Basal cell carcinoma of the eyelid with exceptional histomorphologic expressions.
A basal cell carcinoma of the eyelid had unique and potentially confusing histopathologic features. The tumor displayed a carcinoma in situ pattern with replacement of an extensive segment of the tarsal epithelium by neoplastic basaloid cells, a finding to the best of the authors' knowledge that has not been previously documented. Within the infiltrating component of the dermis were classical solid basaloid nests and lobules; they were accompanied, however, by a separate and exceptionally prominent component of duct-like (pseudoglandular) units mimicking a microcystic adnexal carcinoma.
Jakobiec
Frederick A
FA
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA. fred_jakobiec@meei.harvard.edu
Hanna
Eissa
E
Townsend
Daniel J
DJ
D000368:Aged; D002280:Basal Cell Carcinoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry