title: Administration regimens for sublingual immunotherapy to pollen allergens: what do we know?
abstract: The modalities of administration of sublingual immunotherapy (SLIT), including dosing, build-up phase, duration of the treatment, and frequency of the maintenance dose are largely variable. In the case of pollen (SLIT), the complexity increases, since preseasonal, coseasonal and pre-coseasonal regimens can be used. The administration regimens are of relevance from a practical point of view, but can also have economic implications. We review herein the available literature (randomized double blind controlled studies) on pollen SLIT, in order to derive experimentally-supported suggestions about the regimens of administration that should be preferred.
authors.affiliation: Pneumoallergology Unit, S. Orsola FBF Hospital, Brescia, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Lombardi
authors.forename: C
authors.initials: C
authors.lastname: Incorvaia
authors.forename: M
authors.initials: M
authors.lastname: Braga
authors.forename: G
authors.initials: G
authors.lastname: Senna
authors.forename: G W
authors.initials: GW
authors.lastname: Canonica
authors.forename: G
authors.initials: G
authors.lastname: Passalacqua
mesh_terms: D000286:Administration, Sublingual; D000485:Allergens / Q000008:administration & dosage* / Q000276:immunology; D003888:Desensitization, Immunologic / Q000379:methods*; D006801:Humans; D011058:Pollen / Q000276:immunology*
chemical_list: D000485:Allergens