Design of hetero-bivalent polypeptides as kinetics-based sensors for high-sensitivity detection of weak molecular interactions.
Tonan
Kenji
K
Biomolecular NMR and Protein Research Group, Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal H4P2R2, Canada.
Tolkatchev
Dmitri
D
Xu
Ping
P
Wang
Ping
P
Plamondon
Josee
J
Vinogradova
Anna
A
Gingras
Richard
R
Ni
Feng
F
D000595:Amino Acid Sequence; D006801:Humans; D007700:Kinetics; D008969:Molecular Sequence Data; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013917:Thrombin / Q000737:chemistry
D010455:Peptides; D013917:Thrombin