[Study of determination method for heavy metals and harmful elements residues in four traditional Chinese medicine injections].
Methods for determination of heavy metals and harmful residues in traditional Chinese medicine injection were established. Graphite furnace atomic absorption spectrometry was used for determination of lead, cadmium and copper, atomic fluorescence spectrometry for arsenic and mercury. The preprocessing method was optimized. The average recoveries of 5 elements were between 91% and 112% while the precisions were less than 2%. The determination limit of lead, cadmium, copper, arsenic and mercury were 0.28, 0.014, 0.49, 0.19, 0.061 microg x L(-1), respectively. The proposed method was simple, sensitive, accurate and reliable, and could be used widely.
Nie
Li-xing
LX
National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China. nielixing@163.com
Jin
Hong-yu
HY
Wang
Gang-li
GL
Tian
Jin-gai
JG
Lin
Rui-chao
RC
D001151:Arsenic / Q000032:analysis; D002104:Cadmium / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007854:Lead / Q000032:analysis; D008628:Mercury / Q000032:analysis; D019216:Metals, Heavy / Q000032:analysis*; D013054:Spectrophotometry, Atomic / Q000379:methods*
D004365:Drugs, Chinese Herbal; D019216:Metals, Heavy; D002104:Cadmium; D007854:Lead; D008628:Mercury; D001151:Arsenic