title: The evolution of the cyanobacterial posttranslational clock from a primitive "phoscillator".
abstract: Cyanobacteria were among the 1st organisms to evolve on earth. The molecular circadian clock proteins of cyanobacteria and their phylogenetics have recently been elucidated. This allows for a conjecture on the evolution of 1 of the 1st circadian clocks. A scenario has now been created by combining known in vitro and in vivo properties of the 3 clock proteins of cyanobacteria (KaiA, KaiB, and KaiC). This scenario describes the evolution of the cyanobacterial clock in gradual steps: evolving from a masking mechanism, toward an hourglass, into a clock.
authors.affiliation: Department of Chronobiology, University of Groningen, Haren, The Netherlands. m.j.p.simons@rug.nl
authors.forename: Mirre J P
authors.initials: MJ
authors.lastname: Simons
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D001683:Biological Clocks / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D056925:Circadian Rhythm Signaling Peptides and Proteins; D000458:Cyanobacteria / Q000145:classification / Q000502:physiology*; D019143:Evolution, Molecular; D017440:Photoperiod; D010802:Phylogeny
chemical_list: D001426:Bacterial Proteins; D056925:Circadian Rhythm Signaling Peptides and Proteins; C114269:KaiA protein, cyanobacteria; C114270:KaiB protein, cyanobacteria; C114271:KaiC protein, cyanobacteria; D000255:Adenosine Triphosphate