title: Techniques of interventional tumor therapy.
abstract: BACKGROUND
  The last few years have seen the rapid development of new image-guided interventions for the local treatment of malignant tumors. The goal of this article is to provide an overview of the techniques that are most commonly used today in interventional oncology.
  
  
  METHODS
  Selective literature review on the current state of image-guided interventional techniques for local tumor therapy.
  
  
  RESULTS
  While surgery, radiation oncology, and systemic chemotherapy are still the three main pillars of tumor therapy, a broad range of minimally invasive, image-guided techniques for local tumor treatment is now available. These may be categorized as percutaneous injection of a toxic substance, transarterial embolization, thermal ablation, and internal radiotherapy. The choice of treatment depends on the type, location, and size of tumor. The greatest amount of clinical experience to date has been gathered in the treatment of primary and secondary hepatic malignancy, but there are interventional treatment options for virtually all regions of the body. At present, the utility of this form of treatment is limited for very large or multiple tumors; novel therapeutic options for these situations are now being studied.
  
  
  CONCLUSIONS
  The outcome of treatment depends on a judicious determination of the indication for it. The indication should be established by interdisciplinary consensus after all treatment options have been considered.
authors.affiliation: Klinik für radiologische Diagnostik, Universitätsklinikum der RWTH Aachen. mahnken@rad.rwth-aachen.de
authors.forename: Andreas H
authors.initials: AH
authors.lastname: Mahnken
authors.forename: Philipp
authors.initials: P
authors.lastname: Bruners
authors.forename: Rolf W
authors.initials: RW
authors.lastname: Günther