title: Retrograde parotidectomy for pleomorphic adenoma of the parotid gland: a conservative and effective approach.
abstract: To compare the extensiveness and the effectiveness of anterograde and retrograde dissections in superficial parotidectomy for pleomorphic adenoma of the parotid gland, a review of medical records and pathology reports of consecutive patients who underwent superficial parotidectomy has been performed. The sizes of the overall pathologic specimen, the tumor within the specimen, and the normal parotid tissue obtained by anterograde and retrograde approaches have been compared. Mann-Whitney and chi tests have been used to reveal significant differences. Sixty-four patients were included in the study, 32 who underwent anterograde (standard) parotidectomy and 32 who underwent retrograde parotidectomy. Anterograde dissection resulted in a significantly larger size of the overall pathologic specimen as compared with retrograde parotidectomy (P = 0.019). The size of the tumor was nonsignificantly larger for patients undergoing standard parotidectomy (P = 0.174). Patients undergoing anterograde parotidectomy also had a significantly much larger volume of normal tissue removed in the course of extirpating the adenoma, as compared with patients undergoing retrograde parotidectomy (P = 0.008). Despite extracapsular dissection and partial superficial parotidectomy being proposed in the last years as conservative techniques, the optimal treatment of pleomorphic adenoma remains the superficial or total parotidectomy with facial nerve primary identification and preservation. Retrograde parotidectomy, reducing the extent of normal parotid gland removal, may permit a more conservative approach than standard parotidectomy, with the same complication rates and surgical effectiveness.
authors.affiliation: Department of Surgery Pietro Valdoni, Sapienza University of Rome, Rome, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Scarpini
authors.forename: Stefano
authors.initials: S
authors.lastname: Amore Bonapasta
authors.forename: Stefano Amore
authors.initials: SA
authors.lastname: Bonapasta
authors.forename: Mariangela
authors.initials: M
authors.lastname: Ruperto
authors.forename: Annarita
authors.initials: A
authors.lastname: Vestri
authors.forename: Marco
authors.initials: M
authors.lastname: Bononi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Caporale
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology / Q000601:surgery*; D000328:Adult; D004210:Dissection / Q000379:methods; D005154:Facial Nerve / Q000473:pathology; D005158:Facial Paralysis / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D010306:Parotid Gland / Q000294:innervation / Q000473:pathology / Q000601:surgery*; D010307:Parotid Neoplasms / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D020127:Recovery of Function / Q000502:physiology; D012189:Retrospective Studies; D016896:Treatment Outcome