title: Short and long term failure of the modular oncology knee prosthesis.
abstract: This retrospective study investigated the modes of implant failure in 80 patients with modular oncology knee prostheses. Twenty patients (25%) required revision: 12 (60%) for stem loosening, 6 (30%) for bearing failure, and 2 (10%) for infection. Patients with bone sarcomas survived longer; however, long-term prosthetic survivorship was a problem. A higher failure rate was found in patients with tibial tumors and with adjuvant treatment of chemotherapy. This study demonstrates for improved long-term survivorship of modular oncology knee prostheses, there must be improvement in the methods of stem fixation, prosthetic materials, and bearing mechanics.
authors.affiliation: Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
authors.forename: Steven
authors.initials: S
authors.lastname: Gitelis
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Yergler
authors.forename: Neal
authors.initials: N
authors.lastname: Sawlani
authors.forename: Adam
authors.initials: A
authors.lastname: Schiff
authors.forename: Susan
authors.initials: S
authors.lastname: Shott
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation* / Q000401:mortality*; D001859:Bone Neoplasms / Q000401:mortality* / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D007087:Illinois / Q000453:epidemiology; D007593:Joint Instability / Q000401:mortality* / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery; D007720:Knee Prosthesis / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D012189:Retrospective Studies; D016019:Survival Analysis; D015996:Survival Rate; D055815:Young Adult