title: Sequence analysis of the novel HLA-Cw*08 variant allele, Cw*0820, in a Chinese Han individual.
abstract: A novel human leukocyte antigen (HLA) allele, HLA-Cw*0820, was identified in a Chinese Han individual. It differs from the closest allele Cw*080101 by single nucleotide change at genomic nucleotide (nt) 1615 G>A (coding sequence nt 652 G>A, codon 194 GTC>ATC) in exon 4, which results in an amino acid change Val194Ile.
authors.affiliation: Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China. zhihui_deng@yahoo.com.cn
authors.forename: Z-H
authors.initials: ZH
authors.lastname: Deng
authors.forename: Y-P
authors.initials: YP
authors.lastname: Xu
authors.forename: D-M
authors.initials: DM
authors.lastname: Wang
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D001854:Bone Marrow Cells / Q000166:cytology; D002681:China / Q000208:ethnology; D003001:Cloning, Molecular; D003062:Codon; D017931:DNA Primers / Q000235:genetics; D005006:Ethnicity / Q000235:genetics*; D005091:Exons; D014644:Genetic Variation; D005838:Genotype; D015236:HLA-C Antigens / Q000235:genetics*; D006239:Haplotypes; D006650:Histocompatibility Testing / Q000379:methods; D006801:Humans; D007438:Introns; D007532:Isoleucine / Q000378:metabolism; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011933:Reagent Kits, Diagnostic; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid; D009626:Terminology as Topic; D014019:Tissue Donors
chemical_list: D003062:Codon; D017931:DNA Primers; D015236:HLA-C Antigens; D011933:Reagent Kits, Diagnostic; D007532:Isoleucine