[Effect of cyclopentyladenosine on the orientation, exploratory, and emotional behavior of rats with model brain injury].
Effects of a local compression brain injury and the preventive application of cyclopentyladenosine (CPA) on the behavior of rats in the open field test was investigated. It is established that the local injury of a parietal cortex causes intensification of the orientation--research behavior and an increase in the emotional stress in rats. A protective action of CPA was manifested by a decrease in the expressiveness and duration of disturbances in the emotional and orientation--research behavior of animals in the open field test.
Sufianova
G Z
GZ
Sufianov
A A
AA
Shapkin
A G
AG
Usov
L A
LA
D000241:Adenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D058916:Adenosine A1 Receptor Antagonists; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001930:Brain Injuries / Q000523:psychology*; D004195:Disease Models, Animal; D004644:Emotions / Q000187:drug effects*; D005106:Exploratory Behavior / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male; D009949:Orientation / Q000187:drug effects*; D051381:Rats
D058916:Adenosine A1 Receptor Antagonists; C048599:N(6)-cyclopentyladenosine; D000241:Adenosine