title: Model-based iterative reconstruction for radial fast spin-echo MRI.
abstract: In radial fast spin-echo magnetic resonance imaging (MRI), a set of overlapping spokes with an inconsistent T2 weighting is acquired, which results in an averaged image contrast when employing conventional image reconstruction techniques. This work demonstrates that the problem may be overcome with the use of a dedicated reconstruction method that further allows for T2 quantification by extracting the embedded relaxation information. Thus, the proposed reconstruction method directly yields a spin-density and relaxivity map from only a single radial data set. The method is based on an inverse formulation of the problem and involves a modeling of the received MRI signal. Because the solution is found by numerical optimization, the approach exploits all data acquired. Further, it handles multicoil data and optionally allows for the incorporation of additional prior knowledge. Simulations and experimental results for a phantom and human brain in vivo demonstrate that the method yields spin-density and relaxivity maps that are neither affected by the typical artifacts from TE mixing, nor by streaking artifacts from the incomplete k-space coverage at individual echo times.
authors.affiliation: Biomedizinische NMR Forschungs GmbH, 37077 Göttingen, Germany.
authors.forename: Kai Tobias
authors.initials: KT
authors.lastname: Block
authors.forename: Martin
authors.initials: M
authors.lastname: Uecker
authors.forename: Jens
authors.initials: J
authors.lastname: Frahm
mesh_terms: D000465:Algorithms; D001931:Brain Mapping / Q000379:methods; D017352:Echo-Planar Imaging / Q000379:methods*; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008962:Models, Theoretical; D019047:Phantoms, Imaging