MapView: visualization of short reads alignment on a desktop computer.
We introduce a new visual analytics tool named MapView to facilitate the representation of large-scale short reads alignment data and genetic variation analysis. MapView can handle hundreds of millions of short reads on a desktop computer with limited memory. It supports a compact alignment view for both single-end and paired end short reads, multiple navigation and zoom modes and multi-thread processing. Moreover, MapView offers automated genetic variation detection. MapView has been used in our lab and by over 10 research labs worldwide.


BACKGROUND
http://evolution.sysu.edu.cn/mapview/.


BACKGROUND
Supplementary data are available at http://evolution.sysu.edu.cn/mapview/MVF.pdf.
Bao
Hua
H
State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China. baohua100@hotmail.com
Guo
Hui
H
Wang
Jinwei
J
Zhou
Renchao
R
Lu
Xuemei
X
Shi
Suhua
S
D019295:Computational Biology / Q000379:methods; D003196:Computer Graphics; D020869:Gene Expression Profiling / Q000379:methods; D014644:Genetic Variation; D016415:Sequence Alignment / Q000379:methods*; D012984:Software