title: InterMap3D: predicting and visualizing co-evolving protein residues.
abstract: CONCLUSIONS
  InterMap3D predicts co-evolving protein residues and plots them on the 3D protein structure. Starting with a single protein sequence, InterMap3D automatically finds a set of homologous sequences, generates an alignment and fetches the most similar 3D structure from the Protein Data Bank (PDB). It can also accept a user-generated alignment. Based on the alignment, co-evolving residues are then predicted using three different methods: Row and Column Weighing of Mutual Information, Mutual Information/Entropy and Dependency. Finally, InterMap3D generates high-quality images of the protein with the predicted co-evolving residues highlighted.
  
  
  BACKGROUND
  http://www.cbs.dtu.dk/services/InterMap3D/.
authors.affiliation: Center for Biological Sequence Analysis, Technical University of Denmark, DK-2800 Lyngby, Denmark. gorm@cbs.dtu.dk
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Gouveia-Oliveira
authors.forename: Francisco S
authors.initials: FS
authors.lastname: Roque
authors.forename: Rasmus
authors.initials: R
authors.lastname: Wernersson
authors.forename: Thomas
authors.initials: T
authors.lastname: Sicheritz-Ponten
authors.forename: Peter W
authors.initials: PW
authors.lastname: Sackett
authors.forename: Anne
authors.initials: A
authors.lastname: Mølgaard
authors.forename: Anders G
authors.initials: AG
authors.lastname: Pedersen
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment / Q000379:methods; D020539:Sequence Analysis, Protein / Q000379:methods; D012984:Software
chemical_list: D011506:Proteins