title: Quantitative methods for food allergens: a review.
abstract: The quantitative detection of allergens in the food chain is a strategic health objective as the prevalence of allergy continues to rise. Food allergenicity is caused by proteins either in their native form or in forms resulting from food processing. Progress in mass spectrometry greatly opened up the field of proteomics. These advances are now available for the detection and the quantification of traces of allergenic proteins in complex mixtures, and complete the set of biological tests used until now, such as ELISA or PCR. We review methods classified according to their ability to simultaneously quantify and identify allergenic proteins and underline major advances in the mass-spectrometric methods.
authors: Mass Spectrometry Laboratory CART/GIGA-R, University of Liège, 4000 Liege, Belgium.
authors: Stéphanie
authors: S
authors: Kirsch
authors: Séverine
authors: S
authors: Fourdrilis
authors: Rowan
authors: R
authors: Dobson
authors: Marie-Louise
authors: ML
authors: Scippo
authors: Guy
authors: G
authors: Maghuin-Rogister
authors: Edwin
authors: E
authors: De Pauw
mesh_terms: D000485:Allergens / Q000032:analysis*; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D011506:Proteins / Q000032:analysis / Q000276:immunology; D040901:Proteomics / Q000379:methods
chemical_list: D000485:Allergens; D011506:Proteins