title: Threshold determination in sweep VEP and the effects of criterion.
abstract: In order to develop criteria for the range of data points used for regression line fitting in sweep visually evoked potential (sVEP), which would be objective, clearly specified and give good repeatability and validity, and in order to investigate the effect of luminance on sVEP measurement, visual acuity (VA) and contrast sensitivity (CS) were measured with sVEP in adults aged 17-30 years and children aged 6-8 years. Six to ten participants took part in each experiment. Five criteria (C0-C4) for fitting the regression line were implemented. Test-retest repeatability and validity against psychophysical thresholds at three luminance levels were considered for thresholds and the number of acceptable readings. There were significant effects of criteria (repeated measures ANOVAs, P < 0.05). The criteria, C2 and C3 (based on the range over which the signal-to-noise ratio >or=1), consistently gave better VA and CS, more viable readings, better agreement with psychophysical thresholds in adults and better repeatability than the other criteria. In the case of adults, C2 gave thresholds that were not significantly different from the psychophysical thresholds (P > 0.05). There was little effect of luminance over the 25-100 cd/m(2) range used. Overall, C2 performed the best and would be the criterion of choice, giving better repeatability, better validity and more viable plots.
authors: University of Waterloo, Waterloo, ON, Canada.
authors: Naveen Kr
authors: NK
authors: Yadav
authors: Fahad
authors: F
authors: Almoqbel
authors: Liseann
authors: L
authors: Head
authors: Elizabeth L
authors: EL
authors: Irving
authors: Susan J
authors: SJ
authors: Leat
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D015350:Contrast Sensitivity / Q000502:physiology*; D004594:Electrophysiology / Q000592:standards*; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D008027:Light; D012044:Regression Analysis; D012684:Sensory Thresholds / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology