title: Grade II atypical choroid plexus papilloma with normal karyotype.
abstract: OBJECTIVE
  Cytogenetic studies of atypical choroid plexus papillomas (CPP) have been poorly described. In the present report, the cytogenetic investigation of an atypical CPP occurring in an infant is detailed.
  
  
  METHODS
  CPP chromosome preparations were analyzed by giemsa-trypsin-banding (GTG-banding) and comparative genome hybridization (CGH).
  
  
  RESULTS
  Conventional karyotype analysis of tumor culture showed a normal chromosome complement. The results were confirmed by CGH, showing normal hybridization patterns for the sample.
  
  
  CONCLUSIONS
  To date, the few atypical CPPs described in the literature have shown disparate cytogenetic information. This is the first report of a normal chromosome complement in atypical CPP. The heterogenic genetic features observed in these small series may reflect the diverse genetic background of choroid plexus tumors in children.
authors: Division of Pediatric Oncology, Department of Pediatrics, University of São Paulo, São Paulo, Brazil. marsol@rge.fmrp.usp.br
authors: María Sol
authors: MS
authors: Brassesco
authors: Elvis Terci
authors: ET
authors: Valera
authors: Aline Paixão
authors: AP
authors: Becker
authors: Ricardo Santos
authors: RS
authors: Oliveira
authors: Carlos Alberto
authors: CA
authors: Scrideli
authors: Hélio Rubens
authors: HR
authors: Machado
authors: Luiz Gonzaga
authors: LG
authors: Tone
mesh_terms: D002831:Choroid Plexus / Q000601:surgery; D016545:Choroid Plexus Neoplasms / Q000235:genetics / Q000601:surgery; D003582:Cytogenetics; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D020288:Papilloma, Choroid Plexus / Q000235:genetics* / Q000601:surgery; D016896:Treatment Outcome