title: Resistance training does not contribute to improving the metabolic profile after a 6-month weight loss program in overweight and obese postmenopausal women.
abstract: BACKGROUND
  Limited data are available regarding the impact of caloric restriction (CR) in combination with resistance training (RT) on the metabolic profile of postmenopausal women.
  
  
  OBJECTIVE
  The objective of the study was to determine whether RT adds to CR in improving body composition and the metabolic profile.
  
  
  METHODS
  This was a 6-month, randomized, clinical trial.
  
  
  METHODS
  Patients included 107 postmenopausal women (body mass index >27 kg/m(2)).
  
  
  METHODS
  The intervention was a 6-month CR alone or in combination with a RT program.
  
  
  METHODS
  Fat mass (FM), lean body mass (LBM), abdominal sc fat and visceral fat, fasting lipids, insulin sensitivity, resting blood pressure, and inflammation markers were measured.
  
  
  RESULTS
  Both groups were similar at baseline and significantly decreased body weight, body mass index, FM, percent FM, abdominal sc fat, and visceral fat after the study (P < 0.001), with greater losses of percent FM and trunk FM in the CR + RT group (P < 0.05). LMB significantly decreased in the CR (-0.9 +/- 2.4 kg) and the CR+RT (-0.4 +/- 2.2 kg) groups (P < 0.005), with no difference between them. Both groups significantly improved plasma triglycerides, fasting insulin level, glucose disposal, and markers of the inflammation profile after weight loss (P < 0.05), with no difference between groups. No improvements were observed for the other variables of interest in both groups.
  
  
  CONCLUSIONS
  CR+RT was associated with greater losses in percent FM and trunk FM compared with CR alone. However, CR+RT was not associated with additional improvements in the metabolic profile compared with CR alone.
authors: Faculty of Physical Education and Sports, University of Sherbrooke, J1K 2R1, and Research Centre on Aging, Health and Social Services Centre, Sherbrooke University Institute of Geriatrics, Sherbrooke, Québec, Canada. martin.brochu@usherbrooke.ca
authors: Martin
authors: M
authors: Brochu
authors: Mircea Florin
authors: MF
authors: Malita
authors: Virginie
authors: V
authors: Messier
authors: Eric
authors: E
authors: Doucet
authors: Irene
authors: I
authors: Strychar
authors: Jean-Marc
authors: JM
authors: Lavoie
authors: Denis
authors: D
authors: Prud'homme
authors: Rémi
authors: R
authors: Rabasa-Lhoret
mesh_terms: D000368:Aged; D001823:Body Composition; D050218:Body Fat Distribution; D031204:Caloric Restriction; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D050177:Overweight / Q000378:metabolism*; D017698:Postmenopause; D055070:Resistance Training; D015431:Weight Loss
chemical_list: D005947:Glucose