title: Asian ethnicity and the prevalence of metabolic syndrome in the osteoarthritic total knee arthroplasty population.
abstract: Metabolic syndrome (MS) is a known risk factor for the development of osteoarthritis (OA). We asked whether the prevalence of MS varies across ethnicity among patients who undergo total knee arthroplasty for end-stage OA. In our population of 1460 patients undergoing primary knee arthroplasty, MS was defined as body mass index greater than 30 kg/m(2), diabetes, hypertension, and hypercholesterolemia. Among the 1334 white patients, 114 (8.5%) had MS as compared with 3 of 36 (8.3%) blacks and 18 of 90 (20%) Asians (P = .006) Adjusted analysis showed that those of Asian ethnicity had a 2.0 (95% confidence interval, 1.1-3.8; P = .03) times greater odds of MS as compared with those of other ethnicity. Metabolic syndrome is a risk factor for OA, and Asians demonstrate a greater prevalence of MS as compared with whites and blacks in this population.
authors.affiliation: Division of Orthopedic Surgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Gandhi
authors.forename: Fahad
authors.initials: F
authors.lastname: Razak
authors.forename: Peggy
authors.initials: P
authors.lastname: Tso
authors.forename: J Roderick
authors.initials: JR
authors.lastname: Davey
authors.forename: Nizar N
authors.initials: NN
authors.lastname: Mahomed
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D044466:Asian People / Q000208:ethnology*; D044383:Black People / Q000208:ethnology; D002170:Canada; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology* / Q000208:ethnology*; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000601:surgery*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D044465:White People / Q000208:ethnology