title: Genome scan detects quantitative trait loci affecting female fertility traits in Danish and Swedish Holstein cattle.
abstract: Data from the joint Nordic breeding value prediction for Danish and Swedish Holstein grandsire families were used to locate quantitative trait loci (QTL) for female fertility traits in Danish and Swedish Holstein cattle. Up to 36 Holstein grandsires with over 2,000 sons were genotyped for 416 microsatellite markers. Single trait breeding values were used for 12 traits relating to female fertility and female reproductive disorders. Data were analyzed by least squares regression analysis within and across families. Twenty-six QTL were detected on 17 different chromosomes. The best evidence was found for QTL segregating on Bos taurus chromosome (BTA)1, BTA7, BTA10, and BTA26. On each of these chromosomes, several QTL were detected affecting more than one of the fertility traits investigated in this study. Evidence for segregation of additional QTL on BTA2, BTA9, and BTA24 was found.
authors.affiliation: Aarhus University, Faculty of Agricultural Sciences, Department of Genetics and Biotechnology, PO Box 50, 8830 Tjele, Denmark.
authors.forename: J K
authors.initials: JK
authors.lastname: Höglund
authors.forename: B
authors.initials: B
authors.lastname: Guldbrandtsen
authors.forename: G
authors.initials: G
authors.lastname: Su
authors.forename: B
authors.initials: B
authors.lastname: Thomsen
authors.forename: M S
authors.initials: MS
authors.lastname: Lund
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics / Q000502:physiology*; D003718:Denmark; D005260:Female; D005298:Fertility / Q000235:genetics*; D016678:Genome / Q000235:genetics*; D040641:Quantitative Trait Loci / Q000235:genetics*; D013548:Sweden