Efficient use of the Dmab protecting group: applications for the solid-phase synthesis of N-linked glycopeptides.
An efficient protocol for the chemoselective removal of Dmab esters on the solid phase is reported; this method has been successfully utilised for the convergent solid phase synthesis of N-linked glycopeptides.
Conroy
Trent
T
School of Chemistry, The University of Sydney, Sydney, Australia.
Jolliffe
Katrina A
KA
Payne
Richard J
RJ
D000814:Aniline Compounds / Q000737:chemistry*; D001224:Aspartic Acid / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D003512:Cyclohexanones / Q000737:chemistry*; D006020:Glycopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D006834:Hydrazines
D000814:Aniline Compounds; D003512:Cyclohexanones; D006020:Glycopeptides; D006834:Hydrazines; C029424:hydrazine; D001224:Aspartic Acid