Cervical signet-ring cell carcinoma presenting as a synchronous primary carcinoma with uterine adenocarcinoma.
BACKGROUND
Synchronous primary gynecologic tumors are relatively uncommon with the diagnosis often made following initial surgery.


METHODS
A multiparous female in her 50s with postmenopausal bleeding was referred to our institution with a biopsy-proven diagnosis of endometrial cancer. Preoperative physical exam revealed a suspicious cervical lesion and upon biopsy she was found to have a signet-ring cell carcinoma of the cervix. Secondary to morbid obesity, the patient was not a candidate for a radical hysterectomy and was treated with curative radiation for stage IB 1 cervical carcinoma and clinical stage I endometrial carcinoma.


CONCLUSIONS
Cervical signet-ring cell carcinoma is an extremely rare pathologic diagnosis. The preoperative discovery of synchronous primary gynecological tumors necessitates individualized planning and treatment.
Lowery
William J
WJ
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Fort Sam Houston, TX 78234, USA.
Difurio
Megan J
MJ
Sundborg
Michael J
MJ
Leath
Charles A
CA