[Seizure triggered by benzodiazepine receptor antagonist].
Flumazenil is a benzodiazepine antagonist. It is widely used as an antidote in comatose patients suspected of having ingested a benzodiazepine overdose. Flumazenil is known to induce cardiac arythmias and seizures, in part because of drug interactions. We present a 75-year-old woman, who was brought to the Emergency Department with a drug overdose following a suicide attempt. She developed generalized seizures shortly after the administration of flumazenil.
Pedersen
Lars Møller
LM
Gentofte Hospital, Anaestesiologisk Afdeling, Rigshospitalet. larsmoellerp@gmail.com
Petersen
Morten
M
Søndergaard
Inger
I
D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning*; D000931:Antidotes / Q000008:administration & dosage / Q000009:adverse effects*; D062787:Drug Overdose; D005260:Female; D005442:Flumazenil / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D012640:Seizures / Q000139:chemically induced*; D013406:Suicide, Attempted
D000929:Antidepressive Agents, Tricyclic; D000931:Antidotes; D005442:Flumazenil