Long-term follow-up results of fertility sparing surgery in patients with epithelial ovarian cancer.
OBJECTIVE
To assess clinical and obstetric outcome in young patients with epithelial ovarian cancer treated with fertility sparing surgery.


METHODS
Eighteen patients younger than 40 years carrying epithelial ovarian tumors were submitted to fertility sparing surgery between 1988 and 2003. Disease-free (DFS) and overall survival (OS) were analyzed using the Kaplan-Meier method. Statistical analysis was performed with the chi(2) test.


RESULTS
Disease free survival (DFS) 83.3% and overall survival (OS) 94.4% of patients treated with conservative surgery at 10 years. Up to date, six of seven patients who attempted pregnancy delivered seven healthy newborns.


CONCLUSIONS
Conservative surgery in young women with epithelial ovarian cancer is an appropriate therapeutic option in patients who wish to preserve childbearing potential. Long-term follow-up results shows excellent overall survival and pregnancy results.
Anchezar
Juan P
JP
Gynecologic Oncology Program, Buenos Aires University, Buenos Aires, Argentina. janch@intramed.net
Sardi
Juan
J
Soderini
Alejandro
A
D000328:Adult; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000401:mortality / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000401:mortality / Q000601:surgery*; D011379:Prognosis