title: Bone: Use of bisphosphonates in children-proceed with caution.
abstract: A clinical review of studies on bisphosphonate therapy for pediatric osteoporosis has revealed that they increase BMD, but whether they also improve fracture rates or functions of daily life is unclear. Can the findings of this clinical review help inform clinicians whether, when and how to use these agents in children?
authors.forename: Joan C
authors.initials: JC
authors.lastname: Marini
mesh_terms: D015519:Bone Density / Q000187:drug effects; D002648:Child; D004164:Diphosphonates / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy*
chemical_list: D004164:Diphosphonates