title: Sharing data between LSDBs and central repositories.
abstract: Several Locus-Specific DataBases (LSDBs) have recently been approached by larger, more general data repositories (including NCBI and UCSC) with the request to share the DNA variant data they have collected. Within the Human Genome Variation Society (HGVS) a document was generated summarizing the issues related to these requests. The document has been circulated in the HGVS/LSDB community and was discussed extensively. Here we summarize these discussions and present the concluded recommendations for LSDB data sharing with central repositories.
authors.affiliation: Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands. ddunnen@lumc.nl
authors.forename: Johan T
authors.initials: JT
authors.lastname: den Dunnen
authors.forename: Rolf H
authors.initials: RH
authors.lastname: Sijmons
authors.forename: Paal S
authors.initials: PS
authors.lastname: Andersen
authors.forename: Mauno
authors.initials: M
authors.lastname: Vihinen
authors.forename: Jacques S
authors.initials: JS
authors.lastname: Beckmann
authors.forename: Sandro
authors.initials: S
authors.lastname: Rossetti
authors.forename: C Conover
authors.initials: CC
authors.lastname: Talbot
authors.forename: Ross C
authors.initials: RC
authors.lastname: Hardison
authors.forename: Sue
authors.initials: S
authors.lastname: Povey
authors.forename: Richard G H
authors.initials: RG
authors.lastname: Cotton
mesh_terms: D019295:Computational Biology / Q000379:methods / Q000592:standards; D030541:Databases, Genetic; D014644:Genetic Variation; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D033181:Information Dissemination; D009154:Mutation; D020641:Polymorphism, Single Nucleotide