[Cerebrovascular disorders and central hemodynamics of Takayasu disease].
The results of the study of 45 patients with Takayasu arteritis using the complex clinical-neurological and instrumental examination are presented. Cerebrovascular disorders and defects of the white and grey matter were registered in 84.4% patients. The immunological study of CSF was done for 6 patients. All changes revealed that the mechanisms of development of vasculitis in this pathology are related to the humoral and cellular autoimmune reaction to vessel wall antigens in patients with Takayasu disease. The neurological manifestation may be initial, relating to the development of the disease as such, and secondary, i.e., the result of the damage of other organs and systems.
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D000328:Adult; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D013625:Takayasu Arteritis / Q000150:complications* / Q000276:immunology*