Atomoxetine Treatment for Cocaine Abuse and Adult Attention-Deficit Hyperactivity Disorder (ADHD): A Preliminary Open Trial.
The purpose of this 12-week open trial was to evaluate the potential utility of atomoxetine for the treatment of attention deficit hyperactivity disorder (ADHD) in cocaine-dependent treatment seekers. The sample consisted of 20 participants with all participants meeting DSM-IV-TR criteria for ADHD and cocaine dependence (CD). Using several measures to assess ADHD, there was a significant reduction in ADHD symptoms. There was no significant decrease in cocaine use throughout the trial. Taken together, although cocaine-dependent individuals showed some reduction in ADHD symptoms while receiving atomoxetine, the high drop-out rate and lack of impact on cocaine use may limit its utility in ADHD adults who are currently abusing cocaine.
New York State Psychiatric Institute, Division on Substance Abuse 1051 Riverside Drive New York, NY 10032 USA.
Frances R
FR
Levin
John J
JJ
Mariani
Alex
A
Secora
Daniel
D
Brooks
Wendy Y
WY
Cheng
Adam
A
Bisaga
Edward
E
Nunes
Efrat
E
Aharonovich
Wilfrid
W
Raby
Grace
G
Hennessy