Kinetic magnetic resonance imaging analysis of abnormal segmental motion of the functional spine unit.
OBJECTIVE
The authors conducted a retrospective observational study using kinetic MR imaging to investigate the relationship between instability, abnormal sagittal segmental motion, and radiographic variables consisting of intervertebral disc degeneration, facet joint osteoarthritis (FJO), degeneration of the interspinous ligaments, ligamentum flavum hypertrophy (LFH), and the status of the paraspinal muscles.


METHODS
Abnormal segmental motion, defined as > 10 degrees angulation and > 3 mm of translation in the sagittal plane, was investigated in 1575 functional spine units (315 patients) in flexion, neutral, and extension postures using kinetic MR imaging. Each segment was assessed based on the extent of disc degeneration (Grades I-V), FJO (Grades 1-4), interspinous ligament degeneration (Grades 1-4), presence of LFH, and paraspinal muscle fatty infiltration observed on kinetic MR imaging. These factors are often noted in patients with degenerative disease, and there are grading systems to describe these changes. For the first time, the authors attempted to address the relationship between these radiographic observations and the effects on the motion and instability of the functional spine unit.


RESULTS
The prevalence of abnormal translational motion was significantly higher in patients with Grade IV degenerative discs and Grade 3 arthritic facet joints (p < 0.05). In patients with advanced disc degeneration and FJO, there was a lesser amount of motion in both segmental translation and angulation when compared with lower grades of degeneration, and this difference was statistically significant for angular motion (p < 0.05). Patients with advanced degenerative Grade 4 facet joint arthritis had a significantly lower percentage of abnormal angular motion compared to patients with normal facet joints (p < 0.001). The presence of LFH was strongly associated with abnormal translational and angular motion. Grade 4 interspinous ligament degeneration and the presence of paraspinal muscle fatty infiltration were both significantly associated with excessive abnormal angular motion (p < 0.05).


CONCLUSIONS
This kinetic MR imaging analysis showed that the lumbar functional unit with more disc degeneration, FJO, and LFH had abnormal sagittal plane translation and angulation. These findings suggest that abnormal segmental motion noted on kinetic MR images is closely associated with disc degeneration, FJO, and the pathological characteristics of interspinous ligaments, ligamentum flavum, and paraspinal muscles. Kinetic MR imaging in patients with mechanical back pain may prove a valuable source of information about the stability of the functional spine unit by measuring abnormal segmental motion and grading of radiographic parameters simultaneously.
Kong
Min Ho
MH
Department of Orthopaedic Surgery, University of California at Los Angeles, California, USA.
Hymanson
Henry J
HJ
Song
Kwan Young
KY
Chin
Dong Kyu
DK
Cho
Yong Eun
YE
Yoon
Do Heum
DH
Wang
Jeffrey C
JC
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007405:Intervertebral Disc Displacement / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D007593:Joint Instability / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D017843:Ligamentum Flavum / Q000473:pathology; D008159:Lumbar Vertebrae / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D015588:Observer Variation; D055013:Osteoarthritis, Spine / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D015995:Prevalence; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult