title: [Case report of intrathecal baclofen administration in a child with severe spasticity attributable to traumatic brain injury].
abstract: We report a pediatric case of intrathecal baclofen therapy for severe spasticity following traumatic brain injury. A 14-year-old boy suffered from traumatic brain injury by traffic accident in 2005. Subsequently, he experienced tetraparesis and severe spasticity with spontaneous spasms. He underwent baclofen screening test, and his spasticity was improved. Thereafter intrathecal baclofen therapy was performed. Following baclofen pump implantation, Ashworth Score decreased from 4.0 points to 3.0 in lower limbs, and from 3.0 to 1.5 in upper limbs. His muscle tone was reduced and occurrence of spontaneous spasms stopped. Intrathecal baclofen therapy was observed to be an effective treatment for severe spasticity in childhood. Since children receiving the therapy demonstrated longer survival period than adults, long-term follow-up of this therapy is warranted.
authors.affiliation: Department of Neurosurgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Matsuda
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Nishimura
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Hirabayashi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Motoyama
authors.forename: Hideaki
authors.initials: H
authors.lastname: Mishima
authors.forename: Young-Su
authors.initials: YS
authors.lastname: Park
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakase
authors.forename: Toshisuke
authors.initials: T
authors.lastname: Sakaki
mesh_terms: D000293:Adolescent; D001418:Baclofen / Q000008:administration & dosage*; D001930:Brain Injuries / Q000150:complications*; D006801:Humans; D015918:Infusion Pumps, Implantable; D007278:Injections, Spinal; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage*; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen