Determinations of MC-LR and [Dha(7)] MC-LR concentrations and physicochemical properties by liquid chromatography-tandem mass spectrometry.
A liquid chromatography electrospray mass spectrometry (LC/ESI/MS) method working in multiple reactions monitoring mode for the determination of trace amounts of microcystin variants (MC-LR and [Dha(7)] MC-LR) in waters was developed. The limit of quantification was 0.05 microg/L and the limit of detection was 0.015 microg/L for MC-LR and [Dha(7)] MC-LR, respectively. Recoveries for MCs were in the range of 68%-81%. MC-LR and [Dha(7)] MC-LR were chemically stable with similar physiochemical behavior.
Yu
Ting
T
Donghu Experimental Station of Lake Ecosystems, State Key Laboratory of Freshwater Ecology and Biotechnology of China, Institute of Hydrobiology, Chinese Academy of Science, Wuhan 430072, People's Republic of China. fs-6215550@yeah.net
Xie
Ping
P
Dai
Ming
M
Liang
Gaodao
G
D002853:Chromatography, Liquid / Q000379:methods*; D008387:Marine Toxins; D052998:Microcystins / Q000032:analysis*; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods*
D008387:Marine Toxins; D052998:Microcystins; C057862:cyanoginosin LR