[Role of enamel matrix proteins in inducing biomimetic mineralization of the enamel: a study with quartz crystal microbalance technique].
OBJECTIVE
To investigate the adsorption behavior of enamel matrix proteins (EMPs) on the enamel surface and study their effect on biomineralization of enamel using quartz crystal microbalance (QCM) technique.


RESULTS
The EMPs were adsorbed on the enamel surface to form a protein film, which was soaked in simulated body fluid solutions. After 30 days of biomimetic mineralization, the hydroxyapatite nucleation, growth and aggregation occurred with hydroxyapatite crystal formation on the enamel surface.


CONCLUSIONS
The EMPs play a key role in regulating enamel mineralization.
Wang
Zhi-wei
ZW
Department of Conservative Dentistry, College of Science and Technology, and Department of Stomatology, First Affiliated Hospital, Jinan University, Guangzhou 510632, China. jnuwzhw@sina.com
Zhao
Yue-ping
YP
Zhou
Chang-ren
CR
Liao
Guo-wei
GW
D000327:Adsorption; D000818:Animals; D003746:Dental Enamel Proteins / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D006882:Hydroxyapatites / Q000032:analysis* / Q000737:chemistry; D011791:Quartz; D051381:Rats; D017207:Rats, Sprague-Dawley; D013499:Surface Properties; D014089:Tooth Remineralization / Q000379:methods*
D003746:Dental Enamel Proteins; D006882:Hydroxyapatites; C109069:enamel matrix proteins; D011791:Quartz