Structure elucidation at the nanomole scale. 2. Hemi-phorboxazole A from Phorbas sp.
Hemi-phorboxazole A, a minor truncated analogue of phorboxazole A from the marine sponge Phorbas sp., was isolated in a total yield of 16.5 microg (28 nmol). The structure was elucidated by application of integrated nanomole-scale natural product techniques, including cryomicroprobe NMR, (1)H-coupled HSQC, and circular dichroism (CD).
Dalisay
Doralyn S
DS
Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
Molinski
Tadeusz F
TF