Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors.
Minkkilä
Anna
A
Department of Pharmaceutical Chemistry, University of Kuopio, 70211 Kuopio, Finland. anna.minkkila@uku.fi
Savinainen
Juha R
JR
Käsnänen
Heikki
H
Xhaard
Henri
H
Nevalainen
Tapio
T
Laitinen
Jarmo T
JT
Poso
Antti
A
Leppänen
Jukka
J
Saario
Susanna M
SM
D000581:Amidohydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000818:Animals; D001549:Benzamides / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D002219:Carbamates / Q000737:chemistry / Q000494:pharmacology; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D006868:Hydrolysis; D051379:Mice; D008994:Monoacylglycerol Lipases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010069:Oxadiazoles / Q000737:chemistry / Q000494:pharmacology; D002787:Sterol Esterase / Q000037:antagonists & inhibitors / Q000378:metabolism; D013329:Structure-Activity Relationship; D000099252:Fatty Acid Amide Hydrolases
D000581:Amidohydrolases; D001549:Benzamides; D002219:Carbamates; D004791:Enzyme Inhibitors; D008994:Monoacylglycerol Lipases; D010069:Oxadiazoles; D002787:Sterol Esterase; D000099252:Fatty Acid Amide Hydrolases; C534918:CAY 10499; C500528:cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester