PIDA-mediated oxidative C-C bond formation: novel synthesis of indoles from N-aryl enamines.
A variety of functionalized indoles were synthesized from N-aryl enamines via PIDA-mediated oxidative carbon-carbon bond formation. The features of the present reaction include facilitative preparation of substrates 2, good functional group tolerance, and mild reaction conditions without transition metals.
Yu
Wenquan
W
Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Du
Yunfei
Y
Zhao
Kang
K
D000085:Acetates / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000085:Acetates; D000588:Amines; D001555:Benzene Derivatives; D007211:Indoles; D007462:Iodobenzenes