p53 protein expression in skin with different levels of photoaging.
In non-melanoma skin cancer, keratinocytes show marked p53 protein expression. Considering photoaging as a background for skin cancer, p53 protein expression by immunohistochemistry was evaluated in normal skin with different levels of photoaging. The difference in p53 expression between mild and severe levels of photoaging was not statistically significant (P=0.169).
de Castro
Inês Alencar
IA
Pós-Graduação em Medicina, Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. inesdecastro2007@terra.com.br
Schütz
Larissa
L
Capp
Edison
E
Cartell
André
A
Meurer
Luise
L
Bakos
Lucio
L
D000328:Adult; D000375:Aging / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012867:Skin / Q000378:metabolism* / Q000528:radiation effects*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
D016159:Tumor Suppressor Protein p53