title: Single cell oil production by Mortierella alpina.
abstract: A filamentous fungus, Mortierella alpina 1S-4, was obtained, through extensive screening, as an potential producer of triacylglycerol containing C20 polyunsaturated fatty acids (PUFAs) such as arachidonic acid. With this discovery as a starting point, we conducted employing methods from metabolic engineering and molecular biology for controlling cultures and breeding mutant strains. These parental and mutant strains are now used for large-scale production of a variety of PUFAs.
authors.affiliation: Kyoto University, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Sakuradani
authors.forename: Sakayu
authors.initials: S
authors.lastname: Shimizu
mesh_terms: D016718:Arachidonic Acid / Q000096:biosynthesis; D005818:Genetic Engineering; D020094:Mortierella / Q000166:cytology* / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D009821:Oils / Q000378:metabolism*
chemical_list: D009821:Oils; D016718:Arachidonic Acid