Segmented biopolyurethanes for medical applications.
Polyurethanes are one of the most popular groups of biomaterials applied for medical devices. Their segmented block copolymeric character endows them a wide range of versatility in terms of tailoring their physical properties, blood and tissue compatibility. Polyester- and polyether-urethanes have been modified with hydroxypropyl cellulose aiming the change of their surface and bulk characteristics to confer them biomaterial qualities. In this respect, dynamic contact angle measurements, dynamic mechanical analyses accompanied by mechanical testing have been done. Platelet adhesion test has been carried out in vitro and the use of hydroxypropyl cellulose in the polyurethane matrix reduces the platelet adhesion and therefore recommends them as candidates for biocompatible materials.
Macocinschi
Doina
D
Petru Poni Institute of Macromolecular Chemistry, Iasi, Romania. eradro2002@yahoo.com
Filip
Daniela
D
Vlad
Stelian
S
Cristea
Mariana
M
Butnaru
Maria
M
D001672:Biocompatible Materials / Q000737:chemistry / Q000627:therapeutic use; D001696:Biomechanical Phenomena; D006801:Humans; D008422:Materials Testing; D010973:Platelet Adhesiveness / Q000502:physiology; D011140:Polyurethanes / Q000737:chemistry / Q000627:therapeutic use*; D013314:Stress, Mechanical; D013499:Surface Properties; D013696:Temperature
D001672:Biocompatible Materials; D011140:Polyurethanes; C115016:polyetherurethane