Mitochondria and cancer.
The authors review the role played by mutations in mitochondrial DNA and in nuclear genes encoding mitochondrial proteins in cancer development, with an emphasis on the alterations of the oxidative phosphorylation system and glycolysis.
Máximo
Valdemar
V
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal.
Lima
Jorge
J
Soares
Paula
P
Sobrinho-Simões
Manuel
M