title: [Investigation on degeneration of outer hair cells in guinea pig].
abstract: OBJECTIVE
  To investigate the degeneration mechanics of outer hair cells in guinea pig.
  
  
  METHODS
  The mechanics of outer hair cells isolated by enzyme were observed under inverted microscope for 6-8 h continuously.
  
  
  RESULTS
  Over half of living outer hair cells could keep good conditions in 6 hours. During the degeneration there was always a longitudinal fold line from tip to base. Presence or absence of calcium, as well as lossing of stereociliary bundle, couldn't change the conditions of out hair cells.
  
  
  CONCLUSIONS
  Neither calcium nor stereociliary bundle is the decisive cause in keeping outer hair cells alive, and its degeneration may be basically related with something surrounding the cell.
authors.affiliation: Department of Otolaryngology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Xixun
authors.initials: X
authors.lastname: Kang
authors.forename: Weijia
authors.initials: W
authors.lastname: Kong
authors.forename: Wanrong
authors.initials: W
authors.lastname: Li
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Zeng
authors.forename: Song
authors.initials: S
authors.lastname: Zhnag
authors.forename: Changkai
authors.initials: C
authors.lastname: Guo
authors.forename: Xiang
authors.initials: X
authors.lastname: Huang
mesh_terms: D000818:Animals; D002118:Calcium; D002478:Cells, Cultured; D003051:Cochlea / Q000166:cytology* / Q000473:pathology*; D003470:Culture Media; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000166:cytology*
chemical_list: D003470:Culture Media; D002118:Calcium