[Dedifferentiation of mammalian neural cells and its induction].
Dedifferentiation of cells has elicited a great deal of attention in the field of cell biology. A great quantity of studies have proved that many types of cells, such as neuron, Schwann cell, astrocyte, oligodendrocyte, etc., within mammalian nervous system could dedifferentiate in different extent, featured in cell becoming immature, reentering cell cycle and regaining pluripotential. This review concerns on dedifferentiation of various types of cells within mammalian nervous system and inducing conditions, as well as its effect on neural regeneration.
Xie
Jia-Xin
JX
Department of Anatomy, the Second Military Medical University, Shanghai 200433, China.
Xu
Jia-Jun
JJ
D000818:Animals; D001253:Astrocytes / Q000166:cytology; D054337:Cell Dedifferentiation; D002454:Cell Differentiation; D008322:Mammals; D009416:Nerve Regeneration; D009474:Neurons / Q000166:cytology*; D012583:Schwann Cells / Q000166:cytology