Novel finding of high density of activated mast cells in endometrial polyps.
Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.
Al-Jefout
Moamar
M
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Missenden Road, Camperdown, Australia; Muta'h Medical Faculty, Muta'h University, Jordan. Electronic address: drmoamar@yahoo.co.uk.
Black
Kirsten
K
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Missenden Road, Camperdown, Australia.
Schulke
Lauren
L
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Missenden Road, Camperdown, Australia.
Berbic
Marina
M
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia.
Luscombe
Georgina
G
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia.
Tokushige
Natsuko
N
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia.
Manconi
Frank
F
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia.
Markham
Robert
R
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia.
Fraser
Ian S
IS
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Missenden Road, Camperdown, Australia.