title: Three-dimensional coregistered optical coherence tomography and line-scanning fluorescence laminar optical tomography.
abstract: We present a combined optical coherence tomography (OCT) and line-scanning fluorescence laminar optical tomography (FLOT) system. This hybrid system enables coregistered structural and molecular imaging in 3D with 10-100 microm resolution and millimeter-scale imaging depth. Experimental results on a capillary phantom with fluorescence dye Cy5.5 using an OCT/FLOT imaging system have been demonstrated.
authors.affiliation: Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA.
authors.forename: Shuai
authors.initials: S
authors.lastname: Yuan
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.forename: James
authors.initials: J
authors.lastname: Jiang
authors.forename: Alex
authors.initials: A
authors.lastname: Cable
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
mesh_terms: D005453:Fluorescence; D021621:Imaging, Three-Dimensional / Q000379:methods*; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*