Cu(II)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group.
Tetrahydropyrimidine works efficiently as a directing group in Cu(ii)-mediated oxidative aromatic C-H functionalisation for the selective introduction of oxygen or nitrogen to the ortho-position.
Mizuhara
Tsukasa
T
Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Inuki
Shinsuke
S
Oishi
Shinya
S
Fujii
Nobutaka
N
Ohno
Hiroaki
H
D000814:Aniline Compounds / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D006900:Hydroxylation; D010084:Oxidation-Reduction; D011743:Pyrimidines / Q000737:chemistry*
D000814:Aniline Compounds; D011743:Pyrimidines; D002244:Carbon; D003300:Copper; D006859:Hydrogen; C023650:aniline