title: Synthesis of (E)-3-(isobenzofuran-3(1H)-ylidene)indolin-2-ones by the palladium-catalyzed intramolecular C-H functionalization process.
abstract: A novel and selective protocol has been developed for the synthesis of (E)-3-(isobenzofuran-3(1H)-ylidene)indolin-2-ones by Pd-catalyzed oxidative intramolecular C-H functionalization reactions of various 3-(2-(hydroxymethyl)aryl)-N-methyl-N-arylpropiolamides in moderate yields. Mechanisms involving a C-H activation process were proposed for this transformation on the basis of the observed values of kinetic isotope effects.
authors.affiliation: Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha 410081, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Peng
authors.forename: Bo-Xiao
authors.initials: BX
authors.lastname: Tang
authors.forename: Shao-Feng
authors.initials: SF
authors.lastname: Pi
authors.forename: Yun
authors.initials: Y
authors.lastname: Liang
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li