Asymmetric induction on beta-boration of alpha,beta-unsaturated compounds: an inexpensive approach.
Transition metal complexes mediate beta-boration of alpha,beta-unsaturated carbonyl compounds highlighting the advantages of using inexpensive catalytic systems, (Cu, Ni), both in the catalytic activity and selectivity. The new C(beta)-B bond can be accomplished in a stereoselective manner by modifying the metal complex with chiral ligands. Alternative mechanistic studies support the enantioselectivity observed, and large-scale applications of this reaction are currently being developed.
Lillo
Vanesa
V
Universitat Rovira i Virgili, C/Marcel.lí Domingo s/n., 43005, Tarragona, Spain.
Bonet
Amadeu
A
Fernández
Elena
E