title: The study of some polyphenolic compounds from Melissa officinalis L. (Lamiaceae).
abstract: We proposed the analyses of polyphenolic coumpounds from the Melissa officinalis L. (Lamiaceae) leaves obtained from Medicinal Plant Collection of USAMV Cluj-Napoca.
  
  
  METHODS
  The study was performed by using spectrophotometric (I) and HPLC methods (II).
  
  
  RESULTS
  The vegetal product contains 0.64% flavonoids expressed in rutoside and 8,962% phenyl-propane derivatives expressed in caffeic acid (I). HPLC analyses (II) were made after extraction of studied compounds from leaves with ethyl-ether, ethyl acetate and 1-buthanol. These extracts were analyzed before and after the hydrolysis of compounds. There were identified 6 polyphenolic compounds: caftaric acid, caffeic acid, p-cumaric acid, ferulic acid, luteolin and apigenin.
  
  
  CONCLUSIONS
  The extracted amount of these compounds in chosen solvents depending of their polarity.
authors.affiliation: Department of Pharmacognosis, School of Pharmacy, "I. Haţieganu" University of Medicine and Pharmacy Cluj-Napoca.
authors.forename: Daniela
authors.initials: D
authors.lastname: Hanganu
authors.forename: L
authors.initials: L
authors.lastname: Vlase
authors.forename: Lorena
authors.initials: L
authors.lastname: Filip
authors.forename: Camelia
authors.initials: C
authors.lastname: Sand
authors.forename: Simona
authors.initials: S
authors.lastname: Mirel
authors.forename: L L
authors.initials: LL
authors.lastname: Indrei
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D047310:Apigenin / Q000737:chemistry; D001565:Benzoates / Q000737:chemistry; D002109:Caffeic Acids / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003373:Coumaric Acids / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D047311:Luteolin / Q000737:chemistry; D031334:Melissa / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D059808:Polyphenols; D012431:Rutin / Q000737:chemistry / Q000494:pharmacology; D013053:Spectrophotometry / Q000379:methods
chemical_list: D000975:Antioxidants; D001565:Benzoates; D002109:Caffeic Acids; D003373:Coumaric Acids; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols; D012431:Rutin; C055607:cumic acid; D047310:Apigenin; C004999:ferulic acid; D047311:Luteolin; C040048:caffeic acid; C515101:caftaric acid