A new dihydrodibenzodioxinone from Hypericum x 'Hidcote'.
One new compound, 4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one (1), was isolated from the aerial parts of the hybrid Hypericum x 'Hidcote', together with 8 known compounds: caryophyllene-4,5-epoxide, quercetin, quercitrin, quercetin-3-O-beta-D-galactopyranoside, epicatechin, betulinic acid methyl ester, beta-sitosterol and beta-sitosterol glucoside. The structure of the new compound, as well as its absolute configuration, was established by means of spectroscopic data analyses, including 2D NMR spectroscopy and X-ray structural analysis.
Sun
Longru
L
Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Rahman
M Mukhlesur
MM
Skelton
Brian W
BW
Gibbons
Simon
S
D004147:Dioxins / Q000737:chemistry / Q000302:isolation & purification*; D020902:Hypericum / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D018547:Plant Stems
C553852:4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one; D004147:Dioxins; D010936:Plant Extracts