title: Diagnosis and management of acquired pure red cell aplasia.
abstract: Pure red cell aplasia is a syndrome characterized by a severe normocytic anemia, reticulocytopenia, and absence of erythroblasts from an otherwise normal bone marrow. Although the causes and natural course of this syndrome are variable and although the anemia in some patients can be managed by treatment of an underlying inflammatory or neoplastic disease, the pathogenesis of a large number of cases is autoimmune, including those associated with thymoma, and are best managed with immunosuppressive therapy.
authors.affiliation: Division of Hematology, Department of Medicine, Akita University School of Medicine, Hondo 1-1-1, Akita 018-8543, Japan. ksawada@doc.med.akita-u.ac.jp
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sawada
authors.forename: Makoto
authors.initials: M
authors.lastname: Hirokawa
authors.forename: Naohito
authors.initials: N
authors.lastname: Fujishima