Churg-Strauss syndrome in a child with IgA nephropathy.
Churg-Strauss syndrome (CSS) is a rare systemic vasculitis associated with asthma and eosinophilia. Withdrawal of corticosteroids in asthmatic patients is known to be a powerful trigger for the development of CSS. Renal involvement in patients with CSS is commonly manifested as antineutrophil cytoplasm antibody-associated necrotizing crescentic glomerulonephritis, however, concomitant CSS and the nephrotic syndrome or IgA nephropathy are rare. We report a 12-year-old boy with CSS associated with IgA nephropathy that developed while tapering oral steroids. The patient had a history of the nephrotic syndrome and asthma.
Yim
H E
HE
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea.
Yoo
K H
KH
Won
N H
NH
Hong
Y S
YS
Lee
J W
JW
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000982:Antipruritics / Q000008:administration & dosage; D002648:Child; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000188:drug therapy*; D016572:Cyclosporine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005922:Glomerulonephritis, IGA / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007665:Ketotifen / Q000008:administration & dosage; D008297:Male; D011282:Pregnenediones / Q000008:administration & dosage
D000305:Adrenal Cortex Hormones; D000982:Antipruritics; D007166:Immunosuppressive Agents; D011282:Pregnenediones; D016572:Cyclosporine; C021988:deflazacort; D007665:Ketotifen