First evidence of association between G72 and bipolar disorder in the Chinese Han population.
The G72/G30 (D-amino-acid oxidase activator) complex was the first gene to be associated with bipolar disorder (BPD) in European populations, but until now no such association has been identified in Asian populations. To investigate possible association in the Chinese Han population, we carried out a study involving 475 BPD patients and 588 healthy controls. The results provide first evidence for the single nucleotide polymorphism rs778293 in G72 as a potential candidate in altering risk for BPD in the Chinese Han population.
Zhang
Zhao
Z
Changing Institute of Mental Health, Institute of Neuropsychiatric Science and Systems Biological Medicine, Xiehe Road 299, Bio-X Center Hospital, Bio-X Center, Shanghai Jiao Tong University, Shanghai, PR China.
Li
You
Y
Zhao
Qian
Q
Huang
Ke
K
Wang
Peng
P
Yang
Ping
P
Li
Sheng
S
Feng
Guoyin
G
Lindpaintner
Klaus
K
He
Lin
L
Shi
Yongyong
Y