title: Cutaneous lymphoid hyperplasia (pseudolymphoma) in tattoos: a case series of seven patients.
abstract: BACKGROUND
  Cutaneous lymphoid hyperplasia (CLH or pseudolymphoma) is considered a rare complication occurring in tattoos. We analysed the demographics, clinical features, histological aspects, allergy tests, outcome and therapeutic data of CLH in tattoos performed by a professional in a series of patients.
  
  
  METHODS
  We conducted a retrospective chart review of seven patients managed in private practice of dermatology all over France from 2001 to 2007.
  
  
  RESULTS
  Reactions occurred within 2 years after tattooing, were non-specific (pruritus, swelling, infiltration) and mainly restricted to red. Photosensitivity was noted in two cases. Histology was characteristic of pseudolymphoma with a T-cell predominance in all cases. Surgery (2 cases) and laser removal (2 cases, CO2 and QS-532 nm) were efficient, while local corticosteroids were not. One patient had spontaneous clinical remission after 2 years of evolution.
  
  
  CONCLUSIONS
  This is the largest series of CLH occurring in tattoos. This delayed hypersensitivity reaction may be underestimated and triggered by a specific immunogenic compound of the ink. Its management remains difficult.
authors.affiliation: Department of Dermatology, University of Montpellier I, Hôpital Saint-Eloi, CHU de Montpellier, Montpellier, France. nicolaskluger@yahoo.fr
authors.forename: N
authors.initials: N
authors.lastname: Kluger
authors.forename: C
authors.initials: C
authors.lastname: Vermeulen
authors.forename: P
authors.initials: P
authors.lastname: Moguelet
authors.forename: H
authors.initials: H
authors.lastname: Cotten
authors.forename: M H
authors.initials: MH
authors.lastname: Koeb
authors.forename: B
authors.initials: B
authors.lastname: Balme
authors.forename: T
authors.initials: T
authors.lastname: Fusade
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019310:Pseudolymphoma / Q000209:etiology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000209:etiology*; D013653:Tattooing / Q000009:adverse effects*