[Tuberculosis after renal transplantation].
Renal transplant recipients carry a relatively high risk of developing tuberculosis (TB). In most cases, active TB is the result of reactivation of a latent infection and is located in the lungs. In these patients, clinical presentation of TB can often be atypical and there is a high risk of dissemination and high mortality rates. Therefore, the use of invasive procedures for proper diagnosis is recommended, as well as anti-tuberculosis therapy instituted whenever there is a strong suspicion of TB on clinical grounds, even without microbiological evidence. The treatment of active TB in renal transplant recipients should be the same as in the general population. To avoid graft rejection, blood levels of calcineurin inhibitors should be monitored closely. Prophylaxis is recommended for high-risk patients.
Korzeniewska
Anna
A
Klinika Pulmonologii i Nowotworów Płuc Akademii Medycznej we Wrocławiu.
Dyła
Tomasz
T
Kosacka
Monika
M
Jankowska
Renata
R
D000995:Antitubercular Agents / Q000627:therapeutic use; D014943:Global Health; D006084:Graft Rejection / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D011379:Prognosis; D012307:Risk Factors; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000209:etiology; D014401:Tuberculosis, Urogenital / Q000453:epidemiology / Q000209:etiology
D000995:Antitubercular Agents; D007166:Immunosuppressive Agents