Morphological changes in bird viscera in experimental infection by highly pathogenic H5N1 avian influenza virus.
Intravenous infection of chicken with H5N1 avian influenza virus (strain A/Gs/Krasnoozerskoye/627/05) causes rapid lethal outcome. Pathomorphological study of bird viscera showed manifestations of disseminated intravascular coagulation syndrome, generalized inflammatory reaction, and wide-scale necrobiotic changes in tissues.
Shestopalova
L V
LV
Department of Physiology, Novosibirsk State University, Novosibirsk Region, Koltsovo, Russia. lv@fen.nsu.ru
Shkurupiy
V A
VA
Sharkova
T V
TV
Shestopalov
A M
AM
D000818:Animals; D001921:Brain / Q000473:pathology / Q000821:virology; D002642:Chick Embryo; D002645:Chickens; D053124:Influenza A Virus, H5N1 Subtype / Q000472:pathogenicity*; D005585:Influenza in Birds / Q000473:pathology* / Q000821:virology*; D007668:Kidney / Q000473:pathology / Q000821:virology; D008168:Lung / Q000473:pathology / Q000821:virology; D013154:Spleen / Q000473:pathology / Q000821:virology; D014781:Viscera / Q000473:pathology* / Q000821:virology*