title: Trans-nasal injection of botulinum toxin.
abstract: BACKGROUND
  Office-based laryngeal injection for the treatment of a variety of voice disorders is an established practice. Various methods of delivery to the vocal folds are in practice.
  
  
  OBJECTIVE
  We present a simple and repeatable method of injecting botulinum toxin into the larynx.
  
  
  METHODS
  Botulinum toxin A (Botox) was delivered into the larynx using a channelled fibre-optic laryngoscope under local anaesthetic, in an office setting.
  
  
  RESULTS
  Seven patients received regular botulinum toxin injections, via our preferred method. The treatment intervals and dosage regime varied depending on patient requirements. The procedure was carried out in an office setting, with minimal discomfort and inconvenience to the patient.
  
  
  CONCLUSIONS
  We present a method of botulinum toxin delivery to the larynx which is simple, easily repeatable and simply learnt by the otolaryngologist familiar with fibre-optic laryngoscope usage. This method is also comfortable and convenient for the patient.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, Scotland, UK. drakhtarhussain93@yahoo.co.uk
authors.forename: A
authors.initials: A
authors.lastname: Hussain
authors.forename: G
authors.initials: G
authors.lastname: Thiel
authors.forename: M
authors.initials: M
authors.lastname: Shakeel
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D055154:Dysphonia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D020704:Laryngoscopes; D007830:Larynx / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D019274:Botulinum Toxins, Type A