title: Alzheimer's disease and atherosclerosis: passers-by or brothers?
abstract: There seems to be little relationship between Alzheimer's disease and atherosclerotic disease for quite a long time. But current evidence from epidemiological, pathological, and clinical studies indicate an association of them both. We speculate that Alzheimer's disease and atherosclerosis are brothers but not passers-by, in molecule, especially in the light of interaction between reticulon 3(RTN3) and reticulon 4(RTN4B).
authors.affiliation: Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Xing
authors.forename: Shuiping
authors.initials: S
authors.lastname: Zhao
authors.forename: Rong
authors.initials: R
authors.lastname: Xiang
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism; D050197:Atherosclerosis / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D009185:Myelin Proteins / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D000070798:Nogo Proteins; D011485:Protein Binding
chemical_list: D002352:Carrier Proteins; D008565:Membrane Proteins; D009185:Myelin Proteins; D009419:Nerve Tissue Proteins; D000070798:Nogo Proteins; C476198:RTN3 protein, human; C000603199:RTN4 protein, human