Primary cutaneous zygomycosis due to Absidia corymbifera in a patient with cutaneous T cell lymphoma.
A slowly enlarging arm ulcer appeared in a 61-year-old man with cutaneous T cell lymphoma. Skin biopsy revealed aseptate hyphae and nodular small/medium-sized pleomorphic CD4(+) T cell infiltration. Cultures yielded Absidia corymbifera which was identified by phenotypic and molecular methods. Since a thorough examination did not detect organ involvement, the patient was diagnosed as having primary cutaneous zygomycosis. This is the first case report of cutaneous zygomycosis caused by A. corymbifera in a patient with primary cutaneous CD4(+) small/medium-sized pleomorphic T-cell lymphoma. Other cases of primary cutaneous zygomycosis caused by A. corymbifera are also reviewed.
Liu
Ze-Hu
ZH
Department of Medical Mycology, China Medical Microbiological Culture Collection Center (fungi), Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Lv
Gui-Xia
GX
Chen
Jia
J
Sang
Hong
H
She
Xiao-Dong
XD
Chen
Xian-Jin
XJ
Sun
Jian-Fang
JF
Shen
Yong-Nian
YN
Zeng
Xue-Si
XS
Liu
Wei-da
WD
D020095:Absidia / Q000166:cytology / Q000235:genetics / Q000302:isolation & purification*; D001132:Arm / Q000382:microbiology / Q000473:pathology; D004271:DNA, Fungal / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014456:Ulcer / Q000382:microbiology / Q000473:pathology; D020096:Zygomycosis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology
D004271:DNA, Fungal