Phototherapy, photodynamic therapy and lasers in the treatment of acne.
Modern acne therapy uses anticomedogenic, antimicrobial, antiinflammatory,and antiandrogenic substances. As an additional approach in recent years, treatments have been developed based on the application of electromagnetic radiation. Visible light or infrared wave lengths are utilized by most techniques, including blue light lamps, intense pulsed light, photodynamic therapy and lasers. This review evaluates the various methods with regard to efficacy and their current role in the management of acne. Although UV radiation has been frequently used to treat acne, it is now regarded as obsolete due to the unfavorable risk-benefit ratio. Visible light, especially of blue wavelengths, appears to be suitable for the treatment of mild to moderate inflammatory acne. Photodynamic therapy is effective, but, due to considerable immediate side effects, it is best reserved for selected situations. Despite promising observations, intense pulsed light and lasers have to be evaluated in further studies, before they can be recommended.
Degitz
Klaus
K
Department of Dermatology, Ludwig-Maximilian University, Pasinger Bahnhofsplatz 1, Munich, Germany. klaus.degitz@lrz.uni-muenchen.de
D000152:Acne Vulgaris / Q000628:therapy*; D003880:Dermatology / Q000639:trends*; D005858:Germany; D006801:Humans; D010778:Photochemotherapy / Q000379:methods* / Q000639:trends*; D010789:Phototherapy / Q000379:methods* / Q000639:trends*