title: Catalyst-free alkylation of sulfinic acids with sulfonamides via sp(3) C-N bond cleavage at room temperature.
abstract: An unprecedented catalyst-free alkylation of sulfinic acids with sulfonamides has been developed via sp(3) C-N bond cleavage at room temperature. In the absence of external catalysts and additives, a wide variety of N-benzylic and N-allylic sulfonamides couple with sulfinic acids to give structurally diversified sulfones in moderate to excellent yields. Furthermore, the reaction of N-(2-acyl)allylic sulfonamides with sulfinic acids provides a convenient access to trisubstituted allyl sulfones with exclusive Z selectivity.
authors.affiliation: Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
authors.forename: Cong-Rong
authors.initials: CR
authors.lastname: Liu
authors.forename: Man-Bo
authors.initials: MB
authors.lastname: Li
authors.forename: Dao-Juan
authors.initials: DJ
authors.lastname: Cheng
authors.forename: Cui-Feng
authors.initials: CF
authors.lastname: Yang
authors.forename: Shi-Kai
authors.initials: SK
authors.lastname: Tian