title: Central sleep apnoea in Rett syndrome.
abstract: Breathing disturbances in Rett syndrome were reported almost entirely during wakefulness, with normal respiration during sleep. We studied a case of a proven MECP2 mutation in a girl, whose videopolygraphic and polysomnographic monitoring suggested the evidence of central apnoeas not only during awake, but also during sleep. Apart from prevalent awake respiratory dysfunction, central apnoeas in Rett syndrome may be also present during sleep.
authors: Epilepsy Center, Neurological Unit, Casa Divina Provvidenza, Opera Don Uva, Via Bovio 78, 70052, Bisceglie (BAT), Italy. giudorsi@yahoo.it
authors: Giuseppe
authors: G
authors: d'Orsi
authors: Vincenzo
authors: V
authors: Demaio
authors: Francesco
authors: F
authors: Scarpelli
authors: Teresa
authors: T
authors: Calvario
authors: Mauro G
authors: MG
authors: Minervini
mesh_terms: D002675:Child, Preschool; D004569:Electroencephalography / Q000379:methods; D004576:Electromyography / Q000379:methods; D005260:Female; D006801:Humans; D015518:Rett Syndrome / Q000150:complications*; D020182:Sleep Apnea, Central / Q000209:etiology*; D014851:Wakefulness / Q000502:physiology