[A comparative study of the effects of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro].
OBJECTIVE
To compare the effect of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro.


METHODS
We incubated the sperm aseptically obtained by masturbation from 12 asthenospermia men and treated by swim-up technique in Acanthopanacis senticosi injection (10 g/L), theophylline (3 mmol/L) and caffeine (7 mmol/L) respectively, and detected various sperm parameters with the computer-assisted sperm analysis (CASA) system at 0 h, 1 h and 3 h.


RESULTS
Acanthopanacis senticosi injection significantly increased sperm motility, the percentage of progressive motile sperm, straight line velocity (VSL) and curvilinear velocity (VCL) as compared with theophylline and caffeine (P < 0.05).


CONCLUSIONS
Acanthopanacis senticosi injection can activate the mobility of human sperm in vitro.
Wu
Wei
W
1. Department of Urology, The First Hospital of Wuhan, Wuhan, Hubei 430030, China. 3wviagra@sina.com
Liu
Ji-hong
JH
Yin
Chun-ping
CP
Zhang
Chuan-hua
CH
D002110:Caffeine / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D028001:Eleutherococcus / Q000737:chemistry; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D013081:Sperm Motility / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D002110:Caffeine; D013806:Theophylline