Storage of cryopreserved reproductive tissues: evidence that cross-contamination of infectious agents is a negligible risk.
A misconception in the field of reproductive medicine is that there is a significant risk of cross-contamination during gamete or embryo cryostorage. This article is a review of the available literature on animal models and human IVF and it suggests otherwise. There is a negligible risk of cross-contamination in IVF working conditions.
Pomeroy
Kimball O
KO
Arizona Reproductive Medicine Specialists, Phoenix, Arizona.
Harris
Stanley
S
Methodist Hospital, Omaha, Nebraska.
Conaghan
Joe
J
Pacific Fertility Center, San Francisco, California.
Papadakis
Margaret
M
Carolinas Medical Center, Charlotte, North Carolina.
Centola
Grace
G
Macedon, New York.
Basuray
Rita
R
University of Kentucky, Lexington, Kentucky.
Battaglia
David
D
Oregon Health and Science University, Portland, Oregon. Electronic address: battagli@ohsu.edu.
D003141:Communicable Diseases / Q000453:epidemiology / Q000209:etiology; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology*; D015925:Cryopreservation / Q000379:methods*; D004622:Embryo, Mammalian; D006801:Humans; D012098:Reproduction / Q000502:physiology; D027724:Reproductive Techniques, Assisted / Q000331:legislation & jurisprudence / Q000592:standards; D012307:Risk Factors; D012661:Semen; D013048:Specimen Handling / Q000379:methods / Q000592:standards; D014021:Tissue Preservation / Q000379:methods* / Q000592:standards; D014481:United States; D014486:United States Food and Drug Administration / Q000331:legislation & jurisprudence