Effect of the chitin synthesis inhibitor triflumuron on the development, viability and reproduction of Aedes aegypti.
The control of Aedes aegypti is impaired due to the development of resistance to chemical insecticides. Insect Growth Regulators (IGR) exhibit distinct mechanisms of action and are considered potential vector control alternatives. Studies regarding the effects of sublethal IGR doses on the viability of resulting adults will contribute to eval-uating their impact in the field. We analyzed several aspects of Ae. aegypti adults surviving exposure to a partially lethal dose of triflumuron, a chitin synthesis inhibitor. A highly significant difference in the proportion of males and females was noted in the triflumuron-exposed group (65.0% males) compared to the controls (50.2% males). Triflumuron affected adult longevity, particularly for females; after 16 days, only 29.2% of males and 13.8% of females were alive, in contrast with 94% survival of the control mosquitoes. The locomotor activity was reduced and the blood-feeding ability of the treated females was also affected (90.4% and 48.4% of the control and triflumuron-exposed females, respectively, successfully ingested blood). Triflumuron-surviving females ingested roughly 30% less blood and laid 25% fewer eggs than the control females. The treated males and females exhibited a diminished ability to copulate, resulting in less viable eggs.
Belinato
Thiago Affonso
TA
Laboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz-Fiocruz,Av. Brasil 4365, 21045-900 Rio de Janeiro, RJ, Brasil.
Martins
Ademir Jesus
AJ
Lima
José Bento Pereira
JB
Lima-Camara
Tamara Nunes de
TN
Peixoto
Alexandre Afrânio
AA
Valle
Denise
D
D000330:Aedes / Q000187:drug effects*; D000818:Animals; D001549:Benzamides / Q000494:pharmacology*; D002686:Chitin / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D007306:Insecticides / Q000494:pharmacology*; D007928:Lethal Dose 50; D008136:Longevity / Q000187:drug effects; D008297:Male; D010063:Ovum / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects
D001549:Benzamides; D007306:Insecticides; D002686:Chitin; C023957:triflumuron