title: Intraoperative floppy iris syndrome (IFIS): a practical approach to medical and surgical considerations in cataract extractions.
abstract: Intraoperative floppy iris syndrome (IFIS) during cataract surgery is characterized by iris fluttering, iris prolapse towards the incisions, and a progressive pupillary constriction leading to high rates of complications. The syndrome has been reported following the treatment of benign prostatic hyperplasia with α-1(a) adrenergic receptor inhibitors, especially tamsulosin. The present paper describes the syndrome and discusses its pharmacological background. Several techniques to prevent and to deal with the syndrome are presented.
authors: Department of Ophthalmology, Frederiksberg University Hospital, Frederiksberg, Denmark. allanstorr@dadlnet.dk
authors: Allan
authors: A
authors: Storr-Paulsen
authors: Jens Christian
authors: JC
authors: Nørregaard
authors: Kim Kamp
authors: KK
authors: Børme
authors: Allan Boye
authors: AB
authors: Larsen
authors: Jesper
authors: J
authors: Thulesen
mesh_terms: D058668:Adrenergic alpha-1 Receptor Antagonists; D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications; D007499:Iris Diseases / Q000139:chemically induced / Q000517:prevention & control*; D008297:Male; D018918:Phacoemulsification; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D011680:Pupil / Q000187:drug effects; D013577:Syndrome
chemical_list: D058668:Adrenergic alpha-1 Receptor Antagonists; D000317:Adrenergic alpha-Antagonists; D000970:Antineoplastic Agents