Anaesthesia and myocardial ischaemia/reperfusion injury.
Anaesthetists are confronted on a daily basis with patients with coronary artery disease, myocardial ischaemia, or both during the perioperative period. Therefore, prevention and ultimately adequate therapy of perioperative myocardial ischaemia and its consequences are the major challenges in current anaesthetic practice. This review will focus on the translation of the laboratory evidence of anaesthetic-induced cardioprotection into daily clinical practice.
Frässdorf
J
J
Departement of Anesthesiology, AMC-University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. j.frassdorf@amc.uva.nl
De Hert
S
S
Schlack
W
W
D000758:Anesthesia / Q000379:methods; D000777:Anesthetics / Q000627:therapeutic use*; D018685:Anesthetics, Inhalation / Q000627:therapeutic use; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D019157:Ischemic Preconditioning, Myocardial / Q000379:methods; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D019990:Perioperative Care / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control
D000777:Anesthetics; D018685:Anesthetics, Inhalation; D002316:Cardiotonic Agents