Paratesticular paraganglioma: a rare cause of an intrascrotal mass.
We describe a case of a paratesticular paraganglioma in a 33-year-old man who presented with a scrotal mass and underwent a right testicular exploration. Metastasis is the only definite criterion for diagnosis of a malignant paraganglioma; however, lymphovascular invasion was noted in this case, which warranted a close clinical surveillance. The patient is currently well with no evidence of disease 18 months after radical orchiectomy. Paratesticular paragangliomas are extremely rare tumors with 6 cases reported in English literature. The histogenesis of these tumors is unknown. Though the histology and immunohistochemistry resemble those of paragangliomas at any other location, these tumors raise a plethora of differential diagnoses especially with the more commonly occurring tumors. Herein the relevant histopathologic differential diagnoses are discussed along with a brief review of literature.
Gupta
Ruta
R
Department of Pathology Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
Howell
R Spencer
RS
Amin
Mahul B
MB
D018254:Adenomatoid Tumor / Q000175:diagnosis; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis; D017600:Neuroectodermal Tumor, Melanotic / Q000175:diagnosis; D010236:Paraganglioma, Extra-Adrenal / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
D014408:Biomarkers, Tumor