New clerodane diterpenoids from Casearia sylvestris.
Two new clerodane diterpenoids 2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide (1) and 15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide (2) and one new nitrogen-containing clerodane diterpenoid 15-oxo-echinophyllin A (3), along with six known compounds, namely, echinophyllin A, (-)-patagonic acid, tyrosol, oplopanone, 4-hydroxy-4-methyl-2-[(1R)-1-(1-methylethyl)-4-oxopentyl]-2-cyclohexen-1-one and 1 beta,6 alpha-dihydroxy-eudesman-4(15)-ene were isolated from the leaves of Casearia sylvestris. Their structures were determined by extensive NMR techniques.
Wang
Wei
W
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, MS 38677, USA.
Ali
Zulfiqar
Z
Li
Xing-Cong
XC
Smillie
Troy A
TA
Guo
De-An
DA
Khan
Ikhlas A
IA
D037821:Casearia / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
C544788:15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide; C544786:2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide; D004224:Diterpenes; D045785:Diterpenes, Clerodane; D010936:Plant Extracts