Synthesis of the pentacyclic core of lihouidine.
The pentacyclic base of the sponge-derived alkaloid lihouidine has been assembled from two quinoline fragments. The key step is a nitration-promoted cyclization to form the C-C bond between the two quinoline units.
Feldman
Ken S
KS
Chemistry Department, The Pennsylvania State University, University Park, PA 16802 USA.
Coca
Adiel
A