Dapsone, danazol, and intrapartum splenectomy in refractory ITP complicating pregnancy.
Currently there is no consensus on the treatment of refractory idiopathic thrombocytopenic purpura (ITP) complicating pregnancy. Our patient with chronic ITP complicating pregnancy, who was refractory to steroids, dapsone, and danazol, was treated successfully with intrapartum splenectomy.
Varghese
Lilly
L
Obstetrics and Gynecology Unit 1, Christian Medical College, Ida Scudder Road, Vellore, India. lillyanil@cmcvellore.ac.in
Viswabandya
Auro
A
Mathew
Arpit Jacob
AJ
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002585:Cesarean Section; D003613:Danazol / Q000627:therapeutic use*; D003622:Dapsone / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use; D004965:Estrogen Antagonists / Q000627:therapeutic use*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D013156:Splenectomy
D000893:Anti-Inflammatory Agents; D004965:Estrogen Antagonists; D005938:Glucocorticoids; D003907:Dexamethasone; D003622:Dapsone; D003613:Danazol; D011241:Prednisone