Evaluation de l'activité antifongique de deux dérivés et test d'innocuitéin vivo de shampooings à visée antipelliculaire ainsi formulés.
Synopsis Two thirds of the population suffer more or less severely from dandruff, a dermatological disease associated with the yeast Pityrosporum ovale. This paper demonstrates the anti-fungal activity of two substances commonly used in hair cosmetics: zinc pyrithione and piroctone olamine, at several concentrations. Based on an optimum concentration, two shampoos were formulated in order to determine the cutaneous tolerance of the finished cosmetics. A profilometry study was carried out using negative impressions obtained from skin prints to calculate the cutaneous tolerance. This study revealed the superiority of the piroctone olamine as an anti-fungal substance and its cutaneous tolerance was also better.
Rivalland
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P
Laboratoire de Pharmacie Industrielle et Cosmétologie, Centre Atlantique d'Etude en Cosmétologie, 68 Bd Eugéne Orieux - 44000 Nantes, France.
Coiffard
L
L
Lelaure
M
M
Roeck-Holtzhauer
Y D
YD