Fibrae medullares in the retina of the RD mouse: a case report.
OBJECTIVE
A rare finding of fibrae medullares in the mouse eye is presented in an animal suffering from retinal degeneration.


METHODS
Numerous eyes from different mouse strains were screened for myelinated fibres in the retina. Light and electron microscopy was used to document a single case in a rd mouse.


RESULTS
Myelinated fibres were found in the inner retina but not continuous with the optic nerve.


CONCLUSIONS
Even in this highly degenerated retina the potency of the optic nerve fibres to become myelinated still remained. The source of the appropriate glia cells is discussed.
May
Christian Albrecht
CA
Department of Anatomy, Medical Faculty Carl Gustav Carus, Dresden, Germany.
D000818:Animals; D016570:Bruch Membrane / Q000473:pathology; D002829:Choroid / Q000473:pathology; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology*; D012162:Retinal Degeneration / Q000473:pathology*; D055213:Retinal Pigment Epithelium / Q000473:pathology