title: [Create mathematical model and analysis of correlation between traditional Chinese medicinal characteristics and neurobehavioral effects].
abstract: In the guidance of system theory, using Multidisciplinary technology to study on the combination of Chinese traditional and western medicine, helps to promote fingding the common points between the Chinese traditional and western medicine. In this article, it intends to create mathematical model and analysis of correlation between Chinese medicinal characteristics and neurobehavioral effects based on literature informatics. The numbers of the Chinese medicines with neurobehavioral effects were worked out within the frame work of 'The China Pharmacopeia' of 2005 edition, from the literature publicized since 1980. The correlation and mathematical model were figured outbetween Chinese medicinal characteristics including traditional functional classification, different tastes as well as channel tropism and immunoregulatory activity based on the statistical software SPSS. The results showed that the neurobehavioral effects was related to the qi-invigorating drugs, yang-invigorating herbs, blood-invigorating herbs, resuscitative drugs and kidney meridian herbs, tastes mild of Chinese medicines (P<0.05). It also accords with the theory of 'Kidney produce marrow' of TCM, The coincidencewas 82.8% between mathematical computing and original classification. There are correlations between Chinese medicinal characteristics and neurobehavioral effects. The mathematical model based on these results can be used for studing of neurobehavioral effects and clinical treatment.
authors.affiliation: Gansu College of Chinese Traditional Medicine, Lanzhou 730000, China. liuyongqi73@163.com
authors.forename: Yongqi
authors.initials: Y
authors.lastname: Liu
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.forename: Ping
authors.initials: P
authors.lastname: Fan
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Wu
mesh_terms: D002681:China; D019411:Clinical Laboratory Techniques; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods / Q000639:trends; D008962:Models, Theoretical; D009422:Nervous System Diseases; D013223:Statistics as Topic
chemical_list: D004365:Drugs, Chinese Herbal