Capacity of photodynamic therapy for microbial reduction in periodontal pockets.
Practitioners are not successful in implemented treatments due to the great difficulty in completely removing bacterial deposits and their endotoxins. This study aimed to evaluate the capacity of photodynamic therapy to reduce the numbers of viable bacteria in periodontal pockets. Microbiological samples were collected before and after scaling and after photodynamic therapy. Photodynamic therapy was performed through the insertion of the photosensitizer toluidine blue and Endo PTC into the pocket for 3 min, followed by photosensitization with low-intensity diode of 4 J/cm(2). The results (log(10)) were submitted to a descriptive analysis and a t-test. A reduction of 81.24% in the numbers of bacteria after scaling was observed, as well as 95.90% after photodynamic therapy (P < 0.01). Photodynamic therapy is indicated as an adjuvant treatment to reduce the numbers of viable bacteria in periodontal diseases.
Pinheiro
Sérgio Luiz
SL
Faculdade de Odontologia, Pontifícia Universidade Católica (PUC) Campinas, Bairro Panorama, Residencial Jardim das Palmeiras, Vinhedo, Campinas, São Paulo 13280-000, Brazil. psergio@usp.br
Donegá
Juliana Marla
JM
Seabra
Lia Maura Soares
LM
Adabo
Marina Dalto
MD
Lopes
Talita
T
do Carmo
Thiago Henrique Dias
TH
Ribeiro
Mariângela Cagnoni
MC
Bertolini
Patrícia Fernanda Roesler
PF
D000328:Adult; D015169:Colony Count, Microbial; D012534:Dental Scaling; D006801:Humans; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D028022:Low-Level Light Therapy / Q000379:methods*; D008875:Middle Aged; D010514:Periodontal Pocket / Q000188:drug therapy* / Q000382:microbiology* / Q000628:therapy; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage; D014048:Tolonium Chloride / Q000008:administration & dosage
D017319:Photosensitizing Agents; D014048:Tolonium Chloride