title: Headspace solid phase micro extraction gas chromatographic determination of fenthion in human serum.
abstract: A simple and effective analytical procedure was developed for the determination of fenthion residues in human serum samples. The sample treatment was performed using the headspace solid-phase micro extraction with polyacrylate fiber, which has the advantage to require low amount of serum (1 mL) without tedious pre-treatment. The quantification of fenthion was carried out by gas chromatography-mass spectrometry and the recoveries ranged from 79 to 104% at two spiking levels for 6 replicates. Detection and quantification limits were calculated as 1.51 and 4.54 ng/mL of serum respectively. Two fenthion metabolites fenoxon and fenthion-sulfoxide were also identified.
authors.affiliation: Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.
authors.forename: Konstantinos M
authors.initials: KM
authors.lastname: Kasiotis
authors.affiliation: Pharmacology Department, Medical School, University of Athens, 115 27, Athens, Greece.
authors.forename: Helen
authors.initials: H
authors.lastname: Souki
authors.affiliation: Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.
authors.forename: Angelos N
authors.initials: AN
authors.lastname: Tsakirakis
authors.affiliation: Pharmacology Department, Medical School, University of Athens, 115 27, Athens, Greece.
authors.forename: Haris
authors.initials: H
authors.lastname: Carageorgiou
authors.affiliation: Agroindustrial Robola Growers Cooperative of Kefalllinia, Omala, 28100 Kefallinia, Greece.
authors.forename: Spiridon A
authors.initials: SA
authors.lastname: Theotokatos
authors.affiliation: Chemistry Laboratory, Agricultural University of Athens, Iera Odos 75, 118 55, Athens, Greece.
authors.forename: Serkos A
authors.initials: SA
authors.lastname: Haroutounian
authors.affiliation: Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Kifissia 14561, Athens, Greece.
authors.forename: Kyriaki
authors.initials: K
authors.lastname: Machera