Selection of adequate optimization criteria in chromatographic separations.
Computer-assisted optimization of chromatographic separations is still a fruitful activity. In fact, advances in computerized data handling should make the application of systematic optimization strategies much easier. However, in most contemporary applications, the optimization criterion is not considered to be a key issue (Vanbel, J Pharm Biomed, 21:603-610, 1999). In this paper, an update of the importance of selecting adequate criteria in chromatographic separation is presented.
Vanbel
P F
PF
Polymer-Analysis Group, Van't Hoff Institute for Molecular Sciences (HIMS), Faculty of Science, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV Amsterdam, The Netherlands. pascale.vanbel@bluewin.ch
Schoenmakers
P J
PJ