title: Design and synthesis of cyclic arodyn analogues by ring-closing metathesis (RCM) for kappa opioid receptor (KOP) antagonists.
authors.affiliation: Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 66045, USA.
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Fang
authors.forename: Santosh S
authors.initials: SS
authors.lastname: Kulkarni
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Murray
authors.forename: Jane V
authors.initials: JV
authors.lastname: Aldrich
mesh_terms: D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D015195:Drug Design; D004399:Dynorphins / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D017473:Receptors, Opioid, kappa / Q000037:antagonists & inhibitors*
chemical_list: D017473:Receptors, Opioid, kappa; C470200:arodyn; D004399:Dynorphins