title: Psychopharmacologic management of opioid-dependent women during pregnancy.
abstract: Illicit drug use during pregnancy presents complex clinical challenges, including reducing drug use and treating psychiatric disorders. Pharmacologic treatment of psychiatric disorders in a pregnant woman requires an evaluation of the balance between potential clinical benefit and the risk of potential neonatal consequences. This study describes psychiatric symptoms in 111 opioid-dependent pregnant women and their prescribed psychotropic medications. Hypomania, generalized anxiety disorder and depression were the most common disorders for which psychiatric symptoms were endorsed. Over half of women studied were prescribed some form of psychoactive medication during pregnancy. Pharmacologic vs. non-pharmacologic treatment approaches in this patient population are discussed.
authors.affiliation: Vanderbilt University School of Medicine, Nashville, Tennessee, USA. peter.martin@vanderbilt.edu
authors.forename: Peter R
authors.initials: PR
authors.lastname: Martin
authors.forename: Amelia M
authors.initials: AM
authors.lastname: Arria
authors.forename: Gabriele
authors.initials: G
authors.lastname: Fischer
authors.forename: Karol
authors.initials: K
authors.lastname: Kaltenbach
authors.forename: Sarah H
authors.initials: SH
authors.lastname: Heil
authors.forename: Susan M
authors.initials: SM
authors.lastname: Stine
authors.forename: Mara G
authors.initials: MG
authors.lastname: Coyle
authors.forename: Peter
authors.initials: P
authors.lastname: Selby
authors.forename: Hendrée E
authors.initials: HE
authors.lastname: Jones
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000188:drug therapy; D001714:Bipolar Disorder / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology; D009293:Opioid-Related Disorders / Q000150:complications* / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs