A facile route to aryl boronates: room-temperature, copper-catalyzed borylation of aryl halides with alkoxy diboron reagents.
A simple but effective copper-catalyzed borylation of aryl halides, including electron-rich and sterically hindered aryl bromides, with alkoxy diboron reagents occurs under mild conditions (see scheme). Preliminary DFT studies of the mechanism suggest that sigma-bond metathesis between a copper-boryl intermediate and the aryl halide generates the aryl boronate product.
Kleeberg
Christian
C
Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
Dang
Li
L
Lin
Zhenyang
Z
Marder
Todd B
TB