Expression of interleukin-5 and tumor necrosis factor alpha in cervical carcinoma.
Interleukin-5 (IL-5) levels were significantly higher in vaginal washing fluids from patients with cervical carcinoma than in those from patients with carcinoma in situ and controls. Tumor necrosis factor alpha levels did not differ among the three groups. Detection of IL-5 in cervical secretions may be a useful marker for evaluating aggressive local immune response in cervical carcinoma.
Lee
Dae Woo
DW
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seodaemun-gu, Seoul, South Korea.
Kim
Young Tae
YT
Kim
Sang Wun
SW
Kim
SungHoon
S
Kim
Jae Hoon
JH
Kang
Myung Hwa
MH
Hwang
Jeong Hye
JH
Lim
Jong baeck
Jb
D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D006801:Humans; D015848:Interleukin-5 / Q000096:biosynthesis*; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis*; D002583:Uterine Cervical Neoplasms / Q000276:immunology*; D014621:Vagina / Q000276:immunology
D014408:Biomarkers, Tumor; D015848:Interleukin-5; D014409:Tumor Necrosis Factor-alpha