title: Impact of deoxynivalenol on the intestinal microflora of pigs.
abstract: Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities.
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.|French Institute of Agricultural Research (INRA) - UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 - France.
authors.forename: Yann J
authors.initials: YJ
authors.lastname: Waché
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Valat
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
authors.forename: Gilbert
authors.initials: G
authors.lastname: Postollec
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bougeard
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
authors.forename: Christine
authors.initials: C
authors.lastname: Burel
authors.affiliation: French Institute of Agricultural Research (INRA) - UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 - France.
authors.forename: Isabelle P
authors.initials: IP
authors.lastname: Oswald
authors.affiliation: French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Fravalo