[Geroprotectors: specific action or hormesis?].
In recent years, a number of nutrients and chemicals including antioxidants, vitamins, and hormones are widely advertised as "anti-aging" drugs ("geroprotectors"). It is usually believed that life-extending capacity of geroprotectors may be attributed to their specific anti-aging mechanisms, even without solid scientific evidence. Induction of the hormetic adaptive response in stressed organisms could be alternative explanation. The evidence that life-extending effects of anti-aging drugs may be due to hormetic-like response is discussed in this analytic review.
Vaĭserman
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AM
D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000975:Antioxidants / Q000009:adverse effects / Q000494:pharmacology*; D005853:Geriatrics; D006728:Hormones / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans; D008136:Longevity / Q000187:drug effects / Q000502:physiology*; D014815:Vitamins / Q000009:adverse effects / Q000494:pharmacology*
D000975:Antioxidants; D006728:Hormones; D014815:Vitamins