title: Functional mapping of the motor cortex of the rat using transdural electrical stimulation.
abstract: Motor cortex stimulation oriented by functional cortical mapping is used mainly for treating otherwise intractable neurological disorders, however, its mechanism of action remains elusive. Herein, we present a new method for functional mapping of the rat motor cortex using non-invasive transdural electrical stimulation. This method allows a non-invasive mapping of the surface of the neocortex providing a differentiation of representative motor areas. This study may facilitate further investigation about the mechanisms mediating the effects of electrical stimulation, possibly benefiting patients who do not respond to this neuromodulation therapy.
authors.affiliation: Teaching and Research Institute, Hospital Sírio-Libanês, São Paulo, SP, Brazil. fonoffet@usp.br
authors.forename: Erich Talamoni
authors.initials: ET
authors.lastname: Fonoff
authors.forename: Jose Francisco
authors.initials: JF
authors.lastname: Pereira
authors.forename: Leonardo Valente
authors.initials: LV
authors.lastname: Camargo
authors.forename: Camila Squarzoni
authors.initials: CS
authors.lastname: Dale
authors.forename: Rosana Lima
authors.initials: RL
authors.lastname: Pagano
authors.forename: Gerson
authors.initials: G
authors.lastname: Ballester
authors.forename: Manoel Jacobsen
authors.initials: MJ
authors.lastname: Teixeira
mesh_terms: D000818:Animals; D001931:Brain Mapping / Q000379:methods*; D004558:Electric Stimulation / Q000379:methods*; D019054:Evoked Potentials, Motor; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar