The relationship between reproductive factors and metabolic syndrome in Korean postmenopausal women: Korea National Health and Nutrition Survey 2005.
OBJECTIVE
Postmenopausal women are known to have a higher prevalence of metabolic syndrome compared with premenopausal women. However, there are few studies that have investigated the effects of reproductive factors on metabolic syndrome in postmenopausal women. The objective of this study was to evaluate the association between reproductive factors and metabolic syndrome in postmenopausal women.


METHODS
A total of 892 postmenopausal women who participated in the 2005 Korean National Health and Nutrition Examination Survey were included. We determined an association between reproductive factors and metabolic syndrome.


RESULTS
Using a multivariate logistic regression analysis, it was found that age at first birth was negatively associated with metabolic syndrome. Having the first baby at a later age was associated with a decreased risk of having metabolic syndrome (odds ratio, 0.95; 95% CI, 0.90-0.99). However, other reproductive factors including age at menarche, age at menopause, parity, lifetime estrogen exposure, years since menopause, number of pregnancies, history of lactation, and oral contraceptives or hormone therapy use were not associated with metabolic syndrome.


CONCLUSIONS
Among various reproductive factors, age at first birth was negatively associated with metabolic syndrome in Korean postmenopausal women.
Cho
Geum Joon
GJ
Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea.
Park
Hyun Tae
HT
Shin
Jung Ho
JH
Kim
Tak
T
Hur
Jun Young
JY
Kim
Young Tae
YT
Lee
Kyu Wan
KW
Kim
Sun Haeng
SH
D000368:Aged; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D005260:Female; D020073:Gravidity / Q000502:physiology; D006306:Health Surveys; D006801:Humans; D007723:Korea / Q000453:epidemiology; D007774:Lactation / Q000502:physiology; D016015:Logistic Models; D008423:Maternal Age; D008572:Menarche / Q000502:physiology; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D008875:Middle Aged; D015999:Multivariate Analysis; D010298:Parity / Q000502:physiology; D017698:Postmenopause / Q000502:physiology*; D011247:Pregnancy; D015995:Prevalence; D017584:Reproductive History; D018570:Risk Assessment; D012307:Risk Factors