Type 2 diabetes prevention in the real world: three-year results of the GOAL lifestyle implementation trial.
OBJECTIVE We study the effectiveness of the GOAL Lifestyle Implementation Trial at the 36-month follow-up. RESEARCH DESIGN AND METHODS Participants (n = 352, type 2 diabetes risk score FINDRISC = 16.2 +/- 3.3, BMI 32.6 +/- 5.0 kg/m(2)) received six lifestyle counseling sessions over 8 months. Measurements were at baseline, 12 months (88.6%), and 36 months (77.0%). RESULTS Statistically significant risk reduction at 12 months was maintained at 36 months in weight (-1.0 +/- 5.6 kg), BMI (-0.5 +/- 2.1 kg/m(2)), and serum total cholesterol (-0.4 +/- 1.1 mmol/l). CONCLUSIONS Maintenance of risk reduction in this "real world" trial proves the intervention's potential for significant public health impact.
Absetz
Pilvikki
P
National Institute for Health and Welfare, Helsinki, Finland. pilvikki.absetz@thl.fi
Oldenburg
Brian
B
Hankonen
Nelli
N
Valve
Raisa
R
Heinonen
Heikki
H
Nissinen
Aulikki
A
Fogelholm
Mikael
M
Talja
Martti
M
Uutela
Antti
A
D000368:Aged; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000517:prevention & control* / Q000523:psychology; D005500:Follow-Up Studies; D018149:Glucose Intolerance / Q000453:epidemiology; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D018570:Risk Assessment; D040242:Risk Reduction Behavior; D015431:Weight Loss
D001786:Blood Glucose; D002784:Cholesterol