title: Next generation calcium phosphate-based biomaterials.
abstract: It has been close to a century since calcium phosphate materials were first used as bone graft substitutes. Numerous studies conducted in the last two decades have produced a wealth of information on the chemistry, in vitro properties, and biological characteristics of granular calcium phosphates and calcium phosphate cement biomaterials. An in depth analysis of several key areas of calcium phosphate cement properties is presented with the aim of developing strategies that could lead to break-through improvements in the functional efficacies of these materials.
authors.affiliation: Paffenbarger Research Center, American Dental Association Foundation NIST, Gaithersburg, MD 20899, USA. laurence.chow@nist.gov
authors.forename: L C
authors.initials: LC
authors.lastname: Chow
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D001843:Bone Cements / Q000737:chemistry; D018786:Bone Substitutes / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry*; D003764:Dental Materials / Q000737:chemistry; D006801:Humans
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; D003764:Dental Materials; C020243:calcium phosphate