Recent trends in the advanced analysis of bioactive fatty acids.
The consumption of dietary fats have been long associated to chronic diseases such as obesity, diabetes, cancer, arthritis, asthma, and cardiovascular disease; although some controversy still exists in the role of dietary fats in human health, certain fats have demonstrated their positive effect in the modulation of abnormal fatty acid and eicosanoid metabolism, both of them associated to chronic diseases. Among the different fats, some fatty acids can be used as functional ingredients such as alpha-linolenic acid (ALA), arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), gamma-linolenic acid (GLA), stearidonic acid (STA) and conjugated linoleic acid (CLA), among others. The present review is focused on recent developments in FAs analysis, covering sample preparation methods such as extraction, fractionation and derivatization as well as new advances in chromatographic methods such as GC and HPLC. Special attention is paid to trans fatty acids due its increasing interest for the food industry.
Ruiz-Rodriguez
Alejandro
A
Departamento de Caracterización de Alimentos, Instituto de Fermentaciones Industriales, CSIC, Juan de la Cierva, 3, E-28006 Madrid, Spain.
Reglero
Guillermo
G
Ibañez
Elena
E
D000818:Animals; D002849:Chromatography, Gas / Q000639:trends*; D002851:Chromatography, High Pressure Liquid / Q000639:trends*; D004281:Docosahexaenoic Acids / Q000032:analysis; D015118:Eicosapentaenoic Acid / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis* / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000032:analysis; D006801:Humans; D044242:Trans Fatty Acids / Q000032:analysis; D017962:alpha-Linolenic Acid / Q000032:analysis / Q000378:metabolism; D017965:gamma-Linolenic Acid / Q000032:analysis / Q000378:metabolism
D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D044242:Trans Fatty Acids; D017962:alpha-Linolenic Acid; D004281:Docosahexaenoic Acids; D017965:gamma-Linolenic Acid; D015118:Eicosapentaenoic Acid; C062895:stearidonic acid