Apnea-hypopnea index in nonobese women with polycystic ovary syndrome.
OBJECTIVE
To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women.


METHODS
Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7+/-0.57, age 29.1+/-1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9+/-0.58, age 31.6+/-3.87 years).


RESULTS
The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHI(NREM)) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHI(REM). Total testosterone level was positively correlated with AHI(NREM), and androstenedione was negatively correlated with AHI(NREM).


CONCLUSIONS
PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.
School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Hsiao-Ping
HP
Yang
Jiunn-Horng
JH
Kang
Hsiu-Yueh
HY
Su
Chii-Ruey
CR
Tzeng
Wei-Min
WM
Liu
Shih-Yi
SY
Huang
D000293:Adolescent; D000328:Adult; D000735:Androstenedione / Q000097:blood; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000209:etiology*; D012894:Sleep Stages; D012895:Sleep, REM; D013624:Taiwan; D013739:Testosterone / Q000097:blood; D055815:Young Adult
D013739:Testosterone; D000735:Androstenedione; D002097:C-Reactive Protein