title: Concise total synthesis of (+)-aspergillide B.
abstract: An efficient total synthesis of (+)-aspergillide B has been achieved, which features the C-glycosylation reaction for constructing the 2,6-trans-substituted pyran core, a highly effective four-step sequence without purification to produce the key intermediate 13 and an advantegous E-selective Julia-Kocienski olefination on a highly elaborate substrate. The synthesis confirmed the revised structure of aspergillide B by Uenishi.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.forename: Jinmei
authors.initials: J
authors.lastname: He
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.forename: Xinfu
authors.initials: X
authors.lastname: Pan
authors.forename: Xuegong
authors.initials: X
authors.lastname: She
mesh_terms: D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D018942:Macrolides; C526625:aspergillide B