[Is statin treatment for children safe and effective?].
The recommendation of statin treatment to younger patients too, as recently issued by the American Academy of Pediatrics, appeared to be controversial, especially looking at the lack of evidence in term of efficacy on primary end-point and long term safety data.
Marchetti
Federico
F
Clinica Pediatrica, IRCCS Burlo Garofalo, Università, Trieste. marchetti@burlo.trieste.it
Cannioto
Zemira
Z
D000293:Adolescent; D017668:Age of Onset; D000924:Anticholesteremic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D035843:Biomedical Research; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D002648:Child; D008078:Cholesterol, LDL / Q000097:blood; D015510:Clinical Medicine; D019317:Evidence-Based Medicine; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D006938:Hyperlipoproteinemia Type II / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D009765:Obesity / Q000209:etiology / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D018570:Risk Assessment
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors