title: Time to pregnancy after a previous miscarriage in subfertile couples.
abstract: OBJECTIVE
  To assess the time to spontaneous ongoing pregnancy after a previous miscarriage in subfertile couples.
  
  
  METHODS
  A prospective cohort study.
  
  
  METHODS
  The study was conducted in 38 fertility centers in the Netherlands.
  
  
  METHODS
  Subfertile couples who miscarried after completing their basic fertility work-up.
  
  
  METHODS
  Expectant management after a miscarriage.
  
  
  METHODS
  Spontaneous ongoing pregnancy.
  
  
  RESULTS
  We included 5,663 subfertile couples, of which 1,098 (19%) conceived spontaneously. Among these 1,098 couples, 199 (18%) miscarried and these couples were included in the present study. Follow-up was completed for 171 couples, of which 95 conceived again within 24 months of follow-up. Of these 95 pregnancies, 86 (91%) were ongoing. The cumulative spontaneous ongoing pregnancy rate (PR) after 24 months was 70% (95% confidence interval [CI] 59%-81%).
  
  
  CONCLUSIONS
  Subfertile couples, who experience a treatment-independent pregnancy resulting in a miscarriage, have very good prospects of a spontaneous ongoing pregnancy in the near future. This information is useful in counseling couples who had a miscarriage after a previous period of subfertility.
authors.affiliation: Department of Obstetrics and Gynecology, St. Antonius Hospital, Nieuwegein, The Netherlands. T.Cox@antonius.net
authors.forename: Tessa
authors.initials: T
authors.lastname: Cox
authors.forename: Jan-Willem
authors.initials: JW
authors.lastname: van der Steeg
authors.forename: Pieternel
authors.initials: P
authors.lastname: Steures
authors.forename: Peter G A
authors.initials: PG
authors.lastname: Hompes
authors.forename: Fulco
authors.initials: F
authors.lastname: van der Veen
authors.forename: Marinus J C
authors.initials: MJ
authors.lastname: Eijkemans
authors.forename: Jules H Schagen
authors.initials: JH
authors.lastname: van Leeuwen
authors.forename: Cees
authors.initials: C
authors.lastname: Renckens
authors.forename: Patrick M M
authors.initials: PM
authors.lastname: Bossuyt
authors.forename: Ben W J
authors.initials: BW
authors.lastname: Mol
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology*; D003376:Counseling; D005260:Female; D006801:Humans; D007246:Infertility / Q000453:epidemiology*; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011379:Prognosis; D011446:Prospective Studies; D027724:Reproductive Techniques, Assisted / Q000706:statistics & numerical data*; D013997:Time Factors