title: Cannula-aided penetration: a simple method to insert structurally weak electrodes into brain through the dura mater.
abstract: We developed a simple and inexpensive method to insert structurally weak electrodes into the brain through the thickened dura mater in chronic animal experiments. It uses a commonly available intravenous (IV) needle and a cannula to secure a small puncture in the dura mater, through which an electrode is advanced into the underlying cerebral cortex. In addition to its simplicity and cost-effectiveness, this method provides greater degree of freedom regarding the shape and the placement of electrodes compared to the conventional guide tube systems.
authors.affiliation: Department of Physiology, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-cho, Aoba ward, Sendai 980-8575, Japan. matsuzay@mail.tains.tohoku.ac.jp
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Matsuzaka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Tetsu
authors.initials: T
authors.lastname: Tanaka
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Furusawa
authors.forename: Hajime
authors.initials: H
authors.lastname: Mushiake
mesh_terms: D000818:Animals; D002404:Catheterization / Q000295:instrumentation*; D004388:Dura Mater; D004867:Equipment Design; D008839:Microelectrodes; D009339:Needles