title: Gelatin sponge insertion into tympanostomy tubes: an in-vitro study to evaluate postoperative obstruction.
abstract: OBJECTIVE
  To analyze the efficacy of gelatin sponge insertion into lumens of tympanostomy tubes to prevent obstruction in the presence of blood.
  
  
  METHODS
  In vitro model.
  
  
  METHODS
  Absorbable gelatin sponge wicks were placed in the lumen of Ultrasil Collar Button ventilation tubes and Shepherd Grommet ventilation tubes. One half of each group was covered with blood, the other left untreated. Each tube was treated with ofloxacin solution three times daily for seven days. After treatment, the tubes were inspected. Reinspection was performed after brief suctioning. Numerical scores were given based on degree of obstruction.
  
  
  RESULTS
  A statistically significant difference in degree of obstruction (P < 0.0001) was seen between all tubes with wicks alone versus those with blood added. After re-evaluation, there remained a statistically significant difference between tubes with wicks alone and tubes with wicks and blood (P < 0.0001).
  
  
  CONCLUSIONS
  Gelatin sponge insertion does not prevent, and may in fact, enhance, obstruction of pressure equalization tube lumens in the presence of blood.
authors.affiliation: Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Kentucky College of Medicine, Lexington KY, USA.
authors.forename: Chad P
authors.initials: CP
authors.lastname: Secor
authors.forename: Robert E
authors.initials: RE
authors.lastname: Wilson
authors.forename: Paul M
authors.initials: PM
authors.lastname: Spring
authors.forename: Richard C
authors.initials: RC
authors.lastname: Haydon
mesh_terms: D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001769:Blood; D005781:Gelatin Sponge, Absorbable; D006801:Humans; D066298:In Vitro Techniques; D008876:Middle Ear Ventilation / Q000295:instrumentation*; D015242:Ofloxacin / Q000008:administration & dosage; D011183:Postoperative Complications / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D015242:Ofloxacin