Mushroom poisoning from species of genus Inocybe (fiber head mushroom): a case series with exact species identification.
BACKGROUND
Many species of the genus Inocybe (family Cortinariaceae, higher Basidiomycetes) are muscarine-containing mycorrhizal mushrooms, ubiquitous around the world. The few published reports on the poisonous Inocybe mushrooms are often limited by the inadequate identification of the species. The clinical course of patients with typical muscarinic manifestations, in whom Inocybe spp. was unequivocally identified, is reported.


METHODS
Between November 2006 and January 2008 14 consecutive patients with typical muscarinic syndrome after mushroom ingestion were recorded. The clinical manifestations included combinations of nausea, vomiting, diarrhea, abdominal pain, hypersalivation, diaphoresis, tachycardia, bradycardia, hypotension, lacrimation, blurred vision, miosis, tremor, restlessness, flushing, and syncope. Time to onset of toxicity ranged between 15 min and 2 h after consumption, 5 h in one patient. Treatment was supportive, including intravenous fluids, antiemetics, and 1 mg atropine intravenously. Full recovery ensued within 12 h. In all the cases, an expert mycologist unequivocally identified the leftovers of the consumed mushrooms as Inocybe fastigiata, Inocybe geophylla, and Inocybe patouillardii.


CONCLUSIONS
In this case series of patients who ingested identified muscarine-containing mushrooms supportive treatment and atropine resulted in recovery in all cases.
Lurie
Yael
Y
Israel Poison Information Center, Rambam Health Care Campus, The Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Wasser
Solomon P
SP
Taha
Muhammad
M
Shehade
Haj
H
Nijim
Josef
J
Hoffmann
Yoav
Y
Basis
Fuad
F
Vardi
Moshe
M
Lavon
Ophir
O
Suaed
Suliman
S
Bisharat
Bishara
B
Bentur
Yedidia
Y
D000293:Adolescent; D000328:Adult; D000363:Agaricales / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D000932:Antiemetics / Q000627:therapeutic use; D001285:Atropine / Q000627:therapeutic use; D002648:Child; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D009116:Muscarine / Q000032:analysis; D009145:Mushroom Poisoning / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D013045:Species Specificity; D016896:Treatment Outcome; D014839:Vomiting / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D055815:Young Adult
D000932:Antiemetics; D001285:Atropine; D009116:Muscarine