title: The nucleus inside out--through a rod darkly.
abstract: In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochromatin is found at the periphery and is interspersed in the nucleoplasm. Solovei et al. (2009) now reveal that this normal pattern is reversed in the retinal rod cells of mice. This inversion might serve to maximize light transmission to photoreceptors in nocturnal mammals.
authors.affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
authors.forename: Tobias
authors.initials: T
authors.lastname: Ragoczy
authors.forename: Mark
authors.initials: M
authors.lastname: Groudine
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000235:genetics*; D022041:Euchromatin / Q000737:chemistry; D006570:Heterochromatin / Q000737:chemistry; D051379:Mice; D017948:Retinal Rod Photoreceptor Cells / Q000166:cytology* / Q000502:physiology*; D014785:Vision, Ocular
chemical_list: D022041:Euchromatin; D006570:Heterochromatin