title: Alpha-chiral acetylenes having an all-carbon quaternary center: phase transfer catalyzed enantioselective alpha alkylation of alpha-alkyl-alpha-alkynyl esters.
abstract: Going through the phases: The title reaction was found to proceed by an initial base-mediated isomerization to allenyl esters and subsequent phase transfer catalyzed alkylation at the alpha position of the ester (see scheme).
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Kazuki
authors.initials: K
authors.lastname: Sakata
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka