Cardiovascular translational medicine (IV): The genetic basis of malignant arrhythmias and cardiomyopathies.
The remarkable advances that have taken place in biomedicine over the past 50 years have resulted in dramatic improvements in the prevention, diagnosis and treatment of many diseases. Although cardiology has adopted these advances at a relatively slow pace, today it is fully immersed in this revolution and has become one of the most innovative medical specialties. Research is continuing to give rise to new developments in genetics and molecular biology that lead, almost daily, to innovative ways of preventing, diagnosing and treating the most severe forms of heart disease. Consequently, it is essential that clinical cardiologists have some basic knowledge of genetics and molecular biology as these disciplines are having an increasing influence on clinical practice.
Campuzano
Oscar
O
Centre de Genètica Cardiovascular, Universitat de Girona, Girona 08036, Spain.
Sarquella-Brugada
Georgia
G
Brugada
Ramon
R
Brugada
Pedro
P
Brugada
Josep
J
D001145:Arrhythmias, Cardiac / Q000235:genetics* / Q000503:physiopathology; D015220:Calcium Channels / Q000235:genetics / Q000502:physiology; D009202:Cardiomyopathies / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D007473:Ion Channels / Q000235:genetics / Q000502:physiology; D015221:Potassium Channels / Q000235:genetics / Q000502:physiology
D015220:Calcium Channels; D007473:Ion Channels; D015221:Potassium Channels