[First Danish case of Clostridium difficile ribotype 027].
Increasing rates of Clostridium difficile-associated diarrhoea (CDAD) with an unusual, severe course have been reported in Canada, USA and several European countries since 2003. A new virulent strain, PCR ribotype 027 (CD027), is associated with this increase. We report the first Danish case of CDAD caused by CD027. A 85-year-old woman was admitted to hospital with pneumonia. Following treatment initially with penicillin, secondly with moxifloxacin she developed bloody diarrhoea. A stool specimen showed CD027. She was treated with metronidazol for ten days and recovered completely.
Statens Serum Institut, Afdeling for Bakteriologi, Mykologi og Parasitologi, DK-2300 København S.
Lillian M
LM
Søes
Inger
I
Brock
Mia
M
Torpdahl
Søren
S
Persson
Karl M
KM
Christensen
Michael
M
Kemp
Katharina E P
KE
Olsen
D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000627:therapeutic use; D016360:Clostridioides difficile / Q000235:genetics / Q000472:pathogenicity*; D003428:Cross Infection / Q000382:microbiology* / Q000517:prevention & control / Q000635:transmission; D003967:Diarrhea / Q000188:drug therapy / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D004761:Enterocolitis, Pseudomembranous / Q000382:microbiology* / Q000517:prevention & control / Q000635:transmission; D005260:Female; D006801:Humans; D017053:Infection Control; D021521:Ribotyping; D014774:Virulence / Q000235:genetics
D000890:Anti-Infective Agents