title: Bioactive and metal uptake studies of carboxymethyl chitosan-graft-D-glucuronic acid membranes for tissue engineering and environmental applications.
abstract: Carboxymethyl chitosan-graft-D-glucuronic acid (CMCS-g-D-GA) was prepared by grafting D-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and then the membranes were made from it. In this work, the bioactivity studies of CMCS-g-D-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-D-GA membranes were found to be bioactive. The adsorption of Ni2+, Zn2+ and Cu2+ ions onto CMCS-g-D-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-D-GA for Ni2+, Zn2+ and Cu2+ was found to be 57, 56.4 and 70.2 mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications.
authors.affiliation: Faculty of Chemistry, Materials and Bioengineering and High Technology Research Centre, Kansai University, Osaka 564-8680, Japan. jayakumar77@yahoo.com
authors.forename: R
authors.initials: R
authors.lastname: Jayakumar
authors.forename: M
authors.initials: M
authors.lastname: Rajkumar
authors.forename: H
authors.initials: H
authors.lastname: Freitas
authors.forename: P T
authors.initials: PT
authors.lastname: Sudheesh Kumar
authors.forename: S V
authors.initials: SV
authors.lastname: Nair
authors.forename: T
authors.initials: T
authors.lastname: Furuike
authors.forename: H
authors.initials: H
authors.lastname: Tamura
mesh_terms: D000327:Adsorption; D048271:Chitosan / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D004777:Environment; D020723:Glucuronic Acid / Q000737:chemistry* / Q000378:metabolism; D007700:Kinetics; D008567:Membranes, Artificial; D008670:Metals / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D017550:Spectroscopy, Fourier Transform Infrared; D023822:Tissue Engineering / Q000379:methods*; D018508:Water Purification; D014961:X-Ray Diffraction
chemical_list: D008567:Membranes, Artificial; D008670:Metals; C504164:O-carboxymethylchitosan; D020723:Glucuronic Acid; D048271:Chitosan