title: Fluid replacement following dehydration reduces oxidative stress during recovery.
abstract: To investigate the effects of hydration status on oxidative DNA damage and exercise performance, 10 subjects ran on a treadmill until exhaustion at 80% VO(2max) during four different trials [control (C), 3% dehydration (D), 3% dehydration+water (W) or 3% dehydration+sports drink (S)]. Dehydration significantly decreased exercise time to exhaustion (D<C and S). Plasma MDA levels were significantly higher at pre-exercise in D than C. Plasma TAS was significantly lower at pre-exercise in C and S than in D, and was significantly lower in S than D at 60min of recovery. Dehydration significantly increased oxidative DNA damage during exercise, but fluid replacement with water or sports drink alleviated it equally. These results suggest that (1) dehydration impairs exercise performance and increases DNA damage during exercise to exhaustion; and (2) fluid replacement prolongs exercise endurance and attenuates DNA damage.
authors.affiliation: Department of Physical Education, Yonsei University, Shinchon-Dong, Seodaemun-Gu, Seoul, South Korea.
authors.forename: Il-Young
authors.initials: IY
authors.lastname: Paik
authors.forename: Myung-Hyun
authors.initials: MH
authors.lastname: Jeong
authors.forename: Hwa-Eun
authors.initials: HE
authors.lastname: Jin
authors.forename: Young-Il
authors.initials: YI
authors.lastname: Kim
authors.forename: Ah-Ram
authors.initials: AR
authors.lastname: Suh
authors.forename: Su-Youn
authors.initials: SY
authors.lastname: Cho
authors.forename: Hee-Tae
authors.initials: HT
authors.lastname: Roh
authors.forename: Chan-Ho
authors.initials: CH
authors.lastname: Jin
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Suh