title: First detection of neuropeptide Y (NPY)-like immunoreactivity in the lateral line: presence and distribution in the neuromasts of the Antarctic notothenioid fish Trematomus bernacchii.
abstract: The mechanosensory lateral line (LL) is involved in many fish and amphibian behaviors, however little is known about the molecules involved in the signal transmission. Neuropeptide Y (NPY) has a number of functions in vertebrate physiology and also plays important roles in different sensory systems. The Antarctic nototheniods are a monophyletic radiation of fishes that have evolved under the extreme environmental conditions of low light and cold, where non-visual sensory structures, such as LL, are of importance. In this study we describe the presence of NPY-like immunoreactivity (IR) in LL of the Antarctic nototheniod fish, Trematomus bernacchii Boulenger. Differences in size and cellular composition between the two neuromasts were in compliance with previous descriptions of these sensory organs. Despite structural and functional differences between canal and superficial neuromasts, the distribution of NPY-like IR was similar within both the receptors classes. In particular, NPY IR was observed in all three cell types which constitute these sensory organs, allowing us to hypothesize the involvement of this molecule in the processing of the sensory information.
authors.affiliation: ISPRA, c/o National Antarctic Museum, University of Genoa, Viale Benedetto XV 5, I-16132 Genoa, Italy. m.bottaro@unige.it
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Bottaro
authors.forename: Sara
authors.initials: S
authors.lastname: Ferrando
authors.forename: Silvia
authors.initials: S
authors.lastname: Ravera
authors.forename: Marino
authors.initials: M
authors.lastname: Vacchi
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Gallus
authors.forename: Chiara
authors.initials: C
authors.lastname: Gambardella
authors.forename: Grazia
authors.initials: G
authors.lastname: Tagliafierro
mesh_terms: D000818:Animals; D000864:Antarctic Regions; D005399:Fishes / Q000033:anatomy & histology*; D053403:Lateral Line System / Q000166:cytology* / Q000378:metabolism*; D008465:Mechanoreceptors / Q000378:metabolism; D009478:Neuropeptide Y / Q000378:metabolism*
chemical_list: D009478:Neuropeptide Y