title: Helicobacter pylori infection is associated with low serum ferritin levels in Israeli Arab children: a seroepidemiologic study.
abstract: We examined the association between Helicobacter pylori seropositivity and low ferritin levels in sera of 509 Israeli Arab children aged 1 to 19 years. Serum ferritin levels were measured using the immunoturbidity assay. ELISA was used to detect serum IgG antibodies to H pylori and IgG antibodies to H pylori CagA strains. Low ferritin level was found between 14.5% and 8.6% of the H pylori seropositive and seronegative participants, respectively (P = 0.035). A trend for a higher frequency of low ferritin was detected among H pylori-CagA seropositive children. Multivariate analysis showed an increased frequency of low ferritin only among children younger than or equal to 5 years: adjusted OR 4.62 (95% CI 1.53-13.99) P = 0.007.
authors.affiliation: Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Khitam
authors.initials: K
authors.lastname: Muhsen
authors.forename: Mira
authors.initials: M
authors.lastname: Barak
authors.forename: Luba
authors.initials: L
authors.lastname: Shifnaidel
authors.forename: Avishag
authors.initials: A
authors.lastname: Nir
authors.forename: Ravit
authors.initials: R
authors.lastname: Bassal
authors.forename: Dani
authors.initials: D
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000150:complications* / Q000208:ethnology; D018912:Arabs; D002648:Child; D002675:Child, Preschool; D005260:Female; D005293:Ferritins / Q000097:blood* / Q000276:immunology; D016481:Helicobacter Infections / Q000097:blood / Q000150:complications* / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D007557:Israel / Q000453:epidemiology; D008297:Male; D015999:Multivariate Analysis; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G; D005293:Ferritins