Fewer medications for in vitro fertilization can be better: thinking outside the box.
Minimal stimulation or mild stimulation protocols for in vitro fertilization offer many advantages for all patients, but especially for low and high responders. In the current practice of reducing the number of embryos transferred to a maximum of two for a significant number of patients, using aggressive and high-dose gonadotropins to obtain a large, and sometimes excessive, number of oocytes should be questioned.
Muasher
Suheil J
SJ
Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: muashersj@mcfivf.com.
Garcia
Jairo E
JE
Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
D002985:Clinical Protocols; D003210:Concept Formation; D004305:Dose-Response Relationship, Drug; D005260:Female; D005299:Fertility Agents / Q000008:administration & dosage* / Q000009:adverse effects; D005307:Fertilization in Vitro / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D054315:Oocyte Retrieval / Q000706:statistics & numerical data; D010062:Ovulation Induction / Q000009:adverse effects / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D013850:Thinking; D016896:Treatment Outcome
D005299:Fertility Agents