title: Total blood mercury concentrations in the U.S. population: 1999-2006.
abstract: We describe the distribution and demographic characteristics of total blood Hg levels in the U.S. general population among persons ages 1 year and older who participated in the 2003-2006 National Health and Nutrition Examination Survey (NHANES). We also describe trends in the total blood Hg of children ages 1-5 (n=3456) and females ages 16-49 during 1999-2006 (n=7245). In the combined 2003-2006 survey periods, the geometric means for non-Hispanic blacks, 0.853microg/L (95% confidence interval [CI], 0.766-0.950microg/L), and non-Hispanic whites, 0.833microg/L (95% CI, 0.752-0.922microg/L), were higher than the geometric mean for Mexican Americans, 0.580microg/L (95% CI, 0.522-0.645microg/L). Also in 2003-2006, regression analysis of log total blood Hg with age, race/ethnicity and gender showed that total blood Hg levels in the population exhibited a quadratic increase with age (p<0.0001), peaking at ages 50-59 in non-Hispanic blacks and whites, at ages 40-49 in Mexican Americans, and then declining at older ages. Over the four survey periods (1999-2006), regression analysis showed that total blood Hg levels increased slightly for non-Hispanic white children and decreased slightly for non-Hispanic black and Mexican American children. Over the same four survey periods, female children had slightly higher total blood Hg levels than males (0.356 vs. 0.313microg/L, p=0.0050) and total blood Hg levels in non-Hispanic black women aged 16-49 years were significantly higher than in non-Hispanic white women (1.081 vs. 0.850microg/L, p<0.0001) and in Mexican American women (1.081 vs. 0.70microg/L, p<0.0001).
authors.affiliation: Division of Laboratory Sciences, National Center for Environmental Health, CDC, 4770 Buford Highway, NE, Mailstop F-18, Atlanta, GA 30341, USA. kcaldwell@cdc.gov
authors.forename: Kathleen L
authors.initials: KL
authors.lastname: Caldwell
authors.forename: Mary E
authors.initials: ME
authors.lastname: Mortensen
authors.forename: Robert L
authors.initials: RL
authors.lastname: Jones
authors.forename: Samuel P
authors.initials: SP
authors.lastname: Caudill
authors.forename: John D
authors.initials: JD
authors.lastname: Osterloh
mesh_terms: D000293:Adolescent; D000328:Adult; D001741:Black or African American; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D007223:Infant; D008297:Male; D008628:Mercury / Q000097:blood*; D008875:Middle Aged; D011159:Population Surveillance; D012044:Regression Analysis; D014481:United States; D044465:White People
chemical_list: D008628:Mercury