A microreactor with thousands of subcompartments: enzyme-loaded liposomes within polymer capsules.
Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes-liposome-compartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system.
Städler
Brigitte
B
Centre for Nanoscience and Nanotechnology, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.
Chandrawati
Rona
R
Price
Andrew D
AD
Chong
Siow-Feng
SF
Breheney
Kerry
K
Postma
Almar
A
Connal
Luke A
LA
Zelikin
Alexander N
AN
Caruso
Frank
F
D002214:Capsules; D008081:Liposomes / Q000737:chemistry*; D017830:Octoxynol / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D001618:beta-Lactamases / Q000737:chemistry* / Q000378:metabolism
D002214:Capsules; D008081:Liposomes; D011108:Polymers; D017830:Octoxynol; D001618:beta-Lactamases