title: Bioactive components of tea: cancer, inflammation and behavior.
abstract: Tea is one of the most widely consumed beverages worldwide. Several studies have suggested that catechins and theaflavins found in tea may reduce the risk of various types of cancers. Major advances have been made to understand the molecular events leading to cancer prevention; however, the evidence is not conclusive. Evidence from pre-clinical and clinical studies also suggests that persistent inflammation can progress to cancer. Several possible mechanisms of action may explain the cancer preventive aspects of tea components specifically anti-inflammatory effects. In regards to brain health, green tea catechins have been recognized as multifunctional compounds for neuroprotection with beneficial effects on vascular function and mental performance. Theanine, a unique amino acid in tea, enhances cognition in humans and has neuroprotective effects. Human interventional studies with well characterized tea products are needed.
authors.affiliation: Department of Food Science and Human Nutrition, University of Illinois-Urbana-Champaign, 1201 W. Gregory Drive, Urbana, IL 61801, USA. edemejia@illinois.edu
authors.forename: Elvira Gonzalez
authors.initials: EG
authors.lastname: de Mejia
authors.forename: Marco Vinicio
authors.initials: MV
authors.lastname: Ramirez-Mares
authors.forename: Sirima
authors.initials: S
authors.lastname: Puangpraphant
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D001519:Behavior / Q000187:drug effects*; D001522:Behavior, Animal / Q000187:drug effects*; D005247:Feeding Behavior; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology; D013662:Tea / Q000737:chemistry*
chemical_list: D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D013662:Tea