Non-invasive optical mapping of the piglet brain in real time.
We have performed non-invasive, real-time optical mapping of the piglet brain during a subcortical injection of autologous blood. The time resolution of the optical maps is 192 ms, thus allowing us to generate a real-time video of the growing subcortical hematoma. The increased absorption at the site of blood injection is accompanied by a decreased absorption at the contralateral brain side. This contralateral decrease in the optical absorption and the corresponding time traces of the cerebral hemoglobin parameters are consistent with a reduced cerebral blood flow caused by the increased intracranial pressure.
Fantini
S
S
Franceschini
M
M
Gratton
E
E
Hueber
D
D
Rosenfeld
W
W
Maulik
D
D
Stubblefield
P
P
Stankovic
M
M