Myostatin and muscle fiber size. Focus on "Smad2 and 3 transcription factors control muscle mass in adulthood" and "Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size".
Stephen L
SL
Welle
D000818:Animals; D002454:Cell Differentiation; D048429:Cell Size; D006801:Humans; D024510:Muscle Development; D018485:Muscle Fibers, Skeletal / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D009133:Muscular Atrophy / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D055435:Myostatin / Q000378:metabolism*; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D038762:Ribosomal Protein S6 Kinases, 70-kDa / Q000378:metabolism; D015398:Signal Transduction; D051899:Smad2 Protein / Q000378:metabolism; D051900:Smad3 Protein / Q000378:metabolism; D058570:TOR Serine-Threonine Kinases
D055435:Myostatin; D051899:Smad2 Protein; D051900:Smad3 Protein; D011494:Protein Kinases; C546842:MTOR protein, human; D051057:Proto-Oncogene Proteins c-akt; D038762:Ribosomal Protein S6 Kinases, 70-kDa; D058570:TOR Serine-Threonine Kinases