title: Synthesis of gamma-nitro aliphatic methyl esters via Michael additions promoted by microwave irradiation.
abstract: A simple and efficient protocol has been developed for the direct synthesis of gamma-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions.
authors.affiliation: Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos. Cuernavaca, Mor., Mexico. jaime@ciq.uaem.mx
authors.forename: Jaime
authors.initials: J
authors.lastname: Escalante
authors.forename: Francisco D
authors.initials: FD
authors.lastname: Díaz-Coutiño
mesh_terms: D002087:Butyrates / Q000138:chemical synthesis / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure
chemical_list: D002087:Butyrates; D004952:Esters