title: [Oral insulin preparations for the regulation of the glucose level in the blood].
abstract: Oral administration of diluted solutions of insulin results in the absorption of the hormone into bloodstream. After oral administration of diluted insulin solutions to healthy volunteers and animals with experimental diabetes insulin does not undergo hydrolytic degradation under the action of proteolytic enzymes and its absorption is sufficient to produce the hypoglycemic effect. This approach gives a chance of creating of novel strategy for diabetes treatment.
authors.forename: L I
authors.initials: LI
authors.lastname: Valuev
authors.forename: G A
authors.initials: GA
authors.lastname: Sytov
authors.forename: L K
authors.initials: LK
authors.lastname: Starosel'tseva
authors.forename: I L
authors.initials: IL
authors.lastname: Valuev
authors.forename: L V
authors.initials: LV
authors.lastname: Vanchugova
authors.forename: T A
authors.initials: TA
authors.lastname: Valueva
authors.forename: M V
authors.initials: MV
authors.lastname: Ul'ianova
authors.forename: N A
authors.initials: NA
authors.lastname: Platé
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin