title: Dispersion of multidrug-resistant Enterococcus faecium isolates belonging to major clonal complexes in different Portuguese settings.
abstract: The population structure of 56 Enterococcus faecium isolates selected from a collection of enterococci from humans, animals, and the environment in Portugal (1997 to 2007) was analyzed by multilocus sequence typing. We identified 41 sequence types clustering into CC17, CC5, CC9, CC22 and CC94, all clonal lineages comprising isolates from different hosts. Our findings highlight the role of community-associated hosts as reservoirs of enterococci able to cause human infections.
authors.affiliation: REQUIMTE, Laboratório de Microbiologia, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
authors.forename: Ana R
authors.initials: AR
authors.lastname: Freitas
authors.forename: Carla
authors.initials: C
authors.lastname: Novais
authors.forename: Patricia
authors.initials: P
authors.lastname: Ruiz-Garbajosa
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Coque
authors.forename: Luísa
authors.initials: L
authors.lastname: Peixe
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D016172:DNA Fingerprinting / Q000379:methods; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D016984:Enterococcus faecium / Q000145:classification* / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D004783:Environmental Microbiology; D005838:Genotype; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology* / Q000662:veterinary*; D006801:Humans; D017720:Molecular Epidemiology; D011174:Portugal; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial