Mesopic contrast sensitivity and ocular higher-order aberrations in eyes with conventional spherical intraocular lenses.
OBJECTIVE
To investigate relationship between mesopic contrast sensitivity (CS) function and ocular higher-order aberrations in eyes implanted with conventional spherical intraocular lenses (IOL).


METHODS
Prospective, nonrandomized case series.


METHODS
Sixty-eight eyes of 48 patients who attained best spectacle-corrected visual acuity (BSCVA) of 20/20 or better after phacoemulsification and spherical IOL implantation were included in the study. At 2 months postoperatively, mesopic CS was measured with the Mesotest II (Oculus; Wetsler, Germany), and ocular higher-order aberrations for a 4-mm pupil were measured with the Hartmann-Shack aberrometer. CS and letter CS under photopic conditions were recorded with the CSV-1000 charts (Vector Vision Co, Greenville, Ohio, USA).


RESULTS
There was significant correlation between mesopic CS and ocular fourth-order root mean square (RMS) of wavefront aberration (Spearman r(s) = -0.293; P = .017), but no correlation was found between mesopic CS and ocular third-order RMS (r(s) = 0.196; P = .189). Ocular third- and fourth-order RMS did not correlate with other parameters, including BSCVA, and CS and letter CS under photopic conditions.


CONCLUSIONS
Mesopic CS is significantly associated with ocular fourth-order RMS of wavefront aberrations in eyes implanted with conventional spherical IOLs.
Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.
Yuko
Y
Ishii
Chikako
C
Okamoto
Takahiro
T
Hiraoka
Fumiki
F
Okamoto
Tetsuro
T
Oshika
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015350:Contrast Sensitivity / Q000502:physiology*; D003623:Dark Adaptation / Q000502:physiology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology