Rac and Rho driving tumor invasion: who's at the wheel?
Genome-wide analysis of regulators of Rho-family small GTPases has identified critical elements that control the morphology and invasive behavior of melanoma cells.
Symons
Marc
M
Center for Oncology and Cell Biology, The Feinstein Institute for Medical Research at North Shore-LIJ, Manhasset, NY 11030, USA. msymons@nshs.edu
Segall
Jeffrey E
JE
D000818:Animals; D048430:Cell Shape; D006801:Humans; D009361:Neoplasm Invasiveness / Q000473:pathology*; D010641:Phenotype; D020744:rac GTP-Binding Proteins / Q000378:metabolism*; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
D020744:rac GTP-Binding Proteins; D020741:rho GTP-Binding Proteins