Drug-induced hypersensivity syndrome associated with Epstein-Barr virus infection: a pediatric case report.
Drug hypersensitivity syndrome is an acute, severe, multi-organ systemic reaction, usually developing with aromatic antiepileptic drugs. Interaction between drug-induced hypersensivity syndrome and viral infections is debated. We report the first case of severe carbamazepine-induced hypersensivity syndrome associated with Epstein-Barr virus infection in a child.
Scagni
Paola
P
Department of Pediatrics, Children's Hospital Regina Margherita, Torino, Italy. scagni@hotmail.com
Morello
Maura
M
Ramus
Marisa Vietti
MV
Agostini
Manuela
M
Pagliero
Rosaura
R
D000927:Anticonvulsants / Q000009:adverse effects*; D002220:Carbamazepine / Q000009:adverse effects*; D002648:Child; D004342:Drug Hypersensitivity / Q000209:etiology*; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D005076:Exanthema / Q000139:chemically induced; D005334:Fever / Q000139:chemically induced; D006529:Hepatomegaly / Q000139:chemically induced; D006801:Humans; D008206:Lymphatic Diseases / Q000139:chemically induced; D008297:Male
D000927:Anticonvulsants; D002220:Carbamazepine