title: [Are patients in randomised controlled trials of psychotherapy representative for clinical practice?].
abstract: BACKGROUND
  In the debate about evidence-based psychotherapy it is often assumed that randomised controlled trials (RCT's) have a limited generalizable. Among the reasons for this assumption are the strict exclusion criteria which rule out patients with comorbidity or multiple diagnoses.
  
  
  OBJECTIVE
  To investigate whether these strict exclusion criteria do effect the generalizable of RCT's.
  
  
  METHODS
  Narrative overview of the research literature on psychotherapy.
  
  
  RESULTS
  We found that the exclusion criteria infact have less effect than expected on the generalizable.
  
  
  CONCLUSIONS
  Most patients from clinical practice can indeed be included in a RCT. Recent RCT's also include many patients with comorbidity.
authors.affiliation: Universitair Psychiatrisch Centrum (UPC) van de Katholieke Universiteit Leuven (KUL), Campus Kortenberg.
authors.forename: K
authors.initials: K
authors.lastname: Vanwezer
authors.forename: G
authors.initials: G
authors.lastname: Pieters
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D018579:Patient Selection; D011570:Psychiatry / Q000379:methods* / Q000592:standards*; D016032:Randomized Controlled Trials as Topic; D015983:Selection Bias