title: A patient with intractable posthypoxic myoclonus (Lance-Adams syndrome) treated with sodium oxybate.
abstract: Posthypoxic myoclonus is a rare and devastating complication of near-fatal cardiopulmonary arrest. Despite treatment with available anti-myoclonic agents, some patients may recover cognitively but remain completely disabled by severe myoclonus. We report a 16-year-old patient with severe treatment-refractory posthypoxic myoclonus, which improved markedly with administration of the drug sodium oxybate.
authors.affiliation: Department of Intensive Care and Emergency Unit, Ospedale Civile, Voghera, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Arpesella
authors.forename: C
authors.initials: C
authors.lastname: Dallocchio
authors.forename: C
authors.initials: C
authors.lastname: Arbasino
authors.forename: R
authors.initials: R
authors.lastname: Imberti
authors.forename: R
authors.initials: R
authors.lastname: Martinotti
authors.forename: S J
authors.initials: SJ
authors.lastname: Frucht
mesh_terms: D000293:Adolescent; D004569:Electroencephalography; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications*; D008297:Male; D009207:Myoclonus / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012978:Sodium Oxybate / Q000627:therapeutic use*; D013577:Syndrome
chemical_list: D012978:Sodium Oxybate