Seroepidemiological study of norovirus infection in Aichi Prefecture, Japan.
The serological prevalence of IgG antibody to seven NoV strains (GI.1, GI.4, GII.3, GII.4, GII.10, GII.12 and GII.15) among inhabitants aged 1-62 years of Aichi Prefecture, Japan was studied. Age-related seroprevalence was measured by ELISA using baculovirus-expressed recombinant VLP antigens. Seropositive rates for all seven VLP antigens gradually increased with age. Among the tested antigens, the highest seropositive rate was for the GII.4 strain. This result is consistent with the recent epidemic of NoV infection due to GII.4 strain in Japan.
Kobayashi
Shinichi
S
Laboratory of Virology, Department of Microbiology and Medical Zoology, Aichi Prefectural Institute of Public Health, 7-6 Nagare, Tsujimachi, Kita-ku, Nagoya 462-8576, Japan. shinichi_kobayashi@pref.aichi.lg.jp
Fujiwara
Noriko
N
Takeda
Naokazu
N
Minagawa
Hiroko
H
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000276:immunology; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000145:classification / Q000276:immunology*; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014771:Virion / Q000276:immunology; D055815:Young Adult
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G