Multifaceted CFTR: novel role in ROS signaling and apoptotic cell death--a commentary on "CFTR mediates cadmium-induced apoptosis through modulation of ROS levels in mouse proximal tubule cells".
Thévenod
Frank
F
Department of Physiology and Pathophysiology, University of Witten/Herdecke, Witten, Germany. frank.thevenod@uni-wh.de
D000818:Animals; D017209:Apoptosis; D002104:Cadmium / Q000633:toxicity*; D002461:Cell Line, Transformed; D048429:Cell Size; D003550:Cystic Fibrosis / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics / Q000378:metabolism*; D048049:Extracellular Signal-Regulated MAP Kinases; D007687:Kidney Tubules, Proximal / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction
D017382:Reactive Oxygen Species; D002104:Cadmium; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D048049:Extracellular Signal-Regulated MAP Kinases