[Comparison of 2-octyl cyanoacrylate adhesive and suturing for wound closure in the canine small bowel model].
OBJECTIVE
We undertook this study to evaluate 2-octyl cyanoacrylate (2OCA) glue and suture for wound closure in the small bowel.


METHODS
This was a comparative and experimental study. Male and female domestic dogs (n = 10) underwent a 2.0-cm small bowel closure of two wounds. All of these had closure with 2OCA in the first wound. The controls (second wound in the same dog) were closed with suture. Four weeks later the wounds were observed to evaluate the repair.


RESULTS
Wound closure time and macrophage count were lower with the 2OCA glue than in the suture group.


CONCLUSIONS
2OCA glue has the strength to seal a small bowel wound. The inflammatory response to the glue is less than that of the suture at 4 weeks. These properties may make it a suitable material for replacing suture in a small bowel wound.
Escalante-Piña
Oscar
O
Departamento de Anatomía Humana y Laboratorio de Adiestramiento e Investigación Quirúrgica, Escuela Médico Militar, México, D. F., Mexico. coep67@hotmail.com
García-Nieto
Gabriela
G
Hernández-Jasso
Alma Rocío
AR
Reyes-Castellanos
Liliana
L
Flores-Aragón
Mariana
M
Rivera-Cruz
Jose María
JM
D000818:Animals; D003487:Cyanoacrylates; D004285:Dogs; D005260:Female; D007421:Intestine, Small / Q000601:surgery*; D008297:Male; D013536:Suture Techniques; D014014:Tissue Adhesives; D014945:Wound Healing
D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate