title: Occurence and bioactivities of funicone-related compounds.
abstract: Studies on production of secondary metabolites by fungi have received a substantial boost lately, particularly with reference to applications of their biological properties in human medicine. Funicones represent a series of related compounds for which there is accumulating evidence supporting their possible use as pharmaceuticals. This paper provides a review on the current status of knowledge on these fungal extrolites, with special reference to aspects concerning their molecular structures and biological activities.
authors.affiliation: Council for Research and Experimentation in Agriculture, C.A.T. Research Unit / Via Vitiello 108, Scafati 84018, Italy.
authors.forename: Rosario
authors.initials: R
authors.lastname: Nicoletti
authors.affiliation: Institute of Biomolecular Chemistry, National Research Council / Via Campi Flegrei 34, Pozzuoli 80078, Italy.
authors.forename: Emiliano
authors.initials: E
authors.lastname: Manzo
authors.affiliation: Institute of Biomolecular Chemistry, National Research Council / Via Campi Flegrei 34, Pozzuoli 80078, Italy.
authors.forename: Maria Letizia
authors.initials: ML
authors.lastname: Ciavatta
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D005658:Fungi / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D010407:Penicillium / Q000378:metabolism; D011753:Pyrones / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D011753:Pyrones