Synthetically useful Brønsted acid-promoted arylbenzyl ether --> o-benzylphenol rearrangements.
Camphorsulfonic acid in warm fluorobenzene facilitates the ortho rearrangement of (alkoxy-substituted) benzyl ethers of 1-(O-methyl)-2-nitroresorcinols to the corresponding o-(alkoxy-substituted) arylmethylnitrophenols. The substrate phenolic ethers are prepared by ultrasound-promoted arylmethylation of the appropriate 1-alkoxy-substituted 2-nitroresorcinol.
Luzzio
Frederick A
FA
Department of Chemistry, University of Louisville, 2320 South Brook Street, Louisville, Kentucky 40292, USA. faluzz01@gwise.louisville.edu
Chen
Juan
J