title: Perp and pemphigus: a disease of desmosome destabilization.
abstract: In this issue, Nguyen et al. demonstrate a role for Perp in desmosome assembly and trafficking and pemphigus IgG-mediated acantholysis, providing further insights into the complexity of desmosome structure and regulation.
authors.affiliation: Department of Dermatology, University of North Carolina, Chapel Hill, North Carolina 27599-7287, USA.
authors.forename: Meryem
authors.initials: M
authors.lastname: Bektas
authors.forename: David S
authors.initials: DS
authors.lastname: Rubenstein
mesh_terms: D003896:Desmosomes / Q000378:metabolism* / Q000473:pathology*; D016147:Genes, Tumor Suppressor; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D010392:Pemphigus / Q000378:metabolism* / Q000473:pathology*; D021381:Protein Transport / Q000502:physiology
chemical_list: D008565:Membrane Proteins; C416404:PERP protein, human