title: Hypereosinophilic syndrome in childhood: clinical and molecular features of two cases.
abstract: Hypereosinophilic syndrome (HES) represents a heterogeneous group of diseases, some of which are being clarified by recent advances in molecular genetics. It is very rare in children. Uncertainties in classification and lack of prospective studies make therapeutic decisions difficult. The authors report two cases of HES in which steroid therapy was effective.
authors.affiliation: Pediatric Hematology & Oncology, G. Di Cristina Children's Hospital, Palermo, Italy. farruggia.oep@ospedalecivicopa.org
authors.forename: Piero
authors.initials: P
authors.lastname: Farruggia
authors.forename: Paolo
authors.initials: P
authors.lastname: D'Angelo
authors.forename: Antonio
authors.initials: A
authors.lastname: Acquaviva
authors.forename: Antonino
authors.initials: A
authors.lastname: Trizzino
authors.forename: Fabio
authors.initials: F
authors.lastname: Tucci
authors.forename: Daniela
authors.initials: D
authors.lastname: Cilloni
authors.forename: Francesca
authors.initials: F
authors.lastname: Messa
authors.forename: Alfonso
authors.initials: A
authors.lastname: D'Ambrosio
authors.forename: Maurizio
authors.initials: M
authors.lastname: Aricò
mesh_terms: D001856:Bone Marrow Examination; D002648:Child; D020732:Cytogenetic Analysis; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013256:Steroids; D011241:Prednisone