[Apoprotein E and its availability in clinical physiology].
Apoprotein E is a structural component of serum lipoproteins and relates to regulative apoproteins. This protein participates in fatty acids transportation to cells and in cholesterol transport to liver. In paper it has been considered the physiological role apoE in metabolical mechanisms of serum lipids in normal condition and in different pathology and especially the participation of apoE in nerve cells reparation and free radical oxidation processes. It has been analyzed the polymorphism of apoE genes in human population and risk of development of hyperlipidemia and cardio-vascular diseases. It has been discussed the possible availability to use of his biological marker in clinical chemistry.
Boĭko
E R
ER
Kaneva
A M
AM