title: Muscle rupture caused by exacerbated spasticity in a patient with multiple sclerosis.
abstract: We report a case of muscle rupture caused by acute exacerbation of spasticity in a patient with primary chronic progressive multiple sclerosis (PPMS). A complete disruption of the adductor muscles was diagnosed by sonography and still reproducible in a follow-up three months after the clinical event. To our knowledge, this is the first case report of muscle rupture caused by spasticity in a patient with MS. In addition to the clinical case report we give a short overview of morphological and functional changes in spastic muscle and current standards of symptomatic therapy.
authors.affiliation: Department of Neurology, University of Rostock, Gehlsheimer Str. 20, 18147 Rostock, Germany. robert.patejdl@uni-rostock.de
authors.forename: Robert
authors.initials: R
authors.lastname: Patejdl
authors.forename: Alexander
authors.initials: A
authors.lastname: Winkelmann
authors.forename: Reiner
authors.initials: R
authors.lastname: Benecke
authors.forename: Uwe Klaus
authors.initials: UK
authors.lastname: Zettl
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D009128:Muscle Spasticity / Q000209:etiology*; D018482:Muscle, Skeletal / Q000293:injuries*; D012421:Rupture / Q000473:pathology