title: Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions.
abstract: Detection of CXCR4-using human immunodeficiency virus by the Trofile assay was compared to that by assays using virus isolates or replication-competent recombinants. Concordance with the Trofile assay was good, but assays using replicating viruses did not increase substantially the ability to detect the presence of CXCR4-using virus.
authors.affiliation: Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Hosoya
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Su
authors.forename: Timothy
authors.initials: T
authors.lastname: Wilkin
authors.forename: Roy M
authors.initials: RM
authors.lastname: Gulick
authors.forename: Charles
authors.initials: C
authors.lastname: Flexner
authors.forename: Michael D
authors.initials: MD
authors.lastname: Hughes
authors.forename: Paul R
authors.initials: PR
authors.lastname: Skolnik
authors.forename: Françoise
authors.initials: F
authors.lastname: Giguel
authors.forename: Wayne L
authors.initials: WL
authors.lastname: Greaves
authors.forename: Eoin
authors.initials: E
authors.lastname: Coakley
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Kuritzkes
mesh_terms: D015497:HIV-1 / Q000235:genetics / Q000502:physiology*; D006801:Humans; D010949:Plasma / Q000821:virology; D011991:Receptors, Virus / Q000032:analysis*; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*; D053586:Virus Internalization; D014779:Virus Replication
chemical_list: D011991:Receptors, Virus