State estimation, response prediction, and cerebellar sensory processing for behavioral control.
State estimation has emerged as the keystone in determining the cerebellar contribution to motor control. Clinical, experimental, and neuroimaging data converge to focus on cerebellar multisensory information processing as the mechanism allowing to correctly establish the body state needed for movement. Further, recent data indicate the cerebellum specifically involved in predicting body state changes. The present editorial discusses these evidences and questions cerebellar state estimation in the cognitive domain.
Molinari
Marco
M
IRCCS Santa Lucia Foundation, Rome, Italy. m.molinari@hsantalucia.it
Restuccia
Domenico
D
Leggio
Maria G
MG
D000818:Animals; D001519:Behavior / Q000502:physiology*; D002531:Cerebellum / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D006801:Humans; D011237:Predictive Value of Tests; D011597:Psychomotor Performance / Q000502:physiology*; D012677:Sensation / Q000502:physiology*