Orthostatic hypertension: a measure of blood pressure variation for predicting cardiovascular risk.
Orthostatic hypertension, a measure of blood pressure (BP) variability, is a clinically important pathologic condition associated with the progression of target organ damage and subsequent cardiovascular risk. Orthostatic hypertension precedes hypertension and could be considered as prehypertension if a patient has seated clinic BP <140/90 mmHg. The simple examination of orthostatic BP changes using a self-measured home BP monitoring, through which abnormal pathological conditions can be detected with high reproducibility without the white-coat effect. Orthostatic hypertension is associated with morning hypertension and increased neurohumoral activation; however, the precise mechanism of orthostatic hypertension remains unclear, and accumulation of further clinical evidence is necessary.
Kario
Kazuomi
K
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan. kkario@jichi.ac.jp
D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000503:physiopathology; D004244:Dizziness / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D011237:Predictive Value of Tests; D012307:Risk Factors