Sleuthing the source of regeneration by MSCs.
Mesenchymal stem cells (MSCs) can differentiate into useful cell types and also have the ability to modulate inflammation. In this issue of Cell Stem Cell, Lee et al. (2009) investigate the production of the soluble inflammation inhibitor TSG-6 by MSCs.
Pittenger
Mark
M
Pearl LifeScience Partners, LLC, Baltimore, MD 21227, USA. mfpittenger@comcast.net
D000818:Animals; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D006321:Heart / Q000502:physiology; D006335:Heart Injuries / Q000628:therapy; D006801:Humans; D008168:Lung / Q000378:metabolism; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000502:physiology; D051379:Mice; D012333:RNA, Messenger / Q000378:metabolism; D012038:Regeneration
D015815:Cell Adhesion Molecules; D012333:RNA, Messenger; C072273:TNFAIP6 protein, human