title: Decomposition of charge-state distributions for better understanding of electrospray mass spectra of bioorganic compounds. Part 2: application of the method.
abstract: The results of the analysis of electrospray mass spectra of b-endorphin and chicken egg lysozyme in different conditions of data acquisition using the method described in Part 1 of the work are reported. At least partial unfolding during the process of ion formation in the electrospray ion source of an initially native biomolecule of lyzozyme in solution should supposedly explain the received set of probabilities of proton retention by basic and acidic residues of this molecule for all considered conditions of data acquisition.
authors.affiliation: Institute for Energy Problems of Chemical Physics RAS, Chernogolovka, Moscow Region, Russia. raznikov@binep.ac.ru
authors.forename: Valeriy V
authors.initials: VV
authors.lastname: Raznikov
authors.forename: Marina O
authors.initials: MO
authors.lastname: Raznikova
mesh_terms: D000818:Animals; D002645:Chickens; D007477:Ions / Q000032:analysis; D009113:Muramidase / Q000737:chemistry*; D010063:Ovum / Q000201:enzymology; D011336:Probability; D011487:Protein Conformation; D017510:Protein Folding; D011522:Protons; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods* / Q000592:standards; D001615:beta-Endorphin / Q000737:chemistry*
chemical_list: D007477:Ions; D011522:Protons; D001615:beta-Endorphin; D009113:Muramidase