Expression of rat sperm flagellum-movement associated protein genes under 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment.
We analyzed the gene expression of sperm flagellum-movement associated proteins, namely, adenylate kinase domain containing protein (RGD1303144) and outer dense fiber protein 1. These gene expressions were up-regulated in a maturing rat testis, and RGD1303144 gene was expressed dominantly in spermatocytes. Although 2,3,7,8-tetrachlorodibenzo-p-dioxin administration reduced sperm motility, these gene expressions were not affected.
Laboratory of Veterinary Biochemistry, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan. yyamano@muses.tottori-u.ac.jp
Yoshiaki
Y
Yamano
Atsushi
A
Asano
Masanori
M
Ohta
Shuji
S
Hirata
Tomoko
T
Shoda
Kenji
K
Ohyama
D000263:Adenylate Kinase / Q000378:metabolism; D000818:Animals; D015152:Blotting, Northern; D052244:Endocrine Disruptors / Q000633:toxicity*; D005786:Gene Expression Regulation / Q000187:drug effects*; D006360:Heat-Shock Proteins / Q000235:genetics; D008297:Male; D009068:Movement; D000072317:Polychlorinated Dibenzodioxins / Q000633:toxicity*; D017434:Protein Structure, Tertiary; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D013082:Sperm Tail / Q000378:metabolism*; D013090:Spermatocytes / Q000187:drug effects / Q000378:metabolism
D052244:Endocrine Disruptors; D006360:Heat-Shock Proteins; C490108:Odf1 protein, rat; D000072317:Polychlorinated Dibenzodioxins; D012333:RNA, Messenger; D000263:Adenylate Kinase