title: Secondary Strongyloides stercoralis prophylaxis in patients with human T-cell lymphotropic virus type 1 infection: report of two cases.
abstract: Secondary ivermectin prophylaxis for strongyloidiasis in two patients with human T-cell lymphotropic virus type 1 (HTLV-1)-associated malignancies and fully treated complicated strongyloidiasis is described. Treatment was well tolerated and neither patient developed further manifestations of hyperinfection. As treatment failure for complicated strongyloidiasis has been documented in severely immunosuppressed patients, secondary prophylaxis may be indicated.
authors.affiliation: Postgraduate Training Program, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada.
authors.forename: Laurenna
authors.initials: L
authors.lastname: Peters
authors.forename: Anne E
authors.initials: AE
authors.lastname: McCarthy
authors.forename: Carolyn
authors.initials: C
authors.lastname: Faught
mesh_terms: D000328:Adult; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D018890:Chemoprevention; D017809:Fatal Outcome; D005260:Female; D015490:HTLV-I Infections / Q000150:complications*; D015368:Human T-lymphotropic virus 1 / Q000302:isolation & purification; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use*; D015458:Leukemia, T-Cell / Q000150:complications; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D017171:Strongyloides stercoralis / Q000187:drug effects* / Q000302:isolation & purification; D013322:Strongyloidiasis / Q000150:complications* / Q000469:parasitology / Q000517:prevention & control
chemical_list: D000969:Antinematodal Agents; D007559:Ivermectin