[Metabolic syndrome and cerebrovascular disease: evidence in their treatment].
BACKGROUND
Stroke (cerebrovascular disease) is the leading cause of disability and the third of death worldwide. It is considered an age-related disease, although there are several modifiable risk factors, including the simultaneous and frequent combination of obesity, hypertension, dyslipidaemia and elevated fast glucose, which has been labeled the metabolic syndrome; nowadays, it is associated with generalized and brain atherosclerosis.


METHODS
It is analyzed here how both different components of metabolic syndrome and metabolic syndrome itself are important risk factors for suffering stroke, one by one and all grouped together as well. Based on the best available clinical evidence, appropriated medical management strategies are proposed (evidence-based treatment).


CONCLUSIONS
It is proposed a comprehensive medical treatment approach, targeted on the metabolic syndrome trough simultaneous management of individual components; currently, modifications in lifestyle (increasing exercise, weight reduction and diet) are recommended; besides, based on the best available evidence, pharmacological treatment should be considered when necessary.
Rodríguez-Kú
R J
RJ
Departamento de Neurofisiología, Hospital General Regional numero 1, Instituto Mexicano del Seguro Social, Mérida, Yucatán, México. renneuro@hotmail.com
D002561:Cerebrovascular Disorders / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D003920:Diabetes Mellitus / Q000503:physiopathology / Q000628:therapy; D050171:Dyslipidemias / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000503:physiopathology / Q000628:therapy; D024821:Metabolic Syndrome / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D009765:Obesity / Q000150:complications; D012307:Risk Factors