title: Blood flow restricted exercise and skeletal muscle health.
abstract: For nearly half a century, high mechanical loading and mechanotransduction pathways have guided exercise recommendations for inducing muscle hypertrophy. However, emerging research on low-intensity exercise with blood flow restriction challenges this paradigm. This article will describe the BFR exercise model and discuss its efficacy, potential mechanisms, and clinical viability.
authors.affiliation: Department of Aging and Geriatric Research, Institute on Aging, University of Florida, Gainesville, FL, USA.
authors.forename: Todd M
authors.initials: TM
authors.lastname: Manini
authors.forename: Brian C
authors.initials: BC
authors.lastname: Clark
mesh_terms: D000222:Adaptation, Physiological; D004576:Electromyography; D015444:Exercise; D006801:Humans; D006984:Hypertrophy / Q000209:etiology*; D007511:Ischemia / Q000150:complications*; D008962:Models, Theoretical; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000502:physiology; D013314:Stress, Mechanical