title: Asymmetric Synthesis of (+)-Iso-6-Cassine via Stereoselective Intramolecular Amidomercuration.
abstract: The first asymmetric synthesis of (+)-iso-6-cassine is described. Lipase-catalyzed resolution, enantioselective Overman rearrangement, and diastereoselective intramolecular amidomercuration were used for the installation of the three stereocenters in (+)-iso-6-cassine, and cross-metathesis was employed for the attachment of the side-chain.
authors.affiliation: Department of Chemisry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
authors.forename: Satwinder
authors.initials: S
authors.lastname: Singh
authors.forename: Om V
authors.initials: OV
authors.lastname: Singh
authors.forename: Hyunsoo
authors.initials: H
authors.lastname: Han