Clinical evaluation of severe asthma attacks requiring tracheal intubation and mechanical ventilation.
BACKGROUND
Although the number of patients requiring hospitalization due to asthma attacks has decreased over the years, there are many who still require hospitalization for tracheal intubation and mechanical ventilation following a severe asthma attack. Therefore, we evaluated the characteristics of patients with asthma who required tracheal intubation and mechanical ventilation in our hospital.


METHODS
We evaluated 20 patients who had severely exacerbated asthma, requiring tracheal intubation and mechanical ventilation. An evaluation was made based on their smoking history, the number of days from the onset of the asthma attack to admission, the level of asthma control, treatments before presenting to our hospital, the frequency of hospital visits, the reason for tracheal intubation and mechanical ventilation, and outcome.


RESULTS
Of the 20 patients with asthma 13 were men and 7 women, with a mean age of 48.7 years. The characteristics of patients who required tracheal intubation and mechanical ventilation were as follows: (1) smokers, (2) not taking or irregularly taking medication, (3) using inhaled short-acting beta(2)agonist (SABA) alone as needed, and (4) not using inhaled corticosteroids (ICS).


CONCLUSIONS
Our findings suggest that treatment mainly using ICS, in addition to increased awareness of the dangers of asthma among the patients themselves, are important in preventing severe asthma attacks requiring tracheal intubation and mechanical ventilation.
Sekiya
Kiyoshi
K
Department of Respiratory Medicine, Toho University Medical Center, Tokyo, Japan. k-sekiya@sagamihara-hosp.gr.jp
Sugino
Keishi
K
Hojyo
Takako
T
Ishida
Fumiaki
F
Sano
Go
G
Isobe
Kazunori
K
Kimura
Kazuhiro
K
Taniguchi
Masami
M
Akiyama
Kazuo
K
Homma
Sakae
S
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000553:Ambulatory Care / Q000706:statistics & numerical data; D001249:Asthma / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D004630:Emergencies; D005260:Female; D006801:Humans; D007239:Infections / Q000150:complications; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects; D014887:Weather; D055815:Young Adult; D016903:Drug Monitoring
D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists