Role of PACAP in controlling granule cell migration.
Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuropeptide, regulates a wide variety of cellular functions, but little is known about its role in neuronal cell migration. Recent studies revealed that PACAP has short-term, cortical layer-specific effects on neuronal cell migration. In this article, we focus on the role of PACAP in controlling the migration of cerebellar granule cells.
Cameron
Donald Bryant
DB
Department of Neurosciences, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Raoult
Emilie
E
Galas
Ludovic
L
Jiang
Yulan
Y
Lee
Kimberly
K
Hu
Taofang
T
Vaudry
David
D
Komuro
Hitoshi
H
D000818:Animals; D002465:Cell Movement / Q000187:drug effects / Q000502:physiology*; D002531:Cerebellum / Q000166:cytology*; D015870:Gene Expression / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000494:pharmacology; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide / Q000819:agonists / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology*; D051236:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide / Q000378:metabolism
D018377:Neurotransmitter Agents; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide; D051236:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide