[Sigmoid colon cancer in a woman developing 22 years after radiation therapy for a yolk sac tumor].
A 34-year-old woman was referred to our hospital with ileus. She had undergone surgical resection following chemotherapy for yolk sac tumor at the age of 12 years, and had received additional surgery and radiation therapy for a local recurrence at age 13. Following evaluation, a sigmoid colon tumor was detected and was surgically resected. Histology proved well differentiated adenocarcinoma with chronic irradiation colitis, suggesting that irradiation may have induced the colon cancer.
Ui
Takashi
T
Department of Surgery, Jichi Medical University.
Horie
Hisanaga
H
Sato
Hirotake
H
Miyakura
Yasuyuki
Y
Sakuma
Yasunaru
Y
Hyodo
Masanobu
M
Togashi
Kazutomo
K
Yasuda
Yoshikazu
Y
Nagai
Hideo
H
Matsubara
Daisuke
D
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D017024:Chemotherapy, Adjuvant; D002908:Chronic Disease; D003092:Colitis / Q000209:etiology; D018240:Endodermal Sinus Tumor / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000532:radiotherapy*; D010052:Ovariectomy; D011878:Radiotherapy / Q000009:adverse effects*; D012811:Sigmoid Neoplasms / Q000209:etiology* / Q000473:pathology; D013997:Time Factors