title: Conjugates of boron clusters with derivatives of natural chlorin and bacteriochlorin.
abstract: Conjugates of bacteriochlorin p and chlorin e(6) with cobalt bis(dicarbollide) anion [3,3'-Co(1,2-C(2)B(9)H(11))(2)](-) were synthesized using different synthetic approaches. The boronated bacteriochlorin p was prepared by reaction of bacteriochlorin N-amino cycloimide with, bis(dicarbollide)-based carboxylic acid. The boronated chlorin e(6) conjugates were obtained by both "click reaction" of containing alkyne group chlorine with azide derivative of cobaltacarborane and reaction of chorin-based amines with cyclic oxonium derivative of cobalt bis(dicarbollide).
authors.affiliation: A.N. Nesmeyanov Institute of Organoelement Compounds (INEOS), Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia. bre@ineos.ac.ru
authors.forename: V I
authors.initials: VI
authors.lastname: Bregadze
authors.forename: I B
authors.initials: IB
authors.lastname: Sivaev
authors.forename: I A
authors.initials: IA
authors.lastname: Lobanova
authors.forename: R A
authors.initials: RA
authors.lastname: Titeev
authors.forename: D I
authors.initials: DI
authors.lastname: Brittal
authors.forename: M A
authors.initials: MA
authors.lastname: Grin
authors.forename: A F
authors.initials: AF
authors.lastname: Mironov
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D016754:Boron Neutron Capture Therapy; D006801:Humans; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D010778:Photochemotherapy; D011166:Porphyrins / Q000138:chemical synthesis / Q000737:chemistry; D011838:Radiation-Sensitizing Agents / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D011166:Porphyrins; D011838:Radiation-Sensitizing Agents; C452433:bacteriochlorin; C006969:chlorin