title: Mediterranean spotted fever with encephalitis.
abstract: Rickettsia conorii infection is endemic in the Mediterranean basin, where it is known as Mediterranean spotted fever, also known as Boutonneuse fever and Marseilles fever. We report the case of a 66-year-old diabetic man who presented a severe form of the disease, complicated by acute renal failure, thrombocytopenia and encephalitis. Diagnosis was confirmed by indirect immunofluorescence assay. Despite appropriate treatment, severe neurological sequelae have remained. Medical literature on encephalitis caused by R. conorii is also reviewed.
authors.affiliation: Faculty of Medicine (University of Granada), Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Aliaga
authors.affiliation: Faculty of Medicine (University of Granada), Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: Sánchez-Blázquez
authors.affiliation: Service of Microbiology, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Rodríguez-Granger
authors.affiliation: Service of Microbiology, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Sampedro
authors.affiliation: Faculty of Medicine (University of Granada), Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Orozco
authors.affiliation: Service of Radiology, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain.
authors.forename: Jorge
authors.initials: J
authors.lastname: Pastor
mesh_terms: D000368:Aged; D001907:Boutonneuse Fever / Q000150:complications*; D001921:Brain / Q000473:pathology; D048909:Diabetes Complications / Q000382:microbiology; D004660:Encephalitis / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D051437:Renal Insufficiency / Q000150:complications