Concise synthesis of tricyclic isoindolinones via one-pot cascade multicomponent sequences.
A series of enantiopure tricyclic isoindolinones has been successfully synthesized through a one-pot selective cascade process from furan derivatives. The synthesis is straightforward and gave good overall yields taking into account the concomitant formation of five C-C, C-O, and C-N bonds. The strategy was extended to the preparation of a thiazolidine analogue.
Medimagh
Raouf
R
Institut Lavoisier de Versailles (ILV) UMR CNRS 8180, Universite de Versailles-Saint-Quentin-en-Yvelines, 45 Avenue des Etats-Unis, 78 035 Versailles, Cedex, France.
Marque
Sylvain
S
Prim
Damien
D
Marrot
Jérôme
J
Chatti
Saber
S