title: Multidimensional en-face OCT imaging of the retina.
abstract: Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images of the fundus and B-scan OCT images. Benefits in combining T-scan OCT with confocal imaging to generate pairs of OCT and confocal images similar to those generated by scanning laser ophthalmoscopy (SLO) are discussed in comparison with the spectral OCT systems. The multichannel potential of the OCT/SLO system is demonstrated with the addition of a third hardware channel which acquires and generates indocyanine green (ICG) fluorescence images. The OCT, confocal SLO and ICG fluorescence images are simultaneously presented in a two or a three screen format. A fourth channel which displays a live mix of frames of the ICG sequence superimposed on the corresponding coronal OCT slices for immediate multidimensional comparison, is also included. OSA ISP software is employed to illustrate the synergy between the simultaneously provided perspectives. This synergy promotes interpretation of information by enhancing diagnostic comparisons and facilitates internal correction of movement artifacts within C-scan and B-scan OCT images using information provided by the SLO channel.
authors.affiliation: Advanced Retinal Imaging Center, New York Eye and Ear Infirmary, New York, New York, USA.
authors.forename: Richard B
authors.initials: RB
authors.lastname: Rosen
authors.forename: Mark
authors.initials: M
authors.lastname: Hathaway
authors.forename: John
authors.initials: J
authors.lastname: Rogers
authors.forename: Justin
authors.initials: J
authors.lastname: Pedro
authors.forename: Patricia
authors.initials: P
authors.lastname: Garcia
authors.forename: Philippe
authors.initials: P
authors.lastname: Laissue
authors.forename: George M
authors.initials: GM
authors.lastname: Dobre
authors.forename: Adrian G
authors.initials: AG
authors.lastname: Podoleanu
mesh_terms: D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000473:pathology; D003930:Diabetic Retinopathy / Q000175:diagnosis / Q000473:pathology; D004867:Equipment Design; D005456:Fluorescent Dyes; D005654:Fundus Oculi; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007208:Indocyanine Green; D007834:Lasers; D019721:Ophthalmoscopes; D009887:Ophthalmoscopy / Q000379:methods; D055620:Optical Phenomena; D012160:Retina / Q000033:anatomy & histology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data
chemical_list: D005456:Fluorescent Dyes; D007208:Indocyanine Green