title: Voyages of discovery.
abstract: The metabolism of calcium and bone is controlled by five principal hormones: parathyroid hormone, 1,25-dihydroxyvitamin D, calcitonin, parathyroid hormone-related peptide and fibroblast growth factor 23, some of which have been known for several decades and some of which have only recently been identified. The stories of discovery of these hormones have constituted a series of complex journeys which have been undertaken over the past century or so and none of which has yet been completed. The complexities of bone and calcium metabolism have been and remain, to many people, somewhat mysterious and a daunting task to understand. This book is designed to try to unravel those mysteries and present them in an interesting and comprehensible manner.
authors.affiliation: Department of Paediatric Endocrinology, Royal London Hospital, Whitechapel, London, UK. jeremy.allgrove@bartsandthelondon.nhs.uk
authors.forename: Jeremy
authors.initials: J
authors.lastname: Allgrove
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D002116:Calcitonin / Q000502:physiology; D002118:Calcium / Q000378:metabolism*; D002648:Child; D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000378:metabolism / Q000502:physiology; D006728:Hormones / Q000502:physiology*; D006801:Humans; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism / Q000502:physiology; D014815:Vitamins / Q000502:physiology*
chemical_list: D006728:Hormones; D044162:Parathyroid Hormone-Related Protein; D014815:Vitamins; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23; D002116:Calcitonin; D002118:Calcium