title: An optical coherence microscope for 3-dimensional imaging in developmental biology.
abstract: An optical coherence microscope (OCM) has been designed and constructed to acquire 3-dimensional images of highly scattering biological tissue. Volume-rendering software is used to enhance 3-D visualization of the data sets. Lateral resolution of the OCM is 5 mm (FWHM), and the depth resolution is 10 mm (FWHM) in tissue. The design trade-offs for a 3-D OCM are discussed, and the fundamental photon noise limitation is measured and compared with theory. A rotating 3-D image of a frog embryo is presented to illustrate the capabilities of the instrument.
authors.forename: B
authors.initials: B
authors.lastname: Hoeling
authors.forename: A
authors.initials: A
authors.lastname: Fernandez
authors.forename: R
authors.initials: R
authors.lastname: Haskell
authors.forename: E
authors.initials: E
authors.lastname: Huang
authors.forename: W
authors.initials: W
authors.lastname: Myers
authors.forename: D
authors.initials: D
authors.lastname: Petersen
authors.forename: S
authors.initials: S
authors.lastname: Ungersma
authors.forename: R
authors.initials: R
authors.lastname: Wang
authors.forename: M
authors.initials: M
authors.lastname: Williams
authors.forename: S
authors.initials: S
authors.lastname: Fraser