title: Left ventricular performance in aortic valve replacement.
abstract: We analyzed the mid-term left ventricular (LV) performance after aortic valve replacement (AVR). We measured LV contractility (end-systolic elastance: Ees), afterload (effective arterial elastance: Ea) and efficiency (ventriculoarterial coupling: Ea/Ees; ratio of stroke work and pressure-volume area: SW/PVA) based on transthoracic echocardiography data obtained before, after and approximately 1 year after isolated AVR in 263 patients with aortic stenosis (AS group; n=116), aortic regurgitation (AR group; n=93) or aortic stenosis and regurgitation (ASR group; n=54). The LV volume was calculated by the Teichholz M-mode method. Ees and Ea were approximated as follows: Ees=mean blood pressure/minimal LV volume; Ea=systolic blood pressure/(maximal LV volume-minimal LV volume). Thereafter, Ea/Ees and SW/PVA were calculated. Arterial blood pressure was measured using manchette methods. Ees and Ea decreased after AVR in the AS group, but increased in the AR group. Ea/Ees and SW/PVA worsened after AVR in the AR group, but improved during a 1-year period after AVR in all groups. Contrasting effects of AVR on LV contractility and afterload between AS and AR were clearly demonstrated. The mid-term LV contractility and efficiency after AVR were excellent and satisfactory. However, LV efficiency worsened early after AVR in AR patients.
authors.affiliation: Department of Cardiovascular Surgery, Kyushu University, Fukuoka 812-8582, Japan. tanoue@heart.med.kyushu-u.ac.jp
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Tanoue
authors.forename: Taketoshi
authors.initials: T
authors.lastname: Maeda
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Oda
authors.forename: Hironori
authors.initials: H
authors.lastname: Baba
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Oishi
authors.forename: Shigehiko
authors.initials: S
authors.lastname: Tokunaga
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Nakashima
authors.forename: Ryuji
authors.initials: R
authors.lastname: Tominaga
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001794:Blood Pressure; D004548:Elasticity; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D020127:Recovery of Function; D012189:Retrospective Studies; D013318:Stroke Volume; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D016277:Ventricular Function, Left; D017725:Ventricular Pressure