title: Nasal osteoma in a dairy cow: a combined clinical, imaging and histopathological approach to diagnosis.
abstract: An 8-year-old Brown Swiss dairy cow was presented with unilateral epistaxis and mild inspiratory stridor. At that time endoscopic examination revealed a smooth-surfaced mass within the left nasal cavity. Biopsy samples were collected and a diagnosis of fibrosarcoma was made. Eighteen months later the animal developed severe respiratory distress that led to difficulties in feeding and consequently to emaciation and a dramatic drop in milk production. The cow was humanely destroyed and submitted for post-mortem examination. The head was subject to further investigation by radiography, computed tomography and magnetic resonance imaging. These techniques revealed a non-infiltrative, well-circumscribed mass of both radiodense and heterogeneously intense structures. Histopathological examination revealed a mass consisting of well-differentiated and interlacing bone trabeculae lined by osteoblasts and multinucleated osteoclasts. In contrast to the initial diagnosis, the later diagnostic approaches supported the diagnosis of osteoma.
authors.affiliation: General Practice for Small and Large Animals, Schigliana 182, 7554 Sent, Switzerland. kunowuersch@mac.com
authors.forename: K
authors.initials: K
authors.lastname: Wuersch
authors.forename: M
authors.initials: M
authors.lastname: Bischoff
authors.forename: R
authors.initials: R
authors.lastname: Thoma
authors.forename: M S
authors.initials: MS
authors.lastname: Matter
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D037901:Euthanasia, Animal; D017809:Fatal Outcome; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000662:veterinary; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D009296:Nasal Cavity / Q000473:pathology*; D010016:Osteoma / Q000473:pathology / Q000662:veterinary*; D012888:Skull Neoplasms / Q000473:pathology / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary