Equine herpesvirus-1, non-neurogenic pathotype, in a 9-year-old American Saddlebred with neurological signs.
Equine herpesvirus 1 (EHV-1) causes rhinopneumonitis, abortion, and rarely, myeloencephalopathy. The neurovirulence of this virus is due to a point mutation in the DNA polymerase gene. Diagnosis by virus isolation has been replaced by real-time polymerase chain reaction (RT-PCR) assays that can detect strains, viral loads, and states; this may aid in control and management of the disease.
Heerkens
Tammy M-J
TM
Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. theerken@uoguelph.ca
D000818:Animals; D017809:Fatal Outcome; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004861:Herpesvirus 1, Equid / Q000302:isolation & purification*; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D009460:Neurologic Examination / Q000662:veterinary; D016133:Polymerase Chain Reaction / Q000662:veterinary