Hepatitis B virus genotypes: "clinical & therapeutic implications".
Hepatitis B virus is a crucial public health problem in Pakistan. It has been classified into eight genotypes (A-H) based on genome sequence divergence. Hepatitis B virus genotypes have distinct geographical distributions. Recently genotypes of hepatitis B have received a lot of attention due to its clinical as well as therapeutic importance. In this review, we will discuss the epidemiology, clinical outcome and response to antiviral therapy for different hepatitis B virus genotypes.
Khawaja
Rajab Ali
RA
Department of Family & Community Medicine, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Khawaja
Asad Ali
AA
D000998:Antiviral Agents / Q000627:therapeutic use*; D005814:Genes, Viral / Q000235:genetics*; D005838:Genotype; D006509:Hepatitis B / Q000188:drug therapy* / Q000821:virology; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D017720:Molecular Epidemiology; D015995:Prevalence; D012307:Risk Factors; D000077596:Thymalfasin; D013947:Thymosin / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000998:Antiviral Agents; D016898:Interferon-alpha; D013947:Thymosin; D000077596:Thymalfasin