title: Predictable enzymatic glycosylation.
abstract: An innovative approach for manipulating glycosyltransferase-catalyzed glycosylation has now been developed (Truman et al.). Created using a domain-swapping strategy, these chimeric glycotransferases have predictable substrate specificity and may lead to the breakthrough developments in the preparation of carbohydrate-containing molecules of biological interest.
authors: Department of Chemistry and Biochemistry, Utah State University, 0300 Old Main Hill, Logan, UT 84322-0300, USA. tom.chang@usu.edu
authors: Cheng-Wei Tom
authors: CW
authors: Chang
mesh_terms: D006031:Glycosylation; D016695:Glycosyltransferases / Q000737:chemistry* / Q000378:metabolism; D011237:Predictive Value of Tests; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D011993:Recombinant Fusion Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
chemical_list: D011993:Recombinant Fusion Proteins; D016695:Glycosyltransferases