A case of fulminant type 1 diabetes with coxsackie B4 virus infection diagnosed by elevated serum levels of neutralizing antibody.
A 39-year-old woman with hyperglycemia and ketonuria but with normal HbA1c level was diagnosed as having fulminant type 1 diabetes. The patient had 8-fold increase in the plasma titer of coxsackie B4 virus neutralizing antibody. Infection with coxsackie B4 virus was associated with fulminant type 1 diabetes.
Department of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Hajime
H
Akatsuka
Yutaka
Y
Yano
Esteban C
EC
Gabazza
John
J
Morser
Ryoma
R
Sasaki
Toshinari
T
Suzuki
Ryoko
R
Fujiwara
Akira
A
Katsuki
Yoshiyuki
Y
Takei
Yasuhiro
Y
Sumida
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D029822:Enterovirus B, Human; D004769:Enterovirus Infections / Q000175:diagnosis*; D005260:Female; D005334:Fever / Q000821:virology; D006442:Glycated Hemoglobin / Q000378:metabolism; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D009500:Neutralization Tests; D011141:Polyuria / Q000821:virology
D001323:Autoantibodies; D006442:Glycated Hemoglobin; D007074:Immunoglobulin G