Environmental adaptation of Francisella tularensis.
Concerns over weaponizable bacteria have recently prompted considerable interest in Francisella tularensis (Ft). In addition to its potential illicit use, Ft occurs naturally in diverse ecological niches including mammals, arthropods, and fresh water protozoans. Here we review the current knowledge of Ft adaptation which has ramifications for both basic and applied research.
Hazlett
Karsten R O
KR
Center for Immunology and Microbial Disease, Albany Medical College, 47 New Scotland Avenue, Albany, NY 12208, USA. hazlett@mail.amc.edu
Cirillo
Kerry A
KA
D000222:Adaptation, Physiological; D000818:Animals; D005604:Francisella tularensis / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans