title: Complexability of o-bisguanidinobenzenes with arsenic and phosphoric acids in solution and solid states, and the potential use of their immobilized derivatives as solid base ligands for metal salts and arsenic acid.
abstract: The role of o-bisguanidinobenzenes (BGBs) as new Brønsted base ligands for arsenic and phosphoric acids was examined. In solution state, complexation was evaluated by Job's plot in (1)H NMR experiment, indicating a 1:1 complex formation, whereas in solid state crystalline structures of complexes obtained were addressed by X-ray crystallographic analysis and/or solid state (13)C NMR experiment, in which 1:2 complexes between the BGB and the acid components were normally formed. Based on these results, Merrifield and Hypogel resin-anchored BGBs were designed and prepared as the corresponding polymer-supported host ligands. Evaluation of their coordination ability with metal salts (ZnCl(2) and CoCl(2)) and arsenic acid in aqueous media by ICP-MS showed that the latter Hypogel resin-anchored BGBs acted as effective immobilized base ligands.
authors.affiliation: Department of Medicinal Organic Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba, 263-8522, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Ito
authors.forename: Koji
authors.initials: K
authors.lastname: Suda
authors.forename: Takuya
authors.initials: T
authors.lastname: Kumamoto
authors.forename: Waka
authors.initials: W
authors.lastname: Nakanishi
authors.forename: Toshiko
authors.initials: T
authors.lastname: Watanabe
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Hiroko
authors.initials: H
authors.lastname: Seki
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kawahata
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Yasumitsu
authors.initials: Y
authors.lastname: Ogura
authors.forename: Kazuo T
authors.initials: KT
authors.lastname: Suzuki
mesh_terms: D001149:Arsenates / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis / Q000737:chemistry*; D002247:Carbon Isotopes; D018360:Crystallography, X-Ray; D006146:Guanidines / Q000138:chemical synthesis / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000737:chemistry; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D010756:Phosphoric Acids / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D044366:Transition Temperature; D014874:Water Pollutants, Chemical; D018508:Water Purification
chemical_list: D001149:Arsenates; D001555:Benzene Derivatives; D002247:Carbon Isotopes; D006146:Guanidines; D008024:Ligands; D008670:Metals; D010756:Phosphoric Acids; D012492:Salts; D014874:Water Pollutants, Chemical; C025657:arsenic acid