Dynamic hybrid materials for constitutional self-instructed membranes.
Constitutional self-instructed membranes were developed and used for mimicking the adaptive structural functionality of natural ion-channel systems. These membranes are based on dynamic hybrid materials in which the functional self-organized macrocycles are reversibly connected with the inorganic silica through hydrophobic noncovalent interactions. Supramolecular columnar ion-channel architectures can be generated by reversible confinement within scaffolding hydrophobic silica mesopores. They can be structurally determined by using X-ray diffraction and morphologically tuned by alkali-salts templating. From the conceptual point of view, these membranes express a synergistic adaptive behavior: the simultaneous binding of the fittest cation and its anion would be a case of "homotropic allosteric interactions," because in time it increases the transport efficiency of the pore-contained superstructures by a selective evolving process toward the fittest ion channel. The hybrid membranes presented here represent dynamic constitutional systems evolving over time to form the fittest ion channels from a library of molecular and supramolecular components, or selecting the fittest ion pairs from a mixture of salts demonstrating flexible adaptation.
Cazacu
Adinela
A
Adaptive Supramolecular Nanosystems Group, Ecole Nationale Superieure de Chimie, Unité Mixte de Recherche 5635, Centre National de la Recherche Scientifique, Institut Européen des Membranes, University of Montpellier II, Montpellier, France.
Legrand
Yves-Marie
YM
Pasc
Andreea
A
Nasr
Gihane
G
Van der Lee
Arie
A
Mahon
Eugene
E
Barboiu
Mihail
M
D040761:Biomimetic Materials / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D007473:Ion Channels; D047028:Macrocyclic Compounds / Q000737:chemistry*; D008567:Membranes, Artificial; D015394:Molecular Structure; D012492:Salts; D012822:Silicon Dioxide / Q000737:chemistry; D014961:X-Ray Diffraction
D007473:Ion Channels; D047028:Macrocyclic Compounds; D008567:Membranes, Artificial; D012492:Salts; D012822:Silicon Dioxide