The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry.
In Austria, registration of malignant brain tumours is legally mandatory, whereas benign and borderline tumours are not reported. The Austrian Brain Tumour Registry (ABTR) was initiated under the auspices of the Austrian Society of Neuropathology for the registration of malignant and non-malignant brain tumours. All Austrian neuropathology units involved in brain tumour diagnostics contribute data on primary brain tumours. Non-microscopically verified cases are added by the Austrian National Cancer Registry to ensure a population-based dataset. In 2005, we registered a total of 1,688 newly diagnosed primary brain tumours in a population of 8.2 million inhabitants with an overall age-adjusted incidence rate of 18.1/100,000 person-years. Non-malignant cases constituted 866 cases (51.3%). The incidence rate was higher in females (18.6/100,000) as compared to males (17.8/100,000), while 95/1,688 (5.6%) cases were diagnosed in children (<18 years). The most common histology was meningioma (n = 504, 29.9%) followed by glioblastoma (n = 340, 20.1%) and pituitary adenoma (n = 151, 8.9%). Comparison with the Central Brain Tumor Registry of the United States (CBTRUS) database showed high congruency of findings. The ABTR model led by neuropathologists in collaboration with epidemiologists and the Austrian National Cancer Registry presents a cooperative way to establish a population-based brain tumour registry with high quality data. This setting links cancer registration to the mission of medical practice and research as defined by the World Medical Association in the Declaration of Helsinki. The continued operation of ABTR will aid in monitoring changes in incidence and in identifying regional disease clusters or geographic variations in brain tumour morbidity/mortality.
Wöhrer
Adelheid
A
Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.|Austrian Society of Neuropathology, Austria, Austria.
Waldhör
Thomas
T
Center of Public Health, Department of Epidemiology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Heinzl
Harald
H
Core Unit for Medical Statistics and Informatics, Section of Clinical Biometrics, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Hackl
Monika
M
Austrian National Cancer Registry, Statistics Austria, Guglgasse 13, 1110, Vienna, Austria.
Feichtinger
Johann
J
Department of Pathology, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030, Vienna, Austria.
Gruber-Mösenbacher
Ulrike
U
Department of Pathology, Feldkirch State Hospital, Carinagasse 47, 6807, Feldkirch, Austria.
Kiefer
Andreas
A
Institute of Pathology, State Hospital Klagenfurt, St. Veiter Strasse 47, 9020, Klagenfurt, Austria.
Maier
Hans
H
Department of Pathology, Medical University of Innsbruck, Christoph-Probst-Platz Innrain 52, 6020, Innsbruck, Austria.
Motz
Reinhard
R
Department of Pathology and Neuropathology, State Neuropsychiatric Hospital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020, Linz, Austria.
Reiner-Concin
Angelika
A
Institute of Pathology, Danube Hospital, Langobardenstrasse 122, 1220, Vienna, Austria.
Richling
Bernd
B
Department of Neurosurgery, Christian Doppler Clinic, Paracelsus Private Medical University, Strubergasse 21, 5020, Salzburg, Austria.
Idriceanu
Carmen
C
Department of Neurology, Christian Doppler Clinic, Paracelsus Private Medical University, Strubergasse 21, 5020, Salzburg, Austria.
Scarpatetti
Michael
M
Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036, Graz, Austria.
Sedivy
Roland
R
Department of Clinical Pathology, General Hospital St. Pölten, Probst-Führer-Strasse 4, 3100, St. Pölten, Austria.
Bankl
Hans-Christian
HC
Department of Clinical Pathology, General Hospital St. Pölten, Probst-Führer-Strasse 4, 3100, St. Pölten, Austria.
Stiglbauer
Wolfgang
W
Institute of Pathology, General Hospital Wiener Neustadt, Corvinusring 3-5, 2700, Wiener Neustadt, Austria.
Preusser
Matthias
M
Department of Internal Medicine I, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Rössler
Karl
K
Task Force for Neurosurgical Oncology, Austrian Society of Neurosurgery, Austria.
Hainfellner
Johannes Andreas
JA
Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. johannes.hainfellner@meduniwien.ac.at.|Austrian Society of Neuropathology, Austria, Austria. johannes.hainfellner@meduniwien.ac.at.
D000236:Adenoma / Q000453:epidemiology / Q000473:pathology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria / Q000453:epidemiology; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004806:Ependymoma / Q000453:epidemiology / Q000473:pathology; D005260:Female; D040362:Geographic Information Systems; D005909:Glioblastoma / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D015994:Incidence; D008297:Male; D008577:Meningeal Neoplasms / Q000453:epidemiology / Q000473:pathology; D008875:Middle Aged; D009837:Oligodendroglioma / Q000453:epidemiology / Q000473:pathology; D012042:Registries / Q000592:standards* / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D017678:Sex Distribution; D055815:Young Adult