5-Fluorouracil-induced coronary vasospasm.
Cardiotoxicity due to 5-fluorouracil involves rare and life-threatening cardiotoxic events occurring in less than 1% of the patients. We describe a case of coronary vasospasm due to parenteral 5-fluorouracil, which did not recur with oral capecitabine. We also give a brief review of the cardiotoxicity of 5-fluorouracil, its treatment and prevention.
Bathina
Jaya D
JD
Department of Cardiology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.
Yusuf
Syed Wamique
SW
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D054715:Cardiotoxins / Q000009:adverse effects*; D003329:Coronary Vasospasm / Q000139:chemically induced*; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans
D000964:Antimetabolites, Antineoplastic; D054715:Cardiotoxins; D005472:Fluorouracil