Copper(I)-catalyzed aryl bromides to form intermolecular and intramolecular carbon-oxygen bonds.
A highly efficient Cu-catalyzed C-O bond-forming reaction of alcohol and aryl bromides has been developed. This transformation was realized through the use of copper(I) iodide as a catalyst, 8-hydroxyquinoline as a ligand, and K(3)PO(4) as a base. A variety of functionalized substrates were found to react under these reaction conditions to provide products in good to excellent yields.
Niu
Jiajia
J
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People's Republic of China.
Guo
Pengran
P
Kang
Juntao
J
Li
Zhigang
Z
Xu
Jingwei
J
Hu
Shaojing
S
D001965:Bromides / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D010100:Oxygen / Q000737:chemistry*; D015125:Oxyquinoline / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry; D017680:Potassium Compounds / Q000737:chemistry
D001965:Bromides; D008024:Ligands; D010710:Phosphates; D017680:Potassium Compounds; D015125:Oxyquinoline; D002244:Carbon; D003300:Copper; C013216:potassium phosphate; D010100:Oxygen