Percutaneous intragastric catheter (PIC) for administration of an unpalatable substance to large animals.
We studied an easy and reliable technique for administration of an unpalatable substance to large animals. There were three groups of pigs: group I (n = 6) received 1 g ethanol/kg body weight per day orally with water for 24 days, group II (n = 6) received 2 g ethanol/kg orally with water for 24 days and 4 g ethanol/kg via percutaneous intragastric catheter (PIC) for the next 24 days, group III (n = 6) received 6 g ethanol/kg via PIC for 72 days. The catheter was placed after insufflation of the stomach using an orogastric tube. PIC was successfully placed in each pig. No complications occurred during placement. The total amount of the administrated dose was assimilated each time. PIC is a safe, effective, well tolerated, and precise method of administering ethanol that is inexpensive and easy to perform. Ethanol administration via PIC is a convenient and effective mean of exposing animals to high levels of alcohol on a long-term basis.
Oleszczuk
Agnieszka
A
Department of Surgery, University of Leipzig, Germany. m.schoen@klinikumkarlsruhe.de
Spannbauer
Michael M
MM
Bluher
Matthias
M
Ott
Rudolf
R
Pietsch
Uta-Carolin
UC
Schneider
Katja
K
Madaj-Sterba
Petra
P
Furll
Manfred
M
Hauss
Johann P
JP
Schön
Michael R
MR
D000284:Administration, Oral; D000818:Animals; D002404:Catheterization / Q000295:instrumentation / Q000379:methods* / Q000662:veterinary*; D000431:Ethanol / Q000008:administration & dosage*; D013270:Stomach; D034421:Sus scrofa; D013649:Taste
D000431:Ethanol