title: Postoperative pain management techniques in hip and knee arthroplasty.
abstract: Adequate control of postoperative pain following hip and knee arthroplasty can be a challenging task fraught with potential complications. Postoperative pain is perceived by the patient via a complex network and a multitude of molecular messengers in both the peripheral and central nervous systems. This allows the physician to modulate pain via an array of medications that act on different sites within the body. Using both contemporary and traditional pain modulators, the delivery and timing of these medications can affect postoperative pain and, ultimately, rehabilitation of the arthroplasty patient. Current techniques for controlling pain use both multimodal and preemptive analgesia to improve the outcome of the surgery while minimizing the potential adverse effects of the medications given.
authors.affiliation: Rothman Institute of Orthopedics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
authors.forename: Javad
authors.initials: J
authors.lastname: Parvizi
authors.forename: Manny
authors.initials: M
authors.lastname: Porat
authors.forename: Kishor
authors.initials: K
authors.lastname: Gandhi
authors.forename: Eugene R
authors.initials: ER
authors.lastname: Viscusi
authors.forename: Richard H
authors.initials: RH
authors.lastname: Rothman
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy* / Q000517:prevention & control*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors