Effects of lecithin on the mechanical properties of hydroxypropylmethylcellulose free films.
The effects of the biocompatible surfactant lecithin (a pigment-stabilizing agent) on the mechanical properties of free hydroxypropylmethylcellulose films were evaluated. The film thickness and the characteristics of the deformation curve were not altered relevantly by the incorporation of lecithin. The deformation force decreased markedly when the lecithin content of the film exceeded 5%.
Bajdik
J
J
Department of Pharmaceutical Technology, University of Szeged, Szeged, Hungary.
Pintye-Hódi
K
K
D002626:Chemistry, Pharmaceutical; D005079:Excipients; D065347:Hypromellose Derivatives; D054709:Lecithins / Q000737:chemistry*; D008567:Membranes, Artificial; D008747:Methylcellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry*; D013608:Tablets, Enteric-Coated
D005079:Excipients; D054709:Lecithins; D008567:Membranes, Artificial; D013501:Surface-Active Agents; D013608:Tablets, Enteric-Coated; D065347:Hypromellose Derivatives; D008747:Methylcellulose