Gynaecological uses of a new class of steroids: the selective progesterone receptor modulators.
Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo. This review evaluates the actual and potential usefulness of SPRMs in gynaecology.
Pintiaux
Axelle
A
Chabbert-Buffet
Nathalie
N
Foidart
Jean-Michel
JM
D000028:Abortion, Induced; D003267:Contraception; D005260:Female; D006801:Humans; D011247:Pregnancy; D011980:Receptors, Progesterone / Q000819:agonists* / Q000037:antagonists & inhibitors*; D013256:Steroids / Q000627:therapeutic use*; D014591:Uterine Diseases / Q000188:drug therapy*
D011980:Receptors, Progesterone; D013256:Steroids