title: Prevention of mandibular third molar extraction-associated periodontal defects: a comparative study.
abstract: BACKGROUND
  Extraction of deep-impacted mandibular third molars may lead to periodontal defects at the distal surface of the adjacent second molar. The purpose of this study was to compare the ability of three regenerative approaches to prevent third molar extraction-related periodontal defects.
  
  
  METHODS
  Forty-five patients with bilateral osseous or soft tissue-impacted lower third molars were selected to participate in the study. Inclusion criteria were the presence of a pocket that was located distally to the mandibular second molar with a probing depth (PD) >or=7 mm and with a probing clinical attachment level (CAL) >or=6 mm. Ninety third molar impactions were used and were randomly assigned to three equal treatment groups (30 each): bovine porous bone mineral (BPBM) alone, BPBM plus collagen membrane (CM), and an untreated control group. Clinical and radiographic measurements were recorded at 3, 6, 9, 12, 18, 24, 36, 48, 60, and 72 months after the surgery.
  
  
  RESULTS
  BPBM or BPBM + CM resulted in a significant reduction in PD and gain in CAL compared to the control group at all time points. BPBM + CM had the best outcome for the prevention of a second-molar periodontal defect.
  
  
  CONCLUSIONS
  The application of BPBM, with or without a collagen membrane, can be a viable and stable treatment to alleviate the periodontal defects that are often associated with impacted mandibular third molar extractions.
authors.affiliation: Department of Oral and Maxillofacial Sciences, University of Naples "Federico II," Naples, Italy. gilberto.sammartino@unina.it
authors.forename: Gilberto
authors.initials: G
authors.lastname: Sammartino
authors.forename: Mariano
authors.initials: M
authors.lastname: Tia
authors.forename: Tommaso
authors.initials: T
authors.lastname: Bucci
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use; D001857:Bone Matrix / Q000637:transplantation; D018786:Bone Substitutes / Q000627:therapeutic use; D003094:Collagen; D003774:Dental Plaque Index; D005260:Female; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000517:prevention & control; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008567:Membranes, Artificial; D008903:Minerals / Q000627:therapeutic use; D008964:Molar, Third / Q000601:surgery*; D017622:Periodontal Attachment Loss / Q000517:prevention & control; D010510:Periodontal Diseases / Q000517:prevention & control*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control*; D014081:Tooth Extraction / Q000009:adverse effects*; D014095:Tooth, Impacted / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: C106416:Bio-Gide; C077540:Bio-Oss; D001672:Biocompatible Materials; D018786:Bone Substitutes; D008567:Membranes, Artificial; D008903:Minerals; D003094:Collagen