[A case report--complete disappearance of multiple intrahepatic recurrences and portal thrombus in a case of hepatocellular carcinoma treated with UFT-E].
Here, we present a case of recurrent hepatocellular carcinoma(HCC)with portal thrombus that disappeared within only two months by oral tegafur(UFT-E). A 82-year-old man had recurrent multiple HCCs, which caused liver dysfunction because of diminished portal flow by the portal thrombus. Hepatic arterial chemo-embolization and continuous arterial CDDP-infusion chemotherapy did not show any efficacy. Next, oral UFT-E administration(low-dose, 300 mg/day)was begun, and after 1 month, PIVKA-II decreased and liver dysfunction was normalized. His complete response continued for 8 months until his death due to aspiration pneumonia and progressive dementia. Low-dose UFT-E administration may be considered a candidate in a case of HCC with no alternative treatment.
Hayashi
Hiroshi
H
Dept. of Surgery, Arita Kyoritsu Hospital.
Anegawa
Go
G
Sonoda
Hideto
H
Inoue
Fumio
F
D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000098:blood supply* / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D008297:Male; D012008:Recurrence; D005641:Tegafur / Q000627:therapeutic use; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014498:Uracil / Q000627:therapeutic use
D005641:Tegafur; D014498:Uracil