The physics behind the larger scale organization of DNA in eukaryotes.
In this paper, we discuss in detail the organization of chromatin during a cell cycle at several levels. We show that current experimental data on large-scale chromatin organization have not yet reached the level of precision to allow for detailed modeling. We speculate in some detail about the possible physics underlying the larger scale chromatin organization.
Emanuel
Marc
M
Instituut Lorentz voor de theoretische natuurkunde, Universiteit Leiden, PO Box 9506, NL-2300 RA Leiden, The Netherlands. emanuel@lorentz.leidenuniv.nl
Radja
Nima Hamedani
NH
Henriksson
Andreas
A
Schiessel
Helmut
H
D000818:Animals; D001665:Binding Sites; D002453:Cell Cycle; D002843:Chromatin; D004247:DNA / Q000737:chemistry*; D004548:Elasticity; D005057:Eukaryotic Cells / Q000737:chemistry*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D055672:Static Electricity
D002843:Chromatin; D004247:DNA