Primary yolk sac tumor of the lung.
Yolk-sac tumor mimics the yolk sac of the embryo, and the presence of alpha fetoprotein in the tumor cells is highly characteristic. We present an 18-year-old boy with primary pulmonary yolk-sac tumor diagnosed postoperatively. A computed tomographic scan revealed a huge intrathoracic soft tissue mass 20 x 25 cm occupying most of the left hemithorax. Two trials of computed tomographic-guided needle biopsy were nonconclusive. A left upper lobectomy was performed with a complete tumor resection. Postoperatively, the patient's alpha fetoprotein (AFP) was 10,512 IU/mL with gradual decline under chemotherapy. The patient is alive 10 months after surgery and is disease free.
Abdel Rahman
Abdel Rahman M
AR
Department of Surgery, National Cancer Institute, Cairo, Egypt.
Ebied
Emad N
EN
Nouh
Mohamed A
MA
Gal
Anthony A
AA
Mansour
Kamal A
KA
D000293:Adolescent; D018240:Endodermal Sinus Tumor / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male