Primary testicular presentation of ALK-1-negative anaplastic large cell lymphoma in a pediatric patient.
Anaplastic large cell lymphoma is a heterogeneous group of malignant non-Hodgkin lymphomas that occurs in up to 15% of all pediatric non-Hodgkin lymphomas. It is characterized by B-symptoms and involvement of extranodal sites such as skin, bone, and soft tissue. This brief report describes first reported case of pediatric primary testicular anaplastic large cell lymphoma in a 14-year-old boy. The presentation included acute testicular pain, fever, and vomiting. After chemotherapy and unilateral radical orchiectomy, patient continues in complete remission.
Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.
Joanne
J
Lagmay
Amanda
A
Termuhlen
Bonita
B
Fung
Mark
M
Ranalli
D030301:Activin Receptors, Type II / Q000378:metabolism*; D000293:Adolescent; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D002467:Cell Nucleus / Q000378:metabolism / Q000473:pathology; D006056:Golgi Apparatus / Q000378:metabolism / Q000473:pathology; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery; D008297:Male; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery; D013737:Testis / Q000473:pathology / Q000601:surgery
D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen; C425364:ACVRL1 protein, human; D030301:Activin Receptors, Type II