Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2.
The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.
Hollmig
S Tyler
ST
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas Veterans Affairs Medical Center, Dallas, TX, USA.
Ariizumi
Kiyoshi
K
Cruz
Ponciano D
PD
D000818:Animals; D015703:Antigens, CD / Q000276:immunology; D002176:Candida albicans / Q000276:immunology*; D002177:Candidiasis / Q000276:immunology*; D037222:Collectins / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D037181:Lectins, C-Type / Q000276:immunology*; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins / Q000276:immunology; D008565:Membrane Proteins / Q000276:immunology*; D051379:Mice; D009419:Nerve Tissue Proteins / Q000276:immunology*; D011134:Polysaccharides / Q000276:immunology*; D011956:Receptors, Cell Surface / Q000276:immunology; D051192:Receptors, Pattern Recognition / Q000276:immunology; D000099181:Dectin-1
D015703:Antigens, CD; D037222:Collectins; D037181:Lectins, C-Type; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D011134:Polysaccharides; D011956:Receptors, Cell Surface; D051192:Receptors, Pattern Recognition; D000099181:Dectin-1; C121916:CD207 protein, human; C445340:dectin-2, mouse