Endoscopic topical application of Ankaferd Blood Stopper for neoplastic gastrointestinal bleeding: A retrospective analysis.
OBJECTIVE
The aim of this study was to retrospectively assess the haemostatic efficacy of the endoscopic topical use of Ankaferd Blood Stopper (ABS) in the setting of neoplastic GI bleeding.


METHODS
The records of 10 patients with neoplastic GI bleeding (7 gastric, 3 rectal) were evaluated retrospectively. Written informed consent regarding the off-label use of ABS as a means of attaining haemostasis had been obtained from all of the patients prior to the procedure. In all patients, ABS was applied topically. Rates of bleeding control and post-procedural complications were documented.


RESULTS
Haemostasis was achieved in all patients within seconds of endoscopic application of ABS, with no immediate complications. Seven patients underwent subsequent cancer surgery after a bleeding-free post-procedural period.


CONCLUSIONS
ABS as a novel haemostatic agent could have a potential benefit in controlling bleeding from GI tumours. Prospective controlled studies are needed to help establish its efficacy, and perhaps offer a comparison to conventional haemostatic interventions.
Kurt
Mevlut
M
Department of Gastroenterology, Turkiye Yuksek Ihtisas Teaching and Research Hospital, Sihhiye, Ankara, Turkey. dr.mevlutkurt@gmail.com
Akdogan
Meral
M
Onal
Ibrahim Koral
IK
Kekilli
Murat
M
Arhan
Mehmet
M
Shorbagi
Ali
A
Aksu
Salih
S
Kurt
Ozlem Kar
OK
Haznedaroglu
Ibrahim Celalettin
IC
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000209:etiology*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D056687:Off-Label Use; D010936:Plant Extracts / Q000008:administration & dosage*; D012004:Rectal Neoplasms / Q000150:complications*; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000150:complications*
D006490:Hemostatics; D010936:Plant Extracts; C539751:ankaferd blood stopper