Nitazoxanide, tizoxanide and a new analogue [4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide; NTB] inhibit the growth of kinetoplastid parasites (Trypanosoma cruzi and Leishmania mexicana) in vitro.
Manuel Jesús
MJ
Chan-Bacab
Emanuel
E
Hernández-Núñez
Gabriel
G
Navarrete-Vázquez
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology*; D001549:Benzamides / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D007894:Leishmania mexicana / Q000187:drug effects*; D015394:Molecular Structure; D009574:Nitro Compounds; D013844:Thiazoles / Q000494:pharmacology*; D014349:Trypanosoma cruzi / Q000187:drug effects*
D000981:Antiprotozoal Agents; D001549:Benzamides; D009574:Nitro Compounds; D013844:Thiazoles; C104067:tizoxanide; C041747:nitazoxanide