Crohn's disease-associated Nod2 mutants reduce IL10 transcription.
Philpott
Dana J
DJ
Girardin
Stephen E
SE
D000818:Animals; D003424:Crohn Disease / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D016753:Interleukin-10 / Q000096:biosynthesis* / Q000235:genetics; D009154:Mutation; D053473:Nod2 Signaling Adaptor Protein / Q000235:genetics*; D014158:Transcription, Genetic
C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein; D016753:Interleukin-10