title: Intermittent positive airway pressure to manage hypoxia during one-lung anaesthesia.
abstract: The effect of intermittent positive airway pressure to the non-ventilated lung was assessed in 10 patients who desaturated during one-lung ventilation. Once their saturation fell below 95% they were given a slow inflation of 2 l/min of oxygen into the non-ventilated lung for two seconds. This was repeated every 10 seconds for five minutes or until the saturation rose to 98%, whichever was sooner. The initial mean SpO2 was 89.3% +/- 4.2%. All 10 patients had an increase in saturation. The mean saturation following intermittent positive airway pressure was 96.5% +/- 1.6% (P < 0.0001). Similarly, the mean oxygen tension rose from 67.2 +/- 12.8 mmHg to 98.9 +/- 19.8 mmHg. Intermittent positive airway pressure should be considered for patients who desaturate while undergoing one-lung ventilation.
authors.affiliation: Department of Anaesthesia, Royal Adelaide Hospital and University of Adelaide, Adelaide, South Australia, Australia.
authors.forename: W J
authors.initials: WJ
authors.lastname: Russell
mesh_terms: D000758:Anesthesia / Q000379:methods*; D001784:Blood Gas Analysis; D006801:Humans; D000860:Hypoxia / Q000517:prevention & control*; D007385:Intermittent Positive-Pressure Ventilation / Q000379:methods*; D008168:Lung / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D012121:Respiration, Artificial / Q000009:adverse effects / Q000379:methods; D013908:Thoracotomy / Q000379:methods
chemical_list: D010100:Oxygen