Diastereoselective synthesis of fused [1,3]thiazolo[1,3]oxazins and [1,3]oxazino[2,3-b][1,3]benzothiazoles.
An efficient diastereoselective synthesis of 7-ethyl 5,6-dialkyl 7H-[1,3]thiazolo[2,3-b][1,3]oxazin-5,6, 7-tricarboxylates and 2-ethyl 3,4-dialkyl 2H-[1,3]oxazino [2,3-b][1,3]benzothiazole-2,3,4-tricarboxylates via reaction of thiazole and benzothiazole with dialkyl acetylenedicarboxylates in the presence of ethyl pyruvate is described.
Yavari
Issa
I
Chemistry Department, Tarbiat Modares University, Tehran, Iran. yavarisa@modares.ac.ir
Hossaini
Zinatossadat
Z
Souri
Sanaz
S
Seyfi
Samereh
S
D052160:Benzothiazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D052160:Benzothiazoles; D002264:Carboxylic Acids; D010078:Oxazines