Collapsing glomerulopathy as a complication of interferon therapy for hepatitis C infection.
We present the case of a patient with chronic hepatitis C and diabetes, who rapidly progressed to end stage renal disease upon initiation of IFNalpha therapy for his HCV infection. A kidney biopsy revealed advanced collapsing glomerulopathy.
Kanungo
Sriraj
S
Division of Nephrology, Department of Internal Medicine, Saint Louis University School of Medicine, 3635 Vista Ave., St Louis, MO 63110, USA.
Tamirisa
Srinath
S
Gopalakrishnan
Rajalakshmi
R
Salinas-Madrigal
Luis
L
Bastani
Bahar
B
D000998:Antiviral Agents / Q000009:adverse effects*; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects*; D007676:Kidney Failure, Chronic / Q000139:chemically induced* / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D008875:Middle Aged
D000998:Antiviral Agents; D016898:Interferon-alpha