title: Chronic Arsenic poisoning.
abstract: Chronic Arsenic Toxicity may have varied clinical presentations ranging from non-cancerous manifestations to malignancy of skin and different internal organs. Dermal lesions such as hyper pigmentation and hyperkeratosis, predominantly over palms and soles are diagnostic of Chronic Arsenicosis. We report two cases from a family living in Sukkur who presented with classical skin lesions described in Chronic Arsenicosis. The urine, nail and hair samples of these patients contained markedly elevated levels of arsenic. Also the water samples from their household and the neighbouring households were found to have alarming levels of inorganic Arsenic.
authors.affiliation: Medical Unit II, Jinnah Postgraduate Medical Centre, Pesir.
authors.forename: Tasnim
authors.initials: T
authors.lastname: Ahsan
authors.forename: Kaneez
authors.initials: K
authors.lastname: Zehra
authors.forename: Alia
authors.initials: A
authors.lastname: Munshi
authors.forename: Samiah
authors.initials: S
authors.lastname: Ahsan
mesh_terms: D000293:Adolescent; D000328:Adult; D001151:Arsenic / Q000652:urine*; D020261:Arsenic Poisoning; D006197:Hair / Q000737:chemistry; D006801:Humans; D008297:Male; D009262:Nails / Q000737:chemistry; D010154:Pakistan; D014873:Water Pollutants / Q000506:poisoning*; D014881:Water Supply / Q000032:analysis*
chemical_list: D014873:Water Pollutants; D001151:Arsenic