Primary testicular presentation of ALK-1-negative anaplastic large cell lymphoma in a pediatric patient.
Anaplastic large cell lymphoma is a heterogeneous group of malignant non-Hodgkin lymphomas that occurs in up to 15% of all pediatric non-Hodgkin lymphomas. It is characterized by B-symptoms and involvement of extranodal sites such as skin, bone, and soft tissue. This brief report describes first reported case of pediatric primary testicular anaplastic large cell lymphoma in a 14-year-old boy. The presentation included acute testicular pain, fever, and vomiting. After chemotherapy and unilateral radical orchiectomy, patient continues in complete remission.
Lagmay
Joanne
J
Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.
Termuhlen
Amanda
A
Fung
Bonita
B
Ranalli
Mark
M
D030301:Activin Receptors, Type II / Q000378:metabolism*; D000293:Adolescent; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D002467:Cell Nucleus / Q000378:metabolism / Q000473:pathology; D006056:Golgi Apparatus / Q000378:metabolism / Q000473:pathology; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery; D008297:Male; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery; D013737:Testis / Q000473:pathology / Q000601:surgery
D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen; C425364:ACVRL1 protein, human; D030301:Activin Receptors, Type II