Clinical manifestations and diagnosis of lyme borreliosis.
Lyme borrelosis is a multi-systemic disease caused byBorrelia burgdorferisensu lato. A complete presentation of the disease is an extremely unusual oberservation, in which a skin lesion follows a tick bite, the lesion itself is followed by heart and nervous system involvement, and later on by arthritis; late involvement of the eye, nervous system, joints and skin may also occur. Information on the relative frequency of individual clinical manifestations of Lyme borreliosis is limited; however, the skin is most frequently involved and skin manifestations frequently represent clues for the diagnosis. The only sign that enables a reliable clinical diagnoisis of Lyme borreliosis is a typical erythema migrans. Laboratory confirmation of a borrelial infection is needed for all manifestations of Lyme borreliosis, with the exception of typical skin lesions.
Franc
F
Strle
Gerold
G
Stanek
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001168:Arthritis / Q000382:microbiology / Q000473:pathology; D005128:Eye Diseases / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008193:Lyme Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D009205:Myocarditis / Q000382:microbiology / Q000473:pathology; D012867:Skin / Q000473:pathology; D017192:Skin Diseases, Bacterial / Q000382:microbiology / Q000473:pathology
D000900:Anti-Bacterial Agents