title: [Case of allergic bronchopulmonary aspergillosis complicated with lung abscess which developed into a bronchopleural fistula].
abstract: We report a case of bronchopleural fistula in a patient with allergic bronchopulmonary aspergillosis. A 25-year-old man was admitted with high fever and chest pain. Although his chest CT in a previous hospital showed pulmonary infiltrate suggesting the existence of a mucous plug, a mass shadow in the right upper lobe was recognized on admission to our hospital. Based on the presence of eosinophilia, elevated levels of total IgE and Aspergillus-specific IgE, positive precipitating antibody to Aspergillus, and detection of A. fumigatus in bronchial washing fluid, we diagnosed this case as ABPA complicated with lung abscess. Although we treated by antibiotics and antifungal drugs, the lung abscess did not improve and led to bronchopleural fistula. After addition of nebulised liposomal amphotericin B, his symptoms improved and treatment was successful.
authors.affiliation: Department of Medicine, Teikyo University School of Medicine.
authors.forename: Asae
authors.initials: A
authors.lastname: Hara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nagase
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Hayashi
authors.forename: Michio
authors.initials: M
authors.lastname: Kuramochi
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Ishida
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Adachi
authors.forename: Naohito
authors.initials: N
authors.lastname: Suzuki
authors.forename: Ken
authors.initials: K
authors.lastname: Ohta
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001983:Bronchial Fistula / Q000209:etiology*; D005402:Fistula / Q000209:etiology*; D006801:Humans; D008081:Liposomes; D008169:Lung Abscess / Q000209:etiology* / Q000628:therapy; D008297:Male; D010995:Pleural Diseases / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D008081:Liposomes; D000666:Amphotericin B