[Under-evaluated extrahepatic manifestations of cholestasis].
Biliary stasis can occur in many different diseases. Pruritus, metabolic bone disease, deficiencies of fat-soluble vitamins, steatorrhea, hyperlipidemia and fatigue represent the major extra-hepatic manifestations of cholestatic liver disease that considerably affect the patient's quality of life. The present article reviews pathogenetic and clinical aspects of and current therapeutic approaches to extra-hepatic manifestations of cholestatic liver disease.
Prelipcean
Cristina Cijevschi
CC
Institutul de Gastroenterologie şi Hepatologie laşi.
Mihai
Cătălina
C
Gogălniceanu
P
P
Drug
V L
VL
Chirilă
N
N
D000837:Anion Exchange Resins / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D001651:Cholestasis, Extrahepatic / Q000150:complications* / Q000378:metabolism / Q000628:therapy; D004359:Drug Therapy, Combination; D005221:Fatigue / Q000209:etiology; D006464:Hemoperfusion; D006801:Humans; D006937:Hypercholesterolemia / Q000209:etiology; D006949:Hyperlipidemias / Q000209:etiology; D016031:Liver Transplantation; D008286:Malabsorption Syndromes / Q000209:etiology; D009292:Narcotic Antagonists / Q000627:therapeutic use; D010024:Osteoporosis / Q000209:etiology; D010956:Plasmapheresis; D011537:Pruritus / Q000209:etiology; D011788:Quality of Life; D045602:Steatorrhea / Q000209:etiology; D016896:Treatment Outcome; D014467:Ultraviolet Therapy; D014807:Vitamin D / Q000627:therapeutic use; D014815:Vitamins / Q000378:metabolism
D000837:Anion Exchange Resins; D009292:Narcotic Antagonists; D014815:Vitamins; D014807:Vitamin D; D002118:Calcium