title: Identification of the novel HLA-G*010112 allele by sequencing genomic DNA of Korean individuals.
abstract: Human leukocyte antigen (HLA)-G is an immune modulator that inhibits the functions of cytotoxic T lymphocytes and natural killer cells. Immune modulation of HLA-G plays an important role in the prevention of fetal rejection. We found a novel substitution at nucleotide position 195 (G-T), codon 41 (Ala), in exon 2 of HLA-G. This substitution does not change the amino acid (GCG-->GCT).
authors.affiliation: School of Biological Science and Technology, Pochon CHA University, Sungnam, Korea.
authors.forename: J-G
authors.initials: JG
authors.lastname: Kim
authors.forename: H-S
authors.initials: HS
authors.lastname: Yun
authors.forename: J-K
authors.initials: JK
authors.lastname: Lee
authors.forename: K
authors.initials: K
authors.lastname: Kwack
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D005091:Exons; D015894:Genome, Human / Q000235:genetics*; D006680:HLA Antigens / Q000235:genetics*; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
chemical_list: D006680:HLA Antigens; D059951:HLA-G Antigens; C540900:HLA-G*01:01:12 antigen; D015395:Histocompatibility Antigens Class I; D004247:DNA