Electron transfer in peptides with cysteine and methionine as relay amino acids.
Caught on the hop: In multistep electron transfer (ET) reactions through peptides, aliphatic amino acids can also act as relay stations. With cysteine, the reaction occurs as a proton-coupled electron transfer (PCET) with water used as a mediator for the proton transfer (see picture).
Wang
Min
M
Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland.
Gao
Jian
J
Müller
Pavel
P
Giese
Bernd
B
D003545:Cysteine / Q000737:chemistry*; D004579:Electron Transport; D008715:Methionine / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D014443:Tyrosine / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D010455:Peptides; D014867:Water; D014443:Tyrosine; D008715:Methionine; D003545:Cysteine