title: Specific features of the immune response in old recipient mice to cell therapy.
abstract: Implantation of somatic cells from autopsy specimens (15-18 weeks gestation) had a modulatory effect on immunogenesis in old mice. Activation of the immune system in recipient animals after administration of somatic cells reflects a multistage influence of test preparation. The observed changes were reversible. A progressive decrease in activation of the immune system in recipient mice was not accompanied by the development of pathological changes. Repeated implantation was required to maintain these processes.
authors.affiliation: Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia. morfolhum@mail.ru
authors.forename: Z S
authors.initials: ZS
authors.lastname: Khlystova
authors.forename: I I
authors.initials: II
authors.lastname: Kalinina
authors.forename: S P
authors.initials: SP
authors.lastname: Shmeleva
authors.forename: L V
authors.initials: LV
authors.lastname: Kuznetsova
authors.forename: T A
authors.initials: TA
authors.lastname: Minina
authors.forename: O I
authors.initials: OI
authors.lastname: Tokareva
mesh_terms: D000818:Animals; D017690:Cell Transplantation; D051379:Mice; D008808:Mice, Inbred CBA