[Human adjuvant disease which developed after silicone augumentation mammoplasty].
A 73-year-old woman was admitted to our hospital to evaluate mediastinal lymphadenopathy found on a chest CT scan. She had undergone mammoplasty with silicone augmentation 50 years previously and had the implants removed 5 years previously. Biopsied specimens of a mediastinal lymph node under video-assisted thoracic surgery (VATS) revealed multiple hyalinized non-caseating epithelioid cell granulomas and multinucleated giant cells and foamy macrophages containing some vacuoles. According to these clinicopathological findings, we diagnosed human adjuvant disease which developed after mammoplasty with silicone augmentation. In cases of mammoplasty, we should pay attention to the complication of chronic thoracic disorder as a human adjuvant disease.
Department of Respiratory Medicine, Toho University School of Medicine.
Yoko
Y
Muramatsu
Keishi
K
Sugino
Naoshi
N
Kikuchi
Go
G
Sano
Kazutoshi
K
Isobe
Yujiro
Y
Takai
Keigo
K
Takagi
Kazutoshi
K
Shibuya
Sakae
S
Homma
D000368:Aged; D019928:Breast Implantation / Q000009:adverse effects*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology; D008477:Mediastinal Diseases / Q000209:etiology; D012828:Silicones / Q000009:adverse effects*
D012828:Silicones