Clinical consensus conference: survey on Gram-positive bloodstream infections with a focus on Staphylococcus aureus.
The increased incidence over the past decade of bloodstream infections (BSIs) caused by gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus, highlights the critical need for a consistent approach to therapy. However, there is currently no international consensus on the diagnosis and management of gram-positive BSIs. The Clinical Consensus Conference on Gram-Positive Bloodstream Infections was convened as a session at the 9th International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections held in 2007. Participants discussed various aspects of the practical treatment of patients who present with gram-positive BSI, including therapeutic options for patients with BSIs of undefined origin, the selection of appropriate empirical therapy, and treatment of complicated and uncomplicated BSIs. The opinions of participants about these key issues are reflected in this article.
Department of Cardiology, West-German Heart Center, Essen, Germany. cknaber@web.de
Christoph K
CK
Naber
Larry M
LM
Baddour
Evangelos J
EJ
Giamarellos-Bourboulis
Ian M
IM
Gould
Mathias
M
Herrmann
Bruno
B
Hoen
Adolf W
AW
Karchmer
Yoshio
Y
Kobayashi
Roman S
RS
Kozlov
Daniel
D
Lew
José M
JM
Miró
Robert C
RC
Moellering
Philippe
P
Moreillon
Georg
G
Peters
Ethan
E
Rubinstein
Harald
H
Seifert
G Ralph
GR
Corey
D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D011795:Surveys and Questionnaires