[Monoclonal antibodies in diagnostics of high-grade gliomas].
The review is focused on the modem methods of radioimmune diagnostics of high-grade gliomas with monoclonal antibodies and other approaches of radioimmunolocalisation with pretargeted bispecific antibodies. High-grade tumor-related proteins were analysed as potential targets for radiolabeled antibodies. Recent experimental and clinical data and the most promising immunochemical approaches for diagnostic and targeted therapy of gliomas with tumor-specific antibodies are discussed.
Baklaushev
V P
VP
Pavlov
K A
KA
Chekhonin
V P
VP
D000818:Animals; D018033:Antibodies, Bispecific / Q000737:chemistry*; D003937:Diagnosis, Differential; D005910:Glioma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D011863:Radioimmunoassay / Q000379:methods
D018033:Antibodies, Bispecific