title: Management of burn injuries--recent developments in resuscitation, infection control and outcomes research.
abstract: BACKGROUND
  Burn injury and its subsequent multisystem effects are commonly encountered by acute care practitioners. Resuscitation is the major component of initial burn care and must be managed to restore and preserve remote organ function. Later complications of burn injury are dominated by infection. Burn centers are often called to manage soft tissue problems outside thermal injury including soft tissue infection and Toxic Epidermal Necrolysis.
  
  
  METHODS
  A selected review of recent reports published by the American Burn Association is provided.
  
  
  RESULTS
  The burn-injured patient is easily and frequently over resuscitated with complications including delayed wound healing and respiratory compromise. A feedback protocol is designed to limit the occurrence of excessive resuscitation has been proposed but no new "gold standard" for resuscitation has replaced the Parkland formula. Significant additional work has been included in recent guidelines identifying specific infectious complications and criteria for these diagnoses in the burn-injured patient. While new medical therapies have been proposed for patients sustaining inhalation injury, a new standard of medical therapy has not emerged. Renal failure as a contributor to adverse outcome in burns has been reinforced by recent data generated in Scandinavia. Of special problems addressed in burn centers, soft tissue infections and Toxic Epidermal Necrolysis have been reviewed but new treatment strategies have not been identified. The value of burn centers in management of burns and other soft tissue problems is supported in several recent reports.
  
  
  CONCLUSIONS
  Recent reports emphasize the dangers of over resuscitation in the setting of burn injury. No new medical therapy for inhalation injury exists but new standards for description of burn-related infections have been presented. The value of the burn center in care of soft tissue problems including Toxic Epidermal Necrolysis and soft tissue infections is supported in recent papers.
authors.affiliation: Regions Hospital, Department of Surgery, St. Paul, MN 55101, USA. david.j.dries@healthpartners.com
authors.forename: David J
authors.initials: DJ
authors.lastname: Dries
mesh_terms: D002056:Burns / Q000382:microbiology / Q000628:therapy*; D005440:Fluid Therapy; D006801:Humans; D017053:Infection Control; D055370:Lung Injury; D009765:Obesity; D017063:Outcome Assessment, Health Care; D012151:Resuscitation / Q000379:methods; D012196:Review Literature as Topic; D018805:Sepsis / Q000517:prevention & control