title: Iron-catalyzed chemoselective ortho arylation of aryl imines by directed C-H bond activation.
abstract: No Fe-ar: Iron catalyzes an imine-directed C-H bond activation to introduce an ortho-aryl group to an acetophenone-derived imine using a diarylzinc reagent (see scheme), whereas palladium catalyzes the conventional substitution reaction . The title reaction features mild and selective C-H bond activation in the presence of aryl bromide, chloride, or sulfonate groups, and 1,2-dichloroisobutane is essential to achieve such selectivity.
authors.affiliation: Department of Chemistry, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Naohiko
authors.initials: N
authors.lastname: Yoshikai
authors.forename: Arimasa
authors.initials: A
authors.lastname: Matsumoto
authors.forename: Jakob
authors.initials: J
authors.lastname: Norinder
authors.forename: Eiichi
authors.initials: E
authors.lastname: Nakamura