Alkanes to carboxylic acids in aqueous medium: metal-free and metal-promoted highly efficient and mild conversions.
A convenient and clean route to transform, in aqueous medium, various alkanes to carboxylic acids via single-pot carboxylation with CO and water, under mild conditions, has been achieved, proceeding efficiently and selectively even without any metal catalyst and any acid additive, at low temperatures; the relevant hydroxylating role of H(2)O and radical mechanisms are disclosed by radical-trap, H(2)(18)O and DFT studies.
Centro de Química Estrutural, Complexo I, Instituto Superior Técnico, TU Lisbon, Av. Rovisco Pais, 1049-001, Lisbon, Portugal.
Marina V
MV
Kirillova
Alexander M
AM
Kirillov
Maxim L
ML
Kuznetsov
José A L
JA
Silva
João J R
JJ
Fraústo da Silva
Armando J L
AJ
Pombeiro