[Drug therapy during pregnancy].
Most acute and chronic diseases do not require termination of a pregnancy nor is a pregnancy a reason to withhold necessary drug therapy. As many pregnancies are unplanned, any drug treatment during reproductive age should consider the occurrence of a pregnancy. Wherever possible, only medicinal drugs with sufficient documentation in pregnant women not indicating developmental toxicity should be chosen. There are acceptable drugs for the majority of diseases, although many of them are labeled as contraindicated during pregnancy. This article provides an overview on prenatal risks of ACE-inhibitors, AT II-receptor antagonists, antiepileptics, SSRI, atypical neuroleptics, lithium, coumarin anticoagulants, retinoids, selected antibiotics, immunomodulatory drugs and provides treatment recommendations for the most common diseases.
Schaefer
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Pharmakovigilanz- und Beratungszentrum für Embryonaltoxikologie, Berliner Betrieb für Zentrale Gesundheitliche Aufgaben, Spandauer Damm 130, Berlin, Germany. schaefer@embryotox.de
Weber-Schoendorfer
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D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced* / Q000175:diagnosis / Q000517:prevention & control*