Dual-rhodamine urea derivative, a novel chemidosimeter for Hg(II) and its application in imaging Hg(II) in living cells.
The synthesis and spectral properties of a chemidosimeter 1,4-di[2-(6-ethylamino-3-ethylimino-2,7-dimethyl-3H-xanthen-9-yl) benzoic acid (aminomethyl)-3-phenylthiourea] benzene (1) for Hg(II) ions are reported, and it has been demonstrated that 1 can be used as a fluorescent probe for monitoring Hg(II) ions in living cells.
Xi
Pin-xian
PX
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, People's Republic of China.
Huang
Liang
L
Liu
Heng
H
Jia
Peng-fei
PF
Chen
Feng-juan
FJ
Xu
Min
M
Zeng
Zheng-zhi
ZZ
D002470:Cell Survival; D002477:Cells / Q000737:chemistry* / Q000166:cytology*; D004785:Environmental Pollutants / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature; D014508:Urea / Q000031:analogs & derivatives* / Q000737:chemistry
C545094:1,4-di(2-(6-ethylamino-3-ethylimino-2,7-dimethyl-3H-xanthen-9-yl)benzoic acid (aminomethyl)-3-phenylthiourea)benzene; D004785:Environmental Pollutants; D005456:Fluorescent Dyes; D012235:Rhodamines; D014508:Urea; D008628:Mercury