[Comparative assessment of the course of age-related macular degeneration in patients after phacoemulsification cataract surgery with implantation of AcrySof Natural SN 60 at and AcrySof SA 60 at lenses].
OBJECTIVE
To evaluate the influence of AcrySofNatural SN 60 AT lens on the progression of age-related macular degeneration (AMD).


METHODS
Forty eyes of 20 patients (12 women and 8 men, mean age of 74 years) with bilateral cataract and age-related macular degeneration were analyzed. In both eyes (3 weeks interval) cataract surgery with intraocular lens implantation was performed. In one eye, the lens with blue light blocking filter 400-500 nm (AcrySof Natural SN 60 AT) was implanted. In the opposite eye, which served as a control, standard (AcrySof SA 60 AT) lens was implanted. To estimate AMD progression after bilateral surgery, the routine ophthalmic examination, fluorescein angiography and multifocal ERG results were performed. After mean 18 months obtained results from eye with AcrySof Natural were compared to the results from the opposite eye.


RESULTS
After surgery (mean follow-up--18 months) in eyes with implantations of AcrySof Natural and standard lenses there were no significant differences in routine ophthalmic examination and fluorescein angiography results. In eyes with implanted AcrySofNatural SN 60 AT lens, in mfERG a significant decrease of central retinal function was observed (p < or = 0.05). In eyes with standard AcrySof lens in mfERG statistical differences of analyzed parameters were not found.


CONCLUSIONS
The results of our study suggest lack of protective influence of AcrySofNatural lens on the AMD progression. Further investigation on the larger group of patients should be performed to confirm our initial results.
Katedra i Klinika Okulistyki Pomorskiej Akademii Medycznej w Szczecinie al. Powstańców Wlkp. 72, 70-111 Szczecin.
Dariusz
D
Łak
Wojciech
W
Lubiński
Zofia
Z
Sylwestrzak
Zbigniew
Z
Szych
Danuta
D
Karczewicz
D000368:Aged; D018450:Disease Progression; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008268:Macular Degeneration / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects*