Synthesis and vanilloid receptor (TRPV1) activity of the enantiomers of alpha-fluorinated capsaicin.
Winkler
Margit
M
School of Chemistry and Centre for Biomolecular Sciences, University of St. Andrews, North Haugh, KY16 9ST St. Andrews, UK.
Moraux
Thomas
T
Khairy
Hesham A
HA
Scott
Roderick H
RH
Slawin
Alexandra M Z
AM
O'Hagan
David
D
D000818:Animals; D002211:Capsaicin / Q000138:chemical synthesis / Q000378:metabolism; D017611:Fluorine Compounds / Q000138:chemical synthesis / Q000378:metabolism; D005727:Ganglia, Spinal / Q000166:cytology; D054879:Halogenation; D006801:Humans; D008968:Molecular Conformation; D015394:Molecular Structure; D009474:Neurons / Q000166:cytology / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013237:Stereoisomerism; D050916:TRPV Cation Channels / Q000378:metabolism*
D017611:Fluorine Compounds; D050916:TRPV Cation Channels; C493922:Trpv1 protein, rat; D002211:Capsaicin