title: Seroepidemiology of hepatitis E virus infection in 2-25-year-olds in Sari district, Islamic Republic of Iran.
abstract: The seroprevalence of hepatitis E virus infection (HEV) in children and young adults was determined in a community-based survey in an area of northern Islamic Republic of Iran. Serum samples were taken from 1080 randomly selected apparently healthy 2-25-year-olds from urban and rural regions of Sari district. Anti-HEV IgG antibodies were detected in 25 individuals (2.3%). Seroprevalence increased significantly with age from 3/255 (1.2%) in children < 10 years to 8/110 (7.3%) in those aged 20-25 years. No differences in HEV status were noted between the sexes. Earlier age at exposure to infection and a higher infection rate were found in people residing in rural areas than in urban areas.
authors.affiliation: Department of Paediatrics, Mazandaran University of Medical Sciences, Sari, Islamic Republic of Iran. saffar@softhome.net
authors.forename: M J
authors.initials: MJ
authors.lastname: Saffar
authors.forename: R
authors.initials: R
authors.lastname: Farhadi
authors.forename: A
authors.initials: A
authors.lastname: Ajami
authors.forename: A R
authors.initials: AR
authors.lastname: Khalilian
authors.forename: F
authors.initials: F
authors.lastname: Babamahmodi
authors.forename: H
authors.initials: H
authors.lastname: Saffar
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000914:Antibodies, Viral / Q000097:blood; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D019353:Endemic Diseases / Q000706:statistics & numerical data*; D005260:Female; D016751:Hepatitis E / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D016752:Hepatitis E virus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007492:Iran / Q000453:epidemiology; D008297:Male; D015999:Multivariate Analysis; D011159:Population Surveillance; D012307:Risk Factors; D012423:Rural Health / Q000706:statistics & numerical data; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D012959:Socioeconomic Factors; D014504:Urban Health / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G