p53-dependent apoptosis in response to spindle damage is linked to loss of Bub1.
Beeharry
Neil
N
Fox Chase Cancer Center, Philadelphia, PA, USA. Neil.Beeharry@fccc.edu
Yen
Tim J
TJ
D017209:Apoptosis / Q000502:physiology*; D045325:HCT116 Cells; D006801:Humans; D017346:Protein Serine-Threonine Kinases / Q000172:deficiency* / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; C584277:BUB1 protein, human; C090464:Bub1 spindle checkpoint protein; D017346:Protein Serine-Threonine Kinases