Bioavailability of polycyclic aromatic hydrocarbons (PAHs) from soil and hay matrices in lactating goats.
This experiment was aimed at determining the bioavailability of three polycyclic aromatic hydrocarbons (PAHs) in goats: phenanthrene, pyrene, and benzo[a]pyrene. A Latin square design procedure was carried out involving three alpine lactating goats and three PAH-contaminated matrices (soil, hay, and oil as a control). Milk and urine samples were collected to assess PAH and hydroxy-PAH excretion kinetics and to compare the carry-over rates for the different matrices. PAHs were found to be excreted mainly in urine; metabolite concentrations were about 20 times higher in urine than in milk. 1-Hydroxypyrene was the major metabolite in both body fluids (8000 ng/mL urine and 450 ng/mL milk); it may be considered as a valuable indicator of the ruminant exposure to PAHs. Apparent absorption of PAHs estimated by the metabolite excretion in urine and milk reached 34% for pyrene from soil, and the bioavailability of soil-bound PAHs was found to be similar to the bioavailability of PAHs from the other matrices.
Costera
Adrian
A
ISTOM, Cergy-Pontoise, France.
Feidt
Cyril
C
Dziurla
Marie-Antoinette
MA
Monteau
Fabrice
F
Le Bizec
Bruno
B
Rychen
Guido
G
D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D005260:Female; D006041:Goats / Q000502:physiology*; D007700:Kinetics; D007774:Lactation; D008892:Milk / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000652:urine; D012987:Soil / Q000032:analysis*; D012989:Soil Pollutants / Q000032:analysis
D011084:Polycyclic Aromatic Hydrocarbons; D012987:Soil; D012989:Soil Pollutants