Crotalidae polyvalent immune Fab for the treatment of pediatric crotaline envenomation.
Crotaline snakebites occur frequently in children, often resulting in significant morbidity. Crotalidae Polyvalent Immune Fab antivenom (FabAV) became available for clinical use in the US in 2000 and is currently the standard of care for the treatment of crotaline envenomation. The pediatric emergency care provider should be familiar with FabAV because its judicious use in affected children can greatly decrease morbidity caused by crotaline snakebites. This article will review the use of FabAV for the treatment of pediatric crotaline envenomation.
Division of Pediatric Emergency Medicine, Children's Medical Center of Dallas, Medical Toxicology, North Texas Poison Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA. collin.goto@childrens.com
Collin S
CS
Goto
Sing-Yi
SY
Feng
D000293:Adolescent; D000465:Algorithms; D000818:Animals; D000997:Antivenins / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D000075202:Contraindications; D003435:Crotalid Venoms / Q000633:toxicity; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D007128:Immunoglobulin Fragments / Q000009:adverse effects / Q000627:therapeutic use*; D012756:Sheep; D012909:Snake Bites / Q000453:epidemiology / Q000628:therapy*; D017819:Viperidae
D000997:Antivenins; D003435:Crotalid Venoms; C431183:Crotalidae Polyvalent immune Fab; D007140:Immunoglobulin Fab Fragments; D007128:Immunoglobulin Fragments