title: Vascular ultrasound studies for the non-invasive assessment of vascular flow and patency in experimental surgery in the pig.
abstract: Vascular ultrasound is a reliable non-invasive tool used for the routine assessment of vascular flow and patency in human recipients. We describe the use at three different time points (immediately, 1 week and 4 weeks postsurgery) of ultrasound studies and its validation by angiographic studies in 37 swine undergoing carotid graft replacement. We calculated predictive values (>92%), sensitivity (>85%) and specificity (>92%) with high results at all time points. Ultrasound appeared as an accessible non-invasive technique, providing rapid, safe, repeatable and reliable results. It is an excellent alternative to angiography, avoiding risks inherent to invasive methods and therefore contributing to animal welfare.
authors.affiliation: Service of Cardiology, Department of Pediatrics, The Children's Hospital of Denver, University of Colorado Denver & Health Sciences Center Denver, Denver, CO, USA. osoriolujan.suzanne@tchden.org
authors.forename: S M
authors.initials: SM
authors.lastname: Osorio-da Cruz
authors.forename: Y
authors.initials: Y
authors.lastname: Aggoun
authors.forename: M
authors.initials: M
authors.lastname: Cikirikcioglu
authors.forename: E
authors.initials: E
authors.lastname: Khabiri
authors.forename: K
authors.initials: K
authors.lastname: Djebaili
authors.forename: A
authors.initials: A
authors.lastname: Kalangos
authors.forename: B
authors.initials: B
authors.lastname: Walpoth
mesh_terms: D000818:Animals; D001807:Blood Vessel Prosthesis / Q000662:veterinary; D019917:Blood Vessel Prosthesis Implantation / Q000662:veterinary; D002339:Carotid Arteries / Q000473:pathology / Q000601:surgery; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000662:veterinary*; D018810:Magnetic Resonance Angiography / Q000662:veterinary; D019060:Minimally Invasive Surgical Procedures / Q000662:veterinary*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012039:Regional Blood Flow / Q000502:physiology*; D013522:Surgery, Veterinary / Q000379:methods*; D013552:Swine; D018608:Ultrasonography, Doppler / Q000662:veterinary*; D014654:Vascular Patency / Q000502:physiology*