[Sigmoid colon cancer in a woman developing 22 years after radiation therapy for a yolk sac tumor].
A 34-year-old woman was referred to our hospital with ileus. She had undergone surgical resection following chemotherapy for yolk sac tumor at the age of 12 years, and had received additional surgery and radiation therapy for a local recurrence at age 13. Following evaluation, a sigmoid colon tumor was detected and was surgically resected. Histology proved well differentiated adenocarcinoma with chronic irradiation colitis, suggesting that irradiation may have induced the colon cancer.
Department of Surgery, Jichi Medical University.
Takashi
T
Ui
Hisanaga
H
Horie
Hirotake
H
Sato
Yasuyuki
Y
Miyakura
Yasunaru
Y
Sakuma
Masanobu
M
Hyodo
Kazutomo
K
Togashi
Yoshikazu
Y
Yasuda
Hideo
H
Nagai
Daisuke
D
Matsubara
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D017024:Chemotherapy, Adjuvant; D002908:Chronic Disease; D003092:Colitis / Q000209:etiology; D018240:Endodermal Sinus Tumor / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000532:radiotherapy*; D010052:Ovariectomy; D011878:Radiotherapy / Q000009:adverse effects*; D012811:Sigmoid Neoplasms / Q000209:etiology* / Q000473:pathology; D013997:Time Factors