Effects of cardiac rehabilitation in patients with metabolic syndrome after coronary artery bypass grafting.
BACKGROUND
Cardiac rehabilitation (CR) has numerous beneficial effects, including the modification of coronary risk factors and improvement of the prognosis, in patients with coronary artery disease (CAD). Limited data are available regarding the effects of CR on the physical status and risk factors in patients with metabolic syndrome (MetS) after coronary artery bypass grafting (CABG).


RESULTS
We enrolled 32 patients with MetS after CABG, who participated in a supervised CR program for 6 months. Metabolic parameters, blood chemistry, exercise tolerance, and muscle strength of the thigh were measured before and after CR. After CR: (1) the body mass index, waist circumference, and fat weight significantly decreased; (2) peak V O(2) and anaerobic threshold were significantly increased; (3) isokinetic peak torques of knee extensor and flexor muscles significantly increased; (4) metabolic scoring defined by the number of the modified Adult Treatment Panel criteria of the US National Cholesterol Education Program was significantly improved; (5) serum concentration of high-sensitivity C-reactive protein also significantly decreased.


CONCLUSIONS
These results suggest that CR might be useful for patients with MetS after CABG.
Onishi
Tomo
T
Sports Clinic, Juntendo University Hospital, Tokyo, Japan.
Shimada
Kazunori
K
Sunayama
Satoshi
S
Ohmura
Hirotoshi
H
Sumide
Takahiro
T
Masaki
Yoshiyuki
Y
Fukao
Kosuke
K
Nishitani
Miho
M
Kume
Atsumi
A
Sato
Hiroyuki
H
Naito
Hisashi
H
Kawai
Sachio
S
Amano
Atsushi
A
Daida
Hiroyuki
H
D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose; D001837:Body Weights and Measures; D002097:C-Reactive Protein / Q000032:analysis; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000150:complications / Q000534:rehabilitation* / Q000601:surgery; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis / Q000534:rehabilitation*; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors
D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids; D002097:C-Reactive Protein