Iron(III)-catalyzed and air-mediated tandem reaction of aldehydes, alkynes and amines: an efficient approach to substituted quinolines.
Economic and practical advantages are offered by the iron(III)-catalyzed and air-mediated tandem coupling/hydroarylation/dehydrogenation of simple readily available aldehydes, alkynes, and amines for the synthesis of 2, 4-disubstituted quinolines (see scheme).
Cao
Ke
K
State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, China.
Zhang
Fu-Min
FM
Tu
Yong-Qiang
YQ
Zhuo
Xiao-Tao
XT
Fan
Chun-An
CA
D000447:Aldehydes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010293:Pargyline / Q000031:analogs & derivatives / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
D000447:Aldehydes; D000480:Alkynes; D000588:Amines; D005290:Ferric Compounds; D011437:Propylamines; D011804:Quinolines; C009054:propargylamine; D010293:Pargyline