title: Effects of autologous bone marrow cells on apoptosis and regeneration of non-healing autoimmune gastric ulcers.
abstract: The effects of cultured autologous bone marrow multipotent mesenchymal stromal cells on apoptosis and healing processes were studied on the model of non-healing gastric ulcers in rats. Bone marrow multipotent mesenchymal stromal cells inhibited apoptosis in epitheliocytes of the gastric mucosa and stimulated ulcer healing.
authors.affiliation: Institute of Transplantology and Artificial Organs, Federal Agency of Medical Technologies, Russia. illak@mail.ru
authors.forename: M B
authors.initials: MB
authors.lastname: Askarov
authors.forename: O F
authors.initials: OF
authors.lastname: Vostrikova
authors.forename: N N
authors.initials: NN
authors.lastname: Vorobjova
authors.forename: N A
authors.initials: NA
authors.lastname: Onishenko
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D005753:Gastric Mucosa / Q000166:cytology; D007371:Interferon-gamma / Q000097:blood; D016753:Interleukin-10 / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D008233:Lymphotoxin-alpha / Q000097:blood; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D039902:Multipotent Stem Cells / Q000166:cytology*; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000097:blood / Q000628:therapy*; D017154:Stromal Cells / Q000166:cytology*; D014182:Transplantation, Autologous / Q000379:methods*; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D053583:Interleukin-1beta; D008233:Lymphotoxin-alpha; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D015847:Interleukin-4; D007371:Interferon-gamma