title: Advances in dengue vaccine development.
abstract: Dengue viruses are the most important arboviruses causing human disease. Expansion of the disease in recent decades to include more geographical areas of the world, an appreciation of the disease burden and market potentials have spurred a flurry of activity in the development of vaccines to combat dengue viruses. Recent progress in this area and some of the obstacles associated with this development are discussed.
authors.affiliation: Naval Medical Research Center, Silver Spring, MD, USA. Kanakatte.raviprakas@med.navy.mil
authors.forename: Kanakatte
authors.initials: K
authors.lastname: Raviprakash
authors.forename: Gabriel
authors.initials: G
authors.lastname: Defang
authors.forename: Timothy
authors.initials: T
authors.lastname: Burgess
authors.forename: Kevin
authors.initials: K
authors.lastname: Porter
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D003715:Dengue / Q000276:immunology* / Q000517:prevention & control*; D053059:Dengue Vaccines / Q000008:administration & dosage / Q000276:immunology*; D003716:Dengue Virus / Q000235:genetics / Q000276:immunology*; D006801:Humans; D014330:Tropical Medicine / Q000639:trends*; D014611:Vaccination; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000276:immunology; D022223:Vaccines, Subunit / Q000008:administration & dosage / Q000276:immunology
chemical_list: D053059:Dengue Vaccines; D019444:Vaccines, DNA; D022223:Vaccines, Subunit