Prediction of neonatal acidemia by computer analysis of fetal heart rate and ST event signals.
OBJECTIVE
The objective of the study was to evaluate the accuracy of computer analysis of fetal heart rate (FHR) and ST event signals in prediction of neonatal acidemia.


METHODS
One hundred forty-eight FHR tracings were evaluated to identify red alerts provided by the system, based on automated analysis of FHR and ST event signals, and compared with the occurrence of umbilical artery acidemia (pH < or =7.05).


RESULTS
The presence of red alerts obtained sensitivity of 1.00 (95% confidence interval [CI], 0.56-1.00), specificity of 0.94 (95% CI, 0.89-0.97), positive predictive value (PPV) of 0.47 (95% CI, 0.22-0.72), negative predictive value (NPV) of 1 (95% CI, 0.96-1.00), positive likelihood ratio (PLR) of 17.6 (95% CI, 9.0-34.5), and negative likelihood ratio (NLR) of 0. When limiting analysis to red alerts that did not include ST data, sensitivity was 0.57 (95% CI, 0.20-0.88), specificity was 0.97 (95% CI, 0.92-0.99), PPV was 0.50 (95% CI, 0.17-0.82), NPV was 0.98 (95% CI, 0.93-0.99), PLR was 20.14 (95% CI, 6.3-64.2), and NLR was 0.44 (95% CI, 0.19-1.04).


CONCLUSIONS
Computer analysis of FHR and ST event signals provide higher accuracy in predicting neonatal academia.
Costa
Antonia
A
Departamento de Ginecologia e Obstetrícia, Hospital S. João, Universidade do Porto, Portugal. cosantonia@gmail.com
Ayres-de-Campos
Diogo
D
Costa
Fernanda
F
Santos
Cristina
C
Bernardes
Joao
J
D000138:Acidosis / Q000175:diagnosis* / Q000503:physiopathology*; D003936:Diagnosis, Computer-Assisted; D004562:Electrocardiography; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results