Crystal structures, DNA-binding studies and antioxidant  activities of the Ln(III) complexes with 7-methoxychromone-  3-carbaldehyde-isonicotinoyl hydrazone.
The neutral mononuclear Ln(III) complexes (Ln = La, Sm) with 7-methoxychrom-one-3-carbaldehyde-isonicotinoyl hydrazone ligand (L) have been synthesized, characterized and investigated their interactions with calf-thymus DNA. The results show that the binding affinity of the La(III) complex is stronger than that of the Sm(III) complex and that of the ligand (L). Furthermore, the antioxidant activities of the ligand (L) and its Ln(III) complexes (Ln = La, Sm) were studied in detail.
Wang
Qian
Q
College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, 730000 Lanzhou, People's Republic of China.
Yang
Zheng-Yin
ZY
Qi
Gao-Fei
GF
Qin
Dong-Dong
DD
D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis / Q000378:metabolism*; D001665:Binding Sites; D002417:Cattle; D002867:Chromones / Q000737:chemistry; D003460:Crystallization; D018360:Crystallography, X-Ray; D004247:DNA / Q000378:metabolism*; D006835:Hydrazones / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry / Q000378:metabolism*; D008024:Ligands; D008958:Models, Molecular; D012493:Samarium / Q000737:chemistry / Q000378:metabolism*; D012545:Schiff Bases / Q000138:chemical synthesis / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013054:Spectrophotometry, Atomic
D000975:Antioxidants; D002867:Chromones; D006835:Hydrazones; D008024:Ligands; D012545:Schiff Bases; D012493:Samarium; D007811:Lanthanum; D004247:DNA; C427203:calf thymus DNA