Four new alkaloid derivatives from Ligularia duciformis.
Four new alkaloids, named 1-(4'-methylpyridazin-5'-yl)butane-1,2,3,4-tetraol (1), 3,9-dimethyl-5-nitropyrido[3,2,1-ij]quinazoline-1,7-dione (2), N,N-di(1-imine-propanyl)propionamidine (3), and 2,7-bis(isopropylimino)-2H,7H-dicyclopentacyclooctene-4,9-diol (4), were isolated from the rhizomes of Ligularia duciformis. Their structures were elucidated by spectral analysis.
Key Laboratory of Modern Chinese Medicines, Ministry of Education; Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing, China. njchaofeng@126.com
Chao-Feng
CF
Zhang
Qiong
Q
Wang
Mian
M
Zhang
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D019659:Asteraceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D027343:Rhizome / Q000737:chemistry
D000470:Alkaloids; D004365:Drugs, Chinese Herbal