title: Mechanical ventilation of six dogs anaesthetised with isoflurane or sevoflurane delivered by a Komesaroff anaesthetic machine.
abstract: After intravenous induction, six beagles were connected to a Komesaroff machine provided with a single in-circuit vaporiser and ventilated mechanically at either nine or 14 breaths/minute while anaesthetised with either isoflurane or sevoflurane. The vaporiser was initially set at position 4/4 (fully open) and the anaesthetic concentrations were measured after one and five minutes; the vaporiser was then set at the lowest setting able to maintain anaesthesia. Cardiorespiratory variables were measured throughout the study. In most cases anaesthesia was maintained at setting 1/4 with isoflurane and at setting 1.5/4 or 2/4 with sevoflurane.
authors.affiliation: Departamento de Medicina y Cirugía Animal, Universidad de Murcia, Campus de Espinardo, 30100 Espinado, Murcia, Spain. laredo@um.es
authors.forename: F G
authors.initials: FG
authors.lastname: Laredo
authors.forename: E
authors.initials: E
authors.lastname: Belda
authors.forename: M
authors.initials: M
authors.lastname: Escobar
mesh_terms: D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation / Q000379:methods / Q000662:veterinary*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D000818:Animals; D018592:Cross-Over Studies; D004285:Dogs / Q000502:physiology*; D005260:Female; D007530:Isoflurane / Q000008:administration & dosage*; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D009330:Nebulizers and Vaporizers / Q000662:veterinary; D012119:Respiration; D012121:Respiration, Artificial / Q000662:veterinary*; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D007530:Isoflurane