Substance use disorders in women with anorexia nervosa.
OBJECTIVE
We examined prevalence of substance use disorders (SUD) in women with: (1) anorexia nervosa (AN) restricting type (RAN); (2) AN with purging only (PAN); (3) AN with binge eating only (BAN); and (4) lifetime AN and bulimia nervosa (ANBN). Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating.


METHODS
Participants (N = 731) were drawn from the International Price Foundation Genetic Studies.


RESULTS
The prevalence of SUD differed across AN subtypes, with more in the ANBN group reporting SUD than those in the RAN and PAN groups. Individuals who purged were more likely to report substance use than those who did not purge. Prevalence of SUD differed across lifetime binge eating status.


CONCLUSIONS
SUD are common in AN and are associated with bulimic symptomatology. Results underscore the heterogeneity in AN, highlighting the importance of screening for SUD across AN subtypes.
Root
Tammy L
TL
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Pinheiro
Andréa Poyastro
AP
Thornton
Laura
L
Strober
Michael
M
Fernandez-Aranda
Fernando
F
Brandt
Harry
H
Crawford
Steve
S
Fichter
Manfred M
MM
Halmi
Katherine A
KA
Johnson
Craig
C
Kaplan
Allan S
AS
Klump
Kelly L
KL
La Via
Maria
M
Mitchell
James
J
Woodside
D Blake
DB
Rotondo
Alessandro
A
Berrettini
Wade H
WH
Kaye
Walter H
WH
Bulik
Cynthia M
CM
D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000453:epidemiology*; D015992:Body Mass Index; D002032:Bulimia / Q000175:diagnosis / Q000453:epidemiology*; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D010552:Personality Assessment; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology*; D011795:Surveys and Questionnaires