Seizure during hyperbaric oxygen therapy for carbon monoxide toxicity: a case series and five-year experience.
BACKGROUND
Hyperbaric oxygen (HBO) therapy is recommended to reduce the delayed neurologic sequelae resulting from carbon monoxide (CO) toxicity. Although HBO is generally well tolerated, there exists a risk of seizure in all patients that may be increased in patients with predisposing factors including: fever, hypothermia, prior seizure, or brain injury.


METHODS
We present two cases of patients without known risk factors who experienced seizures associated with HBO therapy during treatment for CO toxicity.


CONCLUSIONS
This facility's 5-year experience and a review of the germane literature are also presented to elucidate the risk factors and incidence of seizures in patients treated with HBO for CO toxicity.
Department of Emergency Medicine, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, PA, USA.
Robert W
RW
Sanders
Kenneth D
KD
Katz
Joe
J
Suyama
Jawaid
J
Akhtar
Kevin S
KS
O'Toole
Diann
D
Corll
Regan N
RN
Ladenburger
D000368:Aged; D002249:Carbon Monoxide Poisoning / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012640:Seizures / Q000453:epidemiology / Q000209:etiology*