title: [Abdominal desmoid tumor: pathologic and therapeutic concepts].
abstract: BACKGROUND
  Abdominal desmoid tumors arise in young adults between 20 and 40 years. They are characterized by a local recurrence in 20 to 30% of cases.
  
  
  OBJECTIVE
  review the clinical and pathologic features of this entity, look for the expression of immunohistochemical markers (actine, desmine, CD34, vimentin) and also to estimate the expression of two potential targets therapy; the hormonal receptors and the CD117.
  
  
  METHODS
  From 1990 to 2004, three cases of abdominal desmoid tumors were diagnosed in the Pathologic laboratory of the Charles Nicole Hospital of Tunis.
  
  
  RESULTS
  The study concerned three women 62, 35 and 30 year-old. All the patients were operated and the size of tumours varied to 5 to 7cm. The CD117 and the hormonal receptors were negative in every case. None of the patients presented local recurrence.
  
  
  CONCLUSIONS
  Abdominal desmoid tumors are locally aggressive but never give metastasis. The negativity of these lesions to the CD117 and in the hormonal receptors does not imply resistance in the hormonal treatment by anti-estrogens.
authors.affiliation: Service d Anatomie Pathologique, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Nadia
authors.initials: N
authors.lastname: Kourda
authors.forename: Sana
authors.initials: S
authors.lastname: Ben Slama
authors.forename: Najoua
authors.initials: N
authors.lastname: Mrabet
authors.forename: Sofien
authors.initials: S
authors.lastname: Sayari
authors.forename: Abdejelil
authors.initials: A
authors.lastname: Zouache
authors.forename: Sarrah Baltagi
authors.initials: SB
authors.lastname: Ben Jilani
authors.forename: Rachida
authors.initials: R
authors.lastname: Zermani
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology* / Q000628:therapy*; D000328:Adult; D005260:Female; D018222:Desmoid Tumors / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies