title: Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis.
abstract: The Enterococcus faecalis class IIa bacteriocin MC4-1 encoded by the sex pheromone-responding, multiple-antibiotic resistance plasmid pAMS1 exhibits "siblicidal" (sibling-killing) activity under certain conditions. Stabs of plasmid-containing cells on solid medium containing lawns of bacteria of the same (plasmid-containing) strain give rise to zones of inhibition. If the plasmid-containing host also produces gelatinase, bacteriocin cannot be detected.
authors.affiliation: Department of Cariology, Restorative Sciences & Endodontics, School of Dentistry, The University of Michigan, 1011 N. University Ave., Ann Arbor, MI 48109-1078, USA. csedgley@umich.edu
authors.forename: Christine M
authors.initials: CM
authors.lastname: Sedgley
authors.forename: Don B
authors.initials: DB
authors.lastname: Clewell
authors.forename: Susan E
authors.initials: SE
authors.lastname: Flannagan
mesh_terms: D000900:Anti-Bacterial Agents / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000494:pharmacology*; D001430:Bacteriocins / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000235:genetics / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000235:genetics; D018093:Gelatinases / Q000378:metabolism; D005798:Genes, Bacterial; D050296:Microbial Viability; D010957:Plasmids
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D018093:Gelatinases