Subacute cutaneous lupus erythematosus after immunotherapy for renal-cell carcinoma: the case for interferon-alpha.
Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized by papulosquamous or annular lesions. It can be caused by a variety of medications. We report a case of SCLE in a patient after interferon-alpha treatment for metastatic renal-cell carcinoma and discuss the potential role of interferons in the pathogenesis of CLE.
Lee
H Y
HY
Dermatology Unit, Singapore General Hospital, Singapore. lee.haur.yueh@singhealth.com.sg
Pang
S M
SM
D044466:Asian People; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects*; D016898:Interferon-alpha / Q000009:adverse effects*; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged
D007155:Immunologic Factors; D016898:Interferon-alpha