title: Hypercoagulability in a patient with chronic chyluria, proteinuria and hypoalbuminaemia.
abstract: We describe the case of a young man with prolonged and severe chyluria from a previous parasitic infection. He presented with an acute myocardial infarction most likely secondary to increased clotting tendency. He had a spontaneously formed blood clot in his left anterior descending coronary artery. In the setting of hypo-albuminemia (which has occurred because of obligate losses of protein from lymphuria), he has increased production of factor VIII levels and increased clotting tendency. In addition, because of obligate and unregulated fluid losses he has chronic dehydration, miscrovascular ischemia and secondary polycythemia. This polycythemia further increases his risk of hypercoagulability.
authors.affiliation: Department of Medicine, Montefiore Medical Center, Bronx, NY, USA. lgolesta@montefiore.org
authors.forename: Ladan
authors.initials: L
authors.lastname: Golestaneh
authors.forename: Sabine
authors.initials: S
authors.lastname: Karam
authors.forename: Janis
authors.initials: J
authors.lastname: Lawrence
authors.forename: Sara
authors.initials: S
authors.lastname: Yang
authors.forename: Mark
authors.initials: M
authors.lastname: Greenberg
mesh_terms: D000328:Adult; D002908:Chronic Disease; D002913:Chyle; D006801:Humans; D034141:Hypoalbuminemia / Q000150:complications*; D008297:Male; D011507:Proteinuria / Q000150:complications*; D019851:Thrombophilia / Q000209:etiology*; D014556:Urine