[Enterobacter sakazakii in powdered infant food formulas].
Species of the Cronobacter genus ("Enterobacter sakazakii" s. l.) are emergent food-borne pathogens that can cause rare but severe neonatal meningitis, bacteriaemia, and necrotizing enterocolitis. Preterm, low-birth-weight, and immuno-compromised infants exposed to these bacterial species are at particular risk. Over the last 50 years, the literature has reported, mainly in newborn children, more than one hundred cases of infection due to these pathogens. The objective of this review was to synthesize the recent advances in knowledge of species of the Cronobacter genus, in particular with regards to taxonomy, physiology, pathogenicity, clinical cases, the methods for detection, isolation, and characterization, and their presence in powdered formulae for infants and young children, which were identified as the main infection vector. Researchers and international public health authorities have explored the ways contamination occur to better control the risks of pathogen development. Appropriate analysis and control measures were implemented in areas processing powdered formulae for infants and young children, and caregivers and families were informed to undertake good hygienic practices.
Proudy
Isabelle
I
Service de microbiologie, Equipe d'accueil 2128, Centre hospitalier universitaire, Université de Caen Basse-Normandie, avenue Côte de Nacre, Caen CEDEX, France. isabelle.proudy@rennes.inra.fr
D044083:Cronobacter sakazakii / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology*; D005516:Food Microbiology; D006801:Humans; D007223:Infant; D041943:Infant Formula; D007231:Infant, Newborn; D017053:Infection Control / Q000379:methods