title: Three new triterpenoid saponins from the leaves and stems of Panax quinquefolium.
abstract: Three new minor dammarane saponins, quinquenosides L10 (1), L14 (2), and L16 (3), were isolated from the leaves and stems of Panax quinquefolium L. By the combination of one- and two-dimensional NMR techniques and MS spectroscopic analysis, their structures were established as 20-O-(alpha-L-arabinopyranosyl-(1-6)-O-beta-D-glucopyranosyl)-3-O-beta-D-glucopyranosyl-dammar-24-ene-3,12, 20-triol (1), 20-O-alpha-L-arabinopyranosyl-3-O-(beta-D-glucopyranosyl-(1-2)-O-beta-d-glucopyranosyl)-dammar-24-ene-3,12,20-triol (2), 3-O-(beta-D-glucopyranosyl-(1-2)-O-beta-d-glucopyranosyl)-20-O-(beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranosyl)-dammarane-3,12,20,24,25-pentaol (3). The content of artemisinin was significantly enhanced by 3.0 mg l(- 1) of compounds 1, 2, and 3 in the callus of Artemisia annua.
authors.affiliation: Department of Natural Medicines, Shenyang Pharmaceutical University, Shenyang, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.forename: Rui
authors.initials: R
authors.lastname: Zhao
authors.forename: Yi-Mei
authors.initials: YM
authors.lastname: Zeng
authors.forename: Hei
authors.initials: H
authors.lastname: Meng
authors.forename: Wen-Jian
authors.initials: WJ
authors.lastname: Zuo
authors.forename: Xian
authors.initials: X
authors.lastname: Li
authors.forename: Jin-Hui
authors.initials: JH
authors.lastname: Wang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D036145:Ginsenosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D005894:Panax / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D000097669:Dammaranes
chemical_list: D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D014315:Triterpenes; D000097669:Dammaranes; C540460:quinquenoside L10; C540461:quinquenoside L14; C540462:quinquenoside L16