title: Can radiotherapy affect the apical sealing ability of resin-based root canal sealers?
abstract: BACKGROUND
  The authors conducted a study to assess the influence of radiotherapy on the apical sealing ability of one recently introduced resin-based root canal sealer and two sealers that have been in use for several years.
  
  
  METHODS
  The authors divided 90 human maxillary anterior teeth into three groups according to the type of root canal sealer used and, using lateral condensation, obturated the roots with gutta-percha. They randomly divided all roots into two main groups according to the presence or absence of radiotherapy. For the groups that received irradiation, a dose of 60 gray was delivered in fractions of 1.8 Gy per day, five days a week for seven weeks. The authors then performed the centrifuging dye penetration test to determine apical leakage for each specimen.
  
  
  RESULTS
  The authors compared the specimens in the groups that received radiotherapy after endodontic treatment with the specimens in the groups that did not undergo radiotherapy after endodontic treatment. They found that mean apical leakage was slightly higher in the radiotherapy groups, but they did not observe any statistical difference between the groups (P > .05). In the groups that did not undergo radiotherapy, the mean apical leakage for the specimens in the MM-Seal (MicroMega, Besançon, France [not marketed in the United States]), AH Plus (Dentsply DeTrey GmbH, Konstanz, Germany) and AH 26 (Dentsply DeTrey GmbH) groups was 2.52 +/- 0.42 millimeters, 2.85 +/- 0.52 mm and 3.73 +/- 0.41 mm, respectively. In the groups that underwent radiotherapy, the mean apical leakage for the specimens in the MM-Seal, AH Plus and AH 26 groups was 2.72 +/- 0.55 mm, 2.96 +/- 0.47 mm and 3.93 +/- 0.61 mm, respectively.
  
  
  CONCLUSIONS
  The apical sealing ability of the resin-based root canal sealers decreased slightly when radiotherapy was administered, although there was no statistically significant difference.
  
  
  CONCLUSIONS
  Clinicians can safely use a resin-based root canal sealer in patients receiving radiotherapy.
authors.affiliation: Department of Operative Dentistry and Endodontics, Ondokuz Mayis University, Faculty of Dentistry, 55139 Kurupelit-Samsun, Turkey. bodrumlu@omu.edu.tr
authors.forename: Emre
authors.initials: E
authors.lastname: Bodrumlu
authors.forename: Aysun
authors.initials: A
authors.lastname: Avsar
authors.forename: Ahmet Deniz
authors.initials: AD
authors.lastname: Meydan
authors.forename: Nuray
authors.initials: N
authors.lastname: Tuloglu
mesh_terms: D001840:Dental Bonding; D003763:Dental Leakage / Q000209:etiology / Q000517:prevention & control*; D003799:Dental Stress Analysis; D006801:Humans; D007180:Incisor; D008422:Materials Testing; D008437:Maxilla; D011878:Radiotherapy / Q000009:adverse effects*; D019279:Resin Cements / Q000528:radiation effects*; D012387:Root Canal Filling Materials / Q000528:radiation effects*; D012389:Root Canal Obturation
chemical_list: D019279:Resin Cements; D012387:Root Canal Filling Materials