title: Symptoms during ATP-test under pacing: impact on syncope recurrence and prediction from the ATP-test without pacing.
abstract: Syncope recurrence in patients with positive ATP-test who underwent permanent pacemaker implantation is suspected to be related to vagal vasodilatation. We studied symptoms during ATP-test in 38 temporary paced patients. Among patients with positive ATP-test who underwent permanent pacemaker implantation (N = 14), the only one patient who recurred during follow-up was symptomatic during the initial paced ATP-test. Symptoms during paced ATP-test were well predicted by a higher blood pressure (BP) drop during standard ATP-test (i.e. without pacing) (Area under ROC curves > 0.70 for all BP parameters except for relative diastolic BP drop). Moreover, BP drop during standard and paced ATP-test were significantly correlated (all p ≤ 0.03). Thus, a higher BP drop measured during ATP-test without pacing might help identify patients who would experience recurrences due to vasodilatation under permanent pacing.
authors.forename: N
authors.initials: N
authors.lastname: Girerd
authors.forename: D
authors.initials: D
authors.lastname: Flammang
mesh_terms: D000255:Adenosine Triphosphate; D000368:Aged; D000369:Aged, 80 and over; D002304:Cardiac Pacing, Artificial / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012008:Recurrence; D013575:Syncope / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology
chemical_list: D000255:Adenosine Triphosphate