title: Management of brachial plexus region tumours and tumour-like conditions: relevant diagnostic and surgical features in a consecutive series of eighteen patients.
abstract: BACKGROUND
  Tumours of the brachial plexus region are rare and most publications are case reports or studies with a small series of patients. The aim of this study is to present our experience in managing these lesions.
  
  
  METHODS
  We review 18 patients with tumours in the brachial plexus region submitted to surgical treatment in a 6 year period, including their clinical presentation, neuro-imaging data, surgical findings and outcome.
  
  
  RESULTS
  The tumours comprised a heterogeneous group of lesions, including schwannomas, neurofibromas, malignant peripheral nerve sheath tumour (MPNST), sarcomas, metastases, desmoids and an aneurysmal bone cyst. The most common presentation was an expanding lump (83.33%). Eleven tumours were benign and 7 were malignant. Neurofibromatosis was present in only 2 patients (11.11%). Gross total resection was achieved in 14 patients and sub-total resection in the others. Only 3 patients presented with new post-operative motor deficits. The incidence of complications was low (16.5 %).
  
  
  CONCLUSIONS
  The majority of tumours were benign and most of them could be excised with a low incidence of additional deficits. Some of the malignant tumours could be controlled by surgery plus adjuvant therapy, but this category is still associated with high morbidity and mortality rates.
authors.affiliation: Peripheral Nerve Surgery Unit, Department of Neurosurgery, São Paulo University Medical School, São Paulo, SP, Brazil. mgsiqueira@uol.com.br
authors.forename: M G
authors.initials: MG
authors.lastname: Siqueira
authors.forename: R S
authors.initials: RS
authors.lastname: Martins
authors.forename: M J
authors.initials: MJ
authors.lastname: Teixeira
mesh_terms: D000293:Adolescent; D000328:Adult; D017824:Bone Cysts, Aneurysmal / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D001917:Brachial Plexus / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery*; D020516:Brachial Plexus Neuropathies / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D005260:Female; D018222:Desmoid Tumors / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000175:diagnosis / Q000503:physiopathology; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D009442:Neurilemmoma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D009455:Neurofibroma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D019635:Neurosurgical Procedures; D010146:Pain / Q000209:etiology; D010292:Paresthesia / Q000209:etiology; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012509:Sarcoma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult