[Rapid resolution of nitrofurantoin-induced interstitial lung disease].
We report the case of a 40-year-old woman diagnosed with interstitial lung disease due to long-term nitrofurantoin therapy. Despite severely distorted bronchiolar architecture and honeycombing confirmed by computed tomography of the thorax, transbronchial biopsy showed a pattern of acute/subacute interstitial pneumonitis and the symptoms and radiographic findings disappeared within 1 month after administration of prednisone. This case shows that nitrofurantoin-induced lung disease may run a benign course and respond favorably to corticosteroids, even when there is radiographic evidence of established lung fibrosis. Transbronchial biopsy might be useful for assessing the reversibility of pulmonary lesions associated with nitrofurantoin.
Viejo
Miguel Angel Núñez
MA
Departamento de Medicina Interna, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, España. manuvi2004@hotmail.com
Fernández Montes
Ana
A
Montes
Javier Velasco
JV
Gómez-Román
José Javier
JJ
Ibarbia
Carmen García
CG
Hernández
José Luis Hernández
JL