title: Ten reasons to exclude viruses from the tree of life.
abstract: When viruses were discovered, they were accepted as missing links between the inert world and living organisms. However, this idea was soon abandoned as information about their molecular parasitic nature accumulated. Recently, the notion that viruses are living organisms that have had a role in the evolution of some essential features of cells has experienced a renaissance owing to the discovery of unusually large and complex viruses that possess typical cellular genes. Here, we contend that there is strong evidence against the notion that viruses are alive and represent ancient lineages of the tree of life.
authors.affiliation: Unité d'Ecologie, Systématique et Evolution, UMR CNRS 8,079, Université Paris-Sud, bâtiment 360, 91405 Orsay Cedex, France. david.moreira@u-psud.fr
authors.forename: David
authors.initials: D
authors.lastname: Moreira
authors.forename: Purificación
authors.initials: P
authors.lastname: López-García
mesh_terms: D004279:DNA, Viral / Q000235:genetics; D019143:Evolution, Molecular; D019369:Life; D000069497:Origin of Life; D014780:Viruses / Q000145:classification* / Q000235:genetics
chemical_list: D004279:DNA, Viral