title: An unusual cause of insomnia.
abstract: We report the case of a patient with tonsillar carcinoma, presenting with insomnia and symptoms of obstructive sleep apnoea/hypopnea syndrome (OSAHS), which were exacerbated following an increase in benzodiazepine dose. There is a growing body of evidence describing OSAHS in patients treated for head and neck cancer. However, to our knowledge, there are no reports relating to the population of patients with progressive disease, whose management is palliative. We would advise consideration be given to the possibility of OSAHS in a patient presenting with an oropharyngeal tumour and sleep disturbance and would also suggest caution in the prescription of benzodiazepines and other sedative medication to this group of patients.
authors.affiliation: St Barnabas House, Columbia Drive, Worthing, West Sussex, UK. ndando@doctors.org.uk
authors.forename: N
authors.initials: N
authors.lastname: Dando
authors.forename: S
authors.initials: S
authors.lastname: England
authors.forename: S
authors.initials: S
authors.lastname: Ford-Dunn
mesh_terms: D001569:Benzodiazepines / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010166:Palliative Care; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy / Q000209:etiology*; D014067:Tonsillar Neoplasms / Q000150:complications*
chemical_list: D001569:Benzodiazepines