title: Adjunctive diagnostic value of MRI in the breast radial scar.
abstract: OBJECTIVE
  We sought to identify breast magnetic resonance imaging (MRI) criteria capable of influencing the differential diagnosis between radial scars related to benign proliferative disease and those associated with breast cancer with a view to proposing breast MRI as a promising and cost-effective modality to be carried out between mammography and surgical biopsy.
  
  
  METHODS
  From 1998 to June 2006, we studied 20 patients with a focal architectural distortion on mammography. All patients underwent contrast-enhanced breast MRI with a T1 Philips Gyroscan scanner and the acquisition of T1-weighted fast field echo, echo planar imaging (FFE EPI) axial dynamic sequences with a slice thickness of 3 mm. During postprocessing, subtracted images were assessed for morphological features, pattern of contrast enhancement, time-intensity curve and lesion enhancement rate.
  
  
  RESULTS
  Breast MRI depicted 27 lesions between 7 mm and 30 mm in size. Fifteen of the 27 breast lesions showed benign features, eight showed malignant features and four were classified as suspicious. Pathological examination confirmed the benignity of all 15 lesions showing benign MRI features and revealed the benign nature of the four lesions classified as suspicious.
  
  
  CONCLUSIONS
  Evaluation of breast MRI showed that enhancement rate and time-intensity curve were useful only in the differential diagnosis between benign and malignant breast lesions. Our experience confirmed that breast MRI has very high sensitivity and, in particular, a negative predictive value of 100%. Breast MRI could thus be considered a useful diagnostic tool that can guide the choice between follow-up or surgical excision of radial scars.
authors.affiliation: Azienda Ospedaliero-Universitaria OO.RR., Ospedali Riuniti, Foggia, Italy. drfperfetto@libero.it
authors.forename: F
authors.initials: F
authors.lastname: Perfetto
authors.forename: F
authors.initials: F
authors.lastname: Fiorentino
authors.forename: F
authors.initials: F
authors.lastname: Urbano
authors.forename: R
authors.initials: R
authors.lastname: Silecchia
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D002921:Cicatrix / Q000473:pathology*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008327:Mammography; D013382:Subtraction Technique
chemical_list: D003287:Contrast Media