The influence of fitness on insulin resistance in obese children.
An increasingly pervasive environment of reduced activity and easy access to high caloric food is leading to an epidemic of poor cardiovascular fitness, obesity, insulin resistance and type 2 diabetes (T2DM) in children. Studies have shown that insulin resistance (IR) to be an independent predictor for morbidity as well as mortality. These serve as a strong stimulus for public health strategies to improve fitness in children and adolescents. Methods to assess IR, improve IR and understand complications are increasingly important in children.
Carrel
Aaron L
AL
Department of Pediatrics, American Family Children's Hospital, University of Wisconsin, Madison, WI 53792, USA. alcarrel@wisc.edu
Allen
David B
DB
D002648:Child; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D024821:Metabolic Syndrome / Q000150:complications; D008962:Models, Theoretical; D009765:Obesity / Q000150:complications*; D010809:Physical Fitness / Q000502:physiology*