Induction of histone acetylation on the sucrase-isomaltase gene in the postnatal rat jejunum.
The rapid induction of the sucrase-isomaltase (SI) gene in rat jejunum from the onset to final period of weaning was associated with increases of the acetylation of histones H3 and H4 on the promoter/transcriptional region of the gene, suggesting that an abrupt jejunal induction of histone acetylation changes on the SI gene during this period may be concerned with the expression of the gene.
Laboratory of Nutritional Physiology, Graduate School of Nutritional and Environmental Sciences, Global COE Program, The University of Shizuoka, Shizuoka 422-8526, Japan.
Satoko
S
Yorita
Kazuki
K
Mochizuki
Toshinao
T
Goda
D000107:Acetylation; D000818:Animals; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006657:Histones / Q000378:metabolism*; D007583:Jejunum / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013394:Sucrase-Isomaltase Complex / Q000235:genetics*; D015533:Transcriptional Activation
D006657:Histones; D013394:Sucrase-Isomaltase Complex