[Cholesterol gallstone pathogenesis].
Theoretically formation of cholesterol gallstone includes four steps, each one necessary for the next: 1) Metabolic or genetic defect, 2) Formation of supersaturated bilis, 3) Nucleation and 4) Growing of cholesterol crystals. In this work we review biliary physiology, each one of the mentionated steps and gallbladder alterations that have been to date investigated during lithogenesis.
Méndez
N
N
Departamento de Gastroenterología, Instituto Nacional de la Nutrición "Salvador Zubirán", Vasco de Quiroga núm. 15, México 14000, DF México.
Uribe
M
M
Jessurun
J
J
Uscanga
L
L
D000818:Animals; D001646:Bile / Q000378:metabolism; D001647:Bile Acids and Salts / Q000378:metabolism; D002769:Cholelithiasis / Q000209:etiology* / Q000235:genetics / Q000378:metabolism; D002784:Cholesterol / Q000032:analysis / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000633:toxicity; D003460:Crystallization; D005704:Gallbladder / Q000378:metabolism; D042882:Gallstones / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D009077:Mucins / Q000378:metabolism; D012589:Sciuridae / Q000378:metabolism; D012995:Solubility
D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D009077:Mucins; D002784:Cholesterol