[Determination of Cr, Cd, As, Tl and Pb in blood by inductively coupled plasma mass spectrometry].
OBJECTIVE
To establish an inductively coupled plasma mass spectrometry (ICP-MS) method for determination of Cr, Cd, As, Tl and Pb in blood.


METHODS
The samples were digested by microwave digestion instrument. ICP-MS was applied to determine Cr, Cd, As, Tl and Pb in blood by using 115In as an internal standard.


RESULTS
The limits of detection were in the range of 0.00001-0.00249 microg/L. The accuracy of the method ranged from 90.1% to 110.7% and the precision ranged from 4.0% to 7.9%.


CONCLUSIONS
The method is accurate and rapid with superior sensitivity and linear range. It could be used in the poisoning cases caused by Cr, Cd, As, Tl and Pb.
Ma
Dong
D
Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China. madong@ssfjd.cn
Shen
Min
M
Zhuo
Xian-yi
XY
Yan
Hui
H
Xiang
Ping
P
Liu
Wei
W
D001151:Arsenic / Q000097:blood; D002104:Cadmium / Q000097:blood; D002857:Chromium / Q000097:blood; D053593:Forensic Toxicology; D006801:Humans; D007854:Lead / Q000097:blood; D013058:Mass Spectrometry / Q000379:methods*; D019216:Metals, Heavy / Q000097:blood*; D014025:Titanium / Q000097:blood
D019216:Metals, Heavy; D002104:Cadmium; D002857:Chromium; D007854:Lead; D014025:Titanium; D001151:Arsenic