Hyperandrogenism may explain reproductive dysfunction in olympic athletes.
OBJECTIVE
Female athletes are known to be at risk for reproductive dysfunction and osteopenia because of energy deficiency. Although endocrine balance and an optimal body composition are essential for top elite performance, these parameters have not yet been explored fully in Olympic sportswomen. The objective of this study, therefore, was to characterize the menstrual status, body composition, and endocrine balance in female Olympic athletes participating in different disciplines.


METHODS
Ninety Swedish female Olympic athletes underwent a gynecologic examination that included vaginal examination by ultrasound and determination of body composition. In addition, blood samples were collected for the analysis of reproductive hormones and biomarkers of energy availability.


RESULTS
Of all the athletes, 47% were using hormonal contraception (HC). Menstrual dysfunction (MD) was common (27%) among those not using HC and, particularly, in endurance athletes. However, the proportion of body fat and biomarkers of energy availability were within the normal ranges and none exhibited osteopenia. On the contrary, bone mineral density was generally high, particularly in the power athletes. The most common diagnosis associated with MD was polycystic ovary syndrome (PCOS) and not hypothalamic inhibition because of energy deficiency.


CONCLUSIONS
Female Olympic athletes participating in different sports were found to have an anabolic body composition and biomarkers of energy availability within the normal ranges. Most cases of menstrual disturbances observed were due to PCOS. These findings challenge the contemporary concept that reproductive dysfunction in sportswomen is typically a consequence of chronic energy deficiency.
Hagmar
Magnus
M
Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Stockholm, Sweden. magnus.hagmar@karolinska.se
Berglund
Bo
B
Brismar
Kerstin
K
Hirschberg
Angelica Lindén
AL
D000328:Adult; D015415:Biomarkers; D001823:Body Composition; D015519:Bone Density; D017079:Exercise Tolerance; D005260:Female; D053716:Female Athlete Triad Syndrome; D006801:Humans; D011085:Polycystic Ovary Syndrome; D012044:Regression Analysis; D013177:Sports; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
D015415:Biomarkers