title: Doppler echocardiography of 240 normal Carpentier-Edwards Duraflex porcine mitral bioprostheses: a comprehensive assessment including time velocity integral ratio and prosthesis performance index.
abstract: Normal Doppler-derived echocardiographic data for Carpentier-Edwards Duraflex (Edwards Lifesciences, Irvine, CA) porcine bioprosthesis function in the mitral position are limited to 2 small series that did not include all Doppler-derived variables. The purpose of this study was to provide a comprehensive Doppler echocardiographic assessment of normal Carpentier-Edwards Duraflex mitral bioprosthesis function in a large number of patients assessed in the early postoperative phase. All of the important Doppler-derived hemodynamic variables reported to date were used. All patients had either a mitral valve prosthesis time velocity integral to left ventricular outflow tract time velocity integral ratio < 3.9 or an E velocity < 2.8. The pressure half-time was < 130 msec in all patients. Nearly all patients (97%) had an E velocity < 2.8 msec and a mitral valve prosthesis time velocity integral to left ventricular outflow tract time velocity integral ratio < 3.9 regardless of bioprosthesis size, left ventricular function, heart rate, hemoglobin, or hematocrit. With increasing bioprosthesis size, effective orifice area significantly increased, whereas the prosthesis performance index significantly decreased.
authors.affiliation: Division of Cardiovascular Diseases, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Lori A
authors.initials: LA
authors.lastname: Blauwet
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Malouf
authors.forename: Heidi M
authors.initials: HM
authors.lastname: Connolly
authors.forename: David O
authors.initials: DO
authors.lastname: Hodge
authors.forename: Katie N
authors.initials: KN
authors.lastname: Evans
authors.forename: Regina M
authors.initials: RM
authors.lastname: Herges
authors.forename: Thoralf M
authors.initials: TM
authors.lastname: Sundt
authors.forename: Fletcher A
authors.initials: FA
authors.lastname: Miller
mesh_terms: D000465:Algorithms; D000818:Animals; D001705:Bioprosthesis; D015150:Echocardiography, Doppler / Q000379:methods*; D019544:Equipment Failure Analysis / Q000379:methods*; D006350:Heart Valve Prosthesis; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000601:surgery*; D019919:Prosthesis Implantation / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine