New approach to incorporation of boron in tumor-seeking molecules.
Cyclic oxonium derivatives of polyhedral boron hydrides have great potential for modification of various types of tumor seeking biomolecules and are very promising starting materials for synthesis of BNCT (boron neutron capture therapy) agents.
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street, 119991 Moscow, Russia. sivaev@ineos.ac.ru
I B
IB
Sivaev
A A
AA
Semioshkin
V I
VI
Bregadze
D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D016754:Boron Neutron Capture Therapy / Q000379:methods*; D015195:Drug Design; D006801:Humans; D015394:Molecular Structure; D009369:Neoplasms / Q000532:radiotherapy*; D011838:Radiation-Sensitizing Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use
D001896:Boron Compounds; D011838:Radiation-Sensitizing Agents