title: [Nested variant of urothelial carcinoma. A rare histological variant].
abstract: The nested variant of urothelial carcinoma is a rare histological tumor of urinary bladder. The clinical symptoms are similar to those of the classic urothelial carcinomas. Its macroscopic appearance can be very subtle due to its preference for a submucosal growth leading to a possible delay in diagnosis. Microscopically, it is characterized by nests and tubules formation. While the neoplastic cells exhibit low-grade histological features, the growth pattern is widely infiltrative conferring this neoplasia a bad prognosis even if a radical treatment is performed. We present a case of a patient affected by a nested variant of urothelial carcinoma of urinary bladder to whom a radical cystoprostatectomy was performed and adjuvant chemotherapy was given. He is alive and free of disease one year after the diagnosis.
authors.affiliation: Servicios de Urología, Hospital de Tortosa Verge de la Cinta, Tarragona. jmmestre@terra.es
authors.forename: Joaquín
authors.initials: J
authors.lastname: Marti Mestre
authors.forename: Daniel
authors.initials: D
authors.lastname: Cañis Sánchez
authors.forename: Abdelmounin
authors.initials: A
authors.lastname: El Boutaibi
authors.forename: Mario E
authors.initials: ME
authors.lastname: Mendoza Cárcamo
authors.forename: Jorge
authors.initials: J
authors.lastname: Delagneau Ribas
authors.forename: Joaquín
authors.initials: J
authors.lastname: Jaén Martínez
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000145:classification / Q000473:pathology*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000145:classification / Q000473:pathology*