[Segmental Darier disease : treatment with pulsed dye laser].
Darier disease is often associated with pruritus and an unpleasant odor, causing medical and emotional problems. Ablative laser therapy has proven effective in ameliorating these symptoms. Side effects of this approach include permanent hypopigmentation and a risk of scarring. We present two cases where non-ablative therapy with pulsed dye lasers proved a safe and effective way to manage the intertriginous lesions. Although the mechanism of action is unclear, our success indicates that pulsed dye laser therapy is an option in Darier disease. Larger numbers of patients, ideally in multicenter studies, must be treated in this way to confirm our results.
Laserklinik Karlsruhe, Kaiserstrasse 104, 76133, Karlsruhe, Deutschland.
L
L
Schmitt
S
S
Roos
C
C
Raulin
S
S
Karsai
D000328:Adult; D007644:Darier Disease / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D054025:Lasers, Dye / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019233:Retreatment