title: Early detection of lesions of dorsal artery of foot in patients with type 2 diabetes mellitus by high-frequency ultrasonography.
abstract: This study evaluated the value of high-frequency ultrasonograpy for early detection of dorsal artery of foot in patients with type 2 diabetes mellitus (MD). Eighty subjects including 40 patients with type 2 MD (T2DM group) and 40 healthy volunteers (NC group) were recruited. The intima-media thickness (IMT), the inner diameter and the perfusion of dorsal artery of foot were measured by using high-frequency ultrasonograpy. Meanwhile, the parameters of vascular elasticity, including stiffness parameter (beta), pressure-strain elastic modulus (Erho), arterial compliance (AC), augment index (AI), and pulse wave conducting velocity (PWVbeta) were detected by means of echo-tracking technique. The results showed that no significant difference was found in the IMT, systolic diameter (Ds), diastolic diameter (Dd) and peak systolic velocity (PSV) between T2DM and NC groups. Erho and PWVbeta were increased, and AC was decreased in T2DM group as compared with those in NC group with the differences being significant (P<0.05 for all). There was no significant difference in beta and AI between T2DM and NC groups. It was concluded that high-frequency ultrasonography in combination with echo-tracking technique is sensitive and non-invasive, and can be used for early detection of sclerosis of the lower extremity artery in patients with type 2 MD.
authors.affiliation: Department of Medical Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. zhyr008@yahoo.com.cn
authors.forename: Yanrong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wenjing
authors.initials: W
authors.lastname: Li
authors.forename: Tianwei
authors.initials: T
authors.lastname: Yan
authors.forename: Chengfa
authors.initials: C
authors.lastname: Lu
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Huang
mesh_terms: D000328:Adult; D001158:Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000209:etiology; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging*; D003925:Diabetic Angiopathies / Q000000981:diagnostic imaging*; D042241:Early Diagnosis; D004548:Elasticity; D005260:Female; D005528:Foot / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D017539:Tunica Intima / Q000000981:diagnostic imaging; D014463:Ultrasonography; D055815:Young Adult