[Structured treatment interruption in HIV-infected adolescents].
Structured treatment interruption in HIV is now being debated. There are 2 cases in which it may be discussed: when the initial treatment was started early and when there is no compliance to treatment [Yeni P, et al. Les nouvelles recommandations de prise en charge des personnes infectées par le VIH 2006. Paris: Flammarion médecine-sciences; 2006]. Noncompliant behavior is one of the characteristics of chronic illness during adolescence. In HIV infection, however, the prognosis is negatively influenced because the resulting resistance to the antiretroviral therapy can further reduce therapeutic options. Therefore, it is important in such a critical period to consider both what is consciously and unconsciously at stake and what responsible action could be taken when a specialist is faced with spontaneous (unplanned) treatment interruption. We report here examples of follow-up care, interruption, and resumption of treatment in 4 female adolescents.
Service de consultation de pédiatrie infectieuse-pédiatrie III, hôpital Arnaud-de-Villeneuve, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex 05, France. p-vidal@chu-montpellier.fr
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D000293:Adolescent; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D024921:Drug Resistance, Multiple, Viral; D005260:Female; D005500:Follow-Up Studies; D005602:France; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology / Q000635:transmission; D006801:Humans; D008297:Male; D010348:Patient Care Team; D010349:Patient Compliance / Q000523:psychology; D011379:Prognosis; D012017:Referral and Consultation; D019562:Viral Load
D019380:Anti-HIV Agents