Youth of west-Cameroon are at high risk of developing IDD due to low dietary iodine and high dietary thiocyanate.
BACKGROUND
Hypothyroidism in utero leading to mental retardation is highly prevalent in developing countries where iodine deficiency and thiocyanate overload are combined.


OBJECTIVE
To explore prevalence of IDD in Bamougoum, a mountain region of western Cameroon, by studying urinary iodine and thiocyanate excretion levels in children.


METHODS
Bamougoum district in western Cameroon was selected for closer study due to its geographic location predisposing to iodine deficiency disorders (IDD). A comprehensive sampling strategy included 24-h urine samples collected over three days from 120 school-aged children. Urinary iodine and thiocyanate levels were measured by colorimetric methods.


RESULTS
Twenty one percent of boys between the ages 3 and 19 were classified as iodine deficient. The prevalence of thiocyanate overload in the same population was found to be 20%.


CONCLUSIONS
Presence of endemic iodine deficiency and excessive thiocyanate in the population indicates that the region is at risk of iodine deficiency disorder. A multifactorial approach that includes improvement of diet, increasing iodine and minimizing goitrogen substances intake, soil and crop improvement and an iodine supplementation program may help alleviate IDD in the affected area studied.
Clinical Biochemistry and Nutrition Unit, Biochemistry Dept, Faculty of Sciences, PO Box 24157 Dla, University of Douala, Cameroon. tagibra@yahoo.fr
Ibrahim
I
Taga
Valere Aime Soh
VA
Oumbe
Robert
R
Johns
Mohsin Abbas
MA
Zaidi
Jeanne Ngogang
JN
Yonkeu
Illimar
I
Altosaar
D000293:Adolescent; D017677:Age Distribution; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003124:Colorimetry / Q000379:methods; D003409:Congenital Hypothyroidism / Q000453:epidemiology*; D004032:Diet; D005260:Female; D006801:Humans; D007455:Iodine / Q000172:deficiency / Q000652:urine*; D008297:Male; D009752:Nutritional Status; D011159:Population Surveillance; D015995:Prevalence; D012306:Risk; D013861:Thiocyanates / Q000652:urine*; D055815:Young Adult
D013861:Thiocyanates; D007455:Iodine