Clinical and molecular epidemiology of human parainfluenza virus 4 infections in hong kong: subtype 4B as common as subtype 4A.
In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.
Lau
Susanna K P
SK
Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong.
Li
Kenneth S M
KS
Chau
Kam-yu
KY
So
Lok-yee
LY
Lee
Rodney A
RA
Lau
Yu-lung
YL
Chan
Kwok-hung
KH
Lim
Wilina W L
WW
Woo
Patrick C Y
PC
Yuen
Kwok-yung
KY
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D005838:Genotype; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009305:Nasopharynx / Q000821:virology; D029482:Parainfluenza Virus 4, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019351:Rubulavirus Infections / Q000453:epidemiology* / Q000821:virology; D017422:Sequence Analysis, DNA; D055815:Young Adult
D012367:RNA, Viral