Tracking bio-molecules in live cells using quantum dots.
Single particle tracking (SPT) techniques were developed to explore bio-molecules dynamics in live cells at single molecule sensitivity and nanometer spatial resolution. Recent developments in quantum dots (Qdots) surface coating and bio-conjugation schemes have made them most suitable probes for live cell applications. Here we review recent advancements in using quantum dots as SPT probes for live cell experiments.
Chang
Yun-Pei
YP
Department of Chemistry and Biochemistry, University of California at Los Angeles, 607 Charles Young Drive, East Los Angeles, California 90095-1569, USA. ypchang@chem.ucla.edu
Pinaud
Fabien
F
Antelman
Joshua
J
Weiss
Shimon
S