The Cu(II) complex of Abeta40 peptide in ammonium acetate solutions. Evidence for ternary species formation.
Fluorimetric Cu(ii) titrations of Alzheimer's disease (AD) Abeta40 peptide at various ammonium acetate concentrations demonstrated that ternary Cu(Abeta40)L complexes are formed with buffer components L, thereby providing a novel perspective on Cu(ii)-Abeta interactions.
Rózga
Małgorzata
M
Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Protas
Anna M
AM
Jabłonowska
Agnieszka
A
Dadlez
Michał
M
Bal
Wojciech
W
D000085:Acetates / Q000737:chemistry*; D016229:Amyloid beta-Peptides / Q000737:chemistry* / Q000378:metabolism; D003300:Copper / Q000737:chemistry* / Q000378:metabolism; D046911:Macromolecular Substances; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism; D011485:Protein Binding; D012996:Solutions / Q000737:chemistry; D013050:Spectrometry, Fluorescence
D000085:Acetates; D016229:Amyloid beta-Peptides; D046911:Macromolecular Substances; D010446:Peptide Fragments; D012996:Solutions; C078592:amyloid beta-protein (1-40); D003300:Copper; C018824:ammonium acetate