Measurement of geometric deformation of lumbar intervertebral discs under in-vivo weightbearing condition.
Quantitative data of spinal intervertebral disc deformation is instrumental for investigation of spinal disc pathology. In this study, we employed a combined dual fluoroscopic imaging system and the MR imaging technique to determine the lumbar disc deformation in living human subjects. Discs at L2-3, L3-4 and L4-5 levels were investigated in 8 normal subjects. The geometric deformation of the discs under full body weight loading condition (upright standing) was determined using the supine, non-weightbearing condition as a reference. The average maximum tensile deformation was -21% in compression and 24% in tension, and maximum shear deformation on the disc surface reached 26%. The data indicated that different portions of the disc are under different tensile and shear deformation. Further, discs of L2-3, L3-4 and L4-5 have different deformation behavior under the physiological weightbearing condition. In general, the higher level discs have higher deformation values. The technique used in this study can be used to investigate the deformation behaviors of diseased discs as well as the efficacy of different surgical modalities at restoring normal disc deformation patterns.
Wang
Shaobai
S
Bioengineering Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, GRJ 1215 Boston, MA 02114, USA.
Xia
Qun
Q
Passias
Peter
P
Wood
Kirkham
K
Li
Guoan
G
D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007403:Intervertebral Disc / Q000033:anatomy & histology* / Q000502:physiology*; D008159:Lumbar Vertebrae / Q000033:anatomy & histology* / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D013718:Tensile Strength; D016474:Weight-Bearing