title: Oxylipins from Dracontium loretense.
abstract: Four novel oxylipins (1-4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMS(n)) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear (2,3)J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, SA, Italy.
authors.forename: Angelyne
authors.initials: A
authors.lastname: Benavides
authors.forename: Assunta
authors.initials: A
authors.lastname: Napolitano
authors.forename: Carla
authors.initials: C
authors.lastname: Bassarello
authors.forename: Virginia
authors.initials: V
authors.lastname: Carbone
authors.forename: Patrizia
authors.initials: P
authors.lastname: Gazzerro
authors.forename: Annamaria
authors.initials: A
authors.lastname: Malfitano
authors.forename: Paola
authors.initials: P
authors.lastname: Saggese
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bifulco
authors.forename: Sonia
authors.initials: S
authors.lastname: Piacente
authors.forename: Cosimo
authors.initials: C
authors.lastname: Pizza