[Isolated conjunctival involvement in Langerhans cell histiocytosis].
METHODS
A 43-year-old woman referred for a hyperemic node in the inferior conjunctival fornix. No improvement was observed after 10 days of antibiotic and anti-inflammatory topical treatment, so biopsy-extirpation was performed. Histopathological and immunohistochemical findings suggested the diagnosis of Langerhans cell histiocytosis (LCH). No findings of extraocular manifestations were shown after an intensive clinical and analytical investigation.


CONCLUSIONS
LCH is a disease with different organ manifestations whose diagnosis depends on histological findings. We present a patient with isolated conjunctival affectation, which to our knowledge is the third case published in the literature.
López-Molina
M
M
Servicio de Oftalmología, Complejo Hospitalario Universitario de Albacete, Albacete, España. mercedeslopezmolina@hotmail.com
Méndez-Llatas
M
M
Sáez-Méndez
L
L
Escario-Travesedo
E
E
Sotoca-Fernández
J V
JV
Blanco-Marchite
C
C
D000328:Adult; D018949:Antigens, CD1 / Q000032:analysis; D015415:Biomarkers; D003229:Conjunctival Diseases / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006940:Hyperemia / Q000209:etiology; D009418:S100 Proteins / Q000032:analysis
D018949:Antigens, CD1; D015415:Biomarkers; C419393:CD1a antigen; D009418:S100 Proteins