title: Shift work, chronodisruption and cancer?--The IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008.
abstract: In October of 2007, an IARC panel of 24 scientists systematically evaluated epidemiologic, experimental, and mechanistic data and concluded that shift work that involves circadian or chronodisruption is probably carcinogenic in humans. In view of the possible scope of the problem--shift work is widespread and unavoidable on one hand and breast cancer and prostate cancer, which may be causally associated with chronodisruption, are epidemic worldwide on the other--German representatives of science and occupational medicine discussed the experimental and epidemiologic background and possible implications of the challenge identified by the International Agency for Research on Cancer (IARC) at a colloquium in Cologne in September 2008. This overview summarizes the key ideas presented at the Cologne Colloquium and offers 10 theses concerning the need for targeted studies and the necessity to develop possible means of prevention.
authors.affiliation: Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Str. 62, 50937 Köln, Germany. tim.erren@uni-koeln.de
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Erren
authors.forename: Peter
authors.initials: P
authors.lastname: Morfeld
authors.forename: Joachim
authors.initials: J
authors.lastname: Stork
authors.forename: Peter
authors.initials: P
authors.lastname: Knauth
authors.forename: Matthias J A
authors.initials: MJ
authors.lastname: von Mülmann
authors.forename: Rolf
authors.initials: R
authors.lastname: Breitstadt
authors.forename: Uta
authors.initials: U
authors.lastname: Müller
authors.forename: Michael
authors.initials: M
authors.lastname: Emmerich
authors.forename: Claus
authors.initials: C
authors.lastname: Piekarski
mesh_terms: D001943:Breast Neoplasms / Q000209:etiology*; D021081:Chronobiology Disorders / Q000517:prevention & control*; D003226:Congresses as Topic; D005260:Female; D006801:Humans; D008297:Male; D009787:Occupational Medicine; D011471:Prostatic Neoplasms / Q000209:etiology*; D012106:Research; D014940:Work Schedule Tolerance / Q000502:physiology*