HLA-B*1832, a novel B allele was found through high-resolution HLA typing of a Spanish blood donor.
In this paper, we describe the novel human leukocyte antigen (HLA)-B*1832 allele that we found in a female Spanish volunteer blood donor for clinical investigation during her high-resolution HLA typing. The HLA-B typing is B*1801, 1832, and the DNA sequence is homozygous with the exception characterized by a nucleotide exchange 'C' to 'A' at position 505, which, in consequence, replaced arginine at codon 169 (CGC) by serine in the new allele B*1832.
Witter
K
K
Laboratory of Immunogenetics, University Munich, Munich, Germany. klaus.witter@med.uni-muenchen.de
Conrad
H
H
Bernhard
H
H
Albert
T
T
Kauke
T
T
D000483:Alleles; D001483:Base Sequence; D001782:Blood Donors; D005260:Female; D015235:HLA-B Antigens / Q000235:genetics*; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D008403:Mass Screening; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide; D012689:Sequence Homology, Nucleic Acid; D013030:Spain
D015235:HLA-B Antigens