Computational representation of biological systems.
Integration of large and diverse biological data sets is a daunting problem facing systems biology researchers. Exploring the complex issues of data validation, integration, and representation, we present a systematic approach for the management and analysis of large biological data sets based on data warehouses. Our system has been implemented in the Bioverse, a framework combining diverse protein information from a variety of knowledge areas such as molecular interactions, pathway localization, protein structure, and protein function.
Frazier
Zach
Z
Department of Microbiology, University of Washington, Seattle, WA, USA.
McDermott
Jason
J
Guerquin
Michal
M
Samudrala
Ram
R
D000465:Algorithms; D000818:Animals; D001686:Biological Phenomena / Q000502:physiology*; D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D008954:Models, Biological; D049490:Systems Biology / Q000379:methods*