Using azobenzene-embedded self-assembled monolayers to photochemically control cell adhesion reversibly.
A celling point: A mixed self-assembled monolayer comprising two types of alkanethiols--one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion--enables cell adhesion to be modulated photochemically. The reversible conversion of the azobenzene moiety between E and Z configurations allows the surface to either support or resist cell adhesion.
Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, No.9 Section 4, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Dingbin
D
Liu
Yunyan
Y
Xie
Huawu
H
Shao
Xingyu
X
Jiang
D000595:Amino Acid Sequence; D000818:Animals; D001391:Azo Compounds / Q000737:chemistry*; D002448:Cell Adhesion; D002460:Cell Line; D007536:Isomerism; D008027:Light; D051379:Mice; D041681:NIH 3T3 Cells; D009842:Oligopeptides / Q000737:chemistry; D010777:Photochemistry
D001391:Azo Compounds; D009842:Oligopeptides; C047981:arginyl-glycyl-aspartic acid; C009850:azobenzene