title: Surgical management of moyamoya disease: a review.
abstract: Moyamoya disease (MMD) is a progressive, occlusive disease of the distal internal carotid arteries associated with secondary stenosis of the circle of Willis. Symptoms include ischemic infarcts in children and hemorrhages in adults. Bypass of the stenotic vessel(s) is the primary surgical treatment modality for MMD. Superficial temporal artery-to-middle cerebral artery bypass is the most common direct bypass method. Indirect techniques rely on the approximation of vascularized tissue to the cerebral cortex to promote neoangiogenesis. This tissue may be in the form of muscle, pericranium, dura, or even omentum. This review highlights the surgical options available for the treatment of MMD.
authors.affiliation: Department of Neurological Surgery, College of Medicine, University of South Florida, Tampa, Florida, USA.
authors.forename: Ali A
authors.initials: AA
authors.lastname: Baaj
authors.forename: Siviero
authors.initials: S
authors.lastname: Agazzi
authors.forename: Zafar A
authors.initials: ZA
authors.lastname: Sayed
authors.forename: Maria
authors.initials: M
authors.lastname: Toledo
authors.forename: Robert F
authors.initials: RF
authors.lastname: Spetzler
authors.forename: Harry
authors.initials: H
authors.lastname: van Loveren