title: First total synthesis of the whole series of the antiostatins A and B.
abstract: The first synthesis of the whole antiostatin family is described by using an iron-mediated carbazole synthesis, regioselective nitration at C-4 and establishing 5-isobutyl-1-nitrobiuret as a reagent for introduction of the antiostatin B side chain at C-4.
authors.affiliation: Department Chemie, Technische Universität Dresden, Bergstrasse 66, 01069, Dresden, Germany.
authors.forename: Kerstin E
authors.initials: KE
authors.lastname: Knott
authors.forename: Stefan
authors.initials: S
authors.lastname: Auschill
authors.forename: Anne
authors.initials: A
authors.lastname: Jäger
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Knölker
mesh_terms: D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007501:Iron / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D002227:Carbazoles; C540617:antiostatin A1; C540618:antiostatin B2; C041514:carbazole; D007501:Iron