title: Synthesis of amino acid derivatives of quinolone antibiotics.
abstract: Optically pure conjugates of quinolone antibiotics with naturally occurring amino acids are synthesized in 40-98% yields.
authors.affiliation: Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Munawar Ali
authors.initials: MA
authors.lastname: Munawar
authors.forename: Judit
authors.initials: J
authors.lastname: Kovacs
authors.forename: Levan
authors.initials: L
authors.lastname: Khelashvili
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D002937:Cinoxacin / Q000138:chemical synthesis / Q000737:chemistry; D024841:Fluoroquinolones / Q000138:chemical synthesis / Q000737:chemistry; D009268:Nalidixic Acid / Q000138:chemical synthesis / Q000737:chemistry; D010093:Oxolinic Acid / Q000138:chemical synthesis / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D011804:Quinolines; D014230:Triazoles; D009268:Nalidixic Acid; C012771:benzotriazole; D010093:Oxolinic Acid; D002937:Cinoxacin; C012976:flumequine