Selective anion binding in water with use of a zinc(II) dipicolylamino functionalized diketopiperazine scaffold.
The design and synthesis of a diketopiperazine based anion receptor bearing two dipicolylamino arms complexed to zinc(II) ions is described. This receptor is readily prepared from the dipeptide precursor by a microwave-assisted intramolecular cyclization reaction. Upon addition of zinc(II), the receptor binds di- and triphosphate ions with high affinity and selectivity in aqueous solution, as determined by using a fluorescent indicator displacement assay.
Carolan
Jessica Veliscek
JV
School of Chemistry, The University of Sydney, 2006, NSW, Australia.
Butler
Stephen J
SJ
Jolliffe
Katrina A
KA