title: Antibacterial activity and bonding ability of an adhesive incorporating an antibacterial monomer DMAE-CB.
abstract: This study evaluated the antibacterial effect and microtensile bond strength of a resin-based adhesive containing an antibacterial monomer DMAE-CB (methacryloxylethyl cetyl dimethyl ammonium chloride). Cured specimens of 1, 2, and 3% DMAE-CB-containing Single Bond 2 (crosslinking monomer: Bis-GMA, dimethacrylates; functional monomer: HEMA) were prepared, and their antibacterial effects on Streptococcus mutans ATCC 25175 were investigated. Antibacterial property after 0, 30, 90, and 180 days of aging was also tested. Bonding ability of the experimental adhesive incorporating 3% DMAE-CB was evaluated by microtensile bond strength test. The cured experimental adhesive exhibited an inhibitory effect on S. mutans growth, and the adhesive containing 3% DMAE-CB showed higher antibacterial efficiency compared with those incorporating 1 or 2% anibacterial monomer. Antibacterial activities of the specimens lasted for at least 180 days. Microtensile bond strength test revealed that the bonding ability of the experimental adhesive was not significantly adversely affected by the incorporation of DMAE-CB. Therefore, dental adhesives with strong and long-lasting bacteriostatic property could be achieved by incorporating DMAE-CB without negatively influencing bonding ability.
authors.affiliation: Department of Stomatology, Kunming General Hospital of PLA, Kunming 650032, China.
authors.forename: Yu-Hong
authors.initials: YH
authors.lastname: Xiao
authors.forename: Sai
authors.initials: S
authors.lastname: Ma
authors.forename: Ji-Hua
authors.initials: JH
authors.lastname: Chen
authors.forename: Zhi-Guo
authors.initials: ZG
authors.lastname: Chai
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000268:Adhesiveness; D000269:Adhesives / Q000737:chemistry; D000890:Anti-Infective Agents / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D001840:Dental Bonding; D017220:Dentin-Bonding Agents / Q000737:chemistry; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning / Q000379:methods; D008956:Models, Chemical; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013295:Streptococcus mutans / Q000378:metabolism*; D013718:Tensile Strength; D013997:Time Factors
chemical_list: D000269:Adhesives; D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D000644:Quaternary Ammonium Compounds; C540902:methacryloxylethyl cetyl dimethyl ammonium