title: Resection of a giant malignant mediastinal peripheral nerve sheath tumour under cardiopulmonary bypass.
abstract: Malignant peripheral nerve sheath tumour (MPNST) is a rare occurrence in the mediastinum. It is biologically aggressive and is generally resistant to chemoradiation therapy. The mainstay of treatment is complete surgical resection. We report a large MPNST which invaded into the adjacent aortic wall in a 50-year-old man. Extensive resection, which included aortic reconstruction under cardiopulmonary bypass and deep hypothermic arrest, was necessary for a good long-term outcome.
authors: Department of Cardiothoracic Surgery, National Heart Centre, Mistri Wing, 17 Third Hospital Avenue, Singapore. bottle1001@yahoo.com
authors: J W
authors: JW
authors: Su
authors: Y L
authors: YL
authors: Chua
authors: B H
authors: BH
authors: Ong
authors: C H
authors: CH
authors: Lim
mesh_terms: D002315:Cardiopulmonary Bypass; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000601:surgery*; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis / Q000601:surgery*; D013514:Surgical Procedures, Operative; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome