title: Phenolic constituents from Balanophora laxiflora with DPPH radical-scavenging activity.
abstract: Balanophora laxiflora HEMSL. (Balanophoraceae), a dioeciously parasitic plant, has been used as a tonic and for sobering up from drunk by the local people of Yunnan province, China. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay on the acetone extract of the fresh female plant of B. laxiflora displayed considerable radical-scavenging activity (SC(50)=16.4 microg/ml). Further purification of the extract led to the isolation of two new phenolic glycosides, balaxiflorins A and B (1 and 2, resp.), together with 17 known phenolic compounds including 3-phenylpropanoids, 3, 17-18, four lignans, 4-7, nine hydrolyzable tannins, 8-16, and gallic acid (19). Their structures were determined by detailed spectroscopic analysis. The free-radical-scavenging activity of the isolated compounds was examined by DPPH assay.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, P. R. China.
authors: Gai-Mei
authors: GM
authors: She
authors: Ying-Jun
authors: YJ
authors: Zhang
authors: Chong-Ren
authors: CR
authors: Yang
mesh_terms: D031111:Balanophoraceae / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000378:metabolism*; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates / Q000378:metabolism*; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006027:Glycosides; D010636:Phenols; D010851:Picrates; D010936:Plant Extracts; C543339:balaxiflorin A; C543340:balaxiflorin B; C004931:1,1-diphenyl-2-picrylhydrazyl