title: [Effects of Sarcandra glabra extract on immune activity in restraint stress mice].
abstract: OBJECTIVE
  To study the protective effect of Sarcandra glabra extract (SGE) on immune system in restrained mice.
  
  
  METHODS
  The male C57BL/6 mice were randomly divided into normal control group, stress control group, 125, 500 mg x kg(-1) SGE group. The spleen lymphocyte suspensions of each group were prepared. The parameters of spleen T cells subsets, NK cell and NKT cell proportion and number was detected by Flow cytometry.
  
  
  RESULTS
  SGE regulated the balance of T cell subsets, increased the percent of NK cells and NKT cell proportion and number in restrained mice.
  
  
  CONCLUSIONS
  SGE has immunologic protective effect in restrained mice probably via the amelioration of immune cells proportion and number.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. rongronghe66@163.com
authors.forename: Rongrong
authors.initials: R
authors.lastname: He
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Yifang
authors.initials: Y
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Dai
authors.forename: Yinghui
authors.initials: Y
authors.lastname: Duan
authors.forename: Xinsheng
authors.initials: X
authors.lastname: Yao
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kurihara
mesh_terms: D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D019684:Magnoliopsida / Q000737:chemistry*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D055611:Natural Killer T-Cells / Q000187:drug effects / Q000276:immunology; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000187:drug effects / Q000276:immunology
chemical_list: D004365:Drugs, Chinese Herbal