title: [Churg-Strauss syndrome: diagnostic and therapeutic challenge - a case report].
abstract: This report describes the Churg-Strauss syndrome (CSS) in a 23-year-old asthmatic man treated with a leukotriene antagonists-montelukast. The Churg-Strauss syndrome is now defined as one of the ANCA-associated vasculitis and is characterised by eosinophilia, asthma, chronic sinusitis, cardiomyopathy, pulmonary infiltrates, cutaneous vasculitis, gastrointestinal complaints and a muliplex neuropathy. The pathogenesis is not clear, but it has been reported in patients treated with leukotriene antagonists. We describe a case of CSS with severe pulmonary and cardiovascular complications.
authors.affiliation: Klinika Chorób Wewnetrznych i Diabetologii, Uniwersytet Medyczny w Poznaniu. wizus@op.pl
authors.forename: Dorota
authors.initials: D
authors.lastname: Pisarczyk-Wiza
authors.forename: Bogna
authors.initials: B
authors.lastname: Wierusz-Wysocka
mesh_terms: D000085:Acetates / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000276:immunology* / Q000628:therapy; D003521:Cyclopropanes; D006801:Humans; D020024:Leukotriene Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D010493:Pericarditis / Q000150:complications / Q000188:drug therapy*; D011014:Pneumonia / Q000150:complications / Q000188:drug therapy*; D011804:Quinolines / Q000009:adverse effects* / Q000627:therapeutic use; D013440:Sulfides
chemical_list: D000085:Acetates; D003521:Cyclopropanes; D020024:Leukotriene Antagonists; D011804:Quinolines; D013440:Sulfides; C093875:montelukast