title: Study on acetylcholinesterase inhibition induced by endogenous neurotoxin with an enzyme-semiconductor photoelectrochemical system.
abstract: The integration of Au-doped TiO(2) nanotubes with biomolecule acetylcholinesterase (AChE) yields a novel AChE-Au-TiO(2) hybrid system, which provides a new rapid and valid photoelectrochemical approach to the determination of AChE inhibition induced by endogenous neurotoxin.
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200062, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.forename: Ya-Rui
authors.initials: YR
authors.lastname: An
authors.forename: Xiao-Min
authors.initials: XM
authors.lastname: Luo
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Jiao-Hong
authors.initials: JH
authors.lastname: Zheng
authors.forename: Lin-Lin
authors.initials: LL
authors.lastname: Tang
authors.forename: Qing-Jiang
authors.initials: QJ
authors.lastname: Wang
authors.forename: Zhong-Hai
authors.initials: ZH
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Li-Tong
authors.initials: LT
authors.lastname: Jin
mesh_terms: D000110:Acetylcholinesterase / Q000187:drug effects* / Q000378:metabolism; D015374:Biosensing Techniques / Q000379:methods; D002800:Cholinesterase Inhibitors / Q000737:chemistry*; D006046:Gold; D007546:Isoquinolines / Q000494:pharmacology*; D007700:Kinetics; D043942:Nanotubes; D009498:Neurotoxins / Q000494:pharmacology*; D010777:Photochemistry; D012666:Semiconductors; D014025:Titanium
chemical_list: D002800:Cholinesterase Inhibitors; D007546:Isoquinolines; C089303:N-methylsalsolinium; D009498:Neurotoxins; C009495:titanium dioxide; D006046:Gold; D014025:Titanium; D000110:Acetylcholinesterase