title: Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome.
abstract: In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy ((1)H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) (1)H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early (1)H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.
authors.affiliation: Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA. aragao@truenet.com
authors.forename: Maria de Fátima Vasco
authors.initials: Mde F
authors.lastname: Aragão
authors.forename: Meng
authors.initials: M
authors.lastname: Law
authors.forename: João Prola
authors.initials: JP
authors.lastname: Netto
authors.forename: Marcelo Moraes
authors.initials: MM
authors.lastname: Valença
authors.forename: Thomas
authors.initials: T
authors.lastname: Naidich