Minor chemical constituents of Caesalpinia bonduc.
From the ethanolic extract of Caesalpinia bonduc, one new diterpene, neocaesalpin P (1) and six known diterpenoids, neocaesalpin H (2), cordylane A (3), caesalpinin B (4), bonducellpin E (5), caesalpinolide A (6), and 17-methylvouacapane-8(14),-9(11)-diene (7) were isolated. Structures of these compounds were determined from NMR spectroscopic studies. Compounds 1-7 exhibited modest antibacterial activities. All of these compounds were weakly active in glutathione S-transferase inhibition assays.
Ata
Athar
A
Department of Chemistry, The University of Winnipeg, 515 Portage Ave. Winnipeg, MB, R3B 2E9 Canada. a.ata@uwinnipeg.ca
Udenigwe
Chibuike C
CC
Gale
Elikana M
EM
Samarasekera
Radhika
R
D029911:Caesalpinia / Q000737:chemistry*; D004224:Diterpenes / Q000032:analysis* / Q000302:isolation & purification* / Q000378:metabolism; D000431:Ethanol; D005982:Glutathione Transferase / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D004224:Diterpenes; D000431:Ethanol; D005982:Glutathione Transferase