Treatment of right ventricular dysfunction in pulmonary arterial hypertension: theoretical considerations.
Significant progress has been made in the medical therapy of pulmonary hypertension in recent years, but long term results are still disappointing. We describe the theoretical underpinnings of a surgical procedure which we suggest might prevent or delay the occurrence of right ventricular failure and thereby improve long-term survival in pulmonary arterial hypertension. This is a hypothesis which could be tested in an animal model of this condition.
Engel
Peter J
PJ
Pulmonary Hypertension Clinic, The Christ Hospital, Cincinnati, OH, USA. eiben.lctc@fuse.net
Baughman
Robert P
RP
D000328:Adult; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000601:surgery*; D008955:Models, Cardiovascular; D018497:Ventricular Dysfunction, Right / Q000209:etiology* / Q000517:prevention & control*