title: Morphological changes in bird viscera in experimental infection by highly pathogenic H5N1 avian influenza virus.
abstract: Intravenous infection of chicken with H5N1 avian influenza virus (strain A/Gs/Krasnoozerskoye/627/05) causes rapid lethal outcome. Pathomorphological study of bird viscera showed manifestations of disseminated intravascular coagulation syndrome, generalized inflammatory reaction, and wide-scale necrobiotic changes in tissues.
authors.affiliation: Department of Physiology, Novosibirsk State University, Novosibirsk Region, Koltsovo, Russia. lv@fen.nsu.ru
authors.forename: L V
authors.initials: LV
authors.lastname: Shestopalova
authors.forename: V A
authors.initials: VA
authors.lastname: Shkurupiy
authors.forename: T V
authors.initials: TV
authors.lastname: Sharkova
authors.forename: A M
authors.initials: AM
authors.lastname: Shestopalov
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology / Q000821:virology; D002642:Chick Embryo; D002645:Chickens; D053124:Influenza A Virus, H5N1 Subtype / Q000472:pathogenicity*; D005585:Influenza in Birds / Q000473:pathology* / Q000821:virology*; D007668:Kidney / Q000473:pathology / Q000821:virology; D008168:Lung / Q000473:pathology / Q000821:virology; D013154:Spleen / Q000473:pathology / Q000821:virology; D014781:Viscera / Q000473:pathology* / Q000821:virology*