title: Combined cementoplasty and radiofrequency ablation in the treatment of painful neoplastic lesions of bone.
abstract: OBJECTIVE
  To assess the safety and effectiveness of combined radiofrequency (RF) ablation and cementoplasty in the treatment of painful neoplastic lesions of bone.
  
  
  METHODS
  The authors performed a retrospective analysis of 25 combined treatments comprising RF ablation followed by injection of polymethylmethacrylate cement performed in 19 patients during a 22-month period. Patients ranged in age from 42 to 82 years (mean, 58.9 years) and included five women and 14 men. Eleven vertebrae (eight lumbar and three thoracic), nine acetabulae, three sacra, one pubis, and one humerus were treated with a total of 36 RF ablations (in several instances, overlapping ablations were used). The location of the primary neoplasm, lesion size, pain before and after the procedure (as determined with a 10-point visual analog scale [VAS]), number of RF treatments, type of device used for cementoplasty, RF time, cement volume, and extravasation were documented.
  
  
  RESULTS
  A total of 25 combined RF ablations and cementoplasties were performed. The technical success rate was 100% (25 of 25 treatments). There were seven minor complications: six limited cement extravasations and a transient thermal nerve injury. The mean RF time was 9.1 minutes (range, 6-12 minutes). The mean cement volume injected was 6.1 mL (range, 0.8-16 mL). The mean preprocedure pain (as measured with a VAS) was 7.9 (range, 7.0-9.0) and the mean posttreatment pain was 4.2 (range, 0-6); the difference was statistically significant (mean score, 4.08; 95% confidence interval: 3.92, 4.87; P < .0001) using a paired t test.
  
  
  CONCLUSIONS
  Combined RF ablation and cementoplasty appears to be safe and effective in the treatment of painful neoplastic lesions of bone.
authors.affiliation: Department of Radiology, Vancouver General Hospital, University of British Columbia, 899 W 12th Ave, Vancouver, BCV52 1M9 Canada. peter.munk@vch.ca
authors.forename: Peter L
authors.initials: PL
authors.lastname: Munk
authors.forename: Faisal
authors.initials: F
authors.lastname: Rashid
authors.forename: Manraj K
authors.initials: MK
authors.lastname: Heran
authors.forename: Michael
authors.initials: M
authors.lastname: Papirny
authors.forename: David M
authors.initials: DM
authors.lastname: Liu
authors.forename: David
authors.initials: D
authors.lastname: Malfair
authors.forename: Maziar
authors.initials: M
authors.lastname: Badii
authors.forename: Paul W
authors.initials: PW
authors.lastname: Clarkson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements / Q000627:therapeutic use*; D017115:Catheter Ablation / Q000379:methods*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D013125:Spinal Neoplasms / Q000150:complications / Q000628:therapy*; D013904:Thoracic Vertebrae / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods*
chemical_list: D001843:Bone Cements