Rapid sequence induction in obstetrics revisited.
OBJECTIVE
The regimen of thiopental, succinylcholine (SCh) and unsupplemented nitrous oxide/oxygen for Caesarean section was first introduced 50 years ago. This review examines which elements have endured, what has changed, and how practice might alter in the very near future.


RESULTS
Sugammadex, a cyclodextrin, is capable of rapid reversal of profound rocuronium neuromuscular blockade.


CONCLUSIONS
It is now feasible that SCh might be replaced with a high-dose rocuronium-sugammadex combination.
Nottingham and East Midlands School of Anaesthesia, Nottingham, UK.
Lisa M
LM
Sharp
David M
DM
Levy
D000328:Adult; D000701:Analgesics, Opioid; D000773:Anesthesia, Obstetrical; D000777:Anesthetics; D002585:Cesarean Section; D005260:Female; D006801:Humans; D009467:Neuromuscular Depolarizing Agents; D011247:Pregnancy; D013390:Succinylcholine; D000077122:Sugammadex; D013874:Thiopental; D047408:gamma-Cyclodextrins
D000701:Analgesics, Opioid; D000777:Anesthetics; D009467:Neuromuscular Depolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D013390:Succinylcholine; D013874:Thiopental