The history of status epilepticus and its treatment.
Despite the fact that status epilepticus was been recognized since antiquity, its existence was largely ignored until the mid-nineteenth century. In this review we cover the medical literature of status epilepticus from the late nineteenth century until the early 1970s when the modern era of status epilepticus began. We pay particular attention to the impact of the ILAE and its principal members on the understanding and awareness of status epilepticus. We also cover the evolution of treatment regimens advocated for status epilepticus from the late nineteenth century to the early 1970s when the benzodiazepines were established as first line treatments.
Neligan
Aidan
A
UCL Institute of Neurology, University College London, London, United Kingdom.
Shorvon
Simon D
SD
D000927:Anticonvulsants / Q000266:history* / Q000627:therapeutic use; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D013226:Status Epilepticus / Q000266:history* / Q000628:therapy
D000927:Anticonvulsants