Drug testing by chemical analysis of fingerprint deposits from methadone-maintained opioid dependent patients using UPLC-MS/MS.
Chemical analysis of fingerprint deposits from methadone-maintained opioid-dependent patients by UPLC-MS/MS show detectable levels of methadone and its metabolite, EDDP, demonstrating intake of the drug.
Pharmaceutical Sciences Research Division, King's College London, London SE1 9NH, UK.
Shana
S
Jacob
Sue
S
Jickells
Kim
K
Wolff
Norman
N
Smith
D002853:Chromatography, Liquid; D003878:Dermatoglyphics; D006801:Humans; D008691:Methadone / Q000032:analysis* / Q000493:pharmacokinetics; D009294:Narcotics / Q000032:analysis / Q000493:pharmacokinetics; D009293:Opioid-Related Disorders / Q000534:rehabilitation; D011759:Pyrrolidines / Q000032:analysis / Q000493:pharmacokinetics; D015813:Substance Abuse Detection / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods
D009294:Narcotics; D011759:Pyrrolidines; D008691:Methadone; C010724:2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine