Abnormal cytogenetics in orbital lipoma.
Orbital lipoma is a rare entity with only a small number of cases previously described. The authors describe a case of orbital lipoma in a 56-year-old man, which was treated with surgical excision. Cytogenetic analysis of the lesion demonstrated abnormalities of chromosome 12, consistent with chromosomal abnormalities in lipomas found elsewhere in the body. Therefore, cytogenetic analysis may be useful to differentiate lipomatous tumors from normal orbital fat.
Ong
Lorraine Y
LY
Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. lorraine.ong@gmail.com
Mercer
Bruce
B
Campbell
Lynda J
LJ
McNab
Alan A
AA
D002869:Chromosome Aberrations; D002881:Chromosomes, Human, Pair 12; D020732:Cytogenetic Analysis; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008067:Lipoma / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D014057:Tomography, X-Ray Computed