[ARDS--pulmonary repair and therapeutic options].
The acute respiratory distress syndrome (ARDS) is characterized by inflammation evoked pulmonary edema, hyaline membranes, diffuse endothelial and epithelial injury, and fibrosis. For survival to occur lung repair is required. This review explores recent advances in the field of fibroproliferation with emphasis on cellular and soluble factors, mechanisms involved in lung repair, and genetic factors which influence severity and survival in ARDS.
Sixt
Stephan Urs
SU
Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen der Universität Duisburg-Essen. anaesthesixt@gmx.de
Adamzik
Michael
M
Peters
Jürgen
J
D006801:Humans; D012128:Respiratory Distress Syndrome / Q000628:therapy*