The role of imaging in chronic degenerative mitral regurgitation.
Chronic degenerative mitral regurgitation (MR) is a complex problem, which requires an integrated assessment of etiology, pathophysiology, and severity to enable informed clinical decision-making. A multidisciplinary approach is required, with input from the clinician, imager, and surgeon. This review begins with a discussion of essential echocardiographic and surgical mitral valve (MV) anatomy, which dictates suitability for repair when indicated. The echocardiographic and Doppler principles, which underlie the quantitation of MR severity, are summarized in the next section, followed by a critical examination of left ventricular systolic function in this disorder. A brief discussion of the important role of imaging in the developing field of percutaneous MV repair is included. The methodical and objective noninvasive assessment of degenerative MR herein reviewed is intended to help guide management decisions for patients with this challenging valve lesion.
Brigham And Women's Hospital, Boston, Massachusetts, USA.
Patrick
P
O'Gara
Lissa
L
Sugeng
Roberto
R
Lang
Maurice
M
Sarano
Judy
J
Hung
Subha
S
Raman
Gregory
G
Fischer
Blasé
B
Carabello
David
D
Adams
Mani
M
Vannan
D006328:Cardiac Catheterization; D006348:Cardiac Surgical Procedures; D002908:Chronic Disease; D003299:Cooperative Behavior; D003952:Diagnostic Imaging / Q000379:methods; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D006801:Humans; D008943:Mitral Valve / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D010348:Patient Care Team; D018579:Patient Selection; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016277:Ventricular Function, Left