Pluripotent stem cell-derived gametes: truth and (potential) consequences.
An emerging body of data suggests that pluripotent stem cells may be able to differentiate to form eggs and sperm. We discuss the state of the science and the potential social implications and offer recommendations for addressing some of the ethical and policy issues that would be raised by the availability of stem cell-derived gametes.
Mathews
Debra J H
DJ
Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD 21205, USA. dmathews@jhmi.edu
Donovan
Peter J
PJ
Harris
John
J
Lovell-Badge
Robin
R
Savulescu
Julian
J
Faden
Ruth
R
D026688:Bioethical Issues; D035843:Biomedical Research / Q000941:ethics; D033041:Embryo Research / Q000941:ethics*; D036281:Genetic Research / Q000941:ethics; D005854:Germ Cells / Q000166:cytology*; D006801:Humans; D007246:Infertility / Q000628:therapy; D039904:Pluripotent Stem Cells / Q000166:cytology*; D011640:Public Policy; D027724:Reproductive Techniques, Assisted / Q000941:ethics