Planning a serial dilution test with multiple dilutions.
The dilutions used in a serial dilution test determine which concentrations it can estimate well. Two criteria help to select how many and which dilutions to use. The first criterion is a low probability of outcomes with either all growth or all non-growth tubes at the concentrations of interest. The second criterion considers how far the estimated concentration (MPN) is likely to be from the actual concentration.
Blodgett
Robert J
RJ
Food and Drug Administration, Center for Applied Nutrition and Food Safety, 5100 Paint Branch Parkway, College Park, MD 20740, USA. robert.blodgett@fda.hhs.gov
D001419:Bacteria / Q000254:growth & development*; D015169:Colony Count, Microbial / Q000379:methods*; D003470:Culture Media / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D011336:Probability; D012692:Serial Passage
D003470:Culture Media