A treatment algorithm for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience.
During a 13-year period (from 1994 to 2007), in the Oral and Maxillofacial Surgery Department of the Pitié-Salpêtrière Hospital, 116 new cases of adult ameloblastomas, were analyzed for treatment composed against radiographic presentation, size, histological type. Follow-up and recurrence were also analyzed. Treatment was surgical consisting of enucleations (82%), segmental mandibulectomy (8.3%) resections (24.7%) 85% of them underwent reconstruction. The follow-up was documented for 97%. More than two recurrences occurred in 21% of the patients after the first enucleation: 66% with a "follicular" histological diagnosis. Lenthly, a therapeutic algorithm is suggested for adult ameloblastomas that underlines the importance of the conservative enucleation treatment as far as possible.
Escande
Catherine
C
Stomatology and Maxillofacial Surgery Department, Pitié-Salpêtrière University Hospital, Assistance Publique des Hôpitaux de Paris, Pierre et Marie Curie-Paris6 University, Paris F-75013, France. catherine.escande@psl.aphp.fr
Chaine
André
A
Menard
Philippe
P
Ernenwein
Didier
D
Ghoul
Sonia
S
Bouattour
Ayman
A
Berdal
Ariane
A
Bertrand
Jacques-Charles
JC
Ruhin-Poncet
Blandine
B
D000328:Adult; D000465:Algorithms; D000564:Ameloblastoma / Q000175:diagnosis / Q000628:therapy*; D002985:Clinical Protocols; D003663:Decision Trees; D006801:Humans; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000628:therapy*; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000628:therapy*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control* / Q000628:therapy; D019647:Oral Surgical Procedures / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome