An efficient protocol for the synthesis of 2-amino-4,6-diphenylpyridine-3-carbonitrile using ionic liquid ethylammonium nitrate.
Chalcones on condensation with malononitrile and ammonium acetate in the presence of ionic liquid ethylammonium nitrate affords the corresponding 2-amino-4, 6-diphenylpyridine-3-carbonitrile in excellent yield. The ionic liquid is recycled and reused several times.
Sarda
Swapnil R
SR
Department of Chemistry, JES College, Jalna, 431203, MS, India.
Kale
Jagpal D
JD
Wasmatkar
Sunil K
SK
Kadam
Vijay S
VS
Ingole
Pravin G
PG
Jadhav
Wamanrao N
WN
Pawar
Rajendra P
RP
D002384:Catalysis; D052578:Ionic Liquids / Q000737:chemistry*; D009570:Nitriles / Q000138:chemical synthesis*; D011725:Pyridines / Q000138:chemical synthesis*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
C547094:2-amino-4,6-diphenylpyridine-3-carbonitrile; D052578:Ionic Liquids; D009570:Nitriles; D011725:Pyridines; D000644:Quaternary Ammonium Compounds; D012997:Solvents; C421484:ethylammonium