Pro- and antioxidants in the central lymph in experimental chronic toxic hepatitis.
Using rat model of chronic toxic hepatitis we showed the involvement of the lymph system in the formation of the response to toxic liver damage consisting in deposition of LPO products in the central lymph and active involvement of antioxidants in their neutralization with redistribution of ceruloplasmin into lymph vessels against the background of reduced a-tocopherol content in the central lymph.
Borodin
Ju I
JI
Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Bashkirova
Ju V
JV
Lyubarsky
M S
MS
Kolpakov
M A
MA
D000475:Alkenes / Q000097:blood / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002570:Ceruloplasmin / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood / Q000378:metabolism*; D006521:Hepatitis, Chronic / Q000097:blood / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000502:physiology; D008196:Lymph / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D024502:alpha-Tocopherol / Q000097:blood / Q000378:metabolism
D000475:Alkenes; D000975:Antioxidants; D008315:Malondialdehyde; D002570:Ceruloplasmin; D024502:alpha-Tocopherol