title: [The cnr-like operon in strain Comamonas sp. encoding resistance to cobalt and nickel].
abstract: Plasmid pBS501 was detected in the strain Comamonas sp. BS501. This plasmid specifies high level of induced resistance (5 mM) to cobalt/nickel both in the host strain and in related strains C. testosteroni B-1241 and C. acidovorans B-1251. Hybridization analysis revealed a homology of pBS501 restriction fragments with the only well-characterized operon cnrXYHCBAT that resides in plasmid pMOL28 from Cupriavidus metallidurans CH34. Essential differences in the structural organization of the cobalt/nickel resistance determinant were found between plasmid pBS501 and the cnr-operon.
authors.forename: T V
authors.initials: TV
authors.lastname: Siunova
authors.forename: A V
authors.initials: AV
authors.lastname: Siunov
authors.forename: V V
authors.initials: VV
authors.lastname: Kochetkov
authors.forename: A M
authors.initials: AM
authors.lastname: Boronin
mesh_terms: D003035:Cobalt / Q000494:pharmacology*; D020585:Comamonas / Q000235:genetics* / Q000378:metabolism; D024881:Drug Resistance, Bacterial / Q000187:drug effects / Q000502:physiology*; D009532:Nickel / Q000494:pharmacology*; D009876:Operon / Q000502:physiology*; D010957:Plasmids / Q000235:genetics* / Q000378:metabolism
chemical_list: D003035:Cobalt; D009532:Nickel