Perioperative anaphylaxis.
The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents represent the most frequently involved substances, followed by latex and antibiotics, but every drug or substance used may be involved. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests and specific IgE or basophil activation assays.
Mertes
P M
PM
Service d'Anesthésie-Réanimation Chirurgicale, CHU de Nancy, Hôpital Central, 29 Avenue de Lattre de Tassigny, Nancy Cedex 54035, France. pm.mertes@chu-nancy.fr
Lambert
M
M
Guéant-Rodriguez
R M
RM
Aimone-Gastin
I
I
Mouton-Faivre
C
C
Moneret-Vautrin
D A
DA
Guéant
J L
JL
Malinovsky
J M
JM
Demoly
P
P
D000485:Allergens / Q000276:immunology; D000707:Anaphylaxis; D000768:Anesthesia, General; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D015549:Basophil Degranulation Test; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D007073:Immunoglobulin E / Q000097:blood; D015994:Incidence; D007431:Intraoperative Complications / Q000276:immunology / Q000517:prevention & control; D007840:Latex / Q000276:immunology; D020315:Latex Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects; D019990:Perioperative Care; D053802:Tryptases / Q000097:blood
D000485:Allergens; D000900:Anti-Bacterial Agents; D007840:Latex; D009466:Neuromuscular Blocking Agents; D007073:Immunoglobulin E; D053802:Tryptases