Soft tissue augmentation with ArteFill.
ArteFill is a novel, third-generation polymethylmethacrylate (PMMA) injectable filler with unique properties. When compared with predecessor materials, ArteFill demonstrates improved biocompatibility as a result of more uniform PMMA microsphere size and shape. This translates into less adverse events after placement. ArteFill can provide a permanent volume enhancement by stimulation of fibroblasts that encapsulate nonabsorbable microspheres with collagen deposition. Currently, ArteFill is FDA approved for permanent augmentation of moderately deep nasolabial folds. It is also commonly used off-label for augmentation of other skin creases and regional areas of volume deficiency, such as the tear trough-malar and marionette line-prejowl sulcus regions. The key to success with ArteFill is a conservative approach with avoidance of overcorrection. Proper technique includes deep dermal to subcutaneous placement with full correction achieved gradually over several treatments. Complications are mostly limited to nodule formation, which is easily managed in most cases with conservative intervention.
Hilinski
John M
JM
San Diego Face and Neck Specialties, San Diego, California 92103, USA. info@drhilinski.com
Cohen
Steven R
SR
D000818:Animals; D001672:Biocompatible Materials / Q000008:administration & dosage*; D002417:Cattle; D020219:Chondrogenesis / Q000187:drug effects; D003094:Collagen / Q000008:administration & dosage*; D003357:Cosmetic Techniques; D005145:Face; D006801:Humans; D007279:Injections, Subcutaneous / Q000379:methods; D008863:Microspheres; D009666:Nose; D009667:Nose Deformities, Acquired / Q000188:drug therapy; D018579:Patient Selection; D019904:Polymethyl Methacrylate / Q000008:administration & dosage*; D012060:Rejuvenation; D015595:Skin Aging
C516180:ArteFill; D001672:Biocompatible Materials; D003094:Collagen; D019904:Polymethyl Methacrylate