von Willebrand factor in cadaveric urine for forensic investigation.
Preliminary experimental study of urinary von Willebrand factor (VWF) concentration was undertaken to evaluate the utility of this parameter in forensic investigations. ELISA was used to measure VWF concentration. Correlations of urinary VWF with cause of death and postmortem interval (PMI) were ascertained. As PMI advanced, urinary VWF increased but plasma VWF did not. Cause of death was not significantly correlated with VWF. This study indicated the possibility that urinalysis would be helpful to estimate PMI.
Kasuda
Shogo
S
Department of Legal Medicine, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan. skasuda@naramed-u.ac.jp
Kudo
Risa
R
Morimura
Yoshifumi
Y
Tatsumi
Kohei
K
Sakurai
Yoshihiko
Y
Shima
Midori
M
Hatake
Katsuhiko
K
D001237:Asphyxia / Q000097:blood / Q000652:urine; D002056:Burns / Q000097:blood / Q000652:urine; D002102:Cadaver; D004332:Drowning / Q000097:blood / Q000652:urine; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D008875:Middle Aged; D011180:Postmortem Changes; D014951:Wounds, Stab / Q000097:blood / Q000652:urine; D014841:von Willebrand Factor / Q000032:analysis / Q000652:urine*
D014841:von Willebrand Factor