title: Cardiovascular risk factors characteristic for the metabolic syndrome in adult patients with type 1 diabetes.
abstract: The prevalence rate and clinical significance of the metabolic syndrome in type 1 diabetic patients are not well established. The aim of this study was to estimate the prevalence rate of the metabolic syndrome in adult patients with type 1 diabetes. Patients with type 1 diabetes (n=533; age: 35.6+/-11.6 years; duration of diabetes: 18.0+/-11.1 years; x+/-SD) were consecutively enrolled from 11 diabetes outpatient departments. Data on medical history, actual treatment, anthropometric and laboratory parameters as well as actual blood pressure were registered while eating habits and physical activity were evaluated by standardized questionnaires. The prevalence rate of the metabolic syndrome according to the ATP-III criteria was 31.1% (29.7% in men, 32.7% in women; p>0.05). Using the IDF criteria a higher overall prevalence rate of the metabolic syndrome (36.2%; [32,8% in men, 39.4% in women; p>0.05]) was observed. Comparing type 1 diabetic patients to the general population, the prevalence rate of the metabolic syndrome proved to be significantly higher in each age-group of patients with type 1 diabetes. According to the stepwise logistic regression analysis the metabolic syndrome in type 1 diabetic patients was associated in a decreasing ranking order of significance with waist circumference, serum triglycerides, female gender, antihypertensive medication, HDL-cholesterol, diastolic blood pressure and serum creatinine.
  
  
  CONCLUSIONS
  The metabolic syndrome can frequently be detected and is predominantly associated with higher waist circumference in adult patients with type 1 diabetes in Hungary.
authors.affiliation: Bajcsy-Zsilinszky Hospital, Budapest, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Nádas
authors.forename: Z
authors.initials: Z
authors.lastname: Putz
authors.forename: J
authors.initials: J
authors.lastname: Fövényi
authors.forename: Z
authors.initials: Z
authors.lastname: Gaál
authors.forename: A
authors.initials: A
authors.lastname: Gyimesi
authors.forename: T
authors.initials: T
authors.lastname: Hídvégi
authors.forename: N
authors.initials: N
authors.lastname: Hosszúfalusi
authors.forename: G
authors.initials: G
authors.lastname: Neuwirth
authors.forename: T
authors.initials: T
authors.lastname: Oroszlán
authors.forename: P
authors.initials: P
authors.lastname: Pánczél
authors.forename: G
authors.initials: G
authors.lastname: Széles
authors.forename: G
authors.initials: G
authors.lastname: Vándorfi
authors.forename: G
authors.initials: G
authors.lastname: Winkler
authors.forename: I
authors.initials: I
authors.lastname: Wittmann
authors.forename: G
authors.initials: G
authors.lastname: Jermendy
mesh_terms: D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000150:complications* / Q000453:epidemiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D012307:Risk Factors