title: Evidence of feline herpesvirus-1 DNA in the vestibular ganglion of domestic cats.
abstract: In humans, herpes simplex virus type-1 has recently been detected in the vestibular ganglion (VG) and labyrinth (VL) and may be associated with vestibular signs. Feline herpesvirus-1 (FHV-1) is widespread amongst cat populations and affects many different tissues. The aim of this pilot study was to investigate the presence of FHV-1 DNA in the VG and VL of randomly selected domestic cats using PCR. FHV-1 DNA was detected in the VG of 14% of the cats. There was no detectable FHV-1 DNA in the VL of any cat. None of the infected cats had vestibular signs related to the VG infection.
authors.affiliation: Chairs of General Pathology and Neuropathology, Institute of Veterinary Pathology, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Birgit
authors.initials: B
authors.lastname: Parzefall
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schmahl
authors.forename: Andrea
authors.initials: A
authors.lastname: Fischer
authors.forename: Andreas
authors.initials: A
authors.lastname: Blutke
authors.forename: Uwe
authors.initials: U
authors.lastname: Truyen
authors.forename: Kaspar
authors.initials: K
authors.lastname: Matiasek
mesh_terms: D018138:Alphaherpesvirinae / Q000235:genetics / Q000302:isolation & purification*; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000821:virology*; D002415:Cats; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D017950:Ganglia, Sensory / Q000821:virology*; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D008297:Male; D014725:Vestibular Nerve / Q000821:virology; D014722:Vestibule, Labyrinth / Q000821:virology
chemical_list: D004279:DNA, Viral