title: Cyproterone acetate- and ethinyloestradiol-containing oral contraceptive as a risk factor for upper extremity deep venous thrombosis-a case report.
abstract: Deep venous thrombosis of the upper extremity (UEDVT) is a rare variety of deep venous thrombosis. Compared to lower-extremity deep venous thrombosis, less is known about the risk factors for primary UEDVT. We report on a 27-year-old woman with UEDVT extending from the jugular and subclavian veins to the elbow. The thrombosis was possibly provoked by a shoulder trauma, in combination with heterozygosity for the prothrombin G20210A mutation and a protein S-deficiency, which may have been induced by the use of a cyproterone acetate- and ethinyloestradiol (CPA/EE)-containing oral contraceptive.
authors.affiliation: Selective Utrecht Medical Master (SUMMA), University Medical Center Utrecht, Utrecht, The Netherlands. Rickkapur@hotmail.com
authors.forename: Rick
authors.initials: R
authors.lastname: Kapur
authors.forename: Claire A I
authors.initials: CA
authors.lastname: Stramrood
authors.forename: Roger E G
authors.initials: RE
authors.lastname: Schutgens
authors.forename: B Sweder
authors.initials: BS
authors.lastname: van Asbeck