title: Decoding the hemogenic endothelium in mammals.
abstract: A collection of recent Nature papers examines the relationship between endothelial precursors and hematopoietic cells. Two of these studies (Eilken et al., 2009; Lancrin et al., 2009) use time-lapse imaging with live markers and genetic analysis of differentiating ESCs to reveal that even non-aortic-derived endothelial cells are hemogenic.
authors.affiliation: UPMC, CNRS UMR7622, Laboratoire de Biologie du Développement, Bat C, 6(ème) étage, Case 24, Paris 75252, Cedex 05, France. francoise.dieterlen@club-internet.fr
authors.forename: Françoise
authors.initials: F
authors.lastname: Dieterlen-Lièvre
authors.forename: Thierry
authors.initials: T
authors.lastname: Jaffredo
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology*; D004730:Endothelium, Vascular / Q000502:physiology*; D055018:Hemangioblasts / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D051379:Mice