[Effect of Alinamin F and Kakkontou on mucoid Pseudomonas aeruginosa chronic lower respiratory tract infection].
In a 78-year-old woman with chronic respiratory tract infection caused by Pseudomonas aeruginosa with a mucoid phenotype, the organism was eliminated from the sputum by use of Kakkontou (Chinese herbal drug) and Alinamin F (Fursultiamine). Gram staining of a sputum smear showed mucoid micro-organisms were engulfed by neutrophils. Both drugs could change the mucoid character of this microorganism. It was suggested that polymorphonuclear leukocytes activated by Kakkontou could recognize this organism as a foreign body because of the changed mucoid character, and cleared it by phagocytosis.
Irifune
Kenji
K
Irifune Clinic.
D000368:Aged; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy*; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013831:Thiamine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D004365:Drugs, Chinese Herbal; C090831:kakkon-to; C013294:prosultiamine; D013831:Thiamine