Nevus spilus with synchronous melanomas: case report and literature review.
BACKGROUND
Nevus spilus is a rare, acquired, and often large cutaneous lesion consisting of a light brown background macule containing varying numbers of small darker macular or papular areas.


OBJECTIVE
Nevus spilus may contain dysplastic melanocytic elements, and there are also reports of melanoma arising from nevus spilus. However, the absolute risk for malignant transformation is not well defined.


CONCLUSIONS
We discuss a case of synchronous melanomas arising from a nevus spilus and potential management recommendations based on a review of the pertinent literature.
Meguerditchian
Ari-Nareg
AN
Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. ari-nareg.meguerditchian@roswellpark.org
Cheney
Richard T
RT
Kane
John M
JM
D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D009506:Nevus / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery / Q000628:therapy