title: Neovascularisation and recurrence 2 years after varicose vein treatment for sapheno-femoral and great saphenous vein reflux: a comparison of surgery and endovenous laser ablation.
abstract: OBJECTIVE
  Neovascularisation is a major cause of recurrent varicosities following surgery. This prospective cohort study compares recurrence rates and the occurrence of neovascularisation following surgery or endovenous laser ablation (EVLA) for great saphenous vein reflux.
  
  
  METHODS
  118 consecutive patients (72 female, 46 male, median age 48 [range 32-68 years]), 129 limbs were reviewed at a median of 24 months (range 18-30) after surgery (n=60 limbs) or EVLA (n=69 limbs) for primary sapheno-femoral and GSV reflux. Varicose vein recurrence, ultrasound detected groin neovascularisation and patient satisfaction (visual analogue scale) were recorded.
  
  
  RESULTS
  Recurrence rates at 2 years were: surgery group 4/60 (6.6%; mid-thigh perforator n=2, residual GSV with neovascularisation n=2), EVLA group 5/69 (7%; GSV recanalisation n=3 (all received <50 J/cm laser energy), mid-thigh perforator n=1, new anterior saphenous vein reflux n=1) p=0.631. Neovascularisation was detected in 11/60 (18%) of the surgery group and 1/69 (1%) of the EVLA group, p=0.001. Patient satisfaction rates were 90% and 88% respectively (p=0.37).
  
  
  CONCLUSIONS
  Although the frequency of recurrent varicosities 2 years after surgery and EVLA was similar, neovascularisation, a predictor of future recurrence, was less common following EVLA. Further, current recommendations on delivering > or =70 J/cm laser energy should reduce recanalisation rates and recurrence after EVLA.
authors.affiliation: The Leeds Vascular Institute, General Infirmary at Leeds, Leeds LS1 3EX, UK.
authors.forename: N S
authors.initials: NS
authors.lastname: Theivacumar
authors.forename: R
authors.initials: R
authors.lastname: Darwood
authors.forename: M J
authors.initials: MJ
authors.lastname: Gough
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology*; D017060:Patient Satisfaction; D011446:Prospective Studies; D012008:Recurrence; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014648:Varicose Veins / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D014656:Vascular Surgical Procedures / Q000009:adverse effects*