[Systematic review on safety and efficacy of lateral node dissection in rectal cancer].
OBJECTIVE
To evaluate the safety and efficacy of lateral node dissection in rectal cancer.


METHODS
Data of safety and efficacy in 27 case-controlled studies comparing lateral node dissection and non-lateral node dissection in rectal cancer were meta-analyzed using fixed effect model or random effect model.


RESULTS
The increased operating time, blood loss and urinary dysfunction were more common in lateral node dissection group. The postoperative total complications, pelvic abscess, anastomotic leak, sexual dysfunction and defecation dysfunction were similar in both groups. There was no reasonably clear evidence in favor of lateral node dissection for recurrence, local recurrence, distal metastasis and 5-year survival.


CONCLUSIONS
Lateral node dissection can neither reduce recurrence nor improve survival in the current study, which is not recommended to be a routine procedure in rectal cancer surgery.
Department of Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Xiao-Jian
XJ
Wu
Mei-Jin
MJ
Huang
Xiao-Sheng
XS
He
Xu-Yu
XY
Zhou
Yi-Feng
YF
Zou
Jian-Ping
JP
Wang
Ping
P
Lan
D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects; D012004:Rectal Neoplasms / Q000601:surgery*; D016896:Treatment Outcome