NPR1 in Plant Defense: It's Not over 'til It's Turned over.
NPR1 is a key transcriptional coregulator in plant defense responses. In this issue, Spoel et al. (2009) demonstrate that proteasome-mediated degradation of NPR1 in the nucleus promotes efficient expression of defense response genes following infection and prevents spurious activation of defensive responses in the absence of infection.
Mukhtar
M Shahid
MS
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Nishimura
Marc T
MT
Dangl
Jeff
J
D017360:Arabidopsis / Q000235:genetics / Q000276:immunology*; D029681:Arabidopsis Proteins / Q000276:immunology* / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism
D029681:Arabidopsis Proteins; C105496:NPR1 protein, Arabidopsis; D046988:Proteasome Endopeptidase Complex