title: Monkey malaria in humans: a diagnostic dilemma with conflicting laboratory data.
abstract: Plasmodium knowlesi has recently been recognized as the fifth Plasmodium species causing malaria in humans. Diagnosis is difficult morphologically, and currently, available rapid tests have not been comprehensively evaluated with this pathogen. We report a case of P. knowlesi malaria that was confirmed after the initial clue of discordant microscopy and immunochromatographic results, highlighting the importance of molecular diagnostics in cases with the relevant clinical and epidemiologic history.
authors.affiliation: National University Health System, Singapore; Defence Medical and Environmental Research Institute, Singapore. catongwm@yahoo.com
authors.forename: Catherine W M
authors.initials: CW
authors.lastname: Ong
authors.forename: Shir Ying
authors.initials: SY
authors.lastname: Lee
authors.forename: Wee Hong
authors.initials: WH
authors.lastname: Koh
authors.forename: Eng-Eong
authors.initials: EE
authors.lastname: Ooi
authors.forename: Paul A
authors.initials: PA
authors.lastname: Tambyah
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use; D016054:DNA, Protozoan / Q000097:blood / Q000737:chemistry; D006801:Humans; D008288:Malaria / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D008297:Male; D016790:Plasmodium knowlesi / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011319:Primaquine / Q000627:therapeutic use; D012335:RNA, Ribosomal / Q000235:genetics
chemical_list: D000962:Antimalarials; D016054:DNA, Protozoan; D012335:RNA, Ribosomal; D002738:Chloroquine; D011319:Primaquine