title: Postirradiation osteosarcoma of the maxilla: a case report and current review of literature.
abstract: Background. Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy. They are of rare occurrence in jaw bones and are even rarer in the maxilla. Case report. We report a case of radiation-induced osteosarcoma involving the maxilla in a patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago. Despite neoadjuvant chemotherapy, surgical treatment could not be performed, and the patient received palliative chemotherapy. Conclusions. Radiation-induced osteosarcomas are aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention.
authors.affiliation: Department of Medical Oncology, University Hospital Farhat Hached, Sousse 4000, Tunisia.
authors.forename: Imene
authors.initials: I
authors.lastname: Chabchoub
authors.forename: Olfa
authors.initials: O
authors.lastname: Gharbi
authors.forename: Sami
authors.initials: S
authors.lastname: Remadi
authors.forename: Sami
authors.initials: S
authors.lastname: Limem
authors.forename: Amel
authors.initials: A
authors.lastname: Trabelsi
authors.forename: Makrem
authors.initials: M
authors.lastname: Hochlef
authors.forename: Leila
authors.initials: L
authors.lastname: Ben Fatma
authors.forename: Amel
authors.initials: A
authors.lastname: Landolsi
authors.forename: Moncef
authors.initials: M
authors.lastname: Mokni
authors.forename: Chekib
authors.initials: C
authors.lastname: Kraiem
authors.forename: Slim
authors.initials: S
authors.lastname: Ben Ahmed