A patient with intractable posthypoxic myoclonus (Lance-Adams syndrome) treated with sodium oxybate.
Posthypoxic myoclonus is a rare and devastating complication of near-fatal cardiopulmonary arrest. Despite treatment with available anti-myoclonic agents, some patients may recover cognitively but remain completely disabled by severe myoclonus. We report a 16-year-old patient with severe treatment-refractory posthypoxic myoclonus, which improved markedly with administration of the drug sodium oxybate.
Arpesella
R
R
Department of Intensive Care and Emergency Unit, Ospedale Civile, Voghera, Italy.
Dallocchio
C
C
Arbasino
C
C
Imberti
R
R
Martinotti
R
R
Frucht
S J
SJ
D000293:Adolescent; D004569:Electroencephalography; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications*; D008297:Male; D009207:Myoclonus / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012978:Sodium Oxybate / Q000627:therapeutic use*; D013577:Syndrome
D012978:Sodium Oxybate