title: [A successfully resected case of rectal cancer with liver metastases treated with mFOLFOX6 and bevacizumab].
abstract: A sixties-man had complained of melena. Colonoscopy revealed type 2 tumor at rectum. Computed tomography (CT)demonstrated lymph node metastasis in front of sacrum and two low density areas which were suspected metastases in the liver. The patient was diagnosed stageIV rectal cancer and resected primary focus and lymph node metastasis.[ Ra-RS, ant, type 2, moderately differentiated adenocarcinoma, ly1, v3, pSE, pN2, sH1(Grade C), sP0, pM1(No. 270)]without liver resection. It was due to high level of CEA and remote lymph node metastasis. The patient was treated with mFOLFOX6 and bevacizumab after the operation. The level of CEA decreased to normal level and CT revealed a partial response after 4 cycles of systemic chemotherapy. Liver resection was performed safely. Histological response was Grade 2 at liver metastases.
authors.affiliation: Department of Surgery, Hyogo Cancer Center.
authors.forename: Toshitada
authors.initials: T
authors.lastname: Fujita
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ohno
authors.forename: Shingo
authors.initials: S
authors.lastname: Kanaji
authors.forename: Iwao
authors.initials: I
authors.lastname: Kobayashi
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Ueno
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tsuchida
authors.forename: Masato
authors.initials: M
authors.lastname: Osawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujino
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kanbara
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology* / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab; D002272:Carcinoembryonic Antigen / Q000097:blood; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D002272:Carcinoembryonic Antigen; D009944:Organoplatinum Compounds; D000068258:Bevacizumab; D002955:Leucovorin; D005472:Fluorouracil