title: An expanded phenotype of maternal SSA/SSB antibody-associated fetal cardiac disease.
abstract: OBJECTIVE
  Conventional manifestations of fetal Sjogren's antibodies (SSA/SSB) associated cardiac disease include atrioventricular block (AVB), transient sinus bradycardia, endocardial fibroelastosis (EFE) and dilated cardiomyopathy. We describe other manifestations of cardiac disease.
  
  
  METHODS
  We describe three fetuses with unique myocardial and conduction system disease.
  
  
  RESULTS
  One had isolated EFE with subsequent mitral and tricuspid valve chordal avulsion, the second had sinoatrial and infrahissian conduction system disease, and in both, neonatal progression to life threatening disease occurred. The third had sinus node dysfunction and atrial flutter.
  
  
  CONCLUSIONS
  These findings expand the clinical phenotype of maternal SSA/SSB antibody associated fetal cardiac disease.
authors.affiliation: The Heart Institute for Children, Hope Children's Hospital, Oak Lawn, IL 60453, USA. cuneo@thic.com
authors.forename: Bettina F
authors.initials: BF
authors.lastname: Cuneo
authors.forename: Janette F
authors.initials: JF
authors.lastname: Strasburger
authors.forename: Alisa
authors.initials: A
authors.lastname: Niksch
authors.forename: Marc
authors.initials: M
authors.lastname: Ovadia
authors.forename: Ronald T
authors.initials: RT
authors.lastname: Wakai