Thoracic paravertebral ganglioneuroma with high immunohistochemical expression of TrkA.
A 21-year-old man, who had previously undergone a total resection for a retroperitoneal ganglioneuroblastoma at 7 months of age, was revealed to have a thoracic paravertebral ganglioneuroma, in which immunohistochemical expression of neuron-specific enolase and neurofilament was noted. Furthermore, immunohistochemical expression of TrkA, which is a high-affinity receptor for nerve growth factor, was evident. Although the exact histogenesis remains uncertain, TrkA was considered to be involved in the development of this thoracic paravertebral tumor.
Nishio
S
S
Department of Neurosurgery, Neurological Institute, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. shunji@ns.med.kyushu-u.ac.jp
Hamada
Y
Y
Nakagawara
A
A
Haga
S
S
Suzuki
S
S
Fukui
M
M