Strange bedfellows expose ancient secrets of autophagy in immunity.
Autophagy has many roles in immunity, including the control of intracellular microbes by a cell-autonomous mechanism. In this issue of Immunity, Shelly et al. (2009) use VSV infection in Drosophila to show the role of autophagy genes in controlling viruses.
Deretic
Vojo
V
Department of Molecular Genetics & Microbiology, University of New Mexico Health Sciences Center, 915 Camino de Salud, NE, Albuquerque, NM 87131-001, USA. vderetic@salud.unm.edu
D000818:Animals; D001343:Autophagy / Q000276:immunology*; D006801:Humans; D007109:Immunity; D014777:Virus Diseases / Q000276:immunology*