title: [Spondylarthropathies].
abstract: Spondylarthropathies include the ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis of inflammatory bowel disease (Crohn disease, ulcerative colitis), some juvenile arthritis and undifferenciated spondylarthropathies. These diseases are linked together by a basic elementary lesion, enthesitis, common clinical and radiological features (sacroiliitis, spondylitis, peripheral arthritis, extra-articular manifestations), and association with HLA B27 antigen. Prevalence of spondylarthropathies in France is estimated at 0.3%, with no difference between women and men. Therapeutic option associate physical therapy and anti-inflammatory drugs. In case of insufficient efficacy of these conventional drugs, TNFalpha antagonist therapy can be used in axial forms, after disease modifying drugs in peripheral forms.
authors.affiliation: Service de rhumatologie, CHU Albert Chenevier-Henri Mondor, AP-HP, UFR Médecine Paris-XII, 94010 Créteil Cedex.
authors.forename: Fernando Kemta
authors.initials: FK
authors.lastname: Lekpa
authors.forename: Valérie
authors.initials: V
authors.lastname: Farrenq
authors.forename: Pascal
authors.initials: P
authors.lastname: Claudepierre
mesh_terms: D006801:Humans; D025242:Spondylarthropathies / Q000175:diagnosis / Q000628:therapy