title: Circadian expression of clock genes clock and Cry1 in the embryonic chicken pineal gland.
abstract: Clock and Cry1 expression were examined in the pineal gland of chicken embryos incubated under constant darkness from embryonic day (ED) 0. From ED13, Clock and Cry1 mRNA levels showed episodic alterations. After ED17, circadian pattern of clock gene expression was seen both in vivo and in vitro. Our results support the idea that rhythmic environmental factors are not necessary for the generation of circadian patterns of clock gene expression during development.
authors.affiliation: University of Pécs, Medical School, Department of Anatomy, Pécs, Hungary. andras.d.nagy@aok.pte.hu
authors.forename: Andras D
authors.initials: AD
authors.lastname: Nagy
authors.forename: Siri
authors.initials: S
authors.lastname: Kommedal
authors.forename: Karishma
authors.initials: K
authors.lastname: Seomangal
authors.forename: Valer J
authors.initials: VJ
authors.lastname: Csernus
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D056926:CLOCK Proteins; D002642:Chick Embryo; D005420:Flavoproteins / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D010870:Pineal Gland / Q000196:embryology* / Q000254:growth & development / Q000378:metabolism*; D015534:Trans-Activators / Q000235:genetics*
chemical_list: D005420:Flavoproteins; D015534:Trans-Activators; D056926:CLOCK Proteins