Gold nanoparticles prepared using cape aloe active components.
A novel use of two components of Cape aloe, aloin A and aloesin, acting as stabilizers in the preparation of gold and silver nanoparticles, is reported. Stable water-soluble particles of different size and shape are prepared by varying the reaction conditions, temperature, reaction time, and reducing agents. Characterization of the obtained particles is performed using UV-visible, attenuated total reflection Fourier transform infrared (ATR-FTIR), and 1H NMR spectroscopies and transmission electron microscopy (TEM). The efficient cellular uptake of 50 nm sized aloin A and aloesin stabilized gold particles into macrophages and HeLa cells was investigated, proposing these particles as nanovehicles.
Krpetić
Zeljka
Z
Dipartimento di Chimica Inorganica Metallorganica Analitica Lamberto Malatesta, University of Milan, Via Venezian 21, Milan, Italy.
Scarì
Giorgio
G
Caneva
Enrico
E
Speranza
Giovanna
G
Porta
Francesca
F
D002867:Chromones / Q000737:chemistry* / Q000494:pharmacology; D004642:Emodin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D022161:Transport Vesicles / Q000737:chemistry*
D002867:Chromones; D005960:Glucosides; D010936:Plant Extracts; D006046:Gold; D004642:Emodin; C006457:alloin; C069868:aloesin