[Unawareness of illness and neurocognition in schizophrenia].
OBJECTIVE
The aim of the study was to investigate the relationship between insight and cognitive function in patients diagnosed with schizophrenia. Insight into illness is a clinically important feature influencing clinical outcome and prognosis in schizophrenia. One ofthe most important and widely discussed in recent literature factors contributing to lack of insight is cognitive dysfunction, mainly that mediated by deficits in the frontal cortical systems. A number of studies, but not all, have observed correlations between unawareness in different insight dimensions and poor performance on working memory and executive function tests.


METHODS
102 individuals were included to the study, the SUMD scale (Scale for Assessment of Unawareness of Mental Disorder) was used to asses the insight, and the battery of the neuropsychological test was administrated to assess cognition.


RESULTS
The results indicate that only some of the insight dimensions were associated with neuropsychological assessment. The research confirmed some relationship between unawareness of effects of medications and memory functions and correlations between unawareness of social consequences of illness and executive functions. Relations between other insight dimensions and neurocognition was less clear, only unawareness of negative symptoms was related to the working memory test.


CONCLUSIONS
Lack of insight in schizophrenia was moderately associated with cognitive functions. Unawareness of the effects of medication was related to the working memory and learning process, unawareness of social consequences of the mental disorder was related to executive functions. Unawareness of negative symptoms showed stronger associations with cognition than unawareness of positive symptoms or disorganization.
Niedźwiedzka
Izabela
I
I Klinika Psychiatryczna IPiN w Warszawie.
Kühn-Dymecka
Aleksandra
A
Wciórka
Jacek
J
D000328:Adult; D001294:Attitude to Health; D001364:Awareness; D003674:Defense Mechanisms; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D010555:Personality Inventory; D011044:Poland; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012647:Self-Assessment; D012803:Sick Role; D012919:Social Behavior; D012938:Social Perception; D011795:Surveys and Questionnaires; D055815:Young Adult