title: Feasibility study of 3-T MR imaging of the skin.
abstract: The purpose of this study was to assess the quality of 3-T magnetic resonance (MR) imaging of the skin, to describe skin anatomy at 3 T and to discuss future prospects of skin MRI. A 7-cm single-element surface receiver coil was developed for our 3-T MRI system. Thin sections were obtained with a three-dimensional FIESTA acquisition sequence and a spin-echo T1-weighted sequence (SET1). Prospective analysis was performed twice by two radiologists independently. Thirty-six healthy volunteers were included and underwent MRI on the face and the calf. Image quality was assessed regarding visibility of skin layers and quantification of artefacts. High field strength MR enables imaging of the skin with a high spatial in-plane resolution (87-180 microm), the total examination lasting 15-20 min. Image quality was excellent for the calf (mean SET1 quality = 96%) with a high intra- and interobserver correlation (SET1 kappa coefficient concerning visibility of epidermis, dermis and hypodermis > or = 0.84). Motion artefacts resulted in a small loss of quality and reproducibility for the face. In conclusion, 3-T MR allows high spatial resolution imaging of the skin and can potentially provide an accurate noninvasive means of analysing the skin.
authors.affiliation: Service de Radiologie A, CHU Jean Minjoz, Boulevard Flemming, 25030, Besançon Cedex, France. radio.aubry@free.fr
authors.forename: Sébastien
authors.initials: S
authors.lastname: Aubry
authors.forename: Céline
authors.initials: C
authors.lastname: Casile
authors.forename: Philippe
authors.initials: P
authors.lastname: Humbert
authors.forename: Jérome
authors.initials: J
authors.lastname: Jehl
authors.forename: Chrystelle
authors.initials: C
authors.lastname: Vidal
authors.forename: Bruno
authors.initials: B
authors.lastname: Kastler
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000033:anatomy & histology*