Aspects of antioxidant foods and supplements in health and disease.
Free radicals generated as byproducts of normal metabolism can damage biologically relevant molecules. When their generation is increased, damage can also be increased, resulting in the development of many pathological conditions. Antioxidant defenses protect the body from the detrimental effects of free radicals. Dietary fruits and vegetables provide a reasonable amount of compounds that act as physiological antioxidants. Although existing knowledge does not allow a final and conclusive assessment of the relevance of antioxidants for health, it does provide the basis for its rational consideration. This paper addresses the specific aspects of antioxidant supplementation in health and disease.
Herrera
Emilio
E
Department of Biochemistry and Molecular Biology, Universidad San Pablo - CEU, Madrid, Spain. eherrera@ceu.es
Jiménez
Rafael
R
Aruoma
Okezie I
OI
Hercberg
Serge
S
Sánchez-García
Isidro
I
Fraga
César
C
D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000975:Antioxidants / Q000008:administration & dosage* / Q000494:pharmacology; D002908:Chronic Disease / Q000517:prevention & control*; D019587:Dietary Supplements; D019317:Evidence-Based Medicine; D015444:Exercise / Q000502:physiology; D005504:Food Analysis; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*; D009753:Nutritive Value; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D017382:Reactive Oxygen Species / Q000009:adverse effects / Q000378:metabolism
D000975:Antioxidants; D017382:Reactive Oxygen Species