A case of herpetic epithelial keratitis after triamcinolone acetonide subtenon injection.
BACKGROUND
We report a case of herpes simplex virus (HSV) epithelial keratitis that developed after a subtenon triamcinolone acetonide (TA) injection.


METHODS
A 78-year-old woman with a branch retinal vein occlusion and diffuse macular edema in her left eye received a subtenon injection of 20 mg of TA.


RESULTS
Six days after the injection, the patient presented with a foreign body sensation, tearing, redness, and photophobia in the same eye. Slit-lamp examination revealed multiple corneal dendriform ulcers. She was diagnosed with HSV epithelial keratitis and treated with topical acyclovir ointment. The epithelial lesions healed after 1 week of therapy.


CONCLUSIONS
HSV epithelial keratitis can be a possible complication of a TA subtenon injection.
Hashizume
Kouhei
K
Department of Ophthalmology, Iwate Medical University, School of Medicine, Iwate, Japan. hassy_and_yumiyumi@nifty.com
Nabeshima
Takashi
T
Fujiwara
Takamitsu
T
Machida
Shigeki
S
Kurosaka
Daijiro
D
D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D019573:Epithelium, Corneal / Q000821:virology*; D005205:Fascia; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D018259:Herpesvirus 1, Human / Q000502:physiology*; D006801:Humans; D007267:Injections; D016849:Keratitis, Herpetic / Q000188:drug therapy / Q000209:etiology*; D008269:Macular Edema / Q000188:drug therapy / Q000209:etiology; D012170:Retinal Vein Occlusion / Q000150:complications / Q000188:drug therapy; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014775:Virus Activation / Q000187:drug effects
D000998:Antiviral Agents; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D000212:Acyclovir