title: Platelet-rich plasma: new clinical application: a pilot study for treatment of jumper's knee.
abstract: This study describes a simple, low-cost, minimally invasive way to apply PRP growth factors to chronic patellar tendinosis; 20 male athletes with a mean history of 20.7 months of pain received treatment, and outcomes were prospectively evaluated at 6 months follow-up. No severe adverse events were observed, and statistically significant improvements in all scores were recorded. The results suggest that this method may be safely used for the treatment of jumper's knee, by aiding the regeneration of tissue which otherwise has low healing potential.
authors.affiliation: Biomechanics Laboratory, Department of Orthopaedic and Sports Trauma, Rizzoli Orthopaedic Institute, Via Di Barbiano 1/10, 40136 Bologna, Italy. e.kon@biomec.ior.it
authors.forename: Elizaveta
authors.initials: E
authors.lastname: Kon
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Filardo
authors.forename: Marco
authors.initials: M
authors.lastname: Delcogliano
authors.forename: Mirco Lo
authors.initials: ML
authors.lastname: Presti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Russo
authors.forename: Alice
authors.initials: A
authors.lastname: Bondi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Martino
authors.forename: Annarita
authors.initials: A
authors.lastname: Cenacchi
authors.forename: Pier Maria
authors.initials: PM
authors.lastname: Fornasari
authors.forename: Maurilio
authors.initials: M
authors.lastname: Marcacci
mesh_terms: D000293:Adolescent; D000328:Adult; D001265:Athletic Injuries / Q000628:therapy*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage*; D007718:Knee Injuries / Q000628:therapy; D008297:Male; D008875:Middle Aged; D017847:Patellar Ligament / Q000293:injuries; D010865:Pilot Projects; D015539:Platelet Activation; D053657:Platelet-Rich Plasma; D020127:Recovery of Function; D052256:Tendinopathy / Q000534:rehabilitation / Q000628:therapy*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects; D055815:Young Adult
chemical_list: D036341:Intercellular Signaling Peptides and Proteins