Antibacterial triterpenes from the threatened wood-decay fungus Fomitopsis rosea.
From a biologically active extract from the fungus Fomitopsis rosea, two new lanostane triterpenes were isolated, 3alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid C 1 and 3alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid 2, along with three known triterpenes, 3-5, and the epidioxy sterol derivative 6. The structures of the compounds were elucidated based on their spectral properties. All triterpenes demonstrated antibacterial activity against S. aureus but possessed no antiradical activity against DPPH radicals.
Popova
Milena
M
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Trusheva
Boryana
B
Gyosheva
Melania
M
Tsvetkova
Iva
I
Bankova
Vassya
V
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002788:Cholesterol Esters / Q000302:isolation & purification* / Q000494:pharmacology; D055453:Coriolaceae / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
C543231:3alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid; C543232:3alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid; D000900:Anti-Bacterial Agents; D002788:Cholesterol Esters; D014315:Triterpenes; C421424:epidioxysterol