title: [Diffusion weighted imaging combined with magnetic resonance conventional sequences for the diagnosis of rectal cancer].
abstract: OBJECTIVE
  To evaluate the clinical value of diffusion weighted imaging (DWI) combined with conventional sequences of magnetic resonance imaging (T1 and T2-weighted imaging) for the diagnosis of rectal cancer.
  
  
  METHODS
  DWI and conventional sequences were performed in 29 patients with endoscopically diagnosed rectal cancer and 15 patients without rectal cancer. Two doctors who were blind to the history of the patients interpreted the imaging findings. The sensitivity and specificity of conventional sequences with and without DWI were analyzed using receiver operating characteristic curve (ROC).
  
  
  RESULTS
  The areas under ROC were 0.915 and 0.930 for conventional sequences alone, and 0.990 and 0.994 for conventional sequences with DWI, respectively, indicating that although both of them were optimal methods for the diagnosis of rectal cancer, the accuracy of conventional sequences with DWI was significantly superior to that of conventional sequence alone (P < 0.05). The Kappa value was 0.850 for conventional sequences alone and 0.858 for DWI with conventional sequences.
  
  
  CONCLUSIONS
  DWI was necessary for the diagnosis of rectal cancer when performing conventional sequences.
authors.affiliation: Department of Radiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Guan-Ning
authors.initials: GN
authors.lastname: Cong
authors.forename: Ming-Wei
authors.initials: MW
authors.lastname: Qin
authors.forename: Hui
authors.initials: H
authors.lastname: You
authors.forename: Xiao-Zhen
authors.initials: XZ
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Xiao
authors.forename: Hui-Zhong
authors.initials: HZ
authors.lastname: Qiu
authors.forename: Bin
authors.initials: B
authors.lastname: Wu
authors.forename: Guo-Le
authors.initials: GL
authors.lastname: Lin
authors.forename: Chun-Ling
authors.initials: CL
authors.lastname: Meng
authors.forename: Wei
authors.initials: W
authors.lastname: Meng
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Dong
authors.initials: D
authors.lastname: Liu
authors.forename: Jin
authors.initials: J
authors.lastname: Xu
authors.forename: Yang
authors.initials: Y
authors.lastname: Jin
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D020700:Proctoscopes; D012372:ROC Curve; D012004:Rectal Neoplasms / Q000175:diagnosis*; D012680:Sensitivity and Specificity