The levonorgestrel intrauterine system as an alternative to hysterectomy for the treatment of idiopathic menorrhagia.
OBJECTIVE
Prospective, observational study to determine the percentage of hysterectomies cancelled after a year of treatment with levonorgestrel intrauterine system (LNG-IUS) among women diagnosed with idiopathic menorrhagia.


RESULTS
Eighty-two women with a mean age of 44.3 + or - 4.9 were enrolled. Throughout 1-year follow-up, progressive and significant reduction was observed in number of days of bleeding (8.9 + or - 4.0 vs. 5.0 + or - 5.4), number of sanitary measures (29.3 + or - 19.4 vs. 8.1 + or - 10.8) and percentage of patients having intense/very intense bleeding (98.8%vs. 6.4%). Duration of menstrual cycle significantly increased from 26.9 + or - 5.5 to 52.6 + or - 33.6 days. Significant improvement in overall health-related quality of life was achieved. Patient satisfaction was good/very good in 70.7%. Considering only women who attended 12-month visit satisfaction reached 91.2%. 75.6% of scheduled hysterectomies were cancelled. Adverse effects were recorded in less than 40% of patients with no significant differences between visits. Adverse effects led to premature discontinuation of treatment in seven cases. No serious adverse effects were encountered.


RESULTS
LNG-IUS meets the effectiveness and tolerability criteria for being considered as a first choice treatment option for women with idiopathic menorrhagia. Its use may contribute to decrease the large number of hysterectomies scheduled in Spain.
Goñi
Alvaro Zapico
AZ
Príncipe de Asturias Hospital, Faculty of Medicine of Alcalá University, Alcalá de Henares, Madrid 28805, Spain. azapicog@sego.es
Lacruz
Ramón Lanzón
RL
Paricio
Juan José Parilla
JJ
Hernández Rivas
Francisco J
FJ
D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects; D016912:Levonorgestrel / Q000627:therapeutic use*; D008595:Menorrhagia / Q000628:therapy*; D008597:Menstrual Cycle; D008875:Middle Aged; D017060:Patient Satisfaction; D018579:Patient Selection; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
D016912:Levonorgestrel