title: Obesity phenotype and intra-abdominal fat responses to regular aerobic exercise.
abstract: OBJECTIVE
  To examine the effects of obesity phenotype on abdominal fat responses to regular aerobic exercise.
  
  
  METHODS
  Fifty-seven obese men aged 34-70 years were divided into two groups based on baseline intra-abdominal fat (IF) area measured by computerized tomography: moderate (<200 cm(2)) IF (MIF; n=33, age: 52.9+/-10.6 [SD] yr, body mass index [BMI]: 29.2+/-3.1 kg/m(2)) or high (>or=200 cm(2)) IF (HIF; n=24, age: 53.5+/-9.5 yr, BMI: 30.3+/-3.1 kg/m(2)). The 12-week exercise program consisted primarily of aerobic exercise and met 3 days per week for 90 min per session. Weight, BMI, body composition (by dual-energy X-ray absorptiometry), IF and subcutaneous fat (SF) areas were measured before and after the program.
  
  
  RESULTS
  Regular aerobic exercise reduced weight by 2.3+/-2.2 kg in MIF and 3.2+/-3.0 kg in HIF. HIF reduced significantly more IF area than MIF (15.1+/-26.0 cm(2) in MIF and 43.3+/-41.9 cm(2) in HIF), and the difference remained significant after adjusting for baseline fat mass, weight change and total energy intake during the 12-week aerobic exercise.
  
  
  CONCLUSIONS
  Exercise-induced IF reduction may be remarkably influenced by obesity phenotype.
authors.affiliation: Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sasai
authors.forename: Yasutomi
authors.initials: Y
authors.lastname: Katayama
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Nakata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ohkubo
authors.forename: Kiyoji
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D050153:Abdominal Fat / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D000328:Adult; D000332:Aerobiosis; D000368:Aged; D050171:Dyslipidemias / Q000188:drug therapy / Q000453:epidemiology; D015444:Exercise; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000235:genetics*; D010101:Oxygen Consumption; D010641:Phenotype; D014057:Tomography, X-Ray Computed; D015431:Weight Loss / Q000502:physiology*
chemical_list: D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents