F-18 FDG PET-CT imaging in recurrent cerebral gliosarcoma.
We report the F-18 FDG PET-CT appearance of recurrent gliosarcoma (GS) with extracranial extension in a 47-year-old man who underwent surgical resection of a right frontal GS 5 months earlier. F-18 FDG PET demonstrated moderate uptake in the recurrent disease. GS is a very rare, biphasic primary neoplasm of the central nervous system, composed of glioblastoma multiforme mixed with a sarcomatous component. It occurs in adults of middle age and carries a poor prognosis. The median survival reported is less than a year. The results suggest that F-18 FDG PET imaging may be useful in detecting recurrent GS.
Department of Radiology, Division of Nuclear Medicine, PET Imaging Science Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA. linhho@usc.edu
Linh Thuy
LT
Ho
Heidi
H
Wassef
Robert
R
Henderson
John
J
Seto
D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D019788:Fluorodeoxyglucose F18; D018316:Gliosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012008:Recurrence; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18