title: [The role of cervical mediastinoscopy and video assisted thoracoscopy in the diagnosis and staging of thoraco-mediastinal neoplastic diseases].
abstract: BACKGROUND
  In this work we evaluate the role of mediastinoscopy and video-assisted thoracoscopy in the diagnosis and staging of coin lesion of the lung and of mediastinal masses.
  
  
  METHODS
  72 patients, 55 males and 17 females, affected by lung coin lesion without any previous histological diagnosis have been admitted to our Institution from 1997 to 2007. Mean age was 59.4 for males (range 29-82) and 57.2 for females (range 14-79).
  
  
  RESULTS
  Mediastinoscopy resulted to be diagnostic in 95% of cases. In just one case mediastinoscopy failed and video assisted thoracoscopy was performed, which permitted to obtain diagnosis. Video assisted thoracoscopy was able to lead to diagnosis in 98.1% of cases, as we observed only one failure. In this single case we converted the thoracoscopic approach to open, but although the conversion it was not possible to make diagnosis.
  
  
  CONCLUSIONS
  In these ten years, thanks to adequate indication for mediastinoscopy and video assisted thoracoscopy, the use of thoracotomy for diagnosis and staging of pulmonary neoplastic diseases has been reduced: thus we avoided 80% of unnecessary thoracotomies in patients affected by not resectable lung cancer, metastases (treated by atypical thoracoscopic resection) or benign diseases.
  
  
  CONCLUSIONS
  The minimally invasive surgical exploration of mediastinum and thoracic cavity allows to obtain all necessary informations (in terms of histology and staging) to programme an adequate therapeutic protocol, reducing postoperative pain and hospital stay, in comparison to thoracotomy.
authors.affiliation: Istituto di Patologia Chirurgica, Università degli Studi di Sassari, Italy. f.attene@uniss.it
authors.forename: Federico
authors.initials: F
authors.lastname: Attene
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Scognamillo
authors.forename: Andreas
authors.initials: A
authors.lastname: Xidas
authors.forename: Fernando
authors.initials: F
authors.lastname: Serventi
authors.forename: Mario
authors.initials: M
authors.lastname: Trignano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008481:Mediastinoscopy / Q000379:methods; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy; D011379:Prognosis; D012189:Retrospective Studies; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods; D016896:Treatment Outcome