Genetic and epigenetic marker-based DNA test of stool is a promising approach for colorectal cancer screening.
Colorectal cancer (CRC) is one of the most common malignancies and leading cause of cancer-related deaths in the world.1 However, it may be treated effectively by surgical removal of the cancerous tissue if detected at early stages. Conventional tools for screening CRC are either invasive or inaccurate. Therefore, there is an urgent need to develop a reliable screening tools for CRC to significantly reduce its morbidity. In this regard, a novel DNA markers-based detection in stool is emerging as a promising approach.
An
Sung Whan
SW
Cancer Metastasis Research Center, Yonsei University College of Medicine, Seoul, Korea. sungwhan@genomictree.com
Kim
Nam Kyu
NK
Chung
Hyun Cheol
HC
D014408:Biomarkers, Tumor / Q000235:genetics; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D044127:Epigenesis, Genetic / Q000235:genetics*; D005243:Feces; D005819:Genetic Markers / Q000235:genetics*
D014408:Biomarkers, Tumor; D005819:Genetic Markers