title: Thymine dimerization in DNA model systems: cyclobutane photolesion is predominantly formed via the singlet channel.
abstract: UV-induced formation of cylcobutane pyrimidine dimers (CPD) in all thymine DNA models have been studied by femtosecond IR spectroscopy. CPDs are shown to form within approximately 1 ps during the decay of the initially excited (1)pi pi * state. The quantum yields phi(D)(ps) determined after the (1)pi pi * decay equal the final yield phi(D)(cw). This gives evidence for a predominance of the singlet channel in CPD formation.
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Munich Center for Integrated Protein Science CIPSM, Ludwig-Maximilians-Universität Munchen, Oettingenstr. 67, 80538 Munchen, Germany.
authors.forename: Wolfgang J
authors.initials: WJ
authors.lastname: Schreier
authors.forename: Julia
authors.initials: J
authors.lastname: Kubon
authors.forename: Nadja
authors.initials: N
authors.lastname: Regner
authors.forename: Karin
authors.initials: K
authors.lastname: Haiser
authors.forename: Tobias E
authors.initials: TE
authors.lastname: Schrader
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Zinth
authors.forename: Pascale
authors.initials: P
authors.lastname: Clivio
authors.forename: Peter
authors.initials: P
authors.lastname: Gilch
mesh_terms: D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011740:Pyrimidine Dimers / Q000737:chemistry / Q000378:metabolism*; D013055:Spectrophotometry, Infrared; D013941:Thymine / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors; D014466:Ultraviolet Rays
chemical_list: D011740:Pyrimidine Dimers; D004247:DNA; D013941:Thymine