Postoperative pain management after inguinal hernia repair: lornoxicam versus tramadol.
BACKGROUND
In this randomized and prospective study, we compared the analgesic effects of lornoxicam and tramadol in patients after inguinal hernia repair.


METHODS
A total of 160 patients were assigned in a randomized manner into two groups. Group L received 8 mg lornoxicam i.v. at the end of the operation, followed by 8 mg 12 h after the operation. Group T received 1 mg/kg tramadol at the end of the operation and every 6 h up to 24 h postoperatively. The visual analog scale (VAS) score was assessed at 0, 2, 4, 8, 12, and 24 h after surgery.


RESULTS
All patients completed the study. All vital signs were within normal ranges. The mean VAS score in Group L and in Group T was 21.66 +/- 14.64 and 19.75 +/- 11.82, respectively. No significant differences were found between groups with respect to VAS score. Eight (10%) patients in Group T had nausea.


CONCLUSIONS
Lornoxicam 8 mg i.v. and b.i.d., tramadol 1 mg/kg at the end of the surgery and every 6 h up to 24 h after inguinal hernia repair provided rapid and effective analgesia and was well tolerated.
Mentes
O
O
Department of General Surgery, Etimesgut Military Hospital, Etimesgut, Ankara, Turkey. onermentes@yahoo.com
Bagci
M
M
D000293:Adolescent; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy*; D017060:Patient Satisfaction; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011336:Probability; D011446:Prospective Studies; D012720:Severity of Illness Index; D014147:Tramadol / Q000008:administration & dosage*; D016896:Treatment Outcome; D055815:Young Adult
D000701:Analgesics, Opioid; D010894:Piroxicam; D014147:Tramadol; C059451:lornoxicam