title: Ocular sarcoidosis in a Korean population.
abstract: The aim of current study was to evaluate the incidence and characteristics of ocular sarcoidosis in a Korean population. We conducted a retrospective study of 104 consecutive patients with biopsy-proven sarcoidosis seen at Asan Medical Center in Seoul, Korea, from 1993 to 2007. Medical records, photographs, and fluorescein angiograms were reviewed. Of 104 patients, 22 (21%) had intraocular involvement with female predominance (86%, M:F=3:19). Of the 39 eyes with ocular involvement, 16 (41%) eyes had isolated anterior uveitis, 12 (31%) eyes had intermediate uveitis, 6 eyes (15%) had panuveitis with retinal vasculitis, and 5 (13%) eyes had panuveitis with punched multifocal choroiditis. Mean duration of ophthalmologic follow-up was 62 months. All ocular inflammation was well managed with topical steroid and/or systemic steroid with relatively good final visual outcomes. Ocular complications such as cataract (12 eyes, 30%), glaucoma (6 eyes, 15%), vitreous opacity (1 eye, 3%), cystoid macular edema (3 eyes, 7%), neovascularization (2 eye, 5%), and epiretinal membrane (4 eye, 10%) were related to ocular sarcoidosis. In Korea, where sarcoidosis is very rare, our study indicates relatively low ocular and predominantly non posterior segment involvement with relatively good visual prognosis.
authors: Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
authors: Sun Young
authors: SY
authors: Lee
authors: Hee Gyung
authors: HG
authors: Lee
authors: Dong Soon
authors: DS
authors: Kim
authors: June-Gone
authors: JG
authors: Kim
authors: Hyewon
authors: H
authors: Chung
authors: Young Hee
authors: YH
authors: Yoon
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People; D002833:Choroiditis / Q000175:diagnosis; D005128:Eye Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D031300:Retinal Vasculitis / Q000175:diagnosis; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D013256:Steroids / Q000627:therapeutic use; D014606:Uveitis, Anterior / Q000175:diagnosis; D015867:Uveitis, Intermediate / Q000175:diagnosis
chemical_list: D013256:Steroids