Acute abdomen as initial presentation of gestational choriocarcinoma.
Choriocarcinoma is the most malignant tumor of gestational trophoblastic neoplasia. Choriocarcinoma presenting as postpartum hemorrhage and spontaneous uterine perforation with intra-abdominal hemorrhage is very rare. We present a 29-year-old woman with spontaneous uterine rupture due to choriocarcinoma following a live birth pregnancy. The long time interval (2 years) between the previous live birth pregnancy and the diagnosis of the disease, the acute onset of the disease by uterine rupture as the first symptom and the negative urine hCG test are presented and discussed in this case report.
Liberis
Vassilios
V
Department of Obstetrics and Gynecology, School of Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Bouchlariotou
Sofia
S
Ammari
Alexandros
A
Psillaki
Afroditi
A
Ntatidou
Maritsa
M
Sivridis
Efthimios
E
Dislian
Valentina
V
Koutlaki
Nikoleta
N
D000006:Abdomen, Acute / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007044:Hysterectomy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014595:Uterine Perforation / Q000473:pathology / Q000601:surgery
D018997:Chorionic Gonadotropin, beta Subunit, Human