[Clinical characteristics of patients with juvenile localized scleroderma].
OBJECTIVE
To investigate the clinical characteristics of juvenile localized scleroderma (JLS).


METHODS
The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.


RESULTS
Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as generalized morphea, and 15 (15%) as a mixed subtype. Nine patients (9%) had family histories of rheumatic or autoimmune diseases, while 16 (16%) might be triggered by unknown factors. Totally 84 patients underwent antinuclear antibody tests and 38 patients (45.2%) had positive results.


CONCLUSIONS
Linear scleroderma are the most frequent subtype of JLS. Localized scleroderma may be associated with some autoimmune-related causes.
Sun
Qiu-Ning
QN
Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Du
Wei
W
Hu
Bin
B
Liu
Pai
P
Yuan
Xie
X