Inhibitory effect of total lignan from Fructus Arctii on aldose reductase.
The potent inhibitory effect of the total lignan from the plant Fructus Arctii on aldose reductase was observed, suggesting its preventive potential on diabetic complications upon long term administration.
Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhaohui
Z
Xu
Hongzhou
H
Yang
Mingmei
M
Zhou
Yi
Y
Feng
Wei
W
Jia
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors*; D000818:Animals; D031170:Arctium / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D017705:Lignans / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D004791:Enzyme Inhibitors; D017705:Lignans; D010936:Plant Extracts; D000449:Aldehyde Reductase