Wacker-type oxidation of alkynes into 1,2-diketones using molecular oxygen.
An intriguing new Wacker-type oxidation of alkynes catalyzed by PdBr(2) and CuBr(2) is described, which opens an efficient access to 1,2-diketones using molecular oxygen. Under the optimized conditions, a variety of alkynes, including diarylalkynes, arylalkylalkynes, and dialkylalkynes, were compatible substrates in this transformation. The mechanism of this reaction was preliminarily investigated by control experiments.
Ren
Wei
W
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China.
Xia
Yuanzhi
Y
Ji
Shun-Jun
SJ
Zhang
Yong
Y
Wan
Xiaobing
X
Zhao
Jing
J