In vitro activity of doripenem against Burkholderia pseudomallei.
The MIC(50) and MIC(90) values of doripenem, determined by Etest, for 110 isolates of Burkholderia pseudomallei were 0.5 and 0.75 microg/ml, respectively. There were significant correlations between MICs determined by Etest and MICs determined by agar dilution, MICs determined by Etest and inhibition zone size, and MICs determined by agar dilution and inhibition zone size.
Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. sivth@mahidol.ac.th
Visanu
V
Thamlikitkul
Suwanna
S
Trakulsomboon
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016957:Burkholderia pseudomallei / Q000187:drug effects*; D015780:Carbapenems / Q000494:pharmacology*; D000077726:Doripenem; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D015780:Carbapenems; D000077726:Doripenem