title: [A case of adult T-cell leukemia/lymphoma with primary lung cancer].
abstract: METHODS
  A 55-year-old man attended our hospital because of a mass at the above his right eye. Cranial MRI showed an enlarged mass 5cm in diameter with intracranial invasion and metastatic brain tumors. The mass was pathologically diagnosed as adult T-cell leukemia/lymphoma (ATLL) because of a high HTLV-1 antibody titer, and radiation therapy was started. Furthermore, since we noted multiple cervical lymphadenopathy, we performed an additional biopsy, which showed poorly-differentiated adenocarcinoma. The primary lesion was the lungs, with bilateral pleural effusion and lymphangitis carcinomatosis. We diagnosed stage IV primary lung cancer and started chemotherapy. However, he developed dyspnea due to pleural effusion and his performance status gradually decreased to 3. Fifteen days after readmission to hospital, he manifested sudden respiratory failure and shock, and died the next day. Autopsy showed ATLL and extensive lung cancer with multiple metastases. There was invasion of ATLL in systemic lymph nodes, which coincided with invasion of adenocarcinoma.
  
  
  CONCLUSIONS
  We encountered a rare case of ATLL and primary lung cancer. Accumulation of cases and further investigations are awaited.
authors.affiliation: Department of Respiratory Medicine, Tokyo Saiseikai Central Hospital.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Miyahara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Itou
authors.forename: Ayumi
authors.initials: A
authors.lastname: Sekine
authors.forename: Daisuke
authors.initials: D
authors.lastname: Taniyama
authors.forename: Tomoko
authors.initials: T
authors.lastname: Katsui
authors.forename: Wakae
authors.initials: W
authors.lastname: Tanaka
authors.forename: Ryouta
authors.initials: R
authors.lastname: Satou
authors.forename: Ako
authors.initials: A
authors.lastname: Kurihara
authors.forename: Yurika
authors.initials: Y
authors.lastname: Satou
authors.forename: Fumio
authors.initials: F
authors.lastname: Sakamaki
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary