Two-stimuli manipulation of a biological motor.
F1-ATPase is an enzyme acting as a rotary nano-motor. During catalysis subunits of this enzyme complex rotate relative to other parts of the enzyme. Here we demonstrate that the combination of two input stimuli causes stop of motor rotation. Application of either individual stimulus did not significantly influence motor motion. These findings may contribute to the development of logic gates using single biological motor molecules.
Ristic
Zorica
Z
Department of Molecular Cell Biology, VU University Amsterdam, Amsterdam, the Netherlands. dirk.bald@falw.vu.nl.
Vitali
Marco
M
Duci
Alessandro
A
Goetze
Christian
C
Kemnitz
Klaus
K
Zuschratter
Werner
W
Lill
Holger
H
Bald
Dirk
D