[Evaluation of immune regulation effects of Chinese medicinal formulae based on immunomics of traditional Chinese medicine].
OBJECTIVE
To investigate the possibility of evaluation the Chinese medicinal formulae with immune regulation effects according to the immunomics of traditional Chinese medicine.


METHODS
The possibility of Chinese medicinal formulae with immune regulation effects was obtained from the discriminant equation of the Chinese medicine with immune regulation effects. The original articles about the Chinese medicinal formulae with immune regulation effects were found since 1980 in CNKI. Using literatures determinate immune effects.


RESULTS
There were 53 kinds, that with calculated determination, from total 60 Chinese medicinal formulae with literatures determinate on immune regulation effects. The coincidence was 88% (53/60). The discriminant score was 0. 89 +/- 0. 03 in group one (there were two or more than two articles have been published to support the medicines immune effects and the articles were finished by different unites independently) and was 0.60 +/- 0.29 in group of random Chinese medicinal formulae. There was a significant deviation (P < 0.05).


CONCLUSIONS
It was proved preliminarily that the principle of calculation presented in this paper is valuable for the immunomics of traditional Chinese medicine.
Liu
Hui
H
Department of Clinic Immunology, Dalian Medical University, Dalian 116044, China. liuhui60@mail.dlptt.ln.cn
Guo
Yue-Qiu
YQ
D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005069:Evaluation Studies as Topic; D006801:Humans; D007107:Immune System / Q000187:drug effects*; D007155:Immunologic Factors / Q000494:pharmacology*; D008516:Medicine, Chinese Traditional
D004365:Drugs, Chinese Herbal; D007155:Immunologic Factors