title: Analysis of the outcome in male and female patients using a unisex total knee replacement system.
abstract: Gender-specific total knee replacement has generated much interest recently. We reviewed 1970 Sigma knees implanted in 920 women and 592 men with a mean age of 69.7 years. At a mean follow-up of 7.3 years (minimum, five years), we found minimal differences in the outcome between genders. At the final follow-up, men had a higher overall Knee Society score and more osteolysis (3.8% vs 1.1%). However, there were no significant differences between men and women in terms of complications or improvements in knee function, pain score or range of movement. The estimated ten-year survivorship was 97% in women and 98% in men (p = 0.96). We concluded that there was little difference in outcome between the genders treated by a modern unisex design of total knee replacement in this large multicentre study.
authors.affiliation: St. Joseph Medical Center, Baltimore, Maryland, USA. ehenze1@jhmi.edu
authors.forename: D F
authors.initials: DF
authors.lastname: Dalury
authors.forename: J B
authors.initials: JB
authors.lastname: Mason
authors.forename: J A
authors.initials: JA
authors.lastname: Murphy
authors.forename: M J
authors.initials: MJ
authors.lastname: Adams
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects / Q000379:methods*; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery; D010147:Pain Measurement; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D020127:Recovery of Function; D012737:Sex Factors; D016896:Treatment Outcome