Angina: Ivabradine for treatment of stable angina pectoris.
The ASSOCIATE study investigators have reported that the I(f) current inhibitor, ivabradine, is safe, improves exercise performance, and delays the development of ischemia in patients with chronic stable angina beingtreated with atenolol. ivabradine should be considered in the medical management of symptom-limited patients with angina, when heart rate is suboptimally controlled.
de Silva
Ranil
R
Fox
Kim M
KM
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001262:Atenolol / Q000627:therapeutic use; D001552:Benzazepines / Q000627:therapeutic use*; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D017079:Exercise Tolerance / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D000077550:Ivabradine; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000889:Anti-Arrhythmia Agents; D001552:Benzazepines; D000077550:Ivabradine; D001262:Atenolol