CE-TOF/MS: fundamental concepts, instrumental considerations and applications.
This review discusses the fundamental principles of TOF analyzers and covers the great progress that has been made in this area in recent years (i.e. orthogonal acceleration, reflectron). This paper also gives an overview of applications performed by CE coupled to TOF/MS detection. The main domains of interest include the analysis of biomolecules and natural compounds.
Staub
Aline
A
School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.
Schappler
Julie
J
Rudaz
Serge
S
Veuthey
Jean-Luc
JL
D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods*; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D040901:Proteomics / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization