title: Regulation of floral patterning by flowering time genes.
abstract: Floral patterning in Arabidopsis requires activation of floral homeotic genes by the floral meristem identity gene, LEAFY (LFY). Here we show that precise activation of expression of class B and C homeotic genes in floral meristems is regulated by three flowering time genes, SHORT VEGETATIVE PHASE (SVP), SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1), and AGAMOUS-LIKE 24 (AGL24), through direct control of a LFY coregulator, SEPALLATA3 (SEP3). Orchestrated repression of SEP3 by SVP, AGL24, and SOC1 is mediated by recruiting two interacting chromatin regulators, TERMINAL FLOWER 2/LIKE HETEROCHROMATIN PROTEIN 1 and SAP18, a member of SIN3 histone deacetylase complex. Our finding of coordinated regulation of SEP3 by flowering time genes reveals a hitherto unknown genetic pathway that prevents premature differentiation of floral meristems and determines the appropriate timing of floral organ patterning.
authors.affiliation: Department of Biological Sciences and Temasek Life Sciences Laboratory, National University of Singapore, Singapore.
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Wanyan
authors.initials: W
authors.lastname: Xi
authors.forename: Lisha
authors.initials: L
authors.lastname: Shen
authors.forename: Caiping
authors.initials: C
authors.lastname: Tan
authors.forename: Hao
authors.initials: H
authors.lastname: Yu
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D035264:Flowers / Q000235:genetics / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D006655:Histone Deacetylases / Q000378:metabolism; D018398:Homeodomain Proteins / Q000378:metabolism; D026161:MADS Domain Proteins / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D002868:Chromosomal Proteins, Non-Histone; D006655:Histone Deacetylases; D018398:Homeodomain Proteins; D026161:MADS Domain Proteins; D014157:Transcription Factors; C419046:AGL20 protein, Arabidopsis; C478065:AGL24 protein, Arabidopsis; C074747:LFY protein, Arabidopsis; C541032:SAP18 protein, Arabidopsis; C121158:SEP3 protein, Arabidopsis; C407549:SVP protein, Arabidopsis; C477788:At5g17690 protein, Arabidopsis