title: Effect of oil-based calcium hydroxide (Osteoinductal) on distraction osteogenesis in rabbit mandible.
abstract: OBJECTIVE
  The objective of this study was to evaluate the effects of oil-based calcium hydroxide on mandibular lengthening during distraction osteogenesis.
  
  
  METHODS
  Twenty-four New Zealand white rabbits underwent unilateral mandibular osteotomy. The rabbits were divided into 4 groups containing 6 each: groups 1 and 3 were control groups and groups 2 and 4 were test groups. Oil-based calcium hydroxide suspension was applied to test groups' corticotomy gap after osteotomy during operation. No treatment was applied to the control groups. After 5 days' latency period, distraction was commenced at a rate of 0.8 mm/day for 10 days via custom-made distractor. Groups 1 and 2 were killed 14 days after distraction and groups 3 and 4 were killed 28 days after distraction.
  
  
  RESULTS
  Quantitative computerized tomography evaluation did not demonstrate a difference mean the density and the area of the regeneration between groups 1 and 3, but there was a significant difference groups 2 and 4. Histomorphometric evaluation demonstrated that there was a significant difference between test and control groups in new bone volume formation during distraction osteogenesis.
  
  
  CONCLUSIONS
  Application of oil-based calcium hydroxide paste during the osteotomy phase of distraction osteogenesis increased regeneration and new bone volume formation.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Cumhuriyet University, Sivas, Turkey. hidayetpolat@yahoo.com
authors.forename: Hidayet Burak
authors.initials: HB
authors.lastname: Polat
authors.forename: Hasan
authors.initials: H
authors.lastname: Yeler
authors.forename: Cesur
authors.initials: C
authors.lastname: Gumus
authors.forename: Huseyin Eray
authors.initials: HE
authors.lastname: Bulut
authors.forename: Dervishan
authors.initials: D
authors.lastname: Kucuk
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000494:pharmacology*; D002146:Bony Callus / Q000187:drug effects; D002126:Calcium Hydroxide / Q000494:pharmacology*; D019186:Mandibular Advancement / Q000379:methods*; D010012:Osteogenesis / Q000187:drug effects*; D019857:Osteogenesis, Distraction / Q000379:methods*; D011817:Rabbits
chemical_list: D018786:Bone Substitutes; C112450:Osteoinductal; D002126:Calcium Hydroxide