[Severe infectious keratitis in renal transplant patient: a case report].
Keratitis occurring in renal transplant patients are often severe, with difficult management. We describe the case of a renal transplant patient, 44 year-old man, with history of recurrent herpetic keratitis, which developed an impending corneal perforation. Conjunctival smear showed the presence of amoebic cysts. Anti-amoebic treatment was undertaken in addition with oral aciclovir, and a therapeutic penetrating keratoplasty was performed. An ulceration of the graft occurred within five months. Ocular samples showed the presence of Candida albicans. Despite aggressive antifungal therapy, he required a second therapeutic penetrating keratoplasty for graft perforation. One month later, we noted a recurrence of the ulcer with corneal thinning which evolved to perforation.
Service B, institut Hedi Rais d'ophtalmologie de Tunis, 4, impasse Tarek Ibn Zied, Mutuelleville, 1082 Tunis, Tunisie. rlimaiem@yahoo.fr
Rim
R
Limaiem
Heni
H
Mnasri
Abir
A
El Maazi
Hela
H
Ammari
Afif
A
Chaabouni
Fatma
F
Mghaieth
Leila
L
El Matri
D000212:Acyclovir / Q000627:therapeutic use*; D000328:Adult; D000562:Amebiasis / Q000175:diagnosis* / Q000188:drug therapy; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000302:isolation & purification; D003228:Conjunctiva / Q000469:parasitology / Q000473:pathology* / Q000601:surgery; D016039:Corneal Transplantation; D006801:Humans; D016849:Keratitis, Herpetic / Q000150:complications* / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D012008:Recurrence; D012167:Retinal Perforations / Q000209:etiology* / Q000382:microbiology / Q000469:parasitology / Q000601:surgery
D000935:Antifungal Agents; D000212:Acyclovir