Clinical characteristics of metastatic tumors to the ovaries.
Approximately 5-30% of the ovarian cancers are metastatic malignancies. The prevalence of metastatic ovarian tumors varies with the incidence rates and spread patterns of primary malignancies. We evaluated the prevalence, pre- and postoperative characteristics of metastatic ovarian cancer in Korean women. We reviewed the records for 821 ovarian malignancies with pathological consultation from 1996-2006 and recorded patient demographical, radiological, histopathological, and survival data. The study included 112 cases of histologically confirmed metastatic ovarian cancer. Metastatic ovarian cancer accounted for 13.6% of all ovarian malignancy, primarily arising from the gastrointestinal tract. The preoperative detection rate with imaging was 75%, and none of the radiological or serological features were useful for differential diagnosis. In multivariate analysis for prognostic variables, the only significant factor was the primary tumor site (p=0.004). Furthermore, extensive resection increased survival for some patients. The differential diagnosis of metastatic ovarian cancer can be problematic, so multiple diagnostic approaches are necessary. The extent of cytoreductive surgery for this type of tumor must be decided on a case-by-case basis.
Lee
Sung-Jong
SJ
Department of Obstetrics and Gynecology, The Catholic University of Korea, Seoul, Korea.
Bae
Jeong-Hoon
JH
Lee
A-Won
AW
Tong
Seo-Yun
SY
Park
Yong-Gyu
YG
Park
Jong-Sup
JS
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D000328:Adult; D018394:CA-125 Antigen / Q000097:blood; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008499:Medical Records; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D010052:Ovariectomy; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis
D018394:CA-125 Antigen