title: Partial cricotracheal resection for congenital subglottic stenosis in children: the effect of concomitant anomalies.
abstract: OBJECTIVE
  To review the surgical outcomes of partial cricotracheal resection in children with severe congenital subglottic stenosis and define the effect of concomitant anomalies or syndromes affecting outcome.
  
  
  METHODS
  Forty-one children with subglottic stenosis of congenital and mixed (acquired on congenital) etiologies who underwent partial cricotracheal resection were identified from a prospectively collected database. Children with congenital subglottic stenosis and concomitant anomalies/syndromes were compared to children with congenital subglottic stenosis with no syndromes or concomitant anomalies. Operation-specific decannulation rates and complication rates were the primary outcome measures. We performed a two-sample test of proportion using the STATA-10 software for categorical variables to detect differences in proportions. Significance was set at p value<0.05.
  
  
  RESULTS
  Twenty-seven (66%) of 41 children had concomitant anomalies/syndromes and 14 (34%) had congenital subglottic stenosis without concomitant anomalies/syndromes. Four patients needed revision surgery in the concomitant anomaly group and two patients needed revision surgery in the non concomitant anomaly group before achieving decannulation. The operation-specific decannulation rate in the concomitant anomaly group was 85% and 86% in the non anomaly group. When compared to children without concomitant anomaly, children with concomitant anomalies were more likely to have delayed decannulation following partial cricotracheal resection. However, this difference was not found to be statistically significant. The complication and operation-specific decannulation rates after partial cricotracheal resection were comparable to children without concomitant anomalies. Mortality rate was 11% (three of 27 patients) in the group with associated congenital anomalies or syndromes. Two patients succumbed to the primary pathology and one patient died due to tracheostomy-tube obstruction. There was no post-operative death in the non anomaly group.
  
  
  CONCLUSIONS
  Partial cricotracheal resection can be done safely and effectively in children with concomitant anomalies/syndromes to achieve decannulation. The post-operative course may be prolonged but the decannulation and the complication rates are comparable to those children with congenital subglottic stenosis without concomitant anomalies.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, University Hospital (CHUV), Lausanne, Vaud, Switzerland 1011, Switzerland.
authors.forename: Mercy
authors.initials: M
authors.lastname: George
authors.forename: Christos
authors.initials: C
authors.lastname: Ikonomidis
authors.forename: Yves
authors.initials: Y
authors.lastname: Jaquet
authors.forename: Philippe
authors.initials: P
authors.lastname: Monnier
mesh_terms: D000015:Abnormalities, Multiple / Q000601:surgery*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003413:Cricoid Cartilage / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007828:Laryngoscopy; D007829:Laryngostenosis / Q000601:surgery*; D007830:Larynx / Q000002:abnormalities / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014132:Trachea / Q000601:surgery; D016896:Treatment Outcome