An unusual case of duodenal obstruction-gangliocytic paraganglioma.
Gangliocytic paragangliomas are rare tumors located in the gastrointestinal tract that are considered to be benign. They are composed of spindle-shaped cells, epithelioid cells, and ganglion-like cells. They usually present with abdominal pain, and/or gastrointestinal bleeding, and occasionally with obstructive jaundice. We report a case of obstruction in a 17-year-old female, which on histology was found to be a gangliocytic paraganglioma, with an extremely unusual presentation. Intraoperatively, the patient was found to have local tumor extension and regional lymph node invasion, and so she underwent a pylorus-preserving pancreaticoduodenectomy, with local lymph node clearance. We discuss the management of this unusual case and review the literature.
Mann
C M
CM
West Midlands Liver Unit, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham, B15 2TH, UK. carolinemmann@yahoo.co.uk
Bramhall
S R
SR
Buckels
J A
JA
Taniere
P
P
D000293:Adolescent; D004379:Duodenal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D008198:Lymph Nodes / Q000473:pathology; D009361:Neoplasm Invasiveness; D016577:Pancreaticoduodenectomy; D010235:Paraganglioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed