Long-term results of central venous access devices in children with haemophilia.
OBJECTIVE
Central venous access devices (CVADs) are often used to provide reliable venous access for factor VIII administration in children with haemophilia. This study investigates their long-term outcome.


METHODS
A retrospective cohort study of 44 CVADs inserted into 31 children with haemophilia at a single centre between 1991 and 2006.


RESULTS
Eight (18%) CVADs are still in place and working well. Fourteen (31.8%) were removed when the child was able to return to peripheral vascular access. Twenty-two (50%) were removed because of complications, most of these children needing a replacement CVAD. The median duration that the first CVAD was in place was 51 months. There were no life-threatening complications.


CONCLUSIONS
CVADs function well in children with haemophilia for a long time, with a relatively low complication rate, and can tide a child over a difficult period for vascular access.
Upadhyaya
Manasvi
M
Department of Paediatric Surgery, University Hospital of Wales, Cardiff, UK. manasviu@hotmail.com
Richards
Michael
M
Buckham
Sarah
S
Squire
B R
BR
D000293:Adolescent; D002405:Catheterization, Central Venous; D002408:Catheters, Indwelling; D002648:Child; D002675:Child, Preschool; D003029:Coagulants / Q000008:administration & dosage*; D015331:Cohort Studies; D005169:Factor VIII / Q000008:administration & dosage*; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans; D007223:Infant; D012189:Retrospective Studies
D003029:Coagulants; D005169:Factor VIII