Ras and Nox: Linked signaling networks?
Both Ras and Nox represent ancient gene families which control a broad range of cellular responses. Both families mediate signals governing motility, differentiation, and proliferation, and both inhabit overlapping subcellular microdomains. Yet little is known of the precise functional relationship between these two ubiquitous families. In this review, we examine the interface where these two large fields meet.
Wu
Ru Feng
RF
Division of Pulmonary and Critical Care, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Terada
Lance S
LS
D000818:Animals; D006801:Humans; D019255:NADPH Oxidases / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D018631:ras Proteins / Q000378:metabolism*
D019255:NADPH Oxidases; D018631:ras Proteins