Improvements to selective refocusing phased (SERFph) experiments.
Selective refocusing experiments are very powerful for extracting proton-proton couplings one by one. However we demonstrate in the present work that various spectral artefacts are produced by the initial sequence and we show that the combined addition of a refocusing pi pulse and a zero-quantum filter greatly improves the experimental sensitivity, and moreover leads to observation of pure absorption lineshapes in the resulting phased 2D spectrum. These developments are applied to the differentiation of enantiomers dissolved in a chiral liquid crystal.
Beguin
L
L
Laboratoire de RMN en milieu orienté, Université Paris-Sud 11, ICMMO, UMR CNRS 8182, Bat. 410, 91405 Orsay cedex, France.
Giraud
N
N
Ouvrard
J M
JM
Courtieu
J
J
Merlet
D
D
D000465:Algorithms; D050866:Liquid Crystals / Q000032:analysis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011522:Protons; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D011522:Protons