title: A case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma.
abstract: We report a case of hepatic angiomyolipoma with uncommon clinical features. A 56-year-old man presented with a hepatic tumor in the caudate lobe. The tumor was hypoechoic on ultrasonography, showed early-phase hyperattenuation on enhanced computed tomography and did not absorb iron on superparamagnetic iron oxide-enhanced magnetic resonance imaging. Hepatocellular carcinoma was highly suspected, and the patient underwent hepatic resection. Histologically, the tumor was mainly composed of smooth muscle cells and contained small amounts of adipose cells and blood vessels. On immunohistochemical staining, the smooth muscle cells were positive for a melanocytic cell-specific monoclonal antibody. In cases with uncommon features of angiomyolipoma, it is quite difficult to distinguish angiomyolipoma from hepatocellular carcinoma.
authors.affiliation: Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takahara
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kawai
authors.forename: Eisuke
authors.initials: E
authors.lastname: Kaji
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Toyokawa
authors.forename: Morihito
authors.initials: M
authors.lastname: Nakatsu
authors.forename: Masaharu
authors.initials: M
authors.lastname: Ando
authors.forename: Mamoru
authors.initials: M
authors.lastname: Hirohata
mesh_terms: D018207:Angiomyolipoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D014408:Biomarkers, Tumor / Q000378:metabolism; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor