Diesel exhaust, thrombus formation, and Kounis syndrome: a potential association.
Diesel exhaust (DE) is associated with triggering acute myocardial infarction. Furthermore, DE can induce and exacerbate hypersensitivity responses, amplify the production of a variety of chemokines and cytokines, facilitate interactions between inflammatory cells and act as allergen transporter. Therefore Kounis syndrome Type I which includes patients with normal coronary arteries, and Type II variant which applies to individuals with quiescent preexisting atheromatous disease can be the result of these hypersensitivity processes.
Hahalis
George
G
Medical Sciences, Patras Highest Institute of Education and Technology, Patras, Greece.
Kounis
George N
GN
Soufras
George D
GD
Kouni
Sophia A
SA
Kounis
Nicholas G
NG
D054058:Acute Coronary Syndrome / Q000145:classification / Q000175:diagnosis / Q000209:etiology*; D050197:Atherosclerosis / Q000145:classification / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology; D019570:Inhalation Exposure / Q000009:adverse effects*; D052638:Particulate Matter / Q000009:adverse effects; D001335:Vehicle Emissions
D052638:Particulate Matter; D001335:Vehicle Emissions