Plasmodium falciparum and Plasmodium vivax: so similar, yet very different.
The recently published whole genome sequence information of one of the human malaria parasites, Plasmodium vivax, have provided opportunities to compare similar features with Plasmodium falciparum that causes the most deadly form of human malaria. We herewith present comparative genomic insights into the whole genome of the two parasites and also to several other characteristics in terms of disease pathogenecity, evolution, etc. We show that while high similarities exist at the functional gene level, several contrasting features for other characteristics are hallmarks of these two human malaria parasites.
Das
Aparup
A
Evolutionary Genomics and Bioinformatics Laboratory, National Institute of Malaria Research, Sector 8, Dwarka, New Delhi 110 077, India. aparup@mrcindia.org
Sharma
Meenu
M
Gupta
Bhavna
B
Dash
Aditya Prasad
AP
D000818:Animals; D017125:Genes, Protozoan; D018503:Genome, Protozoan; D006801:Humans; D008288:Malaria / Q000469:parasitology; D010963:Plasmodium falciparum / Q000235:genetics* / Q000472:pathogenicity; D010966:Plasmodium vivax / Q000235:genetics* / Q000472:pathogenicity; D037521:Virulence Factors / Q000235:genetics*
D037521:Virulence Factors