[Cytogenetic examination of nuclear specialists exposed to chronic beta-radiation of tritium].
For the first time the cytogenetic examination of the group of nuclear specialists (79 persons) chronically exposed to tritium beta-radiation for a long period was carried out. The frequencies of unstable (conventional method) and stable (FISH-method) chromosome aberrations have been analyzed. 50 years after the beginning of working under the conditions of the increased radiation level the differences (in comparison with control values) were revealed for all cytogenetic parameters. The frequency of the radiation-specific markers (dicentrics and centric rings) exceeds more than 2-fold the control level. A significant but poor correlation between the frequency of unstable aberrations and the total absorbed dose (during the whole working period) was revealed. A retrospective estimation of irradiation doses for 14 nuclear workers was made by the frequency of stable chromosome aberrations. The obtained dose values ranged from 110 to 1250 mSv.
Snigireva
G P
GP
Khaĭmovich
T I
TI
Bogomazova
A N
AN
Gorbunova
I N
IN
Nagiba
V I
VI
Nikanorova
E A
EA
Novitskaia
N N
NN
Khazins
E D
ED
D000368:Aged; D001610:Beta Particles / Q000009:adverse effects*; D002869:Chromosome Aberrations; D020732:Cytogenetic Analysis; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D016273:Occupational Exposure; D014316:Tritium / Q000009:adverse effects*; D014916:Whole-Body Irradiation
D014316:Tritium