title: The superiority of 3D-CISS sequence in displaying the cisternal segment of facial, vestibulocochlear nerves and their abnormal changes.
abstract: OBJECTIVE
  To select the best imaging method for clinical otologic patients through evaluating 3D constructive interference of steady state (CISS) image quality in visualizing the facial, vestibulocochlear nerves (CN:VII-VIII) and their abnormal changes.
  
  
  METHODS
  The CN:VII-VIII as well as inner ear structures in 48 volunteers were examined using 3D-CISS and 3D turbo spin echo (TSE) sequences respectively, and displayed to the full at the reformatted and maximum intensity projection (MIP) images. The nerve identification and image quality were graded for the CN:VII-VIII as well as inner ear structures. Statistical analysis was performed using the Wilcoxin test, p<0.05 was considered significant. In addition, 8 patients with abnormality in facial or vestibulocochlear nerves were also examined using 3D-CISS sequence.
  
  
  RESULTS
  The identification rates for the cisternal segment of facial, vestibulocochlear nerves and corresponding membranous labyrinth were 100%. Abnormal changes of the facial or vestibulocochlear nerves were clearly shown in 8 patients, among them 1 was caused by bilateral acoustic neurinoma, 1 by cholesteatoma at cerebellopontine angle, 1 by arachnoid cyst, 1 by neurovascular adhesion, 4 by neurovascular compression.
  
  
  CONCLUSIONS
  With 3D-CISS sequence the fine structure of the CN:VII-VIII and corresponding membranous labyrinth can be clearly demonstrated; lesions at the site of cerebellopontine angle can also be found easily.
authors.affiliation: Shandong University, Shandong Medical Imaging Research Institute, CT Room, 324, Jingwu Road, Jinan, Shandong, PR China. tigerlch@163.com
authors.forename: Changhu
authors.initials: C
authors.lastname: Liang
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Lebin
authors.initials: L
authors.lastname: Wu
authors.forename: Yinglin
authors.initials: Y
authors.lastname: Du
authors.forename: Ximing
authors.initials: X
authors.lastname: Wang
authors.forename: Cheng
authors.initials: C
authors.lastname: Liu
authors.forename: Fuhua
authors.initials: F
authors.lastname: Yu
mesh_terms: D000328:Adult; D000368:Aged; D005154:Facial Nerve / Q000473:pathology*; D005155:Facial Nerve Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D000159:Vestibulocochlear Nerve / Q000473:pathology*; D000160:Vestibulocochlear Nerve Diseases / Q000473:pathology*