[Genetic mechanisms of E. coli cell stability to the antibiotics].
Mycotoxin Fumonisin B1 posseesses the weak DNA-damage activity for the E. coli strain defective in UvrA gene participating in DNA reparation. Fumonisin B1 in the concentration 10(-5) M increases a resistance of wild type E. coli cells to antibiotic doxycycline. Obtained results indicate the influence of fumonisin B1 on the genome of the cultured E. coli cells.
O B
OB
Ivanchenko
E A
EA
Martynova
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004249:DNA Damage; D004260:DNA Repair; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D037341:Fumonisins / Q000494:pharmacology*; D005798:Genes, Bacterial; D009154:Mutation
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D037341:Fumonisins; C056933:fumonisin B1