title: Evaluation of adherence and factors affecting adherence to combination antiretroviral therapy among White, Hispanic, and Black men in the MACS Cohort.
abstract: OBJECTIVE
  This study investigated levels of adherence to antiretroviral therapy in white, Hispanic, and black men and isolated factors associated with adherence among each racial group.
  
  
  METHODS
  Data were collected from 1102 men enrolled in the Multicenter AIDS Cohort Study followed between April 2002 and October 2006. Self-reported 100% adherence was defined as taking all doses and pills over the previous 4-day period, reporting not typically skipping any medications, and reporting always following the medication schedule. Variables associated with adherence were determined by multilevel logistic regression for each racial group. Adherence was also analyzed by ethnicity within racial groups.
  
  
  RESULTS
  After controlling for confounders, we found that Hispanics were 2.16 times and blacks were 1.37 times more likely than whites to not report 100% adherence (95% confidence interval 1.47 to 3.18 and 1.05 to 1.79, respectively). Hispanics with ethnic backgrounds from Central and South America and the Caribbean had lower rates of adherence. Blacks with ethnic backgrounds from the Caribbean had lower rates of adherence than those from other regions.
authors.affiliation: Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095-1772, USA.
authors.forename: Debora Lee
authors.initials: DL
authors.lastname: Oh
authors.forename: Farjad
authors.initials: F
authors.lastname: Sarafian
authors.forename: Anthony
authors.initials: A
authors.lastname: Silvestre
authors.forename: Todd
authors.initials: T
authors.lastname: Brown
authors.forename: Lisa
authors.initials: L
authors.lastname: Jacobson
authors.forename: Sheila
authors.initials: S
authors.lastname: Badri
authors.forename: Roger
authors.initials: R
authors.lastname: Detels
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D044383:Black People; D015331:Cohort Studies; D015658:HIV Infections / Q000188:drug therapy*; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D012307:Risk Factors; D014481:United States; D044465:White People; D001741:Black or African American; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents