title: Socioeconomic status and telomere length: the West of Scotland Coronary Prevention Study.
abstract: BACKGROUND
  It has been hypothesised that socioeconomically deprived people age more rapidly than their more advantaged counterparts and this is biologically manifest in shorter telomeres. However, in the very few studies conducted, substantial uncertainty exists regarding this relationship.
  
  
  METHODS
  In the present investigation, 1542 men in the West of Scotland Coronary Prevention Study responded to a series of enquiries about their socioeconomic position (educational attainment, employment status, area-based deprivation), had their physical stature measured (a proxy for early life social circumstances) and provided a blood specimen from which leucocyte DNA was extracted and telomere length derived.
  
  
  RESULTS
  There was no strong evidence that any of these four indices of socioeconomic position was robustly related to telomere length. The only exception was employment status: men who reported being out of work had significantly shorter telomeres than those who were employed (p = 0.007).
  
  
  CONCLUSIONS
  In this cross-sectional study-the largest to date to examine the relationship-we found little evidence of an association between socioeconomic status and telomere length.
authors.affiliation: MRC Social and Public Health Sciences Unit, University of Glasgow, 4 Lilybank Gardens, Glasgow G12 8RZ, UK. david-b@sphsu.mrc.ac.uk
authors.forename: G D
authors.initials: GD
authors.lastname: Batty
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: S W
authors.initials: SW
authors.lastname: Brouilette
authors.forename: P
authors.initials: P
authors.lastname: Shiels
authors.forename: C
authors.initials: C
authors.lastname: Packard
authors.forename: J
authors.initials: J
authors.lastname: Moore
authors.forename: N J
authors.initials: NJ
authors.lastname: Samani
authors.forename: I
authors.initials: I
authors.lastname: Ford
mesh_terms: D000375:Aging / Q000235:genetics*; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000235:genetics*; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D004651:Employment / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*; D012307:Risk Factors; D012606:Scotland / Q000453:epidemiology; D012923:Social Class; D016615:Telomere / Q000235:genetics*