title: Prognostic clinical and radiological parameters for immediate facial nerve function following vestibular schwannoma surgery.
abstract: OBJECTIVE
  The paper aims to define the parameters available before surgery which could predict immediate facial nerve function after excision of a vestibular schwannoma (VS).
  
  
  METHODS
  Ninety-nine patients with VS operated consecutively by a single surgeon using an identical surgical technique have been evaluated retrospectively. Data were collected regarding patients' sex, age at onset of symptoms and at surgery, initial symptoms, neurological status at presentation, early post-operative neurological status and complications. The main radiological parameters included in the study were tumour extension pattern, diameters, shape, and volume, as well as extent of bony changes of the internal auditory canal.
  
  
  RESULTS
  As the tumour stage and volume increase, facial nerve function is worse after surgery (p < 0.001 and p < 0.05, respectively). Concomitantly, larger extra-meatal tumour diameters in three dimensions (sagittal, coronal and axial) led to worse function (p < 0.01). Anterior and/or caudal tumour extension (p = 0.001 and p = 0.004, respectively) had more significant correlation than posterior and/or cranial extension (p = 0.022 and p = 0.353, respectively). Polycyclic VS had the worst prognosis, followed by the tumours with oval shape. The extent of intra-meatal tumour growth does not correlate with immediate facial nerve outcome. The different angles, lengths and diameters of the internal auditory channel showed no significant correlation with facial nerve outcome. Patients with headache as an initial symptom and those with gait instability and/or pre-operative poor facial nerve function had significantly worse immediate facial nerve outcome.
  
  
  CONCLUSIONS
  Our data suggests that the analysis of the radiological and neurological patient data prior to surgery could give reliable clues regarding the immediate post-operative facial nerve function.
authors.affiliation: International Neuroscience Institute-Hannover, Rudolf Pichlmayr Str. 4, Hannover 30625, Germany. vgerganov@gmail.com
authors.forename: Venelin Miloslavov
authors.initials: VM
authors.lastname: Gerganov
authors.forename: Petra Margarete
authors.initials: PM
authors.lastname: Klinge
authors.forename: Mohsen
authors.initials: M
authors.lastname: Nouri
authors.forename: Lennart
authors.initials: L
authors.lastname: Stieglitz
authors.forename: Madjid
authors.initials: M
authors.lastname: Samii
authors.forename: Amir
authors.initials: A
authors.lastname: Samii