An antibacterial and antifungal phenylpropanoid from Carum montanum (Coss. et Dur.) Benth. et Hook.
The volatile constituents of the aerial parts of Carum montanum (Coss. et Dur.) Benth. et Hook. were analysed by GC-FID and GC-MS, and the main component was isolated and identified as nothoapiole. The antibacterial and antifungal activities of this compound and of the total oil were investigated against Gram-negative (P. aeruginosa, E. coli), Gram-positive (E. faecalis, S. aureus, S. epidermitis, S. saprophyticus, S. simulans, S. lugdunensis) bacteria and on one strain of fungus (C. tropicalis).
Department of Biology, University of Setif, Mabouda, 19000, Setif, Algeria.
Hocine
H
Laouer
El Kolli
el K
Meriem
Soizic
S
Prado
Nicolas
N
Baldovini
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D041022:Candida tropicalis / Q000187:drug effects; D029974:Carum / Q000737:chemistry*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009822:Oils, Volatile / Q000494:pharmacology; D010666:Phenylpropionates / Q000302:isolation & purification / Q000494:pharmacology*; D010938:Plant Oils / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009822:Oils, Volatile; D010666:Phenylpropionates; D010938:Plant Oils; C546523:nothoapiole