Monkey malaria kills four humans.
Four human deaths caused by Plasmodium knowlesi, a simian malaria species, are stimulating a surge of public health interest and clinical vigilance in vulnerable areas of Southeast Asia. We, and other colleagues, emphasize that these cases, identified in Malaysia, are a clear warning that health facilities and clinicians must rethink the diagnosis and treatment of malaria cases presumed to be caused by a less virulent human malaria species, Plasmodium malariae.
Galinski
Mary R
MR
Division of Infectious Diseases, Department of Medicine, School of Medicine, Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA. mary.galinski@emory.edu
Barnwell
John W
JW
D000818:Animals; D000852:Anopheles / Q000145:classification / Q000469:parasitology; D002423:Cause of Death; D016054:DNA, Protozoan / Q000032:analysis; D006801:Humans; D007303:Insect Vectors / Q000145:classification / Q000469:parasitology; D008252:Macaca fascicularis / Q000469:parasitology; D008288:Malaria / Q000175:diagnosis / Q000401:mortality* / Q000469:parasitology / Q000635:transmission; D008296:Malaysia / Q000453:epidemiology; D008992:Monkey Diseases / Q000469:parasitology / Q000635:transmission; D016790:Plasmodium knowlesi / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D016133:Polymerase Chain Reaction / Q000379:methods; D014774:Virulence; D015047:Zoonoses / Q000469:parasitology / Q000635:transmission
D016054:DNA, Protozoan