title: Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup.
abstract: Breathlessness is common in advanced disease and can have a devastating impact on patients and carers. Research on the management of breathlessness is challenging. There are relatively few studies, and many studies are limited by inadequate power or design. This paper represents a consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup. The aims of this paper are to facilitate the design of adequately powered multi-centre interventional studies in breathlessness, to suggest a standardised, rational approach to breathlessness research and to aid future 'between study' comparisons. Discussion of the physiology of breathlessness is included.
authors.affiliation: Poole Hospital NHS Foundation Trust, Longfleet Road, Poole. saskie.dorman@poole.nhs.uk
authors.forename: S
authors.initials: S
authors.lastname: Dorman
authors.forename: C
authors.initials: C
authors.lastname: Jolley
authors.forename: A
authors.initials: A
authors.lastname: Abernethy
authors.forename: D
authors.initials: D
authors.lastname: Currow
authors.forename: M
authors.initials: M
authors.lastname: Johnson
authors.forename: M
authors.initials: M
authors.lastname: Farquhar
authors.forename: G
authors.initials: G
authors.lastname: Griffiths
authors.forename: T
authors.initials: T
authors.lastname: Peel
authors.forename: S
authors.initials: S
authors.lastname: Moosavi
authors.forename: A
authors.initials: A
authors.lastname: Byrne
authors.forename: A
authors.initials: A
authors.lastname: Wilcock
authors.forename: L
authors.initials: L
authors.lastname: Alloway
authors.forename: C
authors.initials: C
authors.lastname: Bausewein
authors.forename: I
authors.initials: I
authors.lastname: Higginson
authors.forename: S
authors.initials: S
authors.lastname: Booth
mesh_terms: D001294:Attitude to Health; D002986:Clinical Trials as Topic; D016638:Critical Illness; D003625:Data Collection / Q000379:methods; D018450:Disease Progression; D004417:Dyspnea / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005069:Evaluation Studies as Topic; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods; D010166:Palliative Care; D018579:Patient Selection; D011788:Quality of Life; D012107:Research Design; D012119:Respiration; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D019452:Terminally Ill; D006113:United Kingdom