title: [Stroke and atrial fibrillation].
abstract: Approximately 80% of all strokes are ischemic, the remaining being hemorrhagic. The major reason for cerebral ischemia is occlusion of a cerebral artery by a cardiac thrombus in a patient with atrial fibrillation. This article focuses on the therapeutic management of patients with cerebral ischemia due to atrial fibrillation and is based on the guidelines of the German Society of Neurology and the European Stroke Organization: Patients with cerebral ischemia and atrial fibrillation require oral anticoagulation with an INR of 2.0-3.0. After a TIA (transient ischemic attack) or minor ischemic stroke, anticoagulation can be initiated within the first week after the stroke. Combination therapy of aspirin and clopidogrel is less effective than oral anticoagulation.
authors.affiliation: Neurogische Klinik, Städtisches Klinikum Karlsruhe, Moltkestrasse 90, Karlsruhe, Germany. georg.gahn@klinikum-karlsruhe.de
authors.forename: G
authors.initials: G
authors.lastname: Gahn
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000150:complications* / Q000188:drug therapy*; D002545:Brain Ischemia / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants