A covalently linked phenanthridine-ruthenium(II) complex as a RNA probe.
A phenanthridine derivative covalently linked to a ruthenium complex yields an imaging probe whose fluorescence intensity and lifetime change substantially in the presence of RNA.
O'Connor
Naphtali A
NA
Department of Chemistry, Lehman College of The City University of New York, Bronx, NY 10468, USA. naphtali.oconnor@lehman.cuny.edu
Stevens
Nathan
N
Samaroo
Diana
D
Solomon
Marissa R
MR
Martí
Angel A
AA
Dyer
Joanne
J
Vishwasrao
Harshad
H
Akins
Daniel L
DL
Kandel
Eric R
ER
Turro
Nicholas J
NJ
D000818:Animals; D001943:Breast Neoplasms / Q000378:metabolism; D005456:Fluorescent Dyes / Q000138:chemical synthesis; D008856:Microscopy, Fluorescence; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D010617:Phenanthridines / Q000138:chemical synthesis*; D015347:RNA Probes / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry*
D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D010617:Phenanthridines; D015347:RNA Probes; D012428:Ruthenium