Degree of risk related to procedures performed in conjunction with surgical myocardial revascularization in octogenarians.
OBJECTIVE
We determined the degree of risk produced by the association of other surgical procedures with surgical myocardial revascularization in octogenarian patients and identified the risk factors that best explain hospital mortality.


METHODS
This study was an observational analytical historical cohort study involving octogenarians operated on at our institution between January 1, 2000 and January 1, 2005. We stratified the objective population as follows: Group 1 comprised octogenarians revascularized without associated procedures, and Group 2 comprised octogenarians revascularized with associated procedures. Statistical analyses included the t test for independent samples and multiple logistic regression analysis. Significance was accepted with an alpha error of 5%.


RESULTS
Univariate analyses revealed the following clinical and statistically significant variables: hospital mortality (P=0.002), diabetes mellitus (P=0.017), preoperative endocarditis (P=0.001), cardiogenic shock (P=0.019), use of an intra-aortic balloon pump (P=0.026), preoperative risk score (Parsonnet), P<0.001, procedure associated with revascularization (P<0.001), medium number of affected coronary arteries (P<0.001), use of extracorporeal circulation (P<0.001), time of extracorporeal circulation (P<0.001), number of distal anastomoses (P=0.002), graft type (P<0.001), postoperative breathing support (P<0.001), stroke (P<0.001), infection (P=0.002), creatinine level (P=0.018), and quality of life score (P=0.050).


CONCLUSIONS
In octogenarian patients, the need for a procedure associated with surgical myocardial revascularization produces an absolute increase in hospital mortality risk of 45%. The variables that contributed to hospital mortality were preoperative endocarditis, preoperative cardiogenic shock, the use of extracorporeal circulation, the length of time of extracorporeal circulation, postoperative creatinine level, and postoperative need for prolonged respiratory support.
Iglezias
Jose Carlos Rossini
JC
INCOR, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. dcirossini@incor.usp.br
Dallan
Luis Alberto Oliveira
LA
Lourenção
Artur
A
Celullare
Alex Luiz
AL
Pereira
Raiane
R
Stolf
Noedir Antonio Groppo
NA
D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D048909:Diabetes Complications; D004696:Endocarditis / Q000150:complications; D004812:Epidemiologic Methods; D005112:Extracorporeal Circulation / Q000009:adverse effects*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D009204:Myocardial Revascularization / Q000009:adverse effects* / Q000401:mortality; D011182:Postoperative Care / Q000009:adverse effects* / Q000145:classification; D011300:Preoperative Care / Q000009:adverse effects* / Q000145:classification; D012770:Shock, Cardiogenic / Q000150:complications