[A case of locally advanced rectal cancer responding to FOLFOX].
The 57-year-old man was underwent sigmoid colostomy due to unresectable rectal carcinoma. Then he was treated with chemotherapy of levofolinate/5-fluorouracil/oxaliplatin(FOLFOX). After completion of 12 courses of chemotherapy, MR revealed responses. The patient underwent a low anterior resection. Preoperative chemotherapy with FOLFOX appears a promising regimen for patients with unresectable rectal cancer.
Kume
Shuichi
S
Department of Surgery, National Health Insurance Ueki Municipal Hospital.
Kubota
Tatsuo
T
Takahashi
Masafumi
M
Hashimoto
Daisuke
D
Hirata
Takafumi
T
Torigoe
Yoshitsugu
Y
Ikeda
Osamu
O
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D011351:Proctoscopy; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery
D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil