Viral vectors for stable transduction of human mesenchymal stem cells: systems based on adeno-associated viruses and lentiviruses.
We compared the efficiency of transduction with lentivectors based on HIV-1 and adeno-associated viruses serotype 2 and stability of transgene expression in human mesenchymal bone marrow stem cells.
Shakhbazau
A V
AV
Institute of Genetics and Cytology, National Academy of Sciences of Belarus, Minsk, Belarussia. shakhbazau@gmail.com
Sevyaryn
I N
IN
Goncharova
N V
NV
Grinev
V V
VV
Kosmacheva
S M
SM
Potapnev
M P
MP
D002460:Cell Line; D000229:Dependovirus / Q000235:genetics*; D005822:Genetic Vectors / Q000235:genetics*; D006801:Humans; D016086:Lentivirus / Q000235:genetics*; D059630:Mesenchymal Stem Cells / Q000821:virology*; D014162:Transfection / Q000379:methods*