Management of central diabetes insipidus with oral desmopressin in a patient with ectrodactyly and cleft lip/palate (ECP) syndrome.
We present a female infant with facial abnormalities such as bilateral cleft lip and palate, ectrodactyly and central diabetes insipidus. She had a history of recurrent hypernatremic attacks and she was treated successfully with oral desmopressin. As an alternative to the nasal route, long-term management was achieved using oral route and she had a favorable growth and development during infancy.
Ozaydin
Eda
E
Ankara Dişkapi Children's Hospital, Ankara, Turkey.
Aycan
Zehra
Z
Yusufoğlu
Arzu Meltem
AM
Cetinkaya
Ergun
E
Ergen
Saime
S
Unal
Sevim
S
Köse
Gülşen
G
D000015:Abnormalities, Multiple; D050034:Antidiuretic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002971:Cleft Lip / Q000453:epidemiology*; D002972:Cleft Palate / Q000453:epidemiology*; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage / Q000627:therapeutic use*; D020790:Diabetes Insipidus, Neurogenic / Q000188:drug therapy* / Q000453:epidemiology / Q000378:metabolism; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D014034:Toes / Q000002:abnormalities*
D050034:Antidiuretic Agents; D003894:Deamino Arginine Vasopressin