Bacteriology of spontaneously draining acute otitis media in children before and after the introduction of pneumococcal vaccination.
Bacterial growth from spontaneously draining middle ear fluid was compared for periods before (1993-1998) and after (2001-2006) introduction of routine pneumococcal vaccination Staphylococcus aureus, including MRSA, was more common (P < .05) in the latter period.
Brook
Itzhak
I
Department of Pediatrics Georgetown, University School of Medicine, Washington, DC, USA. ib6@georgetown.edu
Gober
Alan E
AE
D002648:Child; D002675:Child, Preschool; D004432:Ear, Middle / Q000382:microbiology*; D005122:Exudates and Transudates / Q000382:microbiology*; D005260:Female; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D008297:Male; D010033:Otitis Media / Q000453:epidemiology / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D022242:Pneumococcal Vaccines / Q000276:immunology*; D015995:Prevalence; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000302:isolation & purification
D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022242:Pneumococcal Vaccines