[Effect of point injection of red-sage-root on the hip joint function in ischemic femoral head necrosis patients].
OBJECTIVE
To observe the therapeutic effect of point injection of Danshen (Red-sage-root) for treating ischemic necrosis of femoral head in patients.


METHODS
A total of 62 hips of ischemic femoral head necrosis were randomly divided into point-injection group (32 hips) and core decompression (CDC) group (30 hips) according to the random digits table method. Red-sage-root (freeze-dried) solved in 5 ml normal saline solution was injected into Huantiao (GB 30) and Juliao(GB 29) on the affected side, 2.5 ml for each point, 3 times a week, for 6 consecutive months. Patients of CDC group were treated by core decompression surgery. The therapeutic effect was evaluated by the "Evaluating Method for Adult Avascular Necrosis of Femoral Head" (issued in Dandong in 1995).


RESULTS
Compared with pre-treatment, scores of pain severity of two groups from the 1st month to the 6th month, joint-motion range, daily life activity and walking distance scores of point-injection group from the 1st month to the 6th month increased significantly (P<0.01, P<0.05); while those of joint-motion range, daily life activity and walking distance in CDC group had no apparent improvement (P>0.05). The difference values between post-and pre-treatment in the scores of pain severity, joint-motion range, daily life activity and walking distance in point-injection group were all significantly higher than those in CDC group (P<0.01).


CONCLUSIONS
Point-injection of red-sage-root can effectively relieve the pain severity, improve the hip joint-motion function and daily life activity in ischemic femoral head necrosis patients.
Zhang
Hai-feng
HF
Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou 310006, China. 7112zhf@sohu.com
Zhang
Shu-yan
SY
Liu
Jin-min
JM
D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005271:Femur Head Necrosis / Q000188:drug therapy* / Q000503:physiopathology; D006621:Hip Joint / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D007267:Injections; D007511:Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010618:Phenanthrolines / Q000008:administration & dosage*; D027561:Salvia miltiorrhiza; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; C028972:dan-shen root extract