title: Comparison of different methods for detecting methicillin resistance in MRSA isolates belonging to international lineages commonly isolated in the American continent.
abstract: The aim of the present paper was to compare different methods for detecting methicillin resistance in Staphylococcus aureus. Among the isolates analyzed, 52 belonged to MRSA international lineages commonly detected in the American continent and 14 to sporadic MRSA clones. Both 30 microg-cefoxitin disk and PBP2a had 100% sensibility/specificity when the low-level heterogeneous isolates were tested and, thus, are highly recommended.
authors.affiliation: Federal University of Rio de Janeiro, Institute of Microbiology Professor Paulo de Góes, Center for Health Science, University City, Rio de Janeiro, Brazil.
authors.forename: Maria Cícera
authors.initials: MC
authors.lastname: Silva-Carvalho
authors.forename: Lenise Arneiro
authors.initials: LA
authors.lastname: Teixeira
authors.forename: Fabienne Antunes
authors.initials: FA
authors.lastname: Ferreira
authors.forename: Apoena
authors.initials: A
authors.lastname: Ribeiro
authors.forename: Bernadete Teixeira
authors.initials: BT
authors.lastname: Ferreira-Carvalho
authors.forename: Agnes Marie Sá
authors.initials: AM
authors.lastname: Figueiredo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D002440:Cefoxitin / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests / Q000379:methods*; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance / Q000235:genetics*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D009656:North America; D010068:Oxacillin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D013020:South America
chemical_list: D000900:Anti-Bacterial Agents; D002440:Cefoxitin; D008712:Methicillin; D010068:Oxacillin