Three new insecticidal sesquiterpene pyridine alkaloids from Celastrus angulatus.
Three new sesquiterpene pyridine alkaloids with a beta-dihydroagarofuran sesquiterpene skeleton, celangulatin G(1), H(2) and I(3), and one known alkaloid 4 were isolated from the middle-polar extracts of the root bark of Celastrus angulatus by bioassay-guided separation. Their chemical structures were elucidated mainly by the analyses of the MS and NMR spectral data. Celangulatin G(1), H(2), I(3) and 4 showed KD(50) against Mythimna separata were 849.61, 80.24, 96.29 and 50.98 microg g(-1), respectively.
Zhiqing
Ji
J
Department of Plant Protection, Northwestern Agricultural University, Yangling, Shaanxi, People's Republic of China.
Qidong
Zhang
Z
Baojun
Shi
S
Shaopeng
Wei
W
Mingan
Wang
W
Wenjun
Wu
W
D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D001681:Biological Assay; D031247:Celastrus / Q000737:chemistry*; D005247:Feeding Behavior / Q000187:drug effects; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D015394:Molecular Structure; D009036:Moths / Q000187:drug effects; D009539:Nicotinic Acids / Q000737:chemistry / Q000494:pharmacology*; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology*
D000470:Alkaloids; D007306:Insecticides; D009539:Nicotinic Acids; D011725:Pyridines; D012717:Sesquiterpenes; C540884:celangulatin G; C540885:celangulatin H; C540886:celangulatin I