[Video-assisted thoracoscopic extended thymectomy and transsternal extended thymectomy for treatment of myasthenia gravis: a case-control study].
OBJECTIVE
To compare the therapeutic effects of video-assisted thoracoscopic extended thymectomy (VATET) and transsternal extended thymectomy (TET) for myasthenia gravis (MG).


METHODS
This study included 21 patients undergoing VATET through the "three holes" approach on the right chest and 32 undergoing TET with sternum dissection. The thymus was excised and the anterior mediastinum adipose tissue removed in both groups.


RESULTS
VATET was associated with reduced intraoperative blood loss and longer operative time without the use of postoperative analgesics; very few patients were admitted into the intensive care unit (ICU), showing significant differences from the TET group (P<0.05). No significant difference was found between the two groups in tracheal tube removal time, length of stay in ICU, closed thoracic drainage removal time, and postoperative hospital stay, total hospital stay, postoperative complications, total hospitalization costs, or the rate of remission and improvement (P>0.05).


CONCLUSIONS
Compared with TET, VATET requires only a small incision without leaving metal foreign body in the body, and the patients experience less postoperative pain and rapid recovery, with similar mid- and long-term clinical outcomes.
Zuo
Ji-dong
JD
Department of Minimal Invasive Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. zuojd@126.com
Chen
Zhen-guang
ZG
Liu
Wei-bin
WB
Tan
Min
M
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D009157:Myasthenia Gravis / Q000601:surgery*; D011183:Postoperative Complications; D020775:Thoracic Surgery, Video-Assisted / Q000009:adverse effects / Q000379:methods*; D013934:Thymectomy / Q000009:adverse effects / Q000379:methods*; D055815:Young Adult