B cell multitasking is required to control nematode infection.
In this issue of Immunity, Wojciechowski et al. (2009) demonstrate that in addition to producing antibodies, B cells play pivotal roles in specific-antigen presentation and cytokine production for optimal T helper 2 responses required for protection against Heligmosomoides polygyrus.
Alugupalli
Kishore R
KR
Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107, USA. kishore.alugupalli@mail.jci.tju.edu
Abraham
David
D
D000818:Animals; D017951:Antigen Presentation; D001402:B-Lymphocytes / Q000276:immunology / Q000502:physiology*; D016207:Cytokines / Q000378:metabolism; D051379:Mice; D009351:Nematospiroides dubius / Q000502:physiology*; D017206:Strongylida Infections / Q000276:immunology* / Q000517:prevention & control*
D016207:Cytokines