title: CT and MR imaging findings in patients with acquired heart disease at risk for sudden cardiac death.
abstract: Noninvasive imaging is an important screening and diagnostic tool in conditions associated with sudden cardiac death. The most common cause of sudden cardiac death is coronary artery disease, with myocarditis, cardiac sarcoidosis, and dilated and infiltrative cardiomyopathies being less common acquired causes. Common risk factors for sudden cardiac death, regardless of the disease process, include severe ventricular dysfunction and the presence of macroscopic scar seen at delayed contrast material-enhanced imaging. Recent advances in electrocardiographically (ECG) gated cardiac magnetic resonance (MR) imaging and multidetector computed tomography (CT) have led to increased referrals for cross-sectional imaging; thus, cardiac radiologists should be familiar with the disease entities associated with sudden cardiac death. Inflammatory processes and cardiomyopathies are best depicted with cardiac MR imaging. Steady-state free precession cine sequences coupled with inversion-recovery prepared gradient-echo T1-weighted sequences performed after the intravenous administration of gadolinium-based contrast material should form the basis of cardiac MR imaging protocols for cardiomyopathy. A clinical history that is suggestive of myocardial ischemia, specific requests to exclude coronary artery disease, or contraindications for MR imaging may imply that multidetector CT would be more appropriate. Nevertheless, both cardiac MR imaging and ECG-gated multidetector CT offer robust diagnosis and risk stratification for individual disease processes associated with sudden cardiac death.
authors.affiliation: Division of Cardiothoracic Imaging, Department of Medical Imaging, University Health Network and Mount Sinai Hospital, 200 Elizabeth St, NCBS 1-562, Toronto, ON, Canada.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Sparrow
authors.forename: Naeem
authors.initials: N
authors.lastname: Merchant
authors.forename: Yves L
authors.initials: YL
authors.lastname: Provost
authors.forename: Deirdre J
authors.initials: DJ
authors.lastname: Doyle
authors.forename: Elsie T
authors.initials: ET
authors.lastname: Nguyen
authors.forename: Narinder S
authors.initials: NS
authors.lastname: Paul
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000473:pathology; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000473:pathology; D009205:Myocarditis / Q000000981:diagnostic imaging / Q000473:pathology; D012306:Risk; D036542:Tomography, Spiral Computed; D014057:Tomography, X-Ray Computed; D055815:Young Adult