Fibroblast "cilia growth" factor in the development of left-right asymmetry.
Although fibroblast growth factor (FGF) signaling is critical for many developmental processes, the cellular mechanism(s) by which FGF exerts its effects remains obscure. In recent papers, Neugebauer et al. and Hong and Dawid focus on the role of FGF signaling on left-right axis patterning, showing that FGF functions at least in part via an effect on ciliogenesis.
Basu
Basudha
B
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA.
Brueckner
Martina
M
D000818:Animals; D019521:Body Patterning; D002923:Cilia / Q000378:metabolism*; D005346:Fibroblast Growth Factors / Q000378:metabolism; D005347:Fibroblasts / Q000378:metabolism*; D015398:Signal Transduction
D005346:Fibroblast Growth Factors