Skin spicules: A newly described paraneoplastic phenomenon associated with a marginal zone B-cell lymphoma.
Paraneoplastic signs are an important clue to diagnosing an associated malignancy. We report an unusual variant of the sign of Leser-Trélat in a patient with a low-grade B-cell lymphoproliferative disorder and intertriginous skin spicules with histologic morphology of minute seborrheic keratoses.
Hu
Stephanie
S
Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Granter
Scott R
SR
Haynes
Harley A
HA
Miller
Danielle M
DM
D000328:Adult; D006801:Humans; D017492:Keratosis, Seborrheic / Q000209:etiology / Q000473:pathology*; D016393:Lymphoma, B-Cell / Q000473:pathology*; D008297:Male; D010257:Paraneoplastic Syndromes / Q000473:pathology*; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology*