title: Effect of epidural saline washout on regression of sensory and motor block after epidural anaesthesia with 2% lidocaine and fentanyl in elderly patients.
abstract: Seventy elderly males received lumbar epidural anaesthesia with 12 ml of 2% lidocaine containing fentanyl 50 mug. At the end of transurethral surgery, the washout group (n = 33) received an epidural bolus of 30 ml saline while the control group (n = 34) did not. Mean (SD) times to 1-grade (17.2 (11.9) vs 32.7 (11.3) min) and 2-grade regression (23.8 (12.2) vs 56.0 (23.9) min) of motor block, 3-dermatomal sensory regression (31.4 (11.6) vs 42.2 (14.4) min for cold and 30.8 (15.6) vs 40.6 (14.2) min for pinprick), and regression to S1 (57.7 (16.1) vs 76.2 (20.2) min for cold and 56.8 (17.3) vs 69.2 (16.2) min for pinprick) were significantly shorter in the washout group than the control group. There were no differences in postoperative pain scores and side effects between the two groups. We concluded that epidural washout facilitates regression of both motor and sensory block following epidural anaesthesia without reducing the postoperative analgesic benefit.
authors.affiliation: Department of Anaesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: E Y
authors.initials: EY
authors.lastname: Park
authors.forename: H K
authors.initials: HK
authors.lastname: Kil
authors.forename: W S
authors.initials: WS
authors.lastname: Park
authors.forename: N-H
authors.initials: NH
authors.lastname: Lee
authors.forename: J-Y
authors.initials: JY
authors.lastname: Hong
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000493:pharmacokinetics*; D000762:Anesthesia Recovery Period; D000767:Anesthesia, Epidural / Q000379:methods*; D000779:Anesthetics, Local / Q000493:pharmacokinetics*; D005283:Fentanyl / Q000493:pharmacokinetics*; D006801:Humans; D008012:Lidocaine / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000187:drug effects; D010149:Postoperative Pain; D011183:Postoperative Complications; D012677:Sensation / Q000187:drug effects; D016037:Single-Blind Method; D012965:Sodium Chloride / Q000008:administration & dosage*; D007507:Therapeutic Irrigation / Q000009:adverse effects / Q000379:methods
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D012965:Sodium Chloride; D008012:Lidocaine; D005283:Fentanyl