title: Reduction by 98% in uterine myoma volume associated with significant symptom relief after peripheral treatment with magnetic resonance imaging-guided focused ultrasound surgery.
abstract: Magnetic resonance imaging-guided focused ultrasound surgery is a noninvasive treatment for symptomatic uterine myomas. Previous studies have demonstrated a correlation between the treated volume of the myoma, improvement in symptoms, and lesion shrinkage. We report a case in which MRgFUS treatment only at the periphery of the myoma resulted in a 98% reduction in tumor volume at 8 months posttreatment, and at 12-month follow-up, only a small lesion was visible at magnetic resonance imaging. The patient's symptoms, as assessed using the Uterine Fibroids Symptom and Quality of life (UFS-QOL) questionnaire, were substantially improved at both 6 and 12 months posttreatment. We also provide a hypothesis to explain this dramatic reduction in myoma volume after only partial MRgFUS treatment of the lesion.
authors: Barra D'Or Hospital, LABS-D'Or Hospital Network, Batafogo, Rio de Janeiro, Brazil. nandachagas@hotmail.com
authors: Fernanda Chagas Monteiro
authors: FC
authors: de Melo
authors: Luana
authors: L
authors: Diacoyannis
authors: André
authors: A
authors: Moll
authors: Fernanda
authors: F
authors: Tovar-Moll
mesh_terms: D000328:Adult; D055356:Endometrial Ablation Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000628:therapy*; D053783:Magnetic Resonance Imaging, Interventional; D014464:Ultrasonic Therapy / Q000379:methods*; D014594:Uterine Neoplasms / Q000628:therapy*