title: [Takotsubo syndrome from original description up to now].
abstract: Stress-induced cardiomyopathy, also known as takotsubo syndrome, imitates an acute ST elevation myocardial infarction or an acute coronary syndrome, but without concomitant coronary artery disease. It mainly affects postmenopausal women, but no established epidemiologic data of this syndrome are available to date. Furthermore, the underlying etiologies are still largely unknown. The most frequently described trigger is strong emotional stress. Supportive therapy with aspirin, beta-blockers and angiotensin-converting enzyme inhibitors is recommended. The abnormal kinetics usually reverse or improve within 4-5 weeks. Compared with acute myocardial infarction, takotsubo cardiomyopathy carries a favorable prognosis. However, severe complications, including ventricular fibrillation and cardiogenic shock, may still occur.
authors.affiliation: Innere Medizin-Kardiologie, Universitätsklinikum Magdeburg, Magdeburg, Germany. samir.said@med.ovgu.de
authors.forename: Samir M
authors.initials: SM
authors.lastname: Said
authors.forename: Khaled
authors.initials: K
authors.lastname: Albouaini
authors.forename: Joerg
authors.initials: J
authors.lastname: Herold
authors.forename: Judit
authors.initials: J
authors.lastname: Hahn
authors.forename: Steffen
authors.initials: S
authors.lastname: Brucks
authors.forename: Hendrik
authors.initials: H
authors.lastname: Schmidt
authors.forename: Alexander
authors.initials: A
authors.lastname: Schmeisser
authors.forename: Roland
authors.initials: R
authors.lastname: Prondzinsky
authors.forename: Ruediger C
authors.initials: RC
authors.lastname: Braun-Dullaeus
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000367:Age Factors; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage; D000818:Animals; D001241:Aspirin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D011379:Prognosis; D012307:Risk Factors; D012737:Sex Factors; D012770:Shock, Cardiogenic / Q000175:diagnosis; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000523:psychology
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin