title: [Present views of the etiology and pathogenesis of rapidly progressive periodontitis].
abstract: In modern dentistry, the problem of occurrence of atypical forms of periodontal inflammatory diseases, namely rapidly progressive periodontitis (RPP), has assumed a particular significance due the increasing incidence of this pathology. The paper considers the main lines of the etiology and pathogenesis of this disease. By taking into account the current data available in the literature, it may be assumed that the development ofa systemic inflammatory response, destabilization of cellular membranes, followed by the development of endothelial dysfunction and progressing microcirculatory disorders, are one of the mechanisms of the pathogenesis of RPP.
authors.forename: I N
authors.initials: IN
authors.lastname: Karpenko
authors.forename: N V
authors.initials: NV
authors.lastname: Bulkina
authors.forename: E V
authors.initials: EV
authors.lastname: Ponukalina
mesh_terms: D002462:Cell Membrane / Q000473:pathology; D004727:Endothelium / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D010518:Periodontitis / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology*; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000473:pathology / Q000503:physiopathology