Comparative effect of an essential oil mouthrinse on plaque, gingivitis and salivary Streptococcus mutans levels: a double blind randomized study.
An open, randomized, controlled study with two parallel treatment groups was done to evaluate the efficacy of a Lippia sidoides essential oil (EO) 1% mouthrinse compared with chlorhexidine 0.12% mouthrinse, applied two times daily for 1 week, in the treatment of dental plaque and gingivitis. Fifty-five patients were included in the study. The efficacy variables were the colony count of Streptococcus mutans from the stimulated saliva and periodontal indices on days 0, 7 and 30 after commencement of therapy. Twenty eight patients received chlorhexidine mouthrinse (Periogard((R))) and 27 Lippia sidoides essential oil mouthrinse (Cepakill((R))). The clinical and microbiological parameters were significantly reduced by both mouthrinses. No significant difference was seen between the two groups (p > 0.05). There was a significant reduction in the colony count of S. mutans in both groups (p < 0.05). Chlorhexidine treatment reduced more efficiently than L. sidoides, however, no statistical difference was seen, the efficacy of both groups was similar (p = 0.3). The results indicate that Chlorhexidine mouthrinse reduced plaque index, gingival bleeding and the number of CFU (colonies forming units) more efficiently than L. sidoides but did not reach statistical significance. This study demonstrated that Lippia sidoides EO mouthrinse is effective in reducing microbial plaque and gingival inflammation.
Botelho
Marco Antonio
MA
Laboratório de Quimica, Curso de Odontologia, Faculdades Nordeste - Fortaleza Ceará, Brazil. botelhoufc@gmail.com
dos Santos
Rinaldo Araujo
RA
Martins
Jose Galberto
JG
Carvalho
Cintia Oliveira
CO
Paz
Mabel Calina
MC
Azenha
Cláudio
C
Ruela
Ronaldo Sousa
RS
Queiroz
Dinalva Brito
DB
Ruela
Wagner Sousa
WS
Marinho
Gloria
G
Ruela
Francisca Isabel
FI
D000293:Adolescent; D000328:Adult; D002710:Chlorhexidine / Q000627:therapeutic use*; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000188:drug therapy*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D005260:Female; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D032411:Lippia / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D009822:Oils, Volatile / Q000627:therapeutic use*; D010512:Periodontal Index; D010938:Plant Oils / Q000627:therapeutic use; D013295:Streptococcus mutans / Q000187:drug effects*; D016896:Treatment Outcome; D055815:Young Adult
D009067:Mouthwashes; D009822:Oils, Volatile; D010938:Plant Oils; D002710:Chlorhexidine