title: Palladium catalyzed tandem ring opening-ring closing reaction of diazabicyclic alkenes: a facile one pot strategy for cyclopentannulation of heterocycles.
abstract: A novel palladium catalyzed protocol for the synthesis of cyclopentene fused heterocycles from diazabicyclic alkenes and ortho-functionalized aryliodides has been elaborated. The reaction can be tuned toward the formation of either 3,4-disubstituted cyclopentenes or cyclopentene fused heterocycles by careful manipulation of the reaction parameters. A number of cyclopentene fused benzofurans and indole derivatives were prepared in excellent yield by utilizing the developed methodology.
authors.affiliation: Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India.
authors.forename: Jubi
authors.initials: J
authors.lastname: John
authors.forename: U
authors.initials: U
authors.lastname: Indu
authors.forename: Eringathodi
authors.initials: E
authors.lastname: Suresh
authors.forename: K V
authors.initials: KV
authors.lastname: Radhakrishnan