Administration regimens for sublingual immunotherapy to pollen allergens: what do we know?
The modalities of administration of sublingual immunotherapy (SLIT), including dosing, build-up phase, duration of the treatment, and frequency of the maintenance dose are largely variable. In the case of pollen (SLIT), the complexity increases, since preseasonal, coseasonal and pre-coseasonal regimens can be used. The administration regimens are of relevance from a practical point of view, but can also have economic implications. We review herein the available literature (randomized double blind controlled studies) on pollen SLIT, in order to derive experimentally-supported suggestions about the regimens of administration that should be preferred.
Lombardi
C
C
Pneumoallergology Unit, S. Orsola FBF Hospital, Brescia, Italy.
Incorvaia
C
C
Braga
M
M
Senna
G
G
Canonica
G W
GW
Passalacqua
G
G
D000286:Administration, Sublingual; D000485:Allergens / Q000008:administration & dosage* / Q000276:immunology; D003888:Desensitization, Immunologic / Q000379:methods*; D006801:Humans; D011058:Pollen / Q000276:immunology*
D000485:Allergens