title: [A case of triple negative chest wall recurrent breast cancer treated with capecitabine and docetaxel combination therapy (XT therapy)].
abstract: A 59-year-old woman underwent modified radical mastectomy for left breast cancer 9 years earlier. This time, a chest wall recurrence was found. A chest CT showed a chest wall tumor and lymph node metastases. PET images showed increased uptake in chest wall tumor and lymph nodes. The serum tumor markers have also elevated. Open biopsy of chest wall tumor was performed, and the tumor was diagnosed as invasive ductal carcinoma[ER(-), Pg R (-), HER2 score(0)]. Combination chemotherapy with capecitabine and docetaxel was initiated. After 7 courses of treatment, a marked response has been seen. Capecitabine and docetaxel combination therapy are considered useful for treatment of triple negative recurrent breast cancer.
authors.affiliation: Breast Care Center, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center.
authors.forename: Yu
authors.initials: Y
authors.lastname: Sawada
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Fujii
authors.forename: Hiroki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Goro
authors.initials: G
authors.lastname: Yokoyama
authors.forename: Roka Namoto
authors.initials: RN
authors.lastname: Matsubayashi
authors.forename: Yuka
authors.initials: Y
authors.lastname: Inoue
authors.forename: Noriko
authors.initials: N
authors.lastname: Uesugi
authors.forename: Seiya
authors.initials: S
authors.lastname: Momosaki
authors.forename: Uhi
authors.initials: U
authors.lastname: Toh
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D000069287:Capecitabine; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077143:Docetaxel; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography; D043823:Taxoids / Q000627:therapeutic use*; D013899:Thoracic Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D035441:Thoracic Wall / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D043823:Taxoids; D003841:Deoxycytidine; D000077143:Docetaxel; D000069287:Capecitabine; D005472:Fluorouracil