title: [Multifocal manifestation of Rosai-Dorfman disease. A rare case of purely extranodal sinus histiocytosis in the elderly].
abstract: Rosai-Dorfman disease belongs to the group of childhood histiocytoses and was initially described as sinus histiocytosis with massive lymphadenopathy. Its rare purely extranodal manifestation is primarily found in the head and neck region. An atypical primary manifestation in an elderly patient with multifocal extranodal disease is described, and this pathological entity is reviewed. Specific difficulties concerning differential diagnostic aspects as well as individually appropriate treatment strategies are discussed.
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf-, Hals- und plastische Gesichtschirurgie, Klinikum Darmstadt, Heidelberger Landstrasse 379, 64297, Darmstadt. Ingo.Ott@klinikum-darmstadt.de
authors.forename: I
authors.initials: I
authors.lastname: Ott
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: S
authors.initials: S
authors.lastname: Gattenlöhner
authors.forename: K
authors.initials: K
authors.lastname: Schwager
authors.forename: R
authors.initials: R
authors.lastname: Hagen
authors.forename: G
authors.initials: G
authors.lastname: Baier
mesh_terms: D000368:Aged; D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D035583:Rare Diseases / Q000175:diagnosis / Q000628:therapy