Successful topical hemotherapy with a new occlusive dressing for an intractable ulcer on the toe.
Topical hemotherapy is a method of applying heparinized venous blood directly onto the surface of an ulcer, which is covered with an occlusive hydrocolloidal dressing. It is often effective on chronic ulcers with thick necrosis, because some proteinases and growth factors in plasma are probably involved in the digestion of necrotic tissues and the acceleration of granulation and epithelization. We treated a patient with an intractable ulcer on the toe caused by a peripheral circulatory disturbance due to her systemic sclerosis. As conventional topical hemotherapy cannot be applied to ulcers on the round tip of a toe, we made a device for occlusive dressing of topical hemotherapy which could successfully improve the previously refractory ulcer.
Iwayama-Hibino
Michiko
M
Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan. michikomichikomichiko@hotmail.com
Sugiura
Kazumitsu
K
Muro
Yoshinao
Y
Tomita
Yasushi
Y
D000287:Administration, Topical; D047070:Bandages, Hydrocolloid; D001691:Biological Therapy / Q000379:methods*; D001769:Blood; D005260:Female; D016523:Foot Ulcer / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D006493:Heparin; D006801:Humans; D008875:Middle Aged; D009779:Occlusive Dressings; D045743:Scleroderma, Diffuse / Q000150:complications; D014034:Toes
D006493:Heparin