title: [A clinical study concerning survival of operative cases for the transitional cell carcinoma of the upper urinary tract].
abstract: To identify prognostic factors influencing survival in transitional cell carcinoma (TCC) of the upper urinary tract, we retrospectively studied 189 (median age 70, 130 males and 59 females) patients who underwent surgical resection at our 3 hospitals from August 1980 to September 2006. After a median follow up of 47.8 months, 45 cases (23.8%) died of cancer and the 5-year and 10-year disease-specific survival rate (Kaplan-Meier method) was 70.5 and 67.1%. Because lymphatic and vascular involvements, pattern of infiltration and location of tumor had loss of data, only the univariate analysis was done. They were observed to be significantly different by the univariate analysis. The significant prognostic factors for survival using Cox-proportional hazard models were tumor stage, tumor grade, lymph node metastasis, and surgical margin status. Adjuvant chemotherapy was not the prognostic factor in our multivariate analysis.
authors.affiliation: The Department of Urology, Yokohama Municipal Citizen's Hospital.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yumura
authors.forename: Atushi
authors.initials: A
authors.lastname: Fujikawa
authors.forename: Takehiro
authors.initials: T
authors.lastname: Tajiri
authors.forename: Masaki
authors.initials: M
authors.lastname: Kawai
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Yokomizo
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Moriyama
authors.forename: Sumio
authors.initials: S
authors.lastname: Noguchi
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Ogo
authors.forename: Kazuki
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Senga
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Fujinami
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Kazuto
authors.initials: K
authors.lastname: Okajima
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000401:mortality* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D014571:Urologic Neoplasms / Q000401:mortality* / Q000601:surgery