Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation.
An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBS buffer (pH 7.4) at room temperature.
Zhang
Hailong
H
Department of Chemistry, Cleveland State University, Cleveland, OH 44115, USA.
Ma
Yong
Y
Sun
Xue-Long
XL
D005947:Glucose / Q000737:chemistry*; D007700:Kinetics; D008081:Liposomes
D008081:Liposomes; D005947:Glucose