[Erythropoietin possible influence on the cellular renovation processes of exocervical epithelium in norm, in case of chronic cervicitis and cervical intraepithelial neoplasia 1 and 2].
The blood plasma erythropoietin content, erythropoietin content, erythropoietin and cellular renovation markers expression in exocervical epithelium in reproductive aged women with normal peripheral red blood values were studied. It was determined that erythropoietin expression increased in exocervical epithelium activity (cervical intraepithelial neoplasia 1 and 2), combined with the increase of blood plasma erythropoietin level, activation of pro- and antiapoptosis programs and cellular proliferation processes in cervical epithelium.
M V
MV
Meshcheriakova
Iu M
IuM
Zakharov
E L
EL
Kurenkov
D000293:Adolescent; D000328:Adult; D017209:Apoptosis; D049109:Cell Proliferation; D002584:Cervix Uteri / Q000378:metabolism* / Q000473:pathology; D002908:Chronic Disease; D004848:Epithelium / Q000378:metabolism / Q000473:pathology; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D002575:Uterine Cervicitis / Q000097:blood*; D002578:Uterine Cervical Dysplasia / Q000097:blood* / Q000473:pathology
D004921:Erythropoietin