Counterion effects in a gold-catalyzed synthesis of pyrroles from alkynyl aziridines.
Aryl-substituted N-tosyl alkynyl aziridines undergo a gold-catalyzed ring expansion to afford 2,5-substituted pyrrole products. Under certain conditions, a ring-expansion and rearrangement leads to 2,4-substituted pyrroles. The reaction pathway is determined by the counterion to the gold catalyst.
Davies
Paul W
PW
School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. p.w.davies@bham.ac.uk
Martin
Nicolas
N