title: Specific skin lesions in hairy cell leukemia at presentation: case report and review of literature.
abstract: Skin involvement in hairy cell leukemia (HCL) at presentation is a relatively rare manifestation of the disease. A 60-year-old male patient in whom cutaneous lesions were the initial manifestation of hairy cell leukemia together with leukocytosis, monocytopenia, massive splenomegaly, and leukemic maculopapulous infiltration of the almost whole skin is described. The present case is the forth mentioned in the literature with specify of leukocytosis in peripheral blood, consisting mostly of hairy cells. The patient was treated with two courses of 2-chlorodeoxiadenosine (2-CdA, Cladribine) and splenectomy and after this cutaneous lesion disappeared and general condition is improved.
authors.affiliation: Institute of Haematology, Clinical Center Serbia, Koste Todorovića 2, Belgrade, Serbia.
authors.forename: N
authors.initials: N
authors.lastname: Colović
authors.forename: M
authors.initials: M
authors.lastname: Perunicić
authors.forename: V
authors.initials: V
authors.lastname: Jurisić
authors.forename: M
authors.initials: M
authors.lastname: Colović
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy