title: [Preparation of patients on anticoagulant treatment for invasive surgery].
abstract: The management of warfarin therapy in patients undergoing surgery or other invasive procedures involves a balance between the risk of hemorrhage, and the risk of thrombosis. Risk of hemorrhage and the trombosis depends on the type of procedure and on pre-existing conditions. Procedures with low risk of hemorrhage (dental, dermatologic or ophtalmologic procedures, endoscopy) can be provided with continuing anticoagulant therapy. Surgery with high hemorrhagic risk need stop warfarin and start bridging anticoagulant therapy, such as unfractionated heparin or low molecular weight heparin, prior and after surgery. In patients requiring emergency surgery, vitamin K, prothrombin complex concentrate or fresh frozen plasma can be used to improve coagulation.
authors.affiliation: Hematologické oddelení, Onkologické centrum J. G. Mendela Nový Jicín. martin.brejcha@onkologickecentrum.cz
authors.forename: M
authors.initials: M
authors.lastname: Brejcha
authors.forename: J
authors.initials: J
authors.lastname: Gumulec
authors.forename: M
authors.initials: M
authors.lastname: Penka
authors.forename: D
authors.initials: D
authors.lastname: Klodová
authors.forename: M
authors.initials: M
authors.lastname: Wróbel
authors.forename: E
authors.initials: E
authors.lastname: Bogoczová
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D004630:Emergencies; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D019990:Perioperative Care; D011300:Preoperative Care; D012307:Risk Factors; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D014859:Warfarin