Guideline for using growth hormone in paediatric patients in South Africa: treatment of growth hormone deficiency and other growth disorders.
The Paediatric and Adolescent Endocrine and Diabetes Society of South Africa (PAEDS-SA) recommends, in line with other international groups, that growth hormone (GH) therapy be considered for children and adolescents with significantly short stature and poor growth velocity in the following instances: GH deficiency; Turner syndrome; Prader-Willi syndrome; small-for-gestational-age children with failure of catch-up growth; idiopathic short stature; and chronic renal insufficiency. We have produced treatment guidelines for the use of GH, designed to allow flexibility to determine coverage on a case-by-case basis. We further recommend that when used for growth promotion, GH therapy should be initiated and monitored by, or in consultation with, a paediatric endocrinologist.
Segal
David
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Centre for Diabetes and Endocrinology, 18 Eton Road, Parktown, Johannesburg 2198. david.segal@wits.ac.za
D002648:Child; D002675:Child, Preschool; D019317:Evidence-Based Medicine; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D013006:Growth Hormone / Q000172:deficiency / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D010372:Pediatrics / Q000379:methods* / Q000592:standards*; D011218:Prader-Willi Syndrome / Q000188:drug therapy; D051436:Renal Insufficiency, Chronic; D013019:South Africa; D016896:Treatment Outcome; D014424:Turner Syndrome / Q000188:drug therapy
D013006:Growth Hormone