title: Nanomolar Hg(II) detection using Nile blue chemodosimeter in biological media.
abstract: A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg(2+) ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg(2+) ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea.
authors.forename: Min Hee
authors.initials: MH
authors.lastname: Lee
authors.forename: Soon W
authors.initials: SW
authors.lastname: Lee
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Chulhun
authors.initials: C
authors.lastname: Kang
authors.forename: Jong Seung
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000418:Albumins / Q000737:chemistry; D003124:Colorimetry; D005456:Fluorescent Dyes / Q000737:chemistry*; D005470:Fluorometry; D008628:Mercury / Q000032:analysis* / Q000097:blood; D015394:Molecular Structure; D036103:Nanotechnology; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry*; D010670:Phenylthiourea / Q000138:chemical synthesis* / Q000737:chemistry; D012995:Solubility; D014867:Water / Q000737:chemistry
chemical_list: D000418:Albumins; D005456:Fluorescent Dyes; C541186:Nile blue-based chemodosimeter; D010078:Oxazines; D014867:Water; C008619:Nile Blue; D010670:Phenylthiourea; D008628:Mercury