title: First successful antegrade single-balloon enteroscopy in a 3-year-old with occult GI bleeding.
abstract: BACKGROUND
  Balloon enteroscopy is an emerging technique to allow access to the small intestine for both diagnostic and therapeutic purposes. To date, there have been few published data documenting the safety and efficacy of balloon enteroscopy in small children.
  
  
  OBJECTIVE
  To describe our experience with single-balloon enteroscopy (SBE) in a 37-month-old toddler with occult GI bleeding.
  
  
  METHODS
  A single case report.
  
  
  METHODS
  A free-standing, academic children's hospital in Denver, Colorado.
  
  
  METHODS
  The patient was a 37-month-old, 13.5-kg toddler with persistent heme-positive stools, severe microcytic anemia, and hypoalbuminemia. Previous workup was significant for eosinophilic inflammation in the antrum and a video capsule study showing erythematous lesions in the small bowel.
  
  
  METHODS
  An antegrade SBE was performed with the child under general endotracheal anesthesia, with biopsy specimens obtained from identified lesions in the jejunum and ileum.
  
  
  METHODS
  Complications and successful treatment of symptoms were the primary endpoints.
  
  
  RESULTS
  The procedure was performed successfully in 85 minutes, passing an estimated 200 cm beyond the pylorus, without complications. Identification of the lesions as consistent with eosinophilic enteropathy led to successful treatment with an elimination diet and corticosteroids.
  
  
  CONCLUSIONS
  The primary limitation of this study is that it is a single case report. Therefore, it is difficult to make a generalized statement regarding the safety and efficacy of balloon enteroscopy in toddlers of this size.
  
  
  CONCLUSIONS
  Antegrade SBE can be a well-tolerated and effective procedure to evaluate occult GI bleeding in children as young as 3 years of age. Further study is needed to better establish safety parameters for balloon enteroscopy in small pediatric patients.
authors: Section of Pediatric Gastroenterology, Hepatology, and Nutrition, The Children's Hospital/University of Colorado Denver, Denver, Colorado, USA.
authors: Robert E
authors: RE
authors: Kramer
authors: David E
authors: DE
authors: Brumbaugh
authors: Jason S
authors: JS
authors: Soden
authors: Kelley E
authors: KE
authors: Capocelli
authors: Edward J
authors: EJ
authors: Hoffenberg
mesh_terms: D053704:Capsule Endoscopy / Q000379:methods*; D002675:Child, Preschool; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D007579:Jejunal Diseases / Q000175:diagnosis / Q000628:therapy*; D011239:Prednisolone / Q000627:therapeutic use; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D011239:Prednisolone