Identification of an increased short-term blood pressure variability on ambulatory blood pressure monitoring as a coronary risk factor in diabetic hypertensives.
We examined risk factors for coronary heart disease (CHD) by ambulatory blood pressure (BP) monitoring in 72 diabetic hypertensives who were hospitalized for the educational program. The patients were divided into two groups (CHD group, 19 subjects; and non-CHD group, 53 subjects) along with or without co-existing CHD. On ambulatory BP monitoring, no significant differences were found between the groups regarding BP values through the day. However, the CHD group had a significantly greater BP variability than non-CHD group. The result of logistic regression analysis demonstrated that nighttime systolic BP variability was an independent risk factor for CHD.
Ozawa
Motoko
M
Department of Medical Science and Cardiorenal Medicine, Yokohama City University, Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Japan.
Tamura
Kouichi
K
Okano
Yasuko
Y
Matsushita
Kouhei
K
Yanagi
Mai
M
Tsurumi-Ikeya
Yuko
Y
Oshikawa
Jin
J
Hashimoto
Tatsuo
T
Masuda
Shinichiro
S
Wakui
Hiromichi
H
Shigenaga
Atsu-Ichiro
A
Azuma
Kouichi
K
Ishigami
Tomoaki
T
Toya
Yoshiyuki
Y
Ishikawa
Toshiyuki
T
Umemura
Satoshi
S
D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D003327:Coronary Disease / Q000453:epidemiology* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors