A synthesis of an ionomycin calcium complex.
Caught in the middle: The ionomycin calcium complex (see structure; O red, Ca green) was the target of an approach featuring the efficient asymmetric synthesis of an allene by a copper(I)-mediated anti-selective S(N)2' reaction, a highly stereoselective gold(III)-catalyzed cycloisomerization of an alpha-hydroxyallene, and a Rh-catalyzed rearrangement of an alpha-diazo-beta-hydroxyketone.
Gao
Zhanghua
Z
The School of Chemistry and The Institute of Process Research and Development, Leeds University, Leeds LS2 9 JT, UK.
Li
Yingfa
Y
Cooksey
John P
JP
Snaddon
Thomas N
TN
Schunk
Stefan
S
Viseux
Eddy M E
EM
McAteer
Stephen M
SM
Kocienski
Philip J
PJ
D000900:Anti-Bacterial Agents / Q000737:chemistry; D002118:Calcium / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry; D015759:Ionomycin / Q000737:chemistry*; D013237:Stereoisomerism
D000900:Anti-Bacterial Agents; D015759:Ionomycin; D006046:Gold; D002118:Calcium