Clinical consensus conference: survey on Gram-positive bloodstream infections with a focus on Staphylococcus aureus.
The increased incidence over the past decade of bloodstream infections (BSIs) caused by gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus, highlights the critical need for a consistent approach to therapy. However, there is currently no international consensus on the diagnosis and management of gram-positive BSIs. The Clinical Consensus Conference on Gram-Positive Bloodstream Infections was convened as a session at the 9th International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections held in 2007. Participants discussed various aspects of the practical treatment of patients who present with gram-positive BSI, including therapeutic options for patients with BSIs of undefined origin, the selection of appropriate empirical therapy, and treatment of complicated and uncomplicated BSIs. The opinions of participants about these key issues are reflected in this article.
Naber
Christoph K
CK
Department of Cardiology, West-German Heart Center, Essen, Germany. cknaber@web.de
Baddour
Larry M
LM
Giamarellos-Bourboulis
Evangelos J
EJ
Gould
Ian M
IM
Herrmann
Mathias
M
Hoen
Bruno
B
Karchmer
Adolf W
AW
Kobayashi
Yoshio
Y
Kozlov
Roman S
RS
Lew
Daniel
D
Miró
José M
JM
Moellering
Robert C
RC
Moreillon
Philippe
P
Peters
Georg
G
Rubinstein
Ethan
E
Seifert
Harald
H
Corey
G Ralph
GR
D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D011795:Surveys and Questionnaires