FlexServ: an integrated tool for the analysis of protein flexibility.
CONCLUSIONS
FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemann's indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics.


BACKGROUND
http://mmb.pcb.ub.es/FlexServ; http://www.inab.org
Camps
Jordi
J
Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona, Spain.
Carrillo
Oliver
O
Emperador
Agustí
A
Orellana
Laura
L
Hospital
Adam
A
Rueda
Manuel
M
Cicin-Sain
Damjan
D
D'Abramo
Marco
M
Gelpí
Josep Lluís
JL
Orozco
Modesto
M
D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D020407:Internet; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D020539:Sequence Analysis, Protein; D012984:Software
D011506:Proteins