title: [Effect of Ning Wei Kang Recipe extract on gastrointestinal motor function].
abstract: OBJECTIVE
  To study the effect of Ning Wei Kang Recipe extract on gastrointestinal motor function.
  
  
  METHODS
  The effects of Ning Wei Kang Recipe extract on gastrointestinal motor function were studied in mice, rabbits, and isolated mesenterial intestines of guinea pig according to its effect on acetylcholine or barium chloride-induced contraction.
  
  
  RESULTS
  Ning Wei Kang Recipe extract could significantly decrease the propellent movement of medicine charcoal in the mesenterial intestine of mice (P < 0.01), inhibit the range and speed of mesenterial intestine of rabbits (P < 0.05, or P < 0.01), relax the contration of isolated mesenterial intestines of guinea pig induced by BaCl2 (P < 0.05). But it could not decrease the contration of isolated mesenterial intestines of guinea pig induced by acetylcholine (P< 0.05).
  
  
  CONCLUSIONS
  Ning Wei Kang Recipe extract can significantly inhibit the gastrointestinal motor function. It may be related to blocking positive ion-Ba2+ into gastrointestinal smooth muscle cell.
authors: Department of Pharmacy, Baiyun Hospital, Guangzhou 510500, China.
authors: Yong-Mei
authors: YM
authors: Huang
authors: Jing-Zan
authors: JZ
authors: Deng
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D017609:Barium Compounds; D002712:Chlorides; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D041981:Gastrointestinal Tract / Q000187:drug effects*; D006168:Guinea Pigs; D007077:Ileal Diseases / Q000139:chemically induced / Q000473:pathology*; D007422:Intestines / Q000187:drug effects; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D011897:Random Allocation; D013035:Spasm / Q000139:chemically induced / Q000473:pathology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D017609:Barium Compounds; D002712:Chlorides; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C024986:barium chloride