title: From working memory to epilepsy: dynamics of facilitation and inhibition in a cortical network.
abstract: Persistent states are believed to be the correlate for short-term or working memory. Using a previously derived model for working memory, we show that disruption of the lateral inhibition can lead to a variety of pathological states. These states are analogs of reflex or pattern-sensitive epilepsy. Simulations, numerical bifurcation analysis, and fast-slow decomposition are used to explore the dynamics of this network.
authors.affiliation: University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
authors.forename: Sergio
authors.initials: S
authors.lastname: Verduzco-Flores
authors.forename: Bard
authors.initials: B
authors.lastname: Ermentrout
authors.forename: Mark
authors.initials: M
authors.lastname: Bodner