title: A tale of two compartments: interstitial versus blood glucose monitoring.
abstract: Self-monitoring of blood glucose was described as one of the most important advancements in diabetes management since the invention of insulin in 1920. Recent advances in glucose sensor technology for measuring interstitial glucose concentrations have challenged the dominance of glucose meters in diabetes management, while raising questions about the relationships between interstitial and blood glucose levels. This article will review the differences between interstitial and blood glucose and some of the challenges in measuring interstitial glucose levels accurately.
authors.affiliation: Section of Pediatric Endocrinology and Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, Connecticut 06520, USA. Eda.Cengiz@yale.edu
authors.forename: Eda
authors.initials: E
authors.lastname: Cengiz
authors.forename: William V
authors.initials: WV
authors.lastname: Tamborlane
mesh_terms: D001160:Arterioles / Q000503:physiopathology; D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000379:methods*; D003920:Diabetes Mellitus / Q000097:blood*; D045604:Extracellular Fluid / Q000502:physiology*; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods / Q000639:trends; D015203:Reproducibility of Results; D012867:Skin / Q000098:blood supply*; D014699:Venules / Q000503:physiopathology
chemical_list: D001786:Blood Glucose