title: An attempt to improve the clinical scale for assessment of haemophilic arthropathy in children.
abstract: Of the methods used to evaluate haemophilic arthropathy, clinical joint score can only detect advanced and not minor changes, which usually occur in younger patients. In addition, the currently used clinical scores are poorly correlated with the MRI and X-rays scales. In an attempt to address these shortcomings, a modification of Stockholm clinical scale was designed in which elements of clinical information were included. This new scale was applied in 165 joints of 40 patients with haemophilia A and B and the results were statistically analyzed for its capacity to detect early joints alterations. Furthermore, the adjusted score was compared with Pettersson's radiological score and Denver's MRI score, which can detect early signs of arthropathy. The adjusted scale (a) revealed the earliest abnormalities of haemophilic arthropathy and its correlation with the Pettersson and Denver scores is better than those of Stockholm's scale, (b) provided prediction of the Denver score and (c) was simple and safe to be performed and it could easily be repeated.
authors.affiliation: Haemophilia Centre, Haemostasis Unit, Aghia Sophia Children's Hospital, Thivon/M. Assias, Goudi, Athens 115 27, Greece. helenpergantou@in.gr
authors.forename: Helen
authors.initials: H
authors.lastname: Pergantou
authors.forename: George
authors.initials: G
authors.lastname: Matsinos
authors.forename: Helen
authors.initials: H
authors.lastname: Platokouki
authors.forename: Andreas
authors.initials: A
authors.lastname: Papadopoulos
authors.forename: Sophie
authors.initials: S
authors.lastname: Aronis
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006467:Hemophilia A / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D002836:Hemophilia B / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D011859:Radiography; D012044:Regression Analysis; D012720:Severity of Illness Index