[Study on Diels-Alder type adducts from stem barks of Morus yunanensis].
OBJECTIVE
To isolate and identify the Diels-Alder type adducts from stem barks of Morus yunanensis.


METHODS
The compounds were isolated and purified by silicagel, Sephadex LH-20 and RP-18 colum chromatography. Their chemical structures were elucidated on the basis ofphysicochemical properties and spectral data.


RESULTS
Nine compounds were isolated and identified as: kuwanon G (1), sanggenol M (2), mulberrofuran J (3), guangsangon B (4), resveratrol (5), kuwanon X (6), kuwanon P (7), mulberrofuran O (8), mulberrofuran Q (9).


CONCLUSIONS
All the compounds are isolated from the plant for the first time, and compounds 4, 5 have anti-inflammation activities with inhibitory ratios of 57.3%, 50.5% respectively at a concentration of 10 microg mL(-1).
Cui
Xiqiang
X
Key Laboratory of Bioactive substance and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Peking Union College and Chinese Academy of Medical Science, Beijing 100050, China.
Chen
Hui
H
Chen
Ruoyun
R
D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D004365:Drugs, Chinese Herbal; D005419:Flavonoids / Q000032:analysis; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D000077185:Resveratrol; D013267:Stilbenes / Q000032:analysis
D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; D013267:Stilbenes; C095194:kuwanon G; D000077185:Resveratrol