Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide.
A 39-year-old white woman with longstanding Crohn's disease presented with the rare complication of granulomatous bronchiolitis. Rapid resolution after inhaled budesonide is highlighted, as this is the first case described in the literature successfully treated without the need for systemic therapy. This less toxic approach to therapy is warranted in granulomatous bronchiolitis of Crohn's disease to avoid unwanted side effects of steroids and infliximab.
Trow
T K
TK
Yale University School of Medicine, New Haven, Connecticut 06520-8057, USA. terence.trow@yale.edu
Morris
D G
DG
Miller
C R
CR
Homer
R J
RJ
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001988:Bronchiolitis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D019819:Budesonide / Q000627:therapeutic use*; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D015769:Granuloma, Respiratory Tract / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D019819:Budesonide