title: Evaluation of early and midterm results of offpump coronary artery bypass in patients with left main disease.
abstract: OBJECTIVE
  This study evaluated the early and midterm results of offpump coronary artery bypass (OPCAB) for left main coronary artery (LMCA) stenosis.
  
  
  METHODS
  Patients treated between November 2001 and December 2006, during which isolated coronary artery bypass grafting (CABG) was performed without cardiopulmonary bypass in principle, were included. Isolated CABG was performed in 206 patients, of whom 62 (30.1%) had LMCA stenosis >50%.
  
  
  RESULTS
  The in-hospital mortality rate (LMCA stenosis > 50%, 1.6%; LMCA stenosis <or=50%, 0.7%, p = 0.512), the incidence of postoperative complications, and the midterm survival rate (LMCA stenosis succeeds50%, 86.7 +/- 5.2%/5 years, LMCA stenosis<or=50%, 89.6 +/- 3.8%/5 years, p = 0.21) did not significantly differ between the two groups. Conversion was significantly frequent in patients with LMCA stenosis >75% and severe stenosis >90% in the right coronary artery (RCA) trunk.
  
  
  CONCLUSIONS
  Patients with LMCA stenosis can undergo OPCAB safely and the midterm results are good. As conversion was significantly frequent in patients with severe LMCA and RCA trunk stenosis, adequate preparation for pump application is necessary.
authors.affiliation: Department of Cardiovascular Surgery, Chiba University Hospital, Chiba, Japan. Mizuho.Imamaki1107@gmail.com
authors.forename: Mizuho
authors.initials: M
authors.lastname: Imamaki
authors.forename: Kaoru
authors.initials: K
authors.lastname: Matsuura
authors.forename: Manabu
authors.initials: M
authors.lastname: Sakurai
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Shimura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ishida
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000368:Aged; D047549:Coronary Artery Bypass, Off-Pump / Q000401:mortality / Q000706:statistics & numerical data*; D023921:Coronary Stenosis / Q000601:surgery*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors