Recent advances in carbohydrate-based vaccines.
Vaccinations provide an efficient and cost-effective way to combat devastating human diseases. Besides pathogenic protein markers, cell surface carbohydrates from biological sources are widely used as vaccines. Recently, synthetic immunogenic carbohydrate-protein conjugates have been advanced to vaccine candidates. Progress in the chemical synthesis of oligosaccharides and conjugation methods stimulated the development of novel carbohydrate-based vaccine candidates.
Hecht
Marie-Lyn
ML
Max-Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Stallforth
Pierre
P
Silva
Daniel Varón
DV
Adibekian
Alexander
A
Seeberger
Peter H
PH
D016915:AIDS Vaccines; D000818:Animals; D002241:Carbohydrates / Q000737:chemistry / Q000276:immunology*; D006001:Glycoconjugates / Q000737:chemistry / Q000276:immunology*; D006801:Humans; D014612:Vaccines / Q000737:chemistry / Q000276:immunology*
D016915:AIDS Vaccines; D002241:Carbohydrates; D006001:Glycoconjugates; D014612:Vaccines