title: Central mucoepidermoid carcinoma: report of a case with 11 years' evolution and peculiar macroscopical and clinical characteristics.
abstract: Central mucoepidermoid carcinomas (CMC) are uncommon tumours, comprising 2-3% of all mucoepidermoid carcinomas reported. They have been reported in patients of all ages, ranging from 1 to 78-years, with the overwhelming majority occurring in the 4th and 5th decades of life. They are histologically low-grade cancers, usually affecting the mandible as uniocular or multiocular radiographic lesions. The authors report a case of CMC of the mandible with a long evolution, and peculiar clinical and macroscopical features related with the long term evolution of the disease. A 53-year-old male patient had expansion of buccal and lingual cortices of the anterior region of the mandible, covered by ulcerated mucosa, with 11 years evolution. An incisional biopsy was performed, and the histopathological findings confirm low-grade mucoepidermoid carcinoma. The patient was treated with a mandibulectomy, followed by supraomohyoid neck dissection. There was no evidence of local recurrence, regional or distant metastasis revealed; and the patient was alive and without disease after a follow-up interval of 36 months.
authors.affiliation: Institute of Health Research, SP, Brazil. renata-tucci@uol.com.br
authors.forename: Renata
authors.initials: R
authors.lastname: Tucci
authors.forename: Luciana-Fasanella
authors.initials: LF
authors.lastname: Matizonkas-Antonio
authors.forename: Artur-Aburad
authors.initials: AA
authors.lastname: de Carvalhosa
authors.forename: Paulo-Henrique-de Sousa
authors.initials: PH
authors.lastname: Castro
authors.forename: Fabio-Daumas
authors.initials: FD
authors.lastname: Nunes
authors.forename: Décio-dos Santos
authors.initials: DD
authors.lastname: Pinto
mesh_terms: D018277:Carcinoma, Mucoepidermoid / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D013997:Time Factors