title: BioPortal: ontologies and integrated data resources at the click of a mouse.
abstract: Biomedical ontologies provide essential domain knowledge to drive data integration, information retrieval, data annotation, natural-language processing and decision support. BioPortal (http://bioportal.bioontology.org) is an open repository of biomedical ontologies that provides access via Web services and Web browsers to ontologies developed in OWL, RDF, OBO format and Protégé frames. BioPortal functionality includes the ability to browse, search and visualize ontologies. The Web interface also facilitates community-based participation in the evaluation and evolution of ontology content by providing features to add notes to ontology terms, mappings between terms and ontology reviews based on criteria such as usability, domain coverage, quality of content, and documentation and support. BioPortal also enables integrated search of biomedical data resources such as the Gene Expression Omnibus (GEO), ClinicalTrials.gov, and ArrayExpress, through the annotation and indexing of these resources with ontologies in BioPortal. Thus, BioPortal not only provides investigators, clinicians, and developers 'one-stop shopping' to programmatically access biomedical ontologies, but also provides support to integrate data from a variety of biomedical resources.
authors.affiliation: Stanford Center for Biomedical Informatics Research, Stanford University.
authors.forename: Natalya F
authors.initials: NF
authors.lastname: Noy
authors.forename: Nigam H
authors.initials: NH
authors.lastname: Shah
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Whetzel
authors.forename: Benjamin
authors.initials: B
authors.lastname: Dai
authors.forename: Michael
authors.initials: M
authors.lastname: Dorf
authors.forename: Nicholas
authors.initials: N
authors.lastname: Griffith
authors.forename: Clement
authors.initials: C
authors.lastname: Jonquet
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Rubin
authors.forename: Margaret-Anne
authors.initials: MA
authors.lastname: Storey
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Chute
authors.forename: Mark A
authors.initials: MA
authors.lastname: Musen
mesh_terms: D000043:Abstracting and Indexing; D035843:Biomedical Research; D020407:Internet; D009323:Natural Language Processing; D012984:Software; D018511:Systems Integration; D014584:User-Computer Interface; D018875:Vocabulary, Controlled