A computational dosimetry tool for the study of tumor doses and skin toxicities in BNCT.
A Matlab-based computational tool, named SPHERE, was developed that helps determining tumor and skin doses in BNCT treatments. It was especially designed for cutaneous melanoma treatments and, among its features, it provides a guide for the location and delineation of tumors and a visual representation of superficial dose distributions (for both tumor and normal tissues). It also generates cumulative dose-volume histograms for different volumes of interest and dose-area histograms for skin. A description of the tool is presented, as well as examples of its application.
Gossio
Sebastián
S
FCEyN, Pab. II Ciudad Universitaria, UBA, (1428) Cdad. de Buenos Aires, Argentina.
Carando
Daniel G
DG
González
Sara J
SJ
D001118:Argentina; D016754:Boron Neutron Capture Therapy / Q000009:adverse effects* / Q000706:statistics & numerical data*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000517:prevention & control*; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data*; D012867:Skin / Q000293:injuries / Q000528:radiation effects; D012878:Skin Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D012984:Software