title: Forkhead box H1 (FOXH1) sequence variants in ventricular septal defect.
abstract: OBJECTIVE
  To investigate the possible genetic role of FOXH1 in the pathogenesis of ventricular septal defect (VSD).
  
  
  METHODS
  301 VSD Chinese patients and 111 Chinese patients with the other subtypes of congenital heart defects were investigated for mutations in the FOXH1 gene by direct sequencing.
  
  
  RESULTS
  Four variants were found among the isolated VSD patients, including one pathogenic mutation (c.659_660ins.C).
authors.forename: Binbin
authors.initials: B
authors.lastname: Wang
authors.forename: Jinting
authors.initials: J
authors.lastname: Yan
authors.forename: Rui
authors.initials: R
authors.lastname: Mi
authors.forename: Shiyi
authors.initials: S
authors.lastname: Zhou
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Xie
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Xu
authors.initials: X
authors.lastname: Ma
mesh_terms: D000595:Amino Acid Sequence; D044466:Asian People / Q000235:genetics*; D015331:Cohort Studies; D051858:Forkhead Transcription Factors / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics
chemical_list: C510350:FOXH1 protein, human; D051858:Forkhead Transcription Factors