An unusual squamo-melanocytic tumor of uncertain biologic behavior: a variant of melanoma?
The presence of two intermingled malignant components within the same cutaneous tumor is rare. Herein, we report a case of an exceedingly rare squamo-melanocytic tumor, favored to be a melanoma variant. Although the biologic behavior and prognostic significance of this tumor remain to be established, this unique case reaffirms the potential morphologic diversity of melanoma. We review the literature reporting similar neoplasms and discuss the potential histogenesis of this squamo-melanocytic tumor.
Pouryazdanparast
Pedram
P
Department of Pathology, University of Michigan, Ann Arbor, MI 48109-0602, USA.
Yu
Limin
L
Johnson
Timothy
T
Fullen
Douglas
D
D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D004428:Ear Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008545:Melanoma / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D018193:Neoplasms, Complex and Mixed / Q000378:metabolism / Q000473:pathology*; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*