Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature.
The study includes a case report and a literature review. The main objective of this study is to present a case of spondylodiscitis due to a fungal pathogen, Blastoschizomyces capitatus and to review the published literature on this emergent fungus in etiology of spondylodiscitis, and osteomyelitis. Osteoarticular involvement due to B. capitatus has been reported in six cases, and vertebral involvement has been seen in five of them. All of these cases had underlying malignancy. Infection is usually advanced at presentation. Case notes and online databases were reviewed. Organism was isolated from bone material in all of the cases and antibiotic treatment by antifungal agents cured the infection. We present another case of infectious spondylodiscitis due to B. capitaus, which is reported first in Turkey and tried to attract attendance to this emergent fungal pathogen as an etiologic agent of spine infections in cancer patients.
Trakya University School of Medicine, Edirne, Turkey. adogancelik@yahoo.com.tr
Aygul Dogan
AD
Celik
Resat
R
Ozaras
Serda
S
Kantarcioglu
Ali
A
Mert
Fehmi
F
Tabak
Recep
R
Ozturk
D000368:Aged; D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D055157:Dipodascus / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*; D015299:Discitis / Q000382:microbiology*; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D007654:Ketoconazole / Q000494:pharmacology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D008826:Microbial Sensitivity Tests; D009281:Naphthalenes / Q000494:pharmacology; D009894:Opportunistic Infections / Q000188:drug therapy; D011859:Radiography; D000077291:Terbinafine; D016896:Treatment Outcome
D000935:Antifungal Agents; D009281:Naphthalenes; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole; D000077291:Terbinafine; D007654:Ketoconazole