Room-temperature aerobic formation of a stable aryl-Cu(III) complex and its reactions with nucleophiles: highly efficient and diverse arene C-H functionalizations of azacalix[1]arene[3]pyridine.
Under very mild aerobic conditions, azacalix[1]arene[3]pyridine underwent highly efficient C-H activation with Cu(ClO(4))(2).6H(2)O to form a stable aryl-Cu(III) complex which reacted rapidly with various nucleophiles at ambient temperature to afford diverse functionalized azacalix[1]arene[3]pyridine derivatives in excellent yields.
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Bo
B
Yao
De-Xian
DX
Wang
Zhi-Tang
ZT
Huang
Mei-Xiang
MX
Wang