title: Experimental use of labial mucosa free graft urinary conduit in the Mitrofanoff principle.
abstract: OBJECTIVE
  One method of treating urinary incontinence is to create a catheterizable and continent vesicostomy by the Mitrofanoff principle, based on the use of a conduit, which in the original method is the appendix. The authors present an experimental technique in which a continent vesicostomy is created by the Mitrofanoff principle, using a conduit made of a labial mucosa free graft.
  
  
  METHODS
  Six 30-day-old pigs underwent surgery to create a continent vesicostomy by the Mitrofanoff principle. A tube, made of labial mucosa free graft from the lower lip, was used. The labial mucosal conduit was anastomosed to the bladder mucosa. The tunnel was then prepared, part of which passed through the fibers of the right rectus muscle. The conduit was taken through the tunnel and anastomosed to the skin in the right iliac fossa.
  
  
  RESULTS
  Fifty days after the operation, the vesicostomy was continent, pervious, and easily catheterizable in 5 animals. In the sixth pig, the cystostomic tube did not graft successfully because it was infected.
  
  
  CONCLUSIONS
  A number of investigators have extrapolated Mitrofanoff method using the ileum, the ureter, or others. The use of a tube made by labial mucosa free graft is an easily performed technique, and as with the Mitrofanoff method, continence and easy catheterization are successfully achieved.
authors.affiliation: Unit of Pediatric Surgery, University of Sassari, 07100 Sassari, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Dessanti
authors.forename: Marco
authors.initials: M
authors.lastname: Iannuccelli
authors.forename: Eraldo
authors.initials: E
authors.lastname: Sanna-Passino
authors.forename: Gian Mario
authors.initials: GM
authors.lastname: Careddu
authors.forename: Paolo
authors.initials: P
authors.lastname: Cossu-Rocca
authors.forename: Maria Lucia
authors.initials: ML
authors.lastname: Manunta
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Dessanti
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D005260:Female; D005836:Genitalia, Female / Q000601:surgery; D009092:Mucous Membrane / Q000637:transplantation*; D013536:Suture Techniques; D013552:Swine; D001743:Urinary Bladder / Q000601:surgery*; D014546:Urinary Catheterization; D014549:Urinary Incontinence / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods*