title: Serum adipocytokine levels in prostate cancer patients.
abstract: BACKGROUND
  We estimated the circulating levels of adipocytokines such as adiponectin and leptin in nonobese nondiabetic prostate cancer (PCa) patients and compared the results with controls and benign prostate hyperplasia (BPH) patients.
  
  
  METHODS
  Fifty patients with PCa, 20 patients with BPH and 50 healthy volunteers were entered into the study. Their blood samples were investigated for adipocytokines with the ELISA method.
  
  
  RESULTS
  Adiponectin levels were determined as 8.9 and 5.5 microg/ml for the same patients. Leptin concentration was 14.78 ng/ml in organ-confined PCa patients, and 15.24 ng/ml in advanced PCa patients. In control patients, adiponectin and leptin levels were 18.4 and 12.98 ng/ml, respectively.
  
  
  CONCLUSIONS
  Serum adipocytokine levels of PCa patients were significantly different from those of controls and BPH patients who were not obese or diabetic. Therefore, further molecular investigation of these adipocytokines will help understand the mechanism.
authors.affiliation: 1st Urology Clinics, Sişli Etfal Research and Training Hospital, Sisli-Istanbul, Turkey.
authors.forename: Elif Damla
authors.initials: ED
authors.lastname: Arisan
authors.forename: Serdar
authors.initials: S
authors.lastname: Arisan
authors.forename: Gokhan
authors.initials: G
authors.lastname: Atis
authors.forename: Narcin
authors.initials: N
authors.lastname: Palavan-Unsal
authors.forename: Erbil
authors.initials: E
authors.lastname: Ergenekon