Treatise on the measurement of molecular masses with ion mobility spectrometry.
The ability to separate isotopes by high-resolution ion mobility spectrometry techniques is considered as a direct means for determining mass at ambient pressures. Calculations of peak shapes from the transport equation show that it should be possible to separate isotopes for low-mass ions (<200) by utilizing heavy collision gases and high-resolution ion mobility analyzers. The mass accuracy associated with this isotopic separation approach based on ion mobility separation is considered. Finally, we predict several isotopes that should be separable.
Valentine
Stephen J
SJ
Department of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47405, USA. stvalent@indiana.edu
Clemmer
David E
DE
D007477:Ions / Q000737:chemistry / Q000302:isolation & purification; D007536:Isomerism; D007554:Isotopes / Q000737:chemistry / Q000302:isolation & purification; D008956:Models, Chemical; D008970:Molecular Weight; D009038:Motion; D011312:Pressure; D013057:Spectrum Analysis / Q000379:methods*; D013696:Temperature
D007477:Ions; D007554:Isotopes