title: Catalytic enantioselective construction of all-carbon quaternary stereocenters by an organocatalytic Diels-Alder reaction of alpha-substituted alpha,beta-unsaturated aldehydes.
abstract: A binaphthyl-based primary amine (R)- was designed for the Diels-Alder reaction of alpha-substituted alpha,beta-unsaturated aldehydes; in the presence of the TfOH salt of (R)-, the Diels-Alder reaction of alpha-substituted alpha,beta-unsaturated aldehydes with cyclopentadiene proceeded to afford the corresponding cycloadducts having one all-carbon quaternary stereocenter in good yield with good to high stereoselectivity.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.
authors.forename: Taichi
authors.initials: T
authors.lastname: Kano
authors.forename: Youhei
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Kenta
authors.initials: K
authors.lastname: Osawa
authors.forename: Taiga
authors.initials: T
authors.lastname: Yurino
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka