anti-Oligoannelated THF moieties: synthesis via push-pull-substituted cyclopropanes.
The first synthesis of anti-fused oligoannelated THF moieties is reported. The key transformation of the synthetic sequence, consisting of cyclopropanation, reduction and oxidation, is the expansion of a push-pull-substituted three-membered ring into a five-membered enol ether system. A repetition of the sequence allows the creation of oligoacetals up to a nonacyclic system.
Schneider
Tobias F
TF
Institut für Organische and Biomolekulare Chemie der Georg-August-Universität Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany.
Kaschel
Johannes
J
Dittrich
Birger
B
Werz
Daniel B
DB