title: Hetero-Diels-Alder reactions of cyclic ketone derived enamide. A new and efficient concept for the asymmetric Robinson annulation.
abstract: Chiral enamides, easily prepared in one step from a cyclic ketone and an oxazolidinone, are successfully employed in high-yielding, endo, and facially selective Hetero-Diels-Alder reactions involving activated oxadienes and Siever's reagent as catalyst. From the resulting bicyclic heteroadducts, a novel and efficient asymmetric modification for the Robinson annulation of cyclic monoketones is described.
authors.affiliation: UCO2M UMR 6011 & FR 2575 CNRS, Universite du Maine, 72085, Le Mans, France.
authors.forename: Florian
authors.initials: F
authors.lastname: Gallier
authors.forename: Hidayat
authors.initials: H
authors.lastname: Hussain
authors.forename: Arnaud
authors.initials: A
authors.lastname: Martel
authors.forename: Andreas
authors.initials: A
authors.lastname: Kirschning
authors.forename: Gilles
authors.initials: G
authors.lastname: Dujardin