[Thymic carcinoma involving aortic arch; report of a case].
Adenocarcinoma of the thymus is a very rare malignant tumor. The standard treatment for advanced thymic carcinoma has not yet been established, and the prognosis is poor. We report a case of thymic carcinoma that involving the aortic arch and the innominate vein. A 78-year-old woman was admitted to our hospital complaining of hoarseness in April 2007. The computed tomography (CT) scan showed an anterior mediastinal tumor contiguous to the aortic arch and the innominate vein with swelling lymphnodes. Microspcopic examinations of specimens obtained by CT-guided needle biopsy revealed poorly differenciated adenocarcinoma. The carcinoembryonic antigen (CEA) level of serum elevated at 54.9 ng/ml. Thymic carcinoma was diagnosed. The chemoradiotherapy [concurrent, carboplatin (CBDCA) + paclitaxel(TXL)-->vinorelbine (NVB), 60 Gy] was performed, but the effect of the therapy was limited. The resection of the tumor with a part of aortic arch and other peripheral tissues was performed in Augast 2007. The postoperative course was uneventful and the CEA level of serum lowered to the normal. She was discharged 30 days after surgery.
Noriyuki
Toshio
T
Department of General Thoracic Surgery, Onomichi General Hospital, Onomichi, Japan.
Hamamoto
M
M
Takazawa
Y
Y
Katoh
K
K
Hashimoto
M
M
Kuranishi
F
F
Nakahara
M
M
Fukuda
T
T
Ishizaki
Y
Y
Okuda
H
H
Akimoto
E
E
Yonehara
S
S
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D000368:Aged; D001013:Aorta, Thoracic / Q000473:pathology*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D013953:Thymus Neoplasms / Q000473:pathology* / Q000601:surgery* / Q000628:therapy