[Ketorolac as a possible cause of reversible renal dysfunction in a 5-year-old child].
This case report describes postoperative, reversible renal dysfunction and hypertension in a 5-year-old healthy boy after administration of relevant doses of ketorolac during anaesthesia. Two days postoperatively, the boy presented with polyuria, polydipsia, proteinuria, microscopic haematuria, and hypertension. He was treated with nifedipine. After six months the blood pressure and azotaemia parameters had normalised and antihypertensive treatment was discontinued.
Rigshospitalet, Juliane Marie Centret, Anaestesi- og operationsklinikken.
Søren Mehl
SM
Knudsen
Teit
T
Mantoni
Søren
S
Walther-Larsen
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D006554:Hernia, Umbilical / Q000601:surgery; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D020910:Ketorolac / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D010149:Postoperative Pain / Q000517:prevention & control; D011183:Postoperative Complications / Q000139:chemically induced; D051437:Renal Insufficiency / Q000139:chemically induced*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D020910:Ketorolac