title: Clarithromycin susceptibility testing of Mycobacterium avium complex using 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride microplate assay with Middlebrook 7H9 broth.
abstract: A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.
authors: Korean Institute of Tuberculosis, Seoul, Korea.
authors: Young Kil
authors: YK
authors: Park
authors: Won-Jung
authors: WJ
authors: Koh
authors: Shin Ok
authors: SO
authors: Kim
authors: Sonya
authors: S
authors: Shin
authors: Bum Joon
authors: BJ
authors: Kim
authors: Sang-Nae
authors: SN
authors: Cho
authors: Sun Min
authors: SM
authors: Lee
authors: Chulhun L
authors: CL
authors: Chang
mesh_terms: D017291:Clarithromycin / Q000494:pharmacology*; D003470:Culture Media; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015269:Mycobacterium avium Complex / Q000187:drug effects* / Q000302:isolation & purification; D013778:Tetrazolium Salts / Q000737:chemistry*
chemical_list: C494145:2,3-diphenyl-5-thienyl-(2)-tetrazolium; D003470:Culture Media; D013778:Tetrazolium Salts; D017291:Clarithromycin