Advances in dengue vaccine development.
Dengue viruses are the most important arboviruses causing human disease. Expansion of the disease in recent decades to include more geographical areas of the world, an appreciation of the disease burden and market potentials have spurred a flurry of activity in the development of vaccines to combat dengue viruses. Recent progress in this area and some of the obstacles associated with this development are discussed.
Raviprakash
Kanakatte
K
Naval Medical Research Center, Silver Spring, MD, USA. Kanakatte.raviprakas@med.navy.mil
Defang
Gabriel
G
Burgess
Timothy
T
Porter
Kevin
K
D000818:Animals; D002986:Clinical Trials as Topic; D003715:Dengue / Q000276:immunology* / Q000517:prevention & control*; D053059:Dengue Vaccines / Q000008:administration & dosage / Q000276:immunology*; D003716:Dengue Virus / Q000235:genetics / Q000276:immunology*; D006801:Humans; D014330:Tropical Medicine / Q000639:trends*; D014611:Vaccination; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000276:immunology; D022223:Vaccines, Subunit / Q000008:administration & dosage / Q000276:immunology
D053059:Dengue Vaccines; D019444:Vaccines, DNA; D022223:Vaccines, Subunit