title: Effect of acculturation on the acceptability of potential microbicides and sexual risk-taking.
abstract: BACKGROUND
  The objective was to determine the acceptability and use patterns of potential microbicides among African American (AA), acculturated Hispanic (AH), and less acculturated Hispanic (LAH) women. We measured baseline sexual risk-taking and the likelihood of behavioral change, given effective microbicides.
  
  
  METHODS
  Interview of 506 Mexican-American and AA women, all of whom have a sexually transmitted infection enrolled in Project Sexual Awareness for Everyone.
  
  
  RESULTS
  The 3 groups reported similarly high acceptance of potential microbicides (76%-83% P = 0.24). LAHs were most likely to report they would use microbicides covertly (P = 0.03). Given the possibility of effective microbicides, AHs were consistently more likely to report risk disinhibition. AHs, as compared to LAHs and AAs, respectively, were most likely to report that they would not use condoms, (53% vs. 33% vs. 30% P <0.001), would have a 1-night stand (18% vs. 8% vs. 6% P = 0.02), or would have sex with humans before they got to know them (18% vs. 8% vs. 6% P = 0.01). AHs were also most likely to say they would or probably would change from baseline safe sexual practices to unsafe sexual behaviors if potential microbicides were available. Age was controlled for in the analysis as AHs were younger than AAs and LAHs.
  
  
  CONCLUSIONS
  Future microbicides were acceptable among this at risk cohort. Acculturation was a predictor of risk disinhibition and should be considered when tailoring sexually transmitted infection prevention messages, given the advent of effective microbicides.
authors: Department of Obstetrics and Gynecology, University of Texas Health Sciences Center San Antonio, 7703 Floyd Curl Drive, Mail Code 7836, San Antonio, TX 78229-3900, USA. thurmana@uthscsa.edu
authors: Andrea Ries
authors: AR
authors: Thurman
authors: Alan E C
authors: AE
authors: Holden
authors: Rochelle N
authors: RN
authors: Shain
authors: Sondra
authors: S
authors: Perdue
authors: Jeanna M
authors: JM
authors: Piper
mesh_terms: D000069:Acculturation; D000293:Adolescent; D001741:Black or African American; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D015331:Cohort Studies; D006630:Hispanic or Latino; D006801:Humans; D007407:Interviews as Topic; D010349:Patient Compliance; D016032:Randomized Controlled Trials as Topic; D012309:Risk-Taking; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000208:ethnology / Q000517:prevention & control; D013781:Texas / Q000453:epidemiology; D047568:Unsafe Sex; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents