Clinical challenges: chemotherapy-induced peripheral neuropathy.
OBJECTIVE
To discuss the challenges associated with treating pain and altered sensations due to chemotherapy-induced peripheral neuropathy (CIPN).


METHODS
Published research articles and clinical experience.


CONCLUSIONS
Although there are still great challenges associated with preventing and treating pain and altered sensations due to CIPN, there are preventative strategies and therapeutic options that can certainly improve the quality of life of patients who have cancer.


CONCLUSIONS
Oncology nurses can gain a better understanding of the available pharmacologic and nonpharmacologic strategies that can prevent and reduce pain associated with chemotherapy-induced neuropathy.
Paice
Judith A
JA
Cancer Pain Program, Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. j-paice@northwestern.edu
D000700:Analgesics / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D019317:Evidence-Based Medicine; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000451:nursing; D024802:Nurse's Role; D009723:Nurse-Patient Relations; D009730:Nursing Assessment; D015404:Nursing Methodology Research; D009859:Oncology Nursing / Q000379:methods*; D010166:Palliative Care / Q000379:methods*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000451:nursing*; D011788:Quality of Life
D000700:Analgesics; D000927:Anticonvulsants; D000970:Antineoplastic Agents