title: Blink reflex recovery in central and peripherally originated movement disorders of the cranio-cervical area: a comparative study.
abstract: BACKGROUND
  Previous studies have shown that enhancement of blink reflex (BR) excitability exists in various movement disorders, notably those involving the cranio-cervical area. In this study the BR recovery curve of the late component (R2) and R2 area was evaluated to determine what changes occur under different conditions and the significance of these changes.
  
  
  METHODS
  The recovery curve of the blink reflex (BR) was studied in patients with hemifacial spasm (HFS), post-facial syndrome (PFS), blepharospasm (BS), segmental cranio-cervical dystonia (SD), cervical dystonia without BS (CD), and healthy control subjects. Following initial comparisons between six groups where the increased excitability observed in BS, SD and CD were assumed to be of central origin and that of HFS and PFS of peripheral origin; two additional groups were established and compared in terms of recovery times.
  
  
  RESULTS
  Recovery values of 200, 400, 600, 800, 1000 ms and grades for all groups were significantly different when compared to the control group. The most significant difference observed between the groups was at 200 msn and the smallest at 800 msn interstimuli intervals. The subjects within the group referred to as the 'central origined group' recovered faster than those in the 'peripherally origined group' although no statistical difference was found between the two groups at stimulus interval.
  
  
  CONCLUSIONS
  Our findings suggest that the excitability changes observed among the groups can be attributed to a number of factors. Although the nature and anatomical substrate of the primary pathology involving the reflex cycle leads - to some extent - to differently enhanced excitability patterns, such differences were not considered statistically significant.
authors.affiliation: Department of Neurology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Yaman
authors.forename: S
authors.initials: S
authors.lastname: Sahin
authors.forename: M Erdemir
authors.initials: ME
authors.lastname: Kiziltan
mesh_terms: D000328:Adult; D001767:Blinking / Q000502:physiology*; D002490:Central Nervous System / Q000502:physiology; D020821:Dystonic Disorders / Q000503:physiopathology; D005260:Female; D019569:Hemifacial Spasm / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000503:physiopathology*; D017933:Peripheral Nervous System / Q000502:physiology; D020127:Recovery of Function / Q000502:physiology*; D014103:Torticollis / Q000503:physiopathology