title: Molecular imaging targeting peptide receptors.
abstract: Overexpressed neuropeptide receptors allow tumor visualization using e.g. radiolabeled peptidic receptor ligands and positron emission tomography (PET) or single photon emission computed tomography (SPECT). This review summarizes the development of radiolabeled probes for peptide receptor imaging since the emergence of the technology with a particular focus on peptide radiopharmaceuticals developed during the last 5 years, and highlights the different factors which are decisive during the process of tracer development and evaluation.
authors.affiliation: Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, D-81675 München, Germany. M.Schottelius@lrz.tum.de
authors.forename: Margret
authors.initials: M
authors.lastname: Schottelius
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Wester