Electrochemical selectivity enhancement by using monosuccinyl beta-cyclodextrin as a dopant for multi-wall carbon nanotube-modified glassy carbon electrode in simultaneous determination of quercetin and rutin.
Monosuccinyl beta-cyclodextrin (succinyl-beta-CD) was synthesized and the selectivity to quercetin and rutin of the succinyl-beta-CD-modified, multi-wall carbon nanotube (MWNT)-coated, glassy carbon electrode [(succinyl-beta-CD + MWNT)/GCE] was investigated. (1)H NMR and MALDI-MS data confirmed molecular structure of the synthesized succinyl-beta-CD. As a dopant in carboxylated MWNT-modified electrode, succinyl-beta-CD clearly separated the peak potential (E(p)) of quercetin from that of rutin. The measured peak potential separation (DeltaE(p)) was 110 mV. More favorable complexation between succinyl-beta-CD and quercetin may enhance relative selectivity to quercetin of the (succinyl-beta-CD + MWNT)/GCE in quercetin-rutin mixture as compared to the beta-CD-modified GCE.
Jin
Joon-Hyung
JH
Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, 143-701, Republic of Korea.
Kim
Hyunmyung
H
Jung
Seunho
S
D002244:Carbon / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005898:Glass / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011794:Quercetin / Q000032:analysis* / Q000737:chemistry; D012431:Rutin / Q000032:analysis* / Q000737:chemistry; D013057:Spectrum Analysis; D047392:beta-Cyclodextrins / Q000737:chemistry*
D037742:Nanotubes, Carbon; D047392:beta-Cyclodextrins; C545277:monosuccinyl-beta-cyclodextrin; D012431:Rutin; D002244:Carbon; D011794:Quercetin