title: Effect of whole-body CT during trauma resuscitation on survival: a retrospective, multicentre study.
abstract: BACKGROUND
  The number of trauma centres using whole-body CT for early assessment of primary trauma is increasing. There is no evidence to suggest that use of whole-body CT has any effect on the outcome of patients with major trauma. We therefore compared the probability of survival in patients with blunt trauma who had whole-body CT during resuscitation with those who had not.
  
  
  METHODS
  In a retrospective, multicentre study, we used the data recorded in the trauma registry of the German Trauma Society to calculate the probability of survival according to the trauma and injury severity score (TRISS), revised injury severity classification (RISC) score, and standardised mortality ratio (SMR, ratio of recorded to expected mortality) for 4621 patients with blunt trauma given whole-body or non-whole-body CT.
  
  
  RESULTS
  1494 (32%) of 4621 patients were given whole-body CT. Mean age was 42.6 years (SD 20.7), 3364 (73%) were men, and mean injury-severity score was 29.7 (13.0). SMR based on TRISS was 0.745 (95% CI 0.633-0.859) for patients given whole-body CT versus 1.023 (0.909-1.137) for those given non-whole-body CT (p<0.001). SMR based on the RISC score was 0.865 (0.774-0.956) for patients given whole-body CT versus 1.034 (0.959-1.109) for those given non-whole-body CT (p=0.017). The relative reduction in mortality based on TRISS was 25% (14-37) versus 13% (4-23) based on RISC score. Multivariate adjustment for hospital level, year of trauma, and potential centre effects confirmed that whole-body CT is an independent predictor for survival (p </= 0.002). The number needed to scan was 17 based on TRISS and 32 based on RISC calculation.
  
  
  CONCLUSIONS
  Integration of whole-body CT into early trauma care significantly increased the probability of survival in patients with polytrauma. Whole-body CT is recommended as a standard diagnostic method during the early resuscitation phase for patients with polytrauma.
  
  
  BACKGROUND
  None.
authors.affiliation: Munich University Hospital, Department of Trauma Surgery-Campus Innenstadt, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Huber-Wagner
authors.forename: Rolf
authors.initials: R
authors.lastname: Lefering
authors.forename: Lars-Mikael
authors.initials: LM
authors.lastname: Qvick
authors.forename: Markus
authors.initials: M
authors.lastname: Körner
authors.forename: Michael V
authors.initials: MV
authors.lastname: Kay
authors.forename: Klaus-Jürgen
authors.initials: KJ
authors.lastname: Pfeifer
authors.forename: Maximilian
authors.initials: M
authors.lastname: Reiser
authors.forename: Wolf
authors.initials: W
authors.lastname: Mutschler
authors.forename: Karl-Georg
authors.initials: KG
authors.lastname: Kanz