title: Synthesis of 2,3-dihydroquinolin-4(1H)-ones through catalytic metathesis of o-alkynylanilines and aldehydes.
abstract: SbF5-MeOH catalytic system efficiently promotes the alkyne-carbonyl metathesis of o-alkynylaniline derivatives and aldehydes to afford 2,3-disubstituted dihydroquinolinones in moderate to high yields with high trans-selectivity.
authors.affiliation: Laboratory of Organic Reaction Chemistry, Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan. akio-sai@ac.shoyaku.ac.jp
authors.forename: Akio
authors.initials: A
authors.lastname: Saito
authors.forename: Jun
authors.initials: J
authors.lastname: Kasai
authors.forename: Yu
authors.initials: Y
authors.lastname: Odaira
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Fukaya
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hanzawa
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D000965:Antimony / Q000737:chemistry*; D002384:Catalysis; D005459:Fluorides / Q000737:chemistry*; D000432:Methanol / Q000737:chemistry*; D015394:Molecular Structure; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C545227:2,3-dihydroquinolin-4(1H)-one; D000447:Aldehydes; D000480:Alkynes; D000814:Aniline Compounds; D015363:Quinolones; C529140:antimony pentafluoride; D000965:Antimony; D005459:Fluorides; D000432:Methanol