[Chronic hepatitis C in children: natural history and prognosis].
Chronic hepatitis C has been described as a mild disease in children, but viremia persists up to adult life in more than 80% of cases, fibrosis is slowly progressing throughout adolescence and youth, and early appearance of end stage liver disease has been recently documented. These findings, and the efficacy of current therapeutic strategies in adults, support the potential benefits of early treatment in children with chronic hepatitis C.
Fondazione Lionello Forin Hepatos Onlus, Padova. flaviabortolotti@libero.it
Flavia
F
Bortolotti
D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission; D006801:Humans; D015994:Incidence; D007372:Interferons / Q000627:therapeutic use; D007558:Italy / Q000453:epidemiology; D015995:Prevalence; D011379:Prognosis; D012254:Ribavirin / Q000627:therapeutic use; D012307:Risk Factors; D016896:Treatment Outcome; D014766:Viremia / Q000453:epidemiology / Q000821:virology
D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons