Relationship between the degree of cardiovascular adaptation and Th1/Th2 polarization of immune response.
The main parameters of humoral immunity during medium intensity exercise were studied in oarsmen with high and low cardiovascular adaptation. A relationship between high cardiovascular adaptation to exercise and immune response polarization by the Th2 mechanism was demonstrated. Increased production of IL-10 in response to physical stress plays a key role in this relationship.
Donnikov
A E
AE
DNA-Technology Company, Moscow, Russia. donnikov@dna-technology.ru
Shkurnikov
M U
MU
Akimov
E B
EB
Tonevitsky
A G
AG
D000222:Adaptation, Physiological / Q000502:physiology*; D000293:Adolescent; D000917:Antibody Formation / Q000276:immunology; D002319:Cardiovascular System; D015444:Exercise / Q000502:physiology; D006801:Humans; D016753:Interleukin-10 / Q000378:metabolism; D008954:Models, Biological; D018417:Th1 Cells / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
D016753:Interleukin-10