Structures of kinesin motor proteins.
Almost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X-ray crystallography and cryoelectron microscopy 3-D analysis on kinesin motor domains complexed to microtubules.
Marx
Alexander
A
Max-Planck-Unit for Structural Molecular Biology, c/o DESY, Hamburg, Germany. marx@mpasmb.desy.de
Hoenger
Andreas
A
Mandelkow
Eckhard
E
D000818:Animals; D020285:Cryoelectron Microscopy; D018360:Crystallography, X-Ray; D006801:Humans; D016547:Kinesins / Q000737:chemistry*; D008870:Microtubules / Q000737:chemistry; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
D016547:Kinesins