title: An in vitro study of the strain distribution in human femora with anatomical and customised femoral stems.
abstract: Hydroxyapatite-coated standard anatomical and customised femoral stems are designed to transmit load to the metaphyseal part of the proximal femur in order to avoid stress shielding and to reduce resorption of bone. In a randomised in vitro study, we compared the changes in the pattern of cortical strain after the insertion of hydroxyapatite-coated standard anatomical and customised stems in 12 pairs of human cadaver femora. A hip simulator reproduced the physiological loads on the proximal femur in single-leg stance and stair-climbing. The cortical strains were measured before and after the insertion of the stems. Significantly higher strain shielding was seen in Gruen zones 7, 6, 5, 3 and 2 after the insertion of the anatomical stem compared with the customised stem. For the anatomical stem, the hoop strains on the femur also indicated that the load was transferred to the cortical bone at the lower metaphyseal or upper diaphyseal part of the proximal femur. The customised stem induced a strain pattern more similar to that of the intact femur than the standard, anatomical stem.
authors.affiliation: Department of Orthopaedic Surgery, Trondheim University Hospital, Trondheim, Norway. Per-Olav.Ostbyhaug@stolav.no
authors.forename: P O
authors.initials: PO
authors.lastname: Østbyhaug
authors.forename: J
authors.initials: J
authors.lastname: Klaksvik
authors.forename: P
authors.initials: P
authors.lastname: Romundstad
authors.forename: A
authors.initials: A
authors.lastname: Aamodt
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials / Q000627:therapeutic use; D001696:Biomechanical Phenomena; D002102:Cadaver; D017886:Durapatite / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000502:physiology*; D006622:Hip Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design / Q000295:instrumentation*; D013314:Stress, Mechanical
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite