[Gut microbiota, responsible for our body weight?].
Obesity is a multifactorial disease and often considered as an imbalance between energy intake and energy expenditure. However, the gut microbiota could have an impact on the development of excess body weight. According to the type of diet, this black box of the bowel could contribute to modifications of both the caloric extraction and the energy expenditure. The gut microbiota is linked with intermediary metabolism and inflammation, and could be involved in physiopathogenesis of type 1 and 2 diabetes, metabolic syndrome and obesity. Fiber enriched diet and Mediterranean type of diet could induce gut microbiota modifications with consecutive weight loss and improvement of both metabolic syndrome and diabetes.
Pataky
Zoltan
Z
Département de médecine communautaire, HUG, 1211 Genève 14. zoltan.pataky@hcuge.ch
Bobbioni-Harsch
Elisabetta
E
Hadengue
Antoine
A
Carpentier
Anne
A
Golay
Alain
A
D000818:Animals; D015992:Body Mass Index; D001835:Body Weight; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology* / Q000378:metabolism / Q000382:microbiology / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000378:metabolism / Q000382:microbiology / Q000517:prevention & control; D038441:Diet, Mediterranean; D004043:Dietary Fiber; D004195:Disease Models, Animal; D004734:Energy Metabolism; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007422:Intestines / Q000382:microbiology*; D024821:Metabolic Syndrome / Q000209:etiology* / Q000378:metabolism / Q000382:microbiology / Q000517:prevention & control; D051379:Mice; D009765:Obesity / Q000209:etiology* / Q000378:metabolism / Q000382:microbiology* / Q000517:prevention & control; D019936:Probiotics / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors