Postirradiation osteosarcoma of the maxilla: a case report and current review of literature.
Background. Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy. They are of rare occurrence in jaw bones and are even rarer in the maxilla. Case report. We report a case of radiation-induced osteosarcoma involving the maxilla in a patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago. Despite neoadjuvant chemotherapy, surgical treatment could not be performed, and the patient received palliative chemotherapy. Conclusions. Radiation-induced osteosarcomas are aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention.
Chabchoub
Imene
I
Department of Medical Oncology, University Hospital Farhat Hached, Sousse 4000, Tunisia.
Gharbi
Olfa
O
Remadi
Sami
S
Limem
Sami
S
Trabelsi
Amel
A
Hochlef
Makrem
M
Ben Fatma
Leila
L
Landolsi
Amel
A
Mokni
Moncef
M
Kraiem
Chekib
C
Ben Ahmed
Slim
S