[Dynamics of neurodegenerative processes and lifespan under the action of Cerebral combined with other pharmaceuticals in Drosophila melanogaster mutants].
Effective influence of the drug Cerebral and its micro- and macrofractions on the mean lifespan and degenerative process dynamics of Drosophila melanogaster have been investigated. No dose--effect dependence was detected when different concentrations of Cerebral were used. The administration of Cerebral as a neuroactivating remedy combined with piracetam and verapamil was most effective, leading to an increase in the lifespan and a delay in the appearance of brain degenerative processes.
Plakhta
E L
EL
Kushnir
A G
AG
Maksimov
D V
DV
Makarenko
A N
AN
Golub
N Ia
NIa
Chernik
Ia I
IaI
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000473:pathology; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology*; D008136:Longevity / Q000187:drug effects*; D009154:Mutation; D009474:Neurons / Q000187:drug effects* / Q000473:pathology; D018696:Neuroprotective Agents / Q000494:pharmacology*; D010455:Peptides / Q000494:pharmacology*; D010889:Piracetam / Q000494:pharmacology
D018696:Neuroprotective Agents; D010455:Peptides; D010889:Piracetam