title: [Factor VII deficiency revealed by intracranial hemorrhage].
abstract: Constitutional factor VII deficiency is a hereditary disease with recessive autosomic transmission. Its incidence is estimated to be 1/1,000,000 in the general population. We report a case of severe factor VII deficiency in infancy revealed by an intracranial hemorrhage in a 2-month-old infant. We describe the clinical, biological and therapeutic characteristics of this disease.
authors.affiliation: Service de pédiatrie, CHU Hédi Chaker, 3029 Sfax, Tunisie. lamia_benmansour@yahoo.fr
authors.forename: L
authors.initials: L
authors.lastname: Sfaihi Ben Mansour
authors.forename: A
authors.initials: A
authors.lastname: Thabet
authors.forename: H
authors.initials: H
authors.lastname: Aloulou
authors.forename: H
authors.initials: H
authors.lastname: Turki
authors.forename: I
authors.initials: I
authors.lastname: Chabchoub
authors.forename: F
authors.initials: F
authors.lastname: Mhiri
authors.forename: Z
authors.initials: Z
authors.lastname: Mnif
authors.forename: H
authors.initials: H
authors.lastname: Ben Ali
authors.forename: T
authors.initials: T
authors.lastname: Kammoun
authors.forename: M
authors.initials: M
authors.lastname: Hachicha
mesh_terms: D061085:Agenesis of Corpus Callosum; D000941:Antigens / Q000627:therapeutic use; D002552:Cerebral Ventricles / Q000473:pathology; D002869:Chromosome Aberrations; D003131:Combined Modality Therapy; D003241:Consanguinity; D003337:Corpus Callosum / Q000473:pathology; D004453:Echoencephalography; D005167:Factor VII / Q000627:therapeutic use; D005168:Factor VII Deficiency / Q000175:diagnosis* / Q000235:genetics; D005808:Genes, Recessive; D006580:Genetic Carrier Screening; D006801:Humans; D007223:Infant; D020300:Intracranial Hemorrhages / Q000209:etiology* / Q000235:genetics / Q000601:surgery; D008297:Male; D009778:Occipital Lobe / Q000473:pathology; D011994:Recombinant Proteins / Q000627:therapeutic use; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt
chemical_list: D000941:Antigens; D011994:Recombinant Proteins; C042580:factor VII clotting antigen; D005167:Factor VII