Clinical practice recommendations for depression.
OBJECTIVE
To provide clinically relevant evidence-based recommendations for the management of depression in adults that are informative, easy to assimilate and facilitate clinical decision making.


METHODS
A comprehensive literature review of over 500 articles was undertaken using electronic database search engines (e.g. MEDLINE, PsychINFO and Cochrane reviews). In addition articles, book chapters and other literature known to the authors were reviewed. The findings were then formulated into a set of recommendations that were developed by a multidisciplinary team of clinicians who routinely deal with mood disorders. The recommendations then underwent consultative review by a broader advisory panel that included experts in the field, clinical staff and patient representatives.


RESULTS
The clinical practice recommendations for depression (Depression CPR) summarize evidence-based treatments and provide a synopsis of recommendations relating to each phase of the illness. They are designed for clinical use and have therefore been presented succinctly in an innovative and engaging manner that is clear and informative.


CONCLUSIONS
These up-to-date recommendations provide an evidence-based framework that incorporates clinical wisdom and consideration of individual factors in the management of depression. Further, the novel style and practical approach should promote uptake and implementation.
Malhi
G S
GS
CADE Clinic, Department of Psychiatry, Royal North Shore Hospital, University of Sydney, NSW, Australia. gmalhi@med.usyd.edu.au
Adams
D
D
Porter
R
R
Wignall
A
A
Lampe
L
L
O'Connor
N
N
Paton
M
M
Newton
L A
LA
Walter
G
G
Taylor
A
A
Berk
M
M
Mulder
R T
RT
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000379:methods; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D011575:Psychoanalytic Therapy / Q000379:methods
D000928:Antidepressive Agents