title: Tetra-probe, 24-hour pH monitoring for laryngopharyngeal reflux: a technique for simultaneous study of hypopharynx, oesophagus and stomach.
abstract: OBJECTIVE
  This study aimed to introduce the technique of tetra-probe, 24-hour pH monitoring for laryngopharyngeal reflux disease.
  
  
  METHODS
  Tetra-probe, 24-hour pH monitoring was performed for 30 suspected cases of laryngopharyngeal reflux. The proximal probe was placed in the hypopharynx, just above the upper oesophageal sphincter, the second probe was placed in the middle oesophagus, the third probe was placed a few centimetres above the lower oesophageal sphincter, and the distal probe was placed in the stomach.
  
  
  RESULTS
  As the pH at the four sensor sites could be monitored simultaneously, gastric acid levels and gastroesophageal and laryngopharyngeal reflux could be examined. This pH monitoring technique enabled the pH relationship between the four sensor locations to be well documented, enabling gastric acid levels and patterns of reflux to be assessed. This procedure was also able to be used as a functional examination to evaluate anti-reflux medication efficacy.
  
  
  CONCLUSIONS
  Tetra-probe, 24-hour pH monitoring is a reliable functional examination for laryngopharyngeal reflux.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan. kimisato@oct-net.ne.jp
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Umeno
authors.forename: S
authors.initials: S
authors.lastname: Chitose
authors.forename: T
authors.initials: T
authors.lastname: Nakashima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D050782:Esophageal pH Monitoring / Q000295:instrumentation; D005260:Female; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000175:diagnosis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007013:Hypopharynx / Q000503:physiopathology*; D007818:Laryngeal Diseases / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012016:Reference Values; D015203:Reproducibility of Results