Thrombolytics for hyperacute stroke in children.
Intravenous tissue plasminogen activator (tPA) has changed the landscape of acute stroke care in adults, but remains unstudied in children. Developmental differences in both stroke etiologies and the hematologic system may alter the risk benefit ratio of this drug when applied to stroke in children.
Amlie-Lefond
Catherine
C
Department of Neurology, Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, Wisconsin, USA.
Fullerton
Heather J
HJ
D000208:Acute Disease; D002648:Child; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator