Cation-complexation behavior of template-assembled synthetic G-quartets.
We report the preparation and solution study of a set of template-assembled synthetic G-quartets (TASQs) bound to different cations. These G-quartet baskets effectively extract cations of different sizes and valencies. They form isolated G-quartets with small cations such as Na+ and Sr(2+), and dimeric assemblies with larger cations such as Cs+. Their structures were determined by using (1)H NMR spectroscopy, and their sizes were evaluated by using a series of pulsed-field gradient NMR experiments. The effect of anion has been studied, and the cation selectivities have been investigated by a series of competition experiments.
Nikan
Mehran
M
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver V6T 1Z1, Canada.
Sherman
John C
JC
D002412:Cations / Q000737:chemistry; D002586:Cesium / Q000737:chemistry*; D054856:G-Quadruplexes; D009682:Magnetic Resonance Spectroscopy; D010316:Particle Size; D012964:Sodium / Q000737:chemistry*; D013324:Strontium / Q000737:chemistry*
D002412:Cations; D002586:Cesium; D012964:Sodium; D013324:Strontium