title: Genome halving with double cut and join.
abstract: The genome halving problem, previously solved by El-Mabrouk for inversions and reciprocal translocations, is here solved in a more general context allowing transpositions and block interchange as well, for genomes including multiple linear and circular chromosomes. We apply this to several datasets and compare the results to the previous algorithm.
authors.affiliation: School of Information Technology and Engineering, University of Ottawa, 800 King Edward Avenue, Ottawa, Ontario, K1N 6N5, Canada. rwarr059@uottawa.ca
authors.forename: Robert
authors.initials: R
authors.lastname: Warren
authors.forename: David
authors.initials: D
authors.lastname: Sankoff