Evaluation of sympathetic response in cases with failed back surgery syndrome.
OBJECTIVE
The aim of this study was to investigate whether sympathetic skin response (SSR) was affected in cases with failed back surgery syndrome (FBSS).


METHODS
Twenty-nine cases admitted to our department and diagnosed as FBSS were recruited for the study. All the cases had back, leg or back and leg pain in the months or in one year following spinal surgery. The control group consisted of 13 healthy hospital personnel. Electrophysiologic nerve conduction studies and SSR recordings were applied on the symptomatic side (29 legs) in study cases and both sides (26 legs) in the control group. SSRs of the study group were compared with those of the sex-, body mass index- and age-matched control group of 13 people. Patients having peripheral nerve entrapment syndromes, peripheral vascular disease, neurologic or psychiatric disease, alcoholism, or drug abuse were excluded from the study. Pain intensity was recorded by visual analog scale (VAS) and depression was recorded by Beck Depression Inventory (BDI).


RESULTS
Latency duration in SSR in the study group was significantly higher (p=0.006) when compared with the healthy controls. There was no SSR in 4 patients and there was a positive correlation between BDI and SSR (r=0.46).


CONCLUSIONS
It was concluded that the sympathetic nervous system is affected in FBSS patients with changes in SSR, and that the dysfunction of the sympathetic nervous system may contribute to the intensity and chronicity of pain states in this group of patients.
Department of Physical Medicine and Rehabilitation, Selçuk University, Meram Faculty of Medicine, Konya, Turkey. nilaysahin@gmail.com
Nilay
N
Sahin
Lütfiye
L
Müslümanoğlu
Omer
O
Karataş
Ayşegül
A
Cakmak
Emel
E
Ozcan
Ender
E
Berker
D000328:Adult; D016022:Case-Control Studies; D055111:Failed Back Surgery Syndrome / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D012867:Skin / Q000294:innervation* / Q000503:physiopathology; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D055815:Young Adult