title: Accuracy of preoperative magnetic resonance imaging in assessing lymph node metastasis and myometrial invasion in patients with uterine cancer.
abstract: OBJECTIVE
  Our aim was to know preoperative magnetic resonance imaging (MRI) can accurately predict lymph node metastasis (LNM) and deep myometrial invasion (DMI, > or = 50%) in patients with uterine cancer.
  
  
  METHODS
  From January 1997 to December 2006, 99 patients who were diagnosed with uterine cancer and surgically staged at our institution were retrospectively analyzed. Preoperative clinicopathologic characteristics and MRI findings were reviewed and compared with LNM status and DMI observed in the final pathology.
  
  
  RESULTS
  The sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) for MRI in determination of pelvic LNM were 77.7%, 85.6%, 35.0%, and 94.7%, respectively. MRI failed to detect the presence of paraaortic LNM in all of the three patients with positive paraaortic lymph nodes. The sensitivity, specificity, PPV, and NPV for MRI in determining DMI were 46.6%, 84.5%, 35%, and 89.8%, respectively.
  
  
  CONCLUSIONS
  Preoperative evaluation of uterine cancer by MRI does not accurately predict the LNM and DMI.
authors.affiliation: Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: S C
authors.initials: SC
authors.lastname: Yoo
authors.forename: W Y
authors.initials: WY
authors.lastname: Kim
authors.forename: J H
authors.initials: JH
authors.lastname: Yoon
authors.forename: H Y
authors.initials: HY
authors.lastname: Kim
authors.forename: E J
authors.initials: EJ
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Chang
authors.forename: K H
authors.initials: KH
authors.lastname: Chang
authors.forename: H S
authors.initials: HS
authors.lastname: Ryu
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology*; D009361:Neoplasm Invasiveness; D010388:Pelvis; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery