[Multivariate analysis of risk factors of lymph node metastasis in early gastric cancer].
OBJECTIVE
To investigate the clinicopathological factors affecting lymph node metastasis in early gastric cancer(EGC).


METHODS
Clinicopathological data of 369 patients with EGC from Jan. 1999 to Jun. 2008 were analyzed retrospectively. Multivariate analysis was performed to find the risk factors affecting lymph node metastasis.


RESULTS
The age, gender, tumor size, invasion depth, histological classification and vascular cancer thrombosis were associated with lymph node metastasis. Multivariate analysis showed that tumor size and depth of invasion were main independent risk factors.


CONCLUSIONS
The main independent risk factors affecting lymph node metastasis in EGC are tumor size and invasion depth. The gender, vascular cancer thrombosis, tumor size, invasion depth and histological classification should be considered to establish the surgical program.
Fang
Yi
Y
Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
Zhao
Dong-bing
DB
Zhou
Jian-guo
JG
Cai
Jian-qiang
JQ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D016015:Logistic Models; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000473:pathology*