Successful treatment of multi-drug resistant tuberculosis by double lung transplantation.
A 24-year-old man suffering from end-stage, multi-drug, resistant tuberculosis and right heart failure underwent bilateral, single-lung transplantation with extracorporeal membrane oxygenator support. He was successfully weaned and discharged from the hospital 30 days later. Sputum cultures have been negative for tuberculosis since discharge, and for almost 2 years thereafter. Anti-tuberculosis medication was discontinued 4 months postoperatively.
Chen
Jing-yu
JY
Lung Transplant Group, Wuxi People's Hospital, Wuxi, China. chenjingyu333@yahoo.com.cn
Zhu
Yan-hong
YH
Jin
Chao-hui
CH
Zheng
Ming-feng
MF
Zhang
Ji
J
Zhou
Min
M
D000995:Antitubercular Agents / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery*; D055815:Young Adult
D000995:Antitubercular Agents