A randomized, double-blind, placebo-controlled trial of relaxin for cervical ripening in post-delivery date pregnancies.
Recombinant human relaxin was used to attempt cervical ripening in post-delivery date pregnancies. High doses of relaxin were safe but did not advance cervical ripening or induce labor.
Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA.
Gerson
G
Weiss
Sam
S
Teichman
Dennis
D
Stewart
David
D
Nader
Susan
S
Wood
Elaine
E
Unemori
D020070:Cervical Ripening / Q000187:drug effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007276:Injections, Intraventricular; D011247:Pregnancy; D012065:Relaxin / Q000008:administration & dosage / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*
D012065:Relaxin