title: Changes in endolymphatic hydrops in a patient with Meniere's disease observed using magnetic resonance imaging.
abstract: We describe a case report of a patient with Meniere's disease whose changes in endolymphatic hydrops were observed using magnetic resonance imaging (MRI). Gadolinium was injected intratympanically through the tympanic membrane, and MRI scans performed with a 3-T MRI unit revealed endolymphatic hydrops inside the perilymphatic space filled with gadolinium. We evaluated the relationship between the image findings and hearing level. The correlation between the degree of endolymphatic hydrops observed by MRI and hearing level in patients with Meniere's disease offers a promising new method to study the progression of Meniere's disease.
authors.affiliation: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Japan. michsone@med.nagoya-u.ac.jp
authors.forename: Michihiko
authors.initials: M
authors.lastname: Sone
authors.forename: Shinji
authors.initials: S
authors.lastname: Naganawa
authors.forename: Masaaki
authors.initials: M
authors.lastname: Teranishi
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nakata
authors.forename: Naomi
authors.initials: N
authors.lastname: Katayama
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakashima
mesh_terms: D000328:Adult; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D002150:Caloric Tests; D003287:Contrast Media / Q000008:administration & dosage; D018450:Disease Progression; D018159:Endolymphatic Hydrops / Q000175:diagnosis* / Q000503:physiopathology; D019054:Evoked Potentials, Motor / Q000502:physiology; D019786:Gadolinium DTPA; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology; D012680:Sensitivity and Specificity; D013575:Syncope / Q000209:etiology / Q000503:physiopathology
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA