title: [Relationship between preeclampsia umbilical blood flow and perinatal outcomes].
abstract: OBJECTIVE
  To study the relationship between preeclampsia umbilical blood flow changes and the pregnancy outcomes.
  
  
  METHODS
  The umbilical arterial blood flow parameters including the S/D, pulsatility index (PI), resistance index (RI) and the average birth weight, Apgar score and placental weight changes were analyzed in 106 preeclampsia patients (including 43 mild and 63 severe cases), with 89 women with normal pregnancy as the control. The relation between the blood flow parameters and the perinatal outcomes were analyzed.
  
  
  RESULTS
  S/D, PI, and RI all tended to increase with the severity of preeclampsia, and these indices were significantly higher in patients with severe preeclampsia than in the control group (P<0.01) but showed no significant differences between mild preeclampsia group and the control group (P>0.05). The average birth weight of the newborns, Apgar scores, and placental weight were significantly lower (P<0.01), and the incidence of fetal growth restriction (FGR) and perinatal mortality significantly higher in severe preeclampsia group than in the control group (P<0.01). No significant differences were found in these parameters between the mild preeclampsia and the control groups (P>0.05).
  
  
  CONCLUSIONS
  Umbilical artery blood flow parameters as indicators for determining the fetal status can be used to predict the pregnancy outcomes.
authors.affiliation: Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. chen781218@yahoo.com.cn
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Yan-hong
authors.initials: YH
authors.lastname: Yu
authors.forename: Zhi-jian
authors.initials: ZJ
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Qin
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D054238:Perinatal Mortality; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D014470:Umbilical Cord / Q000098:blood supply*; D055815:Young Adult