Polypharmacy in the elderly: focus on drug interactions and adherence in hypertension.
Polypharmacy is highly prevalent in the elderly due to an increased number of co-morbid disease states that accompany aging. Hypertension is one common disease that can be challenging to treat in the elderly due to the body's physiologic changes, potential risks for side effects, medication interactions, and decreased medication adherence. A thorough medication assessment for each patient is essential when determining pharmacotherapeutic options in the elderly.
Cooney
Danielle
D
Department of Pharmacy, Louis Stokes Veterans Affairs Medical Center, Pharmacy Service (119W), 10701 East Blvd, Cleveland, OH 44106, USA. danielle.corwin@va.gov
Pascuzzi
Kristina
K
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000378:metabolism; D004347:Drug Interactions / Q000502:physiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D019338:Polypharmacy; D015995:Prevalence; D012307:Risk Factors
D000959:Antihypertensive Agents