title: Differential effects of single versus double aortic clamping on myocardial protection during coronary bypass.
abstract: The effects of double (n = 60, group 1) versus single (n = 60, group 2) aortic clamping on myocardial function and protection were investigated during coronary artery bypass grafting using a heart-lung pump. In group 1, after opening the cross clamp, proximal anastomosis was completed using side clamps and, in group 2, distal and proximal anastomosis was completed with a single clamp. Cross clamping time in the single-clamp patients (group 2; 77.1 min) was significantly higher than in the double-clamp patients (group 1; 62.9 min). Troponin T was significantly higher in group 2 than in group 1 h and 24 h after surgery. Post-operative left ventricular ejection fraction decreased in both groups, but this was not statistically significant. Post-operative wall motion score index and myocardial performance index increased significantly in both groups compared with the pre-operative level. Overall, the double-clamp technique provided better myocardial protection than the single-clamp technique and neither technique seemed to have a negative impact on the early post-operative global functioning of the left ventricle, however the effect of these techniques on the global functioning of the left ventricle in the late postoperative period needs to be evaluated.
authors.affiliation: Cardiovascular Surgery, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey. osmantiryaki@gmail.com
authors.forename: O
authors.initials: O
authors.lastname: Tiryakioglu
authors.forename: U
authors.initials: U
authors.lastname: Sayar
authors.forename: S
authors.initials: S
authors.lastname: Demirtas
authors.forename: T
authors.initials: T
authors.lastname: Goncu
authors.forename: G
authors.initials: G
authors.lastname: Yumun
authors.forename: A
authors.initials: A
authors.lastname: Ozyazicioglu
mesh_terms: D001011:Aorta / Q000601:surgery*; D001831:Body Temperature; D003250:Constriction; D001026:Coronary Artery Bypass; D052279:Creatine Kinase, MB Form / Q000378:metabolism; D004452:Echocardiography; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology / Q000473:pathology*; D011182:Postoperative Care; D020107:Troponin T / Q000378:metabolism
chemical_list: D020107:Troponin T; D052279:Creatine Kinase, MB Form