title: Roger T. Sherman Lecture. Advances in the management of blunt thoracic aortic injury: Parmley to the present.
abstract: This article traces the evolution in management of blunt aortic injury (BAI) over the past 50 years from the time of the seminal description from Parmley in 1958. There have been major advances in both diagnostics and treatment paradigms with very rapid technologic advances occurring over the past decade. For many years, conventional aortography was the principle diagnostic tool, but it has been replaced by the progression of CT. The widespread adoption of antihypertensive therapy has sharply reduced the incidence of aortic rupture before planned reconstruction. Many patients with major associated injuries have definitive treatment of BAI managed in a delayed fashion with the use of hypertensives, which appears to improve outcomes. In the past 5 years, definitive treatment has changed with the majority of injuries being treated today with endoluminal stent grafts as opposed to open thoracotomy and traditional repair techniques. Paraplegia rates have diminished from 8 to 10 per cent down to 1 to 2 per cent in association with these therapeutic advances.
authors.affiliation: Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA. tfabian@utmem.edu
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Fabian
mesh_terms: D001013:Aorta, Thoracic / Q000293:injuries*; D001018:Aortic Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D001027:Aortography / Q000379:methods*; D003937:Diagnosis, Differential; D006801:Humans; D012421:Rupture; D013898:Thoracic Injuries / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013908:Thoracotomy / Q000379:methods; D014057:Tomography, X-Ray Computed; D014656:Vascular Surgical Procedures / Q000379:methods*; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000175:diagnosis / Q000601:surgery