title: Herpes zoster laryngitis with intractable hiccups.
abstract: A 73-year-old man presented to our hospital with a sore throat (left-sided) and hiccups. The patient had mucosal swelling and erosions affecting the left posterior pillar, base of tongue, epiglottis, arytenoid, and aryepiglottic fold. As the laryngeal mucosal edema became worse, herpetic vesicles and erosions developed on the left cavum conchae, external auditory canal, and palate. The patient was treated with acyclovir and a steroid. His hiccups were treated with metoclopramide, but it had little effect, and hiccups only subsided gradually after the disappearance of erosions. His hiccups relapsed transiently with vomiting, and then resolved completely. Elevation of the CF titer after 2 weeks confirmed the diagnosis of herpes zoster. This condition should be considered in patients with unilateral sore throat and intractable hiccups, and treatment with acyclovir should be provided.
authors.affiliation: Department of Otorhinolaryngology, Kobe Japanpost Hospital, Kamitsutsui-dori, Chuo-ku, Japan. smorinakaent@yahoo.co.jp
authors.forename: Setsuko
authors.initials: S
authors.lastname: Morinaka
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D000284:Administration, Oral; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000998:Antiviral Agents / Q000008:administration & dosage; D003967:Diarrhea / Q000139:chemically induced; D004487:Edema / Q000821:virology; D006562:Herpes Zoster / Q000150:complications / Q000188:drug therapy; D006606:Hiccup / Q000821:virology*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000031:analogs & derivatives; D007262:Infusions, Intravenous; D007820:Laryngeal Mucosa / Q000821:virology; D007827:Laryngitis / Q000150:complications* / Q000821:virology*; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use; D019233:Retreatment; D000077483:Valacyclovir; D014633:Valine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives
chemical_list: D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D014633:Valine; D008787:Metoclopramide; C007133:hydrocortisone hemisuccinate; D000077483:Valacyclovir; D006854:Hydrocortisone; D000212:Acyclovir