Perspectives of data analysis of enzyme inhibition and activation, Part 1: Use of the three-dimensional K'm V'I coordinate system for data analysis of enzyme inhibition and activation.
The possibility of construction of the three-dimensional (unfolded and folded) K'm V'I rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a two-dimensional K'm V' scalar rectangular coordinate system convenient for diagrammatic representation of enzymatic reactions is considered. The perspectives of using the properties of the three-dimensional L vectors and their scalar L projections for data analysis of enzyme inhibition and activation are analyzed.
Krupyanko
Vladimir I
VI
G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Russia. krupyanko@ibpm.pushchino.ru
D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004798:Enzymes / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism*; D011487:Protein Conformation
D004791:Enzyme Inhibitors; D004798:Enzymes