[Long-term complications after injection of permanent tissue-fillers to the lips].
We present two cases with signs of infection and granulomas seen years after injection of permanent fillers to the lips. These side effects are difficult to treat. They resemble an immunological foreign body response and late-onset infection as well as granuloma and scaring depending on the substance injected. Steroid injections are indicated in case of granuloma, and antibiotics should be used when infection occurs, but surgical excision can be required. It is important to emphasize this condition in order to give patients proper advice prior to treatment and to recognize symptoms.
Herlev Hospital, Plastikkirurgisk Afdeling V. cso@dadlnet.dk
Christian
C
Sneistrup
Lisbet Rosenkrantz
LR
Hölmich
Karin
K
Dahlstrøm
D000179:Acrylates / Q000009:adverse effects*; D000180:Acrylic Resins / Q000009:adverse effects*; D000328:Adult; D001424:Bacterial Infections / Q000209:etiology; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D006099:Granuloma / Q000209:etiology / Q000473:pathology; D006801:Humans; D006820:Hyaluronic Acid / Q000009:adverse effects*; D020100:Hydrogels / Q000009:adverse effects*; D007279:Injections, Subcutaneous; D008046:Lip / Q000473:pathology / Q000601:surgery; D013997:Time Factors
D000179:Acrylates; D000180:Acrylic Resins; C482306:Dermalive; D020100:Hydrogels; C016680:polyacrylamide gels; D006820:Hyaluronic Acid