Wet-spinning of osmotically stressed silk fibroin.
Based on the phase diagram constructed for water-silk fibroin-LiBr using the osmotic stress method, wet-spinning of osmotically stressed, regenerated Bombyx mori silk fibroin was performed, without the necessity of using expensive or toxic organic solvents. The osmotic stress was applied to prestructure the regenerated silk fibroin molecule from its original random coil state to a more oriented state, manipulating the phase of the silk solution in the phase diagram before the start of spinning. Various starting points for spinning were selected from the phase diagram to evaluate the spinning performance and also physical properties of fibers produced. Monofilament fiber with a diameter of 20 microm was produced. It was found that the fibers whose starting point in the phase diagram were around the phase boundary between silk I and silk II, at very low LiBr concentrations, showed the best spinning process stability and physical properties. This underpins the prediction that the enhanced control over structure and phase behavior using the osmotic stress method helps improve the physical properties of wet-spun regenerated silk fibroin fibers.
Sohn
Sungkyun
S
Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA. sksohn@mail.pse.umass.edu
Gido
Samuel P
SP
D000818:Animals; D012831:Bombyx; D005349:Fibroins / Q000737:chemistry*; D009997:Osmotic Pressure; D047011:Silk / Q000032:analysis / Q000138:chemical synthesis*; D012965:Sodium Chloride; D013059:Spectrum Analysis, Raman; D014867:Water / Q000737:chemistry*; D014961:X-Ray Diffraction
D047011:Silk; D014867:Water; D012965:Sodium Chloride; D005349:Fibroins