[Myocardial infarction and pulmonary embolism in a 45 year-old woman with the prothrombin 20210A mutation--a case report].
We present a case of a 45-year-old-female who developed myocardial infarction and 6 weeks following first hospitalisation--pulmonary embolism. The disease was probably triggered by hormone replacement therapy. Coronary angioplasty and anticoagulant therapy with unfractioned heparin and acenokumarol were used with success. The woman and her 17-year-old daughter were shown to be heterozygous for prothrombin mutation G20210A. This case shows that trombophilia should be considered in young women with deep venous thrombosis, pulmonary embolism, venous thromboembolism or with myocardial infarction especially in women with high-risk factors.
Wozakowska-Kapłon
Beata
B
I Oddział Kardiologii, Swietokrzyskie Centrum Kardiologii, ul. Grunwaldzka 45, 25-736 Kielce. bw.kaplon@poczta.onet.pl
Szydziak-Zwierzyńska
Kinga
K
D000293:Adolescent; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000627:therapeutic use; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D009203:Myocardial Infarction / Q000139:chemically induced / Q000150:complications* / Q000175:diagnosis; D011516:Prothrombin / Q000235:genetics*; D011655:Pulmonary Embolism / Q000235:genetics* / Q000628:therapy
D000925:Anticoagulants; D011516:Prothrombin