Improved long-term prognosis of elderly women in the era of sirolimus-eluting stents.
BACKGROUND
The angiographic characteristics and prognosis in elderly women in relation to the therapeutic impact of sirolimus-eluting stents (SES) need to be clarified.


RESULTS
Quantitative coronary angiography analysis was performed in 1,374 patients with coronary artery disease: 670 patients were treated with a bare metal stent (BMS) and the remaining 704 were treated with SES. Patients were divided into 4 groups according to gender and age (<75 years M/F, > or =75 years M/F), and major adverse cardiovascular events (MACE) were compared among them. Women > or =75 years old tended to have 3-vessel disease with small vessel size and the incidence of MACE in this group was high in the BMS era. However, in the SES era, this prognosis improved by reducing all-cause death and target vessel revascularization.


CONCLUSIONS
Using SES has a therapeutic advantage for the high-risk population of elderly women with angiographically unsuitable lesions for percutaneous coronary intervention.
Kataoka
Yu
Y
Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, Suita, Japan.
Yasuda
Satoshi
S
Morii
Isao
I
Kawamura
Atsushi
A
Miyazaki
Shunichi
S
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D000900:Anti-Bacterial Agents; D002318:Cardiovascular Diseases / Q000517:prevention & control; D000075202:Contraindications; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D012737:Sex Factors; D020123:Sirolimus; D015607:Stents
D000900:Anti-Bacterial Agents; D020123:Sirolimus