title: Viral gametocytic hypertrophy of the Pacific oyster Crassostrea gigas in Ireland.
abstract: Viral gametocytic hypertrophy (VGH) was detected during an investigation of mortalities in Pacific oysters Crassostrea gigas from 2 separate Irish production sites. The basophilic inclusions were observed in the gonad tissue of oysters sampled in August and October 2007. The oysters involved did not show any macroscopic disease signs. Transmission electron microscopy demonstrated the presence of viral particles in these intranuclear inclusions. The particles were small, non-enveloped, icosahedral and approximately 50 nm in diameter, and thus had characteristics similar to the Papillomaviridae and Polyomaviridae families. No host defence reaction was observed. The viral particles described here appear to be similar to those described in C. virginica from the USA and Canada and to those described in C. gigas from Korea and France.
authors.affiliation: Fish Health Unit, Marine Institute, Rinville, Oranmore, Co. Galway, Ireland.
authors.forename: Deborah
authors.initials: D
authors.lastname: Cheslett
authors.forename: Frank
authors.initials: F
authors.lastname: McKiernan
authors.forename: Cathy
authors.initials: C
authors.lastname: Hickey
authors.forename: Evelyn
authors.initials: E
authors.lastname: Collins
mesh_terms: D000818:Animals; D017756:Aquaculture; D049896:Crassostrea / Q000821:virology*; D005260:Female; D005854:Germ Cells / Q000821:virology; D006066:Gonads / Q000473:pathology / Q000821:virology; D007494:Ireland; D008297:Male; D012098:Reproduction; D014780:Viruses