title: Probiotic properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6.
abstract: Exopolysaccharides have prebiotic potential and contribute to the rheology and texture of fermented foods. Here we have analyzed the in vitro bioavailability and immunomodulatory properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6. It resists gastrointestinal stress, adheres to Caco-2 cells, and induces the production of inflammation-related cytokines by polarized macrophages.
authors.affiliation: Centro de Investigaciones Biológicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.
authors.forename: Pilar Fernández
authors.initials: PF
authors.lastname: de Palencia
authors.forename: María Laura
authors.initials: ML
authors.lastname: Werning
authors.forename: Elena
authors.initials: E
authors.lastname: Sierra-Filardi
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Dueñas
authors.forename: Ana
authors.initials: A
authors.lastname: Irastorza
authors.forename: Angel L
authors.initials: AL
authors.lastname: Corbí
authors.forename: Paloma
authors.initials: P
authors.lastname: López
mesh_terms: D001422:Bacterial Adhesion; D018938:Caco-2 Cells; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007155:Immunologic Factors / Q000494:pharmacology*; D008264:Macrophages / Q000276:immunology / Q000382:microbiology; D010376:Pediococcus / Q000276:immunology* / Q000378:metabolism* / Q000502:physiology; D019936:Probiotics / Q000494:pharmacology*; D011509:Proteoglycans; D047071:beta-Glucans / Q000378:metabolism*
chemical_list: D016207:Cytokines; D007155:Immunologic Factors; D011509:Proteoglycans; D047071:beta-Glucans; C010770:polysaccharide-K