title: Small large-cell neuroendocrine carcinoma in a patient with pulmonary emphysema.
abstract: Large-cell neuroendocrine carcinomas (LCNECs) are relatively rare, and most reported occurrences tend to involve relatively large tumors. We report a small LCNEC in a 63-year-old male patient with pulmonary emphysema. The peripheral pulmonary nodule did not have lobulation and spiculation, and it was difficult to establish correct diagnosis before surgery because of its small size and effect of surrounding emphysematous change.
authors.affiliation: Divisions of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-city, Ibaraki, Japan.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Kagohashi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Satoh
authors.forename: Koichi
authors.initials: K
authors.lastname: Kurishima
authors.forename: Norihiro
authors.initials: N
authors.lastname: Kikuchi
authors.forename: Hiroichi
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Kiyohisa
authors.initials: K
authors.lastname: Sekizawa
mesh_terms: D018287:Carcinoma, Large Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012907:Smoking / Q000009:adverse effects; D014057:Tomography, X-Ray Computed