title: Asymmetric generation of fluorine-containing quaternary carbons adjacent to tertiary stereocenters: uses of fluorinated methines as nucleophiles.
abstract: Organocatalytic asymmetric Michael reactions of fluorinated nucleophiles with nitroolefins catalyzed by Cinchona alkaloid-derived thiourea catalysts generated the desired Michael products containing vicinal fluorinated quaternary and tertiary chiral centers with exceptional enantioselectivity.
authors.affiliation: Department of Chemistry, National University of Singapore, Singapore, Republic of Singapore.
authors.forename: Xiao
authors.initials: X
authors.lastname: Han
authors.forename: Jie
authors.initials: J
authors.lastname: Luo
authors.forename: Chen
authors.initials: C
authors.lastname: Liu
authors.forename: Yixin
authors.initials: Y
authors.lastname: Lu