title: Comparison of laparoscopy-assisted and open pylorus-preserving pancreaticoduodenectomy for periampullary disease.
abstract: BACKGROUND
  Although many reports have described laparoscopic pancreatic surgery, pancreaticoduodenectomy (PD) has not been widely accepted. The present study aimed to compare laparoscopy-assisted and open pylorus-preserving pancreaticoduodenectomy (PPPD) to investigate the feasibility, safety, and tumor clearance.
  
  
  METHODS
  Fifteen patients with periampullary disease underwent laparoscopy-assisted PPPD, in which resection was performed laparoscopically and the reconstruction was performed through a small midline incision. These patients were compared with 15 patients who, during the same period, underwent conventional open PPPD.
  
  
  RESULTS
  Mean operative time and mean blood loss were similar between groups. No significant differences in the incidence of complications or hospital stay were noted between groups. Surgical margin and number of lymph nodes found in the resected specimen did not differ between groups.
  
  
  CONCLUSIONS
  Laparoscopy-assisted PPPD is on the same level with conventional open surgery in terms of perioperative outcomes or treatment efficacy.
authors.affiliation: Division of Gastroenterological Surgery, Chiba Cancer Center Hospital, Chiba, Japan. acho@chiba-cc.jp
authors.forename: Akihiro
authors.initials: A
authors.lastname: Cho
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Matsuo
authors.initials: M
authors.lastname: Nagata
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takiguchi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Shimada
authors.forename: Osamu
authors.initials: O
authors.lastname: Kainuma
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Souda
authors.forename: Hisashi
authors.initials: H
authors.lastname: Gunji
authors.forename: Akinari
authors.initials: A
authors.lastname: Miyazaki
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ikeda
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tohma
authors.forename: Ikuko
authors.initials: I
authors.lastname: Matsumoto