Mineralization potential of polarized dental enamel.
BACKGROUND
Management of human teeth has moved from a surgical to a more conservative approach of inhibiting or preventing lesion progression. Increasing enamel mineralization is crucial in this regard. A potential difficulty is the preferential mineralization of the outermost portion of the enamel that can prevent overall mineralization. We describe a strategy for increasing the mineralization potential of dental enamel.


RESULTS
Extracted human premolar teeth enamel (n = 5) were exposed to a high concentration of hydrogen peroxide with an energizing source. Samples were stored in artificial saliva at 37 degrees C for 1 wk. A desktop X-ray micro-CT system was used to evaluate the mineral density of samples. Mineral distribution was polarized between the lower and the higher mineralized portion of enamel by charged oxygen free radicals due to activation of permeated hydrogen peroxide. The kinetics of energy absorption in the deeper enamel region demonstrated improvement of preferential mineralization into the region without restricting overall mineralization of the enamel. Subsequent increasing mineralization, even in the dense mineralized outer portion of enamel, was also achieved.


CONCLUSIONS
This increased mineralization may promote resistance to acidic deterioration of the structure. The present study is one of the primary steps towards the development of novel application in reparative and restorative dentistry.
Tanaka
Reina
R
Department of Oral Biomaterials and Technology, Showa University School of Dentistry, Tokyo, Japan.
Shibata
Yo
Y
Manabe
Atsufumi
A
Miyazaki
Takashi
T
D015519:Bone Density; D003743:Dental Enamel / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007700:Kinetics; D017001:Tooth Demineralization; D014089:Tooth Remineralization; D055114:X-Ray Microtomography