title: Emergence of extended-spectrum beta-lactamase-producing Escherichia coli in community hospitals throughout North Carolina: a harbinger of a wider problem in the United States?
abstract: Community-onset urinary tract infections due to extended-spectrum beta-lactamase-producing Escherichia coli have become increasingly common worldwide but have been considered to be uncommon infections in the United States. We report the emergence and subsequent rapid increase in the incidence of these infections in community hospitals throughout North Carolina since 2006.
authors.affiliation: Duke Infection Control Outreach Network, Duke University Medical Center, Durham, North Carolina 27710, USA. Joshua.freeman@duke.edu
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Freeman
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Sexton
authors.forename: Deverick J
authors.initials: DJ
authors.lastname: Anderson
mesh_terms: D000328:Adult; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D004926:Escherichia coli / Q000201:enzymology* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000096:biosynthesis*; D006764:Hospitals, Community; D006801:Humans; D015994:Incidence; D009657:North Carolina / Q000453:epidemiology; D014571:Urologic Neoplasms / Q000453:epidemiology / Q000382:microbiology; D055815:Young Adult; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D029968:Escherichia coli Proteins; D001618:beta-Lactamases