title: Design and evaluation of a probe for simultaneous EEG and near-infrared imaging of cortical activation.
abstract: We present a novel probe design which enables simultaneous electroencephalography (EEG) and near-infrared (NIR) optical imaging to be performed in a manner which is easy to apply, allows for optimum co-registration of the two forms of data and maximizes the number of sensors which can be applied to a given area. Our probe design is evaluated using a dual-modality, tissue-mimicking phantom and by performing a simple functional activation study of the human motor cortex. We successfully acquired NIR optical and EEG data simultaneously for both our phantom and our human motor cortex experiments, clearly demonstrating the effectiveness and suitability of our 'opto-electrode'.
authors.affiliation: Department of Medical Physics & Bioengineering, University College London, London WC1E 6BT, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: Cooper
authors.forename: N L
authors.initials: NL
authors.lastname: Everdell
authors.forename: L C
authors.initials: LC
authors.lastname: Enfield
authors.forename: A P
authors.initials: AP
authors.lastname: Gibson
authors.forename: Alan
authors.initials: A
authors.lastname: Worley
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Hebden
mesh_terms: D004566:Electrodes; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D007259:Infrared Rays; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D055100:Optical Fibers; D019047:Phantoms, Imaging; D018511:Systems Integration; D013997:Time Factors; D055815:Young Adult