title: A new and novel treatment of opioid dependence: Nigella sativa 500 mg.
abstract: BACKGROUND
  Opioid dependence is one of the major social and psychiatric problem of society. Unfortunately there is no non opiate treatment available. For centuries man has used plants for their healing proprieties. These plants play a fundamental part in all treatment modalities, both ancient and modern.
  
  
  METHODS
  This study was conducted to find non opiate treatment for opiate withdrawal. Total 35 known addicts of opiates were included in the study. This study was based on DSM IV criteria for opioid dependence.
  
  
  RESULTS
  This study demonstrates that non opioid treatment for opioid addiction decreases the withdrawal effects significantly. It further demonstrates that there are no changes in physiological parameters of subjects during treatment (BP, Pulse rate etc.). There is increased appetite but no significant weight gain in the subjects.
  
  
  CONCLUSIONS
  Non opioid drug Nigella sativa is effective in long-term treatment of opioid dependence. It not merely cures the opioid dependence but also cures the infections and weakness from which majority of addicts suffer.
authors.affiliation: Department of Pharmacology, Fatima Jinnah Dental College, Karachi.
authors.forename: Sibghatullah
authors.initials: S
authors.lastname: Sangi
authors.forename: Shahida P
authors.initials: SP
authors.lastname: Ahmed
authors.forename: Muhammad Aslam
authors.initials: MA
authors.lastname: Channa
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ashfaq
authors.forename: Shah Murad
authors.initials: SM
authors.lastname: Mastoi
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D031881:Nigella sativa; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D000701:Analgesics, Opioid; D010936:Plant Extracts