Double helix formation of poly(m-phenylene)s bearing achiral oligo(ethylene oxide) pendants and transformation into an excess of one-handed single helix through cholate binding in water.
A water-soluble poly(m-phenylene) bearing an achiral oligo(ethylene oxide) chain at the 5-position was synthesized by the Ni(0)-mediated homo-coupling polycondensation of a 3,5-dibromophenol monomer. The poly(m-phenylene) adopted a single helical conformation in protic media and self-assembled into a double helix in water through aromatic interaction, while it took a random-coil conformation in chloroform. Upon the addition of sodium cholate in water, the double helical poly(m-phenylene) was transformed into single strands, which bound the cholate molecules to form an excess of one-handed single helix.
Ben
Teng
T
Yashima Super-structured Helix Project, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Japan.
Furusho
Yoshio
Y
Goto
Hidetoshi
H
Miwa
Kazuhiro
K
Yashima
Eiji
E
D002942:Circular Dichroism; D005027:Ethylene Oxide / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D011108:Polymers / Q000737:chemistry*; D020358:Sodium Cholate / Q000737:chemistry*; D012995:Solubility; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D008055:Lipids; D011108:Polymers; D014867:Water; C041325:polyphenylene sulfide; D005027:Ethylene Oxide; D020358:Sodium Cholate