title: Anthropometric indices of obesity and the prediction of cardiovascular risk factors in an Iranian population.
abstract: The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome are increasing globally. The present study was conducted in an attempt to define optimal cutoff values for several anthropometric variables in an Iranian population, as these may vary with ethnicity. Iranian subjects (2483 men and 2445 women), aged 15-65 years, were recruited using a cluster-stratified sampling method from rural and urban areas within the Khorasan province. Receiver operating characteristics (ROC) analysis was used to define optimal anthropometric cutoff values. The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome were 28, 5.5, 67, and 39.9%, respectively. The gender-specific cutoff values for waist:height ratio to predict hypertension, diabetes, dyslipidemia, and metabolic syndrome among men were 0.52 (sensitivity = 66%; specificity = 66%), 0.54 (sensitivity = 65%; specificity = 65%), 0.50 (sensitivity = 58%; specificity = 57%), and 0.53 (sensitivity = 73%; specificity = 70%), and for women were 0.59 (sensitivity = 61%; specificity = 61%), 0.61 (sensitivity = 64%; specificity = 64%), 0.57 (sensitivity = 61%; specificity = 61%), and 0.59 (sensitivity = 77%; specificity = 77%) (p < 0.05). Significant correlations were found between waist:height ratio and hypertension, diabetes mellitus, dyslipidemia, and metabolic syndrome, particularly in women. Waist circumference cutoffs were higher for women than men for hypertension, diabetes mellitus, and dyslipidemia.
authors.affiliation: Department of Biochemistry and Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran. aziminm@mums.ac.ir
authors.forename: Mohsen
authors.initials: M
authors.lastname: Azimi-Nezhad
authors.forename: Majid
authors.initials: M
authors.lastname: Ghayour-Mobarhan
authors.forename: Mohammad
authors.initials: M
authors.lastname: Safarian
authors.forename: Habibollah
authors.initials: H
authors.lastname: Esmailee
authors.forename: Seyed Mohammad Reza
authors.initials: SM
authors.lastname: Parizadeh
authors.forename: Maryam
authors.initials: M
authors.lastname: Rajabi-Moghadam
authors.forename: Arezoo
authors.initials: A
authors.lastname: Gholami
authors.forename: Mohammad
authors.initials: M
authors.lastname: Reza Oladi
authors.forename: Gordon A
authors.initials: GA
authors.lastname: Ferns
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D011237:Predictive Value of Tests; D012307:Risk Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose