Successful treatment of infective endocarditis in four kidney transplant recipients.
Infective endocarditis (IE) is a serious complication in kidney transplantation, leading to graft loss and a high mortality rate. We report 4 successfully managed cases of IE in kidney transplant recipients. Blood culture revealed Enterococcus in 2 patients, group D Streptococcus in 1, and no bacteria in 1. All of the patients were diagnosed based on at least 2 major Duke criteria for diagnosis of IE. Although a mild increase in the serum creatinine level was observed in 3 out of 4 patients, no graft rejection occurred during the follow-up. Early diagnostic and therapeutic intervention, particularly intensive antibiotic therapy and surgical management can preserve the patient and the kidney allograft. Studies on previous recurrent infections and simultaneous diseases such as cytomegalovirus in these patients are warranted.
Department of Kidney Transplantation, Shaheed Labbafinejad Medical Center, Shaheed Beheshti Medical University, Tehran, Iran. pourrezagholi@unrc.ir
Fatemeh
F
Pour-Reza-Gholi
Farhat
F
Farrokhi
Behzad
B
Einollahi
Eghlim
E
Nemati
D000328:Adult; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D016983:Enterococcus; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D055815:Young Adult