Unusually high HIV infectiousness in an HIV-, HCV- and HSV-2-coinfected heterosexual man.
We report an HIV-HCV-HSV-2-coinfected man, who infected all of five sequential female sexual partners within seven years. HIV-RNA in semen was unusually high and exceeded that in plasma by one log10. Screening for sexually transmitted diseases remained negative with the exception of HSV-2-seropositivity. Recurrent asymptomatic genital herpes might explain the patient's increased HIV-RNA shedding in semen.
Department of Infectious Diseases, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Andrea
A
Witteck
Sabine
S
Yerly
Pietro
P
Vernazza
D016358:Contact Tracing; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000635:transmission* / Q000821:virology; D019698:Hepatitis C, Chronic / Q000150:complications / Q000635:transmission* / Q000821:virology; D006558:Herpes Genitalis / Q000150:complications / Q000635:transmission* / Q000821:virology; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D012661:Semen / Q000821:virology*; D019562:Viral Load