Prostate cancer: to screen or not to screen?
Unfortunately, interim analyses of the long-awaited ERSPC and PLCO trial data have generated conflicting conclusions. Here, two European authors speculate as to the reasons underlying this contradiction, while highlighting clinically relevant points that are supported by both studies. Particular attention is paid to the potential consequences of overdiagnosis and overtreatment.
Studer
Urs E
UE
Collette
Laurence
L
D055088:Early Detection of Cancer; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000592:standards