[Randomized clinical trial between nutritional counselling and commercial hypocaloric diet in weight loss in obese patients with chronic arthropathy].
OBJECTIVE
The aim of our work was to evaluate in obese patients with an indication of replacement surgery for degenerative osteoarthritis, the utility of a hypocaloric diet with Optisource vs nutritional counseling.


METHODS
Thirty six patients were randomized in both branches: diet I with lunch and dinner substituted by two Optisource (1109,3 kcal/day, 166,4g of carbohydrates (60%), 63g of proteins (23%), 21,3g of lipids 17%) and diet II with nutritional counselling with a decrease of 500 cal/day from the previous dietary intake. Before and 3 months after treatment, a nutritional and biochemical study was performed.


RESULTS
Nineteen patients were randomized in group I and 17 patients in group II. 19 patients finished the study in group I and 14 in group II. Weight loss was higher in group I than II (7,7 [4,7] vs 3,92 [3,32] kg; P=.05), with a significant decrease of HOMA and diastolic blood pressure in group I. Decreases of body mass index (-2,9 [1,8] vs -1,4 [0,9]; P=.05), fat mass (-3,8 [3,4] vs -2,3 [1,7] kg; P=.0,05) and HOMA (-2,0 [2,2] vs -0,4 [1,82]; P=.05) were higher in group I than II.


CONCLUSIONS
Obese patients with chronic osteoarthritis treated with a mixed diet supplemented with a commercial hypocaloric formula improved weight, fat mass and HOMA in a better way than patients treated with a dietary counselling alone.
Instituto de Endocrinología y Nutrición, Facultad de Medicina y Unidad de Apoyo a la Investigación, Valladolid, España. dadluis@yahoo.es
Daniel A
DA
De Luis
Olatz
O
Izaola
Manuel
M
García Alonso
Manuel
M
González Sagrado
Rosa
R
Conde
Rocío
R
Aller
Gloria
G
Cabezas
Soledad
S
Rojo
D031204:Caloric Restriction; D002908:Chronic Disease; D037001:Directive Counseling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D044623:Nutrition Therapy; D009765:Obesity / Q000150:complications* / Q000178:diet therapy*; D010003:Osteoarthritis / Q000150:complications*; D015431:Weight Loss