Stimulation of regeneration of hyaline cartilage in experimental osteochondral injury.
A model of osteochondral intra-articular defect in rats is presented. During spontaneous healing, the stage of formation of granulation tissue is followed by its replacement with bone and fibrous tissue. Chondroinductive properties of collagen 1 sponge used for defect filling manifested in the formation of fibrous cartilage with fields of hyaline cartilage. Filling of the defect with collagen 1 sponge containing bone powder stimulated regeneration of the bone tissue and hyaline cartilage.
Khubutiya
M Sh
MSh
N. V. Sklifosovsky Institute of Urgent Care, Moscow, Russia.
Kliukvin
I Yu
IY
Istranov
L P
LP
Khvatov
V B
VB
Shekhter
A B
AB
Vaza
A Yu
AY
Kanakov
I V
IV
Bocharova
V S
VS
D000818:Animals; D019902:Chondrocytes / Q000166:cytology*; D024042:Collagen Type I / Q000737:chemistry; D048091:Guided Tissue Regeneration / Q000379:methods*; D051457:Hyaline Cartilage / Q000601:surgery*; D007719:Knee Joint / Q000473:pathology / Q000601:surgery; D051381:Rats; D014182:Transplantation, Autologous; D014945:Wound Healing
D024042:Collagen Type I