A unique case of trichorionic quadruplet pregnancy after oocyte donation in a patient with Turner's syndrome.
A 26-year old patient with a mosaic (45X/46XX) Turner's syndrome and secondary amenorrhea since the age of 19, was referred to the IVF unit for participation in oocyte donation program. After a complete work up including meticulous cardiological assessment, she had endometrial preparation with a high dose hormonal regimen, and transfer of three embryos derived from donated oocytes. An ongoing trichorionic quadruplet pregnancy was confirmed on ultrasound. The couple was offered fetal reduction to twins at 12 gestational weeks after consultation stressing the risks of a quadruplet pregnancy in general and especially in a patient with Turner's syndrome. No pregnancy or maternal complications were encountered and the patient delivered two healthy babies by lower segment cesarean section after spontaneous rupture of membranes at 36 gestational weeks.
Makrakis
Evangelos
E
Embryo A.R.T. Assisted Reproduction Unit, 194 Alexandras avenue, Athens 11522, Greece. emakrakis@hotmail.com
Papagianni
Vassiliki
V
Deligeoroglou
Efthimios
E
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy*; D018587:Oocyte Donation; D011247:Pregnancy; D018607:Pregnancy Reduction, Multifetal; D011783:Quadruplets; D014424:Turner Syndrome / Q000150:complications*; D014427:Twins; D016216:Ultrasonography, Prenatal