title: Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger).
abstract: In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3) cells were incubated with these compounds and the release of beta-hexosaminidase was measured kinetically. The data obtained suggest that ginger rhizomes harbor potent compounds capable of inhibiting allergic reactions and may be useful for the treatment and prevention of allergic diseases.
authors.affiliation: Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China.
authors.forename: Bing-Hung
authors.initials: BH
authors.lastname: Chen
authors.forename: Pei-Yu
authors.initials: PY
authors.lastname: Wu
authors.forename: Kuan-Ming
authors.initials: KM
authors.lastname: Chen
authors.forename: Tzu-Fun
authors.initials: TF
authors.lastname: Fu
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Wang
authors.forename: Chung-Yi
authors.initials: CY
authors.lastname: Chen
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D020939:Zingiber officinale / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D051381:Rats; D027343:Rhizome / Q000737:chemistry; D013624:Taiwan
chemical_list: D018926:Anti-Allergic Agents; D010636:Phenols