title: Knowledge of developmental pharmacology and modeling approaches should be used to avoid useless trials in children.
authors.forename: Saskia N
authors.initials: SN
authors.lastname: de Wildt
authors.forename: Catherijne A J
authors.initials: CA
authors.lastname: Knibbe
mesh_terms: D000367:Age Factors; D002648:Child; D002657:Child Development; D002986:Clinical Trials as Topic / Q000592:standards; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D017277:Drug Approval; D006801:Humans; D015233:Models, Statistical; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D054328:Proton Pump Inhibitors