Environmental exposure to asbestos and the exposure-response relationship with mesothelioma.
An epidemiological and environmental study was carried out in Shubra El-Kheima city, greater Cairo, of the exposure-response relationship between asbestos and malignant pleural mesothelioma. Radiological screening was done for 487 people occupationally exposed to asbestos, 2913 environmentally exposed to asbestos and a control group of 979 with no history of exposure. Pleural biopsy was done for suspicious cases. The airborne asbestos fibre concentrations were determined in all areas. There were 88 cases of mesothelioma diagnosed, 87 in the exposed group. The risk of mesothelioma was higher in the environmentally exposed group than other groups, and higher in females than males. The prevalence of mesothelioma increased with increased cumulative exposure to asbestos.
Madkour
M T
MT
Department of Chest Diseases, Faculty of Medicine, Institute of Environmental Studies and Research, Ain Shams University, Cairo, Egypt. ashraf_madkour@yahoo.com
El Bokhary
M S
MS
Awad Allah
H I
HI
Awad
A A
AA
Mahmoud
H F
HF
D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis; D001194:Asbestos / Q000009:adverse effects / Q000032:analysis; D001706:Biopsy; D016022:Case-Control Studies; D004534:Egypt / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis; D004784:Environmental Monitoring / Q000379:methods; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects / Q000032:analysis; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects / Q000032:analysis; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D012111:Residence Characteristics; D012307:Risk Factors; D017678:Sex Distribution; D018709:Statistics, Nonparametric; D014504:Urban Health / Q000706:statistics & numerical data
D000393:Air Pollutants; D001194:Asbestos