title: Elaeagnoside, chymotrypsin inhibiting steroidal glucoside from Elaeagnus orientalis.
abstract: Elaeagnoside (1), a new steroidal glucoside, has been isolated from the chloroform fraction of Elaeagnus orientalis along with beta-sitosterol and 12-hydroxy-8,10-octadecadienoic acid. The structure of 1 has been elucidated with the help of chemical and spectral studies. It showed significant inhibitory activity against the enzyme chymotrypsin.
authors.affiliation: International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ayaz
authors.forename: Muhammad
authors.initials: M
authors.lastname: Riaz
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Ejaz
authors.initials: E
authors.lastname: Ahmad
authors.forename: Itrat
authors.initials: I
authors.lastname: Fatima
authors.forename: Muhammad
authors.initials: M
authors.lastname: Arif Lodhi
authors.forename: Muhammad Iqbal
authors.initials: MI
authors.lastname: Chaudhary
mesh_terms: D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D031263:Elaeagnaceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D012503:Saponins / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry*
chemical_list: D005960:Glucosides; D012503:Saponins; D013256:Steroids; C540881:elaeagnoside; D002918:Chymotrypsin