Inhibition of infectious diseases by components from Aloe vera.
The ability to eliminate Escherichia coli K-12 from the peritoneal cavity in the early stage of infection (48 h) was improved by the pre-administration of an aloe sample to BALB/c mice. Our results suggest that the aloe sample could inhibit infectious diseases by stimulating the host defense mechanism, especially the phagocytic and killing activities of macrophages.
Tamura
Norimitsu
N
Division of Agriscience and Bioscience, Institute of Symbiotic Science and Technology, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Yoshida
Tadashi
T
Miyaji
Kazuhiro
K
Sugita-Konishi
Yoshiko
Y
Hattori
Makoto
M
D000504:Aloe / Q000737:chemistry*; D000818:Animals; D001424:Bacterial Infections / Q000276:immunology / Q000378:metabolism / Q000517:prevention & control*; D004927:Escherichia coli Infections / Q000276:immunology / Q000378:metabolism / Q000517:prevention & control; D048168:Escherichia coli K12 / Q000187:drug effects; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009569:Nitric Oxide / Q000096:biosynthesis; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D012995:Solubility
D010936:Plant Extracts; D009569:Nitric Oxide