title: Radical hysterectomy for invasive cervical cancer during pregnancy: a retrospective analysis of a single institution experience.
abstract: OBJECTIVE
  To evaluate long-term prognosis and patient safety for a radical hysterectomy in pregnant women with invasive cervical cancer.
  
  
  METHODS
  We retrospectively analyzed 12 cases of radical hysterectomy (RH) performed for invasive cervical cancer during pregnancy. Four patients underwent RH with the fetus in situ and another eight patients underwent RH followed by cesarean section.
  
  
  RESULTS
  The median treatment period was 17 weeks of gestation (range: 9 to 39), the mean blood loss was 550.1 +/- 162.5 g (range: 275 to 850). Pelvic lymph node metastases were observed in three patients and parametrial invasion was observed in one patient. Although one patient experienced a recurrence at the vaginal stump, all patients were alive at a median follow-up interval of 105 months (range: 61 to 234).
  
  
  CONCLUSIONS
  RH during pregnancy can be safely performed even with the fetus in situ and a subsequent cesarean section.
authors.affiliation: Department of Obstetrics and Gynecology, Kinki University School of Medicine, Osaka, Japan. watanabe@med.kindai.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Tsuritani
authors.forename: T
authors.initials: T
authors.lastname: Kataoka
authors.forename: K
authors.initials: K
authors.lastname: Kanemura
authors.forename: M
authors.initials: M
authors.lastname: Shiina
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: H
authors.initials: H
authors.lastname: Hoshiai