[The application of minisequencing reactions for haplogroup assignment of mitochondrial DNA].
In the last few years, one could observe an increased interest in mitochondrial DNA (mtDNA) single nucleotide polymorphisms (SNPs) as a result of their numerous applications in population genetics and forensic science. Continuous progress in molecular technologies together with an increasing body of phylogenetic knowledge, based mainly on complete mitochondrial genome sequencing, allows both for selection and accurate typing of many SNPs in mitochondrial DNA. Among the SNP typing techniques, due to its high sensitivity and promptness of determinations, minisequencing appears to be one of the fastest and most frequently applied methods in forensic laboratories. This review presents currently available minisequencing systems used for haplogroup assignment of mtDNA in European, East Asian and Native American populations.
Katedry Medycyny Sadowej UMK w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy.
Patrycja
P
Daca
Marta
M
Mielnik
Urszula
U
Rogalla
Katarzyna
K
Skonieczna
Katarzyna
K
Linkowska
Tomasz
T
Grzybowski
D044467:American Indian or Alaska Native / Q000235:genetics; D044466:Asian People / Q000235:genetics; D016172:DNA Fingerprinting; D004272:DNA, Mitochondrial / Q000235:genetics*; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA; D044465:White People / Q000235:genetics
D004272:DNA, Mitochondrial