title: Neurons that fire together also conspire together: is normal sleep circuitry hijacked to generate epilepsy?
abstract: Brain circuits oscillate during sleep. The same circuits appear to generate pathological oscillations. In this review, we discuss recent advances in our understanding of how epilepsy co-opts normal, sleep-related circuits to generate seizures.
authors.affiliation: Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Beenhakker
authors.forename: John R
authors.initials: JR
authors.lastname: Huguenard
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D004827:Epilepsy / Q000473:pathology*; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000503:physiopathology; D009434:Neural Pathways / Q000503:physiopathology; D009474:Neurons / Q000502:physiology*; D010507:Periodicity; D012890:Sleep / Q000502:physiology*