title: Enantioselective Rh-catalyzed hydrogenation of 3-aryl-2-phosphonomethylpropenoates by a new class of chiral ferrocenyl diphosphine ligands.
abstract: A new class of chiral ferrocenyl diphosphine ligands with an imidazole ring, (R(c),S(Fc))-ImiFerroPhos, has been prepared from acylferrocenes through a five-step transformation and successfully applied in the Rh-catalyzed asymmetric hydrogenation of various 3-aryl-substituted 2-phosphonomethylpropenoates, in which a series of chiral 3-phosphono-2-arylmethylpropanoic acid derivatives were achieved in ee values of up to 98%.
authors: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors: Dao-Yong
authors: DY
authors: Wang
authors: Xiang-Ping
authors: XP
authors: Hu
authors: Chuan-Jin
authors: CJ
authors: Hou
authors: Jun
authors: J
authors: Deng
authors: Sai-Bo
authors: SB
authors: Yu
authors: Zheng-Chao
authors: ZC
authors: Duan
authors: Jia-Di
authors: JD
authors: Huang
authors: Zhuo
authors: Z
authors: Zheng
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006865:Hydrogenation; D007093:Imidazoles / Q000737:chemistry*; D008024:Ligands; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007093:Imidazoles; D008024:Ligands; D063065:Organophosphonates; D012238:Rhodium