title: Nutrient-gene interactions in early life programming: leptin in breast milk prevents obesity later on in life.
abstract: Breast milk is practically the only food eaten during the first months of life in fully breastfed infants and it is assumed to match the nutritional needs during these first months of postnatal life. Breastfeeding compared with infant formula feeding confers protection against several metabolic and physiological changes later on in life and, particularly, against obesity and related medical complications. Recent data from our laboratory, identifying leptin as the first specific compound responsible for these beneficial effects, are reviewed and discussed.
authors.affiliation: Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of the Balearic Islands (UIB) and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Palma de Mallorca, Spain. andreu.palou@uib.es
authors.forename: Andreu
authors.initials: A
authors.lastname: Palou
authors.forename: Juana
authors.initials: J
authors.lastname: Sánchez
authors.forename: Catalina
authors.initials: C
authors.lastname: Picó
mesh_terms: D000328:Adult; D000818:Animals; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena / Q000235:genetics / Q000502:physiology*; D007231:Infant, Newborn; D020738:Leptin / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D039382:Maternal Nutritional Physiological Phenomena / Q000235:genetics / Q000502:physiology*; D009765:Obesity / Q000235:genetics / Q000517:prevention & control*; D051381:Rats
chemical_list: D020738:Leptin