title: Collagen mechanics: a rationale for radiofrequency energy to treat mitral regurgitaton.
abstract: Despite a variety of pharmacological interventions to limit the regurgitant fraction, mitral regurgitation requires surgical intervention for definitive treatment. New nonsurgical techniques are being applied to treat mitral regurgitation. The mitral and tricuspid annuli are areas of dense collagen. Application of heat, in the form of radiofrequency energy, can be used to shrink mitral valve annuli and offers a promising approach to the treatment of mitral regurgitation.
authors.affiliation: Banner Estrella Medical Center, Phoenix, Arizona, USA.
authors.forename: Shishir
authors.initials: S
authors.lastname: Murarka
authors.forename: Thomas
authors.initials: T
authors.lastname: Witzel
authors.forename: Duane
authors.initials: D
authors.lastname: Dickens
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Takeda
authors.forename: Richard R
authors.initials: RR
authors.lastname: Heuser
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D000818:Animals; D017115:Catheter Ablation; D003094:Collagen / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008944:Mitral Valve Insufficiency / Q000628:therapy*; D012756:Sheep; D013552:Swine
chemical_list: D003094:Collagen