title: Loss of NF-kappaB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor beta signaling.
authors: Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.
authors: Nigar
authors: N
authors: Fatma
authors: Eri
authors: E
authors: Kubo
authors: Yoshihiro
authors: Y
authors: Takamura
authors: Keiichi
authors: K
authors: Ishihara
authors: Claudia
authors: C
authors: Garcia
authors: David C
authors: DC
authors: Beebe
authors: Dhirendra P
authors: DP
authors: Singh
mesh_terms: D000818:Animals; D001483:Base Sequence; D015153:Blotting, Western; D002460:Cell Line; D003593:Cytoplasm / Q000378:metabolism; D024202:Electrophoretic Mobility Shift Assay; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D016328:NF-kappa B / Q000378:metabolism*; D018384:Oxidative Stress; D054465:Peroxiredoxin VI / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics; D015531:Radioimmunoprecipitation Assay; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D051900:Smad3 Protein / Q000235:genetics / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000494:pharmacology*
chemical_list: D016328:NF-kappa B; D017382:Reactive Oxygen Species; D051900:Smad3 Protein; D016212:Transforming Growth Factor beta; D054465:Peroxiredoxin VI