title: gPS navigates germ cells to pluripotency.
abstract: The establishment of pluripotent stem cell lines from explanted testes has been hampered by a poor understanding of their cellular origin. In this issue of Cell Stem Cell, Ko et al. (2009) reproducibly generate pluripotent cell lines from murine testes and unequivocally demonstrate their origin from spermatogonial stem cells.
authors: Massachusetts General Hospital Center for Regenerative Medicine and Cancer Center, Harvard Stem Cell Institute, Boston, MA 02114, USA. ngeijsen@mgh.harvard.edu
authors: Niels
authors: N
authors: Geijsen
authors: Konrad
authors: K
authors: Hochedlinger
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D005854:Germ Cells / Q000166:cytology* / Q000254:growth & development; D008297:Male; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology*; D013737:Testis / Q000166:cytology*