title: Multiple aseptic liver abscesses as the initial manifestation of Crohn's disease: report of a case.
abstract: Aseptic liver abscesses preceding the diagnosis of Crohn's disease are extremely rare. We report a patient with multiple liver abscesses that yielded negative microbiologic investigation and failed to develop full remission under antibiotic therapy. Diagnosis of Crohn's disease of small and large bowel was later established and she was started on sulfasalazine and azathioprine with total regression of the hepatic abscesses. This case illustrates the rare possibility of aseptic liver abscesses as an initial manifestation of Crohn's disease, which could be interpreted in the light of recent data on aberrant homing of gut T memory/effector lymphocytes in the liver.
authors.affiliation: Department of Medicine 2, University Hospital Santa Maria / Faculty of Medicine of Lisbon, Lisbon, Portugal.
authors.forename: Raed
authors.initials: R
authors.lastname: Zakout
authors.forename: Marina
authors.initials: M
authors.lastname: Fonseca
authors.forename: João Meneses
authors.initials: JM
authors.lastname: Santos
authors.forename: António
authors.initials: A
authors.lastname: Marques
authors.forename: Isabel
authors.initials: I
authors.lastname: Távora
authors.forename: Emília
authors.initials: E
authors.lastname: Oliveira
authors.forename: Carlos
authors.initials: C
authors.lastname: Ferreira
authors.forename: Rui M M
authors.initials: RM
authors.lastname: Victorino
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008100:Liver Abscess / Q000150:complications*