Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2).
The objective of the present research was to develop a single measure of the major symptoms of both neuropathic and non-neuropathic pain that can be used in studies of epidemiology, natural history, pathophysiologic mechanisms, and treatment response. We expanded and revised the Short-form McGill Pain Questionnaire (SF-MPQ) pain descriptors by adding symptoms relevant to neuropathic pain and by modifying the response format to a 0-10 numerical rating scale to provide increased responsiveness in longitudinal studies and clinical trials. The reliability, validity, and subscale structure of the revised SF-MPQ (SF-MPQ-2) were examined in responses from 882 individuals with diverse chronic pain syndromes and in 226 patients with painful diabetic peripheral neuropathy who participated in a randomized clinical trial. The data suggest that the SF-MPQ-2 has excellent reliability and validity, and the results of both exploratory and confirmatory factor analyses provided support for four readily interpretable subscales-continuous pain, intermittent pain, predominantly neuropathic pain, and affective descriptors. These results provide a basis for use of the SF-MPQ-2 in future clinical research, including clinical trials of treatments for neuropathic and non-neuropathic pain conditions.
Dworkin
Robert H
RH
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA. robert_dworkin@urmc.rochester.edu
Turk
Dennis C
DC
Revicki
Dennis A
DA
Harding
Gale
G
Coyne
Karin S
KS
Peirce-Sandner
Sarah
S
Bhagwat
Dileep
D
Everton
Dennis
D
Burke
Laurie B
LB
Cowan
Penney
P
Farrar
John T
JT
Hertz
Sharon
S
Max
Mitchell B
MB
Rappaport
Bob A
BA
Melzack
Ronald
R
D000368:Aged; D003929:Diabetic Neuropathies; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D010147:Pain Measurement / Q000379:methods* / Q000592:standards*; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires / Q000592:standards*