title: N-acylation of ethanolamine using lipase: a chemoselective catalyst.
abstract: The N-acylation of ethanolamine (2) with various fatty acids 1a-d and esters of fatty acids 1e-h using Candida antarctica B lipase (Novozym((R)) 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation.
authors.affiliation: Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007, India. kidwai.chemistry@gmail.com
authors.forename: Mazaahir
authors.initials: M
authors.lastname: Kidwai
authors.forename: Roona
authors.initials: R
authors.lastname: Poddar
authors.forename: Poonam
authors.initials: P
authors.lastname: Mothsra