Antibacterial activity and bonding ability of an adhesive incorporating an antibacterial monomer DMAE-CB.
This study evaluated the antibacterial effect and microtensile bond strength of a resin-based adhesive containing an antibacterial monomer DMAE-CB (methacryloxylethyl cetyl dimethyl ammonium chloride). Cured specimens of 1, 2, and 3% DMAE-CB-containing Single Bond 2 (crosslinking monomer: Bis-GMA, dimethacrylates; functional monomer: HEMA) were prepared, and their antibacterial effects on Streptococcus mutans ATCC 25175 were investigated. Antibacterial property after 0, 30, 90, and 180 days of aging was also tested. Bonding ability of the experimental adhesive incorporating 3% DMAE-CB was evaluated by microtensile bond strength test. The cured experimental adhesive exhibited an inhibitory effect on S. mutans growth, and the adhesive containing 3% DMAE-CB showed higher antibacterial efficiency compared with those incorporating 1 or 2% anibacterial monomer. Antibacterial activities of the specimens lasted for at least 180 days. Microtensile bond strength test revealed that the bonding ability of the experimental adhesive was not significantly adversely affected by the incorporation of DMAE-CB. Therefore, dental adhesives with strong and long-lasting bacteriostatic property could be achieved by incorporating DMAE-CB without negatively influencing bonding ability.
Xiao
Yu-Hong
YH
Department of Stomatology, Kunming General Hospital of PLA, Kunming 650032, China.
Ma
Sai
S
Chen
Ji-Hua
JH
Chai
Zhi-Guo
ZG
Li
Fang
F
Wang
Ying-Jie
YJ
D000268:Adhesiveness; D000269:Adhesives / Q000737:chemistry; D000890:Anti-Infective Agents / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D001840:Dental Bonding; D017220:Dentin-Bonding Agents / Q000737:chemistry; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning / Q000379:methods; D008956:Models, Chemical; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013295:Streptococcus mutans / Q000378:metabolism*; D013718:Tensile Strength; D013997:Time Factors
D000269:Adhesives; D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D000644:Quaternary Ammonium Compounds; C540902:methacryloxylethyl cetyl dimethyl ammonium