title: Neuropsychiatric disorders: Shared genetics of bipolar disorder and schizophrenia.
abstract: Bipolar disorder and schizophrenia share common clinical features, and antipsychotic medications can treat both conditions effectively. An assessment of 73,929 people with bipolar disorder and/or schizophrenia from a Swedish registry found evidence that the two disorders also share more than half of their genetic determinants.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA. jpotash@jhmi.edu
authors.forename: James B
authors.initials: JB
authors.lastname: Potash
authors.forename: O Joseph
authors.initials: OJ
authors.lastname: Bienvenu
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*; D005828:Genetics, Population; D055106:Genome-Wide Association Study / Q000379:methods; D006801:Humans; D008957:Models, Genetic; D012559:Schizophrenia / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*
chemical_list: D014150:Antipsychotic Agents