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Stem cells are miraculous things. These primitive undifferentiated cells are normally present in the bone marrow and develop into red cells, white cells and platelets. The bone marrow can be stimulated to produce more stem cells than needed through the use of stimulating factors, for example, Granulocyte Colony Stimulating Factor or GCSF. These extra stem cells spill out from the bone marrow into the peripheral circulation. Using a blood cell separator they can be collected from the circulating blood and given to a recipient.
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D046148:Donor Selection / Q000458:organization & administration*; D006297:Health Services Accessibility; D006801:Humans; D036102:Peripheral Blood Stem Cell Transplantation / Q000379:methods; D012042:Registries; D014195:Travel; D006113:United Kingdom