Electron relay race in peptides.
A peptide assay was developed that allows the measurement of electron-transfer (ET) efficiencies in peptides. It turns out that two-step ET processes are faster than single-step reactions. This requires relay amino acids with appropriate redox potentials. Not only aromatic but also sulfur-containing aliphatic amino acids can act as stepping stones for the charge. With tryptophan, histidine, and cysteine the reaction is a more complex proton-coupled ET.
Giese
Bernd
B
Universität Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland. bernd.giese@unibas.ch
Wang
Min
M
Gao
Jian
J
Stoltz
Moritz
M
Müller
Pavel
P
Graber
Michael
M