title: Magnetic resonance-guided biopsy of the prostate: feasibility, technique, and clinical applications.
abstract: OBJECTIVE
  To describe the technique of magnetic resonance (MR)-guided biopsy as performed in our institution and highlight trends from current literature.
  
  
  METHODS
  Local protocols for MR prostate cancer localization and its image data analysis are described. Acquisition of a 3-dimensional localization for a tumor suspected region and its reidentification on a second MR-guided biopsy session are explained. Furthermore, detailed information about the procedure, the biopsy technique itself, and the current trends are discussed and highlighted.
  
  
  RESULTS
  Magnetic resonance-guided biopsies have a higher tumor detection rate of prostate cancer in patients with clinical suspicion of prostate cancer and repeated negative transrectal ultrasound-guided biopsies. It is a feasible and accurate technique.
  
  
  CONCLUSIONS
  Performance of MR-guided prostate biopsies, using suggested techniques, protocols, and equipment, is a feasible and accurate technique. It has been proven to be an accurate method for the detection of significant prostate cancer in men with repetitive previous negative biopsies.
authors.affiliation: Department of Radiology, Radboud University, Nijmegen Medical Centre, Geert Grooteplein zuid, Nijmegen, the Netherlands. D.Yakar@rad.umcn.nl
authors.forename: Derya
authors.initials: D
authors.lastname: Yakar
authors.forename: Thomas
authors.initials: T
authors.lastname: Hambrock
authors.forename: Caroline
authors.initials: C
authors.lastname: Hoeks
authors.forename: Jelle O
authors.initials: JO
authors.lastname: Barentsz
authors.forename: Jurgen J
authors.initials: JJ
authors.lastname: Fütterer
mesh_terms: D000368:Aged; D001706:Biopsy / Q000295:instrumentation*; D003287:Contrast Media / Q000008:administration & dosage; D038524:Diffusion Magnetic Resonance Imaging; D005240:Feasibility Studies; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000008:administration & dosage; D009942:Organometallic Compounds / Q000008:administration & dosage; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D008536:Meglumine; C072417:gadoterate meglumine