title: Short communication: Milk fat globule membrane as a potential delivery system for liposoluble nutrients.
abstract: A soft physical process was used to extract and purified bovine milk fat globule membrane (MFGM) fractions on a pilot scale. Oil-in-water emulsions enriched with alpha-tocopherol and lycopene were then prepared and stabilized with the extracted MFGM fraction and conventional milk protein concentrates (i.e., whey proteins, caseinate). A protocol of in vitro digestion was set up to evaluate the bioaccessibility of the tocopherol and lycopene in the different emulsions. Bioaccessibility was defined as the capacity of liposoluble compounds to be transferred into mixed micelles formed during the digestion process. Results showed that the accumulation of the tocopherol and lycopene into mixed micelles in MFGM-stabilized emulsions was around 2-fold greater than in emulsions stabilized with conventional milk proteins. This result confirms the potential use of MFGM-enriched ingredients as delivery systems of liposoluble nutrients in food formulations.
authors.affiliation: Nestlé Research Center, Department of Food Science and Technology, Lausanne, Switzerland. jean-baptiste.bezelgues@rdls.nestle.com
authors.forename: J-B
authors.initials: JB
authors.lastname: Bezelgues
authors.forename: F
authors.initials: F
authors.lastname: Morgan
authors.forename: G
authors.initials: G
authors.lastname: Palomo
authors.forename: L
authors.initials: L
authors.lastname: Crosset-Perrotin
authors.forename: P
authors.initials: P
authors.lastname: Ducret
mesh_terms: D002338:Carotenoids / Q000008:administration & dosage / Q000032:analysis; D004655:Emulsions / Q000737:chemistry; D005524:Food Technology / Q000379:methods*; D006017:Glycolipids; D006023:Glycoproteins; D066292:Lipid Droplets; D000077276:Lycopene; D008566:Membranes / Q000737:chemistry*; D008894:Milk Proteins / Q000737:chemistry; D010316:Particle Size; D014677:Pharmaceutical Vehicles / Q000737:chemistry / Q000592:standards*; D024505:Tocopherols / Q000008:administration & dosage / Q000032:analysis
chemical_list: D004655:Emulsions; D006017:Glycolipids; D006023:Glycoproteins; D008894:Milk Proteins; D014677:Pharmaceutical Vehicles; C110367:milk fat globule; D002338:Carotenoids; D024505:Tocopherols; D000077276:Lycopene