title: A case study of delayed HIV-1 seroconversion highlights the need for Combo assays.
abstract: This report describes a case in which a patient took at least four months to seroconvert to anti-HIV positivity. A concomitant CMV infection probably contributed to the profound immune suppression observed. It is essential that fourth generation HIV antigen/antibody combo assays be used to ensure that such cases are not missed.
authors.affiliation: Department of Microbiology, Shrewsbury and Telford Hospital NHS Trust, Telford TF1 6TF, UK. sue.skidmore@sath.nhs.uk
authors.forename: S
authors.initials: S
authors.lastname: Skidmore
authors.forename: S
authors.initials: S
authors.lastname: Devendra
authors.forename: J
authors.initials: J
authors.lastname: Weaver
authors.forename: J
authors.initials: J
authors.lastname: Short
authors.forename: H
authors.initials: H
authors.lastname: Osman
authors.forename: E
authors.initials: E
authors.lastname: Smit
mesh_terms: D015492:AIDS Serodiagnosis; D017088:AIDS-Related Opportunistic Infections; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D045363:Pneumocystis carinii / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000150:complications; D013997:Time Factors; D055815:Young Adult