title: A rare case of malignant triton tumor with pluridirectional differentiation.
abstract: An enlarging soft tissue mass was resected from the leg of a young man with neurofibromatosis type 1. Rhabdomyosarcomatous elements admixed with islands of osteoid and chondroid matrix was seen on microscopy. Based on immunohistochemistry, a malignant triton tumor, an uncommon subtype of peripheral nerve sheath tumor with rhabdomyosarcomatous elements, was diagnosed. The important feature of this neoplasm was that it showed pluridirectional differentiation to osteosarcoma and chondrosarcoma. This pathologic finding is rare and seen in only a few cases of all malignant triton tumors.
authors.affiliation: 2nd Propaedeutic Department of Surgery, Medical Faculty, Aristotle University of Thessaloniki, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Ballas
authors.forename: Theodoros M
authors.initials: TM
authors.lastname: Kontoulis
authors.forename: Athanasios
authors.initials: A
authors.lastname: Papavasiliou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Pissas
authors.forename: Theodoros
authors.initials: T
authors.lastname: Pavlidis
authors.forename: Evangelia
authors.initials: E
authors.lastname: Katsiki
authors.forename: Ioannis
authors.initials: I
authors.lastname: Venizelos
authors.forename: Athanasios
authors.initials: A
authors.lastname: Sakadamis
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002813:Chondrosarcoma / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D012516:Osteosarcoma / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor