Cerebellar hemorrhage in a patient with propionic acidemia.
Cerebellar hemorrhage (CH) is a well-known complication in newborns. Among metabolic patients, it has been classically described but rarely reported. This is the first description of a patient with propionic acidemia in whom magnetic resonance imaging (MRI) allowed diagnosis of asymptomatic CH. Due to the usual silent presentation of CH at early ages, we suggest the possibility of including a brain MRI study as part of the routine neurological evaluation in metabolic patients, especially when neurological signs appear.
Velasco-Sánchez
Daniel
D
Neurology and Metabolism Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues de Llobregat, Barcelona, Spain. dvelasco@hsjdbcn.org
Gómez-Lopez
Lilianne
L
Vilaseca
María Antonia
MA
Serrano
Mercedes
M
Massaguer
Sara
S
Campistol
Jaume
J
García-Cazorla
Angels
A
D000592:Amino Acid Metabolism, Inborn Errors / Q000150:complications* / Q000378:metabolism* / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D011422:Propionates / Q000378:metabolism*
D011422:Propionates