title: Novel chiral derivatizing isothiocyanate-based agent for the enantiomeric excess determination of amines.
abstract: The expedient synthesis of a novel chiral (1S,2S)-N-[(2-isothiocyanato)cyclohexyl] trifluoromethanesulfonamide and its use as a derivatizing auxiliary for the straightforward determination of optical purity of chiral amines are reported.
authors.affiliation: Laboratoire des Systèmes Chimiques Fonctionnels, UMR 7199-CNRS, Université de Strasbourg, 74 Route du RhinB.P 60024, 67401 Illkirch Graffenstaden cedex, France.
authors.forename: Cyrille
authors.initials: C
authors.lastname: Sabot
authors.forename: Michel
authors.initials: M
authors.lastname: Mosser
authors.forename: Cyril
authors.initials: C
authors.lastname: Antheaume
authors.forename: Charles
authors.initials: C
authors.lastname: Mioskowski
authors.forename: Rachid
authors.initials: R
authors.lastname: Baati
authors.forename: Alain
authors.initials: A
authors.lastname: Wagner
mesh_terms: D000588:Amines / Q000737:chemistry*; D017879:Isothiocyanates / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008698:Mesylates / Q000138:chemical synthesis / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
chemical_list: D000588:Amines; D017879:Isothiocyanates; D008698:Mesylates; C542551:N-((2-isothiocyanato)cyclohexyl)trifluoromethanesulfonamide; C037152:isothiocyanic acid