title: Case of creeping disease treated with ivermectin.
abstract: We report a case of creeping disease treated successfully with ivermectin. A 46-year-old man presented with a 1-month history of pruriginous linear erythema on his right thigh after a visit to Indonesia. Although he had no history of eating raw fish or meat, he walked along the river and in the jungle without wearing shoes. Creeping disease caused by animal hookworm was strongly suspected. The presence of parasite larvae was not confirmed in biopsied skin specimens. In enzyme-linked immunosorbent assay, serum samples were negative for binding to hookworm antigens, including Ancylostoma canium, Necator americanus and Gnathostoma doloresi. He was treated with a single 12 mg oral dose (200 microg/kg) of ivermectin. The eruption and pruritus resolved within a few days after the administration and did not relapse.
authors.affiliation: Department of Dermatology, Yokkaichi Municipal Hospital, Mie, Japan. senba-y@clin.medic.mie-u.ac.jp
authors.forename: Yuko
authors.initials: Y
authors.lastname: Senba
authors.forename: Kenshiro
authors.initials: K
authors.lastname: Tsuda
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Maruyama
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kurokawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Mizutani
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Taniguchi
mesh_terms: D000977:Antiparasitic Agents / Q000627:therapeutic use*; D006725:Hookworm Infections / Q000178:diet therapy; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use*; D007815:Larva Migrans / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin