title: Anti-Ku autoantibodies: series of 5 cases.
abstract: Autoantibodies directed against nuclear protein Ku are infrequently detected. If present, they are found in high titers in patients with connective tissue overlap syndromes. This article describes 5 patients with anti-Ku antibodies in whom systemic lupus erythematosus, Sjögren's syndrome, idiopathic lung fibrosis or scleroderma - polymyositis overlap syndrome were diagnosed. Interestingly, signs and symptoms of transient cranial neuropathy involving trigeminal and facial nerves were reported by 3 patients. Cranial nerve neuropathy has not been described in patients with anti-Ku autoantibodies previously.
authors.affiliation: Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland. grykry@mp.pl
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Gryga
authors.forename: Mamert
authors.initials: M
authors.lastname: Milewski
authors.forename: Marek
authors.initials: M
authors.lastname: Zółciński
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dyczek
authors.forename: Jacek
authors.initials: J
authors.lastname: Musiał