title: [Two cases of lung injury due to inhalation of waterproofing spray--with special reference to pulmonary function disorder].
abstract: CASE 1: A 57-year-old man experienced severe dyspnea 24 hours after inhalation of waterproofing spray. Computed tomography (CT) revealed diffuse ground glass opacities in bilateral lungs. Pulmonary function tests showed mixed ventilatory disturbance with a low expiratory flow rate near the end of forced expiration and a normal diffusing capacity with normal functional residual capasity. The pulmonary function disorder was quickly improved by steroid therapy. CASE 2: A 59-year-old man smoked after inhaling waterproofing spray and soon developed dyspnea. The findings of CT were similar to those of case 1. His pulmonary function test revealed restrictive ventilatory disturbance and normal pulmonary diffusing capacity with low functional residual capacity. These findings improved without steroid treatment. However, it took more time for the pulmonary function to recover. There was probably specific inflammation around bronchioles, and the inflammation might have spread to the alveolar region in such cases with severe pulmonary function disorder. Steroid treatment seems to be useful to improve both the pulmonary function disorder and the clinical feature due to inhalation of waterproofing spray.
authors.affiliation: Department of Respiratory Disease, Hiroshima Red Cross Hospital.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Arita
authors.forename: Toshiki
authors.initials: T
authors.lastname: Kajihara
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nitta
authors.forename: Akiko
authors.initials: A
authors.lastname: Mito
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Awaya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamasaki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ohashi
mesh_terms: D055371:Acute Lung Injury / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D000336:Aerosols; D001988:Bronchiolitis / Q000139:chemically induced; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000009:adverse effects*; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed
chemical_list: D000336:Aerosols; D011138:Polytetrafluoroethylene