title: The obstetric face and challenge of HIV/AIDS.
abstract: The human immunodeficiency virus (HIV) pandemic is one of the most serious health crises facing the world. Of the estimated 33.2 million people living with HIV worldwide, 22.5 million (68%) live in Sub-Saharan Africa, where women of childbearing age are most severely affected. Children primarily acquire HIV infection through mother-to-child transmission. Despite recent encouraging success, low-income countries have not been able to effectively curtail transmission of HIV to the infant during or after pregnancy, resulting in about 90% of the estimated 420,000 newly infected children per annum occurring in Sub-Saharan Africa.
authors.affiliation: Department of Obstetrics and Gynaecology daggerReproductive Health and HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa. Franco.Guidozzi@wits.ac.za
authors.forename: Franco
authors.initials: F
authors.lastname: Guidozzi
authors.forename: Vivian
authors.initials: V
authors.lastname: Black
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control; D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission; D019380:Anti-HIV Agents / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage; D044966:Anti-Retroviral Agents / Q000008:administration & dosage; D023241:Antiretroviral Therapy, Highly Active; D001942:Breast Feeding; D003906:Developing Countries; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D019259:Lamivudine / Q000008:administration & dosage; D008428:Maternal Mortality; D019829:Nevirapine / Q000008:administration & dosage; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage; D014944:World Health Organization; D015215:Zidovudine / Q000008:administration & dosage
chemical_list: D019380:Anti-HIV Agents; D000890:Anti-Infective Agents; D044966:Anti-Retroviral Agents; D019259:Lamivudine; D015215:Zidovudine; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D019829:Nevirapine