Effects of vascular bundle implantation on autograft, fresh-frozen allograft, and xenograft incorporation in a rabbit model.
This study examined the effects of vascular bundle implantation into a bone graft. Vascularized and nonvascularized autografts, allografts, and xenografts were placed inside defects in the proximal tibia in rabbits. Evaluation using radiographs, magnetic resonance imaging, bone scintigraphy, and microscopy showed autografts fused more rapidly than allografts and xenografts, and the majority of the vascularized grafts were incorporated completely. Autografts emerged as the gold standard. These findings indicate vessel implantation enhances and accelerates vascularization, new bone formation, and incorporation in autografts, allografts, and xenografts.
Ozyurek
Ayhan
A
Department of Orthopedics and Traumatology, Private Onur Hospital, Silivri, Istanbul, Turkey.
Leblebicioglu
Gursel
G
Bilgili
Hasan
H
Kurum
Baris
B
Gedikoglu
Gokhan
G
Atasever
Tamer
T
Tacal
Tugra
T
Doral
Mahmut Nedim
MN
D000818:Animals; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D015925:Cryopreservation; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D011817:Rabbits; D013977:Tibia / Q000098:blood supply* / Q000637:transplantation*; D013978:Tibial Fractures / Q000175:diagnosis / Q000601:surgery*; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014182:Transplantation, Autologous / Q000379:methods*; D014183:Transplantation, Heterologous / Q000379:methods*; D016896:Treatment Outcome