title: A case of cerebral erdheim-chester disease with progressive cerebellar syndrome.
abstract: Erdheim-Chester disease (ECD) is a rare non-Langerhans form of histiocytosis. Cerebellar involvement is rare in this syndrome. We report a 37-year-old woman with slowly progressive cerebellar ataxia, dysmetria of limbs, nystagmus, and dysarthria, bilateral painful axillary masses, and generalized arthralgia. Brain MRI revealed cerebellar atrophy with focal lesions in the pons, middle cerebellar peduncle, and the cerebellum. She underwent incisional biopsy of her axillary masses which showed findings consistent with ECD. An MRI of her lower extremities revealed lesions in the diaphyses, metaphyses, and epiphyses of the proximal tibia and distal femur bilaterally. This is a rare case of cerebral ECD with progressive cerebellar syndrome associated with cerebellar atrophy.
authors.affiliation: Department of Neurology, Konyang University College of Medicine, Daejeon, Korea.
authors.forename: Sang-Jun
authors.initials: SJ
authors.lastname: Na
authors.forename: Kee Ook
authors.initials: KO
authors.lastname: Lee
authors.forename: Jung Eun
authors.initials: JE
authors.lastname: Kim
authors.forename: Yong-Duk
authors.initials: YD
authors.lastname: Kim