title: Performance of four carbon dioxide absorbents in experimental and clinical settings.
abstract: To evaluate the performance of four kinds of carbon dioxide (CO(2)) absorbents (Medisorb GE Healthcare, Amsorb Plus Armstrong Medical, YabashiLime Yabashi Industries, and Sodasorb LF Grace Performance Chemicals), we measured their dust production, acceptability of colour indicator, and CO(2) absorption capacity in in vitro experimental settings and the concentration of compound A in an inspired anaesthetic circuit during in vivo clinical practice. In vitro, the order of the dust amount was Sodasorb LF > Medisorb > Amsorb Plus = YabashiLime both before and after shaking. The order of the color acceptability was similar: Sodasorb LF > Amsorb Plus = Medisorb > YabashiLime both initially and 16 h after CO(2) exhaustion. During exposure to 200 ml.min(-1) CO(2) in vitro, the period until 1 kg of fresh soda lime allowed inspired CO(2) to increase to 0.7 kPa (as a mark of utilisation of the absorbent) was longer with Medisorb (1978 min) than with the other absorbents (1270-1375 min). In vivo, compound A (1.0% inspired sevoflurane) was detected only when using Medisorb. While Medisorb has the best ability to absorb CO(2), it alone produces compound A.
authors.affiliation: Department of Anaesthesiology, Sapporo Medical University School of Medicine, Sapporo, Japan. yamakage@sapmed.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Yamakage
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: J-I
authors.initials: JI
authors.lastname: Satoh
authors.forename: A
authors.initials: A
authors.lastname: Namiki
mesh_terms: D000042:Absorption; D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation*; D018685:Anesthetics, Inhalation / Q000737:chemistry; D002122:Calcium Chloride / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry; D002126:Calcium Hydroxide / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D003116:Color; D004391:Dust; D004987:Ethers / Q000737:chemistry; D015920:Gas Scavengers; D006801:Humans; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D007202:Indicators and Reagents; D008738:Methyl Ethers / Q000737:chemistry; D010087:Oxides / Q000737:chemistry; D000077149:Sevoflurane; D012972:Sodium Hydroxide / Q000737:chemistry
chemical_list: C400293:Amsorb; D018685:Anesthetics, Inhalation; D017610:Calcium Compounds; D004391:Dust; D004987:Ethers; D006845:Hydrocarbons, Fluorinated; D007202:Indicators and Reagents; D008738:Methyl Ethers; D010087:Oxides; D002245:Carbon Dioxide; D000077149:Sevoflurane; C004569:soda lime; D012972:Sodium Hydroxide; C078742:fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether; D002122:Calcium Chloride; D002126:Calcium Hydroxide