title: Pulse oximetric thresholds for tonsillectomy and adenotomy in children: significance of 1-2% decline in oxyhemoglobin saturation.
abstract: OBJECTIVE
  We aimed to establish optimal overnight pulse oximetric thresholds for determining the indication of tonsillectomy and adenotomy (TA) in children by revising the definition of 'desaturation'.
  
  
  METHODS
  One hundred and thirty four children scheduled for TA (TA group, 5.3 +/- 1.4 years old) and 112 otherwise healthy children scheduled for elective minor surgery (control group, 5.4 +/- 1.5 years old) were enrolled into this prospective study. Data were recorded and stored every 10 s using Nellcor N-395. Desaturation/resaturation events were defined as x% change (x = 1-4) of SpO2 (oxyhemoglobin saturation by pulse oximetry) in 10 s. The desaturation/resaturation indices were calculated as events per hour of total sleeping time. For each index, a wide range of temporary thresholds was set. The optimal thresholds for TA were the ones that maximized the weighted average for sensitivity, specificity (based on whether the index improved or not after TA), and the percentage of the control children whose indices were below the threshold.
  
  
  RESULTS
  For all the indices, the optimal thresholds that fulfilled the above condition were determined. Compared with the x = 3-4% results, the application of x = 1-2% approximately doubled the TA patients whose preoperative 'positive' indices improved after TA, with the weighted averages of 84.3-92.3% as described above.
  
  
  CONCLUSIONS
  By defining desaturation/resaturation as a 1-2% change in SpO2 from the preceding value, children with adenotonsillar hypertrophy whose pulse oximetric indices are expected to improve after TA can be detected by pulse oximetry with relatively high sensitivity and specificity.
authors.affiliation: Department of Anesthesiology and Intensive care medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. miyamoto@anes.med.osaka-u.ac.jp
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: Keiko
authors.initials: K
authors.lastname: Kinouchi
authors.forename: Mitsuhito
authors.initials: M
authors.lastname: Sano
authors.forename: Naoya
authors.initials: N
authors.lastname: Iguchi
authors.forename: Rie
authors.initials: R
authors.lastname: Ono
authors.forename: Seiji
authors.initials: S
authors.lastname: Kitamura
authors.forename: Takashi
authors.initials: T
authors.lastname: Mashimo
mesh_terms: D000233:Adenoidectomy / Q000379:methods*; D000234:Adenoids / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D017558:Elective Surgical Procedures / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods / Q000706:statistics & numerical data; D010092:Oximetry / Q000379:methods* / Q000706:statistics & numerical data; D010108:Oxyhemoglobins / Q000032:analysis / Q000378:metabolism*; D014066:Palatine Tonsil / Q000473:pathology; D011184:Postoperative Period; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods / Q000706:statistics & numerical data; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D014068:Tonsillectomy / Q000379:methods*
chemical_list: D010108:Oxyhemoglobins