Rational synthesis of tripyrranes.
The rational, chromatography-free synthesis of two regioisomeric 5,10-diaryltripyrranes from pyrrole and aromatic acids has been developed. The strategy is general and should be applicable to a broad range of acids. This methodology was successfully applied to the synthesis of monoprotected dipyrrane. The oxidation of N,N'-bis-mesyltripyrrane under basic conditions led to the formation of both known tripyrrin-1-one and unknown 1-methoxytripyrrin-a fluorescent dye strongly absorbing green light.
Gałeezowski
Michał
M
Institute of Organic Chemistry of the Polish Academy of Sciences, Warsaw, Poland.
Jaźwiński
Jarosław
J
Lewtak
Jan P
JP
Gryko
Daniel T
DT