Reticulated acanthoma with sebaceous differentiation. Lack of association with Muir-Torre syndrome.
We hereby report a case of a reticulated acanthoma with sebaceous differentiation (RASD), a rare and often mislabeled benign lesion that is characterized by epidermal acanthosis and clusters of sebocytes in a reticulated seborrheic keratosis-like pattern. The presence of multiple sebaceous tumors, most notably cystic sebaceous adenomas and keratoacanthomas, has been associated with Muir-Torre syndrome (MTS). Although very rare, cases of RASD have been reported with MTS, which potentially offers profound clinical significance to this neoplasm. This case further supports the lack of association of MTS with RASD.
Haake
Dana L
DL
Dermpath Diagnostics South Florida, Pompano Beach, FL 33069, USA.
Minni
John P
JP
Nowak
Michael
M
Abenoza
Pascual
P
Nousari
Carlos H
CH
D049309:Acanthoma / Q000473:pathology*; D000369:Aged, 80 and over; D001706:Biopsy; D002454:Cell Differentiation; D006801:Humans; D008297:Male; D055653:Muir-Torre Syndrome; D012627:Sebaceous Glands / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*