title: Case report: malignant teratoma of the uterine corpus.
abstract: BACKGROUND
  Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.
  
  
  METHODS
  We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.
  
  
  CONCLUSIONS
  In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.
authors.affiliation: Department of Medical Oncology, Imperial College School of Medicine, Charing Cross Hospital, London, UK. t.ndavis04@imperial.ac.uk
authors.forename: Thomas
authors.initials: T
authors.lastname: Newsom-Davis
authors.forename: Daniel
authors.initials: D
authors.lastname: Poulter
authors.forename: Rebecca
authors.initials: R
authors.lastname: Gray
authors.forename: Mohammed
authors.initials: M
authors.lastname: Ameen
authors.forename: Iain
authors.initials: I
authors.lastname: Lindsay
authors.forename: Kyriakos
authors.initials: K
authors.lastname: Papanikolaou
authors.forename: Simon
authors.initials: S
authors.lastname: Butler-Manuel
authors.forename: Timothy
authors.initials: T
authors.lastname: Christmas
authors.forename: Peter
authors.initials: P
authors.lastname: Townsend
authors.forename: Michael
authors.initials: M
authors.lastname: Seckl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008206:Lymphatic Diseases / Q000209:etiology; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000175:diagnosis*; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000175:diagnosis*
chemical_list: D005047:Etoposide; D002945:Cisplatin