Exceptional sensitivity of metal-aryl bond energies to ortho-fluorine substituents: influence of the metal, the coordination sphere, and the spectator ligands on M-C/H-C bond energy correlations.
DFT calculations are reported of the energetics of C-H oxidative addition of benzene and fluorinated benzenes, Ar(F)H (Ar(F) = C(6)F(n)H(5-n), n = 0-5) at ZrCp(2) (Cp = eta(5)-C(5)H(5)), TaCp(2)H, TaCp(2)Cl, WCp(2), ReCp(CO)(2), ReCp(CO)(PH(3)), ReCp(PH(3))(2), RhCp(PH(3)), RhCp(CO), IrCp(PH(3)), IrCp(CO), Ni(H(2)PCH(2)CH(2)PH(2)), Pt(H(2)PCH(2)CH(2)PH(2)). The change in M-C bond energy of the products fits a linear function of the number of fluorine substituents, with different coefficients corresponding to ortho-, meta-, and para-fluorine. The values of the ortho-coefficient range from 20 to 32 kJ mol(-1), greatly exceeding the values for the meta- and para-coefficients (2.0-4.5 kJ mol(-1)). Similarly, the H-C bond energies of Ar(F)H yield ortho- and para-coefficients of 10.4 and 3.4 kJ mol(-1), respectively, and a negligible meta-coefficient. These results indicate a large increase in the M-C bond energy with ortho-fluorine substitution on the aryl ring. Plots of D(M-C) vs D(H-C) yield slopes R(M-C/H-C) that vary from 1.93 to 3.05 with metal fragment, all in excess of values of 1.1-1.3 reported with other hydrocarbyl groups. Replacement of PH(3) by CO decreases R(M-C/H-C) significantly. For a given ligand set and metals in the same group of the periodic table, the value of R(M-C/H-C) does not increase with the strength of the M-C bond. Calculations of the charge on the aryl ring show that variations in ionicity of the M-C bonds correlate with variations in M-C bond energy. This strengthening of metal-aryl bonds accounts for numerous experimental results that indicate a preference for ortho-fluorine substituents.
Clot
Eric
E
Institut Charles Gerhardt, Université Montpellier 2, CNRS 5253, case courrier 1501, Place E. Bataillon, 34095 Montpellier, France.
Mégret
Claire
C
Eisenstein
Odile
O
Perutz
Robin N
RN
D001554:Benzene / Q000737:chemistry*; D005464:Fluorobenzenes / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry; D013816:Thermodynamics
D005464:Fluorobenzenes; D008024:Ligands; D009942:Organometallic Compounds; D012238:Rhodium; D001554:Benzene