title: Olfactory identification in non-demented elderly population and in mild cognitive impairment: a comparison of performance in clinical odor identification versus Boston Naming Test.
abstract: Performance in olfactory identification was studied in mild cognitive impairment (MCI), using slightly expanded standard clinical approach to study the olfactory nerve. Four hundred and eighty-six cognitively normal individuals and 72 individuals with MCI underwent spontaneous and cued odor identification and delayed odor recall. Performance in these was compared with the performance in the CERAD version of the Boston Naming Test (BNT). The individuals with MCI scores significantly worse in all tests compared with controls, but the performance in tests assessing odor were less impaired than performance in the BNT. Standard assessment of olfactory nerve function is not sufficient to study cognitive impairment in MCI.
authors: Department of Neurology, Kuopio University Hospital, Bldg. 5, P. O. Box 1777, Kuopio 70211, Finland. mikko.laakso@uku.fi
authors: Mikko P
authors: MP
authors: Laakso
authors: Susanna
authors: S
authors: Tervo
authors: Tuomo
authors: T
authors: Hänninen
authors: Matti
authors: M
authors: Vanhanen
authors: Merja
authors: M
authors: Hallikainen
authors: Hilkka
authors: H
authors: Soininen
mesh_terms: D017677:Age Distribution; D000368:Aged; D000375:Aging / Q000502:physiology* / Q000523:psychology; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D015331:Cohort Studies; D015897:Comorbidity; D003463:Cues; D003937:Diagnosis, Differential; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D000857:Olfaction Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D009832:Olfactory Nerve / Q000502:physiology; D011237:Predictive Value of Tests; D015995:Prevalence; D021641:Recognition, Psychology / Q000502:physiology; D012680:Sensitivity and Specificity; D012903:Smell / Q000502:physiology*