title: Velopharyngeal stenosis, a late complication of radiotherapy.
abstract: Choanal stenosis has recently been recognized as a late complication of radiation therapy for nasopharyngeal carcinoma. The management of velopharyngeal stenosis is challenging with high risk of restenosis. We report a case of velopharyngeal stenosis post-radiotherapy and illustrated the use of mitomycin-C to prevent restenosis. Mitomycin-C application has being shown useful adjunct to surgical technique in managing nasopharyngeal stenosis for surgeons.
authors.affiliation: Department of Otorhinolaryngology, Sarawak General Hospital, Kuching, Sarawak, Malaysia.
authors.forename: Siew Ching
authors.initials: SC
authors.lastname: Lee
authors.forename: Ing Ping
authors.initials: IP
authors.lastname: Tang
authors.forename: Avatar
authors.initials: A
authors.lastname: Singh
authors.forename: S Selva
authors.initials: SS
authors.lastname: Kumar
authors.forename: Shashinder
authors.initials: S
authors.lastname: Singh
mesh_terms: D000287:Administration, Topical; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002754:Choanal Atresia / Q000175:diagnosis* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007442:Intubation, Intratracheal; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D010609:Pharyngeal Muscles / Q000528:radiation effects*; D011832:Radiation Injuries / Q000175:diagnosis* / Q000628:therapy; D012008:Recurrence; D019233:Retreatment; D015607:Stents
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin