Regulation of floral patterning by flowering time genes.
Floral patterning in Arabidopsis requires activation of floral homeotic genes by the floral meristem identity gene, LEAFY (LFY). Here we show that precise activation of expression of class B and C homeotic genes in floral meristems is regulated by three flowering time genes, SHORT VEGETATIVE PHASE (SVP), SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1), and AGAMOUS-LIKE 24 (AGL24), through direct control of a LFY coregulator, SEPALLATA3 (SEP3). Orchestrated repression of SEP3 by SVP, AGL24, and SOC1 is mediated by recruiting two interacting chromatin regulators, TERMINAL FLOWER 2/LIKE HETEROCHROMATIN PROTEIN 1 and SAP18, a member of SIN3 histone deacetylase complex. Our finding of coordinated regulation of SEP3 by flowering time genes reveals a hitherto unknown genetic pathway that prevents premature differentiation of floral meristems and determines the appropriate timing of floral organ patterning.
Liu
Chang
C
Department of Biological Sciences and Temasek Life Sciences Laboratory, National University of Singapore, Singapore.
Xi
Wanyan
W
Shen
Lisha
L
Tan
Caiping
C
Yu
Hao
H
D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D035264:Flowers / Q000235:genetics / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D006655:Histone Deacetylases / Q000378:metabolism; D018398:Homeodomain Proteins / Q000378:metabolism; D026161:MADS Domain Proteins / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism
D029681:Arabidopsis Proteins; D002868:Chromosomal Proteins, Non-Histone; D006655:Histone Deacetylases; D018398:Homeodomain Proteins; D026161:MADS Domain Proteins; D014157:Transcription Factors; C419046:AGL20 protein, Arabidopsis; C478065:AGL24 protein, Arabidopsis; C074747:LFY protein, Arabidopsis; C541032:SAP18 protein, Arabidopsis; C121158:SEP3 protein, Arabidopsis; C407549:SVP protein, Arabidopsis; C477788:At5g17690 protein, Arabidopsis