Ligands, cell-based models, and readouts required for Toll-like receptor action.
This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.
OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James' Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.com
Jérôme
J
Dellacasagrande
D000818:Animals; D002460:Cell Line; D005786:Gene Expression Regulation / Q000235:genetics*; D017930:Genes, Reporter / Q000235:genetics; D006801:Humans; D008024:Ligands; D008954:Models, Biological; D010766:Phosphorylation; D021381:Protein Transport; D051193:Toll-Like Receptors / Q000032:analysis* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics
D008024:Ligands; D051193:Toll-Like Receptors