Human parechovirus-3 infection: emerging pathogen in neonatal sepsis.
Human parechovirus-3 (HPeV-3) is an emerging pathogen that has been described as a cause of neonatal sepsis. Human parechoviruses are a family of viruses closely related to enteroviruses; however, enteroviral PCR will not detect HPeVs. We present clinical details of neonatal meningoencephalitis and hepatitis-coagulopathy syndrome caused by HPeV-3 infection.
Levorson
Rebecca E
RE
Division of Infectious Diseases, Children's National Medical Center, Washington, DC, USA. rlevorso@cnmc.org
Jantausch
Barbara A
BA
Wiedermann
Bernhard L
BL
Spiegel
Hans M L
HM
Campos
Joseph M
JM
D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000821:virology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D030061:Parechovirus / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D010850:Picornaviridae Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D016133:Polymerase Chain Reaction; D018805:Sepsis / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology
D000998:Antiviral Agents; D000212:Acyclovir