"Smart dust" biosensors powered by biomolecular motors.
The concept of a microfabricated biosensor for environmental and biomedical monitoring applications which is composed of environmentally benign components is presented. With a built-in power source (the biological fuel ATP) and driven by biological motors (kinesin), sensing in the microdevice can be remotely activated and the presence of a target molecule or toxin remotely detected. The multifaceted progress towards the realization of such a device is described.
Bachand
George D
GD
Center for Integrated Nanotechnologies, Sandia National Laboratories, Albuquerque, NM 87185, USA.
Hess
Henry
H
Ratna
Banahalli
B
Satir
Peter
P
Vogel
Viola
V
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005240:Feasibility Studies; D016547:Kinesins / Q000378:metabolism*; D055616:Microtechnology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013997:Time Factors
D016547:Kinesins