[A case report of FOLFOX treatment for primary duodenal carcinoma with multiple liver metastases].
We report a case of a woman in her sixties having primary duodenal carcinoma with multiple liver metastases who was treated with oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin(FOLFOX regimen). After completing 2 courses of the chemotherapy, computed tomography showed a partial response without any severe adverse events. Now at 8 months, the PR stage has been maintained. So far, no standard therapeutic strategy for metastatic duodenal carcinoma has been developed. However, we suggest a FOLFOX regimen can be highly effective as a safe approach for continuously maintaining the quality of life of patients with this rare type of cancer.
Fujiwara
Yasuhiro
Y
Department of Gastroenterological Surgery, Transplant, and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.
Naomoto
Yoshio
Y
Tanabe
Shunsuke
S
Sakurama
Kazufumi
K
Noma
Kazuhiro
K
Nishikawa
Toshio
T
Motoki
Takayuki
T
Takaoka
Munenori
M
Shirakawa
Yasuhiro
Y
Yamatsuji
Tomoki
T
Matsuoka
Junji
J
Tanaka
Noriaki
N
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D004379:Duodenal Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology*; D004384:Duodenoscopy; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000556:secondary*; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor; D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil