Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation.
The structures of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1, were elucidated by spectroscopic studies, including various NMR experiments. Pentacecilides have a common pentacyclic meroterpene core, which contains an aromatic ring and a delta-lactone ring.
Yamazaki
Hiroyuki
H
Graduate School of Pharmaceutical Sciences, Kitasato University, Shirokane, Tokyo, Japan.
Omura
Satoshi
S
Tomoda
Hiroshi
H
D000818:Animals; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D008970:Molecular Weight; D012717:Sesquiterpenes / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000960:Hypolipidemic Agents; D012717:Sesquiterpenes; C544291:pentacecilide A; C544292:pentacecilide B; C544290:pentacecilide C