Molecular recognition and self-assembly special feature: Squaring cooperative binding circles.
The cooperative binding effects of viologens and pyridines to a synthetic bivalent porphyrin receptor are used as a model system to study how the magnitudes of these effects relate to the experimentally obtained values. The full thermodynamic and kinetic circles concerning both activation and inhibition of the cage of the receptor for the binding of viologens were measured and evaluated. The results strongly emphasize the apparent character of measured binding and rate constants, in which the fractional saturation of receptors with other guests is linearly expressed in these constants. The presented method can be used as a simple tool to better analyze and comprehend the experimentally observed kinetics and thermodynamics of natural and artificial cooperative systems.
Deutman
Alexander B C
AB
Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands.
Monnereau
Cyrille
C
Moalin
Mohamed
M
Coumans
Ruud G E
RG
Veling
Nico
N
Coenen
Michiel
M
Smits
Jan M M
JM
de Gelder
René
R
Elemans
Johannes A A W
JA
Ercolani
Gianfranco
G
Nolte
Roeland J M
RJ
Rowan
Alan E
AE
D001665:Binding Sites; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013816:Thermodynamics; D014755:Viologens / Q000737:chemistry*
D011166:Porphyrins; D011725:Pyridines; D014755:Viologens