title: NIR fluorescent ytterbium compound for in vivo fluorescence molecular imaging.
abstract: We have developed a new NIR fluorescent probe based on an ytterbium(III) (E)-1-(pyridin-2-yl-diazenyl)naphthalen-2-ol (PAN) complex. This probe emits near-infrared luminescence derived from the Yb ion through excitation of the PAN moiety with visible light (lambda(ex)= 530 nm, lambda(em)= 975 nm). The results support the possible utility of the probe for in vivo fluorescence molecular imaging.
authors.affiliation: Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Aita
authors.forename: Takashi
authors.initials: T
authors.lastname: Temma
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kuge
authors.forename: Koh-ichi
authors.initials: K
authors.lastname: Seki
authors.forename: Hideo
authors.initials: H
authors.lastname: Saji
mesh_terms: D005453:Fluorescence; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011789:Quantum Theory; D019265:Spectroscopy, Near-Infrared; D015018:Ytterbium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D015018:Ytterbium