HIV latency: present knowledge, future directions.
Current therapies do not eradicate HIV from infected patients. Indeed, HIV hides in a latent form insensitive to these therapies. Thus, one priority is to purge these latent reservoirs. But what mechanisms are responsible for latency and what are the reservoirs of latently infected cells? The present knowledge in terms of HIV latency is still incomplete and current therapeutic strategies fail to eradicate completely latently infected cells. What could the future bring?
Contreras
Xavier
X
University of California San Francisco, 533 Parnassus avenue, Room U432, 94143, San Francisco, CA, USA.
Lenasi
Tina
T
Peterlin
B Matija
BM