Palladium-catalyzed decarboxylative coupling of allylic alkynoates with arynes.
A novel and selective protocol for the synthesis of 1-allyl-2-ethynylbenzenes has been developed by palladium-catalyzed decarboxylative coupling of allylic alkynoates with arynes. This new route allows for both sp-sp(2) and sp(2)-sp(3) couplings of allylic alkynoates with arynes in one pot involving a decarboxylation process.
Pi
Shao-Feng
SF
Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha 410081, China.
Tang
Bo-Xiao
BX
Li
Jin-Heng
JH
Liu
Yi-Lin
YL
Liang
Yun
Y
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003653:Decarboxylation; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D000480:Alkynes; D000498:Allyl Compounds; D001555:Benzene Derivatives; D010165:Palladium