Effect of ABCG2, PPARGC1A, OLR1 and SCD1 gene polymorphism on estimated breeding values for functional and production traits in Polish Holstein-Friesian bulls.
This study investigated the impact of 6 polymorphisms located in the ABCG2, PPARGC1A, OLR1 and SCD1 genes on estimated breeding values for milk production, longevity, somatic cell count and reproductive traits. The analysis was conducted on 453 Polish Holstein-Friesian bulls. Genotypes were identified using PCR-RFLP, and haplotype inferences were performed for 3 linked mutations of PPARGC1A. The most significant associations were found between the A/C polymorphism located in exon 14 of ABCG2 and milk fat production traits as well as calving-to-first insemination interval, and between the T/C substitution in intron 9 of the PPARGC1A and non-return rate in heifers.
Komisarek
J
J
Department of Cattle Breeding and Milk Production, Poznan University of Life Sciences, Poznan, Poland. komisjol@jay.au.poznan.pl
Dorynek
Z
Z
D018528:ATP-Binding Cassette Transporters / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D001947:Breeding; D002417:Cattle / Q000235:genetics*; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D051131:Receptors, Oxidized LDL / Q000235:genetics*; D013230:Stearoyl-CoA Desaturase / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*
D018528:ATP-Binding Cassette Transporters; D051131:Receptors, Oxidized LDL; D014157:Transcription Factors; C111264:peroxisome-proliferator-activated receptor-gamma coactivator-1; D013230:Stearoyl-CoA Desaturase