title: Diagnostic assay of chromium (VI) in the ex vivo fluid of the urine of a smoker using a fluorine-doped handmade sensor.
abstract: A voltammetric diagnosis of a chromium (VI) ion was investigated using a fluorine-doped graphite pencil electrode. Square wave (SW) stripping working conditions were attained at a high range of 0.051-0.45 mg L(-1) and a microrange of 0.05-0.4 microg L(-1) in a 0.1 M NH(4)H(2)PO(4) electrolyte solution, at a relative standard deviation of 1.68% (RSD, n=15), using 10.0 microg L(-1) Cr(VI). A fast experimental time was used only for the 120 sec SW accumulation time. An analytical detection-limit (DL) of 0.008 microg L(-1) was attained. DL appeared to be more sensitive than common voltammetric and spectrophotometric assays. The developed sensor was applied to tap water and the urine of a smoker. It was found that the methods can be applicable for in vivo fluid or medicinal diagnosis.
authors.affiliation: Biosensor Research Institute, Seoul National University of Technology, 172 gongreung 2-dong, Nowon-gu, Seoul, South Korea. suwyoung@snut.ac.kr
authors.forename: Suw Young
authors.initials: SY
authors.lastname: Ly
authors.forename: Min Joon
authors.initials: MJ
authors.lastname: Kim
mesh_terms: D002857:Chromium / Q000652:urine*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D005461:Fluorine / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry; D006801:Humans; D016014:Linear Models; D012680:Sensitivity and Specificity; D012907:Smoking / Q000652:urine*; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D002857:Chromium; C074702:chromium hexavalent ion; D005461:Fluorine; D006108:Graphite