title: Total synthesis of ciguatoxin.
abstract: Something fishy: Ciguatoxin (see structure) is one of the principal toxins involved in ciguatera poisoning and the target of a total synthesis involving the coupling of three segments. The key transformations in this synthesis feature acetylene-dicobalthexacarbonyl complexation.
authors.affiliation: Laboratory of Organic Chemistry, Bioagricultural Sciences, Nagoya University, Furocho, Chikusa 464-8601, Nagoya, Japan.
authors.forename: Akinari
authors.initials: A
authors.lastname: Hamajima
authors.forename: Minoru
authors.initials: M
authors.lastname: Isobe
mesh_terms: D000114:Acetylene / Q000737:chemistry; D002922:Ciguatoxins / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007536:Isomerism
chemical_list: D002922:Ciguatoxins; D000114:Acetylene