Synthesis and self-assembly of amphiphilic hyperbranched polyglycerols modified with palmitoyl chloride.
A series of palmitoyl chloride-grafted hyperbranched polyglycerols were synthesized through cationic ring-opening polymerization and end-group modification. The obtained grafted copolymer of HPG-C16 possesses a hydrophilic hyperbranched polyether core and many hydrophobic alkyl arms, which shows interesting self-assembly behavior in THF and water. The results indicate that the copolymers with a relatively high alkyl grafting ratio can form unimolecular micelles in THF and will further assemble into giant vesicles around 1-10 microm in THF/water mixed solvents. However, the HPG-C16 with a low alkyl grafting ratio of 15.6% can directly assemble into vesicles in THF and form micelles in water.
Cheng
Haixing
H
College of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, People's Republic of China.
Wang
Siguang
S
Yang
Jintian
J
Zhou
Yongfeng
Y
Yan
Deyue
D
D005990:Glycerol / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D046529:Microscopy, Electron, Transmission; D010168:Palmitates / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
D010168:Palmitates; D011108:Polymers; C043941:polyglycerol; C032023:palmitoyl chloride; D005990:Glycerol