title: Prevalence of Panton-Valentine leukocidin genes in methicillin-resistant Staphylococcus aureus isolates phenotypically consistent with community-acquired MRSA, 1999-2007, Vienna General Hospital.
abstract: The purpose of this study was to investigate methicillin-resistant Staphylococcus aureus (MRSA) isolates with antibiotic resistance restricted to beta-lactam antibiotics and variable resistance to fusidic acid for the presence of Panton-Valentine leukocidin (PVL) genes. Our data show that the selected resistance pattern is found rarely among MRSA isolates in our hospital, but it appears that this phenotype consistent with typical community-acquired (ca) MRSA is indicative of PVL-positive MRSA.
authors.affiliation: Division of Hospital Hygiene, Clinical Institute of Hygiene and Medical Microbiology, Medical University Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
authors.forename: C C
authors.initials: CC
authors.lastname: Bauer
authors.forename: P
authors.initials: P
authors.lastname: Apfalter
authors.forename: F
authors.initials: F
authors.lastname: Daxboeck
authors.forename: N
authors.initials: N
authors.lastname: Bachhofner
authors.forename: M
authors.initials: M
authors.lastname: Stadler
authors.forename: A
authors.initials: A
authors.lastname: Blacky
authors.forename: M
authors.initials: M
authors.lastname: Diab-Elschahawi
authors.forename: O
authors.initials: O
authors.lastname: Assadian
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001317:Austria; D001426:Bacterial Proteins / Q000235:genetics*; D001427:Bacterial Toxins / Q000235:genetics*; D017714:Community-Acquired Infections / Q000382:microbiology*; D005098:Exotoxins / Q000235:genetics*; D006769:Hospitals, General; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D013203:Staphylococcal Infections / Q000382:microbiology*; D037521:Virulence Factors / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors; D047090:beta-Lactams