Encapsulation and sustained release of curcumin using superparamagnetic silica reservoirs.
For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe(3)O(4) particles surrounded by a silica matrix.
Chin
Suk Fun
SF
Centre for Strategic Nano-Fabrication, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Iyer
K Swaminathan
KS
Saunders
Martin
M
St Pierre
Tim G
TG
Buckley
Craig
C
Paskevicius
Mark
M
Raston
Colin L
CL
D003474:Curcumin / Q000008:administration & dosage*; D016503:Drug Delivery Systems; D005290:Ferric Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D053758:Nanoparticles / Q000627:therapeutic use; D012822:Silicon Dioxide / Q000737:chemistry*; D014867:Water
D005290:Ferric Compounds; D014867:Water; C000499:ferric oxide; D012822:Silicon Dioxide; D003474:Curcumin