A unified strategy for the stereospecific construction of propionates and acetate-propionates relying on a directed allylic substitution.
Flexible friends: A new strategy that relies on o-DPPB-directed allylic substitution has been implemented for the flexible and stereospecific construction of major polyketide and isoprenoid structural elements (see scheme; o-DPPB=ortho-diphenylphosphanyl benzoate; PG=protecting group).
Reiss
Tomislav
T
Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg i. Brsg. Albertstrasse 21, 79104 Freiburg i. Brsg., Germany.
Breit
Bernhard
B