title: Caesarean section outcome in eclamptic patients: a comparison of infiltration and general anaesthesia.
abstract: BACKGROUND
  Eclamptic patients undergoing caesarean delivery present extreme management problems for both obstetricians and anaesthetists. These problems reflect a poor maternal and perinatal outcome.
  
  
  OBJECTIVE
  To determine outcomes following the use of infiltrative anaesthesia (gLA) compared with general anaesthesia (gGA) in eclamptic patients undergoing caesarean section.
  
  
  METHODS
  Eclamptic patients scheduled for emergency caesarean section were prospectively studied. They were randomised into two groups to receive either infiltration with local anaesthetic or general anaesthesia for caesarean section. The protocol used for this study included clinical and sociodemographic data, chest examination prior to administration of anaesthesia, maternal and perinatal outcome, duration of maternal hospital stay and intraoperative blood pressure measurement.
  
  
  RESULTS
  There were a total of 76 eclamptic patients in the study. There were no significant differences between the infiltration and general anaesthesia groups with regard to clinical and bio-socio-demographic parameters. Fourteen (40.0%) newborns in the gLA had lowerApgar scores in the first minute than 27 (73.0%) in the gGA group. Five (14.3%) newborns were stillbirths in gLA while 2 (5.4%) were found in the gGA. Twenty-one (60.0%) in gLA had Apgar scores e"8 compared to 10 (27.0%) in the gGA. The duration of hospital stay was longer in the gGA (17.1+/-4.1 days) than the gLA (13.0+/-1.6 days) with a statistically significant difference (p<0.0001). There were five (12.5%) maternal deaths in the gGA and two (5.0%) in the gLA. Intraoperatively, the mean arterial pressure and mean systolic pressure at skin incision were consistently and significantly higher in the gGA group than in gLA group.
  
  
  CONCLUSIONS
  Local infiltrative anaesthesia appears to have a better maternal and perinatal outcome than general anaesthesia for eclamptic patients undergoing caesarean section.
authors.affiliation: Obstetric Anesthesiology Unit, Department of Anesthesiology, Edith Wolfson Medical Centre, 62 Halohamim Street, Holon, Israel. soglonye@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Fyneface-Ogan
authors.forename: S A
authors.initials: SA
authors.lastname: Uzoigwe
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods; D000772:Anesthesia, Local / Q000009:adverse effects / Q000379:methods; D000773:Anesthesia, Obstetrical / Q000379:methods; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D002585:Cesarean Section; D004333:Drug Administration Routes; D004461:Eclampsia; D005260:Female; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D007902:Length of Stay; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous