Synthesis and insecticidal activity of new 4-hydroxy-2H-1-benzopyran-2-one derivatives.
Several stable and storable anticoagulant rodenticides involving both merits of acute and chronic rodenticides have been synthesized (Holbrook et al. in Arch Intern Med 165:1095-1106, 2005; Baglin et al. in Br J Haematol 132:277-285, 2006). The structures of synthesized compounds were confirmed by IR, (1)H NMR. The compounds were also evaluated for their anticoagulant and acute biologic activity (Lipton et al., JAMA 252:3004-3005, 3).
Wang
Meijing
M
Department of Chemistry, Northeastern University, Shenyang City, People's Republic of China. meijingnancy@hotmail.com
Chen
Feng
F
Guan
Jian
J
Zhao
Jing
J
Zhang
Jiufu
J
Zhao
Renhe
R
D000818:Animals; D000925:Anticoagulants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005260:Female; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D015394:Molecular Structure; D012378:Rodenticides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000925:Anticoagulants; D007306:Insecticides; D012378:Rodenticides