title: [Fixed combination perindopril-amlodipine (Coveram) in the treatment of hypertension and coronary heart disease].
abstract: Coveram is a new fixed combination of an angiotensin converting enzyme inhibitor, perindopril, and a calcium antagonist, amlodipine. This new medication is indicated for the treatment of arterial hypertension and/or stable coronary heart disease. Such fixed combination of two molecules that have been extensively evaluated according to evidence-based medicine offers the advantage of an excellent efficacy, associated with a good tolerance profile, and favours patient's compliance. The marketing of different formulations of Coveram combining various dosages allows easy adjustment and titration of each of the components according to the individual patient's characteristics.
authors.affiliation: Université de Liège.
authors.forename: A J
authors.initials: AJ
authors.lastname: Scheen
authors.forename: J M
authors.initials: JM
authors.lastname: Krzesinski
mesh_terms: D000284:Administration, Oral; D017311:Amlodipine / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D003327:Coronary Disease / Q000188:drug therapy; D004338:Drug Combinations; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D020913:Perindopril / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D004338:Drug Combinations; C542336:amlodipine, perindopril drug combination; D017311:Amlodipine; D020913:Perindopril