EUS-guided FNA aspiration of kidney masses: a multicenter U.S. experience.
BACKGROUND
Tissue sampling of renal lesions is traditionally performed with percutaneous US or CT guidance. To date, only 3 known cases of EUS-guided FNA (EUS-FNA) of a renal mass have been reported.


OBJECTIVE
To describe a multicenter experience with the indications, yield, and complications from attempted EUS-FNA of a kidney mass.


METHODS
Retrospective case series.


METHODS
Six tertiary referral hospitals in the United States.


METHODS
Consecutive subjects undergoing attempted EUS-FNA of a kidney mass. Endosonographers at 15 other teaching hospitals were contacted regarding EUS findings and follow-up of any EUS-guided renal biopsies previously attempted or considered at that institution.


METHODS
EUS-FNA of a kidney mass.


METHODS
Biopsy indications, yield, diagnosis, and complications.


RESULTS
Fifteen procedures in 15 patients (9 men; median age 67 years) were performed at 6 (37%) of 16 hospitals (Indiana University plus 15 other hospitals). Kidney masses (median diameter 32 mm; range 11-60 mm) were located in the upper (n = 12) and lower (n = 3) poles of the left (n = 10) and right (n = 5) kidneys, respectively. Initial mass detection was by previous imaging in 13 (87%) patients or by EUS in 2 (13%) patients. Results of EUS-FNA (median 3 passes; range 2-4 passes) in 13 (87%) procedures were diagnostic of (n = 7) or highly suspicious for (n = 1) renal cell carcinoma (RCC), atypical cells (n = 2), oncocytoma (n = 1), benign cyst (n = 1), and nondiagnostic (n = 1). No complications were encountered. Surgical resection confirmed RCC in 7 patients in whom preoperative EUS-FNA demonstrated RCC (n = 5) or oncocytoma (n = 1) or was not performed (n = 1).


CONCLUSIONS
Retrospective series, small number of patients.


CONCLUSIONS
EUS-FNA of renal masses is rarely performed at the U.S. teaching hospitals surveyed. This technique appears safe and feasible and should be considered when results would affect patient management.
DeWitt
John
J
Division of Gastroenterology and Hepatology, Indiana University Medical Center, Indianapolis, Indiana 43202, USA.
Gress
Frank G
FG
Levy
Michael J
MJ
Hernandez
Lyndon V
LV
Eloubeidi
Mohamad A
MA
Mishra
Girish
G
Sherman
Stuart
S
Al-Haddad
Mohammad A
MA
LeBlanc
Julia K
JK
D018249:Adenoma, Oxyphilic / Q000000981:diagnostic imaging / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle / Q000009:adverse effects / Q000379:methods*; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000473:pathology; D015331:Cohort Studies; D016001:Confidence Intervals; D019160:Endosonography / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006784:Hospitals, Teaching; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011336:Probability; D012189:Retrospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D014481:United States