Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis.
The highly specific molecule recognition properties of molecular beacons (MB) are combined with the unique optical properties of gold nanoparticles (Au-NPs) for the development of a dry-reagent strip-type nucleic acid biosensor (DSNAB) that enables sensitive and low-cost detection of nucleic acid samples within 15 min.
Mao
Xun
X
Laboratory of Molecular Diagnostics, Guangzhou Institute of Biomedicine and Health, Chinese academy of Sciences, Guangzhou, Guangdong, 510663, China.
Xu
Hui
H
Zeng
Qingxiang
Q
Zeng
Lingwen
L
Liu
Guodong
G
D015374:Biosensing Techniques; D015342:DNA Probes; D006046:Gold / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry*; D053768:Metal Nanoparticles
D015342:DNA Probes; D007202:Indicators and Reagents; D006046:Gold