title: [Evaluation of chronic obstructive pulmonary disease screening in a high risk population].
abstract: OBJECTIVE
  To investigate the results of spirometry testing used in the screening of COPD from at risk populations.
  
  
  METHODS
  A survey of the population aged over 40 years with any of chronic cough and sputum, dyspnea, heavy tobacco smoke was performed, using a questionnaire on clinical characteristics of COPD. Spirometry and chest X ray examination were performed. Different screening methods were compared for sensitivity and specificity for COPD diagnosis.
  
  
  RESULTS
  Of 241 surveyed persons, 156 were diagnosed as having COPD, among whom 126 cases were firstly diagnosed. Among all surveyed persons, 87 (36. 1%) cases had mild and moderate COPD, while 69 (28. 6%) had severe and very severe disease. The sensitivity and specificity for diagnosis of COPD of shortness of breath were 61.5% and 61.2% respectively. Combination of respiratory symptoms and risk factors improved the screening power. More than 40 years of age combined with any of heavy smoking, chronic cough and sputum, or shortness of breath, improved the sensitivity to more than 90 percent.
  
  
  CONCLUSIONS
  Spirometry test screening of the at risk population can effectively improve early diagnosis of COPD.
authors.affiliation: Respiratory Department of People's Hospital Peking University, Beijing 100044, China.
authors.forename: Rong-Bao
authors.initials: RB
authors.lastname: Zhang
authors.forename: Quan-Ying
authors.initials: QY
authors.lastname: He
authors.forename: Xing-Yu
authors.initials: XY
authors.lastname: Tan
authors.forename: Rui-Hong
authors.initials: RH
authors.lastname: Yang
authors.forename: Xue-Liang
authors.initials: XL
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012907:Smoking; D013147:Spirometry