title: Spontaneous formation of giant unilamellar vesicles from microdroplets of a polyion complex by thermally induced phase separation.
abstract: Water pump: Polyion complex (PIC) vesicles are spontaneously formed from PIC microdroplets, which are formed by mixing cationic and anionic polymers (see picture). The formation process can be reversibly controlled by local heating with a focused infrared laser that triggers microphase separation and subsequent water influx. The size of the resulting giant unilamellar vesicles is determined by the initial size of the PIC droplets.
authors.affiliation: Department of Mechanical Engineering, Graduate School of Engineering and Center for NanoBio Integration, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. oana@mech.t.u-tokyo.ac.jp
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Oana
authors.forename: Akihiro
authors.initials: A
authors.lastname: Kishimura
authors.forename: Kei
authors.initials: K
authors.lastname: Yonehara
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Yamasaki
authors.forename: Masao
authors.initials: M
authors.lastname: Washizu
authors.forename: Kazunori
authors.initials: K
authors.lastname: Kataoka
mesh_terms: D004337:Drug Carriers / Q000737:chemistry*; D006358:Hot Temperature; D057927:Hydrophobic and Hydrophilic Interactions; D007477:Ions / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D053835:Unilamellar Liposomes / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D007477:Ions; D053835:Unilamellar Liposomes; D011092:Polyethylene Glycols