title: Incidence of osteonecrosis from histopathological study following fracture neck of femur.
abstract: This prospective study was aimed to evaluate the incidence of osteonecrosis in Thai patients with fracture neck of femur Forty-three patients who had sustained fracture were enrolled in the present study. The overall incidence of osteonecrosis was 72.1%. Incidence of osteonecrosis was 53.3% among patients who underwent surgery within 1 week after injury and 82.1% among those who underwent surgery after that time but there was no statistical difference (p-value = 0.07. Regarding displacement of fracture, the present study found the incidence of osteonecrosis was 100% among patients with undisplaced (Garden type 1 and 2) fractures and 60.0% and 76.9%, respectively among those with displaced fractures (Garden type 3 and 4). Most histological changes according to Ficat and Arlet Method of undisplaced fractures were stage 1 and 2 and the displaced fracture was stage 2. It reveals a high rate of osteonecrosis following fracture neck of femur but mostly in early reversible change. There was no significant statistical difference regarding age, duration, type of fracture, and co-morbidity.
authors.affiliation: Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. voranewt@yahoo.com
authors.forename: Voranuch
authors.initials: V
authors.lastname: Thanakit
authors.forename: Ugyen
authors.initials: U
authors.lastname: Thinley
authors.forename: Kiat
authors.initials: K
authors.lastname: Witoonchart
authors.forename: Phairat
authors.initials: P
authors.lastname: Thuvasethakul
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016001:Confidence Intervals; D005260:Female; D005265:Femoral Neck Fractures / Q000150:complications*; D005271:Femur Head Necrosis / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology