Is it ethical to have a placebo arm in reperfusion trials in the 3- to 6-hour time window? Yes.
Grotta
James
J
Department of Neurology, University of Texas Medical School at Houston, Houston, TX 77030, USA. James.c.grotta@uth.tmc.edu
Barreto
Andrew
A
D000208:Acute Disease; D006801:Humans; D010919:Placebos; D016032:Randomized Controlled Trials as Topic / Q000941:ethics* / Q000379:methods; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000941:ethics*; D013997:Time Factors
D010919:Placebos