Long-term outcome of palliation with internal pulmonary artery bands after primary heart transplantation for hypoplastic left heart syndrome.
The purpose of this study was to describe the long-term outcome of infants with hypoplastic left heart syndrome (HLHS) who underwent placement of internal pulmonary artery bands as part of a transcatheter palliation procedure followed by primary heart transplantation. Transcatheter palliation included stenting of the ductus arteriosus, decompression of the left atrium by atrial septostomy, and internal pulmonary artery band placement. Cardiac hemodynamics, pulmonary artery architecture, and pulmonary artery growth since transplantation are described. Nine infants with HLHS had internal pulmonary artery bands placed and underwent successful heart transplant. No infant required reconstruction of the pulmonary arteries at the time of transplant. At 1 year after transplant, all of the recipients had normal mean pulmonary artery pressure, pulmonary vascular resistance, and transpulmonary gradient. Pulmonary angiography performed at 1 year after transplant demonstrated no distortion of pulmonary artery anatomy with significant interval growth of the branch pulmonary arteries. There was 100% survival to hospital discharge after transplant in this cohort of infants. Transcatheter placement of internal pulmonary artery bands for HLHS offers protection of the pulmonary vascular bed while preserving pulmonary artery architecture and growth with good long-term outcome.
Department of Pediatric Cardiology, University of Colorado Denver Health Sciences Center and The Children's Hospital, Aurora, CO 80045, USA. miyamoto.shelley@tchden.org
Shelley D
SD
Miyamoto
Biagio A
BA
Pietra
Kak-Chen
KC
Chan
David D
DD
Ivy
Christine
C
Mashburn
David N
DN
Campbell
Max B
MB
Mitchell
Mark M
MM
Boucek
D000800:Angioplasty, Balloon; D006328:Cardiac Catheterization; D005260:Female; D016027:Heart Transplantation; D006439:Hemodynamics; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000601:surgery* / Q000628:therapy; D007223:Infant; D008297:Male; D010166:Palliative Care; D011651:Pulmonary Artery / Q000601:surgery*; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome