title: Analysis of left ventricular regional dyssynchrony: comparison between real time 3D echocardiography and tissue Doppler imaging.
abstract: BACKGROUND
  There is a paucity of information concerning left ventricular (LV) dyssynchrony assessment by real time three-dimensional (3D) echocardiography (RT3DE) versus tissue Doppler imaging (TDI).
  
  
  OBJECTIVE
  To compare RT3DE and TDI LV dyssynchrony assessment.
  
  
  METHODS
  A prospective study of 92 individuals (56 men, age 47 +/- 10 years), 32 with dilated cardiomyopathy (CMP), and 60 healthy individuals. By RT3DE, we measured the LV% dyssynchrony index (DI) of 6, 12, and 16 segments (SDI). By pulsed-wave TDI, we measured the QS electromechanical interval in the basal segments of the mitral valve annulus of the septum, the lateral, anterior and inferior walls, and the TDI% DI.
  
  
  RESULTS
  In the normal group, the 3D DI was 1.1 +/- 0.8%, 1.4 +/- 1.3%, 1.8 +/- 1.7%, for 6 segments, 12 segments, and SDI, respectively. The correlation coefficient (Pearson's r) for the TDI DI and SDI was r = 0.2381 (P = 0.0470). In CMP group, the 3D DI was 4.6 +/- 5.4%, 7.9 +/- 7.1%, 11.1 +/- 7.1%, for 6 segments, 12 segments, and SDI, respectively. The correlation coefficient for TDI DI and SDI was r = 0.7838 (P < 0.0001).
  
  
  CONCLUSIONS
  We observed a good correlation between RT3DE and tissue Doppler LV dyssynchrony assessment in patients with advanced heart failure.
authors.affiliation: Sector of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil. mluiz766@terra.com.br
authors.forename: Marcelo L C
authors.initials: ML
authors.lastname: Vieira
authors.forename: Alexandre F
authors.initials: AF
authors.lastname: Cury
authors.forename: Gustavo
authors.initials: G
authors.lastname: Naccarato
authors.forename: Wercules A
authors.initials: WA
authors.lastname: Oliveira
authors.forename: Cláudia G
authors.initials: CG
authors.lastname: Mônaco
authors.forename: Ana C T
authors.initials: AC
authors.lastname: Rodrigues
authors.forename: Adriana
authors.initials: A
authors.lastname: Cordovil
authors.forename: Gláucia M P
authors.initials: GM
authors.lastname: Tavares
authors.forename: Edgar B
authors.initials: EB
authors.lastname: Lira Filho
authors.forename: Abraham
authors.initials: A
authors.lastname: Pfeferman
authors.forename: Cláudio H
authors.initials: CH
authors.lastname: Fischer
authors.forename: Samira S
authors.initials: SS
authors.lastname: Morhy
mesh_terms: D003199:Computer Systems; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology*