title: Introduction à L'Etude de la Médecine Expérimentale. Surgical revolution. Part I.
abstract: Claude Bernard (1813-1878), the most distinguished French physiologist of the 19th century, made incomparable contributions to the world of medicine of his times and even to ours. Bernard believed in scientific determinism and created the term milieu interieur as a manner to better understand experimental medicine and to present a new way of explaining the function of the living organism. Bernard dealt with innovative developments in the glycogenetic function of the liver, extrahepatic glycogenesis, the role of pancreatic juice in the digestion of fats, vasomotor nervous system discoveries, and other important physiological advances. In 1865, Bernard's most extraordinary book on the philosophy and understanding of experimental medicine appeared. This book represented Bernard's unique contribution to the progress of medical and surgical research. Because of the enormous implications of this work on the advancement of surgical research, which were subsequently applied to clinical surgical practice, we propose that this book created a surgical revolution.
authors.forename: Luis H
authors.initials: LH
authors.lastname: Toledo-Pereyra
mesh_terms: D000818:Animals; D005602:France; D013502:General Surgery / Q000266:history*; D049672:History, 19th Century; D006801:Humans; D010686:Philosophy, Medical / Q000266:history; D010827:Physiology / Q000266:history*; D011173:Portraits as Topic; D014824:Vivisection / Q000266:history