title: OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells.
authors.affiliation: Hubrecht Institute, KNAW & University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Laurens G
authors.initials: LG
authors.lastname: van der Flier
authors.forename: Andrea
authors.initials: A
authors.lastname: Haegebarth
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Stange
authors.forename: Marc
authors.initials: M
authors.lastname: van de Wetering
authors.forename: Hans
authors.initials: H
authors.lastname: Clevers
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology; D014408:Biomarkers, Tumor / Q000378:metabolism*; D015179:Colorectal Neoplasms / Q000378:metabolism* / Q000473:pathology; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism*; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000378:metabolism* / Q000473:pathology; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D013234:Stem Cells / Q000378:metabolism* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; C116884:LGR5 protein, human; C454127:OLFM4 protein, human; D043562:Receptors, G-Protein-Coupled; D016179:Granulocyte Colony-Stimulating Factor