title: Enantioselective Reduction of Prochiral Ketones using Spiroborate Esters as Catalysts.
abstract: Novel spiroborate esters derived nonracemic 1,2-aminoalcohols and ethylene glycol are reported as highly effective catalysts for the asymmetric borane reduction of a variety of prochiral ketones with borane-dimethyl sulfide complex at room temperature. Optically active alcohols were obtained in excellent chemical yields using 0.1 to 10 mol % of catalysts with up to 99% ee.
authors: Department of Chemistry, University of Puerto Rico - Humacao, CUH Station, Humacao, Puerto Rico 00791, USA.
authors: Viatcheslav
authors: V
authors: Stepanenko
authors: Melvin
authors: M
authors: De Jesus
authors: Wildeliz
authors: W
authors: Correa
authors: Irisbel
authors: I
authors: Guzman
authors: Cindybeth
authors: C
authors: Vazquez
authors: Wilanet
authors: W
authors: de la Cruz
authors: Margarita
authors: M
authors: Ortiz-Marciales
authors: Charles L
authors: CL
authors: Barnes