Gamma-lactone carbazoles from Clausena anisata.
The study of chemical constituents of the stems of Clausena anisata collected in Thailand led to the isolation and identification of eight known and two new carbazole alkaloids named furanoclausamines A (1) and B (2). Clausamine E (3) was found to exhibit cytotoxicity against the human leukemia cell line HL-60.
Ito
Chihiro
C
Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, Japan.
Itoigawa
Masataka
M
Aizawa
Kie
K
Yoshida
Keisuke
K
Ruangrungsi
Nijsiri
N
Furukawa
Hiroshi
H
D000470:Alkaloids / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D054700:Clausena / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013785:Thailand
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D002227:Carbazoles; D007783:Lactones; C542218:clausamine E; C542217:furanoclausamine A; C542219:furanoclausamine B