title: In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal.
abstract: In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as a model in the canine pelvic canal. Studies were taken longitudinally at prior to, 14 days after, and 35 days after the TVT injection. As the tumor grew, the nodules became increasingly hyperabsorptive and moderately hyperscattering on NIR. The regions of strong NIR contrast, especially on absorption images, correlated well with those of US hypoechoic masses indicative of tumors. Combining the information of trans-rectal NIR and US detected the tumor more accurately than did the US alone at 14 days postinjection.
authors: Zhen
authors: Z
authors: Jiang
authors: G Reed
authors: GR
authors: Holyoak
authors: Kenneth E
authors: KE
authors: Bartels
authors: Jerry W
authors: JW
authors: Ritchey
authors: Guan
authors: G
authors: Xu
authors: Charles F
authors: CF
authors: Bunting
authors: Gennady
authors: G
authors: Slobodov
authors: Daqing
authors: D
authors: Piao
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D007259:Infrared Rays; D008297:Male; D009368:Neoplasm Transplantation; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging; D010388:Pelvis / Q000000981:diagnostic imaging; D011467:Prostate / Q000000981:diagnostic imaging; D041622:Tomography, Optical / Q000379:methods*; D014463:Ultrasonography; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods*; D014685:Venereal Tumors, Veterinary / Q000000981:diagnostic imaging*