Let's play polo in the field of condensation.
In this issue of Molecular Cell, St-Pierre et al. (2009) present evidence that, in budding yeast, the polo kinase Cdc5 directly phosphorylates and activates condensin to promote anaphase-specific rDNA condensation.
Hirano
Tatsuya
T
RIKEN Advanced Science Institute, Chromosome Dynamics Laboratory, Wako, Saitama, Japan. hiranot@riken.jp
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000705:Anaphase / Q000502:physiology*; D016203:CDC2 Protein Kinase / Q000235:genetics / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D004275:DNA, Ribosomal / Q000235:genetics* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D046912:Multiprotein Complexes / Q000378:metabolism*; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases; D021122:Protein Subunits / Q000235:genetics / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*
D018797:Cell Cycle Proteins; D004275:DNA, Ribosomal; D004268:DNA-Binding Proteins; D046912:Multiprotein Complexes; D021122:Protein Subunits; D029701:Saccharomyces cerevisiae Proteins; C108312:condensin complexes; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; C081927:CDC5 protein, S cerevisiae; D016203:CDC2 Protein Kinase; D000251:Adenosine Triphosphatases