Age-dependent seroprevalence of Toscana virus in central Italy and correlation with the clinical profile.
In order to estimate the antibody prevalence rates for Toscana virus (TOSV) among children and adults, we evaluated the seroprevalence of TOSV in a population (n = 2,737) living in Tuscany during the period of 1999 to 2006. The seroprevalence rate was 19.8% in adults and 5.8% in children, showing an age-dependent increase in TOSV-specific immunity. Meningitis due to TOSV infection was more frequent in adults than in children.
Terrosi
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C
Department of Molecular Biology, Microbiology Section, University of Siena, Siena, Italy.
Olivieri
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R
Bianco
C
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Cellesi
C
C
Cusi
M G
MG
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood*; D002044:Bunyaviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008581:Meningitis / Q000453:epidemiology; D008875:Middle Aged; D029301:Sandfly fever Naples virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D055815:Young Adult
D000914:Antibodies, Viral