New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
The Global Alliance to Improve Outcomes in Acne published recommendations for the management of acne as a supplement to the Journal of the American Academy of Dermatology in 2003. The recommendations incorporated evidence-based strategies when possible and the collective clinical experience of the group when evidence was lacking. This update reviews new information about acne pathophysiology and treatment-such as lasers and light therapy-and relevant topics where published data were sparse in 2003 but are now available including combination therapy, revision of acne scarring, and maintenance therapy. The update also includes a new way of looking at acne as a chronic disease, a discussion of the changing role of antibiotics in acne management as a result of concerns about microbial resistance, and factors that affect adherence to acne treatments. Summary statements and recommendations are provided throughout the update along with an indication of the level of evidence that currently supports each finding. As in the original supplement, the authors have based recommendations on published evidence as much as possible.
Thiboutot
Diane
D
Department of Dermatology, Pennsylvania State University College of Medicine, Hershey, USA. dthiboutot@psu.edu
Gollnick
Harald
H
Bettoli
Vincenzo
V
Dréno
Brigitte
B
Kang
Sewon
S
Leyden
James J
JJ
Shalita
Alan R
AR
Lozada
Vicente Torres
VT
Berson
Diane
D
Finlay
Andrew
A
Goh
Chee Leok
CL
Herane
María Isabel
MI
Kaminsky
Ana
A
Kubba
Raj
R
Layton
Alison
A
Miyachi
Yoshiki
Y
Perez
Montserrat
M
Martin
Jaime Piquero
JP
Ramos-E-Silva
Marcia
M
See
Jo Ann
JA
Shear
Neil
N
Wolf
John
J
D000152:Acne Vulgaris / Q000209:etiology / Q000628:therapy*; D000284:Administration, Oral; D000287:Administration, Topical; D000465:Algorithms; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D006801:Humans; D007627:Keloid / Q000628:therapy; D010789:Phototherapy; D012176:Retinoids / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D012176:Retinoids