title: [Central auditory prosthesis].
abstract: Deaf patients with severe sensory hearing loss can benefit from a cochlear implant (CI), which stimulates the auditory nerve fibers. However, patients who do not have an intact auditory nerve cannot benefit from a CI. The majority of these patients are neurofibromatosis type 2 (NF2) patients who developed neural deafness due to growth or surgical removal of a bilateral acoustic neuroma. The only current solution is the auditory brainstem implant (ABI), which stimulates the surface of the cochlear nucleus in the brainstem. Although the ABI provides improvement in environmental awareness and lip-reading capabilities, only a few NF2 patients have achieved some limited open set speech perception. In the search for alternative procedures our research group in collaboration with Cochlear Ltd. (Australia) developed a human prototype auditory midbrain implant (AMI), which is designed to electrically stimulate the inferior colliculus (IC). The IC has the potential as a new target for an auditory prosthesis as it provides access to neural projections necessary for speech perception as well as a systematic map of spectral information. In this paper the present status of research and development in the field of central auditory prostheses is presented with respect to technology, surgical technique and hearing results as well as the background concepts of ABI and AMI.
authors.affiliation: Hals-Nasen-Ohrenklinik, Medizinische Hochschule Hannover, Hannover, Germany. lenarz.thomas@mh-hannover.de
authors.forename: T
authors.initials: T
authors.lastname: Lenarz
authors.forename: H
authors.initials: H
authors.lastname: Lim
authors.forename: G
authors.initials: G
authors.lastname: Joseph
authors.forename: G
authors.initials: G
authors.lastname: Reuter
authors.forename: M
authors.initials: M
authors.lastname: Lenarz
mesh_terms: D003638:Deafness / Q000534:rehabilitation*; D046690:Deep Brain Stimulation / Q000295:instrumentation* / Q000379:methods*; D019544:Equipment Failure Analysis; D006801:Humans; D019736:Prostheses and Implants; D011474:Prosthesis Design