title: Clear (pale) cell acanthosis as an incidental finding.
abstract: Different patterns of epidermal change, including epidermolytic hyperkeratosis and acantholytic dyskeratosis, may represent the predominant histopathologic finding in several localized and generalized processes. Occasionally, minute foci of these reaction patterns are identified as an incidental finding in a biopsy taken because of the presence of some other lesion. Clear (pale) cell acanthosis may occur as the main histologic alteration in clear (pale) cell acanthoma or incidentally, such as may be seen within a seborrheic keratosis. Two cases of incidental minute foci of clear (pale) cell acanthosis are described and put into the broader context of other epidermal histologic reaction patterns.
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA. christine.ko@yale.edu
authors.forename: Christine J
authors.initials: CJ
authors.lastname: Ko
authors.forename: Antonio
authors.initials: A
authors.lastname: Subtil
mesh_terms: D005260:Female; D006801:Humans; D033162:Incidental Findings; D017492:Keratosis, Seborrheic / Q000150:complications / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000150:complications; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000150:complications; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications