title: Melanocytoma of ciliary body and choroids simulating melanoma.
abstract: Melanocytoma is a rare intraocular tumor. There are some reports in the literature dealing with primary melanocytomas of the choroid and ciliary body. It is believed that most of these tumors are clinically diagnosed as nevi or melanoma, and are followed up or treated without surgical resection, respectively. Some clinical features can give a clue as to the correct diagnosis. We report on a 47-year-old white female with progressive visual loss of 2 months and right painful eye. Her visual acuity of finger counting was confined to 3.0m OD and 20/20 OS. Biomicroscopy OD showed a 360 degrees posterior synechia, and fundoscopy was not conclusive due to vitreous opacity. No alterations were seen on OS. Intraocular pressure was normal, and the pupillary reflex was present in both eyes. An ultrasound of the OD showed an elevated tumor on topography of the ciliary body and anterior choroid at the ora serrata level. Melanoma was the main diagnosis considered, and enucleation was indicated due to poor prognosis for visual acuity. Gross and histopathologic examinations of the OD showed a heavily pigmented tumor. The brownish pigment obscured the morphology of the tumor cells that could not be visualized by conventional H&E stain. Bleached slides showed that tumor was composed of melanocytoma cells type I.
authors.affiliation: Department of Pathology, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
authors.forename: Maçanori
authors.initials: M
authors.lastname: Odashiro
authors.forename: Alexandre
authors.initials: A
authors.lastname: Odashiro
authors.forename: Lívio
authors.initials: L
authors.lastname: Leite
authors.forename: Marco
authors.initials: M
authors.lastname: Melo
authors.forename: Patrícia
authors.initials: P
authors.lastname: Odashiro
authors.forename: Luciana
authors.initials: L
authors.lastname: Miiji
authors.forename: Danilo
authors.initials: D
authors.lastname: Odashiro
authors.forename: Priscila
authors.initials: P
authors.lastname: Fernandes
authors.forename: Miguel
authors.initials: M
authors.lastname: Burnier
mesh_terms: D002830:Choroid Neoplasms / Q000473:pathology* / Q000601:surgery; D002924:Ciliary Body / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D009506:Nevus / Q000473:pathology* / Q000601:surgery; D014604:Uveal Neoplasms / Q000473:pathology* / Q000601:surgery