title: Validation of capillary glycemia as a strategy for the screening of diabetes mellitus in adolescents.
abstract: OBJECTIVE
  To compare the degree of concordance between plasma and capillary glucose for screening of diabetes mellitus in adolescents.
  
  
  METHODS
  The plasma and capillary glucose of 119 adolescents aged 10-19 yr (36 males and 83 females) from public schools in Niterói, Rio de Janeiro State, Brazil, were verified after a 12-h fast. Agreement was assessed through kappa statistics (k), McNemar's chi-squared test, and the intraclass correlation coefficient (ICC). The paired Student's t-test for comparison of means, the approaches by Altman and Bland, and the survival-agreement plot were also applied.
  
  
  RESULTS
  Mean values of plasma glucose were 7.9 points higher than the capillary values (91.5 vs. 83.6 mg/dL, p < 0.001; ICC = 0.419). A regular agreement between the methods (k = 0.31, p < 0.001) for assessing proportions of adolescents with glycemia > or =100 mg/dL is observed. Using the strategy of adding 8 mg/dL to the capillary levels, the agreement improved (k = 0.46, p < 0.001) and a significant difference was not observed between the estimated prevalences (p = 0.815).
  
  
  CONCLUSIONS
  The results suggest a satisfactory agreement between the two methods when capillary glucose is corrected, and this may be a useful and low-cost tool for the epidemiologic investigation of diabetes mellitus prevalence in adolescents.
authors.affiliation: Department of Nutrition, Instituto de Nutrição Josué de Castro, CCS, Universidade Federal do Rio de Janeiro, 21941-598 Rio de Janeiro, RJ, Brazil.
authors.forename: Marlene Merino
authors.initials: MM
authors.lastname: Alvarez
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Reiff e Vieira
authors.forename: Ronir Raggio
authors.initials: RR
authors.lastname: Luiz
authors.forename: Glória Valéria
authors.initials: GV
authors.lastname: da Veiga
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism*; D001938:Brazil; D002196:Capillaries / Q000502:physiology* / Q000503:physiopathology; D002648:Child; D003920:Diabetes Mellitus / Q000097:blood* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000453:epidemiology; D008403:Mass Screening / Q000379:methods*; D009752:Nutritional Status; D009765:Obesity / Q000453:epidemiology; D050177:Overweight / Q000453:epidemiology; D011336:Probability; D015203:Reproducibility of Results; D012741:Sexual Maturation; D055815:Young Adult
chemical_list: D001786:Blood Glucose