Iridium catalysis for C-H bond arylation of heteroarenes with iodoarenes.
Efficient couplings using equimolar quantities of each coupling partner and multiple C-H bond arylation reactions are achieved with an Ir-based catalytic system for the C-H bond arylation of electron-rich heteroarenes with iodoarenes to construct extended pi-systems. The dramatic ligand effect on reaction efficiency leads to the discovery that Crabtree's catalyst (see scheme) is the optimal catalyst precursor.
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Benoît
B
Department of Chemistry, Graduate School of Science, Nagoya University, and PRESTO Science and Technology Agency, Chikusa, Nagoya 464-8602, Japan.
Yamamoto
Takuya
T
Itami
Kenichiro
K
D001688:Biological Products / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D006860:Hydrogen Bonding; D007455:Iodine / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*
D001688:Biological Products; D007495:Iridium; D002244:Carbon; D007455:Iodine