Comparative study of retinal nerve fiber layer thickness in normal eyes, ocular hypertensives, preperimetric glaucoma and glaucomatous subjects.
We assessed and compared the retinal nerve fiber layer (RNFL) thickness in normal eyes, ocular hypertensives, preperimetric glaucoma and glaucomatous subjects by means of optical coherence tomography in 449 eye. RNFL in glaucoma patients was significantly thinner than in normal subjects in every location evaluated. Use of optical coherence tomography detects glaucomatous RNFL losses in preperimetric glaucoma and can improve our ability to detect structural damage in clinical practice.
Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain. vicpolo@telefonica.net
Vicente
V
Polo
Jose M
JM
Larrosa
Antonio
A
Ferreras
Jose M Martinez
JM
de la Casa
Luis E
LE
Pablo
Francisco M
FM
Honrubia
D019540:Area Under Curve; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009798:Ocular Hypertension / Q000175:diagnosis; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012016:Reference Values; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*; D014065:Tonometry, Ocular; D014794:Visual Fields