title: At loose ends: resecting a double-strand break.
abstract: Double-strand break (DSB) repair is critical for maintaining genomic integrity and requires the processing of the 5' DSB ends. Recent studies have shed light on the mechanism and regulation of DNA end processing during DSB repair by homologous recombination.
authors.affiliation: Columbia University Medical Center, Department of Genetics & Development, New York, NY 10032, USA.
authors.forename: Kara A
authors.initials: KA
authors.lastname: Bernstein
authors.forename: Rodney
authors.initials: R
authors.lastname: Rothstein
mesh_terms: D000818:Animals; D001105:Archaea / Q000378:metabolism; D002453:Cell Cycle; D053903:DNA Breaks, Double-Stranded; D004260:DNA Repair; D006801:Humans