Influence of omentoplasty on colonic anastomosis in animals submitted to hemorrhagic shock in rats.
OBJECTIVE
To analyze influence of omentoplasty on anastomosis in descending colon of rats. Rats were submitted to the hypovolemic shock of the hemorrhagic type by the Biomechanical Test of Pressure of Rupture by Liquid Distension (BTPRLD). In addition, establish a type of acute anemia in rats that are provided to the study.


METHODS
Comparative study between two groups of animals with ten rats in each one, all submitted to hemorrhagic shock for 30% volemic removal by the carotid artery. An anastomosis was performed in left colon. An anastomosis was performed in the left colon. Group 1 took place anastomosis with Polyvinyl Chloride (P.V.C) film to prevent the adhesions formation on sature line. Group 2 placed the great omentum around the anastomosis. Euthanasia occurred on the fifth day, when the anastomoses were submitted to the biomechanical test of pressure of rupture by liquid distension (BTPRLD).


RESULTS
High rupture pressure was gained with omentoplasty group in relation to the group in which anastomosis was protected from adhesions formation. A statistical significance was noted.


CONCLUSIONS
Protection by great omentum has increased the anastomosis resistance of the shocked animals. Also, the proposed hemorrhagic shock type has proven to be useful for this study.
Bolzam-Nascimento
Ricardo
R
Department of Surgery, UNICAMP, Sao Paulo, Brazil. ricardobolzam@yahoo.com.br
Coy
Cláudio Saddy Rodrigues
CS
Pereira
Yara Ematné Amaral
YE
Leal
Raquel Franco
RF
Reis
Rosana Celestina Morandin
RC
Mantovani
Mário
M
Ayrizono
Maria de Lourdes Setsuko
Mde L
Chung
Wu Feng
WF
Fagundes
João José
JJ
D000704:Analysis of Variance; D000714:Anastomosis, Surgical; D000818:Animals; D003106:Colon / Q000601:surgery*; D003108:Colonic Diseases / Q000601:surgery*; D004195:Disease Models, Animal; D008297:Male; D009852:Omentum / Q000601:surgery*; D051381:Rats; D017208:Rats, Wistar; D012771:Shock, Hemorrhagic / Q000150:complications*; D018709:Statistics, Nonparametric; D014945:Wound Healing / Q000502:physiology*