Three new naphthoquinone pigments isolated from the freshwater fungus, Astrosphaeriella papuana.
Three new naphthoquinones, astropaquinones A-C (1-3), were isolated from cultures of the freshwater fungus Astrosphaeriella papuana YMF 1.01181, together with the known compound, 6-hydroxy-2,4-dimethoxy-7-methylanthraquinone (4). The structures of the compounds were settled mainly by interpretation of their 1D and 2D NMR spectra. Astropaquinone B (2) and C (3) were found to possess a rare pyranonaphthoquinone skeleton containing a lactol ring. Furthermore, compounds 1-4 showed moderate antagonistic activity against nine fungi and four bacterial strains.
Wang
Le
L
Laboratory for Conservation and Utilization of Bio-Resources, and Key laboratory for Microbial Resources of the Chinese Ministry of Education, Yunnan University, Kunming, P. R. China.
Dong
Jin Yan
JY
Song
Hong-Chuang
HC
Shen
Kai Ze
KZ
Wang
Li Mei
LM
Sun
Rong
R
Wang
Chun Ren
CR
Gao
Yan Xiu
YX
Li
Guo Hong
GH
Li
Lei
L
Zhang
Ke Qin
KQ
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009285:Naphthoquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular
D000880:Anthraquinones; D000890:Anti-Infective Agents; D009285:Naphthoquinones; C547033:astropaquinone A; C547034:astropaquinone B; C547035:astropaquinone C