title: Acute abdomen as initial presentation of gestational choriocarcinoma.
abstract: Choriocarcinoma is the most malignant tumor of gestational trophoblastic neoplasia. Choriocarcinoma presenting as postpartum hemorrhage and spontaneous uterine perforation with intra-abdominal hemorrhage is very rare. We present a 29-year-old woman with spontaneous uterine rupture due to choriocarcinoma following a live birth pregnancy. The long time interval (2 years) between the previous live birth pregnancy and the diagnosis of the disease, the acute onset of the disease by uterine rupture as the first symptom and the negative urine hCG test are presented and discussed in this case report.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Liberis
authors.forename: Sofia
authors.initials: S
authors.lastname: Bouchlariotou
authors.forename: Alexandros
authors.initials: A
authors.lastname: Ammari
authors.forename: Afroditi
authors.initials: A
authors.lastname: Psillaki
authors.forename: Maritsa
authors.initials: M
authors.lastname: Ntatidou
authors.forename: Efthimios
authors.initials: E
authors.lastname: Sivridis
authors.forename: Valentina
authors.initials: V
authors.lastname: Dislian
authors.forename: Nikoleta
authors.initials: N
authors.lastname: Koutlaki
mesh_terms: D000006:Abdomen, Acute / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007044:Hysterectomy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014595:Uterine Perforation / Q000473:pathology / Q000601:surgery
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human