title: Correlation between clinical parameters and health-related quality of life in women with COPD.
abstract: OBJECTIVE
  To correlate health-related quality of life (HRQL) of women with COPD with clinical parameters and with the six-minute walk distance (6MWD; six-minute walk test).
  
  
  METHODS
  Cross-sectional study involving 30 female patients diagnosed with mild or moderate COPD treated at the Respiratory Outpatient Clinic of the Presidente Dutra University Hospital. Patients completed the Saint George's Respiratory Questionnaire (SGRQ) and were evaluated in terms of respiratory pressures, spirometry parameters and 6MWD. Descriptive statistical analysis was carried out, as were Student's t-tests for dependent variables, together with Pearson's and Spearman's correlation coefficients for numerical and ordinal variables, respectively.
  
  
  RESULTS
  According to the SGRQ total scores, HRQL was impaired, to some extent, in most of the participants. Most SGRQ total scores were between the second and the third quartiles, reflecting poor HRQL. The participants also presented poor functional capacity. Mean 6MWD (317.7 m), inspiratory muscle strength (-53.48 cmH2O) and expiratory muscle strength (69.5 cmH2O) were all below reference values. We found that HRQL was not correlated with body mass index or pulmonary function. However, HRQL presented a negative linear correlation with age, MIP and 6MWD, as well as a positive correlation with the sensation of dyspnea and fatigue.
  
  
  CONCLUSIONS
  In this study, HRQL, determined using the SGRQ, was severely impaired in COPD patients, who presented severe limitations in functional capacity, breath control and personal life.
authors.affiliation: Faculdade Santa Terezinha, São Luis, MA, Brasil. niltonlama@yahoo.com.br
authors.forename: Nilton Maciel
authors.initials: NM
authors.lastname: Mangueira
authors.forename: Isabel Lucena
authors.initials: IL
authors.lastname: Viega
authors.forename: Melissa de Almeida Melo Maciel
authors.initials: Mde A
authors.lastname: Mangueira
authors.forename: Alcimar Nunes
authors.initials: AN
authors.lastname: Pinheiro
authors.forename: Maria do Rosário da Silva Ramos
authors.initials: Mdo R
authors.lastname: Costa
mesh_terms: D000368:Aged; D004417:Dyspnea / Q000175:diagnosis; D004812:Epidemiologic Methods; D005080:Exercise Test; D005221:Fatigue / Q000175:diagnosis; D005260:Female; D006304:Health Status; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011788:Quality of Life; D013147:Spirometry; D016138:Walking