title: [General anesthesia for cesarean section in a patient with moyamoya disease].
abstract: We described our management of a patient with moyamoya disease who presented for emergency cesarean section. A 29-year-old primigravida (162 cm, 61 kg) who had been diagnosed as having moyamoya disease at age 24, underwent urgent cesarean section at 35 weeks of gestation. Because she was medicated with aspirin, general anesthesia was selected. Anesthesia was induced with thiamylal and was maintained with sevoflurane in air oxygen mixture and fentanyl before delivery. After delivery, anesthesia was maintained with midazolam and fentanyl. Ventilation and depth of anesthesia were adjusted according to the end-tidal carbon dioxide tension and bispectral index, respectively. Hypertension caused by tracheal intubation was successfully prevented by nicardipine, which was ineffective for intraoperative hypertension. On the other hand, landiolol was effective for treating intraoperative hypertension and tachycardia. The cesarean delivery was uneventful and a healthy 2104 g neonate was delivered with Apgar score of 7 and 9 at 1 and 5 min, respectively. Landiolol was effective for treating intraoperative hypertension and tachycardia. Monitoring of depth of anesthesia, blood pressure, and ventilation would be essential for cesarean section under general anesthesia in patients with moyamoya disease.
authors.affiliation: Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, Chuo 409-3898.
authors.forename: Nobumasa
authors.initials: N
authors.lastname: Asano
authors.forename: Tadahiko
authors.initials: T
authors.lastname: Ishiyama
authors.forename: Keiko
authors.initials: K
authors.lastname: Sugihara
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsukawa
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage; D002585:Cesarean Section; D004630:Emergencies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007431:Intraoperative Complications / Q000188:drug therapy; D009025:Morpholines / Q000008:administration & dosage; D009072:Moyamoya Disease / Q000150:complications*; D019990:Perioperative Care; D011247:Pregnancy; D011248:Pregnancy Complications; D013610:Tachycardia / Q000188:drug therapy; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives
chemical_list: D000889:Anti-Arrhythmia Agents; D009025:Morpholines; C077049:landiolol; D014508:Urea