[Ischemic heart disease].
It has been reported that antihypertensive therapy reduces the risk of ischemic heart disease. Except for the antihypertensive effects, the angiotensin converting enzyme (ACE) inhibitors are proved to be very effective in primary and secondary event onset prophylaxis by many clinical trials. The angiotensin II receptor antagonists (ARBs) used briskly in recent years inhibits angiotensin II type 1 receptor alternatively. Although ARBs protect organs, especially blood vessel, heart, brain and kidney in sites of pharmacology, ARBs are still not much as effective results as ACE inhibitors for the patients with ischemic heart disease, by many clinical trials.
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University.
Megumi
M
Yamamuro
Hisao
H
Ogawa
D057911:Angiotensin Receptor Antagonists; D002986:Clinical Trials as Topic; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy*
D057911:Angiotensin Receptor Antagonists