title: [Incidence of type 1 diabetes mellitus in children: results from the population registry of the Madrid Region, 1997-2005].
abstract: OBJECTIVE
  Incidence of type 1 diabetes mellitus (DM) varies importantly worldwide, including European countries, and even among regions within a country. The aim of this study is to describe the incidence of type 1 DM in the Madrid Region.
  
  
  METHODS
  We included 1130 new cases of type 1 DM in children below 15 years of age, which were notified to the diabetes registry from January, 1997 to December, 2005. Case ascertainment was evaluated through the capture-recapture method. The data was analysed using Poisson regression models.
  
  
  RESULTS
  The incidence rate in this period was 15.9/100,000 persons-years (95% confidence interval, 15.0-16.8). Completeness of ascertainment was 82%. The incidence by age group was 12.1 (0-4 years), 18.2 (5-9 years) and 17.4 by 100,000 persons-years (10-14 years). The incidence data showed no significant changes in the studied period. We observed a seasonal variation in the incidence, with the greatest incidence in the cold months.
  
  
  CONCLUSIONS
  The estimated incidence of type 1 DM ranks in an intermediate position with regard to that estimated more recently in other Spanish regions. During the period 1997-2005, the incidence has maintained stable in the Madrid Region.
authors.affiliation: Dirección General de Salud Pública y Alimentación, Madrid, España. belen.zorilla@salud.madrid.org
authors.forename: Belén
authors.initials: B
authors.lastname: Zorrilla Torras
authors.forename: José Luis
authors.initials: JL
authors.lastname: Cantero Real
authors.forename: Raquel
authors.initials: R
authors.lastname: Barrios Castellanos
authors.forename: Joaquín
authors.initials: J
authors.lastname: Ramírez Fernández
authors.forename: Jesús
authors.initials: J
authors.lastname: Argente Oliver
authors.forename: Angeles
authors.initials: A
authors.lastname: González Vergaz
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012042:Registries; D013030:Spain; D014505:Urban Population