title: Diffuse large B-cell lymphoma with massive portal vein tumor thrombosis in a patient with alcoholic cirrhosis: a case report and literature review.
abstract: We describe a case of diffuse large B-cell lymphoma with massive portal vein tumor thrombosis in a patient with alcoholic cirrhosis. The tumor was detected only in the intrahepatic portal vein and the spermatic cord by FDG-PET/CT. Percutaneous liver biopsy and orchiectomy were performed and histological examination revealed diffuse large B-cell lymphoma. The tumor showed complete response after six courses of the combination chemotherapy. Portal vein tumor thrombosis of malignant lymphoma is extremely rare; moreover, it is possible that this is the first case of malignant lymphoma originating from the spermatic cord producing portal vein tumor thrombosis.
authors.affiliation: Department of Gastroenterology, Sapporo Hokuyu Hospital, Sapporo. tosho@hokuyu-aoth.org
authors.forename: Mitsuteru
authors.initials: M
authors.lastname: Natsuizaka
authors.forename: Mineo
authors.initials: M
authors.lastname: Kudo
authors.forename: Mio
authors.initials: M
authors.lastname: Suzuki
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Takano
authors.forename: Masako
authors.initials: M
authors.lastname: Tsuyuguchi
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kawamura
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Noguchi
authors.forename: Akinori
authors.initials: A
authors.lastname: Wada
authors.forename: Masanobu
authors.initials: M
authors.lastname: Nakata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ogasawara
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kiyama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Asaka
authors.forename: Masaharu
authors.initials: M
authors.lastname: Kasai
mesh_terms: D000368:Aged; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011169:Portal Vein / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013085:Spermatic Cord / Q000473:pathology; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18