[A pilot study on the diagnosis of laryngopharyngeal reflux diseases].
OBJECTIVE
To study the value of the reflux symptom index (RSI) and reflux finding score (RFS) in laryngopharyngeal reflux disease (LPRD).


METHODS
Twenty-five patients with RSI scores > 13 or RFS scores > 7 and sixteen patients with RSI scores > 13 and RFS scores > 7 were suspected as LPRD. Forty one patients with the RSI scores > 13 and/or RFS scores > 7 were suspected as LPRD, 15 patients with the RSI scores <or= 13 and RFS scores <or= 7 were regarded as control group. All the patients had 24-hour dual probe pH monitoring. Twenty-five patients with positive pH monitoring hand received anti-reflux treatment with omeprazole for 3 months, and then the RSI and RFS was estimated again.


RESULTS
The RSI and RFS scoring had high consistent with the results of pH monitoring (Kappa = 0.43, u = 3.48, P < 0.01), especially if RSI scores > 13 and RFS scores > 7 (Kappa = 0.55, u = 3.06, P < 0.01). There was a significant decreasing in RSI and RFS scoring in patients after anti-acid treatment for 3 months (t(RSI) = 8.838, P(RSI) = 0.000; t(RFS) = 5.695, P(RFS) = 0.000).


CONCLUSIONS
The RSI and RFS can be used as screening tool for laryngopharyngeal reflux diseases and as a simple method for evaluating the effectiveness of treatment.
Zhang
Li-Hong
LH
Department of Otorhinolaryngology, People's Hospital of Peking University, Beijing 100044, China. lihongzhang@vip.sina.com
Li
Na
N
Zheng
Hong-Wei
HW
Yu
Li-Sheng
LS
Fen
Gui-Jian
GJ
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D057045:Laryngopharyngeal Reflux / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011522:Protons
D011522:Protons