title: Application of intraoperative round window electrocochleography for screening the patients with auditory neuropathy.
abstract: BACKGROUND
  Most patients with auditory neuropathy (AN) could receive good even the best effects after cochlear implantation. How to diagnose AN objectively and accurately is very important. In this study, we screened the patients with AN according to the presence or absence of compound action potential (CAP) of intraoperative round window electrocochleography (RW ECochG).
  
  
  METHODS
  Intraoperative RW ECochG was performed on 32 patients with profound sensorineural deafness, who had normal cochlea during cochlear implantation surgery under general anesthesia in the standard operating room. The cochlear microphonic (CM) and CAP of RW ECochG was observed and recorded.
  
  
  RESULTS
  The presence of CM but the absence of CAP of RW ECochG occurred in 12 among the 32 patients. They were suspected to suffer from AN. The rest patients who had CM and CAP of RW ECochG were thought not to suffer from AN.
  
  
  CONCLUSIONS
  Application of intraoperative RW ECochG during the cochlear implantation surgery may objectively and accurately screen the patients with AN, and can give a meaningful clue for implanted device working.
authors.affiliation: Department of Otolaryngology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China.
authors.forename: Lin-e
authors.initials: LE
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Dao-xing
authors.initials: DX
authors.lastname: Zhang
authors.forename: Ke-li
authors.initials: KL
authors.lastname: Cao
mesh_terms: D000293:Adolescent; D000328:Adult; D001300:Audiometry, Evoked Response / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003056:Cochlear Nerve / Q000473:pathology*; D004594:Electrophysiology / Q000379:methods; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012405:Round Window, Ear; D000160:Vestibulocochlear Nerve Diseases / Q000175:diagnosis*; D055815:Young Adult