title: [Complete primary distal renal tubular acidosis in children: 11 cases].
abstract: OBJECTIVE
  Analyze the clinical and evolutive particularities of complete primary distal renal tubular acidosis in children,
  
  
  METHODS
  We studied retrospectively 11 cases enrolled in the pediatrics department of Sousse during 10 years period (1993-2002).
  
  
  RESULTS
  It is about 9 boys and 2 girls (sex-ratio = 45) aged 3 month to 5 years (mean age: 18 months). Diagnosis was suspected on clinical and biological data of presumption and confirmed by acidification test. Radiological investigation objectified a nephrocalcinosis in eight patients and urinary lithiasis in two other cases. Auditive exploration showed sensorineural deafness in three patients. The illness appears sporadic in two cases and autosomal recessive in nine other cases. After alkali treatment (sodium bicarbonate), evolution was globally favorable.
authors.affiliation: Service de pédiatrie, CHU Sahloul Sousse.
authors.forename: Jalel
authors.initials: J
authors.lastname: Chemli
authors.forename: Najet
authors.initials: N
authors.lastname: Missaoui
authors.forename: Habib
authors.initials: H
authors.lastname: Selmi
authors.forename: Habib
authors.initials: H
authors.lastname: Miled
authors.forename: Mohamed
authors.initials: M
authors.lastname: Doggi
authors.forename: Ahmed Sahloul
authors.initials: AS
authors.lastname: Essoussi
authors.forename: Abdelaziz
authors.initials: A
authors.lastname: Harbi
mesh_terms: D000141:Acidosis, Renal Tubular / Q000175:diagnosis* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D017693:Sodium Bicarbonate / Q000627:therapeutic use
chemical_list: D017693:Sodium Bicarbonate