title: Tumours and tumour-like lesions of the hip in the paediatric age: a review of the Rizzoli experience.
abstract: Bone tumours and tumour-like lesions of the hip in children are rare. Signs and symptoms of these tumours are generally nonspecific. Delay of diagnosis is not uncommon. A high index of suspicion in young patients presenting with persistent pain and without history of trauma, that is unresolved with conservative therapy should prompt further investigation, including radiographs or computed tomography scan of the pelvis. In the experience of the Istituto Rizzoli, in patients less than 14 years (mean 9 years, ranged from 6 months to 14 years), 752 tumours and tumours-like lesions occurred in the pelvis or proximal femur, involving the hip. Tumour-like lesions accounted for 322 cases (simple bone cyst in 255, eosinophilic granuloma in 43, aneurismal bone cyst in 34), benign tumours for 340 cases (osteoid osteoma in 229, fibrous dysplasia in 63, exostosis in 48) and malignant tumours for 80 cases (Ewing's sarcoma in 53 and osteosarcoma in 27). The epidemiology, pathology, clinical presentation, and radiograph findings are discussed for each of these tumours.Treatment of these tumours differs from observation or minimally invasive treatment for most pseudotumoural lesions, intralesional excision or termoablation for benign bone tumours and wide resection for malignant bone tumours. In this latter group, chemotherapy is required and often administered pre- and postoperatively.
authors.affiliation: Department of Orthopedics, University of Bologna, Istituto Ortopedico Rizzoli, Via Pupilli, 1, Bologna 40136, Italy. pietro.ruggieri@ior.it
authors.forename: P
authors.initials: P
authors.lastname: Ruggieri
authors.forename: A
authors.initials: A
authors.lastname: Angelini
authors.forename: M
authors.initials: M
authors.lastname: Montalti
authors.forename: E
authors.initials: E
authors.lastname: Pala
authors.forename: T
authors.initials: T
authors.lastname: Calabrò
authors.forename: G
authors.initials: G
authors.lastname: Ussia
authors.forename: C N
authors.initials: CN
authors.lastname: Abati
authors.forename: M
authors.initials: M
authors.lastname: Mercuri
mesh_terms: D000293:Adolescent; D017824:Bone Cysts, Aneurysmal / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D004803:Eosinophilic Granuloma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D005096:Exostoses / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D005260:Female; D005266:Femoral Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D005358:Fibrous Dysplasia, Monostotic / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D006615:Hip; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008297:Male; D010017:Osteoma, Osteoid / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D010146:Pain; D012512:Sarcoma, Ewing / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy