title: Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma.
abstract: Although germ cell tumors are the most common malignancy in young men, extragonadal germ cell tumors are rare. Gastric metastasis presenting initially as upper gastrointestinal hemorrhage is also exceedingly rare. A 27-year-old man presented at our hospital with tarry stool. Gastric fiberscopy images revealed a bleeding gastric polypoid lesion in the anterior wall of the gastric body, from which a biopsy specimen was obtained. Histopathological analysis of the biopsy showed syncytiotrophoblast-like cells with multiple, large nuclei, consistent with choriocarcinoma. Based on these results, our diagnosis was extragonadal retroperitoneal germ cell tumor with gastric metastasis.
authors.affiliation: Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan. tomoyosi@juntendo.ac.jp
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Shibuya
authors.forename: Taro
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authors.lastname: Osada
authors.forename: Tomohiro
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authors.lastname: Kodani
authors.forename: Mariko
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authors.lastname: Hojo
authors.forename: Hiroaki
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authors.lastname: Saito
authors.forename: Hiroya
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authors.lastname: Ueyama
authors.forename: Junko
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authors.lastname: Kato
authors.forename: Akihito
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authors.lastname: Nagahara
authors.forename: Michiro
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authors.lastname: Otaka
authors.forename: Tatsuo
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authors.lastname: Ogihara
authors.forename: Keiji
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authors.lastname: Nagao
authors.forename: Makoto
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authors.lastname: Fujime
authors.forename: Sumio
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authors.lastname: Watanabe