title: Motor nerve-conduction studies in obstetric brachial plexopathy for a selection of patients with a poor outcome.
abstract: BACKGROUND
  The criteria and timing for nerve surgery in infants with obstetric brachial plexopathy remain controversial. Our aim was to develop a new method for early prognostic assessment to assist this decision process.
  
  
  METHODS
  Fifty-four patients with unilateral obstetric brachial plexopathy who were ten to sixty days old underwent bilateral motor-nerve-conduction studies of the axillary, musculocutaneous, proximal radial, distal radial, median, and ulnar nerves. The ratio between the amplitude of the compound muscle action potential of the affected limb and that of the healthy side was called the axonal viability index. The patients were followed and classified in three groups according to the clinical outcome. We analyzed the receiver operating characteristic curve of each index to define the best cutoff point to detect patients with a poor recovery.
  
  
  RESULTS
  The best cutoff points on the axonal viability index for each nerve (and its sensitivity and specificity) were <10% (88% and 89%, respectively) for the axillary nerve, 0% (88% and 73%) for the musculocutaneous nerve, <20% (82% and 97%) for the proximal radial nerve, <50% (82% and 97%) for the distal radial nerve, and <50% (59% and 97%) for the ulnar nerve. The indices from the proximal radial, distal radial, and ulnar nerves had better specificities compared with the most frequently used clinical criterion: absence of biceps function at three months of age.
  
  
  CONCLUSIONS
  The axonal viability index yields an earlier and more specific prognostic estimation of obstetric brachial plexopathy than does the clinical criterion of biceps function, and we believe it may be useful in determining surgical indications in these patients.
authors: University of São Paulo Medical School Clinics Hospital, São Paulo, Brazil. carlos.heise@fleury.com.br
authors: Carlos O
authors: CO
authors: Heise
authors: Mario G
authors: MG
authors: Siqueira
authors: Roberto S
authors: RS
authors: Martins
authors: José Luiz D
authors: JL
authors: Gherpelli
mesh_terms: D000200:Action Potentials; D001720:Birth Injuries / Q000175:diagnosis* / Q000601:surgery; D001917:Brachial Plexus / Q000503:physiopathology*; D020516:Brachial Plexus Neuropathies / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D053580:Muscle Strength; D009431:Neural Conduction; D018579:Patient Selection; D011379:Prognosis; D012372:ROC Curve; D012680:Sensitivity and Specificity; D034941:Upper Extremity / Q000294:innervation