A ligand free and room temperature protocol for Pd-catalyzed Kumada-Corriu couplings of unactivated alkenyl phosphates.
Kumada-Corriu cross-couplings of nonactivated cyclic and acyclic vinyl phosphates with aryl magnesium reagents afforded a series of 1,1-disubtituted alkenes in good yields for most cases when the reactions were performed at room temperature with the simple palladium salt, PdCl(2), without the presence of phosphine ligands.
Gauthier
Delphine
D
The Center for Insoluble Protein Structures (inSPIN), Department of Chemistry and the Interdisciplinary Nanoscience Center, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
Beckendorf
Stephan
S
Gøgsig
Thomas M
TM
Lindhardt
Anders T
AT
Skrydstrup
Troels
T
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D010165:Palladium / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D013696:Temperature
D000475:Alkenes; D008024:Ligands; D010710:Phosphates; D010165:Palladium