title: Primary cutaneous zygomycosis due to Absidia corymbifera in a patient with cutaneous T cell lymphoma.
abstract: A slowly enlarging arm ulcer appeared in a 61-year-old man with cutaneous T cell lymphoma. Skin biopsy revealed aseptate hyphae and nodular small/medium-sized pleomorphic CD4(+) T cell infiltration. Cultures yielded Absidia corymbifera which was identified by phenotypic and molecular methods. Since a thorough examination did not detect organ involvement, the patient was diagnosed as having primary cutaneous zygomycosis. This is the first case report of cutaneous zygomycosis caused by A. corymbifera in a patient with primary cutaneous CD4(+) small/medium-sized pleomorphic T-cell lymphoma. Other cases of primary cutaneous zygomycosis caused by A. corymbifera are also reviewed.
authors.affiliation: Department of Medical Mycology, China Medical Microbiological Culture Collection Center (fungi), Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
authors.forename: Ze-Hu
authors.initials: ZH
authors.lastname: Liu
authors.forename: Gui-Xia
authors.initials: GX
authors.lastname: Lv
authors.forename: Jia
authors.initials: J
authors.lastname: Chen
authors.forename: Hong
authors.initials: H
authors.lastname: Sang
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: She
authors.forename: Xian-Jin
authors.initials: XJ
authors.lastname: Chen
authors.forename: Jian-Fang
authors.initials: JF
authors.lastname: Sun
authors.forename: Yong-Nian
authors.initials: YN
authors.lastname: Shen
authors.forename: Xue-Si
authors.initials: XS
authors.lastname: Zeng
authors.forename: Wei-da
authors.initials: WD
authors.lastname: Liu
mesh_terms: D020095:Absidia / Q000166:cytology / Q000235:genetics / Q000302:isolation & purification*; D001132:Arm / Q000382:microbiology / Q000473:pathology; D004271:DNA, Fungal / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014456:Ulcer / Q000382:microbiology / Q000473:pathology; D020096:Zygomycosis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology
chemical_list: D004271:DNA, Fungal