title: Total synthesis of pteridic acids A and B.
abstract: The total synthesis of pteridic acids A and B is reported. The convergent asymmetric synthesis involved the use of a diastereoselective ethyl ketone aldol reaction followed by an efficient spiroketalization and provided pteridic acids A and B in 2.9% and 2.8% overall yield, respectively.
authors: Institute of Chemistry, University of Campinas, UNICAMP, P.O. Box 6154 13084-971, Campinas, SP, Brazil. ldias@iqm.unicamp.br
authors: Luiz C
authors: LC
authors: Dias
authors: Airton G
authors: AG
authors: Salles
mesh_terms: D006538:Heptanoic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006538:Heptanoic Acids; D013141:Spiro Compounds; C467219:pteridic acid A; C467220:pteridic acid B