Database of queryable gene expression patterns for Xenopus.
The precise localization of gene expression within the developing embryo, and how it changes over time, is one of the most important sources of information for elucidating gene function. As a searchable resource, this information has up until now been largely inaccessible to the Xenopus community. Here, we present a new database of Xenopus gene expression patterns, queryable by specific location or region in the embryo. Pattern matching can be driven either from an existing in situ image, or from a user-defined pattern based on development stage schematic diagrams. The data are derived from the work of a group of 21 Xenopus researchers over a period of 4 days. We used a novel, rapid manual annotation tool, XenMARK, which exploits the ability of the human brain to make the necessary distortions in transferring data from the in situ images to the standard schematic geometry. Developmental Dynamics 238:1379-1388, 2009. (c) 2009 Wiley-Liss, Inc.
Gilchrist
Michael J
MJ
Gurdon Institute, Cambridge University, Cambridge, United Kingdom. m.gilchrist@gurdon.cam.ac.uk
Christensen
Mikkel B
MB
Bronchain
Odile
O
Brunet
Frédéric
F
Chesneau
Albert
A
Fenger
Ursula
U
Geach
Timothy J
TJ
Ironfield
Holly V
HV
Kaya
Ferdinand
F
Kricha
Sadia
S
Lea
Robert
R
Massé
Karine
K
Néant
Isabelle
I
Paillard
Elodie
E
Parain
Karine
K
Perron
Muriel
M
Sinzelle
Ludivine
L
Souopgui
Jacob
J
Thuret
Raphaël
R
Ymlahi-Ouazzani
Qods
Q
Pollet
Nicolas
N
D000818:Animals; D030541:Databases, Genetic; D015870:Gene Expression; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D012984:Software; D014982:Xenopus laevis / Q000033:anatomy & histology / Q000196:embryology* / Q000235:genetics*