The cytology of a thyroid granular cell tumor.
Granular cell tumor (GCT) of the thyroid is rare. Before this report, only four cases of thyroid GCT have been reported, none of which presented a cytopathological examination. In this paper, we report the fine needle aspiration cytology and pathological analysis of a thyroid GCT from a 12-year-old girl who presented with a painless neck mass. The tumor cells were single, in syncytial clusters, or pseudofollicles, contained small round, oval, or spindle nuclei, indistinct nucleoli, and a large amount of grayish, granular fragile cytoplasm. The background contained granular debris and naked nuclei. A differential diagnosis of thyroid GCT with more frequent thyroid lesions containing cytoplasmic granules, including Hurthle cells, macrophages, follicular cells, and cells of black thyroid syndrome, was also performed.
Chang
Shu-Mei
SM
Department of Anatomic Pathology, Buddhist Dalin Tzu Chi General Hospital, 2, Min-Sheng Rd Dalin Town, Chiayi, Taiwan.
Wei
Chang-Kuo
CK
Tseng
Chih-En
CE
D044963:Biopsy, Fine-Needle / Q000379:methods; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology*; D006801:Humans; D008264:Macrophages / Q000473:pathology; D024862:Oxyphil Cells / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology*