title: The effect of intra-articular epinephrine lavage on blood loss following total knee arthroplasty.
abstract: The purpose of this study was to examine the effects of intra-articular epinephrine lavage on blood loss following total knee arthroplasty (TKA). Our retrospective study involved 189 patients who had primary cemented TKA by 1 of 2 surgeons. Surgeon 1 performed 41 procedures without and 53 with the epinephrine lavage. Surgeon 2 performed 41 procedures without and 54 with the epinephrine lavage. We compared calculated blood loss (CBL) for the patients in all 4 groups. We found no significant differences in CBL among the patients in the 4 patient groups. Our results show that an intra-articular epinephrine lavage does not affect blood loss after TKA.
authors.affiliation: Department of Orthopedic Surgery, William Beaumont Hospital, 3535 W 13 Mile Rd, Ste 744, Royal Oak, MI 48073, USA.
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Malone
authors.forename: Sean
authors.initials: S
authors.lastname: Matuszak
authors.forename: David
authors.initials: D
authors.lastname: Mayo
authors.forename: Perry
authors.initials: P
authors.lastname: Greene
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D015331:Cohort Studies; D004837:Epinephrine / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D007507:Therapeutic Irrigation; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*
chemical_list: D014662:Vasoconstrictor Agents; D004837:Epinephrine