[Magnetic oesophageal sphincter for the treatment of gastro-oesophageal reflux disease: results of a prospective clinical trial].
The authors report the preliminary results of a prospective study in 30 patients with gastro-oesophageal reflux disease. The aim was to assess the efficacy of an-original device designed to augment the lower oesophageal sphincter barrier using magnetic force. The device was placed laparoscopically around the oesophagogastric junction, at the level of the z line identified by intraoperative endoscopy. Transient dysphagia not requiring any treatment was recorded in 45% of patients. At 3 months postoperatively, the GORD-HRQL score was fond to be significantly decreased from 24.4 to 2.2 (p < 0.001) and the DeMeester score was normalised in 80% of patients. At one year follow-up, 100% of patients were off proton pump inhibitors, and 70% of them had a normal DeMeester score. All patients preserved the ability to belch.
Nencioni
Marco
M
Sezione di Chirurgia Generale, Dipartimento di Scienze Medico-Chirurgiche, Università di Milano, IRCCS Policlinico San Donato, San Donato Milanese, Milano.
Asti
Emanuele
E
Saino
Greta
G
Bona
Davide
D
Pallotta
Stefano
S
Laface
Letizia
L
Bonavina
Luigi
L
D000328:Adult; D003680:Deglutition Disorders / Q000209:etiology; D050782:Esophageal pH Monitoring; D004943:Esophagogastric Junction / Q000601:surgery*; D004945:Esophagoscopy; D005260:Female; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D008280:Magnetics / Q000295:instrumentation*; D008297:Male; D008365:Manometry; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D016896:Treatment Outcome