title: One-pot synthesis of cyclic antifreeze glycopeptides.
abstract: The first cyclic glycopeptides exhibiting significant antifreeze activity by forming hexagonal-bipyramidal ice crystals, denoted cyclic antifreeze glycopeptides (cyclic AFGPs), were constructed by a one-pot synthesis based on the controlled cyclization reaction of pre-formed small linear glycopeptides.
authors.affiliation: Laboratory of Advanced Chemical Biology, Graduate School of Advanced Life Science, and Frontier Research Center for Post-Genome Science and Technology, Hokkaido University, Sapporo, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Hachisu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hinou
authors.forename: Manabu
authors.initials: M
authors.lastname: Takamichi
authors.forename: Sakae
authors.initials: S
authors.lastname: Tsuda
authors.forename: Shuhei
authors.initials: S
authors.lastname: Koshida
authors.forename: Shin-Ichiro
authors.initials: S
authors.lastname: Nishimura
mesh_terms: D021301:Antifreeze Proteins / Q000138:chemical synthesis*; D002942:Circular Dichroism; D010456:Peptides, Cyclic / Q000138:chemical synthesis*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D021301:Antifreeze Proteins; D010456:Peptides, Cyclic