title: Recurrent epistaxis as a presenting sign of androgen-sensitive metastatic prostate cancer.
abstract: Prostate cancer is a common cancer, especially among elderly men. It is sometimes not diagnosed until it has metastasised. Disseminated intravascular coagulopathy (DIC) can be the presenting manifestation of prostate cancer, and can present with bleeding (varying from isolated epistaxis to generalised haemorrhage), intravascular thrombosis, or both. A case of recurrent epistaxis from DIC due to metastatic prostate cancer occurring in an 84-year-old Caucasian man is presented, and the pathophysiology and management of DIC in association with androgen-sensitive prostate cancer are discussed.
authors.affiliation: Division of Haematology and Oncology, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Suite 2100, Salt Lake City, Utah 84112, USA.
authors.forename: H Y
authors.initials: HY
authors.lastname: Lim
authors.forename: A M
authors.initials: AM
authors.lastname: Agarwal
authors.forename: N
authors.initials: N
authors.lastname: Agarwal
authors.forename: J H
authors.initials: JH
authors.lastname: Ward
mesh_terms: D000369:Aged, 80 and over; D000728:Androgens; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D004844:Epistaxis / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000150:complications*; D012008:Recurrence
chemical_list: D000728:Androgens