Palliative radiotherapy for the skin metastasis of ovarian cancer: a case report and review of the literature.
Ovarian cancer which is the most common cause of death among all gynecological malignancies tends to metastasize through peritoneal cavity. Skin metastasis, however, is a very rare clinical entity and related with poor prognosis. We report a 43-year-old patient with recurrent ovarian cancer presented with extensive abdominal skin metastasis approximately 6 years after the initial diagnosis. Patient was treated with radiotherapy with electrons to a total dose of 37.5 Gy given in 2.5 Gy per fraction per day. Skin metastasis showed good response to radiotherapy, and the patient has been alive for 7 months after radiotherapy with no recurrences on abdominal skin. Radiotherapy might be considered as an efficient palliative treatment option for the skin metastasis of ovarian cancer.
Demirci
Senem
S
Department of Radiation Oncology, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Turkey. senem.demirci@ege.edu.tr
Yavas
Fatma
F
Ozsaran
Zeynep
Z
Ozsaran
Aydin
A
Dikmen
Yilmaz
Y
Zekioglu
Osman
O
Karabulut
Bulent
B
Aras
Arif B
AB
D000328:Adult; D003131:Combined Modality Therapy; D018283:Cystadenocarcinoma, Papillary / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000209:etiology; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010166:Palliative Care; D011855:Radiodermatitis / Q000209:etiology; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D012878:Skin Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D013684:Telangiectasis / Q000209:etiology