title: Recent clinical trials and future therapies.
abstract: Immunotherapy for multiple sclerosis (MS) has developed extremely successfully during the past decade and a number of new strategies were developed for the treatment of the disease. Examples include therapeutic strategies targeting leukocyte differentiation molecules, costimulatory molecules, anti-adhesion molecules, chemotaxis, novel immunomodulators, autologous stem cell transplantation, anti-infectious therapies and strategies for neuroprotection, neurorepair and remyelination. Here we describe examples of monoclonal antibodies, a novel immunosuppressant and interesting neuroprotective strategies.
authors.affiliation: Universität Würzburg, Klinik und Poliklinik für Neurologie, Josef-Schneider Str. 11, 97080 Würzburg, Germany. meuth_s@klinik.uni-wuerzburg.de
authors.forename: Sven G
authors.initials: SG
authors.lastname: Meuth
authors.forename: Christoph
authors.initials: C
authors.lastname: Kleinschnitz
authors.forename: Heinz
authors.initials: H
authors.lastname: Wiendl
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends; D006801:Humans; D007167:Immunotherapy / Q000379:methods* / Q000639:trends; D009103:Multiple Sclerosis / Q000276:immunology / Q000628:therapy*; D018696:Neuroprotective Agents / Q000627:therapeutic use*
chemical_list: D018696:Neuroprotective Agents