[Asthma and obesity in childhood: what is the link?].
According to the definition (body mass index>97 degrees percentile), overweight and obesity concern 15% of French children. The parallel trends in the increase in asthma and obesity may indicate a potential link between these two conditions. The purpose of this study was to review the epidemiological data indicating a relationship between asthma and obesity, to evaluate the consequences of obesity on asthma and to assess the mechanisms of this association. We conclude with the implications for treatment strategies.
Unité de pneumologie pédiatrique, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille cedex, France. adeschildre@chru-lille.fr
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Deschildre
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Pin
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Gueorguieva
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de Blic
D054392:Adipokines / Q000502:physiology; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000403:Airway Resistance / Q000502:physiology; D018927:Anti-Asthmatic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology / Q000534:rehabilitation; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology; D006801:Humans; D020738:Leptin / Q000502:physiology; D008137:Longitudinal Studies; D008176:Lung Volume Measurements; D009765:Obesity / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology / Q000534:rehabilitation; D050177:Overweight / Q000453:epidemiology; D012130:Respiratory Hypersensitivity / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation; D012307:Risk Factors; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology
D054392:Adipokines; D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D020738:Leptin