[Spondylarthropathies].
Spondylarthropathies include the ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis of inflammatory bowel disease (Crohn disease, ulcerative colitis), some juvenile arthritis and undifferenciated spondylarthropathies. These diseases are linked together by a basic elementary lesion, enthesitis, common clinical and radiological features (sacroiliitis, spondylitis, peripheral arthritis, extra-articular manifestations), and association with HLA B27 antigen. Prevalence of spondylarthropathies in France is estimated at 0.3%, with no difference between women and men. Therapeutic option associate physical therapy and anti-inflammatory drugs. In case of insufficient efficacy of these conventional drugs, TNFalpha antagonist therapy can be used in axial forms, after disease modifying drugs in peripheral forms.
Lekpa
Fernando Kemta
FK
Service de rhumatologie, CHU Albert Chenevier-Henri Mondor, AP-HP, UFR Médecine Paris-XII, 94010 Créteil Cedex.
Farrenq
Valérie
V
Claudepierre
Pascal
P
D006801:Humans; D025242:Spondylarthropathies / Q000175:diagnosis / Q000628:therapy