[Polymorphism of pigmentation genes (OCA2 and ASIP) in some populations of Russia].
In Russian populations, polymorphism of two pigmentation system genes, OCA2 (loci 305, 355, and 419, tested in Russians, Buryats, Chukchi, Koryaks, and Evens) and ASIP (locus 8818, tested in Russians and Buryats) was examined. Pairwise comparisons of the F(ST) distances between the populations showed that only the populations from Northeast Asia (Chukchi, Koryaks, and Evens) were statistically significantly different from all other populations, at least relative to one of the OCA2 locus. In Russians from Pskov oblast and Novgorod oblast, increased frequency (up to 6%) of the OCA2 allele 419A was revealed. In earlier studies, as association of this allele with green eye color was demonstrated. The data obtained in terms of their application for ethnic population genetics.
Maliarchuk
B A
BA
Perkova
M A
MA
Derenko
M V
MV
D054366:Agouti Signaling Protein / Q000235:genetics*; D000483:Alleles; D005006:Ethnicity / Q000235:genetics*; D005127:Eye Color / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D006801:Humans; D008297:Male; D026901:Membrane Transport Proteins / Q000235:genetics*; D011110:Polymorphism, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics; D012426:Russia
C515182:ASIP protein, human; D054366:Agouti Signaling Protein; D026901:Membrane Transport Proteins; C489600:OCA2 protein, human