title: Gastrointestinal stromal tumor complicated by Streptococcus milleri bacteremia and liver abscess.
abstract: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Often discovered incidentally, GISTs can present with nonspecific abdominal symptoms or more overt symptoms of bleeding, obstruction, or perforation. Despite a myriad of clinical presentations, bacteremia associated with a GIST has not been described. In this report, we present an unusual clinical case that illustrates how GISTs can become infected, and demonstrate the importance of Streptococcus milleri bacteremia as an indicator of possible underlying gastrointestinal neoplasm.
authors.affiliation: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA. yongkwon@umich.edu
authors.forename: Yong
authors.initials: Y
authors.lastname: Kwon
authors.forename: Ngoc-Duyen T
authors.initials: ND
authors.lastname: Dang
authors.forename: Badih Joseph
authors.initials: BJ
authors.lastname: Elmunzer
mesh_terms: D000328:Adult; D016470:Bacteremia / Q000382:microbiology*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000382:microbiology*; D046152:Gastrointestinal Stromal Tumors / Q000382:microbiology*; D006801:Humans; D008100:Liver Abscess / Q000382:microbiology*; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics; D013290:Streptococcal Infections / Q000382:microbiology*; D034364:Streptococcus milleri Group / Q000235:genetics; D016896:Treatment Outcome
chemical_list: D019009:Proto-Oncogene Proteins c-kit