Factor IX and deep vein thrombosis.
Elevated levels of several coagulation factors have been found to be associated with an increased risk of thrombosis. In this perspective article, Dr. Lowe examines the implications of the report by Bezemer and coworkers in this issue for our understanding of the mechanisms involved and how they should direct future research.
Lowe
Gordon
G
D005164:Factor IX / Q000235:genetics* / Q000378:metabolism; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D016017:Odds Ratio; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D020246:Venous Thrombosis / Q000097:blood / Q000235:genetics*
D005164:Factor IX