Case report of implant placement in a patient with Paget's disease on bisphosphonate therapy.
Paget's disease is the second most common bone disease following osteoporosis. Paget's disease is characterized by abnormal resorption and deposition of bone. The most widely used agents to treat Paget's disease are bisphosphonates. Bisphosphonates have been given much attention due to reports of osteonecrosis associated with their use. This case report demonstrates the placement of implants in a patient with Paget's disease on a six-month-course of bisphosphonate therapy. The patient had post-operative complications and a secondary placement but no signs of bisphosphonate-associated osteonecrosis of the jaw (ONJ). Although complications may exist, the placement of implants in a patient with Paget's disease taking bisphosphonates can have a positive outcome.
Pirih
Flavia Q
FQ
University of Michigan School of Dentistry, USA.
Zablotsky
Mark
M
Cordell
Kitrina
K
McCauley
Laurie K
LK
D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D020878:Device Removal; D004164:Diphosphonates / Q000627:therapeutic use*; D012968:Etidronic Acid / Q000627:therapeutic use*; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D006801:Humans; D008297:Male; D016348:Osseointegration / Q000502:physiology; D010001:Osteitis Deformans / Q000188:drug therapy*; D012086:Reoperation; D013530:Surgical Wound Infection / Q000209:etiology
D050071:Bone Density Conservation Agents; D015921:Dental Implants; D004164:Diphosphonates; D012968:Etidronic Acid