title: Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor in Meckel's diverticulum; an unusual association.
abstract: BACKGROUND
  Coexistence of gastrointestinal stromal tumor with synchronous or metachronous colorectal cancer represents a phenomenon with increasing number of relative reports in the last 5 years. Synchronous occurence of GISTs with other gastrointestinal tumors of different histogenesis presents a special interest. We herein report a case of GIST in Meckel's diverticulum synchronous with colorectal adenocarcinoma.
  
  
  METHODS
  A 69 year old man, presented with abdominal distension and anal bleeding on defecation. Colonoscopy revealed colorectal cancer and a low anterior resection was performed, during which a tumor in Meckel's diverticulum was discovered. Histologic examination revealed GIST in Meckel's diverticulum and a rectosigmoid adenocarcinoma.
  
  
  CONCLUSIONS
  Whenever GIST is encountered, the surgeon should be alert to recognize a possible coexistent tumor with different histological origin. Correct diagnosis of synchronous tumors of different origin is the cornerstone of treatment.
authors.affiliation: Department of Surgery, Interbalkan European Medical Center, Thessaloniki, Greece. dr.ckosmidis@gmail.com
authors.forename: Christopher
authors.initials: C
authors.lastname: Kosmidis
authors.forename: Christopher
authors.initials: C
authors.lastname: Efthimiadis
authors.forename: Sofia
authors.initials: S
authors.lastname: Levva
authors.forename: George
authors.initials: G
authors.lastname: Anthimidis
authors.forename: Sofia
authors.initials: S
authors.lastname: Baka
authors.forename: Marios
authors.initials: M
authors.lastname: Grigoriou
authors.forename: Ioanna
authors.initials: I
authors.lastname: Tzeveleki
authors.forename: Maria
authors.initials: M
authors.lastname: Masmanidou
authors.forename: Thomas
authors.initials: T
authors.lastname: Zaramboukas
authors.forename: Georgios
authors.initials: G
authors.lastname: Basdanis
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008467:Meckel Diverticulum / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery