title: Short sleep duration is associated with a blood pressure nondipping pattern in type 1 diabetes: the DIAPASOM study.
abstract: OBJECTIVE
  To assess whether nocturnal blood pressure dipping status in type 1 diabetes is correlated with specific sleep characteristics and differences in nocturnal glycemic profiles.
  
  
  METHODS
  Twenty type 1 diabetic adult patients underwent sleep studies with simultaneous 24-h ambulatory blood pressure monitoring and continuous nocturnal glucose monitoring.
  
  
  RESULTS
  Altogether, 55% of patients exhibited blunted blood pressure dipping. They did not differ from the dipper group in age, BMI, or systolic (SBP) and diastolic (DBP) blood pressure. Total sleep period (TSP) was higher in the dipper group (497 +/- 30 vs. 407 +/- 44 min for dippers and nondippers, respectively, P < 0.001). TSP was correlated with SBP and DBP day-night differences (r = 0.44 and 0.49, respectively). Periods of nocturnal hypoglycemia (i.e., % of TSP with glycemia <70 mg/dl) were longer in the dipper group (8.1 +/- 10.7 vs. 0.1 +/- 0.4% for dippers and nondippers, respectively, P = 0.02).
  
  
  CONCLUSIONS
  Dipping status in type 1 diabetes was associated with longer sleep duration and with hypoglycemia unawareness.
authors: Endocrinology Department, University Hospital, Pôle Digidune, Joseph Fourier University, Grenoble, France. alborel@chu-grenoble.fr
authors: Anne-Laure
authors: AL
authors: Borel
authors: Pierre-Yves
authors: PY
authors: Benhamou
authors: Jean-Philippe
authors: JP
authors: Baguet
authors: Isabelle
authors: I
authors: Debaty
authors: Patrick
authors: P
authors: Levy
authors: Jean-Louis
authors: JL
authors: Pépin
authors: Jean-Michel
authors: JM
authors: Mallion
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012890:Sleep / Q000502:physiology*