title: [Hypertension and the brain].
abstract: Hypertension is a major and modifiable risk factor of stroke and dementia. Hypertension causes remodelling of the cerebral resistance vessels, impairing their tolerance to very low blood pressure. In primary prevention of stroke, the effect of beta-blockers is inferior to other classes of antihypertensives. In secondary prevention of stroke, ACE-inhibitors and angiotensin blockers may be recommended as first choice drugs. Lowering of the blood pressure is, however, more important than the choice of drug.
authors.affiliation: Neurologisk Afdeling N, Bispebjerg Hospital, DK-2400 København NV. hc04@bbh.regionh.dk
authors.forename: Hanne
authors.initials: H
authors.lastname: Christensen
authors.forename: Svend
authors.initials: S
authors.lastname: Strandgaard
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D003704:Dementia / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D012307:Risk Factors; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D000959:Antihypertensive Agents