Design, synthesis and pharmacological characterization of fluorescein-derived endothelin antagonists Bq-123 and Bq-788.
Brosseau
Jean-Philippe
JP
Laboratoire de Génomique Fonctionnelle de l'Université de Sherbrooke, Centre de développement des biotechnologies (CDB) de Sherbrooke, Sherbrooke J1E 4K8, Canada.
Neugebauer
Witold A
WA
Gobeil
Fernand
F
D'Orléans-Juste
Pedro
P
D000595:Amino Acid Sequence; D000818:Animals; D015195:Drug Design; D019332:Endothelin-1 / Q000037:antagonists & inhibitors*; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011817:Rabbits
D019332:Endothelin-1; D009842:Oligopeptides; D010456:Peptides, Cyclic; D010880:Piperidines; C086539:BQ 788; C072247:cyclo(Trp-Asp-Pro-Val-Leu)