title: Interlaboratory comparison of the Doumas bilirubin reference method.
abstract: OBJECTIVE
  To assess the performance of the Doumas bilirubin reference method.
  
  
  METHODS
  Ring trails using pooled patient specimens, a calibrator and human sera enriched with unconjugated bilirubin were analyzed in five laboratories using the Doumas bilirubin reference method.
  
  
  RESULTS
  The coefficient of variation for the linear measurement range between laboratories ranged from 1-3%.
  
  
  CONCLUSIONS
  The Doumas bilirubin reference method is robust and reproducible. Bilirubin results using this method may be used in the development of more accurate and reliable calibrators.
authors.affiliation: Department of Pathology, Medical College of Wisconsin, Milwaukee, USA. slo@mcw.edu
authors.forename: Stanley F
authors.initials: SF
authors.lastname: Lo
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Kytzia
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schumann
authors.forename: Melanie
authors.initials: M
authors.lastname: Swartzentruber
authors.forename: Huib L
authors.initials: HL
authors.lastname: Vader
authors.forename: Friederike
authors.initials: F
authors.lastname: Weber
authors.forename: Basil T
authors.initials: BT
authors.lastname: Doumas
mesh_terms: D001663:Bilirubin / Q000097:blood*; D019411:Clinical Laboratory Techniques / Q000379:methods / Q000592:standards; D005069:Evaluation Studies as Topic; D006801:Humans; D012015:Reference Standards; D012016:Reference Values
chemical_list: D001663:Bilirubin