[Immunosuppression - too strong or too weak?].
A 52 year old patient with immunosuppressive therapy for ANCA-negative vasculitis presented with fever and paraparesis of the legs, laboratory findings displayed high inflammatory markers. The differential diagnosis comprised acute infection, an exacerbation of vasculitis or a drug reaction. Despite meticulous diagnostics, including FDG-PET, no definitive cause for the symptoms could be uncovered. Empirical antibiotic treatment in combination with high doses of glucocorticosteroids lead to prompt resolution of fever and inflammatory laboratory markers.
Schneidewind
A
A
Klinik für Innere Medizin I, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, 93051 Regensburg. arne.schneidewind@klinik.uni-r.de
Fleck
M
M
Salzberger
B
B
Schölmerich
J
J
Ehrenstein
B
B
D005335:Fever of Unknown Origin / Q000139:chemically induced* / Q000517:prevention & control*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D008297:Male; D020335:Paraparesis / Q000139:chemically induced* / Q000517:prevention & control*; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
D007166:Immunosuppressive Agents