title: The conserved sporulation protein YneE inhibits DNA replication in Bacillus subtilis.
abstract: Cells of Bacillus subtilis triggered to sporulate under conditions of rapid growth undergo a marked decrease in chromosome copy number, which was partially relieved by a mutation in the sporulation-induced gene yneE. Cells engineered to express yneE during growth were impaired in viability and produced anucleate cells. We conclude that YneE is an inhibitor of DNA replication.
authors.affiliation: Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA.
authors.forename: Lilah
authors.initials: L
authors.lastname: Rahn-Lee
authors.forename: Boris
authors.initials: B
authors.lastname: Gorbatyuk
authors.forename: Ole
authors.initials: O
authors.lastname: Skovgaard
authors.forename: Richard
authors.initials: R
authors.lastname: Losick