title: [Analysis of ocular higher-order aberrations in refractive amblyopia].
abstract: OBJECTIVE
  To compare the distribution of ocular higher-order aberrations in control group and amblyopia group and to explore the mechanism of the higher-order aberrations in refractive amblyopia.
  
  
  METHODS
  The root-mean-square (RMS) values of the higher-order aberrations were measured 3 times across 6.5 mm dilated pupil of 74 eyes using Allegro Wave Analyzer. The results were compared in normal control group and amblyopia group which were determined by the best corrected visual acuity.
  
  
  RESULTS
  RMS4, RMS5, RMS6 and RMSh in amblyopia were all significantly greater than those in control group. RMS values presented a degressive trend from RMS3 to RMS6, and RMS3 was the dominant higher-order aberration in the two groups. Coma and Y-axis coma had significant differences in the two groups.
  
  
  CONCLUSIONS
  The high level of higher-order aberrations is related to amblyopia. Coma, particularly y-axis coma plays an important part in the corrected vision. It suggests that the diagnosis of amblyopia should include ocular higher-order aberrations.
authors.affiliation: Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Feng-juan
authors.initials: FJ
authors.lastname: Yu
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Song
authors.forename: Long-qian
authors.initials: LQ
authors.lastname: Liu
authors.forename: Ying-ping
authors.initials: YP
authors.lastname: Deng
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000550:Amblyopia / Q000175:diagnosis* / Q000209:etiology; D015858:Anisometropia / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008297:Male; D012029:Refraction, Ocular / Q000502:physiology*