title: Genotoxicity evaluation of hospital wastewaters.
abstract: In hospitals a large variety of substances are in use for medical purposes such as diagnostics and research. After application, diagnostic agents, disinfectants and excreted non-metabolized pharmaceuticals by patients reach the wastewater. Indeed, some of the substances found in wastewaters are genotoxic and are suspected to be a possible cause of the cancers observed in the last decades. Genotoxicity tests are an excellent means to study the toxicity and the risk associated with these releases. This paper points out the areas of concern for hospital wastewater disposal and reports the findings of genotoxicity tests for hospital effluents from 3 major hospitals in Delhi, namely All India Institute of Medical Sciences, Apollo and Escorts. Mutagenicity of hospital wastewaters from effluent treatment plants (before and after treatment) was studied. The results of this study show that the genotoxicity of hospital wastewaters is highly reduced after the treatment process. This study calls for establishment of advanced and effective effluent treatment plants in the hospitals, which are merely dumping the wastewaters in the municipal sewerage system. The results of this study call for further detailed study in this area.
authors.affiliation: Environmental Toxicology Unit, Department of Zoology, University of Rajasthan, Jaipur 302004, India. p_gupta2000@hotmail.com
authors.forename: Preeti
authors.initials: P
authors.lastname: Gupta
authors.forename: N
authors.initials: N
authors.lastname: Mathur
authors.forename: P
authors.initials: P
authors.lastname: Bhatnagar
authors.forename: P
authors.initials: P
authors.lastname: Nagar
authors.forename: S
authors.initials: S
authors.lastname: Srivastava
mesh_terms: D004305:Dose-Response Relationship, Drug; D004784:Environmental Monitoring; D006256:Hazardous Waste; D006761:Hospitals / Q000592:standards; D007194:India; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D006256:Hazardous Waste; D009153:Mutagens; D014874:Water Pollutants, Chemical