title: [A case report of FOLFOX treatment for primary duodenal carcinoma with multiple liver metastases].
abstract: We report a case of a woman in her sixties having primary duodenal carcinoma with multiple liver metastases who was treated with oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin(FOLFOX regimen). After completing 2 courses of the chemotherapy, computed tomography showed a partial response without any severe adverse events. Now at 8 months, the PR stage has been maintained. So far, no standard therapeutic strategy for metastatic duodenal carcinoma has been developed. However, we suggest a FOLFOX regimen can be highly effective as a safe approach for continuously maintaining the quality of life of patients with this rare type of cancer.
authors.affiliation: Department of Gastroenterological Surgery, Transplant, and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Naomoto
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tanabe
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Sakurama
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Noma
authors.forename: Toshio
authors.initials: T
authors.lastname: Nishikawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Motoki
authors.forename: Munenori
authors.initials: M
authors.lastname: Takaoka
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shirakawa
authors.forename: Tomoki
authors.initials: T
authors.lastname: Yamatsuji
authors.forename: Junji
authors.initials: J
authors.lastname: Matsuoka
authors.forename: Noriaki
authors.initials: N
authors.lastname: Tanaka
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D004379:Duodenal Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology*; D004384:Duodenoscopy; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000556:secondary*; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil