Determination of some congeners of polychlorinated dibenzo-p-dioxins (PCDDs) in milk using gas chromatography.
A method for determination of four congeners of polychlorinated dibenzo-p-dioxins (PCDDs) namely, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin (PeCDD), 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin (HxCDD) and 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in milk is presented. Limit of detection (LOD) was found to be 0.002 ng for PeCDD while for other three it was found to be 0.005 ng. Recoveries for PeCDD were checked by spiking the milk at 0.020, 0.050 and 0.10 ng g(-1) levels and recovered in the range of 81.03%-120.17%. TCDD, HxCDD and HpCDD were checked at 0.05, 0.10 and 0.5 ng g(-1) spiked levels and recovered in the range of 80.47%-133.30%, 88.40%-128.02% and 76.97%-132.55% respectively. Limit of quantification (LOQ) was found to be 0.1 ng g(-1) for PeCDD whereas 0.5 ng g(-1) for others. %RSD was in the range of 4.30-15.79.
Khan
Iffat Abdul Tawab
IA
Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan. iffku@yahoo.com
Maqsood
Zahida Tasneem
ZT
D000818:Animals; D002849:Chromatography, Gas / Q000379:methods*; D008892:Milk / Q000737:chemistry*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis
D000072317:Polychlorinated Dibenzodioxins; C051452:1,2,3,7,8-pentachlorodibenzo-p-dioxin; C046838:1,2,3,6,7,8-hexachlorodibenzodioxin; C046839:1,2,3,4,6,7,8-heptachlorodibenzodioxin