Synchronous infiltrating ductal carcinoma and primary extramedullary plasmacytoma of the breast.
BACKGROUND
Extramedullary plasmacytomas are seldom solitary and usually progress to diffuse myelomatosis. Plasmacytomas of the breast are rare, especially when not associated multiple myeloma. Synchronous infiltrating ductal carcinoma and primary extramedullary plasmacytoma of the breast have not previously reported.


METHODS
A 27-years-old woman with an untreated upper outer quadrant breast mass for 1-year was referred to our cancer hospital for surgical evaluation of increasing breast pain. Postoperatively, microscopic examination revealed an infiltrating ductal carcinoma complicated by an extramedullary plasmacytoma divided by fibrous tissue in one section. Following surgery, the patient received chemotherapy for the carcinoma and radiotherapy for the plasmacytoma.


CONCLUSIONS
In this case, careful histopathology examination was essential to make the correct diagnosis and therapy for these synchronous lesions. The patient finished chemotherapy and radiotherapy without significant adverse effects.
Cao
Shui
S
Department of Biotherapy, Tianjin Cancer Hospital & Institute, Tianjin Medical University, Tianjin, PR China. walterduke2002@yahoo.com
Kang
Hong-Gang
HG
Liu
Yan-Xue
YX
Ren
Xiu-Bao
XB
D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D010954:Plasmacytoma / Q000473:pathology* / Q000601:surgery