[Study on chemical constituents and antimicrobial activity of the essential oil from Acanthopanax brachypus].
OBJECTIVE
The chemical constituents and antimicrobial activity of the essential oil from Acanthopanax brachypus were studied.


METHODS
The essential oil was extracted from the stem of A. brachypus by steam distillation, and its antimicrobial activity was tested in vitro. The chemical constituents were separated and identified by GC-MS, and the relative contents of each constituent was determined by area normalization.


RESULTS
The essential oil showed some certain antibacterial activities against the tested strains escherichia coli, bacillus subtilis, staphylococcus aureus, pseudomonas aeruginosa and candida albicans except aspergillus niger. Forty-seven constituents were separated and identified, accounting for 91.37% of the total oil. The main constituent were Heptanoic acid (7.05%), Vanillin (6.09%), trans-Linalool oxide (6.07%), 1-methyl-2-(-methylethyl)-Benaene (5.83%), alpha-Phellandrene (5.14%), n-Hexadecanoic acid (5.15%) and beta-Myrcene (5.07%).


CONCLUSIONS
The essential oil of A. brachypus contained varied active constituent, has a certain antimicrobial activity, this result will provide some scientific references for the pharmacological further research of A. brachypus.
Hu
Huai-sheng
HS
Department of chemistry and chemical engiering, Longdong University, Qingyang 745000, China.
Hu
Hao-bin
HB
Zheng
Xu-dong
XD
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001547:Benzaldehydes / Q000032:analysis; D000081005:Cyclohexane Monoterpenes; D028001:Eleutherococcus / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D006538:Heptanoic Acids / Q000032:analysis*; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D010169:Palmitic Acids / Q000032:analysis; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D001547:Benzaldehydes; D000081005:Cyclohexane Monoterpenes; D006538:Heptanoic Acids; D039821:Monoterpenes; D009822:Oils, Volatile; D010169:Palmitic Acids; C005403:alpha phellandrene; C100058:vanillin