[Seizure activity in the EEG of rats sensitive and resistant to pentylenetetrazol kindling].
Rats were subjected to pentylenetetrazol kindling and divided into 2 groups according to their ability to demonstrate convulsions: the "sensitive" and "tresistant" rats groups. Both groups demonstrated EEG afterdischarges; however, the number of the EEG seizures in "sensitive" rats was 60% higher, the latency by 45 sec longer, and the total duration during the first 45 min after injection 70% longer as compared to the "resistant" rats. The average duration of a single EEG seizure did not differ in these groups. The average EEG frequency power peak at 7.2 Hz was more pronounced in the "resistant" group. Thus, pentylenetetrazol kindling induces epileptiform activity in the rat EEG irrespective of the appearance of behavioral seizures; however, characteristics of this activity differ significantly between the "sensitive" and "resistant" rats.
Pavlova
T V
TV
Fesenko
G N
GN
Gekht
A B
AB
Gulieva
N V
NV
Koval'zon
V M
VM