title: Biomechanical modeling of decompressive craniectomy in traumatic brain injury.
abstract: BACKGROUND
  Decompressive craniectomy is the final phase in the graded scheme of critical care management of refractory raised intracranial pressure following severe traumatic brain injury. We aim to define the optimal size for decompressive craniectomy so that a good balance is achieved between reduction of raised ICP and the extent of trans-calvarial herniation. Provision of such quantitative data will also allow for improved data comparison in clinical trials addressing the surgical management of severe head injury.
  
  
  METHODS
  In this study, we utilize a finite element mesh model and focus on the effect of size of both unilateral and bifrontal decompressive craniectomy on intracranial pressure and brain herniation.
  
  
  RESULTS
  The finite element mesh model is able to effect modeling of brain deformation and intracranial pressure changes following both unilateral fronto-parietal-temporal and bifrontal decompressive craniectomy.
  
  
  CONCLUSIONS
  Finite element mesh modeling in the scenario of reafractory raised intracranial pressure following severe head injury may be able to guide the optimal conduct of decompressive surgery so as to effect a reduction in intracranial pressure whilst minimizing trans-calvarial brain herniation.
authors.affiliation: Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Tan Tock Seng, Singapore 308433.
authors.forename: Chun Ping
authors.initials: CP
authors.lastname: Gao
authors.forename: Beng Ti
authors.initials: BT
authors.lastname: Ang
mesh_terms: D001696:Biomechanical Phenomena; D001929:Brain Edema / Q000209:etiology / Q000601:surgery*; D001930:Brain Injuries / Q000150:complications; D003198:Computer Simulation; D003399:Craniotomy / Q000379:methods*; D019299:Decompression, Surgical / Q000379:methods*; D006801:Humans; D019586:Intracranial Hypertension / Q000209:etiology / Q000601:surgery*; D007427:Intracranial Pressure / Q000502:physiology; D008954:Models, Biological; D009460:Neurologic Examination; D016896:Treatment Outcome