GetBonNie for building, analyzing and sharing rule-based models.
CONCLUSIONS
GetBonNie is a web-based application for building, analyzing and sharing rule-based models encoded in the BioNetGen language (BNGL). Tools accessible within the GetBonNie environment include (i) an applet for drawing graphs that correspond to BNGL code; (ii) a network-generation engine for translating a set of rules into a chemical reaction network; (iii) simulation engines that implement generate-first, on-the-fly and network-free methods for simulating rule-based models; and (iv) a database for sharing models, parameter values, annotations, simulation tasks and results.


BACKGROUND
GetBonNie is free at (http://getbonnie.org).
Hu
Bin
B
Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA.
Matthew Fricke
G
G
Faeder
James R
JR
Posner
Richard G
RG
Hlavacek
William S
WS