Human Th17 cells in infection and autoimmunity.
IL-17-producing T cells (Th17) have been identified in mice as a distinct lineage of CD4(+) T helper cells. Since their discovery, efforts have been made in characterizing human Th17 cells and the factors involved in their differentiation and in understanding the role these cells play in protective immunity and autoimmune diseases.
Sallusto
Federica
F
Institute for Research in Biomedicine, Bellinzona, Switzerland. federica.sallusto@irb.unisi.ch
Lanzavecchia
Antonio
A
D015551:Autoimmunity; D006801:Humans; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*