[Biomaterials in cochlear implants].
Cochlear implants (CI) represent the "gold standard" for the treatment of congenitally deaf children and postlingually deafened adults. Thus, cochlear implantation is a success story of new bionic prosthesis development. Owing to routine application of cochlear implants in adults but also in very young children (below the age of one), high demands are placed on the implants. This is especially true for biocompatibility aspects of surface materials of implant parts which are in contact with the human body. In addition, there are various mechanical requirements which certain components of the implants must fulfil, such as flexibility of the electrode array and mechanical resistance of the implant housing. Due to the close contact of the implant to the middle ear mucosa and because the electrode array is positioned in the perilymphatic space via cochleostomy, there is a potential risk of bacterial transferral along the electrode array into the cochlea. Various requirements that have to be fulfilled by cochlear implants, such as biocompatibility, electrode micromechanics, and although a very high level of technical standards has been carried out there is still demand for the improvement of implants as well as of the materials used for manufacturing, ultimately leading to increased implant performance. General considerations of material aspects related to cochlear implants as well as potential future perspectives of implant development will be discussed.
Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Medizinische Hochschule Hannover, Hannover. stoever.timo@mh-hannover.de
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D000328:Adult; D000818:Animals; D001424:Bacterial Infections / Q000517:prevention & control; D001672:Biocompatible Materials; D018441:Biofilms; D002648:Child; D002675:Child, Preschool; D020099:Coated Materials, Biocompatible; D003051:Cochlea / Q000382:microbiology / Q000601:surgery; D003054:Cochlear Implants / Q000382:microbiology / Q000592:standards; D003638:Deafness / Q000534:rehabilitation*; D004567:Electrodes, Implanted / Q000382:microbiology / Q000592:standards; D019544:Equipment Failure Analysis; D005549:Foreign-Body Reaction / Q000517:prevention & control; D006801:Humans; D007223:Infant; D053758:Nanoparticles; D011474:Prosthesis Design; D017755:Prosthesis Fitting; D016459:Prosthesis-Related Infections / Q000517:prevention & control; D012015:Reference Standards; D012086:Reoperation; D013499:Surface Properties
D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible