title: Pulmonary arterial hypertension associated with gastroesophageal reflux in a 2-month-old boy with Down syndrome.
abstract: A case of a 2-month-old Down syndrome infant without structural cardiac anomaly is reported in whom management of gastroesophageal reflux (GER) using duodenal-tube feeding successfully treated pulmonary arterial hypertension (PAH). Based on this case, examination for GER is recommended for infants who present with PAH, especially those with Down syndrome who have no cardiac anomalies.
authors.affiliation: Department of Pediatric Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Seki
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Kato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Masutani
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Hideaki
authors.initials: H
authors.lastname: Senzaki
mesh_terms: D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D004750:Enteral Nutrition; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D007441:Intubation, Gastrointestinal; D008297:Male; D011015:Pneumonia, Aspiration / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D011859:Radiography; D016896:Treatment Outcome