title: N-vanillylnonanamide tested as a non-toxic antifoulant, applied to surfaces in a polyurethane coating.
abstract: The potential on N-vanillylnonanamide (NVN) in preventing the attachment of Pseudomonas stutzeri and a Bacillus cereus-group strain was investigated. NVN up to 852 microM was not toxic, nor was it an energy source for either organism. Microbial attachment assays were carried out on glass and polylysine slides. with NVN being dispersed in or applied to the surfaces using a polyurethane coating. NVN at 205 microM inhibited Bacillus adhesion on glass slides by 48% and the percentage did not significantly increase at 852 microM. NVN blended into or sprayed onto the coating at 205 micromol/kg did not prevent adhesion. The compound is therefore not useful as an antifouling product under the tested coating conditions.
authors.affiliation: Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, University of Milan, Via Celoria 2, 20133 Milan, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Villa
authors.forename: Lucia
authors.initials: L
authors.lastname: Giacomucci
authors.forename: Andrea
authors.initials: A
authors.lastname: Polo
authors.forename: Pamela
authors.initials: P
authors.lastname: Principi
authors.forename: Lucia
authors.initials: L
authors.lastname: Toniolo
authors.forename: Marienella
authors.initials: M
authors.lastname: Levi
authors.forename: Stefano
authors.initials: S
authors.lastname: Turri
authors.forename: Francesca
authors.initials: F
authors.lastname: Cappitelli
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects* / Q000502:physiology; D001422:Bacterial Adhesion / Q000187:drug effects*; D015169:Colony Count, Microbial; D050296:Microbial Viability; D011140:Polyurethanes; D044223:Pseudomonas stutzeri / Q000187:drug effects* / Q000502:physiology; D014641:Vanillic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D011140:Polyurethanes; C005871:vanillyl-N-nonylamide; D014641:Vanillic Acid