One-pot formation of large macrocycles with modifiable peripheries and internal cavities.
The shape of things to come: Aromatic oligohydrazide macrocycles with planar backbones enforced by three-center hydrogen bonds are formed in high yield from monomeric diacid chlorides and dihydrazides. Macrocycles consisting of six meta-linked pyridine and benzene residues have an internal cavity of about 10 A diameter, while those with alternating meta- and para-linked benzene residues are larger and contain multiple convergent sites (see picture).
Ferguson
Joseph S
JS
Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
Yamato
Kazuhiro
K
Liu
Rui
R
He
Lan
L
Zeng
Xiao Cheng
XC
Gong
Bing
B