title: Long-term results of central venous access devices in children with haemophilia.
abstract: OBJECTIVE
  Central venous access devices (CVADs) are often used to provide reliable venous access for factor VIII administration in children with haemophilia. This study investigates their long-term outcome.
  
  
  METHODS
  A retrospective cohort study of 44 CVADs inserted into 31 children with haemophilia at a single centre between 1991 and 2006.
  
  
  RESULTS
  Eight (18%) CVADs are still in place and working well. Fourteen (31.8%) were removed when the child was able to return to peripheral vascular access. Twenty-two (50%) were removed because of complications, most of these children needing a replacement CVAD. The median duration that the first CVAD was in place was 51 months. There were no life-threatening complications.
  
  
  CONCLUSIONS
  CVADs function well in children with haemophilia for a long time, with a relatively low complication rate, and can tide a child over a difficult period for vascular access.
authors.affiliation: Department of Paediatric Surgery, University Hospital of Wales, Cardiff, UK. manasviu@hotmail.com
authors.forename: Manasvi
authors.initials: M
authors.lastname: Upadhyaya
authors.forename: Michael
authors.initials: M
authors.lastname: Richards
authors.forename: Sarah
authors.initials: S
authors.lastname: Buckham
authors.forename: B R
authors.initials: BR
authors.lastname: Squire
mesh_terms: D000293:Adolescent; D002405:Catheterization, Central Venous; D002408:Catheters, Indwelling; D002648:Child; D002675:Child, Preschool; D003029:Coagulants / Q000008:administration & dosage*; D015331:Cohort Studies; D005169:Factor VIII / Q000008:administration & dosage*; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans; D007223:Infant; D012189:Retrospective Studies
chemical_list: D003029:Coagulants; D005169:Factor VIII