Screening for novel regulators of embryonic stem cell identity.
Two recent studies, including one in this issue of Cell Stem Cell, have identified novel regulators of embryonic stem cell (ESC) self-renewal using genome-wide RNAi screens in mouse ESCs (Ding et al., 2009; Hu et al., 2009) and have further expanded the repertoire of factors that regulate ESC identity.
Subramanian
Vidya
V
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Klattenhoff
Carla A
CA
Boyer
Laurie A
LA
D000818:Animals; D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000378:metabolism; D020869:Gene Expression Profiling; D016678:Genome; D051379:Mice; D034741:RNA, Small Interfering / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism
D034741:RNA, Small Interfering; D014157:Transcription Factors