Cartilage repair using autologous chondrocyte implantation techniques.
Articular cartilage in adults has a poor ability to self-repair after injury. A variety of cartilage resurfacing techniques have the potential to improve the repair of cartilage defects and reduce the patient's disability. The most advanced of these techniques is autologous chondrocyte implantation. It promises to provide normal organogenesis leading to histologically and functionally normal articular cartilage. The procedure is technically demanding and requires patients to adhere to a specific post-operative rehabilitation protocol. Clinical results have so far been encouraging and have allowed many patients to resume high levels of sporting activity.
Schindler
Oliver S
OS
Droitwich Knee Clinic, St Andrews Road, Droitwich, Worcestershire, WR9 8YX. schindler@doctors.net.uk
D001182:Arthroscopy / Q000379:methods* / Q000639:trends; D002358:Cartilage, Articular / Q000166:cytology / Q000293:injuries* / Q000502:physiology / Q000601:surgery*; D018929:Cell Culture Techniques / Q000379:methods; D019902:Chondrocytes / Q000637:transplantation*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010353:Patient Education as Topic; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods; D012046:Rehabilitation / Q000379:methods; D020858:Tissue and Organ Harvesting / Q000379:methods; D014182:Transplantation, Autologous / Q000379:methods* / Q000639:trends; D016896:Treatment Outcome