title: The role of adults in household outbreaks of pertussis.
abstract: OBJECTIVE
  This study describes the role of adults in 57 household outbreaks of pertussis.
  
  
  METHODS
  Parents/guardians of children with suspected pertussis seen at a university hospital were interviewed. Once a case of pertussis was confirmed, all household members were enrolled in the study. The US Centers for Disease Control and Prevention (CDC) definitions for pertussis were used .
  
  
  RESULTS
  Among 349 household members, 150 were adults and one in five had pertussis during the household outbreaks. Of the adult cases, 70.6% were aged 19-39 years. The secondary attack rate in adults was 12.6%. Adults were the primary case in a 21.1% of households, resulting in 43% of all secondary cases. Most adult cases had typical symptoms of pertussis, but none had been diagnosed before the investigation.
  
  
  CONCLUSIONS
  Adults, particularly those aged between 19 and 39 years, play an important role in pertussis transmission in households. Pertussis vaccination in adolescents/young adults may decrease the dissemination of pertussis in households.
authors: Pediatric Infectious Disease Service, University of Pernambuco School Hospital, Rua Arnóbio Marques 310, CEP 50100-130, Recife, Brazil. paulonbaptista@terra.com.br
authors: P N
authors: PN
authors: Baptista
authors: V S
authors: VS
authors: Magalhães
authors: L C
authors: LC
authors: Rodrigues
mesh_terms: D000293:Adolescent; D000328:Adult; D001886:Bordetella pertussis / Q000302:isolation & purification*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005191:Family Characteristics; D005260:Female; D006801:Humans; D008297:Male; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D018571:Sentinel Surveillance; D014611:Vaccination / Q000706:statistics & numerical data; D014917:Whooping Cough / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control* / Q000635:transmission*; D055815:Young Adult
chemical_list: D010567:Pertussis Vaccine