Vinyl-, propargyl-, and allenylsilicon reagents in asymmetric synthesis: a relatively untapped resource of environmentally benign reagents.
An up-to-date in-depth review of the current virtues and limitations in the realm of carbonyl addition reactions with allenyl-, propargyl-, and vinylsilicon reagents, encompassing numerous practical as well as pedagogical principles is presented. Comparisons of chemo-, regio-, and stereoselectivity and reactivity are drawn. Synthetic applications and challenges associated with each class of organosilane are discussed threading together the prospects of these green carbanion surrogates.
Curtis-Long
Marcus J
MJ
Woodview, Nafferton, East Yorkshire, YO25 4JP, UK.
Aye
Yimon
Y
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D004777:Environment; D007202:Indicators and Reagents; D015394:Molecular Structure; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000480:Alkynes; D007202:Indicators and Reagents; D012821:Silanes; D014753:Vinyl Compounds