title: Effects of monochromatic aberration on visual acuity using adaptive optics.
abstract: OBJECTIVE
  To investigate the effect on visual acuity of correcting specific Zernike aberrations.
  
  
  METHODS
  Visual acuity was tested for 12 young subjects using a Freiburg Acuity Test procedure under conditions with wavefront aberrations corrected by an adaptive optics system. The adaptive optics system consists of a Hartmann-Shack wavefront sensor, a deformable mirror, relevant optical channels and closed loop control system. Five aberration correction paradigms were used to correct different Zernike terms.
  
  
  RESULTS
  With the second order aberration fully corrected, a significant improvement in visual acuity was observed (0.056 logMAR, t = 2.79, p = 0.018). Further correction of third order Zernike aberrations resulted in an additional improvement of 0.041 logMAR (t = 2.63, p = 0.023). But an additional correction of spherical aberration did not produce a significant increase in visual acuity (t = 1.10, NS). Full correction of aberrations achieved the best visual acuity with an improvement of 0.022 logMAR (t = 2.46, p = 0.032). The visual acuity was found to increase with the root mean square values of the residual aberrations with a linear relationship (r = 0.63, p < 0.0001).
  
  
  CONCLUSIONS
  Correction of monochromatic wavefront aberrations improves visual acuity for normal eyes and the improvement of visual acuity is proportional to the change of root mean square of wavefront aberrations.
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Shiming
authors.initials: S
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Xiong
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Dai
authors.forename: Lixia
authors.initials: L
authors.lastname: Xue
authors.forename: Haoxin
authors.initials: H
authors.lastname: Zhao
authors.forename: Wenhan
authors.initials: W
authors.lastname: Jiang
authors.forename: Yudong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ji C
authors.initials: JC
authors.lastname: He
mesh_terms: D000328:Adult; D019781:Corneal Topography; D005260:Female; D006801:Humans; D008297:Male; D055096:Optical Devices; D010775:Photic Stimulation / Q000295:instrumentation / Q000379:methods; D012030:Refractive Errors / Q000175:diagnosis / Q000503:physiopathology* / Q000534:rehabilitation*; D014792:Visual Acuity; D055815:Young Adult