title: The anterolateral thigh free flap for skull base reconstruction.
abstract: OBJECTIVE
  To assess outcomes of patients undergoing reconstruction after resection of skull base tumors with the anterolateral thigh (ALT) free flap.
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  Thirty-four consecutive patients with cancers involving the skull base that underwent reconstruction with the ALT free flap between 2005 and 2008 were reviewed.
  
  
  RESULTS
  The ALT free flap was successfully used to reconstruct two, five, and 17 anterior, lateral, and posterior skull base defects, respectively. In addition, six and four combined anterior-lateral and lateral-posterior defects, respectively, were reconstructed. The overall complication rate was 29 percent. There were no flap losses. Nerve grafts (n = 6) and fascial slings (n = 14) for facial reanimation were performed using the lateral femoral cutaneous nerve and fascia lata from the same donor site as the ALT free flap. By harvesting the flap and graft(s) simultaneously with the resection, an average of 3.0 hours per case was saved.
  
  
  CONCLUSIONS
  The ALT free flap is a versatile, reliable flap that should be considered a first-line option for skull base reconstruction. Operative time is minimized by performing a simultaneous two-team approach to resection and reconstruction, and by harvesting nerve, vein, and fascial grafts from the same donor site as the flap.
authors.affiliation: Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. mhanasono@mdanderson.org
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Hanasono
authors.forename: Justin M
authors.initials: JM
authors.lastname: Sacks
authors.forename: Neha
authors.initials: N
authors.lastname: Goel
authors.forename: Martina
authors.initials: M
authors.lastname: Ayad
authors.forename: Roman J
authors.initials: RJ
authors.lastname: Skoracki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D019292:Skull Base Neoplasms / Q000601:surgery*; D013524:Surgical Flaps; D013848:Thigh / Q000098:blood supply / Q000294:innervation / Q000601:surgery*; D016896:Treatment Outcome