title: A meta-analysis of design- and manufacturing-related parameters influencing the wear behavior of metal-on-metal hip joint replacements.
abstract: This article aims to clarify the influence of design- and manufacturing-related parameters on wear of metal-on-metal (MoM) joint bearings. A database search for publications on wear simulator studies of MoM bearings was performed. The results of published studies were normalized; groups with individual parameters were defined and analyzed statistically. Fifty-six investigations studying a total of 200 implants were included in the analysis. Clearance, head size, carbon content, and manufacturing method were analyzed as parameters influencing MoM wear. This meta-analysis revealed a strong influence of clearance on running-in wear for implants of 36-mm diameter and an increase in steady-state wear of heat treated components.
authors.affiliation: Laboratory of Biomechanics, Department of Orthopaedics, University of Heidelberg, Heidelberg, Germany.
authors.forename: Jan Philippe
authors.initials: JP
authors.lastname: Kretzer
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Kleinhans
authors.forename: Eike
authors.initials: E
authors.lastname: Jakubowitz
authors.forename: Marc
authors.initials: M
authors.lastname: Thomsen
authors.forename: Christian
authors.initials: C
authors.lastname: Heisel
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation*; D019544:Equipment Failure Analysis; D006622:Hip Prosthesis / Q000592:standards*; D006358:Hot Temperature; D006801:Humans; D008422:Materials Testing / Q000379:methods; D008670:Metals; D011475:Prosthesis Failure; D013314:Stress, Mechanical
chemical_list: D008670:Metals