title: Selective detection of antibodies in microstructured polymer optical fibers.
abstract: We demonstrate selective detection of fluorophore labeled antibodies from minute samples probed by a sensor layer of complementary biomolecules immobilized inside the air holes of microstructured Polymer Optical Fiber (mPOF). The fiber core is defined by a ring of 6 air holes and a simple procedure was applied to selectively capture either alpha-streptavidin or alpha-CRP antibodies inside these air holes. A sensitive and easy-to-use fluorescence method was used for the optical detection. Our results show that mPOF based biosensors can provide reliable and selective antibody detection in ultra small sample volumes.
authors.forename: Jesper
authors.initials: J
authors.lastname: Jensen
authors.forename: Poul
authors.initials: P
authors.lastname: Hoiby
authors.forename: Grigoriy
authors.initials: G
authors.lastname: Emiliyanov
authors.forename: Ole
authors.initials: O
authors.lastname: Bang
authors.forename: Lars
authors.initials: L
authors.lastname: Pedersen
authors.forename: Anders
authors.initials: A
authors.lastname: Bjarklev