Clinical characteristics and endoscopic treatment with cyanoacrylate injection in patients with duodenal varices.
OBJECTIVE
To summarize the clinical characteristics and evaluate the effectiveness of cyanoacrylate injection in patients with duodenal varices (DV).


METHODS
Between June 2003 and June 2008 all patients with DV (n=14) were analyzed retrospectively. Their clinical characteristics, endoscopic diagnoses and values of endoscopic cyanoacrylate injection were summarized.


RESULTS
Fourteen of 396 patients receiving endoscopic treatment for upper gastroesophageal varices were diagnosed with DV. Four of these patients underwent endoscopic cyanoacrylate injection, with satisfactory results. No episodes of rebleeding occurred after 7-30 months' follow-up. Viral hepatitis-associated cirrhosis is the most common cause of DV (8/14), and the second section of the duodenum is the most common location of DV (14/14).


CONCLUSIONS
The second section of the duodenum should be routinely endoscopically examined to identify and evaluate DV in all patients with gastroesophageal varices, and endoscopic cyanoacrylate injection appears to be a simple and effective hemostatic measure for DV bleeding.
Liu
Yingdi
Y
Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China.
Yang
Jing
J
Wang
Jianhua
J
Chai
Guojun
G
Sun
Guohui
G
Wang
Zhiqiang
Z
Yang
Yunsheng
Y
D000328:Adult; D000368:Aged; D003487:Cyanoacrylates / Q000008:administration & dosage*; D004386:Duodenum / Q000098:blood supply*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014648:Varicose Veins / Q000628:therapy*
D003487:Cyanoacrylates