title: The bipolar spectrum: a critical perspective.
abstract: Recent suggestions to extend the boundaries of bipolar disorder to a broader spectrum lead to a concept of bipolarity different from that of classical psychiatry. It has been proposed that many patients with unipolar depression are actually bipolar and that many cases of substance abuse, personality disorders, and childhood behavioral disorders lie within the spectrum. However, since this expanded notion of bipolarity has been defined entirely on the basis of phenomenology, any expansion needs to meet broader criteria for validity. Bipolar spectrum disorders have a different phenomenology, family history, and course than classical bipolar disorders and do not respond in the same way to drugs. Until further research clarifies the boundaries of bipolarity, we should be conservative about extending its scope.
authors.affiliation: Department of Psychiatry, McGill University, Institute of Community and Family Psychiatry and Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Canada. joel.paris@mcgill.ca
authors.forename: Joel
authors.initials: J
authors.lastname: Paris
mesh_terms: D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D008960:Models, Psychological; D019964:Mood Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology; D015203:Reproducibility of Results