Allergic hypersensitivity to topical and systemic corticosteroids: a review.
Corticosteroids, which are potent anti-inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross-reactions.
Department of Dermatology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, Brussels, Belgium.
M
M
Baeck
L
L
Marot
J-F
JF
Nicolas
C
C
Pilette
D
D
Tennstedt
A
A
Goossens
D000305:Adrenal Cortex Hormones / Q000737:chemistry / Q000276:immunology* / Q000627:therapeutic use; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000276:immunology* / Q000627:therapeutic use; D003429:Cross Reactions / Q000276:immunology; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D012867:Skin / Q000276:immunology / Q000473:pathology
D000305:Adrenal Cortex Hormones; D018926:Anti-Allergic Agents