Severe osteomalacia presenting with multiple vertebral fractures: a case report and review of the literature.
Adequate exposure to sunlight and fortification of dairy products with vitamin D have eliminated vitamin D deficiency secondary to inadequate endogenous production or nutrition in the majority of countries. Insufficient vitamin D intake secondary to using unfortified foods and social customs (such as avoiding sun exposure), however, contribute to the development of disease. Poor diet, a lack of sun exposure, and the age related decline in the dermal synthesis of 7-dehydrocholesterol are among the factors that predispose to vitamin D deficiency and consequent bone disease. Here, we present a case of severe osteomalacia presenting with multiple vertebral fractures due to poor diet and a lack of exposure to sunlight.
Ukinc
Kubilay
K
Department of Endocrinology and Metabolism, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey. kukinc@comu.edu.tr
D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010018:Osteomalacia / Q000150:complications* / Q000473:pathology; D016103:Spinal Fractures / Q000209:etiology* / Q000473:pathology; D013472:Sunlight; D014808:Vitamin D Deficiency / Q000150:complications* / Q000473:pathology