title: [Recombinant activated factor VII and intraoperative use of cell saver in neurosurgical treatment of arteriovenous malformation].
abstract: BACKGROUND
  Arteriovenous (AV) malformation of brain causes abundant intraoperative bleedings, because of increased blood flow, which complicates operative treatment. The use of cell saver for intraoperative salvage of blood and recombinant activated factor VII (rFVIIa) significantly reduces complications during operative treatment.
  
  
  METHODS
  We present a 29-year old male patient with AV malformation of the 4th degree on Spetzler-Martin scale. Because of the possibility of abundant bleeding, a cell saver (Sequestra 1000 Metronic, USA) was used, and to achieve and control adequate haemostasis, we used rFVIIa.
  
  
  CONCLUSIONS
  The use of cell saver for intraoperative blood salvage and rFVIIa proved successful in operative treatment of AV malformation of 4th degree.
authors: Vesna
authors: V
authors: Novak
authors: Budimir
authors: B
authors: Petrović
authors: Branko
authors: B
authors: Calija
authors: Ljiljana
authors: L
authors: Mitov
authors: Zoran
authors: Z
authors: Rancić
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000517:prevention & control; D001804:Blood Transfusion, Autologous; D015942:Factor VIIa / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000601:surgery*; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D006490:Hemostatics; D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa