title: Synthesis and antimicrobial activity of 4-hydroxy-4-(pyridyl)alk-3-en-2-ones.
abstract: 4-Hydroxy-4-(pyridyl)alk-3-en-2-ones were prepared by base-mediated condensation of ketones with pyridinecarboxylates. Several derivatives show weak antimicrobial activity against Gram-positive and Gram-negative bacteria.
authors.affiliation: Institut für Chemie, Universität Rostock, Rostock, Germany.
authors.forename: Abdolmajid
authors.initials: A
authors.lastname: Riahi
authors.forename: Martina
authors.initials: M
authors.lastname: Wurster
authors.forename: Michael
authors.initials: M
authors.lastname: Lalk
authors.forename: Ulrike
authors.initials: U
authors.lastname: Lindequist
authors.forename: Peter
authors.initials: P
authors.lastname: Langer
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects* / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
chemical_list: D000900:Anti-Bacterial Agents; D007659:Ketones; D011725:Pyridines; C023666:pyridine