title: Cemented total hip arthroplasty in a patient with alpha-mannosidosis: a case report.
abstract: Mannosidosis is an extremely rare genetic disease occurring due to deficiency of the lysosomal enzyme, alpha-mannosidase. Patients with this disorder often suffer from musculoskeletal abnormalities and muscular weakness leading to joint destruction and severe morbidity along with other major systems involvement. We present here such a case of a 27-year-old male that highlights the challenges in management of hip joint destruction secondary to Mannosidosis.
authors.affiliation: Centre for Hip surgery, Wrightington Hospital, Wigan, UK. desaiaravind@yahoo.co.uk
authors.forename: Aravind S
authors.initials: AS
authors.lastname: Desai
authors.forename: Asterios
authors.initials: A
authors.lastname: Dramis
authors.forename: Timothy N
authors.initials: TN
authors.lastname: Board
authors.forename: Peter R
authors.initials: PR
authors.lastname: Kay
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D001860:Bone Plates; D006617:Hip Dislocation / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007592:Joint Diseases / Q000209:etiology* / Q000601:surgery*; D008297:Male; D012086:Reoperation; D008363:alpha-Mannosidosis / Q000150:complications*