title: Focal segmental glomerulosclerosis as a complication of graft-versus-host disease.
abstract: BACKGROUND
  A 54-year-old man with multiple myeloma underwent peripheral blood stem cell transplantation (PBSCT) with cells donated by his human leukocyte antigen (HLA)-identical sister. Eight months after PBSCT, the patient experienced chronic graft-versus-host disease with skin involvement (generalized erythema), mucosal ulceration, sicca syndrome, and elevated liver enzymes. Two years after PBSCT, the patient developed nephrotic syndrome with massive proteinuria, which required hospitalization.
  
  
  METHODS
  Physical examination, blood and urine analyses, liver function tests, 24 h urinary albumin excretion and renal biopsy.
  
  
  METHODS
  Focal segmental glomerulosclerosis as a complication of graft-versus-host disease.
  
  
  RESULTS
  Prednisone, ciclosporin and an angiotensin-converting-enzyme inhibitor.
authors.affiliation: Renal Unit, Sant'Andrea University Hospital, University of Rome La Sapienza, Rome, Italy. clafofi@tiscali.it
authors.forename: Claudia
authors.initials: C
authors.lastname: Fofi
authors.forename: Simona
authors.initials: S
authors.lastname: Barberi
authors.forename: Antonella
authors.initials: A
authors.lastname: Stoppacciaro
authors.forename: Giorgio
authors.initials: G
authors.lastname: Punzo
authors.forename: Paolo
authors.initials: P
authors.lastname: Menè