[Cold injury as a cause of stable changes in microcirculation].
Using laser Doppler flowmetry comparative evaluation of microcirculatory condition and regulatory components of vascular tone in lower limbs was carried out in 40 patients with local cold injuries in late reactive period and 12 reconvalescents with trophic disturbances. Microcirculation index decreased in all patients while neurogenous and myogenous vascular tone increased. Peak oscillation amplitude decreased in the endothelial range. At the same time in reconvalescents changes in passive regulatory components of vascular tone increase and frequency of peak amplitude neurogenous variation decrease. Thus, cold impact results in stable changes of microcirculation and therefore in dysthrophic changes in affected tissues.
K G
KG
Shapovalov
V A
VA
Sizonenko
D000293:Adolescent; D000328:Adult; D003289:Convalescence; D003627:Data Interpretation, Statistical; D005627:Frostbite / Q000503:physiopathology*; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007866:Leg / Q000098:blood supply*; D008833:Microcirculation; D008875:Middle Aged