title: Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population.
abstract: This study evaluated the clinical and histopathologic aspects of 41 cases of oral lipomas diagnosed in a Brazilian population. All records from patients diagnosed with oral lipoma between 1970 and 2008 were reviewed. Histological sections were evaluated by light microscopy. There was a predominance of females (2.4:1), with a peak incidence between the sixth and seventh decade. The buccal mucosa was the most affected site (53.7%), followed by the buccal sulcus (14.6%) and tongue (9.8%). Tumor size ranged from 0.5 to 10 cm and the mean reported duration was 48 months. Histologically, the following variants were identified: lipoma (41.5%), fibrolipoma (34.1%), spindle cell lipoma (9.8%), sialolipoma (9.8%), osteolipoma (2.4%), and chondrolipoma (2.4%). Most tumors were well delimited, irrespective of the variant. Lipomas are rare tumors of the oral cavity. The characterization of new variants, such as sialolipomas, and the identification of histological subtypes in already known variants, such as low-fat and fat-free spindle cell lipomas, highlight the importance for careful microscopic evaluation of these tumors, which might be combined with immunohistochemistry in some cases.
authors: School of Dentistry, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
authors: Luiz Eduardo Rodrigues
authors: LE
authors: Juliasse
authors: Cassiano Francisco Weege
authors: CF
authors: Nonaka
authors: Leão Pereira
authors: LP
authors: Pinto
authors: Roseana de Almeida
authors: Rde A
authors: Freitas
authors: Márcia Cristina da Costa
authors: MC
authors: Miguel
mesh_terms: D017667:Adipocytes / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D001938:Brazil; D003238:Connective Tissue / Q000473:pathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008067:Lipoma / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology; D012189:Retrospective Studies; D055815:Young Adult