Intrinsic Birefringence of Multiple-Coiled DNA, Theory and Applications.
The intrinsic birefringence of multiple-coiled DNA is computed in terms of an equally dense array of parallel DNA molecules. The birefringence for n times-coiled DNA molecules is given by [Formula: see text] where beta(o) = 0, beta(i) = tan(-1) (p(i)/2pir(i)), p(i) = period of the i(th) helix coil and r(i) = radius of i(th) helix coil. The formula is applied to two cases of helically coiled DNA in biological material and found to agree quantitatively with experimental results.
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