Addison's disease with pituitary hyperplasia: a case report and review of the literature.
This case study describes a 33-year-old man with Addison's disease who presented with increased plasma adrenocorticotropic hormone (ACTH), normal plasma cortisol, and absent diurnal rhythms. Magnetic resonance imaging (MRI) indicated pituitary hyperplasia. Conventional hydrocortisone replacement therapy may not inhibit high ACTH levels in the morning; however, replacing hydrocortisone with dexamethasone achieved good therapeutic results.
Zhou
Jiaqiang
J
Department of Endocrinology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, People's Republic of China. zhoujq27@yahoo.com
Ruan
Lingxiang
L
Li
Hong
H
Wang
Qingqing
Q
Zheng
Fenping
F
Wu
Fang
F
D000224:Addison Disease / Q000150:complications* / Q000000981:diagnostic imaging; D000328:Adult; D006801:Humans; D006965:Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging; D008297:Male; D010900:Pituitary Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D010902:Pituitary Gland / Q000473:pathology*; D011859:Radiography