Rat models for bariatric surgery and surgery for type 2 diabetes mellitus.
Type 2 diabetes mellitus being one of the most prevalent diseases in the world has led to a variety of research using animal models. This review focuses on various rat models to study the effect that surgical procedures have on type 2 diabetes mellitus and obesity. Rat models can be classified as Obese Diabetic, Non-Obese Diabetic, Obese Non-Diabetic, and Non-Obese Non-Diabetic. Here, we have discussed the particular characteristics of each rat so that it can provide the appropriate model to study different pathological processes involve in type 2 Diabetes and obesity.
Mistry
Sheetal Bharat
SB
606/B Kalpataru Classic, Chincholi Bunder Road. Malad West, Mumbai, 400064, Maharashtra, India.
Omana
Juan J
JJ
Kini
Subhash
S
D000818:Animals; D050110:Bariatric Surgery; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000601:surgery*; D023421:Models, Animal; D009765:Obesity / Q000150:complications / Q000601:surgery*; D051381:Rats