[Can the thalamic projections of medulla oblongata nucleus Z be reorganized following partial deafferentation of the ventral lateral thalamic nucleus?].
Following partial deafferentation of ventral lateral thalamic nucleus by means of HRP retrograde labeling, possible plastic reorganization of projections of the brain stem relay Z nucleus was studied in cats. The partial deafferentation of ventral lateral thalamic nucleus was evoked by preliminary (3 months before) destroying of contralateral cerebellar nucleus interpositus or Deiters' lateral vestibular nucleus. The local intensive labeling of neurons in the Z nucleus and a little group of neurons in the cellular group x of the vestibular complex projecting to ventral lateral thalamic nucleus and overlapping with those projecting from cerebellum was observed. It was shown that, following destruction of the cerebellar nucleus interpositus or Deiters' nucleus, the ipsilateral projections in the nucleus monosynaptic link are not forming. The absence of Z nucleus-ventral lateral thalamic nucleus projections reorganization similar to the formation ofipsilateral projections possibly depends on its belonging to the somatosensory relay nucleus which provides switching and transmission of specific proprioceptuve modality.
S A
SA
Badalian
V A
VA
Sargsian
Dzh S
DS
Sarkisian
D000818:Animals; D002415:Cats; D008526:Medulla Oblongata / Q000166:cytology / Q000502:physiology*; D020651:Ventral Thalamic Nuclei / Q000166:cytology / Q000502:physiology*; D003689:Vestibular Nucleus, Lateral / Q000166:cytology / Q000502:physiology*