Real correlation time measurement in laser speckle contrast analysis using wide exposure time range images.
In laser speckle contrast analysis (LASCA) used for imaging of blood flow, besides the moving blood cells, the speckle pattern is also influenced by the imaging system and scattering properties of the laser-illuminated static surface. A latex microsphere (650 nm size) emulsion was covered with scattering semitransparent materials (Teflon foils, tracing paper). Speckle images were recorded with different exposure times (0.2 ms-500 ms), and correlation times were determined by parameterizing the theoretical contrast-exposure time function. The correlation times obtained for covered and uncovered microsphere emulsions were in good agreement. The possibility of obtaining comparable, setup-independent results in blood perfusion monitoring can contribute to better applicability of LASCA.
Smausz
Tomi
T
Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, H-6720 Szeged, Hungary. tomi@physx.u-szeged.hu
Zölei
Dániel
D
Hopp
Béla
B
D000818:Animals; D001783:Blood Flow Velocity; D004655:Emulsions; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007834:Lasers; D007840:Latex; D008863:Microspheres; D008954:Models, Biological; D010209:Paper; D011138:Polytetrafluoroethylene; D012542:Scattering, Radiation; D013997:Time Factors
D004655:Emulsions; D007840:Latex; D011138:Polytetrafluoroethylene