title: Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening.
abstract: Many countries have introduced newborn screening for cystic fibrosis to facilitate diagnosis prior to the development of lung disease. Although most infants with cystic fibrosis are asymptomatic from a respiratory point of view at diagnosis, structural lung disease has been detected by computed tomography. We present a case of an asymptomatic infant with cystic fibrosis diagnosed following newborn screening who had endobronchial infection with Pseudomonas aeruginosa and radiological evidence of bronchiectasis at 3 months of age.
authors.affiliation: Division of Clinical Sciences, Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, PO Box 855, West Perth, WA, 6872, Australia.
authors.forename: Lauren S
authors.initials: LS
authors.lastname: Mott
authors.forename: Catherine L
authors.initials: CL
authors.lastname: Gangell
authors.forename: Conor P
authors.initials: CP
authors.lastname: Murray
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Stick
authors.forename: Peter D
authors.initials: PD
authors.lastname: Sly
mesh_terms: D001987:Bronchiectasis / Q000000981:diagnostic imaging* / Q000209:etiology*; D018893:Bronchoalveolar Lavage; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening; D011552:Pseudomonas Infections / Q000150:complications; D014057:Tomography, X-Ray Computed