A precious metal heist.
Nearly all bacterial pathogens require iron to successfully infect their vertebrate hosts. The host molecule lipocalin-2 exploits this by sequestering bacterial siderophores as a mechanism of protection against infection. Raffatellu et al. (2009) show that Salmonella enterica serotype Typhimurium circumvents this through the production of the modified siderophore salmochelin.
Skaar
Eric P
EP
D004760:Enterocolitis / Q000276:immunology* / Q000382:microbiology; D054884:Host-Pathogen Interactions; D006801:Humans; D054834:Lipocalins / Q000276:immunology*; D011485:Protein Binding; D012480:Salmonella Infections / Q000276:immunology* / Q000382:microbiology; D012486:Salmonella typhimurium / Q000276:immunology*; D017262:Siderophores / Q000276:immunology*
D054834:Lipocalins; D017262:Siderophores