title: [Invasive aspergillosis of the cavum associated with candidal meningitis].
abstract: Aspergillus fumigatus is a resistant filamentous fungus, common in the environment and pathogenic for human. The most common sites of primary aspergillosis are the maxillary sinus and lungs. Intracranial location is rare and may develop after hematogenous dissemination or contiguity. The invasive pseudotumoral form usually concerns immunodepressed patients. Invasive aspergillosis of the cavum is rare and its diagnosis is difficult. This infection can be fatal because of endocranial involvement and permeabilization of the blood-brain barrier, facilitating other neuromeningeal mycotic infections. We report the case of a 70-year-old diabetic and hypertensive female patient having presented with an invasive aspergillosis of the cavum and endocranial involvement complicated by Candida meningitis.
authors.affiliation: Service de réanimation médicale, hôpital militaire d'instruction Mohammed V, Rabat, Maroc. salah_masson80@hotmail.com
authors.forename: S
authors.initials: S
authors.lastname: Massou
authors.forename: H
authors.initials: H
authors.lastname: Azendour
authors.forename: T
authors.initials: T
authors.lastname: Nebhani
authors.forename: B E
authors.initials: BE
authors.lastname: Lmimouni
authors.forename: B
authors.initials: B
authors.lastname: Azendour
authors.forename: H
authors.initials: H
authors.lastname: Belkhi
authors.forename: C
authors.initials: C
authors.lastname: Haimeur
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000150:complications*; D001232:Aspergillus fumigatus; D002177:Candidiasis / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016921:Meningitis, Fungal / Q000150:complications*