title: Role of ischemic preconditioning in liver surgery and hepatic transplantation.
abstract: BACKGROUND
  The purpose of this review is to summarize intraoperative surgical strategies available to decrease ischemia-reperfusion injury associated with liver resection and liver transplantation.
  
  
  METHODS
  We conducted a critical review of the literature evaluating the potential applications of hepatic ischemic preconditioning (IPC) for hepatic resection surgery and liver transplantation. In addition, we provide a basic bench-to-bedside summary of the liver physiology and cell signaling mechanisms that account for the protective effects seen with hepatic IPC.
authors.affiliation: Departamento de Cirugía, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM) y Servicio de Cirugía General del Hospital General de México, Mexico City, Mexico.
authors.forename: Eduardo E
authors.initials: EE
authors.lastname: Montalvo-Jave
authors.forename: Enrique
authors.initials: E
authors.lastname: Piña
authors.forename: Cesar
authors.initials: C
authors.lastname: Montalvo-Arenas
authors.forename: Raúl
authors.initials: R
authors.lastname: Urrutia
authors.forename: Luis
authors.initials: L
authors.lastname: Benavente-Chenhalls
authors.forename: Julieta
authors.initials: J
authors.lastname: Peña-Sanchez
authors.forename: David A
authors.initials: DA
authors.lastname: Geller
mesh_terms: D000818:Animals; D005234:Fatty Liver / Q000503:physiopathology; D006498:Hepatectomy; D022781:Hepatocytes / Q000502:physiology; D006801:Humans; D019194:Ischemic Preconditioning / Q000379:methods; D008099:Liver / Q000503:physiopathology; D008102:Liver Circulation; D016031:Liver Transplantation / Q000502:physiology; D009569:Nitric Oxide / Q000378:metabolism; D011300:Preoperative Care; D012039:Regional Blood Flow; D015427:Reperfusion Injury / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D009569:Nitric Oxide