NIR fluorescent ytterbium compound for in vivo fluorescence molecular imaging.
We have developed a new NIR fluorescent probe based on an ytterbium(III) (E)-1-(pyridin-2-yl-diazenyl)naphthalen-2-ol (PAN) complex. This probe emits near-infrared luminescence derived from the Yb ion through excitation of the PAN moiety with visible light (lambda(ex)= 530 nm, lambda(em)= 975 nm). The results support the possible utility of the probe for in vivo fluorescence molecular imaging.
Aita
Kazuki
K
Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.
Temma
Takashi
T
Kuge
Yuji
Y
Seki
Koh-ichi
K
Saji
Hideo
H
D005453:Fluorescence; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011789:Quantum Theory; D019265:Spectroscopy, Near-Infrared; D015018:Ytterbium / Q000737:chemistry*
D009942:Organometallic Compounds; D015018:Ytterbium