title: Fibrin glue sealing in the treatment of a recto-urethral fistula in Crohn's disease: a case report.
abstract: Recto-urethral fistulas in Crohn's disease are rare, and managing them is difficult. The various surgical techniques are not reliably effective and are associated with a significant risk of morbidity. The rectal mucosal transposition flap technique, which is used most frequently, requires the rectal mucosa to be in a healthy condition. We report here on a case where treatment was by injecting fibrin glue into a complex fistula with a single anorectal point of origin but combining a median recto-urethrocutaneous tract with two deep lateral rectoperineal tracts. The patient had presented with active rectal Crohn's disease. This treatment produced complete closure, verified by MRI, of all the fistula tracts, which was still maintained after three years, and with normal anal continence. When confronted with this type of fistula, and particularly when the condition of the rectal mucosa is poor, the specialist should be encouraged by this good result to consider the injection of fibrin glue, a technique without risk of morbidity, as a first course of action.
authors.affiliation: Service de proctologie médico-interventionnelle, groupe hospitalier Diaconesses Croix-Saint-Simon, 18 rue du Sergent Bauchat, Paris, France. etienney.i@voila.fr
authors.forename: I
authors.initials: I
authors.lastname: Etienney
authors.forename: N
authors.initials: N
authors.lastname: Rabahi
authors.forename: C-A
authors.initials: CA
authors.lastname: Cuenod
authors.forename: P
authors.initials: P
authors.lastname: Hoffmann
authors.forename: A
authors.initials: A
authors.lastname: Charachon
authors.forename: P
authors.initials: P
authors.lastname: Bauer
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D012003:Rectal Fistula / Q000209:etiology* / Q000628:therapy*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014522:Urethral Diseases / Q000209:etiology* / Q000628:therapy*; D014548:Urinary Fistula / Q000209:etiology* / Q000628:therapy*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives