VEGF/KDR loop is a target of AG1296 in acute myeloid leukaemia showing FLT3-internal tandem duplications.
Torres
Luis Arístides
LA
Barbarroja
Nuria
N
Dorado
Gabriel
G
Velasco
Francisco
F
López-Pedrera
Chary
C
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics*; D020080:Tandem Repeat Sequences; D020032:Tyrphostins / Q000627:therapeutic use*; D040301:Vascular Endothelial Growth Factor Receptor-2 / Q000378:metabolism*
D000970:Antineoplastic Agents; D008565:Membrane Proteins; D020032:Tyrphostins; C084881:flt3 ligand protein; C106250:6,7-dimethoxy-3-phenylquinoxaline; D040301:Vascular Endothelial Growth Factor Receptor-2