Evidence of diversification of dengue virus type 3 genotype III in the South American region.
In order to gain insight into the genetic variability of dengue virus type 3 (DENV-3) genotype III isolated in the Latin American region, phylogenetic analysis were carried out using envelope (E) gene sequences from 57 DENV-3 genotype III strains isolated in 11 Latin American countries. At least six different genotype III clades were observed. Amino acids substitutions were found in domain III E protein neutralization epitopes and in surface-exposed domain II and III E protein amino acid sequences.
de Mora
Domenica
D
Instituto Nacional de Higiene y Medicina Tropical "Leopoldo Inquieta Perez", Julian Coronel y Esmeraldas, Guayaquil, Ecuador.
Andrea
Lucía D'
LD
Alvarez
Macarena
M
Regato
Mary
M
Fajardo
Alvaro
A
Recarey
Ricardo
R
Colina
Rodney
R
Khan
Baldip
B
Cristina
Juan
J