title: CD90 Expression on human primary cells and elimination of contaminating fibroblasts from cell cultures.
abstract: Cluster Differentiation 90 (CD90) is a cell surface glycoprotein originally identified on mouse thymocytes. Although CD90 has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells, the knowledge about the levels of CD90 expression on different cell types, including human primary cells, is limited. The goal of this study was to identify CD90 as a human primary cell biomarker and to develop an efficient and reliable method for eliminating unwanted or contaminating fibroblasts from human primary cell cultures suitable for research pursuant to cell based therapy technologies.
authors.affiliation: Department of Cell Therapy, Lonza Walkersville, Inc., Walkersville, MD, 21793, USA, lynn.kisselbach@lonza.com.
authors.forename: Lynn
authors.initials: L
authors.lastname: Kisselbach
authors.forename: Michael
authors.initials: M
authors.lastname: Merges
authors.forename: Alexis
authors.initials: A
authors.lastname: Bossie
authors.forename: Ann
authors.initials: A
authors.lastname: Boyd