On catalysis by ionic liquids.
A molecular level mechanism of catalysis by an ionic liquid (IL) is proposed as an "electrophile nucleophile dual activation" through a "relay of cooperative hydrogen bonds and charge-charge interactions". Spectroscopic ((1)H NMR and IR) studies were used to probe the involvement of the C-2 hydrogen and the AcO(-) anion of [bmim][OAc] in the catalysis for O-t-Boc formation. Ion fishing by MALDI-TOF-TOF MS and MS-MS established the hydrogen bonded clusters.
Chakraborti
Asit K
AK
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar 160 062, Punjab, India. akchakraborti@niper.ac.in
Roy
Sudipta Raha
SR
D000085:Acetates / Q000737:chemistry; D001881:Borates / Q000737:chemistry; D002384:Catalysis; D002412:Cations; D007093:Imidazoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013055:Spectrophotometry, Infrared
C525963:1-butyl-3-methylimidazolium; D000085:Acetates; D001881:Borates; D002412:Cations; D007093:Imidazoles