title: Electroencephalographic analysis for the assessment of hepatic encephalopathy: comparison of non-parametric and parametric spectral estimation techniques.
abstract: OBJECTIVE
  To compare electroencephalographic spectral analysis obtained by periodogram (calculated by means of Fast Fourier Transform) and autoregressive (AR) modelling for the assessment of hepatic encephalopathy.
  
  
  METHODS
  The mean dominant frequency (MDF) and the relative power of delta, theta, alpha, and beta bands were computed by both techniques from the electroencephalograms (EEG) of 201 cirrhotics and were evaluated in the clinical and prognostic assessment of the patients.
  
  
  RESULTS
  The values of all the five indexes computed by periodogram and AR modelling matched each other, but the latter provided stable values after the analysis of fewer epochs. Independently of the technique, the relative power of theta and alpha bands fitted the clinical data and had prognostic value. The relative power of beta and delta bands computed by AR modelling fitted more closely with clinical data fitted the clinical data more closely.
  
  
  CONCLUSIONS
  The electroencephalographic spectral indexes obtained by periodogram and AR modelling were found to be, on average, undistinguishable, but the latter appeared less sensitive to noise and provided a more reliable assessment of low-power bands.
authors.affiliation: Clinical Medicine 5, University of Padova, Padova, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Amodio
authors.forename: R
authors.initials: R
authors.lastname: Orsato
authors.forename: P
authors.initials: P
authors.lastname: Marchetti
authors.forename: S
authors.initials: S
authors.lastname: Schiff
authors.forename: C
authors.initials: C
authors.lastname: Poci
authors.forename: P
authors.initials: P
authors.lastname: Angeli
authors.forename: A
authors.initials: A
authors.lastname: Gatta
authors.forename: G
authors.initials: G
authors.lastname: Sparacino
authors.forename: G M
authors.initials: GM
authors.lastname: Toffolo
mesh_terms: D000328:Adult; D000465:Algorithms; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D005583:Fourier Analysis; D006501:Hepatic Encephalopathy / Q000097:blood / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index; D013057:Spectrum Analysis; D018709:Statistics, Nonparametric