title: Outcome of intralesional curettage for low-grade chondrosarcoma of long bones.
abstract: BACKGROUND
  Different treatment strategies for low-grade chondrosarcomas are reported in the literature with variable outcomes. The aim of this study was to assess the oncological and functional outcomes associated with intralesional curettage and cementation of the lesion as a treatment strategy.
  
  
  METHODS
  We performed a retrospective review of 39 consecutive patients with intramedullary low-grade chondrosarcoma of long bones treated by intralesional curettage and cementation at our institution between 1999 and 2005.
  
  
  RESULTS
  There were 10 males and 29 females with a mean age of 55.5 years (32-82), and a mean follow-up of 5.1 years (3-8.7). Local recurrence occurred in two patients (5%) within the first two years following index surgery. Both were treated by re-curettage and cementation of the resultant defects. A second local recurrence developed a year later in one of these two patients, for which a further curettage followed by local liquid nitrogen treatment was performed. Overall, there were no cases of post-operative complications or metastases. The patients were assessed using the Musculoskeletal Tumour Society scoring system (MSTS) to determine limb function. The average score achieved was 94% (79-100%).
  
  
  CONCLUSIONS
  Intralesional curettage is an effective treatment strategy for low-grade intramedullary chondrosarcoma of long bones, with excellent oncological and functional results. Careful case selection with stringent clinical and radiographic follow-up is recommended.
authors: Department of Orthopaedic Oncology, London Bone and Soft Tissue Sarcoma Service, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, United Kingdom. sammyhanna@hotmail.com
authors: S A
authors: SA
authors: Hanna
authors: P
authors: P
authors: Whittingham-Jones
authors: M D
authors: MD
authors: Sewell
authors: R C
authors: RC
authors: Pollock
authors: J A
authors: JA
authors: Skinner
authors: A
authors: A
authors: Saifuddin
authors: A
authors: A
authors: Flanagan
authors: S R
authors: SR
authors: Cannon
authors: T W R
authors: TW
authors: Briggs
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000601:surgery*; D002813:Chondrosarcoma / Q000601:surgery*; D003475:Curettage / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018365:Neoplasm, Residual; D012189:Retrospective Studies