[Congenital cytomegaly--advances in diagnosis and therapy].
Authors presented of a cytomegalovirus characteristics, its existing in human population and rare clinical presentation in immunocompetent persons (including pregnant women) after primary infection. The vertical transmission from mother to the fetus and the mode of acquisition of infection in perinatal period as well as symptoms of congenital cytomegaly together with late sequelae are also under discussion. Authors stressed, that advances in improvements in the diagnosis of maternal, fetal and newborn infection are not outpaced with improvements in the antiviral treatment of fetuses and infants, but improvement or stabilization of hearing loss after ganciclovir therapy is observed. Routine serologic screening for an immunity (mothers and newborns) is still controversial. At present, the prevention of CMV infection is the ideal solution, especially the education people about CMV and routes of transmission.
Milewska-Bobula
Bogumiła
B
Klinika Niemowleca Instytutu Pomnik-Centrum Zdrowia Dziecka w Warszawie.
Lipka
Bozena
B
D000653:Amniotic Fluid / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000175:diagnosis* / Q000517:prevention & control; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000517:prevention & control / Q000821:virology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control / Q000821:virology; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000517:prevention & control*; D011296:Prenatal Diagnosis; D012307:Risk Factors; D012698:Serologic Tests
D000914:Antibodies, Viral; D007075:Immunoglobulin M