Unusual class 1 integron-associated gene cassette configuration found in IncA/C plasmids from Salmonella enterica.
IncA/C plasmids carrying an unusual cassette configuration in a class 1 integron and five further shared resistance genes, aacC4, aphA1, hph, sul2, and tetA(D) were found in Salmonella enterica serovars Senftenberg and Ohio. A deletion formed using a short region of homology in the 5' conserved segment and the orfF cassette created an array with only part of orfF followed by the aadA2 cassette. The IncA/C plasmids were not recoverable by conjugation, but additional conjugative resistance plasmids were present in some strains.
Evershed
Nick J
NJ
School of Molecular and Microbial Biosciences, The University of Sydney, NSW 2006, Australia.
Levings
Renee S
RS
Wilson
Neil L
NL
Djordjevic
Steven P
SP
Hall
Ruth M
RM
D000818:Animals; D001483:Base Sequence; D003227:Conjugation, Genetic; D006801:Humans; D032023:Integrons; D008969:Molecular Sequence Data; D010957:Plasmids; D019779:Salmonella enterica / Q000235:genetics*; D013552:Swine