title: Efficacy of composite allograft and demineralized bone matrix graft in treating tibial plateau fractures with bone loss.
abstract: Tibial plateau fractures with bone loss or significant comminution require grafting and stable fixation. We hypothesized a standardized protocol of internal fixation augmented with a mixture of demineralized bone matrix and corticocancellous allograft chips would result in high healing rates with minimal subsidence. Union was achieved in all 36 patients available for follow-up by a mean of 4.4 months. Mean range of motion was 2 degrees to 120 degrees. One patient developed osteomyelitis. Subsidence ranging from 2.5 to 5.7 mm occurred in 4 patients (11%). This treatment method provides sufficient structural integrity with a high union rate and a low complication rate.
authors.affiliation: Department of Orthopedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock St, Denver, CO 80204, USA.
authors.forename: Justin T
authors.initials: JT
authors.lastname: Newman
authors.forename: Wade R
authors.initials: WR
authors.lastname: Smith
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Ziran
authors.forename: Erik A
authors.initials: EA
authors.lastname: Hasenboehler
authors.forename: Philip F
authors.initials: PF
authors.lastname: Stahel
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Morgan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018775:Bone Demineralization Technique; D001857:Bone Matrix / Q000637:transplantation*; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000295:instrumentation* / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000150:complications / Q000601:surgery*; D013978:Tibial Fractures / Q000175:diagnosis* / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018786:Bone Substitutes