title: Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses.
abstract: We measured T-cell responses to human immunodeficiency virus type 1 (HIV-1) cryptic epitopes encoded by regions of the viral genome not normally translated into viral proteins. T-cell responses to cryptic epitopes and to regions normally spliced out of the HIV-1 viral proteins Rev and Tat were detected in HIV-1-infected subjects.
authors: Division of Experimental Medicine, Department of Medicine, UCSF, San Francisco, California 94110, USA.
authors: Keith E
authors: KE
authors: Garrison
authors: Stephane
authors: S
authors: Champiat
authors: Vanessa A
authors: VA
authors: York
authors: Ashish T
authors: AT
authors: Agrawal
authors: Esper G
authors: EG
authors: Kallas
authors: Jeffrey N
authors: JN
authors: Martin
authors: Frederick M
authors: FM
authors: Hecht
authors: Steven G
authors: SG
authors: Deeks
authors: Douglas F
authors: DF
authors: Nixon
mesh_terms: D018984:Epitopes, T-Lymphocyte / Q000276:immunology*; D015658:HIV Infections / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology* / Q000502:physiology; D006801:Humans; D014176:Protein Biosynthesis; D013601:T-Lymphocytes / Q000276:immunology*; D014779:Virus Replication; D054321:rev Gene Products, Human Immunodeficiency Virus / Q000276:immunology; D054322:tat Gene Products, Human Immunodeficiency Virus / Q000276:immunology
chemical_list: D018984:Epitopes, T-Lymphocyte; D054321:rev Gene Products, Human Immunodeficiency Virus; D054322:tat Gene Products, Human Immunodeficiency Virus