Biomineralization of uniform gallium oxide rods with cellular compatibility.
Monodispersed single crystalline alpha-GaOOH rods coated by silk fibroin (SF) have been prepared via a facile biomineralization process in the template of SF peptide. The carbon-coated alpha-Ga(2)O(3) and beta-Ga(2)O(3) rods are obtained by thermal treatment of the alpha-GaOOH rods at 600 and 800 degrees C, respectively. In vitro cytotoxicity studies of these gallium oxide rods showed no significant effect leading to restraint of cell proliferation of L929, Hela, and HaCat cells in less than 0.1 mg/mL prepared rods. On the basis of their excellent luminescence emission properties and cellular compatibilities, possible applications for bio-optoelectronic devices can be envisioned.
Yan
Danhong
D
College of Materials Science and Engineering, Sichuan University, Chengdu, 610065, China.
Yin
Guangfu
G
Huang
Zhongbing
Z
Liao
Xiaoming
X
Kang
Yunqing
Y
Yao
Yadong
Y
Hao
Baoqing
B
Gu
Jianwen
J
Han
Dong
D
D000818:Animals; D012831:Bombyx / Q000737:chemistry; D002460:Cell Line; D002470:Cell Survival; D003460:Crystallization; D005349:Fibroins / Q000737:chemistry*; D005708:Gallium / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D010455:Peptides / Q000737:chemistry; D047011:Silk / Q000737:chemistry; D013696:Temperature
D010455:Peptides; D047011:Silk; C038863:gallium oxide; D005349:Fibroins; D005708:Gallium