title: Treatise on the measurement of molecular masses with ion mobility spectrometry.
abstract: The ability to separate isotopes by high-resolution ion mobility spectrometry techniques is considered as a direct means for determining mass at ambient pressures. Calculations of peak shapes from the transport equation show that it should be possible to separate isotopes for low-mass ions (<200) by utilizing heavy collision gases and high-resolution ion mobility analyzers. The mass accuracy associated with this isotopic separation approach based on ion mobility separation is considered. Finally, we predict several isotopes that should be separable.
authors: Department of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47405, USA. stvalent@indiana.edu
authors: Stephen J
authors: SJ
authors: Valentine
authors: David E
authors: DE
authors: Clemmer
mesh_terms: D007477:Ions / Q000737:chemistry / Q000302:isolation & purification; D007536:Isomerism; D007554:Isotopes / Q000737:chemistry / Q000302:isolation & purification; D008956:Models, Chemical; D008970:Molecular Weight; D009038:Motion; D011312:Pressure; D013057:Spectrum Analysis / Q000379:methods*; D013696:Temperature
chemical_list: D007477:Ions; D007554:Isotopes