Acute lymphoblastic leukaemia with unusual chromosomal abnormality: t(3;9) (p21;p13), del(10p12) [13].
We report a case of pre-B acute lymphoblastic leukaemia with an unusual translocation between chromosome 3 and 9, with del(10p12) [13]. The diagnosis at presentation was made by the morphology, cytochemistry and immunophenotyping. Cytogenetic analysis was also done at presentation. To the best of our knowledge and after literature search this appears to be a rare cytogenetic abnormality in ALL.
Dhingra
Bhavna
B
Department of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India. drbdhingra@yahoo.com
Bhargava
Rahul
R
Mishra
Pravas
P
D000293:Adolescent; D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10; D002893:Chromosomes, Human, Pair 3; D002899:Chromosomes, Human, Pair 9; D006801:Humans; D007621:Karyotyping; D015448:Leukemia, B-Cell / Q000235:genetics*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D014178:Translocation, Genetic