title: [Bilateral thalamic glioma in an adult: a case report and review of the literature].
abstract: We report a case of a 36-year-old woman who had a rare bilateral thalamic glioma (BTG). She complained of memory disorder T1-weighted magnetic resonance imaging revealed enlarged bilateral thalami with homogenous isointensity and no contrast enhancement. Histological examination of the biopsy specimen identified diffuse astrocytoma (WHO grade II). BTG is a rare variant of thalamic neoplasms, which can be distinguished clinically and radiologically from other gliomas. In most of the reported cases, the presenting symptoms were cognitive impairment varying from personality changes to frank dementia. Death usually occurs within two years after onset, independently of adjuvant therapy such as radiotherapy and chemotherapy. On neuroimaging, all of the BTG had a similar appearance, with both thalami being symmetrically enlarged. Our patient has been given radiotherapy and concominant and adjuvant temozolomide in Stupp's regimen. At the time of this writing (5 months after the consultation), there are no neurological symptoms, and no changes on neuroimaging.
authors.affiliation: Department of Neurosurgery, Okazaki Municipal Hospital, 3-1 Kouryuuzi Gosyogo, Okzaki-shi, Aichi 444-8553, Japan.
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Iwami
authors.forename: Toru
authors.initials: T
authors.lastname: Arima
authors.forename: Fumiharu
authors.initials: F
authors.lastname: Ooka
authors.forename: Takumi
authors.initials: T
authors.lastname: Asai
authors.forename: Masao
authors.initials: M
authors.lastname: Tambara
authors.forename: Toru
authors.initials: T
authors.lastname: Takaoka
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D013788:Thalamus