[Primary ciliary dyskinesia. A case report and comparison with 4 previous cases].
We encountered a 59-year-old man, whose chief complaints were sputum and dyspnea on effort. He had suffered from sinusitis since childhood, and chest computed tomography showed bronchiectasis. Electron microscopic examination of bronchial mucosa biopsied by bronchoscopy showed defect of the inner dynein arm in most of his cilia. We diagnosed primary ciliary dyskinesia. Seminal analysis showed no abnormalities, and the etiology of infertility remains unclear. The present case is the fifth case treated at our hospital. In this paper, we compared this case with 4 cases (2 cases of Kartagener's syndrome and 2 cases of primary ciliary dyskinesia without situs invertus) of our hospital, and findings of previous reports. Primary ciliary dyskinesia should be included in the differential diagnosis even in cases of mild bronchiectasis or normal mobility of sperm. Primary ciliary dyskinesia has more variety in radiological and clinical findings than has been recognized.
Ishiguro
Takashi
T
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center.
Takayanagi
Noboru
N
Hijikata
Naoya
N
Yoshii
Yutaka
Y
Yoneda
Koichiro
K
Miyahara
Yousuke
Y
Kagiyama
Naho
N
Yano
Ryozo
R
Tokunaga
Daido
D
Aoki
Fumiaki
F
Saito
Hiroo
H
Ubukata
Mikio
M
Kurashima
Kazuyoshi
K
Yanagisawa
Tsutomu
T
Sugita
Yutaka
Y
Kawabata
Yoshinori
Y
D000328:Adult; D002925:Ciliary Motility Disorders / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged