title: Theoretical study of immersion optical clearing of blood in vessels at local hemolysis.
abstract: Mie based theoretical analysis has been performed for investigation of the possibility of application of the plasma hemoglobin releasing due to local hemolysis for optical clearing of blood. The 30-40% reduction of the scattering coefficient of blood in the spectral range from 400 to 1000 nm with increase of degree of hemolysis (up to 20%) was shown. At the same time, the reduction of absorption coefficient of blood is localized mainly within the Soret band with maximum at 415 nm (---~15%), the alpha-band at 540 nm and the beta-band at 577 nm (~10%) of oxyhemoglobin. In the spectral range from 700 to 1000 nm the decrease of absorption coefficient is less than 8%.
authors.forename: Valery
authors.initials: V
authors.lastname: Tuchin
authors.forename: Dmitry
authors.initials: D
authors.lastname: Zhestkov
authors.forename: Alexey
authors.initials: A
authors.lastname: Bashkatov
authors.forename: Elina
authors.initials: E
authors.lastname: Genina