title: [Thyroid-stimulating hormone receptor antibodies in the diagnosis of Graves' disease in children].
abstract: The informative value of a method for determining total antibodies (Ab) to thyroid-stimulating hormone receptor (TSHR) in the diagnosis of Graves' disease was evaluated in 80 children with various causes of hyperthyroidism. With a RSHR Ab of > 1.6 IU/l, the diagnostic sensitivity and specificity of the test were 100%. Patients with hyperthyroidism and no RSHR Ab require no active therapeutic intervention and need to be followed up.
authors.forename: L I
authors.initials: LI
authors.lastname: Savel'ev
authors.forename: A V
authors.initials: AV
authors.lastname: Kiiaev
authors.forename: S V
authors.initials: SV
authors.lastname: Tsvirenko
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Gerasimova
mesh_terms: D000293:Adolescent; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D005260:Female; D006111:Graves Disease / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000276:immunology; D008297:Male; D011989:Receptors, Thyrotropin / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D011989:Receptors, Thyrotropin