title: Determination of triclosan, triclocarban and methyl-triclosan in aqueous samples by dispersive liquid-liquid microextraction combined with rapid liquid chromatography.
abstract: In this study, dispersive liquid-liquid microextraction (DLLME) combined with ultra-high-pressure liquid chromatography (UHPLC)-tunable ultraviolet detection (TUV), has been developed for pre-concentration and determination of triclosan (TCS), triclocarban (TCC) and methyl-triclosan (M-TCS) in aqueous samples. The key factors, including the kind and volume of extraction solvent and dispersive solvent, extraction time, salt effect and pH, which probably affect the extraction efficiencies were examined and optimized. Under the optimum conditions, linearity of the method was observed in the range of 0.0500-100 microg L(-1) for TCS, 0.0250-50.0 microg L(-1) for TCC, and 0.500-100 microgL(-1) for M-TCS, respectively, with correlation coefficients (r(2))>0.9945. The limits of detection (LODs) ranged from 45.1 to 236 ng L(-1). TCS in domestic waters was detected with the concentration of 2.08 microg L(-1). The spiked recoveries of three target compounds in river water, irrigating water, reclaimed water and domestic water samples were achieved in the range of 96.4-121%, 64.3-84.9%, 77.2-115% and 75.5-106%, respectively. As a result, this method can be successfully applied for the rapid and convenient determination of TCS, TCC and M-TCS in real water samples.
authors.affiliation: State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center of Eco-Environment Sciences, Chinese Academy of Sciences, Beijing, China.
authors.forename: Jie-Hong
authors.initials: JH
authors.lastname: Guo
authors.forename: Xing-Hong
authors.initials: XH
authors.lastname: Li
authors.forename: Xue-Li
authors.initials: XL
authors.lastname: Cao
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Xi-Zhi
authors.initials: XZ
authors.lastname: Wang
authors.forename: Xiao-Bai
authors.initials: XB
authors.lastname: Xu
mesh_terms: D002224:Carbanilides / Q000032:analysis*; D005591:Chemical Fractionation / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D003627:Data Interpretation, Statistical; D006863:Hydrogen-Ion Concentration; D009994:Osmolar Concentration; D012680:Sensitivity and Specificity; D012997:Solvents / Q000737:chemistry; D014260:Triclosan / Q000031:analogs & derivatives / Q000032:analysis*; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D002224:Carbanilides; D012997:Solvents; D014874:Water Pollutants, Chemical; D014867:Water; D014260:Triclosan; C009540:triclocarban