title: Continuous glucose monitoring in youth with type 1 diabetes.
abstract: Continuous glucose monitoring (CGM) is becoming increasingly popular and represents the third era of diabetes management. Currently available CGM devices have been studied in youth with type 1 diabetes and show similar accuracy across all age groups. Tolerability of these devices relates to alarm settings, sensor skin irritation, and durability of the device. Youth will be most successful on a CGM regimen if they have a personal investment in wearing the CGM device and have a stable support system for their diabetes care. Data indicate that glycemic control improves the most in youth who wear CGM devices >or=5 days per week, allowing for the ability to make more insulin dose changes. CGM has proven useful in alerting youth to hypoglycemia and may be a valuable tool with exercise. Further studies are needed to assess the utility of CGM for prevention of severe hypoglycemic events and increasing time spent in euglycemia. Fear of hypoglycemia may be ameliorated with CGM use; however, the potential for increased stress in families with continuous feedback must also be considered. In the future, CGM use in youth may couple with insulin pump technology to create a "closed-loop" system in which the CGM device will direct insulin administration without user input.
authors.affiliation: Barbara Davis Center for Childhood Diabetes, Aurora, Colorado 80045, USA. Paul.Wadwa@ucdenver.edu
authors.forename: R Paul
authors.initials: RP
authors.lastname: Wadwa
authors.forename: Rosanna
authors.initials: R
authors.lastname: Fiallo-Scharer
authors.forename: Brandon
authors.initials: B
authors.lastname: Vanderwel
authors.forename: Laurel H
authors.initials: LH
authors.lastname: Messer
authors.forename: Erin
authors.initials: E
authors.lastname: Cobry
authors.forename: H Peter
authors.initials: HP
authors.lastname: Chase
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis* / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000523:psychology; D006442:Glycated Hemoglobin / Q000378:metabolism; D006029:Glycosuria / Q000652:urine; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use; D007328:Insulin / Q000009:adverse effects / Q000627:therapeutic use; D018670:Monitoring, Ambulatory / Q000379:methods* / Q000523:psychology
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin