Macrophagic myofascitis associated with rheumatoid arthritis.
Macrophagic myofascitis (MMF) is an unusual inflammatory myopathy characterized by muscle infiltration by macrophages and lymphocytes. Here, we describe a case of MMF which is associated with rheumatoid arthritis. A 53-year-old Japanese rheumatoid arthritis (RA) patient presented with focal tenderness of lower extremities. Magnetic resonance imaging showed evidence of myofascitis involving fascias of anterior tibialis muscle. Muscle biopsy showed a unique pathological pattern of MMF. MMF is known to be associated with vaccination containing aluminum. However, our case was not related to aluminum containing vaccinations and etiologies are unknown. The possible link needs to be discussed.
Migita
Kiyoshi
K
Department of Rheumatology and General Internal Medicine, Clinical Research Center, NHO Nagasaki Medical Center, Kubara 2-1001-1, Omura, 856-8652, Japan. migita@nmc.hosp.go.jp
Ueda-Nakata
Ruka
R
Masuda
Tomoko
T
Miyashita
Taichiro
T
Koga
Tomohiro
T
Izumi
Yasumori
Y
Ichinose
Katsuhiro
K
Ezaki
Hironori
H
Ito
Masahiro
M
Motomura
Masakatsu
M
Eguchi
Katsumi
K
D001172:Arthritis, Rheumatoid / Q000150:complications*; D001706:Biopsy; D005205:Fascia / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007866:Leg / Q000473:pathology / Q000503:physiopathology; D008264:Macrophages / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D018482:Muscle, Skeletal / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D009209:Myofascial Pain Syndromes / Q000276:immunology* / Q000473:pathology* / Q000503:physiopathology; D009220:Myositis / Q000276:immunology* / Q000473:pathology* / Q000503:physiopathology; D011239:Prednisolone / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D011239:Prednisolone; D016559:Tacrolimus