Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis.
CONCLUSIONS
The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.


BACKGROUND
The FALCOR rate calculator is currently accessible at http://www.mitochondria.org/protocols/FALCOR.html. This program is written as a Java Applet, requiring a web browser enabled with Sun MicroSystems' Java Virtual Machine.
Department of Cancer Genetics, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA. brandon.hall@roswellpark.org
Brandon M
BM
Hall
Chang-Xing
CX
Ma
Ping
P
Liang
Keshav K
KK
Singh
D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D020407:Internet; D016013:Likelihood Functions; D009154:Mutation / Q000235:genetics*; D012984:Software