The fate of human Treg cells.
In this issue of Immunity, Miyara et al. (2009) demonstrate that FoxP3(+) cells in human peripheral blood are heterogeneous in function, and CD45RA expression defines their different stages of differentiation.
Battaglia
Manuela
M
San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET) Milano, Italy.
Roncarolo
Maria Grazia
MG
D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology / Q000378:metabolism*; D002454:Cell Differentiation / Q000276:immunology; D051858:Forkhead Transcription Factors / Q000276:immunology / Q000378:metabolism*; D006684:HLA-DR Antigens / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D060889:Inducible T-Cell Co-Stimulator Protein; D017493:Leukocyte Common Antigens / Q000276:immunology / Q000378:metabolism*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism; D013950:Thymus Gland / Q000276:immunology* / Q000378:metabolism
D000945:Antigens, Differentiation, T-Lymphocyte; C418974:FOXP3 protein, human; D051858:Forkhead Transcription Factors; D006684:HLA-DR Antigens; C556692:ICOS protein, human; D060889:Inducible T-Cell Co-Stimulator Protein; D017493:Leukocyte Common Antigens