title: Characteristics of the antibodies of two patients who developed daytime hyperglycemia and morning hypoglycemia because of insulin antibodies.
abstract: We encountered two patients who developed daytime hyperglycemia and early morning hypoglycemia because of insulin antibody (IA) that the affinity was extremely lower and the capacity extremely higher than those of IA in the insulin autoimmune syndrome, after their insulin treatment were changed from human insulin to analog insulin.
authors.affiliation: Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Ishizuka
authors.forename: Susumu
authors.initials: S
authors.lastname: Ogawa
authors.forename: Takefumi
authors.initials: T
authors.lastname: Mori
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Nako
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakamichi
authors.forename: Yoshitomo
authors.initials: Y
authors.lastname: Oka
authors.forename: Sadayoshi
authors.initials: S
authors.lastname: Ito