Statin-like principles of bergamot fruit (Citrus bergamia): isolation of 3-hydroxymethylglutaryl flavonoid glycosides.
The 3-hydroxy-3-methylglutaryl neohesperidosides of hesperetin (brutieridin, 1) and naringenin (melitidin, 2) were isolated and detected from the fruits of bergamot (Citrus bergamia). The structures of these compounds were determined by spectroscopic and chemical methods.
Di Donna
Leonardo
L
Dipartimento di Chimica, Universita della Calabria, Via P. Bucci, Arcavacata di Rende, Italy.
De Luca
Giuseppina
G
Mazzotti
Fabio
F
Napoli
Anna
A
Salerno
Raffaele
R
Taverna
Domenico
D
Sindona
Giovanni
G
D002957:Citrus / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D006027:Glycosides; D006569:Hesperidin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
D044950:Flavanones; D005419:Flavonoids; D006027:Glycosides; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; C543779:brutieridin; C543780:melitidin; D006569:Hesperidin; C005273:naringenin; C013015:hesperetin