Population genetic models of duplicated genes.
Various population genetic models of duplicated genes are introduced. The problems covered in this review include the fixation process of a duplicated copy, copy number polymorphism, the fates of duplicated genes and single nucleotide polymorphism in duplicated genes. Because of increasing evidence for concerted evolution by gene conversion, this review introduces recently developed gene conversion models. In the first half, models assuming independent evolution of duplicated genes are introduced, and then the effect of gene conversion is considered in the second half.
Innan
Hideki
H
Graduate University for Advanced Studies, Hayama, Kanagawa, 240-0193, Japan. innan_hideki@soken.ac.jp
D000818:Animals; D001483:Base Sequence; D019143:Evolution, Molecular; D005785:Gene Conversion / Q000235:genetics; D018628:Gene Dosage / Q000235:genetics; D020440:Gene Duplication; D020131:Genes, Duplicate / Q000235:genetics*; D006801:Humans; D008957:Models, Genetic; D011110:Polymorphism, Genetic