Genomic and biochemical analysis of N glycosylation in the mushroom-forming basidiomycete Schizophyllum commune.
N-linked glycans of Schizophyllum commune consist of Man(5-9)GlcNAc(2) structures. Lack of further glycan maturation is explained by the absence of genes encoding such functions in this and other homobasidiomycetes. N-linked glycans in vegetative mycelium and fruiting bodies of S. commune are mainly Man(7)GlcNAc(2) and Man(5)GlcNAc(2), respectively, suggesting more efficient mannose trimming in the mushroom.
Molecular Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Institute of Biomembranes, Utrecht University, The Netherlands. E.Berends@uu.nl
Elsa
E
Berends
Robin A
RA
Ohm
Jan F
JF
de Jong
Gerard
G
Rouwendal
Han A B
HA
Wösten
Luis G
LG
Lugones
Dirk
D
Bosch
D005800:Genes, Fungal; D006031:Glycosylation; D006801:Humans; D008358:Mannose / Q000378:metabolism; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism; D012567:Schizophyllum / Q000235:genetics / Q000378:metabolism*
D009584:Nitrogen; D008358:Mannose