[Detection of cryptosporidium infection among AIDS patients in Guangdong and Yunnan].
OBJECTIVE
To investigate the infection of Cryptosporidium and its epidemiological characteristics in AIDS patients of Southern China.


METHODS
Stool samples colleted from AIDS confirmed patients. The samples were detected for oocyst of Cryptosporidium by acid fast bacteria stain and indirect fluorescent antibody stain respectively, CD4 count was detected by Flow Cytometry.


RESULTS
212 samples of fresh stool obtained from the AIDS patients who live in Guangdong and Yunnan province. The total infection rate of Cryptosporidium in AIDS patients was 4.25% (9/212), the infectious rate of oocyst in the group of 50- 59-years-old was significantly higher than those in 30-39 (P < 0.01); the infectious rate of oocyst in patients with antiretroviral therapy (ART) was also significantly lower (P = 0.0000); we found the patients coinfected with Cryptosporidium with CD4 count all below 100 cells/microl. However, there were no any difference between the infectious rate to the patient's gender, areas and stool shape.


CONCLUSIONS
AIDS patients infected by Cryptosporidium are not rare in southern China, and the infectious rate was lower than western country. Patients received ART could decrease the infectious rate of Cryptosporidium, Cryptosporidium always happen in patient whose CD4 count was very low (< 100 cells/microl).
Le
Xiao-hua
XH
Shenzhen Donghu Hospital, Shenzhen 518020, China.
Wang
Hui
H
Gou
Ji-zhou
JZ
Chen
Xin-chun
XC
Yang
Gui-lin
GL
Yang
Qian-ting
QT
Li
Xiao-he
XH
Zhou
Bo-ping
BP
Li
Hui-qin
HQ
Cai
Wei-ping
WP
D017088:AIDS-Related Opportunistic Infections / Q000469:parasitology*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000469:parasitology*; D000818:Animals; D000953:Antigens, Protozoan; D018791:CD4 Lymphocyte Count; D002681:China; D003457:Cryptosporidiosis / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology / Q000469:parasitology; D003458:Cryptosporidium / Q000737:chemistry / Q000302:isolation & purification*; D005243:Feces / Q000469:parasitology; D005434:Flow Cytometry; D015658:HIV Infections / Q000469:parasitology; D006801:Humans; D033661:Oocysts; D013194:Staining and Labeling
D000953:Antigens, Protozoan