[Antiphospholipid syndrome in the year 2009].
Antiphospholipid syndrome is a prothrombotic disorder characterized by vascular occlusions and/or pregnancy morbidity in the presence of antiphospholipid antibodies. These autoantibodies represent a large and heterogenous family of circulating immunoglobulins usually identified as anticardiolipin antibodies and antibodies directed against beta2-glykoprotein I or as lupus anticoagulant. A number of criteria for diagnosis of antiphospholipid syndrome have been proposed. In this review, we focused on long-term process of diagnostic procedures development and future directions in scientific research in this field.
Buliková
A
A
Oddelení klinické hematologie Fakultní nemocnice Bmrno. abulik@fnbrno.cz
Zavrelová
J
J
Penka
M
M
D000818:Animals; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000145:classification / Q000175:diagnosis; D035843:Biomedical Research; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000145:classification / Q000175:diagnosis