title: Correlated movement and bending of nucleic acid structures visualized by multicolor single-molecule spectroscopy.
abstract: At the end of the rainbow.... The structure and dynamics of three- and four- way DNA junctions are studied using triple alternating laser excitation. Steroid binding distorts the structure of three-way junctions with correlated bending of all branches towards a steeper pyramid (see picture). In four-way junctions, the dynamics of three distances are visualized simultaneously.
authors.affiliation: Applied Physics-Biophysics, and Center for NanoScience, Ludwig-Maximilians Universität, München, Germany.
authors.forename: Britta
authors.initials: B
authors.lastname: Person
authors.forename: Ingo H
authors.initials: IH
authors.lastname: Stein
authors.forename: Christian
authors.initials: C
authors.lastname: Steinhauer
authors.forename: Jan
authors.initials: J
authors.lastname: Vogelsang
authors.forename: Philip
authors.initials: P
authors.lastname: Tinnefeld
mesh_terms: D004247:DNA / Q000737:chemistry*; D045566:DNA, Cruciform / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D007834:Lasers; D009690:Nucleic Acid Conformation; D013050:Spectrometry, Fluorescence; D013256:Steroids / Q000737:chemistry
chemical_list: D045566:DNA, Cruciform; D013256:Steroids; D004247:DNA