title: Effects of vascular bundle implantation on autograft, fresh-frozen allograft, and xenograft incorporation in a rabbit model.
abstract: This study examined the effects of vascular bundle implantation into a bone graft. Vascularized and nonvascularized autografts, allografts, and xenografts were placed inside defects in the proximal tibia in rabbits. Evaluation using radiographs, magnetic resonance imaging, bone scintigraphy, and microscopy showed autografts fused more rapidly than allografts and xenografts, and the majority of the vascularized grafts were incorporated completely. Autografts emerged as the gold standard. These findings indicate vessel implantation enhances and accelerates vascularization, new bone formation, and incorporation in autografts, allografts, and xenografts.
authors.affiliation: Department of Orthopedics and Traumatology, Private Onur Hospital, Silivri, Istanbul, Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Ozyurek
authors.forename: Gursel
authors.initials: G
authors.lastname: Leblebicioglu
authors.forename: Hasan
authors.initials: H
authors.lastname: Bilgili
authors.forename: Baris
authors.initials: B
authors.lastname: Kurum
authors.forename: Gokhan
authors.initials: G
authors.lastname: Gedikoglu
authors.forename: Tamer
authors.initials: T
authors.lastname: Atasever
authors.forename: Tugra
authors.initials: T
authors.lastname: Tacal
authors.forename: Mahmut Nedim
authors.initials: MN
authors.lastname: Doral
mesh_terms: D000818:Animals; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D015925:Cryopreservation; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D011817:Rabbits; D013977:Tibia / Q000098:blood supply* / Q000637:transplantation*; D013978:Tibial Fractures / Q000175:diagnosis / Q000601:surgery*; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014182:Transplantation, Autologous / Q000379:methods*; D014183:Transplantation, Heterologous / Q000379:methods*; D016896:Treatment Outcome