Comparison of three methods of testing hearing in mice.
BACKGROUND
This study compares the reliability and validity of three methods of testing hearing in mice.


METHODS
Animal research laboratory.


METHODS
Three methods of testing hearing were used in 18 mice: (1) auditory brainstem response (ABR), (2) electrocochleography with a needle electrode, and (3) electrocochleography with a soft, cotton-wick electrode.


RESULTS
Reliability was good for all three tests, but ABR testing was the easiest and provided the lowest thresholds and least variability. The results for these tests under other conditions may vary.


CONCLUSIONS
ABR testing can be considered an optimal test method under the circumstances in this study.
Quddusi
Taeed
T
Department of Otolaryngology,University of Manitoba, Winnipeg, Manitoba, Canada
Blakley
Brian W
BW
D000818:Animals; D001300:Audiometry, Evoked Response / Q000379:methods; D016057:Evoked Potentials, Auditory, Brain Stem; D051379:Mice; D008810:Mice, Inbred C57BL; D015203:Reproducibility of Results