[Effects of antimicrobial drugs on soil microbial respiration].
The effects on soil microbial respiration of sulfonamides, tetracyclines, macrolides and so on were studied using the direct absorption method. The results show sulfamethazine, sulfamethoxazole, chlortetracycline, tetracycline, tylosin and trimethoprim inhibit soil respiration 34.33%, 34.43%, 2.71%, 3.08%, 7.13%, 38.08% respectively. Sulfamethoxazole and trimethoprim have the highest inhibition rates among all the antibiotics. In early incubation period (0-2 d), the concentrations above 10 mg x kg(-1) of sulfamethazine, sulfamethoxazole and trimethoprim remarkably decrease soil CO2 emission. The effects of these antibiotics vary with their concentrations too. Sulfamethoxazole and trimethoprim show good dose-response relationships. According to the standard of pesticide safety evaluation protocol, the six antibiotics pose a little risk to soil microbial environment.
Liu
Feng
F
State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China. liufeng10@126.com
Ying
Guang-Guo
GG
Zhou
Qi-Xing
QX
Tao
Ran
R
Su
Hao-Chang
HC
Li
Xu
X
D000890:Anti-Infective Agents / Q000032:analysis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000378:metabolism*; D018407:Bacterial Physiological Phenomena / Q000187:drug effects; D019069:Cell Respiration / Q000187:drug effects; D004784:Environmental Monitoring; D012987:Soil / Q000032:analysis*; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000032:analysis* / Q000494:pharmacology; D013411:Sulfadiazine / Q000032:analysis / Q000494:pharmacology; D013412:Sulfadimethoxine / Q000032:analysis / Q000494:pharmacology
D000890:Anti-Infective Agents; D012987:Soil; D012989:Soil Pollutants; D013411:Sulfadiazine; D013412:Sulfadimethoxine