Boswellic acids: a group of medicinally important compounds.
This review, containing over 276 references, covers the progress made in the chemistry and bioactivity of this important group of triterpenoids. Though initially known for their anti-inflammatory and anti-arthritic activities through a unique 5-LO inhibition mechanism, boswellic acids have recently attained significance due to their anti-cancer properties. The phytochemistry and chemical modifications, including mechanism of action, are discussed.
Shah
Bhahwal Ali
BA
Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu Tawi, 180001, India.
Qazi
Ghulam Nabi
GN
Taneja
Subhash Chandra
SC
D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001168:Arthritis / Q000188:drug therapy*; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D001688:Biological Products; D014315:Triterpenes; C054625:boswellic acid