title: Z-palatopharyngoplasty for obstructive sleep apnea/hypopnea syndrome.
abstract: OBJECTIVE
  To explore the feasibility, outcomes, and factors affecting the outcome of Z-palatopharyngoplasty (ZP3) in the treatment of severe obstructive sleep apnea/hypopnea syndrome (OSAHS).
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  ZP3 was performed on 34 Friedman stage II/III OSAHS patients with a posterior airway space (PAS) > or = 11 mm. Postoperative follow-up was at least 6 months, and the differences between responders and nonresponders were analyzed.
  
  
  RESULTS
  On the basis of success criteria, defined as an apnea-hypopnea index < 20 and a decrease > 50 percent, the success rate was 64.7 percent. The lowest oxygen saturation (LSaO(2)), percentage of time with an oxyhemoglobin saturation below 90 percent (CT(90)), mandibular plane angle (MPA), mandibular body length, position of the tongue, and Friedman clinical stage differed significantly between responders and nonresponders. The logistic regression analysis showed that MPA and Friedman stage were the key predictors of ZP3 surgical success. The best cutoff points for LSaO(2), CT(90), and MPA were 72 percent, 22.80 percent, and 29.40 degrees , respectively.
  
  
  CONCLUSIONS
  Factors affecting the outcome of ZP3 included LSaO(2), CT(90), MPA, mandibular body length, position of the tongue, and Friedman clinical stage. Of these, the MPA and Friedman clinical stage were most influential.
authors.affiliation: Department of Otorhinolaryngology, Affiliated Shanghai Sixth People's Hospital of Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Hong L
authors.initials: HL
authors.lastname: Yi
authors.forename: Shan K
authors.initials: SK
authors.lastname: Yin
authors.forename: Yu J
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Wen Y
authors.initials: WY
authors.lastname: Lu
authors.forename: Xiao Q
authors.initials: XQ
authors.lastname: Sun
authors.forename: Zhen Y
authors.initials: ZY
authors.lastname: Cao
authors.forename: Hong M
authors.initials: HM
authors.lastname: Wu
authors.forename: Jian
authors.initials: J
authors.lastname: Guan
mesh_terms: D000328:Adult; D002508:Cephalometry; D016009:Chi-Square Distribution; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D021362:Palate, Hard / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D012372:ROC Curve; D019651:Plastic Surgery Procedures / Q000379:methods*; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D010100:Oxygen