Biliary dilatation secondary to lithiasis in a child affected by Langerhans' cell histiocytosis.
Langerhans' cell histiocytosis (LCH) is a disease of unknown pathogenesis, caused by clonal proliferation of Langerhans' cells. Liver involvement results in a cholangiopathy, which has the radiologic appearance of sclerosing cholangitis. Only 1 case of obstructive jaundice due to common bile duct stone in a patient with LCH has been described. We present a case of a 31-month-old child with LCH and liver involvement on the waiting list for liver transplantation. During the follow-up, there was a rapid onset of jaundice due to sludge and lithiasis. The patient was treated first with an endoscopic biliary plastic stent and then with percutaneous biliary drainage and bilioenteric anastomosis.
Caruso
Settimo
S
Department of Radiology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT), Palermo, Italy.
Miraglia
Roberto
R
Spada
Marco
M
Luca
Angelo
A
Gridelli
Bruno
B
D000714:Anastomosis, Surgical; D001649:Bile Duct Diseases / Q000175:diagnosis / Q000209:etiology*; D002675:Child, Preschool; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis / Q000209:etiology*; D020347:Lithiasis / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography