Intra-oral schwannoma: case report and literature review.
Schwannoma is a relatively uncommon, slow-growing benign tumor that is derived apparently from the Schwann cells. The tongue is the most common site, followed by the palate, floor of mouth, buccal mucosa, lips, and jaws. It can present itself at any age. Usually, this lesion is not taken into account during clinical practice and the differential diagnosis includes numerous benign neoformations based on epithelial and connective tissues. Immunohistochemical features can be useful in determining the neural differentiation. Anti-S100 protein is probably the most used antibody to identify this lesion. The schwannoma is usually a solitary lesion, and can be multiple when associated with neurofibromatosis. In the current study, authors report a case of an intraoral schwannoma situated at the vestibule with 20 years of evolution treated by complete surgical excision. The diagnosis was established based on clinical, histopathological, and immunohistochemical aspects. The patient is under clinical control, with no signs of recurrence even after four years.
Martins
Manoela Domingues
MD
Department of Rehabilitation Science, Post-Graduation Program, Nove de Julho University, São Paulo-SP, Brazil. manomartins@gmail.com
Anunciato de Jesus
Luciane
L
Fernandes
Kristianne Porta Santos
KP
Bussadori
Sandra Kalil
SK
Taghloubi
Saad Ahmad
SA
Martins
Marco Antonio Trevizani
MA