Recent advances in the development of polyamine analogues as antitumor agents.
Casero
Robert A
RA
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland 21231, USA.
Woster
Patrick M
PM
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D015317:Biogenic Polyamines / Q000502:physiology; D001943:Breast Neoplasms / Q000188:drug therapy; D004247:DNA / Q000378:metabolism; D055808:Drug Discovery; D000518:Eflornithine / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D056572:Histone Deacetylase Inhibitors; D056466:Histone Demethylases; D006706:Homeostasis; D006801:Humans; D010089:Oxidoreductases, N-Demethylating / Q000037:antagonists & inhibitors; D011073:Polyamines / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D015317:Biogenic Polyamines; D004791:Enzyme Inhibitors; D056572:Histone Deacetylase Inhibitors; D011073:Polyamines; D004247:DNA; D056466:Histone Demethylases; C495195:KDM1A protein, human; D010089:Oxidoreductases, N-Demethylating; D000518:Eflornithine