[Determination of melamine residue in foods using gas chromatography-tandem mass spectrometry].
A method of gas chromatography-tandem mass spectrometry (GC-MS/MS) was developed for melamine residue in foods. The sample was extracted under ultrasonication with trichloroacelic acid (TCA), the protein in the sample was precipitated with zinc acetate solution. The extract was centrifuged, filtered, purified, derivatized and detected using GC-MS/MS in multiple-reaction monitoring mode. The limit of detection for melamine was 1 microg/kg. The good linearity in the range of 0.1 - 100 microg/L was obtained. The relative standard deviation (RSD) of peak area was less than 9%. This method has been applied to the analysis of melamine in milk powder, toffee, milk beverages, biscuits and other foods. It provides a method for the detection of abuse of melamine.
Lu
Yeju
Y
National Center for Quality Supervision and Test of Agricultural-Avocation Processed Food, Hefei 230051, China. luyeju998@sina.com
Shu
Yong
Y
Zhao
Chengshi
C
D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D016014:Linear Models; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014227:Triazines / Q000032:analysis* / Q000302:isolation & purification
D014227:Triazines; C011907:melamine