Patient-reported outcomes in patients with endocrine tumors of the ileum.
BACKGROUND
Patients with ileal endocrine tumors have a good survival rate.


OBJECTIVE
To assess the quality of life of patients with endocrine tumors of the ileum.


METHODS
Forty-four consecutive patients (30 males, 14 females, mean age 61.1 years, range 26-79) with proven endocrine tumor of the ileum were studied.


METHODS
Italian version of the SF-12 Health Survey (SF-12) questionnaire able to explore the physical and mental aspects of daily life were used. Forty-four sex-matched and age-matched Italian normative participants were also considered for SF-12 evaluation.


RESULTS
The overall analysis of the SF-12 questionnaire in the 44 patients showed values of physical component summary (PCS) and mental component summary (MCS) scores representative of a relatively good quality of life and not significantly different from those of the normative population (PCS: 46.5+/-10.3 vs. 47.0+/-4.7, P = 0.792; MCS: 45.9+/-10.8 vs. 49.1+/-2.0, P = 0.057). PCS was significantly impaired in nonsmokers (P = 0.028), in those who underwent less invasive surgery (P = 0.007), in those who had pain at onset of the disease (P = 0.002), and in those who received multimodality treatment (P = 0.013). To evaluate the factors independently related to PCS, a multivariate analysis was performed and we found that specific surgery (P = 0.046) and presence of pain at onset of the disease (P = 0.001) were the only two factors that showed an independent relationship with PCS.


CONCLUSIONS
The patients with endocrine tumor of the ileum seem to perceive their quality of life as relatively good.
Pezzilli
Raffaele
R
Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. raffaele.pezzilli@aosp.bo.it
Campana
Davide
D
Morselli-Labate
Antonio M
AM
Galassi
Eleonora
E
Brocchi
Emilio
E
Nori
Francesca
F
Cipollini
Maria Luigia
ML
Tomassetti
Paola
P
D000328:Adult; D000368:Aged; D004701:Endocrine Gland Neoplasms / Q000523:psychology*; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000453:epidemiology; D017060:Patient Satisfaction; D011788:Quality of Life; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult