Palladium-catalyzed direct alkynylation of C-H bonds in benzenes.
Palladium-catalyzed ortho-alkynylation of aromatic C-H bonds in anilides is described. Preliminary mechanistic studies reveal that electrophilic palladation is involved. Synthetic elaborations of alkynylated products are also demonstrated.
Tobisu
Mamoru
M
Frontier Research Base for Global Young Researchers, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. tobisu@chem.eng.osaka-u.ac.jp
Ano
Yusuke
Y
Chatani
Naoto
N