title: A nonsimultaneous, extended, altruistic-donor chain.
abstract: We report a chain of 10 kidney transplantations, initiated in July 2007 by a single altruistic donor (i.e., a donor without a designated recipient) and coordinated over a period of 8 months by two large paired-donation registries. These transplantations involved six transplantation centers in five states. In the case of five of the transplantations, the donors and their coregistered recipients underwent surgery simultaneously. In the other five cases, "bridge donors" continued the chain as many as 5 months after the coregistered recipients in their own pairs had received transplants. This report of a chain of paired kidney donations, in which the transplantations were not necessarily performed simultaneously, illustrates the potential of this strategy.
authors.affiliation: Department of Urology, University of Toledo Medical Center, Toledo, OH 43614, USA. michael.rees2@utoledo.edu
authors.forename: Michael A
authors.initials: MA
authors.lastname: Rees
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Kopke
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Pelletier
authors.forename: Dorry L
authors.initials: DL
authors.lastname: Segev
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Rutter
authors.forename: Alfredo J
authors.initials: AJ
authors.lastname: Fabrega
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Rogers
authors.forename: Oleh G
authors.initials: OG
authors.lastname: Pankewycz
authors.forename: Janet
authors.initials: J
authors.lastname: Hiller
authors.forename: Alvin E
authors.initials: AE
authors.lastname: Roth
authors.forename: Tuomas
authors.initials: T
authors.lastname: Sandholm
authors.forename: M Utku
authors.initials: MU
authors.lastname: Unver
authors.forename: Robert A
authors.initials: RA
authors.lastname: Montgomery
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology; D000328:Adult; D000533:Altruism; D005260:Female; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009927:Tissue and Organ Procurement / Q000379:methods* / Q000458:organization & administration
chemical_list: D000017:ABO Blood-Group System