A population-based study on the association between type 2 diabetes and periodontal disease in 12,123 middle-aged Taiwanese (KCIS No. 21).
OBJECTIVE
We investigated the association between type 2 diabetes mellitus (T2DM) and periodontal disease (PD) in the context of the current periodontal aetiology model.


METHODS
In total, 14,747 community residents aged 35-44 years were invited to a community-based PD survey between 2003 and 2006 using the community periodontal index. Significant factors modifying the association between T2DM and PD were ascertained. We further assessed the association between T2DM and the risk for PD, within strata of significant effect modifiers, after controlling for other putative factors.


RESULTS
The prevalence rate was 10% higher in subjects with T2DM than in those without. After controlling for significant factors, T2DM was positively associated with the risk for PD (adjusted odds ratio=1.34,95% confidence interval: 1.07-1.74). The results of interaction assessment showed that only the waist was identified as a statistically significant effect modifier for such a positive association.


CONCLUSIONS
The association between T2DM and the risk for PD among young adult was demonstrated. This finding, together with other aetiological factors, fit with the current hypothesized model of the aetiology of periodontitis. However, the effect of T2DM modified by waist measurement should be verified in future studies.
Health Bureau of Keelung City, Keelung City, Taiwan.
Ting-Ting
TT
Wang
Tony Hsiu-Hsi
TH
Chen
Po-En
PE
Wang
Hongmin
H
Lai
Ming-Te
MT
Lo
Pearl Yi-Chun
PY
Chen
Sherry Yueh-Hsia
SY
Chiu
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003728:Dental Calculus / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D015987:Effect Modifier, Epidemiologic; D005247:Feeding Behavior; D005260:Female; D005884:Gingival Hemorrhage / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008019:Life Style; D008297:Male; D009765:Obesity / Q000453:epidemiology; D010510:Periodontal Diseases / Q000453:epidemiology*; D010514:Periodontal Pocket / Q000453:epidemiology; D011159:Population Surveillance; D011236:Prediabetic State / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D014280:Triglycerides / Q000097:blood
D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol