Hematocrit and mean arterial blood pressure in pre- and postmenopause women.
The relationship between mean arterial blood pressure (MAP) and hematocrit (Hct) was studied in pre- and postmenopause women in the city of Durango, Mexico. Premenopause women show a negative trend between parameters that is not statistically significant. MAP and Hct are directly related in postmenopause women (p < 0.01). It is proposed that that this MAP/Hct relationship is in part due to differences in endothelial function where menopause decreases the capacity of the endothelium to respond to increased blood viscosity and shears stress, leading to the increased production of vasodilator mediators to compensate for changes in blood viscosity due to changes in Hct. Comparison with a large group of postmenopause women in the city of Stockholm showed identical trends.
Vázquez
Beatriz Y Salazar
BY
Department of Bioengineering, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92037-0412, USA. borrego209@hotmail.com
Vázquez
Miguel A Salazar
MA
Intaglietta
Marcos
M
de Faire
Ulf
U
Fagrell
Bengt
B
Cabrales
Pedro
P
D001794:Blood Pressure / Q000502:physiology*; D001809:Blood Viscosity / Q000502:physiology; D005260:Female; D006400:Hematocrit; D006801:Humans; D008800:Mexico; D017698:Postmenopause / Q000097:blood / Q000502:physiology; D017697:Premenopause / Q000097:blood / Q000502:physiology; D013548:Sweden