Dye labelling of nucleosides.
Dye-labelled nucleosides were obtained in 30-79% (average 45%) yields by treating N-(4-arylazobenzoyl)-1H-benzotriazoles 3a-b with appropriate nucleosides. Similarly, 3a-b afforded dye-labelled threoninol conjugates in 55-89% (average 67%) yields. All novel products were characterized by NMR and elemental analysis.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
Khelashvili
Levan
L
Kovacs
Judit
J
Shanab
Karem
K
D000605:Amino Alcohols / Q000138:chemical synthesis / Q000737:chemistry*; D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002072:Butylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D004396:Coloring Agents / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry*; D013194:Staining and Labeling / Q000379:methods*; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry*
D000605:Amino Alcohols; D001391:Azo Compounds; D002072:Butylene Glycols; D004396:Coloring Agents; D009705:Nucleosides; D014230:Triazoles; C532652:threoninol; C012771:benzotriazole; C009850:azobenzene