[Relationship of nonsyndromic cleft lip and/or palate and poliovirus receptor-related 1 exon 3 polymorphisms in Han people of Jiangzhe area].
OBJECTIVE
To study the relationship of nonsyndromic cleft lip and/or palate (NSCL/P) and poliovirus receptor-related 1 exon3 (PVRL1exon3) polymorphisms in Han People of Jiangzhe area.


METHODS
PVRL1exon3 was examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique in the 50 patients with NSCL/P and 85 healthy parents.


RESULTS
No W185X mutation was found in the PVRL1exon 3.


CONCLUSIONS
It indicates that there is no relationship between NSCL/P and PVRL1exon3 in Han People in Jiangzhe area.
Zhao
Xiong
X
Department of Burns, the Children' s Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Jiang
Run-song
RS
Liu
Rui
R
Ye
Wen-song
WS
Wang
Ning
N
Shang
Shi-qiang
SQ
Dai
Ye-feng
YF
Zhao
Xu-fei
XF
D044466:Asian People / Q000235:genetics; D015815:Cell Adhesion Molecules / Q000235:genetics*; D002675:Child, Preschool; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics*; D005091:Exons; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D000075983:Nectins; D010375:Pedigree; D011110:Polymorphism, Genetic; D011991:Receptors, Virus / Q000235:genetics
D015815:Cell Adhesion Molecules; C000619010:NECTIN1 protein, human; D000075983:Nectins; D011991:Receptors, Virus