Recent clinical trials and future therapies.
Immunotherapy for multiple sclerosis (MS) has developed extremely successfully during the past decade and a number of new strategies were developed for the treatment of the disease. Examples include therapeutic strategies targeting leukocyte differentiation molecules, costimulatory molecules, anti-adhesion molecules, chemotaxis, novel immunomodulators, autologous stem cell transplantation, anti-infectious therapies and strategies for neuroprotection, neurorepair and remyelination. Here we describe examples of monoclonal antibodies, a novel immunosuppressant and interesting neuroprotective strategies.
Meuth
Sven G
SG
Universität Würzburg, Klinik und Poliklinik für Neurologie, Josef-Schneider Str. 11, 97080 Würzburg, Germany. meuth_s@klinik.uni-wuerzburg.de
Kleinschnitz
Christoph
C
Wiendl
Heinz
H
D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends; D006801:Humans; D007167:Immunotherapy / Q000379:methods* / Q000639:trends; D009103:Multiple Sclerosis / Q000276:immunology / Q000628:therapy*; D018696:Neuroprotective Agents / Q000627:therapeutic use*
D018696:Neuroprotective Agents