title: Pancreatic cancer and pancreaticoduodenectomy in elderly patient: morbidity and mortality are increased. Is it the real life?
abstract: OBJECTIVE
  The aim of this study was to compare post-operative outcomes of two groups of patients aged more or less than 70 years old
  
  
  METHODS
  From January 1990 to January 2006, 150 patients underwent pancreaticoduodenectomy (PD) for pancreatic adenocarcinomas (PA) were reviewed at the Department of Digestive Surgery of University Hospital. Twenty five patients Group A> or =70 and Group B<70 years old, were well matched for gender, diagnosis, body mass index, American Society of Anesthesiologists (ASA) score, and texture of pancreatic parenchyma.
  
  
  RESULTS
  There was no intraoperative death. Mean operative hospital and intensive care unit stays were in Group A, B: 21+/-9; 4.5+/-8 vs. 19+/-7; 3+/-3 NS respectively. There were four deaths in A and no death in B at three months of hospital discharge. More patients had complications in Group A (56% vs 36% NS). Medical complications seem to be more frequent in Group A (40%vs 12% NS). The median survivals were 20 and 27 months for A and B, respectively.
  
  
  CONCLUSIONS
  We observed an increased rate of morbidity and mortality in patients aged more than 70 years.
authors.affiliation: Pôle d'oncologie et spécialités Médico-chirurgicales, Service de chirurgie digestive et oncologique, Hôpital Timone, Marseille, France. mehdi.ouaissi@mail.ap-hm.fr
authors.forename: Mehdi
authors.initials: M
authors.lastname: Ouaïssi
authors.forename: Igor
authors.initials: I
authors.lastname: Sielezneff
authors.forename: Nicolas
authors.initials: N
authors.lastname: Pirrò
authors.forename: Abelrahmane
authors.initials: A
authors.lastname: Merad
authors.forename: Anderson
authors.initials: A
authors.lastname: Loundou
authors.forename: Jean Baptiste
authors.initials: JB
authors.lastname: Chaix
authors.forename: Laetitia
authors.initials: L
authors.lastname: Dahan
authors.forename: Pauline
authors.initials: P
authors.lastname: Ries
authors.forename: Jean François
authors.initials: JF
authors.lastname: Seitz
authors.forename: Marie José
authors.initials: MJ
authors.lastname: Payan
authors.forename: Bernard
authors.initials: B
authors.lastname: Consentino
authors.forename: Bernard
authors.initials: B
authors.lastname: Sastre
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D009017:Morbidity; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome