title: Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation.
abstract: The structures of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1, were elucidated by spectroscopic studies, including various NMR experiments. Pentacecilides have a common pentacyclic meroterpene core, which contains an aromatic ring and a delta-lactone ring.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kitasato University, Shirokane, Tokyo, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Omura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tomoda
mesh_terms: D000818:Animals; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D008970:Molecular Weight; D012717:Sesquiterpenes / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000960:Hypolipidemic Agents; D012717:Sesquiterpenes; C544291:pentacecilide A; C544292:pentacecilide B; C544290:pentacecilide C