[Choroidal metastasis from a breast carcinoma. Diagnosis and follow-up with optical coherence tomography and fluorescein angiography and autofluorescence with HRA-II (Heidelberg Retina Angiograph)].
METHODS
A 69-year-old woman developed choroidal metastasis from a breast carcinoma 2 years after the initial diagnosis, surgery and chemotherapy. After treatment with palliative chemotherapy and external radiotherapy, we used fluorescein angiography (FA) and optical coherence tomography (OCT) to evaluate the resolution of the serous retinal detachment, as well as a later relapse in the optic nerve.


CONCLUSIONS
OCT is useful in the follow-up of choroidal metastasis after treatment. However, OCT imaging is limited by the initial choroidal location of metastasis. The autofluorescence can detect exudative tumoral activity even without obvious changes in OCT or FA.
Pérez-Alvarez
M J
MJ
Hospital Clínico San Carlos, Unidad de Retina, Madrid, Spain. mjperezalv@hotmail.com
Arriola-Villalobos
P
P
Reche-Frutos
J
J
García-Sánchez
J
J
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D002830:Choroid Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000031:analogs & derivatives; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005451:Fluorescein Angiography; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008197:Lymph Node Excision; D015409:Mastectomy, Radical; D019574:Optic Nerve Neoplasms / Q000556:secondary; D010166:Palliative Care; D012163:Retinal Detachment / Q000209:etiology; D041623:Tomography, Optical Coherence
D004317:Doxorubicin; D003520:Cyclophosphamide; C003726:trofosfamide; D005472:Fluorouracil