title: Stem cell potential of the mammalian gonad.
abstract: Stem cells have enormous potential for therapeutic application because of their ability to self-renew and differentiate into different cell types. Gonads, which consist of somatic cells and germ cells, are the only organs capable of transmitting genetic materials to the offspring. Germ-line stem cells and somatic stem cells have been found in the testis; however, the presence of stem cells in the ovary remains controversial. In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research.
authors.affiliation: Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.
authors.forename: Chia-Feng
authors.initials: CF
authors.lastname: Liu
authors.forename: Ivraym
authors.initials: I
authors.lastname: Barsoum
authors.forename: Rupesh
authors.initials: R
authors.lastname: Gupta
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Hofmann
authors.forename: Humphrey Hung-Chang
authors.initials: HH
authors.lastname: Yao
mesh_terms: D005260:Female; D005854:Germ Cells / Q000166:cytology*; D006066:Gonads / Q000166:cytology*; D006801:Humans; D008297:Male; D013234:Stem Cells / Q000166:cytology*