title: Colonization of the tip of a thoracic catheter by Enterococcus faecalis resistant to vancomycin and linezolid.
abstract: We report the isolation of Enterococcus faecalis resistant to vancomycin and linezolid from the tip of a thoracic drainage catheter in an elderly patient. He was treated with vancomycin for a pleural empyema due to a meticillin-resistant Staphylococcus aureus but never received linezolid. A surveillance rectal swab yielded both linezolid-susceptible and -resistant strains, and the two isolates were not genotypically related. Careful monitoring for linezolid-resistance is critical to avoid potential therapy failure and transmission of resistant E. faecalis.
authors.affiliation: Dipartimento di Medicina di Laboratorio, Struttura Complessa Microbiologia, Azienda Ospedaliero-Universitaria 'Ospedali Riuniti' di Trieste, Trieste, Italy.|Dipartimento di Scienze Biomediche, Università di Trieste, Trieste, Italy.
authors.forename: Franca
authors.initials: F
authors.lastname: Cian
authors.affiliation: Struttura Complessa Malattie Infettive, Azienda Ospedaliero-Universitaria 'Ospedali Riuniti' di Trieste, Trieste, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Luzzati
authors.affiliation: Dipartimento di Medicina di Laboratorio, Struttura Complessa Microbiologia, Azienda Ospedaliero-Universitaria 'Ospedali Riuniti' di Trieste, Trieste, Italy.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Deiana
authors.affiliation: Dipartimento di Medicina di Laboratorio, Struttura Complessa Microbiologia, Azienda Ospedaliero-Universitaria 'Ospedali Riuniti' di Trieste, Trieste, Italy.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Ferrantelli
authors.affiliation: Dipartimento di Scienze Biomediche, Università di Trieste, Trieste, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Tonin
authors.affiliation: Dipartimento di Scienze Biomediche, Università di Trieste, Trieste, Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Lagatolla
authors.affiliation: Dipartimento di Scienze Biomediche, Università di Trieste, Trieste, Italy.
authors.forename: Lucilla
authors.initials: L
authors.lastname: Dolzani
mesh_terms: D000081:Acetamides / Q000494:pharmacology*; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002404:Catheterization / Q000009:adverse effects*; D024901:Drug Resistance, Multiple, Bacterial; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D000069349:Linezolid; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D023303:Oxazolidinones / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy; D014640:Vancomycin / Q000494:pharmacology*
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D014640:Vancomycin; D000069349:Linezolid