Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening.
Many countries have introduced newborn screening for cystic fibrosis to facilitate diagnosis prior to the development of lung disease. Although most infants with cystic fibrosis are asymptomatic from a respiratory point of view at diagnosis, structural lung disease has been detected by computed tomography. We present a case of an asymptomatic infant with cystic fibrosis diagnosed following newborn screening who had endobronchial infection with Pseudomonas aeruginosa and radiological evidence of bronchiectasis at 3 months of age.
Mott
Lauren S
LS
Division of Clinical Sciences, Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, PO Box 855, West Perth, WA, 6872, Australia.
Gangell
Catherine L
CL
Murray
Conor P
CP
Stick
Stephen M
SM
Sly
Peter D
PD
D001987:Bronchiectasis / Q000000981:diagnostic imaging* / Q000209:etiology*; D018893:Bronchoalveolar Lavage; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening; D011552:Pseudomonas Infections / Q000150:complications; D014057:Tomography, X-Ray Computed