title: The effect of casein phosphopeptide-amorphous calcium phosphate on erosive dentine wear.
abstract: BACKGROUND
  Erosive tooth wear is a growing concern in clinical dentistry. Our aims were to assess the effect of Tooth Mousse (TM) in managing erosive dentine wear in vitro.
  
  
  METHODS
  Opposing enamel and dentine specimens from 36 third molar teeth were worn under a load of 100 N for 75 000 cycles in electromechanical tooth wear machines. In experiment 1, TM was applied continuously at the wear interface and the mean dentine wear rate was compared with those of specimens subjected to continuous application of hydrochloric acid (HCl, pH 3.0) and deionized water (DW, pH 6.1) as lubricants. In experiment 2, specimens were subjected to TM application every 1600 cycles at both pH 3.0 and 6.1, and the mean dentine wear rates were compared with those of specimens worn with continuous application of HCl and DW lubricants.
  
  
  RESULTS
  Dentine wear was reduced significantly with continuous application of TM compared with HCl and DW lubricants. Specimens prepared with continuous TM application displayed smooth wear facets, whereas more pronounced microwear details were observed with HCl and DW lubricants.
  
  
  CONCLUSIONS
  Both remineralization and lubrication seem to contribute to reduction in dentine wear associated with TM application, although lubrication appears to have a more pronounced effect.
authors.affiliation: School of Dentistry, The University of Adelaide, South Australia. sarbin.ranjitkar@adelaide.edu.au
authors.forename: S
authors.initials: S
authors.lastname: Ranjitkar
authors.forename: T
authors.initials: T
authors.lastname: Narayana
authors.forename: J A
authors.initials: JA
authors.lastname: Kaidonis
authors.forename: T E
authors.initials: TE
authors.lastname: Hughes
authors.forename: L C
authors.initials: LC
authors.lastname: Richards
authors.forename: G C
authors.initials: GC
authors.lastname: Townsend
mesh_terms: D002364:Caseins / Q000627:therapeutic use*; D003802:Dentifrices / Q000627:therapeutic use*; D003804:Dentin / Q000187:drug effects* / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D016014:Linear Models; D008963:Molar; D019217:Tooth Attrition / Q000188:drug therapy* / Q000473:pathology; D014089:Tooth Remineralization / Q000379:methods
chemical_list: D002364:Caseins; D003802:Dentifrices; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex