title: [Thrombolysis of the middle cerebral artery].
abstract: Intravenous thrombolysis (IVT) is the evidence-based treatment of acute ischemic stroke in the first 3 h after symptom onset (IVT 3-4.5 h: off-label use with informed consent of the patient). However, intra-arterial thrombolysis (IAT) results in higher recanalization rates of the middle cerebral artery compared to IVT. Therefore it seems reasonable to apply IAT in addition or instead of IVT up to 6 h after symptom onset.
authors.affiliation: Institut für Diagnostische und Interventionelle Neuroradiologie, Inselspital Bern, Freiburgstr. 4, CH-3010, Bern, Schweiz. caspar.brekenfeld@insel.ch
authors.forename: C
authors.initials: C
authors.lastname: Brekenfeld
authors.forename: J
authors.initials: J
authors.lastname: Gralla
authors.forename: H-P
authors.initials: HP
authors.lastname: Mattle
authors.forename: M
authors.initials: M
authors.lastname: El-Koussy
authors.forename: G
authors.initials: G
authors.lastname: Schroth
mesh_terms: D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis* / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods* / Q000639:trends*
chemical_list: D005343:Fibrinolytic Agents