title: Jaundice revealing a k light chain myeloma because of liver light chain deposits.
abstract: We report the case of a 77-year-old man referred for jaundice and diagnosed with intrahepatic light chain deposit as primary manifestation of a kappa light chain multiple myeloma. Jaundice is a very rare way of presentation for myeloma. In our observation, diagnosis was made by liver biopsy, which found light chain deposits infiltrating perisinusoidal spaces. We discuss jaundice's possible mechanisms in myeloma.
authors.affiliation: Department of Hepatogastroenterology, Rouen University Hospital, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Montialoux
authors.forename: Guillaume
authors.initials: G
authors.lastname: Savoye
authors.forename: Céline
authors.initials: C
authors.lastname: Savoye-Collet
authors.forename: Simon
authors.initials: S
authors.lastname: Ramirez
authors.forename: Arnaud
authors.initials: A
authors.lastname: François
authors.forename: Eric
authors.initials: E
authors.lastname: Lerebours
authors.forename: Odile
authors.initials: O
authors.lastname: Goria
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D007565:Jaundice / Q000209:etiology* / Q000473:pathology; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology
chemical_list: D007145:Immunoglobulin kappa-Chains