title: Ruthenium-based metallacrown complexes for the selective detection of lithium ions in water and in serum by fluorescence spectroscopy.
abstract: Fluorescent dihydroxypyridine ligands were prepared by attaching pyrene-, dansyl-, and methoxycoumarin-fluorophores via dimethyleneamine linkers. The reaction of these ligands with [(p-cymene)RuCl(2)](2) or [(C(6)H(5)CH(2)NMe(2)H)RuCl(2)](2)Cl(2) resulted in the formation of 12-metallacrown-3 complexes, which possess strong affinity for lithium ions. By a judicious choice of the fluorophore and the arene pi-ligand, a macrocycle was obtained that could be used in aqueous solution to selectively and quantitatively detect lithium ions by fluorescence spectroscopy.
authors.affiliation: Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Rochat
authors.forename: Zacharias
authors.initials: Z
authors.lastname: Grote
authors.forename: Kay
authors.initials: K
authors.lastname: Severin
mesh_terms: D006801:Humans; D007477:Ions / Q000032:analysis; D008024:Ligands; D008094:Lithium / Q000032:analysis*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry*
chemical_list: D007477:Ions; D008024:Ligands; D009942:Organometallic Compounds; D014867:Water; D012428:Ruthenium; D008094:Lithium