Metal-Brønsted acid cooperative catalysis for asymmetric reductive amination.
Direct reductive amination of a wide range of ketones has been accomplished by the cooperative catalysis of an Ir(III)-diamine complex and a chiral phosphoric acid or its conjugate base.
Li
Chaoqun
C
Liverpool Centre for Materials and Catalysis, Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Villa-Marcos
Barbara
B
Xiao
Jianliang
J
D000586:Amination; D000588:Amines / Q000138:chemical synthesis*; D000814:Aniline Compounds / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D007495:Iridium / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry
D000588:Amines; D000814:Aniline Compounds; D007659:Ketones; D009942:Organometallic Compounds; D007495:Iridium