Structural and functional similarities between two bacterial chromosome compacting machineries.
Chromosomes are condensed in all forms of life. SMC-based condensins are the key mediators in this process, but their molecular mechanisms remain elusive. Two different condensin complexes have been identified in prokaryotic organisms: MukB-MukE-MukF and SMC-ScpA-ScpB. This review focuses on comparison between the two machineries based on structural, biochemical and other related information in the light of their structure and function.
Lim
Jae-Hong
JH
Beamline division, Pohang Accelerator Laboratory, Pohang, Kyungbuk 790-784, Republic of Korea.
Oh
Byung-Ha
BH
D000251:Adenosine Triphosphatases / Q000737:chemistry / Q000378:metabolism*; D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000737:chemistry / Q000378:metabolism*; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism*; D008969:Molecular Sequence Data; D046912:Multiprotein Complexes / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation
D001426:Bacterial Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D046912:Multiprotein Complexes; C118650:SMC protein, Bacteria; C108312:condensin complexes; D000251:Adenosine Triphosphatases