title: Supplement value of magnetic resonance imaging in small hepatic lesion (< or = 20 mm) detected on routine computed tomography.
abstract: OBJECTIVE
  To determine the supplemental MRI value in characterization of small hepatic lesions (< or = 20 mm) indetermined by routine CT scan.
  
  
  METHODS
  This was a retrospective study. Sixty-four patients with 81 indeterminate small hepatic lesions on the CT scan were included in this study. Two radiologists simultaneously evaluated the CT scan, followed by MRI. Patient history, imaging record, and final diagnosis were blinded. Final diagnoses were made by interpretation of all medical data and defined these lesions as benign or malignancy by using either histology or follow-up imaging combined with laboratory data.
  
  
  RESULTS
  In 64 patients, 62 lesions (76.5%) of 81 indeterminate lesions were benign, whereas 19 lesions (23.5%) were malignant. MRI interpreted 55 lesions as benign, 17 lesions as malignant, and 9 as indeterminate lesions. If the indeterminate lesions were assumed as benign lesions, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), are 68.4%, 93.6%, 76.5%, and 90.6%, respectively.
  
  
  CONCLUSIONS
  MRI can supplement CT scan in characterization of small hepatic lesion with high specificity and accuracy.
authors.affiliation: Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. rasih@mahidol.ac.th
authors.forename: Sith
authors.initials: S
authors.lastname: Phongkitkarun
authors.forename: Tichakorn
authors.initials: T
authors.lastname: Srianujata
authors.forename: Janjira
authors.initials: J
authors.lastname: Jatchavala
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed