The effects of topical levobupivacaine on morbidity in pediatric tonsillectomy patients.
OBJECTIVE
To reduce the post-tonsillectomy morbidity by swab soaked with 5 ml levobupivacaine hydroclorur (25 mg/10 ml).


METHODS
A double-blind prospective randomized controlled clinical study.


METHODS
In this randomized double-blind study in group I (30 children, mean age 7.5+/-2.6) we tightly packed swab soaked with 5 ml levobupivacaine hydroclorur (25mg/10 ml) and in group II (21 children, mean age 7.9+/-3.7) we used 5 ml saline swabs into each of the two tonsillar fossae after tonsillectomy for 5 min. We used McGrath's face scale to compare the two groups in respect of pain control.


RESULTS
There was statistically significant pain relieving effect in the levobupivacaine group in the first 24h (p<0.05). But after 24h pain relieving effect of levobupivacaine was not significant (p>0.05). We did not see any serious complications for both groups. Postoperative morbidity mean results (nausea, vomiting, fever, bleeding, halitosis and ear pain) were not statistically different between the two groups (p>0.05).


CONCLUSIONS
Topical levobupivacaine seems to be a safe and easy medication for postoperative pain control in pediatric tonsillectomy patients.
Yilmaz
Süleyman
S
Duzce University, Duzce Medical Faculty, Department of ENT and Head & Neck Surgery, Duzce, Turkey. dryilmazsuleyman@yahoo.com
Demiraran
Yavuz
Y
Akkan
Nermin
N
Yaman
Hüseyin
H
Iskender
Abdulkadir
A
Güçlü
Ender
E
Oztürk
Ozcan
O
D000287:Administration, Topical; D000293:Adolescent; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage / Q000031:analogs & derivatives; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D000077554:Levobupivacaine; D008297:Male; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D020250:Postoperative Nausea and Vomiting / Q000209:etiology / Q000517:prevention & control; D014068:Tonsillectomy / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
D000779:Anesthetics, Local; D000077554:Levobupivacaine; D002045:Bupivacaine