title: Resin-based versus gutta-percha-based root canal obturation: influence on bacterial leakage in an in vitro model system.
abstract: OBJECTIVE
  This study evaluated the ability of a resin-based system (Resilon/Epiphany) and gutta-percha/sealer with warm vertical or cold lateral compaction to prevent coronal leakage.
  
  
  METHODS
  A polymicrobial suspension in a dual-chamber model was used. Seventy extracted maxillary incisors were prepared, divided into 4 groups, and obturated: Group 1, lateral compaction/gutta-percha/AH Plus; Group 2, lateral compaction/Resilon; Group 3, continuous wave compaction/gutta-percha/AH Plus; Group 4, continuous wave compaction/Resilon. Upper chambers held a mixed suspension of endodontic pathogens. Apices were suspended in the lower chambers. Leakage was determined daily for 40 days and evaluated for turbidity. Data were analyzed using survival analysis; log-rank test was used to analyze differences in time to leakage.
  
  
  RESULTS
  Median time to leakage: 16, 15, 11, and 25 days for Groups 1 to 4 respectively (P = .93, log-rank test).
  
  
  CONCLUSIONS
  No difference in time to leakage among the 4 treatment groups existed.
authors.affiliation: Department of Endodontics, University of Iowa College of Dentistry, Iowa City, IA 52241, USA. anne-williamson@uiowa.edu
authors.forename: Anne E
authors.initials: AE
authors.lastname: Williamson
authors.forename: Kristy L
authors.initials: KL
authors.lastname: Marker
authors.forename: David R
authors.initials: DR
authors.lastname: Drake
authors.forename: Deborah V
authors.initials: DV
authors.lastname: Dawson
authors.forename: Richard E
authors.initials: RE
authors.lastname: Walton
mesh_terms: D003763:Dental Leakage / Q000382:microbiology / Q000517:prevention & control*; D003786:Dental Pulp Cavity / Q000382:microbiology; D019232:Dental Restoration Failure; D004853:Epoxy Resins / Q000737:chemistry; D006171:Gutta-Percha / Q000737:chemistry; D006801:Humans; D007180:Incisor; D008137:Longitudinal Studies; D008437:Maxilla; D012387:Root Canal Filling Materials / Q000737:chemistry*; D012389:Root Canal Obturation / Q000379:methods*
chemical_list: D004853:Epoxy Resins; D012387:Root Canal Filling Materials; C534916:epoxy resin-based root canal sealer; C486892:resilon sealer; D006171:Gutta-Percha