title: Resolution of (+/-)-beta-methylphenylethylamine by a novel chiral stationary phase for Pirkle-type column chromatography.
abstract: In this study, a new Pirkle-type chiral column stationary phase for resolution of beta-methylphenylethyl amine was described by using activated Sepharose 4B as a matrix, L-tyrosine as a spacer arm, and an aromatic amine derivative of L-glutamic acid as a ligand. The binding capacities of the stationary phase were determined at different pH values (pH = 6, 7, and 8) using buffer solutions as mobile phase, and enantiomeric excess (ee) was determined by HPLC equipped with chiral column. The ee was found to be 47%.
authors.affiliation: Department of Chemistry, Faculty of Education, Dicle University, Diyarbakir, Turkey.
authors.forename: Hayrullah
authors.initials: H
authors.lastname: Yilmaz
authors.forename: Giray
authors.initials: G
authors.lastname: Topal
authors.forename: Resit
authors.initials: R
authors.lastname: Cakmak
authors.forename: Halil
authors.initials: H
authors.lastname: Hosgoren