Image-guided ablation therapy of bone tumors.
A wide range of thermal and cryoablation methods is currently available for the curative eradication or palliative treatment of a variety of bone and soft-tissue tumors. Radiofrequency ablation has been developed as a multipurpose tool for the skeletal system. Cryoablation has the added advantages of direct computed tomography or magnetic resonance visualization and monitoring of treatment outcome with less peri- and postoperative pain. Use of appropriate thermo-sensors and insulation techniques, like carbon dioxide insufflation, results in enhanced safety and efficacy. Ablation of weight-bearing bones has to be supplemented with cement consolidation. The authors present an overview of the current status of percutaneous image-guided ablation therapy of bone and soft-tissue tumors, analyze the merits and limitations of the various systems available, and discuss possible new applications for the future.
Department of Interventional Radiology, Guy's and St. Thomas' Hospital, 1st Floor, Lambeth Wing, Lambeth Palace Road, London SE1 7EH, UK Tarun.Sabharwal@gstt.nhs.uk
Tarun
T
Sabharwal
Konstantinos
K
Katsanos
Xavier
X
Buy
Afshin
A
Gangi
D055011:Ablation Techniques / Q000379:methods*; D001843:Bone Cements / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000601:surgery*; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional; D010166:Palliative Care; D015641:Radiography, Interventional
D001843:Bone Cements