Distortion product otoacoustic emissions in an industrial setting.
Distortion product otoacoustic emissions (DPOAEs) is an objective sensitive test of cochlear function. The aim of this study was the evaluation of noise-induced hearing loss in a group of industrial workers, using this method in conjunction with standard puretone audiometry (PTA). One hundred and five subjects (210 ears) were included in the study. PTA, tympanometry, and DPOAEs were performed. Results were analyzed using a mixed analysis of variance model, and compared with the data of 34 normal persons of similar age and sex. We found statistically significant lower DPOAE levels in the noise-exposed group than in the control group. Additionally, the effect of frequency was significant, indicating that amplitude varied across frequency, with lower responses observed at 4 and 6 kHz, and maximum response found at 2 kHz. PTA showed a statistically significant effect of Group, owed to elevated puretone thresholds in the noise-exposed subjects, but a Frequency main effect was not found, although the interaction between Frequency and Group was statistically significant, as well as the interaction between Frequency and Ear. A main effect for Ear was found only in puretone thresholds, due to better thresholds in the left ears of the subjects, and not in DPOAE measurements. DPOAE levels were selectively affected at the higher frequencies, whereas puretone thresholds were affected at all frequencies. Direct comparison of the number of significantly affected ears between the two methods at 1, 2, and 4 kHz showed statistically significant differences at all comparisons, with more ears affected in PTA in comparison with DPOAEs at 4 kHz, whereas more ears were affected in DPOAEs at the lower frequencies (1 and 2 kHz). Therefore, it may be concluded that DPOAEs and PTA are both sensitive methods in detecting noise-induced hearing loss, with DPOAEs tending to be more sensitive at lower frequencies.
Korres
George S
GS
Department of Otolaryngology, National University of Athens, Hippokration Hospital, Athens.
Balatsouras
Dimitrios G
DG
Tzagaroulakis
Antonis
A
Kandiloros
Dimitris
D
Ferekidou
Elisabeth
E
Korres
Stavros
S
D000328:Adult; D000704:Analysis of Variance; D001301:Audiometry, Pure-Tone; D016022:Case-Control Studies; D003051:Cochlea / Q000473:pathology / Q000502:physiology* / Q000503:physiopathology; D005260:Female; D006198:Hair Cells, Auditory / Q000502:physiology; D006317:Hearing Loss, Noise-Induced / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009623:Noise, Occupational / Q000009:adverse effects*; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D055815:Young Adult