Treatment of massive pancreaticojejunal anastomotic hemorrhage after pancreatoduodenectomy.
OBJECTIVE
To compare the treatment modalities for patients with massive pancreaticojejunal anastomotic hemorrhage after pancreatoduodenectomy (PDT).


METHODS
A retrospective study was undertaken to compare the outcomes of two major treatment modalities: transcatheter arterial embolization (TAE) and open surgical hemostasis. Seventeen patients with acute massive hemorrhage after PDT were recruited in this study. A comparison of two treatment modalities was based upon the clinicopathological characteristics and hospitalization stay, complications, and patient prognosis of the patients after surgery.


RESULTS
Of the 11 patients with massive hemorrhage after PDT treated with TAE, 1 died after discontinuing treatment, the other 10 stopped bleeding completely without recurrence of hemorrhage. All the 10 patients recovered well and were discharged, with a mean hospital stay of 10.45 d after hemostasis. The patients who underwent TAE twice had a re-operation rate of 18.2% and a mortality rate of 0.9%. Among the six patients who received open surgical hemostasis, two underwent another round of open surgical hemostasis. The mortality was 50%, and the recurrence of hemorrhage was 16.67%, with a mean hospital stay of 39.5 d.


CONCLUSIONS
TAE is a safe and effective treatment modality for patients with acute hemorrhage after PDT. Vasography should be performed to locate the bleeding site.
Liu
Chen
C
Billiary I Unit of Eastern Hepatobilliary Surgery Hospital, Shanghai, China.
Qiu
Ying-He
YH
Luo
Xiang-Ji
XJ
Yi
Bin
B
Jiang
Xiao-Qing
XQ
Tan
Wei-Feng
WF
Yu
Yong
Y
Wu
Meng-Chao
MC