[Antibiotic management of pediatric presumptive bacterial meningitis (rational, methods, course, and follow-up)].
The epidemiology of acute community-acquired bacterial meningitis in children in industrialized nations was greatly modified because of recommended vaccination against Haemophilus influenzae b, Streptococcus pneumoniae (SP) and in some countries against Neisseria meningitidis (Nm) group C. However, most cases of bacterial meningitis are caused by SP and Nm most frequently group B, which validates the first intention use of cefotaxime or ceftriaxone combined or not with vancomycin according to the probability of pneumococcal resistance.
Haas
Hervé
H
Service d'urgences pédiatriques, hôpital Archet 2, CHU de Nice, 151, route de Saint-Antoine-de-Ginestière, 06202 Nice cedex 03, France. haas.h@chu-nice.fr
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000453:epidemiology; D019049:Developed Countries / Q000706:statistics & numerical data; D004359:Drug Therapy, Combination; D005602:France / Q000453:epidemiology; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D016920:Meningitis, Bacterial / Q000188:drug therapy* / Q000453:epidemiology; D008585:Meningitis, Meningococcal / Q000188:drug therapy / Q000453:epidemiology; D008589:Meningococcal Infections / Q000188:drug therapy / Q000453:epidemiology; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000453:epidemiology
D000900:Anti-Bacterial Agents