Furans versus 4H-pyrans: catalyst-controlled regiodivergent tandem Michael addition-cyclization reaction of 2-(1-alkynyl)-2-alken-1-ones with 1,3-dicarbonyl compounds.
The DBU-catalyzed reaction of 1-(1-alkynyl)-2-alken-1-ones with 1,3-dicarbonyl compounds produces 4H-pyrans in moderate to excellent yield, whereas the cationic Pd(ii)-catalyzed reaction affords furans regioselectively.
Xiao
Yuanjing
Y
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N, Zhongshan Road, Shanghai 200062, PR China.
Zhang
Junliang
J