Mechanism of androgen receptor action.
Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators. We also explore several clinically relevant aspects of the molecular biology of the androgen receptor and its co-regulators.
Gynaecology Research Unit, University Hospitals of Leicester, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom.
Jin
J
Li
Farook
F
Al-Azzawi
D000728:Androgens / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D001842:Bone and Bones / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D015394:Molecular Structure; D018482:Muscle, Skeletal / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000378:metabolism; D011944:Receptors, Androgen / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
D000728:Androgens; D011944:Receptors, Androgen