Flexible synthesis of fused benzofuran derivatives by rhodium-catalyzed [2 + 2 + 2] cycloaddition with phenol-linked 1,6-diynes.
A flexible and convenient synthesis of fused benzofuran derivatives has been achieved under mild reaction conditions by cationic rhodium(I)/H(8)-BINAP complex-catalyzed [2 + 2 + 2] cycloadditions of phenol-linked 1,6-diynes with alkynes and nitriles.
Komine
Yoshiyuki
Y
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan.
Kamisawa
Akiyoshi
A
Tanaka
Ken
K
D000480:Alkynes / Q000737:chemistry*; D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
D000480:Alkynes; D001572:Benzofurans; D006575:Heterocyclic Compounds, 3-Ring; D010636:Phenols; D012238:Rhodium