title: Spectral domain optical coherence tomographic imaging of geographic atrophy.
abstract: To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using fundus autofluorescence (FAF).
  
  
  
  Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared.
  
  
  
  GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference of 2.7% of the total area.
  
  
  
  SD-OCT can identify and quantitate areas of GA. The size and shape of these areas correlate well to the areas of GA seen on autofluorescence images; however, SD-OCT imaging also provides important cross-sectional anatomic information.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
authors.forename: Brandon J
authors.initials: BJ
authors.lastname: Lujan
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenfeld
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gregori
authors.forename: Fenghua
authors.initials: F
authors.lastname: Wang
authors.forename: Robert W
authors.initials: RW
authors.lastname: Knighton
authors.forename: William J
authors.initials: WJ
authors.lastname: Feuer
authors.forename: Carmen A
authors.initials: CA
authors.lastname: Puliafito