title: Safe use of segmental liver grafts from donors after cardiac death (DCD) in children with acute liver failure.
abstract: Emergency liver transplantation is a life-saving procedure in selected subset of children with acute liver failure (ALF), when most recipients receive a segmental graft from a living or heart-beating deceased donor. The increased use of full-liver grafts from donors after cardiac death (DCD) has had a beneficial impact on elective liver transplantation in adults. These grafts however are more susceptible to poor initial function, and most centres are reluctant to consider their use as segmental grafts, let alone in the situation of ALF where good initial function is imperative. In this short article, we describe the use and successful outcome in two children aged 6 weeks and 6 years with acute liver failure who received reduced-size DCD liver grafts.
authors.affiliation: The Liver Unit, Birmingham Children's Hospital, Birmingham, UK.
authors.forename: M Thamara P R
authors.initials: MT
authors.lastname: Perera
authors.forename: Sara
authors.initials: S
authors.lastname: Gozzini
authors.forename: David
authors.initials: D
authors.lastname: Mayer
authors.forename: Khalid
authors.initials: K
authors.lastname: Sharif
authors.forename: James
authors.initials: J
authors.lastname: Bennett
authors.forename: Paolo
authors.initials: P
authors.lastname: Muiesan
authors.forename: Darius F
authors.initials: DF
authors.lastname: Mirza
mesh_terms: D000208:Acute Disease; D002648:Child; D003643:Death; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007223:Infant; D017114:Liver Failure, Acute / Q000628:therapy*; D016031:Liver Transplantation / Q000379:methods*; D014019:Tissue Donors; D016896:Treatment Outcome