title: Seronegative autoimmune hepatitis presenting after diagnosis of coeliac disease: a case report.
abstract: The relationship between liver dysfunction and coeliac disease is well established, ranging from transaminitis to chronic liver disease. In this report, we describe for the first time the development of a 'seronegative' autoimmune hepatitis in a teenager previously diagnosed with coeliac disease. He had normal liver function tests (LFTs) at diagnosis and was strictly compliant with a gluten-free diet. On screening blood tests at 1 year post diagnosis, he presented with raised LFTs leading to a diagnosis of autoimmune hepatitis on liver biopsy, successfully treated with mycophenolate mofetil. By using screening LFTs, we may well have prevented this patient from developing disease complications.
authors.affiliation: Department of Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Quail
authors.forename: Richard K
authors.initials: RK
authors.lastname: Russell
authors.forename: Chris
authors.initials: C
authors.lastname: Bellamy
authors.forename: Giorgina
authors.initials: G
authors.lastname: Mieli-Vergani
authors.forename: Peter M
authors.initials: PM
authors.lastname: Gillett