Kinetic study of the cetyltrimethylammonium/DNA interaction.
A kinetic study of the interaction of the surfactant cetyltrimethylammonium (CTA(+)) with DNA was carried out in water and in salt (NaCl) solutions. The results can be explained in terms of a reaction mechanism involving two consecutive reversible steps. The first step corresponds to the union/separation of the surfactant with/from the DNA. The second step corresponds to a conformational change of the surfactant/DNA complex. The equilibrium constant, calculated from the forward and reverse rate constants of these steps, agrees with the results of a previous thermodynamic study.
Grueso
E
E
The Department of Physical Chemistry, University of Seville, C/Profesor Garcia Gonzalez s/n, 41012 Seville, Spain.
Roldan
E
E
Sanchez
F
F
D000818:Animals; D002417:Cattle; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D007700:Kinetics; D012965:Sodium Chloride / Q000737:chemistry; D012996:Solutions; D014867:Water / Q000737:chemistry
D002593:Cetrimonium Compounds; D012996:Solutions; D014867:Water; D012965:Sodium Chloride; D004247:DNA; C427203:calf thymus DNA; D000077286:Cetrimonium