title: Protective effects of celery juice in treatments with Doxorubicin.
abstract: The aim of this work was to investigate possible protective effect of celery juice in doxorubicin treatment. The following biochemical parameters were determined: content of reduced glutathione, activities of catalase, xanthine oxidase, glutathione peroxidase, peroxidase, and lipid peroxidation intensity in liver homogenate and blood hemolysate. We examined influence of diluted pure celery leaves and roots juices and their combinations with doxorubicine on analyzed biochemical parameters. Celery roots and leaves juices influenced the examined biochemical parameters and showed protective effects when applied with doxorubicine.
authors.affiliation: Institute for Child and Youth Health Care of Vojvodina, Department of Hematology/Oncology, Novi Sad, Republic of Serbia. popovic@ih.ns.ac.yu
authors.forename: Jovanka
authors.initials: J
authors.lastname: Kolarovic
authors.forename: Mira
authors.initials: M
authors.lastname: Popovic
authors.forename: Momir
authors.initials: M
authors.lastname: Mikov
authors.forename: Radoslav
authors.initials: R
authors.lastname: Mitic
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Gvozdenovic
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D000077102:Apium / Q000033:anatomy & histology / Q000737:chemistry*; D001798:Blood Proteins / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D019610:Cytoprotection; D004317:Doxorubicin / Q000494:pharmacology / Q000633:toxicity; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D051379:Mice; D009195:Peroxidase / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D014969:Xanthine Oxidase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D001798:Blood Proteins; D010936:Plant Extracts; D004317:Doxorubicin; D002374:Catalase; D009195:Peroxidase; D005979:Glutathione Peroxidase; D014969:Xanthine Oxidase; D005978:Glutathione