Catalytic asymmetric synthesis of cyclic alpha-alkyl-amino acid derivatives having a tetrasubstituted alpha-carbon.
Catalytic asymmetric synthesis of various cyclic alpha-alkyl-amino acid derivatives having a tetrasubstituted alpha-carbon has been accomplished by the utilization of phase-transfer alkylation of alpha-alkyl-amino acid derivatives.
Wang
Yong-Gang
YG
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, Japan.
Mii
Haruka
H
Kano
Taichi
T
Maruoka
Keiji
K
D000478:Alkylation; D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D013237:Stereoisomerism
D000596:Amino Acids; D002244:Carbon