Ligands, cell-based models, and readouts required for Toll-like receptor action.
This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.
Dellacasagrande
Jérôme
J
OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James' Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.com
D000818:Animals; D002460:Cell Line; D005786:Gene Expression Regulation / Q000235:genetics*; D017930:Genes, Reporter / Q000235:genetics; D006801:Humans; D008024:Ligands; D008954:Models, Biological; D010766:Phosphorylation; D021381:Protein Transport; D051193:Toll-Like Receptors / Q000032:analysis* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics
D008024:Ligands; D051193:Toll-Like Receptors