[Cytology and immunophenotyping of acute promyelocytary leukaemia].
Acute promyelocytic leukaemia (AML3) is characterized by particular clinical and biological features. We report the cytology and the immunophenotype of 14 AML3 from which 3 were AML3v. A double negativity of HLA-DR and CD34 is found in 12 cases and aberrant expression of CD2 in 2AML3v. Aberrant expression of CD56 and CD22 was shown in, respectively, one case, CD15, CD65 and CD117 expressions were variable. Cytological diagnosis is often evident, although in some cases, it is not typical and immunophenotype will contribute to the diagnosis.
Gouider
E
E
Service d'Hématologie Biologique- Hôpital Aziza Othmana, Tunis. ebelhadjali@yahoo.fr
Ben Salah
N
N
Jeddi
R
R
Belakhal
F
F
Meddeb
B
B
Hafsia
R
R
D015703:Antigens, CD / Q000097:blood; D018952:Antigens, CD34 / Q000097:blood; D015214:Antigens, Differentiation, Myelomonocytic / Q000097:blood; D001856:Bone Marrow Examination; D018801:CD2 Antigens / Q000097:blood; D019002:CD56 Antigen / Q000097:blood; D003584:Cytological Techniques / Q000379:methods*; D005434:Flow Cytometry / Q000379:methods; D006684:HLA-DR Antigens / Q000097:blood; D006801:Humans; D016130:Immunophenotyping / Q000379:methods*; D007621:Karyotyping / Q000379:methods; D015473:Leukemia, Promyelocytic, Acute / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D016256:Lewis X Antigen / Q000097:blood; D019009:Proto-Oncogene Proteins c-kit / Q000097:blood; D051918:Sialic Acid Binding Ig-like Lectin 2 / Q000097:blood; D014416:Tunisia
D015703:Antigens, CD; D018952:Antigens, CD34; D015214:Antigens, Differentiation, Myelomonocytic; D018801:CD2 Antigens; D019002:CD56 Antigen; C477320:CD65s antigen, human; D006684:HLA-DR Antigens; D016256:Lewis X Antigen; D051918:Sialic Acid Binding Ig-like Lectin 2; D019009:Proto-Oncogene Proteins c-kit