Implication of aberrant glycosylation in cancer and use of lectin for cancer biomarker discovery.
Aberrant glycosylation is frequently found in cancer, and efforts for biomarker discovery include the preparation of aberrant glycoproteins as promising analytes. Several lectins that bind to aberrant glycans and can be thus used to capture and enrich aberrant glycoproteins in the frontal stage during biomarker discovery are to be introduced.
Kim
Yong-Sam
YS
Daejeon-KRIBB-FHCRC Research Cooperation Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon, Korea.
Yoo
Hyang Sook
HS
Ko
Jeong Heon
JH
D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis* / Q000378:metabolism; D006031:Glycosylation; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism*
D014408:Biomarkers, Tumor; D037102:Lectins