[Poorly differentiated prostate cancer may be associated with cytomegalovirus infection in prostatic tissue].
Polymerase chain-reaction procedure was used to test archival samples of prostate tissue from 90 cancer patients for cytomegalovirus infection detected in 46.7%. The median Gleason score and G-index (TNM classification) were significantly higher in CMV-positive patients (8 and 4, respectively) than those in CMV-negative ones (6 and 2, respectively). A relationship between cytomegalovirus infection and poor prognosis of prostate cancer is suggested.
Andabekov
T T
TT
Klochkova
T G
TG
Urbanskiĭ
A I
AI
Samsonov
R B
RB
Shkol'nik
M I
MI
Evtushenko
V I
VI
Karelin
M I
MI
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003586:Cytomegalovirus Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000821:virology*; D012720:Severity of Illness Index
D014408:Biomarkers, Tumor