Erosive arthropathy with osteolysis as a typical feature in polyfibromatosis syndrome: a case report and a review of the literature.
Polyfibromatosis syndrome is a rare disease entity that is characterized by various clinical features such as palmar, plantar, and penile fibromatoses, keloid formations of the skin, and erosive arthropathy. Its precise pathophysiology or etiology remains unclear. In addition to distinctive diverse skin manifestations, patients with polyfibromatosis have been previously reported to show erosive arthropathy with significant limitation of movement at affected joints. However, the presence of erosive polyarthropathy in polyfibromatosis has not emphasized in previous cases. Here, we report a case of polyfibromatosis syndrome combined with painless massive structural destruction of hand and foot joints, and review the characteristics of erosive arthropathy in previous cases.
Kim
Seong-Kyu
SK
Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
Kim
Hyung Joon
HJ
Lee
Young Hwan
YH
Suh
Kyung Jin
KJ
Park
Sung-Hoon
SH
Choe
Jung-Yoon
JY
D000328:Adult; D001175:Arthrography; D003937:Diagnosis, Differential; D005350:Fibroma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D033023:Foot Joints / Q000000981:diagnostic imaging / Q000473:pathology; D050823:Hand Joints / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging / Q000473:pathology; D010014:Osteolysis / Q000175:diagnosis* / Q000209:etiology