Heart rate variability in outbred white rats upon periodical alpha-tocopherol administration.
Effect of alpha-tocopherol (vitamin E) periodical administration on heart rhythm regulation was investigated in outbred white rats. alpha-Tocopherol administration to males was followed by reduction of sympathetic neural influence on heart rhythm and also by the increase of the number of individuals with high activity of autonomic regulation loop. In female rats alpha-tocopherol administration modulates the activity of humoral control circuit and promotes heart rate reduction, however upon that the percent of females with high centralization of heart rate regulation was increased.
Kuryanova
E V
EV
Department of animal and human Physiology, Astrakhan State University, Russia. fyzevk@rambler.ru
D000818:Animals; D021461:Animals, Outbred Strains; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D051381:Rats; D024502:alpha-Tocopherol / Q000008:administration & dosage / Q000494:pharmacology*
D000975:Antioxidants; D024502:alpha-Tocopherol