title: Human papillomavirus and head and neck cancer: a growing concern.
abstract: Head and neck cancer is increasing in incidence in patients without the usual risk factors for the disease. Practitioners need to be aware that young, non-smoking patients are also at risk for certain types of head and neck cancer. Head and neck cancer in this patient group is likely due to infection of the tonsil and tongue with high-risk strains of human papillomavirus (HPV). There is strong epidemiological and laboratory evidence that HPV is a cause of head and neck cancer. Therefore, any patient with persistent lesions, ulcers, swallowing difficulty, change in voice, or neck mass needs prompt referral to an otolaryngologist- head and neck surgeon.
authors.affiliation: MUSC, 135 Rutledge Ave. MSC 550, Charleston, SC, 29425, USA. gillesmb@musc.edu
authors.forename: M Boyd
authors.initials: MB
authors.lastname: Gillespie
authors.forename: Jake
authors.initials: J
authors.lastname: Smith
authors.forename: Kevin
authors.initials: K
authors.lastname: Gibbs
authors.forename: Theodore
authors.initials: T
authors.lastname: McRackan
authors.forename: Semyon
authors.initials: S
authors.lastname: Rubinchik
authors.forename: Terry A
authors.initials: TA
authors.lastname: Day
authors.forename: Natalie
authors.initials: N
authors.lastname: Sutkowski