[Collonization of intestinal tract of leukaemia patients with Candida and development of systemic candidemia].
The aim of the research was to study the peculiarities of colonization of intestinal tract by Candida - in children with leukemia. It was found that in 32 out of 54 patients with leukaemia the quantity of intestinal KOE Candida in 1 g feces was correlated with the incidence of candidemia. The quantity of intestinal KOE/g Candida was higher in patients receiving antileukemic chemotherapy and antibacterial antibiotics than in normal subjects in patients with The quantity of Candida KOE/g feces was >10(5) cells per 1g of substrate. In control group this figure was within 10(3)-10(4). In all patients candidemia was revealed. In 8 patients who were not treated with antibiotics the quantity of Candida in feces was present to a less degree (<0.05). In the majority of cases (70%) in patients with leukaemia C.albicans was found, in 15% of cases - C. tropicalis. Along side with candidemia candidiazes of respiratory and urinary systems was revealed in children with leukaemia.
Dzhavadov
S S
SS
Suleĭmanova
T Kh
TKh
D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002175:Candida / Q000302:isolation & purification; D002177:Candidiasis / Q000175:diagnosis / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D016469:Fungemia / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007108:Immune Tolerance; D007422:Intestines / Q000382:microbiology*; D007938:Leukemia / Q000150:complications* / Q000188:drug therapy / Q000276:immunology
D000970:Antineoplastic Agents