Pulmonary edema in the transurethral resection syndrome induced with mannitol 5%.
Two patients developed the transurethral resection (TUR) syndrome after having absorbed mannitol 5% during TUR of the prostate. Both developed pulmonary edema and became severely hypoatremic (lowest serum sodium 99 and 97 mmol/l, respectively). Hypertonic saline was infused to raise the serum sodium level and plasma volume expansion used to combat hypotension. One patient also required positive-pressure ventilation and intravenous administration of norepinephrine. Both patients recovered completely.
Wang
J H
JH
Intensive Care Unit, Beijing Hospital, Beijing, China.
He
Q
Q
Liu
Y L
YL
Hahn
R G
RG
D004232:Diuretics / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced; D007038:Hypotonic Solutions / Q000627:therapeutic use; D008297:Male; D008353:Mannitol / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D009638:Norepinephrine / Q000627:therapeutic use; D019999:Pharmaceutical Solutions; D011175:Positive-Pressure Respiration; D011183:Postoperative Complications / Q000175:diagnosis*; D011470:Prostatic Hyperplasia / Q000601:surgery; D011654:Pulmonary Edema / Q000139:chemically induced*; D012964:Sodium / Q000097:blood; D013577:Syndrome; D020728:Transurethral Resection of Prostate; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D004232:Diuretics; D007038:Hypotonic Solutions; D019999:Pharmaceutical Solutions; D014662:Vasoconstrictor Agents; D008353:Mannitol; D012964:Sodium; D009638:Norepinephrine