title: [SERS spectra of serum from diabetic].
abstract: The SERS spectra were measured from normal and the diabetic serum. In the diabetic serum, the band of amide II shifted to 1 585 cm(-1) and the relative intensity increased 14%, while the relative intensity of 593 cm(-1) which belongs to amide VI reduced 33%. For the protein side chain, the band at 1 368 cm(-1) assigned to the "buried" tryptophan shifted to 1 365 cm(-1) of the "exposed" and the relative intensity reduced 59%. The relative intensity of 635 cm(-1) assigned to the gauche conformation of the C-S decrased 15% and the band at 725 cm(-1) increased 58%. These indicate that the structure of the protein changed in the diabetic serum. The relative intensity at 1 449 cm(-1) assigned to the lipids characteristic increased 58%. The relative intensity of the glucide characteristic at 1 331, 1 099 and 740 cm(-1) increased 35%, 100% and 62%, respectively. So it is indicated that the content of lipids, glucide and protein increased in diabetic. These results may offer a powerful experimental basis for diabetes diagnosis and biochemistry mechanism study.
authors.affiliation: School of Physical Science and Information Technology, Liaocheng University, Liaocheng 252059, China. hongwen411@163.com
authors.forename: Hong-Wen
authors.initials: HW
authors.lastname: Han
authors.forename: Xun-Ling
authors.initials: XL
authors.lastname: Yan
authors.forename: Shu-Feng
authors.initials: SF
authors.lastname: Li
authors.forename: Ge
authors.initials: G
authors.lastname: Ban
authors.forename: Ke
authors.initials: K
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.forename: Yan-Xia
authors.initials: YX
authors.lastname: Bing