title: [Prevention of itching after spinal sufentanil: effects of droperidol, nalbuphine, ondansetron and the association of them.].
abstract: OBJECTIVE
  Spinal opioids may cause some undesirable effects, the most frequent of which is itching. In spite of its low morbidity rate, itching may cause severe discomfort to patients in addition to prolonging hospital stay. This study aimed at evaluating different therapeutic options to prevent itching after spinal sufentanil.
  
  
  METHODS
  Participated in these study 100 patients scheduled for non-obstetric procedures, who were randomly distributed in five groups: control (no treatment - C); 2.5 mg droperidol (D); 10 mg nalbuphine (N); association of previous drugs (DN); and 8 mg ondansetron (O). Pruritus was quantitatively evaluated at 30 minutes, 1, 2 and 3 hours after spinal sufentanil.
  
  
  RESULTS
  Groups C and O had significantly higher incidence of itching as compared to groups D, N and DN. However, there has been no significant difference in the need for specific treatment with naloxone among groups.
  
  
  CONCLUSIONS
  Itching prevention in our study, regardless of the drug used, has decreased its severity and has limited the need for specific treatment with naloxone.
authors.affiliation: CET/SBA, FMB, UNESP.
authors.forename: André
authors.initials: A
authors.lastname: Kolm
authors.forename: Alexandre Alberto Fontana
authors.initials: AA
authors.lastname: Ferraz
authors.forename: Norma Sueli Pinheiro
authors.initials: NS
authors.lastname: Módolo
authors.forename: Fábio
authors.initials: F
authors.lastname: Ferrari
authors.forename: Eliana Marisa
authors.initials: EM
authors.lastname: Ganem
authors.forename: Geraldo Rolim
authors.initials: GR
authors.lastname: Rodrigues Júnior
authors.forename: Paulo do
authors.initials: Pd
authors.lastname: Nascimento Júnior
authors.forename: Giane
authors.initials: G
authors.lastname: Nakamura
authors.forename: Lais Helena Camacho
authors.initials: LH
authors.lastname: Navarro
authors.forename: Rodrigo Moreira
authors.initials: RM
authors.lastname: Lima