Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin.
Widespread use of mobile phones has increased the human exposure to electromagnetic fields (EMFs). It is required to investigate the effect of EMFs on the biological systems. In this paper the effect of mobile phone RF (910MHz and 940 MHz) on structure and function of HbA was investigated. Oxygen affinity was measured by sodium dithionite with UV-vis spectrophotometer. Structural changes were studied by circular dichroism and fluorescence spectroscopy. The results indicated that mobile phone EMFs altered oxygen affinity and tertiary structure of HbA. Furthermore, the decrease of oxygen affinity of HbA corresponded to the EMFs intensity and time of exposure.
Mousavy
Seyed Jafar
SJ
Institute of Biochemistry and Biophysics, University of Tehran, Iran.
Riazi
Gholam Hossein
GH
Kamarei
Mahmood
M
Aliakbarian
Hadi
H
Sattarahmady
Naghmeh
N
Sharifizadeh
Ahmad
A
Safarian
Shahrokh
S
Ahmad
Faizan
F
Moosavi-Movahedi
Ali Akbar
AA
D000817:Anilino Naphthalenesulfonates / Q000737:chemistry; D002021:Buffers; D040421:Cell Phone; D002942:Circular Dichroism; D005453:Fluorescence; D006454:Hemoglobins / Q000737:chemistry* / Q000378:metabolism* / Q000528:radiation effects; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000378:metabolism; D011489:Protein Denaturation; D017510:Protein Folding; D020836:Protein Structure, Quaternary; D011846:Radio Waves; D013696:Temperature; D013997:Time Factors
D000817:Anilino Naphthalenesulfonates; D002021:Buffers; D006454:Hemoglobins; C027132:1-anilino-8-naphthalenesulfonate; D010100:Oxygen