Coinfection of parvovirus b19 with other hepatitis viruses leading to fulminant hepatitis of unfavorable outcome in children.
Fulminant hepatic failure (FHF) associated with parvovirus B19 (B19) infection has a favorable prognosis in children. However, there is no data available to predict outcome in cases of FHF associated with hepatotropic virus coinfection. Clinical characteristics of 3 pediatric groups with FHF were compared and it was observed that B19 coinfection with other viruses adds to the severity of the disease and increases the probability of a fatal outcome.
Dwivedi
Mayank
M
Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India.
Manocha
Harmesh
H
Tiwari
Soumya
S
Tripathi
Gaurav
G
Dhole
T N
TN
D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D005260:Female; D006518:Hepatitis Viruses / Q000302:isolation & purification*; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000453:epidemiology* / Q000401:mortality / Q000821:virology; D006801:Humans; D017114:Liver Failure, Acute / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000821:virology*; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications* / Q000453:epidemiology* / Q000401:mortality / Q000821:virology; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D016896:Treatment Outcome