Schizotypal personality traits and atypical lateralization in motor and language functions.
Atypical cerebral lateralization in motor and language functions in regard to schizotypal personality traits in healthy populations, as well as among schizophrenic patients, has attracted attention because these traits may represent a risk factor for schizophrenia. Although the relationship between handedness and schizotypal personality has been widely examined, few studies have adopted an experimental approach. This study consisted of three experiments focusing on motor and language functional lateralization in regard to schizotypal personality in the absence of mental illness: line-drawing, finger tapping, and a semantic go/no-go task. The results suggested that positive schizotypal personality might be related to functional non-lateralization in regard to at least some functions (e.g., spatial motor control and semantic processing in the present study). Subjects with high schizotypal personality traits performed equally with their right and left-hands in the line-drawing task and they reacted equally with their right and left-hands in a semantic go/no-go task involving semantic auditory stimuli presented in both ears. However, those low in schizotypal personality traits showed typical lateralization in response to these tasks. We discuss the implications of these findings for schizotypal atypical lateralization.
Asai
Tomohisa
T
Department of Cognitive and Behavioral Science, Graduate School of Arts and Sciences, University of Tokyo, Meguro-ku, Tokyo, Japan. as@beck.c.u-tokyo.ac.jp
Sugimori
Eriko
E
Tanno
Yoshihiko
Y
D000161:Acoustic Stimulation; D000293:Adolescent; D000704:Analysis of Variance; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007802:Language; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D010551:Personality / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time; D012569:Schizotypal Personality Disorder / Q000503:physiopathology* / Q000523:psychology*; D012660:Semantics; D013067:Speech Perception / Q000502:physiology; D011795:Surveys and Questionnaires; D013647:Task Performance and Analysis; D055815:Young Adult