title: Pharmacological activity of compounds extracted from persimmon peel (Diospyros kaki THUNB.).
abstract: Persimmon peels (Diospyros kaki THUNB.) are discarded during the production of dried fruit. The 2-methoxy-4-vinylphenol (8) which is component of persimmon peel had high antioxidant activity on the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay and SOD (superoxide dismutase) assay. And (8) had higher tyrosinase inhibiting activity than that of arbutin using both L-tyrosine and L-DOPA as substrates. In addition, tyrosinase inhibiting activity of synthesized 2-methoxy-4-vinylphenol glycoside (8a) was studied. (8a) had tyrosinase inhibiting activity, suggesting that (8a) has possibilities for ingredient of cosmetics that are possessed of whitening effect.
authors.affiliation: Graduate School of System Engineering, Program in Systems Engineering, Kinki University, Hiroshima, Japan.
authors.forename: Satomi
authors.initials: S
authors.lastname: Fukai
authors.forename: Shinichi
authors.initials: S
authors.lastname: Tanimoto
authors.forename: Aki
authors.initials: A
authors.lastname: Maeda
authors.forename: Hitomi
authors.initials: H
authors.lastname: Fukuda
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Okada
authors.forename: Masato
authors.initials: M
authors.lastname: Nomura
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry; D002849:Chromatography, Gas; D029788:Diospyros / Q000033:anatomy & histology* / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D001713:Biphenyl Compounds; D005609:Free Radicals; D010455:Peptides; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl; D014442:Monophenol Monooxygenase