title: The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance.
abstract: Bactericidal activity of traditional titanium dioxide (TiO2) photocatalyst is effective only upon irradiation by ultraviolet light, which restricts the potential applications of TiO2 for use in our living environments. Recently carbon-containing TiO2 was found to be photoactive at visible-light illumination that affords the potential to overcome this problem; although, the bactericidal activity of these photocatalysts is relatively lower than conventional disinfectants. Evidenced from scanning electron microscopy and confocal Raman spectral mapping analysis, we found the interaction with bacteria was significantly enhanced in these anatase/rutile mixed-phase carbon-containing TiO2. Bacteria-killing experiments indicate that a significantly higher proportion of all tested pathogens including Staphylococcus aureus, Shigella flexneri and Acinetobacter baumannii, were eliminated by the new nanoparticle with higher bacterial interaction property. These findings suggest the created materials with high bacterial interaction ability might be a useful strategy to improve the antimicrobial activity of visible-light-activated TiO2.
authors.affiliation: Department of Physics, National Dong-Hwa University, Hualien, Taiwan. clcheng@mail.ndhu.edu.tw
authors.forename: Chia-Liang
authors.initials: CL
authors.lastname: Cheng
authors.forename: Der-Shan
authors.initials: DS
authors.lastname: Sun
authors.forename: Wen-Chen
authors.initials: WC
authors.lastname: Chu
authors.forename: Yao-Hsuan
authors.initials: YH
authors.lastname: Tseng
authors.forename: Han-Chen
authors.initials: HC
authors.lastname: Ho
authors.forename: Jia-Bin
authors.initials: JB
authors.lastname: Wang
authors.forename: Pei-Hua
authors.initials: PH
authors.lastname: Chung
authors.forename: Jiann-Hwa
authors.initials: JH
authors.lastname: Chen
authors.forename: Pei-Jane
authors.initials: PJ
authors.lastname: Tsai
authors.forename: Nien-Tsung
authors.initials: NT
authors.lastname: Lin
authors.forename: Mei-Shiuan
authors.initials: MS
authors.lastname: Yu
authors.forename: Hsin-Hou
authors.initials: HH
authors.lastname: Chang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000472:pathogenicity; D002384:Catalysis; D024881:Drug Resistance, Bacterial; D006801:Humans; D008027:Light; D053768:Metal Nanoparticles / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010777:Photochemistry; D013059:Spectrum Analysis, Raman; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; C009495:titanium dioxide; D014025:Titanium