title: Efficient solvent- and metal-free Sonogashira protocol catalysed by 1,4-diazabicyclo(2.2.2) octane (DABCO).
abstract: An efficient metal-free Sonogashira coupling protocol catalysed by DABCO is reported, where very good conversions and selectivities to the cross-coupling product were obtained under mild reaction conditions. The reported solvent-, phosphane- and metal-free protocol, that uses a cheap base as catalyst, considerably improves the green credentials of the reaction.
authors.affiliation: Green Chemistry Centre of Excellence, The University of York, Heslington, York, UK YO10 5DD. q62alsor@uco.es
authors.forename: Rafael
authors.initials: R
authors.lastname: Luque
authors.forename: Duncan J
authors.initials: DJ
authors.lastname: Macquarrie