Development of a new design (125)I-brachytherapy seed for its application in the treatment of eye and prostate cancer.
Palladium coated silver beads of 0.5mm (slashed circle) were used to adsorb (125)I and encapsulated inside a titanium capsule by Nd:YAG laser, for use as a brachytherapy source. Experimental conditions were optimized for maximum adsorption of (125)I and uniformity of radioactivity was ascertained. Leachability of (125)I was found to be<0.01%. The dose rate constant of the new source was estimated to be 1.045cGyh(-1)U(-1). This newly developed source could be an alternative to other (125)I sources.
Saxena
Sanjay Kumar
SK
Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai 400 085, India.
Sharma
S D
SD
Dash
Ashutosh
A
Venkatesh
Meera
M
D000327:Adsorption; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D004339:Drug Compounding; D004867:Equipment Design; D005134:Eye Neoplasms / Q000532:radiotherapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage*; D008297:Male; D008863:Microspheres; D010165:Palladium; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011829:Radiation Dosage; D012834:Silver
D007457:Iodine Radioisotopes; D012834:Silver; D010165:Palladium