[Children and adolescents with obsessive-compulsive disorders].
OBJECTIVE
The aim of this prospective follow-up study is to describe the long-term outcome of obsessive-compulsive disorders (OCD) with onset in childhood or adolescence as well as psychiatric comorbidity.


METHODS
A cohort of 30 former patients who had been treated for OCD in the Clinic for Child and Adolescent Psychiatry of the University of Würzburg were assessed by means of standardized measures in a personal examination at the beginning of their treatment and again after a follow-up period of 6 years.


RESULTS
At follow-up, 46.7% of the participants still fulfilled the DSM-IV criteria for OCD. Some 23.3% of the former patients showed subclinical OCD symptoms. 70% met the criteria for any Axis I disorder. Predominantly anxiety and affective disorders, but also obsessive-compulsive and anxious-avoidant personality disorders were found. Six persons showed a complete remission.


CONCLUSIONS
The rate of 46.7% persistent OCD matches the outcomes found in a meta-analysis (41%); however, lower persistence rates were expected in view of improved treatment options. An extension of the sample planned. FActors maintaining preservation of OCD should be analyzed,
Zellmann
Henrike
H
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychotherapie und Psychosomatik der Universität Würzburg. zellmann@kjp.uni-wurzburg.de
Jans
Thomas
T
Irblich
Birgit
B
Hemminger
Uwe
U
Reinecker
Hans
H
Sauer
Cathrin
C
Lange
Klaus W
KW
Tucha
Oliver
O
Wewetzer
Christoph
C
Warnke
Andreas
A
Walitza
Susanne
S
D000293:Adolescent; D002648:Child; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D010552:Personality Assessment; D010554:Personality Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D011446:Prospective Studies; D016896:Treatment Outcome