title: Biliary dilatation secondary to lithiasis in a child affected by Langerhans' cell histiocytosis.
abstract: Langerhans' cell histiocytosis (LCH) is a disease of unknown pathogenesis, caused by clonal proliferation of Langerhans' cells. Liver involvement results in a cholangiopathy, which has the radiologic appearance of sclerosing cholangitis. Only 1 case of obstructive jaundice due to common bile duct stone in a patient with LCH has been described. We present a case of a 31-month-old child with LCH and liver involvement on the waiting list for liver transplantation. During the follow-up, there was a rapid onset of jaundice due to sludge and lithiasis. The patient was treated first with an endoscopic biliary plastic stent and then with percutaneous biliary drainage and bilioenteric anastomosis.
authors.affiliation: Department of Radiology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT), Palermo, Italy.
authors.forename: Settimo
authors.initials: S
authors.lastname: Caruso
authors.forename: Roberto
authors.initials: R
authors.lastname: Miraglia
authors.forename: Marco
authors.initials: M
authors.lastname: Spada
authors.forename: Angelo
authors.initials: A
authors.lastname: Luca
authors.forename: Bruno
authors.initials: B
authors.lastname: Gridelli
mesh_terms: D000714:Anastomosis, Surgical; D001649:Bile Duct Diseases / Q000175:diagnosis / Q000209:etiology*; D002675:Child, Preschool; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis / Q000209:etiology*; D020347:Lithiasis / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography