title: Persistent truncus arteriosus with dissecting aneurysm and subsequent cardiac tamponade in a lamb.
abstract: The present case report describes the necropsy and histopathology findings of a 3-week-old lamb with persistent truncus arteriosus (PTA). This rare cardiac malformation was characterized by the presence of a common arterial trunk arising from the right ventricle and overriding a ventricular septal defect. The pulmonary arteries originated from a short common trunk from this PTA, which subsequently continued as the thoracic aorta. The death of the lamb was attributed to a rupture of the PTA with subsequent cardiac tamponade. Histologically, a dissecting aneurysm with elastic fiber fragmentation in the wall of the PTA was identified as the underlying pathologic condition. Altered hemodynamic forces with subsequent secondary vasculopathy, as well as congenital primary vasculopathies, should be considered as an underlying pathogenetic mechanism.
authors: Department of Pathology, Clinic for Swine and Small Ruminants, University of Veterinary Medicine, Buenteweg 17, D-30559 Hanover, Germany.
authors: Verena
authors: V
authors: Haist
authors: Alexandra
authors: A
authors: von Altrock
authors: Andreas
authors: A
authors: Beineke
mesh_terms: D000784:Aortic Dissection / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002305:Cardiac Tamponade / Q000473:pathology / Q000662:veterinary*; D009206:Myocardium / Q000473:pathology; D012756:Sheep; D012757:Sheep Diseases / Q000151:congenital* / Q000473:pathology; D014339:Truncus Arteriosus, Persistent / Q000473:pathology / Q000662:veterinary*