[Detection of intraplaque hemorrhage with use of screening black-blood MRI].
The evaluation of plaque characteritics as well as the degree of luminal narrowing is important in the management of carotid stenosis. Several reports have shown that intraplaque hemorrhage (IPH), which plays a pivotal role in plaque vulnerability, emits high signal intensity on T1-weighted images of high-resolution black-blood (BB) MRIs. When an MRI is used to screen for vulnerable plaque, a short scanning duration and a simple MRI protocol are required. This study assessed the utility of screening BB-MRI to detect IPH. Ninety-three consecutive cases with atherosclerotic carotid stenosis scheduled for carotid endarterectomy (CEA) or carotid artery stenting between January 2005 and December 2007 were included. High-resolution BB-MRI scans were obtained with 2D double-inversion recovery fast spin-echo sequences with cardiac gating. Screening BB-MRIs were performed with 3D gradient-echo sequences suppressing blood flow signals by radiofrequency wave spatial saturation over the scanning field of 3D time-of-flight MRA. The relative overall plaque signal intensities with reference to the sternocleidomastoid muscle were calculated, and the correlation of intensities on T1-weighted images between high-resolution BB-MRI and screening BB-MRI was investigated. We excluded 50 cases because of restenosis following CEA, use of a pacemaker, a long interval (>10 days) between high-resolution and screening BB-MRI examinations, or poor-quality images. Among the 43 cases included, the relative overall plaque signal intensity of high-resolution BB-MRI and screening BB-MRI were closely correlated (r = 0.568, p < 0.001). Screening BB-MRI can be an alternative to high-resolution BB-MRI in the assessment of IPH and may be a useful tool for detection of vulnerable plaque.
Endo
Hideki
H
Department of Neurosurgery, Kurashiki Central Hospital, Japan.
Yoshida
Kazumichi
K
Kurosaki
Yoshitaka
Y
Sadamasa
Nobutake
N
Narumi
Osamu
O
Chin
Masaki
M
Yamagata
Sen
S
D000368:Aged; D016893:Carotid Stenosis / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male