Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience.
Saumier
D
D
BELLUS Health Inc., 275 boul. Armand-Frappier, Laval, Quebec, Canada.
Aisen
P S
PS
Gauthier
S
S
Vellas
B
B
Ferris
S H
SH
Duong
A
A
Suhy
J
J
Oh
J
J
Lau
W
W
Garceau
D
D
Haine
D
D
Sampalis
J
J
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy*; D000682:Amyloid / Q000037:antagonists & inhibitors*; D004311:Double-Blind Method; D005260:Female; D018755:GABA Agonists / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012107:Research Design; D012680:Sensitivity and Specificity; D013654:Taurine / Q000031:analogs & derivatives / Q000627:therapeutic use
D000682:Amyloid; D018755:GABA Agonists; D013654:Taurine; C001355:tramiprosate