Peripheral arterial disease and clinical risks in Taiwanese hemodialysis patients.
Peripheral arterial disease (PAD) is associated with significant morbidity and mortality and is an important marker of systemic atherosclerosis. However, little is known about the associated risk factors for PAD in patients on maintenance hemodialysis (HD). We collected the basic data and possible risk factors associated with PAD for 277 patients on maintenance HD. Furthermore, we measured ankle-brachial blood pressure index (ABI) in these patients. PAD was defined as an ABI value less than 0.90. The prevalence of PAD in our HD center was 22.8% (61/268). Advanced age (P = 0.006), longer history of HD (P < 0.001), diabetes (P = 0.002) and presence of PAD symptoms (P < 0.001) were independent predictors of PAD. PAD patients with diabetes had shorter history of HD (P = 0.001). 2-vessel PAD had higher serum cholesterol in HD patients (>or= 200 vs < 200 mg/dL; Odds ratio, 12.12, 95% confidence interval, 2.199-67.79; P < 0.004).
Liu
Jiung-Hsiun
JH
Division of Nephrology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan. jiunghsiun@yahoo.com.tw
Chang
Chin-Cheng
CC
Wang
Shu-Ming
SM
Chou
Che-Yi
CY
Yang
Ya-Fei
YF
Liu
Yao-Lung
YL
Lin
Hsin-Hung
HH
Huang
Chiu-Ching
CC
D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000453:epidemiology* / Q000209:etiology; D006435:Renal Dialysis; D012307:Risk Factors; D013624:Taiwan