Pregnancy outcome after treatment of cervical intraepithelial neoplasia by the loop electrosurgical excision procedure and cold knife conization.
OBJECTIVE
The aim of this study was to evaluate the effect of LEEP and cold-knife conization on the outcome of subsequent pregnancy in a tertiary public hospital.


METHODS
One hundred and ninety-nine patients met the inclusion criteria (age between 18 and 45 years old). Cold-knife conization, LEEP, and both (conization and LEEP) were performed in 102 (51.3%), 95 (47.7%) and two (1%) women, respectively. Average ages were respectively, 33 +/- 7.3; 25 +/- 6.73 and 30 +/- 2.8.


RESULTS
Pregnancies occurred 2.6 and 4.8 years after LEEP and conization, respectively. Miscarriages and preterm pregnancies were more frequent in conization cases versus LEEP, 26% and 5.2%, 23% and 5.5%, respectively.


CONCLUSIONS
If patients express a desire for pregnancy, LEEP should be the procedure of choice.
Michelin
M A
MA
Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil.
Merino
L M
LM
Franco
C A
CA
Murta
E F C
EF
D000022:Abortion, Spontaneous / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D019092:Conization / Q000009:adverse effects*; D004598:Electrosurgery / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D047929:Term Birth; D002583:Uterine Cervical Neoplasms / Q000601:surgery; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000601:surgery