[Use of non-invasive ventilation in acute respiratory failure. Multicenter study in intensive care units].
OBJECTIVE
Study the use of non-invasive ventilation (NIV) in patients with acute respiratory failure in intensive care units (ICUs) in Spain.


METHODS
A questionnaire was sent to 254 ICUs, after which, they were invited to participate in a multicenter, retrospective study, providing detailed information on ventilated patients.


RESULTS
Answers were received from 123 hospitals. Of these, 119 used NIV, although its use varied greatly. NIV is the treatment of choice in 89% of the units for chronic obstructive pulmonary disease (COPD), in 79% for acute pulmonary edema (APE), in 53% for postextubation failure, in 53% for pneumonia 53%, and in 17% for acute respiratory distress syndrome (ARDS). It was used occasionally in COPD in 11% of the units, and in 21% of the units for APE. Eighteen hospitals provided additional information on 432 ventilated patients, 232 (54%) of whom received NIV as first line therapy. Presence of pneumonia or acute respiratory distress syndrome (ARDS) was an independent predictive factor of NIV failure (ORa=5.71; CI 95%, 1.83-17.8; p=0.003). Admission in a unit with experience in NIV in >50 patients/year (ORa=0.22; CI 95%, 0.07-0.63; p=0.005) and a higher PaO2/FiO2 ratio after one hour of ventilation (ORa=0.98 per point; CI 95%, 0.97-0.99; p<0.001) were protector factors.


CONCLUSIONS
In Spain, NIV is widely used but it may continue to be underused in COPD and APE. The diagnosis of pneumonia or ARDS was an independent predictive risk factor. Admission in an ICU with NIV in more than 50 patients/year also have higher PaO2/FiO2 ratio after one hour of ventilation were predictive factors of success.
Fernández-Vivas
Miguel
M
Unidad de Cuidados Intensivos, Hospital Virgen de la Arrixaca, Murcia, Spain. mfvivas@ono.com
González-Díaz
Gumersindo
G
Caturla-Such
Juan
J
Delgado-Vílchez
Francisco José
FJ
Serrano-Simón
José Manuel
JM
Carrillo-Alcaraz
Andrés
A
Vayá-Moscardó
José
J
Galcerá-Tomás
José
J
Jaime-Sánchez
Francisco Angel
FA
Solera-Suárez
Manuel
M
D000208:Acute Disease; D000368:Aged; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial / Q000379:methods*; D012131:Respiratory Insufficiency / Q000628:therapy*; D012189:Retrospective Studies