title: Characterisation of mixed lithium dodecyl sulphate/lithium perfluorooctanesulphonate pseudo-stationary phases in MEKC.
abstract: Lipophilicity and methylene selectivity of mixed pseudo-stationary phases (PSPs) (containing lithium dodecyl sulphate (LDS) and lithium perfluorooctanesulphonate (LiPFOS) in different molar ratios) applied in MEKC have been investigated. Micellar proportion (t(prop,mic), a quantity expressing that how much time is spent by the analyte in the micellar phase related to its whole migration time), CLOGP(50) value (showing the value of hydrophobicity of a molecule spending exactly 50% of its migration time in the PSP) and methylene selectivity have been determined for different LDS/LiPFOS mixed phases. Values of the above-mentioned parameters have been determined for analytes with different chemical structures (alkylbenzene and alkylphenone homologous series, alcohols). Good linear correlation was obtained between either the micellar proportion, CLOGP(50), or methylene selectivity and the phase composition for the mixed phases. Lipophilicity and methylene selectivity of the mixed LDS/LiPFOS PSPs can be calculated and can continuously be changed by mixing the two single phases (LDS and LiPFOS) in the appropriate (and calculable) portion.
authors.affiliation: Pathobiochemistry Research Group of Hungarian Academy of Sciences and Semmelweis University, Hungary. andras.varga@kkk.org.hu
authors.forename: András
authors.initials: A
authors.lastname: Varga
authors.forename: Mónika
authors.initials: M
authors.lastname: Huszár
authors.forename: Zsófia
authors.initials: Z
authors.lastname: Dobos
authors.forename: Eva
authors.initials: E
authors.lastname: Kiss
authors.forename: Anikó
authors.initials: A
authors.lastname: Horváth
authors.forename: Miklós
authors.initials: M
authors.lastname: Idei
mesh_terms: D017738:Alkanesulfonic Acids / Q000737:chemistry*; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D005466:Fluorocarbons / Q000737:chemistry*; D006838:Hydrocarbons / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D016014:Linear Models; D018020:Lithium Compounds / Q000737:chemistry*; D008823:Micelles; D008956:Models, Chemical; D012680:Sensitivity and Specificity; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry*
chemical_list: D017738:Alkanesulfonic Acids; D005466:Fluorocarbons; D006838:Hydrocarbons; D018020:Lithium Compounds; D008823:Micelles; D012967:Sodium Dodecyl Sulfate; C076994:perfluorooctane sulfonic acid; C028913:dodecyl sulfate