EEG-fMRI coregistration in non-ketotic hyperglycemic occipital seizures.
We report the first case, to our knowledge, of non-ketotic hyperglycemic (NKH) related occipital seizures studied by continuous EEG-fMRI in an undiagnosed diabetic patient. Ictal EEG showed left posterior spikes and sharp-waves. Seizures subsided after insulin therapy was started. Continuous EEG-fMRI was performed and BOLD activation was identified in the left Brodmann's area 18 (visual association area). Activation of an epileptic focus related with the patient's metabolic disturbance can be postulated.
Del Felice
Alessandra
A
Department of Neurological and Visual Science, University of Verona, Italy.
Zanoni
Tiziano
T
Avesani
Mirko
M
Formaggio
Emanuela
E
Storti
Silvia
S
Fiaschi
Antonio
A
Moretto
Giuseppe
G
Manganotti
Paolo
P
D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D004569:Electroencephalography; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007091:Image Processing, Computer-Assisted; D007328:Insulin / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009778:Occipital Lobe / Q000473:pathology* / Q000503:physiopathology; D010100:Oxygen / Q000097:blood; D012640:Seizures / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon
D000927:Anticonvulsants; D007004:Hypoglycemic Agents; D007328:Insulin; D002220:Carbamazepine; D010100:Oxygen