How to search for specific markers of cancer stem cells.
According to the cancer stem cell hypothesis, cancer stem cells with unlimited self-renewal and multi-differentiation properties such as adult stem cells are the root cause of cancer initiation and progression, and targeted therapy to cancer stem cells is to become the most efficient therapy of cancer. However, specific markers should be discovered to define cancer stem cells accurately before targeted therapy. Therefore, we propose a model of specific markers of cancer stem cells and how to search for such markers.
Liu
Hai Guang
HG
Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, China.
Zhang
Xiao Hua
XH
D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D014411:Neoplastic Stem Cells / Q000737:chemistry / Q000145:classification*
D014408:Biomarkers, Tumor