A new chalcone from Pongamia pinnata and its antioxidant properties.
The root bark of Pongamia pinnata Pierre [syn P. glabra (family: Fabaceae)] afforded a new chalcone (karanjapin) and two known flavonoids, a pyranoflavonoid (karanjachromene) and a furanoflavonoid (karanjin) The structure of karanjapin has been established from extensive 2D NMR spectral studies as beta,2'-dihydroxy-a,4'-dimethoxy-3,4-methylenedioxychalcone. Karanjapin and karanjachromene were found to possess significant antioxidant activity. This may play an important role in the pathogenesis of several diseases.
Ghosh
Anindita
A
Centre of Advanced Studies on Natural Products including Organic Synthesis, Department of Chemistry, Calcutta University, 92 A.P.C. Road, Kolkata-700 009, India.
Mandal
Suvra
S
Banerji
Avijit
A
Kar
Manoj
M
Banerji
Julie
J
D000975:Antioxidants / Q000737:chemistry*; D047188:Chalcones / Q000737:chemistry*; D033641:Millettia / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry
D000975:Antioxidants; D047188:Chalcones; C541193:karanjapin