Determination of thioglycolic acid in hair-waving products by disposable electrochemical sensor coupled with high-performance liquid chromatography.
A disposable electrochemical sensor coupled with high-performance liquid chromatography (HPLC) was developed for the determination of thioglycolic acid (TGA) in commercial hair-waving products. The quantitative determination of TGA was first investigated by using a preanodized (*) screen-printed carbon electrode (SPCE*). Because of the electrocatalytic effect of the SPCE*, the peak potential (Epa) was shifted less positively as the current magnitude increased. HPLC was used in this study to eliminate interference from the matrix of real samples. The effects of various parameters, such as preanodization potential, preanodization time, solution pH, detection potential, and mobile phase, were studied in detail. Under optimized conditions, the linear range for TGA is up to 20 ppm, correlation coefficient (r2) = 0.998, with a detection limit of 0.042 ppm (signal-to-noise ratio = 3). The practical application of the proposed method was demonstrated by the determination of TGA concentration in commercial hair-waving products.
Zen
Jyh-Myng
JM
National Chung Hsing University, Department of Chemistry, Taichung 402, Taiwan.
Yang
Hsueh-Hui
HH
Chiu
Mei-Hsin
MH
Chen
Yu-Ju
YJ
Shih
Ying
Y
D002244:Carbon; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods* / Q000706:statistics & numerical data; D004566:Electrodes; D006203:Hair Preparations / Q000032:analysis* / Q000633:toxicity; D006801:Humans; D013864:Thioglycolates / Q000032:analysis* / Q000633:toxicity
D006203:Hair Preparations; D013864:Thioglycolates; D002244:Carbon