Azurophilic inclusions in plasma cells.
We report a 45-year-old man with complaints of chest pain and weight loss who was referred for a bone marrow/trephine procedure to the Aga Khan University Hospital. Bone marrow examination showed plasmacytosis of 95% with plasma cells containing coarse Auer rod-like azurophilic inclusions, which failed to stain positively with Sudan Black B or periodic acid Schiff stain. These inclusions have rarely been previously reported as they are more significant morphologically rather than having a prognostic value.
Department of Pathology & Microbiology, Section of Haematology, The Aga Khan University Hospital, PO Box 3500, Stadium Road, Karachi 74800, Pakistan. natasha.ali@aku.edu
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D002637:Chest Pain; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D010950:Plasma Cells / Q000473:pathology*; D011379:Prognosis; D015431:Weight Loss