title: Brucellar epididymo-orchitis: review of 53 cases in Babol, northern Iran.
abstract: From September 1998 to December 2008, 53 cases of brucellar epididymo-orchitis were treated and followed. The mean age of the patients was 35.5+/-15.9 y. 26 (49.1%) subjects had orchitis. Scrotal pain and swelling, fever, sweating, and arthralgia or arthritis occurred in 53 (100%), 43 (84.3%), 40 (78.4%) and 25 (47.1%) cases, respectively. 16, 20, 9 and 8 cases were treated with gentamicin for 7 d plus doxycycline for 45 d (GD), cotrimoxazole plus doxycycline (CD) for 45 d, streptomycin for 2 weeks and doxycycline (SD) for 45 d, and cotrimaxazole plus rifampin (CR) for 45 d, respectively. We continued the oral agents in all regimens for 2 months in those not clinically cured. At 45 d, cure rates were 48.3%, 65%, 77.8% and 50%, respectively, and at 2 months they were 87.5%, 90%, 100% and 75%, for GD, CD, SD and CR, respectively. In conclusion, scrotal pain and swelling, fever, sweating and arthralgia or arthritis were the main clinical findings in brucellar epididymo-orchitis patients. An aminoglycoside containing combination therapy was usually efficacious. Cotrimoxazole plus doxycycline may be an alternative regimen for those who cannot take an aminoglycoside.
authors.affiliation: Department of Infectious Diseases, Yahyanejad Hospital, Babol Medical University, Babol. hagar2q@yahoo.ca
authors.forename: Mohammad Reza Hasanjani
authors.initials: MR
authors.lastname: Roushan
authors.forename: Masomeh
authors.initials: M
authors.lastname: Baiani
authors.forename: Mostafa
authors.initials: M
authors.lastname: Javanian
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Kasaeian
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002002:Brucella / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D004823:Epididymitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009920:Orchitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology; D012307:Risk Factors; D014463:Ultrasonography
chemical_list: D000900:Anti-Bacterial Agents