Sequence of a novel HLA-A2 allele in a haematopoietic stem cell donor of the international registry.
We report here the sequence of a new human leucocyte antigen-A2 allele, A*9251, identified in a volunteer haematopoietic stem cell donor of the international registry. A*9251 differs from A*02010101 by two nucleotides at codons 113-114, resulting in a single His>Asp substitution at codon 114.
Kervaire
B
B
National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, University Hospital, Geneva, Switzerland.
Schmidt
A H
AH
Villard
J
J
Tiercy
J-M
JM
D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001216:Asparagine / Q000378:metabolism; D001483:Base Sequence; D003062:Codon; D017931:DNA Primers / Q000737:chemistry / Q000235:genetics; D005091:Exons; D015789:HLA-A2 Antigen / Q000235:genetics*; D006412:Hematopoietic Stem Cells; D006801:Humans; D008863:Microspheres; D008969:Molecular Sequence Data; D020411:Oligonucleotide Array Sequence Analysis; D012042:Registries; D017422:Sequence Analysis, DNA; D009626:Terminology as Topic; D014019:Tissue Donors
D003062:Codon; D017931:DNA Primers; D015789:HLA-A2 Antigen; D001216:Asparagine