[Histiocytic sarcoma of the small intestine: Report of one case].
Histiocytic sarcoma (HS) is a rare malignant neoplasm of the lymphohematopoietic system, that occurs in lymph nodes, skin and at extranodal sites, particularly the gastrointestinal tract. Although it shows characteristics histological and immunohistochemical features, it may be misdiagnosed. We report a 67 year-old female patient presenting with colicky abdominal pain and vomiting. A CT scan of the abdomen revealed a tumor in the ileum, that was surgically removed. On pathology, the neoplastic cells displayed large abundant eosinophilic cytoplasm, with bizarre-shaped nuclei, that expressed CD 45, CD 68 and lisozyme. The diagnosis of HS requires the use of a panel of immunohistochemical markers and may be supported by ultrastructural findings.
Avilés-Salas
Alejandro
A
Departamento de Patología, Instituto Nacional de Cancerología, México, D.F. alejandroaviles2001@yahoo.com
Peña-Torres
María de Lourdes
Mde L
Molina-Cruz
Angel
A
Rivas-Vera
Silvia
S
D000368:Aged; D005260:Female; D054747:Histiocytic Sarcoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology* / Q000628:therapy; D008198:Lymph Nodes / Q000473:pathology