Dietary intervention to lower serum cholesterol.
BACKGROUND
Dietary intervention to lower serum LDL-cholesterol (LDL-C) is effective, yet underutilised in general practice.


OBJECTIVE
This report summarises the findings of an expert roundtable convened to review the evidence relating to dietary interventions to lower serum LDL-C.


CONCLUSIONS
Interventions that lower LDL-C lower the risk of cardiovascular disease. Comprehensive dietary intervention is indicated in all patients with an absolute 5 year risk for coronary disease of 10% or greater. Short term trials indicate that these interventions have the potential to lower LDL-C by approximately 20%. A year long trial has shown mean LDL-C lowering of 13%, with about one-third of subjects achieving a reduction greater than 20%, highlighting the importance of adherence to dietary advice. The most effective dietary strategies are replacing saturated and trans fatty acids with poly- and monounsaturated fats and increasing intake of plant sterols. Losing weight and increasing soluble fibre and soy protein intake can also lower serum cholesterol and may be considered when recommending a nutritionally balanced, cholesterol lowering diet. Motivational interviewing by general practitioners can improve the effectiveness of brief, behaviour orientated advice and dietary counselling to lower serum cholesterol.
Clifton
Peter
P
CSIRO Division of Human Nutrition, Adelaide, South Australia. peter.clifton@csiro.au
Colquhoun
David
D
Hewat
Claire
C
Jones
Peter
P
Litt
John
J
Noakes
Manny
M
O'Brien
Richard
R
Shrapnel
Bill
B
Skeaff
Murray
M
D002318:Cardiovascular Diseases / Q000517:prevention & control; D008078:Cholesterol, LDL / Q000097:blood*; D003376:Counseling; D005194:Family Practice; D006801:Humans; D006937:Hypercholesterolemia / Q000178:diet therapy*
D008078:Cholesterol, LDL