title: [Gastrointestinal oncology - therapy update 2008 / 2009].
abstract: As a consequence of recent studies the treatment of gastrointestinal cancers has become challenging and is undergoing constant changes on the basis of the results of new trials. The steering committee of the working group on gastrointestinal cancers of the Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten has decided to summarise and present recent updates of the current treatment guidelines and recommendations for the most relevant gastrointestinal malignancies. In this review we have included recent findings from large trials on esophageal, gastric, pancreatic, cholangiocellular and liver cancers, as well as colorectal cancers, neuroendocrine tumours and lymphomas. This includes an update on the combination with novel targeted agents and the introduction of potential predictive biomarkers in the selection of the appropriate treatment strategy.
authors.affiliation: II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, 81675 München. ebertm@gmx.de
authors.forename: M P
authors.initials: MP
authors.lastname: Ebert
authors.forename: C
authors.initials: C
authors.lastname: Auernhammer
authors.forename: K
authors.initials: K
authors.lastname: Caca
authors.forename: F
authors.initials: F
authors.lastname: Eckel
authors.forename: W
authors.initials: W
authors.lastname: Fischbach
authors.forename: M
authors.initials: M
authors.lastname: Geissler
authors.forename: B
authors.initials: B
authors.lastname: Göke
authors.forename: T
authors.initials: T
authors.lastname: Greten
authors.forename: S
authors.initials: S
authors.lastname: Kubicka
authors.forename: M P
authors.initials: MP
authors.lastname: Lutz
authors.forename: M
authors.initials: M
authors.lastname: Möhler
authors.forename: O
authors.initials: O
authors.lastname: Opitz
authors.forename: M
authors.initials: M
authors.lastname: Pavel
authors.forename: R
authors.initials: R
authors.lastname: Porschen
authors.forename: A
authors.initials: A
authors.lastname: Reinacher-Schick
authors.forename: W
authors.initials: W
authors.lastname: Schmiegel
authors.forename: T
authors.initials: T
authors.lastname: Seufferlein
authors.forename: B
authors.initials: B
authors.lastname: Wiedenmann
authors.forename: R M
authors.initials: RM
authors.lastname: Schmid
mesh_terms: D003131:Combined Modality Therapy; D005770:Gastrointestinal Neoplasms / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic