title: Biophysical dissection of membrane proteins.
abstract: The first atomic-resolution structure of a membrane protein was solved in 1985. Twenty-four years and more than 180 unique structures later, what have we have learned? An examination of the atomic details of several diverse membrane proteins reveals some remarkable biophysical features and suggests that we can expect to achieve much more in the decades to come.
authors.affiliation: Department of Physiology and Biophysics, and Center for Biomembrane Systems, University of California, Irvine, California 92697, USA. stephen.white@uci.edu
authors.forename: Stephen H
authors.initials: SH
authors.lastname: White
mesh_terms: D020816:Amino Acid Motifs; D000818:Animals; D001703:Biophysics; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism*; D017433:Protein Structure, Secondary; D015398:Signal Transduction
chemical_list: D008051:Lipid Bilayers; D008565:Membrane Proteins