title: Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata.
abstract: Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A-E (1-5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR ((1)H, (13)C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1-5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.
authors.affiliation: Institut fur Pharmazeutische Biologie and Biotechnologie, Heinrich-Heine-Universitat Dusseldorf, Dusseldorf, Germany.
authors.forename: Yao
authors.initials: Y
authors.lastname: Wang
authors.forename: RuAngelie
authors.initials: R
authors.lastname: Edrada-Ebel
authors.forename: Nanzad
authors.initials: N
authors.lastname: Tsevegsuren
authors.forename: Jandirk
authors.initials: J
authors.lastname: Sendker
authors.forename: Manfred
authors.initials: M
authors.lastname: Braun
authors.forename: Victor
authors.initials: V
authors.lastname: Wray
authors.forename: Wenhan
authors.initials: W
authors.lastname: Lin
authors.forename: Peter
authors.initials: P
authors.lastname: Proksch
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D000077185:Resveratrol; D031186:Scorzonera / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D010851:Picrates; D013267:Stilbenes; C004931:1,1-diphenyl-2-picrylhydrazyl; D000077185:Resveratrol