title: Synthesis of aromatic esters via Pd-catalyzed decarboxylative coupling of potassium oxalate monoesters with aryl bromides and chlorides.
abstract: Pd-catalyzed decarboxylative cross-coupling of aryl iodides, bromides, and chlorides with potassium oxalate monoesters has been discovered. This reaction is potentially useful for laboratory-scale synthesis of aryl and alkenyl esters. Bulky, electron-rich bidentate phosphine ligands are preferred in the reaction, whereas Cu is not needed for decarboxylation. Theoretical calculations suggest a five-coordinate Pd(II) transition state for decarboxylation with an energy barrier of approximately 30 kcal/mol.
authors.affiliation: Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Shang
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu
authors.forename: Jia-Bin
authors.initials: JB
authors.lastname: Li
authors.forename: Song-Lin
authors.initials: SL
authors.lastname: Zhang
authors.forename: Qing-Xiang
authors.initials: QX
authors.lastname: Guo
authors.forename: Lei
authors.initials: L
authors.lastname: Liu