title: [Male hypogonadotropic hypogonadism (MHH) outpatient with testosterone deficiency syndrome: a case report].
abstract: A 59-year-old male was referred to our hospital with chief complaints of general fatigue and muscle stiffness of the shoulders. His hormonal data were total testosterone 0.05 ng/ml (normal: 2.01-7.5 ng/ml), free testosterone less than 0.6 pg/ml, leuteinizing hormone (LH) 1.1 mIU/ml (2.2-8.4 mIU/ml), follicle stimulating hormone (FSH) 2.4 mIU/ml (1.8-12 mIU/ml) and prolactin (PRL) 13.1 ng/ml (4.3-13.7 ng/ml). Though both his genital stage and pubic hair stage were Tanner V, his testis volume was 12 ml on the right and 10 ml on the left. A gonadotropin releasing hormone (GnRH) stimulation test revealed low responses of LH and FSH. Magnetic resonance imaging of the head revealed pituitary tumor (15 mm). Our diagnosis was acquired hypogonadtropic-hypogonadism-related pituitary tumor. Transsphenoidal hypophysectomy was performed and pathological diagnosis revealed epidermoid cyst. Three months after the operation, his total testosterone was elevated to 1.17 ng/ml and his complaints were improved.
authors.affiliation: The department of Urology and Andrology, Kansai Medical University.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Gen
authors.initials: G
authors.lastname: Kawa
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Tadashi
authors.initials: T
authors.lastname: Matsuda
authors.forename: Akio
authors.initials: A
authors.lastname: Asai
mesh_terms: D004814:Epidermal Cyst / Q000150:complications; D006801:Humans; D007006:Hypogonadism / Q000209:etiology*; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications; D013577:Syndrome; D013739:Testosterone / Q000172:deficiency*
chemical_list: D013739:Testosterone