Parathyroid hormone-related peptide and hypercalcaemia in a dog with functional keratinizing ameloblastoma.
This case report describes a 6-year-old dog with oral ameloblastoma and hypercalcaemia. Serum parathyroid hormone-related peptide (PTH-rp) levels were high. No other cause for hypercalcaemia was found. The hypercalcaemia resolved after hemimandibulectomy. We are not aware of the previous description of canine oral ameloblastoma and hypercalcaemia mediated by PTH-rp. This case report suggests that PTH-rp stimulation of the PTH receptor may result in hypercalcaemia in dogs with oral ameloblastoma or other odontogenic neoplasms.
Dhaliwal
R S
RS
All Care Animal Referral Center, Fountain Valley, CA 92708, USA. ravidvm@sbcglobal.net
Tang
K N
KN