title: Significance of heart rate in the prevalence of metabolic syndrome and its related risk factors in Japanese.
abstract: BACKGROUND
  Autonomic dysfunction is thought to be an important mechanism of metabolic syndrome (MetS), but there has not been a study on the direct association between MetS and heart rate (HR) in Japanese.
  
  
  RESULTS
  The association between MetS and HR was examined using medical check-up data from 1,880 men and 1,079 women. HR was significantly higher in MetS subjects than in non-MetS subjects in both men and women (P<0.0001 in men, P<0.001 in women). The prevalence of MetS increased linearly through the quartiles of HR in both men and women. HR was significantly correlated with MetS-related risk factors other than uric acid in men and other than uric acid, body mass index, waist circumference, and high-density lipoprotein cholesterol in women.
  
  
  CONCLUSIONS
  The prevalence of MetS increased linearly with the increase in HR among Japanese men and women, and HR was significantly correlated with MetS-related risk factors.
authors.affiliation: Medical Check-up Center, Tachikawa Medical Center, Nagaoka, Japan. ijie@venus.sannet.ne.jp
authors.forename: Eiji
authors.initials: E
authors.lastname: Oda
authors.forename: Ryu
authors.initials: R
authors.lastname: Kawai
mesh_terms: D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000503:physiopathology*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D014527:Uric Acid / Q000097:blood; D055105:Waist Circumference
chemical_list: D008076:Cholesterol, HDL; D014527:Uric Acid