High-resolution OCT balloon imaging catheter with astigmatism correction.
We report new optics designs for an optical coherence tomography (OCT) balloon imaging catheter to achieve diffraction-limited high resolution at a large working distance and enable the correction of severe astigmatism in the catheter. The designs employed a 1 mm diameter gradient-index lens of a properly chosen pitch number and a glass rod spacer to fully utilize the available NA of the miniature optics. Astigmatism caused by the balloon tubing was analyzed, and a method based on a cylindrical reflector was proposed and demonstrated to compensate the astigmatism. A catheter based on the new designs was successfully developed with a measured diffraction-limited lateral resolution of approximately 21 microm, a working distance of approximately 11-12 mm, and a round-shape beam profile. The performance of the OCT balloon catheter was demonstrated by 3D full-circumferential imaging of a swine esophagus in vivo along with a high-speed, Fourier-domain, mode-locked swept-source OCT system.
Xi
Jiefeng
J
Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Huo
Li
L
Wu
Yicong
Y
Cobb
Michael J
MJ
Hwang
Joo Ha
JH
Li
Xingde
X
D000818:Animals; D016477:Artifacts; D002404:Catheterization / Q000379:methods*; D004947:Esophagus / Q000378:metabolism; D007909:Lenses; D055620:Optical Phenomena; D013552:Swine; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*