title: Effects of 10% carbamide peroxide treatment and sodium fluoride therapies on human enamel surface microhardness.
abstract: This study sought to evaluate the microhardness of enamel submitted to 10% carbamide peroxide treatment and different methods of remineralization involving sodium fluoride (NaF). Non-erupted third molars were used and 75 enamel blocks with standardized dimensions (4.0 x 4.0 x 2.0 mm) were obtained. Enamel blocks were randomly divided into five groups (n = 15): one control (no bleaching and no fluoride treatment), one receiving a 10% carbamide peroxide treatment, one receiving 10% carbamide peroxide plus acidulated phosphate fluoride, one receiving 10% carbamide peroxide with 0.2% NaF, and one receiving 10% carbamide peroxide and 0.05% NaF. There were no differences among four of the groups (p > 0.05); the group receiving 10% carbamide peroxide only was different from all other groups (p < 0.05). Based on these results, NaF therapies are recommended during carbamide peroxide bleaching treatments.
authors.affiliation: Department of Dentistry, University of Taubate, Brazil.
authors.forename: Guilherme Alberto Loureiro
authors.initials: GA
authors.lastname: Leandro
authors.forename: Mariana Lerner
authors.initials: ML
authors.lastname: Attia
authors.forename: Vanessa
authors.initials: V
authors.lastname: Cavalli
authors.forename: Marcos Augusto
authors.initials: MA
authors.lastname: do Rego
authors.forename: Priscila Christian Suzy
authors.initials: PC
authors.lastname: Liporoni
mesh_terms: D000077463:Carbamide Peroxide; D002327:Cariostatic Agents / Q000627:therapeutic use; D003743:Dental Enamel / Q000000981:diagnostic imaging / Q000187:drug effects; D004338:Drug Combinations; D005460:Fluorides, Topical / Q000627:therapeutic use; D006244:Hardness / Q000187:drug effects*; D006801:Humans; D010545:Peroxides / Q000009:adverse effects*; D012969:Sodium Fluoride / Q000627:therapeutic use*; D014073:Tooth Bleaching / Q000009:adverse effects*; D017001:Tooth Demineralization / Q000139:chemically induced*; D014089:Tooth Remineralization / Q000379:methods; D014463:Ultrasonography; D014508:Urea / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D002327:Cariostatic Agents; D004338:Drug Combinations; D005460:Fluorides, Topical; D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea; D012969:Sodium Fluoride