Fin regeneration from tail segment with musculature, endoskeleton, and scales.
It is well known that fish caudal fins can be completely regenerated after fin amputation. Although much research on fin regeneration has been carried out, there have been very few reports regarding fin regeneration after tail amputation. In this study, we used grass carp, common carp, koi carp, and zebrafish as experimental organisms. Some caudal fins could be distinctly regenerated in 2 weeks after tail amputation. After all-trans-retinoic acid treatment and tail amputation, zebrafish were unable to regenerate caudal fins that could be seen with the naked eye. However, after tail amputation, more than half of the zebrafish tested were able to regenerate caudal fins. Caudal fin regeneration depended on the presence of musculature and endoskeleton at the site of amputation. These caudal fins arose from segments of the endoskeleton, which contrast with currently accepted knowledge.
Shao
Jinhui
J
Department of Anatomy, Histology and Embryology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, P. R. China.
Qian
Xiaojing
X
Zhang
Chengxia
C
Xu
Zenglu
Z
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000502:physiology; D002347:Carps; D003530:Cyprinidae / Q000502:physiology*; D004817:Epidermis / Q000187:drug effects / Q000502:physiology; D005121:Extremities / Q000033:anatomy & histology / Q000502:physiology* / Q000601:surgery; D007641:Keratolytic Agents / Q000494:pharmacology; D009024:Morphogenesis / Q000187:drug effects / Q000502:physiology; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D014212:Tretinoin / Q000494:pharmacology; D015027:Zebrafish
D007641:Keratolytic Agents; D014212:Tretinoin