Thermus thermophilus strains active in purine nucleoside synthesis.
Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases. High productivity values (t =1 hr) were obtained while completely avoiding adenosine-deaminase degradation of the products. N-2-deoxy-ribosyltransferase activity is described for the first time in hyperthermophilic bacteria.
Almendros
Marcos
M
Biotransformations Group, Servicio de Biotransformaciones Industriales, Parque Científico de Madrid, C/ Santiago Grisolia n masculine 2, 28760 Tres Cantos, Madrid, Spain.
Gago
José-Vicente Sinisterra
JV
Carlos
José Berenguer
JB