Synthesis of daldinol and nodulisporin A by oxidative dimerization of 8-methoxynaphthalen-1-ol.
The synthesis of two natural products, the para-para dimer of 8-methoxynaphthalen-1-ol (2), daldinol (3), and the related ortho-para dimer nodulisporin A (4) was achieved by the oxidation of 2 with ammonium metapervanadate (NH4VO3).
Department of Chemistry, University of Paderborn, Warburger Str. 100, 33098 Paderborn, Germany. k.krohn@uni-paderborn.de
Karsten
K
Krohn
Abdulselam
A
Aslan
D001203:Ascomycota / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry*
C541215:8-methoxynaphthalen-1-ol (2), daldinol; D009281:Naphthalenes; C541214:daldinol; C541213:nodulisporin A