title: Direct amination of azoles via catalytic C-H, N-H coupling.
abstract: C-H, N-H Coupling of azoles takes place with several amines in the presence of a copper catalyst to undergo amination at the 2-position. The reaction of benzothiazole with N-methylaniline in the presence of sodium acetate and 20 mol % Cu(OAc)(2) in xylene under an oxygen atmosphere afforded the aminated product in 81% yield.
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan.
authors.forename: Daiki
authors.initials: D
authors.lastname: Monguchi
authors.forename: Taiki
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Atsunori
authors.initials: A
authors.lastname: Mori