title: Treatment results with debridement and retention of infected hip prostheses.
abstract: A retrospective systematic review of the management of a periprosthetic joint infection (PJI) cohort of 78 cases was conducted at a single-centre, middle-sized Norwegian hospital from 1997 to 2007. We analysed 40 cases that were managed by surgical debridement with hip prosthesis retention followed by long-lasting pathogen-directed antibiotic therapy. A follow-up time of 58 to 510 weeks free from PJI relapse occurred in 27 of 40 PJI cases (67.5%). The need for a more advanced secondary orthopaedic procedure was recognized in 13 cases. The pathogen responsible for PJI was recovered in only 80% of cases, hence 20% were managed as culture-negative PJI. In cases without prior hip infection or hip surgery, success rate reached 96.3%. Multiple risk factors were found in most cases undergoing PJI relapse. Debridement with hip prosthesis retention should be restricted to only current management guidelines.
authors.affiliation: Department of Medicine, Sørlandet Hospital, Kristiansand, Norway. bwa@live.no
authors.forename: Bjørn
authors.initials: B
authors.lastname: Waagsbø
authors.forename: Anders
authors.initials: A
authors.lastname: Sundøy
authors.forename: Tore M L
authors.initials: TM
authors.lastname: Martinsen
authors.forename: Linn Såve
authors.initials: LS
authors.lastname: Nymo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D015331:Cohort Studies; D003646:Debridement; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D009664:Norway; D017410:Practice Guidelines as Topic; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents