title: New oral anticoagulants: not quite there yet.
abstract: The results of 3 large randomized trials of activated factor X inhibitors, for the prevention of venous thromboembolism, recently became available. Similar data for orally active thrombin inhibitors is also available from recent trials. In this review, we attempt to provide a balanced perspective on the relative merits and demerits of the new, orally active anticoagulants, and speculate on the future of these agents in clinical practice.
authors.affiliation: Department of Medicine, McMaster University, Hamilton, ON, Canada. karthik2010@gmail.com
authors.forename: Ganesan
authors.initials: G
authors.lastname: Karthikeyan
authors.forename: John W
authors.initials: JW
authors.lastname: Eikelboom
authors.forename: Jack
authors.initials: J
authors.lastname: Hirsh