title: Plasmodium vivax malaria presenting with severe thrombocytopenia, cerebral complications and hydrocephalus.
abstract: Two cases of a one and 4 year old child of plasmodium vivax malaria are reported in association with CNS complications. Both presented with encephalopathy and seizures. One had severe thrombocytopenia, massive intracranial bleed and hydrocephalus requiring shunt surgery while the other had gastrointestinal manifestations, encephalopathy and hydrocephalus. Both responded to quinine but are left with sequelae.
authors.affiliation: Department of Pediatrics, Government Medical College, Jammu, India.
authors.forename: Rekha
authors.initials: R
authors.lastname: Harish
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Gupta
mesh_terms: D000962:Antimalarials / Q000627:therapeutic use; D020808:Central Nervous System Protozoal Infections / Q000175:diagnosis* / Q000628:therapy; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000601:surgery; D007223:Infant; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D017713:Platelet Transfusion / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000628:therapy; D017287:Ventriculoperitoneal Shunt / Q000379:methods
chemical_list: D000962:Antimalarials