Role of topical peptides in preventing or treating aged skin.
Ageing, a basic biological process seen in all living creatures, is not preventable. Surgical and topical modalities have been invented and substances were applied topically to alter the ageing process. Peptides and proteins, frequently used for this purpose, were categorized into four groups: signal peptides, enzyme-inhibitor peptides, neurotransmitter-inhibitor peptides and carrier peptides. We comprehensively review eligible studies -including controlled ex vivo or in vivo efficacy studies on any topical peptide or protein that has been administered to treat signs and symptoms of ageing.
Gorouhi
F
F
Department of Dermatology, University of California, San Francisco, CA 94143-0989, USA.
Maibach
H I
HI
D000287:Administration, Topical; D003358:Cosmetics / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans; D010455:Peptides / Q000008:administration & dosage* / Q000493:pharmacokinetics; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012869:Skin Absorption; D015595:Skin Aging / Q000187:drug effects*
D003358:Cosmetics; D010455:Peptides