title: Attitude towards adherence in patients with schizophrenia at discharge.
abstract: BACKGROUND
  Purpose of the present study was to assess the attitude towards adherence at discharge and to verify its predictability using anamnestic and sociodemographic variables, factors influencing clinical treatment as well as the medical treatment applied.
  
  
  METHODS
  Attitude towards adherence was evaluated in 369 inpatients with schizophrenic spectrum disorders within a naturalistic multicenter trial using the Compliance Rating Scale (CRS) by Kemp. Biweekly ratings of the PANSS, UKU and the Subjective Well-being under Neuroleptic Treatment Scale (SWN-K) were applied. Logistic regression and CART analyses were used to determine significant predictor variables for the attitude towards adherence at discharge.
  
  
  RESULTS
  Sixty-seven percent of the patients were rated to have an attitude of active participation and moderate participation (=positive attitude towards adherence) and 33% of the patients to have an attitude of passive acceptance, occasional or permanent reluctance towards treatment as well as refusing treatment (=negative attitude towards adherence). A significant correlation was found between patients with a positive attitude towards adherence and course of all PANSS subscales. Statistical analyses revealed a reduction in PANSS general psychopathology subscore, employment status, greater illness insight and treatment with atypical antipsychotics to be significantly predictive for a positive attitude towards adherence at discharge.
  
  
  CONCLUSIONS
  The importance of an adequate antipsychotic treatment as a precondition for a favourable adherence attitude and the need to incorporate adherence-focused psychotherapy and psychoeducation into daily clinical practice are highlighted.
authors.affiliation: Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstr. 7, 80336 Munich, Germany. Rebecca.Schennach-Wolff@med.uni-muenchen.de
authors.forename: Rebecca
authors.initials: R
authors.lastname: Schennach-Wolff
authors.forename: Markus
authors.initials: M
authors.lastname: Jäger
authors.forename: Florian
authors.initials: F
authors.lastname: Seemüller
authors.forename: Michael
authors.initials: M
authors.lastname: Obermeier
authors.forename: Thomas
authors.initials: T
authors.lastname: Messer
authors.forename: Gerd
authors.initials: G
authors.lastname: Laux
authors.forename: Herbert
authors.initials: H
authors.lastname: Pfeiffer
authors.forename: Dieter
authors.initials: D
authors.lastname: Naber
authors.forename: Lutz G
authors.initials: LG
authors.lastname: Schmidt
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Gaebel
authors.forename: Joachim
authors.initials: J
authors.lastname: Klosterkötter
authors.forename: Isabella
authors.initials: I
authors.lastname: Heuser
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Maier
authors.forename: Matthias R
authors.initials: MR
authors.lastname: Lemke
authors.forename: Eckart
authors.initials: E
authors.lastname: Rüther
authors.forename: Stefan
authors.initials: S
authors.lastname: Klingberg
authors.forename: Markus
authors.initials: M
authors.lastname: Gastpar
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Möller
authors.forename: Michael
authors.initials: M
authors.lastname: Riedel
mesh_terms: D000328:Adult; D001294:Attitude to Health; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011569:Psychiatric Status Rating Scales; D012189:Retrospective Studies; D012559:Schizophrenia; D012565:Schizophrenic Psychology; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D013997:Time Factors; D016903:Drug Monitoring