Genomic and biochemical analysis of N glycosylation in the mushroom-forming basidiomycete Schizophyllum commune.
N-linked glycans of Schizophyllum commune consist of Man(5-9)GlcNAc(2) structures. Lack of further glycan maturation is explained by the absence of genes encoding such functions in this and other homobasidiomycetes. N-linked glycans in vegetative mycelium and fruiting bodies of S. commune are mainly Man(7)GlcNAc(2) and Man(5)GlcNAc(2), respectively, suggesting more efficient mannose trimming in the mushroom.
Berends
Elsa
E
Molecular Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Institute of Biomembranes, Utrecht University, The Netherlands. E.Berends@uu.nl
Ohm
Robin A
RA
de Jong
Jan F
JF
Rouwendal
Gerard
G
Wösten
Han A B
HA
Lugones
Luis G
LG
Bosch
Dirk
D
D005800:Genes, Fungal; D006031:Glycosylation; D006801:Humans; D008358:Mannose / Q000378:metabolism; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism; D012567:Schizophyllum / Q000235:genetics / Q000378:metabolism*
D009584:Nitrogen; D008358:Mannose