Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections.
We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%).
Legrand-Abravanel
Florence
F
Laboratoire de Virologie, Institut Fédératif de Biologie, TSA 40031, CHU Toulouse Purpan, Toulouse Cedex, France.
Thevenet
Isabelle
I
Mansuy
Jean-Michel
JM
Saune
Karine
K
Vischi
Françoise
F
Peron
Jean-Marie
JM
Kamar
Nassim
N
Rostaing
Lionel
L
Izopet
Jacques
J