Polycyclic N-heterocyclic compounds. part 59: rearrangement reactions of fused tricyclic 3-(2-bromoethyl)pyrimidin-4(3h)-ones with primary amines via a dimroth-type rearrangement.
Reaction of some fused tricyclic 3-(2-bromoethyl)pyrimidin-4(3H)-ones with primary alkyl amines gave abnormal fused 3-alkyl-4-alkyliminopyrimidines via a Dimroth-type rearrangement, as well as normal substituted 3-(2-alkylaminoethyl) derivatives in methanol. This abnormal rearrangement reaction depended on reaction solvent.
Okuda
Kensuke
K
Gifu Pharmaceutical University.
Ohtomo
Hiromi
H
Tanaka
Fumiaki
F
Hirota
Takashi
T
Sasaki
Kenji
K
D000588:Amines / Q000737:chemistry*; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000737:chemistry*; D011744:Pyrimidinones / Q000737:chemistry*
D000588:Amines; D011083:Polycyclic Compounds; D011744:Pyrimidinones