[Analgetic property of nonspecific thalamic nuclei].
Neruronal activity evoked by pain impulsation in the specific thalamic nuclei and sensorimotor cortex has been recorded in cat. The following data were obtained. Evoked nociceptive neuronal activity was inhibited by stimulation of the nonspecific thalamic nuclei. An antinociceptive impact of the nonspecific thalamic nuclei on the specific thalamic units was fulfilled by both direct and thalamo-cortico-thalamic pathways. Stimulation of the antinociceptive regions of the nonspecific thalamic nuclei abolished evoked nociceptive activity of the cortical units, elicited by both peripheral noxious stimulus and stimulation of the ventro-postero-medial thalamic nuclei. This indicates that the nonspecific thalamic nuclei inhibit the cortical activity on the thalamic, as well as, on the cortical level.
Bekaia
G L
GL
Kvachadze
I D
ID
Pruidze
M V
MV
Sakvarelidze
Z A
ZA
Khutsisvili
K V
KV
D000698:Analgesia; D000818:Animals; D002415:Cats; D009619:Nociceptors / Q000502:physiology*; D010146:Pain / Q000503:physiopathology*; D013787:Thalamic Nuclei / Q000503:physiopathology*