Estimation of stimulus attenuation in cochlear implants.
Neural excitation profile widths at the neural level, for monopolar stimulation with Nucleus straight and contour arrays respectively, were simulated using a combined volume-conduction-neural model. The electrically evoked compound action potential profile widths at the electrode array level were calculated with a simple approximation method employing stimulus attenuation inside the cochlear duct, and the results compared to profile width data from literature. The objective of the article is to develop a simple method to estimate stimulus attenuation values by calculating the values that best fit the modelled excitation profile widths to the measured evoked compound action potential profile widths. Results indicate that the modelled excitation profile widths decrease with increasing stimulus attenuation. However, fitting of modelled excitation profile widths to measured evoked compound action potential profile widths show that different stimulus attenuation values are needed for different stimulation levels. It is suggested that the proposed simple model can provide an estimate of stimulus attenuation by calculating the value of the parameter that produces the best fit to experimental data in specific human subjects.
Smit
Jacoba E
JE
Department of Electrical, Electronic and Computer Engineering, University of Pretoria, Lynnwood Road, Pretoria 0002, South Africa.
Hanekom
Tania
T
Hanekom
Johan J
JJ
D000161:Acoustic Stimulation / Q000295:instrumentation / Q000379:methods*; D000200:Action Potentials / Q000502:physiology*; D000465:Algorithms; D016477:Artifacts; D001299:Audiometry / Q000295:instrumentation / Q000379:methods; D003051:Cochlea / Q000033:anatomy & histology / Q000502:physiology*; D003054:Cochlear Implants; D003056:Cochlear Nerve / Q000502:physiology; D003198:Computer Simulation; D004567:Electrodes, Implanted; D004594:Electrophysiology / Q000295:instrumentation / Q000379:methods; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006198:Hair Cells, Auditory / Q000502:physiology; D006309:Hearing / Q000502:physiology*; D006319:Hearing Loss, Sensorineural / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D009431:Neural Conduction / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted