title: Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest.
abstract: BACKGROUND
  The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated.
  
  
  RESULTS
  Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient.
  
  
  CONCLUSIONS
  OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary.
authors.affiliation: Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Takagi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yasuda
authors.forename: Jun
authors.initials: J
authors.lastname: Takahashi
authors.forename: Morihiko
authors.initials: M
authors.lastname: Takeda
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nakayama
authors.forename: Kenta
authors.initials: K
authors.lastname: Ito
authors.forename: Masanori
authors.initials: M
authors.lastname: Hirose
authors.forename: Yuji
authors.initials: Y
authors.lastname: Wakayama
authors.forename: Koji
authors.initials: K
authors.lastname: Fukuda
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shimokawa
mesh_terms: D000328:Adult; D003329:Coronary Vasospasm; D017147:Defibrillators, Implantable; D005260:Female; D006323:Heart Arrest / Q000401:mortality* / Q000503:physiopathology*; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D014693:Ventricular Fibrillation