title: Blockade of ICAM-1: a novel way of vasculitis treatment.
abstract: Vasculitis is becoming more common worldwide, but there is no effective therapeutic method towards this series of disease till now. Intercellular adhesion molecule (ICAM)-1 is one of an important cell adhesion molecules (CAMs) family glycoprotein that plays pivotal role in inflammation process and participates in vasculitis. Blockade of ICAM-1 has been witnessed with its satisfactory effect on inflammatory disease treatment. Therefore, this method may be considered as a novel way towards treatment of vasculitis.
authors.affiliation: Department of Pharmacology, Nanjing Medical University, PR China.
authors.forename: Youhua
authors.initials: Y
authors.lastname: Xu
authors.forename: Shengnan
authors.initials: S
authors.lastname: Li
mesh_terms: D002448:Cell Adhesion; D002465:Cell Movement; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism*; D014657:Vasculitis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology
chemical_list: D018799:Intercellular Adhesion Molecule-1