Solid-state nanopore for detecting individual biopolymers.
Solid-state nanopores have been fabricated and used to characterize single DNA and protein molecules. Here we describe the details on how these nanopores were fabricated and characterized, the nanopore sensing system setup, and protocols of using these nanopores to characterize DNA and protein molecules.
Li
Jiali
J
Department of Physics, University of Arkansas, Fayetteville, AR 72701, USA. jialili@uark.edu
Golovchenko
Jene A
JA
D001704:Biopolymers / Q000032:analysis*; D004247:DNA / Q000032:analysis / Q000737:chemistry; D004867:Equipment Design; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D008970:Molecular Weight; D049329:Nanostructures / Q000648:ultrastructure; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D011506:Proteins / Q000032:analysis; D017655:Silicon Compounds
D001704:Biopolymers; D011506:Proteins; D017655:Silicon Compounds; D004247:DNA; C032734:silicon nitride