Reversible posterior encephalopathy syndrome associated with micronodular adrenocortical disease and Cushing syndrome.
We report a 6-year-old girl with ACTH-independent Cushing syndrome secondary to bilateral adrenal hyperplasia; she presented with hypertension and seizures, and magnetic resonance imaging shows changes consistent with posterior reversible encephalopathy syndrome.
Section on Endocrinology & Genetics (SEGEN) & Pediatric Endocrinology Program, Program on Developmental Endocrinology & Genetics (PDEGEN), National Institute of Child Health and Human Development (NICHD), Building 10 (CRC-East), Room 1-3330, 10 Center Dr. MSC 1103, Bethesda, MD 20892, USA. lodishma@mail.nih.gov
Maya
M
Lodish
Nicholas J
NJ
Patronas
Constantine A
CA
Stratakis
D000312:Adrenal Hyperplasia, Congenital / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000315:Adrenalectomy; D001794:Blood Pressure / Q000502:physiology; D002648:Child; D003480:Cushing Syndrome / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D054038:Posterior Leukoencephalopathy Syndrome / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed