title: Stepwise surface encoding for high-throughput assembly of nanoclusters.
abstract: Self-assembly offers a promising method to organize functional nanoscale objects into two-dimensional (2D) and 3D superstructures for exploiting their collective effects. On the other hand, many unique phenomena emerge after arranging a few nanoscale objects into clusters, the so-called artificial molecules. The strategy of using biomolecular linkers between nanoparticles has proven especially useful for construction of such nanoclusters. However, conventional solution-based reactions typically yield a broad population of multimers or isomers of clusters; furthermore, the efficiency of fabrication is often limited. Here, we describe a novel high-throughput method for designing and fabricating clusters using DNA-encoded nanoparticles assembled on a solid support in a stepwise manner. This method efficiently imparts particles with anisotropy during their assembly and disassembly at a surface, generating remarkably high yields of well-defined dimer clusters and Janus (two-faced) nanoparticles. The method is scalable and modular, assuring large quantities of clusters of designated sizes and compositions.
authors.affiliation: Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Mathew M
authors.initials: MM
authors.lastname: Maye
authors.forename: Dmytro
authors.initials: D
authors.lastname: Nykypanchuk
authors.forename: Marine
authors.initials: M
authors.lastname: Cuisinier
authors.forename: Daniel
authors.initials: D
authors.lastname: van der Lelie
authors.forename: Oleg
authors.initials: O
authors.lastname: Gang