title: Hepatitis B vaccination targeted at behavioural risk groups in the Netherlands: does it work?
abstract: In November 2002, the Netherlands adopted a vaccination program targeted at behavioural risk groups. Between January 2003 and December 2007, 1386 patients acutely infected with HBV were reported. Reported cases declined from 326 in 2003 to 220 in 2007. Sexual intercourse was the most frequently reported mode of transmission (65%), especially among men having sex with men. Genotypes A and D remained predominant. In total, 40,600 participants were fully vaccinated, the overall compliance was 62%, and the estimated overall program coverage was 12% of the at-risk population. With more effort, more susceptibles may be reached, but the program will not be sufficient to substantially reduce HBV in the Netherlands. Therefore, universal vaccination should be considered.
authors.affiliation: Public Health Service, Department of Infectious Diseases, Amsterdam, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: van Houdt
authors.forename: F D H
authors.initials: FD
authors.lastname: Koedijk
authors.forename: S M
authors.initials: SM
authors.lastname: Bruisten
authors.forename: E L M Op de
authors.initials: EL
authors.lastname: Coul
authors.forename: M L A
authors.initials: ML
authors.lastname: Heijnen
authors.forename: Q
authors.initials: Q
authors.lastname: Waldhober
authors.forename: I K
authors.initials: IK
authors.lastname: Veldhuijzen
authors.forename: J H
authors.initials: JH
authors.lastname: Richardus
authors.forename: M
authors.initials: M
authors.lastname: Schutten
authors.forename: G J J
authors.initials: GJ
authors.lastname: van Doornum
authors.forename: R A
authors.initials: RA
authors.lastname: de Man
authors.forename: S J
authors.initials: SJ
authors.lastname: Hahné
authors.forename: R A
authors.initials: RA
authors.lastname: Coutinho
authors.forename: H J
authors.initials: HJ
authors.lastname: Boot
mesh_terms: D000328:Adult; D005260:Female; D005838:Genotype; D006510:Hepatitis B Antibodies / Q000097:blood; D006512:Hepatitis B Core Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics; D006801:Humans; D017589:Immunization Programs; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D014611:Vaccination
chemical_list: D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D017325:Hepatitis B Vaccines