Fluorescence image-guided surgery of brain tumors: explained step-by-step.
Fluorescence image-guided surgery (FIGS) and fluorescence-guided resection (FGR) are surgical techniques used to maximise tumor excision and minimise collateral damage. FIGS and FGR combine preoperative photosensitizer-administration and fluorescence detection during surgery, by illumination of the surgical field using the appropriate wavelength and observing the fluorescence via a long-pass filter that allows fluorescent tumor to be seen by the surgeon. Commercially available technology has led to gross total resection of enhancing brain tumors in 65% of patients compared to merely 35% under standard white light surgery. This is a step-by-step synopsis of the techniques of FIGS in brain.
Department of Neurosurgery, Ninewells Hospital and Medical School, Dundee, Scotland, UK. m.s.eljamel@dundee.ac.uk
M Sam
MS
Eljamel
D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*