Total cholesterol content of erythrocyte membranes levels are associated with the presence of acute coronary syndrome and high sensitivity C-reactive protein.
In this study we assessed whether total cholesterol content of erythrocyte membranes (CEM) was associated with the presence of acute coronary syndrome (ACS) and high sensitivity C-reactive protein (hs-CRP). Consecutive angina patients were assessed; 98 had ACS and 45 had stable angina pectoris (SAP). CEM in the ACS group was significantly higher compared with the SAP group (p< 0.05). Multiple logistic regression analyses revealed a significant independent relation between CEM and the presence of ACS (OR 24.990, p<0.001). CEM was positively correlated with serum hs-CRP levels (r=0.328, p<0.001). These findings suggest a potential role of CEM as a marker of vulnerable plaque.
Yu
Mei-mei
MM
Xu
Yan
Y
Zhang
Jian-hua
JH
Wang
Chang-hui
CH
Wang
Xiao-chen
XC
Cheng
Zi-ping
ZP
Xu
Bang-long
BL
D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis; D000787:Angina Pectoris / Q000097:blood / Q000175:diagnosis; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male
D015415:Biomarkers; D002097:C-Reactive Protein; D002784:Cholesterol