title: Biology of allograft incorporation.
abstract: The use of implantation of allograft tissue in sports medicine has risen steadily over the last decade. Allograft tissues offer several advantages over autografts, including reduced donor-site morbidity and decreased operative time, and in some instances, no autograft option exists. However, with allografts, there is a small risk of disease transmission, immunologic rejection, and decreased biologic incorporation. Several techniques to limit these pitfalls and maximize graft incorporation are available, however. This chapter takes an in-depth look at the biology of allograft incorporation and how these techniques affect graft incorporation.
authors.affiliation: UCLA Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, CHS, Box 956902, Los Angeles, CA 90095-6902, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Eagan
authors.forename: David R
authors.initials: DR
authors.lastname: McAllister
mesh_terms: D016025:Bone Transplantation; D006801:Humans; D008592:Menisci, Tibial / Q000601:surgery / Q000637:transplantation*; D010007:Osteochondritis / Q000601:surgery; D013178:Sports Medicine; D013709:Tendon Transfer; D014184:Transplantation, Homologous / Q000276:immunology / Q000379:methods / Q000502:physiology