title: 2,3-Functionalization of furans, benzofurans and thiophenes via magnesiation and sulfoxide-magnesium exchange.
abstract: The use of TMPMgCl.LiCl and iPrMgCl.LiCl allows a sequential 2,3-difunctionalization of various 2-arylsulfinyl furans, thiophenes and benzofurans. Subsequent use of the same reagents permits a selective full functionalization of all 4 positions of the furan and thiophene scaffolds.
authors.affiliation: Ludwig-Maximilians-Universität, Butenandtstr. 5-13, Munich, Germany.
authors.forename: Laurin
authors.initials: L
authors.lastname: Melzig
authors.forename: Christian B
authors.initials: CB
authors.lastname: Rauhut
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel
mesh_terms: D001554:Benzene / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry*; D015394:Molecular Structure; D012451:Safrole / Q000031:analogs & derivatives* / Q000737:chemistry; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005663:Furans; D013876:Thiophenes; D008274:Magnesium; D001554:Benzene; D012451:Safrole; C005746:sulfoxide