title: Obesity and metabolic disease.
abstract: Obesity independently increases the risk of developing diabetes 10-fold compared with that for patients who are normal weight. Overweight patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) should be given counseling on weight loss of 5% to 10% of body weight as well as on increasing physical activity to at least 150 min/wk to prevent progression to diabetes. American Diabetes Association (ADA) recommends screening patients older than 45 years with a body mass index (BMI) greater than or equal to 25 for diabetes with fasting glucose every 3 years. Testing should be considered at a younger age or performed more frequently for those who are overweight and have 1 or more risk factors for diabetes.
authors.affiliation: Curtis W. and Ann H. Long Department of Family and Community Medicine, University of Missouri, Columbia, MO 65212, USA. koopmanr@health.missouri.edu
authors.forename: Richelle J
authors.initials: RJ
authors.lastname: Koopman
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Swofford
authors.forename: Mark N
authors.initials: MN
authors.lastname: Beard
authors.forename: Susan E
authors.initials: SE
authors.lastname: Meadows
mesh_terms: D015992:Body Mass Index; D001837:Body Weights and Measures; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000517:prevention & control; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D024821:Metabolic Syndrome / Q000150:complications* / Q000517:prevention & control; D009765:Obesity / Q000150:complications*; D011236:Prediabetic State; D015995:Prevalence; D012307:Risk Factors