title: Fatigue and physical activity in older patients with cancer: a six-month follow-up study.
abstract: OBJECTIVE
  To determine the relationship between fatigue and physical activity in older patients with cancer.
  
  
  METHODS
  Targeted analysis using data from a prospective longitudinal study.
  
  
  METHODS
  A cancer care facility in southeastern Ontario, Canada.
  
  
  METHODS
  440 patients, aged 65 years and older, seeking consultation for cancer treatment at a regional cancer clinic for lymphoma or leukemia or lung, breast, genitourinary, head or neck, gastrointestinal, or skin cancers.
  
  
  METHODS
  Self-report questionnaires were mailed to consenting participants and completed at baseline and three and six months after consultation for cancer treatment.
  
  
  METHODS
  Participants rated fatigue and physical activity and reported comorbidities and personal demographic characteristics. Clinical measures of disease and treatment factors were obtained through chart abstraction.
  
  
  RESULTS
  Fatigue was the most prevalent symptom reported. Higher fatigue was associated with lower physical activity levels. Physical activity level significantly predicted fatigue level, regardless of age.
  
  
  CONCLUSIONS
  Physical activity level is a modifiable factor significantly predicting cancer-related fatigue at three and six months following consultation for cancer treatment. The results suggest that physical activity may reduce fatigue in older patients with cancer.
  
  
  CONCLUSIONS
  Physical activity interventions should be developed and tested in older patients with cancer.
authors.affiliation: School of Nursing, Queen's University, Kingston, Canada. luctkarm@kgh.kari.net
authors.forename: Marian
authors.initials: M
authors.lastname: Luctkar-Flude
authors.forename: Dianne
authors.initials: D
authors.lastname: Groll
authors.forename: Kirsten
authors.initials: K
authors.lastname: Woodend
authors.forename: Joan
authors.initials: J
authors.lastname: Tranmer
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D002173:Cancer Care Facilities; D015897:Comorbidity; D015444:Exercise / Q000502:physiology / Q000523:psychology; D005221:Fatigue / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016014:Linear Models; D008297:Male; D015999:Multivariate Analysis; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D015404:Nursing Methodology Research; D009864:Ontario; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires