title: Immune thrombocytopenic purpura among the children attending at two teaching hospitals.
abstract: The presenting features, diagnostic evaluation, seasonal variation and management performed in 110 children with immune thrombocytopenic purpura (ITP) attending at two tertiary level hospitals were evaluated. A peak incidence of children with ITP was observed during the month of June, July and the first step was found in May and lowest in the month of October to December. Mean initial platelet count was 65.5 x 10(9)/L. 35 patients with ITP did not require any treatment who were kept under observation and the rest 75 children who were admitted to hospital given platelet count enhancing treatment- intravenous immunoglobulin in 9, corticosteroids in 60 or both in 6 children with ITP. Intracranial hemorrhages were noticed in two children with ITP. So, this study suggests that ITP had special predilection during summer season and the least in winter along with variable approaches to management of these children.
authors.affiliation: Department of Pediatric Hematology and Oncology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh.
authors.forename: Md Golam
authors.initials: MG
authors.lastname: Hafiz
authors.forename: M A
authors.initials: MA
authors.lastname: Mannan
authors.forename: Syed Khairul
authors.initials: SK
authors.lastname: Amin
authors.forename: Afiqul
authors.initials: A
authors.lastname: Islam
authors.forename: Fazlur
authors.initials: F
authors.lastname: Rahman
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D017677:Age Distribution; D001459:Bangladesh / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006784:Hospitals, Teaching / Q000706:statistics & numerical data*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D015994:Incidence; D007223:Infant; D008297:Male; D010976:Platelet Count; D011446:Prospective Studies; D011696:Purpura, Thrombocytopenic / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology; D012307:Risk Factors; D012621:Seasons; D011795:Surveys and Questionnaires
chemical_list: D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous