title: Regioselective and sequential reactivity of activated 2,5-diketopiperazines.
abstract: The electrophilic reactivity of Boc-DKPs has been studied. Thanks to Boc activation, the opening ability of carbonyl lactam groups is enhanced. According to experimental conditions, this enabled the synthesis of Boc-amino acid derivatives or original dipeptides via a regioselective and sequential way.
authors.affiliation: Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-Université Montpellier 1-Université Montpellier 2, Bâtiment Chimie (17), Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: Farran
authors.forename: Delphine
authors.initials: D
authors.lastname: Echalier
authors.forename: Jean
authors.initials: J
authors.lastname: Martinez
authors.forename: Georges
authors.initials: G
authors.lastname: Dewynter
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry; D054659:Diketopiperazines / Q000737:chemistry*; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D054659:Diketopiperazines; D004151:Dipeptides