Rapid glucose detection by surface enhanced Raman scattering spectroscopy.
An approach to reject stray light and improve glucose adsorption was presented. With a self-assembled monolayer (SAM) and a confocal optical configuration applied in this approach, the adsorption and signal to noise ratio (SNR) have been improved respectively. Our experimental results demonstrated that the surface enhanced Raman scattering (SERS) spectroscopy with 9 feature peaks for 100 mM aqueous glucose is successfully obtained in a dry environment in response time as fast as 40 s only. This approach could improve glucose detection in response time and sensitivity effectively in atmosphere environment.
State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Science, P. O. Box 350, Chengdu 610209, China.
Lanying
L
Yang
Chunlei
C
Du
Xiangang
X
Luo
D000327:Adsorption; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D000441:Hexanols / Q000138:chemical synthesis* / Q000737:chemistry; D054118:Nanospheres / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000295:instrumentation / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors
D000441:Hexanols; D011137:Polystyrenes; D013438:Sulfhydryl Compounds; D012834:Silver; D005947:Glucose; C477019:3-mercaptohexanol