Versatile, efficient derivatization of polysiloxanes via click technology.
Copper-catalyzed (click chemistry) or thermal 1,3-dipolar cycloadditions of molecular or polymeric azido-siloxanes with a broad range of alkynes (such as amino acids or carbohydrates) easily yield new conjugates that would be otherwise difficult, if not impossible, to prepare by traditional methodologies.
Gonzaga
Ferdinand
F
Department of Chemistry, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4M1, Canada. gonzaga@mcmaster.ca
Yu
Gilbert
G
Brook
Michael A
MA