title: From global to regional: the importance of pneumococcal disease in Latin America.
abstract: Latin America is estimated to have 3637 cases of meningitis, 14,548 cases of bacteremia, 192,761-318,238 cases of pneumonia, and about 5.6 million cases of otitis media annually. Pneumococcal conjugate vaccines (PCVs) have proven to be effective in preventing paediatric pneumococcal disease. Monitoring serotypes and anti-microbial resistance in Latin American children by collecting clinical and epidemiological data at regular intervals is essential. It is important to identify and support systems for surveillance of invasive pneumococcal disease based on population to demonstrate the impact of PCVs. Surveillance should include pneumococcal disease in adults to estimate the indirect effects of the vaccine.
authors.affiliation: Albert B. Sabin Vaccine Institute (SVI), 2000 Pennsylvania Ave, NW, Suite 7100, Washington, DC 20006-4400, USA. ciro.dequadros@sabin.org
authors.forename: Ciro A
authors.initials: CA
authors.lastname: de Quadros
mesh_terms: D017281:Cost of Illness; D006801:Humans; D007843:Latin America / Q000453:epidemiology; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000008:administration & dosage; D011159:Population Surveillance; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification; D018074:Vaccines, Conjugate / Q000008:administration & dosage
chemical_list: D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate