Daphenylline, a new alkaloid with an unusual skeleton, from Daphniphyllum longeracemosum.
A new alkaloid, daphenylline (1), with an unprecedented rearranged 22-nor-calyciphylline skeleton, was isolated from the fruits of Daphniphyllum longeracemosum. Its structure and stereochemistry were elucidated on the basis of spectroscopic and computational approaches. A plausible biosynthetic pathway of 1 was also proposed.
Zhang
Qiang
Q
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC.
Di
Ying-Tong
YT
Li
Chun-Shun
CS
Fang
Xin
X
Tan
Cheng-Jian
CJ
Zhang
Zhen
Z
Zhang
Yu
Y
He
Hong-Ping
HP
Li
Shun-Lin
SL
Hao
Xiao-Jiang
XJ
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D031995:Saxifragaceae / Q000737:chemistry*
D000470:Alkaloids; D004365:Drugs, Chinese Herbal; C541594:daphenylline