"Mycobacterium tilburgii," a newly described, uncultivated opportunistic pathogen.
Molecular methods are increasingly used to identify pathogens that are difficult to cultivate. We report a case of disseminated infection with "Mycobacterium tilburgii," a proposed species that has never been cultivated. The case illustrates the diagnostic utility of sequence analysis of the 16S rRNA gene directly from clinical specimens.
Palmore
Tara N
TN
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. tpalmore@mail.nih.gov
Shea
Yvonne R
YR
Conville
Patricia S
PS
Witebsky
Frank G
FG
Anderson
Victoria L
VL
Rupp Hodge
Irene P
IP
Holland
Steven M
SM
D004269:DNA, Bacterial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D006801:Humans; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification* / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000382:microbiology*; D009894:Opportunistic Infections / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D011860:Radiography, Abdominal; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S