title: Amygdala inhibitory circuits and the control of fear memory.
abstract: Classical fear conditioning is a powerful behavioral paradigm that is widely used to study the neuronal substrates of learning and memory. Previous studies have clearly identified the amygdala as a key brain structure for acquisition and storage of fear memory traces. Whereas the majority of this work has focused on principal cells and glutamatergic transmission and its plasticity, recent studies have started to shed light on the intricate roles of local inhibitory circuits. Here, we review current understanding and emerging concepts of how local inhibitory circuits in the amygdala control the acquisition, expression, and extinction of conditioned fear at different levels.
authors: Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland.
authors: Ingrid
authors: I
authors: Ehrlich
authors: Yann
authors: Y
authors: Humeau
authors: François
authors: F
authors: Grenier
authors: Stephane
authors: S
authors: Ciocchi
authors: Cyril
authors: C
authors: Herry
authors: Andreas
authors: A
authors: Lüthi
mesh_terms: D000679:Amygdala / Q000166:cytology / Q000502:physiology*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D003214:Conditioning, Classical / Q000502:physiology; D005108:Extinction, Psychological; D005239:Fear; D006801:Humans; D008568:Memory / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D009433:Neural Inhibition / Q000502:physiology*