High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer.
Vitamin C (ascorbic acid, ascorbate) has a controversial history in cancer treatment. Emerging evidence indicates that ascorbate in cancer treatment deserves re-examination. As research results concerning ascorbate pharmacokinetics and its mechanisms of action against tumor cells have been published, and as evidence from case studies has continued to mount that ascorbate therapy could be effective if the right protocols were used, interest among physicians and scientists has increased. In this review, high-dose vitamin C therapy in cancer treatment is re-evaluated.
Ohno
Satoshi
S
Department of Complementary and Alternative Medicine Clinical R&D, Kanazawa University, Graduate School of Medical Science, Kanazawa, Ishikawa, 920-8640, Japan. satoshio@med.kanazawa-u.ac.jp
Ohno
Yumiko
Y
Suzuki
Nobutaka
N
Soma
Gen-Ichiro
G
Inoue
Masaki
M
D000975:Antioxidants / Q000008:administration & dosage* / Q000009:adverse effects; D001205:Ascorbic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
D000975:Antioxidants; D001205:Ascorbic Acid