[Quantitative repolarization indices in diagnosis of left ventricular hypertrophy in hypertensive patients].
OBJECTIVE
To determine informative value of quantitative parameters of orthogonal ECG repolarization phase in diagnosis of left ventricular hypertrophy (LVH) in hypertensive patients.


METHODS
A total of 210 healthy subjects and 241 hypertensive patients with LVH (LV myocardium mass index > 125 g/m2 in males and > 110 g/m2 in women) comprised two groups--control and test. The study was made of quantitative parameters (components X, Y, Z, modules and angles of azimuth and elevation) of wave T integral vector, wave T maximal vector, ST vector, ventricular gradient; spatial and projection areas of wave T, the angle between integral vectors of spatial waves QRS and T (phi angle).


RESULTS
The test group had reduced X, Y components and elevated vectors, their azimuth and phi angle. Most informative for repolarization were components X of T maximal and integral vectors being as informative as Rx+Sz and Cornel product. The method of multiple regression analysis was used to plot discriminant function taking account of most informative indices of depolarization and repolarization--Rx+Sz and X component of T maximal vector. The area under ROC curve for this function was greater than for the variables alone and Cornel product in both groups (0.90 +/- 0.02 and 0.86 +/- 0.02, p < 0.05 for the control and test group, respectively).


CONCLUSIONS
Quantitative parameters of repolarization phase can improve LVG diagnosis in hypertensive patients.
Sakhnova
T A
TA
Blinova
E V
EV
Sergakova
L M
LM
Ataullakhanova
D M
DM
Chazova
I E
IE
D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009929:Organ Size / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D016277:Ventricular Function, Left / Q000502:physiology*