Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compounds.
Rat bone marrow stem cells (rBMSCs) in the presence of chemical molecules were differentiated into neurons.
Cho
Mi Hee
MH
Nanobio Fusion Research Center, Korea Research Institute of Chemical Technology, Yuseung, Daejon, Korea.
Lee
Jung Hwa
JH
Ahn
Hyun Hee
HH
Lee
Ju Young
JY
Kim
E Sle
ES
Kang
Yun Mi
YM
Min
Byoung Hyun
BH
Kim
Jae Ho
JH
Lee
Hai Bang
HB
Kim
Moon Suk
MS
D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000378:metabolism; D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D015870:Gene Expression / Q000187:drug effects; D005904:Glial Fibrillary Acidic Protein / Q000235:genetics; D007150:Immunohistochemistry; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D015394:Molecular Structure; D004676:Myelin Basic Protein / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics; D016900:Neurofilament Proteins / Q000235:genetics; D055495:Neurogenesis / Q000187:drug effects*; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D011687:Purines / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013997:Time Factors; D014212:Tretinoin / Q000494:pharmacology
D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases; D051792:Basic Helix-Loop-Helix Proteins; D005904:Glial Fibrillary Acidic Protein; D004676:Myelin Basic Protein; D009419:Nerve Tissue Proteins; D016900:Neurofilament Proteins; D010751:Phosphopyruvate Hydratase; D011687:Purines; D014212:Tretinoin; C544546:N-(4-methoxybenzyl)-N-methyl-9H-purine-2,6-diamine; C544545:N-cyclopentyl-N-(4-methoxybenzyl)-9-methyl-9H-purine-2,6-diamine; C093564:Neurogenic differentiation factor 1