A preliminary study to examine the effects of aerobic and therapeutic (nonaerobic) exercise on cardiorespiratory fitness and coronary risk reduction in stroke survivors.
OBJECTIVE
To compare the effects of 3 different exercise training regimens on cardiorespiratory fitness and coronary risk factor reduction in subjects with unilateral stroke.


METHODS
A cluster assignment by residential location repeated-measures design.


METHODS
University-based medical center.


METHODS
Fifty-five subjects with unilateral ischemic stroke were assigned to the following groups: intensity (n=18), duration (n=19), and therapeutic exercise (n=18).


METHODS
A 14-week intervention with subjects randomized to 1 of 3 interventions: (1) moderate intensity, shorter duration (MISD) exercise (gradually increasing exercise intensity while keeping exercise duration constant at 30 min), (2) low-intensity, longer duration (LILD) exercise (gradually increasing duration to 60 min while keeping exercise intensity constant), or (3) conventional therapeutic exercise (TE) consisting mainly of strength, balance, and range of motion activities. All groups exercised 3 days per week.


METHODS
Peak oxygen consumption (VO2peak), submaximal oxygen consumption (VO2), lipid panel, and resting blood pressure.


RESULTS
The MISD group attained more favorable effects on systolic (P<.04) and diastolic blood pressure (P<.002) and total cholesterol (TC) (P<.036) compared with LILD and TE groups. Both MISD (P<.029) and LILD (P<.045) showed significant reductions in triglycerides compared with TE (P<.029). There was no significant change in VO2peak and submaximal VO2 in any of the groups.


CONCLUSIONS
Overall, both MISD and LILD conditions achieved greater clinical and significant gains in coronary risk reduction compared with TE.
Rimmer
James H
JH
Department of Disability and Human Development, University of Illinois, Chicago, IL 60608-6904, USA.
Rauworth
Amy E
AE
Wang
Edward C
EC
Nicola
Terry L
TL
Hill
Bernadette
B
D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control; D005080:Exercise Test; D005081:Exercise Therapy / Q000145:classification* / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology / Q000534:rehabilitation; D010101:Oxygen Consumption; D010809:Physical Fitness; D010865:Pilot Projects; D040242:Risk Reduction Behavior; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation