Chromosome segregation: Ndc80 can carry the load.
Dynamic attachments between kinetochores and spindle microtubules are required for chromosome bi-orientation in mitosis. A new study provides biophysical insight into how the Ndc80 complex may contribute to the formation of these attachments.
Joglekar
Ajit P
AP
Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA.
DeLuca
Jennifer G
JG
D020090:Chromosome Segregation; D018386:Kinetochores / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*; D008941:Spindle Apparatus / Q000378:metabolism
C112472:NDC80 protein, S cerevisiae; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins