Rhodium-catalyzed asymmetric conjugate alkynylation of enones with alkynylsilanols.
Asymmetric conjugate alkynylation of alpha,beta-unsaturated ketones with (triisopropylsilyl)ethynylsilanols giving beta-alkynylketones took place in high yields with high enantioselectivity in the presence of chiral rhodium catalysts.
Nishimura
Takahiro
T
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp
Tokuji
Sumito
S
Sawano
Takahiro
T
Hayashi
Tamio
T