Gestational diabetes mellitus: developments in diagnosis and treatment.
After many years of uncertainty regarding the true pathological nature of mild gestational diabetes and the possible benefits of treatment, the situation appears to have been resolved by the publication of the Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS). It is now appropriate for obstetric units to review their treatment and screening programs for gestational diabetes mellitus. Furthermore, with the publication of the Metformin in Gestational Diabetes (MiG) trial, consideration should be given as to whether metformin should be the first choice when diet fails to maintain glycemic control.
Fraser
Robert
R
University of Sheffield, The Jessop Wing, Sheffield, UK. g.m.burkinshaw@sheffield.ac.uk
D000653:Amniotic Fluid / Q000737:chemistry; D016640:Diabetes, Gestational / Q000175:diagnosis / Q000178:diet therapy / Q000188:drug therapy; D005260:Female; D005315:Fetal Diseases / Q000209:etiology; D006801:Humans; D006946:Hyperinsulinism / Q000196:embryology / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000032:analysis / Q000627:therapeutic use; D008687:Metformin / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011256:Pregnancy Outcome; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin