title: Nucleophilic heterocyclic carbene catalyzed annulation of enals to chalcones in methanol: a stereoselective synthesis of highly functionalized cyclopentanes.
abstract: Homoenolates generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis undergo annulation with chalcones in methanol to afford methyl beta-hydroxycyclopentanecarboxylates, stereoselectively. Construction of four contiguous stereocenters in a stereoselective manner is noteworthy.
authors.affiliation: Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India. Vijaynair_2001@yahoo.com
authors.forename: Vijay
authors.initials: V
authors.lastname: Nair
authors.forename: Beneesh P
authors.initials: BP
authors.lastname: Babu
authors.forename: Sreekumar
authors.initials: S
authors.lastname: Vellalath
authors.forename: Vimal
authors.initials: V
authors.lastname: Varghese
authors.forename: Anabha E
authors.initials: AE
authors.lastname: Raveendran
authors.forename: Eringathodi
authors.initials: E
authors.lastname: Suresh