The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Mucositis: from febrile neutropenia to febrile mucositis.
The treatment of patients with cancer is often accompanied by life-threatening complications caused by chemotherapy and radiotherapy. They are known to result from neutropenia, but damage to the mucosal barrier as well as the humoral and cellular immune defences play a significant role in various infectious complications and aggravate diverse inflammatory processes. The article describes the journey from febrile neutropenia to febrile mucositis in patients treated with immunocompromising therapy.
Blijlevens
Nicole M A
NM
Department of Haematology, Radboud University Medical Center, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands. N.Blijlevens@hemat.umcn.nl
Logan
Richard M
RM
Netea
Mihai G
MG
D019090:Case Management; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D052016:Mucositis / Q000175:diagnosis* / Q000628:therapy*; D009503:Neutropenia / Q000150:complications*
D007166:Immunosuppressive Agents