Gold-Speckled Multimodal Nanoparticles for Noninvasive Bioimaging.
Multimodal Gold-speckled silica nanoparticles as contrast agents for noninvasive imaging with magnetic resonance imaging and photoacoustic tomography have been prepared in a simple one-pot synthesis using nonionic microemulsions. Magnetic resonance contrast is provided through gadolinium incorporated in the silica matrix, whereas the photoacoustic signal originates from nonuniform, discontinuous gold nanodomains speckled across the silica surface.
Sharma
Parvesh
P
Materials Science and Engineering and Particle Engineering Research Center, Molecular Genetics and Microbiology, Biomedical Engineering, Physiology and Functional Genomics, and Department of Surgery, University of Florida, P.O. Box 116135 Gainesville, Florida 32611, and NanoScience Technology Center, Chemistry and Biomolecular Science Center, University of Central Florida, Orlando, Florida 32826.
Brown
Scott C
SC
Bengtsson
Niclas
N
Zhang
Qizhi
Q
Walter
Glenn A
GA
Grobmyer
Stephen R
SR
Santra
Swadeshmukul
S
Jiang
Huabei
H
Scott
Edward W
EW
Moudgil
Brij M
BM