Discovery and optimization of a TRAIL R2 agonist for cancer therapy.
Angell
Yvonne M
YM
Affymax, Inc., 4001 Miranda Avenue, Palo Alto, CA 94304, USA.
Bhandari
Ashok
A
De Francisco
M Nuria
MN
Frederick
Brian T
BT
Green
Jennifer M
JM
Leu
Karen
K
Leuther
Kerstin
K
Sana
Reuben
R
Schatz
Peter J
PJ
Whitehorn
Erik A
EA
Wright
Kathy
K
Holmes
Christopher P
CP
D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D055808:Drug Discovery; D006801:Humans; D013058:Mass Spectrometry; D018716:Molecular Mimicry; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000188:drug therapy*; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand / Q000819:agonists*
D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand