Delayed adverse reactions to total-dose intravenous iron polymaltose.
The rate of infusion reactions to total-dose intravenous iron polymaltose is very low, but the frequency and severity of adverse reactions following the infusion are unknown. In 50 consecutive patients, adverse reactions developed up to 2 days after the infusion in 26% and lasted 1-8 days (median 4). Severe systemic reactions occurred in 8%. Patients should be warned of the chance of delayed reactions and an alternative iron preparation should be considered if parenteral iron is again indicated.
Haines
M L
ML
Department of Gastroenterology and Hepatology, Monash University, Melbourne, Victoria, Australia.
Gibson
P R
PR
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018771:Arthralgia / Q000139:chemically induced; D002446:Celiac Disease / Q000150:complications; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005334:Fever / Q000139:chemically induced; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006261:Headache / Q000139:chemically induced; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications; D007262:Infusions, Intravenous; D000090463:Iron Deficiencies; D008286:Malabsorption Syndromes / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000150:complications; D055815:Young Adult
D005290:Ferric Compounds; C013276:teferrol