title: T-cell-derived malignant lymphoma in the boxer breed.
abstract: The boxer breed of dog is at high risk for a variety of neoplasms including lymphoma. In this observational study, tissue sections from boxer dogs with lymphoma were immunostained for T and B lymphocyte distinction, and the results compared with similar studies carried out on lymphoma tissues from temporally selected cohorts of golden retriever and rottweiler dogs. The frequency of T-cell lymphomas was significantly (P < 0.001 for all comparisons) higher in the boxers than in the rottweilers or golden retrievers. We are unaware of other reports linking immunotype of canine lymphoma with breed; whether other brachycephalic breeds of dogs have a similar preponderance of T-cell lymphoma awaits further study.
authors.affiliation: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Lurie
authors.forename: M D
authors.initials: MD
authors.lastname: Lucroy
authors.forename: S M
authors.initials: SM
authors.lastname: Griffey
authors.forename: E
authors.initials: E
authors.lastname: Simonson
authors.forename: B R
authors.initials: BR
authors.lastname: Madewell