[Introduction of a MR-compatible system for extracorporal perfusion of vital organs for MR-guided procedures--first-experiences].
OBJECTIVE
To represent a MRI-compatible perfusion-system for extracorporeal perfusion of vital organs which permits the realisation of realistic experiments in a MR scanner.


METHODS
We performed MR examinations of explanted porcine livers and MR-guided interventions in porcine livers. Explanted organs were hemo-perfused under physiological conditions during the experiments. MR-sequences for diagnostic and interventional examinations were used.


RESULTS
The evaluated system was MRI-compatible. The achieved image quality of the used sequences showed excellent anatomical resolution. Planned experiments can be carried out with relatively low expenditure. Diagnostic as well as interventional investigations can be carried out. The used organs showed a stable function within physiological parameters up to 4 hours.


CONCLUSIONS
It is possible to perform ex vivo experiments under in vivo conditions with this system. With the used MR-compatible system MR-guided experimental interventions and thermal ablations can be carried out in explanted organs under in vivo conditions.
Gaffke
Gunnar
G
Universitätsklinikum Magdeburg, Klinik für Radiologie und Nuklearmedizin, Leipziger Strasse 44, 39120 Magdeburg, Germany. gunnar.gaffke@med.ovgu.de
Nagel
Stefan
S
Hegemann
Olaf
O
Speck
Ulrich
U
Grosse-Siestrup
Christian
C
Jungnickel
Kerstin
K
Stroszczynski
Christian
C
D000715:Anatomy / Q000379:methods*; D000818:Animals; D003287:Contrast Media; D005260:Female; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009336:Necrosis; D010477:Perfusion / Q000379:methods; D011859:Radiography; D013552:Swine
D003287:Contrast Media