Tuberculosis in pregnancy in the UK.
Tuberculosis (TB) is a globally important cause of morbidity and mortality with an increasing incidence in women of reproductive ages. This descriptive study using the UK Obstetric Surveillance System demonstrates key differences in the presentation of TB during pregnancy compared with the nonpregnant population. The disease is limited to ethnic minority women, most commonly recent immigrants. Presentation may be atypical, with extrapulmonary disease as common as pulmonary. Clinicians should be aware of the potential for nonspecific presentation of the disease in pregnancy and consider the diagnosis in women, especially recently arrived immigrants, presenting with nonspecific symptoms.
Knight
M
M
National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK. marian.knight@npeu.ox.ac.uk
Kurinczuk
J J
JJ
Nelson-Piercy
C
C
Spark
P
P
Brocklehurst
P
P
D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D011256:Pregnancy Outcome / Q000453:epidemiology; D014376:Tuberculosis / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult