title: Evaluation of sensitivity of different organisms to cefepime and tazobactum (megapime XP) in comparison to cefepime and ceftazidime.
abstract: The present study was carried out to evaluate the sensitivity of different organisms to cefepime and tazobactum (megapime XP) in comparison to cefepime and ceftazidime. Samples were collected from clinical specimens and micro-organisms were isolated from clinical specimens. Strains of micro-organisms isolated from clinical specimens were identified using standard methods like morphology, colony characteristics and biochemical reactions. Sensitivity was carried out using Kirby Bauer disc diffusion method. Minimum inhibitory concentrations (MICs) for all the antibiotics were carried out as per guideline of Clinical and Laboratory Standard Institute (CLSI). The results of the study demonstrated that cefepime and tazobactum exhibits good activity against Gram +ve and Gram-ve organisms.
authors: Alkem Laboratories Ltd, Mumbai 400013.
authors: R B
authors: RB
authors: Pal
authors: Paramita
authors: P
authors: Pal
authors: Veena
authors: V
authors: Venkatesh
authors: K P
authors: KP
authors: Kulkarni
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D000077723:Cefepime; D002442:Ceftazidime / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D004338:Drug Combinations; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D010397:Penicillanic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D000078142:Tazobactam
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D004338:Drug Combinations; D000077723:Cefepime; D010397:Penicillanic Acid; D002442:Ceftazidime; D000078142:Tazobactam