One-pot synthesis of N-arylpyrazoles from arylhalides.
A simple one-pot method for the synthesis of diversely functionalized pyrazoles from aryl nucleophiles, di-tert-butylazodicarboxlate, and 1,3-dicarbonyl or equivalent compounds is presented.
Gerstenberger
Brian S
BS
Pfizer Global Research and Development, 445 Eastern Point Road, Groton, Connecticut 06340, USA. brian.gerstenberger@pfizer.com
Rauckhorst
Mark R
MR
Starr
Jeremy T
JT
D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
D006846:Hydrocarbons, Halogenated; D011720:Pyrazoles