PirAB toxin from Photorhabdus asymbiotica as a larvicide against dengue vectors.
We have evaluated Photorhabdus insect-related protein (Pir) from Photorhabdus asymbiotica against dengue vectors. PirAB shows larvicidal activity against both Aedes aegypti and Aedes albopictus larvae but did not affect the Mesocyclops thermocyclopoides predator. PirAB expressed the strongest toxicity compared to PirA, PirB, or the mixture of PirA plus PirB. Whether the presence of an enterobacterial repetitive intergenic consensus sequence in PirAB, but not in PirA, PirB, or the mixture of PirA plus PirB, has any impact on biological control efficacy needs further investigation.
Ahantarig
Arunee
A
Center of Excellence for Vectors and Vector-Borne Diseases, Mahidol University at Salaya, Nakhon Pathom, Thailand.
Chantawat
Nantarat
N
Waterfield
Nicholas R
NR
ffrench-Constant
Richard
R
Kittayapong
Pattamaporn
P
D000330:Aedes / Q000187:drug effects*; D000818:Animals; D001427:Bacterial Toxins / Q000494:pharmacology*; D033342:Copepoda / Q000187:drug effects; D003715:Dengue / Q000517:prevention & control; D004199:Disease Vectors; D023061:Gene Order; D005798:Genes, Bacterial; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D020637:Photorhabdus / Q000737:chemistry*; D016019:Survival Analysis
D001427:Bacterial Toxins; D007306:Insecticides