Insertion/deletion polymorphism of the bradykinin type 2 receptor gene influence diastolic blood pressure.
The contribution of kinins to the beneficial effects in cardiovascular risk reductions remains unclear. In this context, the present study examined whether the +9 bp/-9 bp polymorphism in bradykinin type 2 receptor gene, predicts hypertension risk in a large urban Brazilian population. Our finding indicated that the -9 bp allele may contribute to hypertension because of increased diastolic pressure.
Freitas
S R
SR
Pereira
A C
AC
Floriano
M S
MS
Mill
J G
JG
Krieger
J E
JE