Halitosis.
BACKGROUND
Halitosis can be caused by oral disease, or by respiratory tract conditions such as sinusitis, tonsillitis, and bronchiectasis, but an estimated 40% of affected individuals have no underlying organic disease.


METHODS
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments in people with physiological halitosis? We searched: Medline, Embase, The Cochrane Library and other important databases up to July 2008 (BMJ Clinical evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).


RESULTS
We found five systematic reviews, RCTs or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.


CONCLUSIONS
In this systematic review we present information relating to the effectiveness and safety of the following interventions: artificial saliva; cleaning, brushing or scraping the tongue; diet modification; regular or single use of mouthwash; sugar-free chewing gums; and zinc toothpastes.
Scully Cbe
Crispian
C
UCL - Eastman Dental Institute, London, UK.
Porter
Stephen
S
D002638:Chewing Gum; D005500:Follow-Up Studies; D006209:Halitosis; D006801:Humans; D009067:Mouthwashes; D014059:Tongue; D014100:Toothpastes; D015032:Zinc
D002638:Chewing Gum; D009067:Mouthwashes; D014100:Toothpastes; D015032:Zinc