title: Recoil effect on beta-decaying in vivo generators, interpreted for (103)Pd/(103m)Rh.
abstract: The use of Auger emitters as potential radiopharmaceuticals is being increasingly investigated. One of the radionuclides of interest is (103m)Rh, which can be produced from (103)Ru or (103)Pd in an in vivo generator. A potential problem, however, is the recoil of the (103m)Rh out of the carrier molecule and even out of the target cell. In order to determine the likelihood of this happening in the (103)Pd/(103m)Rh, case calculations were made to prove that this does not happen. The equations were generalised for all radionuclides with an atomic mass of 10-240 as a tool for determining the recoil threshold of any beta-emitting radionuclide.
authors.affiliation: Radiochemistry, Necsa (South African Nuclear Energy Corporation Ltd.), PO Box 582, Pretoria 0001, South Africa.
authors.forename: Zoltan
authors.initials: Z
authors.lastname: Szucs
authors.forename: Johann
authors.initials: J
authors.lastname: van Rooyen
authors.forename: Jan Rijn
authors.initials: JR
authors.lastname: Zeevaart
mesh_terms: D001918:Brachytherapy / Q000592:standards*; D010165:Palladium; D011868:Radioisotopes / Q000008:administration & dosage / Q000302:isolation & purification*; D011876:Radionuclide Generators / Q000592:standards*; D019275:Radiopharmaceuticals; D012238:Rhodium / Q000008:administration & dosage / Q000302:isolation & purification*
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals; D010165:Palladium; D012238:Rhodium