[Preparation of compound PuHuang granules and its clinical efficacy].
OBJECTIVE
To prepare Compound PuHuang Granules and observe its clinical efficacy on cerebral infarction.


METHODS
The Compound PuHuang Granules were prepared and the identification was performed by TLC. A total of 328 patients with cerebral infarction were randomly divided into two groups and observed. 197 cases in the trial group were administered with Compound PuHuang Granules for 2 weeks, and 131 cases in the control group were administered with NaoXueShuan Tablets for 2 weeks as well.


RESULTS
The method of identification was proved to be specific and reproductive. The effective rates of the trial group and the control group on vertigo, hemiplegia, numbness of extremities were 88.71%, 82.46%, 84.38% and 61.11%, 62.07%, 66.67%, respectively, which showed significances between the two groups (P < 0.05). But the effective rates of two groups on language disorder showed no signifcance.


CONCLUSIONS
The Compound PuHuang Granules is feasible in preparation and it has obvious efficacy, therefore, it would be useful in the clinical applications.
Xu
Hong-Bin
HB
Department of Pharmacy, Tenth People's Hospital, Tongji University, Shanghai 200072, China. jiangruihua119@sohu.com
Zhang
Li-Ming
LM
Li
Ling
L
D000284:Administration, Oral; D000328:Adult; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002544:Cerebral Infarction / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005343:Fibrinolytic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007865:Leeches / Q000737:chemistry; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D013678:Technology, Pharmaceutical / Q000379:methods*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005343:Fibrinolytic Agents; D008055:Lipids