Mouse Th17 cells: current understanding of their generation and regulation.
IL-17-expressing CD4(+) T cells have been recently recognized as a new subset of Th cells, namely Th17 cells. Considerable progress has been made in understanding the developmental regulation of mouse Th17 cells. Here, I summarize this knowledge and discuss on the relationship of Th17 with regulatory and follicular Th cells.
Dong
Chen
C
Department of Immunology, MD Anderson Cancer Center, Houston, TX 77030, USA. cdong@mdanderson.org
D000818:Animals; D002454:Cell Differentiation / Q000276:immunology; D016207:Cytokines / Q000276:immunology* / Q000378:metabolism; D020381:Interleukin-17 / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology* / Q000378:metabolism; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism
D016207:Cytokines; D020381:Interleukin-17