A symbol digit modalities test version suitable for functional MRI studies.
The Symbol Digit Modalities Test is an easy test used to assess cognitive impairment in a wide range of neurological diseases, like multiple sclerosis. We adapted the oral version of this cognitive task making it suitable for functional Magnetic Resonance Imaging studies. Symbol Digit Modalities Test performance was associated with increased brain activity in frontal and parietal areas involved in selective attention and working memory functions. These may provide the basis for future studies assessing potential abnormal cortical activations in multiple sclerosis patients and other clinical populations.
Forn
Cristina
C
Dept. Psicología Bàsica, Clínica i Psicobiología, Universitat Jaume I, Castelló, Spain. forn@psb.uji.es
Belloch
Vicente
V
Bustamante
Juan Carlos
JC
Garbin
Gabrielle
G
Parcet-Ibars
María Antonia
MA
Sanjuan
Ana
A
Ventura
Noelia
N
Avila
César
C
D000328:Adult; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D003072:Cognition Disorders / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications; D009483:Neuropsychological Tests