title: The (mis) use of bone resorption markers in the context of bisphosphonate exposure, dental surgery and osteonecrosis of the jaw.
abstract: OBJECTIVE
  To evaluate the argument for use of bone resorption markers in patients exposed to bisphosphonates and requiring dental surgery to prevent development of osteonecrosis of the jaw.
  
  
  METHODS
  Review of literature.
  
  
  RESULTS
  5 primary reports and a number of reviews were considered.
  
  
  CONCLUSIONS
  There is insufficient evidence to recommend use of bone resorption markers in patients exposed to bisphosphonates prior to dental surgery as a routine test to assess risk of osteonecrosis of the jaw.
authors.affiliation: Department of Pathology and Molecular Medicine, McMaster University and Hamilton Regional Laboratory Medicine Program, Canada. donwauc@mcmaster.ca
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Don-Wauchope
authors.forename: David E C
authors.initials: DE
authors.lastname: Cole
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D001862:Bone Resorption / Q000378:metabolism*; D004164:Diphosphonates / Q000627:therapeutic use*; D006801:Humans; D007571:Jaw Diseases / Q000473:pathology*; D019647:Oral Surgical Procedures; D010020:Osteonecrosis / Q000473:pathology*
chemical_list: D015415:Biomarkers; D004164:Diphosphonates