An improved procedure for nucleoside synthesis using glycosyl trifluoroacetimidates as donors.
Using glycosyl trifluoroacetimidates as donors and nitromethane (or acetonitrile) as solvent, silylation and subsequent glycosylation were realized in a 'one-pot' procedure to provide the corresponding nucleosides derivatives in high yields. [structure: see text].
Liao
Jinxi
J
Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
Sun
Jiansong
J
Yu
Biao
B