title: [Surgical management of solitary eosinophilic granuloma of the calvaria. Two case reports].
abstract: Langerhans cell histiocytosis is a systemic disease resulting from the oligoclonal proliferation of Langerhans cells, occurring most commonly in children and young adults. The focal form of the disease, also known as eosinophilic granuloma, most frequently involves the calvaria. We present two cases of calvarial eosinophilic granulomas that were surgically removed. These tumors are reputed to have an excellent prognosis, even if local recurrences and systemic dissemination can occur during the follow-up. The authors discuss the pathogenesis and the evolutive profile but also the therapeutic management of solitary eosinophilic granuloma of the calvaria.
authors.affiliation: Unité 501, service de neurochirurgie B, hôpital neurologique et neurochirurgical Pierre-Wertheimer, 59, boulevard Pinel, 69677 Bron cedex, France. berhouma.moncef@yahoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Berhouma
authors.forename: W
authors.initials: W
authors.lastname: Krichen
authors.forename: A
authors.initials: A
authors.lastname: Chamseddine
authors.forename: H
authors.initials: H
authors.lastname: Jemel
mesh_terms: D018949:Antigens, CD1 / Q000378:metabolism; D002648:Child; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D019635:Neurosurgical Procedures; D009777:Occipital Bone / Q000000981:diagnostic imaging / Q000601:surgery; D012886:Skull / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D018949:Antigens, CD1