Interventional therapies, surgery, and interdisciplinary rehabilitation for low back pain: an evidence-based clinical practice guideline from the American Pain Society.
METHODS
Clinical practice guideline.


OBJECTIVE
To develop evidence-based recommendations on use of interventional diagnostic tests and therapies, surgeries, and interdisciplinary rehabilitation for low back pain of any duration, with or without leg pain.


BACKGROUND
Management of patients with persistent and disabling low back pain remains a clinical challenge. A number of interventional diagnostic tests and therapies and surgery are available and their use is increasing, but in some cases their utility remains uncertain or controversial. Interdisciplinary rehabilitation has also been proposed as a potentially effective noninvasive intervention for persistent and disabling low back pain.


METHODS
A multidisciplinary panel was convened by the American Pain Society. Its recommendations were based on a systematic review that focused on evidence from randomized controlled trials. Recommendations were graded using methods adapted from the US Preventive Services Task Force and the Grading of Recommendations, Assessment, Development, and Evaluation Working Group.


RESULTS
Investigators reviewed 3348 abstracts. A total of 161 randomized trials were deemed relevant to the recommendations in this guideline. The panel developed a total of 8 recommendations.


CONCLUSIONS
Recommendations on use of interventional diagnostic tests and therapies, surgery, and interdisciplinary rehabilitation are presented. Due to important trade-offs between potential benefits, harms, costs, and burdens of alternative therapies, shared decision-making is an important component of a number of the recommendations.
Chou
Roger
R
Department of Medicine, Oregon Evidence-based Practice Center, Oregon Health and Science University, Portland, OR, USA. chour@ohsu.edu
Loeser
John D
JD
Owens
Douglas K
DK
Rosenquist
Richard W
RW
Atlas
Steven J
SJ
Baisden
Jamie
J
Carragee
Eugene J
EJ
Grabois
Martin
M
Murphy
Donald R
DR
Resnick
Daniel K
DK
Stanos
Steven P
SP
Shaffer
William O
WO
Wall
Eric M
EM
D002985:Clinical Protocols / Q000592:standards; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D000529:Complementary Therapies / Q000592:standards; D003362:Cost-Benefit Analysis; D003661:Decision Support Techniques; D019317:Evidence-Based Medicine / Q000706:statistics & numerical data; D006801:Humans; D017116:Low Back Pain / Q000534:rehabilitation* / Q000601:surgery / Q000628:therapy*; D019635:Neurosurgical Procedures / Q000379:methods / Q000592:standards*; D010348:Patient Care Team / Q000592:standards*; D018570:Risk Assessment