Infantile iron poisoning: challenges in diagnosis and management.
OBJECTIVE
To describe the clinical course and treatment of an infant with iron poisoning.


METHODS
Case report.


METHODS
Pediatric intensive care unit in a tertiary care children's hospital.


RESULTS
A 7-week-old, ex-28-week premature infant, was accidentally poisoned with ferrous sulfate. She recovered completely from metabolic acidosis and shock after treatment with inotropes and chelation with deferoxamine, but her management was complicated by challenges of physiologic immaturity of developing organs. This is the youngest infant reported, to date, with iron poisoning resulting in metabolic acidosis and shock.


CONCLUSIONS
This case illustrates the importance of including toxic exposure in the differential diagnosis of neonatal shock of unknown etiology. Because of physiologic immaturity, iron poisoning in young infants poses special diagnostic and therapeutic challenges.
Department of Pediatrics, Wayne State University School of Medicine and Children's Hospital of Michigan, Detroit, MI, USA. kvalenti@med.wayne.edu
Kevin
K
Valentine
Christopher
C
Mastropietro
Ashok P
AP
Sarnaik
D003676:Deferoxamine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D005296:Ferrous Compounds / Q000506:poisoning*; D006801:Humans; D007231:Infant, Newborn; D011041:Poisoning / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome
D005296:Ferrous Compounds; C020748:ferrous sulfate; D003676:Deferoxamine