Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.
This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.
Cronan
John E
JE
Department of Biochemistry, University of Illinois, Urbana, Illinois, USA.
Thomas
Jacob
J
D001419:Bacteria / Q000235:genetics / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D005227:Fatty Acids / Q000096:biosynthesis*; D018942:Macrolides / Q000378:metabolism*; D008954:Models, Biological; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology
D001426:Bacterial Proteins; D005227:Fatty Acids; D018942:Macrolides