Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp.
Notoamide E was identified to be a short-lived precursor in the biosynthesis of prenylated indole alkaloids in the mussel-derived Aspergillus sp. In addition, the feeding experiment of the (13)C-labeled notoamide E afforded structurally novel metabolites.
Tsukamoto
Sachiko
S
Graduate School of Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. sachiko@faculty.chiba-u.jp
Kato
Hikaru
H
Greshock
Thomas J
TJ
Hirota
Hiroshi
H
Ohta
Tomihisa
T
Williams
Robert M
RM
D000818:Animals; D001230:Aspergillus / Q000737:chemistry* / Q000378:metabolism; D049872:Bivalvia / Q000382:microbiology; D002247:Carbon Isotopes / Q000378:metabolism; D026121:Indole Alkaloids / Q000302:isolation & purification* / Q000378:metabolism; D054876:Prenylation
D002247:Carbon Isotopes; D026121:Indole Alkaloids; C541224:notoamide E