Successful management of membranoproliferative glomerulonephritis type I in pregnancy.
OBJECTIVE
We report the successful management of a pregnancy with preexisting nephrotic syndrome due to biopsy-proven primary membranoproliferative glomerulonephritis type I.


METHODS
A 21-year-old Turkish woman with membranoproliferative glomerulonephritis type I was followed up by the obstetrics and gynecology, and nephrology departments of a university hospital throughout her pregnancy starting from the 25th week of gestation.


RESULTS
Due to progression of intrauterine growth retardation and fetal distress, a cesarean section was performed in the 33rd week of gestation. Although creatinine was unchanged, proteinuria increased with relatively stable albumin levels 3 months after delivery and her treatment was adjusted accordingly.


CONCLUSIONS
If the mother is not suffering from hypertension or renal insufficiency, specific therapy for membranoproliferative glomerulonephritis type I during pregnancy provided by a nephrologist together with regular obstetric care may allow the patient to have a viable fetus, which might be growth retarded if proteinuria is increased.
Department of Obstetrics and Gynecology, Yuzuncu Yil University School of Medicine, Van, Turkey. mkurdoglu@yyu.edu.tr
Mertihan
M
Kurdoglu
Zehra
Z
Kurdoglu
Ertan
E
Adali
Yasemin
Y
Soyoral
Reha
R
Erkoc
D005260:Female; D015432:Glomerulonephritis, Membranoproliferative; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011248:Pregnancy Complications; D055815:Young Adult