Severe episodic memory impairment in a patient with clinical features compatible with corticobasal degeneration.
Corticobasal degeneration (CBD) is a progressive neurodegenerative disorder characterized by asymmetric parkinsonism associated with apraxia, cortical sensory loss, and alien-limb phenomenon. Neuropsychological testing in patients with CBD typically shows deficits in executive functions, praxis, language, and visuospatial functioning, but not in memory. We report a CBD patient with severely impaired memory function but relatively mild motor symptoms. Detailed neuropsychological assessment showed significant verbal and visual memory deficits accompanied by frontal executive dysfunctions. Our observations indicate that CBD can in rare cases present with severe episodic memory impairment associated with frontal executive dysfunctions in the early stage of illness.
Kim
Sung Kwan
SK
Department of Neurology, Dong-A University College of Medicine, Busan, Korea.
Park
Kyung Won
KW
Kang
Do-Young
DY
Cha
Jae Kwan
JK
Kim
Sang-Ho
SH
Kim
Jae Woo
JW