Isolated tuberculosis of the ampulla of vater masquerading as periampullary carcinoma: a case report.
BACKGROUND
Isolated tuberculosis of the ampulla of Vater has not yet been reported. The clinical features of isolated periampullary tuberculosis are at times similar to those seen in patients with periampullary carcinoma. Diagnosis is difficult, and biopsy and culture of the suspected lesion are often negative for Mycobacterium tuberculosis.


METHODS
We herein describe one such case masquerading as periampullary carcinoma in a 70-year-old woman. Due to comorbid conditions only a local excision of the ampulla was carried out. Histopathology revealed giant cells in the absence of caseation necrosis and the presence of Mycobacterium tuberculosis was proven using the polymerase chain reaction.


CONCLUSIONS
Isolated tuberculosis of ampulla of Vater is extremely rare but must be kept in mind when making the differential diagnosis of isolated ampullary lesion.
Tewari
Mallika
M
Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India. mallika_vns@satyam.net.in
Mishra
Raghvendra Raman
RR
Kumar
Vinay
V
Kar
Amrita Ghosh
AG
Shukla
Hari S
HS
D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology*; D002761:Cholangitis / Q000175:diagnosis; D003138:Common Bile Duct Neoplasms / Q000175:diagnosis*; D004269:DNA, Bacterial / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics; D016133:Polymerase Chain Reaction; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology
D004269:DNA, Bacterial