title: [Actinomadura madurae mycetoma of the foot. Report of one case].
abstract: Mycetoma is a chronic infection that affects skin, subcutaneous tissue and bone. Its etiology can be mycotic or bacterial. It affects mainly the lower extremities of middle age men living in tropical climates. We report a 44-year-old male living in a template zone, consulting for swelling and pain in the left foot, lasting for 10 years. Physical examination showed a swollen left foot with hyperpigmented skin and a few crusted papules. Radiology showed an extensive bone involvement of the midfoot with several oval and radiolucid images. Magnetic resonance showed soft and bone tissue involvement, with multiple oval and low intensity images in T1 and T2. The biopsy was compatible with an unspecific chronic osteomyelitis. A bacterial identiFcation by polymerase chain reaction and sequencing in the biopsy determined the presence of an Actinomadumra madurae. Treatment with cotrimaxazol was started.
authors.affiliation: Departamento de Ortopedia y Traumatología, Pontificia Universidad Católica de Chile. jfilippi@med.puc.cl
authors.forename: Jorge
authors.initials: J
authors.lastname: Filippi
authors.forename: Felipe
authors.initials: F
authors.lastname: Quezada
authors.forename: Marcela
authors.initials: M
authors.lastname: Lagos
authors.forename: García
authors.initials: G
authors.lastname: Patricia
mesh_terms: D000192:Actinomycetales / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D005533:Foot Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008271:Mycetoma / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination