Gorhams disease: vanishing bone syndrome.
Gorhams disease, also known as massive osteolysis or vanishing bone disease is an extremely rare bone disease. It is characterized by angiomatosis with adjacent bone resorption. We report an 8-years old boy with the disease who was managed successfully with alpha 2b interferon therapy.
Prasanna
R
R
Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Nungambakkam, Chennai, India. dr_prasannaraju@yahoo.com
Sankar
Janani
J
Ramachandran
Priya
P
D002648:Child; D002916:Chylothorax / Q000209:etiology / Q000628:therapy; D004164:Diphosphonates / Q000627:therapeutic use; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D016898:Interferon-alpha; D008297:Male; D010014:Osteolysis; D010015:Osteolysis, Essential / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D011994:Recombinant Proteins
D004164:Diphosphonates; D007370:Interferon Type I; D016898:Interferon-alpha; D011994:Recombinant Proteins; C076799:interferon-alpha 8