title: Gamma Knife radiosurgery as a primary treatment option for solitary brain metastases from ovarian carcinoma.
abstract: We present three patients with brain metastasis cases from ovarian carcinoma (BMOC) treated at William Beaumont Hospital with a median follwow-up of 77 months and a mean survival after brain involvement of 23.66 months (range 5-44). Clinical and physical aspects are presented. Between December 2006 and August 2008, three cases of BMOC were treated using Gamma Knife (GK) radiosurgery. All patients had FIGO Stage III primary disease at initial diagnosis. Treatment sequences and features are described. GK achieves excellent local control of BMOC. Other parameters could be considered as biologically effective.
authors.affiliation: Dept. of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan, USA.
authors.forename: A
authors.initials: A
authors.lastname: Navarro-Martín
authors.forename: A
authors.initials: A
authors.lastname: Maitz
authors.forename: M
authors.initials: M
authors.lastname: Manders
authors.forename: E
authors.initials: E
authors.lastname: Ducharme
authors.forename: P
authors.initials: P
authors.lastname: Chen
authors.forename: I
authors.initials: I
authors.lastname: Grills
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery*; D002277:Carcinoma / Q000556:secondary* / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D016634:Radiosurgery