Pharmacological approaches to modifying HDL: more basic science to understand HDL metabolism is necessary. Editorial to: "NO-1886 up-regulates Niemann-Pick C1 protein (NPC1) expression through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells" by Xin Ma et al.
Michael H
MH
Davidson
D050197:Atherosclerosis / Q000378:metabolism*; D001549:Benzamides / Q000494:pharmacology*; D002352:Carrier Proteins / Q000096:biosynthesis*; D008076:Cholesterol, HDL / Q000097:blood / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000502:physiology*; D005487:Foam Cells / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D047908:Intracellular Signaling Peptides and Proteins; D000071518:Liver X Receptors; D008562:Membrane Glycoproteins / Q000096:biosynthesis*; D000077296:Niemann-Pick C1 Protein; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D057093:Orphan Nuclear Receptors; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology*; D015854:Up-Regulation
D001549:Benzamides; D002352:Carrier Proteins; D008076:Cholesterol, HDL; D004268:DNA-Binding Proteins; D000960:Hypolipidemic Agents; D047908:Intracellular Signaling Peptides and Proteins; D000071518:Liver X Receptors; D008562:Membrane Glycoproteins; C106881:NPC1 protein, human; C000605213:NR1H3 protein, human; D000077296:Niemann-Pick C1 Protein; D009943:Organophosphorus Compounds; D057093:Orphan Nuclear Receptors; D018160:Receptors, Cytoplasmic and Nuclear; C082137:4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide