title: MotifAdjuster: a tool for computational reassessment of transcription factor binding site annotations.
abstract: Valuable binding-site annotation data are stored in databases. However, several types of errors can, and do, occur in the process of manually incorporating annotation data from the scientific literature into these databases. Here, we introduce MotifAdjuster http://dig.ipk-gatersleben.de/MotifAdjuster.html, a tool that helps to detect these errors, and we demonstrate its efficacy on public data sets.
authors.affiliation: Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben (IPK), Corrensstrasse 3, 06466 Gatersleben, Germany. Jens.Keilwagen@ipk-gatersleben.de
authors.forename: Jens
authors.initials: J
authors.lastname: Keilwagen
authors.forename: Jan
authors.initials: J
authors.lastname: Baumbach
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Kohl
authors.forename: Ivo
authors.initials: I
authors.lastname: Grosse
mesh_terms: D000465:Algorithms; D001665:Binding Sites; D019295:Computational Biology; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D030562:Databases, Protein; D004926:Escherichia coli / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000378:metabolism; D014157:Transcription Factors / Q000737:chemistry* / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D014157:Transcription Factors; C069780:NarL protein, E coli