Pain remapping in migraine: a novel characteristic following trigeminal nerve injury.
The location of pain during the headache phase of migraine varies between individuals as well as between attacks in some individuals. We have observed a "remapping" or a change in the location of migraine pain following injury to the trigeminal system that is a novel characteristic to migraine and has not been described in other trigeminal pain syndromes of the head, neck, and face. Recognition of this clinical feature implies that the pathophysiology of migraine is impressionable and may be why diagnosis and treatment are often delayed.
Hussain
Aamir
A
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Stiles
Marlind A
MA
Oshinsky
Michael L
ML
D000328:Adult; D000344:Afferent Pathways / Q000503:physiopathology; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control; D005151:Facial Injuries / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000150:complications / Q000503:physiopathology; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D009473:Neuronal Plasticity / Q000502:physiology; D053591:Referred Pain / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D014098:Toothache / Q000209:etiology / Q000503:physiopathology; D016896:Treatment Outcome; D014275:Trigeminal Caudal Nucleus / Q000503:physiopathology; D014276:Trigeminal Nerve / Q000503:physiopathology*; D061221:Trigeminal Nerve Injuries; D014277:Trigeminal Neuralgia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D014363:Tryptamines / Q000627:therapeutic use
D000929:Antidepressive Agents, Tricyclic; D014363:Tryptamines