Non-surgical management of hormone-secreting pituitary tumors.
Hormone-secreting pituitary tumors account for about 30% of all pituitary tumors. Successful long-term management of patients with these tumors frequently requires a multimodality team approach. Given that the role and efficacy of neurosurgical resection of hormone-secreting pituitary tumors is well described, we focus this review on the other important treatment modalities that are becoming increasingly crucial in the management of acromegaly, Cushing's disease and prolactinomas. Medical management with standard and novel drugs as well as the role and effectiveness of radiation therapy and radiosurgery are discussed in detail.
Patil
Chirag G
CG
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA. chiragpatil@gmail.com
Hayden
Melanie
M
Katznelson
Laurence
L
Chang
Steven D
SD
D000172:Acromegaly / Q000628:therapy*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D047748:Pituitary ACTH Hypersecretion / Q000628:therapy*; D010911:Pituitary Neoplasms / Q000378:metabolism / Q000628:therapy*; D015175:Prolactinoma / Q000378:metabolism / Q000628:therapy*; D016634:Radiosurgery / Q000009:adverse effects; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage
D000970:Antineoplastic Agents; D006728:Hormones