title: Spinal cord compression secondary to brown tumour in a patient on long-term haemodialysis: a case report.
abstract: Brown tumours may occur secondary to hyperparathyroidism in patients with chronic renal failure (CRF). Diagnosing a spinal brown tumour causing cord compression requires a high index of suspicion. We report a 65-year-old woman, who had been on haemodialysis for CRF for over 10 years, who presented with leg weakness and back pain over the thoracolumbar junction. She had a brown tumour at T8 causing subacute spinal cord compression. Ambulation was regained after surgical decompression and stabilisation. Adherence to the National Kidney Foundation guidelines in the management of patients with CRF may prevent renal osteodystrophy. Treatment of spinal brown tumour depends on the severity of the neurological deficit. Remineralization is expected after correction of the parathyroid level, thus negating the need for total excision of the parathyroid glands.
authors.affiliation: Department of Orthopaedics and Traumatology, Queen Mary Hospital, University of Hong Kong, Hong Kong. kincmak@gmail.com
authors.forename: K C
authors.initials: KC
authors.lastname: Mak
authors.forename: Y W
authors.initials: YW
authors.lastname: Wong
authors.forename: K D K
authors.initials: KD
authors.lastname: Luk
mesh_terms: D000368:Aged; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D006435:Renal Dialysis; D013117:Spinal Cord Compression / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013125:Spinal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013904:Thoracic Vertebrae