title: Titanium(IV) halide mediated coupling of alkoxides and alkynes: an efficient and stereoselective route to trisubstituted (E)-alkenyl halides.
abstract: Alkoxide C-O bond cleavage occurs readily at room temperature in the presence of titanium(IV) halide. Capture of the resultant carbocation by alkynes provides an efficient route to trisubstituted (E)-alkenyl halides with high stereoselectivity.
authors.affiliation: Department of Chemistry, The University of Tennessee, Knoxville, Tennessee 37996-1600, USA.
authors.forename: Min-Liang
authors.initials: ML
authors.lastname: Yao
authors.forename: Travis R
authors.initials: TR
authors.lastname: Quick
authors.forename: Zhongzhi
authors.initials: Z
authors.lastname: Wu
authors.forename: Michael P
authors.initials: MP
authors.lastname: Quinn
authors.forename: George W
authors.initials: GW
authors.lastname: Kabalka