Polystyrene-bound Mn(T4PyP): a highly efficient and reusable catalyst for biomimetic oxidative decarboxylation of carboxylic acids with sodium periodate.
In this report, highly efficient oxidative decarboxylation of carboxylic acids with sodium periodate catalyzed by a supported manganese(III) porphyrin is described. In the presence of manganese(III) tetra(4-pyridyl)porphyrin supported on cross-linked chloromethylated polystyrene, [Mn(T4PyP)-CMP], as catalyst, carboxylic acids were converted to their corresponding carbonyl compounds via oxidative decarboxylation with sodium periodate using imidazole as axial ligand. The oxidation of anti-inflammatory drugs such Indomethacin and Ibuprofen was carried out successfully and the decarboxylated products were obtained. This catalyst can be reused several times without loss of its catalytic activity in the oxidation reactions.
Moghadam
Majid
M
Department of Chemistry, Catalysis Division, University of Isfahan, Isfahan, Iran. moghadamm@sci.ui.ac.ir
Tangestaninejad
Shahram
S
Mirkhani
Valiollah
V
Mohammadpoor-Baltork
Iraj
I
Sirjanian
Narges
N
Parand
Somayeh
S
D040761:Biomimetic Materials / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D003653:Decarboxylation; D008345:Manganese / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry*; D010084:Oxidation-Reduction; D010504:Periodic Acid / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry*
C540152:5,10,15,20-tetra(4-pyridyl)porphyrin; D002264:Carboxylic Acids; D008665:Metalloporphyrins; D011137:Polystyrenes; D011166:Porphyrins; D010504:Periodic Acid; D008345:Manganese; C009288:metaperiodate