Fertility intentions of HIV-1 infected and uninfected women in Malawi: a longitudinal study.
This study aimed to determine changes in fertility intentions of HIV-1 infected and uninfected reproductive age women in Blantyre, Malawi. Participants were asked about their fertility intentions at baseline and at 3-month visits for 1 year. Time-to-event statistical models were used to determine factors associated with changes in fertility intentions. Overall, 842 HIV uninfected and 844 HIV infected women were enrolled. The hazard of changing from wanting no more children at baseline to wanting more children at follow-up was 61% lower among HIV infected women compared to HIV uninfected women (P < 0.01) after adjusting for other factors, while HIV infected women were approximately 3 times more likely to change to wanting no more children. The overall pregnancy rate after 12 months was 14.9 per 100 person-years and did not differ among 102 HIV uninfected and 100 infected women who became pregnant. HIV infection is a significant predictor of fertility intentions over time.
Taulo
Frank
F
Department of Obstetrics and Gynecology, College of Medicine, University of Malawi, Private Bag 360 Chichiri, Blantyre, Malawi.
Berry
Mark
M
Tsui
Amy
A
Makanani
Bonus
B
Kafulafula
George
G
Li
Qing
Q
Nkhoma
Chiwawa
C
Kumwenda
Johnstone J
JJ
Kumwenda
Newton
N
Taha
Taha E
TE
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D005193:Family Planning Services; D005260:Female; D005298:Fertility; D015658:HIV Infections / Q000523:psychology*; D015497:HIV-1; D006801:Humans; D033182:Intention; D008137:Longitudinal Studies; D008295:Malawi; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D018873:Pregnancy Rate; D016896:Treatment Outcome; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage / Q000627:therapeutic use; D016585:Vaginosis, Bacterial / Q000188:drug therapy; D016387:Women's Health; D055815:Young Adult
D000900:Anti-Bacterial Agents; D014622:Vaginal Creams, Foams, and Jellies; D008795:Metronidazole