title: DNA replication reaches the breaking point.
abstract: DNA strand breaks that result in stalled or damaged replication forks can be detrimental to the DNA replication process. In this issue, Doksani et al. (2009) examine the impact of a single double-stranded DNA break on replication in the budding yeast, Saccharomyces cerevisiae.
authors.affiliation: Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA. petrinij@mskcc.org
authors.forename: John H J
authors.initials: JH
authors.lastname: Petrini
mesh_terms: D053903:DNA Breaks, Double-Stranded; D004261:DNA Replication; D016196:S Phase; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000235:genetics* / Q000378:metabolism