title: Antimicrobial activity and chemical composition of Senecio sandrasicus on antibiotic resistant staphylococci.
abstract: The antimicrobial activity of hexane, chloroform, ethyl acetate and ethanol extracts of the aerial parts of S. sandrasicus P.H.Davis (Asteraceae), endemic to Sandras mountain (Turkey), were determined. The antimicrobial activity of the extracts on microorganisms including multi-resistant staphylococci were evaluated using the disc diffusion method. The strains of multi-resistant staphylococci and the other standart bacteria were inhibited by some extracts. The volatile organic compouds of S. sandrasicus was determined by Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS). The major compounds of hexane extract were aromadendrene oxide 2 (13.3%), spathulenol (12.5%) and beta-caryophylene (11.8%), respectively.
authors.affiliation: Department of Biology, Faculty of Science and Arts, Mugla University, 48121 Kotekli-Mugla, Turkey. ayselugur@hotmail.com
authors.forename: Aysel
authors.initials: A
authors.lastname: Ugur
authors.forename: Nurdan
authors.initials: N
authors.lastname: Sarac
authors.forename: M Emin
authors.initials: ME
authors.lastname: Duru
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D012674:Senecio / Q000737:chemistry*; D013210:Staphylococcus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts