Effect of vitamin D supplementation in the institutionalized elderly.
An intervention study with vitamin D supplementation was conducted in order to study the amount of vitamin D required in the elderly. Sixty-four institutionalized elderly were randomly assigned to two groups: group (A) to take a beverage containing 200 mg calcium daily, and group (B) to take a beverage containing 200 mg calcium and 5 microg vitamin D daily for 30 days. Prior to the study, the subjects' average vitamin D intake was 7.3 microg/day, which is approximately 150% of the current adequate intake (AI), however their mean plasma 25 OH-D level at baseline was only 12 ng/mL, strongly indicating hypovitaminosis D. During the study, average plasma 25 OH-D concentration significantly increased to 14.7 ng/mL in group (B), but not in group (A). However, group (B) was still in the hypovitaminosis range. Thus, daily intake exceeding the current AI of 5 microg is required for the institutionalized elderly.
Himeno
Masako
M
Department of Food and Nutrition, Kyoto Women's University, Kyoto 605-8501, Japan.
Tsugawa
Naoko
N
Kuwabara
Akiko
A
Fujii
Minori
M
Kawai
Nobuko
N
Kato
Yuzuru
Y
Kihara
Noriko
N
Toyoda
Tomoko
T
Kishimoto
Masami
M
Ogawa
Yoko
Y
Kido
Shoko
S
Noike
Toshiaki
T
Okano
Toshio
T
Tanaka
Kiyoshi
K
D000368:Aged; D000369:Aged, 80 and over; D002118:Calcium / Q000627:therapeutic use; D019587:Dietary Supplements; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D008297:Male; D009735:Nursing Homes; D009748:Nutrition Disorders / Q000175:diagnosis* / Q000628:therapy; D052756:Nutritional Sciences; D010281:Parathyroid Hormone / Q000097:blood; D013997:Time Factors; D014807:Vitamin D / Q000097:blood / Q000627:therapeutic use*; D014815:Vitamins / Q000627:therapeutic use*
D010281:Parathyroid Hormone; D014815:Vitamins; D014807:Vitamin D; D002118:Calcium