[Primary malignant tumor of the appendix: clinicopathological analysis of 22 cases].
To investigate the clinicopathological and immunohistochemical features of primary malignant tumor of the appendix.



The clinical data were reviewed; and histopathological and immunohistochemical features were analyzed in 22 cases with primary malignant tumor of the appendix.



In 22 cases of primary malignant tumor of the appendix, 19 cases were carcinoid and 3 were adenocarcinoma. Immunohistochemistry showed that the carcinoid was positively reacted to the neuroendocrine markers, and the adenocarcinoma was negatively reacted to the neuroendocrine markers.



Immunohistochemistry is useful in diagnosis of primary malignant tumor of the appendix, a rare type of cancer.
Huang
Bin
B
Department of Pathology, The First Peopleos Hospital of Xiaoshan, Hangzhou, Xiaoshan 311200, China.
Di
Mei-juan
MJ
Liu
Hong-sheng
HS
Qiu
Ling-ling
LL
Sun
Li-jun
LJ
Xu
Jin-ping
JP
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D001063:Appendiceal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D055815:Young Adult