Patient satisfaction and clinical outcome after injecting gonadotropins with use of a needle-free carbon dioxide injection system for controlled ovarian hyperstimulation for in vitro fertilization.
In this prospective, randomized clinical trial, we tested the hypothesis that a needle-free CO(2) injection system (Biojector 2000) would be better tolerated by patients when compared with traditional sharp needles used for gonadotropin injections during stimulation for IVF. As measured by our questionnaire, the needle-free CO(2) injection system was not better tolerated by patients, even though it was equally effective clinically.
Solnica
Amy
A
New Jersey Medical School/University of Medicine and Dentistry of New Jersey, Newark, New Jersey.
Oh
Cheongeun
C
New York University School of Medicine, Department of Environmental Medicine, New York, New York.
Cho
Michael M
MM
New Jersey Medical School/University of Medicine and Dentistry of New Jersey, Newark, New Jersey; University Reproductive Associates, Hasbrouck Heights, New Jersey.
Loughlin
Jacquelyn S
JS
New Jersey Medical School/University of Medicine and Dentistry of New Jersey, Newark, New Jersey; University Reproductive Associates, Hasbrouck Heights, New Jersey.
McCulloh
David H
DH
New Jersey Medical School/University of Medicine and Dentistry of New Jersey, Newark, New Jersey; University Reproductive Associates, Hasbrouck Heights, New Jersey.
McGovern
Peter G
PG
New Jersey Medical School/University of Medicine and Dentistry of New Jersey, Newark, New Jersey; University Reproductive Associates, Hasbrouck Heights, New Jersey. Electronic address: mcgovepg@umdnj.edu.
D002245:Carbon Dioxide; D005239:Fear; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006062:Gonadotropins / Q000008:administration & dosage*; D006801:Humans; D007260:Infusion Pumps / Q000523:psychology; D007279:Injections, Subcutaneous / Q000523:psychology; D009339:Needles; D010062:Ovulation Induction / Q000379:methods* / Q000523:psychology; D017060:Patient Satisfaction; D011247:Pregnancy; D018873:Pregnancy Rate; D016896:Treatment Outcome
D006062:Gonadotropins; D002245:Carbon Dioxide