Impact of discrepancies between the Abbott realtime and cobas TaqMan assays for quantification of human immunodeficiency virus type 1 group M non-B subtypes.
Viral loads in 249 clinical samples from individual patients infected with human immunodeficiency virus type 1 non-B subtypes were determined with both the Abbott RealTime and Cobas TaqMan assays. The differences exceeded 0.5 log for about 20% of samples and 1 log for 3%, with higher values always from the Abbott assay in the latter cases.
Wirden
M
M
Department of Virology, Pitié-Salpêtriere Hospital, Paris, France. marc.wirden@psl.aphp.fr
Tubiana
R
R
Marguet
F
F
Leroy
I
I
Simon
A
A
Bonmarchand
M
M
Ait-Arkoub
Z
Z
Murphy
R
R
Marcelin
A G
AG
Katlama
C
C
Calvez
V
V
D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D019562:Viral Load / Q000379:methods*
D011933:Reagent Kits, Diagnostic