Adrenal insufficiency secondary to tuberculosis: the value of telemedicine in the remote diagnosis of Addison's disease in Ebeye, Republic of the Marshall Islands.
A young Marshallese woman presented with the insidious development of fever, cough, fatigue, profound weakness, massive weight loss, cachexia, alopecia, amenorrhea, and periumbilical hyperpigmentation. Limited laboratory studies revealed anemia, leukocytosis, and hyponatremia. Imaging studies, as well as digital photographs, transmitted over the Internet, using the secure Pacific Island Health Care Project (PIHCP), store-and-forward telemedicine system, suggested the diagnosis of disseminated tuberculosis, and antimycobacterial antibiotics were begun. Sputum cultures eventually grew Mycobacterium tuberculosis. Based on the constellation of clinical signs and symptoms, the transmitted images, and limited laboratory data, adrenal tuberculosis (Addison's disease) with adrenal insufficiency was diagnosed and corticosteroids were initiated. The patient responded dramatically This case underscores the utility of telemedicine in the diagnosis and treatment of patients with unusual conditions, rarely seen today in the United States, from remote sites in the Developing World.
Tripler Army Medical Center, Honolulu, HI 96859, USA.
Lisabeth A
LA
Bush
Lynne
L
Ruess
Tom
T
Jack
Donald A
DA
Person
D000224:Addison Disease / Q000188:drug therapy / Q000209:etiology*; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008849:Micronesia; D017216:Telemedicine / Q000458:organization & administration*; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy; D055815:Young Adult
D000995:Antitubercular Agents; D005938:Glucocorticoids