Incidence and clinical predictors of deep vein thrombosis in patients hospitalized with heart failure in Japan.
BACKGROUND
The aim of this study was to clarify the incidence and clinical predictors of deep vein thrombosis (DVT) in patients with congestive heart failure (CHF) in Japan.


RESULTS
Between January 2003 and January 2008, 161 patients were admitted to Mie University Hospital with a diagnosis of CHF and underwent venous compression ultrasonography. Of them, 18 patients (11.2%) were diagnosed with DVT. As defined by New York Heart Association (NYHA) functional class, class IV patients had a higher incidence rate of DVT than those in class II or III (class II: 3 patients (4.4%), class III: 2 patients (4.8%), class IV: 13 patients (25.5%), P<0.01). Multiple logistic regression analysis identified that NYHA functional class and poor collapsibility of the inferior vena cava on ultrasonography as independent predictors of DVT (odds ratios (OR) 3.74, 95% confidence interval (CI) 1.72-8.16, P<0.01 and OR 4.43, 95%CI 1.36-14.43, P<0.05, respectively). Therapy without anticoagulation also indicated a significant increase in DVT incidence in CHF patients (OR 3.71, 95%CI 1.13-12.18, P<0.05).


CONCLUSIONS
Patients with CHF have a high risk for DVT and the risk increases according to NYHA functional class, poor IVC collapsibility or therapy without anticoagulation.
Ota
Satoshi
S
Department of Cardiology, Mie University Graduate School of Medicine, Tsu, Japan.
Yamada
Norikazu
N
Tsuji
Akihiro
A
Ishikura
Ken
K
Nakamura
Mashio
M
Ito
Masaaki
M
D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000453:epidemiology; D006334:Heart Function Tests; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007564:Japan; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D014463:Ultrasonography; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology*