title: Bioavailability of polycyclic aromatic hydrocarbons (PAHs) from soil and hay matrices in lactating goats.
abstract: This experiment was aimed at determining the bioavailability of three polycyclic aromatic hydrocarbons (PAHs) in goats: phenanthrene, pyrene, and benzo[a]pyrene. A Latin square design procedure was carried out involving three alpine lactating goats and three PAH-contaminated matrices (soil, hay, and oil as a control). Milk and urine samples were collected to assess PAH and hydroxy-PAH excretion kinetics and to compare the carry-over rates for the different matrices. PAHs were found to be excreted mainly in urine; metabolite concentrations were about 20 times higher in urine than in milk. 1-Hydroxypyrene was the major metabolite in both body fluids (8000 ng/mL urine and 450 ng/mL milk); it may be considered as a valuable indicator of the ruminant exposure to PAHs. Apparent absorption of PAHs estimated by the metabolite excretion in urine and milk reached 34% for pyrene from soil, and the bioavailability of soil-bound PAHs was found to be similar to the bioavailability of PAHs from the other matrices.
authors.affiliation: ISTOM, Cergy-Pontoise, France.
authors.forename: Adrian
authors.initials: A
authors.lastname: Costera
authors.forename: Cyril
authors.initials: C
authors.lastname: Feidt
authors.forename: Marie-Antoinette
authors.initials: MA
authors.lastname: Dziurla
authors.forename: Fabrice
authors.initials: F
authors.lastname: Monteau
authors.forename: Bruno
authors.initials: B
authors.lastname: Le Bizec
authors.forename: Guido
authors.initials: G
authors.lastname: Rychen
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D005260:Female; D006041:Goats / Q000502:physiology*; D007700:Kinetics; D007774:Lactation; D008892:Milk / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000652:urine; D012987:Soil / Q000032:analysis*; D012989:Soil Pollutants / Q000032:analysis
chemical_list: D011084:Polycyclic Aromatic Hydrocarbons; D012987:Soil; D012989:Soil Pollutants