[Trabeculotomy on primary congenital glaucoma: a retrospective study of 164 cases (257 eyes)].
OBJECTIVE
To study the relationship of long-term effect of trabeculotomy on primary congenital glaucoma and the related risk factors.


METHODS
164 consecutive patients with primary congenital glaucoma (257 eyes), underwent initial surgery of trabeculotomy between 1996 and 2007. Follow-up was conducted for 30.9 (8.6 - 58.3) months, with a follow-up rate of 89.02%. Multivariate analysis by Logistic regression was conducted to analyze the relation of the factors including age of onset, time between onset and operation, preoperative intraocular pressure, clarity of cornea, and corneal diameter to the failure of surgery. Cox proportional hazards regression modeling was used to analyze the factors related to success of surgery.


RESULTS
Multivariate logistic regression showed that the preoperative intraocular pressure (IOP) and clarity of cornea were independent risk factors for final outcome (OR(IOP) = 1.408, P = 0.047, and OR(CLA) = 1.691, P = 0.019). Cox regression showed that clarity of cornea was the factor related to the surgery success time (OR(CLA) = 1.632, P = 0.008).


CONCLUSIONS
Clarity of cornea reflexes the condition of primary congenital glaucoma more stably than IOP. It is possible to prognosticate the surgical outcome to combine the clarity of cornea with the IOP value before operation.
Chen
Xue-Li
XL
Department of Ophthalmology, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai 200031, China.
Chen
Yu-Hong
YH
Jin
Xiao-Hong
XH
Sun
Xing-Huai
XH
Meng
Fan-Rong
FR
Guo
Wen-Yi
WY
Qian
Shao-Hong
SH
Song
Yue-Lian
YL
Wang
Jia-Jian
JJ
D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000151:congenital* / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015999:Multivariate Analysis; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D014130:Trabeculectomy; D016896:Treatment Outcome