[Functional anatomy of the cochlear nerve and the central auditory system].
The auditory pathways are a system of afferent fibers (through the cochlear nerve) and efferent fibers (through the vestibular nerve), which are not limited to a simple information transmitting system but create a veritable integration of the sound stimulus at the different levels, by analyzing its three fundamental elements: frequency (pitch), intensity, and spatial localization of the sound source. From the cochlea to the primary auditory cortex, the auditory fibers are organized anatomically in relation to the characteristic frequency of the sound signal that they transmit (tonotopy). Coding the intensity of the sound signal is based on temporal recruitment (the number of action potentials) and spatial recruitment (the number of inner hair cells recruited near the cell of the frequency that is characteristic of the stimulus). Because of binaural hearing, commissural pathways at each level of the auditory system and integration of the phase shift and the difference in intensity between signals coming from both ears, spatial localization of the sound source is possible. Finally, through the efferent fibers in the vestibular nerve, higher centers exercise control over the activity of the cochlea and adjust the peripheral hearing organ to external sound conditions, thus protecting the auditory system or increasing sensitivity by the attention given to the signal.
Simon
E
E
Service de neurochirurgie A, hôpital neurologique Pierre-Wertheimer, hospices civils de Lyon, 69003 Lyon, France. emile.simon@chu-lyon.fr
Perrot
X
X
Mertens
P
P
D000818:Animals; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology; D001306:Auditory Pathways / Q000033:anatomy & histology* / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology; D002490:Central Nervous System / Q000033:anatomy & histology* / Q000502:physiology*; D003051:Cochlea / Q000033:anatomy & histology / Q000294:innervation; D003056:Cochlear Nerve / Q000033:anatomy & histology*; D005829:Geniculate Bodies / Q000033:anatomy & histology / Q000502:physiology; D006309:Hearing / Q000502:physiology; D006801:Humans; D007245:Inferior Colliculi / Q000033:anatomy & histology / Q000502:physiology; D009847:Olivary Nucleus / Q000502:physiology