Extragastrointestinal stromal tumor arising in the rectovaginal septum: report of an unusual case with literature review.
BACKGROUND
Extragastrointestinal stromal tumor (EGIST) is a rare tumor that shows features of gastrointestinal stromal tumor (GIST) outside the gastrointestinal tract, but EGIST arising in the rectovaginal septum is extremely rare.


METHODS
We report a unique case of a 42-year-old woman with EGIST in rectovaginal septum. The tumor was excised locally. The patient is healthy without evidence of recurrence 11 months after surgery.


CONCLUSIONS
The clinical features and treatment of EGIST are not well known because few cases have been reported. Pathologically, immunohistochemistry with antibody against c-kit protein (CD117) is valuable for diagnosis of EGIST. Mitotic rate is the most reliable prognostic factor, and mutations in KIT may be a clinically useful adjunct marker in the evaluation. Surgery is the most effective treatment, and long-term follow-up is necessary.
Zhang
Wenjing
W
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Peng
Zhilan
Z
Xu
Lian
L
D000328:Adult; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000601:surgery
D019394:Ki-67 Antigen