[A patient with multiple skin metastases from breast cancer responding to S-1 effectively under treatment with trastuzumab].
We report a case of a 52-year-old female with multiple skin metastases from breast cancer who responded to S-1. She underwent surgery of her right breast in March 2000 and the left in June 2006. Multiple skin metastases were later detected. As there was no hormone sensitivity, chemotherapy was selected. We started treatment with administration of S-1 at 120mg/day(4 weeks)and trastuzumab. Thoracic CT at the end of the three courses revealed the disappearance of the multiple skin metastases. No major side effects were seen. It was concluded from these findings that S-1 could be safely and effectively administered to advanced breast cancer patients.
Tokugawa
Tomoki
T
Department of Breast Center, Nara City Hospital.
Kobayashi
Aya
A
Okubo
Keiko
K
Matsuyama
Tomohiko
T
Imai
Shunsuke
S
Koyama
Hiroshi
H
D000911:Antibodies, Monoclonal / Q000276:immunology / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D018450:Disease Progression; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007167:Immunotherapy; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D000068878:Trastuzumab
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D014408:Biomarkers, Tumor; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000068878:Trastuzumab