New benzophenone O-glucoside from Hypericum ellipticum.
Examination of the acetone extract of the aerial parts of Hypericum ellipticum afforded a new acetylated benzophenone glucoside (3'-O-beta-D-3",4",6"-triacetylglucopyranosyl-2,4,5',6-tetrahydroxybenzophenone) together with catechin and epicatechin. The structure of the benzophenone glucoside was determined by 2D NMR spectroscopic data. The compound inhibited the proliferation of CNS tumor cell line (SF-268) and lipid peroxidation in in vitro assays.
Petrunak
Elyse
E
Department of Chemistry, Susquehanna University, 514 University Avenue, Selinsgrove, PA 17870, USA.
Kester
Andrew C
AC
Liu
Yunbao
Y
Bowen-Forbes
Camile S
CS
Nair
Muraleedharan G
MG
Henry
Geneive E
GE
D001577:Benzophenones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D054697:Cytostatic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D020902:Hypericum / Q000737:chemistry*; D015227:Lipid Peroxidation / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular
C542120:3'-O-3'',4'',6''-triacetylglucopyranosyl-2,4,5',6-tetrahydroxybenzophenone; D001577:Benzophenones; D054697:Cytostatic Agents; D005960:Glucosides; D002392:Catechin