[Anterior pituitary lobe atrophy as late complication of hemorrhagic fever with renal syndrome].
BACKGROUND
Hemorrhagic fever with renal syndrome (HFRS) is acute infective multisystemic disease followed by febrility, hemorrhages and acute renal insufficiency. Bleeding in the anterior pituitary lobe leading to tissue necrosis occurs in acute stage of severe clinical forms of HFRS, while atrophy of the anterior pituitary lobe with diminution of the gland function occurs after recovery stage.


METHODS
We presented a patient with the development of chronic renal insufficiency and hypopituitarism as complication that had been diagnosed six years after Hantavirus infection. Magnetic resonance of the pituitary gland revealed atrophy and empty sella turcica.


CONCLUSIONS
Regarding frequency of this viral infection and its endemic character in some parts of our country partial and/or complete loss of pituitary function should be considered during the late stage of HFRS.
Jovanović
Dragan
D
Vojnomedicinska akademija, Klinika za nefrologiju, Beograd.
Kovacević
Zoran
Z
Dragović
Tamara
T
Petrović
Marijana
M
Tadić
Jelena
J
D000328:Adult; D001284:Atrophy; D004652:Empty Sella Syndrome / Q000209:etiology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D010903:Pituitary Gland, Anterior / Q000473:pathology*