title: [Immunologic theory investigation and discussion of pain caused by lumbar intervertebral disc herniation (LDH)].
abstract: To explore the main clinical manifestation (lower back pain and ischialgia) of LDH with immunologic method and study the relationship and clinical significance of the cardinal symptom (pain) and immune comple (IC), macrophage (MP),interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor (TNF), prostaglandin E2 (PGE2), phosphatidase A2 (PLA2), nitrogen monoxidum (NO) expressing, finding a new way in order to prevention and cure of LDH. We will review immunologic theory of LDH pain.
authors.affiliation: The Traditional Chinese Medical Hospital of Gansu Province, Lanzhou 730000, Gansu, China.
authors.forename: Sheng-hua
authors.initials: SH
authors.lastname: Li
authors.forename: Jiu-xia
authors.initials: JX
authors.lastname: Wang
authors.forename: Jia-hong
authors.initials: JH
authors.lastname: Zhang
mesh_terms: D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications* / Q000276:immunology* / Q000378:metabolism; D008159:Lumbar Vertebrae / Q000473:pathology*; D009569:Nitric Oxide / Q000378:metabolism; D010146:Pain / Q000209:etiology* / Q000276:immunology* / Q000378:metabolism; D054467:Phospholipases A2 / Q000378:metabolism
chemical_list: D016207:Cytokines; D009569:Nitric Oxide; D054467:Phospholipases A2