title: Nasal reconstruction of the leprosy nose using costal cartilage.
abstract: Leprosy is a chronic granulomatous infection of the skin and peripheral nerves that often leads to gross deformation of the nasal skeleton and subsequent formation of a saddle-nose deformity. Reconstruction of the nose following Mycobacterium leprae infection has challenged surgeons for centuries. As a result, a number of different techniques have been attempted with varying outcomes. This article describes the case and surgical treatment of a 37-year old female who presented with a subtotal nasoseptal perforation and saddle-nose deformity secondary to previous infection with leprosy. Reconstruction was achieved via an open septorhinoplasty approach using autologous costal cartilage grafts, yielding a successful postoperative result.
authors.affiliation: Division of Facial Plastic Surgery, Section of Otolaryngology, University of Chicago, 845 North Michican Avenue, Suite 934e, Chicago, IL 60611, USA.
authors.forename: Anil R
authors.initials: AR
authors.lastname: Shah
authors.forename: Daniel
authors.initials: D
authors.lastname: Zeitler
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Wise
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D007918:Leprosy / Q000150:complications* / Q000188:drug therapy; D055171:Nasal Cartilages / Q000473:pathology / Q000637:transplantation*; D015508:Nasal Obstruction / Q000209:etiology / Q000601:surgery; D009300:Nasal Septum / Q000473:pathology / Q000601:surgery; D009667:Nose Deformities, Acquired / Q000209:etiology / Q000601:surgery*; D012225:Rhinoplasty; D012272:Ribs; D014182:Transplantation, Autologous
chemical_list: D007917:Leprostatic Agents