Synthesis of 3,6-branched arabinogalactan-type tetra- and hexasaccharides for characterization of monoclonal antibodies.
Synthesis of tetra- and hexasaccharides built up from a beta-(1-->6)-linked galactopyranosyl backbone with arabinofuranosyl side chains at position 3 and with a 3-aminopropyl spacer related to arabinogalactans is described. These oligosaccharides were prepared for investigation of monoclonal antibodies raised against arabinogalactan proteins (AGPs) from pressed juice of Echinacea purpurea.
Fekete
Anikó
A
Research Group for Carbohydrates of the Hungarian Academy of Sciences, H-4010, Debrecen, PO Box 94, Hungary.
Borbás
Anikó
A
Antus
Sándor
S
Lipták
András
A
D000911:Antibodies, Monoclonal / Q000276:immunology*; D002240:Carbohydrate Sequence; D020900:Echinacea / Q000276:immunology* / Q000378:metabolism*; D005685:Galactans / Q000737:chemistry / Q000276:immunology*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry / Q000276:immunology*
D000911:Antibodies, Monoclonal; D005685:Galactans; D009844:Oligosaccharides; C005653:arabinogalactan