Pupillometric characteristics in patients with choroidal neovascularization due to age-related macular degeneration.
OBJECTIVE
To study the pupillary light reflex in patients with choroidal neovascularization due to age-related macular degeneration (AMD).


METHODS
The study included 15 patients with AMD and 15 control subjects. A full recording of the pupil's reaction to light was registered and the following eight parameters were measured and reported: baseline pupil (R1), latency (T1), minimum pupil radius (R2), amplitude (AMP), maximum constriction velocity (VCmax), maximum constriction acceleration (ACmax), time for maximum velocity (T2), and time for maximum constriction (T3).


RESULTS
All variables measured presented alterations in the AMD group and a number of them were significantly reduced in the AMD group.


CONCLUSIONS
The presence of neovascular AMD significantly affects the pupil's response to light stimulus when compared to normal subjects.
Brozou
Catherine
C
Laboratory of Clinical Neurophysiology, Aristotle University of Thessaloniki, Thessaloniki - Greece. brozou@yahoo.com
Fotiou
Dimitrios
D
Androudi
Sofia
S
Theodoridou
Evelyn
E
Giantselidis
Charalambos
C
Alexandridis
Alexandros
A
Brazitikos
Periklis
P
D020256:Choroidal Neovascularization / Q000209:etiology / Q000503:physiopathology*; D003623:Dark Adaptation; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008027:Light; D008268:Macular Degeneration / Q000150:complications / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology* / Q000528:radiation effects; D011681:Pupil Disorders / Q000503:physiopathology*; D012025:Reflex, Pupillary / Q000502:physiology*