Crossed-aldol condensation of cycloalkanones with aromatic aldehydes catalyzed by copper(II) trifluoroacetate.
A simple and solvent-free procedure to synthesize alpha,alpha'-bis(substituted benzylidene) cycloalkanones, catalyzed by copper(II) trifluoroacetate through crossed-aldol condensation of various aromatic aldehydes with cyclic ketones is reported. The reaction proceeded smoothly in good to excellent yields.
Song
Dailei
D
Department of Chemistry, School of Chemistry and Materials Science, Liaoning Shihua University, P. R. China.
Chen
Yongli
Y
Wang
Runxia
R
Liu
Chunsheng
C
Jiang
Heng
H
Luo
Genxiang
G
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014269:Trifluoroacetic Acid / Q000737:chemistry*
D000447:Aldehydes; D007659:Ketones; D009942:Organometallic Compounds; D003300:Copper; D014269:Trifluoroacetic Acid