title: Synthesis and biological evaluation of technetium-labeled D-glucose-MAG3 derivative as agent for tumor diagnosis.
abstract: A d-glucose-MAG(3) derivative was successfully synthesized and radiolabeled in high labeling yield. Biodistribution studies in Ehrlich tumor-bearing mice were performed. This compound showed high accumulation in tumor tissue with high tumor-to-muscle ratio and moderate tumor-to-blood ratio. Thus, d-glucose-MAG(3) is a potential agent for tumor diagnosis.
authors.affiliation: Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31279-901 Belo Horizonte, Minas Gerais, Brazil.
authors.forename: André Luís Branco
authors.initials: AL
authors.lastname: de Barros
authors.forename: Valbert Nascimento
authors.initials: VN
authors.lastname: Cardoso
authors.forename: Luciene das Graças
authors.initials: Ld
authors.lastname: Mota
authors.forename: Elaine Amaral
authors.initials: EA
authors.lastname: Leite
authors.forename: Mônica Cristina de
authors.initials: MC
authors.lastname: Oliveira
authors.forename: Ricardo José
authors.initials: RJ
authors.lastname: Alves