Probiotic properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6.
Exopolysaccharides have prebiotic potential and contribute to the rheology and texture of fermented foods. Here we have analyzed the in vitro bioavailability and immunomodulatory properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6. It resists gastrointestinal stress, adheres to Caco-2 cells, and induces the production of inflammation-related cytokines by polarized macrophages.
de Palencia
Pilar Fernández
PF
Centro de Investigaciones Biológicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Werning
María Laura
ML
Sierra-Filardi
Elena
E
Dueñas
María Teresa
MT
Irastorza
Ana
A
Corbí
Angel L
AL
López
Paloma
P
D001422:Bacterial Adhesion; D018938:Caco-2 Cells; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007155:Immunologic Factors / Q000494:pharmacology*; D008264:Macrophages / Q000276:immunology / Q000382:microbiology; D010376:Pediococcus / Q000276:immunology* / Q000378:metabolism* / Q000502:physiology; D019936:Probiotics / Q000494:pharmacology*; D011509:Proteoglycans; D047071:beta-Glucans / Q000378:metabolism*
D016207:Cytokines; D007155:Immunologic Factors; D011509:Proteoglycans; D047071:beta-Glucans; C010770:polysaccharide-K