[Use of precultivative multipotent mesenchymal stromal cells isolated from autologic bone marrow in treatment of non-healing autoimmune gastric ulcers].
It is shown that multipotent mesenchymal stromal cells (MMSC) grafted to the zone of ulcer defect contribute to better wound repair in case of chronic non-healing gastric ulcers. It is noted that precultivative MMSC isolated from bone marrow achieve their bioregulatory activity in patient's organism not at once but due to prolonged functioning in the grafting zone (not less than 30 days).
Askarov
M B
MB
Shumakov
V I
VI
Onishchenko
N A
NA
Krasheninnikov
M E
ME
D000818:Animals; D015551:Autoimmunity; D001854:Bone Marrow Cells; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D004195:Disease Models, Animal; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation; D039902:Multipotent Stem Cells / Q000637:transplantation*; D051381:Rats; D013276:Stomach Ulcer / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D013997:Time Factors; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014945:Wound Healing