[Hypervalent halogans and their reactions in organic synthesis].
This review provides an overview of the chemistry of hypervalent organohalogans, organoiodanes and organobromanes, developed recently in Tokushima. Vinylic S(N)2 reactions, cyclopentene syntheses via 1,5 C-H insertion of alkylidene carbenes, reductive Claisen rearrangements, oxidations with peroxy-lambda(3)-iodanes, iodobenzene-catalyzed oxidations, oxidative cleavage of double bonds, oxidative coupling of alcohols with alkynes, Michael additions, and transylidations are involved. These reactions mostly rely on the hyperleaving group ability of aryl-lambda(3)-iodanyl, -bromanyl, and -chloranyl groups.
Ochiai
Masahito
M
Department of Pharmaceutical Organic Chemistry, Institute of Health Biosciences, Graduate School of the University of Tokushima, Tokushima, Japan. mochiai@ph.tokushima-u.ac.jp
D001966:Bromine; D002384:Catalysis; D055808:Drug Discovery; D006219:Halogens; D007455:Iodine; D055601:Organic Chemistry Phenomena; D010084:Oxidation-Reduction
D006219:Halogens; D007455:Iodine; D001966:Bromine