title: Adrenal insufficiency and other adrenal oncologic emergencies.
abstract: Normal function of the adrenal gland can be disrupted not only by metastases of nonadrenal cancers but also by their treatment. In addition, tumors of the adrenal gland itself can cause disease by hypersecretion of a variety of hormones, adrenal gland destruction with inadequate production of cortisol, and by metastasis to other sites. Although rare, abnormal adrenal function should be considered in the appropriate clinical settings as failure to recognize and treat can result in significant morbidity and mortality. The adrenal "incidentaloma" is a frequent finding of abdominal radiologic studies. All patients with an unexpected adrenal mass should be referred for further evaluation.
authors.affiliation: Department of Emergency Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, Bolwell 3700, Cleveland, OH 44106, USA.
authors.forename: Yael R
authors.initials: YR
authors.lastname: Taub
authors.forename: Robert W
authors.initials: RW
authors.lastname: Wolford
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000556:secondary; D000309:Adrenal Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D004630:Emergencies; D005440:Fluid Therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D008901:Mineralocorticoids / Q000627:therapeutic use; D010911:Pituitary Neoplasms / Q000150:complications*; D010913:Pituitary-Adrenal System / Q000502:physiology
chemical_list: D008901:Mineralocorticoids; D006854:Hydrocortisone