title: Treatment of mediastinal fibrosis with mycophenolate mofetil.
abstract: We present the case of a 67-year-old male patient with mediastinal and retroperitoneal fibrosis. In Europe, this is a rare disease. Treatment was established to prevent complications due to strictures or compressions. Because of his diabetes, a therapy of low-dose prednisone combined with mycophenolate mofetil, known as steroid sparing agent, was applied. As a result, the radiological follow-up showed a marked decrease in the mediastinal and retroperitoneal masses.
authors.affiliation: Clinic and Polyclinic of Pneumology, Bern University Hospital, Bern, Switzerland.
authors.forename: Michael
authors.initials: M
authors.lastname: Witschi
authors.forename: Mathias
authors.initials: M
authors.lastname: Gugger
authors.forename: Laurent P
authors.initials: LP
authors.lastname: Nicod
mesh_terms: D000368:Aged; D005355:Fibrosis / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008477:Mediastinal Diseases / Q000188:drug therapy*; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid