title: Endoscopic sellar floor reconstruction with concha bullosa bone autograft and nasal septal flap: technical case report.
abstract: BACKGROUND
  A novel method is introduced for sellar floor reconstruction after expanded endoscopic endonasal transsphenoidal surgery using concha bullosa bone autograft and vascularized, posteriorly based flaps of septal mucoperichondrium.
  
  
  METHODS
  A 62-year-old woman presented to her primary care physician with the insidious onset of enlarging hands and feet, coarsening of facial features, and bilateral carpal tunnel syndrome. Endocrine studies revealed elevated growth hormone (22 ng/mL) and somatomedian-C (810 ng/mL) levels. Brain magnetic resonance imaging displayed a 1.2-cm pituitary adenoma. The patient was diagnosed with acromegaly secondary to a pituitary adenoma and underwent expanded endoscopic endonasal transsphenoidal surgery for tumor resection. Preoperatively, the patient was noted to have abnormal right middle turbinate pneumatization (concha bullosa). Following adenoma resection, the sellar floor was reconstructed using concha bullosa bone autograft resected during the endonasal approach. Bilateral vascularized nasoseptal mucosal flaps were then placed over the sellar floor.
  
  
  CONCLUSIONS
  In patients with concha bullosa, conchal bone provides a useful substrate for sellar reconstruction after endoscopic endonasal transsphenoidal surgery.
authors.affiliation: Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14209, USA. afabiano@buff alo.edu
authors.forename: A J
authors.initials: AJ
authors.lastname: Fabiano
authors.forename: N R
authors.initials: NR
authors.lastname: Rigual
authors.forename: C S
authors.initials: CS
authors.lastname: Belber
authors.forename: R A
authors.initials: RA
authors.lastname: Fenstermaker
mesh_terms: D000172:Acromegaly / Q000209:etiology / Q000601:surgery; D000236:Adenoma / Q000473:pathology / Q000601:surgery; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009296:Nasal Cavity / Q000033:anatomy & histology / Q000601:surgery; D009297:Nasal Mucosa / Q000098:blood supply / Q000601:surgery / Q000637:transplantation; D009300:Nasal Septum / Q000601:surgery* / Q000637:transplantation; D019635:Neurosurgical Procedures / Q000379:methods; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods*; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013524:Surgical Flaps; D014182:Transplantation, Autologous / Q000379:methods*; D016896:Treatment Outcome; D014420:Turbinates / Q000601:surgery* / Q000637:transplantation
chemical_list: D013006:Growth Hormone