Management of foetal hydrops secondary to Kell isoimmunisation via foetal blood transfusion: a Doppler-guided approach.
We describe a male neonate with foetal hydrops due to foetal anaemia caused by Kell isoimmunisation. The severity of anaemia was monitored by Doppler ultrasonography of the middle cerebral artery peak systolic velocity, and this was used to time the foetal blood transfusions. The 33-year-old Indian mother received a total of five foetal blood transfusions from 21 weeks to 31 weeks of gestation, resulting in resolution of the anaemia and hydrops.
Department of Maternal Foetal Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore. jasmine.mohd@singhealth.com.sg
J
J
Mohd
J
J
Tan
G S
GS
Yeo
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000628:therapy*; D001787:Blood Group Incompatibility / Q000097:blood / Q000628:therapy*; D002585:Cesarean Section; D004453:Echoencephalography; D017707:Erythrocyte Transfusion / Q000379:methods*; D005260:Female; D006400:Hematocrit; D006801:Humans; D015160:Hydrops Fetalis / Q000097:blood* / Q000628:therapy*; D007231:Infant, Newborn; D007626:Kell Blood-Group System; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014471:Umbilical Veins
D007626:Kell Blood-Group System