Ultrasound promoted synthesis of bis(substituted pyrazol-4-ylcarbonyl)-substituted thioureas.
A series of novel bis(substituted pyrazol-4-ylcarbonyl)-substituted thioureas have been synthesized by the reactions of substituted pyrazol-4-ylcarbonyl isothiocyanates with different diamines under ultrasound irradiation and classical heating method at 20-25 degrees C. In general, substantial improvement in rates and modest yields increases were observed when reactions were carried out under sonication, compared with the classical heating method. The structures of these compounds have been elucidated by elemental and spectral (IR, (1)H-NMR) analysis.
Xiao
Li
L
School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, PR China. xiaoli56490343@163.com
Liu
Chen-Jiang
CJ
Li
Yan-Ping
YP
D006358:Hot Temperature; D015394:Molecular Structure; D011720:Pyrazoles / Q000737:chemistry*; D013890:Thiourea / Q000737:chemistry*; D014465:Ultrasonics
D011720:Pyrazoles; D013890:Thiourea