The NGF point-injection for treatment of the sound-perceiving nerve deafness and tinnitus in 68 cases.
OBJECTIVE
To observe the therapeutic effects of the point-injection with nerve growth factor (NGF) for the sound-perceiving nerve deafness and tinnitus.


METHODS
The 140 cases in this series were randomly divided into a treatment group of 68 cases treated by NGF injection at the points of Yifeng (TE 17) and Wangu (GB 12), and a control group of 72 cases orally taking Xibiling and adenosine triphosphate (ATP) and intramuscular injection with VB1 and VB12.


RESULTS
The total effective rate was 78.6% in the treatment group and 31.8% in the control group, with significant difference between the two groups (P<0.05).


CONCLUSIONS
For treating nervous deafness and tinnitus, NGF point-injection may show good therapeutic effects, but inversely proportional to the illness course, age and the extent of hypoacusis.
Zhou
Feng
F
Guangzhou Otorhinolaryngology and the Head-Neck Surgery Hospital, Guangzhou 510620, China.
Wu
Ping
P
Wang
Li
L
Wang
Hai-tao
HT
Zhang
Shao-bin
SB
Lin
Yi
Y
Zhong
Hui
H
Chen
Yan-Hua
YH
D015669:Acupuncture Points; D000255:Adenosine Triphosphate / Q000008:administration & dosage; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D003638:Deafness / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D020932:Nerve Growth Factor / Q000008:administration & dosage*; D014012:Tinnitus / Q000188:drug therapy*; D055815:Young Adult
D004365:Drugs, Chinese Herbal; D000255:Adenosine Triphosphate; D020932:Nerve Growth Factor