The Society of Thoracic Surgeons practice guideline series: guidelines for the management of Barrett's esophagus with high-grade dysplasia.
The management of Barrett's esophagus with high-grade dysplasia is controversial. The standard of care has traditionally been esophagectomy. However, a number of treatment options aimed at esophageal preservation are increasingly being utilized by many centers. These esophageal-sparing approaches include endoscopic surveillance, mucosal ablation, and endoscopic mucosal resection. In this guideline we review the best evidence supporting these commonly used strategies for high-grade dysplasia to better define management and guide future investigation.
Fernando
Hiran C
HC
Boston University School of Medicine and Department of Cardiothoracic Surgery, Boston Medical Center, Boston, Massachussetts 02118, USA. hiran.fernando@bmc.org
Murthy
Sudish C
SC
Hofstetter
Wayne
W
Shrager
Joseph B
JB
Bridges
Charles
C
Mitchell
John D
JD
Landreneau
Rodney J
RJ
Clough
Ellen R
ER
Watson
Thomas J
TJ
D001471:Barrett Esophagus / Q000473:pathology / Q000628:therapy*; D001706:Biopsy; D017115:Catheter Ablation; D016629:Esophagectomy; D004945:Esophagoscopy; D006801:Humans; D018579:Patient Selection; D010778:Photochemotherapy; D011159:Population Surveillance