title: Early laparoendoscopic rendezvous for acute biliary pancreatitis: preliminary results.
abstract: BACKGROUND
  Early restored patency of the papilla has been hypothesized to reduce complications and mortality of acute biliary pancreatitis. The aim of this study was to evaluate the role of urgent laparoscopic cholecystectomy with intraoperative cholangiography and rendezvous when necessary in acute biliary pancreatitis natural history.
  
  
  METHODS
  Patients observed in the early stage of an acute biliary pancreatitis were included in the study. Operative risk assessment based on American Society of Anesthesiologists (ASA) score allowed the performance of urgent laparoscopic cholecystectomy within 72 h from onset of symptoms in 55 patients and a delayed intervention during the same admission in 21 patients. Intraoperative cholangiography was performed in all cases, and clearance of common bile duct was performed by flushing when possible, or rendezvous when necessary. Evolution of pancreatitis was evaluated with clinical and radiological monitoring.
  
  
  RESULTS
  Urgent laparoscopic cholecystectomy was performed in all cases without conversion. At intraoperative cholangiography common bile duct was free in 25 patients, a papillary spasm was observed in 9, and common bile duct stones in 21 patients. Patency of the papilla was restored by flushing in 13 patients, while a rendezvous was necessary in 17 patients. The rate of organ failure and pancreatic necrosis was 1.8%, overall mortality was 1.8%, and overall morbidity 21.8%. No infectious complications of peripancreatic collections were observed.
  
  
  CONCLUSIONS
  Urgent laparoscopic cholecystectomy with selective intraoperative rendezvous may be considered as a treatment option in the early stage of acute biliary pancreatitis.
authors.affiliation: Department of Surgery, University Hospital of Verona, Verona, Italy. gborz@libero.it
authors.forename: G
authors.initials: G
authors.lastname: Borzellino
authors.forename: F
authors.initials: F
authors.lastname: Lombardo
authors.forename: A M
authors.initials: AM
authors.lastname: Minicozzi
authors.forename: M
authors.initials: M
authors.lastname: Donataccio
authors.forename: C
authors.initials: C
authors.lastname: Cordiano
mesh_terms: D000328:Adult; D000368:Aged; D014670:Ampulla of Vater; D002404:Catheterization / Q000379:methods*; D002758:Cholangiography; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D042883:Choledocholithiasis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery* / Q000628:therapy; D002769:Cholelithiasis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D042241:Early Diagnosis; D004630:Emergencies; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D011446:Prospective Studies; D015641:Radiography, Interventional; D007507:Therapeutic Irrigation