Biomarkers for early detection of liver cancer: focus on clinical evaluation.
This review summarises the screening methods from hepatic ultrasonography to serological biomarkers for early detection of liver cancer and focuses on evaluation of biomarkers ability. The development of novel biomarkers according to the 5-phase program defined by the Early Detection Research Network (EDRN) is also outlined in this review.
Sun
Stella
S
Department of Surgery, LKS Faculty of Medicine, Jockey Club Clinical Research Centre, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. sunstella1980@yahoo.co.uk
Day
Philip J R
PJ
Lee
Nikki P
NP
Luk
John M
JM
D000818:Animals; D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism; D003952:Diagnostic Imaging; D055088:Early Detection of Cancer; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*; D011859:Radiography; D012698:Serologic Tests
D014408:Biomarkers, Tumor