Ruthenium-catalyzed oxidation of alcohols into amides.
The synthesis of secondary amides from primary alcohols and amines has been developed using commercially available [Ru(p-cymene)Cl(2)](2) with bis(diphenylphosphino)butane (dppb) as the catalyst.
Watson
Andrew J A
AJ
Department of Chemistry, University of Bath, Claverton Down, Bath, UK.
Maxwell
Aoife C
AC
Williams
Jonathan M J
JM
D000438:Alcohols / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D012428:Ruthenium / Q000737:chemistry*; D013329:Structure-Activity Relationship
D000438:Alcohols; D000577:Amides; D000588:Amines; D009942:Organometallic Compounds; D012428:Ruthenium