[Aprotinin scintigraphy in amyloidosis].
Amyloidosis is a disease characterized by protein deposition (amyloid) in THE extracellular matrix leading to organ dysfunction and death. New treatment modalities have emphasized the need for accurate and early diagnosis. Aprotinin scintigraphy is a radionuclide imaging technique in which the localisation and extent of amyloid deposits are visualized. It is specific and sensitive in detecting cardiac amyloidosis, which is associated with a poor prognosis. In addition, aprotinin scintigraphy appears to be a useful tool for the monitoring of disease progression and treatment efficacy.
Haraldsen
Ate
A
Afdelingen for Klinisk Fysiologi og Nuklearmedicin, Arhus Universitetshospital, Skejby, DK-8200 Arhus N.
Eskild-Jensen
Anni
A
Frøkiaer
Jørgen
J
D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000628:therapy; D007611:Aprotinin; D009202:Cardiomyopathies / Q000000981:diagnostic imaging / Q000628:therapy; D042241:Early Diagnosis; D006801:Humans; D015609:Organotechnetium Compounds; D011379:Prognosis; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity
D015609:Organotechnetium Compounds; C041381:technetium Tc 99m aprotinin; D007611:Aprotinin