[Updated reproductive function of human sperm RNA].
The existence of RNA has been confirmed in human mature sperm, including mRNA and some members of the microRNA family. Different expressions of sperm mRNA have been found to be correlated with sperm motility and male reproduction. Some sperm specific mRNA and microNA play important roles in the regulation of sperm-oocyte fusion and early embryogenesis. Many published results indicate the variety of sperm RNA in composition and quantity as well as its indispensability for embryogenesis. Further researches on the function of sperm RNA will promote the progress in such fields as male infertility, human assisted reproduction technology and nuclear transfer.
Niu
Zhi-hong
ZH
Fudan University School of Medicine, Shanghai 200032, China. kangniu@sina.com
Shi
Hui-juan
HJ
Zhang
Hui-qin
HQ
D006801:Humans; D008297:Male; D035683:MicroRNAs / Q000502:physiology*; D012333:RNA, Messenger / Q000502:physiology*; D013081:Sperm Motility; D013094:Spermatozoa / Q000502:physiology*
D035683:MicroRNAs; D012333:RNA, Messenger