title: Warfarin-induced intracerebral hemorrhage associated with microbleeds.
abstract: BACKGROUND
  Microbleeds (MBs), proposed as a biomarker for microangiopathy, have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear.
  
  
  METHODS
  We describe two patients who developed warfarin-induced ICH at the site of MBs documented in previous MRI.
  
  
  CONCLUSIONS
  The presence of MBs might increase the risk of ICH after warfarin use in ischemic stroke patients. A large cohort study is required to confirm the relationship of MBs with warfarin-induced ICH.
authors.affiliation: Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Gha-Hyun
authors.initials: GH
authors.lastname: Lee
authors.forename: Sun U
authors.initials: SU
authors.lastname: Kwon
authors.forename: Dong-Wha
authors.initials: DW
authors.lastname: Kang