[Management of pediatric testicular tumors : diagnosis, therapy, and follow-up].
Based on findings from the Prepubertal Testis Tumor Registry by the Urologic Section of the American Academy of Pediatrics and collaborative data in the literature, a modern algorithm for the surgical management of prepubertal testis tumors is presented. Following testicular surgery, patients with universally benign tumors, such as teratoma, may be released from oncological follow-up. Children with stage I yolk sac tumors should be monitored closely with periodic AFP tumor marker evaluation and imaging according to the primary dissemination (e.g., ultrasound, chest x-ray, and computed tomography). Patients with recurrent or metastatic yolk sac tumors should be treated with platinum-based chemotherapy and appropriate follow-up. Retroperitoneal lymph node dissection is not recommended except for patients with residual retroperitoneal masses following chemotherapy. Aggressive treatment is warranted for metastatic Sertoli cell and metastatic undifferentiated stromal tumors.
Steffens
J
J
Klinik für Urologie und Kinderurologie, St. Antonius-Hospital, Dechant-Deckers-Strasse 8, 52249, Eschweiler, Deutschland. joachim.steffens@sah-eschweiler.de
Treiyer
A
A
Calaminus
G
G
D002648:Child; D006801:Humans; D008297:Male; D008495:Medical Oncology / Q000639:trends*; D010372:Pediatrics / Q000639:trends*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000628:therapy*