Involvement of two transport systems and a specific porin in the uptake of phthalate by Burkholderia spp.
Burkholderia spp. that degrade phthalate have an ABC transporter-type phthalate transport system (OphFGH) and a specific porin (OphP) in addition to a permease-type phthalate transporter (OphD). OphFGH has a lower K(m) and higher V(max) than OphD, which affects how the bacteria grow. OphP is involved in both mechanisms of transport.
Biotechnology Center for Agriculture and the Environment, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ 08901-8520, USA. hkchang@rci.rutgers.edu
Hung-Kuang
HK
Chang
Jonathan J
JJ
Dennis
Gerben J
GJ
Zylstra
D000963:Antimetabolites / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D019117:Burkholderia / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D003001:Cloning, Molecular; D055786:Gene Knockout Techniques; D023061:Gene Order; D007700:Kinetics; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D009876:Operon; D027361:Organic Anion Transporters / Q000378:metabolism; D010795:Phthalic Acids / Q000378:metabolism*; D018272:Porins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism
D000963:Antimetabolites; D001426:Bacterial Proteins; D026901:Membrane Transport Proteins; D027361:Organic Anion Transporters; D010795:Phthalic Acids; D018272:Porins; C121797:ophD protein, Burkholderia cepacia; C032279:phthalic acid