[Effect of leukotriene receptor antagonist on cough variant asthma].
OBJECTIVE
To study the curative effect of leukotriene receptor antagonist on cough variant asthma (CVA).


METHODS
Sixty-four CVA patients received treatment with bricany and montelukas and 68 control patients had bricany treatment for 4 weeks. The recurrence rate was observed in the two groups during the follow-up for 6 months.


RESULTS
The remission time of two groups were 2.5-/+3.6 and 5.3-/+3.8 days in acute phase, respectively, showing a significant difference between them (P<0.05). The recurrence rate of the two groups within 6 months were 20.09% and 40.87%, respectively, showing also significantly differences (P<0.05).


CONCLUSIONS
Leukotriene receptor antagonist and bricany can effectively control CVA and significantly lower the short-term recurrence rate of CVA.
He
Zhi-min
ZM
Department of Internal Medicine, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Guo
Yu-biao
YB
Xie
Can-mao
CM
D000328:Adult; D001249:Asthma / Q000150:complications* / Q000188:drug therapy; D016022:Case-Control Studies; D003371:Cough / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020024:Leukotriene Antagonists / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D018077:Receptors, Leukotriene / Q000378:metabolism*; D012008:Recurrence
D020024:Leukotriene Antagonists; D018077:Receptors, Leukotriene