Buprenorphine for opioid dependence.
Buprenorphine is a partial mu agonist opioid that is FDA-approved to manage opioid addiction in settings outside of traditional methadone clinics. The clinical uses, pharmacokinetics, pharmacodynamics, toxicology, and management of overdoses of buprenorphine are reviewed.
Milne
Megan
M
College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Crouch
Barbara Insley
BI
Caravati
E Martin
EM
D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use; D002047:Buprenorphine / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D062787:Drug Overdose / Q000188:drug therapy; D006801:Humans; D009292:Narcotic Antagonists / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D010146:Pain / Q000188:drug therapy
D000701:Analgesics, Opioid; D009292:Narcotic Antagonists; D002047:Buprenorphine