GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information.
GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. This integrative approach has proved to be useful for the interpretation of high-throughput experiments and therefore a new version of the system has been developed to expand its functionality and scope. GeneCodis now expands the functional information with regulatory patterns and user-defined annotations, offering the possibility of integrating all sources of information in the same analysis. Traditional singular enrichment is now permitted and more organisms and gene identifiers have been added to the database. The application has been re-engineered to improve performance, accessibility and scalability. In addition, GeneCodis can now be accessed through a public SOAP web services interface, enabling users to perform analysis from their own scripts and workflows. The application is freely available at http://genecodis.dacya.ucm.es.
Nogales-Cadenas
Ruben
R
Computer Architecture Department, Complutense University of Madrid, Madrid, Spain.
Carmona-Saez
Pedro
P
Vazquez
Miguel
M
Vicente
Cesar
C
Yang
Xiaoyuan
X
Tirado
Francisco
F
Carazo
Jose María
JM
Pascual-Montano
Alberto
A
D000818:Animals; D002417:Cattle; D005786:Gene Expression Regulation; D005796:Genes; D006801:Humans; D020407:Internet; D051379:Mice; D035683:MicroRNAs / Q000378:metabolism; D051381:Rats; D012984:Software; D018511:Systems Integration; D014157:Transcription Factors / Q000378:metabolism; D014584:User-Computer Interface
D035683:MicroRNAs; D014157:Transcription Factors