Multidisciplinary management of primary tumors of the vertebral column.
Primary spinal neoplasms are rare tumors that can lead to significant morbidity secondary to local bone destruction and invasion into adjacent neurological and vascular structures. These tumors represent a clinical challenge to even the most experienced physicians and require a multidisciplinary approach to ensure optimal patient outcomes. This review will discuss the most common primary bone tumors and focus on recent surgical, medical, and radiation treatment advances.
Hsu
Wesley
W
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. weshsu@jhmi.edu
Kosztowski
Thomas A
TA
Zaidi
Hasan A
HA
Dorsi
Michael
M
Gokaslan
Ziya L
ZL
Wolinsky
Jean-Paul
JP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017824:Bone Cysts, Aneurysmal / Q000628:therapy; D002648:Child; D002817:Chordoma / Q000601:surgery; D003131:Combined Modality Therapy; D019468:Disease Management; D004621:Embolization, Therapeutic; D005870:Giant Cell Tumors / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy; D006391:Hemangioma / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D033183:Interdisciplinary Communication; D008875:Middle Aged; D018213:Neoplasms, Bone Tissue / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D054219:Neoplasms, Plasma Cell / Q000188:drug therapy / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D055815:Young Adult