Relationship between periodontal status and HbA1c in nondiabetics.
OBJECTIVE
Many studies have reported an association between diabetes and periodontitis. We analyzed the periodontal status and glycosylated hemoglobin (HbA1c) level in nondiabetic subjects to investigate the relationship between periodontitis and glucose control in nondiabetics.


METHODS
Periodontal status, HbA1c, serum cholesterol, triglyceride, body mass index (BMI), and demographic variables were assessed in 141 Japanese adults. The difference in the HbA1c level was evaluated among subjects according to periodontal status.


RESULTS
After adjusting for age, gender, BMI, and smoking, alcohol, and exercise habits as covariates, the mean HbA1c was significantly elevated with periodontal deterioration (P = 0.023).


CONCLUSIONS
There was a significant relationship between periodontal status and HbA1c levels in nondiabetics.
Hayashida
Hideaki
H
Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan. hide@nagasaki-u.ac.jp
Kawasaki
Koji
K
Yoshimura
Atsutoshi
A
Kitamura
Masayasu
M
Furugen
Reiko
R
Nakazato
Mio
M
Takamura
Noboru
N
Hara
Yoshitaka
Y
Maeda
Takahiro
T
Saito
Toshiyuki
T
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D055113:Chronic Periodontitis / Q000097:blood* / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010512:Periodontal Index; D011795:Surveys and Questionnaires
D005947:Glucose; D006442:Glycated Hemoglobin; D008055:Lipids