title: Gastro-oesophageal reflux and "epileptic" attacks: casually associated or related? Efficiency of antireflux surgery: a case report.
abstract: Although a possible link between gastro-oesophageal reflux disease (GORD) and obstructive sleeping apnoea has already been reported in the literature, there has never been any suggestion of an association with epilepsy, and epileptic attacks have not so far been included among gastro-oesophageal reflux disease symptoms. We report the case of a patient with gastro-oesophageal reflux disease associated with a sliding hiatus hernia, a short oesophagus and oesophagitis, who for the last ten years had not only presented the typical symptoms of gastrooesophageal reflux, but also symptoms of obstructive sleep apnoea and epileptic-like attacks occurring occasionally and only during sleep. Partial posterior fundoplication was performed and considerably reduced the reflux symptoms, and in addition brought about a drastic decrease in the number of epileptic-like attacks. Our case suggests that epileptic-like episodes in patients with obstructive sleeping apnoea may well be linked to the simultaneous presence of GORD associated with hiatus hernia, and surgical treatment of GORD may bring about an improvement of the neurological problems.
authors.affiliation: Dipartimento di Chirurgia Oncologica, Policlinico Universitario, Palermo.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Fiorentino
authors.forename: Gianni
authors.initials: G
authors.lastname: Pantuso
authors.forename: Alessia
authors.initials: A
authors.lastname: Cusimano
authors.forename: Stefania
authors.initials: S
authors.lastname: Latteri
authors.forename: Achille
authors.initials: A
authors.lastname: Mastrosimone
authors.forename: Calogero
authors.initials: C
authors.lastname: Cipolla
mesh_terms: D000328:Adult; D004827:Epilepsy / Q000209:etiology*; D005500:Follow-Up Studies; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000601:surgery*; D006551:Hernia, Hiatal / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011859:Radiography; D012891:Sleep Apnea Syndromes / Q000209:etiology*; D013997:Time Factors; D016896:Treatment Outcome