title: Genetics of cardiac repolarization.
abstract: Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.
authors.affiliation: Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA. svati.shah@duke.edu
authors.forename: Svati H
authors.initials: SH
authors.lastname: Shah
authors.forename: Geoffrey S
authors.initials: GS
authors.lastname: Pitt