[Comparing the dissolution of Rb1 from the micropowder and common powder of Radix Panacis Quinquefolii].
OBJECTIVE
To compare the dissolution of Rb1 from the micropowder and common powder of Radix Panacis Quinquefolii in vitro.


METHODS
The contents of Ginsenoside Rb1 in micropowder (99% over 0-30 microm) and common powder (180 microm) with and without the barrier of dialytic membrane were determined at different time by HPLC.


RESULTS
The speed and degree of dissolution of Ginsenoside Rb1 in micropowder were better than those in common powder (15-45 min, P < 0.05; 45-60 min, P < 0.01).


CONCLUSIONS
The dissolution of effective components in Radix Panacis Quinquefolii can be improved by SFCT.
Zhai
Xu-feng
XF
Nanfang Lee Kum Kee Co., Ltd, Guangzhou 510665, China. xf_zhai@nflkk.com
Zhang
Chen
C
Guo
Xiao-lei
XL
D002851:Chromatography, High Pressure Liquid; D036145:Ginsenosides / Q000737:chemistry / Q000302:isolation & purification*; D005894:Panax / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011208:Powders; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
D036145:Ginsenosides; D011208:Powders; C442759:ginsenoside Rb1