title: The effects of topical levobupivacaine on morbidity in pediatric tonsillectomy patients.
abstract: OBJECTIVE
  To reduce the post-tonsillectomy morbidity by swab soaked with 5 ml levobupivacaine hydroclorur (25 mg/10 ml).
  
  
  METHODS
  A double-blind prospective randomized controlled clinical study.
  
  
  METHODS
  In this randomized double-blind study in group I (30 children, mean age 7.5+/-2.6) we tightly packed swab soaked with 5 ml levobupivacaine hydroclorur (25mg/10 ml) and in group II (21 children, mean age 7.9+/-3.7) we used 5 ml saline swabs into each of the two tonsillar fossae after tonsillectomy for 5 min. We used McGrath's face scale to compare the two groups in respect of pain control.
  
  
  RESULTS
  There was statistically significant pain relieving effect in the levobupivacaine group in the first 24h (p<0.05). But after 24h pain relieving effect of levobupivacaine was not significant (p>0.05). We did not see any serious complications for both groups. Postoperative morbidity mean results (nausea, vomiting, fever, bleeding, halitosis and ear pain) were not statistically different between the two groups (p>0.05).
  
  
  CONCLUSIONS
  Topical levobupivacaine seems to be a safe and easy medication for postoperative pain control in pediatric tonsillectomy patients.
authors.affiliation: Duzce University, Duzce Medical Faculty, Department of ENT and Head & Neck Surgery, Duzce, Turkey. dryilmazsuleyman@yahoo.com
authors.forename: Süleyman
authors.initials: S
authors.lastname: Yilmaz
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Demiraran
authors.forename: Nermin
authors.initials: N
authors.lastname: Akkan
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Yaman
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Iskender
authors.forename: Ender
authors.initials: E
authors.lastname: Güçlü
authors.forename: Ozcan
authors.initials: O
authors.lastname: Oztürk
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage / Q000031:analogs & derivatives; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D000077554:Levobupivacaine; D008297:Male; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D020250:Postoperative Nausea and Vomiting / Q000209:etiology / Q000517:prevention & control; D014068:Tonsillectomy / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D000077554:Levobupivacaine; D002045:Bupivacaine