Identification of a novel allele HLA-DRB1*0478 by sequence-based typing in a Chinese individual.
A novel allele HLA-DRB1*0478 is described. This variant has one nucleotide substitution in exon 2. This mutations result in an amino acid substitution at condon 70 (CAG --> CGG) from Gln to Arg.
Gao
S-Q
SQ
Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, China.
Deng
Z-H
ZH
Xu
Y-P
YP
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics*; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D002681:China; D005091:Exons / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains