Comparative assessment of Helicobacter pylori colonization in children tonsillar tissues.
OBJECTIVE
The objective was to survey the results of RUT (rapid urease test) in children tonsillar tissues.


METHODS
In a prospective clinical study 285 children (4-14 years) tonsillar tissue tested with RUT (rapid urease test) and histopathologic biopsy and simultaneously serum IgG Helicobacter pylori level was measured for all patients.


RESULTS
One hundred and thirteen patients (39.6%) were positive to H. pylori in histopathologic examination. Forty patients (14%) had positive RUT and 15 patients had positive serum IgG anti-H. pylori level. In 40 patients the results in both histopathology and RUT were positive (P=0.000) although in 172 patients the results in both histopatologhic and RUT were negative (P=0.000).


CONCLUSIONS
This study showed that H. pylori was present in tonsillar tissue and RUT is not sensitive enough for diagnosis of H. pylori in tonsillar tissue. Indicating that H. pylori has a possible role in reservoir of H. pylori in children.
Jabbari Moghaddam
Yalda
Y
Liver and Gastrointestinal Research Center, Tabriz University (Medical Sciences), Iran.
Rafeey
Mandana
M
Radfar
Reza
R
D000293:Adolescent; D001706:Biopsy; D001944:Breath Tests / Q000379:methods; D002648:Child; D002675:Child, Preschool; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G; D014066:Palatine Tonsil / Q000382:microbiology* / Q000473:pathology; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods; D014510:Urease / Q000378:metabolism
D007074:Immunoglobulin G; D014510:Urease