title: Fluorescent recognition of potassium and calcium ions using functionalised CdSe / ZnS quantum dots.
abstract: Schiff base receptor 1a has been synthesised and attached to the surface of preformed CdSe/ZnS Quantum Dots (QDs) to form QD-conjugate 2a. While 1a was determined to be selective for Mg2+, 2a demonstrated selectivity for both K+ and Ca2+ when tested against a range of physiologically and environmentally relevant cations by changes in the fluorescence spectra. Thus, the nanoparticle surface functions as a scaffold for the organisation of receptors enabling semi-selective binding. The fluorescence response was shown to be linear between 15-50 microM for K+ and 2-35 microM for Ca2+. It was also demonstrated that 2a could measure both K+ and / or Ca2+ in solutions containing both ions.
authors.affiliation: School of Pharmacy and Life Sciences, The Robert Gordon University, Aberdeen AB10 1FR, UK.
authors.forename: Narinder
authors.initials: N
authors.lastname: Singh
authors.forename: Ray C
authors.initials: RC
authors.lastname: Mulrooney
authors.forename: Navneet
authors.initials: N
authors.lastname: Kaur
authors.forename: John F
authors.initials: JF
authors.lastname: Callan