title: Occult large epiphyseal solitary plasmacytoma at multidetector row computer tomography detected by magnetic resonance imaging.
abstract: Myeloma or Kahler-Bozzolo disease represents around 1% of all malignant tumors and 10% of the haematological variety; it is a B-lymphocellular malignant neoplasia which originates from plasma cells that produce monoclonal immunoglobulin, infiltrating in and destroying the adjacent bone tissue. Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma. It is known that initial osteolysis may not be shown through radiographic examination or CT; the lysis only becomes evident when there is a bone loss of over 50%, usually in the presence of a > or = 0.5 cm focal lesion. We present here the clinical-radiological aspects of a solitary bone plasmacitoma (SBP) of the knee of a 35 year old male which was not evidenced at radiological examination or CT but was evident as a 3 cm focal alteration at MR. The lesion was confirmed by PET and the histological diagnosis was performed by a CT guided bioptic sample.
authors.affiliation: Department of Clinical Sciences, Unit of Radiological Sciences, University of Parma, Parma Hospital, Parma, Italy. massimo.defilippo@unipr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: De Filippo
authors.forename: Franceso
authors.initials: F
authors.lastname: Pogliacomi
authors.forename: Ugo
authors.initials: U
authors.lastname: Albisinni
authors.forename: Salvatore
authors.initials: S
authors.lastname: Quinto
authors.forename: Carlo
authors.initials: C
authors.lastname: Bocchi
authors.forename: Nicola
authors.initials: N
authors.lastname: Sverzellati
authors.forename: Stefano
authors.initials: S
authors.lastname: Lipia
authors.forename: Maurizio
authors.initials: M
authors.lastname: Zompatori
mesh_terms: D000328:Adult; D001706:Biopsy; D015519:Bone Density; D004838:Epiphyses / Q000000981:diagnostic imaging; D005266:Femoral Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005269:Femur / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D049268:Positron-Emission Tomography; D013997:Time Factors; D036542:Tomography, Spiral Computed