title: Preformed silastic silos in the management of necrotizing enterocolitis.
abstract: Necrotizing enterocolitis (NEC) is sometimes complicated by abdominal compartment syndrome, a clinical syndrome characterized by multiple organ dysfunction that arises as a consequence of increased intra-abdominal pressure. The evolving clinical picture of NEC sometimes requires "second-look" operations done after initial abdominal exploration to more accurately gauge the optimal extent of surgery. Placing intestines in a preformed, spring-loaded, transparent Silastic silo, traditionally used in the staged treatment of gastroschisis, addresses both situations: decompression of the abdomen and allowing periodic inspection of the intestines. Standard silos were used in three infants with advanced (Bell Class 3) NEC without perforation before definitive surgery. Clinical indices and laboratory values were recorded during the patients' hospital courses. All three infants had extensive areas of intestinal ischemia and necrosis. FiO2, acidosis, and urinary output remained stable or improved in two patients. Silo placement corrected abdominal compartment syndrome in the third patient. Intestinal resection was required in all infants, each achieving surgical resolution of NEC. Two patients ultimately died from respiratory and neurologic complications. Application of a silo addresses abdominal compartment syndrome as a complication of NEC and allows continual inspection of the intestines. Physiological indices may improve the patient's overall clinical status.
authors.affiliation: Mercer University School of Medicine, Macon, Georgia, USA.
authors.forename: Amy B
authors.initials: AB
authors.lastname: Moore
authors.forename: Don K
authors.initials: DK
authors.lastname: Nakayama
mesh_terms: D004129:Dimethylpolysiloxanes; D020345:Enterocolitis, Necrotizing / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D014022:Tissue Survival; D014340:Trusses
chemical_list: D004129:Dimethylpolysiloxanes; C013830:baysilon