title: [Radiation recall dermatitis after oral cyclophosphamide].
abstract: Radiation recall dermatitis is an inflammatory skin reaction occurring in a previously irradiated field following the delivery of a promoting agent. It has been described after a number of antineoplastic agents such as gemcitabine, taxanes, anthracyclines. We report the case of a 50-year-old man with metastatic prostate cancer who developed two consecutive radiation recall dermatitis episodes triggered by oral cyclophosphamide. They occurred 4 to 5 weeks after palliative radiotherapy on bone metastasis. Spontaneous resolution was observed within 6 weeks after discontinuation of cyclophosphamide and with local supportive care. To our knowledge this is the first reported case of radiation recall dermatitis after oral cyclophosphamide.
authors.affiliation: Service de Radiothérapie, CHU de Liège, Belgique.
authors.forename: C
authors.initials: C
authors.lastname: Mievis
authors.forename: N
authors.initials: N
authors.lastname: Jansen
authors.forename: F
authors.initials: F
authors.lastname: Schleich
authors.forename: C
authors.initials: C
authors.lastname: Gennigens
authors.forename: A
authors.initials: A
authors.lastname: Rorive
authors.forename: G
authors.initials: G
authors.lastname: Jérusalem
authors.forename: G
authors.initials: G
authors.lastname: Fillet
authors.forename: B
authors.initials: B
authors.lastname: Sautois
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary / Q000628:therapy*; D000284:Administration, Oral; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary / Q000628:therapy*; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*; D011855:Radiodermatitis / Q000139:chemically induced* / Q000209:etiology; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide