title: A clinicopathologic correlation in the diagnosis of periradicular lesions of extracted teeth.
abstract: OBJECTIVE
  We aimed to determine the contributory percentage of histopathologic diagnoses of routine biopsies and to ascertain the possible indicators for histopathologic examination to confirm the clinical diagnosis of periradicular lesions of extracted teeth.
  
  
  METHODS
  This was a prospective study carried out over a period of 8 months on patients who had single tooth extraction and routine histopathologic examination of recoverable periradicular tissues from extracted teeth.
  
  
  RESULTS
  A total of 136 patients participated in this study. There was a male/female incidence ratio of 3:2 and most of the patients with histopathologically diagnosed lesions were within the first, second, and third decades of life (n = 49, 36.0%). Seventy-five (55.2%) cases had histopathologically diagnosed periradicular lesions, which were mostly periapical abscess (n = 30, 22.8%) and inflammatory (periapical) granuloma (n = 23, 16.9%). Some clinical and radiologic features were associated significantly with histopathologic diagnosis of some periradicular lesions (P < .05). There also was a significant correlation of clinical diagnosis with histopathologic diagnosis of inflammatory (periapical) granuloma, periapical abscess, chronic osteomyelitis, and Burkitt's lymphoma (P < .05).
  
  
  CONCLUSIONS
  This study shows a higher contributory percentage of histopathologic diagnoses after routine biopsies, compared to previous reports from selected biopsies of periradicular lesions. We identified clinical indicators for predicting possible histopathologic diagnosis of some periradicular lesions, in particular, those that predict possible histologic diagnosis of neoplastic periradicular lesions.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Pathology, College of Medical Sciences, University of Benin, Benin City, Edo State, Nigeria. omoregiefo@yahoo.com
authors.forename: Osawe Felix
authors.initials: OF
authors.lastname: Omoregie
authors.forename: Birch Dauda O
authors.initials: BD
authors.lastname: Saheeb
authors.forename: Onatolu
authors.initials: O
authors.lastname: Odukoya
authors.forename: Michael Akin
authors.initials: MA
authors.lastname: Ojo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003751:Dental Fistula / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000473:pathology; D007573:Jaw Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010483:Periapical Diseases / Q000473:pathology*; D010485:Periapical Periodontitis / Q000473:pathology; D011446:Prospective Studies; D014081:Tooth Extraction; D019553:Tooth, Nonvital / Q000473:pathology / Q000601:surgery; D055815:Young Adult