Dural venous thrombosis following splenectomy in a patient with hereditary spherocytosis.
Hereditary spherocytosis is a common form of hemolytic anemia sometimes requiring splenectomy in recalcitrant cases. The complications of splenectomy include an increased risk of thrombosis, usually presenting with deep vein thrombosis or pulmonary embolism. However, common complaints such as headache should warn clinicians of involvement in less common sites, primarily the dural venous system. The case of dural venous thrombosis in a patient with hereditary spherocytosis and splenectomy is discussed. The potential mechanisms associated with thrombosis formation in this population and its treatment are discussed.
Perkins
Linda A
LA
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of South Carolina, Eight Medical Park, Columbia, SC 29203, USA. Linda.Perkins@uscmed.sc.edu
Jones
Shirley F
SF
Bhargava
Ranjana S
RS
D002533:Cerebral Angiography; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D013103:Spherocytosis, Hereditary / Q000150:complications* / Q000601:surgery; D013156:Splenectomy / Q000009:adverse effects*; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D055815:Young Adult
D005343:Fibrinolytic Agents; D006493:Heparin