[Transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amniotic membrane: case report].
Case report of a patient who developed failure of an allogenic living related conjunctival limbal transplantation in the right eye after an episode of epidemic keratoconjunctivitis. After a few months, she underwent transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amniotic membrane (first case in Brazil). The patient evolved with total corneal epithelialization and improvement of the visual acuity. Three months after the surgery, peripheral superficial neovascularization with worsening of the corneal transparency was observed. The vision remained 0.1 after one year of the transplantation.
Gomes
José Alvaro Pereira
JA
Departamento de Oftalmologia, Universidade Federal de São Paulo, SP, Brasil. japgomes@uol.com.br
Pazos
Henrique Santiago Baltar
HS
Silva
André Berger Emiliano
AB
Cristovam
Priscila Cardoso
PC
Belfort Júnior
Rubens
R
D053687:Adult Stem Cells / Q000637:transplantation*; D000650:Amnion; D018929:Cell Culture Techniques / Q000379:methods; D004847:Epithelial Cells / Q000637:transplantation*; D005260:Female; D006801:Humans; D007637:Keratoconjunctivitis / Q000601:surgery*; D016850:Limbus Corneae / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous; D016896:Treatment Outcome