title: Hepatocellular adenoma in a male with familial adenomatous polyposis coli.
abstract: Hepatocellular adenoma (HA) is a benign liver tumor most frequently occurring in young women using oral contraceptives. We report a rare case of HA in a 27-year-old male patient with familial adenomatous polyposis (FAP). The patient underwent a total colectomy and ileo-rectal anastomosis for FAP in 2003. A preoperative computed tomography scan of the abdomen disclosed a tumor in the left-lobe of the liver, 5.8 cm in diameter. Pathologic examination of a needle biopsy disclosed HA, but he had never used anabolic steroids or other known inducers of HA. The size of the liver mass gradually increased to 8.5 cm during a follow-up period of 38 months, and a left hepatectomy was performed in 2006. Pathology of the resected specimen confirmed the diagnosis of HA. Although FAP is known to be complicated with neoplasia in various extracolonic organs, only five reported cases of HA have developed in patients with FAP, including this case. This is the first report of HA to develop in a male FAP patient.
authors.affiliation: Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center Hospital, 1007 Shimo-Nagakubo, Sunto-Nagaizumi, Shizuoka, 411-8777, Japan. yukiyasu@tj9.so-net.ne.jp
authors.forename: Yukiyasu
authors.initials: Y
authors.lastname: Okamura
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Maeda
authors.forename: Kazuya
authors.initials: K
authors.lastname: Matsunaga
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kanemoto
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Keiko
authors.initials: K
authors.lastname: Sasaki
authors.forename: Shigeki
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Uesaka
mesh_terms: D000236:Adenoma / Q000453:epidemiology* / Q000601:surgery; D011125:Adenomatous Polyposis Coli / Q000453:epidemiology* / Q000601:surgery; D000328:Adult; D003082:Colectomy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000601:surgery; D008297:Male; D016609:Neoplasms, Second Primary / Q000453:epidemiology*