Collagen mechanics: a rationale for radiofrequency energy to treat mitral regurgitaton.
Despite a variety of pharmacological interventions to limit the regurgitant fraction, mitral regurgitation requires surgical intervention for definitive treatment. New nonsurgical techniques are being applied to treat mitral regurgitation. The mitral and tricuspid annuli are areas of dense collagen. Application of heat, in the form of radiofrequency energy, can be used to shrink mitral valve annuli and offers a promising approach to the treatment of mitral regurgitation.
Murarka
Shishir
S
Banner Estrella Medical Center, Phoenix, Arizona, USA.
Witzel
Thomas
T
Dickens
Duane
D
Takeda
Patricia A
PA
Heuser
Richard R
RR
D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D000818:Animals; D017115:Catheter Ablation; D003094:Collagen / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008944:Mitral Valve Insufficiency / Q000628:therapy*; D012756:Sheep; D013552:Swine
D003094:Collagen