[Acceptance and safety of vaccines].
As a result of decreasing willingness to be vaccinated some diseases, which seemingly had been eradicated, may reappear. One example for this is the increase of measles cases in the United Kingdom since the 1990s after a decrease of immunization rate in response to a subsequently discredited publication suggesting a link between the triple measles, mumps and rubella vaccine and autism. As the incidence of vaccine preventable diseases decreases, vaccine safety dominates personal risk-benefit analysis. To deal with such concerns this review discusses pre- and post-licensing procedures controlling vaccine safety, taking HPV vaccination as well as vaccination against rotavirus as examples.
Sanofi Pasteur MSD GmbH, Leimen.
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Bartz
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von Knebel-Döberitz
D001294:Attitude to Health; D006801:Humans; D008457:Measles / Q000276:immunology; D008458:Measles Vaccine; D009107:Mumps / Q000276:immunology; D009108:Mumps Vaccine; D010342:Patient Acceptance of Health Care; D012400:Rotavirus Infections / Q000276:immunology; D022243:Rotavirus Vaccines / Q000627:therapeutic use; D012409:Rubella / Q000276:immunology; D012411:Rubella Vaccine; D012449:Safety / Q000592:standards; D012941:Social Responsibility; D014612:Vaccines / Q000592:standards* / Q000627:therapeutic use*
D008458:Measles Vaccine; D009108:Mumps Vaccine; D022243:Rotavirus Vaccines; D012411:Rubella Vaccine; D014612:Vaccines