title: The duration of inpatient admission predicts cognitive functioning at discharge in patients with bipolar disorder.
abstract: Previous studies of cognitive functioning in bipolar disorder generally indicate that a more severe course of illness is associated with greater cognitive impairment. In particular, a history of greater number and longer duration of mood episodes predicts enduring cognitive deficits in euthymic patients. Shifting the focus of this investigation to the cognitive effects of a discrete mood episode, the current study aimed to explore whether patients who require a longer hospitalization to stabilize from an acute episode of mood disturbance present with more compromised cognitive functioning during the phase of early recovery. For this purpose, the study examined the link between the duration of inpatient admission and neuropsychological test scores at the time of discharge in 41 patients with bipolar disorder. Participants were assigned to long (n = 20) and short (n = 21) stay groups using a median split (M = 12). Results indicated that longer admissions were associated with more severe deficits in executive functioning at discharge after controlling for residual mood symptoms and previous number of psychiatric admissions. Findings from the current study may inform discharge planning for patients with bipolar disorder after an extended hospital stay.
authors.affiliation: Department of Psychiatry, Harvard Medical School/McLean Hospital, MA, USA. boaz_levy@hms.harvard.edu
authors.forename: Boaz
authors.initials: B
authors.lastname: Levy
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Stephansky
authors.forename: Kris C
authors.initials: KC
authors.lastname: Dobie
authors.forename: Benedetta A
authors.initials: BA
authors.lastname: Monzani
authors.forename: Anna Marie
authors.initials: AM
authors.lastname: Medina
authors.forename: Roger D
authors.initials: RD
authors.lastname: Weiss
mesh_terms: D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care / Q000592:standards; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D010343:Patient Admission / Q000706:statistics & numerical data; D010347:Patient Care Planning / Q000592:standards; D010351:Patient Discharge / Q000706:statistics & numerical data; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011594:Psychometrics; D012720:Severity of Illness Index; D013997:Time Factors