title: The diagnostic hurdle of an elderly male with bone pain: how 18F-FDG-PET led to diagnosis of a leiomyosarcoma of the adrenal gland.
abstract: It is uncommon for patients to present with bone metastases while the primary tumor is still unknown. The case of a patient with bone metastases as primary presentation of leiomyosarcoma, who was diagnosed after a 18F-FDG PET-CT and a CT-guided biopsy of the adrenal gland is described. If after routine physical, laboratory and radiological investigations no diagnosis can be made, 18F-FDG PET should be added to the conventional work-up of patients with unknown primary cancer. In this way, unnecessary and enduring suffering of symptomatic patients may be prevented.
authors.affiliation: Department of Medical Oncology, Radboud University Nijmegen Medical Centre, The Netherlands. h.vanlaarhoven@onco.umcn.nl
authors.forename: Hanneke W M
authors.initials: HW
authors.lastname: Van Laarhoven
authors.forename: Maarten
authors.initials: M
authors.lastname: Vinken
authors.forename: Roel
authors.initials: R
authors.lastname: Mus
authors.forename: Uta
authors.initials: U
authors.lastname: Flucke
authors.forename: Wim J G
authors.initials: WJ
authors.lastname: Oyen
authors.forename: Winette T
authors.initials: WT
authors.lastname: Van der Graaf