title: Paucimannose N-glycans in Caenorhabditis elegans and Drosophila melanogaster.
abstract: There is a rich diversity of paucimannose N-glycans in worms and flies, and these may play a role in the survival of these organisms. Although paucimannose N-glycans are not expressed in vertebrates, complex N-glycans may take over some of the functions of paucimannose N-glycans. Identification of the target proteins of beta-1,2-N-acetylglucosaminyltransferase I (GnTI) in worms and flies and elucidation of their functions may thus lead to a better understanding of the role of GnTI-dependent glycoproteins in the survival/longevity of both invertebrates and vertebrates.
authors.affiliation: Molecular Structure and Function Program, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto Ont, Canada M5G 1X8. harry@sickkids.ca
authors.forename: Harry
authors.initials: H
authors.lastname: Schachter
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000378:metabolism*; D002240:Carbohydrate Sequence; D004331:Drosophila melanogaster / Q000235:genetics / Q000378:metabolism*; D008136:Longevity / Q000502:physiology; D008954:Models, Biological; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011134:Polysaccharides