title: Paget's disease in contralateral breast occuring 11 years after mastectomy for invasive ductal carcinoma.
abstract: Paget's disease of the breast is a rare form of breast cancer and represents only 1% to 4% of all breast cancers. It is characterized by the presence of Paget's cells in the epithelium tissue (in epidermis) and it manifests as a lesion of the nipple. In most cases, Paget's disease is associated with an underlying breast malignancy. Mastectomy has been considered the treatment of choice, but breast conservation is also being explored, in properly selected patients, depending on the underlying malignancy. We report a case of Paget's disease occurring in the contralateral breast 11 years after mastectomy for invasive ductal carcinoma but with no underlying breast malignancy.
authors.affiliation: Department of Oncology and Nuclear Medicine, University Hospital "Sestre milosrdnice", Zagreb, Croatia.
authors.forename: Daniela
authors.initials: D
authors.lastname: Salopek
authors.forename: Jure
authors.initials: J
authors.lastname: Murgić
authors.forename: Davor
authors.initials: D
authors.lastname: Tomas
authors.forename: Ante
authors.initials: A
authors.lastname: Bolanca
authors.forename: Zvonko
authors.initials: Z
authors.lastname: Kusić
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000601:surgery*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008408:Mastectomy; D010144:Paget's Disease, Mammary / Q000473:pathology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human