title: Sensitivity and specificity of Chagas Stat-Pak test in Bolivia.
abstract: OBJECTIVE
  To compare the results of an immunochromatographic test performed on whole blood, Chagas Stat-Pak, with those of an ELISA test using recombinant antigens.
  
  
  METHODS
  We tested 995 subjects of a rural population of all ages in the south of Bolivia, 459 pregnant women of the same population and 1030 urban women giving birth from the east of Bolivia.
  
  
  RESULTS
  The sensitivity of the CSP test for the entire studied population (n = 2484) was 94.73% [93.35-96.10]; the specificity was 97.33% [96.50-98.15]. However, the specificity differed significantly between rural pregnant and urban birthing women, which could be attributed either to differences of parasite strain or Chagas prevalence.
  
  
  CONCLUSIONS
  The test is simple of use, reliable, relatively inexpensive (<2 US$ each test) and its performances are compatible with a field use for large-scale screenings.
authors.affiliation: Institut de Recherche pour le Développement, La Paz, Bolivia. jean-philippe.chippaux@ird.fr
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Chippaux
authors.forename: Jose A
authors.initials: JA
authors.lastname: Santalla
authors.forename: Jorge R
authors.initials: JR
authors.lastname: Postigo
authors.forename: Mario
authors.initials: M
authors.lastname: Romero
authors.forename: Nadin A
authors.initials: NA
authors.lastname: Salas Clavijo
authors.forename: Dominique
authors.initials: D
authors.lastname: Schneider
authors.forename: Laurent
authors.initials: L
authors.lastname: Brutus
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology; D001838:Bolivia / Q000453:epidemiology; D014355:Chagas Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011446:Prospective Studies; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012680:Sensitivity and Specificity; D014349:Trypanosoma cruzi / Q000276:immunology / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D000953:Antigens, Protozoan; D011933:Reagent Kits, Diagnostic