title: Developments in the scientific understanding of osteoporosis.
abstract: During the past 10 years we have experienced very significant developments in our understanding of bone biology, and this has improved our abilities to both diagnose and treat patients with osteoporosis. This review covers some of the significant discoveries in bone biology that have led to a better understanding of osteoporosis, including a few of the discoveries that have been translated into new therapies to treat patients with osteoporosis and the structural deterioration of patients with inflammatory arthritis.
authors.affiliation: Department of Medicine, Aging Center, Medicine and Rheumatology, University of California at Davis Medical School, Sacramento, CA 95817, USA. nelane@ucdavis.edu
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Lane
authors.forename: Wei
authors.initials: W
authors.lastname: Yao
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000379:methods / Q000639:trends*; D006801:Humans; D010024:Osteoporosis / Q000378:metabolism / Q000473:pathology* / Q000628:therapy*; D015398:Signal Transduction / Q000502:physiology