title: Trichinellosis, a threatening and re-emerging disease in a Romanian western county.
abstract: BACKGROUND
  Trichinellosis is frequently reported in east European countries like Romania, where the yearly incidence during 1990-1999 was 5.5 cases/100,000 inhabitants. Arad, a western Romanian county, is known as one of the most endemic regions of trichinellosis. A major and unforgettable epidemic of trichinellosis has developed at the beginning of 1973 in this county. The present study focuses on human trichinellosis patients from Arad County, emphasizing on epidemiological, clinical, laboratory, and therapeutic aspects.
  
  
  METHODS
  Retrospective analysis of the medical records of 335 patients found to have trichinellosis during 1996-2006 and hospitalized in Arad County. The mean age of the trichinellosis patients was 33.6 years, and majority (64.8%) were inhabitants of the rural areas.
  
  
  RESULTS
  Winter was the season with the highest number of cases (71.6%). Fever was the most frequent manifestation of the disease (85.4%), followed by myalgia (83%). Eosinophilia ranged predominantly between 20% and 20.99% (19.4%). Albendazole was the specific drug administered in 49.4% of the patients.
  
  
  CONCLUSIONS
  Trichinellosis still remains a concern and a major issue of public health in Arad County. Implementation of strict hygienic measures, especially in the rural areas, must be a priority.
authors.affiliation: Victor Babes University of Medicine and Pharmacy, Timisoara, Romania. raul.neghina@gmail.com
authors.forename: Raul
authors.initials: R
authors.lastname: Neghina
authors.forename: Adriana M
authors.initials: AM
authors.lastname: Neghina
authors.forename: Iosif
authors.initials: I
authors.lastname: Marincu
authors.forename: Roxana
authors.initials: R
authors.lastname: Moldovan
authors.forename: Ioan
authors.initials: I
authors.lastname: Iacobiciu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015766:Albendazole / Q000627:therapeutic use; D000704:Analysis of Variance; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D021821:Communicable Diseases, Emerging / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D020387:Food Chain; D006801:Humans; D008297:Male; D008460:Meat / Q000469:parasitology; D008499:Medical Records; D008875:Middle Aged; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012621:Seasons; D013552:Swine / Q000469:parasitology; D014235:Trichinellosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000871:Anthelmintics; D015766:Albendazole