title: Persistent subcutaneous nodules after immunotherapy injections for allergic asthma.
abstract: Adverse effects of desensitization injections mostly consist of local transient reactions. Rarely, persistent subcutaneous nodular lesions may also develop at the site of injection. These reactions have been attributed to the vaccines containing aluminium hydroxide. Aluminium hydroxide is used as an adjuvant in vaccines and hyposensitization solutions. We describe a patient who presented persistent, itchy subcutaneous nodules as a local reaction to allergen immunotherapy for the treatment of allergic asthma.
authors.affiliation: Department of Dermatology, Medical Faculty, Ondokuz Mayis University, Kurupelit, Samsun, Turkey. mozden@omu.edu.tr
authors.forename: Müge G
authors.initials: MG
authors.lastname: Ozden
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kefeli
authors.forename: Fatma
authors.initials: F
authors.lastname: Aydin
authors.forename: Nilgün
authors.initials: N
authors.lastname: Senturk
authors.forename: Tayyar
authors.initials: T
authors.lastname: Canturk
authors.forename: Ahmet Y
authors.initials: AY
authors.lastname: Turanli
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D000536:Aluminum Hydroxide / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000628:therapy*; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000009:adverse effects*; D007271:Injections, Intradermal; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology*
chemical_list: D000276:Adjuvants, Immunologic; D000536:Aluminum Hydroxide