Adenovirus type 3 outbreak in connecticut associated with a novel variant.
An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died.
Landry
Marie L
ML
Department of Laboratory Medicine, Yale New Haven Hospital, Yale University School of Medicine, Connecticut 06520-8035, USA. marie.landry@yale.edu
Lebeck
Mark G
MG
Capuano
Ana W
AW
McCarthy
Troy
T
Gray
Gregory C
GC
D000257:Adenoviridae Infections / Q000453:epidemiology* / Q000821:virology*; D000260:Adenoviruses, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D003237:Connecticut / Q000453:epidemiology; D016172:DNA Fingerprinting; D004279:DNA, Viral / Q000235:genetics; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D017720:Molecular Epidemiology; D012150:Polymorphism, Restriction Fragment Length; D000091402:Prohibitins
D004279:DNA, Viral; C000717331:PHB2 protein, human; D000091402:Prohibitins