title: High transmissibility of the modern Beijing Mycobacterium tuberculosis in homeless patients of Japan.
abstract: A population-based study of Mycobacterium tuberculosis isolated from homeless tuberculosis patients was performed during 2002-2004 in Osaka City, Japan. The data show that the ancient Beijing subfamily was predominant, whereas clustered isolates based on refined variable number of tandem repeats genotyping (19 loci) mainly belonged to the modern Beijing subfamily, suggesting its increased transmissibility.
authors.affiliation: Department of Microbiology, Osaka City Institute of Public Health and Environmental Sciences, 8-34 Tojo-cho, Tennoji-ku, Osaka 543-0026, Japan. taka-wada@city.osaka.lg.jp
authors.forename: Takayuki
authors.initials: T
authors.lastname: Wada
authors.forename: Sami
authors.initials: S
authors.lastname: Fujihara
authors.forename: Akira
authors.initials: A
authors.lastname: Shimouchi
authors.forename: Makoto
authors.initials: M
authors.lastname: Harada
authors.forename: Hisashi
authors.initials: H
authors.lastname: Ogura
authors.forename: Sohkichi
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hase
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015373:Bacterial Typing Techniques / Q000379:methods; D016000:Cluster Analysis; D005260:Female; D005838:Genotype; D006703:Ill-Housed Persons; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D013045:Species Specificity; D020080:Tandem Repeat Sequences; D014376:Tuberculosis / Q000382:microbiology* / Q000635:transmission*