Antitumor and immunomodulating effects of a fragment of HL-60 cell differentiation factor in mice with lewis pulmonary carcinoma.
A six-member HLDF6 peptide, fragment of HL-60 cell differentiation factor, exhibited antimetastatic and immunomodulating effects.
Sysoeva
G M
GM
Vector State Center of Virology and Biotechnology, Federal Service for Surveillance in the Sphere of Consumer Rights Protection and Human Well-Being, Koltsovo, Novosibirsk Region, Russia. sysoeva50@mail.ru
Fadina
V A
VA
Danilenko
E D
ED
Samukov
V V
VV
Kostanyan
I A
IA
Masycheva
V I
VI
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D018827:Carcinoma, Lewis Lung; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D015850:Interleukin-6 / Q000494:pharmacology*; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D009363:Neoplasm Proteins / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology
D000970:Antineoplastic Agents; D015850:Interleukin-6; D009363:Neoplasm Proteins; D010455:Peptides; C091149:cell differentiation factor 8.2-kDa