title: A case report with type II pleuropulmonary blastoma: successful treatment with surgery and chemotherapy.
abstract: Pleuropulmonary blastoma (PPB) is a very rare intrathoracic malignancy in childhood. It is an aggressive embryonal or blastemic neoplasm usually occurring in children younger than five years of age. PPB is treated with aggressive multimodal therapies consisting of surgery and chemotherapy. We present a case with PPB type II successfully treated with complete surgical resection following neoadjuvant chemotherapy. She has been free of disease for 33 months of follow-up. Complete surgical resection of the tumor at the time of diagnosis is the cornerstone of PPB management, but in the majority of patients, initial surgery is incomplete because a large tumor may involve vital structures. For this reason, patients with initially unresectable tumors should be treated with neoadjuvant chemotherapy to reduce the lesion to the point that it becomes resectable.
authors.affiliation: Department of Pediatrics, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Corapçioğlu
authors.forename: Tuba
authors.initials: T
authors.lastname: Liman
authors.forename: Görkem
authors.initials: G
authors.lastname: Aksu
authors.forename: Nagihan
authors.initials: N
authors.lastname: Inan
authors.forename: Murat
authors.initials: M
authors.lastname: Deveci
authors.forename: Yeşim
authors.initials: Y
authors.lastname: Gürbüz
authors.forename: Salih
authors.initials: S
authors.lastname: Topçu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D018202:Pulmonary Blastoma / Q000188:drug therapy / Q000601:surgery*