Foaling rates and risk factors for abortion in pregnant mares presented for medical or surgical treatment of colic: 153 cases (1993-2005).
The purpose of this study was to determine foaling rates in mares presented for medical or surgical treatment of colic, and to examine risk factors associated with abortion following colic. A retrospective analysis of 153 medical records found that mares treated surgically for colic (P = 0.0007) were 3.5 times more likely to have a negative pregnancy outcome than were mares treated medically for colic. Anesthetic time (P = 0.01) and intra-operative hypotension (P = 0.03) were significantly associated with negative pregnancy outcome. Mares with an anesthetic time > or = 3 h were 6 times more likely to abort. Signs of endotoxemia (P = 0.30), hypoxia (P = 0.89), flunixin meglumine administration (P = 0.13), mucous membrane color at the time of presentation (P = 0.82) and capillary refill time (P = 0.76) were not associated with pregnancy outcome. There was no difference in the foaling rate for mares that had received progestin supplementation versus those that had not (P = 0.42). In this study, the significant risk factors for abortion were surgically treated colic, long anesthetic time, and intraoperative hypotension.
Chenier
Tracey S
TS
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1. tchenier@uoguelph.ca
Whitehead
Ashley E
AE
D000034:Abortion, Veterinary / Q000453:epidemiology / Q000209:etiology; D000758:Anesthesia / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D003085:Colic / Q000503:physiopathology / Q000601:surgery / Q000628:therapy / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D006736:Horses; D007022:Hypotension / Q000503:physiopathology / Q000662:veterinary*; D000860:Hypoxia / Q000503:physiopathology / Q000662:veterinary; D007431:Intraoperative Complications / Q000662:veterinary; D011247:Pregnancy; D011248:Pregnancy Complications / Q000662:veterinary*; D011256:Pregnancy Outcome / Q000662:veterinary; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome