[Intestinal motility disorders and visceral hypersensitivity in irritable bowel syndrome].
The pathophysiology of irritable bowel syndrome is complex, secondary to a dysregulation of the visceral neuromuscular system. Motor disorders and digestive hypersensitivity have been studied most: phasic and tonic abnormalities and visceral hypersensitivity associated with different types of receptors have been identified in patients with irritable bowel syndrome. For other patients, the combination of these disorders can explain abnormal physiological responses. Some records of various explorations are correlated with patient symptoms, such as pain, bloating, or bowel movement disorders. These sensorimotor disorders, probably not limited to the gut, are reviewed in this article.
Ropert
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A
Explorations Fonctionnelles Digestives, CHU Pontchaillou, rue H. Le Guillou, 35033 Rennes cedex, France. alain.ropert@chu-rennes.fr
Bouguen
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G
D015746:Abdominal Pain / Q000503:physiopathology; D003248:Constipation / Q000503:physiopathology; D003967:Diarrhea / Q000503:physiopathology; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000503:physiopathology*; D014781:Viscera / Q000294:innervation*