[Primary ciliary dyskinesia. A case report and comparison with 4 previous cases].
We encountered a 59-year-old man, whose chief complaints were sputum and dyspnea on effort. He had suffered from sinusitis since childhood, and chest computed tomography showed bronchiectasis. Electron microscopic examination of bronchial mucosa biopsied by bronchoscopy showed defect of the inner dynein arm in most of his cilia. We diagnosed primary ciliary dyskinesia. Seminal analysis showed no abnormalities, and the etiology of infertility remains unclear. The present case is the fifth case treated at our hospital. In this paper, we compared this case with 4 cases (2 cases of Kartagener's syndrome and 2 cases of primary ciliary dyskinesia without situs invertus) of our hospital, and findings of previous reports. Primary ciliary dyskinesia should be included in the differential diagnosis even in cases of mild bronchiectasis or normal mobility of sperm. Primary ciliary dyskinesia has more variety in radiological and clinical findings than has been recognized.
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center.
Takashi
T
Ishiguro
Noboru
N
Takayanagi
Naoya
N
Hijikata
Yutaka
Y
Yoshii
Koichiro
K
Yoneda
Yousuke
Y
Miyahara
Naho
N
Kagiyama
Ryozo
R
Yano
Daido
D
Tokunaga
Fumiaki
F
Aoki
Hiroo
H
Saito
Mikio
M
Ubukata
Kazuyoshi
K
Kurashima
Tsutomu
T
Yanagisawa
Yutaka
Y
Sugita
Yoshinori
Y
Kawabata
D000328:Adult; D002925:Ciliary Motility Disorders / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged