Dynamics of a vesicle in general flow.
An approach to quantitatively study vesicle dynamics as well as biologically-related micro-objects in a fluid flow, which is based on the combination of a dynamical trap and a control parameter, the ratio of the vorticity to the strain rate, is suggested. The flow is continuously varied between rotational, shearing, and elongational in a microfluidic 4-roll mill device, the dynamical trap, that allows scanning of the entire phase diagram of motions, i.e., tank-treading (TT), tumbling (TU), and trembling (TR), using a single vesicle even at lambda = eta(in)/eta(out) = 1, where eta(in) and eta(out) are the viscosities of the inner and outer fluids. This cannot be achieved in pure shear flow, where the transition between TT and either TU or TR is attained only at lambda>1. As a result, it is found that the vesicle dynamical states in a general are presented by the phase diagram in a space of only 2 dimensionless control parameters. The findings are in semiquantitative accord with the recent theory made for a quasi-spherical vesicle, although vesicles with large deviations from spherical shape were studied experimentally. The physics of TR is also uncovered.
Deschamps
J
J
Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel.
Kantsler
V
V
Segre
E
E
Steinberg
V
V
D022162:Cytoplasmic Vesicles / Q000502:physiology*; D008566:Membranes / Q000502:physiology*; D008954:Models, Biological; D012212:Rheology; D014783:Viscosity