Expression of growth factors in endotheliocytes in vascular malformations.
The expression of growth factors and proliferation of endotheliocytes in vascular malformations were studied by immunohistochemical methods. The detected specific features of growth factor expression in the endothelium of venous and arteriovenous malformations seem to reflect the differences in the pathogenesis of these formations. High proliferative activity of the endothelium in angiodysplasias of both types can underlie the disease relapsing.
Pavlov
K A
KA
Department of Pathological Anatomy, A. V. Vishnevskii Institute of Surgery, Moscow, Russia. pavlovka@ixv.comcor.ru
Dubova
E A
EA
Shchyogolev
A I
AI
Mishnyov
O D
OD
D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000378:metabolism* / Q000473:pathology; D042783:Endothelial Cells / Q000378:metabolism* / Q000473:pathology; D004730:Endothelium, Vascular / Q000378:metabolism* / Q000473:pathology; D005260:Female; D005346:Fibroblast Growth Factors / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D016212:Transforming Growth Factor beta / Q000378:metabolism; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism; D042561:Vascular Endothelial Growth Factor B / Q000378:metabolism; D042582:Vascular Endothelial Growth Factor C / Q000378:metabolism; D042643:Vascular Endothelial Growth Factor D / Q000378:metabolism; D054079:Vascular Malformations / Q000378:metabolism* / Q000473:pathology; D055815:Young Adult
D016212:Transforming Growth Factor beta; D042461:Vascular Endothelial Growth Factor A; D042561:Vascular Endothelial Growth Factor B; D042582:Vascular Endothelial Growth Factor C; D042643:Vascular Endothelial Growth Factor D; D005346:Fibroblast Growth Factors