N(4)-Methyl-N(4)-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine-ethanol-hydrazine (1/0.865/0.135): hydrogen-bonded ribbons containing four independent ring types.
N(4)-Methyl-N(4)-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine crystallizes from ethanol as a mixed solvate, C(13)H(14)N(6).0.865C(2)H(6)O.0.135N(2)H(4), (I), where the hydrazine has been carried through from the initial preparation. Within the heterocyclic component, the 2-methylphenyl substituent is disordered over two sets of sites. There is an intramolecular C-H...pi(arene) hydrogen bond, which may control the molecular conformation of the heterocycle. The heterocyclic molecules are linked by two independent N-H...N hydrogen bonds in a chain containing two types of R(2)(2)(8) ring. The ethanol component is linked to this chain by a combination of O-H...N and N-H...O hydrogen bonds and the hydrazine component by two N-H...N hydrogen bonds, so generating two R(3)(3)(9) rings and thus forming a ribbon containing four distinct ring types.
Trilleras
Jorge
J
Grupo de Investigación de Compuestos Heterociclícos, Departamento de Química, Universidad de Valle, AA 25360, Colombia.
Quiroga
Jairo
J
Cobo
Justo
J
Glidewell
Christopher
C
D018360:Crystallography, X-Ray; D006834:Hydrazines / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D011743:Pyrimidines / Q000737:chemistry*
D006834:Hydrazines; C543559:N(4)-methyl-N(4)-(2-methylphenyl)-1H-pyrazolo(3,4-d)pyrimidine-4,6-diamine-ethanol-hydrazine; D011743:Pyrimidines