title: In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve.
abstract: An ultra-high-speed spectral-domain optical coherence tomography system (SD-OCT) was developed for imaging the human retina and optic nerve in vivo at a sustained depth profile (A-line) acquisition speed of 29 kHz. The axial resolution was 6 microm in tissue and the system had shot-noise-limited performance with a maximum sensitivity of 98.4 dB. 3-dimensional data sets were collected in 11 and 13 seconds for the macula and optic nerve head respectively and are presented to demonstrate the potential clinical applications of SD-OCT in ophthalmology. Additionally, a 3-D volume of the optic nerve head was constructed from the acquired data and the retinal vascular network was visualized.
authors.forename: N
authors.initials: N
authors.lastname: Nassif
authors.forename: B
authors.initials: B
authors.lastname: Cense
authors.forename: B
authors.initials: B
authors.lastname: Park
authors.forename: M
authors.initials: M
authors.lastname: Pierce
authors.forename: S
authors.initials: S
authors.lastname: Yun
authors.forename: B
authors.initials: B
authors.lastname: Bouma
authors.forename: G
authors.initials: G
authors.lastname: Tearney
authors.forename: T
authors.initials: T
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: de Boer