Signaling aversive events in the midbrain: worse than expected.
Although we know a great deal about how the brain processes information about aversive and appetitive stimuli, it is not clear how these two systems interact to guide behavior. In this issue of Neuron, Jhou and colleagues identify a region in the midbrain tegmentum that signals aversive events and inhibits midbrain dopamine neurons.
Quirk
Gregory J
GJ
Departments of Psychiatry and Anatomy and Neurobiology, University of Puerto Rico School of Medicine, San Juan, PR 00936.
Sotres-Bayon
Francisco
F
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology; D008636:Mesencephalon / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*