[Hypotensive and metabolic effect of indapamide and perindopril in patients with type 2 diabetes and arterial hypertensia].
The aim of this work was to investigate influence of indapamide and perindopril on blood pressure and metabolism at patients with type 2 diabetes and new diagnosed arterial hypertension. It was shown that monotherapy with indapamide lowered systolic and diastolic arterial pressure and allowed to achieve full normalization of arterial pressure in 36,4+/-6,55% of cases. Monotherapy with perindopril also lowered systolic and diastolic arterial pressure and allowed to achieve full normalization of arterial pressure in 37,5+/-6,53% of cases (>0,05). Indapamide and perindopril had no negative effect on glycemia (HbA1c) and have shown a metabolic neutrality concerning lipids.
Askerov
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D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D007190:Indapamide / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D020913:Perindopril / Q000627:therapeutic use*; D016896:Treatment Outcome
D000959:Antihypertensive Agents; D007190:Indapamide; D020913:Perindopril