title: Serious psychological distress among persons with epilepsy based on the 2005 California Health Interview Survey.
abstract: OBJECTIVE
  To compare the prevalence of self-reported serious psychological distress using the Kessler 6 (K6) in persons with a history of epilepsy (PWE) to those without epilepsy from a population-based survey.
  
  
  METHODS
  Data were analyzed from adults aged >or=18 years (n = 43,020) who participated in the 2005 California Health Interview Survey (CHIS).
  
  
  RESULTS
  California adults with a history of epilepsy, after controlling for demographics and comorbidities, reported higher rates of feeling nervous [odds ratio (OR) 2.22], feeling hopeless (OR 1.35), feeling restless (OR 2.07), feeling depressed (OR 3.14), and feeling worthless (OR 2.57), and reported that everything has been an effort (OR 2.28) in the last 30 days. The K6 score showed that serious psychological distress is more common in PWE (OR 2.24). After adjusting for demographics, comorbidities, and serious psychological distress, PWE are more likely to report having 14 or more physical, mental, and general unhealthy days in the last 30 days.
  
  
  CONCLUSIONS
  PWE have significantly higher rates of serious psychological distress and poor health-related quality of life after controlling for demographics, comorbidities. These comorbid conditions need to be factored into any comprehensive treatment strategy for managing PWE to achieve optimum quality of life.
authors.affiliation: Department of Neurology, Ohio State University, Columbus, Ohio 43210, USA. j.layne.moore@osumc.edu
authors.forename: J
authors.initials: J
authors.lastname: Layne Moore
authors.forename: John O
authors.initials: JO
authors.lastname: Elliott
authors.forename: Bo
authors.initials: B
authors.lastname: Lu
authors.forename: Emily T
authors.initials: ET
authors.lastname: Klatte
authors.forename: Christine
authors.initials: C
authors.lastname: Charyton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002140:California / Q000453:epidemiology; D004827:Epilepsy / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D012189:Retrospective Studies; D013315:Stress, Psychological / Q000453:epidemiology* / Q000523:psychology; D055815:Young Adult