Silicone injection causing acute pneumonitis: a case series.
Local and systemic complications following injected silicone have been described, especially after cosmetic procedures by unlicensed practitioners. We report a retrospective case series of acute pneumonitis following silicone injection to the buttock. Medical records, pulmonary function tests, blood arterial gases, chest radiographs, and high-resolution computed tomography scans were reviewed. Five patients with acute pneumonitis after injected silicone were identified. All cases were men with a mean age was 25 years. Three patients had the procedure performed by the same practitioner. The amount of injected silicone ranged from 30 to 500 ml. The onset of clinical symptoms began as early as 24 h after injection to as late as 15 days. All cases had diffuse, peripheral, occasionally wedge-shaped opacities on high-resolution computed tomography. At presentation the mean oxygen saturation was 84%. All were treated with steroids and had clinical resolution of their illness within 1 month of presentation. Injection of silicone can lead to serious pulmonary complications but treatment with steroids seems to be beneficial.
Department of Pulmonary Fibrosis, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas (INER), Calzada de Tlalpan 4502, Col. Seccion XVI, Mexico City, Mexico. zamora72@gmail.com
Ana C
AC
Zamora
Harold R
HR
Collard
Lourdes
L
Barrera
Felipe
F
Mendoza
W Richard
WR
Webb
Guillermo
G
Carrillo
D000208:Acute Disease; D000328:Adult; D002081:Buttocks; D003357:Cosmetic Techniques / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D008007:Licensure, Medical; D008297:Male; D008800:Mexico; D011014:Pneumonia / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D012189:Retrospective Studies; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
D012828:Silicones; D013256:Steroids