title: Orally administered lemon/orange juice improved MRCP imaging of pancreatic ducts.
abstract: BACKGROUND
  The aim of this study was to determine the effectiveness of oral administration of lemon/orange juice in improving the visualization of pancreatic ducts on MRCP.
  
  
  METHODS
  MRCP images were generated before and at every 15 min for 90 min after oral administration of lemon/orange juice in a dose of 2 ml/kg in 20 volunteers and 26 patients. The pre- and post-administration images were compared and analyzed qualitatively and quantitatively.
  
  
  RESULTS
  In 20 volunteers and 26 patients, the visualization at pancreatic duct of head, body, tail, accessory pancreatic duct, and branch duct was improved after juice administration. The diameter of pancreatic ducts was augmented, and the differences in the mean values before and after oral juice were highly significant at both sites in volunteers and patients (P < 0.01). In 20 volunteers and 26 patients, after juice administration, the best visualization of the pancreatic duct was achieved at (58.98 +/- 14.96) min and (59.41 +/- 13.79) min, respectively, and the overlap imaging of oral juice was especially observed at (42.86 +/- 10.92) min and (41.63 +/- 9.32) min, respectively.
  
  
  CONCLUSIONS
  Orally lemon/orange juice is an effective method to improve MRCP imaging of pancreatic ducts. The lemon/orange juice should be administered at 60 min prior to MRCP.
authors.affiliation: Department of General Surgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Chu
authors.forename: Qian
authors.initials: Q
authors.lastname: Ji
authors.forename: Jia-Lin
authors.initials: JL
authors.lastname: Zhang
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001628:Beverages; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D003287:Contrast Media; D005260:Female; D005638:Fruit; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts; D011446:Prospective Studies
chemical_list: D003287:Contrast Media