[Transglycosylation of benzo[h]quinazolines].
This was the first study to apply cyclodextrin glucanotransferases (CGTase, EC 2.4.1.19) produced by mesophilic, thermophilic, alkaliphilic, and halophilic bacilli as well as pullulanase, beta-amylase, beta-galactosidase, and beta-fructofuranosidase for transglycosylation of benzo[h]quinazolines. The combination of CGTase produced by Bacillus stearothermophilus ST-88 and gamma-cyclodextrin (CD) used as a donor of glucosyl residues was the most efficient. The derivatives obtained are water-soluble. The synthesized products have been purified by various chromatographic methods and their fine structures have been determined.
Markosian
A A
AA
Abelian
L A
LA
Markosian
A I
AI
Abelian
V A
VA
D001411:Geobacillus stearothermophilus / Q000201:enzymology*; D005964:Glucosyltransferases / Q000737:chemistry*; D006026:Glycoside Hydrolases / Q000737:chemistry*; D006031:Glycosylation; D011799:Quinazolines / Q000737:chemistry*; D047408:gamma-Cyclodextrins / Q000737:chemistry*
D011799:Quinazolines; D047408:gamma-Cyclodextrins; D005964:Glucosyltransferases; C019963:cyclomaltodextrin glucanotransferase; D006026:Glycoside Hydrolases