[Epidemiology of invasive candidiasis in pediatric and adult populations].
BACKGROUND
Invasive candidiasis (IC) is the most frequent fungal disease in children and adults.


OBJECTIVE
To critically review and update the current epidemiology of Candida spp. disease in neonates, children and adults (critically ill patients and in oncohematologic patients and in solid organ transplant recipients).


METHODS
We searched the PubMed/Medline, discussing the current data.


CONCLUSIONS
IC is associated with high attributable morbimortality and increased healthcare costs. In the last decades the incidence of invasive Candida spp. disease has increased in critically ill patients, has decreased in oncohematologic patients, although currently the involvement of non-albicans Candida species in the etiology of this disease is increasing steadily.
Del Palacio
Amalia
A
Servicio de Microbiología, Unidad de Micología, Hospital Universitario 12 de Octubre, Madrid, España. apalacioh.hdoc@salud.madrid.org
Villar
Julia
J
Alhambra
Almudena
A
D000328:Adult; D002177:Candidiasis / Q000453:epidemiology*; D002648:Child; D016638:Critical Illness; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015994:Incidence; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology / Q000382:microbiology; D009369:Neoplasms / Q000150:complications / Q000276:immunology; D009503:Neutropenia / Q000150:complications; D009894:Opportunistic Infections / Q000453:epidemiology* / Q000382:microbiology; D016377:Organ Transplantation; D011183:Postoperative Complications; D011446:Prospective Studies; D012189:Retrospective Studies