title: Photoacoustic tomography with a single detector in a reverberant cavity.
abstract: In conventional biomedical photoacoustic tomography (PAT), ultrasonic pulses generated through the absorption of nanosecond pulses of near-infrared light are recorded over an array of detectors and used to recover an image of the initial acoustic pressure distribution within soft tissue. This image is related to the tissue optical coefficients and therefore carries information about the tissue physiology. For high resolution imaging, a large-area detector array with a high density of small, sensitive elements is required. Such arrays can be expensive, so reverberant-field PAT has been suggested as a means of obtaining PAT images using arrays with a smaller number of detectors. By recording the reflections from an acoustically reverberant cavity surrounding the sample, in addition to the primary acoustic pulse, sufficient information may be captured to allow an image to be reconstructed without the need for a large-area array. An initial study using two-dimensional simulations was performed to assess the feasibility of using a single detector for PAT. It is shown that reverberant-field data recorded at a single detector are sufficient to reconstruct the initial pressure distribution accurately, so long as the shape of the reverberant cavity makes it ray-chaotic. The practicalities of such an approach to photoacoustic imaging are discussed.
authors.affiliation: Department of Medical Physics and Bioengineering, University College London, Gower Street, London, United Kingdom. bencox@mpb.ucl.ac.uk
authors.forename: B T
authors.initials: BT
authors.lastname: Cox
authors.forename: P C
authors.initials: PC
authors.lastname: Beard
mesh_terms: D000162:Acoustics; D017097:Electric Impedance; D005240:Feasibility Studies; D006801:Humans; D008027:Light; D008962:Models, Theoretical; D013995:Time; D014463:Ultrasonography