Evaluation of a new rapid antigen test using immunochromatography for detection of human metapneumovirus in comparison with real-time PCR assay.
A new rapid human metapneumovirus (hMPV) detection kit using immunochromatography (SAS hMPV test) was compared to real-time PCR for 224 nasal swab specimens, 96.4% of which were obtained from children of <15 years of age. The overall sensitivity and specificity were 82.3% and 93.8%, respectively, suggesting that this test is useful for pediatricians to diagnose hMPV infection in a clinical setting.
Matsuzaki
Yoko
Y
Course of Clinical Nursing, Yamagata University Faculty of Medicine, Iida-Nishi 2-2-2, Yamagata 990-9585, Japan. matuzaki@med.id.yamagata-u.ac.jp
Takashita
Emi
E
Okamoto
Michiko
M
Mizuta
Katsumi
K
Itagaki
Tsutomu
T
Katsushima
Fumio
F
Katsushima
Yuriko
Y
Nagai
Yukio
Y
Nishimura
Hidekazu
H
D000293:Adolescent; D000956:Antigens, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D029121:Metapneumovirus / Q000302:isolation & purification*; D009297:Nasal Mucosa / Q000821:virology; D018184:Paramyxoviridae Infections / Q000175:diagnosis*; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity
D000956:Antigens, Viral