Interleukin-8 serum levels do not correlate with pelvic pain in patients with ovarian endometriomas.
OBJECTIVE
To determine whether interleukin-8 (IL-8) serum levels are correlated with pelvic pain in patients with ovarian endometriomas.


METHODS
Prospective study.


METHODS
Tertiary-care university hospital.


METHODS
Interleukin-8 serum levels were prospectively analyzed in 51 patients (group A, asymptomatic patients or patients with mild dysmenorrhea; group B, severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists between IL-8 serum levels and pelvic pain.


METHODS
Interleukin-8 serum levels determination.


METHODS
Interleukin-8 serum levels and pelvic pain.


RESULTS
From 56 patients, five cases were ultimately excluded because the histologic diagnosis was not cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean (+/-SD) IL-8 serum levels in group A were 6.41 +/- 12.17 pg/mL and in group B were 6.52 +/- 8.73 pg/mL.


CONCLUSIONS
Pain symptoms in ovarian endometriosis is not correlated with IL-8 serum levels.
Department of Obstetrics and Gynecology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain. mgmanero@unav.es
Manuel García
MG
Manero
Juan Luis
JL
Alcazar
D000328:Adult; D015415:Biomarkers / Q000097:blood*; D002908:Chronic Disease; D004412:Dysmenorrhea / Q000097:blood / Q000175:diagnosis; D004715:Endometriosis / Q000097:blood* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D016209:Interleukin-8 / Q000097:blood*; D010048:Ovarian Cysts / Q000097:blood / Q000175:diagnosis; D017699:Pelvic Pain / Q000097:blood* / Q000175:diagnosis*; D011446:Prospective Studies
D015415:Biomarkers; D016209:Interleukin-8