A sore throat--potentially life-threatening?
A sore throat, which is most commonly viewed as a minor ailment, can be a manifestation of a life-threatening disorder known as Lemierre's syndrome caused by Fusobacterium necrophorum. We report a new case of Lemierre's syndrome that occurred in an otherwise healthy 18-year-old woman, who initially presented with fever and sore throat. The diagnosis was not made until a week later when blood cultures became available. This syndrome should be suspected until proven otherwise in any patient with signs of pharyngitis, a painful swollen neck, and pulmonary symptoms. By presenting this curable, but potentially life-threatening case of Lemierre's syndrome, we hope to increase the awareness of the early clinical manifestations of Lemierre's syndrome and to emphasize the importance of careful physical examination with special attention to the neck. Clinicians should be aware that exclusion of streptococcal infection in a patient with severe tonsillar infection does not exclude a bacterial cause.
Department of Medicine, University of Tennessee, College of Medicine, Chattanooga, TN, USA. hyli720@yahoo.com
Hai-Yan
HY
Li
Mandy
M
Grubb
Mukta
M
Panda
Roger
R
Jones
D000293:Adolescent; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005674:Fusobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D005675:Fusobacterium necrophorum; D006801:Humans; D010400:Penicillin G / Q000627:therapeutic use; D010612:Pharyngitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D014069:Tonsillitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery
D000900:Anti-Bacterial Agents; D000658:Amoxicillin; D010400:Penicillin G