Deriving principles of microbiology by multiscaling laws of molecular physics.
It has long been an objective of the physical sciences to derive principles of biology from the laws of physics. At the angstrom scale for processes evolving on timescales of 10(-14) s, many systems can be characterized in terms of atomic vibrations and collisions. In contrast, biological systems display dramatic transformations including self-assembly and reorganization from one cell phenotype to another as the microenvironment changes. We have developed a framework for understanding the emergence of living systems from the underlying atomic chaos.
Center for Cell and Virus Theory, Department of Chemistry, Indiana University, Bloomington, 47405, USA. ortoleva@indiana.edu
Peter
P
Ortoleva
P
P
Adhangale
S
S
Cheluvaraja
Max
M
Fontus
Zeina
Z
Shreif
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D008827:Microbiological Phenomena; D008829:Microbiology; D008954:Models, Biological; D053769:Nanocapsules; D036103:Nanotechnology; D010825:Physics; D012984:Software
D053769:Nanocapsules