title: Persistent eyelid swelling in a patient with rosacea.
abstract: Persistent facial swelling may occur as a rare complication of rosacea. This finding has been referred to as lymphedematous rosacea, Morbihan's disease or persistent solid facial edema. A literature review for cases of lymphedematous rosacea revealed that the chronic inflammatory process that accompanies the disease contributes to an increase in the permeability of blood vessels. With time, the lymphatic drainage system becomes permanently impaired, leading to fluid accumulation in the affected skin. Herein, we report the case of a 58-year-old female with history of rosacea who developed bilateral periorbital swelling with associated erythema of the conjunctiva (ocular rosacea) over a 4 month period that only responded to oral corticosteroids. Biopsy revealed changes of lymphedematous rosacea.
authors.affiliation: Department of Dermatology, UPR School of Medicine. amorales@rcm.upr.edu
authors.forename: Adisbeth
authors.initials: A
authors.lastname: Morales-Burgos
authors.forename: Gilberto
authors.initials: G
authors.lastname: Alvarez Del Manzano
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Sánchez
authors.forename: Carmen L
authors.initials: CL
authors.lastname: Cruz
mesh_terms: D004487:Edema / Q000209:etiology*; D005141:Eyelid Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012393:Rosacea / Q000150:complications*