title: Language networks in children: evidence from functional MRI studies.
abstract: OBJECTIVE
  The purpose of our study was to review functional MRI and other neuroimaging studies of language skills in children from infancy to adulthood.
  
  
  CONCLUSIONS
  Functional MRI (fMRI) and other neuroimaging studies show developmental changes in the networks of brain regions supporting language, which can be affected by brain injuries or neurologic disorders. Particular aspects of language rely on networks that lateralize to the dominant hemisphere; others rely on bilateral or nondominant mechanisms. Multiple fMRI tasks for pediatric patients characterize functional brain reorganization that may accompany language deficits.
authors.affiliation: Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital Research Foundation and Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-5033, USA. Jennifer.vannest@cchmc.org
authors.forename: Jennifer
authors.initials: J
authors.lastname: Vannest
authors.forename: Prasanna R
authors.initials: PR
authors.lastname: Karunanayaka
authors.forename: Vincent J
authors.initials: VJ
authors.lastname: Schmithorst
authors.forename: Jerzy P
authors.initials: JP
authors.lastname: Szaflarski
authors.forename: Scott K
authors.initials: SK
authors.lastname: Holland
mesh_terms: D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000503:physiopathology*; D001931:Brain Mapping; D002648:Child; D002675:Child, Preschool; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007223:Infant; D007804:Language Development; D007805:Language Development Disorders / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D009473:Neuronal Plasticity / Q000502:physiology