A new triterpenoid from the leaves of Ficus benjamina (var. comosa).
The benzene extract of the leaves of Ficus benjamina (variety comosa) afforded a new triterpene, named serrat-3-one (Fc-2), along with the known phytoconstituents pentacontanyl decanoate (Fc-1), friedelin and beta-sitosterol. Their structures were established on the basis of chemical and physical evidence (IR, (1)H NMR, (13)C NMR and MS). The aqueous and alcoholic extracts of leaves of F. bejamina showed significant antinociceptive activity in an analgesiometer test.
Parveen
Mehtab
M
Department of Chemistry, Aligarh Muslim University, Aligarh, UP, India. mehtab_organic@rediffmail.com
Ghalib
Raza Murad
RM
Mehdi
Sayed Hasan
SH
Rehman
Syed Ziaur
SZ
Ali
Mohammad
M
D000700:Analgesics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D030681:Ficus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D017933:Peripheral Nervous System / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D051381:Rats; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D000700:Analgesics; D010936:Plant Extracts; D014315:Triterpenes