title: [Exercise induced anaphylaxis].
abstract: BACKGROUND
  Exercise-induced anaphylaxis (EIA) is a rare physical allergy, sometimes severe, triggered by exertion following specific food intake. Although described several years ago, this condition is not well known; the diagnosis is frequently made several years after follow up.
  
  
  OBJECTIVE
  To describe the physiopathologic mechanism, etiologic factors, clinical manifestations and diagnostic means.
  
  
  METHODS
  Review of the literature.
  
  
  RESULTS
  It is likely that execise induce the release of a sufficient amount of mediators from mast IgE dependant cells exceeding a certain threshold. A number of food trigger have been suggested in EIA, the most commonly reported agent is wheat which has to be systematically looked for. A range of physical activities have been associated with EIA. Intensive physical activities are more likely to provoke an attack than less strenuous ones. The recognition of specific food causative role do not indicate the avoidance of food intake but exercise is forbidden within the four hours following specific aliment ingestion.
  
  
  CONCLUSIONS
  Further studies seem to be necessary to clarify the mechanism of food dependent exercise-induced anaphylaxis.
authors.affiliation: Service de Pneumologie Allergologie, Centre Hospitalo, Universitaire de la Rabta, Tunis, Tunisie.
authors.forename: Nadia
authors.initials: N
authors.lastname: Mehiri
authors.forename: Besma
authors.initials: B
authors.lastname: Ourari
authors.forename: Jouda
authors.initials: J
authors.lastname: Cherif
authors.forename: Yosra
authors.initials: Y
authors.lastname: Sellami
authors.forename: Béchir
authors.initials: B
authors.lastname: Louzir
authors.forename: Jalloul
authors.initials: J
authors.lastname: Daghfous
authors.forename: Majed
authors.initials: M
authors.lastname: Beji
mesh_terms: D000707:Anaphylaxis / Q000209:etiology* / Q000503:physiopathology*; D004435:Eating / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005512:Food Hypersensitivity / Q000503:physiopathology; D006801:Humans