title: Plasma vaporisation of the prostate: initial clinical results.
abstract: BACKGROUND
  Laser vaporisation of the prostate has had a considerable impact in recent years. In an attempt to achieve tissue vaporisation with bipolar high-frequency generators, plasma vaporisation was recently introduced.
  
  
  OBJECTIVE
  To provide the first clinical information on bipolar plasma vaporisation of the prostate for patients with lower urinary tract symptoms (LUTS) due to bladder outlet obstruction (BOO).
  
  
  METHODS
  Thirty patients were included in this prospective bicentre study.
  
  
  METHODS
  All patients underwent bipolar plasma vaporisation with a novel electrode (Olympus Winter & Ibe GmbH, Hamburg, Germany).
  
  
  METHODS
  International Prostate Symptom Score (IPSS), bother score, maximum flow rate (Q(max)), and postvoid residual were evaluated at baseline and at the time of discharge as well as at 1, 3, and 6 mo after the intervention.
  
  
  CONCLUSIONS
  Mean preoperative prostate volume was 59±32 ml (range: 30-170), and mean operating time was 61±26 min (range: 20-140). Besides one reoperation (conventional transurethral prostatectomy) due to persistent obstruction, no major complication occurred intra- or postoperatively and no blood transfusion was required. Catheterisation time averaged 41±35 h (range: 18-192). Transient mild to moderate dysuria was noted in four patients (13%). At 1, 3, and 6 mo, Q(max) increased from 6.6±2.7 ml/s preoperative to 17.3±4.7 ml/s (p<0.01), 18.5±4.6 ml/s (p<0.01), and 18.1±5.0 ml/s (p<0.01), respectively. The IPSS decreased from 20.8±3.6 to 10.4±3.5 (p<0.01), 8.2±2.9 (p<0.01), and 8.1±3.1 (p<0.01), respectively. These data represent a small nonrandomised study cohort with limited follow-up.
  
  
  CONCLUSIONS
  Our initial experience indicates that bipolar plasma vaporisation might be a safe and effective treatment option for patients with LUTS due to BOO. To define the potential role of this novel technique, randomised trials with longer follow-up are mandatory.
authors.affiliation: Department of Urology, University Hospital Munich Grosshadern, Ludwig Maximilians University, D 81377 Munich, Germany. oreich@med.uni-muenchen.de
authors.forename: Oliver
authors.initials: O
authors.lastname: Reich
authors.forename: Boris
authors.initials: B
authors.lastname: Schlenker
authors.forename: Christian
authors.initials: C
authors.lastname: Gratzke
authors.forename: Derya
authors.initials: D
authors.lastname: Tilki
authors.forename: Malte
authors.initials: M
authors.lastname: Riecken
authors.forename: Christian
authors.initials: C
authors.lastname: Stief
authors.forename: Michael
authors.initials: M
authors.lastname: Seitz
authors.forename: Alexander
authors.initials: A
authors.lastname: Bachmann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D053159:Dysuria / Q000209:etiology; D004598:Electrosurgery / Q000009:adverse effects / Q000379:methods*; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012086:Reoperation; D012720:Severity of Illness Index; D013557:Switzerland; D013997:Time Factors; D020728:Transurethral Resection of Prostate; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D014546:Urinary Catheterization; D014563:Urodynamics; D014835:Volatilization