Intracranial compound odontome.
An exceedingly rare case of an extragnathic odontome is described arising within the brain. A 10-year-old boy complained of progressive frontal headache for 5 years. Axial computerized tomography the head revealed a solid, calcified lesion with well-defined borders localized in the sellar and suprasellar region composed of multiple calcified structures resembling teeth. The diagnosis was compound odontome. Physical examination and blood analysis revealed hypopituitarism. The patient was submitted for radical tumour resection. He developed persistent diabetes insipidus, hypothyroidism and adrenal insufficiency for which appropriate replacement therapy has been necessary. This case demonstrates that an odontogenic lesion may arise in brain tissues due to the embryological relationship between primordial stomodeum and Rathke's pouch. Its development could be associated with endocrine disturbances.
de Faria
Paulo Rogério
PR
Departamento de Morfologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil.
Cardoso
Sérgio Vitorino
SV
Rocha
Ademir
A
Gomes
Débora Cristiane
DC
de Castro
Samuel Caputo
SC
Loyola
Adriano Mota
AM
D001927:Brain Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002648:Child; D002828:Choristoma / Q000473:pathology* / Q000601:surgery; D003397:Craniopharyngioma / Q000473:pathology / Q000601:surgery; D003919:Diabetes Insipidus / Q000209:etiology / Q000628:therapy; D006222:Hamartoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology / Q000628:therapy; D008297:Male; D009808:Odontogenic Tumors / Q000473:pathology* / Q000601:surgery; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery; D014071:Tooth Abnormalities; D016896:Treatment Outcome