Iron-sulfur cluster biosynthesis: role of a semi-conserved histidine.
His mediates iron delivery to the [2Fe-2S] assembly site of ISU/IscU scaffold proteins, but is not required for the binding of iron or cluster.
Huang
Jia
J
Evans Laboratory of Chemistry, The Ohio State University, Columbus, OH 43210, USA.
Cowan
J A
JA
D000595:Amino Acid Sequence; D002942:Circular Dichroism; D006639:Histidine / Q000737:chemistry*; D006801:Humans; D007501:Iron / Q000378:metabolism; D007506:Iron-Sulfur Proteins / Q000096:biosynthesis* / Q000737:chemistry / Q000378:metabolism; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D013056:Spectrophotometry, Ultraviolet
D007506:Iron-Sulfur Proteins; D006639:Histidine; D007501:Iron