title: Percutaneous transcatheter aortic valve replacement: first transfemoral implant in Asia.
abstract: Surgical aortic valve replacement (AVR) is the standard of care for patients with symptomatic severe aortic stenosis (AS), providing relief of symptoms and prolonging survival. However, many patients are either denied or not offered surgery due to high surgical risk or non-operability for open AVR. The technology of percutaneous aortic valve implantation emerged in 2002, and has since evolved rapidly with satisfactory results. Currently, almost all the procedures are performed predominantly in Europe and North America. The first-in-Asia percutaneous transcatheter aortic valve implantation via the transfemoral route is described. A 77-year-old man with symptomatic severe AS and at high surgical risk was successfully treated, with sustained clinical improvement and satisfactory haemodynamic results at 30-day follow-up.
authors.affiliation: Department of Cardiology, National Heart Centre, 17 Third Hospital Avenue, Singapore. paul.chiam.t.l@nhc.com.sg
authors.forename: P T
authors.initials: PT
authors.lastname: Chiam
authors.forename: T H
authors.initials: TH
authors.lastname: Koh
authors.forename: V T
authors.initials: VT
authors.lastname: Chao
authors.forename: C Y
authors.initials: CY
authors.lastname: Lee
authors.forename: V Y
authors.initials: VY
authors.lastname: See Tho
authors.forename: S Y
authors.initials: SY
authors.lastname: Tan
authors.forename: S T
authors.initials: ST
authors.lastname: Lim
authors.forename: N C
authors.initials: NC
authors.lastname: Hwang
authors.forename: Y K
authors.initials: YK
authors.lastname: Sin
authors.forename: Y L
authors.initials: YL
authors.lastname: Chua
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery / Q000628:therapy*; D001208:Asia; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D011474:Prosthesis Design