Vitek2 system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications.
Qnr determinants have now been found worldwide. In 2008, among 6150 Enterobacteriaceae, 12 isolates belonging to different bacterial species showing an unusual quinolone resistance pattern on Vitek2 system were investigated. Of 12, 11 harbored a qnr gene. Without QRDR modifications, qnr genes can be detected based on a Vitek2 resistance phenotype.
Corvec
Stéphane
S
Service de Bactériologie-Hygiène hospitalière, CHU de Nantes, 9 quai Moncousu, 44093 Nantes Cedex 01, France. stephane.corvec@chu-nantes.fr
Crémet
Lise
L
Reynaud
Alain
A
Lepelletier
Didier
D
Caroff
Nathalie
N
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000254:growth & development*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015363:Quinolones / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D015363:Quinolones