Hypokalemic paralysis and megaloblastic anaemia in Laurence-Moon-Bardet-Biedl syndrome.
Laurence-Moon-Bardet-Biedl syndrome is a rare, genetically heterogeneous autosomal recessive disorder, characterized by progressive retinal dystrophy, polydactyly, obesity, hypogonadism, mental retardation, and renal dysfunction. Other manifestations include diabetes mellitus, heart disease, hepatic fibrosis and neurological features. Herein, 2 patients with Laurence-Moon-Bardet-Biedl syndrome are described, who had features of persistent hypokalemia and megaloblastic anemia.
Abbasi
Amanullah
A
Ward-7, Jinnah Postgraduate Medical Centre, Karachi. draman_ullah2000@yahoo.com
Butt
Nazish
N
Sultan
Baseer
B
Munir
S M
SM
D000293:Adolescent; D000328:Adult; D000749:Anemia, Megaloblastic / Q000150:complications*; D020788:Bardet-Biedl Syndrome / Q000150:complications*; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000150:complications*; D008297:Male