Adult onset Schönlein-Henoch purpura associated with Helicobacter pylori infection.
Schönlein-Henoch purpura (SHP) is a systemic vasculitis, primarily involving the skin, gastrointestinal (GI) tract, joints, and kidneys. A wide variety of different conditions may be implicated in the pathogenesis of SHP. We report a 33-year-old man who presented with SHP accompanied by gastric Helicobacter pylori (Hp) infection. The GI manifestations and purpuric rashes were dramatically resolved after Hp eradication therapy. To date, very few publications have focused on the possible pathogenetic relationship between Hp infection and SHP.
Hoshino
Chisho
C
Ohta-Nishinouchi Hospital, General Internal Medicine, Koriyama. gim-hoshino@ohta-hp.or.jp
D000328:Adult; D017668:Age of Onset; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016099:Endoscopy, Gastrointestinal; D005756:Gastritis / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D041981:Gastrointestinal Tract / Q000473:pathology; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016480:Helicobacter pylori / Q000472:pathogenicity; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008297:Male
D000900:Anti-Bacterial Agents