Hansen's disease with HIV: a case of immune reconstitution disease.
Immune reconstitution inflammatory syndrome (IRIS) is an acute symptomatic expression of a latent infection during the recovery of the immune system usually as a response to antiretroviral therapy (ART). Opportunistic infections can trigger IRIS. Hansen's disease is an infection caused by Mycobacterium leprae (M. leprae). There have been a limited number of case reports reporting the presentation of the co-infection of HIV and M. leprae. We report an unique case of IRIS in a patient co-infected with HIV and M. leprae presenting as an exacerbation of his Hansen's Disease where the patient's skin lesions progressed from borderline tuberculoid to lepromatous leprosy following ART administration.
Chow
Dominic
D
Department of Medicine, John A Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, USA. dominicc@hawaii.edu
Okinaka
Leila
L
Souza
Scott
S
Shikuma
Cecilia
C
Tice
Alan
A
D000328:Adult; D044966:Anti-Retroviral Agents / Q000276:immunology; D015897:Comorbidity; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000453:epidemiology*; D007918:Leprosy / Q000453:epidemiology* / Q000276:immunology; D008297:Male
D044966:Anti-Retroviral Agents