title: A novel method improving motor disturbance in Parkinson disease: application of glycerin poultice to the flexor digitorum profundus in the middle phalanx of the little finger.
abstract: OBJECTIVE
  To investigate whether the application of glycerin poultice to the flexor digitorum profundus in the middle phalanx of the little finger (GFML) improves motor disturbance in Parkinson Disease (PD).
  
  
  METHODS
  Dorsiflexion of the little finger and diameter of the pupil in 22 patients with PD and 23 control subjects was evaluated before and after application of GFML. Motor disturbance in patients with PD was evaluated before and after application of GFML.
  
  
  RESULTS
  The application of GFML increased dorsiflexion of the little finger and constricted the pupil in all subjects, which suggests that application of GFML caused the decreased tension of the flexor digitorum profundus and lowered sympathetic nerve activity. With application of GFML, motor disturbance in patients with PD was improved.
  
  
  CONCLUSIONS
  The application of GFML improves motor disturbance in PD which might be caused by reversing the mechanism of the muscle mechanosensitive reflex.
authors.affiliation: Department of Neurology, Yasuda Clinic, Kyoto, Japan. yuzuru-yasuda@mra.biglobe.ne.jp
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Yasuda
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D001458:Bandages; D005260:Female; D005385:Fingers; D005990:Glycerol / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects*; D009129:Muscle Tonus / Q000187:drug effects; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation*; D016059:Range of Motion, Articular / Q000187:drug effects; D012025:Reflex, Pupillary / Q000187:drug effects; D012997:Solvents / Q000008:administration & dosage*; D013710:Tendons
chemical_list: D012997:Solvents; D005990:Glycerol