Photocyclization of tosylstilbenes as a key reaction in the preparation of an analogue of the antitumor agent CC-1065.
A photocyclization of tosylstilbenes in the presence of base is used as a key reaction in the synthesis of the CC-1065 analogue 5.
Neo
Ana G
AG
Departamento de Química Orgánica y Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Pérez
Antonio
A
López
Carmen
C
Castedo
Luis
L
Tojo
Gabriel
G
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D000080890:Duocarmycins; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010777:Photochemistry; D013267:Stilbenes / Q000138:chemical synthesis* / Q000737:chemistry*; D014105:Tosyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
D000470:Alkaloids; D000970:Antineoplastic Agents; D000080890:Duocarmycins; D007211:Indoles; D013267:Stilbenes; D014105:Tosyl Compounds; C018782:CC 1065