Live from the liver: hepatocyte IL-7.
Interleukin 7 (IL-7), which is required for T cell survival, was previously found in lymphoid tissues. In this issue of Immunity, Sawa et al. (2009) have identified the liver as a new source of IL-7.
Durum
Scott K
SK
Laboratory of Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702-1201, USA. durums@mail.nih.gov
Mazzucchelli
Renata I
RI
D000818:Animals; D022781:Hepatocytes / Q000276:immunology*; D006801:Humans; D007372:Interferons / Q000378:metabolism; D015851:Interleukin-7 / Q000276:immunology*; D008099:Liver / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D051193:Toll-Like Receptors / Q000276:immunology
D015851:Interleukin-7; D051193:Toll-Like Receptors; D007372:Interferons