Factors affecting postoperative cerebrospinal fluid leaks after retrosigmoidal craniotomy for vestibular schwannomas.
OBJECTIVE
The aim of this study was to identify patients likely to develop CSF leaks after vestibular schwannoma surgery using a retrospective analysis for the identification of risk factors.


METHODS
Between January 2001 and December 2006, 420 patients underwent retrosigmoidal microsurgical tumor removal in a standardized procedure. Of these 420 patients, 363 underwent treatment for the first time, and 27 suffered from recurrent tumors. Twenty-six patients had bilateral tumors due to neurofibromatosis Type 2, and 4 patients had previously undergone radiosurgical treatment. An analysis was performed to examine the incidence of postoperative CSF fistulas in all 4 groups.


RESULTS
The incidence of CSF leakage was higher in the tumor recurrence group (11.1%) than in patients undergoing surgery for the first time (4.4%). There were no CSF fistulas in the neurofibromatosis Type 2 group or in patients with preoperative radiosurgical treatment. Tumor size was identified as a possible risk factor in a previous study.


CONCLUSIONS
Surgery for recurrent tumors is a significant risk factor for the development of CSF leaks.
Stieglitz
Lennart H
LH
Department of Neurosurgery, International Neuroscience Institute, Hannover, Germany. lennart@stieglitze.de
Wrede
Karsten H
KH
Gharabaghi
Alireza
A
Gerganov
Venelin M
VM
Samii
Amir
A
Samii
Madjid
M
Luedemann
Wolf O
WO