title: Effect of routine cardiovascular catheterization on cardiac troponin I concentration in dogs.
abstract: OBJECTIVE
  To determine changes in cardiac troponin I concentration (cTnI) associated with cardiovascular catheterization in dogs.
  
  
  METHODS
  cTnI was measured after transarterial coil embolization of patent ductus arteriosus (PDA), balloon valvuloplasty (BV), and pacemaker implantation (PACE). Dogs undergoing ovariohysterectomy (OHE) were used as a control, with 15 animals in each group. Blood for the cTnI assay was collected at baseline (T0), at 5h (T5), 24h (T24) and 10 days (T240) post-procedure. The effects of age, duration and difficulty of the procedure were evaluated.
  
  
  RESULTS
  There was no difference in cTnI concentration at T0 for any of the groups. There was a significant increase in cTnI concentration for BV and PACE, but not PDA at T5 and T24. PACE at T24 and T240 also had higher cTnI than control. Dogs with longer procedure times had significantly higher concentration of cTnI. There was no correlation between the difficulty of the procedure or peri-procedure complications and cTnI.
  
  
  CONCLUSIONS
  cTnI increased during some cardiovascular catheterization procedures, but returned to normal values at 24-240 h. Patients undergoing long catheterization procedures have increased risk for myocardial injury, but this was not related to short-term prognosis.
authors.affiliation: College of Veterinary Medicine, University of Florida, PO Box 100136, Gainesville, Fl 32610-0136, USA. shiha@vetmed.ufl.edu
authors.forename: Andre C
authors.initials: AC
authors.lastname: Shih
authors.forename: Herbert W
authors.initials: HW
authors.lastname: Maisenbacher
authors.forename: Agda
authors.initials: A
authors.lastname: Barreirinha
authors.forename: Darcy B
authors.initials: DB
authors.lastname: Adin
authors.forename: Mandi K
authors.initials: MK
authors.lastname: Schmidt
authors.forename: Robert
authors.initials: R
authors.lastname: Prosek
authors.forename: Amara H
authors.initials: AH
authors.lastname: Estrada
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000662:veterinary*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000662:veterinary*; D002404:Catheterization / Q000009:adverse effects / Q000662:veterinary; D004283:Dog Diseases / Q000097:blood* / Q000628:therapy; D004285:Dogs; D004374:Ductus Arteriosus, Patent / Q000097:blood / Q000628:therapy / Q000662:veterinary; D005260:Female; D008297:Male; D010138:Pacemaker, Artificial / Q000009:adverse effects / Q000662:veterinary; D011183:Postoperative Complications / Q000097:blood / Q000662:veterinary*; D019919:Prosthesis Implantation / Q000662:veterinary; D018570:Risk Assessment; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I