Multiple pathways for the irreversible inhibition of steroid sulfatase with quinone methide-generating suicide inhibitors.
Ahmed
Vanessa
V
Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L3G1, Canada.
Liu
Yong
Y
Taylor
Scott D
SD
D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D045563:Indolequinones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D007700:Kinetics; D043266:Steryl-Sulfatase / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004791:Enzyme Inhibitors; D045563:Indolequinones; C068040:quinone methide; D043266:Steryl-Sulfatase