title: Current aspects of perioperative fluid handling in vascular surgery.
abstract: OBJECTIVE
  Perioperative fluid management influences patient outcome. Vascular surgery unites various surgical procedures, mainly with a high impact on patients who often have relevant preexisting illnesses. There are only scarce data on this specialty, forcing the clinician to extrapolate existing data when planning perioperative fluid management. This review aims to summarize the underlying facts.
  
  
  RESULTS
  Perioperative insensible perspiration does not exceed 1 ml/kg per hour. A third space shift does not exist; therefore, its primary substitution is erroneous. Rather, a crystalloid fluid excess causes a tremendous shift towards the interstitial space. Colloidal volume effects are context sensitive, that is, only their use as a substitute when blood or plasma loss occurs leads to maintenance within the circulatory space. Colloidal hypervolaemia and surgical trauma both have the potential to deteriorate the vascular barrier, leading to plasma loss into the interstitial space. Current perioperative fluid therapy should aim to maintain normovolaemia of the individual body fluid compartments as far as possible. This might be achieved by combining a protocol-based replacement of extracellular losses (urinary output plus insensible perspiration) with isotonic balanced crystalloids and blood volume optimization using isooncotic colloids.
  
  
  CONCLUSIONS
  The basis of fluid therapy in vascular surgery is a careful differential indication of the respective classes of preparations. A goal-directed approach might help to avoid hypovolaemia.
authors.affiliation: Clinic of Anaesthesiology, Ludwig Maximilians University of Munich, Munich, Germany. matthias.jacob@med.uni-muenchen.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Jacob
authors.forename: Daniel
authors.initials: D
authors.lastname: Chappell
authors.forename: Markus W
authors.initials: MW
authors.lastname: Hollmann
mesh_terms: D003102:Colloids / Q000627:therapeutic use; D000077324:Crystalloid Solutions; D005440:Fluid Therapy; D006801:Humans; D007552:Isotonic Solutions / Q000627:therapeutic use; D007668:Kidney / Q000503:physiopathology; D019990:Perioperative Care; D010952:Plasma Substitutes / Q000627:therapeutic use; D014656:Vascular Surgical Procedures; D014870:Water Loss, Insensible
chemical_list: D003102:Colloids; D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D010952:Plasma Substitutes