TFCat: the curated catalog of mouse and human transcription factors.
Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal (http://www.tfcat.ca).
Fulton
Debra L
DL
Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada. debra@cmmt.ubc.ca
Sundararajan
Saravanan
S
Badis
Gwenael
G
Hughes
Timothy R
TR
Wasserman
Wyeth W
WW
Roach
Jared C
JC
Sladek
Rob
R
D000818:Animals; D004247:DNA / Q000378:metabolism; D030562:Databases, Protein; D006801:Humans; D051379:Mice; D011485:Protein Binding; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D014157:Transcription Factors; D004247:DNA