Synthesis of supramolecular nanocapsules based on threading of multiple cyclodextrins over polymers on gold nanoparticles.
The CD's stuck: Poly(ethylene glycol) chains anchored onto gold nanoparticles (AuNPs) are threaded by multiple alpha-cyclodextrin (alpha-CD) rings to form a supramolecular outer layer composed of pseudopolyrotaxane columns perpendicular to the nanoparticle surface. Capping the polymer ends confines alpha-CD on the nanoparticle surface, cross-linking the alpha-CD rings and then removing the AuNP cores produces supramolecular nanocapsules.
Wu
Yun-Long
YL
Division of Bioengineering, Faculty of Engineering, National University of Singapore, 7 Engineering Drive 1, Singapore 117574, Singapore.
Li
Jun
J
D003432:Cross-Linking Reagents / Q000737:chemistry; D003505:Cyclodextrins / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D018625:Microscopy, Atomic Force; D008958:Models, Molecular; D015394:Molecular Structure; D053769:Nanocapsules / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013053:Spectrophotometry
D003432:Cross-Linking Reagents; D003505:Cyclodextrins; D053769:Nanocapsules; D011108:Polymers; D006046:Gold