Ocular sarcoidosis in a Korean population.
The aim of current study was to evaluate the incidence and characteristics of ocular sarcoidosis in a Korean population. We conducted a retrospective study of 104 consecutive patients with biopsy-proven sarcoidosis seen at Asan Medical Center in Seoul, Korea, from 1993 to 2007. Medical records, photographs, and fluorescein angiograms were reviewed. Of 104 patients, 22 (21%) had intraocular involvement with female predominance (86%, M:F=3:19). Of the 39 eyes with ocular involvement, 16 (41%) eyes had isolated anterior uveitis, 12 (31%) eyes had intermediate uveitis, 6 eyes (15%) had panuveitis with retinal vasculitis, and 5 (13%) eyes had panuveitis with punched multifocal choroiditis. Mean duration of ophthalmologic follow-up was 62 months. All ocular inflammation was well managed with topical steroid and/or systemic steroid with relatively good final visual outcomes. Ocular complications such as cataract (12 eyes, 30%), glaucoma (6 eyes, 15%), vitreous opacity (1 eye, 3%), cystoid macular edema (3 eyes, 7%), neovascularization (2 eye, 5%), and epiretinal membrane (4 eye, 10%) were related to ocular sarcoidosis. In Korea, where sarcoidosis is very rare, our study indicates relatively low ocular and predominantly non posterior segment involvement with relatively good visual prognosis.
Lee
Sun Young
SY
Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Lee
Hee Gyung
HG
Kim
Dong Soon
DS
Kim
June-Gone
JG
Chung
Hyewon
H
Yoon
Young Hee
YH
D000328:Adult; D000367:Age Factors; D044466:Asian People; D002833:Choroiditis / Q000175:diagnosis; D005128:Eye Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D031300:Retinal Vasculitis / Q000175:diagnosis; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D013256:Steroids / Q000627:therapeutic use; D014606:Uveitis, Anterior / Q000175:diagnosis; D015867:Uveitis, Intermediate / Q000175:diagnosis
D013256:Steroids