[Risk factors of intra-abdominal infection following gastrectomy in gastric cancer patients].
OBJECTIVE
To investigate the main risk factors associated with intra-abdominal infection(IAI) following gastrectomy in gastric cancer patients.


METHODS
Case-control study was used to investigate the clinical data of 1728 gastric carcinoma cases retrospectively by Logistic regressive analysis.


RESULTS
Univariate Logistic regressive analysis showed 16 factors, including age, malnutrition, chronic obstructive pulmonary disease(COPD), diabetes mellitus(DM), heart diseases, prothrombin time, lymphocyte count, tumor size, ascites, invasion to the adjacent organ, neoplasm TNM staging (UICC, 1997), methods of gastrectomy, blood loss, operative time, blood transfusion and extent of lymph nodal dissection,were associated with postoperative intra-abdominal infection. Binary Logistic regression analysis found that extent of lymph nodal dissection(N(2)(+) approximately N(3) and N(2)), invasion to the adjacent organ, DM, operative time, age and lymphocyte count were the independent risk factors associated with mortality.


CONCLUSIONS
Necessary interventions should be carried out to prevent IAI referring to above risk factors.
Chen
Shi-yuan
SY
Department of General Surgery, The Affiliated Hospital, Qingdao University School of Medicine, Qingdao 256603,China.
Zhou
Yan-bing
YB
Wang
Hao
H
Li
Shi-kuan
SK
Mao
Wei-zheng
WZ
Wang
Hai-bo
HB
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D006801:Humans; D016015:Logistic Models; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000209:etiology*; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D013530:Surgical Wound Infection / Q000209:etiology*; D055815:Young Adult