Mesotherapy for benign symmetric lipomatosis.
BACKGROUND
Benign symmetric lipomatosis, also known as Madelung disease, is a rare disorder characterized by fat distribution around the shoulders, arms, and neck in the context of chronic alcoholism. Complete excision of nonencapsulated lipomas is difficult. However, reports describing conservative therapeutic measures for lipomatosis are rare.


METHODS
The authors present the case of a 42-year-old man with a diagnosis of benign symmetric lipomatosis who had multiple, large, symmetrical masses in his neck. Multiple phosphatidylcholine injections in the neck were administered 4 weeks apart, a total of seven times to achieve lipolysis.


RESULTS
The patient's lipomatosis improved in response to the injections, and he achieved good cosmetic results.


CONCLUSIONS
Intralesional injection, termed mesotherapy, using phosphatidylcholine is a potentially effective therapy for benign symmetric lipomatosis that should be reconsidered as a therapeutic option for this disease.
Hasegawa
Toshio
T
Department of Dermatology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan. t-hase@med.juntendo.ac.jp
Matsukura
Tomoyuki
T
Ikeda
Shigaku
S
D000328:Adult; D006801:Humans; D007267:Injections; D008069:Lipomatosis, Multiple Symmetrical / Q000188:drug therapy* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010713:Phosphatidylcholines / Q000627:therapeutic use*
D010713:Phosphatidylcholines