title: [The role of lymphocyte-platelet adhesions, cytokines and endothelial dysfunction in pathogenesis of cold-induced lesions].
abstract: We studied the role of lymphocyte-platelet adhesion, IL-1beta, TNFalpha and endothelial dysfunction in pathogenesis of damage in local frostbites. Examination of 60 patients aged 17-50 years with frostbites of the second-forth degree has demonstrated that in patients with local frostbites the number of lymphocyte-platelet adhesions, circulating desquamated endothelial cells increases as well as the level of proinflammatory cytokines, while nitrites concentration decreases.
authors.forename: K G
authors.initials: KG
authors.lastname: Shapovalov
authors.forename: E A
authors.initials: EA
authors.lastname: Tomina
authors.forename: M I
authors.initials: MI
authors.lastname: Mikhaĭlichenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Vitkovskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D001792:Blood Platelets / Q000166:cytology / Q000276:immunology*; D016022:Case-Control Studies; D002448:Cell Adhesion / Q000276:immunology; D016207:Cytokines / Q000097:blood / Q000276:immunology*; D004730:Endothelium, Vascular / Q000276:immunology* / Q000473:pathology; D005627:Frostbite / Q000097:blood / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D016207:Cytokines