title: Neurosurgical rescue of bradycardia induced by intracerebral hypertension: a case report and review of the literature.
abstract: Brain metastases usually occur secondary to lung, breast, unknown primary, melanoma, and colon cancers. A growing tumor in the brain is commonly associated with edema and increased intracranial pressure (ICP). Common signs and symptoms due to increased ICP or brain edema include headache, nausea, and vomiting. One of the main treatment modalities in the management of brain metastases is whole-brain radiation. However, increased ICP may lead to acute deterioration of the neurologic status due to development of radiation-induced edema. Therefore, alternative management options should be considered for these patients to avoid complications from whole-brain radiation treatment. We discuss the case of a brain metastases patient who presented with bradycardia induced by brain edema.
authors.affiliation: Department of Radiation Oncology, Odette Cancer Centre, Toronto, Canada.
authors.forename: Harleen
authors.initials: H
authors.lastname: Bedi
authors.forename: Gunita
authors.initials: G
authors.lastname: Mitera
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
authors.forename: Farhad
authors.initials: F
authors.lastname: Pirouzmand
authors.forename: Juan
authors.initials: J
authors.lastname: Bilbao
authors.forename: Emily
authors.initials: E
authors.lastname: Sinclair
authors.forename: Alice
authors.initials: A
authors.lastname: Fitch
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
mesh_terms: D000328:Adult; D001919:Bradycardia / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D001929:Brain Edema / Q000150:complications*; D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000503:physiopathology; D019635:Neurosurgical Procedures; D012196:Review Literature as Topic