title: Attentional modulation of perceived pain intensity in capsaicin-induced secondary hyperalgesia.
abstract: Perceived pain intensity is modulated by attention. However, it is not known that how pain intensity ratings are affected by attention in capsaicin-induced secondary hyperalgesia. Here we show that perceived pain intensity in secondary hyperalgesia is decreased when attention is distracted away from the painful pinprick stimulus with a visual task. Furthermore, it was found that the magnitude of attentional modulation in secondary hyperalgesia is very similar to that of capsaicin-untreated, control condition. Our findings, showing no interaction between capsaicin treatment and attentional modulation suggest that capsaicin-induced secondary hyperalgesia and attention might affect mechanical pain through independent mechanisms.
authors.affiliation: MR Research Center, Szentágothai J. Knowledge Center, Semmelweis University, Budapest, Hungary. ikobor@gmail.com
authors.forename: István
authors.initials: I
authors.lastname: Kóbor
authors.forename: Viktor
authors.initials: V
authors.lastname: Gál
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Vidnyánszky
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001288:Attention; D002211:Capsaicin / Q000633:toxicity*; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000139:chemically induced / Q000523:psychology*; D008297:Male; D009483:Neuropsychological Tests; D010146:Pain / Q000139:chemically induced / Q000523:psychology*; D010147:Pain Measurement; D010465:Perception; D010775:Photic Stimulation; D010812:Physical Stimulation; D018689:Sensory System Agents / Q000633:toxicity*; D013647:Task Performance and Analysis; D055815:Young Adult
chemical_list: D018689:Sensory System Agents; D002211:Capsaicin