title: Stereoselective synthesis of amphidinolide T1.
abstract: A highly stereoselective total synthesis of amphidinolide T1 is achieved using Sharpless asymmetric epoxidation, base-induced epoxide opening, radical cyclization, diastereoselective reduction followed by allylation, Evans methylation, base-induced reductive elimination, umpolung reaction, chemoselective oxidation, and regioselective macrolactonization.
authors.affiliation: Organic Chemistry Division I, Indian Institute of Chemical Technology, Hyderabad 500607, India.
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav
authors.forename: Ch Suresh
authors.initials: ChS
authors.lastname: Reddy