title: Enhancement of a catalysis-based fluorometric detection method for palladium through rational fine-tuning of the palladium species.
abstract: Metal analyses in chemistry, materials science, and environmental science are currently performed using techniques such as inductively coupled plasma mass spectrometry and X-ray fluorescence, which require expensive instrumentation and are not high-throughput. Although fluorescent probes are known for their sensitivity and specificity and are amenable to high-throughput analyses, the robustness of such analyses are typically limited due to their binding-based nature. Herein we report an improvement of our previously reported catalysis-based fluorescent probe for palladium by rationally fine-tuning the redox and coordination chemistries of the palladium species involved in the O-deallylation reaction. This method now rivals current analytical methods with respect to sensitivity. We demonstrate palladium detection in various active pharmaceutical ingredients, spent catalytic converter materials, and a metal scavenger resin. Thus, fluorescent methods may have the potential for substituting the current instrument-intensive techniques.
authors.affiliation: Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, USA.
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Garner
authors.forename: Fengling
authors.initials: F
authors.lastname: Song
authors.forename: Kazunori
authors.initials: K
authors.lastname: Koide