title: [Magnetic resonance myocardial perfusion imaging for evaluating myocardial viability after myocardial infarction].
abstract: OBJECTIVE
  To assess the value of magnetic resonance (MR) myocardial perfusion imaging (MRMPI) in evaluating the myocardial viability in patients with myocardial infarction.
  
  
  METHODS
  MRMPI was performed in 51 patients with myocardial infarction using a 1.5 T MR scanner. All the patients were examined using IR-turbo FLASH sequence during the first-pass and delayed phase 5-30 min after injection of 0.1 mmol/kg Gd-DTPA at the rate of 4 ml/s. The short axis images were acquired during the first-pass, and both the short axis and long axis images were obtained during the delayed phase. The left ventricular wall on the short-axis slice was divided into 8 segments. A correlative study of the results of the rest and stress (99m)Tc single photon emission computed tomography (SPECT) was carried out in 21 patients.
  
  
  RESULTS
  In the 51 patients with myocardial infarction, 42(82.3%) showed hypoperfusion during the first-pass imaging and 50(98%) had delayed hyperenhancement. In the 21 patients receiving SPECT, 48 nonviable segments was detected among the 168 segments scanned by (99m)TcSPECT, and MRMPI showed delayed hyperenhancement in all the infracted areas. Of the 120 viable segments detected by rest and stress (99m)Tc SPECT, 97 segments (80.8%) were found to be free of delayed hyperenhancement by MRMPI. With the rest and stress (99m)Tc SPECT as the reference, the sensitivity and the specificity of MRMPI were 100.0% and 80.8%, respectively.
  
  
  CONCLUSIONS
  MRMPI allows effective identification of the myocardial viability and nonviability as well as the severity and extent of the myocardial infraction.
authors.affiliation: Depatment of Pathology, Southern Medical University, Guangzhou, China. zhihua_meng@163.com
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Meng
authors.forename: Yan-Qing
authors.initials: YQ
authors.lastname: Ding
authors.forename: Xian-Yue
authors.initials: XY
authors.lastname: Quan
authors.forename: Xin
authors.initials: X
authors.lastname: Xu
authors.forename: Liang-Qiou
authors.initials: LQ
authors.lastname: Tang
authors.forename: Shao-Chun
authors.initials: SC
authors.lastname: Ma
authors.forename: Gao-Sheng
authors.initials: GS
authors.lastname: Pan
authors.forename: Yu-Ling
authors.initials: YL
authors.lastname: Lu
authors.forename: Zhen-Shong
authors.initials: ZS
authors.lastname: Chen
authors.forename: Shu-Fei
authors.initials: SF
authors.lastname: Lei
authors.forename: Ang
authors.initials: A
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D055414:Myocardial Perfusion Imaging / Q000379:methods; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019786:Gadolinium DTPA