title: Early congenital syphilis with isolated bone involvement: a case report.
abstract: Congenital syphilis is the oldest recognized congenital infection and still represents a serious healthcare problem in the 21st century. It is important to be fully informed regarding the early diagnosis and treatment of congenital syphilis to prevent its devastating complications leading to death. In this manuscript, we report a newborn infant with unusual clinical findings of congenital syphilis such as a non-fluctuant mass surrounding the left calf. She did not have any additional system involvement such as hepatic or skin involvement or lymph nodes. To our best knowledge, there are only a few case reports presented with isolated bone involvement. This case demonstrates that congenital syphilis should be considered in neonates with bone fractures, lytic bone lesions and periostitis.
authors.affiliation: Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Didem
authors.initials: D
authors.lastname: Armangil
authors.forename: Fuat Emre
authors.initials: FE
authors.lastname: Canpolat
authors.forename: Sule
authors.initials: S
authors.lastname: Yiğit
authors.forename: Haci Ahmet
authors.initials: HA
authors.lastname: Demir
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ceyhan
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005360:Fibula / Q000000981:diagnostic imaging / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008279:Magnetic Resonance Imaging; D010400:Penicillin G / Q000627:therapeutic use; D010522:Periostitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D011859:Radiography; D013590:Syphilis, Congenital / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D014210:Treponema pallidum; D014463:Ultrasonography
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G