Menstrual cycle length in relation to antimüllerian hormone and follicle-stimulating hormone.
OBJECTIVE
To find a relationship between serum antimüllerian hormone (AMH) and follicle-stimulating hormone (FSH) levels in women with regular menstruation.


METHODS
A cross-sectional study was conducted on 71 women with male factor infertility. Serum level of AMH and FSH and mean menstrual cycle length (MCL) were measured. The study aimed to find the correlation between serum AMH and FSH levels in normal menstrual cycles.


RESULTS
Our study included 71 women. Of them, 53 had an MCL of 25-35 days (group A) and 18 women had an MCL > 35 days (group B). The mean AMH in group A and group B differed significantly (4.11 +/- 3.4 ng/L, 7.42 +/- 4.34 ng/L, respectively; p < 0.008). In group A, reverse correlation between FSH and AMH was found (r = -0.32, p < 0.03).


CONCLUSIONS
AMH level had significant difference with FSH in patients of group A who had FSH > or = 12 IU/L or FSH < 12 IU/L (1.02 +/- 0.7, 4.8 +/- 3.5 ng/L, respectively; p < 0.02). Serum AMH level with threshold of 2.2 ng/L had sensitivity of 75% and specificity of 82% in predicting FSH > or = 12 IU/L on the third day of menstrual cycle.
Rashidi
Batool Hossein
BH
Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran. bhrashidi@tums.ac.ir
Abediasl
Zhila
Z
Tehraninejad
Ensiyeh Shahrokh
ES
Shariat
Mamak
M
Mahdavi
Atossa
A
D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007248:Infertility, Male; D008297:Male; D008597:Menstrual Cycle / Q000502:physiology*; D011247:Pregnancy; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors
D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone