title: [Are there any predictive factors for successful intracytoplasmic sperm injection. Statical analysis of 339 cycles].
abstract: BACKGROUND
  Intracytoplasmic sperm injection (ICSI) outcome is tightly depinding of male and female factors. The assesment of several clinical and laboratory parameters may predict results of ICSI.
  
  
  OBJECTIVE
  This study aimed at investigation wich parameter(s) may predict successful intracytoplamic sperm injection for infertility.
  
  
  METHODS
  We restrospectively analysed patients who had intracytoplasmic sperm injection for male or female factor infertility. The clinical and laboratory factors that influenced the fertilization, pregnancy and implantation rates were also analysed. Three hundred and thirty nine cycles in 269 couples were analysed. Women's age, etiology of infertility, duration of infertility, number of retrived oocyts, sperm parametres and number of transferred embryos were evaluated.
  
  
  RESULTS
  Optimal pregnancy rates were observed in women aged 25-35 years, with gradual decline with advanced age (p=0.049). The pregnancy/transfer rate was statistically depending of, the numbre of retrieved oocytes (p<0.001) and the numbre of transferred embryos (p<0.001). However, transferring more than three embryos was no significatively superior to two or three. Etiology of infertility had no influence in fertilization and pregnancy, but may predict the implantation rate (p=0.042). The duration of infertility was of no value in predecting the fertilization, implantation or pregnancy rates, and neither seam's to be the sperm parameters.
  
  
  CONCLUSIONS
  The only statitically significant variables of ICSI outcome were women partner's age, numbre of retrived oocytes and numbre of transferred embryos.
authors.affiliation: Centre de PMA, Service de gynécologie obstétrique et de médecine de la reproduction, Hôpital Aziza Othmnana de Tunis, Tunis, Tunisie.
authors.forename: Moez
authors.initials: M
authors.lastname: Kdous
authors.forename: Fethi
authors.initials: F
authors.lastname: Zhioua
authors.forename: Anis
authors.initials: A
authors.lastname: Chaker
authors.forename: Anis
authors.initials: A
authors.lastname: Fadhlaoui
authors.forename: Monia
authors.initials: M
authors.lastname: Ferchiou
authors.forename: Sadok
authors.initials: S
authors.lastname: Meriah
mesh_terms: D000328:Adult; D005260:Female; D005544:Forecasting; D006801:Humans; D011247:Pregnancy / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000706:statistics & numerical data*; D055815:Young Adult