Natural and unnatural ribozymes: back to the primordial RNA world.
We review natural and in vitro selected ribozymes, for which combined studies could provide us with both insight into the functions performed by ancient RNA molecules in a primitive RNA world and a hypothesis about evolutionary steps that led to the contemporary world.
Talini
Giulia
G
Department of Astronomy and Space Science, University of Florence, Largo E. Fermi 2, 50125 Florence, Italy. giulia.talini@unifi.it
Gallori
Enzo
E
Maurel
Marie-Christine
MC
D019020:Directed Molecular Evolution; D019418:Evolution, Chemical; D012313:RNA / Q000378:metabolism*; D016337:RNA, Catalytic / Q000378:metabolism*
D016337:RNA, Catalytic; D012313:RNA