title: Testis-sparing surgery for benign and malignant tumors: A critical analysis of the literature.
abstract: In order to explore the latest advances in organ-sparing treatment of testicular tumors, a literature search of the Medline/PubMed database was carried out for published data in the English language up to 2007.In the recent past the management of testicular tumors has evolved in favor of a testis-sparing approach in selected cases, both in the adult and pediatric population. The widespread use of high-frequency testicular ultrasound has led to detecting an increasing number of asymptomatic, non-palpable, small-volume masses. A higher proportion of testicular lesions of benign nature than previously reported has now been documented. The high accuracy of frozen section examination and the increasing interest in the potential functional, psychological and cosmetic advantages related to preserved testicular parenchyma are other arguments currently favoring the adoption of an organ-sparing policy for most testicular masses. Greater experience has been gained in also managing conservatively malignant tumors. Patients with germ-cell cancer in solitary testis or bilateral tumors can be submitted to testis-sparing surgery, provided that the maximum size of the lesion is <2 cm, preoperative testosterone is normal and adjuvant radiotherapy of the residual parenchyma is delivered. Cancer-specific survival is excellent, local recurrence rate very low and androgen supplementation unlikely.
authors.affiliation: Department of Urology, University of Pisa, Pisa, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Giannarini
authors.forename: Andrea
authors.initials: A
authors.lastname: Mogorovich
authors.forename: Irene
authors.initials: I
authors.lastname: Bardelli
authors.forename: Francesca
authors.initials: F
authors.lastname: Manassero
authors.forename: Cesare
authors.initials: C
authors.lastname: Selli