title: Early human studies of investigational agents: dose or microdose?
authors.forename: Lionel D
authors.initials: LD
authors.lastname: Lewis
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends; D015507:Drugs, Investigational / Q000008:administration & dosage*; D006801:Humans
chemical_list: D015507:Drugs, Investigational