title: Non-invasive optical mapping of the piglet brain in real time.
abstract: We have performed non-invasive, real-time optical mapping of the piglet brain during a subcortical injection of autologous blood. The time resolution of the optical maps is 192 ms, thus allowing us to generate a real-time video of the growing subcortical hematoma. The increased absorption at the site of blood injection is accompanied by a decreased absorption at the contralateral brain side. This contralateral decrease in the optical absorption and the corresponding time traces of the cerebral hemoglobin parameters are consistent with a reduced cerebral blood flow caused by the increased intracranial pressure.
authors.forename: S
authors.initials: S
authors.lastname: Fantini
authors.forename: M
authors.initials: M
authors.lastname: Franceschini
authors.forename: E
authors.initials: E
authors.lastname: Gratton
authors.forename: D
authors.initials: D
authors.lastname: Hueber
authors.forename: W
authors.initials: W
authors.lastname: Rosenfeld
authors.forename: D
authors.initials: D
authors.lastname: Maulik
authors.forename: P
authors.initials: P
authors.lastname: Stubblefield
authors.forename: M
authors.initials: M
authors.lastname: Stankovic