title: De novo malignancy after solid organ transplantation in children.
abstract: The aim of this study was to assess the prevalence of de novo malignancy after solid organ transplantation in childhood. A retrospective questionnaire-based survey was sent to 9 referral centers for pediatric organ transplantation in France. Among 1326 children who underwent solid organ transplantation since 1996, 80 (6%) presented with de novo malignancy posttransplantation during childhood: posttransplant lymphoproliferative disease was the most common (5% of pediatric recipients) comprising 80% of all tumors, with a disproportionately high prevalence among combined liver and small bowel recipients (18%). Various solid tumors were observed mainly among kidney recipients. No skin cancer was reported.
authors.affiliation: Department of Pediatric Hepatology, APHP-Hôpital Bicêtre, Le Kremlin-Bicêtre, France. dominique.debray@bct.aphp.fr
authors.forename: D
authors.initials: D
authors.lastname: Debray
authors.forename: V
authors.initials: V
authors.lastname: Baudouin
authors.forename: F
authors.initials: F
authors.lastname: Lacaille
authors.forename: M
authors.initials: M
authors.lastname: Charbit
authors.forename: C
authors.initials: C
authors.lastname: Rivet
authors.forename: J
authors.initials: J
authors.lastname: Harambat
authors.forename: F
authors.initials: F
authors.lastname: Iserin
authors.forename: S
authors.initials: S
authors.lastname: Di Filippo
authors.forename: C
authors.initials: C
authors.lastname: Guyot