Decreased Paneth cell defensin expression in ileal Crohn's disease is independent of inflammation, but linked to the NOD2 1007fs genotype.
C L
CL
Bevins
E F
EF
Stange
J
J
Wehkamp
D003424:Crohn Disease / Q000235:genetics* / Q000378:metabolism; D023082:Defensins / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D007077:Ileal Diseases / Q000235:genetics* / Q000378:metabolism; D007082:Ileum; D009154:Mutation; D053473:Nod2 Signaling Adaptor Protein / Q000235:genetics*; D019879:Paneth Cells / Q000378:metabolism*
D023082:Defensins; C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein