[Etiology, diagnosis, and treatment of lower limb arterial occlusion in patients below 45 years old].
OBJECTIVE
To evaluate the etiology, diagnosis, and treatment of lower limb arterial occlusion in patients below 45 years old.


METHODS
The clinical data of 58 patients with lower limb arterial occlusion (except for Buerger's disease) below 45 years old admitted to PUMC Hospital from July 1997 to November 2007 were retrospectively analyzed.


RESULTS
Among these 58 patients, 31 patients (53.4%) had confirmed thrombophilic risk factors, including 12 patients had two or more thrombophilic risk factors. Follow-up (ranged 2-43 months, mean 10 months) showed higher rates of revascularization and amputation in patients with thrombophilic risk factors (22.6% and 22.6%, respectively) than in those without thrombophilic risk factors (14.8% and 11.1%, respectively) (P > 0.05). Among patients with two or more thrombophilic risk factors, the rates of revascularization and amputation were 25.0% and 33.3%, respectively.


CONCLUSIONS
Lower limb arterial occlusion in young adults is often caused by thrombophilic risk factors. Attention should be taken to identify these etiologies before surgical treatment.
Tang
Feng
F
Department of Vascular Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100032, China.
Liu
Chang-Wei
CW
Guan
Heng
H
Li
Yong-Jun
YJ
Zheng
Yue-Hong
YH
Ye
Wei
W
Liu
Bao
B