Effects of endurance training on cardiorespiratory fitness and substrate partitioning in postmenopausal women.
We examined the effect of endurance training on energy substrate partitioning during rest and exercise in postmenopausal women. Ten healthy sedentary (55 +/- 1 years old) subjects completed 12 weeks of endurance exercise training on a cycle ergometer (5 d/wk, 1 h/d, 65% peak oxygen consumption [Vo(2)peak]). Whole-body energy substrate oxidation was determined by indirect calorimetry during 90 minutes of rest and 60 minutes of cycle ergometer exercise. Subjects were studied at 65% Vo(2)peak before training and after training at the same absolute exercise intensity (same absolute workload as 65% of pretraining Vo(2)peak) and same relative exercise intensity (65% of posttraining Vo(2)peak). After training, Vo(2)peak increased by 16.3% +/- 3.9% and resting heart rate decreased by 4 beats per minute (P < .05). During exercise at same absolute intensity, mean arterial pressure decreased by 8 mm Hg (P < .05), heart rate decreased by 19 beats per minute (P < .05), energy derived from carbohydrate decreased by 9.6%, and the energy derived from lipid increased by 9.2% (P < .05). Lactate concentration was lower at the same absolute and relative exercise intensities (P < .05). Changes in substrate partitioning during exercise were accomplished without changes in dietary composition, body weight, or body composition. We conclude that endurance training in healthy postmenopausal women who remain in energy balance results in many of the classic cardiopulmonary training effects, decreases the reliance on carbohydrate, and increases lipid oxidation during a given submaximal exercise task without a reduction in body weight.
Zarins
Zinta A
ZA
Exercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA 94720, USA.
Wallis
Gareth A
GA
Faghihnia
Nastaran
N
Johnson
Matthew L
ML
Fattor
Jill A
JA
Horning
Michael A
MA
Brooks
George A
GA
D001481:Basal Metabolism / Q000502:physiology; D001786:Blood Glucose / Q000378:metabolism; D002320:Cardiovascular Physiological Phenomena; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008875:Middle Aged; D010084:Oxidation-Reduction; D010807:Physical Endurance / Q000502:physiology; D010809:Physical Fitness / Q000502:physiology*; D017698:Postmenopause / Q000378:metabolism*; D012119:Respiration; D012146:Rest / Q000502:physiology
D001786:Blood Glucose; D019344:Lactic Acid