title: Exercise, inflammation, and innate immunity.
abstract: Exercise has beneficial effects on chronic disease, and the drive to understand the mechanisms of these benefits is strong. This article presents several compelling potential mechanisms for the anti-inflammatory effect of exercise, including reduced percentage of body fat and macrophage accumulation in adipose tissue, muscle-released interleukin-6 inhibition of tumor necrosis factor-a, and the cholinergic anti-inflammatory pathway.
authors.affiliation: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 906 South Goodwin Avenue, Urbana, IL 6180, USA. woods1@uiuc.edu
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Woods
authors.forename: Victoria J
authors.initials: VJ
authors.lastname: Vieira
authors.forename: K Todd
authors.initials: KT
authors.lastname: Keylock
mesh_terms: D000818:Animals; D002908:Chronic Disease; D015444:Exercise / Q000502:physiology; D006801:Humans; D007113:Immunity, Innate; D007249:Inflammation