Reusable, compression-sealed fluid cells for surface mounting to planar substrates.
We have developed a universal structure and mechanism for the repeatable, rapid-attachment of a fluid cell to a planar substrate. The fluid cell and all fluidic connections are completely contained in a plastic body such that attachment requires neither adhesives nor modification of the substrate. The geometry of the fluid cell is defined by the active area of the planar substrate (e.g. a sensor array). All required components have been quickly prototyped using Computer Numerical Control (CNC) machining. It is also straight-forward to create an array of fluid cells to attach to a single substrate (e.g. a standard microscope slide). All components are easy to assemble and can be cleaned and reused, making this flexible approach applicable for a wide range of lab-on-a-chip applications.
Tamanaha
Cy R
CR
Naval Research Laboratory, Washington, DC 20375-5342, USA. cy.tamanaha@nrl.navy.mil
Malito
Michael P
MP
Mulvaney
Shawn P
SP
Whitman
Lloyd J
LJ
D004867:Equipment Design; D017743:Equipment Reuse; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D020411:Oligonucleotide Array Sequence Analysis; D011312:Pressure; D020349:Surface Plasmon Resonance