A novel physiologic sampling pump capable of rapid response to breathing.
The merits of using physiologic sampling pumps (PSPs) instead of using constant-flow sampling pumps, i.e., "traditional sampling pumps" (TSPs), are discussed. A novel PSP that overcomes shortcomings of previous PSP designs is presented. Calibrated valves are used to obviate pump inertia that has limited the system response and accuracy of prior work. Technologies that provide minute ventilation (V[combining dot above](E)) of subjects in real time may therefore be used to the limit of their own accuracies to sample inhalation exposures. Analysis of the design and data from a prototype are presented to show how air sampling can be modulated to follow breathing.
Lee
Larry
L
National Institute for Occupational Safety and Health (NIOSH), Health Effects Laboratory Division (HELD), Morgantown, WV 26505-2888, USA.
Flemmer
Michael
M
Lee
Eun Gyung
EG
Harper
Martin
M
Lin
Ming-I
MI
Groves
William
W
Freivalds
Andris
A
Slaven
James
J
D000393:Air Pollutants / Q000032:analysis*; D004784:Environmental Monitoring / Q000295:instrumentation*; D006801:Humans; D016273:Occupational Exposure; D012119:Respiration
D000393:Air Pollutants