title: TFCat: the curated catalog of mouse and human transcription factors.
abstract: Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal (http://www.tfcat.ca).
authors.affiliation: Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada. debra@cmmt.ubc.ca
authors.forename: Debra L
authors.initials: DL
authors.lastname: Fulton
authors.forename: Saravanan
authors.initials: S
authors.lastname: Sundararajan
authors.forename: Gwenael
authors.initials: G
authors.lastname: Badis
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Hughes
authors.forename: Wyeth W
authors.initials: WW
authors.lastname: Wasserman
authors.forename: Jared C
authors.initials: JC
authors.lastname: Roach
authors.forename: Rob
authors.initials: R
authors.lastname: Sladek
mesh_terms: D000818:Animals; D004247:DNA / Q000378:metabolism; D030562:Databases, Protein; D006801:Humans; D051379:Mice; D011485:Protein Binding; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D014157:Transcription Factors; D004247:DNA