Articular cartilage tissue engineering: today's research, tomorrow's practice?
Articular cartilage repair remains a challenge to surgeons and basic scientists. The field of tissue engineering allows the simultaneous use of material scaffolds, cells and signalling molecules to attempt to modulate the regenerative tissue. This review summarises the research that has been undertaken to date using this approach, with a particular emphasis on those techniques that have been introduced into clinical practice, via in vitro and preclinical studies.
Getgood
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A
Orthopaedic Research Unit, The University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. agetgood@btinternet.com
Brooks
R
R
Fortier
L
L
Rushton
N
N
D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D002358:Cartilage, Articular / Q000637:transplantation*; D019902:Chondrocytes / Q000637:transplantation; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use; D012106:Research; D013234:Stem Cells; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
D001672:Biocompatible Materials; D036341:Intercellular Signaling Peptides and Proteins