title: Comparison of clinical and radiographic characteristics between nodular bronchiectatic form of nontuberculous mycobacterial lung disease and diffuse panbronchiolitis.
abstract: The nodular bronchiectatic form of nontuberculous mycobacterial (NTM) lung disease and diffuse panbronchiolits (DPB) show similar clinical and radiographic findings. The present study was performed to clarify the clinicoradiographic similarities as well as the differences between NTM lung disease and DPB. The initial clinicoradiographic features of 78 patients with the nodular bronchiectatic form of NTM lung disease (41 patients with Mycobacterium avium complex infection and 37 patients with Mycobacterium abscessus infection) were compared with those of 35 patients with DPB. Old age, female sex, a history of tuberculosis treatment, and hemoptysis were related to NTM lung disease while exertional dyspnea, coarse crackles, history of sinusitis, obstructive abnormalities in pulmonary function tests, and hypoxemia were related to DPB. The number of lobes involved with bronchiolitis and bronchiectasis on chest computed tomography were more numerous in DPB patients. There is considerable overlap in the clinical and radiographic appearances of the nodular bronchiectatic form of NTM lung disease and DPB, although some clinicoradiographic features differ between two diseases. The correct diagnosis, including aggressive microbiologic evaluation, should be made for the appropriate management of patients presenting with bilateral bronchiectasis and bronchiolitis.
authors: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Hye Yun
authors: HY
authors: Park
authors: Gee Young
authors: GY
authors: Suh
authors: Man Pyo
authors: MP
authors: Chung
authors: Hojoong
authors: H
authors: Kim
authors: O Jung
authors: OJ
authors: Kwon
authors: Myung Jin
authors: MJ
authors: Chung
authors: Tae Sung
authors: TS
authors: Kim
authors: Kyung Soo
authors: KS
authors: Lee
authors: Won-Jung
authors: WJ
authors: Koh
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001987:Bronchiectasis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D001988:Bronchiolitis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D015269:Mycobacterium avium Complex; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000000981:diagnostic imaging; D012129:Respiratory Function Tests; D012737:Sex Factors; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000628:therapy