title: Vector retargeting for cancer gene therapy.
abstract: Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy. Vector retargeting is one of the important strategies on viral vector targeting. This review mainly focused on the progresses of vector retargeting in cancer gene therapy, and summarized relevant pathways and strategies.
authors.affiliation: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.forename: Jing-lun
authors.initials: JL
authors.lastname: Xue
authors.forename: Ling
authors.initials: L
authors.lastname: Tian
mesh_terms: D001360:Avidin; D001710:Biotin; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000235:genetics*; D016679:Genome, Viral; D006801:Humans; D008024:Ligands; D009369:Neoplasms / Q000628:therapy*; D011993:Recombinant Fusion Proteins; D018523:Tropism
chemical_list: D008024:Ligands; D011993:Recombinant Fusion Proteins; D001360:Avidin; D001710:Biotin