Ischemic stroke in Williams-Beuren syndrome: a case report.
A 15-year-old girl was admitted because of an acute onset of facial palsy and right hemiparesis. The patient had a history of moderate mental retardation and developmental delay. On admission, her vital signs were stable, except for high blood pressure. Magnetic resonance imaging demonstrated an infarct involving the left internal capsule and putamen. Because of the patient's young age, an extensive stroke survey was performed. Williams-Beuren syndrome was finally confirmed by fluorescent in situ hybridization. Compared with the previously reported cases, no evidence of cerebral arterial stenosis or cardiac abnormalities was found by noninvasive imaging techniques. Because Williams-Beuren syndrome is a complex, multiple congenital anomaly syndrome with prominent cardiovascular features, regular assessment and antihypertensive treatment are necessary to minimize the lifelong cardiovascular risk in patients with this syndrome.
Lee
Wei-Der
WD
Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Hsu
Jui-Jen
JJ
Huang
Feng-Chen
FC
Chao
Mei-Chyn
MC
Chang
Yu-Li
YL
Huang
Mao-Hsiung
MH
D000293:Adolescent; D005260:Female; D006801:Humans; D020772:Internal Capsule / Q000098:blood supply / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D011699:Putamen / Q000098:blood supply / Q000000981:diagnostic imaging; D011859:Radiography; D020521:Stroke / Q000209:etiology*; D018980:Williams Syndrome / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics