Repeat magnetoencephalography and surgeries to eliminate atonic seizures of non-lesional frontal lobe epilepsy.
A 7-year-old boy presented with intractable head nodding and atonic seizures since the age of 3 years and severe behavior problems unsuitable for video EEG monitoring. We performed magnetoencephalography (MEG) 4 times: before (1) corpus callosotomy, (2) left frontal cortical resection with multiple subpial transection and (3) resection of residual MEG spike sources, which eliminated seizures. Repeat MEGs consistently localized the epileptogenic zone in a patient with intractable residual non-lesional left frontal lobe epilepsy.
Nakayama
Tojo
T
Department of Child Neurology, National Center Hospital of Neurology and Psychiatry, 4-1-1 Ogawa-higashi-machi, Kodaira, Tokyo 187-8553, Japan. tojo-nakayama@umin.ac.jp
Otsuki
Taisuke
T
Kaneko
Yu
Y
Nakama
Hideyuki
H
Kaido
Takanobu
T
Otsubo
Hiroshi
H
Nakagawa
Eiji
E
Sasaki
Masayuki
M
Sugai
Kenji
K
D002648:Child; D003337:Corpus Callosum / Q000000981:diagnostic imaging / Q000601:surgery; D004569:Electroencephalography / Q000379:methods; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D015225:Magnetoencephalography; D008297:Male; D050812:Split-Brain Procedure / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods