Impact of deoxynivalenol on the intestinal microflora of pigs.
Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities.
Waché
Yann J
YJ
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.|French Institute of Agricultural Research (INRA) - UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 - France.
Valat
Charlotte
C
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
Postollec
Gilbert
G
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
Bougeard
Stephanie
S
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
Burel
Christine
C
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.
Oswald
Isabelle P
IP
French Institute of Agricultural Research (INRA) - UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 - France.
Fravalo
Philippe
P
French Agency for Food Safety (AFSSA) - Zoopôle des côtes d'Armor, BP53, 22440 Ploufragan - France.