title: Experimental analysis of silicone leakage.
abstract: We analyzed whether gel bleed, the leakage of silicone gel from breast implants, occurs in the human body. We simulated the phenomenon with olive oil. Silicone breast implants were submerged in olive oil, and the concentration of silicone polymers in the olive oil was measured periodically with nuclear magnetic resonance spectroscopy. We found no increase in the silicone concentration. However, clinical conditions might not be adequately simulated because of the shortness of the experimental period and the lack of external stress. However, when clinical experiences and our data are considered, we think that silicone implant durability is an important factor to prevent leakage or gel bleeding.
authors.affiliation: Department of Plastic, Reconstructive and Regenerative Surgery, Graduate School of Medicine, Nippon Medical School Hospital, Japan. chin@peach.plala.or.jp
authors.forename: Takafumi
authors.initials: T
authors.lastname: Chin
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kobe
authors.forename: Hiko
authors.initials: H
authors.lastname: Hyakusoku
authors.forename: Kyoko
authors.initials: K
authors.lastname: Uekusa
authors.forename: Keiko
authors.initials: K
authors.lastname: Hirakawa
authors.forename: Youkichi
authors.initials: Y
authors.lastname: Ohno
mesh_terms: D018427:Breast Implants; D009682:Magnetic Resonance Spectroscopy; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012826:Silicone Elastomers; D020034:Silicone Gels
chemical_list: D012826:Silicone Elastomers; D020034:Silicone Gels