[Takotsubo syndrome from original description up to now].
Stress-induced cardiomyopathy, also known as takotsubo syndrome, imitates an acute ST elevation myocardial infarction or an acute coronary syndrome, but without concomitant coronary artery disease. It mainly affects postmenopausal women, but no established epidemiologic data of this syndrome are available to date. Furthermore, the underlying etiologies are still largely unknown. The most frequently described trigger is strong emotional stress. Supportive therapy with aspirin, beta-blockers and angiotensin-converting enzyme inhibitors is recommended. The abnormal kinetics usually reverse or improve within 4-5 weeks. Compared with acute myocardial infarction, takotsubo cardiomyopathy carries a favorable prognosis. However, severe complications, including ventricular fibrillation and cardiogenic shock, may still occur.
Said
Samir M
SM
Innere Medizin-Kardiologie, Universitätsklinikum Magdeburg, Magdeburg, Germany. samir.said@med.ovgu.de
Albouaini
Khaled
K
Herold
Joerg
J
Hahn
Judit
J
Brucks
Steffen
S
Schmidt
Hendrik
H
Schmeisser
Alexander
A
Prondzinsky
Roland
R
Braun-Dullaeus
Ruediger C
RC
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000367:Age Factors; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage; D000818:Animals; D001241:Aspirin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D011379:Prognosis; D012307:Risk Factors; D012737:Sex Factors; D012770:Shock, Cardiogenic / Q000175:diagnosis; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000523:psychology
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin