title: Biomechanical evaluation of plate osteosynthesis of distal fibula fractures with biodegradable devices.
abstract: BACKGROUND
  This study compared fixation with a titanium one-third tubular plate and one lag-screw vs. fixation with biodegradable plates with one lag-screw applied with two different plate-screw patterns.
  
  
  METHODS
  Ten pairs of fibulas were osteotomied, plated (titanium plate with one lag screw vs. absorbable 2/8 plate-screws crossing vs. 0/8 plate-screws crossing the osteotomy gap). and tested in torsion and bending to obtain stiffness and neutral-zone (NZ) data. Tests were performed using 5 load cycles. No load to failure was performed. Biodegradation was simulated by 6 week immersion in phosphate-buffered saline after which the testing protocol was repeated. The specimens were then loaded with 100 N in bending.
  
  
  RESULTS
  Post-implantation, there were no significant differences, in torsion and bending, regarding the NZ or the stiffness, between the 2/8 biodegradable plate and the titanium plate. The 0/8 pattern performed significantly less well in terms of stiffness and NZ in the initial torsion test, and significantly less well in terms of stiffness in the initial bending test. After 6 weeks' immersion, all biodegradable constructs showed a significantly larger NZ and significantly reduced bending and torsional stiffness. When loaded with 100 N, four of the six 0/8 osteosyntheses failed. There were no significant differences between the 2/8 pattern and the titanium plates.
  
  
  CONCLUSIONS
  In a model of a Weber-B fracture, the use of a 2/8 biodegradable plate construct initially did not differ statistically to that obtained with a one-third tubular titanium plate. After immersion the 2/8 construct withstood some physiological load.
  
  
  CONCLUSIONS
  For the fixation of ankle fractures with a biodegradable plate of the type employed in this study, the use of fracture-gap-crossing screws is recommended.
authors.affiliation: Kajetan.Klos@med.uni-jena.de
authors.forename: Kajetan
authors.initials: K
authors.lastname: Klos
authors.forename: Stefanie
authors.initials: S
authors.lastname: Sauer
authors.forename: Konrad
authors.initials: K
authors.lastname: Hoffmeier
authors.forename: Florian
authors.initials: F
authors.lastname: Gras
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Fröber
authors.forename: Gunther O
authors.initials: GO
authors.lastname: Hofmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Mückley