Ultra-small water-dispersible fluorescent chitosan nanoparticles: synthesis, characterization and specific targeting.
A robust water-in-oil microemulsion method of making water-dispersible ultra-small (<30 nm) size fluorescent chitosan nanoparticles is reported for the first time and specific targeting of these FCNPs to human leukemia cells via aptamer recognition is demonstrated.
Tallury
Padmavathy
P
NanoScience Technology Center, University of Central Florida, Orlando, FL 32826, USA.
Kar
Soumitra
S
Bamrungsap
Suwussa
S
Huang
Yu-Fen
YF
Tan
Weihong
W
Santra
Swadeshmukul
S
D045744:Cell Line, Tumor; D048271:Chitosan / Q000138:chemical synthesis* / Q000737:chemistry; D005434:Flow Cytometry; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D014867:Water / Q000737:chemistry*
D005456:Fluorescent Dyes; D014867:Water; D048271:Chitosan