Cutaneous metastases of malignant melanoma--how difficult can it be?
Malignant melanoma is one of the most aggressive skin neoplasms with histopathological-based therapeutic approach. Unfortunately, in some cases, even the elementary issue of dealing with a primary or metastatic lesion may be sometimes incredible difficult to settle. We studied 11 cases of malignant melanomas that required careful histopathological and immunohistochemical analysis to differentiate between primary and secondary tumor. We evaluated epidermotropism of primary MM including synchronous tumors, local recurrences and metastases.
Zurac
Sabina
S
Department of Pathology, Colentina University Hospital, Romania. sabina_zurac@yahoo.com
Andrei
R
R
Petsakos
G
G
Nichita
Luciana
L
Bastian
Alexandra
A
Micu
Gianina
G
Gramadă
Eliza
E
Popp
Cristiana
C
Stăniceanu
Florica
F
Petrescu
Stefana
S
Negroiu
Gabriela
G
Giurcăneanu
Dorina
D
Chiţu
Virginia
V
D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008545:Melanoma / Q000175:diagnosis / Q000556:secondary*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000556:secondary*