title: [Effect of a synthetic analogue of bacterial anabiosis autoinducers hexylresorcinol on the stability of membrane structures].
abstract: The effect of hexylresorcinol (HR), a chemical analogue of microbial anabiosis autoinducers of the alkylhydroxybenzene (AHB) group, on the stability of biological membranes and monolamellar liposomes formed of egg phosphatidylcholine (ePC) was studied. According to spectrophotometry and electron microscopy studying of HR-loaded liposomes in the presence of a surface-active agent Tween 20, the critical ratio between HR and ePC for liposome preservation was found to be close to equimolar. The trends in HR influence on membrane structural organization and stability confirmed in experiments on liposomes were also reproduced on intact bacterial cells explaining non-species-specific effect of AHBs. The demonstrated high efficiency of AHB biocides may be used in material and equipment protection against biocorrosion.
authors.forename: N G
authors.initials: NG
authors.lastname: Loĭlo
authors.forename: A L
authors.initials: AL
authors.lastname: Muliukin
authors.forename: A N
authors.initials: AN
authors.lastname: Kozlova
authors.forename: A P
authors.initials: AP
authors.lastname: Kaplun
authors.forename: V V
authors.initials: VV
authors.lastname: Sorokin
authors.forename: I A
authors.initials: IA
authors.lastname: Borzenkov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Nikolaev
authors.forename: A S
authors.initials: AS
authors.lastname: Kaprel'iants
authors.forename: G I
authors.initials: GI
authors.lastname: El'-Registan
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000254:growth & development*; D006604:Hexylresorcinol / Q000737:chemistry* / Q000494:pharmacology; D010713:Phosphatidylcholines / Q000737:chemistry / Q000494:pharmacology; D011136:Polysorbates / Q000737:chemistry / Q000494:pharmacology; D013501:Surface-Active Agents / Q000737:chemistry / Q000494:pharmacology; D053835:Unilamellar Liposomes / Q000737:chemistry* / Q000494:pharmacology; D015003:Yeasts / Q000254:growth & development*
chemical_list: D000890:Anti-Infective Agents; D010713:Phosphatidylcholines; D011136:Polysorbates; D013501:Surface-Active Agents; D053835:Unilamellar Liposomes; D006604:Hexylresorcinol