A pediatric case study of treprostinil overdose.
This case study reports the effects of a treprostinil accidental overdose in a patient with pulmonary hypertension. Treprostinil is labeled for treatment of pulmonary hypertension with New York Heart Association (NYHA) Class II, III and IV symptoms. It is characterized as a long-acting prostacyclin analog that can be delivered by intravenous or subcutaneous continuous infusions. This pediatric case report describes a massive overdose without significant side effects, thus suggesting a beneficial therapeutic index in pediatric patients.
Walsh
Melinda
M
Philadelphia University, Pennsylvania, USA.
Hanna
Brian D
BD
D000959:Antihypertensive Agents / Q000506:poisoning*; D002648:Child; D062787:Drug Overdose; D011464:Epoprostenol / Q000031:analogs & derivatives* / Q000506:poisoning; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*
D000959:Antihypertensive Agents; D011464:Epoprostenol; C427248:treprostinil