title: Comparison of retinal degeneration in the normal goldfish and the megalophthalmic black moor goldfish after optic nerve transection and lens extraction.
abstract: A comparison in retinal degeneration was studied in the normal goldfish and the megalophthalmic goldfish after optic nerve transection or lens extraction by the TUNEL (Terminal transferase-mediated dUTP nick end labeling) technique. A significant number of TUNEL positive cells appeared in both cases 7 days after injury, with a more prominent result in the megalophthalmic eye. Lens extraction, had less apoptotic cell death in the experimental retinas.
authors.affiliation: Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Ying
authors.forename: Maria S M
authors.initials: MS
authors.lastname: Wai
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.forename: Jeanie P C
authors.initials: JP
authors.lastname: Lau
authors.forename: Elizabeth Lucy
authors.initials: EL
authors.lastname: Forster
authors.forename: David T
authors.initials: DT
authors.lastname: Yew
mesh_terms: D000818:Animals; D017209:Apoptosis; D006054:Goldfish; D020287:In Situ Nick-End Labeling; D007908:Lens, Crystalline / Q000601:surgery*; D020221:Optic Nerve Injuries / Q000473:pathology*; D012160:Retina / Q000473:pathology*; D012162:Retinal Degeneration / Q000473:pathology*