Castleman's Disease. A Review.
Castleman's disease is characterized by a non-clonal lymph node hyperplasia. Pathologically it is classified as hyaline vascular, plasmacytic, or mixed cellularity types, and clinically it may adopt a unicentric (localized) or multicentric presentation. An association of the disease with HIV infection has been found. Many uncertainties remain concerning the etiopathogenesis and the optimal treatment of this rare condition.
Roca
Bernardino
B
Medicine and Infectious Disease Department, Hospital General of Castellon, University of Valencia, Valencia, Spain. brocav@meditex.es
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D005871:Castleman Disease / Q000150:complications / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006818:Hyalin; D008297:Male; D010950:Plasma Cells / Q000473:pathology; D013792:Thalidomide / Q000627:therapeutic use
D020533:Angiogenesis Inhibitors; D000998:Antiviral Agents; D005938:Glucocorticoids; D013792:Thalidomide