title: A dual-phantom system for validation of velocity measurements in stenosis models under steady flow.
abstract: A dual-phantom system is developed for validation of velocity measurements in stenosis models. Pairs of phantoms with identical geometry and flow conditions are manufactured, one for ultrasound and one for particle image velocimetry (PIV). The PIV model is made from silicone rubber, and a new PIV fluid is made that matches the refractive index of 1.41 of silicone. Dynamic scaling was performed to correct for the increased viscosity of the PIV fluid compared with that of the ultrasound blood mimic. The degree of stenosis in the models pairs agreed to less than 1%. The velocities in the laminar flow region up to the peak velocity location agreed to within 15%, and the difference could be explained by errors in ultrasound velocity estimation. At low flow rates and in mild stenoses, good agreement was observed in the distal flow fields, excepting the maximum velocities. At high flow rates, there was considerable difference in velocities in the poststenosis flow field (maximum centreline differences of 30%), which would seem to represent real differences in hydrodynamic behavior between the two models. Sources of error included: variation of viscosity because of temperature (random error, which could account for differences of up to 7%); ultrasound velocity estimation errors (systematic errors); and geometry effects in each model, particularly because of imperfect connectors and corners (systematic errors, potentially affecting the inlet length and flow stability). The current system is best placed to investigate measurement errors in the laminar flow region rather than the poststenosis turbulent flow region.
authors.affiliation: Department of Medical Physics, University of Edinburgh, UK.
authors.forename: James R
authors.initials: JR
authors.lastname: Blake
authors.forename: William J
authors.initials: WJ
authors.lastname: Easson
authors.forename: Peter R
authors.initials: PR
authors.lastname: Hoskins
mesh_terms: D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D001783:Blood Flow Velocity; D001809:Blood Viscosity; D004867:Equipment Design; D005990:Glycerol; D018056:Hemorheology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D012031:Refractometry; D012826:Silicone Elastomers; D018608:Ultrasonography, Doppler / Q000379:methods
chemical_list: D012826:Silicone Elastomers; D005990:Glycerol