title: Burdens of PBBs, PBDEs, and PCBs in tissues of the cancer patients in the e-waste disassembly sites in Zhejiang, China.
abstract: This study was conducted to explore the burdens of PBBs, PBDEs, and PCBs among cancer patients living in the e-waste disassembly sites. The contents of 23 PBB congeners, 12 PBDE congeners, and 27 PCB congeners in kidney, liver, and lung samples were measured by GC-MS. The results showed that low-brominated PBBs and PBB153 were the predominant congeners. PBDE47 were the most predominant PBDE congeners. PBDE209 were detected in > 70% of the samples, with geometric means ranging from 64.2 to 113.9 ng g(-1) lipid. Among the three subfamilies of PHAHs, PCB concentrations were the highest. The detected levels of PHAHs were in the same order of magnitude in the three tissues, which indicated that any of the three tissues could be the suitable indicator for assessing body burdens of PHAHs. PBB contents (181-192 ng g(-1) lipid) were obviously higher than those reported in the general USA population (3-8 ng g(-1) lipid). PBDE levels (174.1-182.3 ng g(-1) lipid) were comparable to those reported in the USA population, but significantly higher than those of the European population. PCBs levels were comparable to those of the European population. The high cancer incidence in the disassembly sites may be related to higher burdens of PBBs, PBDEs, and PCBs in tissues.
authors.affiliation: State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
authors.forename: Gaofeng
authors.initials: G
authors.lastname: Zhao
authors.forename: Zijian
authors.initials: Z
authors.lastname: Wang
authors.forename: Huaidong
authors.initials: H
authors.lastname: Zhou
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhao
mesh_terms: D001822:Body Burden; D002681:China; D004581:Electronics; D008401:Gas Chromatography-Mass Spectrometry; D055768:Halogenated Diphenyl Ethers / Q000493:pharmacokinetics*; D006801:Humans; D007220:Industrial Waste; D009369:Neoplasms / Q000378:metabolism*; D011075:Polybrominated Biphenyls / Q000493:pharmacokinetics*; D011078:Polychlorinated Biphenyls / Q000493:pharmacokinetics*
chemical_list: D055768:Halogenated Diphenyl Ethers; D007220:Industrial Waste; D011075:Polybrominated Biphenyls; C511295:2,2',4,4'-tetrabromodiphenyl ether; D011078:Polychlorinated Biphenyls