Enantio- and diastereoselective tandem zn-promoted brook rearrangement/ene-allene carbocyclization reaction.
The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn-Brook rearrangement and either the Zn-ene-allene or Zn-yne-allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation.
Unger
Rozalia
R
Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry, and the Lise Meitner-Minerva Center for Computational Quantum Chemistry, Technion-Israel Institute of Technology, 32 000 Haifa, Israel.
Weisser
Fritz
F
Chinkov
Nicka
N
Stanger
Amnon
A
Cohen
Theodore
T
Marek
Ilan
I