title: Primary yolk sac tumor of the lung.
abstract: Yolk-sac tumor mimics the yolk sac of the embryo, and the presence of alpha fetoprotein in the tumor cells is highly characteristic. We present an 18-year-old boy with primary pulmonary yolk-sac tumor diagnosed postoperatively. A computed tomographic scan revealed a huge intrathoracic soft tissue mass 20 x 25 cm occupying most of the left hemithorax. Two trials of computed tomographic-guided needle biopsy were nonconclusive. A left upper lobectomy was performed with a complete tumor resection. Postoperatively, the patient's alpha fetoprotein (AFP) was 10,512 IU/mL with gradual decline under chemotherapy. The patient is alive 10 months after surgery and is disease free.
authors.affiliation: Department of Surgery, National Cancer Institute, Cairo, Egypt.
authors.forename: Abdel Rahman M
authors.initials: AR
authors.lastname: Abdel Rahman
authors.forename: Emad N
authors.initials: EN
authors.lastname: Ebied
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Nouh
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Gal
authors.forename: Kamal A
authors.initials: KA
authors.lastname: Mansour
mesh_terms: D000293:Adolescent; D018240:Endodermal Sinus Tumor / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male