Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza.
Magano
Javier
J
Pfizer Global Research & Development, Eastern Point Road, Groton, Connecticut 06340, USA. Javier.Magano@Pfizer.com
D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy*; D009439:Neuraminidase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D053139:Oseltamivir / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D053243:Zanamivir / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use
D000998:Antiviral Agents; D004791:Enzyme Inhibitors; D053139:Oseltamivir; D009439:Neuraminidase; D053243:Zanamivir