[Is end stage renal disease a poor prognosis factor of ischemic colitis?].
OBJECTIVE
In general, ischemic colitis has a very good prognosis. However, there are a lot of controversies in relation to the prognostic factors. The aim of this study was to evaluate risk factors of severe ischemic colitis.


METHODS
A retrospective study was undertaken of patients with ischemic colitis hospitalized at the Hanyang University Hospital during the interval 2004-2006. Patients were divided into two groups: those with mild course and those with severe course which led to operation, systemic inflammatory response syndrome, or death.


RESULTS
A total of 41 cases (M/F=13/28, mean age=63.8 years) of biopsy proven ischemic colitis were included, of which 31 (75.6%) had a mild course and 10 (24.4%) a severe course. Coexisting medical diseases of patients were hypertension (n=24), diabetes (n=14), end-stage renal disease (n=11), cardiovascular disease (n=5), and malignancy (n=5). Male (p=0.049), alcoholics (p=0.025), end-stage renal disease (p=0.013), LDH (p=0.002), CRP (p=0.014), and peritoneal irritation sign (p=0.001) were the significant risk factors of severe ischemic colitis in univariate analysis. In multivariate logistic regression analysis, end-stage renal disease (p=0.026) was the only significant risk factor of severe ischemic colitis.


CONCLUSIONS
Careful attention must be paid to end-stage renal disease patients having ischemic colitis.
Ahn
Sung Eun
SE
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Lee
Hang Lak
HL
Cho
Seung Chul
SC
Yoon
Jai Hoon
JH
Lee
Oh Young
OY
Yoon
Byung Chul
BC
Choi
Ho Soon
HS
Hahm
Joon Soo
JS
Lee
Min Ho
MH
Lee
Dong Hoo
DH
D000368:Aged; D017091:Colitis, Ischemic / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000175:diagnosis; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index