title: IBiox[(-)-menthyl]: a sterically demanding chiral NHC ligand.
abstract: An exceedingly sterically demanding, rigid, and chiral NHC ligand, IBiox[(-)-menthyl] (1), was prepared and structurally characterized. With a buried volume of approximately 50%, this ligand arguably represents one of the most sterically demanding monodentate ligands. The ability to use aryl chloride substrates in intramolecular palladium-catalyzed alpha-arylations reveals its unique reactivity. Moreover, C(2)-symmetric 1 allows the highly enantioselective formation of oxindoles with up to 99% ee.
authors.affiliation: Organisch-Chemisches Institut der Westfälischen Wilhelms-Universität Munster, Corrensstrasse 40, 48149 Münster, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Würtz
authors.forename: Claudia
authors.initials: C
authors.lastname: Lohre
authors.forename: Roland
authors.initials: R
authors.lastname: Fröhlich
authors.forename: Klaus
authors.initials: K
authors.lastname: Bergander
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius