Foaling rates and risk factors for abortion in pregnant mares presented for medical or surgical treatment of colic: 153 cases (1993-2005).
The purpose of this study was to determine foaling rates in mares presented for medical or surgical treatment of colic, and to examine risk factors associated with abortion following colic. A retrospective analysis of 153 medical records found that mares treated surgically for colic (P = 0.0007) were 3.5 times more likely to have a negative pregnancy outcome than were mares treated medically for colic. Anesthetic time (P = 0.01) and intra-operative hypotension (P = 0.03) were significantly associated with negative pregnancy outcome. Mares with an anesthetic time > or = 3 h were 6 times more likely to abort. Signs of endotoxemia (P = 0.30), hypoxia (P = 0.89), flunixin meglumine administration (P = 0.13), mucous membrane color at the time of presentation (P = 0.82) and capillary refill time (P = 0.76) were not associated with pregnancy outcome. There was no difference in the foaling rate for mares that had received progestin supplementation versus those that had not (P = 0.42). In this study, the significant risk factors for abortion were surgically treated colic, long anesthetic time, and intraoperative hypotension.
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1. tchenier@uoguelph.ca
Tracey S
TS
Chenier
Ashley E
AE
Whitehead
D000034:Abortion, Veterinary / Q000453:epidemiology / Q000209:etiology; D000758:Anesthesia / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D003085:Colic / Q000503:physiopathology / Q000601:surgery / Q000628:therapy / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D006736:Horses; D007022:Hypotension / Q000503:physiopathology / Q000662:veterinary*; D000860:Hypoxia / Q000503:physiopathology / Q000662:veterinary; D007431:Intraoperative Complications / Q000662:veterinary; D011247:Pregnancy; D011248:Pregnancy Complications / Q000662:veterinary*; D011256:Pregnancy Outcome / Q000662:veterinary; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome