title: Anterior cruciate ligament reconstruction with bone-patellar tendon-bone autograft versus allograft.
abstract: OBJECTIVE
  The purpose of this study was to analyze the clinical outcome of arthroscopic anterior cruciate ligament (ACL) reconstruction with bone-patellar tendon-bone autograft versus allograft.
  
  
  METHODS
  Between May 2000 and June 2004, 172 patients undergoing arthroscopic bone-patellar tendon-bone ACL reconstruction were prospectively randomized into autograft (n = 86) or allograft (n = 86) groups. The senior surgeon performed all operations using the same surgical technique. Each fixation was performed by means of an interference screw. Patients were evaluated preoperatively and postoperatively at follow-up. Of the patients, 156 (76 in the autograft group and 80 in the allograft group) were available for full evaluation. Evaluations included a detailed history, physical examination, functional knee ligament testing, KT-2000 arthrometer testing (MEDmetric, San Diego, CA), Harner's vertical jump and Daniel's 1-leg hop tests, Lysholm score, Tegner score, International Knee Documentation Committee standard evaluation form, Cincinnati knee score, and radiograph.
  
  
  RESULTS
  Demographic data were comparable between groups. The mean follow-up was 5.6 years for both groups. There were no statistically significant differences according to evaluations of outcome between the 2 groups except that patients in the allograft group had a shorter operation time and longer fever time postoperatively compared with the autograft group. The postoperative infection rates were 0% and 1.25% for the autograft group and allograft group, respectively. There was a significant difference (P < .05) in the development of osteoarthritis between the operated knee in comparison to the contralateral knee according to radiographs. However, no significant difference was found between the 2 groups at the final follow-up examination (P > .05).
  
  
  CONCLUSIONS
  Both groups of patients achieved almost the same satisfactory outcomes after a mean of 5.6 years of follow-up. Allograft is a reasonable alternative to autograft for ACL reconstruction.
  
  
  METHODS
  Level II, prospective comparative study.
authors: Department of Orthopaedics, Healthy Physical Examination Center, The Affiliated Hospital of Medical College, Qingdao University, Qingdao, Shandong, China. sunkang_qy@yahoo.com.cn
authors: Kang
authors: K
authors: Sun
authors: Shao-qi
authors: SQ
authors: Tian
authors: Ji-hua
authors: JH
authors: Zhang
authors: Chang-suo
authors: CS
authors: Xia
authors: Cai-long
authors: CL
authors: Zhang
authors: Teng-bo
authors: TB
authors: Yu
mesh_terms: D000328:Adult; D000368:Aged; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D001182:Arthroscopy / Q000379:methods; D001265:Athletic Injuries / Q000601:surgery; D050376:Bone-Patellar Tendon-Bone Grafting / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007718:Knee Injuries / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D020127:Recovery of Function; D012421:Rupture / Q000601:surgery; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult