title: Electronic interfacing with living cells.
abstract: The direct interfacing of living cells with inorganic electronic materials, components or systems has led to the development of two broad categories of devices that can (1) transduce biochemical signals generated by biological components into electrical signals and (2) transduce electronically generated signals into biochemical signals. The first category of devices permits the monitoring of living cells, the second, enables control of cellular processes. This review will survey this exciting area with emphasis on the fundamental issues and obstacles faced by researchers. Devices and applications that use both prokaryotic (microbial) and eukaryotic (mammalian) cells will be covered. Individual devices described include microbial biofuel cells that produce electricity, bioelectrical reactors that enable electronic control of cellular metabolism, living cell biosensors for the detection of chemicals and devices that permit monitoring and control of mammalian physiology.
authors.affiliation: University of Tennessee, Center for Environmental Biotechnology, 676 Dabney Hall, Knoxville, 37996, TN, USA, jtf@utk.edu.
authors.forename: James T
authors.initials: JT
authors.lastname: Fleming
mesh_terms: D002470:Cell Survival; D002477:Cells / Q000166:cytology*; D055615:Electrical Equipment and Supplies