[A case of resection of synchronous multiple liver metastases from colorectal cancer after FOLFOX chemotherapy].
A 41-year-old man with multiple liver metastases from sigmoid colon cancer received a radical resection of the original tumor and 16 courses of weekly high-dose 5-FU(WHF)chemotherapy via hepatic arterial reservoir. The metastatic lesions showed stable disease(SD), and systemic chemotherapy by mFOLFOX6 was begun via CV port. After 14 courses of mFOLFOX4, abdominal CT revealed liver metastases were remarkably reduced in size. Hepatic resection of lateral segment and radio frequency ablation(RFA)for S6 were enforced, and the patient was uneventfully discharged. Pathological findings of lateral segment revealed no residual cancer cells, indicating that the histological effect of mFOLFOX6 was Grade 3.
Otsuka
Shinya
S
Dept. of Surgery, National Hospital Organization Fukuyama Medical Center.
Inagaki
Masaru
M
Nishie
Manabu
M
Hamano
Ryousuke
R
Tokunaga
Naoyuki
N
Takahashi
Kenji
K
Tsunemitsu
Yousuke
Y
Miyoshi
Kazuya
K
Takahashi
Masahiko
M
Oosaki
Toshihide
T
Iwagaki
Hiromi
H
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008297:Male; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012074:Remission Induction; D014057:Tomography, X-Ray Computed
D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil