Primary cystic germinoma originating from the midbrain.
A primary intracranial germinoma that involves the midbrain is rare. We describe an unusual case of primary cystic germinoma originating from the midbrain. A 29-year-old man presented with diplopia, and his MRI showed a cystic, ring-like enhanced lesion in the thalamo-mesencephalic junction. Open biopsy was performed and the diagnosis of germinoma was based upon the histopathological findings. Following chemotherapy and radiotherapy, the symptoms improved and the tumor disappeared. We propose that primary intracranial germinoma should be included in the differential diagnosis of midbrain tumors, because early diagnosis and appropriate treatment for midbrain germinoma improves clinical outcome.
Maruya
Jun
J
Department of Neurosurgery, Akita Red Cross Hospital, 222-1 Nawashirosawa, Saruta, Kamikitate, Akita 010-1495, Japan. jmaruya@archosp-1998.com
Narita
Eriko
E
Nishimaki
Keiichi
K
Heianna
Joichi
J
Miyauchi
Takaharu
T
Minakawa
Takashi
T
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001706:Biopsy; D020295:Brain Stem Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D016190:Carboplatin / Q000008:administration & dosage; D020863:Central Nervous System Cysts / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D004172:Diplopia / Q000209:etiology; D005047:Etoposide / Q000008:administration & dosage; D018237:Germinoma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000473:pathology*; D011878:Radiotherapy; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D005047:Etoposide; D016190:Carboplatin