Infectious uveitis in Thailand: serologic analyses and clinical features.
OBJECTIVE
To determine the seroprevalence of various infectious agents in Thai patients with uveitis.


METHODS
Prospective study of 101 consecutive patients with uveitis, 100 HIV-infected retinitis patients, and 100 nonuveitis controls.


RESULTS
Antibodies against T. gondii were detected in 31/101 non-HIV patients, mostly with posterior uveitis and focal retinitis, and were significantly higher than in other groups examined. Antibodies for T. pallidum and Leptospira were observed more frequently in patients with HIV-infected retinitis. Active tuberculosis in non-HIV patients was not found.


CONCLUSIONS
Seroprevalence of T. gondii antibodies in patients with non-HIV posterior uveitis was higher than in nonuveitis controls and HIV patients with retinitis.
Sirirungsi
Wasna
W
Division of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand. asmbi001@chiangmai.ac.th
Pathanapitoon
Kessara
K
Kongyai
Natedao
N
Weersink
Annemarie
A
de Groot-Mijnes
Jolanda D F
JD
Leechanachai
Pranee
P
Ausayakhun
Somsanguan
S
Rothova
Aniki
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000913:Antibodies, Protozoan / Q000097:blood; D002648:Child; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D007919:Leptospira / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D013785:Thailand / Q000453:epidemiology; D014122:Toxoplasma / Q000276:immunology; D014126:Toxoplasmosis, Ocular / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D014210:Treponema pallidum / Q000276:immunology; D014605:Uveitis / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology
D000907:Antibodies, Bacterial; D000913:Antibodies, Protozoan