[Prophylaxis of postoperative endophthalmitis with intracameral cefuroxime: a five years' experience].
OBJECTIVE
To present the outcomes of prophylaxis of postoperative endophthalmitis following cataract surgery with intracameral Cefuroxime.


METHODS
A retrospective study was done on 4281 eyes that underwent cataract surgery from October 2003 to September 2008. All patients underwent phacoemulsification cataract surgery. All cases received an injection of 0.1 ml intracameral Cefuroxime (1 mg) at the end of surgery except those patients allergic to penicillin and cephalosporin until September 2007 and thereafter only those with demonstrated allergy to cefuroxime.


RESULTS
The rate of postoperative endophthalmitis was 0.11% (5 cases). Four of them had a positive culture. We found no evidence of clinical ocular toxicity.


CONCLUSIONS
Intracameral cefuroxime works very well for reducing the incidence of postoperative endophthalmitis. It appears safe to use and is easy to prepare.
Díez
M R
MR
Hospital Universitario de Getafe, Madrid, España. mdiez.hugf@salud.madrid.org
De la Rosa
G
G
Pascual
R
R
Girón
C
C
Arteta
M
M
D000867:Anterior Chamber; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D002444:Cefuroxime / Q000008:administration & dosage* / Q000627:therapeutic use; D003354:Corynebacterium Infections / Q000209:etiology; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D009877:Endophthalmitis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D015994:Incidence; D007267:Injections; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000209:etiology; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D014821:Vitrectomy
D000900:Anti-Bacterial Agents; D002444:Cefuroxime