Elaeagnoside, chymotrypsin inhibiting steroidal glucoside from Elaeagnus orientalis.
Elaeagnoside (1), a new steroidal glucoside, has been isolated from the chloroform fraction of Elaeagnus orientalis along with beta-sitosterol and 12-hydroxy-8,10-octadecadienoic acid. The structure of 1 has been elucidated with the help of chemical and spectral studies. It showed significant inhibitory activity against the enzyme chymotrypsin.
Ayaz
Muhammad
M
International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Riaz
Muhammad
M
Malik
Abdul
A
Ahmad
Ejaz
E
Fatima
Itrat
I
Arif Lodhi
Muhammad
M
Chaudhary
Muhammad Iqbal
MI
D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D031263:Elaeagnaceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D012503:Saponins / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry*
D005960:Glucosides; D012503:Saponins; D013256:Steroids; C540881:elaeagnoside; D002918:Chymotrypsin