title: The association of pagophagia with Helicobacter pylori infection in patients with iron-deficiency anemia.
abstract: This study aimed to determine the relationship between pagophagia (compulsive ice eating) and H. pylori infection in patients with iron-deficiency anemia. We identified H. pylori infection using the (13)C-urea breath test in 45 patients with iron-deficiency anemia (group 1) and 55 patients with iron-deficiency anemia and pagophagia (group 2). Subgroups for testing oral intestinal iron absorption were randomly assigned from both groups. These subgroups consisted of (a) 10 patients with iron-deficiency anemia, (b) 10 patients with iron-deficiency anemia and pagophagia, (c) 10 patients with iron-deficiency anemia, pagophagia, and H. pylori infection before the eradication of H. pylori and (d) subgroup c after eradication therapy. There was no difference in the rate of H. pylori infection in the iron-deficiency anemia groups, with or without pagophagia. Furthermore, oral intestinal iron absorption was not influenced by pagophagia and/or H. pylori infection. Pagophagia did not increase the risk of H. pylori infection in patients with iron-deficiency anemia. Pagophagia and H. pylori infection do not synergistically affect the development of intestinal iron absorption abnormalities.
authors: Department of Family Medicine, Baskent University Faculty of Medicine, 06490, Ankara, Turkey.
authors: Suheyl
authors: S
authors: Asma
authors: Department of Hematology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey. drcanboga@hotmail.com.|Department of Hematology, Baskent University Adana Teaching and Medical Research Center, Dadaloglu Mahallesi Serin Evler Sokak 39 No: 6 Yuregir, 01250, Adana, Turkey. drcanboga@hotmail.com.
authors: Can
authors: C
authors: Boga
authors: Department of Hematology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey.
authors: Hakan
authors: H
authors: Ozdogu
authors: Department of Gastroenterology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey.
authors: Ender
authors: E
authors: Serin
mesh_terms: D000328:Adult; D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D001944:Breath Tests; D005260:Female; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D016480:Helicobacter pylori; D006801:Humans; D007053:Ice; D007408:Intestinal Absorption / Q000187:drug effects; D007501:Iron / Q000378:metabolism / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010842:Pica / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism
chemical_list: D007053:Ice; D007501:Iron