title: Vasculitis syndromes: LAMP-2 illuminates pathogenesis of ANCA glomerulonephritis.
abstract: The discovery that antibodies to a bacterial antigen can cross-react with a mammalian protein to cause pauci-immune necrotizing and crescentic glomerulonephritis opens up new possibilities for the diagnosis and treatment of this condition.
authors.affiliation: Department of Internal Medicine, Hospital Clinic, Institut d'Investigació Biomédica August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. xavbosch@clinic.ub.es
authors.forename: Xavier
authors.initials: X
authors.lastname: Bosch
authors.forename: Eduard
authors.initials: E
authors.lastname: Mirapeix
mesh_terms: D000818:Animals; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D005921:Glomerulonephritis / Q000276:immunology*; D006801:Humans; D052119:Lysosomal-Associated Membrane Protein 2; D051907:Lysosomal Membrane Proteins / Q000276:immunology*; D014657:Vasculitis / Q000276:immunology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; C497811:LAMP2 protein, human; D052119:Lysosomal-Associated Membrane Protein 2; D051907:Lysosomal Membrane Proteins