title: [Central nervous system dysgerminoma: a clinicopathological study of 3 cases].
abstract: BACKGROUND
  Intracranial germ cell tumors are rarely seen and typically localize in the pineal or suprasellar region. The largest category of germ cell tumors is dysgerminoma.
  
  
  OBJECTIVE
  to describe clinicopathological features and immunohistochemical profile of dysgerminomas.
  
  
  METHODS
  We report three cases of central nervous system dysgerminomas. There were two young women and a man who were 6, 11 and 23-year-old. They presented with symptoms of insipidus diabetes (n=3) with association to visual field defects in the third case. Radiological findings showed a supra seller lesion in two cases. Double localization in the pineal and suprasellar regions was seen in the third case. Histologic examination and immunohistochemical study of surgical specimen were consistent with primary central nervous system dysgerminoma.
authors.affiliation: Service d'Anatomie et de Cytologie Pathologiques, Hôpital la Rabta.
authors.forename: Selma
authors.initials: S
authors.lastname: Bellil
authors.forename: Emna
authors.initials: E
authors.lastname: Braham
authors.forename: Faten
authors.initials: F
authors.lastname: Limaiem
authors.forename: Khadija
authors.initials: K
authors.lastname: Bellil
authors.forename: Ines
authors.initials: I
authors.lastname: Chelly
authors.forename: Amina
authors.initials: A
authors.lastname: Mekni
authors.forename: Slim
authors.initials: S
authors.lastname: Haouet
authors.forename: Moncef
authors.initials: M
authors.lastname: Zitouna
authors.forename: Hafedh
authors.initials: H
authors.lastname: Jemel
authors.forename: Moncef
authors.initials: M
authors.lastname: Khaldi
authors.forename: Nidhameddine
authors.initials: N
authors.lastname: Kchir
mesh_terms: D016543:Central Nervous System Neoplasms / Q000473:pathology* / Q000628:therapy; D002648:Child; D004407:Dysgerminoma / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D055815:Young Adult