title: Clinical efficacy of primary tumor volume measurements: comparison of different primary sites.
abstract: OBJECTIVE
  The purpose of study was to determine the clinical efficacy of primary tumor volume measurements of different primary sites in the oropharynx compared to the oral cavity.
  
  
  METHODS
  A retrospective analysis of 85 patients with oral cavity or oropharynx cancer. The tumor area was manually outlined from axial magnetic resonance (MR) series. The software calculated the tumor volumes, automatically. The values of the primary tumor volumes were then subdivided into separate groups (</=3,500 mm(3), >3,500 mm(3)).
  
  
  RESULTS
  The prognostic indicators were the cT and cN (oral cavity); age, primary site, cT, cN, and primary tumor volume (oropharynx) on the univariate analysis. There was no significant prognostic factor for oral cavity cancer on the multivariate analysis. Primary site, cN, and primary tumor volume were independent prognostic indicators for oropharynx cancer by multivariate analysis.
  
  
  CONCLUSIONS
  Primary tumor volume measurement is a reliable way to stratify outcome, and make up for the weak points in the American Joint Committee on Cancer staging system with oropharynx cancer.
authors: Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
authors: Eun-Jae
authors: EJ
authors: Chung
authors: Nam-Joon
authors: NJ
authors: Lee
authors: Seung-Kuk
authors: SK
authors: Baek
authors: Soon-Young
authors: SY
authors: Kwon
authors: Jeong-Soo
authors: JS
authors: Woo
authors: Kwang-Yoon
authors: KY
authors: Jung