title: Indoles from simple anilines and alkynes: palladium-catalyzed C-H activation using dioxygen as the oxidant.
abstract: Pd doles it out: A palladium-catalyzed approach to indoles using the title reaction was achieved (see scheme). The oxidant used in this catalytic cycle was O(2). Both N-nonsubstituted and N-alkyl monosubstituted anilines can be successfully transformed into the corresponding indoles by this method.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100083, China.
authors.forename: Zhuangzhi
authors.initials: Z
authors.lastname: Shi
authors.forename: Chun
authors.initials: C
authors.lastname: Zhang
authors.forename: Si
authors.initials: S
authors.lastname: Li
authors.forename: Delin
authors.initials: D
authors.lastname: Pan
authors.forename: Shengtao
authors.initials: S
authors.lastname: Ding
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Cui
authors.forename: Ning
authors.initials: N
authors.lastname: Jiao
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D007211:Indoles; D016877:Oxidants; D010165:Palladium; D010100:Oxygen; C023650:aniline