BMP6 orchestrates iron metabolism.
The small liver peptide hepcidin is a major regulator of systemic iron homeostasis in mammals, adapting iron absorption to the body's demands. Two new studies now identify BMP6 as the key endogenous regulator of hepcidin.
Camaschella
Clara
C
Università Vita-Salute & Istituto Scientifico San Raffaele, Division of Genetics and Cell Biology, Milano, Italy. camaschella.clara@hsr.it