title: Racial disparities in pancreatic cancer and radon exposure: a correlation study.
abstract: OBJECTIVE
  To correlate radon exposure with the incidence of pancreatic cancer (PC) and to ascertain the influence of race in this correlation.
  
  
  METHODS
  Age-standardized incidence rates (SIRs) of PC from 1992 to 2002, segregated by race, were obtained from the Surveillance, Epidemiology, and End Results database. The mean radon levels for each county were obtained from the Environmental Protection Agency map, which assigns each county to 1 of 3 categories based on radon potential. Aggregate radon exposure was correlated to the aggregate SIRs of PC.
  
  
  RESULTS
  The SIRs of PC in the United States ranged from 1.4 to 21.8/100,000 person-years. The highest rates for whites (19.6/100,000 person-years) and American Indians (594/100,000 person-years) were found in Guadalupe County, New Mexico; for African Americans (4845/100,000 person-years) in Worth County, Iowa; and for Asian Americans (3177/100,000 person-years) in Monroe County, Iowa. There was an insignificant correlation between radon exposure and overall incidence of PC (r = 0.042). A significant correlation existed between radon exposure and incidence of PC in African Americans, American Indians, and Asian Americans, but not in whites.
  
  
  CONCLUSIONS
  Radon exposure may be a significant risk factor for PC in African Americans, American Indians, and Asian Americans. Testing and mitigating homes for indoor radon may decrease PC incidence in these groups.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch, Galveston, TX, USA.
authors.forename: Nischita K
authors.initials: NK
authors.lastname: Reddy
authors.forename: Manoop S
authors.initials: MS
authors.lastname: Bhutani
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D001213:Asian / Q000706:statistics & numerical data; D004463:Ecology; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D005843:Geography; D006801:Humans; D015994:Incidence; D007198:Indians, North American / Q000706:statistics & numerical data; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D010190:Pancreatic Neoplasms / Q000208:ethnology* / Q000209:etiology; D011886:Radon; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data
chemical_list: D011886:Radon