Expression of ghrelin in human fetal adrenal glands and paraadrenal nerve ganglions.
The aim of this paper was assessment of location, expression and role of ghrelin in the development and maturation of human fetal adrenal glands and paraadrenal nerve ganglions. Immunohistochemistry was used. The strongest expression of ghrelin was detected in the fetal zone of the adrenal glands, in the neuroepithelial cells of the medullar portion of the adrenals and in few nerve ganglion cells. Ghrelin takes part in molecular processes of proliferation and maturation, and does not influence on steroidogenesis.
IInd Department of Pediatrics Poznań, University of Medical Sciences, Poznań, Poland.
Monika
M
Obara-Moszyńska
Andrzej
A
Kedzia
Maria
M
Chmielnicka-Kopaczyk
D000311:Adrenal Glands / Q000166:cytology / Q000294:innervation* / Q000378:metabolism*; D005260:Female; D020567:Fetal Weight; D005333:Fetus / Q000166:cytology / Q000378:metabolism*; D005724:Ganglia / Q000166:cytology / Q000378:metabolism*; D005865:Gestational Age; D054439:Ghrelin / Q000378:metabolism*; D006801:Humans; D008297:Male
D054439:Ghrelin