[Evaluation of phenomena detected on the surface of stirred coating liquid].
The main objective of this work was to study the effect of conditions of coating fluids through the properties of the coating fluid, film and coated product. With a more accurate understanding of the process the effects of the factors can be defined and by means of this the optimal composition can be determined and problem-free coating can be carried out. In this work the evaporation was studied. The effects of different operational factors on evaporation were studied through fluids of different compositions. In case of fluids containing ethanol a significant loss can be detected after a short period of time and this fact cannot be changed by the use of an antifoaming agent. The highest difference in effect of a given factor was detected for the stirring rate. The effect of the operational factors changed depending on the Composition. Stirring rate showed the highest sensitivity to the presence of the volatile component. These results can help to determine the critical control points and the optimal stirring circumstances.
Bölcskei
Eva
E
Szegedi Tudományegyetem, Gyógyszertechnológiai Intézet, Szeged, Eötvös u. 6.-6720.
Bajdik
János
J
Hódi
Klára
K
D002626:Chemistry, Pharmaceutical / Q000379:methods; D045424:Complex Mixtures; D004304:Dosage Forms; D010316:Particle Size; D012995:Solubility; D013499:Surface Properties; D013678:Technology, Pharmaceutical / Q000379:methods
D045424:Complex Mixtures; D004304:Dosage Forms