title: [Comparison of 2-octyl cyanoacrylate adhesive and suturing for wound closure in the canine small bowel model].
abstract: OBJECTIVE
  We undertook this study to evaluate 2-octyl cyanoacrylate (2OCA) glue and suture for wound closure in the small bowel.
  
  
  METHODS
  This was a comparative and experimental study. Male and female domestic dogs (n = 10) underwent a 2.0-cm small bowel closure of two wounds. All of these had closure with 2OCA in the first wound. The controls (second wound in the same dog) were closed with suture. Four weeks later the wounds were observed to evaluate the repair.
  
  
  RESULTS
  Wound closure time and macrophage count were lower with the 2OCA glue than in the suture group.
  
  
  CONCLUSIONS
  2OCA glue has the strength to seal a small bowel wound. The inflammatory response to the glue is less than that of the suture at 4 weeks. These properties may make it a suitable material for replacing suture in a small bowel wound.
authors.affiliation: Departamento de Anatomía Humana y Laboratorio de Adiestramiento e Investigación Quirúrgica, Escuela Médico Militar, México, D. F., Mexico. coep67@hotmail.com
authors.forename: Oscar
authors.initials: O
authors.lastname: Escalante-Piña
authors.forename: Gabriela
authors.initials: G
authors.lastname: García-Nieto
authors.forename: Alma Rocío
authors.initials: AR
authors.lastname: Hernández-Jasso
authors.forename: Liliana
authors.initials: L
authors.lastname: Reyes-Castellanos
authors.forename: Mariana
authors.initials: M
authors.lastname: Flores-Aragón
authors.forename: Jose María
authors.initials: JM
authors.lastname: Rivera-Cruz
mesh_terms: D000818:Animals; D003487:Cyanoacrylates; D004285:Dogs; D005260:Female; D007421:Intestine, Small / Q000601:surgery*; D008297:Male; D013536:Suture Techniques; D014014:Tissue Adhesives; D014945:Wound Healing
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate