title: ACTH therapy in refractory generalized epilepsy.
abstract: Adrenocorticotropic hormone (ACTH) has a long track record for the treatment of infantile spasms. However, there is paucity of data on the use of ACTH in the treatment of epilepsy beyond infantile spasms. We report the use of ACTH in two children with refractory generalized epilepsy. Both patients responded well. ACTH may be considered as a useful adjunctive therapy in patients with intractable generalized seizures. Side effects and cost however, remain important concerns.
authors.affiliation: Division of Child Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Veena
authors.initials: V
authors.lastname: Kalra
authors.forename: Suvasini
authors.initials: S
authors.lastname: Sharma
authors.forename: Ravindra
authors.initials: R
authors.lastname: Arya
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male
chemical_list: D000324:Adrenocorticotropic Hormone