Skin as an endocrine organ: implications for its function.
Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies.
Slominski
Andrzej
A
Department of Pathology and Laboratory Medicine, University of Tennessee HSC, Memphis, TN, USA.
Wortsman
Jacobo
J
Paus
Ralf
R
Elias
Peter M
PM
Tobin
Desmond J
DJ
Feingold
Kenneth R
KR