[Frontal mass simulating lipoma as a clinical presentation of prostatic adenocarcinoma].
OBJECTIVE
To report one case of metastatic prostatic carcinoma with a gaudy presentation as a lump which resulted to be a cutaneous metastasis.


METHODS
We describe the debut in a patient, who thanks to the pathologic analysis of a lesion mimicking a lipoma, which was reported as adenocarcinoma, was worked up for prostatic adenocarcinoma and diagnosis was reached. We performed a bibliographic review using an electronic bibliographic search in PubMed (MEDLINE) using the terms "Prostatic Neoplasm" (MesH) AND "Neoplasm Metastasis" (MesH) AND "cutaneous" (free text). Most publications are case reports reviewing the probable dissemination way and localization.


RESULTS
Positive immunohistochemical staining for PSA confirmed the origin of the metastasis, although PSA value did not offer doubts due to its value over 1100 ng/ml. Regarding the bibliographic search we obtained more than 26 papers, and selected only 8 that were adjusted to the objectives of our work. Cutaneous metastasis of prostatic origin appear in less than 0.3% of the cases, because bone, lymph node, and visceral disease are more frequent. Cases appearing during the evolution of the disease and metastasis after laparoscopic procedures are described.


CONCLUSIONS
Cutaneous metastases of prostatic adenocarcinoma are very rare, but even rarer is it being the debut of the disease.
Guzman Martinez-Valls
Pablo Luis
PL
Servicio de Urología, Hospital General Universitario Morales Meseguer, Murcia, España. pabloguzman@terra.es
Rodríguez Tardido
Almudena
A
Honrubia Vilchez
Beatriz
B
Izquierdo Morejon
Emilio
E
Pietricica
Bogdan-Nicolau
BN
Montoya Chinchilla
Raúl
R
Rosino Sanchez
Antonio
A
Hita Villaplana
Gregorio
G
Romero Hoyuela
Antonio
A
Miñana Lopez
Bernardino
B
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary*; D000368:Aged; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D006801:Humans; D008067:Lipoma / Q000175:diagnosis*; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000556:secondary*