title: Hand eczema and quality of life: a population-based study.
abstract: BACKGROUND
  Hand eczema is a common disease in the population and is of interest from a public health perspective. Health-related quality of life (HRQoL) is increasingly being measured in dermatology.
  
  
  OBJECTIVE
  To investigate HRQoL in relation to hand eczema in the general population.
  
  
  METHODS
  In the Public Health Survey of Stockholm County Council 2006, a questionnaire was sent to 57 009 randomly selected individuals aged 18-84 years. The response rate among persons of working age (18-64 years) was 58%. The questionnaire included a validated question concerning hand eczema and a generic instrument for measurement of HRQoL, the EQ-5D.
  
  
  RESULTS
  The proportion of individuals reporting problems was significantly larger among those with than without hand eczema in all five dimensions of the EQ-5D. Gender differences were found in some age subgroups. The EQ-5D index was lower for individuals with hand eczema than for those without, and on the same level as for psoriasis and asthma. Beta regression showed that the strongest confounding factors were low back pain, depression and hay fever/asthma.
  
  
  CONCLUSIONS
  HRQoL was negatively affected in individuals with hand eczema irrespective of age. With the EQ-5D instrument it is also possible to detect certain gender differences. The EQ-5D index for hand eczema was of the same size as for psoriasis and asthma, all common diseases with an impact on public health. It is of importance to acknowledge the influence of hand eczema on daily life, in order to give the patients good care.
authors.affiliation: Department of Medicine Solna, Karolinska Institutet, 17176 Stockholm, Sweden. cecilia.e.moberg@sll.se
authors.forename: C
authors.initials: C
authors.lastname: Moberg
authors.forename: M
authors.initials: M
authors.lastname: Alderling
authors.forename: B
authors.initials: B
authors.lastname: Meding
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D004485:Eczema / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006229:Hand Dermatoses / Q000453:epidemiology* / Q000523:psychology; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life / Q000523:psychology; D012737:Sex Factors; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology; D055815:Young Adult