Activation of dendritic cells by polymorphonuclear neutrophils.
The obsolete view describing neutrophils as innate immune cells that respond rapidly to microbial invasion and then rapidly die by apoptosis is now challenged by several data. In both human and mice, there are now evidences that neutrophils play a role in dendritic cell activation, a critical step for the outcome of the specific T cell response.
Boudaly
Sarah
S
Unite Mixte de Recherche 7151 Centre National de la Recherche Scientifique, Universite Denis Diderot Paris 7, Institut Universitaire d'Hematologie, Hopital Saint-Louis, Paris, France. sarah.boudaly@univ-paris-diderot.fr
D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation; D009504:Neutrophils / Q000276:immunology*