[Measurement of exhaled nitric oxide in healthy Chinese].
OBJECTIVE
To obtain the normal values of nitric oxide (NO) exhaled through nose and mouth in healthy Chinese adults by measuring exhaled NO and analyzing the influencing factors.


METHODS
Eighty healthy Chinese adults were recruited, including 20 males and 60 females. The age ranged from 18 to 44 years old. Chemiluminescence analyzer (NIOX) was used to obtain the values of exhaled NO through nose and mouth. The relativity between NO and gender, age, height, body mass index, time, ambient NO were analyzed with Multiple linear regression and correlation.


RESULTS
Exhaled NO values were (17+/-8)x10(-9) and correlated significantly with height. Regression equation: Y (exhaled nitric oxide)=-58.524+0.457X (height, cm), t=-2.985, P<0.01. Transnasal NO values were (819+/-211)x10(-9) and correlated significantly with age and gender. Regression equation: Y (nasal nitric oxide)=760.245+9.417X1(age)-111.222X2(gender), t=5.188, P<0.01.


CONCLUSIONS
Exhaled NO normal values were 17x10(-9) and Transnasal NO normal values were 819x10(-9). Exhaled NO correlated positively with height. Transnasal NO correlated positively with age and negatively with gender.
Zhang
Luo
L
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Allergic Rhinitis Clinics, Beijing Institute of Otorhinolaryngology, Beijing 100730, China. luozhang@trhos.com
Luo
Xue-rui
XR
Liu
Cheng-yao
CY
Zhao
Yan
Y
Han
De-min
DM
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D044466:Asian People; D001827:Body Height; D015992:Body Mass Index; D001944:Breath Tests; D045853:Exhalation / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009055:Mouth / Q000502:physiology; D009569:Nitric Oxide / Q000032:analysis*; D009666:Nose / Q000502:physiology; D012016:Reference Values; D012737:Sex Factors; D055815:Young Adult
D009569:Nitric Oxide