De novo dedifferentiated chordoma of the sacrum: a case report and review of the literature.
Dedifferentiated chordoma is a rare primary malignant bone cancer. Most cases of dedifferentiated chordoma (DC) are transformed from recurrent chordoma after surgical resection or radiation. The prognosis of DC is extremely poor because of the aggressive nature of the tumor and the potential distant metastases. We report a case of de novo DC of the sacrum in a patient without prior surgical procedure or radiation treatment. A complete review of reported cases sourced from reports published in English literature is discussed and expanded upon and conclusions on the treatment of DC are presented.
Chou
Wen-Chi
WC
Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan; Division of Oncology, Department of Internal Medicine, Saint Paul's Hospital, Taoyuan, Taiwan.
Hung
Yu-Shin
YS
Lu
Chang-Hsien
CH
Yeh
Kun-Yun
KY
Sheu
Swei-
S
Liaw
Chuang-Chi
CC
D001859:Bone Neoplasms / Q000473:pathology*; D002817:Chordoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012447:Sacrum