title: New benzophenone O-glucoside from Hypericum ellipticum.
abstract: Examination of the acetone extract of the aerial parts of Hypericum ellipticum afforded a new acetylated benzophenone glucoside (3'-O-beta-D-3",4",6"-triacetylglucopyranosyl-2,4,5',6-tetrahydroxybenzophenone) together with catechin and epicatechin. The structure of the benzophenone glucoside was determined by 2D NMR spectroscopic data. The compound inhibited the proliferation of CNS tumor cell line (SF-268) and lipid peroxidation in in vitro assays.
authors.affiliation: Department of Chemistry, Susquehanna University, 514 University Avenue, Selinsgrove, PA 17870, USA.
authors.forename: Elyse
authors.initials: E
authors.lastname: Petrunak
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Kester
authors.forename: Yunbao
authors.initials: Y
authors.lastname: Liu
authors.forename: Camile S
authors.initials: CS
authors.lastname: Bowen-Forbes
authors.forename: Muraleedharan G
authors.initials: MG
authors.lastname: Nair
authors.forename: Geneive E
authors.initials: GE
authors.lastname: Henry
mesh_terms: D001577:Benzophenones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D054697:Cytostatic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D020902:Hypericum / Q000737:chemistry*; D015227:Lipid Peroxidation / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: C542120:3'-O-3'',4'',6''-triacetylglucopyranosyl-2,4,5',6-tetrahydroxybenzophenone; D001577:Benzophenones; D054697:Cytostatic Agents; D005960:Glucosides; D002392:Catechin