Tumor detection and serosal invasion of bladder cancer: role of three-dimensional volumetric reconstructed US.
BACKGROUND
Accurate evaluation of local extent in bladder cancer is important to determine the optimal therapeutic strategy and to predict the outcome of treatment. The purpose of this study is to evaluate the accuracy of 3D volumetric reconstructed US in the assessment of tumor detection and serosal invasion in patients with bladder cancer.


METHODS
A total of 14 patients with findings of bladder cancer determined with the use of cystoscopy was examined with the use of bladder two-dimensional (2D) US and subsequent 3D US. US findings were compared with cystoscopy findings and the pathological stage after a TURB or a radical cystectomy in a double-blinded manner.


RESULTS
The sensitivity of preoperative tumor staging was 67.9% for 2D US and sensitivity was 78.6% for 3D US. 3D US was superior sensitivity than 2D US (P < 0.05). The accuracy for serosal invasion in staging of bladder cancer was demonstrated for 88.9% in 2D US and for 100% in 3D US.


CONCLUSIONS
The accuracy for serosal invasion (T3b) in the staging of bladder cancer was demonstrated for 88.9% in 2D US and for 100% in 3D US. 3D volumetric reconstructed US is a non-invasive and accurate technique for tumor detection of bladder cancer.
Park
Hyun Jeong
HJ
Department of Radiology, Soonchunhyang University Hospital, Seoul, Korea.
Hong
Seong Sook
SS
Kim
Jung Hoon
JH
Kwon
Seok Beom
SB
Kwon
Kui Hyang
KH
Choi
Deuk Lin
DL
Park
Sung Tae
ST
Chang
Yun Woo
YW
Hwang
Jung Hwa
JH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging / Q000379:methods; D012680:Sensitivity and Specificity; D012704:Serous Membrane / Q000473:pathology*; D014463:Ultrasonography; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*