title: Detection of small bowel slow-wave frequencies from noninvasive biomagnetic measurements.
abstract: We report a novel method for identifying the small intestine electrical activity slow-wave frequencies (SWFs) from noninvasive biomagnetic measurements. Superconducting quantum interference device magnetometer measurements are preprocessed to remove baseline drift and high-frequency noise. Subsequently, the underlying source signals are separated using the well-known second-order blind identification (SOBI) algorithm. A simple classification scheme identifies and assigns some of the SOBI components to a section of small bowel. SWFs were clearly identified in 10 out of 12 test subjects to within 0.09-0.25 cycles per minute. The method is sensitive at the 40.3 %-55.9 % level, while false positive rates were 0 %-8.6 %. This technique could potentially be used to help diagnose gastrointestinal ailments and obviate some exploratory surgeries.
authors.affiliation: Department of Physics, Vanderbilt University, Nashville, TN 37235, USA. jonathan.c.erickson@vanderbilt.edu
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Erickson
authors.forename: Chibuike
authors.initials: C
authors.lastname: Obioha
authors.forename: Adam
authors.initials: A
authors.lastname: Goodale
authors.forename: L Alan
authors.initials: LA
authors.lastname: Bradshaw
authors.forename: William O
authors.initials: WO
authors.lastname: Richards
mesh_terms: D000465:Algorithms; D000818:Animals; D004574:Electromagnetic Fields; D055724:Electrophysiological Phenomena; D005769:Gastrointestinal Motility / Q000502:physiology*; D007421:Intestine, Small / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013552:Swine