title: Molecular typing of methicillin-susceptible Staphylococcus aureus isolates collected in the Yogyakarta area in Indonesia, 2006.
abstract: The characterization of 62 community-associated methicillin-sensitive Staphylococcus aureus (MSSA) isolates from 440 individuals in the Yogyakarta area of Indonesia in 2006 showed that: (i) almost half of the isolates were associated with methicillin-resistant S. aureus lineages [clonal complex (CC)1, CC8 and CC45] and (ii) ten Panton-Valentine leukocidin-positive isolates were associated with CC1 (n = 7), CC30 (n = 1) and CC51 (n = 2). The high Panton-Valentine leukocidin prevalence (16%) among S. aureus is of concern because these strains can cause severe infections and the introduction of staphylococcal cassette chromosome mec into virulent and epidemic MSSA could pose a serious public health threat.
authors.affiliation: Department of Medical Microbiology, Maastricht University Medical Center, Maastricht, The Netherlands. ruud.deurenberg@mumc.nl
authors.forename: R H
authors.initials: RH
authors.lastname: Deurenberg
authors.forename: P S
authors.initials: PS
authors.lastname: Beisser
authors.forename: M J
authors.initials: MJ
authors.lastname: Visschers
authors.forename: C
authors.initials: C
authors.lastname: Driessen
authors.forename: E E
authors.initials: EE
authors.lastname: Stobberingh
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology*; D005098:Exotoxins / Q000235:genetics; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D007956:Leukocidins / Q000235:genetics; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D017720:Molecular Epidemiology / Q000379:methods; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin