title: Non-Doppler two dimensional strain imaging for evaluation of coronary artery disease.
abstract: Over the recent years, strain echocardiography has emerged as a quantitative technique for the evaluation of global and segmental cardiac function. Strain is a measure of deformation, expressed as a percent change in a segment's length compared to its predeformation length. Strain rate (SR) is the local rate of deformation or strain per unit time. Recently non-Doppler two dimensional strain imaging has been developed. This technique is based on tracking ultrasonic speckles from the two dimensional echocardiographic images. These speckles are followed over a number of successive frames, and myocardial velocity is calculated by measuring frame-to-frame changes. This technique is independent of the Doppler angle of incidence and allows measurement of several vectors of strain within myocardial tissue. Non-Doppler strain is a powerful tool, enabling detection of subtle abnormalities in myocardial function. Current evidence shows that non-Doppler strain imaging may allow identification of the early changes that occur with ischemic insult to the myocardium. It may also provide a tool for identification of scarred, non-viable myocardium, with similar accuracy to that of cardiac MRI. Non-Doppler strain imaging is likely to become a standard tool in the evaluation of patients with ischemic heart disease.
authors.affiliation: Noninvasive Cardiology, The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA. gila.perk@nyumc.org
authors.forename: Gila
authors.initials: G
authors.lastname: Perk
authors.forename: Itzhak
authors.initials: I
authors.lastname: Kronzon
mesh_terms: D003324:Coronary Artery Disease / Q000150:complications* / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004452:Echocardiography / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000209:etiology*