A new C-methylated homoisoflavanone and triterpenoid from the rhizomes of Polygonatum odoratum.
A new C-methylated homoisoflavanone together with four known rare methyl-homoisoflavanones and one known 9,19-cyclolart triterpenoid were isolated and characterised from the rhizomes of Polygonatum odoratum. The structure of the new compound was determined as 3-(4'-methoxy-benzyl)-5,7-dihydroxy-6-methyl-8-methoxy-chroman-4-one (1). The four known methyl-homoisoflavanones were determined as 3-(4'-methoxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one (2), 3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one (3), 3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8-methoxy-chroman-4-one (4) and 3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6-methyl-chroman-4-one (5). The one 9,19-cyclolart triterpenoid was determined as 9,19-cyclolart-25-en-3beta,24 (R)-diol (6). Compound 2, 5, 6 were isolated for the first time from the Polygonatum genus. The compounds (1,3-6) were found to be strong against the growth of bacteria and plant pathogenic fungi.
Wang
Dongmei
D
College of Forestry, Northwest Sci-Tech of Agriculture and Forestry University, Yangling, P.R. China.
Li
Dengwu
D
Zhu
Wei
W
Peng
Pai
P
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D031384:Polygonatum / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000890:Anti-Infective Agents; D007529:Isoflavones; D014315:Triterpenes