PIDA-mediated oxidative C-C bond formation: novel synthesis of indoles from N-aryl enamines.
A variety of functionalized indoles were synthesized from N-aryl enamines via PIDA-mediated oxidative carbon-carbon bond formation. The features of the present reaction include facilitative preparation of substrates 2, good functional group tolerance, and mild reaction conditions without transition metals.
Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Wenquan
W
Yu
Yunfei
Y
Du
Kang
K
Zhao
D000085:Acetates / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000085:Acetates; D000588:Amines; D001555:Benzene Derivatives; D007211:Indoles; D007462:Iodobenzenes