Intraoperative cell salvage versus allogeneic transfusion during abdominal aortic surgery: clinical and financial outcomes.
The objective of this study was to assess the clinical and financial outcomes of intraoperative cell salvage (ICS) during abdominal aortic surgery. In this study, 90 patients were operated on with the use of ICS (group 1, prospective) and 90 patients without ICS (group 2, historical control). According to the type of operation, the patients were subdivided into three consecutive 30-patient subgroups (1, aortoiliac occlusive disease [AOD]; 2, elective abdominal aortic aneurysm [AAA]; or 3, ruptured abdominal aortic aneurysm [RAAA]). Transfusion requirements and postoperative complications were recorded. The total amounts of perioperatively transfused allogeneic blood were higher in all patient subgroups that underwent surgery without ICS (p = .0032). In the ICS group, 50% of AOD patients and 60% of elective AAA patients received no allogeneic transfusions. There were no significant differences in the incidence of postoperative complications in any group examined. ICS significantly reduced the necessity for allogeneic transfusions during abdominal aortic surgery. ICS use was most valuable in urgent situations with high blood losses, such as RAAA, for which only small amounts of allogeneic blood were initially available. In patients with more than 3 units of autologous blood reinfused, this method was cost effective.
Clinic for Vascular Surgery, Institute for Cardiovascular Diseases, Clinical Centre of Serbia, Belgrade, Serbia. drmiroslav@gmail.com
Miroslav
M
Marković
Lazar
L
Davidović
Nebojsa
N
Savić
Radomir
R
Sindjelić
Tatjana
T
Ille
Marko
M
Dragas
D000368:Aged; D000704:Analysis of Variance; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D016063:Blood Loss, Surgical; D001803:Blood Transfusion / Q000191:economics / Q000379:methods*; D001804:Blood Transfusion, Autologous / Q000191:economics / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D016896:Treatment Outcome