title: Antibiotics as intracanal medicaments: a review.
abstract: Antibiotics are an extremely valuable addition to the armamentarium available to health practitioners for management of bacterial infections. Due to the potential risk of adverse systemic effects of systemic applications and ineffectiveness of systemic antibiotics in the necrotic pulpless tooth and the periradicular tissues, local application of antibiotics may be a more effective mode for delivering antibiotics to infected root canals. This paper reviews the history, rationale, and applications of antibiotics and antibiotics-containing medicaments in endodontics.
authors.affiliation: Department of Endodontics, Sadoughi University of Medical Sciences, Yazd, Iran. mohammadi_zahed@yahoo.com
authors.forename: Zahed
authors.initials: Z
authors.lastname: Mohammadi
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D000891:Anti-Infective Agents, Local; D001420:Bacteria, Aerobic / Q000187:drug effects; D001421:Bacteria, Anaerobic / Q000187:drug effects; D003790:Dental Pulp Necrosis / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000209:etiology; D005334:Fever / Q000139:chemically induced; D005898:Glass; D006801:Humans; D010485:Periapical Periodontitis / Q000188:drug therapy; D012388:Root Canal Irrigants
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D012388:Root Canal Irrigants; C403922:bioactive glass S53P4