title: Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compounds.
abstract: Rat bone marrow stem cells (rBMSCs) in the presence of chemical molecules were differentiated into neurons.
authors.affiliation: Nanobio Fusion Research Center, Korea Research Institute of Chemical Technology, Yuseung, Daejon, Korea.
authors.forename: Mi Hee
authors.initials: MH
authors.lastname: Cho
authors.forename: Jung Hwa
authors.initials: JH
authors.lastname: Lee
authors.forename: Hyun Hee
authors.initials: HH
authors.lastname: Ahn
authors.forename: Ju Young
authors.initials: JY
authors.lastname: Lee
authors.forename: E Sle
authors.initials: ES
authors.lastname: Kim
authors.forename: Yun Mi
authors.initials: YM
authors.lastname: Kang
authors.forename: Byoung Hyun
authors.initials: BH
authors.lastname: Min
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Hai Bang
authors.initials: HB
authors.lastname: Lee
authors.forename: Moon Suk
authors.initials: MS
authors.lastname: Kim
mesh_terms: D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000378:metabolism; D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D015870:Gene Expression / Q000187:drug effects; D005904:Glial Fibrillary Acidic Protein / Q000235:genetics; D007150:Immunohistochemistry; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D015394:Molecular Structure; D004676:Myelin Basic Protein / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics; D016900:Neurofilament Proteins / Q000235:genetics; D055495:Neurogenesis / Q000187:drug effects*; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D011687:Purines / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013997:Time Factors; D014212:Tretinoin / Q000494:pharmacology
chemical_list: D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases; D051792:Basic Helix-Loop-Helix Proteins; D005904:Glial Fibrillary Acidic Protein; D004676:Myelin Basic Protein; D009419:Nerve Tissue Proteins; D016900:Neurofilament Proteins; D010751:Phosphopyruvate Hydratase; D011687:Purines; D014212:Tretinoin; C544546:N-(4-methoxybenzyl)-N-methyl-9H-purine-2,6-diamine; C544545:N-cyclopentyl-N-(4-methoxybenzyl)-9-methyl-9H-purine-2,6-diamine; C093564:Neurogenic differentiation factor 1