[E(y)2, the novel component of SAGA/TFTC complex in eucaryotes participates in export of mRNP from nucleus and couples transcription with nuclear pore].
For many years transcription was studied independently from the following stages of gene expression. However the tight connection between different stages of gene expression became evident during the last years. This review discusses the new molecular mechanisms coordinating transcription and mRNA export from the nucleus and coupling of transcription and position of the gene in the nucleus. The new protein E(y)2 which plays an important role in these processes is described.
Kurshakova
M M
MM
Nabirochkina
E N
EN
Georgieva
S G
SG
D021581:Active Transport, Cell Nucleus / Q000502:physiology; D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster; D046912:Multiprotein Complexes / Q000235:genetics / Q000378:metabolism*; D022022:Nuclear Pore / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D012261:Ribonucleoproteins / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000502:physiology*
D029721:Drosophila Proteins; D046912:Multiprotein Complexes; D012333:RNA, Messenger; D012261:Ribonucleoproteins; D014157:Transcription Factors; C423782:e(y)2 protein, Drosophila; C026452:messenger ribonucleoprotein