title: Cervical signet-ring cell carcinoma presenting as a synchronous primary carcinoma with uterine adenocarcinoma.
abstract: BACKGROUND
  Synchronous primary gynecologic tumors are relatively uncommon with the diagnosis often made following initial surgery.
  
  
  METHODS
  A multiparous female in her 50s with postmenopausal bleeding was referred to our institution with a biopsy-proven diagnosis of endometrial cancer. Preoperative physical exam revealed a suspicious cervical lesion and upon biopsy she was found to have a signet-ring cell carcinoma of the cervix. Secondary to morbid obesity, the patient was not a candidate for a radical hysterectomy and was treated with curative radiation for stage IB 1 cervical carcinoma and clinical stage I endometrial carcinoma.
  
  
  CONCLUSIONS
  Cervical signet-ring cell carcinoma is an extremely rare pathologic diagnosis. The preoperative discovery of synchronous primary gynecological tumors necessitates individualized planning and treatment.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Fort Sam Houston, TX 78234, USA.
authors.forename: William J
authors.initials: WJ
authors.lastname: Lowery
authors.forename: Megan J
authors.initials: MJ
authors.lastname: Difurio
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Sundborg
authors.forename: Charles A
authors.initials: CA
authors.lastname: Leath