Plasmonically controlled nucleic acid dehybridization with gold nanoprisms.
Remote release: Triangular gold nanoprisms convert 1064 nm laser irradiation into heat selectively to allow the dehybridization of oligonucleotide conjugated to their surface (see scheme). These conjugates show unprecedented morphological stability under hours of irradiation. Released nucleic acids are unharmed by this process and can be repeatedly dehybridized and sequestered under spatiotemporal control.
Jones
Matthew R
MR
Department of Chemistry, International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
Millstone
Jill E
JE
Giljohann
David A
DA
Seferos
Dwight S
DS
Young
Kaylie L
KL
Mirkin
Chad A
CA
D006046:Gold / Q000737:chemistry*; D007834:Lasers; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry*; D020349:Surface Plasmon Resonance
D009841:Oligonucleotides; D006046:Gold