title: Evidence of diversification of dengue virus type 3 genotype III in the South American region.
abstract: In order to gain insight into the genetic variability of dengue virus type 3 (DENV-3) genotype III isolated in the Latin American region, phylogenetic analysis were carried out using envelope (E) gene sequences from 57 DENV-3 genotype III strains isolated in 11 Latin American countries. At least six different genotype III clades were observed. Amino acids substitutions were found in domain III E protein neutralization epitopes and in surface-exposed domain II and III E protein amino acid sequences.
authors.affiliation: Instituto Nacional de Higiene y Medicina Tropical "Leopoldo Inquieta Perez", Julian Coronel y Esmeraldas, Guayaquil, Ecuador.
authors.forename: Domenica
authors.initials: D
authors.lastname: de Mora
authors.forename: Lucía D'
authors.initials: LD
authors.lastname: Andrea
authors.forename: Macarena
authors.initials: M
authors.lastname: Alvarez
authors.forename: Mary
authors.initials: M
authors.lastname: Regato
authors.forename: Alvaro
authors.initials: A
authors.lastname: Fajardo
authors.forename: Ricardo
authors.initials: R
authors.lastname: Recarey
authors.forename: Rodney
authors.initials: R
authors.lastname: Colina
authors.forename: Baldip
authors.initials: B
authors.lastname: Khan
authors.forename: Juan
authors.initials: J
authors.lastname: Cristina