Ultrasound-promoted access to Baylis-Hillman amines.
It is surveyed that the amination of the Baylis-Hillman acetates with primary amines can be dramatically promoted in improved yields and shortened reaction time under ultrasound irradiation than those under conventional stirring. The extensive scope of both amines and acetates are screened to investigate the relationship between substituents and their performance in such transformation.
Ge
Shao-Qin
SQ
Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, PR China.
Hua
Yun-Yu
YY
Xia
Min
M