[Selective death of the striatum neurons in rats after the transient occlusion of the middle cerebral artery].
The aim of the present investigation was to determine the neuronal population of rat telencephalon that was most sensitive to ischemic damage under the experimental condition of transient focal cerebral ischemia. It was found that 30-minute ischemia of the left hemisphere resulted in a significant decrease of neuronal population in the dorsomedial part of caudatoputamen. Local neural cell death was accompanied by a moderate activation of the astrocytes.
Kirik
O V
OV
Sukhorukova
E G
EG
Vlasov
T D
TD
Korzhevskiĭ
D E
DE
D000818:Animals; D016923:Cell Death; D003342:Corpus Striatum / Q000098:blood supply / Q000473:pathology*; D004195:Disease Models, Animal; D020244:Infarction, Middle Cerebral Artery / Q000473:pathology*; D002546:Ischemic Attack, Transient / Q000473:pathology*; D008297:Male; D009474:Neurons / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar