title: Yeast strains for ethanol production from lignocellulosic hydrolysates during in situ detoxification.
abstract: Yeast strains Y1, Y4 and Y7 demonstrated high conversion efficiencies for sugars and high abilities to tolerate or metabolize inhibitors in dilute-acid lignocellulosic hydrolysates. Strains Y1 and Y4 completely consumed the glucose within 24 h in dilute-acid lignocellulosic hydrolysate during in situ detoxification, and the maximum ethanol yields reached 0.49 g and 0.45 g ethanol/g glucose, equivalent to maximum theoretical values of 96% and 88.2%, respectively. Strain Y1 could metabolize xylose to xylitol with a yield of 0.64 g/g xylose, whereas Y4 was unable to utilize xylose as a substrate. Strain Y7 was able to consume sugars (glucose and xylose) within 72 h during hydrolysate in situ detoxification, producing a high ethanol yield (equivalent to 93.6% of the maximum theoretical value). Y1 and Y7 are the most efficient yeast strains yet reported for producing ethanol from non-detoxified dilute-acid lignocellulosic hydrolysates. These findings offer huge potential for improving the economics of bio-ethanol production from lignocellulosic hydrolysates.
authors.affiliation: College of Life Science, Capital Normal University, Beijing, 100048, China.
authors.forename: Shen
authors.initials: S
authors.lastname: Tian
authors.forename: Guixiong
authors.initials: G
authors.lastname: Zhou
authors.forename: Fei
authors.initials: F
authors.lastname: Yan
authors.forename: Yong
authors.initials: Y
authors.lastname: Yu
authors.forename: Xiushan
authors.initials: X
authors.lastname: Yang
mesh_terms: D000431:Ethanol / Q000378:metabolism*; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000378:metabolism / Q000633:toxicity*; D005947:Glucose / Q000378:metabolism; D008031:Lignin / Q000378:metabolism; D014994:Xylose / Q000378:metabolism; D015003:Yeasts / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
chemical_list: C036909:lignocellulose; D000431:Ethanol; C008046:5-hydroxymethylfurfural; D008031:Lignin; D014994:Xylose; D005662:Furaldehyde; D005947:Glucose