[Systemic inflammatory reaction, antiendotoxin immunity and polyorgan insufficiency in patients of the intensive therapy departments].
The connection of C-reactive protein (CRP) and the antiendotoxin immunoglobulins (Ig) levels with lethality of the Intensive Therapy Department (DITH) patients was studied up. In 45 patients after hospitalization there were analyzed the levels of CRP, general and the specific antiendotoxin Ig. In 14 patients, who, suffering polyorgan insufficiency (POI), subsequently died, the CRP content was hightened and the antiendotoxins IgG concentration--reducted. The conclusion was formulated, that systemic inflammatory reaction and POI are connected with bacterial translocation phenomenon. Determination of CRP and the antiendotoxin IgG levels may be used for delineation of a group of the DITH patients owing high risk of POI occurrence and lethality.
Potapov
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D000911:Antibodies, Monoclonal / Q000276:immunology; D002097:C-Reactive Protein / Q000032:analysis; D003422:Critical Care / Q000379:methods*; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D007362:Intensive Care Units; D008070:Lipopolysaccharides / Q000276:immunology*; D009102:Multiple Organ Failure / Q000097:blood / Q000276:immunology* / Q000401:mortality; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D016019:Survival Analysis; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood / Q000276:immunology* / Q000401:mortality
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins; D008070:Lipopolysaccharides; D002097:C-Reactive Protein