title: Diterpenoids from Casearia sylvestris.
abstract: Two highly oxygenated clerodane diterpenes casearins U (1) and V (2) and two ent-kaurane diterpene glucosides sylvestrisides A (3) and B (4) were isolated from the leaves of Casearia sylvestris, together with 13 known compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic analyses and comparison with literature data.
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, MS 38677, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Jianpin
authors.initials: J
authors.lastname: Zhao
authors.forename: Yan-hong
authors.initials: YH
authors.lastname: Wang
authors.forename: Troy A
authors.initials: TA
authors.lastname: Smillie
authors.forename: Xing-Cong
authors.initials: XC
authors.lastname: Li
authors.forename: Ikhlas A
authors.initials: IA
authors.lastname: Khan
mesh_terms: D000818:Animals; D037821:Casearia / Q000737:chemistry*; D045744:Cell Line, Tumor; D002522:Chlorocebus aethiops; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves; D014709:Vero Cells
chemical_list: D004224:Diterpenes; D005960:Glucosides; D010936:Plant Extracts; C547860:casearin U; C547861:casearin V; C547863:sylvestriside A; C547862:sylvestriside B