title: The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry.
abstract: In Austria, registration of malignant brain tumours is legally mandatory, whereas benign and borderline tumours are not reported. The Austrian Brain Tumour Registry (ABTR) was initiated under the auspices of the Austrian Society of Neuropathology for the registration of malignant and non-malignant brain tumours. All Austrian neuropathology units involved in brain tumour diagnostics contribute data on primary brain tumours. Non-microscopically verified cases are added by the Austrian National Cancer Registry to ensure a population-based dataset. In 2005, we registered a total of 1,688 newly diagnosed primary brain tumours in a population of 8.2 million inhabitants with an overall age-adjusted incidence rate of 18.1/100,000 person-years. Non-malignant cases constituted 866 cases (51.3%). The incidence rate was higher in females (18.6/100,000) as compared to males (17.8/100,000), while 95/1,688 (5.6%) cases were diagnosed in children (<18 years). The most common histology was meningioma (n = 504, 29.9%) followed by glioblastoma (n = 340, 20.1%) and pituitary adenoma (n = 151, 8.9%). Comparison with the Central Brain Tumor Registry of the United States (CBTRUS) database showed high congruency of findings. The ABTR model led by neuropathologists in collaboration with epidemiologists and the Austrian National Cancer Registry presents a cooperative way to establish a population-based brain tumour registry with high quality data. This setting links cancer registration to the mission of medical practice and research as defined by the World Medical Association in the Declaration of Helsinki. The continued operation of ABTR will aid in monitoring changes in incidence and in identifying regional disease clusters or geographic variations in brain tumour morbidity/mortality.
authors: Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.|Austrian Society of Neuropathology, Austria, Austria.
authors: Adelheid
authors: A
authors: Wöhrer
authors: Center of Public Health, Department of Epidemiology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
authors: Thomas
authors: T
authors: Waldhör
authors: Core Unit for Medical Statistics and Informatics, Section of Clinical Biometrics, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
authors: Harald
authors: H
authors: Heinzl
authors: Austrian National Cancer Registry, Statistics Austria, Guglgasse 13, 1110, Vienna, Austria.
authors: Monika
authors: M
authors: Hackl
authors: Department of Pathology, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030, Vienna, Austria.
authors: Johann
authors: J
authors: Feichtinger
authors: Department of Pathology, Feldkirch State Hospital, Carinagasse 47, 6807, Feldkirch, Austria.
authors: Ulrike
authors: U
authors: Gruber-Mösenbacher
authors: Institute of Pathology, State Hospital Klagenfurt, St. Veiter Strasse 47, 9020, Klagenfurt, Austria.
authors: Andreas
authors: A
authors: Kiefer
authors: Department of Pathology, Medical University of Innsbruck, Christoph-Probst-Platz Innrain 52, 6020, Innsbruck, Austria.
authors: Hans
authors: H
authors: Maier
authors: Department of Pathology and Neuropathology, State Neuropsychiatric Hospital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020, Linz, Austria.
authors: Reinhard
authors: R
authors: Motz
authors: Institute of Pathology, Danube Hospital, Langobardenstrasse 122, 1220, Vienna, Austria.
authors: Angelika
authors: A
authors: Reiner-Concin
authors: Department of Neurosurgery, Christian Doppler Clinic, Paracelsus Private Medical University, Strubergasse 21, 5020, Salzburg, Austria.
authors: Bernd
authors: B
authors: Richling
authors: Department of Neurology, Christian Doppler Clinic, Paracelsus Private Medical University, Strubergasse 21, 5020, Salzburg, Austria.
authors: Carmen
authors: C
authors: Idriceanu
authors: Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036, Graz, Austria.
authors: Michael
authors: M
authors: Scarpatetti
authors: Department of Clinical Pathology, General Hospital St. Pölten, Probst-Führer-Strasse 4, 3100, St. Pölten, Austria.
authors: Roland
authors: R
authors: Sedivy
authors: Department of Clinical Pathology, General Hospital St. Pölten, Probst-Führer-Strasse 4, 3100, St. Pölten, Austria.
authors: Hans-Christian
authors: HC
authors: Bankl
authors: Institute of Pathology, General Hospital Wiener Neustadt, Corvinusring 3-5, 2700, Wiener Neustadt, Austria.
authors: Wolfgang
authors: W
authors: Stiglbauer
authors: Department of Internal Medicine I, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
authors: Matthias
authors: M
authors: Preusser
authors: Task Force for Neurosurgical Oncology, Austrian Society of Neurosurgery, Austria.
authors: Karl
authors: K
authors: Rössler
authors: Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. johannes.hainfellner@meduniwien.ac.at.|Austrian Society of Neuropathology, Austria, Austria. johannes.hainfellner@meduniwien.ac.at.
authors: Johannes Andreas
authors: JA
authors: Hainfellner
mesh_terms: D000236:Adenoma / Q000453:epidemiology / Q000473:pathology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria / Q000453:epidemiology; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004806:Ependymoma / Q000453:epidemiology / Q000473:pathology; D005260:Female; D040362:Geographic Information Systems; D005909:Glioblastoma / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D015994:Incidence; D008297:Male; D008577:Meningeal Neoplasms / Q000453:epidemiology / Q000473:pathology; D008875:Middle Aged; D009837:Oligodendroglioma / Q000453:epidemiology / Q000473:pathology; D012042:Registries / Q000592:standards* / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D017678:Sex Distribution; D055815:Young Adult