The efficacy of intraperitoneal saline infusion for percutaneous radiofrequency ablation for hepatocellular carcinoma.
OBJECTIVE
To evaluated the efficacy and safety of radiofrequency ablation (RFA) with intraperitoneal saline infusion.


BACKGROUND
Ultrasound-guided RFA is not always feasible due to the tumor location, possible adjacent tissue damage or poor sonographic identification.


METHODS
Ultrasound-guided RFA with intraperitoneal saline infusion was performed in 116 patients between June 2001 and March 2008.


RESULTS
The overall technical feasibility of the intraperitoneal saline infusions was 90.5% (105 patients). The purposes of the intraperitoneal saline infusion were achieved in 100 patients (86.2%) by visualizing the tumor located in hepatic dome (47 patients), prevent adjacent organ damage (42 patients) and withdrawing overlying omentum (10 patients). Complete ablation of tumor was accomplished in 102 patients (87.9%). Complications associated with the treatment occurred in seven patients (6.0%). There was no case of adverse event directly related to intraperitoneal saline infusion.


CONCLUSIONS
Intraperitoneal saline infusion is an effective and safe procedure that can be used to overcome the current limitations of ultrasound-guided RFA.
Park
Soo Young
SY
Department of Internal Medicine, Liver Research Institute, Graduate School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Tak
Won Young
WY
Jeon
Seong Woo
SW
Cho
Chang Min
CM
Kweon
Young Oh
YO
Kim
Sung Kook
SK
Choi
Yong Hwan
YH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007263:Infusions, Parenteral; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D012965:Sodium Chloride / Q000008:administration & dosage; D025321:Surgery, Computer-Assisted / Q000379:methods; D016896:Treatment Outcome; D014463:Ultrasonography / Q000187:drug effects / Q000379:methods*
D003287:Contrast Media; D012965:Sodium Chloride