title: Sedation and analgesia in the pediatric intensive care unit following laryngotracheal reconstruction.
abstract: BACKGROUND
  Children undergoing laryngotracheal reconstruction (LTR) may remain electively intubated in the pediatric intensive care unit (PICU) for several days following surgery to facilitate wound healing. These patients require sedation and analgesia with or without neuromuscular blockade in order to prevent excessive head and neck movement with resultant tension on the tracheal anastomosis. Achieving this level of immobility features in caring for these children.
  
  
  OBJECTIVE
  The aims of this article are to describe a variety of commonly used sedation and analgesic agents and to provide guidance as to their optimal use following LTR.
authors: Anesthesiology and Pediatrics, Department of Anesthesia, Stanford University School of Medicine, University Medical Center, 300 Pasteur Drive, Stanford, CA 94305-5640, USA. ham@stanford.edu
authors: Gregory B
authors: GB
authors: Hammer
mesh_terms: D000698:Analgesia; D000700:Analgesics / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation; D003422:Critical Care; D004361:Drug Tolerance; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007223:Infant; D015278:Intensive Care Units, Pediatric; D007830:Larynx / Q000601:surgery*; D009466:Neuromuscular Blocking Agents / Q000627:therapeutic use; D019651:Plastic Surgery Procedures; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology; D014132:Trachea / Q000601:surgery*
chemical_list: D000700:Analgesics; D006993:Hypnotics and Sedatives; D009466:Neuromuscular Blocking Agents