title: Acceptance of major surgical procedures and quality of life among long-term survivors of advanced head and neck cancer.
abstract: OBJECTIVE
  To evaluate the acceptance of major surgical procedures and quality of life among long-term survivors of advanced head and neck cancer treated at a single institution.
  
  
  METHODS
  Cross-sectional analysis of a consecutive series of patients.
  
  
  METHODS
  Tertiary care cancer center.
  
  
  METHODS
  Participants had advanced (T3 and T4) head and neck cancer, had undergone a surgical procedure with or without postoperative radiotherapy, and had a minimum disease-free survival duration of 1 year. Eligible participants completed a questionnaire about their attitudes toward long-term outcomes and the University of Washington Quality of Life Questionnaire (UW-QOL).
  
  
  METHODS
  Descriptive analyses of the results and comparisons of the scores for each UW-QOL domain.
  
  
  RESULTS
  A total of 273 patients were included in the study. Most were men (74.4%), with a median age of 56 years. The tumor site was the oral cavity in 101 patients (37.0%), larynx in 91 (33.3%), oropharynx in 64 (23.4%), and hypopharynx in 17 (6.2%). There were 167 patients (61.2%) with T3 tumors and 106 (38.8%) with T4 tumors. Adjuvant radiotherapy was performed in 153 patients (56.0%). Global quality of life was considered good to excellent by 162 patients (59.3%), and the mean UW-QOL composite score was 79.3. Most patients (91.2%) reported that they would undergo the same treatment if they had it to do again, and 95.6% reported that they would not like to exchange their present outcome for another treatment option with a lower chance of cure but with a possibly improved quality of life.
  
  
  CONCLUSIONS
  In this series, the vast majority of patients considered a radical surgical procedure an acceptable treatment and reported a good quality of life.
authors.affiliation: Department of Head and Neck Surgery and Otorhinolaryngology, Hospital A. C. Camargo, Rua Professor Antonio Prudente, 211-01509-900, São Paulo, Brazil. jgvartanian@uol.com.br
authors.forename: José Guilherme
authors.initials: JG
authors.lastname: Vartanian
authors.forename: Luiz Paulo
authors.initials: LP
authors.lastname: Kowalski
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D001938:Brazil; D003430:Cross-Sectional Studies; D018572:Disease-Free Survival; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D017060:Patient Satisfaction; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D012737:Sex Factors; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*; D055815:Young Adult