[Muscle relaxants in the ICU].
Neuromuscular blockade in ICU patients has become less popular, in particular since non-invasive methods of artificial respiration have been introduced. Succinylcholine has numerous side effects. Due to its short onset, Rocuronium may be an alternative. The advantage of Atracurium and Cis-Atracurium is a largely organ-independent metabolism. In ICU patients, neuromuscular monitoring should be applied. Prolonged action and critical illness neuropathy are the most prominent side effects of neuromuscular blockade.
Schneider
Gerhard
G
Klinik für Anaesthesiologie, Klinikum rechts der Isar der Technischen Universität München. g.schneider@lrz.tumuenchen.de
D000732:Androstanols / Q000009:adverse effects / Q000627:therapeutic use; D001279:Atracurium / Q000009:adverse effects / Q000627:therapeutic use*; D016638:Critical Illness; D006801:Humans; D007036:Hypothermia, Induced; D007362:Intensive Care Units; D009045:Motor Endplate / Q000187:drug effects; D009422:Nervous System Diseases / Q000139:chemically induced; D019148:Neuromuscular Blockade / Q000379:methods*; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects / Q000627:therapeutic use*; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects / Q000627:therapeutic use*; D011014:Pneumonia / Q000139:chemically induced; D000077123:Rocuronium; D018805:Sepsis / Q000517:prevention & control; D013390:Succinylcholine / Q000009:adverse effects / Q000627:therapeutic use*; D013923:Thromboembolism / Q000139:chemically induced / Q000517:prevention & control; D014673:Vecuronium Bromide / Q000009:adverse effects / Q000627:therapeutic use
D000732:Androstanols; D009466:Neuromuscular Blocking Agents; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium; D014673:Vecuronium Bromide; D013390:Succinylcholine; D000077123:Rocuronium