title: Reference values for continuous glucose monitoring in Chinese subjects.
abstract: OBJECTIVE
  The widespread clinical application of continuous glucose monitoring (CGM) is limited by the lack of generally accepted reference values. This multicenter study aims to establish preliminary normal reference values for CGM parameters in a sample of healthy Chinese subjects.
  
  
  METHODS
  A total of 434 healthy individuals with normal glucose regulation completed a 3-day period of glucose monitoring using a CGM system. The 24-h mean blood glucose (24-h MBG) and the percentage of time that subjects' blood glucose levels were >or=140 mg/dl (PT140) and <or=70 mg/dl (PT70) within 24 h were analyzed.
  
  
  RESULTS
  There was excellent compliance of finger stick blood glucose values with CGM measurements for subjects. Among the 434 subjects, the daily blood glucose varied from 76.9 +/- 11.3 to 144.2 +/- 23.2 mg/dl. The 24-h MBG, PT140, and PT70 were 104 +/- 10 mg/dl, 4.1 +/- 5.8%, and 2.4 +/- 5.3%, respectively. As for these parameters, no significant differences were found between men and women. The 95th percentile values were adopted as the upper limits of CGM parameters, which revealed 119 mg/dl (6.6 mmol/l) for 24-h MBG, 17.1% for PT140, and 11.7% for PT70.
  
  
  CONCLUSIONS
  We recommend a 24-h MBG value <119 mg/dl, PT140 <17% (4 h), and PT70 <12% (3 h) as normal ranges for the Chinese population.
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.forename: Xingwu
authors.initials: X
authors.lastname: Ran
authors.forename: Wenying
authors.initials: W
authors.lastname: Yang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.forename: Yongde
authors.initials: Y
authors.lastname: Peng
authors.forename: Yanbing
authors.initials: Y
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Gao
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Luan
authors.forename: Weiqing
authors.initials: W
authors.lastname: Wang
authors.forename: Weiping
authors.initials: W
authors.lastname: Jia
mesh_terms: D000328:Adult; D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism*; D001794:Blood Pressure; D002681:China; D002784:Cholesterol / Q000097:blood; D004435:Eating / Q000502:physiology; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000379:methods*; D010349:Patient Compliance; D012016:Reference Values
chemical_list: D001786:Blood Glucose; D002784:Cholesterol