title: Anti-arthritic potential of the plant Justicia gendarussa Burm F.
abstract: OBJECTIVE
  To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models.
  
  
  METHODS
  The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin.
  
  
  RESULTS
  The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.
authors.affiliation: Department of Anatomy, Melaka Manipal Medical College, Manipal, Karnataka, India. jaijesh@yahoo.co.in
authors.forename: Jaijesh
authors.initials: J
authors.lastname: Paval
authors.forename: Srinivasan Keloth
authors.initials: SK
authors.lastname: Kaitheri
authors.forename: Bhagath Kumar
authors.initials: BK
authors.lastname: Potu
authors.forename: Sreejith
authors.initials: S
authors.lastname: Govindan
authors.forename: Raju Suresh
authors.initials: RS
authors.lastname: Kumar
authors.forename: Sareesh Naduvil
authors.initials: SN
authors.lastname: Narayanan
authors.forename: Sudheer
authors.initials: S
authors.lastname: Moorkoth
mesh_terms: D027901:Acanthaceae / Q000009:adverse effects; D000276:Adjuvants, Immunologic; D000818:Animals; D001169:Arthritis, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D002417:Cattle; D024043:Collagen Type II; D004353:Drug Evaluation, Preclinical; D005620:Freund's Adjuvant; D008517:Phytotherapy; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000276:Adjuvants, Immunologic; D024043:Collagen Type II; D010936:Plant Extracts; D005620:Freund's Adjuvant