title: Iliac cortical thickness in the neonate - the gradient effect.
abstract: Recent studies of the neonatal ilium are beginning to reveal that a recognizable structural patterning of trabecular bone is present in the absence of any direct stance-related weight transfer. However, little is known about the organization of compact bone in the ilium and the way in which it is laid down during the earliest stages of development. This study investigates cortical bone thickness across both gluteal and pelvic iliac shells in the human neonatal ilium. Measurements of specific regions of interest on the iliac cortices were recorded using reconstructed micro-computed tomography scans from 30 neonatal ilia. Analysis of gluteal and pelvic cortical thicknesses revealed a distinctive patterning consistent with the expected bone distribution achieved through early bone modelling and remodelling. The analysis of this pattern is important for understanding the relationship between trabecular bone patterning and cortical bone structure in the earliest stages of pelvic development prior to locomotive influences and its response to the specific functional forces acting during this period.
authors: Centre for Anatomy and Human Identification, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK. c.a.cunningham@dundee.ac.uk
authors: Craig A
authors: CA
authors: Cunningham
authors: Sue M
authors: SM
authors: Black
mesh_terms: D016723:Bone Remodeling / Q000502:physiology; D006801:Humans; D007085:Ilium / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000502:physiology; D007231:Infant, Newborn / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology; D055114:X-Ray Microtomography / Q000379:methods