[Antioxidant properties of lactic acid bacteria--probiotic and yogurt strains].
Antioxidant properties of 14 strains of lactic acid bacteria were evaluated in vitro using FRAP assay, inhibition of luminol oxidation in Hb-H2O2 system and inhibition of NADPH-Fe2+ induced microsomal lipid peroxidation. All strains demonstrated high reducing properties, but only L. casei spp. (including L. casei 114001) and L. fermentum ME-3 revealed pronounced ability to suppress oxidation of luminol (by 43-65,8%) and microsomal lipid peroxidation (by 57,9-89,5%). Either L. casei 114001 (10(8) CFU suspended in physiological solution) or fermented dairy drink containing equivalent amount of L. casei 114001 were daily administered orally to male Wistar rats. Antioxidant capacity of blood plasma, liver and intestines of animals elevated while MDA content in blood plasma decreased.
Uskova
M A
MA
Kravchenko
L V
LV
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D003600:Cytosol / Q000201:enzymology / Q000378:metabolism; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000201:enzymology / Q000378:metabolism; D007778:Lactobacillus / Q000254:growth & development / Q000502:physiology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008054:Lipid Peroxides / Q000097:blood / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects; D019936:Probiotics / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism; D015014:Yogurt / Q000382:microbiology*
D000975:Antioxidants; D008054:Lipid Peroxides; D008315:Malondialdehyde; D013482:Superoxide Dismutase