title: Selective anion binding in water with use of a zinc(II) dipicolylamino functionalized diketopiperazine scaffold.
abstract: The design and synthesis of a diketopiperazine based anion receptor bearing two dipicolylamino arms complexed to zinc(II) ions is described. This receptor is readily prepared from the dipeptide precursor by a microwave-assisted intramolecular cyclization reaction. Upon addition of zinc(II), the receptor binds di- and triphosphate ions with high affinity and selectivity in aqueous solution, as determined by using a fluorescent indicator displacement assay.
authors.affiliation: School of Chemistry, The University of Sydney, 2006, NSW, Australia.
authors.forename: Jessica Veliscek
authors.initials: JV
authors.lastname: Carolan
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Butler
authors.forename: Katrina A
authors.initials: KA
authors.lastname: Jolliffe