Tissue proteomics: a new investigative tool for renal biopsy analysis.
Renal biopsy is viewed as the gold standard for diagnosis and management of many kidney diseases, especially glomerulopathies. However, the histopathological descriptions currently used in clinical practice often are neither diagnostic nor prognostic. The paper by Sethi et al. highlights the availability of a newer investigative tool that can be used to better define pathogenesis and, perhaps more important, to discover robust biomarkers of kidney disease cause and outcome.
Sedor
John R
JR
Department of Medicine, Case Western Reserve University School of Medicine and the CWRU Center for the Study of Kidney Biology and Disease, Cleveland, Ohio, USA. jrs4@case.e
D001706:Biopsy / Q000379:methods; D006801:Humans; D007668:Kidney / Q000737:chemistry; D007674:Kidney Diseases / Q000473:pathology*; D013058:Mass Spectrometry; D042282:Microdissection; D011506:Proteins / Q000032:analysis / Q000302:isolation & purification; D040901:Proteomics / Q000379:methods*
D011506:Proteins