title: Prevalence of cardiomyopathy in apparently healthy cats.
abstract: OBJECTIVE
  To determine the prevalence of cardiomyopathy and the relationship between cardiomyopathy and heart murmurs in apparently healthy cats.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  103 privately owned, apparently healthy domestic cats.
  
  
  METHODS
  Cats were physically and echocardiographically examined by 2 investigators independently. Left ventricular wall thickness was determined via 2-dimensional echocardiography in short-axis and long-axis planes. Left ventricular hypertrophy was identified when end-diastolic measurements of the interventricular septum or posterior wall were > or = 6 mm. Cats with left ventricular hypertrophy but without left ventricular dilatation were considered to have hypertrophic cardiomyopathy (HCM). The associations between heart murmurs and Doppler echocardiographic velocity profiles indicative of dynamic ventricular outflow tract obstruction were evaluated.
  
  
  RESULTS
  Heart murmurs were detected in 16 (15.5%; 95% confidence interval, 9.2% to 24.0%) cats; of these, 5 had cardiomyopathy. Cardiomyopathy was also identified in 16 (15.5%; 95% confidence interval, 9.2% to 24.0%) cats; 15 had HCM, and 1 had arrhythmogenic right ventricular cardiomyopathy. Of the cats with HCM, 11 had segmental left ventricular hypertrophy, 3 had diffuse left ventricular hypertrophy, and 1 had borderline left ventricular hypertrophy with marked systolic anterior motion of the mitral valve. Sensitivity and specificity of auscultatory detection of a heart murmur for diagnosing cardiomyopathy were 31% and 87%, respectively. Echocardiographic evidence of late systolic acceleration within ventricular outflow tracts was associated with the existence of a heart murmur.
  
  
  CONCLUSIONS
  Cardiomyopathy was common in the healthy cats evaluated in this study. In apparently healthy cats, detection of a heart murmur is not a reliable indicator of cardiomyopathy.
authors.affiliation: Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute, Blacksburg, VA 24061, USA.
authors.forename: Christopher F
authors.initials: CF
authors.lastname: Paige
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Abbott
authors.forename: François
authors.initials: F
authors.lastname: Elvinger
authors.forename: R Lee
authors.initials: RL
authors.lastname: Pyle
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000453:epidemiology; D002415:Cats; D004452:Echocardiography / Q000662:veterinary; D005260:Female; D006337:Heart Murmurs / Q000662:veterinary; D008297:Male; D015995:Prevalence