Identification of a novel HLA-A allele, A*3120.
A novel human leukocyte antigen (HLA)-A allele, HLA-A*3120, was first identified in a National Marrow Donor Program (NMDP) donor. The A*3120 allele resulted from a single nucleotide substitution (T to G) at codon 92 of exon 3 of A*310102. The substitution caused an amino acid change (serine to alanine). This novel allele was also seen in two other unrelated NMDP donors.
Chang
Y
Y
Department of Pathology and Laboratory Medicine, All Children's Hospital, St Petersburg, FL 33701, USA. changy@allkids.org
Pascual
C J
CJ
Alonzo
P
P
Chamizo
A
A
D000483:Alleles; D001483:Base Sequence; D005091:Exons; D005838:Genotype; D015234:HLA-A Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens; C540896:HLA-A*31:20 antigen