title: [Interaction between Actinobacillus pleuropneumoniae RTX toxin and host--a review].
abstract: Actinobacillus pleuropneumoniae (App) is the etiological agent of porcine pleuropneumonia which causes huge economic losses to the pig industry. RTX (repeat in the structural toxin, RTX) is the main virulence-associated factor of the pathogen and, plays a dual role on the pathogen's infection and immunity. Recently research progress is updated in this paper and the necessity and techniques to initiate the pathogen-host interaction study is also raised and discussed. It is believed that the research on the interaction between host and App RTX may further elucidate the pathogen' s molecular pathogenesis.
authors.affiliation: Key laboratory of Preventive Veterinary Medicine of Hubei Province, Veterinary Medicine College, Huazhong Agricultural University, Wuhan 430070, China.
authors.forename: Shengxian
authors.initials: S
authors.lastname: Fan
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.forename: Huanchun
authors.initials: H
authors.lastname: Chen
authors.forename: Qigai
authors.initials: Q
authors.lastname: He
mesh_terms: D016977:Actinobacillus pleuropneumoniae / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D000818:Animals; D001427:Bacterial Toxins / Q000235:genetics / Q000276:immunology*; D054884:Host-Pathogen Interactions; D018410:Pneumonia, Bacterial / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D013553:Swine Diseases / Q000276:immunology* / Q000382:microbiology; D037521:Virulence Factors / Q000276:immunology*
chemical_list: D001427:Bacterial Toxins; D037521:Virulence Factors