title: Treatment of acrodermatitis continua with topical 8-methoxypsoralen plus local narrowband ultraviolet B phototherapy.
abstract: Treatment of acrodermatitis continua of Hallopeau (ACH) is known to be difficult. A 24-year-old man presented with an 11-year history of recurrent flares of painful pustular and scaly lesions on the distal portion of his fingers and toes, with persistent nail dystrophy. Based on the clinical and histopathological findings, ACH was diagnosed. The patient was treated with topical 8-methoxypsoralen (8-MOP) without occlusion, plus local narrowband ultraviolet B (NB-UVB) phototherapy. The patient did not use any other medication between sessions except topical emollients. Ten weeks later, when the patient had received 20 sessions, almost all the lesions had cleared. We report the first case of ACH which successfully responded to treatment with 8-MOP/NB-UVB.
authors.affiliation: Department of Dermatology, Ministry of Health Ankara Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey. pelin@dr.com
authors.forename: Selda Pelin Kartal
authors.initials: SP
authors.lastname: Durmazlar
authors.forename: Hatice
authors.initials: H
authors.lastname: AKPINAR
authors.forename: Cemile
authors.initials: C
authors.lastname: EREN
authors.forename: Fatma
authors.initials: F
authors.lastname: ESKIOGLU
authors.forename: Semih
authors.initials: S
authors.lastname: TATLICAN
mesh_terms: D000169:Acrodermatitis / Q000188:drug therapy* / Q000473:pathology; D000287:Administration, Topical; D000328:Adult; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000008:administration & dosage*; D014467:Ultraviolet Therapy
chemical_list: D008730:Methoxsalen