Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).
The first International Caenorhabditis elegans Experiment (ICE-First) was carried out using a Russian Soyuz spacecraft from April 19-30, 2004. This experiment was a part of the program of the DELTA (Dutch Expedition for Life science Technology and Atmospheric research) mission, and the space agencies that participate in the International Space Station (ISS) program formed international research teams. A Japanese research team that conducted by Japan aerospace Exploration Agency (JAXA) investigated the following aspects of the organism: (1) whether meiotic chromosomal dynamics and apoptosis in the germ cells were normal under microgravity conditions, (2) the effect of the space flight on muscle cell development, and (3) the effect of the space flight on protein aggregation. In this article, we summarize the results of these biochemical and molecular biological analyses.
Higashibata
Akira
A
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, JAPAN.
Higashitani
Atsushi
A
Adachi
Ryota
R
Kagawa
Hiroaki
H
Honda
Shuji
S
Honda
Yoko
Y
Higashitani
Nahoko
N
Sasagawa
Yohei
Y
Miyazawa
Yutaka
Y
Szewczyk
Nathaniel J
NJ
Conley
Catharine A
CA
Fujimoto
Nobuyoshi
N
Fukui
Keiji
K
Shimazu
Toru
T
Kuriyama
Kana
K
Ishioka
Noriaki
N