title: The impact of Le Fort I advancement and bilateral sagittal split osteotomy setback on ventilation during sleep.
abstract: The impact of orthognathic surgery for class III malocclusion on ventilation during sleep was examined using a comparison of pre- and post-surgical respiratory parameters. 21 patients with both maxillary hypoplasia and mandibular excess underwent Le Fort I osteotomy and advancement together with bilateral sagittal split osteotomy (BSSO) setback. Respiratory parameters, ECG and position of the body were monitored before surgery and postoperatively after the fixation removal (mean 8.5 months). Average Le Fort I advancement was 4.44 mm, BSSO setback was 4.96 mm. Generally, the orthognathic procedure worsened breathing function during sleep, as reflected in significant increase of index of flow limitations and decrease in oxygen saturation. The posterior airways space decreased to 75% of its original volume, the distance between mandibular plane and hyoid bone increased to 133%. The results indicate that bimaxillary surgery for class III malocclusion increased upper airway resistance. A young person would probably be able to balance such a decline in respiratory function using different adaptive mechanisms, but the potential impact of orthognathic surgery on the upper airways should be incorporated in a treatment plan.
authors: Department of Oral and Maxillofacial Surgery, First Faculty of Medicine, Charles University, Prague, Czech Republic.
authors: R
authors: R
authors: Foltán
authors: J
authors: J
authors: Hoffmannová
authors: F
authors: F
authors: Donev
authors: M
authors: M
authors: Vlk
authors: J
authors: J
authors: Sedý
authors: R
authors: R
authors: Kufa
authors: O
authors: O
authors: Bulik
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology*; D056151:Airway Remodeling; D000403:Airway Resistance; D002508:Cephalometry; D005260:Female; D006801:Humans; D008297:Male; D008313:Malocclusion, Angle Class III / Q000601:surgery*; D008334:Mandible / Q000601:surgery*; D056948:Orthognathic Surgical Procedures / Q000009:adverse effects*; D010027:Osteotomy / Q000009:adverse effects; D019340:Osteotomy, Le Fort / Q000009:adverse effects*; D017286:Polysomnography; D012123:Pulmonary Ventilation; D020181:Sleep Apnea, Obstructive / Q000209:etiology*; D055815:Young Adult