Planning a serial dilution test with multiple dilutions.
The dilutions used in a serial dilution test determine which concentrations it can estimate well. Two criteria help to select how many and which dilutions to use. The first criterion is a low probability of outcomes with either all growth or all non-growth tubes at the concentrations of interest. The second criterion considers how far the estimated concentration (MPN) is likely to be from the actual concentration.
Food and Drug Administration, Center for Applied Nutrition and Food Safety, 5100 Paint Branch Parkway, College Park, MD 20740, USA. robert.blodgett@fda.hhs.gov
Robert J
RJ
Blodgett
D001419:Bacteria / Q000254:growth & development*; D015169:Colony Count, Microbial / Q000379:methods*; D003470:Culture Media / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D011336:Probability; D012692:Serial Passage
D003470:Culture Media