Aspergillus vertebral osteomyelitis and epidural abscess.
We present the first reported case of Aspergillus vertebral osteomyelitis and epidural abscess in Singapore in a 50-year-old man with post-tuberculous bronchiectasis. The patient presented with acute urinary retention and flaccid paraplegia. Despite surgical debridement and treatment with voriconazole, the patient developed multiorgan failure and died two weeks after presentation. Early diagnosis and prompt initiation of treatment are emphasised in the hope of improving the outcome of this aggressive condition.
Tew
C W
CW
Department of General Medicine, Alexandra Hospital, 378 Alexandra Road, Singapore. tewcheewee@hotmail.com
Han
F C
FC
Jureen
R
R
Tey
B H
BH
D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001232:Aspergillus fumigatus; D003937:Diagnosis, Differential; D020802:Epidural Abscess / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D007262:Infusions, Intravenous; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D055732:Pulmonary Aspergillosis / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D011743:Pyrimidines / Q000008:administration & dosage; D013117:Spinal Cord Compression / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013166:Spondylitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013904:Thoracic Vertebrae / Q000473:pathology / Q000601:surgery; D014230:Triazoles / Q000008:administration & dosage; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole