An oxazolo[3,2-b]indazole route to 1H-indazolones.
The novel heterocycle 2,3-dihydrooxazolo[3,2-b]indazole has been synthesized and utilized to provide easy access to 1H-indazolones, particularly the previously unreported 2-(2-alkoxyethyl)-1H-indazol-3(2H)-ones. Mechanistic as well as optimization and reaction scope studies are reported.
Oakdale
James S
JS
Department of Chemistry, University of California, One Shields Avenue, Davis, California 95616, USA.
Solano
Danielle M
DM
Fettinger
James C
JC
Haddadin
Makhluf J
MJ
Kurth
Mark J
MJ
D000438:Alcohols / Q000737:chemistry; D001596:Benzylamines / Q000737:chemistry; D007191:Indazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*
D000438:Alcohols; D001596:Benzylamines; D007191:Indazoles; D010080:Oxazoles