title: A randomized trial to increase physical activity in breast cancer survivors.
abstract: OBJECTIVE
  Interventions to increase physical activity among breast cancer survivors are needed to improve health and quality of life and possibly to reduce the risk of disease recurrence and early mortality. Therefore, we report the feasibility and preliminary outcomes of a pilot randomized trial designed to increase physical activity in sedentary breast cancer survivors receiving hormone therapy.
  
  
  METHODS
  Forty-one sedentary women on estrogen receptor modulators or aromatase inhibitors for stage I, II, or IIIA breast cancer were randomly assigned to receive a 12-wk multidisciplinary physical activity behavior change intervention or usual care.
  
  
  RESULTS
  Recruitment was 34%, intervention adherence was 99%, and complete follow-up data were obtained on 93%. Most participants (93%) were white with mean age of 53 +/- 9 yr. Differences favoring the intervention group were noted for accelerometer physical activity counts (mean difference = 72,103; 95% confidence interval (CI) = 25,383-119,000; effect size (d) = 1.02; P = 0.004), aerobic fitness (mean difference = 2.9; 95% CI = -0.1 to 5.8; d = 0.64; P = 0.058), back/leg muscle strength (mean difference = 12.3; 95% CI = 0.4-15.9; d = 0.81; P = 0.017), waist-to-hip ratio (mean difference = -0.05; 95% CI = -0.01 to -0.08; d = -0.77; P = 0.018), and social well-being (mean difference = 2.0; 95% CI = 0.3-3.8; d = 0.76; P = 0.03). However, the intervention group also reported a greater increase in joint stiffness (mean difference = 1.1; 95% CI = 0.1-2.2; d = 0.70; P = 0.04).
  
  
  CONCLUSIONS
  A behavior change intervention for breast cancer survivors based on the social cognitive theory is feasible and results in potentially meaningful improvements in physical activity and selected health outcomes. Confirmation in a larger study is warranted.
authors.affiliation: Department of Medicine, SIU School of Medicine, Springfield, IL 62794-9636, USA. lrogers@siumed.edu
authors.forename: Laura Q
authors.initials: LQ
authors.lastname: Rogers
authors.forename: Patricia
authors.initials: P
authors.lastname: Hopkins-Price
authors.forename: Sandy
authors.initials: S
authors.lastname: Vicari
authors.forename: Richard
authors.initials: R
authors.lastname: Pamenter
authors.forename: Kerry S
authors.initials: KS
authors.lastname: Courneya
authors.forename: Stephen
authors.initials: S
authors.lastname: Markwell
authors.forename: Steven
authors.initials: S
authors.lastname: Verhulst
authors.forename: Karen
authors.initials: K
authors.lastname: Hoelzer
authors.forename: Catherine
authors.initials: C
authors.lastname: Naritoku
authors.forename: Linda
authors.initials: L
authors.lastname: Jones
authors.forename: Gary
authors.initials: G
authors.lastname: Dunnington
authors.forename: Victor
authors.initials: V
authors.lastname: Lanzotti
authors.forename: James
authors.initials: J
authors.lastname: Wynstra
authors.forename: Lisa
authors.initials: L
authors.lastname: Shah
authors.forename: Billie
authors.initials: B
authors.lastname: Edson
authors.forename: Ashleigh
authors.initials: A
authors.lastname: Graff
authors.forename: Michelle
authors.initials: M
authors.lastname: Lowy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000886:Anthropometry; D001823:Body Composition; D001943:Breast Neoplasms / Q000534:rehabilitation*; D015444:Exercise; D005260:Female; D006293:Health Promotion; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D040242:Risk Reduction Behavior; D017741:Survivors; D055815:Young Adult