title: Could it be Henoch-Schonlein purpura?
abstract: BACKGROUND
  Henoch-Schönlein purpura is the most common form of systemic vasculitis in the paediatric setting with 90% of cases occuring in childhood. Although diagnosis in the primary care setting may be difficult, it is vital in order to avoid significant complications.
  
  
  OBJECTIVE
  This article outlines the pathogenesis, clinical manifestations and classification of Henoch-Schönlein purpura and details evidence based investigations and management.
  
  
  CONCLUSIONS
  Henoch-Schönlein purpura is a self limiting disease characterised by a tetrad of clinical manifestations that vary in occurrence and order of presentation. There is no single diagnostic test to confirm Henoch- Schönlein purpura; diagnosis depends on recognition of clinical manifestations. Management usually occurs in the ambulatory setting and is mainly supportive. Priorities include symptom relief and preventive therapy to reduce the risk of complications. Further trials to clarify the role of glucocorticosteroids are needed before a definitive role for steroids in the management of Henoch-Schönlein purpura can be established.
authors.affiliation: Integrative Medicine Research, School of Medicine, Sydney, University of Notre Dame Australia. celim@unswalumni.com
authors.forename: Danforn C E
authors.initials: DC
authors.lastname: Lim
authors.forename: Lisa N C
authors.initials: LN
authors.lastname: Cheng
authors.forename: Felix W S
authors.initials: FW
authors.lastname: Wong
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011695:IgA Vasculitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D012867:Skin / Q000276:immunology / Q000473:pathology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D007070:Immunoglobulin A