title: Persisting muscle atrophy two years after replacement of the hip.
abstract: Muscle atrophy has been demonstrated in patients suffering from osteoarthritis of the hip, but little is known about muscular recovery after total hip replacement (THR). A total of 20 patients with unilateral osteoarthritis of the hip were assessed before, six months and two years after THR. The cross-sectional area and radiological density of the muscles of the hip, thigh, calf and back were measured using CT. We hypothesised that the muscles would not recover fully after operation. After two years comparison of the limb with the THR with the healthy limb showed that there was such a reduction in the cross-sectional area in iliopsoas (7.0%; p = 0.006) and the hip adductors (8.4%, p = 0.003) and in the radiological density in gluteus maximus (10.1 Hounsfield units; p < 0.001), gluteus medius/minimus (5.6 Hounsfield units; p = 0.011), iliopsoas (3.9 Hounsfield units; p < 0.001) and the adductors (2.4 Hounsfield units; p = 0.022). Thus, there was persistent muscle atrophy in muscles acting about the hip two years after THR. We suggest that an earlier operation or a more intensive rehabilitation may reverse these changes.
authors.affiliation: Department of Clinical Sciences, Division of Orthopaedic Surgery, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden. anton.rasch@ds.se
authors.forename: A
authors.initials: A
authors.lastname: Rasch
authors.forename: A H
authors.initials: AH
authors.lastname: Byström
authors.forename: N
authors.initials: N
authors.lastname: Dalén
authors.forename: N
authors.initials: N
authors.lastname: Martinez-Carranza
authors.forename: H E
authors.initials: HE
authors.lastname: Berg
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D002081:Buttocks / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging* / Q000473:pathology; D009133:Muscular Atrophy / Q000000981:diagnostic imaging* / Q000473:pathology; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed