title: Intralesional amphotericin B in a cat with refractory localised sporotrichosis.
abstract: The present report concerns a case of sporotrichosis in a 3-year-old male crossbred cat. After 9 months of oral itraconazole (20mg/kg) therapy, all skin lesions had resolved with the exception of a single nodular lesion located on the bridge of the nose. Therefore, a combined therapy that included intralesional (IL) amphotericin B (1mg/kg) was started. The lesion resolved completely after three weekly administrations of IL amphotericin B, given in concert with oral itraconazole. The cat remains well 1 year after discontinuing therapy, with no signs of recurrence.
authors: Laboratory of Clinical Research on Dermatozoonosis in Domestic Animals, Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation (Fiocruz), Av Brasil, 4365 - Manguinhos, 21045-900, Rio de Janeiro - RJ, Brazil. isabella.dib@ipec.fiocruz.br
authors: Isabella D F
authors: ID
authors: Gremião
authors: Tânia Maria P
authors: TM
authors: Schubach
authors: Sandro A
authors: SA
authors: Pereira
authors: Aline M
authors: AM
authors: Rodrigues
authors: Adriana R
authors: AR
authors: Chaves
authors: Mônica B L
authors: MB
authors: Barros
mesh_terms: D000666:Amphotericin B / Q000008:administration & dosage*; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage*; D001938:Brazil; D002371:Cat Diseases / Q000188:drug therapy* / Q000382:microbiology; D002415:Cats; D015552:Injections, Intralesional / Q000662:veterinary; D008297:Male; D009668:Nose Diseases / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary; D013174:Sporotrichosis / Q000188:drug therapy / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B