Inflammatory components of adipose tissue as target for treatment of metabolic syndrome.
Obesity is an independent risk factor in the etiology of various metabolic diseases such as insulin resistance, type 2 diabetes and cardiovascular diseases. In this chapter, we discuss obesity-induced inflammation as a potential link with obesity-related metabolic syndrome, and discuss how obesity-related inflammatory components such as immune cells, and cytokines/chemokines and adipocy-tokines, provoke obesity-related pathologies. In particular, we focus on the hypothesis that anti-inflammatory food factors/phytochemicals may be useful for inhibiting the initiation and development of obesity-induced inflammation and metabolic syndrome.
Rina
R
Yu
Chu-Sook
CS
Kim
Ji-Hye
JH
Kang
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D002211:Capsaicin / Q000494:pharmacology; D004032:Diet / Q000379:methods; D006801:Humans; D007249:Inflammation / Q000150:complications* / Q000178:diet therapy / Q000378:metabolism; D024821:Metabolic Syndrome / Q000150:complications / Q000178:diet therapy* / Q000378:metabolism; D051379:Mice; D009765:Obesity / Q000150:complications* / Q000178:diet therapy / Q000378:metabolism; D017365:Spices
D002211:Capsaicin