Synthesis of polysubstituted pyrroles from sulfinimines (N-sulfinyl imines).
Polysubstituted 2-carboxylate and 2-phosphonate pyrroles are prepared by aromatization of the corresponding 3-oxo 2-carboxylate and 2-phosphonate NH-pyrrolidines using air. Reaction of electrophiles with 3-oxo pyrrolidine dianions readily introduces substituents, regioselectively at C-4 in these pyrrolidines.
Davis
Franklin A
FA
Department of Chemistry, Temple University, Philadelphia, PA 19122.
Bowen
Kerisha A
KA
Xu
He
H
Velvadapu
Venkata
V