title: Completion pancreatectomy for treatment of a Clostridium perfringens pancreatic infection.
abstract: Pancreatic infection is associated with high morbidity and mortality. Drainage of the infection is the usual therapeutic approach. Clostridium perfringens infection can cause fulminant sepsis, but it rarely occurs within the pancreas. The case of a 76-year-old man with cystic pancreatic lesions in which sepsis developed after endoscopic ultrasound with fine-needle aspiration biopsy is described. The sepsis was managed with pancreatic resection and antibiotics. Clostridium perfringens was isolated from blood cultures and microbiologic smears from the pancreas. Invasive intraductal papillary mucinous neoplasm with lymph node involvement was identified on histologic examination. The patient made a complete recovery from surgery without complications.
authors.affiliation: Department of Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033-0850, USA.
authors.forename: Jovenel
authors.initials: J
authors.lastname: Cherenfant
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Nikfarjam
authors.forename: Abraham
authors.initials: A
authors.lastname: Mathew
authors.forename: Eric T
authors.initials: ET
authors.lastname: Kimchi
authors.forename: Kevin F
authors.initials: KF
authors.lastname: Staveley-O'Carroll
mesh_terms: D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle / Q000009:adverse effects; D021441:Carcinoma, Pancreatic Ductal / Q000150:complications / Q000601:surgery; D003015:Clostridium Infections / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D003016:Clostridium perfringens; D019160:Endosonography; D006801:Humans; D008297:Male; D010180:Pancreatectomy; D010181:Pancreatic Cyst / Q000175:diagnosis; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery; D010195:Pancreatitis / Q000209:etiology / Q000601:surgery*; D018805:Sepsis / Q000382:microbiology; D018084:Ultrasonography, Interventional