Pathogenesis of infectious disease of mice caused by H5N1 avian influenza virus.
The pathogenesis of a disease caused by Qinghai-like H5N1 influenza virus in BALB/c mice was studied. Clinical, morphological, and immunological characteristics of the experimental infection caused by highly pathogenic A/duck/Tuva/01/06/ (H5N1) virus are described.
Evseenko
V A
VA
Vector State Research Center of Virology and Biotechnology, Novosibirsk Region, Koltsovo, Russia. vasily.evseenko@gmail.com
Sharshov
K A
KA
Bukin
E K
EK
Zaykovskaya
A V
AV
Ternovoy
V A
VA
Ignatyev
G M
GM
Shestopalov
A M
AM
Netesov
S V
SV
Shkurupiy
V A
VA
Drozdov
I G
IG
D000818:Animals; D001483:Base Sequence; D006388:Hemagglutinins / Q000235:genetics; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*; D007371:Interferon-gamma / Q000378:metabolism; D016753:Interleukin-10 / Q000378:metabolism; D018664:Interleukin-12 / Q000378:metabolism; D053583:Interleukin-1beta / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D009439:Neuraminidase / Q000235:genetics; D009976:Orthomyxoviridae Infections / Q000473:pathology* / Q000821:virology*; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D014763:Viral Matrix Proteins / Q000737:chemistry; D014764:Viral Proteins / Q000235:genetics; D000086082:Viroporin Proteins
D006388:Hemagglutinins; D007371:Interferon-gamma; D016753:Interleukin-10; D018664:Interleukin-12; D053583:Interleukin-1beta; D015850:Interleukin-6; D009439:Neuraminidase; D012324:RNA-Dependent RNA Polymerase; D014409:Tumor Necrosis Factor-alpha; D014763:Viral Matrix Proteins; D014764:Viral Proteins; C488937:M2 protein, Influenza A virus; D000086082:Viroporin Proteins; C057027:PB2 protein, Influenzavirus A