Spirometry, impulse oscillometry and capnovolumetry in welders and healthy male subjects.
BACKGROUND
Welding processes emit fine and ultrafine aerosol particles which are potentially harmful to the lungs of welders. In the past, changes in lung function were mostly determined by conventional spirometry. In this study spirometry was combined with new techniques such as Impulse Oscillometry (IOS) and Capnovolumetry (CVS) in order to assess welding associated changes in lung function.


METHODS
45 Male welders and 24 non-welders were investigated at two time points: before work shift (baseline) and after work shift.


RESULTS
At baseline there were no differences between both study populations in spirometric, IOS, and CVS parameters. However, parameters of the flow-volume curve decreased with increasing long-term welding fume exposure (welding years). Airway resistances measured by IOS increased with welding years. IOS central airway resistance and several parameters of CVS increased during the work shift indicating airway narrowing and more inhomogeneous ventilation.


CONCLUSIONS
In this study it has been shown that welding associated long-term and short-term effects could be detected in a population of welders, although exposure conditions were quite heterogeneous. The parameters of IOS and Capnovolumetry showed effects even more pronounced than conventional lung function parameters. Thus, these techniques may be considered as an additional tool for occupational medicine research.
Gube
Monika
M
RWTH Aachen University, Institute for Occupational and Social Medicine, Pauwelsstrasse 30, Aachen, Germany.
Brand
Peter
P
Conventz
Angela
A
Ebel
Joachim
J
Goeen
Thomas
T
Holzinger
Karl
K
Müller-Lux
Alice
A
Reisgen
Uwe
U
Schettgen
Thomas
T
Kraus
Thomas
T
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000139:chemically induced / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000503:physiopathology*; D016273:Occupational Exposure / Q000009:adverse effects; D009991:Oscillometry / Q000379:methods; D012129:Respiratory Function Tests / Q000379:methods*; D013147:Spirometry / Q000379:methods; D014896:Welding; D017132:Workplace; D055815:Young Adult
D000395:Air Pollutants, Occupational