title: Health-related quality of life in obese children and adolescents.
abstract: OBJECTIVE
  This review addresses the effect of overweight and obese weight status on pediatric health-related quality of life (HRQOL).
  
  
  METHODS
  Web of Science, Medline, CINAHL, Cochrane Library, EMBASE, AMED and PubMed were searched for peer-reviewed studies in English reporting HRQOL and weight status in youth (<21 years), published before March 2008.
  
  
  RESULTS
  Twenty-eight articles were identified. Regression of HRQOL against body mass index (BMI) using pooled data from 13 studies utilizing the Pediatric Quality of Life Inventory identified an inverse relationship between BMI and pediatric HRQOL (r=-0.7, P=0.008), with impairments in physical and social functioning consistently reported. HRQOL seemed to improve with weight loss, but randomized controlled trials were few and lacked long-term follow-up.
  
  
  CONCLUSIONS
  Little is known about the factors associated with reduced HRQOL among overweight or obese youth, although gender, age and obesity-related co-morbidities may play a role. Few studies have examined the differences in HRQOL between community and treatment-seeking samples. Pooled regressions suggest pediatric self-reported HRQOL can be predicted from parent proxy reports, although parents of obese youths tend to perceive worse HRQOL than children do about themselves. Thus, future research should include both pediatric and parent proxy perspectives.
authors.affiliation: Australian Technology Network Centre for Metabolic Fitness, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
authors.forename: M D
authors.initials: MD
authors.lastname: Tsiros
authors.forename: T
authors.initials: T
authors.lastname: Olds
authors.forename: J D
authors.initials: JD
authors.lastname: Buckley
authors.forename: P
authors.initials: P
authors.lastname: Grimshaw
authors.forename: L
authors.initials: L
authors.lastname: Brennan
authors.forename: J
authors.initials: J
authors.lastname: Walkley
authors.forename: A P
authors.initials: AP
authors.lastname: Hills
authors.forename: P R C
authors.initials: PR
authors.lastname: Howe
authors.forename: A M
authors.initials: AM
authors.lastname: Coates
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D009765:Obesity / Q000517:prevention & control / Q000523:psychology*; D050177:Overweight / Q000523:psychology; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*