Green fluorescent proteins are light-induced electron donors.
Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment.
Bogdanov
Alexey M
AM
Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Mishin
Alexander S
AS
Yampolsky
Ilia V
IV
Belousov
Vsevolod V
VV
Chudakov
Dmitriy M
DM
Subach
Fedor V
FV
Verkhusha
Vladislav V
VV
Lukyanov
Sergey
S
Lukyanov
Konstantin A
KA
D016475:3T3 Cells; D000818:Animals; D004579:Electron Transport; D049452:Green Fluorescent Proteins / Q000096:biosynthesis / Q000737:chemistry* / Q000528:radiation effects; D006367:HeLa Cells; D006801:Humans; D008027:Light; D051379:Mice; D018613:Microscopy, Confocal; D008856:Microscopy, Fluorescence; D055668:Photochemical Processes
D049452:Green Fluorescent Proteins