Retinally stabilized cone-targeted stimulus delivery.
We demonstrate projection of highly stabilized, aberration-corrected stimuli directly onto the retina by means of real-time retinal image motion signals in combination with high speed modulation of a scanning laser. In three subjects with good fixation stability, stimulus location accuracy averaged 0.26 arcminutes or approximately 1.3 microns, which is smaller than the cone-to-cone spacing at the fovea. We also demonstrate real-time correction for image distortions in adaptive optics scanning laser ophthalmoscope (AOSLO) with an intraframe accuracy of about 7 arcseconds.
Arathorn
David W
DW
Yang
Qiang
Q
Vogel
Curtis R
CR
Zhang
Yuhua
Y
Tiruveedhula
Pavan
P
Roorda
Austin
A