title: Practical aspects of treatment discontinuation and adherence.
abstract: Hypertension control in populations, although improving, remains far from satisfactory, even though effective and inexpensive therapies are available. Among many factors responsible for this situation, poor adherence to treatment appears to be particularly important. Unfortunately, even if its causes have been quite well defined, this problem is still far from being solved in clinical practice. The present paper discusses the key issues related to treatment adherence, and discontinuation in hypertension, in the light of recent evidence coming from the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET) and Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease trial (TRANSCEND).
authors.affiliation: Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Italy. gianfranco.parati@unimib.it
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Parati
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Bilo
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D010349:Patient Compliance
chemical_list: D000959:Antihypertensive Agents