title: A pediatric case study of treprostinil overdose.
abstract: This case study reports the effects of a treprostinil accidental overdose in a patient with pulmonary hypertension. Treprostinil is labeled for treatment of pulmonary hypertension with New York Heart Association (NYHA) Class II, III and IV symptoms. It is characterized as a long-acting prostacyclin analog that can be delivered by intravenous or subcutaneous continuous infusions. This pediatric case report describes a massive overdose without significant side effects, thus suggesting a beneficial therapeutic index in pediatric patients.
authors.affiliation: Philadelphia University, Pennsylvania, USA.
authors.forename: Melinda
authors.initials: M
authors.lastname: Walsh
authors.forename: Brian D
authors.initials: BD
authors.lastname: Hanna
mesh_terms: D000959:Antihypertensive Agents / Q000506:poisoning*; D002648:Child; D062787:Drug Overdose; D011464:Epoprostenol / Q000031:analogs & derivatives* / Q000506:poisoning; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*
chemical_list: D000959:Antihypertensive Agents; D011464:Epoprostenol; C427248:treprostinil