title: Primary osteosarcoma of ovary.
abstract: Primary osteosarcoma originating from the ovary is an exceedingly rare, highly malignant tumor. Only a few cases have been reported in the past few decades. We describe a 50-year-old postmenopausal woman who presented with a large abdominal mass. The clinical diagnosis was malignant ovarian cancer. Her disease was aggressive; she had no response to systemic chemotherapy and died within 1 month of presentation. A definitive diagnosis of primary ovarian osteosarcoma was made by histopathological examination of autopsy specimens. Although rare, primary ovarian osteosarcoma should be considered in the differential diagnosis of a large, rapidly progressing pelvic mass in a postmenopausal woman. Early diagnosis provides hope of a complete surgical resection, which is currently the only promising treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Shimane University School of Medicine, 89-1 Enyacho, Izumo, Shimane, 693-8501, Japan.
authors.forename: Shamima
authors.initials: S
authors.lastname: Yeasmin
authors.forename: Kentaro
authors.initials: K
authors.lastname: Nakayama
authors.forename: Masako
authors.initials: M
authors.lastname: Ishibashi
authors.forename: Atsuko
authors.initials: A
authors.lastname: Katagiri
authors.forename: Kouji
authors.initials: K
authors.lastname: Iida
authors.forename: Atsushi
authors.initials: A
authors.lastname: Manabe
authors.forename: Toru
authors.initials: T
authors.lastname: Nabika
authors.forename: Naomi
authors.initials: N
authors.lastname: Nakayama
authors.forename: Kohji
authors.initials: K
authors.lastname: Miyazaki
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*