Normal pressure hydrocephalus.
Normal Pressure Hydrocephalus first became recognized as a treatable, reversible disorder in the 1960s. The classic triad of magnetic apraxia, urinary incontinence, and dementia remain relevant into the 21(st) century as being the basis for symptomatic diagnosis and predicting potential benefit from ventriculoperitoneal shunting, though they have been greatly augmented by the addition of modern neuroimaging, particularly MRI. Modern criteria recognize a wider range of diagnostic criteria, and new positive and negative prognostic indicators for treatment benefit have been discovered, though the mainstay remains initial drainage of a large volume of cerebrospinal fluid and monitoring for clinical improvement. Even with our advances in understanding both primary and secondary normal pressure hydrocephalus, diagnosis, management, and counseling remain challenging in this disorder.
Finney
Glen R
GR
Memory and Cognitive Disorders Program, University of Florida Department of Neurology, Gainesville, Florida 32610-0236, USA.
D002557:Cerebrospinal Fluid Shunts / Q000379:methods; D003952:Diagnostic Imaging / Q000379:methods; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000175:diagnosis / Q000266:history / Q000628:therapy