[Clinical and morphological characteristics of intraductal papillary mucinous tumors of the pancreas].
The paper presents the results of a comprehensive morphological study of the surgical material from 5 patients (males aged 49 to 69 years) with intraductal papillary mucinous tumors (IDPMT) of the pancreas. The pancreatobiliary type of IDPMT was established in 4 cases (one adenoma from the peripheral branches of the pancreatic duct, one IDPMT with the borderline malignancy potential from the major pancreatic duct, and two intraductal papillary mucinous carcinomas from the major pancreatic duct). The expression of MUC1 and MUC5AC, cytokeratins 7, 19, and 18 was immunohistochemically shown. One patient was diagnosed as having an enteric type of a tumor (IDPMT with the borderline malignancy from the major pancreatic duct), which was characterized by the expression in the MUC2 and MUC5AC cells and by that of cytokeratin 20.
Dubova
E A
EA
Shchegolev
A I
AI
D002288:Adenocarcinoma, Mucinous / Q000378:metabolism* / Q000473:pathology*; D000236:Adenoma / Q000378:metabolism* / Q000473:pathology*; D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000378:metabolism* / Q000473:pathology*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007633:Keratins / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged; D055271:Mucin 5AC / Q000096:biosynthesis; D018396:Mucin-1 / Q000096:biosynthesis; D009363:Neoplasm Proteins / Q000096:biosynthesis
C060192:MUC1 protein, human; C524678:MUC5AC protein, human; D055271:Mucin 5AC; D018396:Mucin-1; D009363:Neoplasm Proteins; D007633:Keratins