Characterization of pu-erh tea using chemical and metabolic profiling approaches.
In this study, the chemical constituents of pu-erh tea, black tea, and green tea, as well as those of pu-erh tea products of different ages, were analyzed and compared using a chemical profiling approach. Differences in tea processing resulted in differences in the chemical constituents and the color of tea infusions. Human biological responses to pu-erh tea ingestion were also studied by using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOFMS) in conjunction with multivariate statistical techniques. Metabolic alterations during and after pu-erh tea ingestion were characterized by increased urinary excretion of 5-hydroxytryptophan, inositol, and 4-methoxyphenylacetic acid, along with reduced excretion of 3-chlorotyrosine and creatinine. This study highlights the potential for metabonomic technology to assess nutritional interventions and is an important step toward a full understanding of pu-erh tea and its influence on human metabolism.
Xie
Guoxiang
G
Shanghai Center for Systems Biomedicine, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
Ye
Mao
M
Wang
Yungang
Y
Ni
Yan
Y
Su
Mingming
M
Huang
Hua
H
Qiu
Mingfeng
M
Zhao
Aihua
A
Zheng
Xiaojiao
X
Chen
Tianlu
T
Jia
Wei
W