title: A new metabolic scoring system for analyzing the risk of hypertensive disorders of pregnancy.
abstract: OBJECTIVE
  The aim of this study was to investigate the relationship between some components of metabolic syndrome (MS) and pregnancy induced hypertension (PIH).
  
  
  METHODS
  Forty-one patients with PIH (gestational hypertension or preeclampsia) after 32 weeks of gestation were compared with 97 normotensive pregnant women. Metabolic scores (0-4) were created using standard deviations in normotensive cases: mean level + 1SD for BMI (>31 kg/m(2)), mean level + 1SD for triglyceride (>287 mg/dl), mean level + 1SD for fasting serum glucose (>90 mg/dl)) and mean level - 1SD for HDL (<48 mg/dl).
  
  
  RESULTS
  The mean values for BMI (31.6 +/- 5.7 vs. 27.7 +/- 3.6; P < 0.0001), fasting triglyceride (341 +/- 129 vs. 220.7 +/- 67; P < 0.0001) and glucose (87.5 +/- 17.1 vs. 79.6 +/- 10.4; P = 0.0009) were higher in hypertensive group. The proportions of the women with a positive result for each of the components were significantly higher in the group of PIH. The percentage of the cases having 2 (35.2 vs. 8.2%; P = 0.0002) and 3 or more (27 vs. 4.1%; P = 0.0003) components of MS was higher in the hypertensive group and the percentage of the cases with none of these factors was high in the normotensive group (10.8 vs. 56.7%; P < 0.0001).
  
  
  CONCLUSIONS
  The presence of multiple components of MS may be a risk factor in the development of PIH. New scoring systems according to the gestational age might be useful in analyzing the risk of PIH.
authors.affiliation: Department of Gynecology and Obstetrics, Haseki Training and Research Hospital, Istanbul, Turkey. banudane@yahoo.com
authors.forename: Banu
authors.initials: B
authors.lastname: Dane
authors.forename: Cem
authors.initials: C
authors.lastname: Dane
authors.forename: Murat
authors.initials: M
authors.lastname: Kiray
authors.forename: Macit
authors.initials: M
authors.lastname: Koldas
authors.forename: Ahmet
authors.initials: A
authors.lastname: Cetin
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000378:metabolism*; D008075:Lipoproteins, HDL / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000378:metabolism*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008075:Lipoproteins, HDL; D014280:Triglycerides