title: Surgical treatment for right colon cancer directly invading the duodenum.
abstract: Right colon carcinoma with duodenal invasion is rare, and optimal management remains controversial. Twenty patients demonstrating right-colon carcinoma directly invading the duodenum presented at the Second Xiangya Hospital between 1990 and 2006. Different surgical management strategies were selected based on duodenal involvement, and patient outcomes were evaluated. There was no perioperative death in this series, but three major complications presented during the perioperative period: one case of duodenal stenosis and two duodenal leaks due to gastric or duodenal drainage. Eight of 13 patients treated by en bloc resection survived more than 3 years, including one 10-year survivor and four 5-year survivors. Of the seven patients treated with palliative resection, no patients survived more than 18 months. In conclusion, duodenal invasion by a right-sided colon carcinoma does not necessarily represent incurable disease. If carefully applied based on the extent of duodenal invasion, active surgical management is very useful for improving patient prognosis without increasing the risks associated with surgery.
authors.affiliation: Department of Geriatrics Surgery, The Second Xiangya Hospital of Center-South University, Changsha, Hunan, PRC. yuanlianwen1971@yahoo.com.cn
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lianwen
authors.forename: Zhou
authors.initials: Z
authors.lastname: Jianping
authors.forename: Shu
authors.initials: S
authors.lastname: Guoshun
authors.forename: Liu
authors.initials: L
authors.lastname: Dongcai
authors.forename: Zhou
authors.initials: Z
authors.lastname: Jiapeng
mesh_terms: D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery*; D004386:Duodenum / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications; D015996:Survival Rate; D016896:Treatment Outcome