Comparison of retinal degeneration in the normal goldfish and the megalophthalmic black moor goldfish after optic nerve transection and lens extraction.
A comparison in retinal degeneration was studied in the normal goldfish and the megalophthalmic goldfish after optic nerve transection or lens extraction by the TUNEL (Terminal transferase-mediated dUTP nick end labeling) technique. A significant number of TUNEL positive cells appeared in both cases 7 days after injury, with a more prominent result in the megalophthalmic eye. Lens extraction, had less apoptotic cell death in the experimental retinas.
Ying
Xi
X
Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Wai
Maria S M
MS
Wang
Yi
Y
Lau
Jeanie P C
JP
Forster
Elizabeth Lucy
EL
Yew
David T
DT
D000818:Animals; D017209:Apoptosis; D006054:Goldfish; D020287:In Situ Nick-End Labeling; D007908:Lens, Crystalline / Q000601:surgery*; D020221:Optic Nerve Injuries / Q000473:pathology*; D012160:Retina / Q000473:pathology*; D012162:Retinal Degeneration / Q000473:pathology*