Compliance with and response to hepatitis B vaccination in remaining quilombo communities in Central Brazil.
Compliance with and responses to the hepatitis B vaccine were evaluated in remaining quilombo communities in Central Brazil. A total of 708 individuals who were susceptible to hepatitis B virus infection were invited to participate in the hepatitis B vaccination program in eight communities. Although 567 (80%) individuals received the first dose, only 198 (28%) complied with the full vaccination scheme. Of 148 subjects who agreed to be tested for anti-HBs, 123 (83.1%; 95%CI: 75.9-88.6) responded to the vaccine. A geometric mean titer of 512mIU/mL (95%CI: 342.5-765.3) was found. Male sex and older age were independently associated with non-response. Additional health education programs and alternative hepatitis B vaccine schedules are needed to improve the vaccination coverage in these communities in Central Brazil.
Departamento de Farmácia-Bioquímica, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brasil.
Ana Rita C
AR
Motta-Castro
Selma A
SA
Gomes
Clara F T
CF
Yoshida
Juliana C
JC
Miguel
Sheila A
SA
Teles
Regina M B
RM
Martins
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044383:Black People / Q000706:statistics & numerical data*; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood*; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D055815:Young Adult
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines