title: Three-dimensional quantitative imaging of retinal and choroidal blood flow velocity using joint Spectral and Time domain Optical Coherence Tomography.
abstract: Recently, joint Spectral and Time domain Optical Coherence Tomography (joint STdOCT) has been proposed to measure ocular blood flow velocity. Limitations of CCD technology allowed only for two-dimensional imaging at that time. In this paper we demonstrate fast three-dimensional STdOCT based on ultrahigh speed CMOS camera. Proposed method is straightforward, fully automatic and does not require any advanced image processing techniques. Three-dimensional distributions of axial velocity components of the blood in human eye vasculature are presented: in retinal and, for the first time, in choroidal layer. Different factors that affect quality of velocity images are discussed. Additionally, the quantitative measurement allows to observe a new interesting optical phenomenon - random Doppler shift in OCT signals that forms a vascular pattern at the depth of sclera.
authors: Institute of Physics, Nicolaus Copernicus University, Torun, Poland.
authors: Anna
authors: A
authors: Szkulmowska
authors: Maciej
authors: M
authors: Szkulmowski
authors: Daniel
authors: D
authors: Szlag
authors: Andrzej
authors: A
authors: Kowalczyk
authors: Maciej
authors: M
authors: Wojtkowski
mesh_terms: D000792:Angiography / Q000379:methods; D001331:Automation; D002829:Choroid / Q000098:blood supply*; D004867:Equipment Design; D005583:Fourier Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D007834:Lasers; D008962:Models, Theoretical; D055095:Optics and Photonics; D012171:Retinal Vessels / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods*