title: Kinetics of substrate oxidation and hydrogen peroxide production by Mycoplasma mycoides subsp. mycoides Large Colony (LC) type and Mycoplasma mycoides subsp. capri.
abstract: Mycoplasma mycoides subsp. mycoides Large Colony (LC) type is a pathogen of goats causing contagious agalactia and respiratory disease, found on all continents where small ruminants are kept. It shares close genetic characteristics with M. mycoides subsp. capri. Substrate oxidation by 22 strains of M. mycoides subsp. mycoides LC from nine countries was compared with that of eight strains of M. mycoides subsp. capri from five countries. There was considerable similarity in the substrates used, but substrate saturation coefficients (K(s)) varied for different substrates. Substrate utilization patterns and K(s) values did not (1) significantly differentiate the LC strains from each other, (2) show any correlation with geographical origin, or (3) distinguish the LC strains from the capri strains. These results support previous studies justifying the reclassification of these subspecies as a single species.
authors.affiliation: Department of Life Sciences, King's College London, Franklin Wilkins Building, London SE19NH, UK.
authors.forename: Masoud
authors.initials: M
authors.lastname: Shahram
authors.forename: Robin A J
authors.initials: RA
authors.lastname: Nicholas
authors.forename: Roger J
authors.initials: RJ
authors.lastname: Miles
authors.forename: Ann P
authors.initials: AP
authors.lastname: Wood
authors.forename: Donovan P
authors.initials: DP
authors.lastname: Kelly
mesh_terms: D003470:Culture Media; D006861:Hydrogen Peroxide / Q000378:metabolism*; D007700:Kinetics; D009176:Mycoplasma mycoides / Q000145:classification* / Q000378:metabolism*; D010084:Oxidation-Reduction
chemical_list: D003470:Culture Media; D006861:Hydrogen Peroxide