Proliferative vitreoretinopathy: pathobiology and therapeutic targets.
The cell biology and molecular mediators of proliferative vitreoretinopathy continue to be elucidated. The purpose of this review is to summarize contemporary findings in the visual and neurosciences relevant to the pathophysiology of proliferative vitreoretinopathy, with an emphasis on the biologic mediators that represent potential therapeutic targets.
Retina Service, The Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA. Yannek Leiderman@meei.harvard.edu
Yannek I
YI
Leiderman
Joan W
JW
Miller
D000818:Animals; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism; D012163:Retinal Detachment / Q000209:etiology; D018630:Vitreoretinopathy, Proliferative / Q000150:complications / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*
D036341:Intercellular Signaling Peptides and Proteins