Monitoring the formation of coordination complexes using electrospray mass spectrometry.
cis,trans-1,3,5-Triaminocyclohexane (trans-tach) has been shown to be an excellent ligand in the synthesis of discrete complexes, molecular clusters, and infinite architectures. Herein, we report the Schiff-base derivitization of trans-tach to form cis,trans-1,3,5-tris (pyridine-2-carboxaldimino) cyclohexane (ttop), and the complexation of this ligand with copper(II) salts. The complexation reaction leads to the crystallization of transition-metal complexes with nuclearities of 1, 2, and 4, and the formation of the complexes can be followed stepwise, in real time, using electrospray mass spectrometry.
WestCHEM, Department of Chemistry, The University of Glasgow, Glasgow G12 8QQ, UK.
Jennifer S
JS
Mathieson
Geoffrey J T
GJ
Cooper
Alexandra L
AL
Pickering
Marco
M
Keller
De-Liang
DL
Long
Graham N
GN
Newton
Leroy
L
Cronin