Blood compatibility improvement of titanium oxide film modified by doping La(2)O(3).
La(2)O(3) doped titanium oxide (TiO(2)) films with different concentration were deposited by means of the Radio-Frequency magnetron sputtering technique. The microstructure and surface properties of TiO(2) films were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and contact angle test. The blood compatibility of the specimens was evaluated by tests of platelet adhesion. Results show that pure rutile phase is formed in doped samples and La(2)O(3) incorporation significantly improves the wettability and hemocompatibility of TiO(2) films. Our studies demonstrate that La(2)O(3) doped TiO(2) films are potentially useful biomaterials with good blood compatibility.
Zhang
Lin
L
Information College, ZhongKai University of Agriculture and Engineering, Guangzhou 510225, People's Republic of China. lin_phy@163.com
Chen
Dihu
D
Wang
Keqiang
K
Yu
Fengmei
F
Huang
Zhanyun
Z
Pan
Shirong
S
D001769:Blood / Q000187:drug effects* / Q000378:metabolism; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004526:Efficiency / Q000187:drug effects; D006801:Humans; D007811:Lanthanum / Q000737:chemistry* / Q000494:pharmacology; D008422:Materials Testing; D008567:Membranes, Artificial; D010087:Oxides / Q000737:chemistry* / Q000494:pharmacology; D010973:Platelet Adhesiveness / Q000187:drug effects; D010976:Platelet Count; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology; D014961:X-Ray Diffraction
D020099:Coated Materials, Biocompatible; D008567:Membranes, Artificial; D010087:Oxides; C009495:titanium dioxide; C103829:lanthanum oxide; D007811:Lanthanum; D014025:Titanium