title: Severe adverse drug reaction to gadobenate dimeglumine.
abstract: A 57-year-old man was admitted to our hospital for evaluation and management of stroke in the setting of an atrial septal defect. Shortly after receiving gadobenate dimeglumine for magnetic resonance imaging of the pelvic vessels, he experienced cardiac arrest from which he was resuscitated. His course was complicated by profound distributive shock. The presumed cause was a severe anaphylactic or anaphylactoid reaction to the gadolinium-based compound that he received.
authors.affiliation: Department of Medicine, Northwestern Memorial Hospital, 251 E. Huron St., Galter Suite 3-150, Chicago, IL 60611, USA. bsinger007@md.northwestern.edu
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Singer
authors.forename: Robert S
authors.initials: RS
authors.lastname: Woodrick
authors.forename: Jennifer B
authors.initials: JB
authors.lastname: Pedicano
mesh_terms: D000707:Anaphylaxis; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects; D006323:Heart Arrest / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008536:Meglumine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000009:adverse effects*; D010388:Pelvis / Q000098:blood supply; D010690:Phlebography / Q000379:methods
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine