title: Common neural mechanisms for explicit timing in the sub-second range.
abstract: Temporal processing is crucial to many cognitive and motor functions. Comparing different aspects of temporal processing is important for a fundamental understanding of its neural mechanisms. In this study, the neural substrates activated during duration discrimination tasks across different sensory modalities, audition and vision, and sensory structures, empty and filled interval, were examined using event-related functional magnetic resonance imaging (MRI). The supplementary motor area and the basal ganglia are suggested as the common neural substrates for temporal processing across sensory modalities and sensory structures for explicit timing in the subsecond range.
authors.affiliation: Institute of Neuroscience, School of Life Science, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Lynn Y L
authors.initials: LY
authors.lastname: Shih
authors.forename: Wen-Jui
authors.initials: WJ
authors.lastname: Kuo
authors.forename: Tzu-Chen
authors.initials: TC
authors.lastname: Yeh
authors.forename: Ovid J L
authors.initials: OJ
authors.lastname: Tzeng
authors.forename: Jen-Chuen
authors.initials: JC
authors.lastname: Hsieh
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001479:Basal Ganglia / Q000033:anatomy & histology / Q000502:physiology; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology / Q000502:physiology; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology*; D013997:Time Factors; D013998:Time Perception / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult