Relationships between mandibular cortical bone measures and biochemical markers of bone turnover in elderly Japanese men and women.
OBJECTIVE
The aim was to clarify the association between dental panoramic radiography measures of mandibular inferior cortical shape and biochemical markers of bone turnover in elderly men and women.


METHODS
Subjects were 80-year-old men (n = 85) and women (n = 153). Mandibular cortical shape and width were evaluated on dental panoramic radiographs. Bone formation and resorption, respectively, were estimated by serum levels of carboxy-terminal propeptide of type I collagen (PICP) and serum type I collagen carboxy-terminal telopeptide (ICTP).


RESULTS
Eroded cortices of the mandible were significantly associated with increased serum PICP levels (P = .005) in women. Lower mandibular cortical width quartiles were also significantly associated with increased serum PICP levels in men (P = .020) and women (P = .006).


CONCLUSIONS
Mandibular inferior cortical measures detected on dental panoramic radiographs may be associated with bone formation rates and be useful in predicting osteoporosis in elderly Japanese men and women.
Morita
Ichizo
I
Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan. ichizo@dpc.aichi-gakuin.ac.jp
Nakagaki
Haruo
H
Taguchi
Akira
A
Kato
Kazuo
K
Murakami
Taeko
T
Tsuboi
Shinji
S
Hayashizaki
Junko
J
Inagaki
Koji
K
Noguchi
Toshihide
T
D000368:Aged; D015415:Biomarkers / Q000097:blood; D016723:Bone Remodeling; D024042:Collagen Type I; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging*; D010024:Osteoporosis / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D010455:Peptides; D011237:Predictive Value of Tests; D011347:Procollagen / Q000097:blood*; D011862:Radiography, Panoramic; D012737:Sex Factors
D015415:Biomarkers; D024042:Collagen Type I; D010446:Peptide Fragments; D010455:Peptides; D011347:Procollagen; C052929:collagen type I trimeric cross-linked peptide; C042813:procollagen type I carboxy terminal peptide