A novel pedigree with heterozygous germline RUNX1 mutation causing familial MDS-related AML: can these families serve as a multistep model for leukemic transformation?
Ripperger
T
T
Steinemann
D
D
Göhring
G
G
Finke
J
J
Niemeyer
C M
CM
Strahm
B
B
Schlegelberger
B
B
D000293:Adolescent; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D005260:Female; D018095:Germ-Line Mutation; D006579:Heterozygote; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008954:Models, Biological; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000235:genetics*; D010375:Pedigree
D050676:Core Binding Factor Alpha 2 Subunit