Dietary intervention after definitive therapy for localized prostate cancer: results from a pilot study.
BACKGROUND
Diet has been linked to prostate cancer risk. Dietary modification may inhibit prostate cancer progression.


METHODS
As part of a randomized trial, we analyzed the effect of a diet based intervention on 25 prostate cancer patients who had previously undergone surgery or radiation.


CONCLUSIONS
In the intervention arm, vegetable intake increased (p < 0.05), fat intake decreased (p < 0.05), and mean plasma levels of ss-carotene and total carotenoids increased (p < 0.05). In the control arm, there were no significant changes in diet or blood carotenoids. These data support the feasibility of studying dietary interventions as salvage or adjuvant therapy after surgery or radiation for localized prostate cancer.
Parsons
J Kellogg
JK
University of California, San Diego Medical Center, San Diego, CA 92103-8897, USA.
Newman
Vicky A
VA
Mohler
James L
JL
Pierce
John P
JP
Flatt
Shirley
S
Messer
Karen
K
Marshall
James
J
D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000178:diet therapy* / Q000532:radiotherapy / Q000601:surgery; D016896:Treatment Outcome
D017430:Prostate-Specific Antigen