A boy with membranous nephropathy after allogeneic bone marrow transplantation.
A 6-year-old boy developed bronchiolitis obliterans organizing pneumonia and nephrotic syndrome 5 months after allogeneic bone marrow transplantation from an unrelated donor for acute lymphoblastic leukemia. His renal biopsy showed membranous nephropathy. He was treated with prednisolone and cyclosporine A. Proteinuria disappeared 3 months after the onset of nephrotic syndrome. To our knowledge, this patient is the youngest case with nephrotic syndrome due to membranous nephropathy after hematopoietic stem cell transplantation.
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan. motoyan@basil.ocn.ne.jp.
Osamu
O
Motoyama
Department of Pediatrics, Toho University Medical Center, Omori Hospital, Tokyo, Japan.
Yumiko
Y
Uchino
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan.
Mika
M
Tokuyama
Department of Pediatrics, Social Insurance Sagamino Hospital, Kanagawa, Japan.
Kikuo
K
Iitaka
Department of Pediatrics, Toho University Medical Center, Omori Hospital, Tokyo, Japan.
Akira
A
Ohara
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002675:Child, Preschool; D015433:Glomerulonephritis, Membranous / Q000209:etiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D014184:Transplantation, Homologous / Q000009:adverse effects*