Urinary biomarkers: the future looks promising.
Soler-García and collaborators show that changing levels of urinary biomarkers associated with the pathology of HIV-associated nephropathy may identify HIV-infected children at greatest risk for this complication. These changes appear relatively early in disease progression and remain responsive to antiviral therapy. Will these trends be borne out in a multicenter study?
Kiley
Susan C
SC
Department of Pediatrics, University of Virginia, Charlottesville, Virginia 22908, USA. sck3k@virginia.edu
Chevalier
Robert L
RL
D016263:AIDS-Associated Nephropathy / Q000175:diagnosis*; D015415:Biomarkers / Q000652:urine*; D004815:Epidermal Growth Factor / Q000652:urine; D016222:Fibroblast Growth Factor 2 / Q000652:urine; D006801:Humans; D020778:Matrix Metalloproteinase 2 / Q000652:urine
D015415:Biomarkers; D016222:Fibroblast Growth Factor 2; D004815:Epidermal Growth Factor; D020778:Matrix Metalloproteinase 2