Resumption of ovarian function 20 years after chemotherapy-induced ovarian failure: a case report.
OBJECTIVE
To describe a case of resumption of ovarian function 20 years after chemotherapy-induced ovarian failure.


METHODS
Case report.


METHODS
University teaching hospital.


METHODS
A 33-year-old nulliparous black woman.


METHODS
Progesterone challenge, transvaginal ultrasound (TVS).


METHODS
Estradiol and FSH hormone levels.


RESULTS
Confirmation that ovarian function returned in a women who presented with cyclic vaginal bleeding after a 20-year history of amenorrhea secondary to chemotherapy-induced ovarian failure.


CONCLUSIONS
Return of ovarian function is possible after prolonged periods in women with chemotherapy-induced ovarian failure.
Longway
Megin
M
School of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
Matthews
Catherine A
CA
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008572:Menarche; D010053:Ovary / Q000473:pathology* / Q000502:physiology; D010060:Ovulation / Q000187:drug effects / Q000502:physiology*; D016649:Primary Ovarian Insufficiency / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology*; D012016:Reference Values
D000970:Antineoplastic Agents; D004958:Estradiol; D005640:Follicle Stimulating Hormone