Clinical efficiency of a natural resin fluoride varnish (Shellac F) in reducing dentin hypersensitivity.
Previous in vitro permeability and scanning electron microscopic studies have demonstrated the effectiveness of a new natural based-resin varnish (Shellac F) in dentin permeability reduction and effective tubule occlusion. The aim of this randomized double-blind, controlled, split mouth 8-week clinical study was to evaluate the efficiency of Shellac F in reducing dentin hypersensitivity. Ten patients (eight women: two men) completed the study. A quadrant including at least one hypersensitive tooth (Visual Analog Scale - VAS = 15 mm to air blast) was considered as a unit and randomly assigned to different groups for Shellac F, Duraphat, Isodan. Three applications of each material were completed at days 0, 1 and 7. The subjective response was assessed by tactile and thermal/evaporative methods. Data were collected at baseline and after the first application, at 15 min, 1, 7, 14, 28 and 56 days. Analysis was based on Kruskall-Wallis test, Wilcoxon signed rank test and the method of the least square means. No statistically significant difference was noted between Shellac F and the two control materials. Regardless of the type of stimulus, Shellac F showed significant immediate and progressive continuous efficiency in reducing dentin hypersensitivity until 56 days (VAS of 14 +/- 12 mm and provoking pain force of 89 +/- 12 cN, respectively, compared with 38 +/- 23 mm and 41 +/- 10 cN at baseline), corresponding to a highly effective relief dentin hypersensitivity. Shellac F reduced dentin hypersensitivity and did not differ from the two desensitizing agents used as controls.
Hoang-Dao
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BT
Laboratoire IMEB, Faculté d'Odontologie, Université de la Méditerranée, Marseille, France.
Hoang-Tu
H
H
Tran-Thi
N-N
NN
Koubi
G
G
Camps
J
J
About
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I
D000328:Adult; D002327:Cariostatic Agents / Q000627:therapeutic use; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003806:Dentin Permeability / Q000187:drug effects*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008689:Methacrylates; D008875:Middle Aged; D009566:Nitrates; D012969:Sodium Fluoride; D016896:Treatment Outcome; D055815:Young Adult
D002327:Cariostatic Agents; D057133:Dentin Desensitizing Agents; D005460:Fluorides, Topical; C473099:Isodan; D008689:Methacrylates; D009566:Nitrates; C531968:shellac F; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride