title: Ocular complications of cancer therapy: a primer for the ophthalmologist treating cancer patients.
abstract: OBJECTIVE
  Cancer patients may develop ocular complications secondary to direct or metastatic involvement with cancer, radiation exposure, or chemotherapy. As many as 1.4 million new cancer cases arise in the United States annually.
  
  
  RESULTS
  Chemotherapy administration remains a critical aspect of treating many cancers and offers improved prognosis and prolonged survival in many cases; however, these therapies are known to cause a wide range of toxicities.
  
  
  CONCLUSIONS
  Ocular side effects such as photophobia, cataracts, glaucoma, retinopathy, and other ocular toxicities have been reported following chemotherapy administration. To effectively treat cancer patients, oncologists, primary care clinicians, and ophthalmologists should be aware of the potential ophthalmic toxicities certain widely used chemotherapeutic agents and radiation therapy may pose to their patients, particularly in the setting of preexisting ocular conditions.
authors.affiliation: Faculty of Arts and Sciences, Harvard University, Cambridge, Massachusetts, USA.
authors.forename: Ribhi
authors.initials: R
authors.lastname: Hazin
authors.forename: Jamil Y
authors.initials: JY
authors.lastname: Abuzetun
authors.forename: Yassine J
authors.initials: YJ
authors.lastname: Daoud
authors.forename: Maysa M
authors.initials: MM
authors.lastname: Abu-Khalaf
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D005128:Eye Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D011832:Radiation Injuries / Q000209:etiology; D011839:Radiation, Ionizing
chemical_list: D000970:Antineoplastic Agents