Managing mycetomas.
Mycetomas are chronic, granulomatous, subcutaneous infections caused by traumatic inoculation into the skin of either the actinomycetes bacteria or the eumycetes fungi, giving rise to actinomycetomas and eumycetomas, respectively. They are endemic in the tropics afflicting mainly those of low socio-economic status and men working in agriculture. The disease is slowly progressive and can cause bone involvement, which can result in considerable disability. Late presentation is not uncommon making them notoriously difficult to manage. This article highlights the important aspects of their management and developments in drug therapy.
Ameen
Mahreen
M
St John's Institute of Dermatology, Guy's and St Thomas' Hospital, Westminister Bridge Road, London, SEI 7EH, UK. mahreenameen@hotmail.com
D039903:Actinobacteria / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008271:Mycetoma / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D012959:Socioeconomic Factors; D014329:Tropical Climate
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents