Copper-catalyzed aerobic phosphonation of sp3 C-H bonds.
An efficient cross-dehydrogenative-coupling (CDC) between sp3 C-H and H-P bonds was developed using copper salt as catalyst and molecular oxygen as terminal oxidant; this new methodology provides an easy access to biologically important alpha-aminophosphonates.
Baslé
Olivier
O
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, Canada H3A 2K6.
Li
Chao-Jun
CJ
D000332:Aerobiosis; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D044005:Tetrahydroisoquinolines / Q000138:chemical synthesis* / Q000737:chemistry
D063065:Organophosphonates; D044005:Tetrahydroisoquinolines; D003300:Copper