Glycosylation of fluorophenols by plant cell cultures.
Fluoroaromatic compounds are used as agrochemicals and released into environment as pollutants. Glycosylation of 2-, 3-, and 4-fluorophenols using plant cell cultures of Nicotiana tabacum was investigated to elucidate their potential to metabolize these compounds. Cultured N. tabacum cells converted 2-fluorophenol into its beta-glucoside (60%) and beta-gentiobioside (10%). 4-Fluorophenol was also glycosylated to its beta-glucoside (32%) and beta-gentiobioside (6%) by N. tabacum cells. On the other hand, N. tabacum glycosylated 3-fluorophenol to beta-glucoside (17%).
Shimoda
Kei
K
Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Kubota
Naoji
N
Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Kondo
Yoko
Y
Department of Life Science, Okayama University of Science, 1-1 Ridai-cho, Okayama 700-0005, Japan.
Sato
Daisuke
D
Department of Life Science, Okayama University of Science, 1-1 Ridai-cho, Okayama 700-0005, Japan.
Hamada
Hiroki
H
Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
D002478:Cells, Cultured; D052918:Environmental Restoration and Remediation / Q000379:methods; D006031:Glycosylation; D010575:Pesticides / Q000378:metabolism; D010636:Phenols / Q000378:metabolism*; D059828:Plant Cells / Q000737:chemistry / Q000378:metabolism; D012989:Soil Pollutants / Q000378:metabolism; D014026:Nicotiana / Q000737:chemistry / Q000378:metabolism*
D010575:Pesticides; D010636:Phenols; D012989:Soil Pollutants; C106880:4-fluorophenol; C487839:2-fluorophenol; C085046:3-fluorophenol