Iron-catalyzed amidation of alkynyl bromides: a facile route for the preparation of ynamides.
A facile route to obtain ynamides in high yields was described. The products were achieved through the iron-catalyzed C-N coupling reaction of amides with alkynyl bromides in the presence of 20 mol % of N,N'-dimethylethane-1,2-diamine (DMEDA).
Yao
Bangben
B
Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.
Liang
Zunjun
Z
Niu
Tianmin
T
Zhang
Yuhong
Y