[Two cases of transfusion-related acute lung injury following massive transfusion during the perioperative period].
Transfusion-related acute lung injury (TRALI) is a serious complication of transfusion of blood and blood components. TRALI is reported to be the most common cause of transfusion-associated death. TRALI has increasingly become known in the medical community. However, TRALI has been overlooked frequently because of poor knowledge of medical staffs. We report two cases of TRALI after massive transfusion due to massive bleeding during cardiovascular surgery. In the perioperative period, the diagnosis of TRALI is difficult to make because of coexistence of various factors leading to hypoxia. Thus, in this report, we discuss the management of these two cases focusing upon the differential diagnosis of TRALI.
Intensive Care Unit, Osaka University Hospital, Osaka 565-0871.
Seitetsu
S
Kanemura
Noriyuki
N
Ohta
Hidenori
H
Yamanaka
Ryoko
R
Takahashi
Osamu
O
Hirao
Akinori
A
Uchiyama
Yuji
Y
Fujino
Takashi
T
Mashimo
D055371:Acute Lung Injury / Q000175:diagnosis / Q000209:etiology*; D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical; D013504:Cardiovascular Surgical Procedures; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D019990:Perioperative Care / Q000009:adverse effects*; D065227:Transfusion Reaction