title: [The box-dimension-based localization of neuronal structures in pallidotomy for treatment of Parkinson's disease].
abstract: Currently, the intraoperative location of microelectrode position in the globus pallidus is subjective and qualitative; it only depends on the experience of doctors during pallidotomy for the treatment of Parkinson's disease. The fractal characteristic of neuronal discharge signals is analyzed for target localization; the factor of box dimension is extracted from the microelectrode recordings for identifying the neuronal structures at the depth of microelectrode. New objective and quantitative targeting technique is presented by processing clinical microelelctrode recordings of Parkinson's disease. Through the validation of clinical data and the critical appraisal by experts, the targeting technique can be used for improving the accuracy of localization in neurosurgery.
authors.affiliation: Department of Biomedical Engineering, College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China. lxwlq2003@163.com
authors.forename: Xinwen
authors.initials: X
authors.lastname: Liu
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Qian
authors.forename: Huinan
authors.initials: H
authors.lastname: Wang
authors.forename: Tianming
authors.initials: T
authors.lastname: Yang
authors.forename: Kunshan
authors.initials: K
authors.lastname: Li