title: Influenza-associated central nervous system dysfunction in Taiwanese children: clinical characteristics and outcomes with and without administration of oseltamivir.
abstract: Seventy-four of the 2651 patients (2.8%) with influenza aged <18 years had signs or symptoms of central nervous system dysfunction presenting to the hospital. None had oseltamivir exposure before the onset of central nervous system dysfunction. Seventeen children received oseltamivir therapy after admission and no significant difference between administration of oseltamivir and outcome was observed (P = 0.1512 by Fisher exact test).
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, Kweishan, Taoyan, Taiwan. ychuang@adm.cgmh.org.tw
authors.forename: Yhu-Chering
authors.initials: YC
authors.lastname: Huang
authors.forename: Wen-Chen
authors.initials: WC
authors.lastname: Li
authors.forename: Kuo-Chien
authors.initials: KC
authors.lastname: Tsao
authors.forename: Chung-Guei
authors.initials: CG
authors.lastname: Huang
authors.forename: Cheng-Hsun
authors.initials: CH
authors.lastname: Chiu
authors.forename: Tzou-Yien
authors.initials: TY
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use*; D002493:Central Nervous System Diseases / Q000473:pathology* / Q000503:physiopathology / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007251:Influenza, Human / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use*; D013624:Taiwan; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir