title: Selective adsorption of DNA on chiral surfaces: supercoiled or relaxed conformation.
abstract: The right fit: Plasmid DNA molecules show chirality-dependent interaction with gold surfaces modified by L and D N-isobutyrylcysteine. Relaxed DNA molecules have a stronger interaction and adsorption on the L surface, while their counterparts on the D surface maintain a supercoiled conformation, indicating a weak interaction (see picture).
authors.affiliation: Physikalisches Institut, WWU Münster, Wilhelm-Klemm-Strasse 10, 48149 Müster, Germany.
authors.forename: Hui
authors.initials: H
authors.lastname: Gan
authors.forename: Kangjian
authors.initials: K
authors.lastname: Tang
authors.forename: Taolei
authors.initials: T
authors.lastname: Sun
authors.forename: Michael
authors.initials: M
authors.lastname: Hirtz
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Lifeng
authors.initials: L
authors.lastname: Chi
authors.forename: Stefan
authors.initials: S
authors.lastname: Butz
authors.forename: Harald
authors.initials: H
authors.lastname: Fuchs
mesh_terms: D000327:Adsorption; D003198:Computer Simulation; D003545:Cysteine / Q000031:analogs & derivatives* / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009690:Nucleic Acid Conformation; D010957:Plasmids / Q000737:chemistry*; D013237:Stereoisomerism; D013499:Surface Properties
chemical_list: C096972:N-isobutyrylcysteine; D006046:Gold; D004247:DNA; D003545:Cysteine