title: [Non pulsatile active bleeding from the gastrointestinal mucosa without ulceration during anticoagulation therapy -consideration on bleeding from angiodysplasia during anticoagulation therapy-].
abstract: We reported 3 cases of the uncommon type of persistent gastrointestinal bleeding during anticoagulation therapy due to cardiovascular disorders or collagen disease. Endoscopic observation showed non pulsatile active bleeding from apparently normal mucosa, without any ulcer or obvious vascularectasia. The outflow of bleeding was string-like and continuous. Based on previous reports, we considered the possibly of these cases unique bleeding angiodysplasia and angiodysplasia during anticoagulation therapy. The frequency of this type of bleeding may increase, as anticoagulation therapy has become more common. We should pay attention to such lesions when we treat gastrointestinal bleeding.
authors.affiliation: Department of Gastroenterology, Yamagata University School of Medicine.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sato
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Takeda
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Orii
authors.forename: Sayaka
authors.initials: S
authors.lastname: Otake
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Fujishima
authors.forename: Shoichi
authors.initials: S
authors.lastname: Nishise
authors.forename: Yu
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Sumio
authors.initials: S
authors.lastname: Kawata
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000150:complications*; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008875:Middle Aged; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin