title: Reversible hepatic decerebration: a case report and review of the literature.
abstract: Hepatic encephalopathy is a syndrome of neuropsychiatric dysfunction caused by portosystemic venous shunting with or without the presence of intrinsic liver disease. Clinical presentations are variable ranging from an abnormal sleep pattern to somnolence and deep coma. Decerebrate and decorticate posturing, have been rarely reported with hepatic encephalopathy. We report a case of a 59-year-old-man with a history of Child-Pugh B liver disease secondary to chronic alcoholism who was admitted because of coma. He had a transjugular intrahepatic portosystemic shunt 3 months prior to his presentation. He was found to have decerebrating posture. He was treated for hepatic encephalopathy with complete recovery and resolution of the neurologic findings. The physician should be aware that decerebration and decortication posture can occur with hepatic encephalopathy and can be reversible.
authors.affiliation: Department of Medicine, The University of Kansas School of Medicine-Wichita, Wichita, Kansas 67214, USA. edgardwehbe@hotmail.com
authors.forename: Edgard
authors.initials: E
authors.lastname: Wehbe
authors.forename: Dany
authors.initials: D
authors.lastname: Saad
authors.forename: Fabian
authors.initials: F
authors.lastname: Delgado
authors.forename: Ha
authors.initials: H
authors.lastname: Ta
authors.forename: Smyrna Abou
authors.initials: SA
authors.lastname: Antoun
mesh_terms: D000437:Alcoholism / Q000150:complications; D003655:Decerebrate State / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D005442:Flumazenil / Q000627:therapeutic use; D006501:Hepatic Encephalopathy / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D005442:Flumazenil