Prospective memory in Parkinson disease across laboratory and self-reported everyday performance.
Prospective memory is a complex cognitive construct ubiquitous in everyday life that is thought to sometimes rely on executive skills commonly affected by Parkinson's disease (PD). The present study investigated the effect of PD on prospective memory tasks with varying demand on executive control processes, namely on the amount of strategic attentional monitoring required for intention retrieval. Individuals with PD but without dementia and healthy adults performed laboratory event-based prospective memory tasks that varied in whether strategic attentional monitoring (nonfocal condition) or spontaneous processes (focal condition) were primarily involved in intention retrieval. Participants also completed a questionnaire rating their frequency of prospective memory failures in everyday life for both self-cued and environment-cued tasks. PD participants performed worse than non-PD participants in the nonfocal, but not focal, condition of the laboratory task. They also reported more everyday failures than non-PD participants for self-cued, but not environment-cued, prospective memory tasks. Thus, nondemented individuals with PD are preferentially impaired on prospective memory tasks for which higher levels of executive control are needed to support intention retrieval. This pattern is consistent across laboratory and reported real-world performance.
Department of Neurology, Program in Occupational Therapy, Washington University in St Louis, St Louis, MO 63110, USA. erfoster@wustl.edu
Erin R
ER
Foster
Mark A
MA
McDaniel
Grega
G
Repovs
Tamara
T
Hershey
D000368:Aged; D003463:Cues; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000523:psychology*; D008570:Memory, Short-Term; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D011340:Problem Solving; D011597:Psychomotor Performance; D011930:Reaction Time; D011795:Surveys and Questionnaires; D013647:Task Performance and Analysis; D014706:Verbal Learning