Comparative study of framework surgery and fat injection laryngoplasty.
OBJECTIVE
To evaluate differences between the functional results of framework surgery and autologous fat injection laryngoplasty, for patients with unilateral vocal fold paralysis.


METHODS
Sixty-two patients underwent framework surgery, while 64 received autologous fat injection laryngoplasty. Voice function before and after both procedures was assessed using aerodynamic and acoustic analysis, with differences evaluated using paired t-test in both groups.


RESULTS
In both groups, all parameters improved significantly after surgery, compared with before surgery. Post-operative improvement in all parameters was significantly greater after fat injection laryngoplasty, compared with framework surgery.


CONCLUSIONS
Autologous fat injection laryngoplasty was thus found to be a more effective and reliable therapy for improving voice function in patients with vocal fold paralysis, compared with framework surgery.
Umeno
H
H
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan. umeno2@med.kurume-u.ac.jp
Chitose
S
S
Sato
K
K
Nakashima
T
T
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007828:Laryngoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013223:Statistics as Topic; D050151:Subcutaneous Fat / Q000637:transplantation*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000601:surgery / Q000628:therapy*; D014831:Voice / Q000502:physiology; D014833:Voice Quality / Q000502:physiology*