title: Werner's syndrome: a quite rare disease for differential diagnosis of scleroderma.
abstract: Werner's syndrome (WS) is an autosomal recessive disorder characterized by premature aging. The main features of the disease are scleroderma-like skin appearance, premature atherosclerosis, short stature, diabetes mellitus, early osteoporosis and early aging. Herein, we describe a patient with WS, who has scleroderma-like skin changes and discuss the literature about WS as a disease in the differential diagnosis of systemic sclerosis.
authors.affiliation: Internal Medicine, Rheumatology Department, Izzet Baysal Medical Faculty, Abant Izzet Baysal University, Gölköy, Bolu, Turkey. cemalbes@hotmail.com
authors.forename: Cemal
authors.initials: C
authors.lastname: Bes
authors.forename: Seref
authors.initials: S
authors.lastname: Vardi
authors.forename: Melih
authors.initials: M
authors.lastname: Güven
authors.forename: Mehmet
authors.initials: M
authors.lastname: Soy
mesh_terms: D000328:Adult; D019588:Aging, Premature / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000209:etiology; D016491:Peripheral Vascular Diseases / Q000209:etiology; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000209:etiology; D014898:Werner Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology