Two cases of hemichorea-hemiballism with nonketotic hyperglycemia: a new point of view.
Hemichorea-hemiballism (HCHB) is an usually continuous, nonpatterned, involuntary movement disorder caused by basal ganglia dysfunction, commonly due to a vascular lesion, described in nonketotic hyperglycemic patients. Particular computed tomography and magnetic resonance imaging findings have been described. The pathogenic mechanism of chorea arising during hyperglycemia and the nature of neuroimaging findings are unclear. In this paper we describe two elderly women with onset of HCHB during a hyperglycemic episode. The symptoms persisted in one of them after recovery of normal glycemia. The pathophysiological mechanism of the disease is discussed in the light of clinical and neuroradiological follow-up.
Battisti
Carla
C
Operative Unit of Neurology and Neurometabolic Diseases, Policlinico "Le Scotte", University of Siena, V.le Bracci, 2, 53100, Siena, Italy. Battisti@unisi.it
Forte
Francesca
F
Rubenni
Elisa
E
Dotti
Maria Teresa
MT
Bartali
Anna
A
Gennari
Paola
P
Federico
Antonio
A
Cerase
Alfonso
A
D000368:Aged; D000369:Aged, 80 and over; D001480:Basal Ganglia Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002819:Chorea / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D020820:Dyskinesias / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D020158:Hyperglycinemia, Nonketotic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed