Genetic diversity of porcine circovirus type 2 in Korean pigs with postweaning multisystemic wasting syndrome during 2005-2007.
The comparison of nucleotide and deduced amino acid sequence was conducted with 9 porcine circovirus type 2 (PCV2) strains isolated from PCV2-infected pigs with postweaning multisystemic wasting syndrome (PMWS) and 50 tissue samples obtained from PCV2-infected 50 pigs with PMWS during 2005-2007. At amino acid positions 88-89 of the ORF2 gene, 50 Korean PCV2 had amino acids PR/L consistent with group 1 PCV2, whereas 9 Korean PCV2 contained amino acids KI, characteristic of group 2 PCV2. Phylogenetically, 47, 3, 2 and 7 Korean PCV2 belonged to subgroups 1A/B (79.7%), 1C (5.1%), 2D (3.4%) and 2E (11.9%), respectively. Although the predominant Korean PCV2 was subgroup 1A/B, subgroups 1C and 2E were still circulating and subgroup 2D PCV2 were found to be newly emerged in Korea.
Kim
Ha-Hyun
HH
Bio-Therapy Human Resources Center, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Park
Sang-Ik
SI
Hyun
Bang-Hun
BH
Park
Su-Jin
SJ
Jeong
Young-Ju
YJ
Shin
Dong-Jun
DJ
Chun
Young-Hyun
YH
Hosmillo
Myra
M
Lee
Bong-Joo
BJ
Kang
Mun-Il
MI
Cho
Kyoung-Oh
KO
D000818:Animals; D017925:Circovirus / Q000145:classification* / Q000235:genetics*; D014644:Genetic Variation; D007723:Korea / Q000453:epidemiology; D010802:Phylogeny; D053570:Porcine Postweaning Multisystemic Wasting Syndrome / Q000453:epidemiology / Q000821:virology*; D012189:Retrospective Studies