title: The relationship between low bone mineral density and Parkinson's disease in a Korean population.
abstract: There have been few studies concerning osteoporosis in patients with Parkinson's disease (PD), even though patients with PD have a high incidence of falls. Using a Korean population, we investigated the association between bone mineral density (BMD) and PD. A total of 107 patients with PD were compared with age-matched and sex-matched normal controls. Using the Hoehn & Yahr staging system, we classified the patients with PD into three subgroups. Parts II and III of the Unified Parkinson's Disease Rating Scale were administered to evaluate the relationship between the severity of PD and BMD. In conclusion, in the PD population we found that decreased BMD was related to the severity of immobility of patients, and that BMD changes were greater at the femoral neck than the spine area. Therefore, we assert that clinicians should consider administering screening tests to elderly patients with PD and provide appropriate primary or secondary prophylactic treatment for osteoporosis.
authors.affiliation: Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: In-Uk
authors.initials: IU
authors.lastname: Song
authors.forename: Joong-Seok
authors.initials: JS
authors.lastname: Kim
authors.forename: Sang-Bong
authors.initials: SB
authors.lastname: Lee
authors.forename: Seon-Young
authors.initials: SY
authors.lastname: Ryu
authors.forename: Jae-Young
authors.initials: JY
authors.lastname: An
authors.forename: Du-shin
authors.initials: DS
authors.lastname: Jeong
authors.forename: Yeong-In
authors.initials: YI
authors.lastname: Kim
authors.forename: Kwang-Soo
authors.initials: KS
authors.lastname: Lee
mesh_terms: D015502:Absorptiometry, Photon; D000203:Activities of Daily Living; D000368:Aged; D015519:Bone Density / Q000502:physiology*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D015331:Cohort Studies; D015897:Comorbidity; D004185:Disability Evaluation; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology; D010300:Parkinson Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index