Comparative analysis of the spindle and chromosome configurations of in vitro-matured oocytes from patients with endometriosis and from control subjects: a pilot study.
Preliminary data from a prospective controlled study did not demonstrate an increased percentage of meiotic abnormalities for in vitro-matured oocytes obtained from stimulated cycles of endometriosis and control patients. However, the tendency toward a higher proportion of telophase I in apparently matured oocytes observed in endometriosis patients suggests an impairment or delay of the completion of meiosis I which requires further evaluation.
Barcelos
Ionara D
ID
Department of Obstetrics and Gynecology, Ribeirão Preto Medical School, São Paulo University, Ribeirão Preto, São Paulo, Brazil.
Vieira
Rodolpho C
RC
Ferreira
Elisa M
EM
Martins
Wellington P
WP
Ferriani
Rui A
RA
Navarro
Paula A
PA
D000328:Adult; D016022:Case-Control Studies; D002478:Cells, Cultured; D002877:Chromosomes, Human / Q000737:chemistry / Q000378:metabolism; D020732:Cytogenetic Analysis; D004715:Endometriosis / Q000150:complications / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000235:genetics / Q000473:pathology; D008297:Male; D009865:Oocytes / Q000378:metabolism / Q000473:pathology / Q000502:physiology*; D009866:Oogenesis / Q000235:genetics; D010049:Ovarian Diseases / Q000150:complications / Q000235:genetics* / Q000473:pathology; D010312:Parthenogenesis / Q000235:genetics / Q000502:physiology; D010865:Pilot Projects; D011786:Quality Control; D008941:Spindle Apparatus / Q000235:genetics / Q000378:metabolism / Q000473:pathology*