Invasive inflammatory myofibroblastic tumor of the lung.
Inflammatory myofibroblastic tumor (IMT) of the lung is a rare tumor but it should be considered when dealing with primary lung tumors in children, adolescents, and nonsmoking adults. It is, from a pathologic point of view, a benign tumor composed of a spindle cell proliferation and inflammatory cells. Its clinical behavior, however, is variable with a benign evolution at one, and a malignant evolution with recurrent and metastatic disease at the other end of the spectrum. Diagnosis is very difficult and often only possible after resection of the tumor. We present a case of pulmonary IMT in a 15-year-old male with malignant features on radiographic and F-Fluoro-deoxyglucose positron emission tomography imaging. Pathogenesis, pathology findings, clinical behavior, and imaging of pulmonary IMT are briefly discussed.
van den Heuvel
Daniel A
DA
Department of Radiology, St Antonius Hospital, Nieuwegein, The Netherlands. d.van.den.heuvel@antonius.net
Keijsers
Ruth G
RG
van Es
Hendrik W
HW
Bootsma
Gerben P
GP
de Bruin
Peter C
PC
Schramel
Franz M
FM
van Heesewijk
Johannes P
JP
D000293:Adolescent; D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008297:Male; D013902:Radiography, Thoracic; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18