Maize arabinoxylan gels as protein delivery matrices.
The laccase induced gelation of maize bran arabinoxylans at 2.5% (w/v) in the presence of insulin or beta-lactoglobulin at 0.1% (w/v) was investigated. Insulin and beta-lacto-globulin did not modify either the gel elasticity (9 Pa) or the cross-links content (0.03 and 0.015 microg di- and triferulic acids/mg arabinoxylan, respectively). The protein release capability of the gel was also investigated. The rate of protein release from gels was dependent on the protein molecular weight. The apparent diffusion coefficient was 0.99 x 10(-7) and 0.79 x 10(-7) cm(2)/s for insulin (5 kDa) and beta-lactoglobulin (18 kDa), respectively. The results suggest that maize bran arabinoxylan gels can be potential candidates for the controlled release of proteins.
Berlanga-Reyes
Claudia M
CM
Laboratorio de Biopolímeros, Centro de Investigación en Alimentación y Desarrollo, Unidad Cuauhtémoc, Ciudad Cuauhtémoc, Chihuahua, México.
Carvajal-Millán
Elizabeth
E
Lizardi-Mendoza
Jaime
J
Rascón-Chu
Agustin
A
Marquez-Escalante
Jorge A
JA
Martínez-López
Ana Luisa
AL
D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D016503:Drug Delivery Systems; D005782:Gels / Q000737:chemistry* / Q000378:metabolism; D007328:Insulin / Q000378:metabolism; D042845:Laccase / Q000378:metabolism; D007782:Lactoglobulins / Q000378:metabolism; D008970:Molecular Weight; D010940:Plant Proteins / Q000378:metabolism; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D014990:Xylans / Q000737:chemistry* / Q000378:metabolism; D003313:Zea mays / Q000737:chemistry*
D001672:Biocompatible Materials; D005782:Gels; D007328:Insulin; D007782:Lactoglobulins; D010940:Plant Proteins; D011506:Proteins; D014990:Xylans; C085118:arabinoxylan; D042845:Laccase