[Quantitated thyroid scan (123I) of the thyroid nodule: a new molecular imaging].
Thyroid nodules are a common clinical finding which often indicates, aside from cancer, a more diffuse disease, such as multinodular goiter, auto-immune thyroid disease or thyroid autonomy. Recent reports suggest that the overall prognosis of thyroid autonomy compares with that of pT2/pT3 thyroid cancer, even in patients with low to normal TSH levels. The thyroid scan (I123) can be quantified, thus offering a powerful tool to diagnose thyroid hyperfunction when local uptake measurements appear innappropriately high as regards to TSH levels. Finally, correlation with ultrasound reduces the number of FNA to suspicious nodules only and optimizes follow-up and specific treatment (lT4, I131) of most benign nodular thyroid diseases.
Université Paris Descartes, Service de Médecine Nucléaire, Hôpital Cochin, 27 rue du Faubourg Saint Jacques, 75679 Paris cedex 14, France. jerome.clerc@cch.aphp.fr
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D000328:Adult; D001345:Autoradiography; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D006044:Goiter, Nodular / Q000000981:diagnostic imaging*; D006801:Humans; D006980:Hyperthyroidism / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011877:Radionuclide Imaging / Q000379:methods*; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging*; D013972:Thyrotropin / Q000097:blood; D013997:Time Factors; D018608:Ultrasonography, Doppler
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D019788:Fluorodeoxyglucose F18; D013972:Thyrotropin; D017256:Technetium Tc 99m Sestamibi