title: Primary giant clear cell sarcoma (soft tissue malignant melanoma) of the sternum.
abstract: One case of a primary clear cell sarcoma of the sternum (also called soft tissue melanoma) is reported. This neoplasm represents a rare occurrence, and as a rule, differential diagnosis with melanoma often requires detailed immunohistochemistry and cytogenetic analysis (ie, rearrangement of EWS gene localized on 22q12 chromosome). Because wide resection is recommended, chest wall reconstruction may pose challenging technical issues. In our patient, we elected not to proceed to clavicular stabilization. Nevertheless, acceptable shoulder girdle mobility was observed after surgery.
authors.affiliation: Department of Thoracic Surgery and Oncology, National Cancer Institute, Pascale Foundation, IRCCS, Naples, Italy. gaetano.rocco@btopenworld.com
authors.forename: Gaetano
authors.initials: G
authors.lastname: Rocco
authors.forename: Anna Rosaria
authors.initials: AR
authors.lastname: de Chiara
authors.forename: Flavio
authors.initials: F
authors.lastname: Fazioli
authors.forename: Francesco
authors.initials: F
authors.lastname: Scognamiglio
authors.forename: Antonello
authors.initials: A
authors.lastname: La Rocca
authors.forename: Gaetano
authors.initials: G
authors.lastname: Apice
authors.forename: Carla
authors.initials: C
authors.lastname: Riva
mesh_terms: D001859:Bone Neoplasms / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D018227:Sarcoma, Clear Cell / Q000601:surgery; D013249:Sternum