Diabetic muscle infarction in association with terlipressin therapy: a case report.
Diabetic muscle infarction (DMI) is a rare complication that often exists in long-standing diabetic patients. Clinically, it presents with pain, swelling and sometimes a palpable mass, and is often misdiagnosed as soft tissue infection. The athogenesis of DMI is uncertain. We present the case of a type 2 diabetic patient with liver cirrhosis who was diagnosed with muscle infarction after being treated with terlipressin for gastrointestinal bleeding. This 45-year-old male complained of increasing pain in his right posterior thigh after treatment with terlipressin for 2 days. He was initially diagnosed with soft tissue infection, but he responded poorly to antibiotic treatment. Magnetic resonance imaging suggested acute muscle infarction. We performed a muscle biopsy and the pathologist reported that the muscle was necrotic. After 5 days of bed rest, the patient was able to walk and was discharged uneventfully.
Chang
Yu-Hung
YH
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Yen
Feng-Chieh
FC
Hsieh
Ming-Chia
MC
Lin
Kun-Der
KD
Shin
Shyi-Jang
SJ
Hsin
Shih-Chieh
SC
D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007238:Infarction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008236:Lypressin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D000077585:Terlipressin
D008236:Lypressin; D000077585:Terlipressin