title: Chemotherapy and biotherapy-induced hypersensitivity reactions.
abstract: Nearly all chemotherapy and biotherapy drugs used in cancer treatment today can cause hypersensitivity reactions. Certain groups of drugs frequently associated with these reactions include the asparaginases, taxanes, platinum compounds, epipodophyllotoxins, and the monoclonal antibodies. Recognizing and managing hypersensitivity reactions are critical when caring for patients receiving these drugs because the reactions are potentially life-threatening. A thorough understanding of the drugs is necessary to assist the nurse in prevention, early recognition, and timely management.
authors.affiliation: BryanLGH Medical Center, 1600 S 48th St, Lincoln, NE 68506, USA.
authors.forename: Ruth
authors.initials: R
authors.lastname: Van Gerpen
mesh_terms: D000707:Anaphylaxis / Q000188:drug therapy*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000276:immunology; D001691:Biological Therapy / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000145:classification / Q000175:diagnosis / Q000451:nursing*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D006967:Hypersensitivity / Q000145:classification / Q000175:diagnosis / Q000209:etiology* / Q000451:nursing*; D054547:National Cancer Institute (U.S.); D014481:United States
chemical_list: D000970:Antineoplastic Agents