title: Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes.
abstract: Synthesis of novel quinoline based dicationic benzimidazolophanes and imidazolophanes incorporating various spacer units is described. Some of the quinolinophanes 1b, 3a,3b and 4a exhibit good antibacterial activity against most of the human pathogenic bacteria in the tested concentrations as compared to the other cyclophanes as well as the test control, streptomycin.
authors.affiliation: Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, India. perumalrajakumar@hotmail.com
authors.forename: Perumal
authors.initials: P
authors.lastname: Rajakumar
authors.forename: Rathinam
authors.initials: R
authors.lastname: Raja
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Selvam
authors.forename: Ramasamy
authors.initials: R
authors.lastname: Rengasamy
authors.forename: Subramani
authors.initials: S
authors.lastname: Nagaraj
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D007093:Imidazoles; D011804:Quinolines