title: Effectiveness of a multidisciplinary program for management of obesity: the Unité d'Enseignement, de Traitement et de Recherche sur l'Obésité (UETRO) database study.
abstract: BACKGROUND
  Obesity is a worldwide health problem assuming epidemic proportions. Development of effective clinical interventions is needed to lower the impact of associated morbidity and mortality, without forgetting related costs. We have established an interdisciplinary clinic for obesity management, Unité d'Enseignement, de Traitement et de Recherche sur l'Obésité (UETRO), which consists of individual consultations combined with group sessions. We report here the effectiveness of this program for weight reduction over the first year of follow up.
  
  
  METHODS
  We performed retrospective analysis of standardized patient records of the first 115 consecutive subjects referred to UETRO with available follow up for 1 year.
  
  
  RESULTS
  Mean age, body mass index (BMI), and waist circumference (WC) of our cohort were 46 +/- 13 years, 44.7 +/- 0.9 kg/m(2), and 120.5 +/- 1.9 cm, respectively. Hypertension and diabetes were present in 46% and 23% of our patients. Weight and WC loss were gradual over 1 year and were significantly reduced by 6.6 +/- 0.8 kg and 6.7 +/- 0.7 cm, respectively (P < 0.001), without attainment of a plateau. Blood pressure and lipid profile significantly improved after 1 year of follow up. However, the proportion of patients taking metformin, lipid-lowering, antihypertensive, or antiobesity drugs increased significantly over follow up, reflecting intensification of treatment of co-morbidities and weight management. Significant weight and WC loss occurred independently of diabetes status and use of antiobesity medications.
  
  
  CONCLUSIONS
  This program appears to be as effective for treating obesity as more intensive treatment programs. Future prospective studies are needed to evaluate the benefits and costs of this therapeutic approach.
authors: Department of Medicine, Division of Endocrinology, Centre de Recherche Clinique Etienne-Le Bel, Centre Hospitalier Universitaire de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Québec, Canada.
authors: Carole N
authors: CN
authors: Kamga-Ngandé
authors: André C
authors: AC
authors: Carpentier
authors: Frédérique
authors: F
authors: Nadeau-Marcotte
authors: Jean-Luc
authors: JL
authors: Ardilouze
authors: Jean-Patrice
authors: JP
authors: Baillargeon
authors: Diego
authors: D
authors: Bellabarba
authors: Ghislaine
authors: G
authors: Houde
authors: Marie-France
authors: MF
authors: Langlois
mesh_terms: D000328:Adult; D019440:Anti-Obesity Agents / Q000627:therapeutic use; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D015331:Cohort Studies; D016208:Databases, Factual; D048909:Diabetes Complications / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000401:mortality / Q000628:therapy*; D012189:Retrospective Studies; D055105:Waist Circumference
chemical_list: D019440:Anti-Obesity Agents