title: [Auditory P300 in the patients with traumatic brain injury].
abstract: OBJECTIVE
  To assess the cognitive dysfunction in patients with the traumatic brain injury (TBI) by auditory P300.
  
  
  METHODS
  Auditory P300 was recorded in the normal subjects and patients with TBI at the active (foot pedal) and passive task.
  
  
  RESULTS
  In healthy persons, N2 and P3 in active task state showed higher amplitude than that in passive task state, and no significant prolongation of the latency. The amplitude of N1 and P2 at Cz was higher than that at Pz. In passive task state, N2 and P3 showed higher amplitude and longer latency in the patients than that in the healthy persons. N2 and P3 of the patients in the active task showed higher amplitude and longer latency than that in the passive task. Obvious change of P3 latency was observed in the patients with attention disorder.
  
  
  CONCLUSIONS
  The type of task mainly affect the amplitude of N2 and P3. The latency of N2 and P3 in passive task can be used as an indication for evaluating cognitive function in patients with diffuse brain injury.
authors.affiliation: Department of Clinical Forensic Medicine, School of Forensic Medicine, China Medical University, Shenyang 110001, China. cuiyong1288@sina.com
authors.forename: Yong
authors.initials: Y
authors.lastname: Cui
authors.forename: Fan
authors.initials: F
authors.lastname: Liu
authors.forename: Xin-yuan
authors.initials: XY
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Tang
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.forename: Biao
authors.initials: B
authors.lastname: Zhang
authors.forename: Ji-hui
authors.initials: JH
authors.lastname: Liu
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D055815:Young Adult