title: Psychosocial aspects of genetic testing.
abstract: OBJECTIVE
  With rapid advances in genetic testing for disease susceptibility, behavioral medicine faces significant challenges in identifying likely patterns of use, how individuals interpret test results, and psychosocial and health impacts of testing. We review recent research on these psychosocial aspects of genetic testing for disease risk.
  
  
  RESULTS
  Individuals exhibit limited sensitivity in their perceptions of genetic risk information, and mental representations of disease risk appear to guide testing perceptions and behavioral responses. Motivations to undergo testing are complex, and efforts to develop decision aids are underway. Findings on psychological and behavioral impacts of genetic testing vary markedly, with some evidence of minimal or positive effects and other evidence indicating negative consequences that may be undetectable using common measures of general well being. Recent evidence suggests that genetic risk information can motivate health behavior change. Research demonstrates wide-ranging influences of testing on family dynamics, and use of genetic testing with children is of increasing concern.
  
  
  CONCLUSIONS
  More research is needed to determine how to structure health communications and counseling to motivate informed use, promote positive responses, and optimize behavior change. Given the ramifications of genetic information for families, personalized genomics will demand a shift toward a family-based healthcare model.
authors: Department of Psychology (Tamaki Campus), The University of Auckland, Auckland, New Zealand. L.cameron@auckland.ac.nz
authors: Linda D
authors: LD
authors: Cameron
authors: Cecile
authors: C
authors: Muller
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D001521:Behavior Therapy; D002648:Child; D003142:Communication; D003469:Culture; D003657:Decision Making; D054541:Family Conflict / Q000523:psychology; D005817:Genetic Counseling / Q000523:psychology; D030342:Genetic Diseases, Inborn / Q000235:genetics* / Q000523:psychology*; D005820:Genetic Testing / Q000523:psychology*; D023281:Genomics; D015438:Health Behavior; D006801:Humans; D055809:Illness Behavior; D011788:Quality of Life / Q000523:psychology*; D018570:Risk Assessment; D055815:Young Adult