Iron-catalysed Negishi coupling of benzyl halides and phosphates.
Iron-based catalysts containing either 1,2-bis(diphenylphosphino)benzene or 1,3-bis(diphenylphosphino)propane give excellent activity and good selectivity in the Negishi coupling of aryl zinc reagents with a range of benzyl halides and phosphates.
Bedford
Robin B
RB
School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK BS8 1TS. r.bedford@bristol.ac.uk
Huwe
Michael
M
Wilkinson
Mark C
MC
D001555:Benzene Derivatives / Q000737:chemistry*; D001593:Benzyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D011407:Propane / Q000031:analogs & derivatives* / Q000737:chemistry; D015032:Zinc / Q000737:chemistry
C519449:1,2-bis(diphenylphosphino)benzene; D001555:Benzene Derivatives; D001593:Benzyl Compounds; D006846:Hydrocarbons, Halogenated; D063065:Organophosphonates; D010710:Phosphates; D010720:Phosphines; C467590:1,3-bis(diphenylphosphino)propane; D007501:Iron; D015032:Zinc; D011407:Propane