[The genetic variability and genotyping of tick-borne encephalitis virus with deoxyoligonucleotide probes].
A panel of genotype-specific molecular probes has been designed, which is used to indicate and differentiate tickborne encephalitis (TBE) virus. It assesses the individual genetic structure of each strain since the targets for the probes are the variable sequences of all 10 virus genes, which are specific for each of three genotypes. The molecular nucleic acid hybridization by means of the panel was used to study 273 TBE virus strains. Isolated from a Eurasian area; along with the representatives of three genotypes, the virus strains, the genomic structures of which do not fit in the established concept on three genotypes, circulate in Eastern Siberia.
Demina
T V
TV
Dzhioev
Iu P
IuP
Verkhozina
M M
MM
Kozlova
I V
IV
Tkachev
S E
SE
Dorozhchenko
E K
EK
Lisak
O V
OV
Zlobin
V I
VI
D000818:Animals; D004669:Encephalitis Viruses, Tick-Borne / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D014644:Genetic Variation; D006801:Humans; D009693:Nucleic Acid Hybridization / Q000379:methods*; D015345:Oligonucleotide Probes / Q000235:genetics*; D010802:Phylogeny
D015345:Oligonucleotide Probes