title: [Proctological surgery: use of a salsobromoiodic gel solution in the post-operative period].
abstract: BACKGROUND
  This study was aimed to demonstrate the advantages and the efficacy of a salsobromoiodic gel solution sponge to use in coloproctology after surgery for the most frequent pathologies of anal canal and of perineal region.
  
  
  METHODS
  The Authors have tested the salsobromoiodic gel solution (Fertomcidina U) in a consecutive series of patients referred to 5 coloproctological centers where they have been submitted to surgery for pathologies of anal canal and of perineal region. A total of 30 patients, 15 with clinico-instrumental diagnosis of III-IV degree haemorrhoids and 15 with diagnosis of chronic anal fissure entered in a clinical follow-up after an out-patient setting or surgery for the respective pathologies. The gel formulation is realized as a salsobromoiodic solution containing salicylic acid and magnesium biphosphate making a strong bactericide and fungicide action applicable on human skin for tissues reparation and their re-epithelization. The experimental treatment was performed on the duration of at least 10 days, with two topic applications.
  
  
  RESULTS
  In 100% of the treated patients, the used gel has determined the prevention of infective complications, favouring a normal re-epithelization of tissue submitted to surgery or affected by previous anal mucosal lesions. The use of gel has not caused irritation and skin damage. No symptom and sign of toxicity were observed.
  
  
  CONCLUSIONS
  The use of salsobromoiodic gel solution has been useful to prevent infections and to contribute to the cicatrisation, healing and re-epithelization of anal mucosal lesions after surgery on a normal outpatients setting. The use of gel formulation resulted easy and satisfactory for the patients affected by the most frequent proctological pathologies which require a surgical treatment.
authors.affiliation: Dipartimenti di Chirurgia Generale e Trapianti d'Organo, Istituto Paride Stefanini, Università degli Studi di Roma, Rome, Italy. fagaj@tin.it
authors.forename: F
authors.initials: F
authors.lastname: Gaj
authors.forename: G
authors.initials: G
authors.lastname: Sportelli
authors.forename: S
authors.initials: S
authors.lastname: Veltri
authors.forename: P
authors.initials: P
authors.lastname: Crispino
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001965:Bromides / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005401:Fissure in Ano / Q000601:surgery*; D005500:Follow-Up Studies; D005782:Gels; D006484:Hemorrhoids / Q000601:surgery*; D006801:Humans; D007454:Iodides / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011349:Proctitis / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001965:Bromides; D005782:Gels; D007454:Iodides