A boy with membranous nephropathy after allogeneic bone marrow transplantation.
A 6-year-old boy developed bronchiolitis obliterans organizing pneumonia and nephrotic syndrome 5 months after allogeneic bone marrow transplantation from an unrelated donor for acute lymphoblastic leukemia. His renal biopsy showed membranous nephropathy. He was treated with prednisolone and cyclosporine A. Proteinuria disappeared 3 months after the onset of nephrotic syndrome. To our knowledge, this patient is the youngest case with nephrotic syndrome due to membranous nephropathy after hematopoietic stem cell transplantation.
Motoyama
Osamu
O
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan. motoyan@basil.ocn.ne.jp.
Uchino
Yumiko
Y
Department of Pediatrics, Toho University Medical Center, Omori Hospital, Tokyo, Japan.
Tokuyama
Mika
M
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan.
Iitaka
Kikuo
K
Department of Pediatrics, Social Insurance Sagamino Hospital, Kanagawa, Japan.
Ohara
Akira
A
Department of Pediatrics, Toho University Medical Center, Omori Hospital, Tokyo, Japan.
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002675:Child, Preschool; D015433:Glomerulonephritis, Membranous / Q000209:etiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D014184:Transplantation, Homologous / Q000009:adverse effects*