Three-dimensional coregistered optical coherence tomography and line-scanning fluorescence laminar optical tomography.
We present a combined optical coherence tomography (OCT) and line-scanning fluorescence laminar optical tomography (FLOT) system. This hybrid system enables coregistered structural and molecular imaging in 3D with 10-100 microm resolution and millimeter-scale imaging depth. Experimental results on a capillary phantom with fluorescence dye Cy5.5 using an OCT/FLOT imaging system have been demonstrated.
Yuan
Shuai
S
Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA.
Li
Qian
Q
Jiang
James
J
Cable
Alex
A
Chen
Yu
Y
D005453:Fluorescence; D021621:Imaging, Three-Dimensional / Q000379:methods*; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*