title: Application of human mini-satellite VNTR probes to genotyping in cynomolgus macaques.
abstract: Cynomolgus macaques (also known as longtail or crab-eating macaques) Macaca fascicularis, are an important non-human primate model for biomedical research. Using a case study involving a suspected occurrence of twin birth, we demonstrate that the highly polymorphic human variable-number tandem repeat (VNTR) mini-satellite probes D1S7, D2S44, D3S42 and D4S184 can be successfully employed as a rapid screening strategy to complement husbandry records in order to establish genetic relatedness in a captive colony.
authors.affiliation: Health Canada, Health Products and Foods Branch, Biologics and Genetic Therapies Directorate, Centre for Biologics Research, Cellular and Molecular Biology Division, AL 2201E Sir FG Banting Research Laboratories, Ottawa, ON, Canada.
authors.forename: Lori
authors.initials: L
authors.lastname: Lavigne-Brunette
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Joly
authors.forename: Susan
authors.initials: S
authors.lastname: Kelly
authors.forename: Chantal J
authors.initials: CJ
authors.lastname: Frégeau
authors.forename: Rémy A
authors.initials: RA
authors.lastname: Aubin
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D002616:Chemical Engineering / Q000379:methods; D004247:DNA / Q000097:blood / Q000235:genetics / Q000302:isolation & purification; D019143:Evolution, Molecular; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000473:pathology; D008252:Macaca fascicularis / Q000235:genetics*; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics*; D050497:Stillbirth
chemical_list: D005819:Genetic Markers; D004247:DNA