title: Spectral analysis of field potential recordings by deep brain stimulation electrode for localization of subthalamic nucleus in patients with Parkinson's disease.
abstract: OBJECTIVE
  Spectral analysis of local field potential (LFP) recorded by deep brain stimulation (DBS) electrode around the subthalamic nucleus (STN) in patients with Parkinson's disease was performed.
  
  
  METHODS
  The borders of the STN were determined by microelectrode recording. The most eligible trajectory for the sensorimotor area of the STN was used for LFP recording while advancing the DBS electrode.
  
  
  RESULTS
  The low-frequency LFP power (theta- to beta-band) increased from a few millimeters above the dorsal border of the STN defined by microelectrode recording; however, the low-frequency power kept the same level beyond the ventral border of the STN. Only high beta-power showed close correlation to the dorsal and ventral borders of the STN.
  
  
  CONCLUSIONS
  A spectral power analysis of LFP recording by DBS electrode helps with the final confirmation of the dorsal and ventral borders of the STN of Parkinson's disease in DBS implantation surgery.
authors: Division of Digital Patient, Digital Medicine Initiative, Kyushu University, Higashi-ku, Fukuoka, Japan. yamiyagi@digital.med.kyushu-u.ac.jp
authors: Yasushi
authors: Y
authors: Miyagi
authors: Tsuyoshi
authors: T
authors: Okamoto
authors: Takato
authors: T
authors: Morioka
authors: Shozo
authors: S
authors: Tobimatsu
authors: Yoshitaka
authors: Y
authors: Nakanishi
authors: Kazuyuki
authors: K
authors: Aihara
authors: Kimiaki
authors: K
authors: Hashiguchi
authors: Nobuya
authors: N
authors: Murakami
authors: Fumiaki
authors: F
authors: Yoshida
authors: Kazuhiro
authors: K
authors: Samura
authors: Shinji
authors: S
authors: Nagata
authors: Tomio
authors: T
authors: Sasaki
mesh_terms: D000368:Aged; D001931:Brain Mapping / Q000379:methods; D046690:Deep Brain Stimulation / Q000379:methods*; D004567:Electrodes, Implanted; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology* / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000033:anatomy & histology / Q000502:physiology*