title: Magnetic resonance imaging evaluation of mandibular condyle bone marrow and temporomandibular joint disc signal intensity in anaemia patients.
abstract: OBJECTIVE
  To compare the signal intensity (SI) of mandibular condyle bone marrow (MCBM) and the temporomandibular joint (TMJ) disc in patients with chronic anaemia and healthy subjects, and to investigate the relationships between bone marrow changes, age, types of anaemia and severity of anaemia.
  
  
  METHODS
  MRIs of 18 patients with chronic anaemia were compared with those of 12 healthy subjects. The SI of MCBM and the TMJ disc were quantitatively evaluated. The SI of the grey matter (GM), white matter (WM) and the lateral pterygoid muscle were also investigated. Relationships between age, MCBM and TMJ disc signal-intensities and anaemia severity, and correlations between the groups, were analysed.
  
  
  RESULTS
  The mean MCBM SI was lower in anaemia patients (including both subgroups and also separately) than in healthy subjects (P < 0.05). No statistical significance was found for GM, WM and the muscle SI between the anaemia patients and healthy patient group (P > 0.05). No statistical significance was found between the groups with respect to the anterior band, whereas the mean SI value of the posterior band in the study group was significantly lower than in healthy subjects (P < 0.05). There were no correlations between age and MCBM SI, or between anaemia severity and MCBM SI.
  
  
  CONCLUSIONS
  Anaemia may cause bone marrow alterations without any internal derangement. Patients with chronic anaemia exhibit lower mandibular condyle bone marrow and posterior band SI than healthy subjects.
authors.affiliation: Department of Oral Diagnosis and Radiology, Ankara University, Ankara, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Orhan
authors.forename: C
authors.initials: C
authors.lastname: Delilbasi
authors.forename: Cs
authors.initials: C
authors.lastname: Paksoy
mesh_terms: D000328:Adult; D000367:Age Factors; D000740:Anemia / Q000473:pathology*; D000743:Anemia, Hemolytic / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology*; D016022:Case-Control Studies; D002908:Chronic Disease; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008335:Mandibular Condyle / Q000473:pathology*; D008875:Middle Aged; D019224:Temporomandibular Joint Disc / Q000473:pathology*; D055815:Young Adult
chemical_list: D006454:Hemoglobins