In situ enamine activation in aqueous salt solutions: highly efficient asymmetric organocatalytic Diels-Alder reaction of cyclohexenones with nitroolefins.
Deep-sea Diels-Alder: The asymmetric organocatalytic Diels-Alder reaction of cyclohexenones with aromatic nitroolefins can be carried out in seawater and brine. The reaction proceeds by an in situ enamine activation involving a one-step concerted addition pathway (see scheme).
Xu
Dan-Qian
DQ
State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou, China.
Xia
Ai-Bao
AB
Luo
Shu-Ping
SP
Tang
Jie
J
Zhang
Shuai
S
Jiang
Jun-Rong
JR
Xu
Zhen-Yuan
ZY