title: Vitek2 system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications.
abstract: Qnr determinants have now been found worldwide. In 2008, among 6150 Enterobacteriaceae, 12 isolates belonging to different bacterial species showing an unusual quinolone resistance pattern on Vitek2 system were investigated. Of 12, 11 harbored a qnr gene. Without QRDR modifications, qnr genes can be detected based on a Vitek2 resistance phenotype.
authors.affiliation: Service de Bactériologie-Hygiène hospitalière, CHU de Nantes, 9 quai Moncousu, 44093 Nantes Cedex 01, France. stephane.corvec@chu-nantes.fr
authors.forename: Stéphane
authors.initials: S
authors.lastname: Corvec
authors.forename: Lise
authors.initials: L
authors.lastname: Crémet
authors.forename: Alain
authors.initials: A
authors.lastname: Reynaud
authors.forename: Didier
authors.initials: D
authors.lastname: Lepelletier
authors.forename: Nathalie
authors.initials: N
authors.lastname: Caroff
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000254:growth & development*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015363:Quinolones / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D015363:Quinolones