Platinum(II)-catalyzed intramolecular cyclization of o-substituted aryl alkynes through sp3 C-H activation.
Ring leader: PtCl(2) catalyzes intramolecular cyclization of o-isopropyl or o-benzyl aryl alkynes to give substituted indene derivatives with good yields and high selectivity. This reaction appears to proceed through an sp(3) C-H activation and 1,4-hydrogen migration pathway (see scheme).
Yang
Shangdong
S
Department of Chemistry, University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.
Li
Zigang
Z
Jian
Xing
X
He
Chuan
C
D000480:Alkynes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006859:Hydrogen / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis*; D010984:Platinum / Q000737:chemistry*
D000480:Alkynes; D007192:Indenes; D010984:Platinum; D002244:Carbon; D006859:Hydrogen