title: Synthesis of functionalized indenes via cascade reaction of aziridines and propargyl alcohols.
abstract: A concise synthesis of functionalized indenes via the Lewis acid catalyzed cascade reaction of aziridines and propargylic alcohols has been developed. The methodology offers great potential for the synthesis of biologically active indene derivatives and related polycyclic compounds.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China.
authors.forename: Shaoyin
authors.initials: S
authors.lastname: Wang
authors.forename: Yuanxun
authors.initials: Y
authors.lastname: Zhu
authors.forename: Yanguang
authors.initials: Y
authors.lastname: Wang
authors.forename: Ping
authors.initials: P
authors.lastname: Lu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D000480:Alkynes; D001388:Aziridines; D007192:Indenes; D011083:Polycyclic Compounds; D020005:Propanols; C028255:propargyl alcohol