title: [Ocular retention in patients with uveal melanoma managed by a multimodality approach].
abstract: OBJECTIVE
  to analyze ocular survival in eyes with uveal melanoma treated with conservative therapies, in a centre that applies all treatment modalities.
  
  
  METHODS
  Patients diagnosed with uveal melanoma and treated between September 1990 and April 2007 were included in an historical cohorts study.
  
  
  RESULTS
  273 patients were included. 193 were treated with conservative treatments (70.69%) and 80 were enucleated as primary treatment. 14 patients were enucleated after conservative treatment (7.2%). Kaplan-Meier survival analysis showed an 88% survival probability of the eye in the first 5 years after conservative treatment and 83% at 10 years.
  
  
  CONCLUSIONS
  Conservative treatments for uveal melanoma, especially brachitherapy, are safe and effective in relation to tumor control and rate of secondary effects.
authors.affiliation: Unidad de Tumores Intraoculares del Adulto, CSUR del SNS, Servicios de Radioterapia, Oftalmología y Unidad de Investigación, Hospital Clínico Universitario, Valladolid, España. cigore@yahoo.es
authors.forename: C
authors.initials: C
authors.lastname: García-Alvarez
authors.forename: Y
authors.initials: Y
authors.lastname: Muiños
authors.forename: M A
authors.initials: MA
authors.lastname: Saornil
authors.forename: A
authors.initials: A
authors.lastname: Almaraz
authors.forename: F
authors.initials: F
authors.lastname: López-Lara
authors.forename: J M
authors.initials: JM
authors.lastname: Frutos
authors.forename: M F
authors.initials: MF
authors.lastname: Muñoz