title: Degree of risk related to procedures performed in conjunction with surgical myocardial revascularization in octogenarians.
abstract: OBJECTIVE
  We determined the degree of risk produced by the association of other surgical procedures with surgical myocardial revascularization in octogenarian patients and identified the risk factors that best explain hospital mortality.
  
  
  METHODS
  This study was an observational analytical historical cohort study involving octogenarians operated on at our institution between January 1, 2000 and January 1, 2005. We stratified the objective population as follows: Group 1 comprised octogenarians revascularized without associated procedures, and Group 2 comprised octogenarians revascularized with associated procedures. Statistical analyses included the t test for independent samples and multiple logistic regression analysis. Significance was accepted with an alpha error of 5%.
  
  
  RESULTS
  Univariate analyses revealed the following clinical and statistically significant variables: hospital mortality (P=0.002), diabetes mellitus (P=0.017), preoperative endocarditis (P=0.001), cardiogenic shock (P=0.019), use of an intra-aortic balloon pump (P=0.026), preoperative risk score (Parsonnet), P<0.001, procedure associated with revascularization (P<0.001), medium number of affected coronary arteries (P<0.001), use of extracorporeal circulation (P<0.001), time of extracorporeal circulation (P<0.001), number of distal anastomoses (P=0.002), graft type (P<0.001), postoperative breathing support (P<0.001), stroke (P<0.001), infection (P=0.002), creatinine level (P=0.018), and quality of life score (P=0.050).
  
  
  CONCLUSIONS
  In octogenarian patients, the need for a procedure associated with surgical myocardial revascularization produces an absolute increase in hospital mortality risk of 45%. The variables that contributed to hospital mortality were preoperative endocarditis, preoperative cardiogenic shock, the use of extracorporeal circulation, the length of time of extracorporeal circulation, postoperative creatinine level, and postoperative need for prolonged respiratory support.
authors.affiliation: INCOR, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. dcirossini@incor.usp.br
authors.forename: Jose Carlos Rossini
authors.initials: JC
authors.lastname: Iglezias
authors.forename: Luis Alberto Oliveira
authors.initials: LA
authors.lastname: Dallan
authors.forename: Artur
authors.initials: A
authors.lastname: Lourenção
authors.forename: Alex Luiz
authors.initials: AL
authors.lastname: Celullare
authors.forename: Raiane
authors.initials: R
authors.lastname: Pereira
authors.forename: Noedir Antonio Groppo
authors.initials: NA
authors.lastname: Stolf
mesh_terms: D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D048909:Diabetes Complications; D004696:Endocarditis / Q000150:complications; D004812:Epidemiologic Methods; D005112:Extracorporeal Circulation / Q000009:adverse effects*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D009204:Myocardial Revascularization / Q000009:adverse effects* / Q000401:mortality; D011182:Postoperative Care / Q000009:adverse effects* / Q000145:classification; D011300:Preoperative Care / Q000009:adverse effects* / Q000145:classification; D012770:Shock, Cardiogenic / Q000150:complications