[Analysis of the effectiveness of beta-blockers for intraocular pressure and visual field in primary open-angle glaucoma].
OBJECTIVE
The aim of this study was the evaluation of beta-blockers efficiency (as a monotherapy) in the lowering of IOP and the evolution of the visual field.


METHODS
An observational clinical study was carried out over a determined period of time (January 2005-January 2007) on a number of 73 eyes with primary open-angle glaucoma in which one parameter was observed: IOP; on a number of 77 eyes with primary open-angle glaucoma the evolution of the visual field, while receiving specific treatment, was observed.


RESULTS
Pressure release situated at 21.65%, with initial medium IOP at 23.95, and a final value of 17.51; p <0.0001. The aspect of the visual field suffered no negative transformations and no improvements either. The MD and PD parameters were recorded. CONCLUSIONS Beta-blockers can be efficient in monotherapy by offering the reduction and stabilisation of IOP. No problems with regard to tolerability in the eyes observed; no negative side effects emerged because it was not administered to patients which suffered from heart diseases or bronchial asthma. However, patient satisfaction is reduced by an administration of twice a day.
Dobre
Xenia
X
Spitalul De Urgenta Sf. Apostol Andrei Galati.
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D015784:Betaxolol / Q000008:administration & dosage*; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D012189:Retrospective Studies; D013999:Timolol / Q000008:administration & dosage*; D014065:Tonometry, Ocular / Q000379:methods; D016896:Treatment Outcome; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields / Q000187:drug effects*
D000319:Adrenergic beta-Antagonists; D013999:Timolol; D015784:Betaxolol