title: Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion.
abstract: OBJECTIVE
  This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro.
  
  
  METHODS
  Bovine enamel samples were submitted to a cyclic de- and remineralisation for 3 days. Each day, the samples were exposed for 120 min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3 min: amine fluoride (AmF, 0.5% and 1% F(-)), sodium fluoride (NaF, 0.5% and 1% F(-)), each at pH 3.9 and 7.0, and stannous fluoride (SnF(2), 0.5% and 1% F(-)), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation). Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90 s each intermitted by exposure to artificial saliva (1h). After 3 days, enamel loss was analyzed profilometrically and evaluated statistically by ANOVA.
  
  
  RESULTS
  Only the acidic 0.5% and 1% SnF(2) and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF(2) and the 1% AmF solutions no significant differences could be detected.
  
  
  CONCLUSIONS
  At the same concentrations, acidic SnF(2) and AmF may be more effective than NaF to protect enamel against erosion.
authors.affiliation: Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland. annette.wiegand@zzmk.unizh.ch
authors.forename: Annette
authors.initials: A
authors.lastname: Wiegand
authors.forename: Dominique
authors.initials: D
authors.lastname: Bichsel
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Magalhães
authors.forename: Klaus
authors.initials: K
authors.lastname: Becker
authors.forename: Thomas
authors.initials: T
authors.lastname: Attin
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002417:Cattle; D003743:Dental Enamel / Q000187:drug effects*; D044622:Dental Pellicle / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000737:chemistry; D014002:Tin Fluorides / Q000008:administration & dosage / Q000737:chemistry; D017001:Tooth Demineralization / Q000209:etiology / Q000517:prevention & control*; D014077:Tooth Erosion / Q000628:therapy*; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D005460:Fluorides, Topical; D014002:Tin Fluorides; C094808:amine fluoride solution; D012969:Sodium Fluoride