title: Generalized tularemia in a vervet monkey (Chlorocebus aethiops) and a patas monkey (Erythrocebus patas) in a zoo.
abstract: Generalized tularemia was diagnosed in a vervet monkey (Chlorocebus aethiops) and a patas monkey (Erythrocebus patas), both of which died suddenly in the Szeged Zoo, Szeged, Hungary. Macroscopic lesions in each animal included disseminated, grayish-white foci in the lungs, lymph nodes, spleen, liver, and kidney. All focal lesions were characterized microscopically as purulent to pyogranulomatous to granulomatous inflammation with necrosis. Francisella tularensis subsp. holarctica strains were isolated from tissue samples on modified Francis agar after mouse passage and identified by a commercial carbon-source utilization test and polymerase chain reaction-based amplification and sequencing of a portion of the 16S ribosomal RNA gene.
authors.affiliation: Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent István University, Hungária krt. 23-25, H-1143 Budapest, Hungary. Gyuranecz.Miklos@aotk.szie.hu
authors.forename: Miklós
authors.initials: M
authors.lastname: Gyuranecz
authors.forename: László
authors.initials: L
authors.lastname: Fodor
authors.forename: László
authors.initials: L
authors.lastname: Makrai
authors.forename: István
authors.initials: I
authors.lastname: Szoke
authors.forename: Katalin
authors.initials: K
authors.lastname: Jánosi
authors.forename: Katalin
authors.initials: K
authors.lastname: Krisztalovics
authors.forename: Károly
authors.initials: K
authors.lastname: Erdélyi
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D002522:Chlorocebus aethiops; D004901:Erythrocebus patas; D017809:Fatal Outcome; D005260:Female; D008168:Lung / Q000473:pathology; D008297:Male; D013154:Spleen / Q000473:pathology; D014406:Tularemia / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*