Foreign-body-associated granulomatous slack skin in folliculotropic mycosis fungoides of childhood.
Presented in part at the XXVIII Symposium of the International Society of Dermatopathology, Paris, November 14-17, 2007. A 13-year-old boy developed a bulky mass close to the right axillary region and an infiltrated plaque on the abdominal skin. Two years earlier, the diagnosis of follicular mycosis fungoides has been established. Biopsies of both areas revealed typical features of granulomatous slack skin (GSS). Within some of the giant cells, doubly refractile material of unknown origin was found. It may be speculated that in the reported case of follicular mycosis fungoides in childhood, GSS developed as a specific reaction pattern of the disease because of foreign bodies.
Tronnier
Michael
M
Department of Dermatology, Klinikum Hildesheim GmbH, Hildesheim, Germany. m.tronnier@klinikum-hildesheim.de
D000293:Adolescent; D016588:Anticarcinogenic Agents / Q000627:therapeutic use; D000077610:Bexarotene; D002648:Child; D002675:Child, Preschool; D005547:Foreign Bodies / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009182:Mycosis Fungoides / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D012878:Skin Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D013764:Tetrahydronaphthalenes / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D013764:Tetrahydronaphthalenes; D000077610:Bexarotene