[Treatment of pemphigus with rituximab].
Pemphigus is a life-threatening autoimmune blistering disease affecting the skin and mucosa. Patients with severe pemphigus require long-term treatment with corticosteroids and other immunosuppressive drugs, which can lead to serious adverse events. Rituximab, a monoclonal antibody directed against the CD20 antigen of B lymphocytes, has been demonstrated to be effective in recalcitrant and life-threatening pemphigus.
Li
Jun
J
Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. lijun35@hotmail.com
Zheng
He-Yi
HY
Liu
Yue-Hua
YH