[Renal amyloidosis during Behçet's disease. Study of one case].
BACKGROUND
Amyloidosis in Behçet's disease is rare and has a poor outcome.


OBJECTIVE
Report a new case.


METHODS
We report a case of a 38-year-old Tunisian woman who presented with Behçet's disease and nephrotic syndrome. Renal biopsy showed amyloid deposition consistent with AA type. She had not any associated disease that might be an additional cause of secondary amyloidosis. She was treated by colchicine. After 3 years, proteinuria had disappeared and persisted negative 11 years after the diagnosis. A second renal biopsy showed the persistence of amyloidosis.


CONCLUSIONS
As amyloidosis is one of the prognostic factors affecting survival in Behçet's disease, patients with this disease should be screened for amyloidosis. Administration of colchicine to these patients may be beneficial.
Azzabi
Samira
S
Service de Médecine Interne B, Hôpital Charles Nicolle, Tunis, Tunisie.
Ben Hassine
Lamia
L
Cherif
Eya
E
Kooli
Chekib
C
Kaouache
Zouleikha
Z
Goucha
Rim
R
Khedher
Adel
A
Ben Moussa
Fatma
F
Khalfallah
Narjes
N
D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000188:drug therapy; D001528:Behcet Syndrome / Q000150:complications*; D003078:Colchicine / Q000627:therapeutic use; D005260:Female; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000188:drug therapy
D006074:Gout Suppressants; D003078:Colchicine