Diversity of Anaplasma phagocytophilum strains, USA.
We analyzed the structure of the expression site encoding the immunoprotective protein MSP2/P44 from multiple Anaplasma phagocytophilum strains in the United States. The sequence of p44ESup1 had diverged in Ap-variant 1 strains infecting ruminants. In contrast, no differences were detected between A. phagocytophilum strains infecting humans and domestic dogs.
Morissette
Eric
E
University of Florida, Gainesville, Florida 32611-0880, USA.
Massung
Robert F
RF
Foley
Janet E
JE
Alleman
A Rick
AR
Foley
Patrick
P
Barbet
Anthony F
AF
D000595:Amino Acid Sequence; D041081:Anaplasma phagocytophilum / Q000145:classification* / Q000235:genetics*; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004283:Dog Diseases / Q000453:epidemiology / Q000382:microbiology; D004285:Dogs; D016873:Ehrlichiosis / Q000453:epidemiology* / Q000382:microbiology; D015964:Gene Expression Regulation, Bacterial; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA; D014481:United States / Q000453:epidemiology
D001425:Bacterial Outer Membrane Proteins; C488283:msp2 protein, Anaplasma phagocytophilum; C450839:p44 protein, Anaplasma phagocytophila