Controlled capture and release of cardiac fibroblasts using peptide-functionalized alginate gels in microfluidic channels.
The utilization of peptide-functionalized hydrogels in combination with a divalent chelator offers an effective methodology for capture and release of cells within microfluidic channels.
Plouffe
Brian D
BD
Department of Chemical Engineering, Northeastern University, Boston, Massachusetts 02115, USA.
Brown
Melissa A
MA
Iyer
Rohin K
RK
Radisic
Milica
M
Murthy
Shashi K
SK
D000464:Alginates / Q000737:chemistry*; D000704:Analysis of Variance; D000818:Animals; D002448:Cell Adhesion; D002478:Cells, Cultured; D004492:Edetic Acid / Q000737:chemistry; D005347:Fibroblasts / Q000166:cytology*; D020100:Hydrogels; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D009206:Myocardium / Q000166:cytology*; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D051381:Rats
D000464:Alginates; D020100:Hydrogels; D009842:Oligopeptides; D004492:Edetic Acid; C046617:arginyl-glycyl-aspartyl-serine