Ascertainment of variations in the biological half-lives of bromide and sodium ions in the rat by in vivo gamma-ray measurement of 82Br and 24Na radionuclides.
With the aid of in vivo whole-body counting of the rats (administered simultaneously with the radionuclides (82)Br and (24)Na) by high-resolution gamma-ray spectrometry, we extended the applicability of our experimentally proved hypothesis that the biological half-life of bromide depends on the magnitude of sodium intake rather than on the intake of chloride, as was generally assumed. Variations in the biological half-life of bromide, as a substitute for sodium, were investigated in animals situated in very different physiological states, as regards their metabolic activity.
Pavelka
S
S
Institute of Physiology, Department of Radiometry, Academy of Sciences of the Czech Republic, v.v.i., 14220 Prague 4, Czech Republic. pavelka@biomed.cas.cz
Vobecký
M
M
Babický
A
A
D000818:Animals; D001967:Bromine Radioisotopes / Q000032:analysis*; D005260:Female; D005720:Gamma Rays; D006207:Half-Life; D007774:Lactation; D051381:Rats; D017208:Rats, Wistar; D012979:Sodium Radioisotopes / Q000032:analysis*
D001967:Bromine Radioisotopes; D012979:Sodium Radioisotopes