title: A convenient synthesis of p-substituted 1-arylsulfonyl-pyrrolidin-2-ones.
abstract: A convenient and novel method of cyclisation of 4-(4-substituted-phenylsulfonamido)-butanoic acids to their corresponding p-substituted 1-arylsulfonyl-pyrrolidin-2-ones was achieved by using polyphosphate ester (PPE). The reaction times were considerably reduced, with an increase in yields, when PPE was used in combination with a catalytic amount of pyridine.
authors.affiliation: Department of Chemistry, University of Gujrat, Gujrat, Pakistan. mzareef71@yahoo.com
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zareef
authors.forename: Rashid
authors.initials: R
authors.lastname: Iqbal
authors.forename: Khalid M
authors.initials: KM
authors.lastname: Khan
authors.forename: Javid H
authors.initials: JH
authors.lastname: Zaidi
authors.lastname: Zia-Ullah
authors.forename: Muhammad
authors.initials: M
authors.lastname: Arfan
mesh_terms: D015394:Molecular Structure; D011122:Polyphosphates / Q000737:chemistry; D011760:Pyrrolidinones / Q000138:chemical synthesis*
chemical_list: D011122:Polyphosphates; D011760:Pyrrolidinones