title: Clinical and microbiologic characteristics of group A streptococcal necrotizing fasciitis in children.
abstract: An increase in the incidence of Group A streptococcal necrotizing fasciitis has recently been observed in Montréal, Canada. Clinical features of children hospitalized for invasive Group A streptococcal infections and various virulence factor genes of the bacteria were concomitantly analyzed. It was determined that varicella and presence of speC gene in group A streptococcal strains were associated with necrotizing fasciitis.
authors.affiliation: Department of Pediatrics, CHU Sainte-Justine, Montréal, Canada.
authors.forename: Philippe
authors.initials: P
authors.lastname: Minodier
authors.forename: Philippe
authors.initials: P
authors.lastname: Bidet
authors.forename: Fabien
authors.initials: F
authors.lastname: Rallu
authors.forename: Bruce
authors.initials: B
authors.lastname: Tapiero
authors.forename: Edouard
authors.initials: E
authors.lastname: Bingen
authors.forename: Philippe
authors.initials: P
authors.lastname: Ovetchkine
mesh_terms: D000704:Analysis of Variance; D001426:Bacterial Proteins / Q000235:genetics; D002644:Chickenpox / Q000150:complications; D002648:Child; D002675:Child, Preschool; D005098:Exotoxins / Q000235:genetics; D019115:Fasciitis, Necrotizing / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011792:Quebec; D012307:Risk Factors; D013290:Streptococcal Infections / Q000175:diagnosis / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D005098:Exotoxins; C027951:erythrogenic toxin