Nonequilibirum assembly, retroviruses, and conical structures.
We study the spontaneous assembly of viral shells composed of several identical subunits under nonequilibrium conditions. We find that within the basic continuum elasticity framework, the nonequilibrium assembly process is able to predict the formation of structures pertinent to retroviruses. Our minimal model of assembly yields a unified one-dimensional phase diagram in which the appearance of spherical, irregular, conical and cylindrical structures of retroviruses is seen to be governed by the spontaneous curvature of protein subunits.
Levandovsky
Artem
A
Department of Physics, University of California, Riverside California 92521, USA.
Zandi
Roya
R
D002213:Capsid / Q000502:physiology; D006678:HIV / Q000254:growth & development; D008954:Models, Biological; D012190:Retroviridae / Q000254:growth & development*