title: Extraventricular subependymal giant cell tumor in a child with tuberous sclerosis complex.
abstract: Subependymal giant cell tumors (SGCTs) are observed in 5-20% of patients with tuberous sclerosis complex (TSC) but account for approximately 25% of neurological morbidity. The authors report the case of a 7-year-old girl with TSC and multiple cortical tubers who presented with worsening seizures in the context of the rapid growth of a cystic, calcified, extraventricular SGCT in the right frontal lobe, initially thought to represent a cortical tuber. The tumor and surrounding tubers were excised, and clinical seizures resolved. This is the first report of an extraventricular SGCT in a child with TSC outside the neonatal period.
authors: Department of Neurosurgery, New York University School of Medicine and NYU Langone Medical Center, New York, New York 10016, USA. robert.bollo@nyumc.org
authors: Robert J
authors: RJ
authors: Bollo
authors: Jonathan L
authors: JL
authors: Berliner
authors: Ingeborg
authors: I
authors: Fischer
authors: Daniel K
authors: DK
authors: Miles
authors: Elizabeth A
authors: EA
authors: Thiele
authors: David
authors: D
authors: Zagzag
authors: Howard L
authors: HL
authors: Weiner
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D005625:Frontal Lobe / Q000473:pathology* / Q000601:surgery; D005870:Giant Cell Tumors / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D012640:Seizures / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000150:complications* / Q000473:pathology