title: [The results of transbronchial needle aspiration in 164 cases with enlarged mediastinal and/or hilar lymph nodes].
abstract: OBJECTIVE
  To evaluate the role of transbronchial needle aspiration (TBNA) in the diagnosis of patients with enlarged mediastinal and/or hilar lymph node.
  
  
  METHODS
  Patients with mediastinal and/or hilar lymphoadenopathy proven by CT scan were eligible for TBNA as reported. All specimens were directly and instantly smeared for pathological examination.
  
  
  RESULTS
  From June 1 2004 to December 31 2007, 164 patients were examined: including 80 lung cancers, 69 lung benign diseases, 2 other malignancy tumor, and 13 without definite diagnosis. Total 260 lymph nodes were punctured. TBNA procedures were successfully carried out in 445/463 (96.1%). Sensitivity of TBNA was 82.5% (66/80) in patients who had been proven to suffer from bronchogenic carcinoma. There were 25 patients that diagnosis of lung cancer was pathologically determined by TBNA only. A total of 122 lymph nodes in the 80 lung cancer patients were aspirated by TBNA with a positive rate of 65.6% (80/122). Severe complications were rare except small amount of bleeding at the TBNA site (100/164, 61.0%). From June 1 2006 to December 31 2007, lymph node tissues able to make histology diagnosis were yield in 73.5% (64/87) patients. Through histology pathology, the sensitivities of TBNA were 53.3% (8/15) for sarcoidosis and 78.6% (33/42) for lung cancer.
  
  
  CONCLUSIONS
  TBNA is quite safe and helpful in diagnosis and staging of bronchogenic carcinoma, and in diagnosis of benign lung diseases.
authors: Department of Respiratory Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. mengzhaowang@sina.com
authors: Meng-Zhao
authors: MZ
authors: Wang
authors: Xiao-Bing
authors: XB
authors: Wan
authors: Yong
authors: Y
authors: Chen
authors: Li
authors: L
authors: Zhang
authors: Wei
authors: W
authors: Zhong
authors: Xu
authors: X
authors: Zhong
authors: Ju-Hong
authors: JH
authors: Shi
authors: Tao
authors: T
authors: Liu
authors: Hui
authors: H
authors: Huang
authors: Hong
authors: H
authors: Zhang
authors: Yi
authors: Y
authors: Xiao
authors: Bai-Qiang
authors: BQ
authors: Cai
authors: Long-Yun
authors: LY
authors: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008482:Mediastinum / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D055815:Young Adult