[Association Budd Chiari syndrome, antiphospholipid syndrome and Grave's disease].
BACKGROUND
Antiphospholipid syndrome is revealed by Budd Chiari syndrome in 5% of the cases. Antiphospholipid syndrome is characterized by venous or arterial thrombosis, foetal loss and positivity of antiphospholipid antibodies, namely lupus anticoagulant, anticardiolipin antibodies and anti-beta2-glycoprotein I. Anticardiolipin antibodies was reported in auto-immune thyroid disorders, particularly in Grave's disease. Antiphospholipid syndrome associated to Grave's disease was reported in only three cases.


OBJECTIVE
To describe a case report of association of Grave's disease and antiphospholipid syndrome.


METHODS
We report the first case of Grave's disease associated with antiphospholipid syndrome, revealed by Budd Chiari syndrome.


CONCLUSIONS
Our observation is particular by the fact that it is about a patient presenting a Grave's disease associated with antiphospholipid syndrome revealed by Budd Chiari syndrome. This triple association has never been reported in literature. Although association between antiphospholipid syndrome and Grave's disease was previously described, further studies evaluating the coexistence of these two affections in the same patient would be useful.
Mouelhi
Leila
L
Service de Gastro-entérologie, Hôpital Charles Nicolle, Tunis.
Chaieb
Mouna
M
Debbeche
Radhouane
R
Salem
Mohamed
M
Sfar
Imene
I
Trabelsi
Sinda
S
Gorgi
Yosr
Y
Najjar
Taoufik
T
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D006502:Budd-Chiari Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D017809:Fatal Outcome; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology; D008297:Male
D017153:Antibodies, Anticardiolipin; D015415:Biomarkers; D007155:Immunologic Factors