Neuropsychological profile of delusional disorder.
BACKGROUND
Previous studies concerned with neuropsychological aspect of delusions, were mainly focused on specific forms of this disorder, such as Cotard or Capgras type of delusions. Comparatively small numbers of investigations were concerned with cognitive deficiencies accompanying the delusions. The substance of this study includes the detection of neuropsychological dysfunctions in patients with delusional disorder, and tracing of these cognitive distortions to appropriate brain regions.


METHODS
The investigation is designed as a comparative study. Inpatients with delusion are compared with normal subjects from the aspect of the following cognitive functions: attention, memory, visuospatial and visuoconstruction organization, executive ability, verbal divergent thinking.


RESULTS
Attention, memory (verbal modality) and psychomotor skill tasks are most susceptible to delusional effects.


CONCLUSIONS
The neuropsychological profile of patients with delusional disorder includes impediment of complex attention modalities. From this primary disorder, there also stems a disorder of verbal memory in the sense of reduced recognition. These cognitive distortions suggest a dysfunction of the anterior regions of the cerebrum, mainly of the prefrontal and sinistral temporal regions.
Leposavić
Ivana
I
The Institute of Psychiatry, Clinical Centre of Serbia, Pasterova 2, 11000 Belgrade, Serbia. ivana.leposavic@gmail.com
Leposavić
Ljubica
L
Jasović-Gasić
Miroslava
M
D000124:Achievement; D000328:Adult; D001288:Attention; D003702:Delusions / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D009949:Orientation; D010469:Perceptual Distortion; D011340:Problem Solving; D011597:Psychomotor Performance; D021641:Recognition, Psychology; D013850:Thinking; D014706:Verbal Learning