Regulatory T cells: context matters.
Regulatory T cells are important for ensuring that the immune system does not attack self and does not overreact to external antigens. Understanding how these cells develop and maintain stable function provides general insights into cellular differentiation in general, as well as new opportunities for therapeutic manipulation.
Waldmann
Herman
H
Sir William Dunn School of Pathology, South Parks Road, Oxford, OX1 3RE, UK. herman.waldmann@path.ox.ac.uk
Cobbold
Stephen
S
D000818:Animals; D051858:Forkhead Transcription Factors / Q000276:immunology; D006084:Graft Rejection / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism; D023001:Transplantation Tolerance / Q000276:immunology*
D051858:Forkhead Transcription Factors