ACTH therapy in refractory generalized epilepsy.
Adrenocorticotropic hormone (ACTH) has a long track record for the treatment of infantile spasms. However, there is paucity of data on the use of ACTH in the treatment of epilepsy beyond infantile spasms. We report the use of ACTH in two children with refractory generalized epilepsy. Both patients responded well. ACTH may be considered as a useful adjunctive therapy in patients with intractable generalized seizures. Side effects and cost however, remain important concerns.
Kalra
Veena
V
Division of Child Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Sharma
Suvasini
S
Arya
Ravindra
R
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male
D000324:Adrenocorticotropic Hormone