title: Wound dehiscence: is still a problem in the 21th century: a retrospective study.
abstract: BACKGROUND
  The aim of this study was to evaluate the risk factors of wound dehiscence and determine which of them can be reverted.
  
  
  METHODS
  We retrospectively analyzed 3500 laparotomies. Age over 75 years, diagnosis of cancer, chronic obstructive pulmonary disease, malnutrition, sepsis, obesity, anemia, diabetes, use of steroids, tobacco use and previous administration of chemotherapy or radiotherapy were identified as risk factors
  
  
  RESULTS
  Fifteen of these patients developed wound dehiscence. Emergency laparotomy was performed in 9 of these patients. Patients who had more than 7 risk factors died.
  
  
  CONCLUSIONS
  It is important for the surgeon to know that wound healing demands oxygen consumption, normoglycemia and absence of toxic or septic factors, which reduces collagen synthesis and oxidative killing mechanisms of neutrophils. Also the type of abdominal closure may plays an important role. The tension free closure is recommended and a continuous closure is preferable. Preoperative assessment so as to identify and remove, if possible, these risk factors is essential, in order to minimize the incidence of wound dehiscence, which has a high death rate.
authors.affiliation: Department of Surgrery, Messologi General Hospital, Messologi, Greece. jspil@in.gr.
authors.forename: John
authors.initials: J
authors.lastname: Spiliotis
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Tsiveriotis
authors.forename: Anastasios D
authors.initials: AD
authors.lastname: Datsis
authors.forename: Archodoula
authors.initials: A
authors.lastname: Vaxevanidou
authors.forename: Georgios
authors.initials: G
authors.lastname: Zacharis
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Giafis
authors.forename: Spyros
authors.initials: S
authors.lastname: Kekelos
authors.forename: Athanasios
authors.initials: A
authors.lastname: Rogdakis