title: Two flavonoid dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY.
abstract: Two new flavonoid dimers (1, 2) consisting of flavan-chalcone together with three known compounds (3-5) were isolated from the ethanol extract of the whole plants of Sarcandra hainanensis. Their structures were determined by extensive spectroscopic analysis. Human immunodeficiency virus-1 integrase inhibition activities of compounds 1 and 2 were evaluated and they showed weak activities with IC(50) at 18.05 and 25.27 muM, respectively.
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College.
authors: Cong-Mei
authors: CM
authors: Cao
authors: Yong
authors: Y
authors: Peng
authors: Li-Jia
authors: LJ
authors: Xu
authors: Ya-Jun
authors: YJ
authors: Wang
authors: Jun-Shan
authors: JS
authors: Yang
authors: Pei-Gen
authors: PG
authors: Xiao
mesh_terms: D004791:Enzyme Inhibitors; D047309:Flavones / Q000737:chemistry*; D019427:HIV Integrase; D019684:Magnoliopsida / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D004791:Enzyme Inhibitors; D047309:Flavones; D019427:HIV Integrase; C514801:p31 integrase protein, Human immunodeficiency virus 1