Modulation of the jaw-opening reflex by stimulation of the vestibular nuclear complex in rats.
The effect of stimulation of the vestibular nuclear complex (VN) on the jaw-opening reflex (JOR) was studied in anesthetized rats. The JOR was evoked by electrical stimulation of the inferior alveolar nerve, and was recorded as the electromyographic responses of the anterior belly of the digastric muscle, bilaterally. Conditioning electrical stimulation of the medial (MVN), lateral (LVN) and superior (SVN) vestibular nuclei facilitated the JOR bilaterally. Microinjection of monosodium glutamate into the SVN, LVN and MVN also facilitated the JOR bilaterally. In contrast, conditioning electrical stimulation of the inferior vestibular nucleus (IVN) inhibited the JOR ipsilaterally. Microinjection of monosodium glutamate into the IVN also inhibited the JOR ipsilaterally. These results suggest that the VN is involved in modulation of the JOR and plays an important role in controlling the jaw movements.
Satoh
Yoshihide
Y
Department of Physiology, The Nippon Dental University School of Life Dentistry at Niigata, 1-8 Hamaura-cho, chuou-ku, Niigata, Japan. ysatoh@ngt.ndu.ac.jp
Ishizuka
Ken'ichi
K
Murakami
Toshiki
T
D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D004558:Electric Stimulation / Q000379:methods; D007568:Jaw / Q000294:innervation* / Q000502:physiology*; D008297:Male; D008409:Mastication / Q000502:physiology*; D008410:Masticatory Muscles / Q000294:innervation* / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011930:Reaction Time; D012018:Reflex / Q000502:physiology*; D014726:Vestibular Nuclei / Q000502:physiology*