title: Comorbidities of obesity.
abstract: Obesity, especially visceral adiposity, is associated with morbidity and mortality through endocrine and mechanical processes. Clinical manifestations due to effects of obesity on the cardiovascular, respiratory, gastrointestinal, musculoskeletal, immune, and integumentary systems have been described. Further studies are needed to understand the pathologic processes underlying these clinical manifestations to improve disease prevention.
authors.affiliation: Department of Family Medicine, University of Pittsburgh School of Medicine, 3518 Fifth Avenue, Pittsburgh, PA 15261, USA.
authors.forename: Kavitha Bhat
authors.initials: KB
authors.lastname: Schelbert
mesh_terms: D017667:Adipocytes / Q000378:metabolism; D052242:Adiponectin / Q000378:metabolism; D050154:Adiposity / Q000502:physiology; D002318:Cardiovascular Diseases / Q000150:complications / Q000503:physiopathology; D004734:Energy Metabolism; D015444:Exercise; D005767:Gastrointestinal Diseases / Q000150:complications / Q000503:physiopathology; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D050152:Intra-Abdominal Fat / Q000503:physiopathology; D020738:Leptin / Q000378:metabolism; D009140:Musculoskeletal Diseases / Q000150:complications / Q000503:physiopathology; D009369:Neoplasms / Q000150:complications / Q000503:physiopathology; D009765:Obesity / Q000150:complications* / Q000503:physiopathology; D012140:Respiratory Tract Diseases / Q000150:complications / Q000503:physiopathology
chemical_list: D052242:Adiponectin; D020738:Leptin