title: Structural features of the Zn(2+) complex with the single repeat region of "prion related protein" (PrP-rel-2) of zebrafish zPrP63-70 fragment.
abstract: The interaction between Zn(2+) and the single repeat of PrP-rel-2 of zebrafish at physiological pH was investigated by NMR spectroscopy; the chemical shift mapping and the proton-proton distances were used to obtain the structural model of the Zn(2+) complex.
authors.affiliation: Department of Chemistry, University of Siena, via Aldo Moro, 53100, Siena, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Camponeschi
authors.forename: Elena
authors.initials: E
authors.lastname: Gaggelli
authors.forename: Henryk
authors.initials: H
authors.lastname: Kozłowski
authors.forename: Daniela
authors.initials: D
authors.lastname: Valensin
authors.forename: Gianni
authors.initials: G
authors.lastname: Valensin
mesh_terms: D000818:Animals; D001665:Binding Sites; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism; D018621:PrPC Proteins / Q000737:chemistry* / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation; D015027:Zebrafish; D029961:Zebrafish Proteins / Q000737:chemistry* / Q000378:metabolism; D015032:Zinc / Q000737:chemistry* / Q000378:metabolism
chemical_list: D010446:Peptide Fragments; D018621:PrPC Proteins; D029961:Zebrafish Proteins; C543435:prnpa protein, zebrafish; D015032:Zinc