An efficient aerobic oxidative cyanation of tertiary amines with sodium cyanide using vanadium based systems as catalysts.
The first report on the use of vanadium-based catalysts for oxidative cyanation of tertiary amines with molecular oxygen in the presence of sodium cyanide and acetic acid to afford the corresponding alpha-aminonitriles in good to excellent yields is described.
Singhal
Sweety
S
Process Engineering Applied Chemistry and Biotechnology Division Indian Institute of Petroleum, Dehradun, India.
Jain
Suman L
SL
Sain
Bir
B
D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D012966:Sodium Cyanide / Q000737:chemistry*; D014639:Vanadium / Q000737:chemistry*
D000588:Amines; D014639:Vanadium; D012966:Sodium Cyanide; D010100:Oxygen