[Cerebral microdialysis. Options and limits].
Cerebral microdialysis (CMD) is a minimal-invasive monitoring technique for patients with subarachnoidal haemorrhage or severe traumatic brain injury, which allows the investigation of a wide spectrum of compounds in the brain tissue. The aim is a precocious identification of cerebral ischemia and secondary brain damage. The method was introduced in the early 1970s. By using commercial equipment it is nowadays possible to conduct on-line analysis at the bedside in the intensive care unit. The following article discusses the principles of CMD, the most commonly used biomarkers and the options during neurointensive care.
Klinik für Neurochirurgie am Kantonsspital St. Gallen. oliver.gautschi@kssg.ch
Oliver P
OP
Gautschi
Martin
M
Seule
Dieter
D
Cadosch
Marc
M
Land
Jean-Yves
JY
Fournier
Gerhard
G
Hildebrandt
D001921:Brain / Q000378:metabolism*; D001930:Brain Injuries / Q000175:diagnosis* / Q000378:metabolism*; D002545:Brain Ischemia / Q000175:diagnosis* / Q000378:metabolism*; D003422:Critical Care / Q000379:methods*; D006801:Humans; D017551:Microdialysis / Q000295:instrumentation* / Q000379:methods* / Q000639:trends