title: Impact of discrepancies between the Abbott realtime and cobas TaqMan assays for quantification of human immunodeficiency virus type 1 group M non-B subtypes.
abstract: Viral loads in 249 clinical samples from individual patients infected with human immunodeficiency virus type 1 non-B subtypes were determined with both the Abbott RealTime and Cobas TaqMan assays. The differences exceeded 0.5 log for about 20% of samples and 1 log for 3%, with higher values always from the Abbott assay in the latter cases.
authors.affiliation: Department of Virology, Pitié-Salpêtriere Hospital, Paris, France. marc.wirden@psl.aphp.fr
authors.forename: M
authors.initials: M
authors.lastname: Wirden
authors.forename: R
authors.initials: R
authors.lastname: Tubiana
authors.forename: F
authors.initials: F
authors.lastname: Marguet
authors.forename: I
authors.initials: I
authors.lastname: Leroy
authors.forename: A
authors.initials: A
authors.lastname: Simon
authors.forename: M
authors.initials: M
authors.lastname: Bonmarchand
authors.forename: Z
authors.initials: Z
authors.lastname: Ait-Arkoub
authors.forename: R
authors.initials: R
authors.lastname: Murphy
authors.forename: A G
authors.initials: AG
authors.lastname: Marcelin
authors.forename: C
authors.initials: C
authors.lastname: Katlama
authors.forename: V
authors.initials: V
authors.lastname: Calvez
mesh_terms: D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D019562:Viral Load / Q000379:methods*
chemical_list: D011933:Reagent Kits, Diagnostic