title: Plasmodium falciparum and Plasmodium vivax: so similar, yet very different.
abstract: The recently published whole genome sequence information of one of the human malaria parasites, Plasmodium vivax, have provided opportunities to compare similar features with Plasmodium falciparum that causes the most deadly form of human malaria. We herewith present comparative genomic insights into the whole genome of the two parasites and also to several other characteristics in terms of disease pathogenecity, evolution, etc. We show that while high similarities exist at the functional gene level, several contrasting features for other characteristics are hallmarks of these two human malaria parasites.
authors: Evolutionary Genomics and Bioinformatics Laboratory, National Institute of Malaria Research, Sector 8, Dwarka, New Delhi 110 077, India. aparup@mrcindia.org
authors: Aparup
authors: A
authors: Das
authors: Meenu
authors: M
authors: Sharma
authors: Bhavna
authors: B
authors: Gupta
authors: Aditya Prasad
authors: AP
authors: Dash
mesh_terms: D000818:Animals; D017125:Genes, Protozoan; D018503:Genome, Protozoan; D006801:Humans; D008288:Malaria / Q000469:parasitology; D010963:Plasmodium falciparum / Q000235:genetics* / Q000472:pathogenicity; D010966:Plasmodium vivax / Q000235:genetics* / Q000472:pathogenicity; D037521:Virulence Factors / Q000235:genetics*
chemical_list: D037521:Virulence Factors