title: Antimicrobial activity of Hymenaea martiana towards dermatophytes and Cryptococcus neoformans.
abstract: The biological activity of crude extract and fractions of Hymenaea martiana was evaluated against a panel of human pathogenic fungi. The crude extracts and hydroalcoholic fractions (E) showed a high activity against Cryptococcus neoformans species complex isolates with MICs between 2 and 64 μg ml(-1). The methanolic (C) and butanolic (D) fractions were the most active against Trichopyton rubrum, Trichopyton mentagrophytes and Microsporum canis with MICs between 8 and 256 μg ml(-1). None of the extracts was active against the yeast Malassezia furfur, Malassezia obtusa and Malassezia sympodialis.
authors: Laboratorio de Micologia da Universidade Federal de Goiás, Goiás, Brasil.
authors: Ana Cristina Machado
authors: AC
authors: de Souza
authors: Lucilia
authors: L
authors: Kato
authors: Cleuza Conceição
authors: CC
authors: da Silva
authors: Amanda Feitosa
authors: AF
authors: Cidade
authors: Cecilia Maria Alves
authors: CM
authors: de Oliveira
authors: Maria do Rosário Rodrigues
authors: Mdo R
authors: Silva
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects*; D003455:Cryptococcus neoformans / Q000187:drug effects*; D006801:Humans; D052597:Hymenaea / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts