[Diagnostic value of determination of serum enzyme activities in patients with gastrointestinal lesions caused by caustic substances].
Examination of 101 patients with pathological processes induced by caustic substances included measurement of serum enzyme activities (lactate dehydrogenase, creatine phosphokinase, aminotransferase , alkaline phosphatase), De Ritis index, and free hemoglobin. It was found that caustic lesions in splanchnic organs were associated with enhanced enzymatic activities the spectra of which were different in patients with acetic acid poisoning and poisoning from other caustic substances (inorganic acids, alkalis, oxidizing agents). It is concluded that a rise in creatine phosphokinase activity may be used as an indicator of the severity of lesion in the walls of the digestive tract.
S Kh
SKh
Sarmanaev
D000469:Alkaline Phosphatase / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002424:Caustics / Q000009:adverse effects*; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000201:enzymology; D041981:Gastrointestinal Tract / Q000187:drug effects / Q000473:pathology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D015203:Reproducibility of Results; D013053:Spectrophotometry; D000637:Transaminases / Q000097:blood*
D015415:Biomarkers; D002424:Caustics; D007770:L-Lactate Dehydrogenase; D000637:Transaminases; D003402:Creatine Kinase; D000469:Alkaline Phosphatase