Analysis of bispectral index and middle latency auditory-evoked potentials parameters in critically ill children.
To study the parameters of the bispectral index and middle latency auditory-evoked potentials in critically ill children. We performed a prospective, observational study in 81 critically ill children categorized into two levels of sedation (moderate and deep) and three age groups (<1, 1-6, and >6 months). The parameters of the bispectral index and middle latency auditory-evoked potentials studied were the signal quality index, suppression ratio, total power, spectral edge frequency, electromyographic activity, and suppression ratio. Suppression rates were higher in children younger than 1 month than in older children and were also higher in deep sedation. Total power and spectral edge frequency increased with age. Electromyographic activity was higher in moderate sedation. Spectral edge frequency and suppression rates change with age and level of sedation. These variations are a consequence of the electroencephalographic structure at young ages and are secondary to the higher proportion of slow waves in deep states of sedation.
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Adelaida
A
Lamas
Jesús
J
López-Herce
Luis
L
Sancho
Santiago
S
Mencía
Angel
A
Carrillo
Maria José
MJ
Santiago
Vicente
V
Martínez
D000293:Adolescent; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D016638:Critical Illness / Q000145:classification*; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011930:Reaction Time / Q000187:drug effects*
D006993:Hypnotics and Sedatives