title: Implementation of the NCRP wound model for interpretation of bioassay data for intake of radionuclides through contaminated wounds.
abstract: Emergency response preparedness for radiological accidents involving wound contamination has become more important, considering the current extending tendency in the nuclear industry related to the nuclear fuel cycle. The US National Council on Radiation Protection and Measurements (NCRP) proposed a biokinetic and dosimetric model for the intake of radionuclides through contaminated wounds in 2007. The present paper describes the implementation of this NCRP wound model for the prediction of systemic behaviour of some important radioactive elements encountered in workplaces related to the nuclear industry. The NCRP wound model was linked to the current ICRP systemic model at each blood compartment and simultaneous differential equations for the content of radioactivity in each compartment and excreta were solved with the Runge-Kutta method. The results of the calculation of wound, whole-body or specific organ retention and daily urinary or faecal excretion rate of some selected elements will be useful for the interpretation of bioassay data and dose assessment for cases of wound contamination.
authors.affiliation: Department of Health Sciences, School of Medicine, Nagoya University, 1-1-20 Daiko-minami, Higashi-ku, Nagoya, Japan. ishigure@met.nagoya-u.ac.jp
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Ishigure
mesh_terms: D000818:Animals; D001681:Biological Assay; D003198:Computer Simulation; D011868:Radioisotopes / Q000493:pharmacokinetics*; D014946:Wound Infection
chemical_list: D011868:Radioisotopes