[Esthesioneuroblastoma: a case report and literature review].
Esthesioneuroblastoma (ENB) or olfactive neuroblastoma is a rare cancer arising from the neuroepithelium of the olfactory epithelium of the nasal cavity. Sinusal, orbital and intracranial expansions are common. The anatomopathological diagnosis will frequently require immuno-histochemical tests and sometimes electron-microscopy as well as genetic testing. Medical imaging with CT scan and MRI is essential for the stadification. Treatment will generally associate debulking or curative surgery (with combined rhino-neurosurgical accesses) and conformal stereo-tactic radiotherapy. Chemotherapy was generally reserved for palliative cases; it can be now proposed as neoadjuvant treatment. Most patients will relapse; thus the follow-up will remain ad vitam.
Service d'Oncologie Médicale, CHC, Clinique Saint Joseph, Liège, Belgique.
L
L
Kalala
C
C
Focan
F
F
Schils
R
R
Gilles
F
F
Abraham
P
P
Reginster
D
D
Van Den Berge
D000328:Adult; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000175:diagnosis / Q000628:therapy