Synthesis of 2-fluoroalkylbenzimidazoles via copper(I)-catalyzed tandem reactions.
Preparation of 2-fluoroalkylbenzimidazoles from N-aryl trifluoroacetimidoyl (or bromodifluoroacetimidoyl) chlorides and primary amines has been achieved via copper(I)-catalyzed tandem reactions.
Zhu
Jiangtao
J
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 LingLing Road, Shanghai 200032, PR China.
Xie
Haibo
H
Chen
Zixian
Z
Li
Shan
S
Wu
Yongming
Y
D000478:Alkylation; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D017611:Fluorine Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D012825:Silicon / Q000737:chemistry; D012997:Solvents
D001562:Benzimidazoles; D017611:Fluorine Compounds; D007477:Ions; D012997:Solvents; D003300:Copper; D012825:Silicon