title: Sarcoma development after radiotherapy in two dogs.
abstract: Two dogs were treated with a hypofractionated course of radiotherapy following surgical excision of an intermediate grade mast cell tumour and a round cell tumour, respectively. Both dogs developed a sarcoma of the bone, within the irradiated site, several years after the initial radiotherapy treatment. Bone tumours arising within a previously irradiated area are well-recognized late radiotherapy side-effect in humans but have been reported infrequently in dogs. These are the first case reports to describe bone sarcomas in the appendicular skeleton at a site, which had been previously treated by a hypofractionated course of radiotherapy for an unrelated tumour.
authors.affiliation: Queen's Veterinary School Hospital, University of Cambridge, Cambridge, UK. rjm69@cam.ac.uk
authors.forename: R J
authors.initials: RJ
authors.lastname: Mellanby
authors.forename: M E
authors.initials: ME
authors.lastname: Herrtage
authors.forename: J
authors.initials: J
authors.lastname: Chantry
authors.forename: J M
authors.initials: JM
authors.lastname: Dobson