Lipophagy: selective catabolism designed for lipids.
Until recently, degradation of lipid droplets (LDs) has been thought to take place in the cytosol by resident lipases. In a recent issue of Nature, Singh and coworkers describe the involvement of selective autophagy in the delivery of lipid droplets for lysosomal degradation.
Weidberg
Hilla
H
Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.
Shvets
Elena
E
Elazar
Zvulun
Z
D000818:Animals; D001343:Autophagy; D003600:Cytosol / Q000378:metabolism; D008066:Lipolysis; D008247:Lysosomes / Q000378:metabolism; D051379:Mice