title: Cleft lip and/or palate and breathing during sleep.
abstract: Cleft of the lip and/or palate (CL/P) is a common defect which is associated with changes in facial structures and a smaller upper airway. As a result, infants and children with CL/P have an increased risk of sleep disordered breathing (SDB). This paper will review the anatomical and functional factors which place infants and children with CL/P at increased risk of SDB as well as review the literature which defines the magnitude of this risk. The information available on treatment of SDB in infants and children with CL/P will be presented. Finally, outstanding issues relevant to SDB in children with CL/P are discussed with direction for future research.
authors.affiliation: Discipline of Paediatrics & Child Health, Faculty of Medicine, University of Sydney, NSW, Australia. JoannaM4@med.usyd.edu.au
authors.forename: Joanna E
authors.initials: JE
authors.lastname: MacLean
authors.forename: Peter
authors.initials: P
authors.lastname: Hayward
authors.forename: Dominic A
authors.initials: DA
authors.lastname: Fitzgerald
authors.forename: Karen
authors.initials: K
authors.lastname: Waters
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D002972:Cleft Palate / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D045422:Continuous Positive Airway Pressure; D006801:Humans; D007223:Infant; D012143:Respiratory Physiological Phenomena; D012307:Risk Factors; D012890:Sleep / Q000502:physiology; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000628:therapy