In vitro effect of oxidized dextrans on peritoneal cells.
We studied the dependence of in vitro dextran biocompatibility on the method of oxidation of 35-kDa dextran. The biocompatibility of dextran oxidized with potassium permanganate was higher compared to that obtained by radiochemical oxidation. It was related to the formation of peroxide compounds during radiochemical oxidation.
Shkurupiy
V A
VA
Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. sck@soramn.ru
Arkhipov
S A
SA
Troitsky
A V
AV
Luzgina
N G
NG
Zaikovskaja
M V
MV
Gulyaeva
E P
EP
Bistrova
T N
TN
Ufimceva
E G
EG
Iljin
D A
DA
Akhramenko
E S
ES
D000818:Animals; D000925:Anticoagulants / Q000737:chemistry / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003911:Dextrans / Q000737:chemistry* / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010084:Oxidation-Reduction; D010537:Peritoneum / Q000166:cytology*; D011196:Potassium Permanganate / Q000737:chemistry; D011854:Radiochemistry
D000925:Anticoagulants; D003911:Dextrans; D011196:Potassium Permanganate