title: Progressive load training for the quadriceps muscle associated with proprioception exercises for the prevention of falls in postmenopausal women with osteoporosis: a randomized controlled trial.
abstract: This study aims to evaluate the effect of 18-week progressive muscular strength and proprioception training program on the muscle strength of the quadriceps, in prevention of falls in postmenopausal women with osteoporosis. The incidence of falls in the intervention group was significantly lower than in the control group (incidence rate ratio (IRR) = 0.263, 95% CI 0.10-0.68).
  
  
  BACKGROUND
  This study aims to evaluate the effect of a progressive muscular strength and proprioception training program on the muscle strength of the quadriceps, balance, quality of life, and reduction in the risk of falls in postmenopausal women with osteoporosis.
  
  
  METHODS
  One hundred sedentary postmenopausal women with osteoporosis, ages ranging from 55 to 75, were selected and randomized into two groups: the intervention group comprised of 50 patients who underwent a 18-week of progressive load training for the quadriceps muscle (50% up to 80% of 1-RM-one maximum repetition) and proprioception training associated to a drug treatment of osteoporosis and the control group that included 50 patients who only underwent a drug treatment of osteoporosis. The muscular strength, balance, functional mobility, and quality of life were evaluated in the beginning and end of the research. The number of falls was evaluated 24 weeks post-treatment.
  
  
  RESULTS
  Eighty-five patients concluded the research. The program promoted a significant difference among the groups for SF-36 in the eight sub-scales (p <or= 0.0018), Timed Up & Go Test (p < 0.0001), 1-RM test (p < 0.0001), Berg Balance Scale (p < 0.0001) and also a decrease in the number of falls in the intervention group compared to control (IRR = 0.263, 95% CI 0.10-0.68, p = 0.0064).
  
  
  CONCLUSIONS
  The association of progressive strength training for the quadriceps and the proprioceptive training is effective for the prevention of falls, increasing the muscle power, the static and dynamic balance and increasing the speed of the motor responses, therefore improving the performance of daily activities.
authors: Discipline of Internal and Therapeutical Medicine and Evidence-Based Medicine, Brazilian Cochrane Centre, Universidade Federal de São Paulo, São Paulo, Brazil. leppteixeira@gmail.com
authors: L E P P
authors: LE
authors: Teixeira
authors: K N G
authors: KN
authors: Silva
authors: A M
authors: AM
authors: Imoto
authors: T J P
authors: TJ
authors: Teixeira
authors: A H
authors: AH
authors: Kayo
authors: R
authors: R
authors: Montenegro-Rodrigues
authors: M S
authors: MS
authors: Peccin
authors: V F M
authors: VF
authors: Trevisani
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control*; D000368:Aged; D015519:Bone Density / Q000502:physiology; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005269:Femur / Q000503:physiopathology; D006801:Humans; D008159:Lumbar Vertebrae / Q000503:physiopathology; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy / Q000503:physiopathology / Q000534:rehabilitation*; D011434:Proprioception / Q000502:physiology*; D052097:Quadriceps Muscle / Q000503:physiopathology*; D011788:Quality of Life; D055070:Resistance Training / Q000379:methods*; D016037:Single-Blind Method
chemical_list: D050071:Bone Density Conservation Agents