title: Association between patient age at the time of surgical treatment for endometriosis and aryl hydrocarbon receptor repressor polymorphism.
abstract: A cross-sectional comparative study among women who underwent surgical treatment for endometriosis revealed that frequency of the Ala/Ala genotype at aryl hydrocarbon receptor repressor (AHRR) Pro185Ala polymorphism was three times higher (27.6% vs. 9.9%) in the younger group (<or=30 years) than in the older group (>30 years). AHHR genotyping may help to identify a subpopulation of women who are susceptible to the earlier onset of endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Hironori
authors.initials: H
authors.lastname: Asada
authors.affiliation: Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Yagihashi
authors.affiliation: Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Furuya
authors.affiliation: Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan. Electronic address: kkosaki@sc.itc.keio.ac.jp.
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kosaki
authors.affiliation: Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Takahashi
authors.affiliation: Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Yoshimura
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D051792:Basic Helix-Loop-Helix Proteins; D004715:Endometriosis / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics* / Q000601:surgery; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D012097:Repressor Proteins / Q000235:genetics*; D014591:Uterine Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics* / Q000601:surgery; D055815:Young Adult
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D012097:Repressor Proteins; C492162:AHRR protein, human