Acute fibrinous and organizing pneumonia following hematopoietic stem cell transplantation.
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls within the alveoli and thickening of the alveolar septum, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). We report the first case of AFOP following allogeneic hematopoietic stem cell transplantation.
Lee
Sang Min
SM
Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Park
Jae-Jung
JJ
Sung
Sun Hee
SH
Kim
Yookyung
Y
Lee
Kyoung Eun
KE
Mun
Yeung-Chul
YC
Lee
Soon Nam
SN
Seong
Chu Myong
CM
D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D018549:Cryptogenic Organizing Pneumonia / Q000209:etiology / Q000473:pathology; D017809:Fatal Outcome; D005938:Glucocorticoids / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000601:surgery*; D008171:Lung Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000209:etiology; D020551:Pulse Therapy, Drug; D013902:Radiography, Thoracic; D012131:Respiratory Insufficiency / Q000209:etiology; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids