title: Appearance of ring sideroblasts in bone marrow during linezolid therapy.
abstract: A female patient with renal dysfunction developed thrombocytopenia after 2 weeks of linezolid treatment. Her bone marrow showed abnormal erythroblast morphology and abundant ring sideroblasts. No chromosomal abnormalities or other signs of myelodysplasia were seen in an early follow-up bone marrow aspirate, where the abnormal morphological findings had almost totally subsided.
authors.affiliation: Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland. freja.ebeling@hus.fi
authors.forename: Freja
authors.initials: F
authors.lastname: Ebeling
authors.forename: Päivi
authors.initials: P
authors.lastname: Helminen
authors.forename: Veli-Jukka
authors.initials: VJ
authors.lastname: Anttila
mesh_terms: D000081:Acetamides / Q000009:adverse effects*; D000890:Anti-Infective Agents / Q000009:adverse effects*; D001707:Biopsy, Needle; D001792:Blood Platelets / Q000187:drug effects / Q000473:pathology; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology*; D004900:Erythroblasts / Q000187:drug effects / Q000473:pathology*; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D006801:Humans; D000069349:Linezolid; D008875:Middle Aged; D023303:Oxazolidinones / Q000009:adverse effects*; D010976:Platelet Count
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid