Microbial conversion of L-ascorbic acid to L-erythroascorbic acid.
We found that a strain of Penicillium sp. effectively converted L-ascorbic acid to a five-carbon analog, which was identified as L-erythroascorbic acid based on spectroscopic analysis. The conversion was achieved by growing culture or washed mycelia, with a yield of approximately 20-30% (mol/mol). The processes for the bioconversion and purification of the product are described.
Kyotani
Daiki
D
Department of Applied Biological Science, Tokyo University of Agriculture and Technology, 3-5-8 Saiwaicho, Fuchu, Tokyo 183-8509, Japan.
Hasegawa
Keiko
K
Ohishi
Hideo
H
Wu
Wenhui
W
Wang
Liyun
L
Hasumi
Keiji
K
D001205:Ascorbic Acid / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D008969:Molecular Sequence Data; D010407:Penicillium / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism*; D012988:Soil Microbiology
C005056:isoascorbic acid; D001205:Ascorbic Acid