title: Crystal structures, DNA-binding studies and antioxidant  activities of the Ln(III) complexes with 7-methoxychromone-  3-carbaldehyde-isonicotinoyl hydrazone.
abstract: The neutral mononuclear Ln(III) complexes (Ln = La, Sm) with 7-methoxychrom-one-3-carbaldehyde-isonicotinoyl hydrazone ligand (L) have been synthesized, characterized and investigated their interactions with calf-thymus DNA. The results show that the binding affinity of the La(III) complex is stronger than that of the Sm(III) complex and that of the ligand (L). Furthermore, the antioxidant activities of the ligand (L) and its Ln(III) complexes (Ln = La, Sm) were studied in detail.
authors.affiliation: College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, 730000 Lanzhou, People's Republic of China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Zheng-Yin
authors.initials: ZY
authors.lastname: Yang
authors.forename: Gao-Fei
authors.initials: GF
authors.lastname: Qi
authors.forename: Dong-Dong
authors.initials: DD
authors.lastname: Qin
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis / Q000378:metabolism*; D001665:Binding Sites; D002417:Cattle; D002867:Chromones / Q000737:chemistry; D003460:Crystallization; D018360:Crystallography, X-Ray; D004247:DNA / Q000378:metabolism*; D006835:Hydrazones / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry / Q000378:metabolism*; D008024:Ligands; D008958:Models, Molecular; D012493:Samarium / Q000737:chemistry / Q000378:metabolism*; D012545:Schiff Bases / Q000138:chemical synthesis / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013054:Spectrophotometry, Atomic
chemical_list: D000975:Antioxidants; D002867:Chromones; D006835:Hydrazones; D008024:Ligands; D012545:Schiff Bases; D012493:Samarium; D007811:Lanthanum; D004247:DNA; C427203:calf thymus DNA