Crohn's disease of the pouch: diagnosis and management.
Approximately 30% of patients with ulcerative colitis will eventually require surgery. Ileal pouch-anal anastomosis has become the surgical treatment of choice in ulcerative colitis patients with refractory disease or dysplasia who require proctocolectomy. A subset of patients with ileal pouches may develop Crohn's disease or a Crohn's disease-like condition of the pouch after the surgery. Diagnosis and management can be challenging. A combined assessment of endoscopy, histology, radiographic imaging and examination under anesthesia is often necessary for an accurate diagnosis, disease classification, management and prognosis. A multidisciplinary approach by a medical and surgical team, together with experienced pathologists and radiologists, is advocated.
Wu
Hao
H
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China.
Shen
Bo
B
D039021:Colonic Pouches; D003424:Crohn Disease / Q000175:diagnosis* / Q000601:surgery*; D003937:Diagnosis, Differential; D006801:Humans; D016737:Proctocolectomy, Restorative; D011379:Prognosis