title: Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity.
abstract: Contents of bioactive components, free radical scavenging and anti-acne producing bacteria activities of young and mature fruit rind extracts of mangosteen were compared. The young fruit rind extract contained significantly higher contents of phenolics and tannins and promoted higher free radical scavenging activity than the mature fruit rind extract, while the later extract contained higher contents of flavonoids and alpha-mangostin xanthone and gave higher anti-acne producing bacteria activity than the young fruit rind extract. Thus, the young and mature stages of mangosteen fruit rind should be beneficial for further development of antioxidant and anti-acne pharmaceutical preparations, respectively.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
authors.forename: Werayut
authors.initials: W
authors.lastname: Pothitirat
authors.forename: Mullika Traidej
authors.initials: MT
authors.lastname: Chomnawang
authors.forename: Roongtawan
authors.initials: R
authors.lastname: Supabphol
authors.forename: Wandee
authors.initials: W
authors.lastname: Gritsanapan
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology* / Q000627:therapeutic use; D000975:Antioxidants / Q000032:analysis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D005419:Flavonoids / Q000032:analysis / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000032:analysis / Q000494:pharmacology / Q000627:therapeutic use; D005638:Fruit; D029762:Garcinia mangostana / Q000737:chemistry*; D010636:Phenols / Q000032:analysis / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013634:Tannins / Q000032:analysis / Q000494:pharmacology*; D044004:Xanthones / Q000032:analysis / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols; D010936:Plant Extracts; D013634:Tannins; D044004:Xanthones