title: [Hypopharyngeal cancer: analysis of the evolution and treatment results].
abstract: OBJECTIVE
  Hypopharyngeal carcinoma is an aggressive malignancy usually diagnosed at a late state, thereby resulting in overall poor prognosis and low survival rates for these patients. The purpose of this study is to present the progress and outcomes of patients treated for hypopharyngeal carcinoma at our department.
  
  
  METHODS
  We retrospectively reviewed 89 patients who had been diagnosed with hypopharygeal carcinoma between 1980 and 2005. Most of the tumours were advanced (T3 and T4) and 73 % showed palpable regional metastases at presentation.
  
  
  RESULTS
  The five-year survival rate was 40.7 %. The overall incidence of distant metastases and subsequent primary neoplasms was 7.5 % and 23.5 %, respectively.
  
  
  CONCLUSIONS
  Hypopharyngeal cancer is still the one with the worst prognosis in the head and neck area. The poor survival rate seems to be related primarily to advanced stage disease at presentation and particularly to the status of cervical lymph-node metastases.
authors.affiliation: Servicio Otorrinolaringología, Hospital Universitario Dr. Peset, Valencia, España. fernandoymarina@ono.com
authors.forename: Marina
authors.initials: M
authors.lastname: Carrasco Llatas
authors.forename: Celia
authors.initials: C
authors.lastname: López Mollá
authors.forename: Ramón
authors.initials: R
authors.lastname: Balaguer García
authors.forename: María José
authors.initials: MJ
authors.lastname: Ferrer Ramírez
authors.forename: Fernando
authors.initials: F
authors.lastname: Guallart Doménech
authors.forename: José Enrique
authors.initials: JE
authors.lastname: Estellés Ferriol
authors.forename: Sergio
authors.initials: S
authors.lastname: Fernández Martínez
authors.forename: José
authors.initials: J
authors.lastname: Dalmau Galofre
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate