Neurocytoma of the spinal cord: report of three cases and review of the literature.
The spinal cord is a very rare location for extra-ventricular neurocytomas. Composed of small round cells with neuronal differentiation, neurocytoma has a particularly favourable prognosis. Long disease-free intervals have been observed in patients who received sub-total removal and radiotherapy. A careful intra-operative frozen section examination is helpful in avoiding excessive surgical tissue disturbance and to identify the best treatment option. To date, eight cases of neurocytoma of the spinal cord have been described. We report three more patients; one with very long survival, and review the published literature for this condition.
Polli
Filippo Maria
FM
Neurosurgery, Department of Neurosciences, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161 Roma, Italy. filippom-polli@usa.net
Salvati
Maurizio
M
Miscusi
Massimo
M
Delfini
Roberto
R
Giangaspero
Felice
F
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D018306:Neurocytoma / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D019635:Neurosurgical Procedures; D011183:Postoperative Complications / Q000209:etiology; D011878:Radiotherapy; D017678:Sex Distribution; D013116:Spinal Cord / Q000473:pathology* / Q000503:physiopathology; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D013595:Syringomyelia / Q000209:etiology / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome