title: Diabetic muscle infarction in association with terlipressin therapy: a case report.
abstract: Diabetic muscle infarction (DMI) is a rare complication that often exists in long-standing diabetic patients. Clinically, it presents with pain, swelling and sometimes a palpable mass, and is often misdiagnosed as soft tissue infection. The athogenesis of DMI is uncertain. We present the case of a type 2 diabetic patient with liver cirrhosis who was diagnosed with muscle infarction after being treated with terlipressin for gastrointestinal bleeding. This 45-year-old male complained of increasing pain in his right posterior thigh after treatment with terlipressin for 2 days. He was initially diagnosed with soft tissue infection, but he responded poorly to antibiotic treatment. Magnetic resonance imaging suggested acute muscle infarction. We performed a muscle biopsy and the pathologist reported that the muscle was necrotic. After 5 days of bed rest, the patient was able to walk and was discharged uneventfully.
authors.affiliation: Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
authors.forename: Yu-Hung
authors.initials: YH
authors.lastname: Chang
authors.forename: Feng-Chieh
authors.initials: FC
authors.lastname: Yen
authors.forename: Ming-Chia
authors.initials: MC
authors.lastname: Hsieh
authors.forename: Kun-Der
authors.initials: KD
authors.lastname: Lin
authors.forename: Shyi-Jang
authors.initials: SJ
authors.lastname: Shin
authors.forename: Shih-Chieh
authors.initials: SC
authors.lastname: Hsin
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007238:Infarction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008236:Lypressin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D000077585:Terlipressin
chemical_list: D008236:Lypressin; D000077585:Terlipressin