title: History of the genesis of detachable coils. A review.
abstract: The genesis of detachable coils and the background of this genesis are described in this article. To frame the beginning developmental stages of the discovery of detachable coils, the previous extravascular-intravascular and endovascular techniques are presented, as well as the development of the various delivery systems. The experimental studies, initial clinical application, and crucial moment of the conception of detachable coils are also reported.
authors.affiliation: Department of Neurosciences, University of Rome La Sapienza, Rome, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Guglielmi
mesh_terms: D004621:Embolization, Therapeutic / Q000266:history* / Q000295:instrumentation; D049673:History, 20th Century; D006801:Humans; D002532:Intracranial Aneurysm / Q000266:history* / Q000628:therapy