title: Relapse with malignant transformation after chemotherapy for primary mediastinal seminoma: case report.
abstract: This case report details a relapse with malignant transformation after the completion of bleomycin, etoposide and cisplatin chemotherapy for primary mediastinal seminoma, although the residual mass after chemotherapy was <3 cm in size and did not display an increased uptake of fluorodeoxyglucose when examined using positron emission tomography.
authors.affiliation: Division of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Iwasa
authors.forename: Masashi
authors.initials: M
authors.lastname: Ando
authors.forename: Makiko
authors.initials: M
authors.lastname: Ono
authors.forename: Taizo
authors.initials: T
authors.lastname: Hirata
authors.forename: Mayu
authors.initials: M
authors.lastname: Yunokawa
authors.forename: Eriko
authors.initials: E
authors.lastname: Nakano
authors.forename: Kan
authors.initials: K
authors.lastname: Yonemori
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Kouno
authors.forename: Chikako
authors.initials: C
authors.lastname: Shimizu
authors.forename: Kenji
authors.initials: K
authors.lastname: Tamura
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Katsumata
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujiwara
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000737:chemistry / Q000175:diagnosis / Q000209:etiology*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D018239:Seminoma / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin