Collagenous fibroma (desmoplastic fibroblastoma) of the lacrimal gland.
A 53-year-old woman presented with mild right upper eyelid edema without erythema or tenderness. Postcontrast, fat-suppressed, T1-weighted MR images demonstrated a slightly enlarged, mildly enhancing right lacrimal gland, with an internal zone of hypointensity. Histopathologic examination showed scattered spindled to stellate fibroblasts within a myxocollagenous matrix. Cells were immunohistochemically positive for vimentin and negative for smooth muscle actin, desmin, S-100 protein, CD34, cytokeratin, and epithelial membrane antigen. To our knowledge, this is the first report of collagenous fibroma involving the orbit.
Ahn
Min
M
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226-4812, USA.
Osipov
Vladimir
V
Harris
Gerald J
GJ
D005134:Eye Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D005260:Female; D018220:Fibroma, Desmoplastic / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged