title: [Observe the curative effect of n-Butyl cyanoacrylate injection in treating laryngopharynx hemangioma].
abstract: OBJECTIVE
  To evaluate the clinical effectiveness of injection n-Butyl cyanoacrylate (NBCA) in treating laryngopharynx hemangioma.
  
  
  METHODS
  Thirty cases of laryngopharynx hemangioma who received NBCA injection were obtained from our department 1998-2007. Twenty-five cases had tracheotomy under General anesthesia, and NBCA was injected into hemangioma by direct laryngoscopy. NBCA was mixed with iodide, and the concentration was 25.00% to 33.33%, NBCA dosage was 0.5 ml to 2.0 ml. There were 5 cases whose hemangioma confined to oropharynx didn't have tracheotomy, and they were injected straightly with the speculum oris. We observed the shedding of hemangioma in different time.
  
  
  RESULTS
  Hemangioma with diameter less than 1 cm, shedded in about 1 month. However, hemangioma with diameter more than 4 cm, shedded in a period more than 3.5 month. No recurrence was observed in the follow up of 3 months to seven years.
  
  
  CONCLUSIONS
  Avoiding dissection of neck and repetitious operation, NBCA injection could be a safe, simple and effective therapy for laryngopharynx hemangioma.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of PLA, Beijing, 100853, China. Liweimin301@163.com
authors.forename: Weimin
authors.initials: W
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Feng
authors.forename: Jialing
authors.initials: J
authors.lastname: Wang
authors.forename: Wenming
authors.initials: W
authors.lastname: Wu
authors.forename: Liangfa
authors.initials: L
authors.lastname: Liu
authors.forename: Rongguang
authors.initials: R
authors.lastname: Wang
authors.forename: Dongyan
authors.initials: D
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004621:Embolization, Therapeutic; D004659:Enbucrilate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004659:Enbucrilate