title: Impact of pressure ulcers on quality of life in older patients: a systematic review.
abstract: OBJECTIVE
  To identify the impact of pressure ulcers (PUs) and PU interventions on health-related quality of life (HRQL).
  
  
  METHODS
  Systematic review and metasynthesis of primary research reporting the impact of PU and PU interventions on HRQL according to direct patient reports. Quality assessment criteria were developed and applied. Data extraction identified findings in the form of direct quotes from patients or questionnaire items and domain results. Combined synthesis of qualitative and quantitative research was performed using content analysis to generate categories and themes from findings. Thirteen electronic databases were searched, and hand searching, cross-referencing, contact with experts, and an online search was undertaken. No language restrictions were applied.
  
  
  METHODS
  Adults with PUs in acute, community, and long-term care settings across Europe, the United States, Asia, and Australia.
  
  
  METHODS
  Thirty-one studies including 2,463 participants with PUs were included in the review. Ages ranged from 17 to 96.
  
  
  RESULTS
  The review included 10 qualitative and 21 quantitative studies; 293 findings, 46 categories, and 11 themes emerged. The 11 HRQL themes were physical impact, social impact, psychological effect, PU symptoms, general health, and other impacts of PUs: healthcare professional-client relationships, need for versus effect of interventions, impact on others, financial impact, perceived etiology, and need for knowledge.
  
  
  CONCLUSIONS
  There is evidence that PUs and PU interventions have a significant impact on HRQL and cause substantial burden to patients.
authors.affiliation: Clinical Trials Research Unit, University of Leeds, Leeds, United Kingdom. c.gorecki@leeds.ac.uk
authors.forename: Claudia
authors.initials: C
authors.lastname: Gorecki
authors.forename: Julia M
authors.initials: JM
authors.lastname: Brown
authors.forename: E Andrea
authors.initials: EA
authors.lastname: Nelson
authors.forename: Michelle
authors.initials: M
authors.lastname: Briggs
authors.forename: Lisette
authors.initials: L
authors.lastname: Schoonhoven
authors.forename: Carol
authors.initials: C
authors.lastname: Dealey
authors.forename: Tom
authors.initials: T
authors.lastname: Defloor
authors.forename: Jane
authors.initials: J
authors.lastname: Nixon
mesh_terms: D000368:Aged; D006801:Humans; D003668:Pressure Ulcer / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control / Q000523:psychology; D011788:Quality of Life; D012307:Risk Factors