hMG increases the yield of mature oocytes and excellent-quality embryos in patients with a previous cycle having a high incidence of oocyte immaturity.
In a selected group of patients with >20% oocyte immaturity during an IVF cycle with FSH alone, the addition of hMG to the stimulation protocol results in a higher yield of mature oocytes and excellent-quality embryos.
Center for Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California. Electronic address: huddlestonh@obgyn.ucsf.edu.
Heather G
HG
Huddleston
Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Katharine V
KV
Jackson
Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Joseph O
JO
Doyle
Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Catherine
C
Racowsky
D000328:Adult; D015331:Cohort Studies; D004359:Drug Therapy, Combination; D004622:Embryo, Mammalian / Q000187:drug effects*; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology* / Q000627:therapeutic use*; D005640:Follicle Stimulating Hormone / Q000494:pharmacology / Q000627:therapeutic use; D006728:Hormones / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D007986:Luteinizing Hormone / Q000494:pharmacology / Q000627:therapeutic use; D008596:Menotropins / Q000494:pharmacology* / Q000627:therapeutic use*; D008597:Menstrual Cycle / Q000187:drug effects; D009865:Oocytes / Q000166:cytology / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome
D005300:Fertility Agents, Female; D006728:Hormones; D008596:Menotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone