Boswellic acids: a group of medicinally important compounds.
This review, containing over 276 references, covers the progress made in the chemistry and bioactivity of this important group of triterpenoids. Though initially known for their anti-inflammatory and anti-arthritic activities through a unique 5-LO inhibition mechanism, boswellic acids have recently attained significance due to their anti-cancer properties. The phytochemistry and chemical modifications, including mechanism of action, are discussed.
Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu Tawi, 180001, India.
Bhahwal Ali
BA
Shah
Ghulam Nabi
GN
Qazi
Subhash Chandra
SC
Taneja
D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001168:Arthritis / Q000188:drug therapy*; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D001688:Biological Products; D014315:Triterpenes; C054625:boswellic acid