[Fuzzy mathematic quantitative law of composing principle in the study of traditional Chinese medicine].
This study is to analyze microcosmic significance of Chinese medicine composing principle "principal, assistant, complement and mediating guide" and it's fuzzy mathematic quantitative law. According to molecular biology and maximal membership principle, fuzzy subset and membership functions were proposed. Using in vivo experiment on the effects of SiWu Decoction and its ingredients on mice with radiation-induced blood deficiency, it is concluded that DiHuang and DangGui belonged to the principal and assistant subset, BaiShao belonged to the contrary complement subset, ChuanXiong belonged to the mediating guide subset by maximal membership principle. It is discussed that traditional Chinese medicine will be consummate medical science when its theory can be described by mathematic language.
Liu
Ming
M
Institute of Radiation and Irradiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China.
Gao
Yue
Y
Xiao
Rui
R
Zhang
Bo-li
BL
D000818:Animals; D003114:Colony-Forming Units Assay; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D015672:Erythroid Precursor Cells / Q000187:drug effects; D017143:Fuzzy Logic; D055014:Granulocyte-Macrophage Progenitor Cells / Q000187:drug effects; D007962:Leukocytes / Q000187:drug effects; D008433:Mathematics; D008516:Medicine, Chinese Traditional; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D025341:Principal Component Analysis / Q000379:methods; D011833:Radiation Injuries, Experimental / Q000097:blood*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C403258:si-wu-tang