title: Reduction of the total injection volume of contrast material with a short injection duration in 64-detector row CT coronary angiography.
abstract: The ability of short injection duration of contrast material to reduce the total injection volume in 64-detector row CT coronary angiography was investigated. 45 patients were divided into three groups: (i) those receiving 0.8 ml kg(-1) of contrast material (350 mgI ml(-1)) injected with a fixed duration of 14 s (Group A; n = 16); (ii) those receiving 0.8 ml kg(-1) of contrast material injected with a fixed duration of 10 s (Group B; n = 15); and (iii) those receiving 0.7 ml kg(-1) of contrast material injected with a fixed duration of 10 s (Group C; n = 14). All patients then received 20 ml of saline. Contrast densities of the ascending aorta and proximal and distal coronary arteries were assessed where vessel diameters were >2.0 mm. The mean enhancement value in the ascending aorta for Group B was significantly higher than that for Groups A and C (p<0.05), whereas there was no significant difference between Groups A and C. All enhancement values in the coronary arteries were higher than 250 Hounsfield units. The mean enhancement value for each coronary artery in Group B was significantly higher than that for Group A (p<0.05), whereas there was no significant difference between Groups A and C. In conclusion, a short injection duration allows a reduction in the total volume of contrast material from 0.8 ml kg(-1) to 0.7 ml kg(-1) while a steady contrast enhancement is maintained in the ascending aorta and coronary arteries.
authors.affiliation: Department of Radiology, Osaka Medical College,Takatsuki City, Osaka 569-8686, Japan. sa104@rg8.so-net.ne.jp
authors.forename: F
authors.initials: F
authors.lastname: Tatsugami
authors.forename: T
authors.initials: T
authors.lastname: Kanamoto
authors.forename: G
authors.initials: G
authors.lastname: Nakai
authors.forename: Y
authors.initials: Y
authors.lastname: Takeda
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: I
authors.initials: I
authors.lastname: Morinaga
authors.forename: S
authors.initials: S
authors.lastname: Yoshikawa
authors.forename: I
authors.initials: I
authors.lastname: Narabayashi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001027:Aortography; D001835:Body Weight; D003287:Contrast Media / Q000008:administration & dosage*; D017023:Coronary Angiography / Q000379:methods* / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007479:Iopamidol / Q000008:administration & dosage / Q000031:analogs & derivatives*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011856:Radiographic Image Enhancement / Q000379:methods; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media; C057937:iomeprol; D012965:Sodium Chloride; D007479:Iopamidol