title: Systemic sclerosis in an Afro-Caribbean population: a review of demographic and clinical features.
abstract: OBJECTIVE
  To assess the clinical and selected demographic features of patients with systemic sclerosis (SS) seen over a 10-year period at the Rheumatology service of the Queen Elizabeth Hospital, Barbados. To compare these data with what is known to obtain in other ethnic populations.
  
  
  METHODS
  A chart review involving all patients who were found to have SS based on the American College of Rheumatology clinical criteria was conducted between 1996 and 2006.
  
  
  RESULTS
  Twenty-seven patients with SS were identified in this predominantly Afro-Caribbean population. The prevalent and incident cases numbered 10 and 17 respectively. Twenty-six of these patients were female and the mean age at diagnosis was 37.3 years. Diffuse cutaneous involvement was seen in 63% of cases and limited cutaneous involvement in 37%. The most common clinical features in descending order of frequency were Raynaud's phenomenon, gastroesophageal reflux, pigmentary skin changes, digital pitting/ulceration, telangiectasia and pulmonary disease.
  
  
  CONCLUSIONS
  In a predominantly Afro-Caribbean population, SS was uncommonly seen, had a marked female preponderance and an earlier age of onset than that seen in Caucasian populations. As expected, diffuse disease was the more common subtype and digital pitting, pigmentary skin changes, and pulmonary disease were amongst the most frequent clinical features. Telangiectasia were found more frequently than the literature suggests is typical for patients of African descent.
authors: School of Clinical Medicine and Research, The University of the West Indies, Queen Elizabeth Hospital, Bridgetown, Barbados. cflower@caribsurf.com
authors: C
authors: C
authors: Flower
authors: C
authors: C
authors: Nwankwo
mesh_terms: D000293:Adolescent; D000328:Adult; D001460:Barbados / Q000453:epidemiology; D044383:Black People; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012595:Scleroderma, Systemic / Q000208:ethnology* / Q000503:physiopathology; D055815:Young Adult