Primary giant clear cell sarcoma (soft tissue malignant melanoma) of the sternum.
One case of a primary clear cell sarcoma of the sternum (also called soft tissue melanoma) is reported. This neoplasm represents a rare occurrence, and as a rule, differential diagnosis with melanoma often requires detailed immunohistochemistry and cytogenetic analysis (ie, rearrangement of EWS gene localized on 22q12 chromosome). Because wide resection is recommended, chest wall reconstruction may pose challenging technical issues. In our patient, we elected not to proceed to clavicular stabilization. Nevertheless, acceptable shoulder girdle mobility was observed after surgery.
Rocco
Gaetano
G
Department of Thoracic Surgery and Oncology, National Cancer Institute, Pascale Foundation, IRCCS, Naples, Italy. gaetano.rocco@btopenworld.com
de Chiara
Anna Rosaria
AR
Fazioli
Flavio
F
Scognamiglio
Francesco
F
La Rocca
Antonello
A
Apice
Gaetano
G
Riva
Carla
C
D001859:Bone Neoplasms / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D018227:Sarcoma, Clear Cell / Q000601:surgery; D013249:Sternum