title: Innovations and challenges in renal cancer: summary statement from the Third Cambridge Conference.
abstract: The Third Cambridge Conference on Innovations and Challenges in Renal Cancer, a symposium held in Cambridge, Massachusetts, June 27-28, 2008, and chaired by Michael B. Atkins, was convened to discuss the current state of knowledge in the field, critique new data, stimulate communication among those involved in basic and clinical research, and offer recommendations for further study. Four main topics were discussed: genetics and molecular biology of renal cell cancer, staging and prognosis, systemic therapy, and correlative science and biomarkers in stage IV disease. The conference format combined brief presentations with extended periods of discussion. The conclusions and recommendations are summarized in this paper and presented in more detail in the individual papers that follow.
authors.affiliation: Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. matkins@bidmc.harvard.edu
authors.forename: Michael B
authors.initials: MB
authors.lastname: Atkins
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Bukowski
authors.forename: Bernard J
authors.initials: BJ
authors.lastname: Escudier
authors.forename: Robert A
authors.initials: RA
authors.lastname: Figlin
authors.forename: Gary H
authors.initials: GH
authors.lastname: Hudes
authors.forename: William G
authors.initials: WG
authors.lastname: Kaelin
authors.forename: W Marston
authors.initials: WM
authors.lastname: Linehan
authors.forename: David F
authors.initials: DF
authors.lastname: McDermott
authors.forename: James W
authors.initials: JW
authors.lastname: Mier
authors.forename: Ivan
authors.initials: I
authors.lastname: Pedrosa
authors.forename: Brian I
authors.initials: BI
authors.lastname: Rini
authors.forename: Sabina
authors.initials: S
authors.lastname: Signoretti
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Sosman
authors.forename: Bin Tean
authors.initials: BT
authors.lastname: Teh
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Wood
authors.forename: Amado J
authors.initials: AJ
authors.lastname: Zurita
authors.forename: Laura
authors.initials: L
authors.lastname: King
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D005544:Forecasting; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor