Clostridium difficile strains from community-associated infections.
Clostridium difficile isolates from presumed community-associated infections (n = 92) were characterized by toxinotyping, pulsed-field gel electrophoresis, tcdC and cdtB PCR, and antimicrobial susceptibility. Nine toxinotypes (TOX) and 31 PFGE patterns were identified. TOX 0 (48, 52%), TOX III (18, 20%), and TOX V (9, 10%) were the most common; three isolates were nontoxigenic.
Limbago
Brandi M
BM
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS C-16, Atlanta, GA 30333, USA. blimbago@cdc.gov
Long
Cherie M
CM
Thompson
Angela D
AD
Killgore
George E
GE
Hannett
George E
GE
Havill
Nancy L
NL
Mickelson
Stephanie
S
Lathrop
Sarah
S
Jones
Timothy F
TF
Park
Mahin M
MM
Harriman
Kathleen H
KH
Gould
L Hannah
LH
McDonald
L Clifford
LC
Angulo
Frederick J
FJ
D036002:ADP Ribose Transferases / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000032:analysis; D015373:Bacterial Typing Techniques; D016360:Clostridioides difficile / Q000145:classification* / Q000302:isolation & purification*; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000382:microbiology*; D016172:DNA Fingerprinting; D016521:Electrophoresis, Gel, Pulsed-Field; D004761:Enterocolitis, Pseudomembranous / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D016133:Polymerase Chain Reaction / Q000379:methods; D012097:Repressor Proteins / Q000235:genetics
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D012097:Repressor Proteins; C105615:TcdC protein, Clostridium difficile; D036002:ADP Ribose Transferases; C410164:actin-specific ADP-ribosyltransferase, Clostridium