title: Measurement of clinical effects.
abstract: The measurement and valuation of clinical effects is a significant component of economic evaluation. Decision makers are commonly interested in how a particular health intervention works in everyday practice; therefore, the resulting outcome under this circumstance is called the effectiveness. Clinical effects usually measure final intended effects of a proposed health technology in terms of the ultimate change in health state brought about by the technology. The systematic review and meta-analysis of high quality RCTs is the most favorable method to synthesize evidence because they are disciplined and transparent methods. The present chapter focuses on how to make a valid measure of clinical effects for use in cost-effectiveness analysis and how clinical effect is to be appropriately defined and measured.
authors.affiliation: Health Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi, Thailand. yot@ihpp.thaigov.net
authors.forename: Yot
authors.initials: Y
authors.lastname: Teerawattananon
authors.forename: Montarat
authors.initials: M
authors.lastname: Thavorncharoensap
authors.forename: Adun
authors.initials: A
authors.lastname: Mohara
mesh_terms: D003362:Cost-Benefit Analysis; D003657:Decision Making; D006801:Humans; D017059:Models, Econometric; D017063:Outcome Assessment, Health Care / Q000191:economics* / Q000379:methods / Q000592:standards; D017410:Practice Guidelines as Topic; D013673:Technology Assessment, Biomedical / Q000191:economics*; D013785:Thailand