[Asthma and obesity in childhood: what is the link?].
According to the definition (body mass index>97 degrees percentile), overweight and obesity concern 15% of French children. The parallel trends in the increase in asthma and obesity may indicate a potential link between these two conditions. The purpose of this study was to review the epidemiological data indicating a relationship between asthma and obesity, to evaluate the consequences of obesity on asthma and to assess the mechanisms of this association. We conclude with the implications for treatment strategies.
Deschildre
A
A
Unité de pneumologie pédiatrique, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille cedex, France. adeschildre@chru-lille.fr
Pin
I
I
Gueorguieva
I
I
de Blic
J
J
D054392:Adipokines / Q000502:physiology; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000403:Airway Resistance / Q000502:physiology; D018927:Anti-Asthmatic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology / Q000534:rehabilitation; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology; D006801:Humans; D020738:Leptin / Q000502:physiology; D008137:Longitudinal Studies; D008176:Lung Volume Measurements; D009765:Obesity / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology / Q000534:rehabilitation; D050177:Overweight / Q000453:epidemiology; D012130:Respiratory Hypersensitivity / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation; D012307:Risk Factors; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology
D054392:Adipokines; D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D020738:Leptin