Total synthesis of (+)-conagenin.
A new approach for the synthesis of the (+)-conagenin has been achieved based on Evans asymmetry syn-aldol reaction and the self-regeneration of stereocenters strategy.
Jiao
Xiao-Zhen
XZ
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Wang
Li-Ping
LP
Xiao
Qiong
Q
Xie
Ping
P
Liang
Xiao-Tian
XT
D000447:Aldehydes / Q000737:chemistry; D015394:Molecular Structure; D012694:Serine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry
D000447:Aldehydes; C069645:conagenin; D012694:Serine; C116609:3-hydroxybutanal