title: [The relationships between initial clinical features and prognosis in 14 cases of diffuse alveolar hemorrhage syndrome].
abstract: Diffuse pulmonary alveolar hemorrhage (DAH) is caused by various disorders and is a medical emergency that often results in acute respiratory failure requiring prompt diagnosis and aggressive treatment. However, the relationships between the prognosis and the initial clinical feature in DAH remain unclear. We investigated the relationships between initial clinical features and prognosis in 14 cases of DAH. We examined 14 patients with DAH about laboratory data, CT scan findings, treatment and outcome. Three of 14 patients died of acute respiratory failure due to DAH. In the laboratory data on admission, the patients with over 230 IU/L of serum LDH levels had a poor outcome. In pulmonary function data on admission, the patients with under 300 of P/F ratio had poor outcome. On CT scan findings on admission, the patients with consolidation shadows had a poor outcome compared to the patients with ground-glass shadows. In our data, serum LDH concentration, P/F ratio and CT scan findings on admission are important factors in the prognosis of DAH.
authors.affiliation: The Division of Respiratory Medicine and Clinical Allergy, Fujita Health University.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kohashi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Saito
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Totani
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Yoneda
authors.forename: Masamichi
authors.initials: M
authors.lastname: Hayashi
authors.forename: Mitsushi
authors.initials: M
authors.lastname: Okazawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sakakibara
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006470:Hemorrhage / Q000503:physiopathology*; D006801:Humans; D008171:Lung Diseases / Q000401:mortality / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011650:Pulmonary Alveoli; D012131:Respiratory Insufficiency / Q000401:mortality; D013577:Syndrome