title: Consensus on the appropriate use of intrathecal baclofen (ITB) therapy in paediatric spasticity.
abstract: Among features of motor disorders in children, spasticity is associated with considerable morbidity and problems in care, particularly in severely affected patients. Intrathecal baclofen (ITB) has been increasingly used as a relatively specific treatment modality for spasticity. To date, most of the evidence for its use in paediatric patients has come from retrospective and uncontrolled studies, although randomised, controlled trials of screening ITB and ITB therapy itself have recently been published. This consensus statement on the use of ITB in paediatric patients with spasticity was developed on the basis of currently available evidence, with the aim of providing information for clinicians, promoting an expert opinion and a consistent approach to the management of these patients and emphasising the need for further prospective, large-scale studies.
authors.affiliation: Department of Neurology, Hôpital Universitaire des Enfants Reine Fabiola, Université libre de Bruxelles, 15 Avenue JJ Crocq, 1020 Brussels, Belgium. bernard.dan@ulb.ac.be
authors.forename: Bernard
authors.initials: B
authors.lastname: Dan
authors.forename: Francesco
authors.initials: F
authors.lastname: Motta
authors.forename: Johann S H
authors.initials: JS
authors.lastname: Vles
authors.forename: Michael
authors.initials: M
authors.lastname: Vloeberghs
authors.forename: Jules G
authors.initials: JG
authors.lastname: Becher
authors.forename: Paul
authors.initials: P
authors.lastname: Eunson
authors.forename: Vincent
authors.initials: V
authors.lastname: Gautheron
authors.forename: Sonnhild
authors.initials: S
authors.lastname: Lütjen
authors.forename: Volker
authors.initials: V
authors.lastname: Mall
authors.forename: Samuel Ignacio
authors.initials: SI
authors.lastname: Pascual-Pascual
authors.forename: Petra
authors.initials: P
authors.lastname: Pauwels
authors.forename: Geir Ketil
authors.initials: GK
authors.lastname: Røste
mesh_terms: D001418:Baclofen / Q000627:therapeutic use*; D032921:Consensus; D017408:Guidelines as Topic; D006801:Humans; D007278:Injections, Spinal / Q000379:methods; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009128:Muscle Spasticity / Q000188:drug therapy*; D010372:Pediatrics
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen