Purpose in life is associated with mortality among community-dwelling older persons.
OBJECTIVE
To assess the association between purpose in life and all-cause mortality in community-dwelling elderly persons.


METHODS
We used data from 1238 older persons without dementia from two longitudinal cohort studies (Rush Memory and Aging Project and Minority Aging Research Study) with baseline evaluations of purpose in life and up to 5 years of follow-up to test the hypothesis that greater purpose in life is associated with a reduced risk of mortality among community-dwelling older persons.


RESULTS
The mean +/- standard deviation score on the purpose in life measure at baseline was 3.7 +/- 0.5 (range = 2-5), with higher scores indicating greater purpose in life. During the 5-year follow-up (mean = 2.7 years), 151 of 1238 persons (12.2%) died. In a proportional hazards model adjusted for age, sex, education, and race, a higher level of purpose in life was associated with a substantially reduced risk of mortality (hazard ratio = 0.60, 95% Confidence Interval = 0.42, 0.87). Thus, the hazard rate for a person with a high score on the purpose in life measure (score = 4.2, 90th percentile) was about 57% of the hazard rate of a person with a low score (score = 3.1, 10th percentile). The association of purpose in life with mortality did not differ among men and women or whites and blacks. Further, the finding persisted after the addition of terms for several potential confounders, including depressive symptoms, disability, neuroticism, the number of chronic medical conditions, and income.


CONCLUSIONS
Greater purpose in life is associated with a reduced risk of all-cause mortality among community-dwelling older persons.
Rush Alzheimer's Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA. Patricia_Boyle@rush.edu
Patricia A
PA
Boyle
Lisa L
LL
Barnes
Aron S
AS
Buchman
David A
DA
Bennett
D001741:Black or African American / Q000523:psychology / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000523:psychology*; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006040:Goals; D006801:Humans; D033182:Intention; D008137:Longitudinal Studies; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D012307:Risk Factors; D011795:Surveys and Questionnaires