title: Inguinal hernia repair with porcine small intestine submucosa: 3-year follow-up results of a randomized controlled trial of Lichtenstein's repair with polypropylene mesh versus Surgisis Inguinal Hernia Matrix.
abstract: BACKGROUND
  The aim of this study was to evaluate the safety and efficacy of Lichtenstein's hernioplasty using Surgisis Inguinal Hernia Matrix (SIHM; Cook, Bloomington, Indiana) compared with polypropylene (PP; Angiologica, Pavia, Italy).
  
  
  METHODS
  This was a prospective, randomized, double-blind trial comparing Lichtenstein's inguinal hernioplasty using SIHM versus PP.
  
  
  RESULTS
  Seventy male patients underwent Lichtenstein's hernioplasty (n = 35 in the SIHM group and n = 35 in the PP group). At 3 years after surgery, there were 2 deaths (5.7%) in the PP group and 1 death (2.9%) in the SIHM group (not significant [NS]). Although the study was underpowered to evaluate the recurrence rate, only 1 recurrence (2.9%) was seen in the PP group (NS). Although a significant decrease in postsurgical pain incidence was never observed among patients in the SIHM group, a significantly lower degree of pain was detected at rest and on coughing at 1, 3, and 6 months and on movement at 1, 3, and 6 months and 1, 2, and 3 years. A significant decrease in postsurgical incidence and degree of discomfort when coughing and moving were observed among patients in the SIHM group at 3 and 6 months and at 1, 2, and 3 years after surgery.
  
  
  CONCLUSIONS
  SIHM hernioplasty seems to be a safe and effective procedure.
authors.affiliation: Unit of General, Emergency and Transplant Surgery, St. Orsola-Malpighi University Hospital, Bologna, Italy. luca.ansaloni@aosp.bo.it
authors.forename: Luca
authors.initials: L
authors.lastname: Ansaloni
authors.forename: Fausto
authors.initials: F
authors.lastname: Catena
authors.forename: Federico
authors.initials: F
authors.lastname: Coccolini
authors.forename: Filippo
authors.initials: F
authors.lastname: Gazzotti
authors.forename: Luigi
authors.initials: L
authors.lastname: D'Alessandro
authors.forename: Antonio Daniele
authors.initials: AD
authors.lastname: Pinna
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D004311:Double-Blind Method; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000401:mortality / Q000601:surgery*; D006801:Humans; D015994:Incidence; D007421:Intestine, Small / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000453:epidemiology; D011126:Polypropylenes; D011446:Prospective Studies; D012008:Recurrence; D018709:Statistics, Nonparametric; D013526:Surgical Mesh; D013552:Swine; D016896:Treatment Outcome
chemical_list: D011126:Polypropylenes