Umbilical cord stem cell transplantation.
OBJECTIVE
To discuss the history, current state, and future directions of umbilical cord blood (UCB) transplantation as it relates to the emerging field of cellular therapies.


METHODS
Research studies, articles, and personal experiences.


CONCLUSIONS
Transplantation using hematopoietic stem cells from UCB is a life-saving option for patients with select oncologic and immunologic diseases, bone marrow failure, hemoglobinopathies, and inborn errors of metabolism.
Duke Pediatric Blood and Marrow Transplant Unit, NC, USA. frey0004@mc.duke.edu
Michelle A
MA
Frey
Catherine
C
Guess
June
J
Allison
Joanne
J
Kurtzberg
D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods* / Q000451:nursing / Q000639:trends; D005544:Forecasting; D006801:Humans; D009859:Oncology Nursing; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods / Q000451:nursing; D019172:Transplantation Conditioning / Q000379:methods; D014181:Transplantation Immunology; D016896:Treatment Outcome; D014470:Umbilical Cord / Q000166:cytology