Is there a current role for preoperative non-absorbable oral antimicrobial agents for prophylaxis of infection after colorectal surgery?
BACKGROUND
In numerous scientific studies, oral antibiotic bowel preparation has reduced surgical site infections in patients undergoing colorectal surgery. The historical evolution of antibiotic bowel preparation is presented with a review of the scientific basis of its effectiveness.


METHODS
Review of the pertinent English language literature.


RESULTS
Successful oral antibiotic bowel preparation requires effective mechanical preparation. The progressive shift of preoperative preparation to the outpatient setting has led to a reduction in the use of oral antibiotics. Such preparation, however, continues to be effective although in current surgical practice is often augmented with perioperative, parenteral antimicrobials.


CONCLUSIONS
Oral antibiotic bowel preparation has a role in the prevention of surgical site infection in the patient undergoing colorectal surgery.
Hayashi
Michael S
MS
Department of Surgery, University of California-Irvine School of Medicine, Orange, California 92868, USA.
Wilson
Samuel Eric
SE
D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D003107:Colorectal Surgery / Q000009:adverse effects*; D006801:Humans; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents