Chemotherapy-associated renal dysfunction.
The presence of renal dysfunction in a patient receiving chemotherapy can be devastating. Although many patients with cancer have underlying compromised renal function, some chemotherapeutic agents can actually induce renal abnormalities. An understanding of which traditional and newer chemotherapy agents can affect renal function is useful for physicians so that they can monitor patients for renal abnormalities and initiate preventive strategies to minimize renal complications. This Review highlights renal abnormalities associated with current chemotherapy agents and provides suggestions for preventive measures.
Sahni
Vaibhav
V
Drexel University College of Medicine, Philadelphia, PA 19102-1192, USA.
Choudhury
Devasmita
D
Ahmed
Ziauddin
Z
D000970:Antineoplastic Agents / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D051437:Renal Insufficiency / Q000139:chemically induced*; D012307:Risk Factors
D000970:Antineoplastic Agents