title: [Study on prognostic factors of chronic severe hepatitis].
abstract: OBJECTIVE
  To analyze factors influencing prognosis and to develop a prognosis predicting model for patients with chronic severe hepatitis.
  
  
  METHODS
  Clinical data from 408 patients suffering from chronic severe hepatitis were divided into improved group and deteriorated group. The main clinical and laboratory variables were analyzed as predictive factors of prognosis with logistic regression analysis.
  
  
  RESULTS
  It was shown that age, sex, TBil, DBil, [Cl-], [Na+], WBC, MCV, PT, NH3, PTA, and BUN were different between the two groups with statistical significance (P < 0.05). The prognosis predicting model was P = 1/(1 + e(-y)), Y = -4.636 + 0.022X1 + 0.034X2 + 0.096X3 + 0.047X4 - 0.042X5, (X1-age, X2-TBil, X3-BUN, X4-MCV, X5-PTA).
  
  
  CONCLUSIONS
  Age, TBil, BUN, MCV and PTA are the independent risk factors related to prognosis of chronic severe hepatitis.
authors.affiliation: Department of Hepatology, Beijing You An Hospital, Capital Medical University, Beijing 100069, China.
authors.forename: Qing-hu
authors.initials: QH
authors.lastname: Meng
authors.forename: Zhong-hui
authors.initials: ZH
authors.lastname: Duan
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Yu
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Ya
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Hou
authors.forename: Ya
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D006521:Hepatitis, Chronic / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors