Gracillosides A-F, six new 8,14-seco-pregnane glycosides from Adelostemma gracillimum.
Six new 8,14-seco-pregnane glycosides, gracillosides A-F (1-6), were isolated from the roots of Adelostemma gracillimum (Asclepiadaceae). All of them had the same aglycone as gracigenin with a rare 8,14-seco-pregnane type skeleton in nature and possessed an oligosaccharide chain consisting of four to six sugar units at C-3 of the aglycone. Their structures were determined on the basis of detailed spectroscopic analysis and chemical evidence.
Gao
Zhu-Lin
ZL
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China.
He
Hong-Ping
HP
Di
Ying-Tong
YT
Fang
Xin
X
Li
Chun-Shun
CS
Liu
Hai-Yang
HY
Zhou
Qian-Lan
QL
Mu
Quan-Zhang
QZ
Hao
Xiao-Jiang
XJ
D029062:Apocynaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification*
D006027:Glycosides; D011278:Pregnanes