title: Smoothening the controversial role of hedgehog in hematopoiesis.
abstract: The role of multiple developmental signaling pathways in the regulation of hematopoiesis has been controversial. In this issue of Cell Stem Cell, two separate reports (Hofmann et al., 2009; Gao et al., 2009) examine whether the Hedgehog signaling pathway modulates normal adult hematopoietic stem cells and blood formation.
authors.affiliation: Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, Baltimore, MD 21231, USA.
authors.forename: Akil A
authors.initials: AA
authors.lastname: Merchant
authors.forename: William
authors.initials: W
authors.lastname: Matsui
mesh_terms: D001773:Blood Cells / Q000166:cytology; D053823:Hedgehog Proteins / Q000502:physiology*; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans; D015398:Signal Transduction
chemical_list: D053823:Hedgehog Proteins