Adsorption and adhesion of blood proteins and fibroblasts on multi-wall carbon nanotubes.
This article concerns the investigation of blood protein adsorption on carbon paper and multi-wall carbon nanotubes (MWCNTs). Mouse fibroblast cell adhesion and growth on MWCNTs was also studied. The results showed that fibrinogen adsorption on carbon paper was much lower than that on MWCNTs, which means that platelets readily aggregate on the surface of MWCNTs. Mouse fibroblast cells implanted on MWCNTs tended to grow more prolifically than those implanted on carbon paper. The cell concentration observed on MWCNTs increased from 1.2x10(5)/mL for a single day culture to 2x10(5)/mL for a 7-day culture. No toxicity reaction was observed during the culturing period. These results indicated that MWCNTs possessed excellent tissue compatibility.
Li
Dejun
D
College of Physics and Electronic Information Science, Tianjin Normal University, Tianjin, 300074, China. dejunli@mail.tjnu.edu.cn
Yuan
Li
L
Yang
Ying
Y
Deng
Xiangyun
X
Lü
Xiaoying
X
Huang
Yan
Y
Cao
Zheng
Z
Liu
Hao
H
Sun
Xueliang
X
D000327:Adsorption; D000818:Animals; D001798:Blood Proteins / Q000737:chemistry* / Q000378:metabolism; D002244:Carbon / Q000737:chemistry; D002448:Cell Adhesion; D049109:Cell Proliferation; D005340:Fibrinogen / Q000737:chemistry / Q000378:metabolism; D005347:Fibroblasts / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D051379:Mice; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010209:Paper; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties
D001798:Blood Proteins; D037742:Nanotubes, Carbon; D002244:Carbon; D005340:Fibrinogen