Primary tracheal tumors: review of 37 cases.
BACKGROUND
Primary tracheal tumors are rare, and composed of various benign and malignant pathologies. Although nationwide epidemiologic studies were reported in western population, study about the oriental population is lacking. The aims of this study were to establish the clinical manifestations and treatment outcomes of primary tracheal tumors and explore the prognostic variables for malignant tracheal tumors.


METHODS
From January 1989 through December 2006, 37 patients (14 with benign tumors, 23 with malignant tumors) were treated in a tertiary referral center. Retrospective review of medical records was performed.


RESULTS
Benign tumors comprised of various pathologies. Except the papilloma cases (n = 3), all of them were managed successfully without recurrence. Squamous cell carcinomas (n = 11) and adenoid cystic carcinomas (n = 9) comprised most of the malignant tumors. Clinical stage was a statistically significant prognostic variable (p = 0.016). Five-year overall survival rate was 41.1% for squamous cell carcinoma and 45.7% for adenoid cystic carcinoma and no statistically significant difference (p = 0.673) was observed.


CONCLUSIONS
Papillomas were difficult to manage, however, other benign tumors were successfully treated. Among malignant tumors, surgery should be considered as the first choice of treatment, regardless of the histologic type, if the tumors are resectable.
Department of Otorhinolaryngology, Seoul National University College of Medicine, Jongno-Gu, Seoul, Korea.
Youngjin
Y
Ahn
Hyun
H
Chang
Yune Sung
YS
Lim
J Hun
JH
Hah
Tack-Kyun
TK
Kwon
Myung-Whun
MW
Sung
Kwang Hyun
KH
Kim
D000293:Adolescent; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009367:Neoplasm Staging; D010212:Papilloma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D014134:Tracheal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D055815:Young Adult