title: Treatment responses in antiretroviral treatment-naive premenopausal and postmenopausal HIV-1-infected women: an analysis from AIDS Clinical Trials Group Studies.
abstract: Menopause may affect antiretroviral treatment (ART) response. Immunologic and virologic responses to ART were compared in 220 premenopausal and 47 postmenopausal women enrolled in 2 studies involving ART-naive persons. Changes in CD4 counts or human immunodeficiency virus type 1 RNA levels were similar at 24, 48, and 96 weeks after treatment initiation. ART-naive women should respond to ART regardless of menopausal status.
authors: University of North Carolina, Chapel Hill, NC 27599-7215, USA. kristine_patterson@med.unc.edu
authors: Kristine B
authors: KB
authors: Patterson
authors: Susan E
authors: SE
authors: Cohn
authors: Jennifer
authors: J
authors: Uyanik
authors: Michael
authors: M
authors: Hughes
authors: Marlene
authors: M
authors: Smurzynski
authors: Joseph J
authors: JJ
authors: Eron
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D018791:CD4 Lymphocyte Count; D005260:Female; D015497:HIV-1 / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D017697:Premenopause; D016896:Treatment Outcome; D014481:United States; D019562:Viral Load