Diabetes: Does screening for inducible ischemia improve outcomes?
The DIAD trial investigators have demonstrated that screening for inducible myocardial ischemia did not improve overall clinical outcome in a contemporary cohort of patients with asymptomatic type 2 diabetes, most of whom were receiving excellent medical management and few of whom underwent revascularization. Future studies should be designed to evaluate the clinical value and cost effectiveness of unconditional treatment versus screening using techniques to detect atherosclerotic and ischemic burden, coupled with therapeutic interventions, risk-factor management, and selective use of revascularization in high-risk patients.
Shah
Prediman K
PK
D000241:Adenosine; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D055414:Myocardial Perfusion Imaging; D011237:Predictive Value of Tests; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
D000241:Adenosine