Brucellar epididymo-orchitis: review of 53 cases in Babol, northern Iran.
From September 1998 to December 2008, 53 cases of brucellar epididymo-orchitis were treated and followed. The mean age of the patients was 35.5+/-15.9 y. 26 (49.1%) subjects had orchitis. Scrotal pain and swelling, fever, sweating, and arthralgia or arthritis occurred in 53 (100%), 43 (84.3%), 40 (78.4%) and 25 (47.1%) cases, respectively. 16, 20, 9 and 8 cases were treated with gentamicin for 7 d plus doxycycline for 45 d (GD), cotrimoxazole plus doxycycline (CD) for 45 d, streptomycin for 2 weeks and doxycycline (SD) for 45 d, and cotrimaxazole plus rifampin (CR) for 45 d, respectively. We continued the oral agents in all regimens for 2 months in those not clinically cured. At 45 d, cure rates were 48.3%, 65%, 77.8% and 50%, respectively, and at 2 months they were 87.5%, 90%, 100% and 75%, for GD, CD, SD and CR, respectively. In conclusion, scrotal pain and swelling, fever, sweating and arthralgia or arthritis were the main clinical findings in brucellar epididymo-orchitis patients. An aminoglycoside containing combination therapy was usually efficacious. Cotrimoxazole plus doxycycline may be an alternative regimen for those who cannot take an aminoglycoside.
Roushan
Mohammad Reza Hasanjani
MR
Department of Infectious Diseases, Yahyanejad Hospital, Babol Medical University, Babol. hagar2q@yahoo.ca
Baiani
Masomeh
M
Javanian
Mostafa
M
Kasaeian
Ali Akbar
AA
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002002:Brucella / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D004823:Epididymitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009920:Orchitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology; D012307:Risk Factors; D014463:Ultrasonography
D000900:Anti-Bacterial Agents