A novel lab-on-a-tube for multimodality neuromonitoring of patients with traumatic brain injury (TBI).
A novel lab-on-a-tube integrated with spirally-rolled pressure, temperature, oxygen and glucose microsensors is described for multimodal neuromonitoring of patients with traumatic brain injury. In addition to measuring various crucial parameters in real-time continuous formats, the newly developed device also works as an intraventricular catheter to lower the elevated intracranial pressure by draining cerebrospinal fluid.
Li
Chunyan
C
Department of Neurosurgery, University of Cincinnati (UC) Neuroscience Institute, Cincinnati, Ohio 45267, USA. lic2@email.uc.edu
Wu
Pei-Ming
PM
Jung
WooSeok
W
Ahn
Chong H
CH
Shutter
Lori A
LA
Narayan
Raj K
RK
D015374:Biosensing Techniques; D001930:Brain Injuries / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D056656:Lab-On-A-Chip Devices; D046208:Microchip Analytical Procedures / Q000379:methods*; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D012680:Sensitivity and Specificity; D013997:Time Factors