Central nervous system lymphomatoid granulomatosis presenting with parkinsonism.
Lymphomatoid granulomatosis (LG) is a potentially malignant lymphoproliferative disorder. The lung is the most common involved site, followed by the skin and nervous system. However, LG of the central nervous system presenting with Parkinsonism is very rare. We report a patient with LG who presented with parkinsonian features such as bilateral rigidity, bradykinesia, and agitation. Brain magnetic resonance imaging showed multifocal punctuate enhanced lesions in both supra- and infratentorial areas. Steroid pulse therapy resulted in a dramatical improvement in the symptoms and MRI abnormalities.
Sohn
Eun Hee
EH
Department of Neurology, Chungnam National University, Daejeon, Korea.
Song
Chang Joon
CJ
Lee
Hyo-Jin
HJ
Kim
Samyong
S
Kim
Jae-Moon
JM
Lee
Ae Young
AY