[Macular and multifocal electroretinography in the evaluation of the retinal macular region function in age-related macular degeneration].
The electrogenesis of the retinal macular region versus optic coherent tomographic data was studied in different forms of age-related macular degeneration (ARMD). A macular electroretinogram (M-ERG) and mixed ERG, multifocal ERG (mf-ERG), and optical coherent tomograms were recorded in 60 patients (112 eyes) aged 57 to 82 years who had ARMD. A significant moderate correlation was established between the averaged N1 amplitude of mf-ERG in the central rings and the M-ERG a-wave to a red stimulus, as well as between the averaged latency of an mfERG P1-component and the latency of the latency of b-wave and between the amplitudes of respective components. There was a significant reduction in the amplitude of the retinal macular region in confluent druzen. In focal atrophy of the retinal pigment epithelium (RPE), the amplitude decrease rate and extent varied from a significant reduction in M-ERG b-wave amplitude and a P1 decrease in the central hexagon to the significant reduction in the amplitude of M-ERG a- and b-wave components and mfERG N1 and P1 components in the foveal and parafoveal rings. M-ERG and mfERG changes in exudative ARMD were different in neuroepithelial and RPE detachments, retinal cystic changes and in varying activity of choroidal neovascularization.
Zol'nikova
I V
IV
Karlova
I Z
IZ
Ponomareva
E N
EN
Viadro
E V
EV
Zhamshinova
A M
AM
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D001330:Electronic Data Processing; D004596:Electroretinography / Q000379:methods*; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology / Q000503:physiopathology*; D008268:Macular Degeneration / Q000175:diagnosis / Q000503:physiopathology*; D008875:Middle Aged; D011379:Prognosis; D041623:Tomography, Optical Coherence