Iridium catalysis for C-H bond arylation of heteroarenes with iodoarenes.
Efficient couplings using equimolar quantities of each coupling partner and multiple C-H bond arylation reactions are achieved with an Ir-based catalytic system for the C-H bond arylation of electron-rich heteroarenes with iodoarenes to construct extended pi-systems. The dramatic ligand effect on reaction efficiency leads to the discovery that Crabtree's catalyst (see scheme) is the optimal catalyst precursor.
Department of Chemistry, Graduate School of Science, Nagoya University, and PRESTO Science and Technology Agency, Chikusa, Nagoya 464-8602, Japan.
Benoît
B
Join
Takuya
T
Yamamoto
Kenichiro
K
Itami
D001688:Biological Products / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D006860:Hydrogen Bonding; D007455:Iodine / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*
D001688:Biological Products; D007495:Iridium; D002244:Carbon; D007455:Iodine