Headspace solid phase micro extraction gas chromatographic determination of fenthion in human serum.
A simple and effective analytical procedure was developed for the determination of fenthion residues in human serum samples. The sample treatment was performed using the headspace solid-phase micro extraction with polyacrylate fiber, which has the advantage to require low amount of serum (1 mL) without tedious pre-treatment. The quantification of fenthion was carried out by gas chromatography-mass spectrometry and the recoveries ranged from 79 to 104% at two spiking levels for 6 replicates. Detection and quantification limits were calculated as 1.51 and 4.54 ng/mL of serum respectively. Two fenthion metabolites fenoxon and fenthion-sulfoxide were also identified.
Kasiotis
Konstantinos M
KM
Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.
Souki
Helen
H
Pharmacology Department, Medical School, University of Athens, 115 27, Athens, Greece.
Tsakirakis
Angelos N
AN
Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.
Carageorgiou
Haris
H
Pharmacology Department, Medical School, University of Athens, 115 27, Athens, Greece.
Theotokatos
Spiridon A
SA
Agroindustrial Robola Growers Cooperative of Kefalllinia, Omala, 28100 Kefallinia, Greece.
Haroutounian
Serkos A
SA
Chemistry Laboratory, Agricultural University of Athens, Iera Odos 75, 118 55, Athens, Greece.
Machera
Kyriaki
K
Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.