title: Patients and the public deserve big changes in evaluation of drugs.
authors.affiliation: Mario Negri Institute for Pharmacological Research, Via Giuseppe La Masa 19, 20156 Milan, Italy. garattini@marionegri.it
authors.forename: Silvio
authors.initials: S
authors.lastname: Garattini
authors.forename: Iain
authors.initials: I
authors.lastname: Chalmers