title: Renal tumors in the second decade of life: results from the California Cancer Registry.
abstract: BACKGROUND
  Renal tumors are rare in adolescents and young adults. The aim of this study was to characterize the histologic condition, epidemiology, and survival of renal tumors in patients aged 11 to 20 years old using a large, population-based database.
  
  
  METHODS
  The California Cancer Registry was reviewed from the years 1988 to 2004. All renal tumors in patients aged 11 to 20 years old were identified. The data were analyzed with relation to patient age, sex and ethnicity, tumor histologic examination, and actuarial mortality rates.
  
  
  RESULTS
  Seventy-seven primary renal malignancies were identified. Thirty-nine (51%) were renal cell carcinoma, 23 (30%) were Wilms' tumor, and 15 (20%) were other tumor types. The mean age of the patients with renal cell carcinoma was 16.7 years old, which was significantly older than the Wilms' tumor patients (13.9 years; P < .01). The 5-year cumulative survival rate of patients with renal cell carcinoma was 54%, which was worse than that of Wilms' tumor patients (77%).
  
  
  CONCLUSIONS
  Primary renal malignancies are uncommon in the second decade of life. The most common tumor type in this age-group is renal cell carcinoma followed by Wilms' tumor. Patients with renal cell carcinoma tend to be older and have a lower survival than patients with other kidney tumors.
authors.affiliation: Department of Surgery, University of California at San Diego, San Diego, CA 92013, USA. alipskar@nshs.edu
authors.forename: Julia
authors.initials: J
authors.lastname: Grabowski
authors.forename: Jonathan
authors.initials: J
authors.lastname: Silberstein
authors.forename: Sidney L
authors.initials: SL
authors.lastname: Saltzstein
authors.forename: Nicholas
authors.initials: N
authors.lastname: Saenz
mesh_terms: D000293:Adolescent; D002140:California / Q000453:epidemiology; D002292:Carcinoma, Renal Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000453:epidemiology*; D008297:Male; D012042:Registries; D016019:Survival Analysis; D009396:Wilms Tumor / Q000453:epidemiology*; D055815:Young Adult