Linear IgA bullous dermatosis induced by interferon-alpha 2a.
Linear Ig A bullous dermatosis (LABD) is an acquired autoimmune subepidermal blistering disorder with linear deposits of IgA along the basement membrane zone. Its cause is unclear, although it appears to have an immune-mediated basis. Idiopathic, systemic disorder-related, and rarely drug-induced forms of LABD have been described. We describe a case of LABD associated with interferon-alpha 2A used for the treatment of Kaposi's sarcoma.
Kocyigit
P
P
Department of Dermatology, Ankara University Medical School, Ankara, Turkey. kocyigit@medicine.ankara.edu.tr
Akay
B N
BN
Karaosmanoglu
N
N
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D011994:Recombinant Proteins; D012514:Sarcoma, Kaposi / Q000188:drug therapy; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000276:immunology
D000970:Antineoplastic Agents; D007070:Immunoglobulin A; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins