title: Fine needle aspiration cytology of palatine tonsils: a study of 112 consecutive adult tonsillectomies.
abstract: OBJECTIVE
  To study fine needle aspiration cytology (FNAC) findings of tonsillar lesions with histological controls and to assess its role in the diagnostic evaluation of tonsillectomy specimens.
  
  
  METHODS
  This study consisted of 112 cases that required tonsillectomy, comprising 55 (49.1%) men and 57 (50.9%) women. The ages ranged between 20 and 62 years. The clinical diagnosis in 101 cases was chronic tonsillitis, whereas 11 were suspected of neoplasia. FNAC was performed before tonsillectomy under general or local anaesthesia or on fresh specimens using a 21-G needle. The smears were stained using Wright-Giemsa and Papanicolaou methods. Histological examination was carried out on surgical specimens of all cases and, when required, immunohistochemistry was performed on histological sections. The diagnostic outcomes between FNAC and surgical biopsy were compared.
  
  
  RESULTS
  In this study, 106 cases were diagnosed as chronic tonsillitis/follicular hyperplasia, four cases as non-Hodgkin's lymphoma, one as Hodgkin's lymphoma and one as monophasic synovial sarcoma. All malignant cases were diagnosed by FNAC, but synovial sarcoma was incorrectly diagnosed as squamous cell carcinoma. Five cases clinically suspected of neoplasia were correctly diagnosed as chronic tonsillitis on cytology.
  
  
  CONCLUSIONS
  Tonsillar aspiration is a safe procedure and is useful in the evaluation of tonsillectomy specimens. However, ancillary tests on cytological material are often needed when neoplasia is suspected and would help clinical management and allow histological examination of cases diagnosed cytologically as lymphoma.
authors.affiliation: Department of Pathology, Shiraz Medical School, Shiraz, Iran.
authors.forename: M J
authors.initials: MJ
authors.lastname: Ashraf
authors.forename: N
authors.initials: N
authors.lastname: Azarpira
authors.forename: B
authors.initials: B
authors.lastname: Nowroozizadeh
authors.forename: M
authors.initials: M
authors.lastname: Shishegar
authors.forename: B
authors.initials: B
authors.lastname: Khademi
authors.forename: A
authors.initials: A
authors.lastname: Faramarzi
authors.forename: S B
authors.initials: SB
authors.lastname: Hashemi
authors.forename: A
authors.initials: A
authors.lastname: Hakimzadeh
authors.forename: E
authors.initials: E
authors.lastname: Abedi
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014066:Palatine Tonsil / Q000473:pathology*; D013584:Sarcoma, Synovial / Q000473:pathology; D014068:Tonsillectomy; D055815:Young Adult