title: Optic nerve enhancement in Coats disease with secondary glaucoma.
abstract: Differentiating between Coats disease and retinoblastoma can be challenging. Magnetic resonance imaging typically is obtained when retinoblastoma is suspected to evaluate for a mass or optic nerve infiltration, the latter appearing as an enhancing lesion. We report a case of optic nerve enhancement observed in the setting of an acute secondary glaucoma in a patient with unilateral Coats retinopathy. Given the gravity of the decision to recommend enucleation on the basis of clinical findings consistent with retinoblastoma, physicians must be aware of the possibility of optic nerve enhancement in the setting of inflammation and raised intraocular pressure.
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, Oregon 97239-4197, USA.
authors.forename: Dilsher S
authors.initials: DS
authors.lastname: Dhoot
authors.forename: Jane L
authors.initials: JL
authors.lastname: Weissman
authors.forename: Rachel E
authors.initials: RE
authors.lastname: Landon
authors.forename: Mark
authors.initials: M
authors.lastname: Evans
authors.forename: J Timothy
authors.initials: JT
authors.lastname: Stout
mesh_terms: D000208:Acute Disease; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005682:Gadolinium; D005901:Glaucoma / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007429:Intraocular Pressure; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D019572:Retinal Neoplasms / Q000473:pathology; D015861:Retinal Neovascularization / Q000150:complications / Q000473:pathology*; D012175:Retinoblastoma / Q000473:pathology; D013684:Telangiectasis / Q000150:complications / Q000473:pathology*
chemical_list: D005682:Gadolinium