title: Analysis of blood pressure dynamics in male and female rats using the continuous wavelet transform.
abstract: We study gender-related particularities in cardiovascular responses to stress and nitric oxide (NO) deficiency in rats using HR, mean arterial pressure (MAP) and a proposed wavelet-based approach. Blood pressure dynamics is analyzed: (1) under control conditions, (2) during immobilization stress and recovery and (3) during nitric oxide blockade by N(G)-nitro-L-arginine-methyl ester (L-NAME). We show that cardiovascular sensitivity to stress and NO deficiency depends upon gender. Actually, in females the chronotropic effect of stress is more pronounced, while the pressor effect is weakened compared with males. We conclude that females demonstrate more favorable patterns of cardiovascular responses to stress and more effective NO control of cardiovascular activity than males.
authors.affiliation: Physics Department, Saratov State University, 410026 Saratov, Russia. pavlov@chaos.ssu.runnet.ru
authors.forename: A N
authors.initials: AN
authors.lastname: Pavlov
authors.forename: A A
authors.initials: AA
authors.lastname: Anisimov
authors.forename: O V
authors.initials: OV
authors.lastname: Semyachkina-Glushkovskaya
authors.forename: E G
authors.initials: EG
authors.lastname: Matasova
authors.forename: J
authors.initials: J
authors.lastname: Kurths
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D019277:Entropy; D005260:Female; D008297:Male; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D009569:Nitric Oxide / Q000502:physiology; D051381:Rats; D012727:Sex Characteristics; D013315:Stress, Psychological / Q000503:physiopathology
chemical_list: D009569:Nitric Oxide; D019331:NG-Nitroarginine Methyl Ester