title: Acute pancreatitis as the initial presentation in pediatric systemic lupus erythematosus.
abstract: It is exceptionally rare for acute pancreatitis to be the presenting manifestation of childhood systemic lupus erythematosus. We report a 14-year-old girl who presented with a history of fever, generalized rash, arthralgia and abdominal pain. Her serum amylase was 1472U/L and lipase 3316 U/L suggestive of acute pancreatitis. Other investigations revealed pancytopenia, low complement, high 24-hour urinary protein and elevated ANA and dsDNA. She was treated with IV methylprednisone, followed by oral steroids.
authors.affiliation: Departments of Child Health and Rheumatology and Immunology, Christian Medical College, Vellore 632004, India.
authors.forename: Winsley
authors.initials: W
authors.lastname: Rose
authors.forename: Mammen M
authors.initials: MM
authors.lastname: Puliyel
authors.forename: Prabhakar D
authors.initials: PD
authors.lastname: Moses
authors.forename: Debasis
authors.initials: D
authors.lastname: Danda
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000293:Adolescent; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D010195:Pancreatitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone