Fluoroquinolone treatment of chronic bacterial prostatitis: a prospective cohort study.
A cohort study of patients (pts) presenting with symptoms of chronic prostatitis over 2 years was performed. Appropriate antimicrobials were administered to confirmed cases of chronic bacterial prostatitis (CBP) after a Stamey-meares (S-M) test for a period of 6 weeks and the test was repeated 1 and 6 months post therapy completion. 145 male patients presented for evaluation. the most prevalent symptoms included dysuria (68%), frequency (38%), and pain which was present in 50%. S-M testing was performed in 69% and expressed prostatic specimen was collected in 53.8%. the diagnosis of CBP was established in 26.9% of the total cohort. Escherichia coli (28.2%) and Enterococcus spp (23.1%) were the most frequently implicated pathogens and ciprofloxacin the most commonly prescribed antimicrobial. A 12-month follow-up was completed in 87% of the pts and 35.3% relapsed a mean of 4.75 months after the initial treatment.
Panagopoulos
P
P
4th Department of Internal Medicine, University General Hospital ATTIKON, Athens, Greece. ppanag@med.uoa.gr
Antoniadou
A
A
Kanellakopoulou
K
K
Tsiodras
S
S
Katsarolis
I
I
Papadopoulos
A
A
Galani
L
L
Giamarellou
H
H
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use; D015331:Cohort Studies; D024841:Fluoroquinolones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011472:Prostatitis / Q000175:diagnosis / Q000188:drug therapy*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D002939:Ciprofloxacin