New antifungal therapies for the treatment of onychomycosis.
Onychomycosis is a common disorder of nails caused by diverse spectrum of fungi ranging from dermatophytes to nondermatophyte molds and yeasts. Presently, oral and topical therapies are the mainstay of treatment with oral therapies yielding somewhat better results. Though various treatment options are available to treat onychomycosis, search for a convenient, cost effective agent with high and long-lasting cure rates is continuing. Currently, many new therapies for onychomycosis are under investigation which includes new formulations of azoles, improvement of existing topical treatments through addition of ungual enhancers and new drugs with better nail permeation
Kumar
Sandeep
S
Massachusetts General Hospital, 50 Staniford Street 246, Boston, MA 02114, USA. harvardskinstudies@partners.org
Kimball
Alexa B
AB
D000284:Administration, Oral; D000287:Administration, Topical; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D015507:Drugs, Investigational / Q000008:administration & dosage / Q000627:therapeutic use*; D005533:Foot Dermatoses / Q000188:drug therapy* / Q000628:therapy*; D006229:Hand Dermatoses / Q000188:drug therapy* / Q000628:therapy*; D006801:Humans; D008872:Microwaves / Q000627:therapeutic use; D014009:Onychomycosis / Q000188:drug therapy* / Q000628:therapy*; D010778:Photochemotherapy / Q000379:methods; D014230:Triazoles / Q000627:therapeutic use
D000935:Antifungal Agents; D015507:Drugs, Investigational; D014230:Triazoles