"Clickable" elastins: elastin-like polypeptides functionalized with azide or alkyne groups.
Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide-alkyne cycloaddition to a variety of (bio)molecules.
Teeuwen
Rosalie L M
RL
Radboud University Nijmegen, Institute for Molecules and Materials, Department of Organic Chemistry, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands.
van Berkel
Sander S
SS
van Dulmen
Tim H H
TH
Schoffelen
Sanne
S
Meeuwissen
Silvie A
SA
Zuilhof
Han
H
de Wolf
Frits A
FA
van Hest
Jan C M
JC
D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D004549:Elastin / Q000737:chemistry* / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D005456:Fluorescent Dyes; D009842:Oligopeptides / Q000737:chemistry* / Q000235:genetics; D015202:Protein Engineering
D000480:Alkynes; D001386:Azides; D005456:Fluorescent Dyes; D009842:Oligopeptides; D003300:Copper; D004549:Elastin