The second wind phenomenon in very young McArdle's patients.
We investigated the phenomenon of second wind in four patients with McArdle's disease: a brother and sister (aged 4 and 12 years respectively) and two unrelated patients, a boy of 14 and a 17-year-old girl. We also studied the siblings' healthy 6-year-old sister. Each patient performed a 15-min exercise test at a constant workload and a subsequent graded exercise test until exhaustion. Overall the healthy girl and the youngest McArdle's patient, the 4-year-old boy, did not show a second wind phenomenon. Further, the peak cardio-respiratory capacity of the young McArdle's boy was normal for his age (32.3 mL 02/kg/min) and he did not report any function limitations during physical education classes.
Pérez
Margarita
M
Universidad Europea de Madrid (Polideportivo), 28670 Villaviciosa de Odón, Madrid, Spain.
Ruiz
Jonatan R
JR
Fernández Del Valle
María
M
Nogales-Gadea
Gisela
G
Andreu
Antoni L
AL
Arenas
Joaquín
J
Lucía
Alejandro
A
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006012:Glycogen Storage Disease Type V / Q000175:diagnosis / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D008297:Male; D012123:Pulmonary Ventilation