title: Hormones and drinking behaviour: new findings on ghrelin, insulin, leptin and volume-regulating hormones. An ESBRA Symposium report.
abstract: There is growing evidence for a role of appetite-related peptides and volume-regulating hormones in alcoholism. In particular, recent evidence has suggested that hormones, such as ghrelin, insulin and leptin and volume-regulating hormones, could play a role in alcohol-seeking behaviour. The goal of this review is to discuss the results of recent preclinical and clinical investigations on this topic. The findings indicate that neuroendocrinological mechanisms are potentially involved in the neurobiology of alcohol craving. Accordingly, research on this topic could lead to possible development of new therapeutic approaches in the treatment of patients with alcohol problems.
authors.affiliation: Institute of Internal Medicine, Catholic University of Rome, Largo A. Gemelli 8, Rome, Italy. g.addolorato@rm.unicatt.it
authors.forename: Giovanni
authors.initials: G
authors.lastname: Addolorato
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Leggio
authors.forename: Thomas
authors.initials: T
authors.lastname: Hillemacher
authors.forename: Thomas
authors.initials: T
authors.lastname: Kraus
authors.forename: Elisabet
authors.initials: E
authors.lastname: Jerlhag
authors.forename: Stefan
authors.initials: S
authors.lastname: Bleich