Coherent activation of DNA tweezers: a "SET-RESET" logic system.
Open sesame: Aptamer-substrate complexes activate the coherent operation of two tweezers that act as a "SET-RESET" logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q = quencher, F = fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).
The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
Johann
J
Elbaz
Michal
M
Moshe
Itamar
I
Willner
D000243:Adenosine Deaminase / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000737:chemistry / Q000378:metabolism; D052157:Aptamers, Nucleotide / Q000737:chemistry / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D008128:Logic; D009690:Nucleic Acid Conformation
D052157:Aptamers, Nucleotide; D000249:Adenosine Monophosphate; D004247:DNA; D000243:Adenosine Deaminase