OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells.
van der Flier
Laurens G
LG
Hubrecht Institute, KNAW & University Medical Center Utrecht, Utrecht, The Netherlands.
Haegebarth
Andrea
A
Stange
Daniel E
DE
van de Wetering
Marc
M
Clevers
Hans
H
D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology; D014408:Biomarkers, Tumor / Q000378:metabolism*; D015179:Colorectal Neoplasms / Q000378:metabolism* / Q000473:pathology; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism*; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000378:metabolism* / Q000473:pathology; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D013234:Stem Cells / Q000378:metabolism* / Q000473:pathology
D014408:Biomarkers, Tumor; C116884:LGR5 protein, human; C454127:OLFM4 protein, human; D043562:Receptors, G-Protein-Coupled; D016179:Granulocyte Colony-Stimulating Factor