title: Discovery and optimization of a TRAIL R2 agonist for cancer therapy.
authors.affiliation: Affymax, Inc., 4001 Miranda Avenue, Palo Alto, CA 94304, USA.
authors.forename: Yvonne M
authors.initials: YM
authors.lastname: Angell
authors.forename: Ashok
authors.initials: A
authors.lastname: Bhandari
authors.forename: M Nuria
authors.initials: MN
authors.lastname: De Francisco
authors.forename: Brian T
authors.initials: BT
authors.lastname: Frederick
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Green
authors.forename: Karen
authors.initials: K
authors.lastname: Leu
authors.forename: Kerstin
authors.initials: K
authors.lastname: Leuther
authors.forename: Reuben
authors.initials: R
authors.lastname: Sana
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Schatz
authors.forename: Erik A
authors.initials: EA
authors.lastname: Whitehorn
authors.forename: Kathy
authors.initials: K
authors.lastname: Wright
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Holmes
mesh_terms: D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D055808:Drug Discovery; D006801:Humans; D013058:Mass Spectrometry; D018716:Molecular Mimicry; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000188:drug therapy*; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand / Q000819:agonists*
chemical_list: D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand