title: Time trends and regional differences in the prevalence of HIV infection among women attending antenatal clinics in 2 provinces in Cameroon.
abstract: BACKGROUND
  HIV prevalence time trends vary in sub-Saharan African countries. In the present study, we studied time trends and regional differences in the prevalence of HIV infection among women attending antenatal care clinics (ANC) in 7 sites located in 2 provinces in Cameroon.
  
  
  METHODS
  As part of ANC, 16,626 women consented to HIV testing from 2000 to 2006. Sociodemographic and risk factor information was collected during the initial 3 years of the study. This information was aggregated within sites and used as site-level covariate in multilevel logistic regression analysis.
  
  
  RESULTS
  HIV prevalence decreased significantly in women younger than 20 years from 13% in 2000 to 5% in 2006. Age-specific prevalence varied among the sites, with a peak prevalence occurring more often at a higher age in 2004-2006 versus 2000-2003, suggesting a reduction of HIV incidence over time. There was a substantial heterogeneity across sites in HIV prevalence, which was lower in sites where women had earlier sexual debut and were less well educated.
  
  
  CONCLUSIONS
  ANC surveillance indicates a decreasing trend in HIV prevalence in the studied sites in Cameroon. Cultural differences might have accounted for the heterogeneity of HIV infection observed across sites, which call for tailored interventions.
authors: Department of Public Health Medicine, School of Public Health, University of Bielefeld, Bielefeld, Germany.
authors: Seraphin
authors: S
authors: Kuate
authors: Rafael T
authors: RT
authors: Mikolajczyk
authors: Gideon W
authors: GW
authors: Forgwei
authors: Pius M
authors: PM
authors: Tih
authors: Thomas K
authors: TK
authors: Welty
authors: Mirjam
authors: M
authors: Kretzschmar
mesh_terms: D000293:Adolescent; D000328:Adult; D002163:Cameroon / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000517:prevention & control*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D015995:Prevalence; D013997:Time Factors; D055815:Young Adult