Recurrent acute kidney failure due to McArdle disease.
We present an adolescent with McArdle disease and recurrent acute kidney failure due to rhabdomyolysis. The patient was admitted with acute kidney failure for 3 times and due to a history of proximal weakness, fatigue, and muscular cramps after physical activities a glycogen-storage disease was suspected. Serum creatine phosphokinase and urine myoglobin were found to be elevated. McArdle disease was diagnosed based on pathologic examination of muscle tissue specimen. Patients presenting with rhabdomyolysis following strenuous exercise should be evaluated for McArdle disease.
Noshad
Hamid
H
Division of Nephrology, Department of Medicine, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. hamidnoshad1@yahoo.com
Sadreddini
Shahram
S
Ghaffari
Ali Reza
AR
D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000293:Adolescent; D002648:Child; D004576:Electromyography; D006012:Glycogen Storage Disease Type V / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D012008:Recurrence; D006435:Renal Dialysis; D012206:Rhabdomyolysis / Q000209:etiology