[Antioxidant and membranotropic action of monochromanes and trimethylphenols derivatives in vitro].
Using some biochemical and physico-chemical methods of investigation, antioxidant activity and membrane protective effect of derivatives of monochromanes and trimethylphenols has been studied most active inhibitors of lipoperoxidation and the compounds capacity to structural modification of properties of the surface and hydrophobic zones of phospholipids bilayer in membranes of endoplasmic reticulum of the liver cells of rats have been determined.
Hubs'kyĭ
Iu I
IuI
Horiushko
H H
HH
Litvinova
N V
NV
Makovets'kyĭ
V P
VP
Kurapova
T M
TM
Afanasenko
O V
OV
Velychko
O M
OM
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002839:Chromans / Q000737:chemistry / Q000494:pharmacology*; D004721:Endoplasmic Reticulum / Q000187:drug effects* / Q000378:metabolism; D066298:In Vitro Techniques; D007425:Intracellular Membranes / Q000187:drug effects* / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000166:cytology / Q000187:drug effects; D008297:Male; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship
D000975:Antioxidants; D002839:Chromans; D010636:Phenols; D010743:Phospholipids