[A retrospective study of 339 ICSI cycles: assesment of the two first years of activity of the Assisted Reproductive Technology Center of Aziza Othmana Hospital].
BACKGROUND
Intracytoplasmic sperm injection (ICSI) is a micromanipulation-assisted fertilization, whereby one spermatozoon is injected into the oocyte cytoplasm. Initially, ICSI was the treatment of choice for male factor infertility. However, because of the high fertilization and pregnancy rates achieved with this technique, the scope of the procedure has been widened to include couples with other causes of infertility.


OBJECTIVE
The aim of this study was to study the progression of the activity of the assisted reproductive technology's center of Aziza Othmana's Hospital and the ICSI results during the first two years.


METHODS
Our study included 269 infertile couples who underwent 339 ICSI cycles between 1st May 2001 and 30 April 2003. Cycles with no oocytes obtained at the follicular aspiration and women aged over 40 years were excluded from this study.


RESULTS
The number of ICSI cycles progressed in our center: 150 ICSI cycles in the 1st year, 189 ICSI cycles in the 2nd year. The mean number of picked-up oocytes was 8,8 +/- 5,6. The fertilization rate was 62%. The mean number of transferred embryos was 3,1 +/- 1,5. The pregnancy rate per transfer was 32,4%. The miscarriage rate was 28,4%. The take home baby rate was 67,9%.


CONCLUSIONS
The number of couples undergoing ICSI cycles in our center is increasing. The fertilization rates and pregnancy rates in our center are similar to those published in the literature.
Fourati
Selima
S
Unité d'AMP, service de gynécologie obstétrique, Hôpital Aziza Othmana, La Kasba, Tunis.
Chaker
Anis
A
Fadhlaoui
Anis
A
Ben Hamida
Abdelmajid
A
Kacem
Olfa
O
Merdassi
Ghaya
G
Kdous
Moez
M
Ferchiou
Monia
M
Zhioua
Fethi
F
Meriah
Sadok
S
Zhioua
Amel
A
D000022:Abortion, Spontaneous / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000706:statistics & numerical data* / Q000639:trends; D014416:Tunisia / Q000453:epidemiology