title: Nasal CPAP and surfactant for treatment of respiratory distress syndrome and prevention of bronchopulmonary dysplasia.
abstract: The Scandinavian approach is an effective combined treatment for respiratory distress syndrome (RDS) and prevention of bronchopulmonary dysplasia (BPD). It is composed of many individual parts. Of significant importance is the early treatment with nasal continuous positive airway pressure (nCPAP) and surfactant treatment. The approach may be supplemented with caffeine citrate and non-invasive positive pressure ventilation for apnoea. The low incidence of BPD seen as a consequence of the treatment strategy is mainly due to a reduced need for mechanical ventilation (MV).
  
  
  CONCLUSIONS
  Early-postnatal treatment with nCPAP and surfactant decreases the severity and mortality of RDS and BPD. This is mainly due to a diminished use of MV in the first days of life.
authors: Department of Paediatrics, Holbaek University Hospital, University of Copenhagen, Holbaek, Denmark. hav@regionsjaelland.dk
authors: Henrik
authors: H
authors: Verder
authors: Kajsa
authors: K
authors: Bohlin
authors: Jens
authors: J
authors: Kamper
authors: Robert
authors: R
authors: Lindwall
authors: Baldvin
authors: B
authors: Jonsson
mesh_terms: D001049:Apnea / Q000628:therapy; D001997:Bronchopulmonary Dysplasia / Q000517:prevention & control*; D002110:Caffeine / Q000627:therapeutic use; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D003131:Combined Modality Therapy; D045422:Continuous Positive Airway Pressure / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D011175:Positive-Pressure Respiration; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012121:Respiration, Artificial / Q000009:adverse effects; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
chemical_list: D000697:Central Nervous System Stimulants; D002951:Citrates; D011663:Pulmonary Surfactants; D002110:Caffeine; C026189:caffeine citrate