Database of queryable gene expression patterns for Xenopus.
The precise localization of gene expression within the developing embryo, and how it changes over time, is one of the most important sources of information for elucidating gene function. As a searchable resource, this information has up until now been largely inaccessible to the Xenopus community. Here, we present a new database of Xenopus gene expression patterns, queryable by specific location or region in the embryo. Pattern matching can be driven either from an existing in situ image, or from a user-defined pattern based on development stage schematic diagrams. The data are derived from the work of a group of 21 Xenopus researchers over a period of 4 days. We used a novel, rapid manual annotation tool, XenMARK, which exploits the ability of the human brain to make the necessary distortions in transferring data from the in situ images to the standard schematic geometry. Developmental Dynamics 238:1379-1388, 2009. (c) 2009 Wiley-Liss, Inc.
Gurdon Institute, Cambridge University, Cambridge, United Kingdom. m.gilchrist@gurdon.cam.ac.uk
Michael J
MJ
Gilchrist
Mikkel B
MB
Christensen
Odile
O
Bronchain
Frédéric
F
Brunet
Albert
A
Chesneau
Ursula
U
Fenger
Timothy J
TJ
Geach
Holly V
HV
Ironfield
Ferdinand
F
Kaya
Sadia
S
Kricha
Robert
R
Lea
Karine
K
Massé
Isabelle
I
Néant
Elodie
E
Paillard
Karine
K
Parain
Muriel
M
Perron
Ludivine
L
Sinzelle
Jacob
J
Souopgui
Raphaël
R
Thuret
Qods
Q
Ymlahi-Ouazzani
Nicolas
N
Pollet
D000818:Animals; D030541:Databases, Genetic; D015870:Gene Expression; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D012984:Software; D014982:Xenopus laevis / Q000033:anatomy & histology / Q000196:embryology* / Q000235:genetics*