Can we improve fixation and outcomes in the treatment of femoral neck fractures? The use of pharmaceuticals.
Femoral neck fracture rates are on the rise with an estimated 500,000 occurring annually by 2040. Despite the mainstay of open reduction and internal fixation, nonunion rates of up to 33% have been reported for displaced femoral neck fractures. Recently, increasing attention has been focused upon the role of osteobiologics to stimulate fracture repair. This article looks at the role of these anabolic compounds and discusses their potential future roles in augmenting the treatment of this condition.
Kakar
Sanjeev
S
Department of Orthopaedic Surgery, Boston University Medical Center, Boston, MA 02118, USA.
Little
David
D
Einhorn
Thomas A
TA
D045930:Anabolic Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D019317:Evidence-Based Medicine; D005265:Femoral Neck Fractures / Q000175:diagnosis* / Q000628:therapy*; D005593:Fracture Fixation, Internal / Q000639:trends*; D006801:Humans
D045930:Anabolic Agents