title: A supramolecular polymer as a self-assembling polyvalent scaffold.
abstract: Binding bacteria: Discotic molecules self-assemble into columnar supramolecular polymers that show strong polyvalent binding to bacteria by virtue of mannose ligands attached at their periphery (orange; see picture). The reversible formation of the supramolecular polymers allows simple mixing of differently substituted monomers and the optimization of bacterial aggregation.
authors.affiliation: Department of Chemical Biology, Max Planck Institute for Molecular Physiology and Chemical Genomics Centre, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany.
authors.forename: Marion K
authors.initials: MK
authors.lastname: Müller
authors.forename: Luc
authors.initials: L
authors.lastname: Brunsveld
mesh_terms: D004926:Escherichia coli / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry; D008358:Mannose / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D011108:Polymers; D008358:Mannose