title: Indium-catalyzed C-S cross-coupling of aryl halides with thiols.
abstract: Indium-catalyzed C-S cross-coupling of aromatic and alkane thiols with aryl halides proceeds smoothly in the presence of In(OTf)(3) (10 mol %), TMEDA (20 mol %), and KOH as a base in DMSO at 135 degrees C. When this protocol was utilized, a variety of thiols could be cross-coupled with aryl halides to afford the corresponding aryl sulfides in good to excellent yields.
authors.affiliation: Organic Chemistry Division I, Indian Institute of Chemical Technology, Hyderabad 500 007, India.
authors.forename: V Prakash
authors.initials: VP
authors.lastname: Reddy
authors.forename: K
authors.initials: K
authors.lastname: Swapna
authors.forename: A Vijay
authors.initials: AV
authors.lastname: Kumar
authors.forename: K Rama
authors.initials: KR
authors.lastname: Rao
mesh_terms: D000473:Alkanes / Q000737:chemistry; D017554:Carbon Compounds, Inorganic / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis* / Q000737:chemistry; D007204:Indium / Q000737:chemistry*; D007462:Iodobenzenes / Q000138:chemical synthesis / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000473:Alkanes; D017554:Carbon Compounds, Inorganic; D003432:Cross-Linking Reagents; D006846:Hydrocarbons, Halogenated; D007462:Iodobenzenes; D008698:Mesylates; D013438:Sulfhydryl Compounds; D013440:Sulfides; D007204:Indium; C092035:carbon sulfide; C031905:iodobenzene; C012077:trifluoromethanesulfonic acid