title: Tracheal replacement by autogenous aorta.
abstract: BACKGROUND
  Tracheal defects may occur after trauma or prolonged intubation. Resection of tracheal tumors also poses a major challenge for substitution. In an effort to solve this problem, different techniques have been tried with little success. We report on a new animal model which showed acceptable results with fewer complications.
  
  
  METHODS
  We replaced 5 cm of cervical trachea in 10 dogs with harvested infra-renal aorta and repaired the aortic defect with Dacron graft.
  
  
  RESULTS
  Necropsy of the grafted aorta and anastomotic site revealed well healed anastomosis in all animals together with ciliated columnar epithelium coverage of grafted aorta and neovascularization of aortic wall.
  
  
  CONCLUSIONS
  Aortic graft is preferable to other substitutes because of less antigenicity, less vascularity, and no mucous secretions or peristalsis.
authors.affiliation: Department of Surgery, New York Hospital Queens, Weill College of Cornell University, New York, USA. farhadanoush@hotmail.com
authors.forename: Farhad
authors.initials: F
authors.lastname: Anoosh
authors.forename: Hossain
authors.initials: H
authors.lastname: Hodjati
authors.forename: Seifollah
authors.initials: S
authors.lastname: Dehghani
authors.forename: Nader
authors.initials: N
authors.lastname: Tanideh
authors.forename: Perikala V
authors.initials: PV
authors.lastname: Kumar
mesh_terms: D000818:Animals; D001012:Aorta, Abdominal / Q000637:transplantation*; D004195:Disease Models, Animal; D004285:Dogs; D019651:Plastic Surgery Procedures / Q000379:methods*; D019616:Thoracic Surgical Procedures / Q000379:methods*; D014133:Tracheal Diseases / Q000601:surgery*; D014182:Transplantation, Autologous / Q000379:methods*; D016896:Treatment Outcome; D014945:Wound Healing