title: Lung volume reduction surgery and lung transplantation in chronic obstructive pulmonary disease.
abstract: Medical treatment of emphysema does not alter the natural progression of the disease. Surgical techniques are an attractive conceptual approach to treat hyperinflation in these patients. Lung volume reduction surgery and lung transplantation are appropriate therapeutic options for a selected population with emphysema. We will review the available evidence to support these approaches.
authors.affiliation: Albert Einstein Medical Center, Philadelphia, PA, USA.
authors.forename: Jorge I
authors.initials: JI
authors.lastname: Mora
authors.forename: Denis
authors.initials: D
authors.lastname: Hadjiliadis
mesh_terms: D002986:Clinical Trials as Topic; D003362:Cost-Benefit Analysis; D018450:Disease Progression; D019317:Evidence-Based Medicine; D020022:Genetic Predisposition to Disease; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects / Q000191:economics; D011013:Pneumonectomy / Q000009:adverse effects / Q000191:economics; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000235:genetics / Q000401:mortality / Q000601:surgery*; D011656:Pulmonary Emphysema / Q000209:etiology / Q000235:genetics / Q000401:mortality / Q000601:surgery*; D011788:Quality of Life; D012307:Risk Factors; D016896:Treatment Outcome; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications