title: [Hemostasis management in multiple trauma patients--value of near-patient diagnostic methods].
abstract: Massively transfused multiple trauma patients commonly develop a complex coagulopathy which needs immediate treatment. Near-patient diagnostic methods are available for the management of this coagulopathy and for the guidance of the therapeutic options with blood products and haemostatic drugs: conventional laboratory analysis methods adapted to the point-of-care (POC) situation (blood gas analysis, point of care PT, APTT and platelet count), and the complex whole blood methods used for near-patient coagulation monitoring (thromboelastometry and platelet function analysis). Based on the new Guidelines of the German Medical Association for the use of blood and plasma derivates, interventions with blood products and haemostatic drugs in multiple trauma patients are suggested. The diagnostic value of near-patient methods for coagulation monitoring is discussed.
authors.affiliation: Department of Anaesthesiology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Csilla
authors.initials: C
authors.lastname: Jámbor
authors.forename: Bernhard
authors.initials: B
authors.lastname: Heindl
authors.forename: Michael
authors.initials: M
authors.lastname: Spannagl
authors.forename: Caroline
authors.initials: C
authors.lastname: Rolfes
authors.forename: Gerhard Klaus
authors.initials: GK
authors.lastname: Dinges
authors.forename: Thomas
authors.initials: T
authors.lastname: Frietsch
mesh_terms: D001778:Blood Coagulation Disorders / Q000209:etiology / Q000628:therapy; D001779:Blood Coagulation Factors / Q000627:therapeutic use; D016913:Blood Component Transfusion / Q000592:standards*; D006400:Hematocrit; D006487:Hemostasis / Q000502:physiology*; D006489:Hemostatic Techniques / Q000592:standards*; D006801:Humans; D010949:Plasma; D010976:Platelet Count; D011994:Recombinant Proteins / Q000627:therapeutic use; D014947:Wounds and Injuries / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D001779:Blood Coagulation Factors; D011994:Recombinant Proteins