title: Lower urinary tract symptoms and sexual health: the role of gender, lifestyle and medical comorbidities.
abstract: OBJECTIVE
  To investigate the association between urological symptoms and self-reported measures of sexual activity, desire and function in large representative samples of men and women in the Boston Area Community Health (BACH) survey.
  
  
  METHODS
  The BACH survey is a racially and ethnically diverse random sample of 5503 community-dwelling residents aged 30-79 years, of Boston, MA, USA. Urological symptoms and sexual function were assessed in men and women at baseline using validated self-report measures, i.e. the International Prostate Symptom Score (IPSS), International Index of Erectile Function, and Female Sexual Function Index. Bivariate and multivariate analyses were conducted to assess the degree of association of sexual function measures with LUTS and other common urological problems in men and women in the BACH sample, controlling for the effects of age, medical comorbidities, and lifestyle factors.
  
  
  RESULTS
  Urological symptoms were associated with a significant decrease in sexual activity and function in both men and women. Women were more likely to report low sexual desire than men. Low sexual desire was associated with depression, nocturia and prostatitis in men. Erectile dysfunction in men was significantly associated with LUTS, nocturia and prostatitis in bivariate associations, and with prostatitis in multivariate analyses, controlling for the effects of diabetes and other comorbidities. In the multivariate analysis in women, sexual dysfunction was primarily associated with depression and inversely with alcohol use.
  
  
  CONCLUSIONS
  Sexual activity and function were diminished in both men and women with urological symptoms, although women reported more sexual problems overall than men, and the profile of risk factors and comorbidities was different across genders.
authors.affiliation: New England Research Institutes, Inc., Watertown, MA 02472, USA. rrosen@neriscience.com
authors.forename: Raymond C
authors.initials: RC
authors.lastname: Rosen
authors.forename: Carol L
authors.initials: CL
authors.lastname: Link
authors.forename: Michael P
authors.initials: MP
authors.lastname: O'Leary
authors.forename: Francois
authors.initials: F
authors.lastname: Giuliano
authors.forename: Lalitha P
authors.initials: LP
authors.lastname: Aiyer
authors.forename: Patrick
authors.initials: P
authors.lastname: Mollon
mesh_terms: D000328:Adult; D000368:Aged; D001900:Boston / Q000453:epidemiology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology / Q000209:etiology*; D014555:Urination Disorders / Q000453:epidemiology / Q000209:etiology*