title: Sonographic study of the decidua basalis in the first trimester of pregnancy.
abstract: OBJECTIVE
  To describe the sonographic appearance of the decidua basalis and its changes in the first trimester of pregnancy.
  
  
  METHODS
  We reviewed images from 159 first-trimester ultrasound examinations in 105 women with uncomplicated pregnancies who later delivered at term. The appearance of the decidua basalis layer and the sonographic changes that it underwent, including in echogenicity and thickness, were analyzed with respect to gestational age.
  
  
  RESULTS
  A distinct decidual layer could be identified consistently at 5-6 weeks' gestation and its thickness peaked at 6-7 weeks. It was seen inconsistently at 8-9 weeks and was not identifiable by 10 weeks. Its appearance changed over time, from a uniformly echogenic layer at 5-6 weeks to a heterogeneous echogenic layer at 7 weeks, corresponding to the histological evidence of trophoblast penetration. The layer then became less echogenic with time until it became unidentifiable.
  
  
  CONCLUSIONS
  There is a window of opportunity in the first trimester for sonographic examination of the decidua. This may allow screening, at an early stage, for conditions that affect the decidua during pregnancy.
authors.affiliation: Australian Women's Ultrasound Centre, Brisbane, Queensland, Australia. hsoowong@netvigator.com
authors.forename: H S
authors.initials: HS
authors.lastname: Wong
authors.forename: Y K
authors.initials: YK
authors.lastname: Cheung
authors.forename: J
authors.initials: J
authors.lastname: Tait
mesh_terms: D000293:Adolescent; D000328:Adult; D003656:Decidua / Q000000981:diagnostic imaging* / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D014327:Trophoblasts / Q000000981:diagnostic imaging* / Q000502:physiology; D016216:Ultrasonography, Prenatal; D055815:Young Adult