title: The Society of Thoracic Surgeons practice guideline series: guidelines for the management of Barrett's esophagus with high-grade dysplasia.
abstract: The management of Barrett's esophagus with high-grade dysplasia is controversial. The standard of care has traditionally been esophagectomy. However, a number of treatment options aimed at esophageal preservation are increasingly being utilized by many centers. These esophageal-sparing approaches include endoscopic surveillance, mucosal ablation, and endoscopic mucosal resection. In this guideline we review the best evidence supporting these commonly used strategies for high-grade dysplasia to better define management and guide future investigation.
authors.affiliation: Boston University School of Medicine and Department of Cardiothoracic Surgery, Boston Medical Center, Boston, Massachussetts 02118, USA. hiran.fernando@bmc.org
authors.forename: Hiran C
authors.initials: HC
authors.lastname: Fernando
authors.forename: Sudish C
authors.initials: SC
authors.lastname: Murthy
authors.forename: Wayne
authors.initials: W
authors.lastname: Hofstetter
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Shrager
authors.forename: Charles
authors.initials: C
authors.lastname: Bridges
authors.forename: John D
authors.initials: JD
authors.lastname: Mitchell
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Landreneau
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Clough
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Watson
mesh_terms: D001471:Barrett Esophagus / Q000473:pathology / Q000628:therapy*; D001706:Biopsy; D017115:Catheter Ablation; D016629:Esophagectomy; D004945:Esophagoscopy; D006801:Humans; D018579:Patient Selection; D010778:Photochemotherapy; D011159:Population Surveillance