Effect of delta-sleep-inducing peptide on expression of heat shock protein 70 kDa in K562 cells.
For evaluation of the stress-protective influence of delta-sleep inducing peptide we studied its effects on the system of heat-shock proteins in immune cells using the method of flow cytometry. The peptide affected the expression of heat-shock protein 70 kDa in cultured human myeloleukemia K562 cells. Delta-sleep-inducing peptide reduces accumulation of intracellular heat shock proteins 70 kDa in cells cultured under conditions of high density.
Nurbakov
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AA
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia. imikha@ibch.ru
Mikhaleva
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II
Sapozhnikov
A M
AM
D017209:Apoptosis; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D005434:Flow Cytometry; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D020014:K562 Cells
D018840:HSP70 Heat-Shock Proteins; D003701:Delta Sleep-Inducing Peptide