Chemoenzymatic syntheses of carbasugar analogues of nucleoside diphosphate sugars: UDP-carba-Gal, UDP-carba-GlcNAc, UDP-carba-Glc, and GDP-carba-Man.
Chemoenzymatic syntheses of several NDP-carba-sugars have been successfully carried out, and these essential cofactor analogues are expected to be selective inhibitors of glycosyltransferase enzymes.
Seo
Kyung-Chang
KC
Department of Chemistry, Pohang University of Sciecnce and Technology, Pohang, 790-784, Korea.
Kwon
Young-Geol
YG
Kim
Dae-Hee
DH
Jang
In-Sook
IS
Cho
Jin-Won
JW
Chung
Sung-Kee
SK
D004798:Enzymes / Q000737:chemistry*; D009702:Nucleoside Diphosphate Sugars / Q000138:chemical synthesis* / Q000737:chemistry
D004798:Enzymes; D009702:Nucleoside Diphosphate Sugars