Diverse immune responses to orally administered heat-killed cell preparation of Enterococcus faecalis strain EC-12 in murine immune tissues.
Diverse immune responses to an orally administered heat-killed cell preparation of Enterococcus faecalis strain EC-12 (EC-12) among jejunal-Peyer's patches (PPs), ileal-PPs, mesenteric lymph nodes (MLNs), and spleen were compared by real-time PCR in mice. Intriguingly, distinct responses to EC-12 were observed in the various tissues. This study indicates a site-specific response to orally administered bacteria, particularly in jejunal- and ileal-PPs.
Yoshikawa
Tohru
T
Laboratory of Animal Science, Kyoto Prefectural University, Shimogamo, Kyoto, Japan.
Inoue
Ryo
R
Yoshida
Yoko
Y
Watanabe
Takumi
T
Bukawa
Wakoto
W
Ushida
Kazunari
K
D000284:Administration, Oral; D000818:Animals; D013293:Enterococcus faecalis / Q000276:immunology*; D006358:Hot Temperature; D051379:Mice; D016133:Polymerase Chain Reaction