title: Racial/ethnic disparity in kidney transplantation outcomes: influence of donor and recipient characteristics.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the basis for the racial/ethnic disparity in kidney allograft survival.
  
  
  METHODS
  We conducted a retrospective study of 2130 patients who underwent kidney transplantation between January 1995 and December 2003. Patient and graft survivals were compared using Kaplan-Meier analysis.
  
  
  RESULTS
  Black recipients were more likely than white recipients to have hepatitis C infection (24.6% vs 7.1%), current tobacco use (21.2% vs 13.1%), previous alcohol use (22.6% vs 9.7%), and past illicit drug use (13.6% vs 3.9%). Current employment was less common among blacks. Additionally, black recipients were more likely to have a prior kidney transplant (16.7% vs 11.0%) and to have a cadaver kidney donor (74% vs 56.5%). The 5-year allograft survival rate was 72% for whites and 59% for blacks (p < .01). Previous kidney transplantation, cadaveric donor, donor age, recipient employment status, and recipient tobacco use were associated with allograft survival in a Cox proportional hazard model.
  
  
  CONCLUSIONS
  Graft survival rate in black kidney transplant recipients is significantly lower than whites, and this disparity can be partially explained by the low rate of live donors and a higher previous transplantation rate in blacks.
authors.affiliation: University of Maryland School of Medicine, Department of Medicine Baltimore, Maryland, USA.
authors.forename: Eyob
authors.initials: E
authors.lastname: Feyssa
authors.forename: Charlotte
authors.initials: C
authors.lastname: Jones-Burton
authors.forename: Gary
authors.initials: G
authors.lastname: Ellison
authors.forename: Benjamin
authors.initials: B
authors.lastname: Philosophe
authors.forename: Charles
authors.initials: C
authors.lastname: Howell
mesh_terms: D000328:Adult; D001741:Black or African American; D002102:Cadaver; D015331:Cohort Studies; D005260:Female; D006085:Graft Survival; D054625:Healthcare Disparities / Q000706:statistics & numerical data*; D006801:Humans; D053208:Kaplan-Meier Estimate; D016030:Kidney Transplantation / Q000208:ethnology* / Q000276:immunology*; D008297:Male; D008396:Maryland; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors; D016896:Treatment Outcome; D044465:White People