Sequencing of four new HLA-C alleles, Cw*070403, Cw*0757, Cw*1705, and Cw*0223.
Sequencing-based typing for unrelated hematopoietic stem cell transplantation studies rendered four new HLA-C alleles. HLA-Cw*0757, Cw*070403, and Cw*1705 differ by single point mutations from their most similar alleles, Cw*070105, Cw*070401, and Cw*1701, respectively. In contrast, Cw*0223 discloses five amino acid replacements at the alpha2 domain regarding Cw*020202.
Balas
A
A
Departamento de Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain. abalas.trans@salud.madrid.org
Bustamante
L
L
García-Sánchez
F
F
Vicario
J L
JL
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D015236:HLA-C Antigens