Prognostic value of increased adiponectin plasma concentrations in patients with acute destabilized heart failure.
OBJECTIVE
To evaluate the prognostic value of adiponectin in patients with acute destabilized heart failure.


METHODS
Adiponectin was measured in 137 consecutive heart failure patients attending an emergency department. The endpoint was 1-year all-cause mortality.


RESULTS
In Cox proportional-hazards regression, an adiponectin plasma concentration>24.1 mg/L had a risk ratio of 2.46 (95% CI, 1.24-4.87), independently of classical risk factors and B-type natriuretic peptide.


CONCLUSIONS
Adiponectin predicts mortality in patients with acute destabilized heart failure.
Dieplinger
Benjamin
B
Department of Laboratory Medicine, Konventhospital Barmherzige Brueder, Seilerstaette 2-4, A-4020 Linz, Austria.
Gegenhuber
Alfons
A
Poelz
Werner
W
Haltmayer
Meinhard
M
Mueller
Thomas
T
D000208:Acute Disease; D052242:Adiponectin / Q000097:blood*; D015331:Cohort Studies; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D053208:Kaplan-Meier Estimate; D011379:Prognosis; D016016:Proportional Hazards Models
D052242:Adiponectin