Report of two cases of Rosai-Dorfman disease with only skin involvement.
Although cutaneous localization associated with lymphadenopathy is a common phenomenon in Rosai-Dorfman disease, cutaneous and subcutaneous involvement alone occurs only rarely. We herein report two cases of cutaneous lesions in the absence of lymph node localization and systemic symptoms or signs. Characteristic features of the disease, such as emperipolesis, were evident in both cases.
Mourmouras
V
V
Department of Human Pathology and Oncology, Section of Anatomic Pathology, University of Siena, Italy.
Falzarano
S M
SM
Miracco
C
C
D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D015415:Biomarkers; D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009418:S100 Proteins / Q000032:analysis; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D015415:Biomarkers; D009418:S100 Proteins; C067980:CD68 antigen, human; D000097382:CD68 Molecule