Human clinical fitting study of the DexAide right ventricular assist device.
The DexAide right ventricular assist device (RVAD) has been developed as an implantable RVAD. The purpose of this study was to determine the final design and optimal anatomical placement of the DexAide RVAD when implanted simultaneously with either of two commercially available left ventricular assist devices (LVADs) in patients. A mock-up DexAide RVAD was used to assess configuration with each of two types of commercially available LVADs at the time of LVAD implantation in three human clinical cases. The pump body of the DexAide RVAD was placed either in the preperitoneal space or in the right thoracic cavity. The DexAide RVAD placed into the right thoracic cavity is suitable for use with the Novacor or HeartMate II LVADs. The results of this study will guide the finalization of the inflow cannula and optimal placement of the DexAide RVAD for human clinical trials.
Ootaki
Yoshio
Y
Department of Thoracic and Cardiovascular Surgery, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Ootaki
Chiyo
C
Massiello
Alex
A
Horvath
David
D
Chen
Ji-Feng
JF
Mihaljevic
Tomislav
T
Navia
Jose L
JL
Smedira
Nicholas G
NG
Golding
Leonard A R
LA
Fukamachi
Kiyotaka
K
D000328:Adult; D000368:Aged; D004867:Equipment Design; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D019919:Prosthesis Implantation; D018497:Ventricular Dysfunction, Right / Q000628:therapy*