Amanita phalloides poisoning-induced end-stage renal failure.
Fungi poisoning is quite frequent: in particular, Amanita phalloides has life-threatening toxicity. It is responsible for fulminant hepatitis, and also has renal toxicity. Herein, we report on a patient who developed acute renal failure after ingesting A. phalloides, which required definitive renal replacement therapy, despite rapid liver injury recovery. A kidney biopsy showed massive acute tubular necrosis, mainly in the proximal convoluted tubule, and mild interstitial infiltration by mononuclear cells.
Garrouste
C
C
Department of Nephrology, Tarbes, University Hospital, CHU Rangueil, Toulouse, France.
Hémery
M
M
Boudat
A M
AM
Kamar
N
N
D000368:Aged; D000545:Amanita / Q000302:isolation & purification / Q000472:pathogenicity*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D009145:Mushroom Poisoning / Q000150:complications* / Q000175:diagnosis; D006435:Renal Dialysis / Q000379:methods