Phenolic compounds with cell protective activity from the fruits of Livistona chinensis.
Two new depsidones, livistones A (1) and B (2), and a new benzofurane, livistone C (3), together with the 11 known compounds including three stilbenes (4-6), four steroids, three flavan-3-ols, and an alkaloid were isolated from the fruits of Livistona chinensis. The structures of the new compounds were determined by spectroscopic methods. Compounds 1, 4-6 exhibited remarkable cell protective activities against H(2)O(2)-induced SH-SY5Y cell damage.
Yuan
Tao
T
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Yang
Sheng-Ping
SP
Zhang
Hai-Yan
HY
Liao
Shang-Gao
SG
Wang
Wei
W
Wu
Yan
Y
Tang
Xi-Can
XC
Yue
Jian-Min
JM
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D028023:Arecaceae / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D053630:Depsides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010082:Oxepins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification
D000470:Alkaloids; D001572:Benzofurans; D053630:Depsides; D004365:Drugs, Chinese Herbal; D007783:Lactones; D010082:Oxepins; D010636:Phenols; D010840:Phytosterols; D013267:Stilbenes; C540732:livistone A; C540733:livistone B; C540734:livistone C; C000875:depsidone; D006861:Hydrogen Peroxide