15-Lipoxygenase inhibitory effects of prenylated flavonoids from Erythrina senegalensis.
One new pterocarpan (named erybraedin F) along with seven known prenylated flavonoids were isolated from the stem and root bark of the medicinal plant Erythrina senegalensis. The structures were elucidated by 1D and 2D NMR and MS. The pterocarpans were found to be strong inhibitors of 15-lipoxygenase.
Togola
Adiaratou
A
Section of Pharmacognosy, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, Oslo, Norway.
Hedding
Berte
B
Theis
Anette
A
Wangensteen
Helle
H
Rise
Frode
F
Smestad Paulsen
Berit
B
Diallo
Drissa
D
Egil Malterud
Karl
K
D004895:Erythrina / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy
D005419:Flavonoids; D016859:Lipoxygenase Inhibitors