A short stereoselective synthesis of (+)-(6R,2'S)-cryptocaryalactone via ring-closing metathesis.
A short stereoselective synthesis of (+)-(6R,2'S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira's asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.
Radha Krishna
Palakodety
P
D-206/B, Discovery Laboratory, Organic Chemistry Division-III, Indian Institute of Chemical Technology, Hyderabad-500 607, India. prkgenius@iict.res.in
Lopinti
Krishnarao
K
Reddy
K L N
KL