Neurotrophins and neuronal migration in the developing rodent brain.
Neurotrophins are known to be key regulators of neuronal survival, differentiation, function and plasticity in the developing and adult rodent brain. A novel role for neurotrophins has been emerging from recent research, that of motogenic and chemoattractant factors for several populations of migrating neuronal precursors in the developing mouse brain. The aim of the present article is to summarize and discuss the studies that have contributed to the existing body of evidence.
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Eleni
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Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1072, USA.
D000818:Animals; D001921:Brain / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D002465:Cell Movement / Q000187:drug effects / Q000502:physiology*; D049109:Cell Proliferation; D006224:Cricetinae; D051379:Mice; D009414:Nerve Growth Factors / Q000145:classification / Q000494:pharmacology / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D012377:Rodentia
D009414:Nerve Growth Factors