title: Clinical-epidemiological characteristics of atopic dermatitis in children of junior school level in Tbilisi.
abstract: Atopic dermatitis (AD) is one of the most actual problems in modern pediatrics. Sharpness of problem in children's population is not only due to wide prevalence of Atopic dermatitis, but its debut in early age and chronization tendency, which is followed by breach of social adaptation, decrease of life degree and children's invalidization. Seeking for revelation of atopic dermatitis risk factors, observative, analytical retrospective survey - case-control was conducted. With the mentioned aim in mind (in five districts of city Tbilisi, five schools were chosen by method of cluster randomization in which 2454 children were interviewed according to beforehand produced epidemiological questioner. Statistical treatment of resulted outcomes was prepared according to program package SPSS) the residents were divided into two groups: primary or sample group with 278 patients suffering from atopic dermatitis and control group - with 300 conditionally healthy children. Wide area epidemiological study estimated prevalence of Atopic Dermatitis figure (11.3%) in junior school level children of Tbilisi population and significant variation (5.4-28.3%) of figures of prevalence of atopic dermatitis according to administrative districts; manifestation of Atopic Dermatitis in junior school level children of Tbilisi population mostly (39.6%) in 6-7 years old children and reveal with the same frequency in representatives of both sex. Studying of Atopic Dermatitis revealed important risk factors of disease development: genetic load with allergic disease from mother side (OR- 10.27; 95% CI - 7.08-27.04); food allergy till one year (OR- 10.27; 95% CI -6.17-17.24); loaded perinatal anamnesis with medicinal allergy (OR- 9.09; 95% CI -1.98-57.94); loaded perinatal anamnesis with food allergy (OR- 7.99; 95% CI -3.17-21.38); early artificial feeding (OR-5.29; 95 CI 3.30-8.51); not conducting immunoprevention vaccine (OR- 4.98; 95% CI -0.99-33.65); cat in the family (OR- 3.95; 95% CI - 2.61-5.98); frequent conflicts in the family (OR-1.81; 95% CI - 1.22-2.69) most of which are controllable and their correction is the real perspective for decrease of disease.
authors.affiliation: Iv. Javakhishvili Tbilisi State University, Tbilisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Mgeladze
authors.forename: R
authors.initials: R
authors.lastname: Karseladze
authors.forename: L
authors.initials: L
authors.lastname: Zhorzholiani
authors.forename: E
authors.initials: E
authors.lastname: Karseladze
mesh_terms: D000293:Adolescent; D002648:Child; D003876:Dermatitis, Atopic / Q000453:epidemiology*; D005260:Female; D005846:Georgia (Republic) / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D011795:Surveys and Questionnaires