title: Screening of dipeptides having central functions for excitation and sedation.
abstract: The naturally-occurring dipeptide carnosine (beta-alanyl-L-histidine) and the tripeptide glutathione (L-gammaglutamyl-L-cysteinylglycine) are found extensively in animal tissues such as brain and skeletal muscle. Central functions for excitation and sedation of them and their derivatives were screened.
authors.affiliation: Laboratory of Advanced Animal and Marine Bioresources, Faculty of Agriculture, Kyushu University, Fukuoka 812-8581, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamane
authors.forename: D M
authors.initials: DM
authors.lastname: Denbow
authors.forename: M
authors.initials: M
authors.lastname: Furuse
mesh_terms: D000818:Animals; D002336:Carnosine / Q000031:analogs & derivatives / Q000494:pharmacology / Q000502:physiology; D000697:Central Nervous System Stimulants / Q000494:pharmacology*; D004151:Dipeptides / Q000494:pharmacology* / Q000502:physiology; D004353:Drug Evaluation, Preclinical; D005978:Glutathione / Q000031:analogs & derivatives / Q000494:pharmacology / Q000502:physiology; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008954:Models, Biological; D015394:Molecular Structure
chemical_list: D000697:Central Nervous System Stimulants; D004151:Dipeptides; D006993:Hypnotics and Sedatives; D002336:Carnosine; D005978:Glutathione