Lichen planus in a case of Good's syndrome (thymoma and immunodeficiency).
Patients with thymoma are mostly investigated for autoimmunity but a few patients may have underlying immunodeficiency that is referred to as Good's syndrome (GS). Cardiothoracic surgeons must always consider this diagnosis when undertaking thymectomy, as immunoglobulin levels can be easily measured and is readily available. The immunodeficiency in GS can be life-threatening and more importantly, it is not reversed by thymectomy. Collaborative care with an Immunologist for these patients is strongly recommended.
Khan
Sujoy
S
Path Links Immunology, Scunthorpe General Hospital, UK. sujoykhan@gmail.com
Campbell
Anne
A
Hunt
Carol
C
Sewell
W A Carrock
WA
D000279:Administration, Cutaneous; D000361:Agammaglobulinemia / Q000209:etiology* / Q000276:immunology; D001624:Betamethasone Valerate / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D010348:Patient Care Team; D012141:Respiratory Tract Infections / Q000209:etiology / Q000276:immunology; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000276:immunology / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000276:immunology / Q000601:surgery; D016896:Treatment Outcome
D005938:Glucocorticoids; D001624:Betamethasone Valerate