title: [Peri-operative management of amiodarone patients.].
abstract: OBJECTIVE
  Amiodarone is quite an effective anti-arrhythmic drug indicated for controlling ventricular and supra-ventricular arrhythmias, and it is being widely administered in clinical practice. However, its chronic use may be associated to severe side effects which may be worsened by anesthetic-surgical acts, thus increasing the risk of such procedures. This study aimed at reviewing major amiodarone effects and relating them to anesthetic procedures.
  
  
  BACKGROUND
  The study covers major amiodarone properties, its clinical use, as well as major adverse effects, which may increase patient's surgical risk.
  
  
  CONCLUSIONS
  Amiodarone, although normally safe and effective, may present adverse effects, especially on cardiovascular system, during anesthetic-surgical procedures. This is possibly due to interactions between this drug and anesthetic agents mainly related to general anesthesia. There are reports on severe, treatment - resistant bradycardias as well as on different degrees of atrioventricular block (AVB). Patients should be carefully monitored, especially during major procedures, and vasoactive drugs (isoproterenol) and temporary artificial pacemaker, should be available because they may be critical during the adverse effects treatment.
authors.affiliation: Universidade de Brasília.
authors.forename: Gilson
authors.initials: G
authors.lastname: Ramos
authors.forename: José
authors.initials: J
authors.lastname: Ramos Filho
authors.forename: Edisio
authors.initials: E
authors.lastname: Pereira
authors.forename: Salustiano
authors.initials: S
authors.lastname: Gabriel Neto
authors.forename: Enio
authors.initials: E
authors.lastname: Chaves