title: Reversible metronidazole-induced cerebellar toxicity in a multiple transplant recipient.
abstract: Metronidazole-induced central nervous system (CNS) toxicity causes a spectrum of neurological symptoms including ataxia, encephalopathy and peripheral neuropathy. It is associated with characteristic MRI changes of high signal intensity in the dentate nuclei. Given the increasing use of metronidazole, it is import to recognise this drug as a cause of ataxia, as it is entirely reversible on drug withdrawal.
authors: Department of Neurology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0NS, United Kingdom.
authors: Tracey D
authors: TD
authors: Graves
authors: Marie
authors: M
authors: Condon
authors: Marina
authors: M
authors: Loucaidou
authors: Richard J
authors: RJ
authors: Perry
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D001259:Ataxia / Q000139:chemically induced* / Q000473:pathology; D001921:Brain / Q000187:drug effects / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D008795:Metronidazole / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D008875:Middle Aged; D016035:Pancreas Transplantation
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole