Ganglioside GM3 and its biological functions.
Metabolism, topology, and possible mechanisms for regulation of the ganglioside GM3 content in the cell are reviewed. Under consideration are biological functions of GM3, such as involvement in cell differentiation, proliferation, oncogenesis, and apoptosis.
Prokazova
N V
NV
Institute of Experimental Cardiology, Russian Cardiology Research Center, Russian Ministry of Health, 121552 Moscow, Russia. prokazova@cardio.ru
Samovilova
N N
NN
Gracheva
E V
EV
Golovanova
N K
NK
D000818:Animals; D002240:Carbohydrate Sequence; D002453:Cell Cycle / Q000502:physiology; D049109:Cell Proliferation; D005679:G(M3) Ganglioside / Q000096:biosynthesis* / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D008969:Molecular Sequence Data; D015394:Molecular Structure; D018919:Neovascularization, Physiologic / Q000502:physiology
D005679:G(M3) Ganglioside