title: First trimester neurosonoembryology with automated follicle tracking: preliminary findings.
abstract: We evaluated the feasibility of demonstration of the embryonic cerebral ventricles using three dimensional transvaginal ultrasonography and software which has been developed to automatically calculate the volume of ovarian follicles after ovarian stimulation. In four out of six subsequent ultrasound examinations which were done for determination of gestational age from eight to ten gestational weeks, sufficient resolution was obtained to demonstrate the embryonic cerebral ventricles with automated volume calculation software, yielding striking images of a dramatic stage of embryonic development.
authors.affiliation: Division of Perinatology and Gynaecology, Department of Obstetrics, Wilhelmina Childrens' Hospital KE 04.123.1, University Medical Centre, PO Box 85090, Utrecht 3508 AB, The Netherlands. l.pistorius@umcutrecht.nl
authors.forename: Lourens
authors.initials: L
authors.lastname: Pistorius
authors.forename: Philip
authors.initials: P
authors.lastname: Stoutenbeek
authors.forename: Gerard H A
authors.initials: GH
authors.lastname: Visser
mesh_terms: D000465:Algorithms; D048429:Cell Size; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging* / Q000196:embryology*; D047108:Embryonic Development / Q000502:physiology; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D006080:Ovarian Follicle / Q000166:cytology*; D010865:Pilot Projects; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011272:Pregnancy, Multiple / Q000502:physiology; D014310:Triplets; D016216:Ultrasonography, Prenatal / Q000379:methods