title: Bile acid-based polyaminocarboxylate conjugates as targeted antitumor agents.
abstract: Bile acid-polyaminocarboxylate conjugates containing NE3TA, a potential iron chelator displayed significant cytotoxicities in both HeLa and HT29 colon cancer cells, and cholic acid-NE3TA attached to an organic fluorophore was shown to enter the HT29 cancer cells.
authors.affiliation: Chemistry Division, Biological, Chemical, and Physical Sciences Department, Illinois Institute of Technology, Chicago, IL, USA. chong@iit.edu
authors.forename: Hyun-Soon
authors.initials: HS
authors.lastname: Chong
authors.forename: Hyun A
authors.initials: HA
authors.lastname: Song
authors.forename: Xiang
authors.initials: X
authors.lastname: Ma
authors.forename: Sooyoun
authors.initials: S
authors.lastname: Lim
authors.forename: Xiang
authors.initials: X
authors.lastname: Sun
authors.forename: Santosh B
authors.initials: SB
authors.lastname: Mhaske
mesh_terms: D000588:Amines / Q000737:chemistry; D000970:Antineoplastic Agents / Q000737:chemistry*; D001647:Bile Acids and Salts / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D045744:Cell Line, Tumor; D006801:Humans; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence
chemical_list: D000588:Amines; D000970:Antineoplastic Agents; D001647:Bile Acids and Salts; D002264:Carboxylic Acids