Conversion of a neonatal hepatic hemangioma to focal nodular hyperplasia.
Hepatic hemangioma and focal nodular hyperplasia are both frequently observed benign lesions of the liver. Whereas hepatic hemangioma is the most frequent benign liver tumor in children, focal nodular hyperplasia occurs predominantly in adult patients. Concomitance of both entities has been described in adults, suggesting a similar pathogenesis. We report on a 6-month-old child with a continuously shrinking hepatic hemangioma after interventional therapy and a growing hepatic mass 5 years later, which emerged as focal nodular hyperplasia at the site of the former hemangioma. Diagnostic and therapeutic strategies regarding this patient are discussed. The present case supports the theory that these two entities may share a similar pathomechanism.
Department of Pediatric Surgery, Hannover Medical school, Hannover, Germany. turowski.carmen@mh-hannover.de
Carmen
C
Turowski
Henning
H
Feist
Gerhard
G
Alzen
Sylvia
S
Glüer
Claus
C
Petersen
D000792:Angiography; D002675:Child, Preschool; D004621:Embolization, Therapeutic; D020518:Focal Nodular Hyperplasia / Q000473:pathology* / Q000601:surgery; D006391:Hemangioma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D018615:Ultrasonography, Doppler, Color