title: FactorY, a bioinformatic resource for genome-wide promoter analysis.
abstract: The interpretation of the complex molecular descriptions generated by high-throughput gene expression technologies is still challenging. The development of new tools to identify common regulatory mechanisms involved in the control of the expression of a set of co-expressed genes, might enhance our capacity to extract functional information from genomic data sets. Here we present FactorY, a website that allows identification of enriched transcription factor binding sites (TFBSs) in the proximal promoter of a cluster of genes, as well as functional interpretation, and intuitive visualization of the results.
authors.affiliation: Unit of Proteomics, Genomics and Bioinformatics, CIMA, Pamplona 31008, Spain. eguruce@unav.es
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Guruceaga
authors.forename: Victor
authors.initials: V
authors.lastname: Segura
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Corrales
authors.forename: Angel
authors.initials: A
authors.lastname: Rubio
mesh_terms: D001665:Binding Sites; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D005189:False Positive Reactions; D005786:Gene Expression Regulation; D023281:Genomics; D006801:Humans; D005810:Multigene Family; D020411:Oligonucleotide Array Sequence Analysis; D011381:Programming Languages; D011401:Promoter Regions, Genetic; D012984:Software; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D014157:Transcription Factors