title: Aggravation of mitral regurgitation by calcium administration in a patient with hypertrophic cardiomyopathy during liver transplantation: a case report.
abstract: Aggravation of mitral regurgitation (MR) due to left ventricular outflow tract obstruction (LVOTO) is likely to occur during liver transplantation in cirrhotic patients with hypertrophic cardiomyopathy (HCMP). Moreover, calcium administration following severe hypocalcemia due to inadequate citrate metabolism and massive transfusion may induce MR aggravation with LVOTO in such patients. Herein we have described a cirrhotic patient with HCMP in whom MR was aggravated due to LVOTO resulting from inadvertent rapid administration of calcium during liver transplantation.
authors: Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors: J H
authors: JH
authors: Chin
authors: Y K
authors: YK
authors: Kim
authors: D K
authors: DK
authors: Choi
authors: W J
authors: WJ
authors: Shin
authors: G S
authors: GS
authors: Hwang
mesh_terms: D002122:Calcium Chloride / Q000009:adverse effects*; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D017548:Echocardiography, Transesophageal; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology; D007431:Intraoperative Complications / Q000139:chemically induced*; D016031:Liver Transplantation / Q000379:methods*; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000139:chemically induced*; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000139:chemically induced*
chemical_list: D002122:Calcium Chloride