title: [Hereditary angioedema: a case series and bibliographic update].
abstract: BACKGROUND
  Hereditary angioedema is an autosomal dominant inherited condition that is characterized by the local development of edema of the skin, subcutaneous tissue, and the walls of almost any organ, including the gastrointestinal and upper respiratory tracts.
  
  
  OBJECTIVE
  To describe the clinical characteristics, diagnosis and treatment of six controlled patients with hereditary angioedema.
  
  
  METHODS
  This paper presents clinical characteristics of six patients, four of them members of the same family, and two, isolated, non-family related cases. This contribution is a review of the latest literature related to diagnosis and treatment of hereditary angioedema.
  
  
  RESULTS
  Hereditary angioedema is a rare clinical entity that has a complicated manifestation profile that requires to discard a wide series of differential diagnosis. Deeper knowledge of its genetics and physiopathology will allow us to explore new treatment alternatives in addition to those already available.
  
  
  CONCLUSIONS
  By diffusion of isolated cases or familial cases series, as presented in this paper, the disease recognition and timely treatment will be reached.
authors.affiliation: Servicio de Inmunología y Alergia, Unidad Medica de Alta Especialidad, Hospital Regional de Especialidades número 25, Centro Médico Nacional del Noreste, IMSS. alicialaram@prodigy.net.nx
authors.forename: Alicia Lara
authors.initials: AL
authors.lastname: Becerra
authors.forename: David Vega
authors.initials: DV
authors.lastname: Morales
mesh_terms: D000293:Adolescent; D000465:Algorithms; D054179:Angioedemas, Hereditary / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D001920:Bradykinin / Q000031:analogs & derivatives / Q000627:therapeutic use; D050718:Complement C1 Inhibitor Protein / Q000627:therapeutic use; D003613:Danazol / Q000627:therapeutic use; D018450:Disease Progression; D005260:Female; D006801:Humans; D007705:Kinins / Q000037:antagonists & inhibitors; D008297:Male; D010375:Pedigree; D010455:Peptides / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D050718:Complement C1 Inhibitor Protein; D007705:Kinins; D010455:Peptides; C511194:ecallantide; C065679:icatibant; D003613:Danazol; D001920:Bradykinin