F-18 FDG PET-CT findings in Mikulicz disease and systemic involvement of IgG4-related lesions.
A 72-year-old woman with Mikulicz disease with pathogically proven sclerosing sialadenitis showed systemic abnormal F-18 FDG uptake in the bilateral lacrimal and submandibular glands, pancreas, abdominal aortic wall, and a retroperitoneal fibroid mass on PET/CT scan, with marked elevation of the serum IgG4 level. This case supports Mikulicz disease being included as 1 of the disorders associated with a new clinical entity of systemic IgG4-related plasmacytic syndrome. A whole-body FDG-PET/CT scan can be expected as a useful tool for detecting systemic involvement in systemic IgG4-related plasmacytic syndrome.
Department of Radiology, St. Hill Hospital, Ube, Yamaguchi, Japan. sugar@sthill-hp.or.jp
Kazuyoshi
K
Suga
Yasuhiko
Y
Kawakami
Atsuto
A
Hiyama
Kenji
K
Hori
Megumi
M
Takeuchi
D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008882:Mikulicz' Disease / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology; D010950:Plasma Cells / Q000000981:diagnostic imaging / Q000473:pathology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D007074:Immunoglobulin G; D019788:Fluorodeoxyglucose F18