title: Brain activation during the spot the differences game.
abstract: Spot the Differences is a simple and popular game in which an observer compares a pair of similar pictures to detect the differences between them. Functional activation of the brain while playing this game has not been investigated. We used functional magnetic resonance imaging to investigate the main cortical regions involved in playing this game and compared the sites of cortical activation between a session of playing the game and a session of viewing 2 identical pictures. The right posterior parietal cortex showed more activation during game playing, and cortical activation volume correlated with game-playing accuracy. This cortical region may play an important role in awareness of differences between 2 similar pictures.
authors.affiliation: Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan. estima4106@yahoo.co.jp
authors.forename: Eiji
authors.initials: E
authors.lastname: Fukuba
authors.forename: Hajime
authors.initials: H
authors.lastname: Kitagaki
authors.forename: Akihiko
authors.initials: A
authors.lastname: Wada
authors.forename: Kouji
authors.initials: K
authors.lastname: Uchida
authors.forename: Shinji
authors.initials: S
authors.lastname: Hara
authors.forename: Takafumi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Kazushige
authors.initials: K
authors.lastname: Oda
authors.forename: Nobue
authors.initials: N
authors.lastname: Uchida