Utility of surface-supported bilayers in studies of transmembrane helix dimerization.
This review focuses on the methods that are available to study transmembrane (TM) helix dimerization in membrane-like environments (either bacterial membranes or lipid bilayers, as mimics of the eukaryotic cellular membrane), with an emphasis on the utility of surface-supported bilayers in such studies.
Li
Edwin
E
Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Merzlyakov
Mikhail
M
Lin
Janice
J
Searson
Peter
P
Hristova
Kalina
K
D000818:Animals; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D008962:Models, Theoretical; D055503:Protein Multimerization
D008051:Lipid Bilayers; D008565:Membrane Proteins