Regioselective hydroformylation of sulfonamides using a scaffolding ligand.
A highly regioselective hydroformylation of allylic sulfonamides has been developed by employing a catalytic directing group. The reaction tolerates a wide range of electronically and sterically modified olefins, and only 10% of the scaffolding ligand is required to effectively control the regioselectivity.
Worthy
Amanda D
AD
Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.
Gagnon
Moriah M
MM
Dombrowski
Michael T
MT
Tan
Kian L
KL