title: Determination of alpha-bisabolol and d-panthenol in cosmetic products by gas chromatography.
abstract: Synopsis alpha-bisaboloi and d-panthenol are used in many cosmetic preparations, respectively, for their anti-inflammatory and regenerating properties. Their quantitative determination was an important element of their evaluation in these emulsions. Their concentration has been determined by gas chromatographic techniques, using a flame ionization detector. In both cases, the internal standards have been chosen for their compatibility with the analysis of extracted substances. Owing to the complexity of the cosmetic formulations, a preliminary extraction of alpha-bisabolol and d-panthenol was necessary. For the two substances the preparative separation was based on a liquid-liquid extraction. After dissolving the emulsion in methanol and diluting it with an aqueous buffer solution alpha-bisabolol was then extracted by ethyl acetate and d-panthenol by ethyl formate.
authors.affiliation: Laboratoire de Pharmacochimie et, B.P. 97, Avenue de l'Université, 76803 Saint Etienne Rouvray Cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Andre
authors.forename: P
authors.initials: P
authors.lastname: Verite
authors.forename: R
authors.initials: R
authors.lastname: Duclos
authors.forename: A M
authors.initials: AM
authors.lastname: Orecchioni
authors.forename: F
authors.initials: F
authors.lastname: Failly