Using HIV resistance tests in clinical practice.
Genotypic resistance testing is now a standard of care in HIV management. Although there are clear, published guidelines to recommend the appropriate use of these tests, clinicians and scientists still struggle to determine the optimal use of resistance tests given the finite budgets and time constraints under which they work. In this article we discuss some 'real-life' clinical situations and aim to provide a useful insight into when and where genotypic resistance testing can be optimally applied in the management of HIV-positive adults.
Taylor
Stephen
S
Directorate of Sexual Medicine and HIV, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Birmingham, UK. steve.taylor@heartofengland.nhs.uk
Jayasuriya
Ashini
A
Smit
Erasmus
E
D000328:Adult; D019380:Anti-HIV Agents / Q000494:pharmacology*; D005260:Female; D005838:Genotype; D017408:Guidelines as Topic; D006678:HIV / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D015658:HIV Infections / Q000821:virology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data*
D019380:Anti-HIV Agents