title: [Determination of ferulic acid in Fuan oral liquid by high-performance capillary electrophoresis].
abstract: OBJECTIVE
  To establish a quality control method of Fuan oral liquid.
  
  
  METHODS
  High-performance capillary electrophoresis (HPCE) was used to determine the content of feruild acid in Herba taraxaci, and thin-layer chromatography (TLC) was performed to identify Herba taraxaci and Bupleurum chinense. The condition of HPCE was optimized with a fuse silica capillary tube (70 microm x 60 cm) and 20 mmol/L sodium tetraborate buffer (pH9.18) at a constant voltage of 12 kV and temperature at 25 degrees celsius;, with the detection wavelength at 313 nm.
  
  
  RESULTS
  Clear spots were displayed on TLC. The calibration curve was linear in the range of 8-40 microg/ml for ferulic acid (Y=360.5-207.4, r=0.9997, n=5). The average recovery rate exceeded 95% with a RSD<3% (n=3).
  
  
  CONCLUSIONS
  This method is simple and specific with a good reproducibility for quality control of Fuan oral liquid.
authors.affiliation: Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou, China. lei@fimmu.com
authors.forename: Yi-Lei
authors.initials: YL
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Zheng
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yan
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
mesh_terms: D003373:Coumaric Acids / Q000032:analysis*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D019075:Electrophoresis, Capillary / Q000379:methods*; D011786:Quality Control
chemical_list: D003373:Coumaric Acids; D004365:Drugs, Chinese Herbal; C004999:ferulic acid