[Hypoxia as the main activator of angiogenesis and fatty tissue growth].
Poor content of oxygen indices gene expression for angiogenic growth factors both in adipocytes and in stromal cells of the fatty tissue. Stimulation of blood vessels by these factors leads to hyperplasia ofpregenitior cells and by their differentiation. This review mentions functional changes occurring in the fatty tissue cells under the effect of hypoxy.
Kalinina
N I
NI
Efimenko
A Iu
AIu
Starostina
E E
EE
Parfenova
E V
EV
Tkachuk
V A
VA
D017667:Adipocytes / Q000378:metabolism*; D000273:Adipose Tissue / Q000254:growth & development / Q000378:metabolism*; D000693:Anaerobiosis; D000818:Animals; D015687:Cell Hypoxia; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D009389:Neovascularization, Pathologic / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D017154:Stromal Cells / Q000378:metabolism
D016207:Cytokines; D010100:Oxygen