Huntington disease and other choreas.
Chorea is defined as a syndrome characterized by brief, abrupt involuntary movements resulting from a continuous flow of random muscle contractions. There are genetic and non-genetic causes of chorea. The most common genetic cause of chorea is Huntington's disease (HD). Non-genetic forms of chorea include vascular choreas, auto-immune choreas, metabolic and toxic choreas, and drug-induced choreas. This chapter provides an overview of clinical features, pathogenesis and management of HD, other important genetic causes of chorea, Sydenham's chorea, other autoimmune choreas and vascular choreas.
Cardoso
Francisco
F
Internal Medicine Department, The Federal University of Minas Gerais, MG, Brazil. cardosofe@terra.com.br
D020274:Autoimmune Diseases of the Nervous System / Q000209:etiology / Q000235:genetics / Q000628:therapy; D002819:Chorea / Q000209:etiology / Q000235:genetics* / Q000628:therapy*; D006816:Huntington Disease / Q000209:etiology / Q000235:genetics* / Q000628:therapy*; D014652:Vascular Diseases / Q000209:etiology / Q000235:genetics / Q000628:therapy