[GIST: our experience].
Gastrointestinal stromal tumors (GIST) are generally found in the stomach or small intestine and less commonly in the colon and rectum. Complete surgical remove remains the best current therapy. In the treatment of advanced/metastatic GIST is available imatinib, a selective tyrosine kinase inhibitor. In our experience, 12 patients observed between 2000 and 2007 and affected by GIST underwent surgery, in one case associated to treatment with imatinib.
Rossi
M T
MT
Fasano
G
G
Morlino
A
A
Scutari
F
F
D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D003131:Combined Modality Therapy; D013505:Digestive System Surgical Procedures; D005500:Follow-Up Studies; D005743:Gastrectomy; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy / Q000453:epidemiology* / Q000556:secondary / Q000601:surgery; D006801:Humans; D000068877:Imatinib Mesylate; D007558:Italy / Q000453:epidemiology; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D009852:Omentum / Q000601:surgery; D010879:Piperazines / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D012189:Retrospective Studies
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate