Randomized trial of a behavioral weight loss intervention for low-income women: the Weight Wise Program.
Low-income women in the United States have the highest rates of obesity, yet they are seldom included in weight loss trials. To address this research gap, components of two evidence-based weight loss interventions were adapted to create a 16-week intervention for low-income women (Weight Wise Program), which was evaluated in a randomized trial with the primary outcome of weight loss at 5-month follow-up. Participants were low-income women (40-64 years) with a BMI of 25-45. Of 143 participants, 72 were randomized to the Weight Wise Program (WWP) and 71 to the Control Group (CG). Five-month follow-up data were obtained from 64 (89%) WWP and 62 (87%) CG participants. With baseline values carried forward for missing data, WWP participants had a weight change of -3.7 kg compared to 0.7 kg in the CG (4.4 kg difference, 95% confidence interval (CI), 3.2-5.5, P<0.001). For systolic blood pressure (SBP), change in the WWP was -6.5 mm Hg compared to -0.4 mm Hg among controls (6.2 mm Hg difference, 95% CI, 1.7-10.6, P=0.007); for diastolic BP (DBP), changes were -4.1 mm Hg for WWP compared to -1.3 mm Hg for controls (2.8 mm Hg difference, 95% CI, 0.0-5.5, P=0.05). Of the 72 WWP participants, 64, 47, and 19% lost at least 3, 5, and 7% of their initial body weight, respectively. In conclusion, the WWP was associated with statistically significant and clinically important short-term weight loss.
Samuel-Hodge
Carmen D
CD
Department of Nutrition, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA. carmen_samuel@unc.edu
Johnston
Larry F
LF
Gizlice
Ziya
Z
Garcia
Beverly A
BA
Lindsley
Sara C
SC
Bramble
Kathy P
KP
Hardy
Trisha E
TE
Ammerman
Alice S
AS
Poindexter
Patricia A
PA
Will
Julie C
JC
Keyserling
Thomas C
TC
D000328:Adult; D001521:Behavior Therapy / Q000379:methods*; D001794:Blood Pressure / Q000502:physiology; D001823:Body Composition / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011203:Poverty; D012044:Regression Analysis; D012959:Socioeconomic Factors; D015431:Weight Loss / Q000502:physiology*
D002784:Cholesterol