title: [Thyroid gland in the gravidity].
abstract: OBJECTIVE
  Disorders of the thyroid gland are the most common endocrinopathies in the gravidity. The spectrum of thyroid diseases in the pregnancy is not different from the diseases that affect the thyroid outside this period of life. However, clinical manifestations of thyreopaties can be modified by gravidity. Some thyreopaties are associated with gravidity or post partum period, or become manifest in this periods for the first time. The aim of this study was to assess thyroidal status of healthy pregnant women without history or clinical signs of thyreopathy.
  
  
  METHODS
  One-time cross-sectional study.
  
  
  METHODS
  3rd internal clinic FNLP, Kosice.
  
  
  METHODS
  We examined 76 pregnant women (mean age 34.46 +/- 5.34 years). The protocol included medical history, physical examination and assessment of TSH, fT4 and anti-TPO concentrations.
  
  
  RESULTS
  The mean concentration of TSH was 2.78 +/- 1.25 mlU/ml. We found TSH concentration over 5.0 mlU/ml in 5 participants (6.58%), TSH levels in the borderline range between 4.0-5.0 mlU/ml had another 2 pregnants (2.63%). fT4 concentration was 15.02 +/- 3.61 pmol/l. The mean anti-TPO concentration was 43.28 +/- 15.75 IU/ml. 17 pregnant women (22%) had anti-TPO concentration over 25 IU/ml, which is the level that indicates autoimmune thyroiditis.
  
  
  CONCLUSIONS
  Thyreopathies are the most common endocrinopathies in the population and there is the evidence that almost one third of European population is affected from diseases of thyroid gland, predominantly women in fertile age. In the clinical praxis it is essential to think of thyroid disorders and in the case of need screening of the thyroid function.
authors.affiliation: III. interná klinika LF UPJS a FN LP, Kosice.
authors.forename: V
authors.initials: V
authors.lastname: Vargová
authors.forename: V
authors.initials: V
authors.lastname: Mechírová
authors.forename: M
authors.initials: M
authors.lastname: Pytliak
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007453:Iodide Peroxidase / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D013959:Thyroid Diseases / Q000175:diagnosis*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D007453:Iodide Peroxidase; D013974:Thyroxine