title: Organelle proteomics.
abstract: The proteome of the cell is at the frontier of being too complex for proteomic analysis. Organelles provide a step up. Organelles compartmentalize the cell enabling a proteome, physiology and metabolism analysis in time and in space. Protein complexes separated by electrophoresis have been identified as the next natural level to characterize the organelles' compartmentalized membrane and soluble proteomes by mass spectrometry. Work on mitochondria and chloroplasts has shown where we are in the characterization of complex proteomes to understand the network of endogenous and extrinsic factors which regulate growth and development, adaptation and evolution.
authors.affiliation: Department Biology I, University Munich, LMU, Menzingerstr. 67, 80638, Munich.
authors.forename: Matthias
authors.initials: M
authors.lastname: Plöscher
authors.forename: Bernhard
authors.initials: B
authors.lastname: Granvogl
authors.forename: Veronika
authors.initials: V
authors.lastname: Reisinger
authors.forename: Axel
authors.initials: A
authors.lastname: Masanek
authors.forename: Lutz Andreas
authors.initials: LA
authors.lastname: Eichacker
mesh_terms: D002736:Chloroplasts / Q000737:chemistry; D004591:Electrophoresis, Polyacrylamide Gel / Q000295:instrumentation / Q000379:methods; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods; D008928:Mitochondria / Q000737:chemistry; D015388:Organelles / Q000737:chemistry*; D020543:Proteome / Q000032:analysis*; D040901:Proteomics / Q000295:instrumentation / Q000379:methods*
chemical_list: D020543:Proteome