Nodular amyloidosis: differentiation from colloid milium by electron microscopy.
Nodular amyloidosis is a primary cutaneous amyloidosis characterized by the deposition of amyloid L-type fibril proteins in the dermis. Clinical history and routine histology may not be sufficient to differentiate nodular amyloidosis from colloid milium. We present a case of a 45-year-old man with nodular amyloidosis, whose diagnosis was confirmed by the characteristic appearance of filaments on electron microscopy.
Lai
Kimberly W
KW
University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. kimberly_lai@urmc.rochester.edu
Lambert
Emily
E
Coleman
Stephen
S
Scott
Glynis
G
Mercurio
Mary Gail
MG
D000152:Acne Vulgaris / Q000150:complications / Q000188:drug therapy; D000686:Amyloidosis / Q000150:complications / Q000473:pathology*; D003879:Dermatologic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005145:Face / Q000473:pathology; D005148:Facial Dermatoses / Q000473:pathology; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use; D008297:Male; D046529:Microscopy, Electron, Transmission; D008875:Middle Aged; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*
D003879:Dermatologic Agents; D015474:Isotretinoin