title: One-year prospective intrapatient comparison of aspherical and spherical intraocular lenses in patients with bilateral cataract.
abstract: OBJECTIVE
  To conduct longitudinal, intrapatient comparisons of aspherical and spherical silicone intraocular lenses (IOL) of the same material and platform in patients undergoing bilateral cataract surgery.
  
  
  METHODS
  Prospective, randomized study.
  
  
  METHODS
  Sixty-two eyes of 31 patients were randomized to receive a silicone aspherical IOL (Tecnis Z9000; AMO Inc, Santa Ana, California, USA) in 1 eye and a silicone spherical IOL (CeeOn 911A; AMO Inc) in the other eye. Best spectacle-corrected visual acuity (BSCVA); corneal and ocular wavefront aberrations; contrast sensitivity under photopic (180 lux), intermediate (75 lux), and scotopic (15 lux) illumination; amount of IOL decentration and tilt; and degree of posterior capsular opacification were measured at 1, 3, 6, and 12 months after surgery. All-distance visual acuity (VA) was measured 3 months after surgery.
  
  
  RESULTS
  There were no significant differences between IOLs with regard to BSCVA, amount of IOL decentration and tilt, degree of posterior capsule opacification, and all-distance VA at any point after surgery. Regarding corneal wavefront aberrations, there was no difference in third- and fourth-order root mean square (RMS). In ocular wavefront aberrations, aspherical IOLs showed significantly lower fourth-order RMS (P < .001) than spherical IOLs throughout the study, but not in third-order RMS. Contrast sensitivity under photopic and mesopic conditions was not different between IOLs, but contrast sensitivity under scotopic conditions was significantly better with aspherical IOLs than with spherical IOLs (P < .01) at all measurement points.
  
  
  CONCLUSIONS
  The silicone aspherical IOL (Tecnis Z9000; AMO Inc) significantly reduced ocular spherical aberration and improved scotopic contrast sensitivity, and these results were consistent through the 1-year follow-up.
authors.affiliation: Meiwakai Medical Foundation, Miyata Eye Hospital, Miyazaki, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Ohtani
authors.forename: Susumu
authors.initials: S
authors.lastname: Gekka
authors.forename: Masato
authors.initials: M
authors.lastname: Honbou
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kataoka
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Minami
authors.forename: Kazunori
authors.initials: K
authors.lastname: Miyata
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Oshika
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications* / Q000628:therapy; D015350:Contrast Sensitivity / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D012826:Silicone Elastomers; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D012826:Silicone Elastomers