Recent advances in the treatment of acromegaly.
OBJECTIVE
Description of recent outcomes and approaches to the treatment of patients with de-novo and recurrent acromegaly.


RESULTS
Radiosurgery for acromegaly results in a higher likelihood of remission and an earlier time to remission than does conventional radiotherapy. Somatostatin analogs results in control of acromegaly and one half of patients. Combining treatment with pegvisomant and somatostatin analogs results in overall improved quality of life.


CONCLUSIONS
Existing treatments offer patients and their treating physicians opportunities to restore life expectancy to normal and reverse many of the symptoms and signs of acromegaly.
Aghi
Manish
M
California Center for Pituitary Disorders at UCSF, Department of Neurological Surgery, University of California, San Francisco, California, USA.
Blevins
Lewis S
LS
D000172:Acromegaly / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D004359:Drug Therapy, Combination; D019382:Human Growth Hormone / Q000378:metabolism; D006801:Humans; D008017:Life Expectancy; D011788:Quality of Life
D019382:Human Growth Hormone