Characteristics of the antibodies of two patients who developed daytime hyperglycemia and morning hypoglycemia because of insulin antibodies.
We encountered two patients who developed daytime hyperglycemia and early morning hypoglycemia because of insulin antibody (IA) that the affinity was extremely lower and the capacity extremely higher than those of IA in the insulin autoimmune syndrome, after their insulin treatment were changed from human insulin to analog insulin.
Ishizuka
Tsuneo
T
Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8574, Japan.
Ogawa
Susumu
S
Mori
Takefumi
T
Nako
Kazuhiro
K
Nakamichi
Takashi
T
Oka
Yoshitomo
Y
Ito
Sadayoshi
S