Handling uncertainty of the economic evaluation result: sensitivity analysis.
An economic evaluation of health technology and interventions often comes with uncertainty in the parameters that were used in the model. To determine sensitivity of the result obtained from a reference case analysis, researchers can employ deterministic and probabilistic approaches. This methodological guideline summarizes the principles underlying the sensitivity analysis and recommends that the probabilistic sensitivity analysis is the best method to handle the parameter uncertainty.
Limwattananon
Supon
S
Faculty of Pharmaceutical Sciences, Khon Kaen University, Amphoe Muang, Khon Kaen 40002, Thailand. supon@kku.ac.th
D003362:Cost-Benefit Analysis; D006801:Humans; D009010:Monte Carlo Method; D017410:Practice Guidelines as Topic; D011336:Probability; D012680:Sensitivity and Specificity; D013673:Technology Assessment, Biomedical / Q000191:economics*; D013785:Thailand; D035501:Uncertainty