Urinary 1-hydroxypyrene levels in offshore workers.
OBJECTIVE
To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group.


METHODS
Participants' (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models.


RESULTS
(1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels.


CONCLUSIONS
Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.
Hopf
Nancy Brenna
NB
University of Cincinnati, Cincinnati, OH, USA. NancyBHopf@gmail.com
Kirkeleit
Jorunn
J
Kramer
Stacy L
SL
Moen
Bente
B
Succop
Paul
P
Genter
Mary Beth
MB
Carreón
Tania
T
Mack
James
J
Talaska
Glenn
G
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D019652:Extraction and Processing Industry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*; D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis; D011721:Pyrenes / Q000032:analysis*
D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons; D011721:Pyrenes; C033146:1-hydroxypyrene