title: Pre- and post-operative work-up in patients affected by early cervical cancer and eligible for fertility-sparing treatment: role of MRI with saline hydrocolpos.
abstract: Nowadays young women affected by early invasive uterine cervical cancer (stage IA2-IB1) may be offered a fertility-sparing treatment: the radical trachelectomy with pelvic lymph node dissection. This procedure consists in surgical removal of cervix uteri, proximal parametrial tissue, and vaginal cuff. The morphology and the functions of corpus uteri are preserved. Women candidates for trachelectomy must be closely selected. Gynecologist oncologist needs an imaging modality that can accurately value the tumoral diameter and which can demonstrate proximal extension of tumor to ensure surgical clear resection margins (especially the cranial one). Magnetic resonance imaging (MRI) is a very useful examination in pre-operative study of women affected by early cervical cancer. The aim of this study is to evaluate the role of MRI with hydrocolpos about pre- and post-operative work-up in women eligible for fertility-sparing treatment.
authors.affiliation: Department of Ginecology and Obstetrics, San Martino Hospital, University of Genova, Italy. pmarchiole@yahoo.com
authors.forename: Pierangelo
authors.initials: P
authors.lastname: Marchiolè
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cittadini
authors.forename: Paolo
authors.initials: P
authors.lastname: Sala
authors.forename: Melita
authors.initials: M
authors.lastname: Moioli
authors.forename: Patrice
authors.initials: P
authors.lastname: Mathevet
authors.forename: Enrico
authors.initials: E
authors.lastname: Capaccio
authors.forename: Sergio
authors.initials: S
authors.lastname: Costantini
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000601:surgery*; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000601:surgery*; D002404:Catheterization; D019092:Conization; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D007552:Isotonic Solutions; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D018579:Patient Selection; D012965:Sodium Chloride; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*
chemical_list: D007552:Isotonic Solutions; D012965:Sodium Chloride