title: Validation of a fluid-structure interaction numerical model for predicting flow transients in arteries.
abstract: Fluid-structure interaction (FSI) numerical models are now widely used in predicting blood flow transients. This is because of the importance of the interaction between the flowing blood and the deforming arterial wall to blood flow behaviour. Unfortunately, most of these FSI models lack rigorous validation and, thus, cannot guarantee the accuracy of their predictions. This paper presents the comprehensive validation of a two-way coupled FSI numerical model, developed to predict flow transients in compliant conduits such as arteries. The model is validated using analytical solutions and experiments conducted on polyurethane mock artery. Flow parameters such as pressure and axial stress (and precursor) wave speeds, wall deformations and oscillating frequency, fluid velocity and Poisson coupling effects, were used as the basis of this validation. Results show very good comparison between numerical predictions, analytical solutions and experimental data. The agreement between the three approaches is generally over 95%. The model also shows accurate prediction of Poisson coupling effects in unsteady flows through flexible pipes, which up to this stage have only being predicted analytically. Therefore, this numerical model can accurately predict flow transients in compliant vessels such as arteries.
authors.affiliation: School of Electrical, Electronics and Mechanical Engineering, University College Dublin, Ireland. valentine.kanyanta@ucd.ie
authors.forename: V
authors.initials: V
authors.lastname: Kanyanta
authors.forename: A
authors.initials: A
authors.lastname: Ivankovic
authors.forename: A
authors.initials: A
authors.lastname: Karac
mesh_terms: D000465:Algorithms; D001158:Arteries / Q000473:pathology; D001783:Blood Flow Velocity / Q000502:physiology*; D003198:Computer Simulation; D004730:Endothelium, Vascular / Q000473:pathology; D018056:Hemorheology; D006801:Humans; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D009991:Oscillometry; D011140:Polyurethanes / Q000737:chemistry; D011312:Pressure; D011673:Pulsatile Flow / Q000502:physiology
chemical_list: D011140:Polyurethanes