[Chemical constituents from dried sorophore of cultured Cordyceps militaris].
OBJECTIVE
To investigate the chemical constituents of the dried sorophore of cultured Cordyceps militaris.


METHODS
Compounds were isolated and purified by macroporous adsorption resin and silica gel column chromatography. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data (IR, FAB-MS, 1H-NMR and 13C-NMR).


RESULTS
Nine compounds were isolated and identified as: ergosta-4, 6, 8 (14)-tetraen-3-one (1), citrostadienol (2), tetracosanoic acid 2, 3-dihydroxypropyl ester (3), ergosterol (4), ergosterol peroxide (5), ergosta-7, 22-dien-3beta, 5alpha, 6beta-triol (6), cordycepin (7), adenosine (8), N-(2-hydroxyethyl) adenosine (9), respectively.


CONCLUSIONS
Compounds 1-3, 6, 9 were separated from the sorophore of cultured C. militaris for the first time.
Lv
Zi-Ming
ZM
Bejing Yiling Pharmaceutical Research and Development Center, Beijing 102600, China.
Jiang
Yong-Tao
YT
Wu
Li-Jun
LJ
Liu
Ke
K
D032661:Cordyceps / Q000737:chemistry*; D046508:Culture Techniques; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*