title: [Study on water processing conditions of Realgar].
abstract: OBJECTIVE
  To optimize the water processing (shui-fei) condition of Realgar.
  
  
  METHODS
  The processing conditions were optimized by L9 (3)4 orthogonal design with three factors as water dose, process times and dryness temperature. The content of dissolved arsenic As(III) in Realgar was tested by High Performance Liquid Chromatography-hydride generation on-line coupled with atomic fluorescence spectrometry (HPLC-HG-AFS).
  
  
  RESULTS
  The optimized conditions were 15 times quantity of water, 8 times for processing and dryness temperature of 40 degrees C.
  
  
  CONCLUSIONS
  The method is accurate and effective,which can be used to evaluate the quality of processed products of Realgar.
authors.affiliation: School of Public Health, China Medical University, Shenyang 110001, China. jianghong@mail.cmu.edu.cn
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.forename: Jing-hua
authors.initials: JH
authors.lastname: Ding
authors.forename: Ying-hua
authors.initials: YH
authors.lastname: Zhang
authors.forename: Song-tian
authors.initials: ST
authors.lastname: Shi
authors.forename: Shuang
authors.initials: S
authors.lastname: Gao
authors.forename: Hui-zhi
authors.initials: HZ
authors.lastname: Gong
authors.forename: Gui-fan
authors.initials: GF
authors.lastname: Sun
mesh_terms: D000704:Analysis of Variance; D001152:Arsenicals / Q000737:chemistry* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D011786:Quality Control; D015203:Reproducibility of Results; D013440:Sulfides / Q000737:chemistry* / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D014867:Water
chemical_list: D001152:Arsenicals; D013440:Sulfides; D014867:Water; C058317:arsenic disulfide