Diabetes insipidus following overdose of baclofen and quetiapine.
We report the case of a patient who presented with coma in the context of baclofen and quetiapine overdose. While the clinical picture was largely in keeping with previous descriptions of baclofen and quetiapine toxicity, the patient went on to exhibit clinical and biochemical features of cranial diabetes insipidus, a finding which has not previously been described in this context.
Silversides
J A
JA
Intensive Care Unit, Antrim Area Hospital, Antrim, Northern Ireland, United Kingdom
Scott
K C
KC
D001418:Baclofen / Q000506:poisoning*; D003919:Diabetes Insipidus / Q000139:chemically induced*; D003987:Dibenzothiazepines / Q000506:poisoning*; D062787:Drug Overdose; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069348:Quetiapine Fumarate
D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D001418:Baclofen