title: New clerodane diterpenoids from Casearia sylvestris.
abstract: Two new clerodane diterpenoids 2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide (1) and 15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide (2) and one new nitrogen-containing clerodane diterpenoid 15-oxo-echinophyllin A (3), along with six known compounds, namely, echinophyllin A, (-)-patagonic acid, tyrosol, oplopanone, 4-hydroxy-4-methyl-2-[(1R)-1-(1-methylethyl)-4-oxopentyl]-2-cyclohexen-1-one and 1 beta,6 alpha-dihydroxy-eudesman-4(15)-ene were isolated from the leaves of Casearia sylvestris. Their structures were determined by extensive NMR techniques.
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, MS 38677, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Zulfiqar
authors.initials: Z
authors.lastname: Ali
authors.forename: Xing-Cong
authors.initials: XC
authors.lastname: Li
authors.forename: Troy A
authors.initials: TA
authors.lastname: Smillie
authors.forename: De-An
authors.initials: DA
authors.lastname: Guo
authors.forename: Ikhlas A
authors.initials: IA
authors.lastname: Khan
mesh_terms: D037821:Casearia / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
chemical_list: C544788:15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide; C544786:2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide; D004224:Diterpenes; D045785:Diterpenes, Clerodane; D010936:Plant Extracts