[The serum levels of a soluble form of HLA I molecules in patients with lung cancer].
The paper presents the results of studying the content of soluble HLA I (sHLA-I) molecules in the blood samples from 56 patients first admitted to hospital for histologically verified lung cancer and 23 healthy donors matched by the patients' sex and age. The findings suggest that the development of Stages IB, IIA, and IIIA lung cancer is accompanied by a significant reduction in the serum levels of sHLA-I molecules. The serum concentration of sHLA-I molecules is decreased when the involvement foci are located in the lymph nodes of the lung root or in the mediastinum, but significantly increased when distant metastases emerge. The different morphological variants of the structure of a tumor do not differ in the serum content of sHLA molecules in the patients.
Pegov
R G
RG
Aliasova
A V
AV
Novikov
V V
VV
Baryshnikov
A Iu
AIu