Cutaneous skull metastasis from uterine leiomyosarcoma: a case report.
BACKGROUND
Cutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer.


METHODS
A 52-year-old woman who admitted with a lung and a skull skin nodule is presented. She had a known diagnosis of uterine leiomyosarcoma following an extended total hysterectomy two years ago. Excision biopsy of both nodules revealed metastatic disease.


CONCLUSIONS
The appearance of a cutaneous nodule in a patient with a history of uterine leiomyosarcoma might indicate a metastatic tumor lesion. Biopsy and immunohistochemistry are essential for correct diagnosis.
Thoracic Surgery Department, Theagenio Cancer Hospital, A. Simeonidi 2, Thessaloniki, 54007, Greece. nibarbet@yahoo.gr
Nikolaos
N
Barbetakis
Dimitrios
D
Paliouras
Christos
C
Asteriou
Georgios
G
Samanidis
Athanassios
A
Kleontas
Doxakis
D
Anestakis
Kostas
K
Kaplanis
Christodoulos
C
Tsilikas
D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary*; D012886:Skull / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery