Pi-activated alcohols: an emerging class of alkylating agents for catalytic Friedel-Crafts reactions.
The direct functionalization of aromatic compounds, via Friedel-Crafts alkylation reactions with alcohols, is one of the cornerstones in organic chemistry. The present emerging area deals with the recent advances in the use of pi-activated alcohols in the catalytic and stereoselective construction of benzylic stereocenters.
Bandini
Marco
M
Dipartimento di Chimica G. Ciamician, Alma Mater Studiorum, Università di Bologna, via Selmi 2, 40126, Bologna, Italy. marco.bandini@unibo.it
Tragni
Michele
M