title: Practical experience with the treatment of recipient mares with a non-steroidal anti-inflammatory drug in an equine embryo transfer programme.
abstract: As part of a commercial embryo transfer programme, 20 embryos were transferred to spontaneously synchronous or synchronized recipient mares. In 14 cases, embryo recipients were treated with non-steroidal anti-inflammatory drugs (NSAID), receiving flunixin meglumine i.v. at the time of transfer and vedaprofen orally twice a day on the 3 days after embryo transfer, while six embryos were transferred to untreated mares that served as controls. Out of the 14 recipient mares treated with NSAID, 11 (79%) were pregnant at 6-8 days after transfer and in 10 mares, the pregnancy was continued. From the six untreated recipients, only one became pregnant but underwent early embryonic death between day 14 and 35 after ovulation. In conclusion, pregnancy rate in NSAID-treated recipients is higher than that in untreated recipients and above reported average values, indicating that treatment of recipient mares with NSAID helps to increase pregnancy rates after transcervical transfer and can be recommended for equine embryo transfer.
authors.affiliation: Graf Lehndorff Institute for Equine Sciences, Brandenburg State Stud, Neustadt (Dosse), Germany.
authors.forename: P
authors.initials: P
authors.lastname: Koblischke
authors.forename: S
authors.initials: S
authors.lastname: Budik
authors.forename: J
authors.initials: J
authors.lastname: Müller
authors.forename: C
authors.initials: C
authors.lastname: Aurich
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D003002:Clonixin / Q000031:analogs & derivatives* / Q000494:pharmacology; D004624:Embryo Transfer / Q000662:veterinary*; D005260:Female; D006736:Horses / Q000502:physiology*; D009281:Naphthalenes / Q000494:pharmacology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011270:Pregnancy, Animal / Q000187:drug effects; D011422:Propionates / Q000494:pharmacology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009281:Naphthalenes; D011422:Propionates; C014558:flunixin meglumine; C121784:2-(4-cyclohexyl-1-naphthalenyl)propanoic acid; D003002:Clonixin