3S-fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR.
Variable-temperature inversion transfer NMR is used to determine the kinetic and thermodynamic parameters of cis-trans isomerization of N-Ac-(3R) and (3S)-fluoroproline-OMe.
Thomas
Colin A
CA
Department of Chemistry, Wichita State University, Wichita, KS 67260-0051, USA.
Talaty
Erach R
ER
Bann
James G
JG
D017666:Deuterium Oxide / Q000737:chemistry; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry; D017510:Protein Folding; D013237:Stereoisomerism; D013816:Thermodynamics
D011392:Proline; D017666:Deuterium Oxide