title: [Follow-up survey on the imported cases of lymphatic filariasis in Guangdong Province].
abstract: OBJECTIVE
  To make a survey on the possible imported cases with microfilaremia from a recently identified outbreak focus in Fuchuan County of Guangxi Region.
  
  
  METHODS
  Moving people as temporary laborers from Guangxi and periphery residents were screened by thick blood smears for microfilariae and ELISA for specific IgG4 in Sept 2007.
  
  
  RESULTS
  989 persons in cities/districts of Nansha, Panyu, Shantou and Zhongshan were investigated. Among 150 persons from Changtang administrative village of Guangxi, 47 were from two outbreak focuses, Ganshang and Yinshan natural villages in Changtang. Three cases with microfilaremia were found, with a microfilaraemia density of 24, 20 and 2 per 120 microl blood, respectively. The 3 cases were all from the 2 natural villages, with a microfilaraemia positive rate of 6.4% (3/47). Meanwhile, anti-filaria IgG4 was detected for other 1 501 persons, including those from the outbreak focuses, from surr-founding areas and from non-endemic area as control, fifteen cases were found with IgG4 positive. Of the 15 positive cases, 12 were from the 2 outbreak natural villages, with a positive rate of 25.5%, higher than those of others (chi2=295.83, P < 0.01). The cases with IgG4 positive but microfilaremia negative were reexamined by ICT kit and all showed negative.
  
  
  CONCLUSIONS
  It is suggested that no further transmission occurs although microfilaremia cases have been imported from the outbreak focus of Guangxi.
authors.affiliation: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors.forename: Xian-chang
authors.initials: XC
authors.lastname: Zhang
authors.forename: Shao-yu
authors.initials: SY
authors.lastname: Huang
authors.forename: Zhuo-hui
authors.initials: ZH
authors.lastname: Deng
authors.forename: Zuo-yan
authors.initials: ZY
authors.lastname: Ou
authors.forename: Wei-ping
authors.initials: WP
authors.lastname: Wu
authors.forename: Xiong-cai
authors.initials: XC
authors.lastname: Luo
authors.forename: Xi-xin
authors.initials: XX
authors.lastname: Chen
authors.forename: Qi-ming
authors.initials: QM
authors.lastname: Zhang
authors.forename: Rong-xing
authors.initials: RX
authors.lastname: Lin
authors.forename: Cai-wen
authors.initials: CW
authors.lastname: Ruan
authors.forename: Jin-long
authors.initials: JL
authors.lastname: Wang
authors.forename: Hui-er
authors.initials: HE
authors.lastname: Cui
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis* / Q000097:blood; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D004605:Elephantiasis, Filarial / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000032:analysis* / Q000097:blood; D008842:Microfilariae / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000909:Antibodies, Helminth; D007074:Immunoglobulin G