title: A new Borrelia species defined by multilocus sequence analysis of housekeeping genes.
abstract: Analysis of Lyme borreliosis (LB) spirochetes, using a novel multilocus sequence analysis scheme, revealed that OspA serotype 4 strains (a rodent-associated ecotype) of Borrelia garinii were sufficiently genetically distinct from bird-associated B. garinii strains to deserve species status. We suggest that OspA serotype 4 strains be raised to species status and named Borrelia bavariensis sp. nov. The rooted phylogenetic trees provide novel insights into the evolutionary history of LB spirochetes.
authors: Department of Biology and Biochemistry, University of Bath, 3 South, Claverton Down, Bath BA2 7AY, United Kingdom. gm250@bath.ac.uk
authors: Gabriele
authors: G
authors: Margos
authors: Stephanie A
authors: SA
authors: Vollmer
authors: Muriel
authors: M
authors: Cornet
authors: Martine
authors: M
authors: Garnier
authors: Volker
authors: V
authors: Fingerle
authors: Bettina
authors: B
authors: Wilske
authors: Antra
authors: A
authors: Bormane
authors: Liliana
authors: L
authors: Vitorino
authors: Margarida
authors: M
authors: Collares-Pereira
authors: Michel
authors: M
authors: Drancourt
authors: Klaus
authors: K
authors: Kurtenbach
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000235:genetics; D000954:Antigens, Surface / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D001428:Bacterial Vaccines / Q000235:genetics; D001717:Birds / Q000382:microbiology; D001898:Borrelia / Q000145:classification* / Q000235:genetics; D015748:Borrelia burgdorferi Group / Q000145:classification / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000235:genetics; D006801:Humans; D018884:Ixodes / Q000382:microbiology; D008074:Lipoproteins / Q000235:genetics; D008193:Lyme Disease / Q000382:microbiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012377:Rodentia / Q000382:microbiology; D017422:Sequence Analysis, DNA; D012703:Serotyping; D013045:Species Specificity
chemical_list: D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D021903:DNA, Ribosomal Spacer; D008074:Lipoproteins; C072045:OspA protein; C079616:OspC protein