Determination of cyanide in blood by reaction head-space gas chromatography.
A method describing determination of cyanide in blood by head-space gas chromatography with electron capture detector was reported. The method involves transformation of cyanide into cyanogen chloride by reacting hydrogen cyanide with chloramine-T on a stick of filter paper in the space above the blood in the head-space vial. The recovery was 84-96% and the coefficient of variation was 3.3-7.2%. The limit of quantitation was about 0.01 mg cyanide/l.
Felby
Søren
S
Institute of Forensic Medicine, University of Southern Denmark, Winsløwparken 17, 5000, Odense C, Denmark. sfelby@health.sdu.dk
D002700:Chloramines; D002849:Chromatography, Gas / Q000379:methods*; D003486:Cyanides / Q000097:blood*; D053593:Forensic Toxicology / Q000379:methods; D006801:Humans; D007202:Indicators and Reagents; D014105:Tosyl Compounds
D002700:Chloramines; D003486:Cyanides; D007202:Indicators and Reagents; D014105:Tosyl Compounds; C016300:chloramine-T; C014430:cyanogen chloride