Health risk assessment of inorganic arsenic intake of Ronphibun residents via duplicate diet study.
OBJECTIVE
To assess health risk from exposure to inorganic arsenic via duplicate portion sampling method in Ronphibun residents.


METHODS
A hundred and forty samples (140 subject-days) were collected from participants in Ronphibun sub-district. Inorganic arsenic in duplicate diet sample was determined by acid digestion and hydride generation-atomic absorption spectrometry. Deterministic risk assessment is referenced throughout the present paper using United States Environmental Protection Agency (U.S. EPA) guidelines.


RESULTS
The average daily dose and lifetime average daily dose of inorganic arsenic via duplicate diet were 0.0021 mg/kg/d and 0.00084 mg/kg/d, respectively. The risk estimates in terms of hazard quotient was 6.98 and cancer risk was 1.26 x 10(-3).


CONCLUSIONS
The results of deterministic risk characterization both hazard quotient and cancer risk from exposure inorganic arsenic in duplicate diets were greater than safety risk levels of hazard quotient (1) and cancer risk (1 x 10(-4)).
Saipan
Piyawat
P
Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. psaipan@yahoo.com
Ruangwises
Suthep
S
D000328:Adult; D000368:Aged; D020261:Arsenic Poisoning / Q000453:epidemiology* / Q000209:etiology; D001152:Arsenicals; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D009749:Nutrition Surveys; D012016:Reference Values; D018570:Risk Assessment; D012307:Risk Factors; D012989:Soil Pollutants; D013054:Spectrophotometry, Atomic; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology
D001152:Arsenicals; D012989:Soil Pollutants