title: Primary intracranial leiomyosarcoma: a case report and review of the literature.
abstract: BACKGROUND
  Malignant tumours of the central nervous system (CNS) represent the second most common cancer type in the paediatric population of developed countries, and mortality caused by CNS tumours is the highest among paediatric cancers. Tumours of mesenchymal origin occurring either as primary or secondary lesions of the central nervous system are very rare in children. This paper describes the case of a 5-year-old non-immunocompromised male who presented with a right frontal primary intracranial leiomyosarcoma associated with large subdural collections.
  
  
  CONCLUSIONS
  Following surgical excision and adjuvant chemoradiotherapy, the patient has remained disease-free for 18 months. The literature is reviewed and the possible association of the chronic subdurals to the later development of the leiomyosarcoma explored.
authors.affiliation: Department of Neurosurgery, Southern General Hospital, Glasgow, UK. calan@doctors.org.uk
authors.forename: C S
authors.initials: CS
authors.lastname: Mathieson
authors.forename: E J
authors.initials: EJ
authors.lastname: St George
authors.forename: W
authors.initials: W
authors.lastname: Stewart
authors.forename: J
authors.initials: J
authors.lastname: Sastry
authors.forename: S
authors.initials: S
authors.lastname: Jamal
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D002675:Child, Preschool; D006801:Humans; D007890:Leiomyosarcoma / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome