Biological and microcalorimetric studies of the toxic effect of organoarsenic(V) compounds to wild strain of Bacillus thuringiensis.
Microcalorimetric and biological methods were carried out to determine the toxicity of dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA) to wild strain of Bacillus thuringiensis. Thermokinetic parameters were obtained from the power-time curves, showing that the peak-heat output power, total heat output, and number of colonies decreased with the increases in concentration of DMA and MMA. In addition, the generation time and peak maximal time increased with the increases in the dosage of DMA and MMA. The half inhibitory concentrations of DMA and MMA were 99.02 and 142.02 microg mL(-1), respectively for the wild strain of B. thuringiensis. DMA shows higher toxicity to bacteria than MMA. The toxicity resistance of B. thuringiensis against organoarsenic(V) is quite high for the wild strain. Our work demonstrates that microcalorimetry is a very sensitive, simple, and useful technique for in vitro investigation of the toxic effect of organoarsenic(V) on microbial activity.
Russel
Mohammad
M
School of Environmental Studies & Key Laboratory of Biogeology and Environmental Geology, Chinese Ministry of Education and Sino-Hungarian Joint Laboratory of Environmental Science and Health, China University of Geosciences, Wuhan, People's Republic of China.
Yao
Jun
J
Chen
Huilun
H
Wang
Fei
F
Zhou
Yong
Y
Zhuang
Rensheng
R
Choi
Martin M F
MM
Ceccanti
Brunello
B
Trebse
Polonca
P
Zaray
Gyula
G
D000818:Animals; D001413:Bacillus thuringiensis / Q000187:drug effects* / Q000254:growth & development; D002101:Cacodylic Acid / Q000633:toxicity*; D002151:Calorimetry; D015169:Colony Count, Microbial; D004305:Dose-Response Relationship, Drug; D006540:Herbicides / Q000633:toxicity*; D006358:Hot Temperature
D006540:Herbicides; D002101:Cacodylic Acid