title: Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations.
abstract: Gene sequences from several species representing major vertebrate groups were used to create phylogenetic trees for the growth hormone family of peptide hormones as well as the growth hormone receptor family. These analyses show that both the peptide and receptor families were formed through local duplications in early vertebrate evolution and chromosome duplications.
authors.affiliation: Department of Neuroscience, Uppsala University, Uppsala, Sweden. daniel.ocampo-daza@neuro.uu.se
authors.forename: Daniel
authors.initials: D
authors.lastname: Ocampo Daza
authors.forename: Görel
authors.initials: G
authors.lastname: Sundström
authors.forename: Tomas A
authors.initials: TA
authors.lastname: Larsson
authors.forename: Dan
authors.initials: D
authors.lastname: Larhammar
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000235:genetics; D019143:Evolution, Molecular; D006801:Humans; D010802:Phylogeny; D010907:Pituitary Hormones / Q000145:classification* / Q000235:genetics*; D011003:Ploidies; D014714:Vertebrates / Q000145:classification* / Q000235:genetics*
chemical_list: D010907:Pituitary Hormones