Guanosine hydrogen-bonded scaffolds: a new way to control the bottom-up realisation of well-defined nanoarchitectures.
Over the last two decades, guanosine-related molecules have been of interest in different areas, ranging from structural biology to medicinal chemistry, supramolecular chemistry and nanotechnology. The guanine base is a multiple hydrogen-bonding unit, capable also of binding to cations, and fits very well with contemporary studies in supramolecular chemistry, self-assembly and non-covalent synthesis. This Concepts article, after reviewing on the diversification of self-organised assemblies from guanosine-based low-molecular-weight molecules, will mainly focus on the use of guanine moiety as a potential scaffold for designing functional materials of tailored physical properties.
Lena
Stefano
S
Dipartimento di Chimica Organica "A. Mangini", Alma Mater Studiorum - Università di Bologna, Via San Giacomo 11, 40126 Bologna (Italy), Fax: (+39) 051-209-5688.
Masiero
Stefano
S
Dipartimento di Chimica Organica "A. Mangini", Alma Mater Studiorum - Università di Bologna, Via San Giacomo 11, 40126 Bologna (Italy), Fax: (+39) 051-209-5688.
Pieraccini
Silvia
S
Dipartimento di Chimica Organica "A. Mangini", Alma Mater Studiorum - Università di Bologna, Via San Giacomo 11, 40126 Bologna (Italy), Fax: (+39) 051-209-5688.
Spada
Gian Piero
GP
Dipartimento di Chimica Organica "A. Mangini", Alma Mater Studiorum - Università di Bologna, Via San Giacomo 11, 40126 Bologna (Italy), Fax: (+39) 051-209-5688.
D006151:Guanosine / Q000031:analogs & derivatives* / Q000737:chemistry*; D006157:Guanosine Monophosphate / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D036103:Nanotechnology; D011108:Polymers / Q000737:chemistry
D011108:Polymers; D006151:Guanosine; D006157:Guanosine Monophosphate