title: Cholinergic denervation occurs early in Parkinson disease.
authors.forename: Nicolaas I
authors.initials: NI
authors.lastname: Bohnen
authors.forename: Roger L
authors.initials: RL
authors.lastname: Albin
mesh_terms: D000109:Acetylcholine / Q000172:deficiency*; D020532:Basal Nucleus of Meynert / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D002799:Cholinergic Fibers / Q000378:metabolism / Q000473:pathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D016631:Lewy Bodies / Q000378:metabolism / Q000473:pathology; D020961:Lewy Body Disease / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D009069:Movement Disorders / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D009410:Nerve Degeneration / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D009434:Neural Pathways / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D010300:Parkinson Disease / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D010641:Phenotype; D058225:Plaque, Amyloid / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography; D013997:Time Factors
chemical_list: D000109:Acetylcholine