title: [Prevalence of cognitive deterioration in people over 80-years-old: COGMANLLEU study].
abstract: BACKGROUND
  We want to detect the prevalence of cognitive prevalence deterioration in the elderly population of 80-years-old or older, their grade of deterioration and the causal pathogenic entity.
  
  
  METHODS
  
  
  
  METHODS
  a cross-sectional population study, including a first phase of screening and a second one of diagnosis confirmation.
  
  
  METHODS
  a total of 877 elderly people of 80-years-old or older belonging to the basic health care area of Manlleu (Osona, Catalonia midlands). In the first phase, relatives and/or caregivers were interviewed, and the participating subjects underwent a set of tests. Those who obtained 24 points or less on the Mini-Mental State Examination (MMSE) and/or an equal Global Deterioration Scale (GDS) or over 3 were admitted to the second phase. During the second phase, a general and a neurological examination were performed, along with blood tests, cranial computed tomography scan and a neuropsychological study. DSM-IV criteria were used for dementia diagnosis, NINCDS-ADRA criteria for Alzheimer's disease (AD) and NINCS-AIREN for vascular dementia.
  
  
  RESULTS
  Half of the people over 80-years-old had cognitive deterioration. One-fourth had dementia. A total of 70.3% of these dementias corresponded to AD (47.2% AD without vascular lesions and 23.1% AD with vascular lesions) and 12% corresponded to vascular dementia. The percentage of other degenerative dementias was 17.6%. Age and gender were observed to be associated to dementia.
  
  
  CONCLUSIONS
  The prevalence of dementia in the COGMANLLEU study is similar to other European studies. AE is the most frequent dementia.
authors.affiliation: Servicio de Neurología, Consorci Hospitalari, Hospital General de Vic, Vic, Barcelona. ebufill@auna.com
authors.forename: E
authors.initials: E
authors.lastname: Bufill
authors.forename: A
authors.initials: A
authors.lastname: Bartés
authors.forename: A
authors.initials: A
authors.lastname: Moral
authors.forename: T
authors.initials: T
authors.lastname: Casadevall
authors.forename: M
authors.initials: M
authors.lastname: Codinachs
authors.forename: E
authors.initials: E
authors.lastname: Zapater
authors.forename: J C
authors.initials: JC
authors.lastname: Rovira
authors.forename: R
authors.initials: R
authors.lastname: Pérez
authors.forename: P
authors.initials: P
authors.lastname: Roura
authors.forename: R
authors.initials: R
authors.lastname: Blesa