Chemical characterization of the lipophilic fraction of Livistona decipiens and Livistona chinensis fruit pulps (Palmae) and assessment of their anti-hyperlipidemic and anti-ulcer activities.
The oil of the dried pulps of Livistona decipiens and L. chinensis palm fruits have been studied for the first time by gas chromatography-mass spectrometry for their unsaponifiable matter (USM) and fatty acid composition (FAME). The antihyperlipidemic and anti-ulcer activities for both oils were also assayed. The principal fatty acid of L. decipiens pulp oil was oleic acid (53.4 %) and of L. chinensis pulp oil palmitic acid (47.4 %). In relation to anti-hyperlipidemic properties, the pulp oil of L. decipiens presented a better profile than that of L. chinensis, in comparison with the reference standard (simvastatin). In addition, both pulp oils showed high anti-ulcer activity using an indomethacin-induced ulceration technique in rat stomach. The relationship between the anti-hyperlipidemic, anti-ulcer and chemical composition of the pulp oils is also discussed.
Kadry
Hazem
H
Department of Pharmacognosy, Faculty of Pharmacy, Nasr City 1137, Al Azhar University, Cairo, Egypt.
Shoala
Soha
S
El Gindi
Omayma
O
Sleem
Amany A
AA
Mosharrafa
Salwa
S
Kassem
Mona
M
D000818:Animals; D000897:Anti-Ulcer Agents / Q000737:chemistry* / Q000494:pharmacology; D028023:Arecaceae / Q000737:chemistry*; D004041:Dietary Fats; D005638:Fruit / Q000737:chemistry*; D006949:Hyperlipidemias / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000494:pharmacology*; D007213:Indomethacin / Q000633:toxicity; D008055:Lipids / Q000097:blood; D008297:Male; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy
D000897:Anti-Ulcer Agents; D004041:Dietary Fats; D000960:Hypolipidemic Agents; D008055:Lipids; D010936:Plant Extracts; D007213:Indomethacin