title: Spinal anesthesia for a cesarean delivery in a woman with type-2M von Willebrand disease: case report and mini-review.
abstract: Von Willebrand disease is the most common inherited bleeding disorder. No consensus exists about the use of neuraxial analgesia or anesthesia in patients with von Willebrand disease. We report on a 38-year-old multiparous woman who presented at 36 weeks' of gestation with spontaneous rupture of membranes for urgent cesarean delivery. Preoperative coagulation tests were normal except for prolonged platelet adhesion and aggregation tests. The cesarean delivery was performed under spinal anesthesia with hyperbaric bupivacaine, fentanyl and morphine sulfate. Desmopressin was administered immediately after delivery. No perioperative complications were observed.
authors.affiliation: Anesthesiology Institute, Cleveland Clinic and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Cata
authors.forename: A
authors.initials: A
authors.lastname: Hanna
authors.forename: J E
authors.initials: JE
authors.lastname: Tetzlaff
authors.forename: A
authors.initials: A
authors.lastname: Bishai
authors.forename: S
authors.initials: S
authors.lastname: Barsoum
mesh_terms: D015667:Acupuncture Analgesia / Q000379:methods*; D000328:Adult; D000775:Anesthesia, Spinal / Q000379:methods*; D001780:Blood Coagulation Tests; D002585:Cesarean Section; D005260:Female; D006470:Hemorrhage / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood; D016896:Treatment Outcome; D014842:von Willebrand Diseases / Q000097:blood / Q000150:complications*