Prediction of perinatal outcomes in patient with pre-eclampsia: maternal hyperoxygenation test on fetal Doppler flow.
OBJECTIVE
Investigate if the maternal hyperoxygenation test in pregnancy with pre-eclampsia could be used for prediction of perinatal outcomes.


METHODS
Fifty-four singleton pre-eclampsia pregnant women were enrolled in the present study. Positive hyperoxygenation test was defined as an increase of the middle cerebral artery (MCA) or the ductus venosus (DV) pulsatility index (PI), or a decrease of the uterine artery or the umbilical artery (UA) PI by at least 20%. Results of hyperoxygenation test were analyzed for the correlation with perinatal outcomes.


RESULTS
Fetuses with positive hyperoxygenation test of the MCA had a birth weight less than the negative group significantly. Furthermore, there was a significantly higher rate ofsmall for gestational age (SGA) neonates and admission to the neonatal intensive care unit (NICU) in cases with positive test of the MCA.


CONCLUSIONS
The present study shows the correlation of positive hyperoxygenation test of the MCA and low birth weight, SGA, and NICU admission.
Chanthasenanont
Athita
A
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Thammasat University, Pathumthani, Thailand. athitaka@gmail.com
Somprasit
Charintip
C
Pongrojpaw
Densak
D
D001724:Birth Weight; D005260:Female; D005323:Fetal Monitoring; D005333:Fetus / Q000098:blood supply*; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood*; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D011673:Pulsatile Flow; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging; D014599:Uterus / Q000098:blood supply
D010100:Oxygen