Patient sex and its influence on general anaesthesia.
Physiological and pharmacological differences exist between men and women. Women wake faster than men following general anaesthesia. Women also differ from men in their postoperative recovery as reflected by differences in postoperative pain, nausea and vomiting and overall quality of recovery. These gender differences seem to be more pronounced in premenopausal women, suggesting hormonal mechanisms are a major contributing factor.
Buchanan
F F
FF
Department of Anaesthesia and Perioperative Medicine, Alfred Hospital and Academic Board of Anaesthesia and Perioperative Medicine, Monash University, Melbourne, Victoria, Australia.
Myles
P S
PS
Cicuttini
F
F
D000768:Anesthesia, General; D000777:Anesthetics / Q000493:pharmacokinetics / Q000494:pharmacology; D001823:Body Composition; D001831:Body Temperature; D001921:Brain / Q000502:physiology; D051544:Cytochrome P-450 CYP3A / Q000378:metabolism; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D008297:Male; D011485:Protein Binding; D012119:Respiration; D012727:Sex Characteristics
D000777:Anesthetics; D005640:Follicle Stimulating Hormone; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human