Fetal intracranial haemorrhage and periventricular leukomalacia after second-trimester intrauterine fetal death in monochorionic twins.
BACKGROUND
Intrauterine fetal death of one twin in a monochorionic pregnancy may be associated with adverse neurologic sequelae in the surviving co-twin.


OBJECTIVE
The aim of this report is to try, through a review of literature, to predict the risk of cerebral impairment in the survivor co-twin and to assess the feasability of neurosonography and magnetic resonance imaging in the prenatal diagnosis of brain damage.


METHODS
We report a case of monochorionic twins complicated by a fetal death at approximately 23 weeks' gestation with pathologically confirmed leukomalacia in the surviving twin. A detailed sonographic evaluation of the intracranial anatomy of the surviving twin was performed. Fetal magnetic resonance imaging was offered as well. The patient opted for termination. Evacuation was performed at 24 weeks, and pathologic evaluation revealed severe cerebral infarction with haemorrhage.


CONCLUSIONS
However difficult, a multidisciplinary prenatal counselling should be performed in order to study the prognosis and to try to prevent cerebral palsy in the surviving co-twin.
Ben Temime
R
R
Department of Obstetrics and Gynecology A, Charles Nicolle Hospital Tunis, Tunisia.
Chechia
Abdellatif
A
Attia
Leila
L
Mrad
M
M
Makhlouf
Taher
T
Koubaa
Abdelhamid
A
D000328:Adult; D001159:Arterio-Arterial Fistula / Q000175:diagnosis; D004200:Diseases in Twins / Q000175:diagnosis; D005240:Feasibility Studies; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000175:diagnosis; D006801:Humans; D020300:Intracranial Hemorrhages / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D018570:Risk Assessment