title: Voice-related quality of life after treatment of laryngeal cancer.
abstract: OBJECTIVE
  To determine patient-perceived voice-related quality of life in patients treated with various methods based on the results of Voice-Related Quality of Life (VRQOL) and Voice Handicap Index-10 (VHI-10) questionnaires.
  
  
  METHODS
  The VRQOL and VHI-10 questionnaires.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One hundred thirty-seven patients who had received definitive treatment of laryngeal cancer were followed-up at Hokkaido University Hospital, Sapporo, Japan, and were alive with no evidence of malignancy at the time of the survey.
  
  
  METHODS
  Patient-perceived voice-related quality of life based on the results of the VRQOL and VHI-10 questionnaires.
  
  
  RESULTS
  The mean VRQOL scores for patients who had undergone radiotherapy (n = 63), chemoradiotherapy (n = 29), laser surgery (n = 14), or total laryngectomy (n = 27) as final treatment of laryngeal cancer were 92.6, 92.9, 85.5, and 68.4, respectively; the mean VHI-10 scores were 2.87, 2.34, 5.43, and 11.26, respectively.
  
  
  CONCLUSIONS
  The VRQOL and VHI-10 questionnaires are important in judging the overall effectiveness of treatment options for laryngeal cancer.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan. noridate@med.hokudai.ac.jp
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Oridate
authors.forename: Akihiro
authors.initials: A
authors.lastname: Homma
authors.forename: Seigo
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakamaru
authors.forename: Fumiyuki
authors.initials: F
authors.lastname: Suzuki
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Hatakeyama
authors.forename: Shigenari
authors.initials: S
authors.lastname: Taki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sakashita
authors.forename: Noriko
authors.initials: N
authors.lastname: Nishizawa
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Furuta
authors.forename: Satoshi
authors.initials: S
authors.lastname: Fukuda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D007825:Laryngectomy; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D011795:Surveys and Questionnaires; D014832:Voice Disorders / Q000145:classification / Q000209:etiology* / Q000523:psychology