Numerical characterization of DNA sequences based on digital signal method.
Based on digital signal method, we propose a new representation of DNA primary sequence. The representation can completely avoid loss of information in the transfer of data from a DNA sequence to its mathematical representation. Afterwards, we suggest one such approach to reach quantification of similarities based on digital signal similarity theory. The examination of similarities/dissimilarities among the coding sequences of the first exon of beta-globin gene of 11 species shows the utility of the scheme.
Qi
Zhao-Hui
ZH
School of Computer and Information Engineering, Shijiazhuang Railway Institute, Shijiazhuang, Hebei 050043, People's Republic of China. zhqi_yh2004@yahoo.com.cn
Qi
Xiao-Qin
XQ
D000465:Algorithms; D000818:Animals; D001483:Base Sequence; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D004247:DNA / Q000235:genetics; D005091:Exons; D006801:Humans; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D015203:Reproducibility of Results; D017422:Sequence Analysis, DNA / Q000379:methods*; D013045:Species Specificity; D055544:beta-Globins / Q000737:chemistry / Q000235:genetics*
D055544:beta-Globins; D004247:DNA