Australia's national Q fever vaccination program.
A nationally funded Q fever vaccination program was introduced in Australia in 2002. The evaluation of this unique program included measures of program uptake, safety, and notification and hospitalisation rates for Q fever pre- and post-program implementation. Program uptake ranged from close to 100% amongst abattoir workers to 43% in farmers. The most commonly reported adverse event was injection site reaction. Q fever notification rates declined by over 50% between 2002 and 2006, particularly in young adult males, consistent with the profile of the abattoir workforce. Hospitalisation data showed similar trends. Available evidence suggests a significant impact of Australia's Q fever vaccination program; such a program merits consideration in other countries with a comparable Q fever disease burden.
Gidding
Heather F
HF
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Darlinghurst, New South Wales 2010, Australia. hgidding@nchecr.unsw.edu.au
Wallace
Cate
C
Lawrence
Glenda L
GL
McIntyre
Peter B
PB
D000293:Adolescent; D000328:Adult; D000368:Aged; D001315:Australia / Q000453:epidemiology; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D016997:Coxiella burnetii / Q000276:immunology*; D005076:Exanthema / Q000209:etiology; D005260:Female; D006078:Government Programs / Q000191:economics / Q000639:trends*; D006801:Humans; D017589:Immunization Programs / Q000639:trends*; D015994:Incidence; D007223:Infant; D007267:Injections; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D011778:Q Fever / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control*; D014611:Vaccination
D001428:Bacterial Vaccines