title: Postcholecystectomy syndrome - an algorithmic approach.
abstract: OBJECTIVE
  The postcholecystectomy syndrome includes a heterogeneous group of diseases, usually presenting as abdominal symptoms following gallbladder removal. The clinical management of these patients is frequently without an evidence-based approach.
  
  
  METHODS
  We evaluated 80 patients with postcholecystectomy problems consecutively admitted during a period of 36 months. The liver function tests (LFTs) assessment and transabdominal ultrasound (TUS) were followed by endoscopic ultrasound (EUS). Endoscopic retrograde cholangio-pancreatography (ERCP) was then performed depeding on the results. With knowledge of the final diagnosis, the probable evaluation and outcomes were reassessed assuming that ERCP would have been performed as the initial procedure. Final diagnosis was confirmed by a combination of imaging findings, as well as clinical follow-up of 6 months.
  
  
  RESULTS
  In 53 patients biliary or pancreatic diseases were diagnosed: common bile duct stones, chronic pancreatitis, pancreatic cancer, papillary tumors, cholangiocarcinoma, insufficient cholecystectomy or sphincter of Oddi dysfunction. The other 27 patients had non-biliary symptoms (dyspepsia, IBS, etc.) and were consequently managed according to the symptoms. The sensitivity and specificity of EUS were high in the subgroup of patients with biliary or pancreatic symptoms (96.2% and 88.9%) and helped to indicate subsequent ERCP.
  
  
  CONCLUSIONS
  An algorithmic approach which used EUS for the initial evaluation of the patients with postcholecystectomy problems decreased the number of ERCPs by 51%, having as a consequence a decreased morbidity and mortality in this group of patients.
authors.affiliation: Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania. monalisafilip@yahoo.com
authors.forename: Monalisa
authors.initials: M
authors.lastname: Filip
authors.forename: Adrian
authors.initials: A
authors.lastname: Saftoiu
authors.forename: Carmen
authors.initials: C
authors.lastname: Popescu
authors.forename: Dan Ionut
authors.initials: DI
authors.lastname: Gheonea
authors.forename: Sevastita
authors.initials: S
authors.lastname: Iordache
authors.forename: Larisa
authors.initials: L
authors.lastname: Sandulescu
authors.forename: Tudorel
authors.initials: T
authors.lastname: Ciurea