title: Monoclonal antibodies with orthogonal azaspiracid epitopes.
abstract: Azaspiracid antibodies: Immunization of azaspiracid immunoconjugates has elicited monoclonal antibodies with distinct epitopes on the marine toxin; this will open the way toward azaspiracid diagnostics and the detection of contaminated shellfish before they can enter the food supply.
authors.affiliation: Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Michael O
authors.initials: MO
authors.lastname: Frederick
authors.forename: Sandra
authors.initials: S
authors.lastname: De Lamo Marin
authors.forename: Kim D
authors.initials: KD
authors.lastname: Janda
authors.forename: K C
authors.initials: KC
authors.lastname: Nicolaou
authors.forename: Tobin J
authors.initials: TJ
authors.lastname: Dickerson
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry* / Q000276:immunology / Q000378:metabolism; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000737:chemistry* / Q000378:metabolism; D018796:Immunoconjugates / Q000276:immunology / Q000378:metabolism; D008387:Marine Toxins / Q000032:analysis* / Q000737:chemistry / Q000276:immunology; D051379:Mice; D012758:Shellfish / Q000633:toxicity; D013141:Spiro Compounds / Q000032:analysis* / Q000737:chemistry / Q000276:immunology; D000095702:Polyether Toxins
chemical_list: D000911:Antibodies, Monoclonal; D000939:Epitopes; D018796:Immunoconjugates; D008387:Marine Toxins; D013141:Spiro Compounds; C406592:azaspiracid; D000095702:Polyether Toxins