Acute liver failure associated with a prolonged course of acetaminophen at recommended dosages in paediatric age.
Acetaminophen is considered as a safe analgesic and antipyretic drug in paediatric age. The main problem in the use of acetaminophen is acute liver failure after an overdose or an acute intoxication. We report a case of fulminant liver failure and spontaneous recovery in a patient treated with a prolonged course of acetaminophen at recommended dosages.
Gentili
A
A
Department of Paediatric Anaesthesia and Intensive Care, S. Orsola-Malpighi University Hospital, Via Massarenti, 9-40138 Bologna. andrea_gentili@libero.it
Latrofa
M E
ME
Giuntoli
L
L
Melchionda
F
F
Pession
A
A
Lima
M
M
Baroncini
S
S
D000082:Acetaminophen / Q000008:administration & dosage / Q000009:adverse effects*; D000367:Age Factors; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D017114:Liver Failure, Acute / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D009392:Nephrectomy; D011182:Postoperative Care; D013997:Time Factors; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000601:surgery
D000082:Acetaminophen