title: Kinetic resolution of racemic 1-alkyl-2-methylenecyclopropanes via palladium-catalyzed silaborative C-C cleavage.
abstract: Kinetic resolution of racemic 1-alkyl-2-methylenecyclopropanes via silaborative C-C cleavage was efficiently catalyzed by a palladium complex bearing a chiral phosphoramidite, affording 2-boryl-3-silylmethyl-1-alkenes as major products with up to 92% ee. Enantioenrichment through parallel kinetic resolution, where the slower reacting enantiomer was converted to the constitutional isomer of the major product, may be involved as the crucial stereodiscriminating step.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, Japan.
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Ohmura
authors.forename: Hiroki
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Michinori
authors.initials: M
authors.lastname: Suginome