[Relationship between cystatin C and cerebral infarction].
OBJECTIVE
To study the relationship between cystatin C and cerebral infarction and explore the role of cystatin C in the protection against cerebral infarction.


METHODS
Eighty-three patients with cerebral infarction and 71 randomly selected age- and gender-matched patients in the Department of Neurology (control group) were enrolled in this study. Fasting whole blood (3 ml) was obtained from the patients in both groups and the sera were separated to determine the levels of cystatin C using particle reinforced immunoturbidimetric assay.


RESULTS
The serum cystatin C level was significantly lower in the cerebral infarction group than in the control group (1.62-/+0.31 vs 2.23-/+0.22 mg/L, P<0.01).


CONCLUSIONS
Cystatin C is closely related to cerebral infarction probably as a protective factor against cerebral infarction.
Zhao
De-qiang
DQ
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Pan
Su-yue
SY
Chen
Jian-hui
JH
Yang
Wen-jun
WJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002544:Cerebral Infarction / Q000097:blood / Q000378:metabolism*; D055316:Cystatin C / Q000097:blood / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D055316:Cystatin C