title: Langerhans cell histiocytosis of the sternum.
abstract: We report a rare case of Langerhans cell histiocytosis involving the sternum. The patient was a 12-year-old girl presenting with anterior chest pain and swelling. Radiographs and computed tomography showed an osteolytic lesion in the sternum. Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia. Incisional biopsy for the sternum lesion was performed, and the histopathologic diagnosis was Langerhans cell histiocytosis. She was treated with chemotherapy and the symptoms disappeared.
authors.affiliation: Department of Orthopedic Surgery, Akita University School of Medicine, 1-1-1 Hondo, Akita, Japan. tsuchie@doc.med.akita-u.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tsuchie
authors.forename: Kyoji
authors.initials: K
authors.lastname: Okada
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nagasawa
authors.forename: Michihiro
authors.initials: M
authors.lastname: Yano
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nanjyo
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Shimada
mesh_terms: D002637:Chest Pain; D002648:Child; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D013249:Sternum / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed