title: [NT-proBNP in practice: from chemistry to medicine].
abstract: Since the introduction of routine assay for natriuretic peptides, there are a growing number of clinical applications for those new tests. Numerous studies have defined analytical characteristics and clinical interest of NT-proBNP assay. Originally limited to acute heart failure diagnosis in the emergency room, NT-proBNP assay has now a wide number of applications. This literature review presents the "state of art" of this marker, detailing NT-proBNP physiological recent knowledge and its recognized or investigated clinical applications.
authors.affiliation: Cardiologie, Centre Hospitalier René-Dubos, Pontoise, France.
authors.forename: P
authors.initials: P
authors.lastname: Jourdain
authors.forename: G
authors.initials: G
authors.lastname: Lefèvre
authors.forename: C
authors.initials: C
authors.lastname: Oddoze
authors.forename: V
authors.initials: V
authors.lastname: Sapin
authors.forename: F
authors.initials: F
authors.lastname: Dievart
authors.forename: G
authors.initials: G
authors.lastname: Jondeau
authors.forename: C
authors.initials: C
authors.lastname: Meune
authors.forename: M
authors.initials: M
authors.lastname: Galinier
mesh_terms: D015415:Biomarkers / Q000097:blood; D006331:Heart Diseases / Q000097:blood / Q000175:diagnosis; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood* / Q000502:physiology; D010446:Peptide Fragments / Q000097:blood* / Q000502:physiology
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain