title: Expression of Cry2 in the chicken pineal gland: effects of changes in light-dark conditions.
abstract: Pineal expression of Cry2 mRNA has been examined in chickens under normal (LD) and reversed (DL) light-dark conditions. In vivo the peak of Cry2 mRNA content at late subjective day under LD diminished after switching to a DL schedule. In vitro, Cry2 mRNA levels showed a steady decrease during light exposure at subjective night. Our data show that light-sensitive clock components in the pinealocytes may be involved in the repression of Cry2 transcription at night, which may contribute to resetting the phase of the clock within 24 h.
authors.affiliation: University of Pécs, Medical School, Department of Anatomy, Pécs, Hungary. andras.d.nagy@aok.pte.hu
authors.forename: Andras D
authors.initials: AD
authors.lastname: Nagy
authors.forename: Karishma
authors.initials: K
authors.lastname: Seomangal
authors.forename: Siri
authors.initials: S
authors.lastname: Kommedal
authors.forename: Valer J
authors.initials: VJ
authors.lastname: Csernus
mesh_terms: D000818:Animals; D002645:Chickens / Q000235:genetics*; D002940:Circadian Rhythm / Q000235:genetics*; D005420:Flavoproteins / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics*; D008027:Light; D010870:Pineal Gland / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D005420:Flavoproteins; D012333:RNA, Messenger