title: TEL me all.
abstract: Genetically engineered mouse models are powerful systems for dissecting the process of human leukemogenesis. In this issue of Cell Stem Cell, Schindler et al. (2009) describe the elegant use of this approach to dissect, but not completely replicate, the multistep pathogenesis of TEL-AML1(+) leukemia.
authors: Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada.
authors: Ivan
authors: I
authors: Sloma
authors: Connie J
authors: CJ
authors: Eaves
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics* / Q000378:metabolism; D018450:Disease Progression; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D051379:Mice; D023421:Models, Animal; D050596:Oncogene Fusion; D015514:Oncogene Proteins, Fusion / Q000235:genetics* / Q000378:metabolism; D009857:Oncogenes; D000097764:ETS Translocation Variant 6 Protein
chemical_list: D050676:Core Binding Factor Alpha 2 Subunit; D015514:Oncogene Proteins, Fusion; C102421:TEL-AML1 fusion protein; D000097764:ETS Translocation Variant 6 Protein