title: Three-dimensional reconstructive analysis of intracytoplasmic lumina found in ependymomas.
abstract: Three-dimensional reconstructive analyses revealed that the intracytoplasmic lumina found in ependymomas were actually formed by subsidence of an extracellular membrane, resembling a volcano. This finding was compatible with cytologic and electron microscopic findings. In addition, there were many tiny thorns resembling a holly leaf on the extracellular membrane, such that cilia and microvilli on the cellular membrane discontinued cell-to-cell tight junctions.
authors.affiliation: Department of Pathology and Clinical Cytology, Mitsubishi Chemical Medience, Itabashi-ku, Tokyo 174-0051, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Fukudome
authors.forename: Eiji
authors.initials: E
authors.lastname: Ohno
authors.forename: Mamoru
authors.initials: M
authors.lastname: Mochizuki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Eguchi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kojima
mesh_terms: D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D003593:Cytoplasm / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000648:ultrastructure; D004806:Ependymoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed