Protective effects of celery juice in treatments with Doxorubicin.
The aim of this work was to investigate possible protective effect of celery juice in doxorubicin treatment. The following biochemical parameters were determined: content of reduced glutathione, activities of catalase, xanthine oxidase, glutathione peroxidase, peroxidase, and lipid peroxidation intensity in liver homogenate and blood hemolysate. We examined influence of diluted pure celery leaves and roots juices and their combinations with doxorubicine on analyzed biochemical parameters. Celery roots and leaves juices influenced the examined biochemical parameters and showed protective effects when applied with doxorubicine.
Kolarovic
Jovanka
J
Institute for Child and Youth Health Care of Vojvodina, Department of Hematology/Oncology, Novi Sad, Republic of Serbia. popovic@ih.ns.ac.yu
Popovic
Mira
M
Mikov
Momir
M
Mitic
Radoslav
R
Gvozdenovic
Ljiljana
L
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D000077102:Apium / Q000033:anatomy & histology / Q000737:chemistry*; D001798:Blood Proteins / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D019610:Cytoprotection; D004317:Doxorubicin / Q000494:pharmacology / Q000633:toxicity; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D051379:Mice; D009195:Peroxidase / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D014969:Xanthine Oxidase / Q000378:metabolism
D000975:Antioxidants; D001798:Blood Proteins; D010936:Plant Extracts; D004317:Doxorubicin; D002374:Catalase; D009195:Peroxidase; D005979:Glutathione Peroxidase; D014969:Xanthine Oxidase; D005978:Glutathione