title: [Directions of investigations for new drugs in asthma].
abstract: Bronchial asthma is affecting more than 300 million people worldwide and in every 15-20 years additional 100 million patients are expected. About 5-10% of asthmatic patients have severe disease and fails to respond to conventional therapy. For this reason a new therapy or improvement in available treatment are under investigations. More knowledge of asthma mechanisms has led to monoclonal antibody, inhaled anti-oxidants and new combination therapy with corticosteroids. Similarly, biological agents directed against IL-13 and immunomodulators influenced T-regulatory cells are likely to be successful in the future therapy.
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Płusa
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000975:Antioxidants / Q000008:administration & dosage; D001249:Asthma / Q000188:drug therapy*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000911:Antibodies, Monoclonal; D000975:Antioxidants; D007155:Immunologic Factors