title: Epstein-Barr virus-induced infectious mononucleosis after two separate episodes of virus-associated hemophagocytic syndrome.
abstract: A 24-year-old man, who had suffered previous two episodes of non- Epstein-Barr virus (EBV)-associated hemophagocytic syndrome (HPS) at the ages of 16 and 18, developed EBV-induced infectious mononucleosis. His antibody pattern to EBV highlighted the initial infection. The disease took a self-limited course without developing into HPS. No reactivation of EBV infection was noted over the following 6 years. The patient may have attained immune competency in adulthood, which was somehow impaired during his adolescence.
authors: Division of Hematology and Immunology, Department of Internal Medicine, Ohtsu Red Cross Hospital, Shiga. tatsohno@otsu.jrc.or.jp
authors: Tatsuharu
authors: T
authors: Ohno
authors: Yo
authors: Y
authors: Ueda
authors: Wataru
authors: W
authors: Kishimoto
authors: Kazue
authors: K
authors: Arimoto-Miyamoto
authors: Tomoharu
authors: T
authors: Takeoka
authors: Masaaki
authors: M
authors: Tsuji
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000209:etiology / Q000276:immunology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000209:etiology / Q000276:immunology; D008297:Male; D013997:Time Factors; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral