Irinotecan toxicity: genes or intestinal microflora?
Brandi
G
G
de Rosa
F
F
Biasco
G
G
D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D002166:Camptothecin / Q000009:adverse effects / Q000031:analogs & derivatives*; D051544:Cytochrome P-450 CYP3A / Q000235:genetics; D014453:Glucuronosyltransferase / Q000235:genetics*; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D000077146:Irinotecan; D000099148:UGT1A1 Enzyme
D000972:Antineoplastic Agents, Phytogenic; D002166:Camptothecin; D051544:Cytochrome P-450 CYP3A; D014453:Glucuronosyltransferase; D000077146:Irinotecan; D000099148:UGT1A1 Enzyme; C510163:CYP3A4 protein, human