title: Seroprevalence of Coxiella burnetii and Brucella abortus among pregnant women.
abstract: Coxiella burnetii and Brucella abortus are two intracellular bacteria implicated in zoonotic miscarriage. In the present study, C. burnetii and B. abortus seroprevalence was compared among women from London with and without miscarriage. Coxiella burnetii seroprevalence was high (4.6%, 95% CI 2.8-7.1) despite the rare apparent exposure of this urban population. Only two patients exhibited anti-B. abortus antibodies. As a result of the risk of chronic Q fever with endocarditis and/or hepatitis, the mode of Coxiella burnetii infection in this population merits further investigation.
authors.affiliation: Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Baud
authors.forename: O
authors.initials: O
authors.lastname: Peter
authors.forename: C
authors.initials: C
authors.lastname: Langel
authors.forename: L
authors.initials: L
authors.lastname: Regan
authors.forename: G
authors.initials: G
authors.lastname: Greub
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D002003:Brucella abortus / Q000276:immunology*; D002006:Brucellosis / Q000453:epidemiology*; D016997:Coxiella burnetii / Q000276:immunology*; D005260:Female; D006801:Humans; D008131:London / Q000453:epidemiology; D011247:Pregnancy; D037841:Pregnant People; D011778:Q Fever / Q000453:epidemiology*; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial