[Acute coronary syndrome and cocaine].
OBJECTIVE
Cocaine is directly related to the occurrence of acute coronary syndromes (ACS). We analyzed the differential characteristics of consumers who suffer an ACS in our environment.


METHODS
A retrospective study of 914 patients with ACS who entered consecutively to our hospital.


RESULTS
Thirty four patients were consumers (3.7%, CI95%: 2.7-5.2), with an average age of 40.1+/-9.1 years, significantly lower than non-consumers (63.6+/-12.15 years, P<.001). The prevalence increased progressively in younger groups. Most were men (82.4%), with higher consumption of tobacco (88.2% vs. 34.2%, P<.001) and other illegal drugs (35.3% vs 0.9%, P<.001). By contrast, they had less frequently hypertension (26.5 vs. 60.5%, P<.001) or diabetes (11.7 vs. 39.8%, P<.001). There was single vessel disease in 44.1%, and a coronary angiography without significant lesions in 20.6% cases.


CONCLUSIONS
The typical patient with ACS who consumes cocaine is usually a young man, who often takes other drugs and with a lower prevalence of classic risk factors. These data have to be taken into account when considering preventive and therapeutic manoeuvres.
Rodríguez-Esteban
Marcos
M
Hospital Universitario Nuestra Señora de Candelaria, Servicio de Cardiología, Santa Cruz de Tenerife, Tenerife, España. mrodriguez@auna.com
Mesa-Fumero
Javier
J
Facenda-Lorenzo
María
M
Dorta-Macías
Carlos
C
Ramos-López
María
M
Soriano-Vela
Estanislao
E
D054058:Acute Coronary Syndrome / Q000139:chemically induced*; D000328:Adult; D019970:Cocaine-Related Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies