title: Frosted branch angiitis with undiagnosed Hodgkin lymphoma.
abstract: OBJECTIVE
  To report the case of a patient with bilateral frosted branch angiitis and undiagnosed Hodgkin lymphoma.
  
  
  METHODS
  Review of clinical history, laboratory findings, histology of supraclavicular lymph node biopsy, and follow-up.
  
  
  RESULTS
  A 22-year-old man presented with a sudden, bilateral visual loss. Fundus examination and fluorescein angiography disclosed a bilateral frosted branch angiitis that was dramatically responsive to systemic corticosteroid therapy. Laboratory tests were unremarkable but radiologic studies showed extensive mediastinal and supraclavicular lymphadenopathy. A supraclavicular lymph node biopsy led to the diagnosis of nodular sclerosis Hodgkin lymphoma.
  
  
  CONCLUSIONS
  The occurrence of frosted branch angiitis in combination with classical Hodgkin lymphoma, although possibly coincidental, raises the possibility of a paraneoplastic syndrome. Thus, we suggest that, for patients with frosted branch angiitis, Hodgkin lymphoma should be considered in the diagnostic workup.
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Universitaire de Liège, Liège - Belgium. minhtrihua@gmail.com
authors.forename: Minh-Tri
authors.initials: MT
authors.lastname: Hua
authors.forename: Pierre
authors.initials: P
authors.lastname: Blaise
authors.forename: Laurence
authors.initials: L
authors.lastname: De Leval
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Rakic
mesh_terms: D000284:Administration, Oral; D001706:Biopsy; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000175:diagnosis*; D006801:Humans; D007262:Infusions, Intravenous; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D031300:Retinal Vasculitis / Q000175:diagnosis*; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone