title: Sarcoid-like granulomas in common variable immunodeficiency.
abstract: Common variable immunodeficiency (CVID) is a disorder characterized by hypogammaglobulinemia, poor antibody responses and recurrent bacterial infections. CVID patients have a higher prevalence of autoimmune disease and some of them develop noncaseating granulomas of the lungs, spleen, liver, skin, lymph nodes and eye. We report herein a 5-year-old girl with CVID presented with cutaneous nodules, granulomatous uveitis and oligoarthritis. The lesions, arthritis and uveitis responded well to treatment with the systemic administration of steroid. Different autoimmune diseases could be seen together in children with CVID. These patients require therapeutic cooperation of the immunologists with different specialists, including dermatologists, rheumatologists and ophthalmologists.
authors.affiliation: Department of Pediatrics, Division of Immunology and Allergy, Selcuk University Meram Medical Faculty, Konya, Turkey. hasibeartac@yahoo.com
authors.forename: Hasibe
authors.initials: H
authors.lastname: Artac
authors.forename: Banu
authors.initials: B
authors.lastname: Bozkurt
authors.forename: Beril
authors.initials: B
authors.lastname: Talim
authors.forename: Ismail
authors.initials: I
authors.lastname: Reisli