A new C-C bond forming annulation reaction leading to pH switchable heterocycles.
A C-C bond forming reaction resulting from the alpha-addition of carbon based nucleophiles to N-bromoethyl phenanthridinium leads to the formation of 2,3-dihydro-12H-pyrrolo[1,2-f]phenanthridine-based derivatives which undergo reversible ring-opening/closing under pH control.
Kitson
Philip J
PJ
WestCHEM, Department of Chemistry, The University of Glasgow, Glasgow, UK G12 8QQ.
Parenty
Alexis D C
AD
Richmond
Craig J
CJ
Long
De-Liang
DL
Cronin
Leroy
L