title: Metastatic Merkel cell carcinoma with positive expression of thyroid transcription factor-1--a case report.
abstract: We report on a case of metastatic Merkel cell carcinoma in a 74-year-old patient with positive staining for thyroid transcription factor-1. This represents a new immunohistochemical staining pattern for Merkel cell carcinoma and has implications regarding the accurate diagnosis of this tumor type.
authors.affiliation: St. Andrew's Centre for Plastic Surgery, Broomfield Hospital, Chelmsford, Essex, United Kingdom. adamsiera@yahoo.co.uk
authors.forename: Adam
authors.initials: A
authors.lastname: Sierakowski
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Janabi
authors.forename: Helena van
authors.initials: Hv
authors.lastname: Dam
authors.forename: Manu
authors.initials: M
authors.lastname: Sood
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D015266:Carcinoma, Merkel Cell / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009687:Nuclear Proteins / Q000378:metabolism*; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology*; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; C000614412:NKX2-1 protein, human; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors