title: Brain abscess caused by Tsukamurella tyrosinosolvens in an immunocompetent patient.
abstract: We describe a previously healthy patient with chronic otitis media complicated with cerebellar abscess caused by Tsukamurella tyrosinosolvens. The organism was identified based on conventional biochemical identification methods, PCR-restriction fragment length polymorphism analysis of the hsp65 gene, and 16S rRNA gene sequencing. The patient was treated successfully with debridements and prolonged antibiotic therapy.
authors.affiliation: Department of Internal Medicine, Far-East Memorial Hospital, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Wang-Huei
authors.initials: WH
authors.lastname: Sheng
authors.forename: Yu-Tsung
authors.initials: YT
authors.lastname: Huang
authors.forename: Shan-Chwen
authors.initials: SC
authors.lastname: Chang
authors.forename: Po-Ren
authors.initials: PR
authors.lastname: Hsueh
mesh_terms: D000192:Actinomycetales / Q000302:isolation & purification*; D000193:Actinomycetales Infections / Q000175:diagnosis* / Q000382:microbiology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D001922:Brain Abscess / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D005260:Female; D006360:Heat-Shock Proteins / Q000235:genetics; D006801:Humans; D010033:Otitis Media / Q000150:complications; D012150:Polymorphism, Restriction Fragment Length; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D006360:Heat-Shock Proteins; D012336:RNA, Ribosomal, 16S