Recovery of function in humans: cortical stimulation and pharmacological treatments after stroke.
In this contribution, we first provide an overview of general principles of reorganisation in the human brain, and point out possible biomarkers of recovery. Subsequently, we expand on possibilities of adjuvant therapy in human rehabilitation using cortical stimulation and pharmacological treatments. Finally, we suggest future directions for research in this field.
Floel
Agnes
A
Department of Neurology, University of Muenster, Germany. floeel@uni-muenster.de
Cohen
Leonardo G
LG
D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D002540:Cerebral Cortex / Q000187:drug effects* / Q000503:physiopathology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D018491:Dopamine Agonists / Q000494:pharmacology / Q000627:therapeutic use; D004599:Electric Stimulation Therapy / Q000379:methods* / Q000639:trends; D006801:Humans; D009414:Nerve Growth Factors / Q000494:pharmacology* / Q000627:therapeutic use; D017063:Outcome Assessment, Health Care / Q000379:methods; D020127:Recovery of Function / Q000187:drug effects* / Q000502:physiology; D020521:Stroke / Q000628:therapy*; D050781:Transcranial Magnetic Stimulation / Q000379:methods / Q000639:trends
D015415:Biomarkers; D002800:Cholinesterase Inhibitors; D018491:Dopamine Agonists; D009414:Nerve Growth Factors