[Development of schizophrenia-spectrum psychoses caused by psychotraumatic events].
A study included 213 patients diagnosed with schizoaffective disorder (56.3%) or paranoid schizophrenia (43.7%). In all patients, psychotic symptoms developed under the influence of psychogenic factors. The high percentage of pathological personality disorders (50.2%), neurotic disorders (52.1%) and psychogenic depressive disturbances (53.5%) in the premorbid were found that indirectly indicates a liability to psychogenically caused endogenous psychoses. Three stages of development of schizophrenia-spectrum psychosis under the influence of psychogenic factors were singled out: psychogenic, endogenous-reactive (interim states) and endogenous psychotic disorders. Clinically heterogenic interim syndromes were specified as endogenous-reactive dysthymia (51.2%), obsessive-delusional syndrome (7.5%), hysteriform psychosis (20.2%) and endoreactive paranoia (21.2%). Psychotraumatic events caused three variants of schizophrenia-spectrum psychosis: affective, neurosis-like and paranoia. In conclusion, variants of the pathokinesis of psychogenically caused schizophrenia-spectrum psychosis predict the further course of endogenous process.
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Shmilovich
D005260:Female; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000145:classification / Q000209:etiology* / Q000503:physiopathology*; D012563:Schizophrenia, Paranoid / Q000145:classification / Q000209:etiology / Q000503:physiopathology; D040921:Stress Disorders, Traumatic / Q000150:complications*