Impaired cardiac autonomic nervous control after cardiac bypass surgery for congenital heart disease.
We undertook a study to describe changes in heart rate variability (HRV) postoperatively in children undergoing cardiac bypass surgery for congenital heart disease (CHD). HRV was recorded for a 1-h period preoperatively and a 24-h period postoperatively in 20 children with CHD. We found a highly significant reduction in HRV in both time and frequency domain indices compared to preoperative values, which was sustained throughout the 24-h study period. There was a negative correlation between both time and frequency domain HRV measurements and length of cardiac bypass. HRV is reduced postoperatively and correlates with cardiac bypass time. Length of cardiac bypass time may be one mechanism whereby HRV is reduced following surgery.
McGlone
Laura
L
Princess Royal Maternity Hospital, Alexandra Parade, Glasgow, Scotland, UK. mcglonelaura@hotmail.com
Patel
Neil
N
Young
David
D
Danton
Mark D
MD
D000293:Adolescent; D001341:Autonomic Nervous System / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D015716:Electrocardiography, Ambulatory; D005260:Female; D005583:Fourier Analysis; D006321:Heart / Q000294:innervation*; D006330:Heart Defects, Congenital / Q000601:surgery*; D006339:Heart Rate; D006801:Humans; D007223:Infant; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care; D013997:Time Factors; D016896:Treatment Outcome