[Solitary myofibroma of the mandible: a case report].
OBJECTIVE
Infantile myofibromatosis (IMF) are integrated in the group of fibromatosis juvenile-type which are benign mesenchymal lesions, characterized morphologically by a proliferation of fibroblasts and myofibroblastes, with perivascular pattern. Through a case of solitary myofibroma of the mandible, we will emphasize anatomo-clinical features and differential diagnosis.


METHODS
We report a case illustrating solitary myofibroma of the mandible in 18 month old infant.


RESULTS
The histological diagnosis was done on the identification of two separate components, a fascicular myofibroblastic pattern at the periphery with a hemangiopericytoma like pattern in the centre. Both components positive for alpha-smooth muscle actin and vimentin.


CONCLUSIONS
Solitary IMF is characterised by a single lesion arising from cutaneous, bony or soft tissues. Morphological and immunohistochemical examination allow the diagnosis of the typical form. The differential diagnosis includes other benign spindle cells tumours. The prognosis is excellent with possibility to regress spontaneously.
Ech-Charif
S
S
CHU, Hôpital des Spécialités, Service d'Anatomie pathologique, Rabat, Maroc. smy_charif@yahoo.fr
Benhammou
A
A
Maher
M
M
Séfiani
S
S
D006801:Humans; D007223:Infant; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis; D047708:Myofibroma / Q000175:diagnosis