A Janus-like role of CREB protein: enhancement of synaptic property in mature neurons and suppression of synaptogenesis and reduced network synchrony in early development.
Nonaka
Mio
M
Department of Neurochemistry, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan. nonaka@m.u-tokyo.ac.jp
D000818:Animals; D001921:Brain / Q000166:cytology* / Q000196:embryology; D050882:CREB-Binding Protein / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D051786:Cyclic AMP Response Element Modulator / Q000235:genetics / Q000378:metabolism; D051379:Mice; D055495:Neurogenesis / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D013569:Synapses / Q000502:physiology*
D051786:Cyclic AMP Response Element Modulator; D050882:CREB-Binding Protein