Lesion location and repeatable battery for the assessment of neuropsychological status performance in acute ischemic stroke.
The validity of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) was evaluated in a sample of acute ischemic stroke patients. A total of 164 ischemic stroke patients with anterior fossa lesions were divided into groups according to lesion laterality (left, right, or bilateral) and location (cortical versus subcortical) as determined by CT and/or MRI findings. The hypotheses for this study were: (1) that left hemispheric stroke patients would perform better than their counterparts on the Visuospatial/Constructional and Attention Indexes; (2) that right hemisphere stroke patients would outperform their counterparts on the Immediate Memory, Delayed Memory, and Language Indexes; (3) that patients with subcortical lesions would outperform those with cortical lesions on the Language, Immediate Memory, and Delayed Memory indexes; and (4) that patients with cortical lesions would outperform those with subcortical lesions on the Attention and Visuospatial/Constructional Indexes. A multivariate analysis of variance (MANOVA) disclosed significant main effects for both lesion side and location, with no location by side interaction. Group comparisons of the five RBANS index scores disclosed modest effects for side of lesion, with right hemisphere patients outperforming those with left sided and bilateral lesions on the Immediate and Delayed Memory, and Language Index Scores. Right hemisphere stroke patients also outperformed left and bilateral lesion patients on the Attention Index. The left hemisphere patients outperformed the right hemisphere and bilateral patients on the Visuospatial/Constructional Index. The effect for location was significant only for the Visuospatial/Constructional Index where the subcortical patients outperformed the cortical patients.
Wilde
M C
MC
Department of Physical Medicine and Rehabilitation, The University of Texas Medical School-Houston Memorial Hermann Hospital, Houston, TX 77030, USA. mark.c.wilde@uth.tmc.edu
D000328:Adult; D000368:Aged; D001288:Attention / Q000502:physiology; D002545:Brain Ischemia / Q000150:complications; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology; D015203:Reproducibility of Results; D020521:Stroke / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D015898:Tomography Scanners, X-Ray Computed; D014796:Visual Perception / Q000502:physiology