Catalytic synthesis of amino acid and peptide derivatized gadonanotubes.
A new Rh(6)(CO)(16)-catalyzed functionalization of gadonanotube MRI probes offers the opportunity to prepare a number of amino acid and peptide derivatized gadonanotubes under RT conditions, containing, for example, the cyclic RGD peptide for the biological targeting of cancer.
Mackeyev
Yuri
Y
Department of Chemistry, Smalley Institute for Nanoscale Science and Technology, and the Center for Biological and Environmental Nanotechnology, MS 60, P.O. Box 1892, Rice University, Houston, Texas 77251-1892, USA.
Hartman
Keith B
KB
Ananta
Jeyarama S
JS
Lee
Adrian V
AV
Wilson
Lon J
LJ
D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D005682:Gadolinium / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D045333:Nanotubes, Peptide / Q000737:chemistry*; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D009942:Organometallic Compounds; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry
D000596:Amino Acids; D001672:Biocompatible Materials; D045333:Nanotubes, Peptide; D009842:Oligopeptides; D009942:Organometallic Compounds; D010456:Peptides, Cyclic; C047981:arginyl-glycyl-aspartic acid; D005682:Gadolinium; D012238:Rhodium