Role of excited states in low-energy electron (LEE) induced strand breaks in DNA model systems: influence of aqueous environment.
Low-energy electrons (LEEs) interact with a DNA model system to create a variety of excited states. In the gas phase, dissociative (sigma*) states are accessible by LEEs with energy <4 eV (see picture) and cause facile strand breaks through a dissociative electron attachment mechanism. However, under solvation these dissociative (sigma*) states are blue-shifted and are less accessible to LEEs.
Kumar
Anil
A
Department of Chemistry, Oakland University, Rochester, MI 48309, USA.
Sevilla
Michael D
MD
D004247:DNA / Q000737:chemistry*; D053960:DNA Breaks; D004583:Electrons; D013816:Thermodynamics; D014867:Water / Q000737:chemistry*
D014867:Water; D004247:DNA