title: Unusual presentation of entomophthoromycosis.
abstract: Rhinoentomophthoromycosis caused by Conidiobolus sp commonly presents as a chronic granulomatous lesion that affects the rhinofacial subcutaneous tissue. We present an 18-year-old girl who presented with progressive bilateral proptosis and loss of vision since 2 weeks. Biopsy and fungal cultures confirmed diagnosis of Conidiobolus sp infection of the paranasal sinuses bilaterally with orbital extension and blindness. The clinical picture was complicated by the presence of sputum-positive cavitatory pulmonary tuberculosis, which was diagnosed at the same time. To our knowledge, this is the first such case to be reported from India. We also discuss the management of entomophthoromycosis. Despite many reports of success, there remains no consensus on the treatment of Conidiobolus infections of the nose and the paranasal sinuses with antifungal agents.
authors.affiliation: Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India. rajmike@hotmail.co.uk
authors.forename: R C
authors.initials: RC
authors.lastname: Michael
authors.forename: J S
authors.initials: JS
authors.lastname: Michael
authors.forename: M S
authors.initials: MS
authors.lastname: Mathews
authors.forename: V
authors.initials: V
authors.lastname: Rupa
mesh_terms: D000293:Adolescent; D001706:Biopsy; D020092:Conidiobolus / Q000302:isolation & purification*; D005260:Female; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D007194:India; D009668:Nose Diseases / Q000382:microbiology*; D009916:Orbital Diseases / Q000382:microbiology / Q000473:pathology; D010256:Paranasal Sinuses / Q000382:microbiology / Q000473:pathology; D011859:Radiography; D012867:Skin / Q000382:microbiology / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000150:complications; D020096:Zygomycosis / Q000175:diagnosis* / Q000473:pathology*