title: Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography.
abstract: The purpose of this study was to investigate the effect of image quality on retinal nerve fiber layer (RNFL) and retinal thickness measurements obtained using three commercially available spectral domain-optical coherence tomographers (SD-OCT). Subjectively determined good, medium and poor quality images were obtained from four healthy and one glaucoma suspect eyes. RNFL and retinal thickness measurements were compared as a function of image quality. Results indicate that when image quality is within the range specified as acceptable by SD-OCT manufacturers, RNFL and retinal thickness measurements are comparable.
authors.affiliation: Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, La Jolla CA. 92093-0946 , USA.
authors.forename: Madhusudhanan
authors.initials: M
authors.lastname: Balasubramanian
authors.forename: Christopher
authors.initials: C
authors.lastname: Bowd
authors.forename: Gianmarco
authors.initials: G
authors.lastname: Vizzeri
authors.forename: Robert N
authors.initials: RN
authors.lastname: Weinreb
authors.forename: Linda M
authors.initials: LM
authors.lastname: Zangwill
mesh_terms: D000328:Adult; D005901:Glaucoma / Q000473:pathology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D011786:Quality Control; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data