Endoscopic therapy for Barrett's esophagus.
Recent retrospective cohort data and a prospective randomized sham controlled trial have clearly documented the impact of endoscopic ablation therapy on dysplasia and Barrett's esophagus (BE). The clinical indications for ablation of BE includes high-grade dysplasia and intramucosal adenocarcinoma. The techniques of resection of mucosal irregularities and of ablation are reviewed, primarily thermal and photodynamic ablation. Ablation of BE with neoplasia has appropriately entered the clinical arena.
Sampliner
Richard E
RE
Southern Arizona VA Health Care System, University of Arizona College of Medicine, Tucson, Arizona 85723, USA. Richard.Sampliner@va.gov
D055011:Ablation Techniques / Q000379:methods*; D001471:Barrett Esophagus / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D006801:Humans