[Role of cardiac resynchronization therapy for treatment of heart failure].
Cardiac resynchronization therapy by a biventricular pacemaker or defibrillator is recommended for treating selected patients with systolic heart failure who are in NYHA class III or IV despite optimal medical therapy, have a left ventricular ejection fraction of < or = 35%, and a QRS width of > or = 120 ms. Improvement in symptoms or ventricular remodelling is observed in 50-80% of patients. In order to improve response to treatment, several strategies are proposed, including patient selection, lead positioning and device optimization.
Service de médecine interne, HUG, 1211 Genève 14.
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Berney Lamielle
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Burri
D002304:Cardiac Pacing, Artificial; D006333:Heart Failure / Q000628:therapy*; D006801:Humans