title: Seroepidemiological study of norovirus infection in Aichi Prefecture, Japan.
abstract: The serological prevalence of IgG antibody to seven NoV strains (GI.1, GI.4, GII.3, GII.4, GII.10, GII.12 and GII.15) among inhabitants aged 1-62 years of Aichi Prefecture, Japan was studied. Age-related seroprevalence was measured by ELISA using baculovirus-expressed recombinant VLP antigens. Seropositive rates for all seven VLP antigens gradually increased with age. Among the tested antigens, the highest seropositive rate was for the GII.4 strain. This result is consistent with the recent epidemic of NoV infection due to GII.4 strain in Japan.
authors.affiliation: Laboratory of Virology, Department of Microbiology and Medical Zoology, Aichi Prefectural Institute of Public Health, 7-6 Nagare, Tsujimachi, Kita-ku, Nagoya 462-8576, Japan. shinichi_kobayashi@pref.aichi.lg.jp
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Noriko
authors.initials: N
authors.lastname: Fujiwara
authors.forename: Naokazu
authors.initials: N
authors.lastname: Takeda
authors.forename: Hiroko
authors.initials: H
authors.lastname: Minagawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000276:immunology; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000145:classification / Q000276:immunology*; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014771:Virion / Q000276:immunology; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G