title: Study of efficiency of therapeutic and preventive anaferon (pediatric formulation) in mice with influenza infection.
abstract: Therapeutic and preventive treatment of mice intranasally infected with a lethal dose of A/Aichi/2/68 (H3N2) influenza virus with anaferon (pediatric formulation) demonstrated an antiviral effect of the drug (increased percent of survivors and prolonged lifespan).
authors.affiliation: Vector Center of Virology and Biotechnology, Koltsovo, Novosibirsk Region, Russia.
authors.forename: L N
authors.initials: LN
authors.lastname: Shishkina
authors.forename: A N
authors.initials: AN
authors.lastname: Sergeev
authors.forename: A S
authors.initials: AS
authors.lastname: Kabanov
authors.forename: M O
authors.initials: MO
authors.lastname: Skarnovich
authors.forename: N K
authors.initials: NK
authors.lastname: Evtin
authors.forename: N A
authors.initials: NA
authors.lastname: Mazurkova
authors.forename: A A
authors.initials: AA
authors.lastname: Sergeev
authors.forename: M V
authors.initials: MV
authors.lastname: Belopolskaya
authors.forename: I A
authors.initials: IA
authors.lastname: Kheyfets
authors.forename: J L
authors.initials: JL
authors.lastname: Dugina
authors.forename: S A
authors.initials: SA
authors.lastname: Tarasov
authors.forename: S A
authors.initials: SA
authors.lastname: Sergeeva
authors.forename: O I
authors.initials: OI
authors.lastname: Epstein
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects / Q000472:pathogenicity; D007371:Interferon-gamma / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009976:Orthomyxoviridae Infections / Q000188:drug therapy* / Q000276:immunology / Q000401:mortality; D053139:Oseltamivir / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir; D007371:Interferon-gamma