Photonic crystal fiber long-period gratings for biochemical sensing.
We present experimental results showing that long-period gratings in photonic crystal fibers can be used as sensitive biochemical sensors. A layer of biomolecules was immobilized on the sides of the holes of the photonic crystal fiber and by observing the shift in the resonant wavelength of a long-period grating it was possible to measure the thickness of the layer. The long-period gratings were inscribed in a large-mode area silica photonic crystal fiber with a CO2 laser. The thicknesses of a monolayer of poly-L-lysine and double-stranded DNA was measured using the device. We find that the grating has a sensitivity of approximately 1.4nm/1nm in terms of the shift in resonance wavelength in nm per nm thickness of biomolecule layer.
Rindorf
Lars
L
Jensen
Jesper B
JB
Dufva
Martin
M
Pedersen
Lars Hagsholm
LH
Høiby
Poul Erik
PE
Bang
Ole
O