Aging: shall we take the high road?
For ectotherms, lifespan is increased at low temperature and decreased at high temperature. A new study in Caenorhabditis elegans shows that thermosensory neurons can counteract the effects of high temperature on lifespan by controlling the activity of a steroid signaling pathway.
Mori
Ikue
I
Laboratory of Molecular Neurobiology, Department of Molecular Biology, Graduate School of Science, Nagoya University and CREST-JST, Nagoya, Japan. m46920a@nucc.cc.nagoya-u.ac.jp
Sasakura
Hiroyuki
H
D000375:Aging / Q000502:physiology*; D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D008136:Longevity / Q000502:physiology*; D008954:Models, Biological; D013696:Temperature; D013823:Thermoreceptors / Q000502:physiology*