title: Combined en bloc liver/pancreas transplantation in two different patients.
abstract: Combined en bloc liver/pancreas transplantation (CLPT) was used primarily in the treatment of otherwise non-resectable upper abdominal malignancy. In fact, a more appropriate indication is in patients with liver disease and insulin-dependent diabetes mellitus (IDDM). Here, we report on two successful cases of CLPT at our hospital. One was a patient with non-resectable advanced liver cancer. The recipient survived for 23 mo and finally died of recurrent tumor. The other was a patient with severe biliary complication after orthotopic liver transplantation and preoperative IDDM. We performed CLPT with a modified surgical technique of preserving the native pancreas. He is currently liver-disease- and insulin-free more than 27 mo post-transplant. Based on our experience in two cases of abdominal cluster transplantation, we describe the technical details of CLPT and a modification of the surgical procedure.
authors.affiliation: Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. zschen@tjh.tjmu.edu.cn
authors.forename: Zhi-Shui
authors.initials: ZS
authors.lastname: Chen
authors.forename: Fan-Ying
authors.initials: FY
authors.lastname: Meng
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Chen
authors.forename: Dun-Gui
authors.initials: DG
authors.lastname: Liu
authors.forename: Lai
authors.initials: L
authors.lastname: Wei
authors.forename: Ji-Pin
authors.initials: JP
authors.lastname: Jiang
authors.forename: Dun-Feng
authors.initials: DF
authors.lastname: Du
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Ming
authors.forename: Nian-Qiao
authors.initials: NQ
authors.lastname: Gong
mesh_terms: D000328:Adult; D006801:Humans; D008107:Liver Diseases / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000379:methods*