title: [Transjugular intrahepatic portosystemic shunt for refractory ascites: results in 50 patients].
abstract: In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.
authors.affiliation: Department of Gastroenterology, Nippon Medical School, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kanazawa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Narahara
authors.forename: Takeshi
authors.initials: T
authors.lastname: Fukuda
authors.forename: Chisa
authors.initials: C
authors.lastname: Kondo
authors.forename: Hirotomo
authors.initials: H
authors.lastname: Harimoto
authors.forename: Yoko
authors.initials: Y
authors.lastname: Matsushita
authors.forename: Hideko
authors.initials: H
authors.lastname: Kidokoro
authors.forename: Tamaki
authors.initials: T
authors.lastname: Katakura
authors.forename: Masanori
authors.initials: M
authors.lastname: Atsukawa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Taki
authors.forename: Yu
authors.initials: Y
authors.lastname: Kimura
authors.forename: Yuji
authors.initials: Y
authors.lastname: Osada
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Nakatsuka
authors.forename: Choitsu
authors.initials: C
authors.lastname: Sakamoto
mesh_terms: D001201:Ascites / Q000401:mortality / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011446:Prospective Studies; D011788:Quality of Life; D015996:Survival Rate; D016896:Treatment Outcome