Polycyclic alkaloids via transannular Mannich reactions.
The tricyclic compound , representing the framework of the cylindricine and lepadiformine alkaloids, was prepared in a single operation via the first example of a transannular Mannich reaction involving a macrocyclic diketoamine .
Vital
Paulo
P
Department of Chemistry, Technical University of Denmark, 201 Kemitorvet, Lyngby, DK-2800 Kgs, Denmark.
Hosseini
Masood
M
Shanmugham
M Sundaram
MS
Gotfredsen
Charlotte H
CH
Harris
Pernille
P
Tanner
David
D