title: A different approach to enantioselective organic synthesis: absolute asymmetric synthesis of organometallic reagents.
abstract: Voilà, optical activity: Both enantiomers of 1-chloroindene have been synthesized in high selectivity from solely achiral starting materials, and without using optically active catalysts (see scheme). These symmetry-breaking syntheses provide a proof-of-concept for a new approach to asymmetric synthesis. NCS=N-chlorosuccinimide.
authors.affiliation: Department of Chemistry, University of Gothenburg, 41296 Gothenburg, Sweden.
authors.forename: Anders
authors.initials: A
authors.lastname: Lennartson
authors.forename: Susanne
authors.initials: S
authors.lastname: Olsson
authors.forename: Jonas
authors.initials: J
authors.lastname: Sundberg
authors.forename: Mikael
authors.initials: M
authors.lastname: Håkansson