title: Effective synthesis of optically active trifluoromethyldiazirinyl homophenylalanine and aroylalanine derivatives with the Friedel-Crafts reaction in triflic acid.
abstract: The Friedel-Crafts reaction with 3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine and optically active N-TFA-Asp(Cl)-OMe in triflic acid afforded homophenylalanine derivatives without any loss of the optical purity.
authors.affiliation: Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Murashige
authors.forename: Yuta
authors.initials: Y
authors.lastname: Murai
authors.forename: Yasumaru
authors.initials: Y
authors.lastname: Hatanaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Hashimoto
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D002851:Chromatography, High Pressure Liquid; D008698:Mesylates / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D008698:Mesylates; C012077:trifluoromethanesulfonic acid; D000409:Alanine