title: Identification of an increased short-term blood pressure variability on ambulatory blood pressure monitoring as a coronary risk factor in diabetic hypertensives.
abstract: We examined risk factors for coronary heart disease (CHD) by ambulatory blood pressure (BP) monitoring in 72 diabetic hypertensives who were hospitalized for the educational program. The patients were divided into two groups (CHD group, 19 subjects; and non-CHD group, 53 subjects) along with or without co-existing CHD. On ambulatory BP monitoring, no significant differences were found between the groups regarding BP values through the day. However, the CHD group had a significantly greater BP variability than non-CHD group. The result of logistic regression analysis demonstrated that nighttime systolic BP variability was an independent risk factor for CHD.
authors.affiliation: Department of Medical Science and Cardiorenal Medicine, Yokohama City University, Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Japan.
authors.forename: Motoko
authors.initials: M
authors.lastname: Ozawa
authors.forename: Kouichi
authors.initials: K
authors.lastname: Tamura
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Okano
authors.forename: Kouhei
authors.initials: K
authors.lastname: Matsushita
authors.forename: Mai
authors.initials: M
authors.lastname: Yanagi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Tsurumi-Ikeya
authors.forename: Jin
authors.initials: J
authors.lastname: Oshikawa
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Masuda
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Wakui
authors.forename: Atsu-Ichiro
authors.initials: A
authors.lastname: Shigenaga
authors.forename: Kouichi
authors.initials: K
authors.lastname: Azuma
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Ishigami
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Toya
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemura
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D003327:Coronary Disease / Q000453:epidemiology* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors