Can lithium or valproate untie tangles in Alzheimer's disease?
Tariot
Pierre N
PN
Banner Alzheimer's Institute, Phoenix, AZ 85006, USA. Pierre.tariot@bannerhealth.com
Aisen
Paul S
PS
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D001921:Brain / Q000187:drug effects / Q000473:pathology; D004791:Enzyme Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D038362:Glycogen Synthase Kinase 3 / Q000037:antagonists & inhibitors; D006801:Humans; D016651:Lithium Carbonate / Q000009:adverse effects / Q000627:therapeutic use*; D016874:Neurofibrillary Tangles / Q000187:drug effects / Q000473:pathology; D010766:Phosphorylation / Q000187:drug effects; D058225:Plaque, Amyloid / Q000187:drug effects / Q000473:pathology; D016032:Randomized Controlled Trials as Topic; D014635:Valproic Acid / Q000009:adverse effects / Q000627:therapeutic use*; D016875:tau Proteins / Q000187:drug effects
D000927:Anticonvulsants; D004791:Enzyme Inhibitors; C054369:MAPT protein, human; D016875:tau Proteins; D016651:Lithium Carbonate; D014635:Valproic Acid; D038362:Glycogen Synthase Kinase 3