title: Salt taste sensitivity threshold and exercise-induced hypertension.
abstract: Salt taste sensitivity is the capacity to identify the flavour of salt. It is possible that salt taste sensitivity threshold (STST) can influence salt appetite, and sodium ingestion is associated with hypertension. The present study evaluates the relationship between salt taste sensitivity threshold (STST) and blood pressure (BP) response to exercise during a treadmill stress test. Two hundred and three normotensive individuals undergoing evaluation before starting an exercise training program were tested for STST, using concentrated saline solutions from 0.22 to 58.4g/L. Patients were divided into two groups according to the STST: normal (n-STST) and increased (i-STST); and into two groups according to their BP response to exercise: exercise-induced hypertension (EIH) or physiological blood pressure response (n-EIH). EIH was detected in 49 (24.1%) individuals. Initial systolic and diastolic BP and their areas under the curves during the test were higher in the EIH group. Initial systolic and diastolic BP areas under the curves were significantly higher in i-STST than n-STST. There was an association between STST of at least 1.8g/L (increased STST) and EIH (OR=6.71, 95% CI 1.5-29.99) independent of gender, body mass index and age. Occurrence of EIH was associated to i-STST, suggesting that a relationship between high STST and increased BP response to exercise is possible.
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil; Cardiology Department Ergometry Unit, Pontifícia Universidade Católica do Rio Grande do Sul. Porto Alegre, Brazil. Electronic address: mrabin@uol.com.br.
authors.forename: Mendel
authors.initials: M
authors.lastname: Rabin
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil.
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Poli de Figueiredo
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil.
authors.forename: Mario Bernardes
authors.initials: MB
authors.lastname: Wagner
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil.
authors.forename: Ivan Carlos Ferreira
authors.initials: ICF
authors.lastname: Antonello
mesh_terms: D000328:Adult; D019540:Area Under Curve; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003971:Diastole / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology*; D016015:Logistic Models; D008297:Male; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*; D013599:Systole / Q000502:physiology; D013652:Taste Threshold / Q000502:physiology*
chemical_list: D017673:Sodium Chloride, Dietary