title: Comparative study of the changes in partial pressure of plasma carbon dioxide during carbon dioxide insufflation into the intraperitoneal and preperitoneal spaces.
abstract: BACKGROUND
  We aimed to compare plasma concentrations of carbon dioxide (CO(2)) in dogs that underwent intra- and preperitoneal CO(2) insufflation.
  
  
  METHODS
  Thirty dogs were studied. Ten formed a control group, 10 underwent intraperitoneal CO(2) insufflation, and 10 underwent preperitoneal CO(2) insufflation. General anesthesia with controlled ventilation was standardized for all dogs. After stabilizing the anesthesia, blood samples were collected at predetermined times and were sent for immediate gasometric analysis. Analysis of variance was used for comparing variables.
  
  
  RESULTS
  The plasma CO(2) concentration in the intraperitoneal insufflation group increased significantly more than in the preperitoneal insufflation group and was significantly greater than in the control group (P < 0.05). The pH values in the intraperitoneal group were lower than in the preperitoneal group (P < 0.05).
  
  
  CONCLUSIONS
  The data from this study suggest that a greater plasma concentration of CO(2) is achieved by insufflation at constant pressure into the intraperitoneal space than into the preperitoneal space.
authors.affiliation: Department of Surgery, Heliópolis Hospital, São Paulo, Brazil. cassiojmb@ig.com.br
authors.forename: Càssio J M
authors.initials: CJ
authors.lastname: de Barros
authors.forename: Josias A
authors.initials: JA
authors.lastname: Sobrinho
authors.forename: Abrão
authors.initials: A
authors.lastname: Rapoport
authors.forename: Neil F
authors.initials: NF
authors.lastname: Novo
authors.forename: João L M C
authors.initials: JL
authors.lastname: Azevedo
authors.forename: Albino
authors.initials: A
authors.lastname: Sorbello
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood*; D004285:Dogs; D010535:Laparoscopy; D010313:Partial Pressure; D011028:Pneumoperitoneum, Artificial / Q000379:methods*; D011897:Random Allocation
chemical_list: D002245:Carbon Dioxide