title: Attribution of Campylobacter infections in northeast Scotland to specific sources by use of multilocus sequence typing.
abstract: We show that a higher incidence of campylobacteriosis is found in young children (age, <5 years) living in rural, compared with urban, areas. Association of this difference with particular animal sources was evaluated using multilocus sequence typing. This evaluation was achieved by comparing Campylobacter isolates originating from these children, retail poultry, and a range of animal sources by use of source attribution and phylogenetic analysis methods. The results indicate that chicken is a major source of infection in young urban children, although not in their rural counterparts, for which ruminant and other avian sources are more important.
authors.affiliation: School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom. n.strachan@abdn.ac.uk
authors.forename: Norval J C
authors.initials: NJ
authors.lastname: Strachan
authors.forename: Fraser J
authors.initials: FJ
authors.lastname: Gormley
authors.forename: Ovidiu
authors.initials: O
authors.lastname: Rotariu
authors.forename: Iain D
authors.initials: ID
authors.lastname: Ogden
authors.forename: Gordon
authors.initials: G
authors.lastname: Miller
authors.forename: Geoff M
authors.initials: GM
authors.lastname: Dunn
authors.forename: Samuel K
authors.initials: SK
authors.lastname: Sheppard
authors.forename: John F
authors.initials: JF
authors.lastname: Dallas
authors.forename: Thomas M S
authors.initials: TM
authors.lastname: Reid
authors.forename: Helen
authors.initials: H
authors.lastname: Howie
authors.forename: Martin C J
authors.initials: MC
authors.lastname: Maiden
authors.forename: Ken J
authors.initials: KJ
authors.lastname: Forbes
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D000829:Animals, Domestic; D001717:Birds; D002167:Campylobacter / Q000145:classification* / Q000235:genetics; D002169:Campylobacter Infections / Q000453:epidemiology* / Q000382:microbiology*; D002417:Cattle; D002645:Chickens; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D012424:Rural Population; D012606:Scotland / Q000453:epidemiology; D017422:Sequence Analysis, DNA; D012756:Sheep; D013552:Swine; D014505:Urban Population; D055815:Young Adult