[The influence of hydrogene ion concentrations on peritoneal macrophage plasma membrane's photosensitivity].
It was demonstrated on macrophages treated with UV irradiation dose 9 J/sm2 (lamda max =306 nm) that intra- or extracellular pH reducing lead to decrease the number of cells with damaged membranes in macrophage population. An intra- or extracellular pH elevation leads to increase of UV-irradiation membrane-acting effect. It was also shown that pH-dependence of UV-irradiation damage effect has been lost after preliminary osmotic swelling of cells. The cells survived after UV-irradiation in doses 8 and 10 J/sm2 (lamda max =297 nm) have an intracellular pH lower than non-irradiated cells.
Pirutin
S K
SK
Turovetskiĭ
V B
VB
Kudriashov
Iu B
IuB
D000818:Animals; D002462:Cell Membrane / Q000502:physiology / Q000528:radiation effects*; D006863:Hydrogen-Ion Concentration; D017737:Macrophages, Peritoneal / Q000502:physiology / Q000528:radiation effects*; D051379:Mice; D011836:Radiation Tolerance; D014466:Ultraviolet Rays