Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study.
Whether hepatitis C virus coinfection might accelerate atherosclerosis in HIV-infected individuals is unclear. We examined the relationship of HIV and hepatitis C virus with carotid artery intima media thickness and the presence of carotid plaques in the Women's Interagency HIV Study. Hepatitis C virus infection was not associated with greater carotid artery intima media thickness after adjustment for demographic and traditional cardiovascular risk factors. Further follow-up is needed to clarify whether HIV/hepatitis C virus coinfection may be associated with a greater risk of carotid plaque.
Tien
Phyllis C
PC
Department of Medicine, University of California, San Francisco, CA 94121, USA. ptien@ucsf.edu
Schneider
Michael F
MF
Cole
Stephen R
SR
Cohen
Mardge H
MH
Glesby
Marshall J
MJ
Lazar
Jason
J
Young
Mary
M
Mack
Wendy
W
Hodis
Howard N
HN
Kaplan
Robert C
RC
D000328:Adult; D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000821:virology*; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000821:virology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D014463:Ultrasonography