title: [Effect of growth factors on morphogenesis of human keratinocytes in vitro].
abstract: The effect of some growth factors on morphogenetic processes in the primary culture of human epidermal keratinocytes was studied in the model of formation of tubule-like structures in collagen gel. Culturing of keratinocytes in the presence of IGF and bFGF did not induce growth of tubule-like structures, whereas EGF, KGF, and HGF promoted the growth of three-dimensional epidermal outgrowths whose shape and size varied depending on the growth factor used.
authors: K Iu
authors: KIu
authors: Gnedeva
authors: E S
authors: ES
authors: Chermnykh
authors: E A
authors: EA
authors: Voroteliak
authors: A V
authors: AV
authors: Vasil'ev
authors: V V
authors: VV
authors: Terskikh
mesh_terms: D048430:Cell Shape / Q000187:drug effects*; D048429:Cell Size / Q000187:drug effects*; D002478:Cells, Cultured; D003094:Collagen / Q000378:metabolism; D000078404:Epidermal Cells; D004817:Epidermis / Q000502:physiology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000494:pharmacology*; D015603:Keratinocytes / Q000166:cytology / Q000502:physiology*
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D003094:Collagen