title: [A case of resection of synchronous multiple liver metastases from colorectal cancer after FOLFOX chemotherapy].
abstract: A 41-year-old man with multiple liver metastases from sigmoid colon cancer received a radical resection of the original tumor and 16 courses of weekly high-dose 5-FU(WHF)chemotherapy via hepatic arterial reservoir. The metastatic lesions showed stable disease(SD), and systemic chemotherapy by mFOLFOX6 was begun via CV port. After 14 courses of mFOLFOX4, abdominal CT revealed liver metastases were remarkably reduced in size. Hepatic resection of lateral segment and radio frequency ablation(RFA)for S6 were enforced, and the patient was uneventfully discharged. Pathological findings of lateral segment revealed no residual cancer cells, indicating that the histological effect of mFOLFOX6 was Grade 3.
authors.affiliation: Dept. of Surgery, National Hospital Organization Fukuyama Medical Center.
authors.forename: Shinya
authors.initials: S
authors.lastname: Otsuka
authors.forename: Masaru
authors.initials: M
authors.lastname: Inagaki
authors.forename: Manabu
authors.initials: M
authors.lastname: Nishie
authors.forename: Ryousuke
authors.initials: R
authors.lastname: Hamano
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Tokunaga
authors.forename: Kenji
authors.initials: K
authors.lastname: Takahashi
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Tsunemitsu
authors.forename: Kazuya
authors.initials: K
authors.lastname: Miyoshi
authors.forename: Masahiko
authors.initials: M
authors.lastname: Takahashi
authors.forename: Toshihide
authors.initials: T
authors.lastname: Oosaki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Iwagaki
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008297:Male; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012074:Remission Induction; D014057:Tomography, X-Ray Computed
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil