Mammalian epididymal proteome.
In all mammalian species, the final differentiation of the male germ cell occurs in the epididymal duct where the spermatozoa develop the ability to be motile and fertilize an ovum. Understanding of these biological processes is the key to understanding and controlling male fertility. Comparative studies between several mammals could be an informative approach to finding common sperm modifications which are not species-specific. The new global biological approaches such as transcriptomes and proteomes provide considerable information which can be used for such comparative approaches. This report summarizes our proteomic studies of the epididymis of several mammals, including humans.
Dacheux
Jean-Louis
JL
INRA-CNRS 6175, Nouzilly, France. jdacheux@tours.inra.fr
Belleannée
Clémence
C
Jones
Russell
R
Labas
Valérie
V
Belghazi
Maya
M
Guyonnet
Benoît
B
Druart
Xavier
X
Gatti
Jean Luc
JL
Dacheux
Françoise
F
D000818:Animals; D001826:Body Fluids / Q000378:metabolism; D004822:Epididymis / Q000378:metabolism*; D006801:Humans; D008297:Male; D008322:Mammals / Q000378:metabolism*; D020543:Proteome / Q000378:metabolism*; D013045:Species Specificity; D013079:Sperm Maturation
D020543:Proteome