Current synthesis of triterpene saponins.
Triterpene saponins are a structurally and biologically diverse class of glycoconjugates of triterpenes that are widely distributed in terrestrial plants and some marine organisms. Current synthesis of these complex glycoconjugates has been discussed, whereupon the stereocontrolled glycosylation, global protection/deprotection, and the total synthesis of four unusual triterpene saponins are highlighted.
Yu
Biao
B
State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China. byu@mail.sioc.ac.cn
Sun
Jiansong
J
D006027:Glycosides / Q000138:chemical synthesis / Q000737:chemistry; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D011134:Polysaccharides / Q000138:chemical synthesis / Q000737:chemistry; D012503:Saponins / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry*
D006027:Glycosides; D011134:Polysaccharides; D012503:Saponins; D014315:Triterpenes; C507776:anemoclemoside B; C529635:lobatoside E; C413246:oleanane; D009828:Oleanolic Acid