[Bowel preparation with sodium phosphate versus polyethylene glycol: a prospective, randomized, controlled clinical trial].
OBJECTIVE
To compare the efficacy, tolerance and safety between oral sodium phosphate(NaP) and polyethylene glycol(PEG) on bowel preparation.


METHODS
One hundred and fifteen inpatients were randomly divided into NaP group and PEG group. The questionnaire was designed for scoring by patients and doctors regarding to tolerance, taste, side effects and cleaning degree etc.


RESULTS
Compared with PEG group, NaP presented better tolerance, lower side effects and higher rate of adequate cleaning quality(P<0.05). NaP could cause electrolytic alterations, such as hyperphosphatemia, hypernatremia, hypocalcemia and hypopotassemia, but these changes were transient and without clinical significance.


CONCLUSIONS
Sodium phosphate is safe and effective for bowel preparation, and is better than polyethylene glycol in tolerance.
Yang
Guan-gen
GG
Department of Anorectum,Hangzhou Third Peopleos Hospital, Hangzhou 310009, China. yangguangen88@126.com
Wu
Xiao-chang
XC
Liao
Xiu-jun
XJ
Liu
Zhi-yong
ZY
Shen
Zhong
Z
Jin
Yong-jun
YJ
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000627:therapeutic use*; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011300:Preoperative Care / Q000379:methods*; D011446:Prospective Studies; D055815:Young Adult
D010710:Phosphates; D011092:Polyethylene Glycols; C018279:sodium phosphate