Oral bisphosphonate-related osteonecrosis of the jaws: favorable outcome after bisphosphonate holiday.
Bisphosphonate holiday has been suggested as a treatment modality for oral bisphosphonate-related osteonecrosis; however, there is debate that it can undermine beneficial effects of bisphosphonate therapy. A case successfully treated after bisphosphonate holiday is presented.
Kwon
Yong-Dae
YD
Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental School, Seoul, Korea. yongdae.kwon@gmail.com
Kim
Young-Ran
YR
Choi
Byung-Joon
BJ
Lee
Deok-Won
DW
Kim
Deog-Yoon
DY
D000284:Administration, Oral; D000368:Aged; D019386:Alendronate / Q000008:administration & dosage* / Q000009:adverse effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage* / Q000009:adverse effects; D024042:Collagen Type I / Q000097:blood; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008336:Mandibular Diseases / Q000097:blood / Q000139:chemically induced / Q000628:therapy*; D010020:Osteonecrosis / Q000097:blood / Q000139:chemically induced / Q000628:therapy*; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy; D010455:Peptides / Q000097:blood
D050071:Bone Density Conservation Agents; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D019386:Alendronate