Endoscopic follow-up of cyanoacrylate obliteration of gastric varices.
Bleeding from gastric varices is a life-threatening condition. We report our experience with cyanoacrylate injection. Twenty three patients with portal hypertension and gastric varices underwent intra-variceal injection of a cyanoacrylate/lipiodol solution (1:1). Study endpoint was variceal obliteration. Mean follow-up was 25.3 months. Variceal obliteration was achieved in 87% of patients. Recurrence occurred in one patient (4.3%) and rebleeding in another case (4.3%). Mild abdominal pain was described in 13% of patients. Overall mortality was 21.7% and rebleeding related mortality rate was 4.3%. Our results confirm that cyanoacrylate injection is effective and safe to eradicate gastric varices.
Martins
Fernanda Prata
FP
Universidade Federal de São Paulo, São Paulo, SP, Brazil. fernandaprata@terra.com.br
Macedo
Erika Pereira de
EP
Paulo
Gustavo Andrade de
GA
Nakao
Frank Shigueo
FS
Ardengh
José Celso
JC
Ferrari
Angelo Paulo
AP
D003487:Cyanoacrylates / Q000009:adverse effects / Q000627:therapeutic use*; D004932:Esophageal and Gastric Varices / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D006487:Hemostasis / Q000187:drug effects; D016558:Hemostasis, Endoscopic; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D003487:Cyanoacrylates