title: Production of Sn-117m in the BR2 high-flux reactor.
abstract: The BR2 reactor is a 100MW(th) high-flux 'materials testing reactor', which produces a wide range of radioisotopes for various applications in nuclear medicine and industry. Tin-117m ((117m)Sn), a promising radionuclide for therapeutic applications, and its production have been validated in the BR2 reactor. In contrast to therapeutic beta emitters, (117m)Sn decays via isomeric transition with the emission of monoenergetic conversion electrons which are effective for metastatic bone pain palliation and radiosynovectomy with lesser damage to the bone marrow and the healthy tissues. Furthermore, the emitted gamma photons are ideal for imaging and dosimetry.
authors.affiliation: Belgian Nuclear Research Centre (SCK.CEN), BR2 Reactor, Boeretang 200, B-2400 Mol, Belgium. bponsard@sckcen.be
authors.forename: B
authors.initials: B
authors.lastname: Ponsard
authors.forename: S C
authors.initials: SC
authors.lastname: Srivastava
authors.forename: L F
authors.initials: LF
authors.lastname: Mausner
authors.forename: F F
authors.initials: FF
authors.lastname: Russ Knapp
authors.forename: M A
authors.initials: MA
authors.lastname: Garland
authors.forename: S
authors.initials: S
authors.lastname: Mirzadeh
mesh_terms: D004583:Electrons; D005720:Gamma Rays; D009683:Nuclear Medicine / Q000295:instrumentation* / Q000379:methods; D011876:Radionuclide Generators; D014004:Tin Radioisotopes / Q000737:chemistry* / Q000627:therapeutic use
chemical_list: D014004:Tin Radioisotopes