title: Tension-type headache.
abstract: The substantial societal and individual burdens associated with tension-type headache (TTH) constitute a previously overlooked major public health issue. TTH is prevalent, affecting up to 78% of the general population, and 3% suffer from chronic TTH. Pericranial myofascial nociception probably is important for the pathophysiology of episodic TTH, whereas sensitization of central nociceptive pathways seems responsible for the conversion of episodic to chronic TTH. Headache-related disability usually can be reduced by identification of trigger factors combined with nonpharmacologic and pharmacologic treatments, but effective treatment modalities are lacking. Benefits can be gained by development of specific and effective treatment strategies.
authors.affiliation: Danish Headache Center, Department of Neurology, University of Copenhagen, Glostrup Hospital, DK-2600 Glostrup, Denmark. larben01@glo.regionh.dk
authors.forename: Lars
authors.initials: L
authors.lastname: Bendtsen
authors.forename: Rigmor
authors.initials: R
authors.lastname: Jensen
mesh_terms: D006801:Humans; D009434:Neural Pathways / Q000503:physiopathology*; D010147:Pain Measurement / Q000379:methods; D011379:Prognosis; D018781:Tension-Type Headache / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome