New domino reaction for the selective synthesis of tetracyclic cinnolino[5,4,3-cde]cinnolines.
A new domino reaction for the highly selective synthesis of tetracyclic cinnolino[5,4,3-cde]cinnolines using steric control was described. In this reaction, the use of anthenes with aliphatic groups (R(1)) leads to cinnolino[5,4,3-cde]cinnolines whereas anthenes with aryl groups (R(1)) result in N-amino-1,8-dioxoacridines.
Jiang
Bo
B
School of Chemistry and Chemical Engineering, Xuzhou Normal University, Jiangsu, PR China.
Hao
Wen-Juan
WJ
Zhang
Jin-Peng
JP
Tu
Shu-Jiang
SJ
Shi
Feng
F
D018360:Crystallography, X-Ray; D003500:Cyclization; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
D006574:Heterocyclic Compounds, 2-Ring; D006576:Heterocyclic Compounds, 4 or More Rings; C540238:cinnolino(5,4,3-cde)cinnoline; C476282:cinnoline