Significance of heart rate in the prevalence of metabolic syndrome and its related risk factors in Japanese.
BACKGROUND
Autonomic dysfunction is thought to be an important mechanism of metabolic syndrome (MetS), but there has not been a study on the direct association between MetS and heart rate (HR) in Japanese.


RESULTS
The association between MetS and HR was examined using medical check-up data from 1,880 men and 1,079 women. HR was significantly higher in MetS subjects than in non-MetS subjects in both men and women (P<0.0001 in men, P<0.001 in women). The prevalence of MetS increased linearly through the quartiles of HR in both men and women. HR was significantly correlated with MetS-related risk factors other than uric acid in men and other than uric acid, body mass index, waist circumference, and high-density lipoprotein cholesterol in women.


CONCLUSIONS
The prevalence of MetS increased linearly with the increase in HR among Japanese men and women, and HR was significantly correlated with MetS-related risk factors.
Oda
Eiji
E
Medical Check-up Center, Tachikawa Medical Center, Nagaoka, Japan. ijie@venus.sannet.ne.jp
Kawai
Ryu
R
D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000503:physiopathology*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D014527:Uric Acid / Q000097:blood; D055105:Waist Circumference
D008076:Cholesterol, HDL; D014527:Uric Acid