[Laboratory criteria of systemic inflammatory syndrome by surgical abdominal infections].
Results of treatment of 116 patients with acute appendicitis, cholecystitis pancreatitis and other inflammatory diseases of the abdominal cavity, complicated with peritonitis in 53 cases, are analyzed. The concentrations of interleukine-6 (IL-6), tumor necrosis factor small be, Cyrillic (TNF-6) and its soluble receptor in peripheral blood were used as systemic inflammatory response indicators. The increase of IL-6 and soluble TNF-6 receptor concentrations correlated with the augmentation of inflammatory response. The Willebrand factor with plasma activity of 180-200% can be used as an early indicator of inflammatory response in patients with acute abdominal diseases. The higher activity of the Willebrand factor is associated with multiple organ failure syndrome.
Makarov
A I
AI
Vorob'eva
N A
NA
Dobrodeeva
L K
LK
Makarova
V I
VI
D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000097:blood / Q000150:complications*; D012720:Severity of Illness Index; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood* / Q000209:etiology; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*; D014841:von Willebrand Factor / Q000378:metabolism*
D015415:Biomarkers; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D014841:von Willebrand Factor