Colorectal cancer screening with CT colonography: key concepts regarding polyp prevalence, size, histology, morphology, and natural history.
OBJECTIVE
The purpose of this article is to provide a timely update on a variety of key polyp topics to construct a proper framework for physicians who are interested in providing CT colonography screening as a clinical service.


CONCLUSIONS
As the medical community considers the expansion of CT colonography for screening, we believe it is prudent to update and review several key concepts regarding colorectal polyps. In particular, it is important to replace the older literature derived from high-risk and symptomatic cohorts with the wealth of newer and more applicable data from average-risk and asymptomatic screening cohorts. Familiarity with current concepts regarding flat (nonpolypoid) lesions and the natural history of small colorectal polyps is also vital to the effective application of this technique.
Pickhardt
Perry J
PJ
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave., Madison, WI 53792-3252, USA. pj.pickhardt@hosp.wisc.edu
Kim
David H
DH
D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic / Q000379:methods*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity