Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome.
In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy ((1)H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) (1)H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early (1)H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.
Aragão
Maria de Fátima Vasco
Mde F
Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA. aragao@truenet.com
Law
Meng
M
Netto
João Prola
JP
Valença
Marcelo Moraes
MM
Naidich
Thomas
T