title: Narrowing the window for 'senile chorea': a case with primary antiphospholipid syndrome.
abstract: Several apparently idiopathic cases of so called 'senile chorea' have been recently redefined by the availability of brain MRI scan and the clinical introduction of genetic testing for Huntington's disease. Cases currently still regarded as idiopathic might yet be attributed to other medical conditions. Chorea as a unique manifestation of a primary antiphospholipid syndrome (PAPS) has so far been described only in young and middle-aged subjects. Here, we report a typical case of 'senile chorea' associated with PAPS, thus expanding the potential underlying etiologies and further narrowing the window of primary 'senile chorea'.
authors.affiliation: Dept. of Neurology, San Gerardo Hospital, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Gelosa
authors.forename: L
authors.initials: L
authors.lastname: Tremolizzo
authors.forename: A
authors.initials: A
authors.lastname: Galbussera
authors.forename: R
authors.initials: R
authors.lastname: Perego
authors.forename: M
authors.initials: M
authors.lastname: Capra
authors.forename: M
authors.initials: M
authors.lastname: Frigo
authors.forename: P
authors.initials: P
authors.lastname: Apale
authors.forename: C
authors.initials: C
authors.lastname: Ferrarese
authors.forename: I
authors.initials: I
authors.lastname: Appollonio
mesh_terms: D017668:Age of Onset; D000368:Aged; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use; D017152:Antibodies, Antiphospholipid / Q000097:blood; D000927:Anticonvulsants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D001479:Basal Ganglia / Q000473:pathology; D002220:Carbamazepine / Q000031:analogs & derivatives / Q000627:therapeutic use; D002819:Chorea / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D003975:Diazepam / Q000627:therapeutic use; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D000078330:Oxcarbazepine
chemical_list: D018726:Anti-Dyskinesia Agents; D017152:Antibodies, Antiphospholipid; D000927:Anticonvulsants; D002220:Carbamazepine; D006220:Haloperidol; D003975:Diazepam; D000078330:Oxcarbazepine