Gastric and colonic mantle cell lymphoma - incidental discovery.
A 65-year old patient, with no medical history, was admitted for lower gastrointestinal bleeding. On clinical examination the patient seemed to be in good health. However the examination was completed with a rectosigmoidoscopy revealing the presence of mucosal erosions, ulcerations, multiple papulae. The histopathological examination raised the suspicion of a colonic lymphoma. Gastric biopsies suggested a gastric MALT type lymphoma associated to the colonic lymphoma, but the immunohistochemical profile corresponded to a mantle cell lymphoma. In spite of the general poor prognosis of mantle cell lymphoma, our patient had a good clinical and endoscopic response to the standard cyclophosphamide, vincristine, prednisone (CVP) therapy. The cases of gastric and colonic mantle lymphoma are rare, the response to therapy is poor; fortunately, our patient had a complete resolution after completion of the six cycles of chemotherapy.
Pitigoi
Dan
D
Department of Gastroenterology, Fundeni Clinical Institute; Bucharest, Romania. pitigoidancristian@yahoo.com
Stoica
Victor
V
Stoia
Razvan
R
Dobrea
Camelia
C
Becheanu
Gabriel
G
Diculescu
Mircea
M