[Current requirements for polymeric biomaterials in ear, nose and throat medicine].
In recent years the ear, nose and throat medicine (ENT medicine) has been stimulated by numerous innovations in the field of implants which are based on new biomaterials and modern implant technologies. In this context, biomaterials integrated in living organisms have to allow for the technical requirements and the biological interactions between the implant and the tissue. With regard to their suitability, functional capability of the implant, which is complementary to the mechanical implant properties, sufficient stability against physiological media, as well as high biocompatibility are to be demanded. Another purpose of the use of biomaterials is the maintenance and the enhancement of biofunctionality over a long time period. These general requirements for biomaterials also have their validity in ENT medicine. Different materials are applied as biomaterials. Metals belong to the oldest biomaterials. In addition, alloys, ceramics, inorganic glasses and composites were tested. Furthermore, natural and synthetic polymers, which are primarily presented in this article regarding their properties and their applications as materials for cochlear implants, osteosynthesis implants, stents and novel scaffolds for tissue engineering, are increasingly applied. According to their use in permanent and temporary implants, polymers are to be differentiated between biostable and biodegradable polymers. The presented general and current requirements for biomaterials and biomaterial applications in ENT medicine demonstrate key aspects of the current biomaterial research in this field. They do as well document the high impact of the interdisciplinary collaboration of natural and medical scientists and engineers.
Universität Rostock, Institut für Biomedizinische Technik, Rostockkatrin.sternberg@uni-rostock.de
K
K
Sternberg
D020341:Absorbable Implants; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D003054:Cochlear Implants; D003907:Dexamethasone / Q000008:administration & dosage; D054855:Drug-Eluting Stents; D006801:Humans; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010036:Otolaryngology / Q000295:instrumentation*; D011108:Polymers; D019736:Prostheses and Implants; D011474:Prosthesis Design; D012106:Research; D013499:Surface Properties; D023822:Tissue Engineering
D000893:Anti-Inflammatory Agents; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D011108:Polymers; D003907:Dexamethasone