title: Conjunctival and episcleral Splendore-Hoeppli phenomenon.
abstract: The Splendore-Hoeppli phenomenon originally described in 1908 is a rare pathological state with an as yet unknown cause. Reported is the Splendore-Hoeppli phenomenon present in both eyes of a 36-year-old woman. The pathology then proceeded to resolve itself completely within 10 weeks. Of note was the fact that the patient actually developed these granulomata despite being on high doses of oral steroids with the lesions disappearing despite her steroids being withdrawn during the resolution phase. An indication is that the phenomenon is unlikely to be because of an autoimmune response.
authors.affiliation: Princess Alexandra Hospital, Brisbane, Queensland, Australia. nigelpinto@y7mail.com
authors.forename: Nigel
authors.initials: N
authors.lastname: Pinto
authors.forename: Lawrence
authors.initials: L
authors.lastname: Hirst
authors.forename: Michael
authors.initials: M
authors.lastname: Whitby
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications / Q000276:immunology; D003228:Conjunctiva / Q000276:immunology / Q000473:pathology*; D003229:Conjunctival Diseases / Q000276:immunology / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007249:Inflammation / Q000473:pathology; D012075:Remission, Spontaneous; D012590:Sclera / Q000276:immunology / Q000473:pathology*; D016176:T-Lymphocyte Subsets / Q000276:immunology
chemical_list: D007073:Immunoglobulin E