2009 Edward E Smissman Award. Pharmaceutical "gold" from neurostabilizing agents: topiramate and successor molecules.
Maryanoff
Bruce E
BE
Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477-0776, USA. bmaryano@its.jnj.com
D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis / Q000627:therapeutic use; D002626:Chemistry, Pharmaceutical / Q000266:history; D005632:Fructose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000627:therapeutic use; D006597:Fructose-Bisphosphatase / Q000037:antagonists & inhibitors; D049673:History, 20th Century; D006801:Humans; D007004:Hypoglycemic Agents / Q000138:chemical synthesis; D018696:Neuroprotective Agents / Q000138:chemical synthesis / Q000627:therapeutic use; D000077236:Topiramate
D000927:Anticonvulsants; D007004:Hypoglycemic Agents; D018696:Neuroprotective Agents; D000077236:Topiramate; D005632:Fructose; D006597:Fructose-Bisphosphatase