Acute hemifacial dystonia possibly induced by clebopride.
Dystonic reactions produce twisting and repetitive movements or abnormal posturing. Severe dystonic reactions have been shown to occur in concert with numerous medications. This report details the case of a patient who developed hemifacial dystonia as acute side reaction from administration of clebopride for dyspeptic prophylaxis. When the drug was immediately stopped, the dystonic posture disappeared completely within 2 weeks. The use of clebopride may be associated with not only a reversible or persistent parkinsonism syndrome but also hemifacial dystonia; therefore, attention must be drawn to this possible side effect.
Bosco
Domenico
D
Operative Unit of Neurology, S. Giovanni di Dio Hospital, Crotone, Italy. nico_bosco@libero.it
Plastino
Massimiliano
M
Marcello
Maria Giovanna
MG
Mungari
Pasquale
P
Fava
Antonietta
A
D000369:Aged, 80 and over; D000932:Antiemetics / Q000009:adverse effects*; D001549:Benzamides / Q000009:adverse effects*; D020821:Dystonic Disorders / Q000139:chemically induced*; D005260:Female; D006801:Humans
D000932:Antiemetics; D001549:Benzamides; C014417:clebopride