Modularity, comparative embryology and evo-devo: developmental dissection of evolving body plans.
Modules can be defined as quasi-autonomous units that are connected loosely with each other within a system. A need for the concept of modularity has emerged as we deal with evolving organisms in evolutionary developmental research, especially because it is unknown how genes are associated with anatomical patterns. One of the strategies to link genotypes with phenotypes could be to relate developmental modules with morphological ones. To do this, it is fundamental to grasp the context in which certain anatomical units and developmental processes are associated with each other specifically. By identifying morphological modularities as units recognized by some categories of general homology as established by comparative anatomy, it becomes possible to identify developmental modules whose genetic components exhibit coextensive expressions. This permits us to distinguish the evolutionary modification in which the identical morphological module simply alters its shape for adaptation, without being decoupled from the functioning gene network ('coupled modularities'), from the evolution of novelty that involves a heterotopic shift between the anatomical and developmental modules. Using this formulation, it becomes possible, within the realm of Geoffroy's homologous networks, to reduce morphological homologies to developmental mechanistic terms by dissociating certain classes of modules that are often associated with actual shapes and functions.
Kuratani
Shigeru
S
Evolutionary Morphology Research Group, RIKEN Center for Developmental Biology, 2-2-3 Minatojima Minamimachi, Kobe 650-0047, Japan. saizo@cdb.riken.jp
D000818:Animals; D005075:Biological Evolution; D004626:Embryology; D048788:Growth and Development; D007568:Jaw / Q000033:anatomy & histology; D007798:Lampreys / Q000033:anatomy & histology