[Acute pancreatitis and space-occupying hepatic lesions in a patient with bone marrow transplant due to multiple myeloma].
Patients with multiple myeloma (MM) do not have a higher incidence of acute pancreatitis or pancreatitis of other etiologies than the general population. However, these patients may develop acute pancreatitis, or hyperamylasemia or isolated hyperlipasemia, due to etiologies that are highly infrequent in the absence of hematological disease. Liver involvement is found in 30-50% of patients with MM and mainly manifests as diffuse sinusoidal infiltration and less frequently in the form of nodules. We report the case of a patient who underwent bone marrow transplantation due to MM who showed clinical and laboratory findings compatible with acute pancreatitis of unknown origin, during which the presence of multiple space-occupying hepatic lesions was identified. Based on the results of biopsy, a diagnosis of extramedullary recurrence of MM was established.
Carneros
José Antonio
JA
Servicio de Digestivo, Hospital Universitario de Fuenlabrada, Madrid, España. jcarneros.hflr@salud.madrid.org
Piqueras
Belén
B
Tomás
Esperanza
E
García-Durán
Fernando
F
Ciriza
Constanza
C
Bermejo
Fernando
F
Sánchez-Prudencio
Sandra
S
Valer
Paz
P
Guerra
Iván
I
García-Garzón
Silvia
S
Villa
José Carlos
JC
Rodríguez Agulló
José Luis
JL
D000208:Acute Disease; D000328:Adult; D000681:Amylases / Q000097:blood; D016026:Bone Marrow Transplantation; D006801:Humans; D008049:Lipase / Q000097:blood; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D009101:Multiple Myeloma / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D010195:Pancreatitis / Q000097:blood / Q000209:etiology*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D014463:Ultrasonography
D008049:Lipase; D000681:Amylases