Behaviorally relevant burst coding in primary sensory neurons.
Bursts of action potentials in sensory interneurons are believed to signal the occurrence of particularly salient stimulus features. Previous work showed that bursts in an identified, ultrasound-tuned interneuron (AN2) of the cricket Teleogryllus oceanicus code for conspicuous increases in amplitude of an ultrasound stimulus, resulting in behavioral responses that are interpreted as avoidance of echolocating bats. We show that the primary sensory neurons that inform AN2 about high-frequency acoustic stimuli also produce bursts. As is the case for AN2, bursts in sensory neurons perform better as feature detectors than isolated, nonburst, spikes. Bursting is temporally correlated between sensory neurons, suggesting that on occurrence of a salient stimulus feature, AN2 will receive strong synaptic input in the form of coincident bursts, from several sensory neurons, and that this might result in bursting in AN2. Our results show that an important feature of the temporal structure of interneuron spike trains can be established at the earliest possible level of sensory processing, i.e., that of the primary sensory neuron.
Sabourin
Patrick
P
Department of Biology, McGill University, Montreal, Quebec H3A1B1, Canada.
Pollack
Gerald S
GS
D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D001522:Behavior, Animal; D005260:Female; D017952:Ganglia, Invertebrate / Q000502:physiology*; D006135:Gryllidae / Q000502:physiology*; D006309:Hearing / Q000502:physiology*; D007395:Interneurons / Q000502:physiology; D018408:Patch-Clamp Techniques; D011336:Probability; D011984:Sensory Receptor Cells / Q000502:physiology*; D013997:Time Factors; D014465:Ultrasonics