[Synthesis and characteristics of new fluorescent probes based on cardiolipin].
New fluorescent lipid probes, cardiolipin derivatives AV12-CL and B7-CL, bearing the residues of 12-(9-anthryl)-11E-dodecenoic and 7-(4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacen-8-yl)heptanoic acid, respectively, have been synthesized by acylation of 1-lysocardiolipin, which had been obtained from bovine heart cardiolipin by enzymatic hydrolysis with bacterial lipase. The resulting probes are intended for the study of protein-anionic phospholipid interactions.
Boldyrev
I A
IA
Pavlova
Iu B
IuB
Molotkovskiĭ
Iu G
IuG
D000215:Acylation; D002308:Cardiolipins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods
D002308:Cardiolipins; D005456:Fluorescent Dyes