title: Blood compatibility improvement of titanium oxide film modified by doping La(2)O(3).
abstract: La(2)O(3) doped titanium oxide (TiO(2)) films with different concentration were deposited by means of the Radio-Frequency magnetron sputtering technique. The microstructure and surface properties of TiO(2) films were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and contact angle test. The blood compatibility of the specimens was evaluated by tests of platelet adhesion. Results show that pure rutile phase is formed in doped samples and La(2)O(3) incorporation significantly improves the wettability and hemocompatibility of TiO(2) films. Our studies demonstrate that La(2)O(3) doped TiO(2) films are potentially useful biomaterials with good blood compatibility.
authors.affiliation: Information College, ZhongKai University of Agriculture and Engineering, Guangzhou 510225, People's Republic of China. lin_phy@163.com
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Dihu
authors.initials: D
authors.lastname: Chen
authors.forename: Keqiang
authors.initials: K
authors.lastname: Wang
authors.forename: Fengmei
authors.initials: F
authors.lastname: Yu
authors.forename: Zhanyun
authors.initials: Z
authors.lastname: Huang
authors.forename: Shirong
authors.initials: S
authors.lastname: Pan
mesh_terms: D001769:Blood / Q000187:drug effects* / Q000378:metabolism; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004526:Efficiency / Q000187:drug effects; D006801:Humans; D007811:Lanthanum / Q000737:chemistry* / Q000494:pharmacology; D008422:Materials Testing; D008567:Membranes, Artificial; D010087:Oxides / Q000737:chemistry* / Q000494:pharmacology; D010973:Platelet Adhesiveness / Q000187:drug effects; D010976:Platelet Count; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D020099:Coated Materials, Biocompatible; D008567:Membranes, Artificial; D010087:Oxides; C009495:titanium dioxide; C103829:lanthanum oxide; D007811:Lanthanum; D014025:Titanium