Selective quantification of carnitine enantiomers using chiral cysteine-capped CdSe(ZnS) quantum dots.
We report the first observation of selective and specific recognition of chiral L-cysteine (L-Cys)- or D-cysteine (D-Cys)-capped CdSe(ZnS) quantum dots (QDs) with carnitine enantiomers in aqueous solution. The intensity fluorescence of L-Cys-capped QDs decay in the presence of D-carnitine but are not affected by L-carnitine. On the other hand, the fluorescence of D-Cys-capped QDs was only affected by L-carnitine. The applicability of chiral Cys-capped QDs for the analysis of chiral mixtures on enantiomers has been demonstrated for 1:100 mixtures, and the results that were obtained had high precision (<2.3%) and low error (<2.7%).
Carrillo-Carrión
Carolina
C
Department of Analytical Chemistry, University of Córdoba, E-14071 Córdoba, Spain.
Cárdenas
Soledad
S
Simonet
Bartolomé M
BM
Valcárcel
Miguel
M
D019187:Cadmium Compounds / Q000737:chemistry*; D002331:Carnitine / Q000032:analysis* / Q000737:chemistry; D003545:Cysteine / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013237:Stereoisomerism; D019287:Zinc Sulfate / Q000737:chemistry*
D019187:Cadmium Compounds; D018036:Selenium Compounds; D019287:Zinc Sulfate; C058667:cadmium selenide; D003545:Cysteine; D002331:Carnitine