title: Magnetoencephalography evaluation of febrile seizures in young children.
abstract: The aim of this study is to assess any cerebral dysfunction in young children, who experienced febrile seizures, by means of magnetoencephalography. Our study population included 15 children (9 boys, 6 girls) within the age range of 2 to 7 years. The magnetoencephalography data were recorded with a 122-channel biomagnetometer. Equivalent current dipoles were calculated for epileptic spikes on magnetoencephalography recordings according to the single dipole model. Of 15 children, 8 showed equivalent current dipoles that located at the left-temporal, right-temporal, occipital, and frontal lobe, as active regions responsible for febrile seizures. We assumed that the interictal epileptiform discharges are a consequence of febrile seizures. Of course, further study in a larger number of patients is needed to evaluate the exact role of the equivalent current dipoles, in young children, who experienced febrile seizures.
authors.affiliation: Lab of Medical Physics and Department of Pediatrics, Medical School Democritus University of Thrace, Alex/polis, Greece.
authors.forename: Photios
authors.initials: P
authors.lastname: Anninos
authors.forename: Athanasia
authors.initials: A
authors.lastname: Kotini
authors.forename: Aggelos
authors.initials: A
authors.lastname: Tsalkidis
authors.forename: Vasiliki
authors.initials: V
authors.lastname: Dipla
authors.forename: Athanasios
authors.initials: A
authors.lastname: Chatzimichael
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D001931:Brain Mapping / Q000295:instrumentation / Q000379:methods; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004830:Epilepsy, Tonic-Clonic / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography / Q000295:instrumentation / Q000379:methods*; D008297:Male; D010865:Pilot Projects; D012535:Scalp / Q000503:physiopathology; D003294:Seizures, Febrile / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed