title: The tangled web of signaling in innate immunity.
abstract: Similarities in innate immune signaling exist between mammals and the nematode Caenorhabditis elegans. Now, Ziegler et al. (2009) and Ren et al. (2009) demonstrate that a protein kinase C delta homolog in C. elegans is involved in innate immunity, providing evidence that the conservation of immune signaling networks extends further than previously thought.
authors.affiliation: Division of Infection Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Coleman
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Mylonakis
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000201:enzymology* / Q000276:immunology*; D007113:Immunity, Innate; D008954:Models, Biological; D051745:Protein Kinase C-delta / Q000378:metabolism*
chemical_list: D051745:Protein Kinase C-delta