title: Asymmetric construction of binaphthyl by the chiral diether-mediated conjugate addition of naphthyllithium to naphthalenecarboxylic acid 2,6-di-t-butyl-4-methoxyphenyl ester.
abstract: Two ways for the synthesis of binaphthyl were examined based on a chiral ligand-mediated asymmetric conjugate addition of 1-naphthyllithium to naththalene-2-carboxylic acid 2,6-di-t-butyl-4-methoxyphenyl esters. The one pot method by conjugate addition-elimination gave a relatively higher enantioselectivity than the two step synthesis based on addition and subsequent oxidative aromatization.
authors: Institute for Materials Chemistry and Engineering, Kyushu University.
authors: Mitsuru
authors: M
authors: Shindo
authors: Yasutomo
authors: Y
authors: Yamamoto
authors: Ken-Ichi
authors: K
authors: Yamada
authors: Kiyoshi
authors: K
authors: Tomioka
mesh_terms: D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*
chemical_list: D009281:Naphthalenes; C542457:naphthalenecarboxylic acid 2,6-di-t-butyl-4-methoxyphenyl ester; C542456:naphthyllithium