Oxylipins from Dracontium loretense.
Four novel oxylipins (1-4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMS(n)) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear (2,3)J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.
Benavides
Angelyne
A
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, SA, Italy.
Napolitano
Assunta
A
Bassarello
Carla
C
Carbone
Virginia
V
Gazzerro
Patrizia
P
Malfitano
Annamaria
A
Saggese
Paola
P
Bifulco
Maurizio
M
Piacente
Sonia
S
Pizza
Cosimo
C