title: Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum.
abstract: Mutiniside (1), new phenolic glucoside, and the flavonoidal glucoside cephacoside (2) have been isolated from the n-BuOH soluble fraction, along with lupeol (3), beta-sitosterol (4), stigmasterol (5), methyl-4-hydroxybenzoate (6), taraxacin (7), ursolic acid (8), and beta-sitosterol-3-O-beta-D-glucopyranoside (9), have been isolated from the EtOAc soluble fraction of Abutilon muticum. Compounds 2-9 are reported for the first time from this species. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase.
authors.affiliation: Pharmaceutical Research Centre, PCSIR Laboratories Complex Karachi, Karachi, Pakistan.
authors.forename: Samar
authors.initials: S
authors.lastname: Ali
authors.forename: Shazia
authors.initials: S
authors.lastname: Yasmeen
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Lubna
authors.initials: L
authors.lastname: Iqbal
authors.forename: Mehreen
authors.initials: M
authors.lastname: Lateef
authors.forename: Naheed
authors.initials: N
authors.lastname: Riaz
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ashraf
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019660:Malvaceae / Q000737:chemistry*; D015394:Molecular Structure; D010154:Pakistan; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D016859:Lipoxygenase Inhibitors; D010636:Phenols; D010851:Picrates; D012855:Sitosterols; C541316:mutiniside; C472604:sitosterol-3-O-glucopyranoside; C025473:gamma-sitosterol; C004931:1,1-diphenyl-2-picrylhydrazyl