Involvement of medial prefrontal cortex in emotion during feedback presentation.
It has been suggested that the posterior medial prefrontal cortex (pMPFC) implements cognitive functions involved during negative feedback processing. It has also been suggested that the presentation of the feedback elicits emotional processes. This functional MRI study examined whether pMPFC was associated with the emotional component in feedback processing. Participants were exposed to feedback while performing a version of a motion prediction task. The pMPFC was activated during negative feedback presentation and emotion-related activity was extracted from the pMPFC activation through parametric imaging analysis. It was found that the emotional pMPFC activity was greater in participants who scored higher on depressive mood scales. The results suggest that pMPFC also implements feedback-related emotional functions, which individually vary depending on depressive moods.
Jimura
Koji
K
Department of Physiology, The University of Tokyo School of Medicine, Tokyo, Japan. kjimura@wustl.edu
Konishi
Seiki
S
Asari
Tomoki
T
Miyashita
Yasushi
Y
D000328:Adult; D000339:Affect / Q000502:physiology; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology; D003866:Depressive Disorder / Q000523:psychology; D004193:Discrimination Learning / Q000502:physiology; D004644:Emotions / Q000502:physiology*; D030141:Feedback, Psychological / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D019964:Mood Disorders / Q000523:psychology; D009434:Neural Pathways / Q000502:physiology; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D017397:Prefrontal Cortex / Q000502:physiology*; D011340:Problem Solving / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012938:Social Perception; D013647:Task Performance and Analysis; D014705:Verbal Behavior / Q000502:physiology; D055815:Young Adult