Composite outcomes can distort the nature and magnitude of treatment benefits in clinical trials.
Ferreira-Gonzalez
Ignacio
I
Permanyer-Miralda
Gaieta
G
Busse
Jason W
JW
Devereaux
P J
PJ
Guyatt
Gordon H
GH
Alonso-Coello
Pablo
P
Montori
Victor M
VM
D035843:Biomedical Research / Q000379:methods; D003627:Data Interpretation, Statistical; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods* / Q000592:standards; D016896:Treatment Outcome