Flow-injection analysis for meloxicam based on tris(2,2'-bipyridine) ruthenium(II)-Ce(IV) chemiluminescent system.
It was found that meloxicam could enhance the chemiluminescence (CL) of the tris(2,2'-bipyridine) ruthenium(II)-Ce(IV) system in the medium of sulfate acid. Based on this phenomenon a new flow-injection system with chemiluminescent detection has been proposed for determination of meloxicam. Under optimum conditions, meloxicam had a good linear relationship with the CL intensity in the concentration range of 6.0 10(-4) to 1.0 microg/mL and the detection limit was 3.7 x 10(-4 )microg/mL. The proposed method was applied to detect meloxicam in tablets and a satisfactory recovery was obtained. The possible mechanism for this CL system is also discussed in this paper.
Ye
Huazhen
H
Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujan 350002, People's Republic of China.
Qiu
Bin
B
Chen
Jing
J
Lin
Jinming
J
Chen
Guonan
G
D015082:2,2'-Dipyridyl / Q000737:chemistry*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis / Q000737:chemistry; D002563:Cerium / Q000737:chemistry*; D017022:Flow Injection Analysis; D008163:Luminescent Measurements / Q000191:economics / Q000379:methods*; D000077239:Meloxicam; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013607:Tablets / Q000032:analysis / Q000737:chemistry; D013843:Thiazines / Q000032:analysis* / Q000737:chemistry; D013844:Thiazoles / Q000032:analysis* / Q000737:chemistry
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013607:Tablets; D013843:Thiazines; D013844:Thiazoles; D002563:Cerium; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D000077239:Meloxicam