title: Occupation-related pigmented macules on the sole with parallel-ridge pattern on dermatoscopy.
abstract: 27-year-old man presented with pigmented macules on the right sole, which showed a parallel-ridge pattern on dermatoscopy. His work for a chemical company involved handling para-phenylenediamine. Histological examination of a biopsy from a lesion did not find any proliferation of atypical melanocytes. Shaving the cornified layer of the lesions with a surgical knife resulted in the disappearance of macules. We speculate that para-phenylenediamine on the sole of the patient's work boot might have become blotted to the cornified layer of the cutis. This report adds a new occupation-related differential diagnosis for skin diseases showing a parallel-ridge pattern on dermatoscopy.
authors.affiliation: Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan. mtanioka@kuhp.kyoto-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Tanioka
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumura
authors.forename: A
authors.initials: A
authors.lastname: Utani
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Miyachi
mesh_terms: D000328:Adult; D002617:Chemical Industry; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology; D046169:Dermoscopy; D003937:Diagnosis, Differential; D005533:Foot Dermatoses / Q000139:chemically induced / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis; D010655:Phenylenediamines / Q000009:adverse effects; D010859:Pigmentation Disorders / Q000139:chemically induced / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis
chemical_list: D010655:Phenylenediamines; C029728:4-phenylenediamine