[Human adjuvant disease which developed after silicone augumentation mammoplasty].
A 73-year-old woman was admitted to our hospital to evaluate mediastinal lymphadenopathy found on a chest CT scan. She had undergone mammoplasty with silicone augmentation 50 years previously and had the implants removed 5 years previously. Biopsied specimens of a mediastinal lymph node under video-assisted thoracic surgery (VATS) revealed multiple hyalinized non-caseating epithelioid cell granulomas and multinucleated giant cells and foamy macrophages containing some vacuoles. According to these clinicopathological findings, we diagnosed human adjuvant disease which developed after mammoplasty with silicone augmentation. In cases of mammoplasty, we should pay attention to the complication of chronic thoracic disorder as a human adjuvant disease.
Muramatsu
Yoko
Y
Department of Respiratory Medicine, Toho University School of Medicine.
Sugino
Keishi
K
Kikuchi
Naoshi
N
Sano
Go
G
Isobe
Kazutoshi
K
Takai
Yujiro
Y
Takagi
Keigo
K
Shibuya
Kazutoshi
K
Homma
Sakae
S
D000368:Aged; D019928:Breast Implantation / Q000009:adverse effects*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology; D008477:Mediastinal Diseases / Q000209:etiology; D012828:Silicones / Q000009:adverse effects*
D012828:Silicones