title: Resolving single cone inputs to visual receptive fields.
abstract: With the current techniques available for mapping receptive fields, it is impossible to resolve the contribution of single cone photoreceptors to the response of central visual neurons. Using adaptive optics to correct for ocular aberrations, we delivered micron-scale spots of light to the receptive field centers of neurons in the macaque lateral geniculate nucleus. Parvocellular LGN neurons mapped in this manner responded with high reliability to stimulation of single cones.
authors: Beckman Vision Center, University of California, San Francisco, San Francisco, California, USA. sincichl@vision.ucsf.edu
authors: Lawrence C
authors: LC
authors: Sincich
authors: Yuhua
authors: Y
authors: Zhang
authors: Pavan
authors: P
authors: Tiruveedhula
authors: Jonathan C
authors: JC
authors: Horton
authors: Austin
authors: A
authors: Roorda
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001931:Brain Mapping / Q000379:methods; D055253:Color Vision / Q000502:physiology; D004594:Electrophysiology / Q000295:instrumentation / Q000379:methods; D005829:Geniculate Bodies / Q000166:cytology / Q000502:physiology*; D007834:Lasers; D008297:Male; D009474:Neurons / Q000502:physiology*; D055095:Optics and Photonics / Q000379:methods; D010775:Photic Stimulation / Q000379:methods; D017949:Retinal Cone Photoreceptor Cells / Q000166:cytology / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000166:cytology / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology; D014785:Vision, Ocular / Q000502:physiology; D014794:Visual Fields / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*