title: On extremum seeking in bioprocesses with multivalued cost functions.
abstract: Finding optimal operating modes for bioprocesses has been, for a long time, a relevant issue in bioengineering. The problem is of special interest when it implies the simultaneous optimization of competing objectives. In this paper, we address the problem of finding optimal steady states that achieve the best tradeoff between yield and productivity by using nonmodel-based extremum-seeking control with semiglobal practical stability and convergence properties. A special attention is paid to processes with multiple steady states and multivalued cost functions.
authors.affiliation: Center for Systems Engineering and Applied Mechanics, Dept.of Mathematical Engineering, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium. bastin@inma.ucl.ac.be
authors.forename: Georges
authors.initials: G
authors.lastname: Bastin
authors.forename: Dragan
authors.initials: D
authors.lastname: Nesić
authors.forename: Ying
authors.initials: Y
authors.lastname: Tan
authors.forename: Iven
authors.initials: I
authors.lastname: Mareels