Peculiarities of compensatory reactions of hepatic vessels during experimental coarctation of aorta.
Morphometric and histological methods were employed to study structural changes of hepatic vessels in dogs with compensated coarctation. Simulation of this conditions in animals decreased vascular tone in the inflow and outflow beds of hepatic blood supply and led to the development of atrophy in the media. At the same time, the number of vessels with intimal musculature, elastic muscle sphincters, and polypoid cushions increased in the hepatic arterial bed, while large outflow veins demonstrated thinning of the muscle cushions. All these alterations play an important role in compensation of the disturbed hemodynamics.
Shormanov
S V
SV
Department of Pathological Anatomy, Yaroslavl State Medical Academy, Russia. kulik.doc@rambler.ru
Kulikov
S V
SV
D000818:Animals; D001017:Aortic Coarctation / Q000503:physiopathology*; D001808:Blood Vessels / Q000473:pathology / Q000503:physiopathology*; D004285:Dogs; D008099:Liver / Q000098:blood supply*