title: [The influence of hypersensitivity to nickel, chrome and cobalt on the process of fracture healing in patients treated operatively by stable osteosynthesis].
abstract: The aim of the study was to evaluate the frequency of occurrence of the hypersensitivity to nickel, chrome and cobalt in patients with longbone fractures. Two groups of patients were compared. The first group was composed of those treated operatively by stable osteosynthesis with the use of metal implants. The control group consisted of patients who have never been operated. Additionally, the influence of recognized hypersensitivity on the process of fracture healing was estimated. The study group consisted of 80 and the control group of 65 patients. All patients were patch tested with metal salts. The correlation was sought between hypersensitivity to metal in the study group, and incidence of complications relating to fracture healing. There was no significant difference observed both in frequency of occurrence of hypersensitivity to nickel, chrome and cobalt among patients treated operatively, and those treated conservatively, as well. There was no correlation between occurrence of hypersensitivity to the ions of metals, and complications in the process of fracture healing.
authors.affiliation: Katedra i Klinika Ortopedii i Traumatologii, Pomorska Akademia Medyczna w Szczecinie. konrad_dobiecki@o2.pl
authors.forename: Konrad
authors.initials: K
authors.lastname: Dobiecki
authors.forename: Paweł
authors.initials: P
authors.lastname: Zietek
authors.forename: Lukasz
authors.initials: L
authors.lastname: Kołodziej
authors.forename: Marek
authors.initials: M
authors.lastname: Brzosko
authors.forename: Andrzej
authors.initials: A
authors.lastname: Bohatyrewicz
authors.forename: Michał
authors.initials: M
authors.lastname: Kedzierski
mesh_terms: D000328:Adult; D000368:Aged; D015984:Causality; D002857:Chromium / Q000009:adverse effects*; D003035:Cobalt / Q000009:adverse effects*; D015897:Comorbidity; D003877:Dermatitis, Contact / Q000453:epidemiology* / Q000209:etiology; D005593:Fracture Fixation, Internal / Q000009:adverse effects / Q000706:statistics & numerical data; D050723:Fractures, Bone / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D016268:Internal Fixators / Q000009:adverse effects*; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D010328:Patch Tests / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D011475:Prosthesis Failure; D055815:Young Adult
chemical_list: D002857:Chromium; D003035:Cobalt; D009532:Nickel