Persistent pupillary dilation in herpes simplex uveitis.
OBJECTIVE
To report the association between herpes simplex virus (HSV) and iris atrophy with pupillary dilation.


METHODS
Retrospective case series.


METHODS
Patients with a clinical diagnosis of HSV keratouveitis seen between November 1993 and April 1994 in a single university uveitis clinic. There were 6 women and 7 men, aged 17 to 69 years (mean age 44.4 years).


METHODS
Patient information was collected, including history and medications used, and a complete ophthalmologic evaluation was performed, with careful documentation of iris detail and pupillary size.


RESULTS
Thirteen of 13 patients demonstrated some degree of iris atrophy; 9 of 13 had pupillary dilation on the affected side despite not being on dilating drops.


CONCLUSIONS
Iris atrophy and pupillary dilation in a patient with unexplained anterior uveitis suggests the diagnosis of HSV keratouveitis.
Goldstein
Debra A
DA
University of Illinois at Chicago Eye and Ear Infirmary, 60612-7243, USA. debrgold@uic.edu
Mis
Andrew A
AA
Oh
Frederick S
FS
Deschenes
Jean G
JG
D000293:Adolescent; D000328:Adult; D000368:Aged; D001284:Atrophy; D015828:Eye Infections, Viral / Q000473:pathology / Q000821:virology*; D005260:Female; D005500:Follow-Up Studies; D006561:Herpes Simplex / Q000473:pathology / Q000821:virology*; D006801:Humans; D007498:Iris / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011681:Pupil Disorders / Q000473:pathology / Q000821:virology*; D012189:Retrospective Studies; D014606:Uveitis, Anterior / Q000473:pathology / Q000821:virology*; D055815:Young Adult