Trends in antibacterial use in hospitalized pediatric patients in United States academic health centers.
Trends in pediatric antibacterial use were examined in 20 academic health centers during the period 2002-2007. There was a significant increase in the use of linezolid (P < .001) and of macrolides (P = .001) and a significant decrease in the use of aminoglycosides (P < .001) and of first-generation cephalosporins (P < .001).
School of Pharmacy, Department of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298-0533, USA. apakyz@vcu.edu
Amy L
AL
Pakyz
Holly E
HE
Gurgle
Omar M
OM
Ibrahim
Michael J
MJ
Oinonen
Ronald E
RE
Polk
D000046:Academic Medical Centers / Q000706:statistics & numerical data*; D000081:Acetamides / Q000627:therapeutic use; D000293:Adolescent; D000617:Aminoglycosides / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004363:Drug Utilization / Q000639:trends; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D000069349:Linezolid; D018942:Macrolides / Q000627:therapeutic use; D023303:Oxazolidinones / Q000627:therapeutic use; D010372:Pediatrics; D014481:United States
D000081:Acetamides; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D018942:Macrolides; D023303:Oxazolidinones; D000069349:Linezolid