title: Oral Kaposi sarcoma: a case of immune reconstitution inflammatory syndrome.
abstract: Wider use of highly active antiretroviral treatment (HAART) for human immunodeficiency virus-1 (HIV-1)-infected patients has significantly altered the pattern of acquired immunodeficiency syndrome (AIDS)-related clinical signs and symptoms and has revolutionized the therapeutic modalities for these patients. Immune reconstitution inflammatory syndrome (IRIS) is a paradox of clinical worsening of opportunistic infections in the context of response to HAART and immunological recovery. Here we present a case of oral IRIS-related Kaposi sarcoma (KS) that appeared in an advanced HIV-1-infected patient introduced to HAART and was treated by surgical removal and antiretroviral therapy.
authors.affiliation: King's College London, London, UK.
authors.forename: Zoi
authors.initials: Z
authors.lastname: Papagatsia
authors.forename: Judith
authors.initials: J
authors.lastname: Jones
authors.forename: Peter
authors.initials: P
authors.lastname: Morgan
authors.forename: Anwar R
authors.initials: AR
authors.lastname: Tappuni
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D000998:Antiviral Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D010157:Palatal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis
chemical_list: D000998:Antiviral Agents