What the neuron tells glia.
Astrocytic processes at the synapse contribute to neurotransmission, but we understand little about their formation and differentiation. In this issue of Neuron, Yang et al. show that presynaptic input induces expression of the predominant glial transporter involved in glutamate clearance, and this induction involves the transcription factor kappa B-binding protein.
Edwards
Robert
R
Department of Neurology, University of California, San Francisco, School of Medicine, San Francisco, CA 94158, USA. robert.edwards@ucsf.edu