Attribution of malnutrition to cause-specific diarrheal illness: evidence from a prospective study of preschool children in Mirpur, Dhaka, Bangladesh.
We examined whether malnutrition (underweight [WAZ] < -2) increased the risk of diarrhea equally for all enteropathogens. The study was conducted prospectively between January 1999 and July 2002 in Mirpur, an urban slum in Dhaka. Two hundred eighty-nine Bangladeshi children (147 male and 142 female) 2-5 years of age were included in the study. Malnutrition was present in 39% of the children at the time of enrollment. The parents and children were visited and interviewed every other day by health care workers for details about any diarrheal episodes. Stool samples were successfully collected from 62% of episodes of diarrhea. Of the identified enteropathogens, only enterotoxigenic Escherichia coli (ETEC), Cryptosporidium sp., and Entamoeba histolytica were significantly more prevalent in malnourished children. We concluded that the malnutrition attributed risk is not equal for enteric pathogens associated with diarrheal illness.
Mondal
Dinesh
D
International Centre For Diarrhoeal Disease Research, Bangladesh (ICDDR, B), Dhaka, Bangladesh.
Haque
Rashidul
R
Sack
R Bradley
RB
Kirkpatrick
Beth D
BD
Petri
William A
WA
D000818:Animals; D001424:Bacterial Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D001459:Bangladesh / Q000453:epidemiology; D015362:Child Nutrition Disorders / Q000150:complications* / Q000453:epidemiology*; D002675:Child, Preschool; D003457:Cryptosporidiosis / Q000150:complications / Q000453:epidemiology; D003967:Diarrhea / Q000150:complications* / Q000453:epidemiology* / Q000382:microbiology / Q000469:parasitology; D004749:Entamoebiasis / Q000150:complications / Q000453:epidemiology / Q000469:parasitology; D005260:Female; D005873:Giardiasis / Q000150:complications / Q000453:epidemiology; D006801:Humans; D008297:Male; D011204:Poverty Areas; D011446:Prospective Studies; D012307:Risk Factors; D014505:Urban Population