Tuning inflammation in tuberculosis: the role of decoy receptors.
Decoy receptors are "silent scavengers" of CC chemokines and cytokines, which play a key role in damping inflammation and tissue damage. In this review we discuss on recent findings demonstrating that these receptors set the balance between antimicrobial resistance, immune activation and inflammatory response in Mycobacterium tuberculosis infection.
Di Liberto
Diana
D
Dipartimento di Biopatologia e Metodologie Biomediche, Università di Palermo, Corso Tukory 211, Palermo 90134, Italy.
Caccamo
Nadia
N
Meraviglia
Serena
S
Guggino
Giuliana
G
La Manna
Marco P
MP
Sireci
Guido
G
Salerno
Alfredo
A
Dieli
Francesco
F
D000818:Animals; D006801:Humans; D007249:Inflammation / Q000276:immunology* / Q000473:pathology*; D051379:Mice; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D018121:Receptors, Cytokine / Q000276:immunology*; D014376:Tuberculosis / Q000276:immunology* / Q000473:pathology*
D018121:Receptors, Cytokine