[Gran versus host disease with oral involvement: report of one case].
Gran versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent local complications which interfere with normal oral functions and facilitate infection spread. We report a 17 years old woman with GVHD associated to lichenoid and ulcerative lesion in the oral mucosa, which responded to the topical administration of a 0.1% tacrolimus ointment.
Facultad de Odontología, Universidad de Chile, Santiago, Chile. grojasalcayaga@yahoo.es
Gonzalo
G
Rojas A
Néstor
N
González G
Cristián
C
Venables G
Daniel
D
Araos H
D000293:Adolescent; D000741:Anemia, Aplastic / Q000601:surgery; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006086:Graft vs Host Disease / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D009059:Mouth Diseases / Q000188:drug therapy / Q000209:etiology*; D009061:Mouth Mucosa; D016559:Tacrolimus / Q000627:therapeutic use
D007166:Immunosuppressive Agents; D016559:Tacrolimus