Applications of 2D IR spectroscopy to peptides, proteins, and hydrogen-bond dynamics.
Following a survey of 2D IR principles, this article describes recent experiments on the hydrogen-bond dynamics of small ions, amide-I modes, nitrile probes, peptides, reverse transcriptase inhibitors, and amyloid fibrils.
Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA.
Yung Sam
YS
Kim
Robin M
RM
Hochstrasser
D000577:Amides / Q000737:chemistry*; D000682:Amyloid / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry*; D013055:Spectrophotometry, Infrared / Q000379:methods; D013816:Thermodynamics
D000577:Amides; D000682:Amyloid; D009570:Nitriles; D010455:Peptides; D018894:Reverse Transcriptase Inhibitors