title: Bioinformatics comparison of G protein of Isfahan virus with the same proteins of two other closely related viruses of the genus vesiculovirus.
abstract: Since there are not much experimental data available about different structural properties of Isfahan virus (ISFV), in the present investigation, computational study of G protein of ISFV was performed and the results were compared with G proteins of Chandipura virus (CHPV) and Piry virus (PV). Calculation of amino acid compositions of G proteins of viruses was done by PseAAC server. Predictions of localization, sequence of signal peptides, C, N and O glycosylation sites, transmembrane helices, cysteine bond positions and B cell epitopes of G proteins were performed by Virus-PLoc, Signal-CF, EnsembleGly, MemBrain, DiANNA and BCPREDS servers respectively. Similarities and differences between these glycoproteins were predicted and discussed.
authors.affiliation: Department of Biology, College of Sciences, Shiraz University, Shiraz 71454, Iran. mohabat@shirazu.ac.ir
authors.forename: Hassan
authors.initials: H
authors.lastname: Mohabatkar
authors.forename: Sasan
authors.initials: S
authors.lastname: Mohsenzadeh
mesh_terms: D000595:Amino Acid Sequence; D019295:Computational Biology; D004220:Disulfides / Q000737:chemistry; D018985:Epitopes, B-Lymphocyte / Q000032:analysis; D006023:Glycoproteins / Q000737:chemistry / Q000235:genetics*; D006031:Glycosylation; D021382:Protein Sorting Signals; D017433:Protein Structure, Secondary; D016415:Sequence Alignment; D018116:Vesiculovirus / Q000145:classification / Q000235:genetics*; D015678:Viral Structural Proteins / Q000737:chemistry*
chemical_list: D004220:Disulfides; D018985:Epitopes, B-Lymphocyte; D006023:Glycoproteins; D021382:Protein Sorting Signals; D015678:Viral Structural Proteins