title: [Variations in health-related quality of life in critical patients].
abstract: OBJECTIVE
  To determine the changes in the health-related quality of life (hRQOL) six months after discharge from the ICU and the conditions associated to them.
  
  
  METHODS
  A prospective cohort study.
  
  
  METHODS
  14 beds medical-surgical intensive care unit (ICU).
  
  
  METHODS
  A total of 247 patients admitted to our ICU for more than 24 hours with a follow-up of 6 months were study. Those admitted with acute coronary syndrome or for monitoring purposes were excluded.
  
  
  METHODS
  A quality of life survey was conducted using the score developed by the PAEEC group (project of the epidemiological analysis of critical illness) to assess hRQOL before ICU admission and 6 months after discharge.
  
  
  RESULTS
  The hRQOL deteriorated, going from a median value of 3 to 6 (p < 0.001). The multivariate analysis showed less deterioration of hRQOL in patients with chronic health conditions registered on the APAChE-II score (regression coefficient [RC] = -1.4; 95% CI, -2.5 to -0.2; p < 0.02) and in those with a hRQOL > or = 10 points (RC = -4,4; 95% CI, -5.9 to -2.8; p < 0.001). There was more deterioration in polytraumatized patients (RC = 1.9; 95% CI, 0.6-3.3; p = 0.01) or with renal failure (RC = 3.9; 95% CI, 1.9-5.9; p < 0.001) or in those with a stay duration longer than 10 days (RC = 1.9; 95% CI, 0.6-3.2; p < 0.001).
  
  
  CONCLUSIONS
  Most patients experience deterioration of hRQOL. Patients with chronic diseases or with worst previous hRQOL who survive 6 months experience less deterioration of hRQOL than those who are polytraumatized or have renal failure or a longer ICU stay.
authors.affiliation: Unidad de Medicina Intensiva. Hospital Txagorritxu. Vitoria. Alava. España. SEBASTIAN.IRIBARRENDIARASARRI@osakidetza.net
authors.forename: S
authors.initials: S
authors.lastname: Iribarren-Diarasarri
authors.forename: F
authors.initials: F
authors.lastname: Aizpuru-Barandiaran
authors.forename: T
authors.initials: T
authors.lastname: Muñoz-Martínez
authors.forename: J L
authors.initials: JL
authors.lastname: Dudagoitia-Otaolea
authors.forename: A
authors.initials: A
authors.lastname: Castañeda-Sáez
authors.forename: M
authors.initials: M
authors.lastname: Hernández-López
authors.forename: S
authors.initials: S
authors.lastname: Martínez-Alutiz
authors.forename: C
authors.initials: C
authors.lastname: Vinuesa-Lozano
authors.forename: N
authors.initials: N
authors.lastname: Aretxabala-Kortajarena
mesh_terms: D016638:Critical Illness; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors