Gender as a moderator of cognitive and affective outcome after traumatic brain injury.
The aim of this investigation was to compare cognitive and affective functions in men and women who had suffered comparable brain injuries. In a prospective matched cohort design, 150 community-dwelling patients were individually matched on the basis of age, severity of injury, premorbid IQ, and time since injury. Women were significantly more impaired in verbal and visual memory compared with men. The degree of cognitive decline was significantly positively correlated with age in women, but not in men. Women had marginally higher scores compared with men on measures of anxiety and depression. It is concluded that gender is a moderator of cognitive and affective outcome after brain injury.
School of Psychology, University of Southampton, Highfield, Southampton, UK. cliossi@soton.ac.uk
Christina
C
Liossi
Rodger Ll
RL
Wood
D000328:Adult; D000367:Age Factors; D001007:Anxiety / Q000209:etiology; D001930:Brain Injuries / Q000150:complications* / Q000628:therapy*; D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology*; D015331:Cohort Studies; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008569:Memory Disorders / Q000209:etiology*; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011446:Prospective Studies; D012737:Sex Factors; D016896:Treatment Outcome; D055815:Young Adult