title: Cerebellar schistosomiasis: a case report with clinical analysis.
abstract: The authors report here a rare case of cerebellar schistosomiasis identified by pathological diagnosis, lacking extracranial involvement. The clinical symptoms included headache, dizziness, and nausea. Studies in blood were normal and no parasite eggs were detected in stool. Computed tomography of brains showed hypodense signal, and magnetic resonance imaging showed isointense signal on T1-weighted images, hyperintense signal on T2-weighted images, and intensely enhancing nodules in the right cerebellum after intravenous administration of gadolinium. A high-grade glioma was suspected, and an operation was performed. The pathologic examination of the biopsy specimen revealed schistosomal granulomas scattered within the parenchyma of the cerebellum. The definitive diagnosis was cerebellar schistosomiasis japonica. A standard use of praziquantel and corticosteroid drugs was applied, and the prognosis was good. When the pattern of imaging examinations is present as mentioned above, a diagnosis of brain schistosomiasis should be considered.
authors.affiliation: Department of Neurology and Functional Neurosurgery, West China Fourth Hospital of Sichuan University, Chengdu, PR China. zeonguton@yahoo.cn
authors.forename: Heng
authors.initials: H
authors.lastname: Wan
authors.forename: Ding
authors.initials: D
authors.lastname: Lei
authors.forename: Qing
authors.initials: Q
authors.lastname: Mao
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000469:parasitology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D011859:Radiography; D012549:Schistosoma japonicum / Q000302:isolation & purification; D012554:Schistosomiasis japonica / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D011223:Praziquantel