Celiac plexus neurolysis for pain relief in pancreatic cancer.
Palliation of pain in pancreatic cancer often requires a multidisciplinary approach, with options including oral analgesics, chemoradiotherapy, and celiac plexus neurolysis (CPN). Although CPN may be performed endoscopically, percutaneously, or surgically, endoscopic ultrasonography (EUS)-guided CPN is becoming more commonplace, given the overall improved real-time visualization and reduced risk of major (neurologic) complications. Regardless of the technique used, CPN may have a long-lasting benefit in between 70% and 90% of patients with pancreatic cancer.
Moore
Jill C
JC
University of Utah School of Medicine, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Huntsman Cancer Center, Salt Lake City, Utah, USA.
Adler
Douglas G
DG
D015746:Abdominal Pain / Q000209:etiology / Q000628:therapy*; D000779:Anesthetics, Local / Q000008:administration & dosage; D002447:Celiac Plexus; D003714:Denervation / Q000009:adverse effects / Q000379:methods*; D000431:Ethanol / Q000008:administration & dosage; D006801:Humans; D010166:Palliative Care / Q000379:methods*; D010179:Pancreas / Q000294:innervation*; D010190:Pancreatic Neoplasms / Q000150:complications*; D012997:Solvents / Q000008:administration & dosage; D018084:Ultrasonography, Interventional / Q000379:methods
D000779:Anesthetics, Local; D012997:Solvents; D000431:Ethanol