title: Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome.
abstract: Joubert syndrome is a rare autosomal recessive disease characterized by hypotonia, ataxia, episodic hyperpnea, psychomotor retardation, abnormal ocular movements, cerebellar vermian hypoplasia, and molar tooth sign on magnetic resonance imaging. Neuroleptic malignant syndrome is an uncommon and potentially fatal idiosynchratic reaction of antipsychotic drugs, in which the clinical scenario encompass muscular rigidity, hyperthermia, autonomic dysfunction, altered consciousness, high creatinine phosphokinase levels, and leukocytosis. This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome.
authors.affiliation: Department of Pediatrics, Gulhane Military Medical Academy, Ankara, Turkey. sebahattinvurucu@yahoo.com
authors.forename: Sebahattin
authors.initials: S
authors.lastname: Vurucu
authors.forename: Ayhan
authors.initials: A
authors.lastname: Congologlu
authors.forename: Demet
authors.initials: D
authors.lastname: Altun
authors.forename: Bulent
authors.initials: B
authors.lastname: Unay
authors.forename: Ridvan
authors.initials: R
authors.lastname: Akin