title: Treatment with OK-432 for persistent congenital chylothorax in newborn infants resistant to octreotide.
abstract: Chylothorax is a relatively uncommon condition defined as an abnormal collection of lymphatic fluid within the pleural space. We are reporting the use of OK-432 for treatment of prolonged idiopathic congenital chylothorax in 2 newborn infants who failed to respond to conservative medical therapy, including octreotide injection.
authors.affiliation: The Department of Pediatrics, Nagara Medical Center, Gifu 502-8558, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Matsukuma
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Aoki
authors.forename: Miho
authors.initials: M
authors.lastname: Sakai
authors.forename: Norio
authors.initials: N
authors.lastname: Kawamoto
authors.forename: Hiroh
authors.initials: H
authors.lastname: Watanabe
authors.forename: Shigeki
authors.initials: S
authors.lastname: Iwagaki
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kawabata
authors.forename: Naomi
authors.initials: N
authors.lastname: Kondo
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Uchida
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002097:C-Reactive Protein / Q000032:analysis; D015505:Chest Tubes; D002916:Chylothorax / Q000151:congenital / Q000188:drug therapy* / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007322:Instillation, Drug; D008297:Male; D015282:Octreotide / Q000008:administration & dosage; D010844:Picibanil / Q000008:administration & dosage / Q000627:therapeutic use*; D010996:Pleural Effusion / Q000188:drug therapy; D012121:Respiration, Artificial; D017211:Treatment Failure
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil; D002097:C-Reactive Protein; D015282:Octreotide