Lupus erythematosus tumidus in Japan: a case report and a review of the literature.
We report here the case of a 48-year-old Japanese woman showing plaque-forming scattered indurative papules on her face, buttock and extremities. Histological examination revealed a large amount of interstitial mucin deposition, and negative direct immunofluorescence was observed. The provocative phototesting reproduced the skin lesion, and the patient was diagnosed with lupus erythematosus tumidus (LET). A review of ten LET cases previously reported in Japan revealed that all of these cases had clinicopathological features similar to those reported for European cases, although not all of the former fully satisfied the European criteria.
Nishiyama
Mizuho
M
Department of Dermatology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan. m-nishi@wakayama-med.ac.jp
Kanazawa
Nobuo
N
Hiroi
Akihisa
A
Furukawa
Fukumi
F
D005260:Female; D006801:Humans; D007564:Japan; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome; D014466:Ultraviolet Rays