title: Macrophagic myofascitis associated with rheumatoid arthritis.
abstract: Macrophagic myofascitis (MMF) is an unusual inflammatory myopathy characterized by muscle infiltration by macrophages and lymphocytes. Here, we describe a case of MMF which is associated with rheumatoid arthritis. A 53-year-old Japanese rheumatoid arthritis (RA) patient presented with focal tenderness of lower extremities. Magnetic resonance imaging showed evidence of myofascitis involving fascias of anterior tibialis muscle. Muscle biopsy showed a unique pathological pattern of MMF. MMF is known to be associated with vaccination containing aluminum. However, our case was not related to aluminum containing vaccinations and etiologies are unknown. The possible link needs to be discussed.
authors: Department of Rheumatology and General Internal Medicine, Clinical Research Center, NHO Nagasaki Medical Center, Kubara 2-1001-1, Omura, 856-8652, Japan. migita@nmc.hosp.go.jp
authors: Kiyoshi
authors: K
authors: Migita
authors: Ruka
authors: R
authors: Ueda-Nakata
authors: Tomoko
authors: T
authors: Masuda
authors: Taichiro
authors: T
authors: Miyashita
authors: Tomohiro
authors: T
authors: Koga
authors: Yasumori
authors: Y
authors: Izumi
authors: Katsuhiro
authors: K
authors: Ichinose
authors: Hironori
authors: H
authors: Ezaki
authors: Masahiro
authors: M
authors: Ito
authors: Masakatsu
authors: M
authors: Motomura
authors: Katsumi
authors: K
authors: Eguchi
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications*; D001706:Biopsy; D005205:Fascia / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007866:Leg / Q000473:pathology / Q000503:physiopathology; D008264:Macrophages / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D018482:Muscle, Skeletal / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D009209:Myofascial Pain Syndromes / Q000276:immunology* / Q000473:pathology* / Q000503:physiopathology; D009220:Myositis / Q000276:immunology* / Q000473:pathology* / Q000503:physiopathology; D011239:Prednisolone / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D011239:Prednisolone; D016559:Tacrolimus