Amiodarone induced liver cirrhosis. Report of two cases.
Amiodarone is used commonly in patients with cardiac diseases. Common side effects include thyroid dysfunction and hepatic abnormalities. However, recently there has been concern for developing liver cirrhosis secondary to amiodarone therapy. We present two cases of liver cirrhosis in patients taking amiodarone. Their clinical presentation as well as histological features are discussed in detail.
Atiq
Muslim
M
Division of Gastroenterology and General Medicine, Department of Internal Medicine, University of Arkansas for Medical Sciences, USA.
Davis
Jeremy C
JC
Lamps
Laura W
LW
Beland
Susan S
SS
Rose
James E
JE
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008103:Liver Cirrhosis / Q000139:chemically induced* / Q000473:pathology; D008297:Male
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone