Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum.
Mutiniside (1), new phenolic glucoside, and the flavonoidal glucoside cephacoside (2) have been isolated from the n-BuOH soluble fraction, along with lupeol (3), beta-sitosterol (4), stigmasterol (5), methyl-4-hydroxybenzoate (6), taraxacin (7), ursolic acid (8), and beta-sitosterol-3-O-beta-D-glucopyranoside (9), have been isolated from the EtOAc soluble fraction of Abutilon muticum. Compounds 2-9 are reported for the first time from this species. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase.
Ali
Samar
S
Pharmaceutical Research Centre, PCSIR Laboratories Complex Karachi, Karachi, Pakistan.
Yasmeen
Shazia
S
Afza
Nighat
N
Malik
Abdul
A
Iqbal
Lubna
L
Lateef
Mehreen
M
Riaz
Naheed
N
Ashraf
Muhammad
M
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019660:Malvaceae / Q000737:chemistry*; D015394:Molecular Structure; D010154:Pakistan; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D016859:Lipoxygenase Inhibitors; D010636:Phenols; D010851:Picrates; D012855:Sitosterols; C541316:mutiniside; C472604:sitosterol-3-O-glucopyranoside; C025473:gamma-sitosterol; C004931:1,1-diphenyl-2-picrylhydrazyl