title: Interest of 50% nitrous oxide and oxygen premix sedation in gerodontology.
abstract: Elderly patients presenting cardiovascular, respiratory, or neurological disorders require a specific dental care approach, especially patients presenting Alzheimer's disease. Sedative procedures can prevent dental care-induced stress, even when there is effective pain control, but they have to be adapted to accommodate age-induced physiological modifications, age-related pathologies, and the concomitant treatments. In many situations, routine sedative prescriptions for dental care, such as benzodiazepine or antihistaminics, are not recommended for these patients. Nitrous oxide inhalation together with a specific behavioral threshold is currently the only sedative procedure adapted to cognitively-impaired elderly patients. Nitrous oxide is able to curb stress and its cardiovascular consequences, improve oxygenation, and optimize cooperation during dental care, making not only rehabilitation treatments but also routine dental care a viable option.
authors.affiliation: CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France. emmanuel.nicolas@u-clermont1.fr
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Nicolas
authors.forename: Claire
authors.initials: C
authors.lastname: Lassauzay
mesh_terms: D000368:Aged; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000627:therapeutic use*; D002318:Cardiovascular Diseases; D003072:Cognition Disorders; D016292:Procedural Sedation / Q000379:methods; D003704:Dementia; D016321:Dental Care for Aged / Q000523:psychology; D004361:Drug Tolerance; D005602:France; D006801:Humans; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000627:therapeutic use*; D010100:Oxygen / Q000008:administration & dosage*
chemical_list: D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide; D010100:Oxygen