title: Genetic testing of sperm donors: survey of current practices.
abstract: OBJECTIVE
  To determine which genetic tests are being performed on sperm donor applicants in the United States.
  
  
  METHODS
  An electronic survey was distributed to 26 sperm banks to evaluate their genetic testing practices.
  
  
  METHODS
  Sperm banks in the United States.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  None. Survey of current practices.
  
  
  METHODS
  Survey of current practices.
  
  
  RESULTS
  Cystic fibrosis (CF) carrier screening, chromosome analyses, and hemoglobin evaluations are performed on the majority of sperm donor applicants. Tay-Sachs disease carrier screening is performed on most donors with Jewish heritage but there is significant variation in screening for other disorders that occur with increased frequency in this population. Individual sperm banks use different laboratory tests for evaluation of the same conditions, with each test having different carrier detection rates and interpretations.
  
  
  CONCLUSIONS
  The genetic testing performed on sperm donors varies significantly at sperm banks across the United States. Therefore, recipients should be clearly informed about the specific evaluations performed on their donor of interest. Thus it is important that sperm banks employ genetic professionals to evaluate the donors' and recipients' medical histories and perform a genetic risk assessment. This will allow clients to make informed decisions about use of semen specimens from an anonymous sperm donor.
authors.affiliation: California Cryobank, Inc, Los Angeles, CA 90025, USA.
authors.forename: Charles A
authors.initials: CA
authors.lastname: Sims
authors.forename: Pamela
authors.initials: P
authors.lastname: Callum
authors.forename: Marilyn
authors.initials: M
authors.lastname: Ray
authors.forename: Jennifer
authors.initials: J
authors.lastname: Iger
authors.forename: Rena E
authors.initials: RE
authors.lastname: Falk