Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine.
Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.
Pirola
Elena
E
Neurosurgery, University of Milano-Bicocca, Monza, Italy. oxosintesi@libero.it
Vergani
Francesco
F
Casiraghi
Paolo
P
Leone
Eugenio Biagio
EB
Guerra
Paolo
P
Sganzerla
Erik Pietro
EP
D006801:Humans; D007015:Hypophosphatemia, Familial / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008637:Mesenchymoma / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D010018:Osteomalacia / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000209:etiology; D013123:Spinal Fusion; D013125:Spinal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000601:surgery