MR-compatible polyetheretherketone-based guide wire assisting MR-guided stenting of iliac and supraaortic arteries in swine: feasibility study.
The purpose of this study was to demonstrate first magnetic resonance (MR)-guided stenting of iliac and supraaortic arteries using a polyetheretherketone-based (PEEK) MR-compatible guide wire. In vitro and animal experiments were performed in a short magnet wide-bore scanner (1.5 Tesla, Espree, Siemens Healthcare, Erlangen, Germany). For all experiments, a 0.035'' MR-compatible guide wire prototoype was used. This wire had a compound core of PEEK with reinforcing fibres, a soft and atraumatic tip and a hydrophilic coating. For its passive visualization, paramagnetic markings were attached. All experiments were performed through a vascular introducer sheath under MR-guidance. In vitro repetitive selective over the wire catheterizations of either the right carotid artery and the left subclavian artery were performed. In vivo, selective catheterization and over-the-wire stenting of the brachiocephalic trunk and the left subclavian artery were performed. The common iliac arteries were catheterized retrogradely (left) and cross-over (right). Angioplasty and stenting were performed over-the-wire. All procedures were successful. Visibility of the PEEK-based guide-wire was rated good in vitro and acceptable in vivo. Guide wire pushability and endovascular device support were good. The PEEK-based MR-compatible guide wire is well visible and usable under MR-guidance. It supports over-the-wire treatment of iliac arteries and supraaortic arteries.
Institute of Radiology, University of Basel Hospital, Basel, Switzerland. skos@gmx.de
Sebastian
S
Kos
Rolf
R
Huegli
Eugen
E
Hofmann
Harald H
HH
Quick
Hilmar
H
Kuehl
Stephanie
S
Aker
Gernot M
GM
Kaiser
Paul J A
PJ
Borm
Augustinus L
AL
Jacob
Deniz
D
Bilecen
D017130:Angioplasty / Q000379:methods; D000818:Animals; D001011:Aorta / Q000601:surgery; D001577:Benzophenones; D001672:Biocompatible Materials; D016122:Brachiocephalic Trunk / Q000601:surgery; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D005260:Female; D007083:Iliac Artery / Q000601:surgery; D007659:Ketones; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D011092:Polyethylene Glycols; D011108:Polymers; D015607:Stents; D013348:Subclavian Artery / Q000601:surgery; D013552:Swine
D001577:Benzophenones; D001672:Biocompatible Materials; D007659:Ketones; D011108:Polymers; C063834:polyetheretherketone; D011092:Polyethylene Glycols