Hypereosinophilic syndrome in childhood: clinical and molecular features of two cases.
Hypereosinophilic syndrome (HES) represents a heterogeneous group of diseases, some of which are being clarified by recent advances in molecular genetics. It is very rare in children. Uncertainties in classification and lack of prospective studies make therapeutic decisions difficult. The authors report two cases of HES in which steroid therapy was effective.
Farruggia
Piero
P
Pediatric Hematology & Oncology, G. Di Cristina Children's Hospital, Palermo, Italy. farruggia.oep@ospedalecivicopa.org
D'Angelo
Paolo
P
Acquaviva
Antonio
A
Trizzino
Antonino
A
Tucci
Fabio
F
Cilloni
Daniela
D
Messa
Francesca
F
D'Ambrosio
Alfonso
A
Aricò
Maurizio
M
D001856:Bone Marrow Examination; D002648:Child; D020732:Cytogenetic Analysis; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome
D013256:Steroids; D011241:Prednisone