title: Management of pellucid marginal corneal degeneration with simultaneous customized photorefractive keratectomy and collagen crosslinking.
abstract: A 34-year-old woman had simultaneous photorefractive keratectomy and corneal collagen crosslinking with riboflavin-ultraviolet-A irradiation for the treatment of progressive pellucid marginal corneal degeneration in both eyes. No intraoperative or early postoperative complications occurred. Twelve months postoperatively, the uncorrected visual acuity was assessed at 20/40 in both eyes compared with counting fingers preoperatively. The corrected visual acuity also improved from 20/50 and 20/63 to 20/25 and 20/32 in the right eye and left eye, respectively. Corneal topography revealed a significant improvement in both eyes. Despite the encouraging results, longer follow-up is necessary to confirm the stability of the results.
authors: Institute of Vision and Optics, University of Crete, Crete, Greece.
authors: George D
authors: GD
authors: Kymionis
authors: Alexandra E
authors: AE
authors: Karavitaki
authors: George A
authors: GA
authors: Kounis
authors: Dimitra M
authors: DM
authors: Portaliou
authors: Sonia H
authors: SH
authors: Yoo
authors: Ioannis G
authors: IG
authors: Pallikaris
mesh_terms: D000328:Adult; D003094:Collagen / Q000378:metabolism*; D003315:Cornea / Q000378:metabolism* / Q000503:physiopathology; D003317:Corneal Dystrophies, Hereditary / Q000503:physiopathology / Q000601:surgery*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D010778:Photochemotherapy / Q000379:methods*; D018903:Photorefractive Keratectomy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011183:Postoperative Complications; D012256:Riboflavin / Q000627:therapeutic use; D014466:Ultraviolet Rays; D014792:Visual Acuity / Q000502:physiology
chemical_list: D017319:Photosensitizing Agents; D003094:Collagen; D012256:Riboflavin