[Not Available].
BACKGROUND
The healing potential of platelet growth factors has generated interest in using Platelet-Rich Plasma (PRP) in ridge preservation procedures. A canine study was performed to determine if extraction sites treated with platelet-rich fibrin matrix (PRFM) exhibit enhanced healing compared to sites treated with non-viable materials.


METHODS
Four dog's extraction sockets were treated individually with PRFM, PRFM and membrane, Demineralized Freeze-Dried Bone Allograft (DFDBA) and membrane, PRFM and DFDBA, and untreated control. Treatment sequencing permitted clinical and histologic evaluation of healing at 10 days, 2, 3, 6 and 12 weeks.


RESULTS
Healing was more rapid in the PRFM and PRFM and membrane sites. By 3 weeks those sockets had osseous fill. Sites containing DFDBA had little new bone at 6 weeks. By 12 weeks those sockets had osseous fill but DFDBA particles were still noted in coronal areas.


CONCLUSIONS
PRFM alone may be the best graft for ridge preservation procedures.


CONCLUSIONS
faster healing, and elimination of disadvantages involved in using barrier membranes.
Simon
B I
BI
New Jersey Dental School, USA. simonbi@umdnj.edu
Zatcoff
A L
AL
Kong
J J W
JJ
O'Connell
S M
SM