[The textile materials containing chitosan and proteolytic complex from hepatopancreas of the crab, for the medical purposes].
Positively charged carriers were synthesized on the basis of the cellulose, oxidized cellulose and chitosan; they were used for immobilization of the proteolytic complex from crab hepatopancreas (CHP). Optimum conditions, a method of updating and a degree of updating of the textile carrier for immobilizations at which practically does not occur inactivation the CHP in process immobilizations were found. Under optimal conditions inactivation kinetics during storage of CHP immobilized on the textile carriers was similar to the inactivation kinetics of immobilized pancreatic trypsin. Experiments on rats have shown, that employment of a new material accelerated wound healing process.
Belov
A A
AA
Belova
E N
EN
Filatov
V N
VN
D000818:Animals; D002482:Cellulose / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology; D033364:Decapoda / Q000201:enzymology*; D004800:Enzymes, Immobilized / Q000737:chemistry* / Q000494:pharmacology; D043143:Hepatopancreas / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000737:chemistry* / Q000494:pharmacology; D051381:Rats; D013784:Textiles; D014945:Wound Healing / Q000187:drug effects; D014947:Wounds and Injuries / Q000628:therapy
D004800:Enzymes, Immobilized; D002482:Cellulose; D048271:Chitosan; D010447:Peptide Hydrolases