title: Association of glycemic control with risk of erectile dysfunction in men with type 2 diabetes.
abstract: BACKGROUND
  Improvement in glycemic control is likely to reduce the risk of diabetic complication, while its effect on erectile dysfunction (ED) remains unclear.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the association of glycemic control with risk of ED in type 2 diabetics.
  
  
  METHODS
  A self-administered questionnaire containing Sexual Health Inventory for Men was obtained from 792 subjects with type 2 diabetes at our institution. Clinical data were obtained through chart review.
  
  
  METHODS
  The contribution of glycemic control assessed by glycated hemoglobin (HbA(1c)) level as well as age, duration of diabetes, hypertension (HT), dyslipidemia, and cigarette smoking to risk of ED was evaluated.
  
  
  RESULTS
  Of 792 subjects, 83.6% reported having ED and 43.2% had severe ED. HbA(1c) level (%) adjusted for age and duration of diabetes was significantly associated with ED (OR 1.12, 95% CI: 1.01-1.25). None of HT, dyslipidemia, and cigarette smoking was a significant risk factor for ED after adjusted for age and duration of diabetes. HbA(1c) level, age, and duration of diabetes were significant independent risk factors for ED among the younger group (age < or = 60 years), and only age and duration of diabetes were independent risk factors among the older group (age > 60 years). For the risk of severe ED, compared with no and mild to moderate ED, HbA(1c) level, duration of diabetes, and HT were independent risk factors among the younger group, and only age was an independent factor among the older group.
  
  
  CONCLUSIONS
  Better glycemic control probably would reduce the prevalence of ED and its severity among the younger men with type 2 diabetes. For the older group, aging was the major determinant for ED risk among this population with type 2 diabetes.
authors.affiliation: Department of Internal Medicine, Division of General Medicine, Kaohsiung, Taiwan; Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
authors.forename: Chih-Chen
authors.initials: CC
authors.lastname: Lu
authors.affiliation: Department of Surgery, Division of Urology, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic address: bpjiaan@vghks.gov.tw.
authors.forename: Bang-Ping
authors.initials: BP
authors.lastname: Jiann
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
authors.forename: Chun-Chin
authors.initials: CC
authors.lastname: Sun
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
authors.forename: Hing-Chung
authors.initials: HC
authors.lastname: Lam
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Rehabilitation Technology, TzuHui Institute of Technology, Pingtung, Taiwan.
authors.forename: Chih-Hsun
authors.initials: CH
authors.lastname: Chu
authors.affiliation: Department of Pathology and Laboratory Medicine, Division of Biochemistry, Kaohsiung, Taiwan; Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Internal Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
authors.forename: Jenn-Kuen
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000453:epidemiology* / Q000378:metabolism; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000453:epidemiology*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents