title: Two cases of hemichorea-hemiballism with nonketotic hyperglycemia: a new point of view.
abstract: Hemichorea-hemiballism (HCHB) is an usually continuous, nonpatterned, involuntary movement disorder caused by basal ganglia dysfunction, commonly due to a vascular lesion, described in nonketotic hyperglycemic patients. Particular computed tomography and magnetic resonance imaging findings have been described. The pathogenic mechanism of chorea arising during hyperglycemia and the nature of neuroimaging findings are unclear. In this paper we describe two elderly women with onset of HCHB during a hyperglycemic episode. The symptoms persisted in one of them after recovery of normal glycemia. The pathophysiological mechanism of the disease is discussed in the light of clinical and neuroradiological follow-up.
authors.affiliation: Operative Unit of Neurology and Neurometabolic Diseases, Policlinico "Le Scotte", University of Siena, V.le Bracci, 2, 53100, Siena, Italy. Battisti@unisi.it
authors.forename: Carla
authors.initials: C
authors.lastname: Battisti
authors.forename: Francesca
authors.initials: F
authors.lastname: Forte
authors.forename: Elisa
authors.initials: E
authors.lastname: Rubenni
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Dotti
authors.forename: Anna
authors.initials: A
authors.lastname: Bartali
authors.forename: Paola
authors.initials: P
authors.lastname: Gennari
authors.forename: Antonio
authors.initials: A
authors.lastname: Federico
authors.forename: Alfonso
authors.initials: A
authors.lastname: Cerase
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001480:Basal Ganglia Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002819:Chorea / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D020820:Dyskinesias / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D020158:Hyperglycinemia, Nonketotic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed