Comparison of different methods for detecting methicillin resistance in MRSA isolates belonging to international lineages commonly isolated in the American continent.
The aim of the present paper was to compare different methods for detecting methicillin resistance in Staphylococcus aureus. Among the isolates analyzed, 52 belonged to MRSA international lineages commonly detected in the American continent and 14 to sporadic MRSA clones. Both 30 microg-cefoxitin disk and PBP2a had 100% sensibility/specificity when the low-level heterogeneous isolates were tested and, thus, are highly recommended.
Silva-Carvalho
Maria Cícera
MC
Federal University of Rio de Janeiro, Institute of Microbiology Professor Paulo de Góes, Center for Health Science, University City, Rio de Janeiro, Brazil.
Teixeira
Lenise Arneiro
LA
Ferreira
Fabienne Antunes
FA
Ribeiro
Apoena
A
Ferreira-Carvalho
Bernadete Teixeira
BT
Figueiredo
Agnes Marie Sá
AM
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D002440:Cefoxitin / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests / Q000379:methods*; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance / Q000235:genetics*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D009656:North America; D010068:Oxacillin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D013020:South America
D000900:Anti-Bacterial Agents; D002440:Cefoxitin; D008712:Methicillin; D010068:Oxacillin