Hemophagocytic syndrome: a cause for fatal outcome in tuberculosis.
Hemophagocytic syndrome is rare syndrome characterized by unregulated proliferation and activation of macrophages and phagocytosis of the platelet, erythrocytes, lymphocytes and their hematopoietic precursors in the bone marrow, resulting in cytopenias. It is associated with stimuli-like infections, malignancies and immunocompromised states. We present here a case of generalized lymphadenopathy, hepatosplenomegaly and progressive cytopenias in a 17-year-old male.
Gupta
Anupama P
AP
Department of Pathology, Government Medical College, Nagpur, India. pama_gpta@rediffmail.com
Parate
S N
SN
Bobhate
S K
SK