title: [Anterior pituitary lobe atrophy as late complication of hemorrhagic fever with renal syndrome].
abstract: BACKGROUND
  Hemorrhagic fever with renal syndrome (HFRS) is acute infective multisystemic disease followed by febrility, hemorrhages and acute renal insufficiency. Bleeding in the anterior pituitary lobe leading to tissue necrosis occurs in acute stage of severe clinical forms of HFRS, while atrophy of the anterior pituitary lobe with diminution of the gland function occurs after recovery stage.
  
  
  METHODS
  We presented a patient with the development of chronic renal insufficiency and hypopituitarism as complication that had been diagnosed six years after Hantavirus infection. Magnetic resonance of the pituitary gland revealed atrophy and empty sella turcica.
  
  
  CONCLUSIONS
  Regarding frequency of this viral infection and its endemic character in some parts of our country partial and/or complete loss of pituitary function should be considered during the late stage of HFRS.
authors.affiliation: Vojnomedicinska akademija, Klinika za nefrologiju, Beograd.
authors.forename: Dragan
authors.initials: D
authors.lastname: Jovanović
authors.forename: Zoran
authors.initials: Z
authors.lastname: Kovacević
authors.forename: Tamara
authors.initials: T
authors.lastname: Dragović
authors.forename: Marijana
authors.initials: M
authors.lastname: Petrović
authors.forename: Jelena
authors.initials: J
authors.lastname: Tadić
mesh_terms: D000328:Adult; D001284:Atrophy; D004652:Empty Sella Syndrome / Q000209:etiology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D010903:Pituitary Gland, Anterior / Q000473:pathology*