title: Quality of life in opium-addicted patients with coronary artery disease as measured with WHOQOL-BREF.
abstract: OBJECTIVE
  Several factors can influence the quality of life in patients with coronary artery disease (CAD). The goal of this research was to measure quality of life in opium-addicted patients with CAD in order to assess the effect of CAD risk factors on their quality of life.
  
  
  METHODS
  The WHOQOL-BREF questionnaire was completed through interviews with 275 patients who underwent isolated coronary artery bypass surgery in Tehran Heart Centre between May and September 2006.
  
  
  RESULTS
  No significant differences were found in the mean scores of the four domains of quality of life between the addicted and non-addicted patients. Furthermore, the evaluation of QOL in the groups with CAD risk factors showed that the mean QOL domains were statistically similar between opium addicted and non-opium addicted patients. In the addicted group, men had a higher psychological health score than women. A previous history of myocardial infarction reduced the psychological score in this group. Also, in the addicted patients with a history of diabetes mellitus, social functioning was better than that of the non-diabetics.
  
  
  CONCLUSIONS
  The different domains of quality of life in our opium-addicted and non-addicted patients with CAD were similar; and among all the major risk factors for coronary artery disease, only female gender and a previous history of myocardial infarction could influence quality of life in the opium-addicted patients.
authors.affiliation: Tehran Heart Centre, Medical Sciences/University of Tehran, Iran.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Najafi
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Sheikhvatan
authors.forename: Ali
authors.initials: A
authors.lastname: Montazeri
authors.forename: Mahmood
authors.initials: M
authors.lastname: Sheikhfathollahi
mesh_terms: D000223:Adaptation, Psychological; D001294:Attitude to Health; D015897:Comorbidity; D003327:Coronary Disease / Q000453:epidemiology* / Q000523:psychology; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006304:Health Status; D006801:Humans; D007407:Interviews as Topic; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D009293:Opioid-Related Disorders / Q000453:epidemiology* / Q000523:psychology; D009892:Opium; D010555:Personality Inventory; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D012307:Risk Factors; D012737:Sex Factors; D012917:Social Adjustment; D011795:Surveys and Questionnaires
chemical_list: D009892:Opium