title: The significance of Chlamydia trachomatis in urethritis and prostatitis - differences in therapeutic approach - Croatian experience.
abstract: We examined a total of 1014 patients over 18 years of age; 252 with urethritis and 762 with chronic prostatitis syndrome. the mean age of patients with urethritis was 32.7 and with prostatitis syndrome 37.6 years. Clinical symptoms of urethritis were present from a few days to several months. in patients with chronic prostatitis syndrome, symptoms were present for at least 3 months. Chlamydia trachomatis alone was confirmed in 26 (10%) and in combination with Ureaplasma urealyticum in 6 (2%) patients with urethritis. in 171 (68%) patients with urethritis neither C. trachomatis nor U. urealyticum or Mycoplasma hominis were found. C. trachomatis alone was confirmed in 70 (9%), and in combination with other microorganisms in 7 (1%) patients with chronic prostatitis syndrome. in Croatia, the frequency of chronic chlamydial prostatitis has not significantly changed in the last 10 years, while the frequency of infections among adolescents decreased. the recommended regimen for acute chlamydial urethritis in Croatia is azithromycin 1.0 g as a single dose, and a total dose of 4-4.5 g azithromycin for chronic chlamydial prostatitis.
authors.affiliation: University Hospital for Infectious Diseases, Zagreb, Croatia. vskerk@bfm.hr
authors.forename: Visnja
authors.initials: V
authors.lastname: Skerk
authors.forename: L
authors.initials: L
authors.lastname: Markovinovic
authors.forename: S
authors.initials: S
authors.lastname: Zekan
authors.forename: J
authors.initials: J
authors.lastname: Jaksic
authors.forename: S
authors.initials: S
authors.lastname: Zidovec Lepej
authors.forename: A
authors.initials: A
authors.lastname: Markotic
authors.forename: Vedrana
authors.initials: V
authors.lastname: Skerk
authors.forename: V
authors.initials: V
authors.lastname: Radosevic
authors.forename: L
authors.initials: L
authors.lastname: Cvitkovic
authors.forename: J
authors.initials: J
authors.lastname: Begovac
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000188:drug therapy / Q000453:epidemiology*; D002692:Chlamydia trachomatis; D002908:Chronic Disease; D017523:Croatia / Q000453:epidemiology; D006801:Humans; D008297:Male; D011472:Prostatitis / Q000188:drug therapy / Q000382:microbiology*; D014526:Urethritis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin