title: Benzyne click chemistry with in situ generated aromatic azides.
abstract: An efficient synthesis of substituted benzotriazoles using an azide-alkyne 1,3-dipolar cycloaddition "click reaction" is described. Key to the procedure is the in situ generation of the reactive aromatic azide and benzyne reaction partners.
authors.affiliation: School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
authors.forename: Fengzhi
authors.initials: F
authors.lastname: Zhang
authors.forename: John E
authors.initials: JE
authors.lastname: Moses
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000138:chemical synthesis / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D001555:Benzene Derivatives; D014230:Triazoles; C524146:benzyne; C012771:benzotriazole