[Cerebral microdialysis. Options and limits].
Cerebral microdialysis (CMD) is a minimal-invasive monitoring technique for patients with subarachnoidal haemorrhage or severe traumatic brain injury, which allows the investigation of a wide spectrum of compounds in the brain tissue. The aim is a precocious identification of cerebral ischemia and secondary brain damage. The method was introduced in the early 1970s. By using commercial equipment it is nowadays possible to conduct on-line analysis at the bedside in the intensive care unit. The following article discusses the principles of CMD, the most commonly used biomarkers and the options during neurointensive care.
Gautschi
Oliver P
OP
Klinik für Neurochirurgie am Kantonsspital St. Gallen. oliver.gautschi@kssg.ch
Seule
Martin
M
Cadosch
Dieter
D
Land
Marc
M
Fournier
Jean-Yves
JY
Hildebrandt
Gerhard
G
D001921:Brain / Q000378:metabolism*; D001930:Brain Injuries / Q000175:diagnosis* / Q000378:metabolism*; D002545:Brain Ischemia / Q000175:diagnosis* / Q000378:metabolism*; D003422:Critical Care / Q000379:methods*; D006801:Humans; D017551:Microdialysis / Q000295:instrumentation* / Q000379:methods* / Q000639:trends