title: [Update on the treatment of genital herpes].
abstract: Genital herpes is a chronic infection characterized by periodic reactivation. It can produce symptomatic disease in the host although asymptomatic viral excretion can also occur. It is currently the main cause of genital ulceration and an important public health problem that has substantial clinical, psychological, and economic repercussions. This review analyzes the currently available therapeutic options and regimens, which are based mainly on systemic use of antiviral agents such as aciclovir, valacyclovir, and famciclovir. In addition, special emphasis is placed on the prevention and management of this infection in specific situations, such as pregnant, pediatric, and immunocompromised patients.
authors.affiliation: Servicio de Dermatología, Hospital Clínico Universitario, Valencia, España. jmmart@eresmas.com
authors.forename: J M
authors.initials: JM
authors.lastname: Martín
authors.forename: G
authors.initials: G
authors.lastname: Villalón
authors.forename: E
authors.initials: E
authors.lastname: Jordá
mesh_terms: D000293:Adolescent; D000818:Animals; D000998:Antiviral Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002648:Child; D002649:Child Abuse; D002675:Child, Preschool; D004353:Drug Evaluation, Preclinical; D005260:Female; D006558:Herpes Genitalis / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control / Q000635:transmission / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D018258:Herpesvirus 2, Human / Q000302:isolation & purification; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008297:Male; D051379:Mice; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D012008:Recurrence; D012883:Skin Ulcer / Q000209:etiology
chemical_list: D000998:Antiviral Agents