title: [Necrosis of the glans penis: a complication of an injection of buprenorphin in a opioid abuser].
abstract: Necrosis of the penis glans is commonly described after circumcision or strangulation. We report the case of a patient, opioid abuser, who presented an isolated glans necrosis after an injection of buprenorphin. The buprenorphin (Subutex) is a sublingual partial mu-opioid agonist used for the treatment of heroin dependance. Its intravenous or subcutaneous abuse is associated with local infection. The patient require a surgical intervention. After the failure of a mucosal graft, a soft skin graft was done.
authors.affiliation: Service de chirurgie viscérale et vasculaire, hôpital d'instruction-des-Armées Sainte-Anne, boulevard Sainte-Anne, 83000 Toulon, France. Emmanuelhornez@free.fr
authors.forename: E
authors.initials: E
authors.lastname: Hornez
authors.forename: J
authors.initials: J
authors.lastname: Laroche
authors.forename: T
authors.initials: T
authors.lastname: Monchal
authors.forename: S
authors.initials: S
authors.lastname: Bourgouin
authors.forename: P
authors.initials: P
authors.lastname: Riviere
authors.forename: R
authors.initials: R
authors.lastname: Fournier
authors.forename: E
authors.initials: E
authors.lastname: Dantzer
mesh_terms: D000328:Adult; D002047:Buprenorphine / Q000008:administration & dosage / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000534:rehabilitation; D005500:Follow-Up Studies; D006556:Heroin Dependence / Q000534:rehabilitation; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D009292:Narcotic Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D009336:Necrosis; D010413:Penis / Q000187:drug effects* / Q000601:surgery; D012086:Reoperation; D016038:Skin Transplantation; D013530:Surgical Wound Infection / Q000209:etiology / Q000601:surgery; D014945:Wound Healing / Q000502:physiology
chemical_list: D009292:Narcotic Antagonists; D002047:Buprenorphine