title: Foetal peak systolic velocity in the middle cerebral artery: an Asian reference range.
abstract: BACKGROUND
  The aim of this study was to establish reference values of peak systolic blood flow velocity measurement in the foetal middle cerebral artery (MCA-PSV) in the local Asian obstetric population and to compare our reference ranges with those of previously-published studies.
  
  
  METHODS
  329 normal pregnant women attending the outpatient antenatal clinics of the Department of Obstetrics and Gynaecology in the Singapore General Hospital underwent Doppler ultrasonography at least once between 16 and 40 weeks' gestation. The blood flow velocity recordings from the foetal middle cerebral artery were obtained. New reference ranges were constructed by regressing each parameter on gestational age.
  
  
  RESULTS
  New reference ranges for foetal middle cerebral artery with gestation were constructed for an Asian population. Our reference curves were compared with that of a previously-constructed one.
  
  
  CONCLUSIONS
  MCA-PSV increases with advancing gestational age. There appear to be differences between Asian and non-Asian reference ranges for MCA-PSV.
authors: Clinical Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Block MD11, #02-02, 10 Medical Drive, Singapore. kennytan@nus.edu.sg
authors: K B L
authors: KB
authors: Tan
authors: S M C
authors: SM
authors: Fook-Chong
authors: S L
authors: SL
authors: Lee
authors: L K
authors: LK
authors: Tan
mesh_terms: D001208:Asia; D044466:Asian People; D001783:Blood Flow Velocity; D005260:Female; D005333:Fetus / Q000098:blood supply; D005865:Gestational Age; D006801:Humans; D020768:Middle Cerebral Artery / Q000196:embryology* / Q000473:pathology*; D009774:Obstetrics / Q000379:methods; D011247:Pregnancy; D012016:Reference Values; D012846:Singapore; D013599:Systole; D013997:Time Factors; D016216:Ultrasonography, Prenatal / Q000379:methods