[Primary hyperparathyroidism].
Primary hyperparathyroidism is frequent. Most new cases are diagnosed in post-menopausal women, and are mildly progressive. Surgery is imperative for patients under 50, for symptomatic patients, especially with osteoporosis. Familial hyperparathyroidism can be related to mutations of the menin (MEN1), Ret (MEN2), HRPT 1 and 2 genes or calcium sensor, and have different management, work-up and prognosis.
Clinique Endocrinologique Marc Linquette, CHU de Lille, 6 rue du Professeur Laguesse, 59037 Lille cedex, France. jl-wemeau@chru-lille.fr
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D000367:Age Factors; D003720:Densitometry; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D049950:Hyperparathyroidism, Primary / Q000175:diagnosis / Q000235:genetics / Q000601:surgery / Q000628:therapy; D008297:Male; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000235:genetics; D018813:Multiple Endocrine Neoplasia Type 2a / Q000235:genetics; D009154:Mutation; D010024:Osteoporosis / Q000175:diagnosis / Q000209:etiology; D011379:Prognosis