title: An overview of the safety of sucralose.
abstract: Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is the non-nutritive sweetener in retail SPLENDA Sweetening Products, composed of sucralose and common food ingredients. A review of the extensive body of evidence that supports the safety of sucralose is provided. The results of an independent review of a new study investigating the safety of a sucralose-mixture retail product, Granulated SPLENDA No Calorie Sweetener, are also discussed. The collective evidence supports the conclusion that the ingredient, sucralose, is safe for use in food and that the sucralose-mixture product, Granulated SPLENDA No Calorie Sweetener, is also safe for its intended use.
authors.affiliation: McNeil Nutritionals, LLC, 601 Office Center Dr., Fort Washington, PA 19034, USA. LGrotz@its.jnj.com
authors.forename: V Lee
authors.initials: VL
authors.lastname: Grotz
authors.forename: Ian C
authors.initials: IC
authors.lastname: Munro
mesh_terms: D000818:Animals; D001835:Body Weight; D003257:Consumer Product Safety; D004040:Dietary Carbohydrates; D006801:Humans; D051381:Rats; D013395:Sucrose / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D013549:Sweetening Agents / Q000009:adverse effects / Q000737:chemistry / Q000378:metabolism; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D004040:Dietary Carbohydrates; D013549:Sweetening Agents; D013395:Sucrose; C026285:trichlorosucrose