title: [Chronic disseminated intravascular coagulopathy in a dog with lung worm infection].
abstract: The clinical and laboratory findings in a 1-year-old male Jack Russel Terrier dog with lung worm induced coagulopathy are described. The diagnosis was based upon history, clinical findings, radiography, endoscopy, cytology and laboratory results. The presenting complaint was chronic cough. Radiographically, a diffuse interstitial to bronchial lung pattern was observed. Blood analysis revealed thrombocytopaenia and prolonged coagulation times. Disseminated intravascular coagulopathy (DIC) was diagnosed based on D-dimer and fibrinogen measurements, and by thrombelastogram results. After stabilisation of the patient, bronchoscopy with a bronchoalveolar lavage was performed, where large amounts of lung worm larvae were found cytologically. After treatment with fresh frozen plasma and fenbendazole, coagulation parameters improved and the cough resolved.
authors.affiliation: Klinikum Veterinärmedizin, Klinik für Kleintiere der Justus-Liebig-Universität Giessen.
authors.forename: S
authors.initials: S
authors.lastname: Schmitz
authors.forename: A
authors.initials: A
authors.lastname: Moritz
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D001777:Blood Coagulation; D018893:Bronchoalveolar Lavage / Q000662:veterinary*; D001992:Bronchoalveolar Lavage Fluid / Q000469:parasitology; D001999:Bronchoscopy / Q000662:veterinary; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D005338:Fibrin Fibrinogen Degradation Products; D008174:Lung Diseases, Parasitic / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D009349:Nematode Infections / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D000969:Antinematodal Agents; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D