The Effect of the AcrySof natural lens on glare disability and photostress.
OBJECTIVE
To investigate whether implanting "blue-filtering" yellow intraocular lenses (IOL) could provide a visual benefit in terms of glare disability and photostress recovery.


METHODS
A case-control study.


METHODS
Researchers masked to group assignments tested 58 subjects: 17 with yellow IOLs (AcrySof Natural; SN60WF; Alcon Laboratories Inc, Fort Worth, Texas, USA), 20 with clear IOLs, and 21 phakic controls. Photostress recovery and visual acuity under veiling glare conditions were assessed in a Maxwellian view optical system. Photostress recovery was assessed by measuring the time required to detect a grating stimulus (1 degree diameter) after a 5-second exposure to an intense circular disk (1 degree diameter) of broad-band xenon light. For the veiling glare experiment, subjects fixated on the grating stimulus, and the intensity of a broad-band xenon annulus (the glare source, 10 degrees inner, 12 degrees outer diameter) was adjusted until the grating stimulus was no longer seen.


RESULTS
Subjects with AcrySof Natural (P < .0001) and clear IOLs (P < .035) could withstand significantly more light than the phakic controls. Subjects with the AcrySof Natural lens could withstand significantly more light (P < .02) than subjects with clear IOLs. Photostress recovery was significantly longer for subjects with clear IOLs vs phakic controls (P < .01), but the AcrySof Natural lens was not different from phakic controls (P < .09). Photostress recovery was similar between subjects with clear or AcrySof Natural lens (P < .32).


CONCLUSIONS
The AcrySof Natural lens is related to reduced glare disability relative to a clear IOL or phakic controls.
Vision Sciences Laboratory, University of Georgia, Athens, GA 30602, USA. bhammond@uga.edu
Billy R
BR
Hammond
Brad
B
Bernstein
Jing
J
Dong
D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D004185:Disability Evaluation; D005260:Female; D019466:Glare; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D010775:Photic Stimulation; D013312:Stress, Physiological; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000517:prevention & control*; D014792:Visual Acuity
D000180:Acrylic Resins