title: Synergistic effect of air pollution and habitual smoking on the retention of inorganic fibers identified as ferruginous bodies in autopsy cases in Mexico City.
abstract: In order to evaluate the synergistic effect of habitual smoking and air pollution in Mexico City on the retention of inorganic fibers, ferruginous bodies (FB) were quantified as markers of exposure to inorganic fibers in lung digests from 426 autopsy cases. FB were isolated from 426 lung digests from cases with several lung diseases. The results revealed more retention of FB in the smokers group than in non-smokers: 38 FB per gram (FB/g) versus 11.2 FB/g, respectively (p < 0.05). Male smokers living in Mexico City increased their median to 54 FB/g. This contrasts with the median of outside residents: 11.2 FB/g (p < 0.002). Housewives and manual laborers increased their medians when the smoking habit was positive: from 11 to 14 FB/g, and from 16 to 21.5 FB/g, respectively. There is an effect of tobacco smoke on the retention of more fibers identified as FB when the individuals are males and Mexico City residents.
authors: Departamento de Patología, Instituto Nacional de Enfermedades Respiratorias-SS, Calzada de Tlalpan, Mexico.
authors: Margarita
authors: M
authors: Salazar-Flores
authors: Rosa María
authors: RM
authors: Rivera-Rodríguez
authors: María Eugenia
authors: ME
authors: Vázquez-Manriquez
authors: Francisco
authors: F
authors: Arenas-Huertero
mesh_terms: D000328:Adult; D000368:Aged; D000397:Air Pollution / Q000009:adverse effects*; D001344:Autopsy; D005260:Female; D006801:Humans; D007287:Inorganic Chemicals; D008168:Lung / Q000473:pathology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009790:Occupations; D011658:Pulmonary Fibrosis / Q000473:pathology*; D012727:Sex Characteristics; D012907:Smoking / Q000453:epidemiology / Q000473:pathology*; D014505:Urban Population
chemical_list: D007287:Inorganic Chemicals