Prebiotic effect of lacto-N-biose I on bifidobacterial growth.
We demonstrated the prebiotic effect of lacto-N-biose I (Galbeta1-3GlcNAc) on bifidobacteria in vitro. Lacto-N-biose I, a building unit of the type-I milk oligosaccharides, enhanced the growth of many bifidobacteria, especially Bifidobacterium bifidum, B. breve, and B. longum, which are predominant in the intestines of breast-fed infants. It might be a substantial, natural prebiotic in human colostrums.
Graduate School of Biostudies, Kyoto University, Kyoto, Japan. kiyohara@lif.kyoto-u.ac.jp
Masashi
M
Kiyohara
Asaki
A
Tachizawa
Mamoru
M
Nishimoto
Motomitsu
M
Kitaoka
Hisashi
H
Ashida
Kenji
K
Yamamoto
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D001644:Bifidobacterium / Q000187:drug effects* / Q000254:growth & development*; D003126:Colostrum / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007223:Infant; D011247:Pregnancy
C033398:galactosyl-1,3-N-acetylglucosamine; D000117:Acetylglucosamine