title: [Neural crest disorders and Hirschsprung's disease].
abstract: The term Neurocristopathy describes a group of conditions caused by aberrations in growth, migration and differentiation of neural crest cells. In this sense, Hirschsprung's disease is a consequence of a failure in neural crest cells migration to distal intestine and in consequence it is considered to be part of neurocristopathy concept. This concept includes several diseases that can present either alone or in combination as a syndrome. We present 4 patients suffering Hirschsprung's disease associated with others neurocristopathies: 1 Waardenburg's syndrome, 1 congenital central hypoventilation syndrome or Ondine's curse, 1 ganglioneuroblastoma and 1 patient with bilateral sensory deafness.
authors.affiliation: Servicio de Cirugía Pediátrica, Hospital Infantil Universitario Niño Jesús, Madrid. rocioespinosagongora@hotmail.com
authors.forename: R
authors.initials: R
authors.lastname: Espinosa
authors.forename: J L
authors.initials: JL
authors.lastname: Alonso Calderón