title: Pediatric HIV: new opportunities to treat children.
abstract: BACKGROUND
  Treating HIV-infected children remains a challenge due to a lack of treatment options, appropriate drug formulations and, in countries with limited resources, insufficient access to diagnostic tests and treatment.
  
  
  OBJECTIVE
  To summarize current data concerning new opportunities to improve the treatment of HIV-infected children.
  
  
  METHODS
  This review includes data from the most recently published peer-reviewed publications, guidelines or presentations at international meetings concerning new ways to treat HIV-infected children.
  
  
  CONCLUSIONS
  New WHO guidelines recommend starting combination antiretroviral treatment in all infants aged < 1 year. Although this is common practice in some high-income countries, implementation of these recommendations in countries with limited resources is still a challenge. There is still an important gap between the availability of licensed drugs in children compared with adults. There remains a need for further pharmacokinetic studies, and for more pediatric formulations of antiretroviral drugs with improved palatability.
authors: Cliniques Universitaires UCL St Luc, Pediatrics Department, 10 Avenue Hippocrate, 1200 Brussels, Belgium. dimitri.vanderlinden@uclouvain.be
authors: Dimitri
authors: D
authors: Van der Linden
authors: Steven
authors: S
authors: Callens
authors: Bénédicte
authors: B
authors: Brichard
authors: Robert
authors: R
authors: Colebunders
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000600:supply & distribution / Q000627:therapeutic use*; D002648:Child; D003906:Developing Countries; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D055118:Medication Adherence; D017410:Practice Guidelines as Topic; D013649:Taste; D014944:World Health Organization
chemical_list: D019380:Anti-HIV Agents