[Cocaine-induced agitated delirium, a different consequence of cocaine addiction].
In the past 10 years, chronic drug abuse health problems have become complex medical-legal problems. These include Cocaine-Induced Agitated Delirium, an idiosyncratic illness appears 1-2 hours after regular drug intake and can cause death without overdose is detected at autopsy. This review studies the molecular changes caused by cocaine abuse that derived into Cocaine-Induced Agitated Delirium. The molecular-clinical correlation links the phenomena induced by the abuse expressed at different levels of complexity, from the biochemical to the social. The purpose here is to induce a greater awareness of this illness to improve its prevention, to obtain its early diagnosis and to achieve its appropriate therapeutic-legal approach. Cocaine-Induced Agitated Delirium should be considered as the result of several unseen changes, that if they reach a critical threshold trigger the fatal outcome. This makes the abuse of cocaine and the individual predisposition solely responsible for its appearance.
Fadel
Daniel
D
Primera Cátedra de Farmacología, Facultad de Medicina, Universidad de Buenos Aires, Argentina. dafadel@gmail.com
Serra
Héctor A
HA
D019970:Cocaine-Related Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D003693:Delirium / Q000209:etiology*; D006801:Humans