title: [Intrascrotal rhabdomyosarcoma in adult: a case report].
abstract: The patient was a 34-year-old man presenting with the right intra-scrotal painless mass. With a diagnosis of right intrascrotal tumor, the patient underwent right high orchiectomy. The pathological diagnosis of pleomorphic rhabdomyosarcoma arisen from the right spermatic cord was made. Computed tomography revealed a single metastasis in the para-vena cava lymph node. Systemic chemotherapy with vincristine, actinomycin D, plus cyclophosphamide (VAC therapy), and etoposide plus cisplatin (EP therapy) were made according to Intergroup Rhabdomyosarcoma Study (IRS)-IV Regimen 45. But the chemotherapy was ineffective and a retoroperitoneal lymphadenectomy (RPLND) was therefore performed. After 3 months following RPLND, the tumor relapsed in a pelvic lymph node involved in right ureter and ileocaecal valve. Resection of the tumor with ileocaecum was performed and then intraoperative radiotherapy (15 Gy) against the tumor bed was performed to ensure the curative effects. After his recovery, he received a total of 6 courses of systemic chemotherapy consisting of vincristin, ifosphamide, etoposide (IRS-IV Regimen 47). The patient was rigorously followed up for 42 months after the final chemotherapy, with no tumor recurrence.
authors.affiliation: Department of Urology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Shimamoto
authors.forename: Nozomu
authors.initials: N
authors.lastname: Tanji
authors.forename: Akira
authors.initials: A
authors.lastname: Ozaw
authors.forename: Toyokazu
authors.initials: T
authors.lastname: Sasaki
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Ikeda
authors.forename: Tokuhiro
authors.initials: T
authors.lastname: Iseda
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yokoyama
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005500:Follow-Up Studies; D005834:Genital Neoplasms, Male / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D009919:Orchiectomy; D011859:Radiography; D018714:Radiotherapy, Adjuvant; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy*; D012611:Scrotum; D016896:Treatment Outcome