title: [Whole-body cryotherapy in patients with inflammatory rheumatic disease. A prospective study].
abstract: BACKGROUND
  As yet, whole-body cryotherapy is especially used for the therapy of chronic inflammatory arthritis. An analgetic effect has been described in several studies. However, only few data exist concerning the long-term effects of this therapy.
  
  
  METHODS
  A total of 60 patients with rheumatoid arthritis (n = 48), and ankylosing spondylitis (n = 12) was analyzed. Patients underwent treatment with whole-body cryotherapy twice a day. The average age was 55.7 +/- 10.33. The study group consisted of 48 female and twelve male patients. The average number of therapeutic treatments with cryotherapy was 15.8 +/- 8.37, the average follow-up 63.4 +/- 63.48 days.
  
  
  RESULTS
  13 patients (21.7%) discontinued treatment because of adverse effects. For patients with rheumatoid arthritis, DAS28 (Disease Activity Score) and VAS (visual analog scale) were determined. A significant reduction of both parameters was found (DAS 3.9 +/- 1.22 vs. 3.4 +/- 1.08; p < 0.01; VAS 51.4 +/- 16.62 vs. 37.9 +/- 19.13; p < 0.01). BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) was analyzed for patients with ankylosing spondylitis, and also showed a significant reduction (4.4 +/- 1.91 vs. 3.1 +/- 1.34; p = 0.01).
  
  
  CONCLUSIONS
  Thus, whole-body cryotherapy is an effective option in the concept of treatment of inflammatory rheumatic diseases. The relief of pain allows an intensification of physiotherapy. A significant reduction of pain over a period of 2 months could be shown.
authors.affiliation: Praxis für Allgemeinmedizin (Inhaber: MR Dr. H.-P. Braun), Albert-Schweitzer-Strasse 11, 03050 Cottbus. kay-p.braun@web.de
authors.forename: Kay-P
authors.initials: KP
authors.lastname: Braun
authors.forename: Sabine
authors.initials: S
authors.lastname: Brookman-Amissah
authors.forename: Katrin
authors.initials: K
authors.lastname: Geissler
authors.forename: Doris
authors.initials: D
authors.lastname: Ast
authors.forename: Matthias
authors.initials: M
authors.lastname: May
authors.forename: Helmut
authors.initials: H
authors.lastname: Ernst