title: Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain.
abstract: Diffuse optical correlation methods were adapted for three-dimensional (3D) tomography of cerebral blood flow (CBF) in small animal models. The image reconstruction was optimized using a noise model for diffuse correlation tomography which enabled better data selection and regularization. The tomographic approach was demonstrated with simulated data and during in-vivo cortical spreading depression (CSD) in rat brain. Three-dimensional images of CBF were obtained through intact skull in tissues(~4mm) deep below the cortex.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhou
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Yu
authors.forename: Daisuke
authors.initials: D
authors.lastname: Furuya
authors.forename: Joel
authors.initials: J
authors.lastname: Greenberg
authors.forename: Arjun
authors.initials: A
authors.lastname: Yodh
authors.forename: Turgut
authors.initials: T
authors.lastname: Durduran