title: Skin rejuvenation with 1,064-nm Q-switched Nd:YAG laser in Asian patients.
abstract: BACKGROUND
  In recent years, using the 1,064-nm Q-switched neodymium-doped yttrium aluminium garnet (Nd:YAG) laser (QSNYL) with or without exogenous topical carbon solution application for facial skin rejuvenation has become popular in Southeast Asia, but there has not been any published clinical report discussing the rejuvenation effect of QSNYL for Asian patients.
  
  
  OBJECTIVE
  To evaluate the efficacy of QSNYL in improvement of pore size, sebaceous secretion, skin texture, and skin tone of Asian patients. We also observed whether there is any enhancement of application of topical carbon solution before the therapy.
  
  
  METHODS
  Twenty-four female patients completed four sessions of treatments at 4-week intervals. The assessment was evaluated by the patients, two independent physicians, and Canfield VISIA Complexion Analysis. In addition, we conducted a split-face study such that, in each case, topical carbon solution was applied to the right side of the face before the laser treatment.
  
  
  RESULTS
  All evaluations showed significant improvement in rejuvenation effect. There was no difference in improvement in skin texture even after the application of topical carbon solution in our split-face study.
  
  
  CONCLUSIONS
  The QSNYL is a safe and effective rejuvenation modality in Asian patients. Topical carbon solution application did not enhance laser efficacy.
authors.affiliation: Department of Dermatology, Chang Gung Memorial Hospital, Taipei and Taoyuan, Taipei, Taiwan. meichinglee118@yahoo.com.tw
authors.forename: Mei-Ching
authors.initials: MC
authors.lastname: Lee
authors.forename: Sindy
authors.initials: S
authors.lastname: Hu
authors.forename: Min-Chi
authors.initials: MC
authors.lastname: Chen
authors.forename: Yi-Ching
authors.initials: YC
authors.lastname: Shih
authors.forename: Yau-Li
authors.initials: YL
authors.lastname: Huang
authors.forename: Shih-Hung
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000328:Adult; D044466:Asian People; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D011446:Prospective Studies; D012060:Rejuvenation; D015595:Skin Aging / Q000473:pathology / Q000528:radiation effects*; D013624:Taiwan