title: Serum eye drops, amniotic membrane and limbal epithelial stem cells--tools in the treatment of ocular surface disease.
abstract: The advent of serum eye drops, amniotic membrane and limbal stem cell grafts, have transformed the treatment of diseases which result in ocular surface failure. This article provides an overview of ocular surface anatomy and failure, and how the use of serum eye drops, amniotic membrane and limbal epithelial stem cell transplantation has influenced ophthalmological practice both historically and in recent years. This review focuses on the rationale for the use of these emerging tools, how they are prepared, clinical applications, limitations, and speculates on future directions.
authors.affiliation: Academic Unit of Ophthalmology, School of Immunity and Infection, College of Medical and Dental Sciences, Birmingham and Midland Eye Centre, University of Birmingham, Dudley Road, Birmingham, B18 7QU, UK. s.rauz@bham.ac.uk
authors.forename: Saaeha
authors.initials: S
authors.lastname: Rauz
authors.forename: Valerie P
authors.initials: VP
authors.lastname: Saw
mesh_terms: D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D003316:Corneal Diseases / Q000175:diagnosis / Q000628:therapy*; D019573:Epithelium, Corneal / Q000637:transplantation*; D005131:Eye Injuries / Q000628:therapy*; D006801:Humans; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D044967:Serum
chemical_list: D009883:Ophthalmic Solutions