title: Nonenhancing brain metastases.
abstract: The hallmark radiological finding in metastatic brain disease is multiple enhancing lesions. We report a case of metastatic lung cancer to the brain with a lack of contrast enhancement. We believe that this unusual finding is due to inadvertent "treatment" of the metastases with the antiangiogenic agent bevacizumab (Avastin).
authors.affiliation: Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. karimis@mskcc.org
authors.forename: Sasan
authors.initials: S
authors.lastname: Karimi
authors.forename: Eric
authors.initials: E
authors.lastname: Lis
authors.forename: Saba
authors.initials: S
authors.lastname: Gilani
authors.forename: Nicholas
authors.initials: N
authors.lastname: D'Ambrosio
authors.forename: Andrei
authors.initials: A
authors.lastname: Holodny
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000556:secondary; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary; D001932:Brain Neoplasms / Q000188:drug therapy / Q000556:secondary*; D003287:Contrast Media; D018450:Disease Progression; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D003287:Contrast Media