title: Acute toxicity in five dogs after ingestion of a commercial snail and slug bait containing iron EDTA.
abstract: This case series of five dogs describes the effects of ingesting large amounts of an iron EDTA snail-bait product. In all cases signs of toxicity occurred between 6 and 24 h after ingestion and included abdominal pain and haemorrhagic gastroenteritis. Two of the dogs had pretreatment serum iron levels measured and in both cases the levels were above normal limits. All of the dogs were treated with iron chelation therapy and supportive care including intravenous fluids, analgesics, gastric protectants and antibiotics. Chelation therapy with desferrioxamine mesylate did not cause adverse effects in any of the dogs and all survived to discharge. The effects of iron EDTA snail bait in dogs requires further study and minimum toxic doses need to be established.
authors: University of Melbourne, Department of Veterinary Clinic and Hospital, 250 Princes Hwy, Werribee, Victoria 3030, Australia. haldanes@unimelb.edu.au
authors: S L
authors: SL
authors: Haldane
authors: R M
authors: RM
authors: Davis
mesh_terms: D000818:Animals; D003676:Deferoxamine / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy / Q000378:metabolism*; D004285:Dogs; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000378:metabolism / Q000662:veterinary*; D007501:Iron / Q000378:metabolism* / Q000633:toxicity; D008297:Male; D017262:Siderophores / Q000627:therapeutic use*
chemical_list: D017262:Siderophores; D007501:Iron; D003676:Deferoxamine