title: Acute myocardial infarction with sumatriptan: a case report and review of the literature.
abstract: We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases. A 54-year-old woman with a history of migraine without aura, mild arterial hypertension, depression, and no history of coronary artery disease was admitted to our hospital for acute myocardial infarction, 30 minutes after using 6 mg of subcutaneous sumatriptan. Coronary angiography performed several days later revealed a normal coronary arterial system. Although at discharge the patient was advised to permanently avoid triptans, she continued the use of oral sumatriptan at low dosage (25-50 mg) without any problems.
authors.affiliation: Department of Neurology and Neurophysiology, S. Maria del Prato Hospital, Feltre, Bologna, Italy.
authors.forename: Flavio Devetag
authors.initials: FD
authors.lastname: Chalaupka
mesh_terms: D000208:Acute Disease; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000503:physiopathology; D003331:Coronary Vessels / Q000187:drug effects* / Q000503:physiopathology; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000150:complications; D007279:Injections, Subcutaneous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000503:physiopathology; D018170:Sumatriptan / Q000009:adverse effects*; D016896:Treatment Outcome; D014661:Vasoconstriction / Q000187:drug effects / Q000502:physiology; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D000319:Adrenergic beta-Antagonists; D014662:Vasoconstrictor Agents; D018170:Sumatriptan; D006493:Heparin; D001241:Aspirin