The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Mucositis: from febrile neutropenia to febrile mucositis.
The treatment of patients with cancer is often accompanied by life-threatening complications caused by chemotherapy and radiotherapy. They are known to result from neutropenia, but damage to the mucosal barrier as well as the humoral and cellular immune defences play a significant role in various infectious complications and aggravate diverse inflammatory processes. The article describes the journey from febrile neutropenia to febrile mucositis in patients treated with immunocompromising therapy.
Department of Haematology, Radboud University Medical Center, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands. N.Blijlevens@hemat.umcn.nl
Nicole M A
NM
Blijlevens
Richard M
RM
Logan
Mihai G
MG
Netea
D019090:Case Management; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D052016:Mucositis / Q000175:diagnosis* / Q000628:therapy*; D009503:Neutropenia / Q000150:complications*
D007166:Immunosuppressive Agents