Prevalence of precancerous skin lesions and non-melanoma skin cancer in Japanese-Brazilians in Bauru, São Paulo State, Brazil.
Precancerous lesions and skin cancer are infrequent in Asians, and have received little documentation in the literature. Brazil has the world's largest contingent of Japanese immigrants and their descendants, and 70% live in the State of São Paulo. The prevalence of such skin lesions in Japanese-Brazilians is unknown. This study aimed to assess the prevalence of actinic keratoses and non-melanoma skin cancer in first and second-generation Japanese-Brazilians over 30 years of age, without miscegenation, living in the city of Bauru, São Paulo State, in 2006. Of the 567 Japanese-Brazilians that underwent dermatological examination, actinic keratosis was diagnosed in 76, with a mean age of 68.9 years, and a single case of basal cell carcinoma was detected in a 39-year-old female patient. In Japan, prevalence of actinic keratosis varies from 0.76% to 5%, and the incidence of non-melanoma skin cancer is 1.2 to 5.4/100 thousand. Japanese-Brazilians from Bauru showed a 13.4% prevalence of actinic keratoses and earlier age at onset. Proximity to the Equator and a history of farming contribute to these higher rates. Presence of solar melanosis was associated with a 1.9-fold risk of developing actinic keratosis.
Ishioka
Priscila
P
Departamento de Dermatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brasil. pishioka@uol.com.br
Marques
Sílvio Alencar
SA
Hirai
Amélia Toyomi
AT
Marques
Mariangela E A
ME
Hirata
Sérgio Henrique
SH
Yamada
Sérgio
S
D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002280:Basal Cell Carcinoma / Q000453:epidemiology* / Q000208:ethnology; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D007564:Japan / Q000208:ethnology; D055623:Keratosis, Actinic / Q000453:epidemiology* / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000208:ethnology