Fungal mechanisms for host iron acquisition.
The iron scarcity in the host environment presents a challenge for infecting microorganisms. Fungi can assimilate iron via reductive, nonreductive, and host molecule-specific mechanisms. Recent developments in the characterization of iron acquisition mechanisms in the four best-studied fungal pathogens reveal commonalities and differences in those mechanisms as well as in their regulatory pathways.
Kornitzer
Daniel
D
Department of Molecular Microbiology, B. Rappaport Faculty of Medicine, Technion-IIT, Haifa, Israel. danielk@tx.technion.ac.il
D000818:Animals; D005658:Fungi / Q000378:metabolism*; D054884:Host-Pathogen Interactions; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008954:Models, Biological
D007501:Iron