title: Comparative assessment of Helicobacter pylori colonization in children tonsillar tissues.
abstract: OBJECTIVE
  The objective was to survey the results of RUT (rapid urease test) in children tonsillar tissues.
  
  
  METHODS
  In a prospective clinical study 285 children (4-14 years) tonsillar tissue tested with RUT (rapid urease test) and histopathologic biopsy and simultaneously serum IgG Helicobacter pylori level was measured for all patients.
  
  
  RESULTS
  One hundred and thirteen patients (39.6%) were positive to H. pylori in histopathologic examination. Forty patients (14%) had positive RUT and 15 patients had positive serum IgG anti-H. pylori level. In 40 patients the results in both histopathology and RUT were positive (P=0.000) although in 172 patients the results in both histopatologhic and RUT were negative (P=0.000).
  
  
  CONCLUSIONS
  This study showed that H. pylori was present in tonsillar tissue and RUT is not sensitive enough for diagnosis of H. pylori in tonsillar tissue. Indicating that H. pylori has a possible role in reservoir of H. pylori in children.
authors.affiliation: Liver and Gastrointestinal Research Center, Tabriz University (Medical Sciences), Iran.
authors.forename: Yalda
authors.initials: Y
authors.lastname: Jabbari Moghaddam
authors.forename: Mandana
authors.initials: M
authors.lastname: Rafeey
authors.forename: Reza
authors.initials: R
authors.lastname: Radfar
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001944:Breath Tests / Q000379:methods; D002648:Child; D002675:Child, Preschool; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G; D014066:Palatine Tonsil / Q000382:microbiology* / Q000473:pathology; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods; D014510:Urease / Q000378:metabolism
chemical_list: D007074:Immunoglobulin G; D014510:Urease