title: Synthetic studies on daphnicyclidin A: enantiocontrolled construction of the BCD ring system.
abstract: An enantiocontrolled entry to the tricyclic core of daphnicyclidin A with five chiral centers including an all-carbon quaternary center is reported. The synthesis features a highly diastereoselective conjugate addition of nitromethane, an Ireland-Claisen rearrangement, and a tandem acyliminium/Mannich-type reaction.
authors.affiliation: Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai 980-8578, Japan.
authors.forename: Shuhei
authors.initials: S
authors.lastname: Ikeda
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Shibuya
authors.forename: Naoki
authors.initials: N
authors.lastname: Kanoh
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Iwabuchi