[Hormones and osteoporosis update. Regulation of bone remodeling by adipokines].
The effect of adipokines, cytokines secreted from adipocytes, on bone remodelling has been intensively studied in recent years. Leptin, in a physiological manner, inhibits bone formation and stimulates bone resorption through the central relay. However, the role of other adipokines, such as adiponectin and resistin, on bone remodelling remains to be elucidated.
Takeda
Shu
S
Section of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, Keio Univeristy.
D017667:Adipocytes / Q000378:metabolism; D054392:Adipokines / Q000378:metabolism / Q000502:physiology*; D052242:Adiponectin; D000818:Animals; D016723:Bone Remodeling; D001862:Bone Resorption; D006801:Humans; D020738:Leptin / Q000502:physiology*; D010012:Osteogenesis; D052243:Resistin
D054392:Adipokines; D052242:Adiponectin; D020738:Leptin; D052243:Resistin