Inter- and intramolecular photochemical reactions of fleroxacin.
In the cation formed by photoinduced C-F bond cleavage in fleroxacin, intramolecular reaction with the N-ethyl chain is prevented by the electron-withdrawing effect of fluorine and intermolecular attack by nucleophiles is facilitated.
Fasani
Elisa
E
Department of Organic Chemistry, University of Pavia, v. Taramelli 10, 27100 Pavia, Italy. elisa.fasani@unipv.it
Monti
Sandra
S
Manet
Ilse
I
Tilocca
Fedele
F
Pretali
Luca
L
Mella
Mariella
M
Albini
Angelo
A
D016576:Fleroxacin / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010777:Photochemistry
D016576:Fleroxacin