title: Synthesis of hexahelicene and 1-methoxyhexahelicene via cycloisomerization of biphenylyl-naphthalene derivatives.
abstract: The new approach provides nonphotochemical syntheses of helicenes based on the easy, convergent, and modular assembly of key biphenylyl-naphthalenes and their platinum-catalyzed double cycloisomerization. This sequence of reactions provides a synthetic route to helicenes in two steps from simply accessible building blocks. Furthermore, the method enables the introduction of substituents into the hexahelicene skeleton. The strategy developed is exemplified by the synthesis of 6,10-dimethylhexahelicene and 1-methoxy-6,10-dimethylhexahelicene.
authors.affiliation: Institute of Chemical Process Fundamentals, AS CR, Rozvojová 135, CZ-16502 Prague 6, Czech Republic. storchj@icpf.cas.cz
authors.forename: Jan
authors.initials: J
authors.lastname: Storch
authors.forename: Jan
authors.initials: J
authors.lastname: Sýkora
authors.forename: Jan
authors.initials: J
authors.lastname: Cermák
authors.forename: Jindrich
authors.initials: J
authors.lastname: Karban
authors.forename: Ivana
authors.initials: I
authors.lastname: Císarová
authors.forename: Ales
authors.initials: A
authors.lastname: Růzicka