title: Molecular genetics of atherosclerosis.
abstract: Atherosclerosis is a complex multifocal arterial disease involving interactions of multiple genetic and environmental factors. Advances in techniques of molecular genetics have revealed that genetic polymorphisms significantly influence susceptibility to atherosclerotic vascular diseases. A large number of candidate genes, genetic polymorphisms and susceptibility loci associated with atherosclerotic diseases have been identified in recent years and their number is rapidly increasing. In this review we focus on some of the major candidate genes and genetic polymorphisms associated with human atherosclerotic vascular diseases.
authors.affiliation: Department of Molecular Medicine and Biotechnology, A.I. Virtanen Institute, University of Kuopio, Kuopio, Finland. himadri.roy@uku.fi
authors.forename: Himadri
authors.initials: H
authors.lastname: Roy
authors.forename: Shalini
authors.initials: S
authors.lastname: Bhardwaj
authors.forename: Seppo
authors.initials: S
authors.lastname: Yla-Herttuala
mesh_terms: D050197:Atherosclerosis / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D007249:Inflammation / Q000235:genetics; D050356:Lipid Metabolism / Q000235:genetics; D018384:Oxidative Stress / Q000235:genetics; D011110:Polymorphism, Genetic