title: Clinical results after implantation of a spherical aberration-free intraocular lens: effect of contrast sensitivity and wavefront aberration--a clinical comparative study.
abstract: OBJECTIVE
  To compare the clinical results of the spherical aberration-free Akreos AO (Bausch & Lomb) with the Akreos Adapt (Bausch & Lomb), the parent model of spherical optic design.
  
  
  METHODS
  Fifty patients (100 eyes) were randomly assigned to bilaterally receive Akreos AO or Akreos Adapt intraocular lenses (IOLs) after phacoemulsification. At 6 months postoperatively, best-corrected contrast sensitivities were determined at 3, 4.8, 7.5, 12 and 19 cycles per degree using a Visual Capacity Analyzer (L2 Informatique) under mesopic (5 cd/m(2)) and photopic (100 cd/m(2)) conditions with undilated pupils. Wavefront analysis of total aberration was performed with the WaveScan WaveFront System (Advanced Medical Optics VISX).
  
  
  RESULTS
  Postoperative contrast sensitivities were not statistically different under mesopic and photopic conditions. On the other hand, fourth-order spherical aberration was lower in the AO group than the Adapt group with only a marginal difference (p = 0.048). Other higher-order aberrations such as coma and trefoil were not significantly different between the two groups (p = 0.657, 0.614). The questionnaire on subjective visual quality in terms of glare disability, distant vision and night driving did not reveal an improved visual function in the AO group.
  
  
  CONCLUSIONS
  The spherical aberration-free Akreos AO IOL did not show improved visual quality compared with its spherical counterpart.
authors.affiliation: Department of Ophthalmology and Visual Science, Kangnam St. Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, Korea.
authors.forename: Jin-A
authors.initials: JA
authors.lastname: Choi
authors.forename: Chan-Young
authors.initials: CY
authors.lastname: Kim
authors.forename: Kyung-Sun
authors.initials: KS
authors.lastname: Na
authors.forename: Shin-Hae
authors.initials: SH
authors.lastname: Park
authors.forename: Choun-Ki
authors.initials: CK
authors.lastname: Joo
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D015350:Contrast Sensitivity / Q000502:physiology*; D005260:Female; D019466:Glare; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D018918:Phacoemulsification; D011379:Prognosis; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology*; D012029:Refraction, Ocular / Q000502:physiology*; D012030:Refractive Errors / Q000503:physiopathology*; D011795:Surveys and Questionnaires