[NT-proBNP in practice: from chemistry to medicine].
Since introduction of routine assay for natriuretic peptides, there are a growing number of clinical applications for those new tests. Numerous studies have defined analytical characteristics and clinical interest of NT-proBNP assay. Originally limited to acute heart failure diagnosis in the emergency room, NT-proBNP assay has now a wide number of applications. This review presents the "state of art" of this marker, detailing NT-proBNP physiological recent knowledge and its recognized or investigated clinical applications.
Service de cardiologie, CH René Dubos, Pontoise.
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Jourdain
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Lefèvre
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Oddoze
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Sapin
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F
Dievart
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G
Jondeau
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C
Meune
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M
Galinier
D054058:Acute Coronary Syndrome / Q000097:blood / Q000175:diagnosis; D000208:Acute Disease; D004355:Drug Stability; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood* / Q000378:metabolism / Q000627:therapeutic use; D010446:Peptide Fragments / Q000097:blood* / Q000378:metabolism / Q000627:therapeutic use; D011498:Protein Precursors / Q000097:blood* / Q000378:metabolism / Q000627:therapeutic use; D012680:Sensitivity and Specificity
D010446:Peptide Fragments; D011498:Protein Precursors; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain