Vanishing glioblastoma after corticosteroid therapy.
A recurrent right temporal glioblastoma that vanished on MRI after a short course of intense corticosteroid therapy is reported. This was associated with development of new multicentric lesions in the right frontal lobe and right splenium of the corpus callosum. Rapid disappearance of tumor with steroid therapy is frequently associated with lymphoma and is rarely described in high-grade gliomas. Literature review showed that multicentricity and involvement of the corpus callosum are common features of glioblastoma that vanish after corticosteroid therapy.
Goh
Jia Jun
JJ
Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
See
Siew Ju
SJ
Ang
Emily
E
Ng
Wai Hoe
WH
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D003337:Corpus Callosum / Q000473:pathology; D003907:Dexamethasone / Q000627:therapeutic use*; D017809:Fatal Outcome; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D005909:Glioblastoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged
D000893:Anti-Inflammatory Agents; D003907:Dexamethasone