[Ultrasound-guided renal intracapsular injection of methylprednisolone for primary glomerulonephritis].
OBJECTIVE
To evaluate ultrasound-guided renal intracapsular injection of methylprednisolone for primary glomerulonephritis.


METHODS
Thirty patients with primary glomerulonephritis were performed intra-renal adipose capsule injection therapy under ultrasound guidance. The 24 hour urinary protein, plasma total protein, plasma albumin, urine volume, and serum creatinine were measured before and after the treatment.


RESULTS
The injection success rate was 96.3% (314/326) in patients whose width of perinephric adipose capsule was >or= 5 mm. The injection success rate was 77.4% (212/274) in patients whose width of perinephric adipose capsule was < 5 mm (P < 0.01). The complications included pain, perirenal hematoma, and so on. The 24 hour urinary protein after the treatment was lower than before the treatment (P < 0.05). The plasma total protein and plasma albumin were higher than before the treatment (P < 0.05). The urine volume and serum creatinine were unchanged (P > 0.05).


CONCLUSIONS
Intra-renal adipose capsule injection under ultrasound guidance has a high success rate and good effect, and is effective to treat primary glomerulonephritis with glucocorticoid.
Department of Ultrasound, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Lin
L
Hu
Ping
P
Zhou
Peng
P
Zhou
Shuangming
S
Tian
Xinghua
X
Li
Lihua
L
Wang
Hao
H
Zhang
D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy*; D006801:Humans; D007267:Injections / Q000379:methods*; D007668:Kidney / Q000187:drug effects*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D018084:Ultrasonography, Interventional / Q000379:methods*; D055815:Young Adult
D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone