[Prevention of itching after spinal sufentanil: effects of droperidol, nalbuphine, ondansetron and the association of them.].
OBJECTIVE
Spinal opioids may cause some undesirable effects, the most frequent of which is itching. In spite of its low morbidity rate, itching may cause severe discomfort to patients in addition to prolonging hospital stay. This study aimed at evaluating different therapeutic options to prevent itching after spinal sufentanil.


METHODS
Participated in these study 100 patients scheduled for non-obstetric procedures, who were randomly distributed in five groups: control (no treatment - C); 2.5 mg droperidol (D); 10 mg nalbuphine (N); association of previous drugs (DN); and 8 mg ondansetron (O). Pruritus was quantitatively evaluated at 30 minutes, 1, 2 and 3 hours after spinal sufentanil.


RESULTS
Groups C and O had significantly higher incidence of itching as compared to groups D, N and DN. However, there has been no significant difference in the need for specific treatment with naloxone among groups.


CONCLUSIONS
Itching prevention in our study, regardless of the drug used, has decreased its severity and has limited the need for specific treatment with naloxone.
Kolm
André
A
CET/SBA, FMB, UNESP.
Ferraz
Alexandre Alberto Fontana
AA
Módolo
Norma Sueli Pinheiro
NS
Ferrari
Fábio
F
Ganem
Eliana Marisa
EM
Rodrigues Júnior
Geraldo Rolim
GR
Nascimento Júnior
Paulo do
Pd
Nakamura
Giane
G
Navarro
Lais Helena Camacho
LH
Lima
Rodrigo Moreira
RM