title: Advances in the basic and clinical science of migraine.
abstract: Migraine continues to be an elephant in the room of medicine: massively common and a heavy burden on patients and their healthcare providers, yet the recipient of relatively little attention for research, education, and clinical resources. Its visibility is gradually increasing, however, as advances in genetics, imaging, epidemiology, and pharmacology produce a more definitive understanding of the condition, and identify more specific and effective treatments. Rapid evolution of concepts regarding its prevalence, pathophysiology, and clinical management is leading to growing recognition of migraine as a fundamentally important disorder of the nervous system.
authors.affiliation: Department of Neurology, David Geffen School of Medicine at University of California-Los Angeles, 635 Charles Young Drive, Los Angeles, CA 90095, USA. acharles@ucla.edu
authors.forename: Andrew
authors.initials: A
authors.lastname: Charles
mesh_terms: D035843:Biomedical Research; D002986:Clinical Trials as Topic; D018450:Disease Progression; D054092:Foramen Ovale, Patent / Q000503:physiopathology; D006801:Humans; D008881:Migraine Disorders / Q000235:genetics / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D012678:Sensation Disorders / Q000209:etiology