title: Benzaldehyde-functionalized polymer vesicles.
abstract: Polymer vesicles with diameters of ca. 100-600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO(45)-b-PVBA(26) in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.
authors.affiliation: Department of Chemistry, Washington University in Saint Louis, Saint Louis, Missouri 63130, USA.
authors.forename: Guorong
authors.initials: G
authors.lastname: Sun
authors.forename: Huafeng
authors.initials: H
authors.lastname: Fang
authors.forename: Chong
authors.initials: C
authors.lastname: Cheng
authors.forename: Peng
authors.initials: P
authors.lastname: Lu
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.forename: Amy V
authors.initials: AV
authors.lastname: Walker
authors.forename: John-Stephen A
authors.initials: JS
authors.lastname: Taylor
authors.forename: Karen L
authors.initials: KL
authors.lastname: Wooley
mesh_terms: D000818:Animals; D001547:Benzaldehydes / Q000737:chemistry*; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D003432:Cross-Linking Reagents / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D001547:Benzaldehydes; D003432:Cross-Linking Reagents; D011108:Polymers; D014867:Water; C032175:benzaldehyde