title: Ross and Ross-Konno procedures in infants, children and adolescents: a 13-year experience.
abstract: OBJECTIVE
  Due to hemodynamic performance and potential for growth of the pulmonary autograft, the Ross operation is considered to be the surgery of choice for irreparable aortic valve disease in pediatric patients. The study aim was to analyze the long-term clinical and echocardiographic results of the Ross operation.
  
  
  METHODS
  Between February 1993 and July 2006, 55 consecutive patients (mean age 10.0 +/- 6.2 years; range: 3 months to 18 years) underwent eithera Ross operation (n=46) or a Ross-Konno procedure (n=9). The underlying left ventricular outflow tract pathology was mainly congenital (n=47). Among patients, 23 (42%) had undergone a previous aortic valve procedure. Concomitant procedures were performed in 16 patients (29%). The Ross operation was performed as a root replacement in all cases; the mean cross-clamp time was 132 min (range: 100-188 min). The autograft diameter was indexed to the body surface area and compared to normal values. The mean follow up was 5.5 +/- 3.8 years, and was 100% complete.
  
  
  RESULTS
  There was one early death (2%) and two late deaths (4%). The actuarial patient survival was 93% at 10 years. None of the patients developed moderate or severe autograft regurgitation. All measured maximal root diameters were above the 90th percentile of normal aortic diameter, without correlation to autograft regurgitation. Five patients (9%) had a mean homograft gradient > or = 40 mmHg, and two (4%) were reoperated on. The freedom from reoperation for homograft degeneration was 91% at 10 years.
  
  
  CONCLUSIONS
  Autograft regurgitation after the Ross and Ross-Konno procedures is uncommon, and the risk of homograft degeneration appears low. Autograft dilatation is common but does not correlate with autograft regurgitation. When considering long-term freedom from autograft and homograft degeneration, the results of the present study confirm the Ross operation as the surgery of choice for irreparable aortic valve disease in infants, children and young adults.
authors.affiliation: Division of Cardiac Surgery, La Timone Children's Hospital, Marseille, France.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Piccardo
authors.forename: Olivier
authors.initials: O
authors.lastname: Ghez
authors.forename: Vlad
authors.initials: V
authors.lastname: Gariboldi
authors.forename: Alberto
authors.initials: A
authors.lastname: Riberi
authors.forename: Frederic
authors.initials: F
authors.lastname: Collart
authors.forename: Bernard
authors.initials: B
authors.lastname: Kreitmann
authors.forename: Dominique
authors.initials: D
authors.lastname: Metras
mesh_terms: D000293:Adolescent; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000151:congenital / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications; D011664:Pulmonary Valve / Q000637:transplantation*; D012086:Reoperation; D014182:Transplantation, Autologous; D014694:Ventricular Outflow Obstruction / Q000151:congenital / Q000601:surgery*