[Clinical observation on transcutaneous electrical acupoint stimulation for treatment of functional dyspepsia].
OBJECTIVE
To compare the therapeutic effects of transcutaneous electrical point stimulation and medication on functional dyspepsia.


METHODS
Two hundred and fifty cases were randomly divided into an observation group and a control group, 125 cases in each group. The observation group was treated with transcutaneous electrical acupoint stimulation and oral administration of placebo, transcutaneous electrical stimulated at Zusanli (ST 36), Liangmen (ST 21), Taichong (LR 3) etc. The control group was treated with oral administration of Mosapride citrate dispersible tablets, Domperidone and Omeprazole and the placebo treatment of transcutaneous electrical acupoint stimulation, the stimulated position was 3-4 cm to the selected points of the observation group, the amount of the stimulation did not reach the treatment amount. The symptom score, the plasma motilin (MTL) concentration and the somatostatin (SS) concentration were observed before and after treatment of 3 courses.


RESULTS
All symptom scores after treatment were lower than that before treatment in the two groups, the scores of the upper abdominal pain, acid regurgitation, belching and abdominal distention in the observation group were significantly lower than that in the control group (P < 0.05, P < 0.01); the treatments of both two groups can increase the plasma MTL concentration and decrease the SS concentration (both P < 0.001), and the plasma MTL concentration in the observation group was significantly higher than that in the control group (P < 0.01), and the SS concentration was significantly lower than that in the control group (P < 0.05).


CONCLUSIONS
Transcutaneous electrical point stimulation can more reduce the symptoms of upper abdominal pain, acid regurgitation, belching and abdominal distention, etc. in the functional dyspepsia patients than medication treatment, and can increase the concentration of the plasma MTL and decrease the SS concentration, thus to improve the gastrointestinal motility.
Zhou
Guo-ying
GY
Department of Rehabilitation Medicine, The First Affiliated Hospital of Xinxiang Medical College, Weihui 453100, China. zhouxiaoguo@yahoo.com.cn
Zhou
Guo-sheng
GS
Jian-hong
Jin
J
D015669:Acupuncture Points; D000328:Adult; D000368:Aged; D001549:Benzamides / Q000008:administration & dosage / Q000627:therapeutic use; D004294:Domperidone / Q000008:administration & dosage / Q000627:therapeutic use; D004415:Dyspepsia / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005765:Gastrointestinal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009025:Morpholines / Q000008:administration & dosage / Q000627:therapeutic use; D009037:Motilin / Q000097:blood; D009853:Omeprazole / Q000008:administration & dosage / Q000627:therapeutic use; D013004:Somatostatin / Q000097:blood; D004561:Transcutaneous Electric Nerve Stimulation / Q000379:methods*; D016896:Treatment Outcome
D001549:Benzamides; D005765:Gastrointestinal Agents; D009025:Morpholines; D013004:Somatostatin; D009037:Motilin; D004294:Domperidone; C062720:mosapride; D009853:Omeprazole