title: Caffeine and taurine enhance endurance performance.
abstract: Caffeine enhances endurance performance; however, its effect on accumulated lactate remains unclear. Conversely, taurine, which also enhances endurance performance, decreases accumulated lactate. In this study, the effect of combination of caffeine and taurine on endurance performance was assessed. Mice ran on a treadmill, and the accumulated lactate was measured. In addition, muscle fibers from the gastrocnemius muscle of the mice were stained with ATPase and analyzed. The use of caffeine and taurine over a 2 week period enhanced endurance performance. Moreover, taurine significantly decreased the accumulated concentration of lactate over long running distances. However, the diameter of the cross-sections and ratios of Types I, IIA, and IIB muscle fibers were not affected.
authors.affiliation: Doctoral Program of Sports Medicine, University of Tsukuba, GSCHS, 1-1-1 D507, Tennoudai, Ibaraki, Tsukuba 305-8577, Japan. ima3sytag8sr@md.tsukuba.ac.jp
authors.forename: T F
authors.initials: TF
authors.lastname: Imagawa
authors.forename: I
authors.initials: I
authors.lastname: Hirano
authors.forename: K
authors.initials: K
authors.lastname: Utsuki
authors.forename: M
authors.initials: M
authors.lastname: Horie
authors.forename: A
authors.initials: A
authors.lastname: Naka
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: S
authors.initials: S
authors.lastname: Imagawa
mesh_terms: D000818:Animals; D002110:Caffeine / Q000494:pharmacology*; D000697:Central Nervous System Stimulants / Q000494:pharmacology*; D005080:Exercise Test; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018485:Muscle Fibers, Skeletal / Q000187:drug effects; D010807:Physical Endurance / Q000187:drug effects*; D013654:Taurine / Q000494:pharmacology*
chemical_list: D000697:Central Nervous System Stimulants; D013654:Taurine; D019344:Lactic Acid; D002110:Caffeine