title: [Concurrent chemoradiation experience of the local relapse of rectal cancer patients].
abstract: We have reported the concurrent chemoradiation experience of local relapse of rectal cancer patients. From October 2004 to January 2007 we have treated consecutive 10 patients with radiation and the concurrent chemotherapy by CPT-11+S-1. Of 10 lesions, 5(50%)had a complete response, 2(20%)a partial response, 3(30%)a stable disease, yielding an overall response rate of 70%. Three year survival and relapse free survival was 64% and 22 months, respectively. Four patients live without cancers, 3 patients died with cancers and 2 patients live with cancers. Three patients had acute complication(more than Grade 2)including 3 appetite losses. The concurrent chemoradiation is feasible for out-patients and seems to offer good results for the local relapse of rectal cancer patients.
authors.affiliation: Department of Radiology, Hiroshima Asa City Hospital.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Akagi
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Okabe
authors.forename: Yasutoshi
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Katsuhide
authors.initials: K
authors.lastname: Ito
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002272:Carcinoembryonic Antigen / Q000097:blood; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012004:Rectal Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D002272:Carcinoembryonic Antigen