title: Type 2 diabetes prevention in the real world: three-year results of the GOAL lifestyle implementation trial.
abstract: OBJECTIVE We study the effectiveness of the GOAL Lifestyle Implementation Trial at the 36-month follow-up. RESEARCH DESIGN AND METHODS Participants (n = 352, type 2 diabetes risk score FINDRISC = 16.2 +/- 3.3, BMI 32.6 +/- 5.0 kg/m(2)) received six lifestyle counseling sessions over 8 months. Measurements were at baseline, 12 months (88.6%), and 36 months (77.0%). RESULTS Statistically significant risk reduction at 12 months was maintained at 36 months in weight (-1.0 +/- 5.6 kg), BMI (-0.5 +/- 2.1 kg/m(2)), and serum total cholesterol (-0.4 +/- 1.1 mmol/l). CONCLUSIONS Maintenance of risk reduction in this "real world" trial proves the intervention's potential for significant public health impact.
authors.affiliation: National Institute for Health and Welfare, Helsinki, Finland. pilvikki.absetz@thl.fi
authors.forename: Pilvikki
authors.initials: P
authors.lastname: Absetz
authors.forename: Brian
authors.initials: B
authors.lastname: Oldenburg
authors.forename: Nelli
authors.initials: N
authors.lastname: Hankonen
authors.forename: Raisa
authors.initials: R
authors.lastname: Valve
authors.forename: Heikki
authors.initials: H
authors.lastname: Heinonen
authors.forename: Aulikki
authors.initials: A
authors.lastname: Nissinen
authors.forename: Mikael
authors.initials: M
authors.lastname: Fogelholm
authors.forename: Martti
authors.initials: M
authors.lastname: Talja
authors.forename: Antti
authors.initials: A
authors.lastname: Uutela
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000517:prevention & control* / Q000523:psychology; D005500:Follow-Up Studies; D018149:Glucose Intolerance / Q000453:epidemiology; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D018570:Risk Assessment; D040242:Risk Reduction Behavior; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D002784:Cholesterol