title: Proximal femoral endoprosthesis for the treatment of metastatic.
abstract: Traditional reconstructive options may not always be adequate to treat the extensive bone loss that can occur with metastatic disease of the proximal femur. Another method of treatment is resection of the proximal femur and reconstruction with an endoprosthesis. However, the more extensive surgery raises concern for a higher perioperative complication rate in this potentially medically unstable population. This study reviewed 57 patients with metastatic disease treated with 58 proximal femoral endoprostheses. The only perioperative complications were 2 symptomatic deep venous thromboses. Late complications included 3 dislocations, 2 deep venous thromboses, 1 pulmonary embolism, and 4 infections. Three deaths occurred during the perioperative period, all from underlying cancer. Proximal femoral endoprostheses offer a safe treatment option for patients with extensive metastatic disease.
authors.affiliation: Department of Orthopedic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77230-1402, USA.
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Cannon
authors.forename: Attiqa N
authors.initials: AN
authors.lastname: Mirza
authors.forename: Patrick P
authors.initials: PP
authors.lastname: Lin
authors.forename: Valerae O
authors.initials: VO
authors.lastname: Lewis
authors.forename: Alan W
authors.initials: AW
authors.lastname: Yasko
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D005266:Femoral Neoplasms / Q000556:secondary* / Q000601:surgery*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007593:Joint Instability / Q000209:etiology* / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000209:etiology*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology*