[Risk factors for respiratory morbidity at 12 to 36 months in very low birth weight premature infants previously admitted to a public neonatal intensive care unit].
The aim of this paper was to estimate respiratory morbidity and its determinants for premature infants aged 12 to 36 months. The population comprised 84 infants from a cohort of very low birth weight premature infants. The outcome was the respiratory morbidity incidence rate. The relationship between the independent variables and respiratory morbidity was estimated using a Poisson regression model. From 12 to 24 months of age, 56.3% of children had experienced at least one episode of respiratory disease. >From 24 to 36 months, 38.1% of children were affected. Variables significantly associated with respiratory morbidity were bronchopulmonary dysplasia (RR = 1.9; 95%CI: 1.2-2.9), abnormal lung compliance (RR = 1.6; 95%CI: 1.1-2.3), neonatal pneumonia (RR = 2.8; 95%CI: 1.9-4.0), patent ductus arteriosus (RR = 1.6; 95%CI: 1.1-2.5), and respiratory morbidity in the first year of life (RR = 1.7; 95%CI: 1.2-2.5). The incidence of respiratory morbidity remains high in this group of high-risk infants, which calls for regular follow-up and effective interventions to prevent respiratory disease and to improve the quality of life of these children and their families.
Chalfun
Geórgia
G
Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Mello
Rosane Reis de
RR
Dutra
Maria Virginia Peixoto
MV
Andreozzi
Valeska Lima
VL
Silva
Kátia Silveira da
KS
D001938:Brazil / Q000453:epidemiology; D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology* / Q000517:prevention & control; D019102:Infant, Very Low Birth Weight; D008297:Male; D009017:Morbidity; D011014:Pneumonia / Q000453:epidemiology; D012135:Respiratory Sounds; D012140:Respiratory Tract Diseases / Q000453:epidemiology* / Q000517:prevention & control; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factors