title: Comparative study of the in vitro effect of nanoliposomes with oxidized dextrans on peritoneal cells.
abstract: We studied the in vitro effect of hybrid molecular-nanosomal biocompatible compositions on cultured peritoneal cells. The compositions consisted of oxidized dextrans with a mean molecular weight of 35 and 60 kDa, which were obtained by chemical and radiochemical oxidation of dextran. Hybrid nanoliposomal compositions of chemically oxidized dextran (permanganate method) had greater biocompatibility and tropic activity to macrophages compared to nanoliposomes of radiochemically oxidized dextran.
authors.affiliation: Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. sck@soramn.ru
authors.forename: V A
authors.initials: VA
authors.lastname: Shkurupiy
authors.forename: S A
authors.initials: SA
authors.lastname: Arkhipov
authors.forename: A V
authors.initials: AV
authors.lastname: Troitsky
authors.forename: N G
authors.initials: NG
authors.lastname: Luzgina
authors.forename: M V
authors.initials: MV
authors.lastname: Zaikovskaja
authors.forename: E P
authors.initials: EP
authors.lastname: Gulyaeva
authors.forename: T N
authors.initials: TN
authors.lastname: Bistrova
authors.forename: E G
authors.initials: EG
authors.lastname: Ufimceva
authors.forename: D A
authors.initials: DA
authors.lastname: Iljin
authors.forename: E S
authors.initials: ES
authors.lastname: Akhramenko
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003911:Dextrans / Q000737:chemistry* / Q000494:pharmacology*; D008081:Liposomes / Q000737:chemistry* / Q000494:pharmacology*; D008297:Male; D049329:Nanostructures / Q000737:chemistry; D010084:Oxidation-Reduction; D010537:Peritoneum / Q000166:cytology* / Q000187:drug effects*; D010587:Phagocytosis / Q000187:drug effects; D011854:Radiochemistry; D051381:Rats
chemical_list: D003911:Dextrans; D008081:Liposomes