title: Analysis of 60 patients after tympanotomy and sealing of the round window membrane after acute unilateral sensorineural hearing loss.
abstract: OBJECTIVE
  This retrospective study was performed to evaluate the effectiveness of tympanotomy and sealing of the round window membrane after unilateral acute hearing loss.
  
  
  METHODS
  All patients presenting idiopathic sudden hearing loss, acoustic, or barotrauma were treated with prednisolone and caroverine. Thirty-six patients had a mean pure tone hearing level worse than 70 dB. Recovery was defined as improvement of hearing threshold for 5 frequencies (250, 500, 1000, 2000, and 4000 Hz). If hearing did not improve after conservative treatment, an exploratory tympanotomy and sealing of the round window membrane were suggested. In the last 8 years, 60 patients with idiopathic sudden hearing loss, acoustic, or barotrauma underwent tympanotomy.
  
  
  RESULTS
  In 40 patients, we observed improvement of hearing level up to complete remission. In 20 patients, no change could be detected. In the group of patients with documented barotrauma, 12 patients showed improved hearing levels. Of 37 patients with idiopathic sudden hearing loss, 26 had an improved hearing after surgery. Most patients were operated on within 14 days (range, 1-60 days), but time of surgery had no influence on outcome in patients with idiopathic hearing loss. In contrast, in patients with barotrauma, time of surgery seems to have an influence on outcome.
  
  
  CONCLUSIONS
  Tympanotomy and sealing of the round window membrane can be recommended in cases of acute hearing loss after failure of conservative treatment.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Vienna, Vienna, Austria. claudia.gedlicka@meduniwien.ac.at
authors.forename: Claudia
authors.initials: C
authors.lastname: Gedlicka
authors.forename: Michael
authors.initials: M
authors.lastname: Formanek
authors.forename: Klaus
authors.initials: K
authors.lastname: Ehrenberger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001301:Audiometry, Pure-Tone; D001469:Barotrauma / Q000601:surgery; D002648:Child; D003348:Cortisone / Q000627:therapeutic use; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000628:therapy*; D003639:Hearing Loss, Sudden / Q000209:etiology / Q000628:therapy*; D046088:Hearing Loss, Unilateral / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008876:Middle Ear Ventilation; D011810:Quinoxalines / Q000627:therapeutic use; D012189:Retrospective Studies; D012405:Round Window, Ear / Q000293:injuries / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000893:Anti-Inflammatory Agents; D011810:Quinoxalines; D003348:Cortisone; C000957:caroverine