Determination of carbamazepine in aquatic organisms by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry.
A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the determination of carbamazepine in microgram quantities of crustacean Thamnocephalus platyurus and the algae Pseudokirchneriella subcapitata at the ng L(-1) level. This fully validated method applied to a bioaccumulation study was found suitable for the detection of carbamazepine in small aquatic tissues.
Lajeunesse
André
A
Environment Canada, Fluvial Ecosystem Research, Science and Technology Branch, 105 McGill St., Montreal, Quebec, Canada H2Y 2E7. andre.lajeunesse@ec.gc.ca
Vernouillet
Gabrielle
G
Eullaffroy
Philippe
P
Gagnon
Christian
C
Juneau
Philippe
P
Sauvé
Sébastien
S
D000818:Animals; D033202:Anostraca / Q000737:chemistry*; D002220:Carbamazepine / Q000032:analysis*; D002853:Chromatography, Liquid; D004784:Environmental Monitoring / Q000379:methods*; D056890:Eukaryota / Q000737:chemistry*; D053719:Tandem Mass Spectrometry; D014874:Water Pollutants, Chemical / Q000032:analysis*
D014874:Water Pollutants, Chemical; D002220:Carbamazepine