title: [Acute pancreatitis and space-occupying hepatic lesions in a patient with bone marrow transplant due to multiple myeloma].
abstract: Patients with multiple myeloma (MM) do not have a higher incidence of acute pancreatitis or pancreatitis of other etiologies than the general population. However, these patients may develop acute pancreatitis, or hyperamylasemia or isolated hyperlipasemia, due to etiologies that are highly infrequent in the absence of hematological disease. Liver involvement is found in 30-50% of patients with MM and mainly manifests as diffuse sinusoidal infiltration and less frequently in the form of nodules. We report the case of a patient who underwent bone marrow transplantation due to MM who showed clinical and laboratory findings compatible with acute pancreatitis of unknown origin, during which the presence of multiple space-occupying hepatic lesions was identified. Based on the results of biopsy, a diagnosis of extramedullary recurrence of MM was established.
authors.affiliation: Servicio de Digestivo, Hospital Universitario de Fuenlabrada, Madrid, España. jcarneros.hflr@salud.madrid.org
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Carneros
authors.forename: Belén
authors.initials: B
authors.lastname: Piqueras
authors.forename: Esperanza
authors.initials: E
authors.lastname: Tomás
authors.forename: Fernando
authors.initials: F
authors.lastname: García-Durán
authors.forename: Constanza
authors.initials: C
authors.lastname: Ciriza
authors.forename: Fernando
authors.initials: F
authors.lastname: Bermejo
authors.forename: Sandra
authors.initials: S
authors.lastname: Sánchez-Prudencio
authors.forename: Paz
authors.initials: P
authors.lastname: Valer
authors.forename: Iván
authors.initials: I
authors.lastname: Guerra
authors.forename: Silvia
authors.initials: S
authors.lastname: García-Garzón
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Villa
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rodríguez Agulló
mesh_terms: D000208:Acute Disease; D000328:Adult; D000681:Amylases / Q000097:blood; D016026:Bone Marrow Transplantation; D006801:Humans; D008049:Lipase / Q000097:blood; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D009101:Multiple Myeloma / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D010195:Pancreatitis / Q000097:blood / Q000209:etiology*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D014463:Ultrasonography
chemical_list: D008049:Lipase; D000681:Amylases