Ultra-small water-dispersible fluorescent chitosan nanoparticles: synthesis, characterization and specific targeting.
A robust water-in-oil microemulsion method of making water-dispersible ultra-small (<30 nm) size fluorescent chitosan nanoparticles is reported for the first time and specific targeting of these FCNPs to human leukemia cells via aptamer recognition is demonstrated.
NanoScience Technology Center, University of Central Florida, Orlando, FL 32826, USA.
Padmavathy
P
Tallury
Soumitra
S
Kar
Suwussa
S
Bamrungsap
Yu-Fen
YF
Huang
Weihong
W
Tan
Swadeshmukul
S
Santra
D045744:Cell Line, Tumor; D048271:Chitosan / Q000138:chemical synthesis* / Q000737:chemistry; D005434:Flow Cytometry; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D014867:Water / Q000737:chemistry*
D005456:Fluorescent Dyes; D014867:Water; D048271:Chitosan