title: Use of myocutaneous flaps for perineal closure following abdominoperineal excision of the rectum for adenocarcinoma.
abstract: BACKGROUND
  Abdominoperineal excision (APE) following radiotherapy is associated with a high rate of perineal wound complications. The use of myocutaneous flaps may improve wound healing. We present our experience using myocutaneous flaps for immediate reconstruction.
  
  
  METHODS
  Prospective data were collected on patients undergoing APE from October 2003 to December 2008. Patient demographics, operating time, wound complications and length of stay were recorded.
  
  
  RESULTS
  Fifty-one patients underwent APE for rectal adenocarcinoma, 21 had primary closure and 30 had myocutaneous flap closure (24 VRAM, 6 gracilis). The proportion of patients undergoing preoperative radiotherapy in each group were 62% and 93% respectively (P = 0.011). There were no major complications following primary closure of the unirradiated perineum. Major perineal wound complications requiring reoperation or debridement were seen in three (14%) patients following primary closure and five (17%) patients with flap closure. After radiotherapy, closure with a flap reduced the length of stay from 20 to 15 days, but this difference was not statistically significant (P = 0.36).
  
  
  CONCLUSIONS
  The use of flap closure in irradiated patients is associated with fewer perineal complications and a shorter hospital stay.
authors.affiliation: Department of General Surgery, St Thomas' Hospital, London, UK. shirley.chan@talk21.com
authors.forename: S
authors.initials: S
authors.lastname: Chan
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: R
authors.initials: R
authors.lastname: Ng
authors.forename: D
authors.initials: D
authors.lastname: Ross
authors.forename: P
authors.initials: P
authors.lastname: Roblin
authors.forename: E
authors.initials: E
authors.lastname: Carapeti
authors.forename: A B
authors.initials: AB
authors.lastname: Williams
authors.forename: M L
authors.initials: ML
authors.lastname: George