Jaundice revealing a k light chain myeloma because of liver light chain deposits.
We report the case of a 77-year-old man referred for jaundice and diagnosed with intrahepatic light chain deposit as primary manifestation of a kappa light chain multiple myeloma. Jaundice is a very rare way of presentation for myeloma. In our observation, diagnosis was made by liver biopsy, which found light chain deposits infiltrating perisinusoidal spaces. We discuss jaundice's possible mechanisms in myeloma.
Montialoux
Hélène
H
Department of Hepatogastroenterology, Rouen University Hospital, France.
Savoye
Guillaume
G
Savoye-Collet
Céline
C
Ramirez
Simon
S
François
Arnaud
A
Lerebours
Eric
E
Goria
Odile
O
D000368:Aged; D017809:Fatal Outcome; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D007565:Jaundice / Q000209:etiology* / Q000473:pathology; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology
D007145:Immunoglobulin kappa-Chains