Synthesis of 1,2-diketones by the transition metal-catalyst-free reaction of alpha-oxo acid chlorides or oxalyl chloride with organostannanes.
The reaction of an alpha-oxo acid chloride with an organostannane proceeds transition metal-catalyst-free to afford a 1,2-diketone in an excellent yield. In addition, a sequence comprising pretreatment of oxalyl chloride with an organostannane and a subsequent treatment with another organostannane also works as a convenient modification.
Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan.
Taigo
T
Kashiwabara
Masato
M
Tanaka