[A 17 year old adolescent with chronic neutropenia, recurrent infections, severe dysphagia and peroneus palsy].
A 17-year-old German adolescent with a four year history of neutropenia and repeated infections presented with severe dysphagia and progressive right-sided peroneus palsy. In the past four years, extensive medical workup had been performed, and despite conspicuous findings, no diagnosis was made. Finally we diagnosed HIV related CMV esophagitis and HIV associated polyneuropathy. The CMV esophagitis was treated antivirally, and highly active antiretroviral HIV therapy was initiated. The mode of HIV transmission remained obscure until further research revealed a probable nosocomial infection during early childhood in Romania.
II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstrasse 22, Munich, Germany. thomas.sternfeld@lrz.tum.de
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Sternfeld
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Weidenbach
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Lorenzen
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Schmid
D000293:Adolescent; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003680:Deglutition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D004941:Esophagitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D010243:Paralysis / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D020427:Peroneal Neuropathies / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D055502:Secondary Prevention
D019380:Anti-HIV Agents