Remission of proteinuria with treatment of Actinomyces infection: eradicating a cause of secondary membranous glomerulopathy suppresses nephrotic syndrome.
Eradication of a cause of secondary membranous glomerulopathy might suppress nephrotic syndrome. Here we report a patient with membranous nephropathy (MN), whose proteinuria entered complete remission after treating actinomycosis. A 45-year-old woman presented with nephrotic syndrome and was diagnosed as having MN. Her urine protein excretion was 5.3 g/day and the serum creatinine level was 70.7 micromol/L. When we searched for causes of secondary MN, pelvic actinomycosis was detected. After removing the pelvic abscess surgically, we administered amoxicillin for 6 months. Then, her proteinuria had decreased to <0.1 g/day, and since it entered remission, she has not relapsed.
Yoon
Soo Young
SY
Department of Nephrology, Kwandong University College of Medicine, Goyang, Korea. diva502@kd.ac.kr
Lee
Sang Choel
SC
Park
Young Jun
YJ
Rha
Seo-Hee
SH
D039903:Actinobacteria; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000150:complications / Q000209:etiology / Q000628:therapy*; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology / Q000628:therapy*; D011507:Proteinuria / Q000209:etiology / Q000628:therapy*; D012074:Remission Induction