title: Neonatal ventilators: how do they differ?
abstract: Remarkable technological advances over the past two decades have brought dramatic changes to the neonatal intensive care unit. Microprocessor-based mechanical ventilation has replaced time-cycled, pressure-limited, intermittent mandatory ventilation with almost limitless options for the management of respiratory failure in the prematurely born infant. Unfortunately, much of the infusion of technology occurred before the establishment of a convincing evidence base. This review focuses on the basic principles of mechanical ventilation, nomenclature and the characteristics of both conventional and high-frequency devices.
authors.affiliation: Department of Pediatrics, Division of Neonatal-Perinatal Medicine, CS Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI 48109-0254, USA. smdonnmd@med.umich.edu
authors.forename: S M
authors.initials: SM
authors.lastname: Donn
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000503:physiopathology / Q000517:prevention & control; D002986:Clinical Trials as Topic; D004867:Equipment Design; D019317:Evidence-Based Medicine; D006801:Humans; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood; D011030:Pneumothorax / Q000503:physiopathology / Q000517:prevention & control; D012121:Respiration, Artificial / Q000145:classification / Q000295:instrumentation* / Q000379:methods; D012127:Respiratory Distress Syndrome, Newborn / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D015996:Survival Rate; D013813:Therapy, Computer-Assisted; D013990:Tidal Volume / Q000502:physiology; D016896:Treatment Outcome; D015300:Ventilator Weaning
chemical_list: D010100:Oxygen