title: [Multidrug intoxication].
abstract: The authors report an suicide attempt by a 43 years old woman treated by Previscan, Effexor, Rivotril, and Stilnox for phlebitis anteriority and anxious-depressive disorders. On arrival to the emergency unit, the medical status and the patient history required a cardiovascular reanimation and gastric washing. The haemostasis analysis demonstrates an anticoagulant overdose and the prescription of vitamine K1 and PPSB was necessary. Later, the multidrug poisoning was demonstrated thanks to blood, urinary and gastric fluid high performance liquid chromatography toxicological analyses. This case report points out that biological and toxicological analyses are complementary. The first ones are useful to determine the emergency symptomatic cares, and to check the drugs' efficiency. The second ones, although longer, are necessary to identify with certainty incriminated drugs.
authors.affiliation: Laboratoire de biochimie, pharmacologie et toxicologie cliniques, Hôpital d'instruction des armées Percy, Clamart.
authors.forename: E
authors.initials: E
authors.lastname: Valero
authors.forename: A
authors.initials: A
authors.lastname: Bousquet
authors.forename: M
authors.initials: M
authors.lastname: Almon
authors.forename: P
authors.initials: P
authors.lastname: Vest
authors.forename: F
authors.initials: F
authors.lastname: Ceppa
authors.forename: C
authors.initials: C
authors.lastname: Pelletier
authors.forename: C
authors.initials: C
authors.lastname: Renard
mesh_terms: D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000925:Anticoagulants; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use; D003511:Cyclohexanols / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008875:Middle Aged; D010630:Phenindione / Q000031:analogs & derivatives / Q000627:therapeutic use; D010689:Phlebitis / Q000188:drug therapy*; D011725:Pyridines / Q000627:therapeutic use; D013406:Suicide, Attempted / Q000517:prevention & control*; D000069470:Venlafaxine Hydrochloride; D000077334:Zolpidem
chemical_list: D014151:Anti-Anxiety Agents; D000925:Anticoagulants; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D003511:Cyclohexanols; D006993:Hypnotics and Sedatives; D011725:Pyridines; D010630:Phenindione; D002998:Clonazepam; D000069470:Venlafaxine Hydrochloride; D000077334:Zolpidem; C017673:fluindione