Palladium-catalyzed three-component cascade cyclization reaction of bisallenes with propargylic carbonates and organoboronic acids: efficient construction of cis-fused bicyclo[4.3.0]nonenes.
A bicycle built for two: The title reaction affords cis-fused bicyclo[4.3.0]nonenes from readily available 1,5-bisallenes with structurally diverse propargylic carbonates and arylboronic acids (see scheme; X = NTs, C(E(1))(2) with E(1) = CO(2)Bn, SO(2)Ph, dba = trans,trans-dibenzylidenacetone). The reaction may involve a sequential oxidative addition, two different types of three carbopalladations, and a Suzuki-type coupling.
Shu
Wei
W
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, PR China.
Jia
Guochen
G
Ma
Shengming
S