title: Palliative radiotherapy for the skin metastasis of ovarian cancer: a case report and review of the literature.
abstract: Ovarian cancer which is the most common cause of death among all gynecological malignancies tends to metastasize through peritoneal cavity. Skin metastasis, however, is a very rare clinical entity and related with poor prognosis. We report a 43-year-old patient with recurrent ovarian cancer presented with extensive abdominal skin metastasis approximately 6 years after the initial diagnosis. Patient was treated with radiotherapy with electrons to a total dose of 37.5 Gy given in 2.5 Gy per fraction per day. Skin metastasis showed good response to radiotherapy, and the patient has been alive for 7 months after radiotherapy with no recurrences on abdominal skin. Radiotherapy might be considered as an efficient palliative treatment option for the skin metastasis of ovarian cancer.
authors.affiliation: Department of Radiation Oncology, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Turkey. senem.demirci@ege.edu.tr
authors.forename: Senem
authors.initials: S
authors.lastname: Demirci
authors.forename: Fatma
authors.initials: F
authors.lastname: Yavas
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Ozsaran
authors.forename: Aydin
authors.initials: A
authors.lastname: Ozsaran
authors.forename: Yilmaz
authors.initials: Y
authors.lastname: Dikmen
authors.forename: Osman
authors.initials: O
authors.lastname: Zekioglu
authors.forename: Bulent
authors.initials: B
authors.lastname: Karabulut
authors.forename: Arif B
authors.initials: AB
authors.lastname: Aras
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D018283:Cystadenocarcinoma, Papillary / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000209:etiology; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010166:Palliative Care; D011855:Radiodermatitis / Q000209:etiology; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D012878:Skin Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D013684:Telangiectasis / Q000209:etiology