A new chalcone from Pongamia pinnata and its antioxidant properties.
The root bark of Pongamia pinnata Pierre [syn P. glabra (family: Fabaceae)] afforded a new chalcone (karanjapin) and two known flavonoids, a pyranoflavonoid (karanjachromene) and a furanoflavonoid (karanjin) The structure of karanjapin has been established from extensive 2D NMR spectral studies as beta,2'-dihydroxy-a,4'-dimethoxy-3,4-methylenedioxychalcone. Karanjapin and karanjachromene were found to possess significant antioxidant activity. This may play an important role in the pathogenesis of several diseases.
Centre of Advanced Studies on Natural Products including Organic Synthesis, Department of Chemistry, Calcutta University, 92 A.P.C. Road, Kolkata-700 009, India.
Anindita
A
Ghosh
Suvra
S
Mandal
Avijit
A
Banerji
Manoj
M
Kar
Julie
J
Banerji
D000975:Antioxidants / Q000737:chemistry*; D047188:Chalcones / Q000737:chemistry*; D033641:Millettia / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry
D000975:Antioxidants; D047188:Chalcones; C541193:karanjapin