Silica-bound benzoyl chloride mediated the solid-phase synthesis of 4H-3,1-benzoxazin-4-ones.
The solid-phase synthesis of 4H-3,1-benzoxazin-4-ones was achieved using silica-bound benzoyl chloride (SBBC) as dehydrating agent in reaction with 2-acylaminobenzoic acids. The silica-grafted reagent (SBBC) was simply recovered after reaction and reused several times.
Rad-Moghadam
Kurosh
K
Chemistry Department, University of Guilan, P.O. Box 41335-19141, Rasht, Iran. radmm@guilan.ac.ir
Rouhi
Somayeh
S