title: Clinical and molecular epidemiology of human parainfluenza virus 4 infections in hong kong: subtype 4B as common as subtype 4A.
abstract: In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.
authors.affiliation: Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong.
authors.forename: Susanna K P
authors.initials: SK
authors.lastname: Lau
authors.forename: Kenneth S M
authors.initials: KS
authors.lastname: Li
authors.forename: Kam-yu
authors.initials: KY
authors.lastname: Chau
authors.forename: Lok-yee
authors.initials: LY
authors.lastname: So
authors.forename: Rodney A
authors.initials: RA
authors.lastname: Lee
authors.forename: Yu-lung
authors.initials: YL
authors.lastname: Lau
authors.forename: Kwok-hung
authors.initials: KH
authors.lastname: Chan
authors.forename: Wilina W L
authors.initials: WW
authors.lastname: Lim
authors.forename: Patrick C Y
authors.initials: PC
authors.lastname: Woo
authors.forename: Kwok-yung
authors.initials: KY
authors.lastname: Yuen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D005838:Genotype; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009305:Nasopharynx / Q000821:virology; D029482:Parainfluenza Virus 4, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019351:Rubulavirus Infections / Q000453:epidemiology* / Q000821:virology; D017422:Sequence Analysis, DNA; D055815:Young Adult
chemical_list: D012367:RNA, Viral