Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin-4 receptor polymorphisms identified in obese humans.
Haskell-Luevano
Carrie
C
Department of Medicinal Chemistry, University of Florida, Gainesville, FL 32610, USA.
Xiang
Zhimin
Z
Wilczynski
Andrzej M
AM
Haskell
Kimberly R
KR
Andreasen
Amy M
AM
Litherland
Sally A
SA
Millard
William J
WJ
Pogozheva
Ira D
ID
Mosberg
Henry I
HI
Sorenson
Nicholas B
NB
D006801:Humans; D008024:Ligands; D009765:Obesity / Q000235:genetics*; D011110:Polymorphism, Genetic; D044105:Receptor, Melanocortin, Type 4 / Q000819:agonists* / Q000235:genetics
D008024:Ligands; D044105:Receptor, Melanocortin, Type 4