title: Genotoxic effects of nonylphenol and bisphenol A exposure in aquatic biomonitoring species: freshwater crustacean, Daphnia magna, and aquatic midge, Chironomus riparius.
abstract: The geno-, and eco-toxicity of nonlyphenol (NP) and bisphenol A (BPA) were investigated in Daphnia magna, and Chironomus riparius. BPA may exert a genotoxicity on both species, whereas NP-induced DNA damage occurred only in C. riparius. In NP-exposed D. magna, increased mortality, without effect on DNA integrity was observed, an example of a false-negative result from the biomarkers perspective. False-positive results from the genotoxicity were observed in BPA-exposed D. magna and in NP-exposed C. riparius. Considering the importance of genotoxic biomarkers in ecotoxicity monitoring, DNA damage in these species could provide useful information.
authors.affiliation: Faculty of Environmental Engineering, College of Urban Science, University of Seoul, 90 Jeonnong-dong, Dongdaemun-gu, Seoul 130-743, Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Park
authors.forename: Jinhee
authors.initials: J
authors.lastname: Choi
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds; D002683:Chironomidae; D004249:DNA Damage / Q000187:drug effects; D003621:Daphnia; D004784:Environmental Monitoring / Q000379:methods; D009152:Mutagenicity Tests; D010636:Phenols / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; D014874:Water Pollutants, Chemical; C025256:nonylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds