title: [Predisposition to alcohol and drug consumption in schizophrenia-vulnerable people].
abstract: BACKGROUND
  A large amount of current schizophrenia research has been centered on the understanding of its etiological mechanisms and the detection of vulnerability markers in people at risk. This vulnerability called schizotypy can be identified in people not affected by the illness at the clinical level.
  
  
  OBJECTIVE
  To check if the schizotypic personality disorder as a vulnerability marker of the disorders in the schizophrenic spectrum predicts the presence of psychopathologic symptoms and alcohol and drugs intake.
  
  
  METHODS
  From a population of 442 university students tested with the Schizotypy Personality Questionnaire (SPQ), it was selected a sample including people scoring on the 20% superior and inferior for the characteristic factors of schizophrenia corresponding to positive symptoms (cognitive-perceptual), negative symptoms (interpersonal) and thought disorder (disorganized). Furthermore, it was evaluated the presence of psychopathological problems and symptoms. Also, the participants gave information about alcohol and drugs intake as a passive coping strategy with stress.
  
  
  RESULTS
  Compared with the low scored, subjects with high scores in the schizotypic personality disorder showed a significant increase in the presence of psychopathological problems and symptoms and a higher alcohol and drugs intake. That occurs mainly when those scores are found in symptoms associated to thought disorder and negative symptoms as lack of interest in social activities and emotional flattening.
  
  
  CONCLUSIONS
  The schizotypic personality disorder, in accordance with its role as vulnerability factor, seems to co-occur with a higher volume of somatic and psychopathologic symptoms, and alcohol and drugs intake.
authors: Departamento de Personalidad, Evaluación y Tratamiento Psicológicos, Facultad de Psicología, Campus de Guajara, Universidad de La Laguna, Tenerife, España. afumero@ull.es
authors: A
authors: A
authors: Fumero
authors: C
authors: C
authors: Santamaría
authors: G
authors: G
authors: Navarrete
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000235:genetics / Q000503:physiopathology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000235:genetics / Q000503:physiopathology; D011795:Surveys and Questionnaires; D055815:Young Adult