[Repeated intestinal tract perforations secondary to cryoglobulinemia and cytomegalovirus infection: a case report].
Cryoglobulinemia associated vasculitis is usually related to hepatitis C virus. Clinical features include purpura, glomerulonephritis, or peripheral neuropathy. Intestinal involvement in cryoglobulinemia is rare and has a poor prognosis. It often leads to a therapeutic with immunosupressive drugs. The related immunodepression exposes to a reactivation of cytomegalovirus (CMV) infection that may also be potentially responsible for intestinal injury. We report a 68-year-old man who presented with iterative intestinal perforations secondary to a cryoglobulinemia vasculitis and then to a CMV infection.
Service de médecine interne A, hôpital Saint-Eloi, CHU de Montpellier, avenue Augustin-Flisches, 34000 Montpellier, France. p-befort@chu-montpellier.fr <p-befort@chu-montpellier.fr>
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D000368:Aged; D003449:Cryoglobulinemia / Q000150:complications* / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology; D008297:Male; D010538:Peritonitis / Q000209:etiology; D011379:Prognosis