title: Review of adverse health effects of odours in field studies.
abstract: Exposure to environmental odours from industrial and agricultural premises, in addition to inducing annoyance responses in a dose-dependent manner, have been shown to be either directly associated with gastric symptoms as well as general health-related complaints under extreme exposure conditions, or indirectly mediated through odour annoyance under moderate odour exposure conditions.
  
  
  OBJECTIVE
  In order to examine the influence of hedonic tone (pleasantness-unpleasantness) and perceived odour strength (intensity) on symptom reporting the results of two pertinent field studies were analysed.
  
  
  METHODS
  In the vicinity of six industrial plants (sweets, rusk, textile, seed-oil, fat, cast iron) and eleven livestock operations (poultry, pig, cattle) assessment of odour exposure was done by means of systematic field inspections. Effect assessment was done by means of direct interviews (industrial: N=1456, agricultural: N=1053) using questionnaires covering odour annoyance, symptom reporting and relevant covariates.
  
  
  METHODS
  Multiple logistic regression analysis was used to establish dose-response associations between odour frequency, intensity and hedonic tone as independent variables and symptom reporting as dependent variable.
  
  
  RESULTS
  Exposure-symptom associations are strongly influenced by hedonic tone, whereas intensity has no additional predictive value. Adding odour annoyance to the regression model shows that symptom reporting is exclusively mediated by annoyance.
authors.affiliation: BGFA-Research Institute of Occupational Medicine, German Social Accident Insurance, Ruhr-University Bochum, Bürkle-de-la-Camp Platz 1, 44789 Bochum, Germany. k.sucker@gmx.de
authors.forename: K
authors.initials: K
authors.lastname: Sucker
authors.forename: R
authors.initials: R
authors.lastname: Both
authors.forename: G
authors.initials: G
authors.lastname: Winneke
mesh_terms: D000342:Affective Symptoms / Q000378:metabolism; D000393:Air Pollutants / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D005858:Germany; D006801:Humans; D009812:Odorants / Q000032:analysis*; D012044:Regression Analysis
chemical_list: D000393:Air Pollutants