[Thyroid-stimulating hormone receptor antibodies in the diagnosis of Graves' disease in children].
The informative value of a method for determining total antibodies (Ab) to thyroid-stimulating hormone receptor (TSHR) in the diagnosis of Graves' disease was evaluated in 80 children with various causes of hyperthyroidism. With a RSHR Ab of > 1.6 IU/l, the diagnostic sensitivity and specificity of the test were 100%. Patients with hyperthyroidism and no RSHR Ab require no active therapeutic intervention and need to be followed up.
Savel'ev
L I
LI
Kiiaev
A V
AV
Tsvirenko
S V
SV
Gerasimova
L Iu
LIu
D000293:Adolescent; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D005260:Female; D006111:Graves Disease / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000276:immunology; D008297:Male; D011989:Receptors, Thyrotropin / Q000276:immunology*
D001323:Autoantibodies; D011989:Receptors, Thyrotropin