Cavin fever: regulating caveolae.
SDPR is a new regulator of caveolae biogenesis. SDPR overexpression results in increased caveolae size and leads to the formation of caveolae-derived tubules containing Shiga toxin. SDPR may therefore be a membrane curvature-inducing component of caveolae.
Nabi
Ivan R
IR
D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism / Q000502:physiology; D021941:Caveolae / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism / Q000502:physiology; D008954:Models, Biological; D028044:Phosphate-Binding Proteins; D016601:RNA-Binding Proteins / Q000378:metabolism / Q000502:physiology
C497835:CAVIN1 protein, human; C112303:CAVIN2 protein, human; D002352:Carrier Proteins; D008565:Membrane Proteins; D028044:Phosphate-Binding Proteins; D016601:RNA-Binding Proteins