title: Comparative epidemiology of stroke and acute myocardial infarction: the Dijon Vascular project (Diva).
abstract: BACKGROUND
  Despite a common pathophysiological mechanism (ie, atherosclerosis) and similar vascular risk factors, few reliable studies have compared the epidemiology of stroke and acute myocardial infarction (AMI).
  
  
  METHODS
  All first ever cases of stroke and AMI in Dijon, France (151 846 inhabitants) from 2001 to 2006 were prospectively recorded. The 30 day case fatality rates (CFRs) and vascular risk factors were assessed in both groups.
  
  
  RESULTS
  Over the 6 years, 1660 events (1020 strokes and 640 AMI) were recorded. Crude incidence of stroke was higher than that of AMI (112 vs 70.2/100 000/year; p<0.001). With regard to sex, the relative incidence of stroke compared with AMI was 0.88 (95% CI 0.60 to 1.29; p = 0.51) in women <65 years and 2.32 (95% CI 1.95 to 2.75; p<0.001) in those >65 years whereas it was 0.60 (95% CI 0.42 to 0.86; p<0.001) in men below 55 years, 1.01 (0.81 to 1.24, p = 0.96) in those between 55 and 75 years and 2.01 (95% CI 1.48 to 2.71; p<0.001) at 75 years and older. CFRs at 30 days were similar for stroke and AMI (9.80% vs 9.84%; p = 0.5). Hyperglycaemia (>7.8 mmol/l) at onset was significantly associated with higher CFR in both stroke and AMI patients. The prevalence of male sex, hypercholesterolaemia and diabetes was higher in AMI patients whereas hypertension was more frequent in stroke patients.
  
  
  CONCLUSIONS
  These findings will help health care authorities to evaluate future needs for stroke and AMI services, and to develop secondary prevention strategies.
authors.affiliation: The Dijon Stroke Registry (EA 4184), University of Burgundy, University Hospital and Faculty of Medicine of Dijon, Dijon, France.
authors.forename: A
authors.initials: A
authors.lastname: Gentil
authors.forename: Y
authors.initials: Y
authors.lastname: Béjot
authors.forename: L
authors.initials: L
authors.lastname: Lorgis
authors.forename: J
authors.initials: J
authors.lastname: Durier
authors.forename: M
authors.initials: M
authors.lastname: Zeller
authors.forename: G-V
authors.initials: GV
authors.lastname: Osseby
authors.forename: G
authors.initials: G
authors.lastname: Dentan
authors.forename: J-C
authors.initials: JC
authors.lastname: Beer
authors.forename: T
authors.initials: T
authors.lastname: Moreau
authors.forename: M
authors.initials: M
authors.lastname: Giroud
authors.forename: Y
authors.initials: Y
authors.lastname: Cottin
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006943:Hyperglycemia / Q000453:epidemiology; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality; D012042:Registries; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000145:classification / Q000453:epidemiology* / Q000401:mortality