Micropeptins from the freshwater cyanobacterium Microcystis aeruginosa (NIES-100).
Micropeptins C (1), D (2), E (3), and F (4) have been isolated from the freshwater cyanobacterium Microcystis aeruginosa (NIES-100). The structures were elucidated by analyses of MS, NMR spectra, and chemical degradation. Micropeptins C, D, E, and F inhibited chymotrypsin with IC(50)'s of 1.1, 1.2, 1.0, and 1.5 microg/mL, respectively.
Kisugi
Takaya
T
Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan.
Okino
Tatsufumi
T
D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D047630:Depsipeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005618:Fresh Water; D020128:Inhibitory Concentration 50; D046931:Microcystis / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
D047630:Depsipeptides; D002918:Chymotrypsin