Plant peptides in signalling: looking for new partners.
A novel candidate ligand-receptor system, INFLORESCENCE DEFICIENT IN ABSCISSION (IDA) and the related receptor-like kinases (RLKs) HAESA (HAE) and HAESA-LIKE (HSL)2, has been shown to control floral abscission in Arabidopsis thaliana. Furthermore, several IDA-LIKE (IDL) proteins, which contain a conserved C-terminal domain resembling that of the CLAVATA (CLV)3-ENDOSPERM SURROUNDING REGION (ESR)-RELATED (CLE) protein family, have been shown to be partially redundant with IDA. Here, we use the genetic similarities between the IDA and CLV3 signalling systems to hypothesize that closely related peptide ligands are likely to interact with families of closely related RLKs. Guided by this hypothesis and with the aid of genetics and novel methods, ligand-receptor systems can be identified to improve our understanding of developmental processes in plants.
Butenko
Melinka A
MA
Department of Molecular Biosciences, University of Oslo, N-0316 Oslo, Norway.
Vie
Ane Kjersti
AK
Brembu
Tore
T
Aalen
Reidunn B
RB
Bones
Atle M
AM
D029681:Arabidopsis Proteins / Q000145:classification / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D018506:Gene Expression Regulation, Plant; D008954:Models, Biological; D010455:Peptides / Q000145:classification / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D010802:Phylogeny; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology*
C118167:AT2G27250 protein, Arabidopsis; D029681:Arabidopsis Proteins; C512213:IDA protein, Arabidopsis; D010455:Peptides; C089427:RLK5 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases