[Genetics and hypertension].
Monogenic forms of hypertension are very rare, but have a well-characterized heredity. Primary hypertension is very common with a complex and polygenic heredity. Primary hypertension arises due to an interaction between multiple genetic and environmental factors. Its heredity is unknown, although some candidate genes have been suggested. Intense research is ongoing and includes the use of modern genetics methods as genome wide association and linkage studies.
Ellervik
Christina
C
Medicinsk Forskning og Medicinsk Afdeling, Regionshospitalet Holstebro, DK-7500 Holstebro.
Tarnow
Lise
L
Pedersen
Erling Bjerregaard
EB
D000959:Antihypertensive Agents / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D055106:Genome-Wide Association Study; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000235:genetics* / Q000628:therapy; D008019:Life Style; D010597:Pharmacogenetics
D000959:Antihypertensive Agents