title: The azido acid approach to beta-peptides: parallel synthesis of a tri-beta-peptide library by fluorous tagging.
abstract: A small tri-beta-peptide library was prepared starting from three enantio- and diastereopure azido acids. Fluorous tagging followed by two cycles of azide reduction, fluorous solid phase extraction (f-SPE), peptide coupling with the original azido acids and f-SPE provided 27 protected azido peptides. Reduction and HPLC purification provided 25 of the 27 targeted tri-beta-peptides in acceptable yields and excellent purities.
authors: Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 USA.
authors: Xiao
authors: X
authors: Wang
authors: Scott G
authors: SG
authors: Nelson
authors: Dennis P
authors: DP
authors: Curran