title: Merkel cell polyomavirus strains in patients with merkel cell carcinoma.
abstract: We investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens, but none of the non-MCC neuroendocrine carcinomas specimens, had MCPyV. Strains from France and the United States were similar.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, Unit 618, Tours, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Touzé
authors.forename: Julien
authors.initials: J
authors.lastname: Gaitan
authors.forename: Annabel
authors.initials: A
authors.lastname: Maruani
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Le Bidre
authors.forename: Angélique
authors.initials: A
authors.lastname: Doussinaud
authors.forename: Christine
authors.initials: C
authors.lastname: Clavel
authors.forename: Anne
authors.initials: A
authors.lastname: Durlach
authors.forename: François
authors.initials: F
authors.lastname: Aubin
authors.forename: Serge
authors.initials: S
authors.lastname: Guyétant
authors.forename: Gérard
authors.initials: G
authors.lastname: Lorette
authors.forename: Pierre
authors.initials: P
authors.lastname: Coursaget
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D036022:Capsid Proteins / Q000235:genetics; D015266:Carcinoma, Merkel Cell / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D018862:Merkel Cells / Q000821:virology*; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D011120:Polyomavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D027601:Polyomavirus Infections / Q000821:virology*; D017422:Sequence Analysis, DNA; D012878:Skin Neoplasms / Q000821:virology*; D014412:Tumor Virus Infections / Q000821:virology*
chemical_list: D036022:Capsid Proteins; D004279:DNA, Viral; C062481:VP1 protein, polyomavirus