title: Acute acalculous cholecystitis in juvenile systemic lupus erythematosus.
abstract: Small- and medium-vessel vasculitis is a common manifestation in systemic lupus erythematosus (SLE) and may occur in any organ. However, acute acalculous cholecystitis is a rare abdominal manifestation in SLE, especially in children. We report a case of a 12-year-old patient who initially presented with AAC and seizure. Follow-up investigation diagnosed SLE, and brain magnetic resonance imaging had hyperintense white matter lesions in cortico-subcortical regions. The patient was successfully treated with pulse methylprednisolone and cyclophosphamide without surgical intervention.
authors.affiliation: Rheumatology Service, Hospital Vera Cruz, Campinas, Sao Paulo, Brazil.
authors.forename: J A
authors.initials: JA
authors.lastname: Mendonça
authors.forename: J F
authors.initials: JF
authors.lastname: Marques-Neto
authors.forename: P
authors.initials: P
authors.lastname: Prando
authors.forename: S
authors.initials: S
authors.lastname: Appenzeller
mesh_terms: D042101:Acalculous Cholecystitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000208:Acute Disease; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000008:administration & dosage
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone