease and Barrett's esophagus among racial groups in a multi-center consortium.
abstract: OBJECTIVE
  The Clinical Outcomes Research Initiative database was used to evaluate ethnic trends in complicated reflux disease and suspected Barrett's esophagus among various racial groups.
  
  
  METHODS
  Endoscopic findings for procedures performed January 2000-December 2005 for any indication and for reflux-related indications were reviewed by racial group.
  
  
  RESULTS
  Of 280,075 procedures examined, Hispanics were the most likely to have esophagitis (Hispanic 19.6%, white 17.3%, black 15.8%, Asian/Pacific Islander 9.5%, P-value<0.0001), and white subjects were most likely to have suspected BE (white 5.0%, Hispanic 2.9%, Asian/Pacific Islander 1.8%, black 1.5%, P-value<0.0001). Endoscopies performed for reflux-related indications had similar trends for esophagitis and esophageal stricture. Among reflux/Barrett's screening procedures adjusted for age and gender, Hispanics were most likely to have esophagitis (OR=1.28, P-value<0.0001) compared to Caucasians.
  
  
  CONCLUSIONS
  Our results demonstrate an association of suspected Barrett's esophagus and stricture with white patients and esophagitis with Hispanic patients. These findings need to be followed-up with further study.
authors.affiliation: Department of Gastroenterology, Oregon Health and Science University, 3303 SW Bond Avenue, CHH6D, Portland, OR 97239, USA. wangamy@ohsu.edu
authors.forename: Amy
authors.initials: A
authors.lastname: Wang
authors.forename: Nora C
authors.initials: NC
authors.lastname: Mattek
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Holub
authors.forename: David A
authors.initials: DA
authors.lastname: Lieberman
authors.forename: Glenn M
authors.initials: GM
authors.lastname: Eisen
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D044466:Asian People / Q000706:statistics & numerical data; D001471:Barrett Esophagus / Q000208:ethnology* / Q000473:pathology; D004940:Esophageal Stenosis / Q000208:ethnology* / Q000209:etiology / Q000473:pathology; D004942:Esophagitis, Peptic / Q000208:ethnology* / Q000209:etiology / Q000473:pathology; D004945:Esophagoscopy; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000208:ethnology* / Q000473:pathology; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D044468:Native Hawaiian or Pacific Islander / Q000706:statistics & numerical data; D016017:Odds Ratio; D015995:Prevalence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D014481:United States; D044465:White People / Q000706:statistics & numerical data