Thymine dimerization in DNA model systems: cyclobutane photolesion is predominantly formed via the singlet channel.
UV-induced formation of cylcobutane pyrimidine dimers (CPD) in all thymine DNA models have been studied by femtosecond IR spectroscopy. CPDs are shown to form within approximately 1 ps during the decay of the initially excited (1)pi pi * state. The quantum yields phi(D)(ps) determined after the (1)pi pi * decay equal the final yield phi(D)(cw). This gives evidence for a predominance of the singlet channel in CPD formation.
Schreier
Wolfgang J
WJ
Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Munich Center for Integrated Protein Science CIPSM, Ludwig-Maximilians-Universität Munchen, Oettingenstr. 67, 80538 Munchen, Germany.
Kubon
Julia
J
Regner
Nadja
N
Haiser
Karin
K
Schrader
Tobias E
TE
Zinth
Wolfgang
W
Clivio
Pascale
P
Gilch
Peter
P
D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011740:Pyrimidine Dimers / Q000737:chemistry / Q000378:metabolism*; D013055:Spectrophotometry, Infrared; D013941:Thymine / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors; D014466:Ultraviolet Rays
D011740:Pyrimidine Dimers; D004247:DNA; D013941:Thymine