Combined en bloc liver/pancreas transplantation in two different patients.
Combined en bloc liver/pancreas transplantation (CLPT) was used primarily in the treatment of otherwise non-resectable upper abdominal malignancy. In fact, a more appropriate indication is in patients with liver disease and insulin-dependent diabetes mellitus (IDDM). Here, we report on two successful cases of CLPT at our hospital. One was a patient with non-resectable advanced liver cancer. The recipient survived for 23 mo and finally died of recurrent tumor. The other was a patient with severe biliary complication after orthotopic liver transplantation and preoperative IDDM. We performed CLPT with a modified surgical technique of preserving the native pancreas. He is currently liver-disease- and insulin-free more than 27 mo post-transplant. Based on our experience in two cases of abdominal cluster transplantation, we describe the technical details of CLPT and a modification of the surgical procedure.
Chen
Zhi-Shui
ZS
Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. zschen@tjh.tjmu.edu.cn
Meng
Fan-Ying
FY
Chen
Xiao-Ping
XP
Liu
Dun-Gui
DG
Wei
Lai
L
Jiang
Ji-Pin
JP
Du
Dun-Feng
DF
Zhang
Wei-Jie
WJ
Ming
Chang-Sheng
CS
Gong
Nian-Qiao
NQ
D000328:Adult; D006801:Humans; D008107:Liver Diseases / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000379:methods*