Congenital toxoplasmosis after a preconceptional or periconceptional maternal infection.
We report a case of asymptomatic congenital toxoplasmosis following a periconceptional infection of the mother. Fetal infection is very uncommon in such a situation, and mostly associated with fetal damage. We recommend that newborns undergo postnatal screening, even after maternal periconceptional infection, and receive specific therapy to reduce long-term sequelae.
Robert-Gangneux
Florence
F
Laboratoire de Parasitologie-Mycologie, Centre Hospitalier et Universitaire et Faculté de Médecine, Université Rennes 1, Rennes, France. florence.robert-gangneux@univ-rennes1.fr
Yera
Hélène
H
D'Herve
Dominique
D
Guiguen
Claude
C
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D016054:DNA, Protozoan / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D010920:Placenta / Q000469:parasitology; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis* / Q000188:drug therapy; D015572:Spiramycin / Q000627:therapeutic use; D014122:Toxoplasma / Q000302:isolation & purification; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000635:transmission*; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
D000913:Antibodies, Protozoan; D000981:Antiprotozoal Agents; D016054:DNA, Protozoan; D007074:Immunoglobulin G; D015572:Spiramycin