Unknown ankylosing spondylitis with only cardiac involvement in patient with surgical indication: Call for patient and family members immunological screening.
Aortic regurgitation (AR) and first-degree atrioventricular heart block (FDAVB) are encountered in ankylosing spondylitis (AS). This rheumatological disease also presents in 90% of the cases an immunogenetic marker that is Human Leucocyte Antigen-B27 (HLA-B27). In this report we describe a case of a patient presenting with AR, FDAVB, aneurysm and thinning of the ascending aortic wall, aneurysm of the sinuses of Valsalva and inferior myocardial infarction-like electrocardiographic pattern with unknown cardiac AS and absence of other AS-related systemic manifestations.
De Cicco
Giuseppe
G
Vizzardi
Enrico
E
Gelsomino
Sandro
S
Lorusso
Roberto
R
D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D017023:Coronary Angiography; D017548:Echocardiography, Transesophageal; D004562:Electrocardiography; D015796:HLA-B27 Antigen / Q000276:immunology*; D006322:Heart Aneurysm / Q000175:diagnosis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D006327:Heart Block / Q000175:diagnosis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D056989:Inferior Wall Myocardial Infarction / Q000175:diagnosis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000175:diagnosis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology
D015796:HLA-B27 Antigen