Tris(pyrazolyl)methane 99mtc tricarbonyl complexes for myocardial imaging.
Novel ether-containing tris(pyrazolyl)methane chelators stabilize thefac-[99mTc(CO)3]+ moiety providing complexes with significant, fast and stable heart uptake, together with a extremely fast liver clearance.
Departamento de Química, Instituto Tecnológico e Nuclear, Estrada Nacional, 10, Sacavém, Portugal.
Leonor
L
Maria
Célia
C
Fernandes
Raquel
R
Garcia
Lurdes
L
Gano
António
A
Paulo
Isabel Cordeiro
IC
Santos
Isabel
I
Santos
D002851:Chromatography, High Pressure Liquid; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds