Monochorionic dizygotic twins in a spontaneous pregnancy: a rare case report.
Traditionally, monochorionicity in multiple pregnancies is associated with monozygocity. We present a case of a spontaneous, monochorionic dizygotic, sex-discordant twin pregnancy. The diagnosis of monochorionicity was initially done during first-trimester ultrasound evaluation and then confirmed by postnatal placental pathology. Furthermore, both twins were found to have blood chimerism. We also review the literature on dizygotic-monochorionic twins and blood-chimerism. We suggest that further prospective postnatal genetic studies are needed to define the reliability of prenatal diagnosis of identical twins in cases of monochorionicity.
Hackmon
Rinat
R
Department of Obstetrics and Gynecology, Lenox Hill Hospital, NY, NY 10025, USA. rhackmon@fhcrc.org
Jormark
Susan
S
Cheng
Vanessa
V
O'Reilly Green
Christopher
C
Divon
Michael Y
MY
D000328:Adult; D000650:Amnion / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D046528:Chimerism; D002823:Chorion / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011256:Pregnancy Outcome; D014429:Twins, Dizygotic / Q000235:genetics; D016216:Ultrasonography, Prenatal