title: Effect of surfactants on the thermal, conformational and rheological properties of collagen.
abstract: Collagen is an important biomaterial and its interaction with surfactant is important in light of its use in various cosmetics and dermatological applications. Presently, the effect of surfactants on the physico-chemical properties of collagen has been studied. The thermal stability of collagen is reduced by sodium dodecyl sulfate and hexadecyltrimethylammmonium bromide, whereas Triton X-100 does not. The viscosity of collagen is influenced greatly depending on the surfactant concentrations. The secondary structure of collagen shows changes only in the molar ellipticity. The role of charge and concentration of surfactants in influencing the various physico-chemical properties of collagen has been elucidated.
authors.affiliation: Chemical Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Sardar Patel Road, Adyar, Chennai-60002, India. nishad.naveed@gmail.com
authors.forename: N Nishad
authors.initials: NN
authors.lastname: Fathima
authors.forename: Aruna
authors.initials: A
authors.lastname: Dhathathreyan
mesh_terms: D000818:Animals; D002152:Calorimetry, Differential Scanning; D002942:Circular Dichroism; D003094:Collagen / Q000737:chemistry*; D011487:Protein Conformation / Q000187:drug effects; D011489:Protein Denaturation / Q000187:drug effects; D051381:Rats; D012212:Rheology / Q000187:drug effects; D013501:Surface-Active Agents / Q000737:chemistry* / Q000494:pharmacology; D013696:Temperature; D014783:Viscosity / Q000187:drug effects
chemical_list: D013501:Surface-Active Agents; D003094:Collagen