The experience of a sore mouth and associated symptoms in patients with cancer receiving outpatient chemotherapy.
This study aimed to describe sore mouth (SM) severity and distress, associated symptoms, and consequences in cancer chemotherapy outpatients. Secondary analysis was used in this study. A total of 223 patients in 4 treatment centers participated in the study. Data from an intervention study using a computer-based telephone communication system to assess patients' daily symptom experience were analyzed to obtain highest, average, and lowest ratings of severity and distress for SM, fatigue, trouble sleeping, feeling down/blue, and feeling anxious. Consequence data included oral intake, time spent lying down, ability to work, and daily activity. Approximately 51% reported SM, with a mean highest, average, and lowest severity score of 3.1 in cycle 2 and 3.09 in cycle 3. Sore mouth severity was correlated with severity of fatigue, feeling down/blue, feeling anxious, and trouble sleeping. Sore mouth distress was correlated with the same symptoms. Sore mouth severity was correlated with the number of 8-oz glasses of liquid consumed, effect on daily activity, time spent lying down, but not with ability to work. Half of patients experienced SM, which was associated with several other symptoms and led to specific consequences. Understanding the complex symptom experience of patients with SM, including consequences, will assist nurses in developing more comprehensive clinical assessments and interventions. In addition, the association of multiple symptoms with SM will provide a foundation for further research investigation in oral mucositis.
Brown
Carlton G
CG
School of Nursing, University of Delaware, McDowell Hall Rm 361, Newark, DE 19716, USA. carl@carltonbrown.org
McGuire
Deborah B
DB
Peterson
Douglas E
DE
Beck
Susan L
SL
Dudley
William N
WN
Mooney
Kathleen H
KH
D000203:Activities of Daily Living / Q000523:psychology; D000223:Adaptation, Psychological; D000970:Antineoplastic Agents / Q000009:adverse effects; D001294:Attitude to Health; D017281:Cost of Illness; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000451:nursing; D015404:Nursing Methodology Research; D009859:Oncology Nursing; D010045:Outpatients / Q000523:psychology*; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control / Q000523:psychology; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013280:Stomatitis / Q000139:chemically induced / Q000453:epidemiology / Q000523:psychology*; D013315:Stress, Psychological / Q000139:chemically induced / Q000517:prevention & control / Q000523:psychology; D014481:United States
D000970:Antineoplastic Agents