title: Usefulness of C-reactive protein, serum amyloid A component, and haptoglobin determinations in bitches with pyometra for monitoring early post-ovariohysterectomy complications.
abstract: The aim of this study was to assess changes in serum concentrations of C-reactive protein (CRP), serum amyloid A component (SAA), and haptoglobin (Hp) in bitches with pyometra undergoing ovariohysterectomy that developed postoperative wound infection-related complications. The study revealed that difficulties in postoperative wound healing were induced by infections with Escherichia coli and Staphylococcus spp. leading to re-increased levels of CRP and SAA immediately after surgery and persistently high Hp levels throughout the experiment. Our results indicate that acute-phase proteins in bitches undergoing surgery because of pyometra are useful markers for monitoring the postoperative period. Moreover, they enable prompt therapeutic management once complications develop.
authors.affiliation: Department and Clinic of Animal Reproduction, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 30, Głeboka St., 20-612 Lublin, Poland. roman.dabrowski@up.lublin.pl
authors.forename: R
authors.initials: R
authors.lastname: Dabrowski
authors.forename: K
authors.initials: K
authors.lastname: Kostro
authors.forename: U
authors.initials: U
authors.lastname: Lisiecka
authors.forename: M
authors.initials: M
authors.lastname: Szczubiał
authors.forename: L
authors.initials: L
authors.lastname: Krakowski
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism*; D004283:Dog Diseases / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*; D004285:Dogs; D004927:Escherichia coli Infections / Q000150:complications / Q000175:diagnosis / Q000662:veterinary; D005260:Female; D006242:Haptoglobins / Q000378:metabolism*; D007044:Hysterectomy / Q000662:veterinary; D010052:Ovariectomy / Q000662:veterinary; D011182:Postoperative Care / Q000662:veterinary; D055112:Pyometra / Q000601:surgery / Q000662:veterinary*; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D013203:Staphylococcal Infections / Q000150:complications / Q000175:diagnosis / Q000662:veterinary; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*
chemical_list: D015415:Biomarkers; D006242:Haptoglobins; D000685:Serum Amyloid A Protein; D002097:C-Reactive Protein