Neurotoxic syndrome developed after taking sertraline and risperidone.
Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here we present a case of 19-year-old man who experienced serotonin syndrome caused by sertraline intake, and consecutive neuroleptic malignant syndrome by risperidone. This case suggests that these two syndromes can be concomitantly induced in some patients who are susceptible to these drugs. Clinicians may have to pay close attention to this problem when prescribing drugs to patients who previously showed sensitivity to CNS-acting drugs.
Kim
Jeong-Min
JM
Department of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Lee
Soon-Tae
ST
Song
Eun-Cheol
EC
Jung
Keun-Hwa
KH
Sinn
Dong-In
DI
Chung
Hakjae
H
Chu
Kon
K
Kim
Manho
M