On-chip detection of cellular activity.
The use of on-chip cellular activity monitoring for biological/chemical sensing is promising for environmental, medical and pharmaceutical applications. The miniaturization revolution in microelectronics is harnessed to provide on-chip detection of cellular activity, opening new horizons for miniature, fast, low cost and portable screening and monitoring devices. In this chapter we survey different on-chip cellular activity detection technologies based on electrochemical, bio-impedance and optical detection. Both prokaryotic and eukaryotic cell-on-chip technologies are mentioned and reviewed.
Almog
R
R
Department of Physical Electronics, School of Electrical Engineering, Faculty of Engineering, Tel-Aviv University, Tel-Aviv, 69978, Israel, almogr@tx.technion.ac.il.
Daniel
R
R
Vernick
S
S
Ron
A
A
Ben-Yoav
H
H
Shacham-Diamand
Y
Y
D015374:Biosensing Techniques; D002477:Cells / Q000166:cytology*; D058266:Dielectric Spectroscopy; D004563:Electrochemistry; D055620:Optical Phenomena; D046888:Tissue Array Analysis / Q000379:methods*