[Study on water processing conditions of Realgar].
OBJECTIVE
To optimize the water processing (shui-fei) condition of Realgar.


METHODS
The processing conditions were optimized by L9 (3)4 orthogonal design with three factors as water dose, process times and dryness temperature. The content of dissolved arsenic As(III) in Realgar was tested by High Performance Liquid Chromatography-hydride generation on-line coupled with atomic fluorescence spectrometry (HPLC-HG-AFS).


RESULTS
The optimized conditions were 15 times quantity of water, 8 times for processing and dryness temperature of 40 degrees C.


CONCLUSIONS
The method is accurate and effective,which can be used to evaluate the quality of processed products of Realgar.
Jiang
Hong
H
School of Public Health, China Medical University, Shenyang 110001, China. jianghong@mail.cmu.edu.cn
Ding
Jing-hua
JH
Zhang
Ying-hua
YH
Shi
Song-tian
ST
Gao
Shuang
S
Gong
Hui-zhi
HZ
Sun
Gui-fan
GF
D000704:Analysis of Variance; D001152:Arsenicals / Q000737:chemistry* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D011786:Quality Control; D015203:Reproducibility of Results; D013440:Sulfides / Q000737:chemistry* / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D014867:Water
D001152:Arsenicals; D013440:Sulfides; D014867:Water; C058317:arsenic disulfide