[The pharmacokinetic of drugs in elderly patients].
The use of pharmacotherapy in the elderly requires caution because of increasing with age drug sensitivity and risk of dangerous adverse effects. The process of ageing induce alteration in pharmacokinetics of drugs. Modifications affect practically each pharmacokinetic phase. Processes of distribution and, first of all, drug elimination are the most essential for clinical practice.
Jabłecka
Anna
A
Department of Clinical Pharmacology, Department of Cardiology, Medical University, Poznani, Poland. ajablecka@ump.edu.pl
Korzeniowska
Katarzyna
K
Smolarek
Iwona
I
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D010599:Pharmacokinetics