title: [Inferon clinicoimmunological efficacy in chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  To study efficacy of leukocytic interferon--inferon in combined treatment of patients with chronic obstructive pulmonary disease (COPD).
  
  
  METHODS
  The trial included 57 COPD patients (mean age 61.2 +/- 1.04 years). Of them, 29 patients received standard treatment (antibiotics, broncholytics, mucolytics). Inferon was added to standard treatment of 28 patients.
  
  
  RESULTS
  Standard treatment alone was not highly effective in COPD patients as the symptoms often persisted and immune status was deficient. Adjuvant inferon activated immunity and raised efficacy of COPD therapy.
  
  
  CONCLUSIONS
  Inferon enhanced immunity in COPD patients and improved treatment results.
authors.forename: U R
authors.initials: UR
authors.lastname: Farkhutdinov
authors.forename: Sh U
authors.initials: ShU
authors.lastname: Farkhutdinov
authors.forename: L M
authors.initials: LM
authors.lastname: Abdrakhmanova
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000276:immunology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D016898:Interferon-alpha / Q000008:administration & dosage / Q000627:therapeutic use*; D016131:Lymphocyte Subsets / Q000276:immunology / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D016896:Treatment Outcome
chemical_list: D007136:Immunoglobulins; D007155:Immunologic Factors; D016898:Interferon-alpha