Identification of a novel HLA-Cw*08 variant allele, Cw*0821.
The novel human leukocyte antigen-Cw*0821 allele differs from the closest allele Cw*080101 by single nucleotide change at genomic DNA nucleotide 419 A>G (codon73 ACT>GCT) in exon 2, which results in an amino acid change Thr73Ala.
Wang
D-M
DM
Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China.
Deng
Z-H
ZH
D000409:Alanine / Q000378:metabolism; D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D005091:Exons; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D015236:HLA-C Antigens / Q000235:genetics*; D006239:Haplotypes; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011933:Reagent Kits, Diagnostic; D017422:Sequence Analysis, DNA / Q000295:instrumentation / Q000379:methods; D012689:Sequence Homology, Nucleic Acid; D013234:Stem Cells / Q000166:cytology; D009626:Terminology as Topic; D014019:Tissue Donors
D017931:DNA Primers; D015236:HLA-C Antigens; D011933:Reagent Kits, Diagnostic; D000409:Alanine