Iron salts in the catalyzed synthesis of 5-substituted 1H-tetrazoles.
Clicking iron: Cheap and environmentally friendly [Fe(OAc)(2)] is used for the catalysis of cycloadditions between aryl nitriles and trimethylsilyl azide to prepare substituted 1H-tetrazoles in good yield (see scheme).
Bonnamour
Julien
J
Institute for Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52056 Aachen, Germany.
Bolm
Carsten
C
D002384:Catalysis; D003500:Cyclization; D005290:Ferric Compounds / Q000737:chemistry*; D013777:Tetrazoles / Q000138:chemical synthesis* / Q000737:chemistry
D005290:Ferric Compounds; D013777:Tetrazoles; C045574:1H-tetrazole; C047434:ferric acetate