[Hypertension and the brain].
Hypertension is a major and modifiable risk factor of stroke and dementia. Hypertension causes remodelling of the cerebral resistance vessels, impairing their tolerance to very low blood pressure. In primary prevention of stroke, the effect of beta-blockers is inferior to other classes of antihypertensives. In secondary prevention of stroke, ACE-inhibitors and angiotensin blockers may be recommended as first choice drugs. Lowering of the blood pressure is, however, more important than the choice of drug.
Christensen
Hanne
H
Neurologisk Afdeling N, Bispebjerg Hospital, DK-2400 København NV. hc04@bbh.regionh.dk
Strandgaard
Svend
S
D000959:Antihypertensive Agents / Q000627:therapeutic use; D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D003704:Dementia / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D012307:Risk Factors; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control; D014655:Vascular Resistance / Q000502:physiology
D000959:Antihypertensive Agents