title: Brainstem involvement in Sjögren's syndrome-related sensory neuronopathy.
abstract: OBJECTIVE
  Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns.
  
  
  RESULTS
  A 65-year-old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI.
  
  
  CONCLUSIONS
  Sjögren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN.
authors: Departments of Neurology, School of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil. alfredodamasceno@hotmail.com
authors: Alfredo
authors: A
authors: Damasceno
authors: Marcondes C
authors: MC
authors: França
authors: Verônica A
authors: VA
authors: Zanardi
authors: Anamarli
authors: A
authors: Nucci
mesh_terms: D001933:Brain Stem / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D011115:Polyneuropathies / Q000473:pathology*; D012678:Sensation Disorders / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000473:pathology*