[A clinical study of admitted the review of cases of food-dependent exercise-induced anaphylaxis].
BACKGROUND
Food-dependent exercise-induced anaphylaxis (FDEIA) is characterized by anaphylactic symptoms after eating certain foods, followed by exercise. As we examine more patients who have pollinosis, we have more opportunities to see allergic disease such as FDEIA, OAS, and so on.


METHODS
We performed a retrospective analysis of six cases, diagnosed FDEIA for this three years.


RESULTS
Of six cases, the ages are 8 to 47 years old, and the trigger allergens were wheat, shrimp, and grapefruit. The trigger exercises were running, volleyball, as well as taking a bath. In four cases, the patients had history of allergic disease such as atopic dermatitis, allergic rhinitis, and so on. In two cases of wheat-dependent exercise-induced anaphylaxis, the IgE levels for omega5-gliadin (a major wheat allergen) in a RAST were positive.


CONCLUSIONS
Of six cases diagnosed FDEIA, the trigger allergens were wheat, shrimp, and grapefruit. In cases of wheat-dependent exercise-induced anaphylaxis, the IgE levels for omega5-gliadin in a RAST were positive. After the food allergen has been identified, we advised strict restrictions on ingestion of trigger allergens in the case of shrimp and grapefruit, and on any exercise after eating foods containing wheat flour in the case of wheat.
Matsumoto
Ryosuke
R
Division of ENT, Himeji St. Mary's Hospital. matsumoto@himemaria.or.jp
Ogawa
Teruhiro
T
Makino
Takuma
T
Okano
Mitsuhiro
M
D000293:Adolescent; D000328:Adult; D000485:Allergens; D000707:Anaphylaxis / Q000209:etiology*; D002648:Child; D015444:Exercise; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D000485:Allergens