title: [Danazol - effective second line therapy in idiopathic thrombocytopenic purpura in children. Three case reports].
abstract: Danazol is an accredited second line drug for idiopathic thrombocytopenic purpura (ITP) in adults. There are very few positions in the literature about using danazol in children, although some articles quote its evident efficacy. In this paper we present three cases of children treated with danazol. The routine treatment in these ITP cases was ineffective. The result was stabilization of platelet count and avoidance of splenectomy.
authors.affiliation: Katedra i Klinika Pediatrii, Hematologii i Onkologii WUM w Warszawie, ul. Marszałkowska 24, 00-576 Warszawa, Poland. aszmydki@tlen.pl.
authors.forename: Anna
authors.initials: A
authors.lastname: Szmydki-Baran
authors.forename: Anna
authors.initials: A
authors.lastname: Adamowicz-Salach
authors.forename: Sydonia
authors.initials: S
authors.lastname: Gołebiowska-Staroszczyk
mesh_terms: D002648:Child; D003613:Danazol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D013156:Splenectomy; D017211:Treatment Failure
chemical_list: D003613:Danazol