title: Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT.
abstract: IgG antibody-transporter conjugates enable intracellular uptake of biologically active IgG antibodies that inhibit viral mediated syncytia formation in respiratory syncytial virus green fluorescent protein (RSV-GFP) infected human epithelial cells (HEp-2).
authors.affiliation: Department of Chemistry, 7619 Stevenson Center, Vanderbilt University, Nashville, TN, USA.
authors.forename: Sharon K
authors.initials: SK
authors.lastname: Hamilton
authors.forename: Mine R
authors.initials: MR
authors.lastname: Ikizler
authors.forename: Christian
authors.initials: C
authors.lastname: Wallen
authors.forename: Peter F
authors.initials: PF
authors.lastname: Wright
authors.forename: Eva
authors.initials: E
authors.lastname: Harth
mesh_terms: D000911:Antibodies, Monoclonal; D002352:Carrier Proteins; D045744:Cell Line, Tumor; D050091:Dendrimers / Q000737:chemistry; D049452:Green Fluorescent Proteins / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008958:Models, Molecular; D010865:Pilot Projects; D021381:Protein Transport; D018357:Respiratory Syncytial Virus Infections / Q000628:therapy; D018113:Respiratory Syncytial Virus, Human / Q000276:immunology; D013997:Time Factors; D014764:Viral Proteins
chemical_list: D000911:Antibodies, Monoclonal; D002352:Carrier Proteins; D050091:Dendrimers; D007074:Immunoglobulin G; D014764:Viral Proteins; D049452:Green Fluorescent Proteins