Life-threatening infection caused by daptomycin-resistant Corynebacterium jeikeium in a neutropenic patient.
Daptomycin is a novel lipopeptide antibiotic agent approved for the treatment of gram-positive life-threatening infections. Here we report, for the first time, the isolation of a highly daptomycin-resistant strain of Corynebacterium jeikeium causing a life-threatening infection in a neutropenic patient undergoing cord blood transplantation for secondary acute myeloid leukemia.
Schoen
Christoph
C
Institute for Hygiene and Microbiology, Julius Maximilian University, Würzburg, Germany.
Unzicker
Christian
C
Stuhler
Gernot
G
Elias
Johannes
J
Einsele
Hermann
H
Grigoleit
Götz Ulrich
GU
Abele-Horn
Marianne
M
Mielke
Stephan
S
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects; D003352:Corynebacterium / Q000187:drug effects* / Q000302:isolation & purification*; D003354:Corynebacterium Infections / Q000382:microbiology*; D017576:Daptomycin / Q000494:pharmacology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D017576:Daptomycin