title: Asymmetric Suzuki-Miyaura coupling in water with a chiral palladium catalyst supported on an amphiphilic resin.
abstract: You oughta use water: Broad functional-group (FG) tolerance was observed for the title coupling of aryl halides (X = Cl, Br, I) and aryl boronic acids to give biaryl compounds with up to 94% ee. The chiral imidazoindole phosphine-palladium catalyst supported on an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin could be recycled readily.
authors.affiliation: Institute for Molecular Science and The Graduate School for Advanced Studies, Myodaiji, Okazaki, Aichi 444-8787, Japan. uo@ims.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uozumi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Matsuura
authors.forename: Takayasu
authors.initials: T
authors.lastname: Arakawa
authors.forename: Yoichi M A
authors.initials: YM
authors.lastname: Yamada