Overview of gene targeting by homologous recombination.
Formerly UNIT 9.15, this unit has been moved to the opening spot of our new chapter on Embryonic Stem Cell technology. The unit has also been updated, and now includes information about the Cre-lox and FlP/FRT recombinase systems.
Mortensen
Richard
R
University of Michigan Medical Center, Ann Arbor, Michigan, USA.
D000818:Animals; D002460:Cell Line; D003001:Cloning, Molecular; D053595:Embryonic Stem Cells; D018390:Gene Targeting / Q000379:methods*; D051379:Mice; D008817:Mice, Mutant Strains; D009154:Mutation; D011401:Promoter Regions, Genetic; D011995:Recombination, Genetic