title: [Perioperative antibiotic therapy in newborns according to CDC criteria - preliminary report].
abstract: The aim of the study was elaboration of optimal perioperative antibiotic therapy in neonates according to CDC criteria (Center for Disease Control and Prevention). Classification in 4 groups of infections was carried out in relation to contamination of the surgical wound: clean, clean-contamination, contaminated and dirty. Based on the authors' own experience, CDC criteria were adapted to the contamination of surgical wounds in neonatal surgery. Antibiotic therapy for each of the four groups was also proposed except for the newborns with birth weight below 1500 g. For the neonates with extreme low birth weight (<1500 g) individual treatment based on other risk factors of infection, abnormal bacterial colonization and antibiotics received up to now have to be taken into consideration. Criteria for local and general infection were also defined. We consider that our report concerning rules of antibiotic therapy in neonates requiring surgical treatment will contribute to rational antibiotic administration in this group of patients. Verification of this report should be performed, based on a multicentre study.
authors.affiliation: Klinika Neonatologii i Intensywnej Terapii Noworodka, Instytut Matki i Dziecka, 01-211 Warszawa. magda_rutkowska@poczta.onet.pl
authors.forename: Magdalena
authors.initials: M
authors.lastname: Rutkowska
authors.forename: Ewa
authors.initials: E
authors.lastname: Sawicka
authors.forename: Ludmiła
authors.initials: L
authors.lastname: Bacewicz
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Manowska
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D002487:Centers for Disease Control and Prevention, U.S.; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy* / Q000601:surgery*; D019990:Perioperative Care / Q000379:methods*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014481:United States
chemical_list: D000900:Anti-Bacterial Agents