title: Comparison of a new cardiac output ultrasound dilution method with thermodilution technique in adult patients under general anesthesia.
abstract: OBJECTIVE
  The purpose of this study was to investigate the reliability of cardiac output (CO) measured by a new ultrasound dilution method (COud) in comparison with CO by pulmonary artery thermodilution (COtd) in adult patients undergoing surgery.
  
  
  METHODS
  A prospective study.
  
  
  METHODS
  A university hospital, single institutional.
  
  
  METHODS
  Twenty-nine adult patients undergoing abdominal surgery.
  
  
  RESULTS
  After approval of the institutional ethics review board, 29 adult patients were evaluated. After induction, radial and pulmonary artery catheters were inserted. A disposable extracorporeal AV loop was connected between existing arterial and central venous catheters. Reusable ultrasound sensors that measure changes in blood ultrasound velocity after dilution by isotonic saline were clamped onto the arterial and venous limbs of the loop. Ultrasound dilution (UD) measurements (COstatus; Transonic Systems, Inc, Ithaca, NY) were obtained by injecting 30 mL of body-temperature isotonic saline into the venous limb of the AV loop. An average of 3 COud and 5 COtd was obtained for comparison. Bland-Altman plot and correlation analysis were used for statistical comparison. A total of 142 comparison measurements were obtained. The correlation coefficient between the 2 techniques was r = 0.91. Bland-Altman analysis did not produce any significant bias (bias = 0.02, standard deviation = 0.56). The percentage error of these data was 23.53%.
  
  
  CONCLUSIONS
  COud measurements agreed well with COtd. The results of this study indicated that COud might be interchangeable with conventional COtd in perioperative adult patients.
authors.affiliation: Department of Anesthesiology, National Defense Medical College, Saitama, Japan. tutuu@ca3.so-net.ne.jp
authors.forename: Masato
authors.initials: M
authors.lastname: Tsutsui
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Matsuoka
authors.forename: Takehiko
authors.initials: T
authors.lastname: Ikeda
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Sanjo
authors.forename: Tomiei
authors.initials: T
authors.lastname: Kazama
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000768:Anesthesia, General; D001783:Blood Flow Velocity; D002302:Cardiac Output; D002407:Catheterization, Swan-Ganz; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D011446:Prospective Studies; D017534:Radial Artery; D015203:Reproducibility of Results; D013815:Thermodilution / Q000379:methods*; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*