First isolation of Burkholderia tropica from a neonatal patient successfully treated with imipenem.
We report the first case of a human Burkholderia tropica infection. The patient was a premature neonate who had necrotizing enterocolitis with bowel perforation requiring surgical intervention. The stoma care and difficulties in feeding were a chronic problem. At the age of almost 4 months he developed septicemia due to B. tropica. Three consecutive blood cultures grew this organism. The organism was cleared from the blood after a course of imipenem and resolution of post-operative ileus. Our case suggests that environmental and plant pathogens can cause human infection especially in those in an immunocompromised condition.
Deris
Zakuan Zainy
ZZ
Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia. zakuan@kb.usm.my
Van Rostenberghe
Hans
H
Habsah
Hassan
H
Noraida
Ramli
R
Tan
Gin Ceong
GC
Chan
Yean Yean
YY
Rosliza
Abdul Rahman
AR
Ravichandran
Manicham
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D019117:Burkholderia / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D019121:Burkholderia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D017809:Fatal Outcome; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D016867:Immunocompromised Host; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D012307:Risk Factors
D000900:Anti-Bacterial Agents; D015378:Imipenem