Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollis.
BACKGROUND
Anterocollis is a form of cervical dystonia characterized by forward neck flexion. While botulinum toxin is the treatment of choice for cervical dystonia, patients with anterocollis, who receive injections into the sternocleidomastoid and anterior scalene muscles, represent a disproportionate number of treatment failures. Deep cervical muscles such as the longus colli likely play an important role in neck flexion but are not routinely injected.


OBJECTIVE
To describe a technique for longus colli injection in cases of anterocollis and to report the clinical outcomes of 10 such injections of botulinum toxin.


METHODS
Three patients were referred for evaluation and treatment of anterocollis. All had previous treatment failures with sternocleidomastoid/anterior scalene injections or no activity noted on needle EMG investigation of these muscles. All patients received injections of botulinum toxin into the longus colli under fluoroscopic and EMG guidance.


RESULTS
All patients experienced symptomatic improvement (eight of 10 injections). Two patients reported mild dysphagia without serious complications after dose increases in botulinum toxin.


CONCLUSIONS
Incomplete muscle selection may be one cause of treatment failures in anterocollis. Deep cervical flexors such as the longus colli represent an under-recognized potential target for symptomatic treatment of anterocollis.
Glass
Graham A
GA
Department of Neurology, UCSF Medical Center, San Francisco, CA 94143, USA. graham.glass@ucsf.edu
Ku
Stephen
S
Ostrem
Jill L
JL
Heath
Susan
S
Larson
Paul S
PS
D000328:Adult; D001905:Botulinum Toxins / Q000008:administration & dosage*; D004576:Electromyography / Q000379:methods*; D005471:Fluoroscopy / Q000379:methods; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D009334:Neck Muscles / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000502:physiology; D014103:Torticollis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
D001905:Botulinum Toxins