Effect of lingual and hypoglossal nerve reconstruction on swallowing function in head and neck surgery: prospective functional outcomes study.
OBJECTIVE
To examine the effect on oral swallowing function of reanastomosis of lingual and hypoglossal nerves divided and reconstructed during head and neck cancer surgery and to determine the importance (if any) of sensory reconstruction in oral cavity cancer surgery.


METHODS
Prospective cohort study.


METHODS
Forty-four patients underwent resection and free tissue reconstruction of oropharyngeal squamous cell carcinoma between January 1999 and September 2006. Postoperative lingual and hypoglossal nerve status was recorded. All patients were scheduled to undergo videofluoroscopic swallowing studies (VFSSs) pre- and 12 months postoperatively. The oral residue score, bolus oral transit time, and aspiration score were recorded for all patients completing the assessments.


RESULTS
The oral transit time and oral residue score increased in patients with both lingual and hypoglossal nerves resected. Oral swallowing efficiency was preserved if one or both of the lingual and hypoglossal nerves were preserved or reconstructed following cancer resection. Ninety-one percent of patients swallowed safely at 12 months postoperatively.


CONCLUSIONS
Loss of both the lingual (sensory) and hypoglossal (motor) supply of parts of the oral cavity has a detrimental effect on oral swallowing. If either the sensory or the motor supply to these regions can be preserved or reconstructed, oral swallowing efficiency can be maintained. During oral cancer extirpation, removal of muscular structures often negates possible motor reconstruction. This increases the need for sensate reconstruction of oral cavity defects via primary reanastomosis of nerves or sensate free tissue transfer to preserve oral swallowing efficiency.
O'Connell
Daniel A
DA
Division of Otolaryngology-Head and Neck Surgery, University of Alberta, Edmonton, Alberta.
Reiger
Jana
J
Dziegielewski
Peter T
PT
Tang
Judith Lam
JL
Wolfaardt
Johan
J
Harris
Jeffrey R
JR
Mlynarek
Alex
A
Seikaly
Hadi
H
D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D002277:Carcinoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D015331:Cohort Studies; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005471:Fluoroscopy; D005500:Follow-Up Studies; D006801:Humans; D007002:Hypoglossal Nerve / Q000601:surgery*; D008036:Lingual Nerve / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome; D014743:Videotape Recording