[Late thrombosis in paclitaxel-eluting stent after discontinuation of clopidogrel medication - a case report with 2-year follow-up].
Stent thrombosis after drug eluting stent implantation has been reported to occur a few hours to over dozen months after the procedure and usually within the 4 weeks after discontinuation of antiplatelet medication. We present a case of a very late stent thrombosis which occurred 12 months after paclitaxel eluting stent implantation and four days after clopidogrel discontinuation despide aspirin continuation, and resulted in acute myocardial infarction. The patient was successfully treated with coronary angioplasty and was advised to use clopidogrel indefinitely. This case underlines the possible need for long term antiplatelet medication among patients receiving paclitaxel eluting stents.
Wozakowska-Kapłon
Beata
B
I Kliniczny Oddział Kardiologii, Swietokrzyskie Centrum Kardiologii, 25-736 Kielce. bw.kaplon@poczta.onet.pl
Młodnicki
Maciej
M
Gutkowski
Wojciech
W
D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D000077144:Clopidogrel; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000209:etiology; D003328:Coronary Thrombosis / Q000209:etiology* / Q000628:therapy; D004334:Drug Administration Schedule; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D017239:Paclitaxel