Stereotactic body radiation therapy for oligometastases.
The standard treatment for metastatic cancer is systemic therapy. However, in a subset of patients with limited extracranial metastases or oligometastases, local ablative therapy in combination with systemic therapy may improve treatment outcomes. Stereotactic body radiation therapy (SBRT) has emerged as a novel approach for local ablation of extracranial oligometastases. There is a good body of experience in the use of SBRT for the treatment of oligometastases in various sites including the lung, the liver and the spine with promising results. This article provides an overview of the use of SBRT in the management of extracranial oligometastases.
Lo
Simon S
SS
Department of Radiation Medicine, Arthur G James Cancer Hospital, Ohio State University Medical Center, 300 West 10th Avenue, Ste 088A, Columbus, OH 43210, USA. simon.lo@osumc.edu
Fakiris
Achilles J
AJ
Teh
Bin S
BS
Cardenes
Higinia R
HR
Henderson
Mark A
MA
Forquer
Jeffrey A
JA
Papiez
Lech
L
McGarry
Ronald C
RC
Wang
Jian Z
JZ
Li
Kaile
K
Mayr
Nina A
NA
Timmerman
Robert D
RD
D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery*; D016634:Radiosurgery; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*