Obstructive sleep apnea among obese patients with type 2 diabetes.
OBJECTIVE
To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes.


METHODS
Unattended polysomnography was performed in 306 participants.


RESULTS
Over 86% of participants had OSA with an apnea-hypopnea index (AHI) >or=5 events/h. The mean AHI was 20.5 +/- 16.8 events/h. A total of 30.5% of the participants had moderate OSA (15 <or= AHI <30), and 22.6% had severe OSA (AHI >or=30). Waist circumference (odds ratio 1.1; 95% CI 1.0-1.1; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% CI 1.0-1.2; P = 0.03).


CONCLUSIONS
Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist circumference and BMI.
Foster
Gary D
GD
Temple University, Philadelphia, Pennsylvania, USA. gfoster@temple.edu
Sanders
Mark H
MH
Millman
Richard
R
Zammit
Gary
G
Borradaile
Kelley E
KE
Newman
Anne B
AB
Wadden
Thomas A
TA
Kelley
David
D
Wing
Rena R
RR
Sunyer
F Xavier Pi
FX
Darcey
Valerie
V
Kuna
Samuel T
ST
D000368:Aged; D001827:Body Height; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000453:epidemiology; D010101:Oxygen Consumption; D017286:Polysomnography; D012120:Respiration Disorders / Q000145:classification / Q000453:epidemiology / Q000503:physiopathology; D012307:Risk Factors; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology; D012895:Sleep, REM / Q000502:physiology; D055105:Waist Circumference
D006442:Glycated Hemoglobin