Pseudoxanthoma elasticum.
A 55-year-old man with progressive loss of vision was referred for dermatology consultation for the evaluation of his skin lesions. The cutaneous examination of the patient revealed multiple small yellow papules, coalescing into plaques, on his neck, axillae and periumbilical regions. He also had redundant skin folds on the axillae. His peripheral pulses and blood pressure were normal. Angioid streaks were found in the ocular fundi. A skin biopsy specimen of the papule showed fragmentation of elastic fibers as well as calcification in the dermis. Given the clinical manifestations and the histopathologic findings, the patient's illness was diagnosed as pseudoxanthoma elasticum. The patient was then sent to undergo a thorough cardiovascular evaluation.
Moreira
Angela Puccini
AP
Universidade Federal Fluminense, Hospital Universitário Antônio Pedro - Serviço de Dermatologia, Niterói, Rio de Janeiro, Brazil. angelapuccini@bol.com.br
Feijó
Flávia Sousa
FS
Pinto
Jane Marcy Neffá
JM
Martinelli
Isabella Loureiro
IL
Rochael
Mayra Carrijo
MC
D006801:Humans; D008297:Male; D008875:Middle Aged; D011561:Pseudoxanthoma Elasticum / Q000473:pathology