Endovenous microwave ablation of varicose veins: in vitro, live swine model, and clinical study.
OBJECTIVE
This study aims to investigate the application of the microwave generator to treat the patients with varicose veins.


METHODS
Phase 1: Explanted saphenous veins in subcutaneous layer of the pork meat were ablated at 0, 40, 50, 60, and 70 W. Phase 2: The forelimb veins and the hindlimb arteries of a 40-kg swine were ablated at 50 and 60 W. Phase 3: The patients were treated with endovenous microwave ablation at 50 W.


RESULTS
Phase 1: Perivenous tissue injury was found in groups 50, 60, and 70 W. Phase 2: Less perivenous tissue injury was found in group 50 W. Phase 3: Complete venous occlusion rate was 65% and venous reflux-free was 85% in 1 year. No severe complication was found.


CONCLUSIONS
The microwave generator with 50-W power setting could be used to ablate the varicose veins safely.
Subwongcharoen
Somboon
S
Department of Surgery, Rajavithi Hospital, Phayathai, Bangkok, Thailand. somboonsub@hotmail.com
Praditphol
Nipon
N
Chitwiset
Seksan
S
D000818:Animals; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D012501:Saphenous Vein / Q000473:pathology / Q000601:surgery*; D013552:Swine