Aspergillus alabamensis, a new clinically relevant species in the section Terrei.
Phylogenetic analyses of sequences generated from portions of three genes coding for the proteins enolase (enoA), beta-tubulin (benA), and calmodulin (calM) of a large number of isolates within the section Terrei, genus Aspergillus, revealed the presence of a new cryptic species within this section, Aspergillus alabamensis. Most members of this new cryptic species were recovered as colonizing isolates from immunocompetent patient populations, had decreased in vitro susceptibilities to the antifungal drug amphotericin B, and were morphologically similar to but genetically distinct from Aspergillus terreus isolates.
Balajee
S Arunmozhi
SA
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. fir3@cdc.gov
Baddley
John W
JW
Peterson
Stephen W
SW
Nickle
David
D
Varga
János
J
Boey
Angeline
A
Lass-Flörl
Cornelia
C
Frisvad
Jens C
JC
Samson
Robert A
RA
D001228:Aspergillosis / Q000382:microbiology*; D001230:Aspergillus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D002147:Calmodulin / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D016533:Mycological Typing Techniques; D010751:Phosphopyruvate Hydratase / Q000235:genetics; D010802:Phylogeny; D014404:Tubulin / Q000235:genetics
D002147:Calmodulin; D005656:Fungal Proteins; D014404:Tubulin; D010751:Phosphopyruvate Hydratase