Therapeutic drug monitoring of clozapine in a hemodialysed smoking patient with schizophrenia.
We describe a 38-year-old smoking woman suffering from schizophrenia, hemodialysed 3 times a week, and treated with clozapine. Therapeutic drug monitoring of clozapine was performed to guide therapy.
Service de Pharmacologie, AP-HP, Hôpital Pitié-Salpêtrière, 75651 Paris Cedex 13, France.
Aude
A
Jacob
Noël
N
Zahr
Jean-Sébastien
JS
Hulot
Samia
S
Boussouar
Jeanne
J
Vilain
Stéphanie
S
Lafont-Rapnouil
Franck
F
Schurhoff
Christian
C
Funck-Brentano
D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D003024:Clozapine / Q000493:pharmacokinetics* / Q000627:therapeutic use; D004347:Drug Interactions; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D006435:Renal Dialysis; D012559:Schizophrenia / Q000188:drug therapy / Q000378:metabolism*; D012907:Smoking / Q000378:metabolism* / Q000628:therapy
D003024:Clozapine