title: Cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic syndrome.
abstract: Neurologic symptoms commonly occur in oncology patients, and in some cases they may be the presenting symptom of malignancy. Cancer-related neurologic syndromes are rarely pathognomonic and must be differentiated from other benign or serious conditions. This article reviews common neuro-oncologic syndromes that may lead to urgent evaluation in the emergency department, including cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic neurologic syndromes.
authors.affiliation: Neuro-Oncology, University of Colorado Denver School of Medicine, 12631 E. 17th Avenue, MS# B-185, Aurora, CO 80045, USA. denise.damek@ucdenver.edu
authors.forename: Denise M
authors.initials: DM
authors.lastname: Damek
mesh_terms: D001927:Brain Diseases / Q000209:etiology / Q000628:therapy*; D001929:Brain Edema / Q000209:etiology / Q000628:therapy; D003693:Delirium / Q000209:etiology / Q000628:therapy; D004636:Emergency Service, Hospital; D006801:Humans; D008577:Meningeal Neoplasms / Q000556:secondary; D009369:Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D020361:Paraneoplastic Syndromes, Nervous System / Q000209:etiology / Q000628:therapy; D012640:Seizures / Q000209:etiology / Q000628:therapy; D020521:Stroke / Q000209:etiology / Q000628:therapy