title: Kawasaki Disease update.
abstract: Kawasaki Disease is rapidly becoming the most common cause of acquired heart disease in children in both the developed and developing world. Its etiology remains a mystery but important progress has been made in characterizing the features of the arterial wall and myocardial pathology and long-term clinical consequences. New treatments aimed at modifying the host immune response are currently under study. The genetic influence on susceptibility and disease outcome is an area of active research.
authors.affiliation: Department of Pediatrics, UCSD School of Medicine, Rady Children's Hospital, La Jolla, CA 92093, USA. jcburns@ucsd.edu
authors.forename: Jane C
authors.initials: JC
authors.lastname: Burns
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003323:Coronary Aneurysm / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D000069285:Infliximab; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology; D014409:Tumor Necrosis Factor-alpha / Q000627:therapeutic use*; D014657:Vasculitis / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab