title: Speckle reduction in optical coherence tomography using angular compounding by B-scan Doppler-shift encoding.
abstract: We propose a novel method for speckle reduction for optical coherence tomography based on angular compounding by B-scan Doppler-shift encoding (AngularCBD). By decentering the probe beam from the pivot of a scanning mirror, the illumination angle represented by different components of the beam can be encoded in Doppler shift. Compounding multiple images reconstructed from different Doppler-shift bands, we can suppress speckle without sacrificing image acquisition speed. Speckle reduction with AngularCBD is demonstrated by imaging a phantom and tissue sample in vitro and in vivo.
authors: Hui
authors: H
authors: Wang
authors: Andrew M
authors: AM
authors: Rollins
mesh_terms: D000818:Animals; D004625:Embryo, Nonmammalian / Q000033:anatomy & histology; D004947:Esophagus / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D007089:Image Enhancement / Q000379:methods*; D019047:Phantoms, Imaging; D011784:Quail; D013552:Swine; D041623:Tomography, Optical Coherence / Q000379:methods*; D018608:Ultrasonography, Doppler / Q000379:methods*