title: Urinary 1-hydroxypyrene levels in offshore workers.
abstract: OBJECTIVE
  To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group.
  
  
  METHODS
  Participants' (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models.
  
  
  RESULTS
  (1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels.
  
  
  CONCLUSIONS
  Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.
authors.affiliation: University of Cincinnati, Cincinnati, OH, USA. NancyBHopf@gmail.com
authors.forename: Nancy Brenna
authors.initials: NB
authors.lastname: Hopf
authors.forename: Jorunn
authors.initials: J
authors.lastname: Kirkeleit
authors.forename: Stacy L
authors.initials: SL
authors.lastname: Kramer
authors.forename: Bente
authors.initials: B
authors.lastname: Moen
authors.forename: Paul
authors.initials: P
authors.lastname: Succop
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Genter
authors.forename: Tania
authors.initials: T
authors.lastname: Carreón
authors.forename: James
authors.initials: J
authors.lastname: Mack
authors.forename: Glenn
authors.initials: G
authors.lastname: Talaska
mesh_terms: D000328:Adult; D002851:Chromatography, High Pressure Liquid; D019652:Extraction and Processing Industry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*; D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis; D011721:Pyrenes / Q000032:analysis*
chemical_list: D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons; D011721:Pyrenes; C033146:1-hydroxypyrene