Argon laser peripheral iridoplasty for topiramate-induced bilateral acute angle closure.
OBJECTIVE
To report a case of a topiramate-induced bilateral acute angle closure that was treated successfully by argon laser peripheral iridoplasty (ALPI).


METHODS
A 59-year-old healthy woman taking oral topiramate developed bilateral acute angle closure. B-scan ultrasonography, ultrasound biomicroscopy, and slit-lamp adapted ocular coherence tomography were performed.


RESULTS
The patient had shallow anterior chambers and total angle closure for 360 degrees OU. Ocular imaging showed circumferential ciliochoroidal effusions with anterior displacement of the iris-lens diaphragm. ALPI relieved the angle closure.


CONCLUSIONS
ALPI should be considered as initial therapy for topiramate-induced acute angle closure.
Sbeity
Zaher
Z
Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, NY, USA.
Gvozdyuk
Nadezhda
N
Amde
Wendewessen
W
Liebmann
Jeffrey M
JM
Ritch
Robert
R
D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D007839:Functional Laterality; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D032801:Iridectomy / Q000379:methods*; D007498:Iris / Q000473:pathology / Q000601:surgery*; D053685:Laser Therapy; D054018:Lasers, Excimer / Q000627:therapeutic use*; D033401:Microscopy, Acoustic; D008875:Middle Aged; D041623:Tomography, Optical Coherence; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose