Psychopharmacologic management of opioid-dependent women during pregnancy.
Illicit drug use during pregnancy presents complex clinical challenges, including reducing drug use and treating psychiatric disorders. Pharmacologic treatment of psychiatric disorders in a pregnant woman requires an evaluation of the balance between potential clinical benefit and the risk of potential neonatal consequences. This study describes psychiatric symptoms in 111 opioid-dependent pregnant women and their prescribed psychotropic medications. Hypomania, generalized anxiety disorder and depression were the most common disorders for which psychiatric symptoms were endorsed. Over half of women studied were prescribed some form of psychoactive medication during pregnancy. Pharmacologic vs. non-pharmacologic treatment approaches in this patient population are discussed.
Martin
Peter R
PR
Vanderbilt University School of Medicine, Nashville, Tennessee, USA. peter.martin@vanderbilt.edu
Arria
Amelia M
AM
Fischer
Gabriele
G
Kaltenbach
Karol
K
Heil
Sarah H
SH
Stine
Susan M
SM
Coyle
Mara G
MG
Selby
Peter
P
Jones
Hendrée E
HE
D000328:Adult; D001008:Anxiety Disorders / Q000188:drug therapy; D001714:Bipolar Disorder / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology; D009293:Opioid-Related Disorders / Q000150:complications* / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use*
D011619:Psychotropic Drugs