A method to build an analytic model of the 10B(n,alpha)7Li reaction rate space distribution for boron neutron capture therapy (BNCT).
This work provides the basis of a methodology to build a deterministic model for the spatial distribution of the (10)B(n,alpha)(7)Li reaction rate in boron neutron capture therapy (BNCT), as a function of space variables, boron concentration and beam incidence angle in homogeneous isotropic environments but also in different heterogeneous environments. Building the analytic function in a simple homogeneous environment with numerical methods leads to a mathematical formulation of the (10)B(n,alpha)(7)Li reactions rate.
Joint Research Center, PO Box 2 1755 ZG, Petten, The Netherlands. josselin.morand@gmail.com
Josselin
J
Morand
Raymond
R
Moss
Sabet
S
Hachem
Wolfgang
W
Sauerwein
D001881:Borates / Q000627:therapeutic use*; D001895:Boron / Q000627:therapeutic use; D016754:Boron Neutron Capture Therapy / Q000706:statistics & numerical data*; D006801:Humans; D007554:Isotopes / Q000627:therapeutic use; D018020:Lithium Compounds / Q000627:therapeutic use*; D015233:Models, Statistical; D019047:Phantoms, Imaging / Q000706:statistics & numerical data; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data*
D001881:Borates; D007554:Isotopes; D018020:Lithium Compounds; D011838:Radiation-Sensitizing Agents; C021051:lithium borate; D001895:Boron