Metastatic uterine adenocarcinoma and hepatic lipomatosis in a llama (Lama glama).
A 6-year-old, female llama (Lama glama) presented with progressive anorexia and ascites. Postmortem examination revealed an infiltrative uterine adenocarcinoma with widespread metastases. The neoplasm completely replaced and infiltrated the myometrium of the uterine body and cervix and metastasized largely to the serosal surfaces of the peritoneal cavity. Histopathology identified a highly invasive growth of neoplastic cells in solid packets or tubular arrangements and marked fibroplasia. No bovine or llama papillomavirus DNA was detected intralesionally by polymerase chain reaction.
Klopfleisch
Robert
R
Freie Universität Berlin, College of Veterinary Medicine, Department of Veterinary Pathology, Robert-von-Ostertag-Str. 15, 14163 Berlin, Germany. klopfleisch.robert@vetmed.fu-berlin.de
van der Grinten
Elisabeth
E
Gruber
Achim D
AD
D000230:Adenocarcinoma / Q000556:secondary / Q000662:veterinary* / Q000821:virology; D000818:Animals; D002161:Camelids, New World; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D017809:Fatal Outcome; D005260:Female; D008068:Lipomatosis / Q000473:pathology / Q000662:veterinary*; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000662:veterinary* / Q000821:virology; D016133:Polymerase Chain Reaction / Q000662:veterinary; D014594:Uterine Neoplasms / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics
D004279:DNA, Viral; D014764:Viral Proteins