title: A system for the determination of planar lipid bilayer breakdown voltage and its applications.
abstract: In this paper, we focus on measurement principles used in electroporation studies on planar lipid bilayers. In particular, we point out the voltage-clamp measurement principle that has great importance when the breakdown voltage of a planar lipid bilayer is under consideration; however, it is also appropriate for the determination of other planar lipid bilayer electrical properties such as resistance and capacitance. A new experimental system that is based on the voltage-clamp measurement principle is described. With the use of a generator that can generate arbitrary-type signals, many specific shapes of a voltage signal could be generated, and therefore, the experimental system is appropriate for a broad spectrum of measurements.
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Ljubljana SI-1000, Slovenia. peter.kramar@fe.uni-lj.si
authors.forename: Peter
authors.initials: P
authors.lastname: Kramar
authors.forename: Damijan
authors.initials: D
authors.lastname: Miklavcic
authors.forename: Alenka Macek
authors.initials: AM
authors.lastname: Lebar
mesh_terms: D004558:Electric Stimulation / Q000295:instrumentation*; D004563:Electrochemistry / Q000379:methods*; D004574:Electromagnetic Fields; D018274:Electroporation / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008051:Lipid Bilayers / Q000737:chemistry*; D018408:Patch-Clamp Techniques / Q000295:instrumentation*
chemical_list: D008051:Lipid Bilayers