A cross-sectional relationship between vital capacity and diabetes in Japanese men.
OBJECTIVE
The aim of the present study was to examine the cross-sectional relationship between vital capacity and diabetes, metabolic syndrome (MS), and high-sensitivity C-reactive protein (hs-CRP) among Japanese men.


METHODS
Medical check-up data of 1353 men were examined. Spearman's correlation coefficients between respiratory function and MS-related risk factors were calculated excluding subjects with hypoglycemic medication. The prevalence of diabetes and MS were compared between subjects with the lowest and the highest quartiles of % vital capacity (%VC). Area under receiver operating characteristic curve (AUC) were calculated for risk factors excluding fasting glucose. Logistic regression using diabetes as a dependent variable and %VC and MS-related risk factors excluding fasting glucose as independent variables was performed.


RESULTS
%VC was significantly correlated with some components of MS and hs-CRP. The prevalence of diabetes, MS, and MS components other than blood pressure were significantly lower in the highest quartile than in the lowest quartile of %VC. AUC of -%VC was highest among MS-related risk factors excluding fasting glucose though statistically not significant. %VC was an independent marker of diabetes in the multivariable logistic regression analysis.


CONCLUSIONS
Vital capacity was an independent marker of diabetes and associated with MS and hs-CRP in Japanese men.
Oda
Eiji
E
Medical Check-up Center, Tachikawa Medical Center, Nagacho 2-2-16, Nagaoka, Niigata 940-0053, Japan. ijie@venus.sannet.ne.jp
Kawai
Ryu
R
D000328:Adult; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012727:Sex Characteristics; D014797:Vital Capacity / Q000502:physiology*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D002097:C-Reactive Protein