Light-activation of gene function in mammalian cells via ribozymes.
A ribozyme based gene control element enabled the spatio-temporal regulation of gene function in mammalian cell culture with light.
Young
Douglas D
DD
Department of Chemistry, North Carolina State University, Raleigh, NC 27695, USA.
Garner
R Aaron
RA
Yoder
Jeffrey A
JA
Deiters
Alexander
A
D002460:Cell Line; D015870:Gene Expression / Q000528:radiation effects*; D006801:Humans; D016337:RNA, Catalytic / Q000737:chemistry / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D014127:Toyocamycin / Q000737:chemistry* / Q000528:radiation effects; D014466:Ultraviolet Rays
D016337:RNA, Catalytic; D012333:RNA, Messenger; C427204:hammerhead ribozyme; D014127:Toyocamycin