title: Assessing the skeleton in children and adolescents with disabilities: avoiding pitfalls, maximising outcomes. A guide for the general paediatrician.
abstract: Assessment of bone health of a young person with a severe disability is complex. Age of onset of disability, degree of physical limitation, nutritional status, calcium and vitamin D intake and pubertal progress all contribute to adult outcomes. Concomitant medical conditions may further adversely affect bone accrual. Bone quality, until growth is complete, must be interpreted in light of growth, height and puberty. For those children and adolescents who have disabilities where weight bearing is limited, satisfactory and reproducible measurements of bone density may be impossible to obtain. Fracture risk is dependent on the degree of immobilisation and on bone quality at any age. Meeting the goal of reducing extent and complications of adult osteoporosis is dependent upon an understanding of the nature and contribution of individual components of bone accrual, so that interventions can be appropriately targeted to optimise outcomes.
authors.affiliation: Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, Victoria, Australia. margaret.zacharin@rch.org.au
authors.forename: Margaret
authors.initials: M
authors.lastname: Zacharin
mesh_terms: D000293:Adolescent; D000328:Adult; D015519:Bone Density / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000503:physiopathology*; D001842:Bone and Bones / Q000503:physiopathology*; D002648:Child; D019988:Children with Disabilities; D006233:Persons with Disabilities; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D010024:Osteoporosis; D010372:Pediatrics; D012307:Risk Factors