[Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea].
OBJECTIVE
To determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples.


METHODS
28 samples from 28 suspected cases (22 fecal samples, 3 vomitus samples, 3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomplished of 5 positive samples.


RESULTS
160 of 5694 population were ill with an attack rate of 2.81%. The peak period was 7-9, March. 14 of 28 samples were tested Norovirus positive.Sequencing and phylogenetic analysis showed Norovirus type GII/4 was the causative agent and it had highest identity (97. 9%) with epidemic strain 2006b.


CONCLUSIONS
The epidemic event ofinfectious diarrhea were caused by GII/4 Norovirus strains.
Liu
Yun-zhi
YZ
Center for Disease Control Hunan Pronice, Changsha 410005, China.
Huang
Yi-wei
YW
Jin
Miao
M
Zhang
Hong
H
Liu
Fu-qiang
FQ
Wang
Jing
J
Hu
Shi-xiong
SX
Ou
Xin-hua
XH
Duan
Zhao-jun
ZJ
D004196:Disease Outbreaks; D004403:Dysentery / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics; D005243:Feces / Q000821:virology*; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D017720:Molecular Epidemiology; D029322:Norovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction
D012367:RNA, Viral