[Acute pancreatitis associated with the administration of ceftriaxone in an adult patient].
We report a case of a 35-year-old patient with acute pancreatitis after administration of ceftriaxone. She was given ceftriaxone (2g/day) for 9 days because of diverticulitis of the colon. She was admitted to our hospital again because of epigastralgia 12 days after the first administration of ceftriaxone. Laboratory examination showed markedly elevated serum amylase, and CT scan demonstrated findings consistent with acute pancreatitis, in addition to sludge in the common bile duct and gall bladder, which was not identified before the administration of ceftriaxone. We should be aware of the fact that administration of ceftriaxone sometimes results in the formation of biliary sludge and can cause severe adverse events such as cholecystitis and pancreatitis, not only in children, but also in adult patients.
Department of Gastroenterology, Kainan Hospital, Japan.
Yumihiko
Y
Sasaki
Sachiko
S
Aoki
Kota
K
Aoki
Koichi
K
Achiwa
Tsuyoki
T
Yama
Minoru
M
Kubota
Daisuke
D
Ishikawa
Tetsuya
T
Mizutani
Shin
S
Kunii
Kazumasa
K
Watanabe
Akihiko
A
Okumura
D000208:Acute Disease; D000328:Adult; D002443:Ceftriaxone / Q000009:adverse effects*; D002764:Cholecystitis / Q000139:chemically induced; D005260:Female; D006801:Humans; D010195:Pancreatitis / Q000139:chemically induced*
D002443:Ceftriaxone