[Comparison of the frequencies and distributions of unexpected antibodies based on different calculation criteria].
BACKGROUND
The frequencies and distributions of unexpected antibodies have been reported using two different criteria, based on either number of persons tested or number of tests performed. But there has been no study that compared the results of analyses based on these two different criteria using the same data set.


METHODS
Unexpected antibody tests performed in a University Hospital during recent 6 yr (January 2002-December 2007) were retrospectively analyzed: 76,985 tests (59,503 persons) for screening and 875 tests (749 persons) for identification. Data were analyzed using two different criteria, based on 'persons tested' and 'tests performed'. Antibodies had been screened and identified using LISS/Coombs gel cards with DiaMed-ID system (DiaMed AG, Switzerland).


RESULTS
Frequencies of unexpected antibodies based on 'persons tested' and 'tests performed' were 1.32% and 1.34%, respectively (P=0.88). For frequently detected as well as rarely detected antibodies, there were no significant differences in the frequencies based on two different criteria. However, for rarely detected antibodies (anti-Xg(a) and Anti-E & D), the frequencies based on 'tests performed' were higher than those based on 'persons tested', affecting a change in the order of frequencies of antibodies detected.


CONCLUSIONS
As there were no significant differences in the frequencies of unexpected antibodies calculated using two different criteria, both criteria can be used together for the patient population in our hospital. However, two criteria should be compared to validate the results for other populations.
Department of Laboratory Medicine, School of Medicine, Pusan National University, Seo-gu, Busan, Korea.
Shine Young
SY
Kim
Jeong Eun
JE
Kang
Du Yeal
du Y
Song
Kyung Hwan
KH
Kim
Hyung Hoi
HH
Kim
Eun Yup
EY
Lee
Han Chul
HC
Son
D001789:Blood Group Antigens / Q000276:immunology*; D003627:Data Interpretation, Statistical; D006801:Humans; D007518:Isoantibodies / Q000097:blood / Q000276:immunology*; D012189:Retrospective Studies
D001789:Blood Group Antigens; D007518:Isoantibodies