Long-term follow-up on soft and hard tissue levels following guided bone regeneration treatment in combination with a xenogeneic filling material: a 5-year prospective clinical study.
OBJECTIVE
In the present prospective study, bone augmentation by guided bone regeneration (GBR) in combination with bovine hydroxyapatite (BHA) as filling material was evaluated with regard to soft and hard tissue stability over time.


METHODS
Implant survival, radiologic bone level (marginal bone level [MBL]), and clinical soft tissue parameters (marginal soft tissue level [MSTL]) were observed. Twenty patients received a total of 41 implants (Brånemark System, Nobel Biocare, Göteborg, Sweden) in conjunction with GBR treatment. The end point of the study was after 5 years following implant placement.


RESULTS
The cumulative implant survival rate was 97.5% corresponding to one implant failure. The radiologic evaluation of the MBL demonstrated a crestal bone height above the level of the fixture head. The bone height decreased from -3.51 to -2.38 mm (p < .001). The MSTL was -1.52 mm at baseline and -1.15 mm at the 5-year follow-up (p < .04) demonstrating a stable submucosal crown margin throughout the study period.


CONCLUSIONS
GBR treatment in combination with a xenogeneic filling material (BHA) is a viable treatment option in order to maintain stable hard and soft tissue levels in conjunction with augmentative procedure related to oral implant treatment.
Dahlin
C
C
Department of Oral & Maxillofacial Surgery, NÄL Medical Centre Hospital, Trollhättan, Sweden. dahlinchrister@hotmail.com
Simion
M
M
Hatano
N
N
D020341:Absorbable Implants; D000293:Adolescent; D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery*; D000539:Alveolar Process / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D001861:Bone Regeneration; D018786:Bone Substitutes; D003094:Collagen; D019232:Dental Restoration Failure; D017886:Durapatite; D005260:Female; D005500:Follow-Up Studies; D005881:Gingiva / Q000033:anatomy & histology; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011446:Prospective Studies; D011859:Radiography; D055815:Young Adult
C106416:Bio-Gide; D018786:Bone Substitutes; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D003094:Collagen; D017886:Durapatite