Tissue factor in brain is not saturated with factor VIIa: implications for factor VIIa dosing in intracerebral hemorrhage.
Hoffman
Maureane
M
Pathology & Laboratory Medicine Service (113), Durham VA Medical Center, 508 Fulton St, Durham, NC 27705, USA. maureane.hoffman@med.va.gov
Monroe
Dougald M
DM
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002543:Cerebral Hemorrhage / Q000188:drug therapy / Q000378:metabolism*; D015942:Factor VIIa / Q000008:administration & dosage* / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D009928:Organ Specificity / Q000187:drug effects / Q000502:physiology; D013925:Thromboplastin / Q000378:metabolism*
D013925:Thromboplastin; D015942:Factor VIIa