title: Development of gastro-lymphatic fistula during chemoradiotherapy for advanced esophageal cancer: a case report.
abstract: This is a case report of a gastro-lymphatic fistula which appeared during chemoradiotherapy for advanced esophageal cancer. A 60-year-old male was referred to the University of the Ryukyus Hospital because of a 10 kg monthly weight loss and dysphagia. Computed tomography (CT) scans indicated thickened esophageal wall at the lower thoracic esophagus and a swollen lymph node attached to the lesser curvature of the stomach. Histological analysis of the biopsy specimen revealed poorly differentiated squamous cell carcinoma and the diagnosis was of advanced esophageal cancer. A combination of chemotherapy (nedaplatin and 5-fluorouracil) and radiotherapy was initiated. After radiotherapy (20 Gy), CT scans revealed that the swollen lymph node penetrated the gastric wall resulting in a gastro-lymphatic fistula. Although gastrostomy and intestinal fistula repair were performed for gastric decompression and tube feeding, respectively, the patient's general status did not improve and he died two months after interruption of his chemoradiotherapy. The results indicate that there may be some risks of gastro-lymphatic fistula in patients treated with concurrent chemoradiotherapy for advanced esophageal cancer when there are possible signs of involvement by CT scans.
authors.affiliation: Department of Radiology, University of the Ryukyus, Nishihara-cho, Okinawa, Japan.
authors.forename: Goro
authors.initials: G
authors.lastname: Kasuya
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ogawa
authors.forename: Hideaki
authors.initials: H
authors.lastname: Shimoji
authors.forename: Wakana
authors.initials: W
authors.lastname: Tamaki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Karimata
authors.forename: Takafumi
authors.initials: T
authors.lastname: Toita
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Kakinohana
authors.forename: Takuro
authors.initials: T
authors.lastname: Ariga
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nishimaki
authors.forename: Sadayuki
authors.initials: S
authors.lastname: Murayama