Increasing invasive disease due to penicillin resistant S. pneumoniae in India.
S. pneumoniae continues to be a major cause of invasive disease worldwide with considerable mortality and morbidity. Here we report the emergence of penicillin intermediate resistance to S. pneumoniae in India, which may predispose for an increased incidence of invasive pneumococcal disease in both children and adults with multi-drug resistance profile resulting in clinical failure.
Balaji
Veeraraghavan
V
Department of Clinical Microbiology, Christian Medical College, Vellore, India. vbalaji@cmcvellore.ac.in
Thomas
Kurien
K
Joshi
Hari Har
HH
Beall
Bernard
B
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007194:India; D008297:Male; D010068:Oxacillin / Q000494:pharmacology; D010403:Penicillin Resistance; D013290:Streptococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000187:drug effects / Q000302:isolation & purification*; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D002443:Ceftriaxone; D010068:Oxacillin