title: Association between familial mediterranean fever and retroperitoneal fibrosis: retroperitoneal fibrosis regression after colchicine therapy.
abstract: Retroperitoneal fibrosis (RPF) is a disease characterized by inflammatory fibrotic processes affecting the retroperitoneal structures. Familial Mediterranean Fever (FMF) is an autosomal recessive disorder, characterized by fever and attacks of sterile serositis. Colchicine is the only suitable drug for prevention of acute episodes. We describe a case of association between RPF and FMF in a 48-year-old male, in whom therapy with colchicine, besides preventing acute episodes, allowed RPF regression. To date the association between FMF and RPF and the use of colchicine therapy alone for RPF has not been described.
authors.forename: G
authors.initials: G
authors.lastname: De Socio
authors.forename: C
authors.initials: C
authors.lastname: Cerquaglia
authors.forename: V
authors.initials: V
authors.lastname: Curigliano
authors.forename: C
authors.initials: C
authors.lastname: Fonnesu
authors.forename: M
authors.initials: M
authors.lastname: Giovinale
authors.forename: E
authors.initials: E
authors.lastname: Verrecchia
authors.forename: G M E
authors.initials: GM
authors.lastname: Marino
authors.forename: L
authors.initials: L
authors.lastname: Natale
authors.forename: G B
authors.initials: GB
authors.lastname: Gasbarrini
authors.forename: R
authors.initials: R
authors.lastname: Manna
mesh_terms: D003078:Colchicine / Q000627:therapeutic use*; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D012185:Retroperitoneal Fibrosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003078:Colchicine