title: Perivascular epithelioid tumor (PEComa) of the falciform/ broad ligament.
abstract: PEComas localized in the region of falciform ligament and broad ligament are exceedingly rare. Most of them are built of spindle neoplastic cells. We report a case of epithelioid PEComa of the falciform ligament and/or broad ligament. There is only one report of such neoplasm in English-language literature. Histologically, the tumor was composed of nests of epithelioid clear cells stained positively for vimentin, HMB45, and SMA. Because of morphological features of the tumour (4 mitoses /20HPF, focal necrosis, and vascular invasion) we assess the neoplasm as potentially malignant.
authors.affiliation: Department of Tumor Pathology, Cracow Center of Oncology, Kraków. z5rys@cyf-kr.edu.pl
authors.forename: Janusz
authors.initials: J
authors.lastname: Ryś
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Karolewski
authors.forename: Jacek
authors.initials: J
authors.lastname: Pudełek
authors.forename: Anna
authors.initials: A
authors.lastname: Kruczak
authors.forename: Anna
authors.initials: A
authors.lastname: Wasilewska
authors.forename: Maria
authors.initials: M
authors.lastname: Vogelgesang
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Kojs
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001956:Broad Ligament / Q000378:metabolism / Q000473:pathology*; D002148:Calmodulin-Binding Proteins / Q000235:genetics; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D054973:Perivascular Epithelioid Cell Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D034802:RNA-Binding Protein EWS; D016601:RNA-Binding Proteins / Q000235:genetics
chemical_list: D014408:Biomarkers, Tumor; D002148:Calmodulin-Binding Proteins; C500986:EWSR1 protein, human; D034802:RNA-Binding Protein EWS; D016601:RNA-Binding Proteins