title: Dynamic contrast-enhanced breast MR imaging.
abstract: This article discusses the basic principles of dynamic contrast-enhanced MR imaging (DCE-MR imaging) of the breast, including technical parameters, image acquisition, and image interpretation. Clinical DCE-MR imaging of the breast has undergone considerable growth from a once investigational technique to an important clinical tool in widespread use. Progress in MR technology and refinement of MR imaging parameters now allow for concurrent acquisition of high-spatial-resolution and adequate-temporal-resolution images, which are necessary for accurate assessment of breast lesion morphology and qualitative kinetic analysis. More advanced DCE-MR imaging techniques involving higher-temporal-resolution images and rigorous quantitative analysis of the time signal enhancement curves are currently an area of research.
authors.affiliation: Department of Diagnostic Radiology, Yale New Haven Hospital, 333 Cedar Street, MRC-147, New Haven, CT 06520, USA. marianne.moon@yale.edu
authors.forename: Marianne
authors.initials: M
authors.lastname: Moon
authors.forename: Daniel
authors.initials: D
authors.lastname: Cornfeld
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Weinreb
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D005682:Gadolinium