title: First report of an Orientia tsutsugamushi type TA716-related scrub typhus infection in Thailand.
abstract: Orientia tsutsugamushi causes scrub typhus and is a rural zoonosis endemic in the Asia Pacific region. This is the first report of O. tsutsugamushi TA716-like strain in a human in Thailand. The patient was in the 1st trimester of pregnancy when she developed scrub typhus. The O. tsutsugamushi strain TA716 was detected from her admission blood sample, and the pregnancy ended in spontaneous abortion. The effects of scrub typhus in pregnant women and the pregnancy outcome are sparsely documented in the published medical literature. Improved clinical recognition and laboratory diagnosis will be essential to better define the morbidity caused by this zoonosis especially in pregnancy.
authors.affiliation: Shoklo Malaria Research Unit, Tak, Thailand.
authors.forename: Rose
authors.initials: R
authors.lastname: McGready
authors.forename: Stuart D
authors.initials: SD
authors.lastname: Blacksell
authors.forename: Rungnapa
authors.initials: R
authors.lastname: Luksameetanasan
authors.forename: Vanaporn
authors.initials: V
authors.lastname: Wuthiekanun
authors.forename: Wilairat
authors.initials: W
authors.lastname: Jedsadapanpong
authors.forename: Nicholas P J
authors.initials: NP
authors.lastname: Day
authors.forename: Francois
authors.initials: F
authors.lastname: Nosten
mesh_terms: D000328:Adult; D000818:Animals; D017963:Azithromycin / Q000627:therapeutic use; D002522:Chlorocebus aethiops; D005260:Female; D006801:Humans; D012285:Orientia tsutsugamushi / Q000145:classification*; D011247:Pregnancy; D012612:Scrub Typhus / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D014709:Vero Cells
chemical_list: D017963:Azithromycin