[Diffuse large B-cell lymphoma presenting with hypoglossal nerve palsy and great occipital neuralgia].
A 74-year-old man was hospitalized with hypoglossal nerve paralysis and severe great occipital neuralgia. Enhanced MRI of the head showed tumor on the left petrous bone, which compressed the medulla oblongata. Soluble IL-2 receptor was elevated and malignant lymphoma was clinically diagnosed. PET-CT demonstrated a single hot spot on the spleen. After radiation therapy to the lesion on the petrous bone, splenectomy was performed. Pathological findings established a diagnosis of diffuse large B-cell lymphoma. After chemotherapy consisting of rituximab and THP-COP, complete remission was achieved.
Kanai
Yoshitaka
Y
Department of Internal Medicine, PL General Hospital, Japan.
Matsuda
Mitsuhiro
M
Iwanaga
Takayuki
T
Hashimoto
Shigeo
S
Maeda
Yasuhiro
Y
Kanamaru
Akihisa
A
Itagaki
Nobuo
N
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D003131:Combined Modality Therapy; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000209:etiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D009378:Neoplasms, Multiple Primary; D009437:Neuralgia / Q000209:etiology*; D009777:Occipital Bone / Q000294:innervation*; D010579:Petrous Bone; D015375:Receptors, Interleukin-2 / Q000097:blood; D012074:Remission Induction; D012888:Skull Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013160:Splenic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000628:therapy
D014408:Biomarkers, Tumor; D015375:Receptors, Interleukin-2