Association between patient age at the time of surgical treatment for endometriosis and aryl hydrocarbon receptor repressor polymorphism.
A cross-sectional comparative study among women who underwent surgical treatment for endometriosis revealed that frequency of the Ala/Ala genotype at aryl hydrocarbon receptor repressor (AHRR) Pro185Ala polymorphism was three times higher (27.6% vs. 9.9%) in the younger group (<or=30 years) than in the older group (>30 years). AHHR genotyping may help to identify a subpopulation of women who are susceptible to the earlier onset of endometriosis.
Asada
Hironori
H
Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Yagihashi
Tatsuhiko
T
Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
Furuya
Masataka
M
Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Kosaki
Kenjiro
K
Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan. Electronic address: kkosaki@sc.itc.keio.ac.jp.
Takahashi
Takao
T
Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
Yoshimura
Yasunori
Y
Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D051792:Basic Helix-Loop-Helix Proteins; D004715:Endometriosis / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics* / Q000601:surgery; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D012097:Repressor Proteins / Q000235:genetics*; D014591:Uterine Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics* / Q000601:surgery; D055815:Young Adult
D051792:Basic Helix-Loop-Helix Proteins; D012097:Repressor Proteins; C492162:AHRR protein, human