title: Trends in transfusion-transmitted viral infections from 2001 to 2006 in Ibadan, Nigeria.
abstract: OBJECTIVE
  Screening of blood before transfusion is an effective strategy to reduce transfusion-transmitted viruses. However, reports on viral marker trends among the donor population are scarce. This study looked at trends in the seroprevalence of hepatitis B (HBV) and C (HCV) and human immunodeficiency virus (HIV).
  
  
  METHODS
  This is a retrospective study among blood donors at a tertiary hospital in Nigeria. We used the blood bank records to calculate yearly seroprevalence rates for HBV, HCV and HIV per 100 donations from 2001 to 2006.
  
  
  RESULTS
  A total of 33,682 prospective donors were screened, of which 13.2% were positive for HBsAg. The overall seroprevalence rates for HIV and HCV were 7.66% and 3.69%, respectively. HIV seroprevalence rose from 4.25% in 2001 to peak at 12.64% in 2003, before a steep drop to 6.35% in 2004 and a gradual decline to 5.70% in 2006 (p < 0.05).
  
  
  CONCLUSIONS
  The seroprevalence rates for HIV and HBsAg fluctuated greatly during the study period while the seroprevalence of HCV was consistent. The screening kits used may be partly responsible for these fluctuations. Innovative programs for donor education, with the use of a formal questionnaire in donor selection, are recommended to ensure a safe donor population.
authors.affiliation: Department of Haematology, Medical Statistics and Environmental Health, College of Medicine, University of Ibadan, Ibadan, Nigeria. folukefasola@yahoo.com
authors.forename: Foluke A
authors.initials: FA
authors.lastname: Fasola
authors.forename: Taiwo R
authors.initials: TR
authors.lastname: Kotila
authors.forename: Joshua O
authors.initials: JO
authors.lastname: Akinyemi