title: The use of the artificial dermis (Integra) in combination with vacuum assisted closure for reconstruction of an extensive burn scar--a case report.
abstract: The artificial dermis Integra (Ethicon, Johnson & Johnson Medical, Norderstedt, Germany) is widely used in the treatment of excessive burn injuries. It is also used in reconstructive surgery when large soft-tissue defects could not be covered with local or free flaps. In this article a 25-year old patient who presented with an early childhood burn of the trunk and lower extremity was treated with Integra in combination with the vacuum assisted closure (V.A.C., KCI, Texas, U.S.A.) and split thickness skin grafting. The combination of the artificial dermal substitute with negative pressure therapy has lead to a complete healing of Integra and the skin graft. During the whole treatment sterile wound conditions were present and time-consuming dressing changes could be prevented. Hospital stay was shortened because the patient could be treated as an outpatient with an ambulant vacuum assisted closure device.
authors.affiliation: Department of Plastic and Hand Surgery, University Hospital Erlangen, Krankenhausstrasse 12, D-91054 Erlangen, Germany. Mareike.Leffler@uk-erlangen.de
authors.forename: M
authors.initials: M
authors.lastname: Leffler
authors.forename: R E
authors.initials: RE
authors.lastname: Horch
authors.forename: A
authors.initials: A
authors.lastname: Dragu
authors.forename: A D
authors.initials: AD
authors.lastname: Bach
mesh_terms: D000328:Adult; D002056:Burns / Q000601:surgery*; D002081:Buttocks; D002809:Chondroitin Sulfates; D002921:Cicatrix / Q000601:surgery*; D003094:Collagen; D006801:Humans; D007866:Leg; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation; D013909:Thorax; D014618:Vacuum
chemical_list: C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen