Occurence and bioactivities of funicone-related compounds.
Studies on production of secondary metabolites by fungi have received a substantial boost lately, particularly with reference to applications of their biological properties in human medicine. Funicones represent a series of related compounds for which there is accumulating evidence supporting their possible use as pharmaceuticals. This paper provides a review on the current status of knowledge on these fungal extrolites, with special reference to aspects concerning their molecular structures and biological activities.
Nicoletti
Rosario
R
Council for Research and Experimentation in Agriculture, C.A.T. Research Unit / Via Vitiello 108, Scafati 84018, Italy.
Manzo
Emiliano
E
Institute of Biomolecular Chemistry, National Research Council / Via Campi Flegrei 34, Pozzuoli 80078, Italy.
Ciavatta
Maria Letizia
ML
Institute of Biomolecular Chemistry, National Research Council / Via Campi Flegrei 34, Pozzuoli 80078, Italy.
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D005658:Fungi / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D010407:Penicillium / Q000378:metabolism; D011753:Pyrones / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D011753:Pyrones