Determination of sun protection factors in the hairless mouse.
Synopsis A laboratory method for determining sun protection factors (SPF) in the hairless mouse has been developed. The ability of the method to predict the SPF in man has been investigated using sunscreen ingredients and finished products with known activities in man. The results indicate that the hairless mouse can be used to assess sunscreen products although the SPF found appeared slightly higher than that determined in man.
James
C N
CN
Toxicol Laboratories Limited, Bromyard Road, Ledbury, Herefordshire HR8 1LG.
Middleton
J D
JD