title: Feto-maternal risks associated with pregnancy achieved through oocyte donation in a woman with Turner syndrome.
abstract: We report a case of a 40-year-old primipara Caucasian woman with Turner syndrome (TS) and Hashimoto thyroiditis who had underwent a successful IVF-ET cycle with oocyte donation and single embryo transfer. All pregnancies in women with TS are considered as high risk, with cardiovascular complications being the most dangerous. Our case represents a typical case of fetal growth restriction with gradual slowing down of fetal growth after 28 weeks. At 37 + 3 gestational weeks, a healthy male newborn weighing 2240 g, with artery pH of 7.32 was delivered by cesarean section. The neonate was small for gestational age. Women with TS who become pregnant need close surveillance from a multidisciplinary team of cardiologists, obstetricians and endocrinologists. The primary goal is to prevent maternal complications and to improve perinatal outcome. In doing so, a thorough evaluation of fetal growth and uteroplacental and fetal circulation should by no means be omitted, after 26-28 weeks of gestation. The examinations should be at monthly or even shorter intervals to find early signs of growth restriction and act accordingly.
authors.affiliation: Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Patras Medical School, University Hospital, Rion, 26500 Patras, Greece.
authors.forename: Neoklis A
authors.initials: NA
authors.lastname: Georgopoulos
authors.forename: George
authors.initials: G
authors.lastname: Adonakis
authors.forename: Vasilios
authors.initials: V
authors.lastname: Papadopoulos
authors.forename: George A
authors.initials: GA
authors.lastname: Vagenakis
authors.forename: Athanasios
authors.initials: A
authors.lastname: Tsoukas
authors.forename: George
authors.initials: G
authors.lastname: Decavalas
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation; D050031:Hashimoto Disease; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018587:Oocyte Donation; D011247:Pregnancy; D012307:Risk Factors; D014424:Turner Syndrome