Grafting of molecularly imprinted polymers on iniferter-modified carbon nanotube.
Molecularly imprinted polymers (MIPs) were grafted on iniferter-modified carbon nanotube (CNT). Tween 20 was first immobilized on CNT by hydrophobic interactions. The hydroxyl-functionalized CNT was modified by silanisation with 3-chloropropyl trimethoxysilane. The iniferter groups were then introduced by reacting the CNT-bound chloropropyl groups with sodium N,N-diethyldithiocarbamate. UV light-initiated copolymerization of ethylene glycol dimethacrylate (crosslinking agent) and methacrylic acid (functional monomer) resulted in grafting of MIP on CNT for theophylline as a model template. MIPs grafted on CNT were characterized with elemental analysis, scanning electron microscopy, and thermogravimetric analysis. The theophylline-imprinted polymer on CNT showed higher binding capacity for theophylline than non-imprinted polymer on CNT and selectivity for theophylline over caffeine and theobromine (similar structure molecules). The data of theophylline and caffeine binding into the theophylline-imprinted polymer correlated well with the Scatchard plot. These MIPs on CNT can potentially be applied to probe materials in biosensor system based on CNT field effect transistor.
Lee
H-Y
HY
Department of Chemical Engineering, Chungbuk National University, 410 Seongbongro, Heungdeokgu, Cheongju, Chungbuk 361-763, Republic of Korea.
Kim
B S
BS
D001665:Binding Sites; D015374:Biosensing Techniques; D002110:Caffeine / Q000737:chemistry; D007700:Kinetics; D008855:Microscopy, Electron, Scanning; D054802:Molecular Imprinting / Q000379:methods*; D015394:Molecular Structure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D013805:Theobromine / Q000737:chemistry; D013806:Theophylline / Q000737:chemistry
D037742:Nanotubes, Carbon; D011108:Polymers; D002110:Caffeine; D013806:Theophylline; D013805:Theobromine