title: [Multivariate analysis of risk factors of lymph node metastasis in early gastric cancer].
abstract: OBJECTIVE
  To investigate the clinicopathological factors affecting lymph node metastasis in early gastric cancer(EGC).
  
  
  METHODS
  Clinicopathological data of 369 patients with EGC from Jan. 1999 to Jun. 2008 were analyzed retrospectively. Multivariate analysis was performed to find the risk factors affecting lymph node metastasis.
  
  
  RESULTS
  The age, gender, tumor size, invasion depth, histological classification and vascular cancer thrombosis were associated with lymph node metastasis. Multivariate analysis showed that tumor size and depth of invasion were main independent risk factors.
  
  
  CONCLUSIONS
  The main independent risk factors affecting lymph node metastasis in EGC are tumor size and invasion depth. The gender, vascular cancer thrombosis, tumor size, invasion depth and histological classification should be considered to establish the surgical program.
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Fang
authors.forename: Dong-bing
authors.initials: DB
authors.lastname: Zhao
authors.forename: Jian-guo
authors.initials: JG
authors.lastname: Zhou
authors.forename: Jian-qiang
authors.initials: JQ
authors.lastname: Cai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D016015:Logistic Models; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000473:pathology*