Role of serotoninergic system in the development of gastrointestinal diseases.
Experimental gastroduodenal ulcer was simulated after pre-injection of serotonin; gastroesophageal reflux disease and duodenogastral reflux were induced. Activation of the serotoninergic system promoted the development of alteration processes in gastroduodenal ulcer.
Lychkova
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AE
Institute of Gastroenterology, Moscow, Russia. lychkova@mail.ru
D019342:Acetic Acid / Q000494:pharmacology; D000818:Animals; D004383:Duodenogastric Reflux / Q000139:chemically induced / Q000473:pathology; D004947:Esophagus / Q000187:drug effects / Q000473:pathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000139:chemically induced / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008751:Methylene Blue / Q000494:pharmacology; D010437:Peptic Ulcer / Q000139:chemically induced / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000378:metabolism* / Q000502:physiology; D017366:Serotonin Receptor Agonists / Q000494:pharmacology; D018170:Sumatriptan / Q000494:pharmacology
D017366:Serotonin Receptor Agonists; D012701:Serotonin; D018170:Sumatriptan; D019342:Acetic Acid; D008751:Methylene Blue