title: Age-dependent seroprevalence of Toscana virus in central Italy and correlation with the clinical profile.
abstract: In order to estimate the antibody prevalence rates for Toscana virus (TOSV) among children and adults, we evaluated the seroprevalence of TOSV in a population (n = 2,737) living in Tuscany during the period of 1999 to 2006. The seroprevalence rate was 19.8% in adults and 5.8% in children, showing an age-dependent increase in TOSV-specific immunity. Meningitis due to TOSV infection was more frequent in adults than in children.
authors: Department of Molecular Biology, Microbiology Section, University of Siena, Siena, Italy.
authors: C
authors: C
authors: Terrosi
authors: R
authors: R
authors: Olivieri
authors: C
authors: C
authors: Bianco
authors: C
authors: C
authors: Cellesi
authors: M G
authors: MG
authors: Cusi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood*; D002044:Bunyaviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008581:Meningitis / Q000453:epidemiology; D008875:Middle Aged; D029301:Sandfly fever Naples virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral