title: [Case of Legionella pneumonia caused by a household humidifier].
abstract: A 60-year-old-man with diabetes mellitus was admitted to our hospital because of pyrexia of up to 40 degrees and dyspnea. Chest radiograph revealed ground glass infiltrates in both lung fields. Legionella pneumonia was diagnosed as a consequence of the urinary examination performed for Legionella antigen detection; further, we initiated intravenous pazufloxacin administration. Despite an antibiotic, sivelestat sodium, and mechanical ventilation, the condition of the patient worsened and he died of respiratory failure 5 days following admission. Pulse-field gel electrophoresis (PFGE) was performed to investigate the route of infection: this technique was applied to patient sputum samples and water from the humidifier in the room of the patient. The same DNA pattern as Legionella pneumophilla serogroup 1 was identified via analysis with PFGE.
authors.affiliation: Kido Hospital.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Endo
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Ito
mesh_terms: D016521:Electrophoresis, Gel, Pulsed-Field; D004866:Equipment Contamination; D004864:Equipment and Supplies / Q000009:adverse effects* / Q000382:microbiology*; D017809:Fatal Outcome; D006794:Household Articles; D006801:Humans; D006813:Humidity; D016952:Legionella pneumophila / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000382:microbiology; D012703:Serotyping; D014871:Water Microbiology