A flexible, convergent approach to polycyclic indole structures: formal synthesis of (+/-)-mersicarpine.
The formal synthesis of (+/-)-mersicarpine was achieved using an intermolecular radical addition-radical cyclization cascade. This key reaction represents a flexible, convergent route to numerous polycyclic indole derivatives.
Biechy
Aurélien
A
Laboratoire de Synthèse Organique, CNRS UMR 7652, Département de Chimie, Ecole Polytechnique, 91128 Palaiseau, France.
Zard
Samir Z
SZ
D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D026121:Indole Alkaloids; D007211:Indoles; C529544:mersicarpine