title: Spectral domain optical coherence tomography of combined hamartoma of the retina and retinal pigment epithelium.
abstract: A 17-year-old girl presented with slow, progressive, painless visual deterioration in the left eye. Fundus examination and fluorescein angiography findings were consistent with combined hamartoma of the retina and retinal pigment epithelium. Spectral domain optical coherence tomography (SD-OCT) displayed a preretinal membrane, retinal disorganization, and thickened retina drawn into folds. Partial posterior vitreous detachment was noted. The higher-resolution scans delineated the transition between the tumor and normal retina. The higher resolution of SD-OCT allows detailed observation of the vitreoretinal interface abnormalities and retinal disorganization present in combined hamartomas of the retina and retinal pigment epithelium and aids in the differential diagnosis and management of pigmented fundus lesions.
authors.affiliation: Department of Ophthalmology, University of Missouri Kansas City School of Medicine, Missouri 64108, USA.
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Huot
authors.forename: Komal B
authors.initials: KB
authors.lastname: Desai
authors.forename: Vinay A
authors.initials: VA
authors.lastname: Shah
mesh_terms: D000293:Adolescent; D019773:Epiretinal Membrane / Q000175:diagnosis; D005260:Female; D005451:Fluorescein Angiography; D005583:Fourier Analysis; D006222:Hamartoma / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D012164:Retinal Diseases / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D041623:Tomography, Optical Coherence; D020255:Vitreous Detachment / Q000175:diagnosis