[Pancreatic cancer linked to life style and genome].
Since the prognosis of pancreatic cancer is poor in spite of surgical and drug therapy, the focus should be on the prevention and early detection of the disease. In Europe, smoking accounts for up to 30% of pancreatic cancers, and heavy drinking increases the risk of chronic pancreatitis and pancreatic cancer. Diabetes can be a risk factor for pancreatic cancer and constitute its initial symptom. Obesity and low physical activity are linked to the risk of pancreatic cancer. An increased risk of pancreatic cancer is also associated with a hereditary inflammation, cystic fibrosis, and with part of cystic tumors of the pancreas.
Sand
Juhani
J
TAYS, kirurgian, gastroenterologian ja syövänhoidon toimialue, Teiskontie 35, 33521 Tampere.
Räty
Sari
S
Nordback
Isto
I
D000428:Alcohol Drinking / Q000009:adverse effects; D048909:Diabetes Complications / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D008019:Life Style; D009765:Obesity / Q000150:complications; D010190:Pancreatic Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics; D011379:Prognosis; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects