title: Multidisciplinary management of primary tumors of the vertebral column.
abstract: Primary spinal neoplasms are rare tumors that can lead to significant morbidity secondary to local bone destruction and invasion into adjacent neurological and vascular structures. These tumors represent a clinical challenge to even the most experienced physicians and require a multidisciplinary approach to ensure optimal patient outcomes. This review will discuss the most common primary bone tumors and focus on recent surgical, medical, and radiation treatment advances.
authors: Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. weshsu@jhmi.edu
authors: Wesley
authors: W
authors: Hsu
authors: Thomas A
authors: TA
authors: Kosztowski
authors: Hasan A
authors: HA
authors: Zaidi
authors: Michael
authors: M
authors: Dorsi
authors: Ziya L
authors: ZL
authors: Gokaslan
authors: Jean-Paul
authors: JP
authors: Wolinsky
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017824:Bone Cysts, Aneurysmal / Q000628:therapy; D002648:Child; D002817:Chordoma / Q000601:surgery; D003131:Combined Modality Therapy; D019468:Disease Management; D004621:Embolization, Therapeutic; D005870:Giant Cell Tumors / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy; D006391:Hemangioma / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D033183:Interdisciplinary Communication; D008875:Middle Aged; D018213:Neoplasms, Bone Tissue / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D054219:Neoplasms, Plasma Cell / Q000188:drug therapy / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D055815:Young Adult