The role of phenoxymethylpenicillin, amoxicillin, metronidazole and clindamycin in the management of acute dentoalveolar abscesses--a review.
Antibiotics are the most widely prescribed category of drugs issued on prescription by general dental practitioners. Despite this there remains little evidence-based literature on what should be prescribed for any given clinical situation, at what dosage and for how long. Given the current climate of evidence-based research, the need to keep antibiotic prescribing to an acceptable minimum, increasing levels of resistance of micro-organisms and widespread hospital infections with 'superbugs', there is a distinct need for appropriate prescribing guidelines. Considering best practice, an extensive review of the literature and a thorough understanding of current empirical treatment regimes, an attempt has been made to recommend suitable antibiotic prescribing for the adult patient suffering from acute dentoalveolar infections based on evidence.
Ellison
S J
SJ
Department of Oral Medicine and Primary Care, Bristol Dental Hospital, Lower Maudlin Street, Bristol. sarah.ellison@uhbristol.nhs.uk
D000208:Acute Disease; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002981:Clindamycin / Q000627:therapeutic use; D004322:Drainage; D024881:Drug Resistance, Bacterial; D004363:Drug Utilization / Q000592:standards*; D055094:Evidence-Based Dentistry; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D010404:Penicillin V / Q000627:therapeutic use; D010482:Periapical Abscess / Q000188:drug therapy* / Q000382:microbiology; D010508:Periodontal Abscess / Q000188:drug therapy* / Q000382:microbiology; D017410:Practice Guidelines as Topic
D000900:Anti-Bacterial Agents; D008795:Metronidazole; D002981:Clindamycin; D000658:Amoxicillin; D010404:Penicillin V