title: Simple cyclohexanediamine-derived primary amine thiourea catalyzed highly enantioselective conjugate addition of nitroalkanes to enones.
abstract: A highly enantioselective conjugate addition of nitroalkanes to enones has been developed. The process is efficiently catalyzed by a simple chiral cyclohexanediamine-derived primary amine thiourea with a broad substrate scope.
authors.affiliation: Department of Pharmaceutical Science, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
authors.forename: Kui
authors.initials: K
authors.lastname: Mei
authors.forename: Mei
authors.initials: M
authors.lastname: Jin
authors.forename: Shilei
authors.initials: S
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Wenjing
authors.initials: W
authors.lastname: Liu
authors.forename: Xiaobei
authors.initials: X
authors.lastname: Chen
authors.forename: Fei
authors.initials: F
authors.lastname: Xue
authors.forename: Wenhu
authors.initials: W
authors.lastname: Duan
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
mesh_terms: D000473:Alkanes / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003514:Cyclohexylamines / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
chemical_list: D000473:Alkanes; D000588:Amines; D003514:Cyclohexylamines; D007659:Ketones; D009574:Nitro Compounds; C030435:1,2-cyclohexanediamine; D013890:Thiourea