title: Frequency of norovirus in stool samples from hospitalized children due to acute gastroenteritis in Anatolia, Turkey, 2006-2007.
abstract: Noroviruses are among the most common causes of sporadic enteritis in childhood. In this pilot study, the frequency of norovirus infection in children in mid-western Turkey was investigated from November 2006 to June 2007. Noroviruses were detected in 17% of samples (15/88) by a combination of 2 different RT-PCR assays, both targeting an overlapping region of the RNA-dependent RNA polymerase gene. By sequence analysis, most strains were characterized as GIIb/Hilversum. One strain was characterized as GII.4/2006a, a variant that appeared worldwide in 2006, while another strain was characterized as a rare genotype, GII.6. This study demonstrates the importance of norovirus in paediatric diarrhoea and suggests the heterogeneity of circulating strains in Turkey.
authors: Department of Microbiology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey. maltindis@gmail.com
authors: Mustafa
authors: M
authors: Altindis
authors: Krisztián
authors: K
authors: Bányai
authors: Raike
authors: R
authors: Kalayci
authors: Cihangir
authors: C
authors: Gulamber
authors: Resit
authors: R
authors: Koken
authors: Yasin
authors: Y
authors: Yoldas
authors: Pinar
authors: P
authors: Aykurt
authors: Vito
authors: V
authors: Martella
mesh_terms: D000208:Acute Disease; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D006761:Hospitals; D006801:Humans; D007223:Infant; D029322:Norovirus / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014421:Turkey / Q000453:epidemiology