title: A randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of concurrent alcohol use disorder and pathological gambling.
abstract: The efficacy of naltrexone as a treatment for concurrent alcohol abuse or dependence and pathological gambling was evaluated in a randomized, double-blind, placebo-controlled trial. Fifty-two, mostly male, subjects were recruited from the community and received 11 weeks of medication during which cognitive-behavioral counseling was also provided. No significant group differences were found on any alcohol or gambling variable (ie, frequency, quantity, expenditures) at post-treatment or at the one year follow-up. However, a strong time effect was found suggesting that treatment, in general, was effective. The use of naltrexone to treat concurrent alcohol use and gambling problems was not supported.
authors.affiliation: Clinical Research Department, Center for Addiction and Mental Health, Toronto, Ontario, Canada. tony toneatto@camh.net
authors.forename: Tony
authors.initials: T
authors.lastname: Toneatto
authors.forename: Bruna
authors.initials: B
authors.lastname: Brands
authors.forename: Peter
authors.initials: P
authors.lastname: Selby