title: Label-free optical imaging of mitochondria in live cells.
abstract: The far-field optical imaging of mitochondria of live cells without the use of any label is demonstrated. It uses a highly sensitive photothermal method and has a resolution comparable to confocal fluorescence setups. The morphological states of mitochondria were followed under different physiological treatments, and the role of cytochrome c was ruled out as the main origin of the photothermal signals. This label free optical method provides a high contrast imaging of live mitochondria and should find many applications in biosciences.
authors: David
authors: D
authors: Lasne
authors: Gerhard A
authors: GA
authors: Blab
authors: Francesca
authors: F
authors: De Giorgi
authors: François
authors: F
authors: Ichas
authors: Brahim
authors: B
authors: Lounis
authors: Laurent
authors: L
authors: Cognet