title: Reliability of the Vitek 2 yeast susceptibility test for detection of in vitro resistance to fluconazole and voriconazole in clinical isolates of Candida albicans and Candida glabrata.
abstract: The Vitek 2 yeast susceptibility test was evaluated by testing 122 Candida isolates against fluconazole and voriconazole. Excellent categorical agreement with the CLSI broth microdilution method was observed (97.5% for both the azoles). Moreover, the Vitek 2 system was able to identify all but 2 of 59 investigated fluconazole-resistant organisms.
authors.affiliation: Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Largo F. Vito, 1 00168 Rome, Italy.
authors.forename: Brunella
authors.initials: B
authors.lastname: Posteraro
authors.forename: Rosa
authors.initials: R
authors.lastname: Martucci
authors.forename: Marilena
authors.initials: M
authors.lastname: La Sorda
authors.forename: Barbara
authors.initials: B
authors.lastname: Fiori
authors.forename: Dominique
authors.initials: D
authors.lastname: Sanglard
authors.forename: Elena
authors.initials: E
authors.lastname: De Carolis
authors.forename: Ada Rita
authors.initials: AR
authors.lastname: Florio
authors.forename: Giovanni
authors.initials: G
authors.lastname: Fadda
authors.forename: Maurizio
authors.initials: M
authors.lastname: Sanguinetti
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000302:isolation & purification; D041221:Candida glabrata / Q000187:drug effects* / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D011743:Pyrimidines / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D015725:Fluconazole; D065819:Voriconazole