[Observe the curative effect of n-Butyl cyanoacrylate injection in treating laryngopharynx hemangioma].
OBJECTIVE
To evaluate the clinical effectiveness of injection n-Butyl cyanoacrylate (NBCA) in treating laryngopharynx hemangioma.


METHODS
Thirty cases of laryngopharynx hemangioma who received NBCA injection were obtained from our department 1998-2007. Twenty-five cases had tracheotomy under General anesthesia, and NBCA was injected into hemangioma by direct laryngoscopy. NBCA was mixed with iodide, and the concentration was 25.00% to 33.33%, NBCA dosage was 0.5 ml to 2.0 ml. There were 5 cases whose hemangioma confined to oropharynx didn't have tracheotomy, and they were injected straightly with the speculum oris. We observed the shedding of hemangioma in different time.


RESULTS
Hemangioma with diameter less than 1 cm, shedded in about 1 month. However, hemangioma with diameter more than 4 cm, shedded in a period more than 3.5 month. No recurrence was observed in the follow up of 3 months to seven years.


CONCLUSIONS
Avoiding dissection of neck and repetitious operation, NBCA injection could be a safe, simple and effective therapy for laryngopharynx hemangioma.
Li
Weimin
W
Department of Otolaryngology-Head and Neck Surgery, General Hospital of PLA, Beijing, 100853, China. Liweimin301@163.com
Feng
Bo
B
Wang
Jialing
J
Wu
Wenming
W
Liu
Liangfa
L
Wang
Rongguang
R
Huang
Dongyan
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004621:Embolization, Therapeutic; D004659:Enbucrilate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
D004659:Enbucrilate