title: A practical, two-step synthesis of 2-substituted 1,3-butadienes.
abstract: A two-step procedure for preparing 2-alkyl-1,3-butadienes is described. Cuprate addition to commercially available 1,4-dibromo-2-butene yields 3-alkyl-4-bromo-1-butene, a product of S(N)2' substitution. Dehydrohalogenation gives 2-alkyl-1,3-butadienes.
authors.affiliation: Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, USA.
authors.forename: Sushmita
authors.initials: S
authors.lastname: Sen
authors.forename: Swapnil
authors.initials: S
authors.lastname: Singh
authors.forename: Scott McN
authors.initials: SM
authors.lastname: Sieburth
mesh_terms: D002070:Butadienes / Q000138:chemical synthesis* / Q000737:chemistry; D054879:Halogenation; D015394:Molecular Structure
chemical_list: D002070:Butadienes