title: Foot and mouth disease in the Lao People's Democratic Republic: II. Seroprevalence estimates, using structured surveillance and surveys of abattoirs.
abstract: An examination of the seroprevalence of foot and mouth disease (FMD) virus was conducted in the Lao People's Democratic Republic (Lao PDR) from 1996 to 2005, using structured surveillance and abattoir-based studies. Under structured surveillance, seropositivity ranged from 65.7% (Vientiane Capital, 1996) to 3% (Houaphan, 2005) for cattle and buffalo; and from 2.8% (Vientiane Capital, 1998) to 0% in separate studies of pigs. In each study, species composition was significantly associated with seroprevalence rates. For abattoir surveys, the majority of samples (60.5%) came from Vientiane Capital (33.0%), Savannakhet (14.0%) and Champasak (13.5%) provinces. The overall proportion of animals testing positive for the presence of antibodies against the FMD virus was 18.7% (ranging from 50.8% in Vientiane Province to 1% in Phongsali). Generally, antibodies against serotype O were the most prevalent. Cattle and buffalo that tested as seropositive were significantly older than the seronegative animals (p < 0.00005). The overall proportional seropositivity was significantly different for different species, as was the case with the antibodies against serotypes O, A and Asia 1. Some 22% of cattle, 55% of buffalo and 23% of pigs demonstrated seropositivity but this varied significantly between provinces.
authors.affiliation: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
authors.forename: S D
authors.initials: SD
authors.lastname: Blacksell
authors.forename: S
authors.initials: S
authors.lastname: Khounsy
authors.forename: J V
authors.initials: JV
authors.lastname: Conlan
authors.forename: L J
authors.initials: LJ
authors.lastname: Gleeson
authors.forename: A
authors.initials: A
authors.lastname: Colling
authors.forename: H A
authors.initials: HA
authors.lastname: Westbury
mesh_terms: D000003:Abattoirs / Q000706:statistics & numerical data*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002020:Buffaloes; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000517:prevention & control; D004196:Disease Outbreaks / Q000517:prevention & control / Q000706:statistics & numerical data / Q000662:veterinary; D005536:Foot-and-Mouth Disease / Q000453:epidemiology* / Q000517:prevention & control; D029544:Foot-and-Mouth Disease Virus / Q000276:immunology*; D007812:Laos / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D013045:Species Specificity; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000914:Antibodies, Viral