title: Effects of whole-body vibration on prostate morphology.
abstract: The peculiarities of the prostate remodeling caused by long-term whole-body vibration were investigated. Vibrational prostatopathy was characterized by more incident and pronounced decrease in prostate size, blurred contours, and appearance of sites with changed density (fibrosis, calcification, cysts) in central and peripheral zones of the gland. Vibrogenic prostate remodeling is determined by marked reduction of microvessel and prostatic glands, particularly in the central (periurethral) part, smooth muscle cell hyperplasia and hypertrophy, and marked fibrosis of the stroma in the absence of inflammatory cellular infiltration. Morphological data describing reduction of microvessels in the prostate caused by whole-body vibration correlate with Doppler scanning data indicating reduced perfusion of the organ.
authors.affiliation: Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Barnaul, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Ananev
authors.forename: E L
authors.initials: EL
authors.lastname: Lushnikova
authors.forename: N A
authors.initials: NA
authors.lastname: Abdullaev
authors.forename: A I
authors.initials: AI
authors.lastname: Neymark
mesh_terms: D004847:Epithelial Cells / Q000473:pathology; D006801:Humans; D008297:Male; D055806:Microvessels / Q000473:pathology; D008875:Middle Aged; D032389:Myocytes, Smooth Muscle / Q000473:pathology; D009929:Organ Size; D011467:Prostate / Q000473:pathology*; D018615:Ultrasonography, Doppler, Color; D014732:Vibration / Q000009:adverse effects*