title: Higher hospital volume is associated with lower mortality in acute nonvariceal upper-GI hemorrhage.
abstract: BACKGROUND
  Acute nonvariceal upper-GI hemorrhage (NVUGIH) is associated with significant morbidity and mortality.
  
  
  OBJECTIVE
  To examine the relationship between hospital volume and outcomes of NVUGIH.
  
  
  METHODS
  A cross-sectional study.
  
  
  METHODS
  Participating hospitals from the Nationwide Inpatient Sample 2004.
  
  
  METHODS
  All discharged patients with a primary discharge diagnosis of NVUGIH based on the International Classification of Diseases, Clinical Modification, ninth edition codes.
  
  
  METHODS
  Patients were divided into 3 groups based on discharge from hospitals with annual discharge volumes of 1 to 125 (low), 126 to 250 (medium), and >250 (high).
  
  
  METHODS
  In-hospital mortality, length of stay, and hospitalization charges.
  
  
  RESULTS
  The study included a total of 135,366, 132,746, and 123,007 discharges with NVUGIH occurred from low-volume, medium-volume, and high-volume hospitals, respectively. On multivariate analysis, when adjusting for age, comorbidity, and the presence of complications, patients at high-volume hospitals had significantly lower in-hospital mortality (odds ratio [OR] 0.85 [95% CI, 0.74-0.98]) than patients at low-volume hospitals. Patients at high-volume hospitals were also more likely to undergo upper-GI endoscopy (OR 1.52 [95% CI, 1.36-1.69]) or early endoscopy within 1 day of hospitalization compared with low-volume hospitals (60.5% vs 53.8%, adjusted OR 1.28 [95% CI, 1.02-1.61]). Undergoing endoscopy within day 1 was associated with shorter hospital stays (-1.08 days [95% CI, -1.24 to -0.92 days]) and lower hospitalization charges (-$1958 [95% CI, -$3227 to -$688]).
  
  
  CONCLUSIONS
  The study was based on an administrative data set.
  
  
  CONCLUSIONS
  Higher hospital volume is associated with lower mortality and with higher rates of endoscopy and endoscopic intervention in patients with NVUGIH.
authors: Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. aanantha@mcw.edu
authors: Ashwin N
authors: AN
authors: Ananthakrishnan
authors: Emily L
authors: EL
authors: McGinley
authors: Kia
authors: K
authors: Saeian
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D002983:Clinical Competence; D016001:Confidence Intervals; D004638:Emergency Treatment; D004932:Esophageal and Gastric Varices; D004945:Esophagoscopy / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy*; D016558:Hemostasis, Endoscopic / Q000706:statistics & numerical data; D017721:Hospital Costs; D017052:Hospital Mortality; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D017063:Outcome Assessment, Health Care; D010351:Patient Discharge / Q000191:economics / Q000706:statistics & numerical data; D011336:Probability; D018570:Risk Assessment; D016019:Survival Analysis; D016526:Workload / Q000191:economics / Q000706:statistics & numerical data*