title: A novel non-enzymatic ECL sensor for glucose using palladium nanoparticles supported on functional carbon nanotubes.
abstract: A novel non-enzymatic electrochemiluminescence (ECL) sensor based on palladium nanoparticles (PdNPs)-functional carbon nanotubes (FCNTs) was discovered for glucose detection. PdNPs were homogeneously modified on FCNTs using a facile spontaneous redox reaction method. Their morphologies were characterized by transmission electron microscopy (TEM). Based on ECL experimental results, the PdNPs-FCNTs-Nafion film modified electrode displayed high electrocatalytic activity towards the oxidation of glucose. The free radicals generated by the glucose oxidation reacted with the luminol anion (LH(-)), and enhanced the ECL signal. Under the optimized conditions, the linear response of ECL intensity to glucose concentration was valid in the range from 0.5 to 40 micromol L(-1) (r(2)=0.9974) with a detection limit (S/N=3) of 0.09 micromol L(-1). In addition, the modified electrode presented high resistance towards the poisoning of chloride ion, high selectivity and long-term stability. In order to verify the sensor reliability, it was applied to the determination of glucose in glucose injection samples. The results indicated that the proposed approach provided a highly sensitive, more facile method with good reproducibility for glucose determination, promising the development of a non-enzymatic ECL glucose sensor.
authors.affiliation: Department of Chemistry and Key Laboratory of Analytical Sciences of the Ministry of Education, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Xiao-mei
authors.initials: XM
authors.lastname: Chen
authors.forename: Zhi-min
authors.initials: ZM
authors.lastname: Cai
authors.forename: Zhi-jie
authors.initials: ZJ
authors.lastname: Lin
authors.forename: Tian-tian
authors.initials: TT
authors.lastname: Jia
authors.forename: Hai-zhu
authors.initials: HZ
authors.lastname: Liu
authors.forename: Ya-qi
authors.initials: YQ
authors.lastname: Jiang
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004563:Electrochemistry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D008163:Luminescent Measurements / Q000295:instrumentation*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D010165:Palladium / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D010165:Palladium; D005947:Glucose