title: Mixed f-d coordination complexes as dual visible- and near-infrared-emitting probes for targeting DNA.
abstract: A new family of mixed-lanthanide (Yb(III) and Nd(III)) transition-metal (f-d) cyclen-Ru(II)(phen)(3) (phen = 1,10-phenanthroline) complexes were synthesized as dual visible- and near-infrared (NIR)-emitting DNA probes/sensors. Significant changes were seen in both the Ru(II) visible and the Yb(III)-centered NIR emission, which was switched off upon binding to DNA at pH 7.4. In contrast, no changes were seen in the Nd(III) emission of the analogue f-d conjugate.
authors.affiliation: School of Chemistry, Center for Synthesis and Chemical Biology, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Aline M
authors.initials: AM
authors.lastname: Nonat
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Quinn
authors.forename: Thorfinnur
authors.initials: T
authors.lastname: Gunnlaugsson
mesh_terms: D004247:DNA / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D015342:DNA Probes; D028581:Lanthanoid Series Elements; D009942:Organometallic Compounds; D012428:Ruthenium; D004247:DNA