title: Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide.
abstract: An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.
authors.affiliation: State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Chen
authors.forename: Biao
authors.initials: B
authors.lastname: Yu
mesh_terms: D000925:Anticoagulants / Q000138:chemical synthesis* / Q000737:chemistry; D000990:Antithrombin III / Q000737:chemistry; D006031:Glycosylation; D006493:Heparin / Q000737:chemistry; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000925:Anticoagulants; D009844:Oligosaccharides; C479958:idraparinux; D000990:Antithrombin III; D006493:Heparin