Neuropsychiatric disorders: Shared genetics of bipolar disorder and schizophrenia.
Bipolar disorder and schizophrenia share common clinical features, and antipsychotic medications can treat both conditions effectively. An assessment of 73,929 people with bipolar disorder and/or schizophrenia from a Swedish registry found evidence that the two disorders also share more than half of their genetic determinants.
Potash
James B
JB
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA. jpotash@jhmi.edu
Bienvenu
O Joseph
OJ
D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*; D005828:Genetics, Population; D055106:Genome-Wide Association Study / Q000379:methods; D006801:Humans; D008957:Models, Genetic; D012559:Schizophrenia / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*
D014150:Antipsychotic Agents