Left ventricular mechanics in idiopathic dilated cardiomyopathy: systolic-diastolic coupling and torsion.
BACKGROUND
In idiopathic dilated cardiomyopathy (IDC), myocardial deformational parameters and their mutual relationships remain incompletely characterized.


METHODS
Thirty-seven patients with IDC underwent two-dimensional speckle-tracking echocardiography (2D-STE) to assess left ventricular rotation, torsion, and longitudinal, circumferential, and radial systolic and diastolic strains and strain rates. Additionally, 2D-STE was performed in 14 controls.


RESULTS
All deformational parameters on 2D-STE were significantly lower in patients with IDC compared with controls. Seven patients exhibited opposite basal (positive, counterclockwise) and 11 patients exhibited opposite apical (negative, clockwise) rotation at end-systole. Circumferential, radial, and longitudinal early diastolic strain rates were correlated most strongly with the corresponding spatial components of systolic deformation.


CONCLUSIONS
In patients IDC, all torsional, systolic, and diastolic deformational parameters were decreased. Corresponding three-dimensional components of systolic and diastolic deformations were closely coupled. Considerable variation in the direction of basal and apical rotation exists in a subset of patients with IDC.
Meluzin
Jaroslav
J
1st Department of Internal Medicine/Cardioangiology, St Anna Hospital, ICRC, Masaryk University, Brno, Czech Republic. jaroslav.meluzin@fnusa.cz
Spinarova
Lenka
L
Hude
Petr
P
Krejci
Jan
J
Poloczkova
Hana
H
Podrouzkova
Helena
H
Pesl
Martin
M
Orban
Marek
M
Dusek
Ladislav
L
Korinek
Josef
J
D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000000981:diagnostic imaging*; D015150:Echocardiography, Doppler / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014102:Torsion Abnormality / Q000150:complications / Q000000981:diagnostic imaging*; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000000981:diagnostic imaging*