title: Epidemiology of antimicrobial resistance among gram-negative organisms recovered from patients in a multistate network of long-term care facilities.
abstract: We identified 1,805 gram-negative organisms in cultures of urine samples obtained over a 10-month period from residents of 63 long-term care facilities. The prevalence of fluoroquinolone resistance in Escherichia coli was 51% (446 of 874 isolates), whereas the prevalences of ceftazidime and imipenem resistance in Klebsiella species were 26% and 6% (84 and 19 of 323 isolates), respectively. The prevalence of resistance varied significantly by facility type, size, and geographic location.
authors: Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA. ebbing@mail.med.upenn.edu
authors: Ebbing
authors: E
authors: Lautenbach
authors: Roseann
authors: R
authors: Marsicano
authors: Pam
authors: P
authors: Tolomeo
authors: Michael
authors: M
authors: Heard
authors: Steve
authors: S
authors: Serrano
authors: Donald D
authors: DD
authors: Stieritz
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D015169:Colony Count, Microbial; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000652:urine; D003430:Cross-Sectional Studies; D003691:Delaware / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification; D024841:Fluoroquinolones / Q000627:therapeutic use; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000652:urine; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D007709:Klebsiella / Q000187:drug effects / Q000302:isolation & purification; D008134:Long-Term Care / Q000706:statistics & numerical data; D008826:Microbial Sensitivity Tests; D009515:New Jersey / Q000453:epidemiology; D010414:Pennsylvania / Q000453:epidemiology; D015995:Prevalence; D011513:Proteus mirabilis / Q000187:drug effects / Q000302:isolation & purification; D012866:Skilled Nursing Facilities / Q000706:statistics & numerical data*
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D015378:Imipenem; D002442:Ceftazidime