Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis.
The Enterococcus faecalis class IIa bacteriocin MC4-1 encoded by the sex pheromone-responding, multiple-antibiotic resistance plasmid pAMS1 exhibits "siblicidal" (sibling-killing) activity under certain conditions. Stabs of plasmid-containing cells on solid medium containing lawns of bacteria of the same (plasmid-containing) strain give rise to zones of inhibition. If the plasmid-containing host also produces gelatinase, bacteriocin cannot be detected.
Sedgley
Christine M
CM
Department of Cariology, Restorative Sciences & Endodontics, School of Dentistry, The University of Michigan, 1011 N. University Ave., Ann Arbor, MI 48109-1078, USA. csedgley@umich.edu
Clewell
Don B
DB
Flannagan
Susan E
SE
D000900:Anti-Bacterial Agents / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000494:pharmacology*; D001430:Bacteriocins / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000235:genetics / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000235:genetics; D018093:Gelatinases / Q000378:metabolism; D005798:Genes, Bacterial; D050296:Microbial Viability; D010957:Plasmids
D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D018093:Gelatinases