title: HIV: medical milestones and clinical challenges.
abstract: Since its discovery in the 1980s, HIV has infected every continent on the globe by crossing socioeconomic, racial, ethnic, and gender barriers, and it continues to contribute to human morbidity and mortality. Advances in medicine and technology have led to new combination medications for HIV-positive patients, early HIV testing methodologies, and potential for an HIV vaccine, and they have given researchers and clinicians a larger armamentarium with which to treat and prevent the disease. Even with these vast improvements in HIV prevention, detection, and treatment, scientists have been unsuccessful in developing its vaccine. Therefore, the search for a cure for HIV remains the marathon of the millennium.
authors.affiliation: Department of Restorative Dentistry, The University of Texas Health Science Center at San Antonio Dental School, Mail Code 7890, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. petersk@uthscsa.edu
authors.forename: Kelly P
authors.initials: KP
authors.lastname: Halligan
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Halligan
authors.forename: Arthur H
authors.initials: AH
authors.lastname: Jeske
authors.forename: Sheila H
authors.initials: SH
authors.lastname: Koh
mesh_terms: D015492:AIDS Serodiagnosis; D019380:Anti-HIV Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data; D023241:Antiretroviral Therapy, Highly Active; D017742:Dental Care for Chronically Ill; D004347:Drug Interactions; D005380:Financing, Government / Q000331:legislation & jurisprudence; D015658:HIV Infections / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D015497:HIV-1 / Q000502:physiology; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control; D014481:United States / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents