title: Impact of energy loss coefficient on left ventricular mass regression in patients undergoing aortic valve replacement: preliminary observation.
abstract: BACKGROUND
  The purpose of this study was to evaluate the impact of Doppler-derived energy loss coefficient (ELCo) on the regression of left ventricular (LV) hypertrophy after aortic valve replacement (AVR) in patients with severe aortic stenosis.
  
  
  METHODS
  Twenty-four patients with severe aortic stenosis who underwent AVR with Carpentier-Edwards pericardial bioprosthetic valves (valve size 19 mm, n = 16; valve size 21 mm, n = 8) were examined. Within 12 months after AVR, follow-up echocardiography and Doppler measurements were performed. The effect of AVR was quantified on the basis of absolute and relative LV mass regression.
  
  
  RESULTS
  There were significant correlations between indexed ELCo and absolute (r = 0.50, P = .013) and relative (r = 0.48, P = .018) LV mass regression. The mean value of relative LV mass regression was 25%, and a cutoff value of 0.9 cm2/m2 for indexed ELCo could detect patients with relative LV mass regression > 25% after AVR with sensitivity of 71% and specificity of 100%.
  
  
  CONCLUSIONS
  ELCo, which can be calculated noninvasively from echocardiography, might be an important value to relate to LV mass regression in patients after AVR.
authors.affiliation: Department of Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
authors.forename: Teruyoshi
authors.initials: T
authors.lastname: Kume
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okura
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kawamoto
authors.forename: Nozomi
authors.initials: N
authors.lastname: Watanabe
authors.forename: Yoji
authors.initials: Y
authors.lastname: Neishi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hayashida
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tanemoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshida
mesh_terms: D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery*; D008297:Male; D011379:Prognosis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D014463:Ultrasonography