title: Iridium-catalyzed asymmetric isomerization of primary allylic alcohols.
abstract: Nothing to sm(Ir)k at: Under appropriate reaction conditions, iridium hydride catalysts promote the isomerization of primary allylic alcohols. The best catalysts, like (R)-1 (P green, O red, N blue, Ir yellow), deliver the desired chiral aldehydes with excellent enantioselectivity and good yields. Mechanistic hypotheses have been developed on the basis of preliminary investigations.
authors.affiliation: Department of Organic Chemistry, University of Geneva, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland.
authors.forename: Luca
authors.initials: L
authors.lastname: Mantilli
authors.forename: David
authors.initials: D
authors.lastname: Gérard
authors.forename: Sonya
authors.initials: S
authors.lastname: Torche
authors.forename: Céline
authors.initials: C
authors.lastname: Besnard
authors.forename: Clément
authors.initials: C
authors.lastname: Mazet