title: Sensorineural hearing loss in patients with inflammatory bowel disease.
abstract: OBJECTIVE
  The study aimed to discuss the association between sensorineural hearing loss (SNHL) and inflammatory bowel disease (IBD).
  
  
  METHODS
  We reviewed cases of patients with known IBD seen in an otolaryngology practice with documentation of all otologic data including age of onset, family history of otologic problems, exposure to noise, audiometric findings, and so on.
  
  
  RESULTS
  Of 38 patients with a history of IBD, 22 had documented SNHL. Nineteen of these had no other identifiable etiology for their inner ear dysfunction. Fourteen of these patients had a diagnosis of ulcerative colitis and 5 had Crohn disease. Sixteen patients had bilateral SNHL, and 3 patients had unilateral SNHL. Only one patient had a lasting response of SNHL to medical treatment.
  
  
  CONCLUSIONS
  This review suggests that SNHL is an extraintestinal association of IBD. As IBD is considered to be a local or systemic immunopathy, the associated SNHL might also be an expression of systemic immune dysfunction.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA. ckarmody@tufts-nemc.org
authors.forename: Collin S
authors.initials: CS
authors.lastname: Karmody
authors.forename: Tulio A
authors.initials: TA
authors.lastname: Valdez
authors.forename: Urmen
authors.initials: U
authors.lastname: Desai
authors.forename: Nikolas H
authors.initials: NH
authors.lastname: Blevins
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001299:Audiometry; D002648:Child; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007107:Immune System / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D038781:Otoscopy; D012720:Severity of Illness Index; D055815:Young Adult