title: Acute presentation of nasal-type natural killer/T-cell lymphoma of the orbit.
abstract: OBJECTIVE
  An unusual case of nasal-type natural killer/T-cell lymphoma (NKTL) of the orbit is reported.
  
  
  METHODS
  The clinical history, computed tomography, magnetic resonance imaging, and biopsy specimen of a 29-year-old man with a right orbital lymphoma were evaluated.
  
  
  RESULTS
  The patient initially presented with conjunctival injection and had flu-like symptoms before developing right proptosis and reduced vision; imaging showed a diffuse infiltrative process throughout the orbit. Orbital biopsy revealed angiodestruction with prominent necrosis, and angiocentric lymphoma growth and lymphoma cells were positively stained for CD3, CD20, CD45RO, CD56, cytotoxic molecules (granzyme B and T-cell intracellular antigen-1), and Epstein-Barr virus.
  
  
  CONCLUSIONS
  NKTL is rare and may present acutely; the imaging findings presented serve to highlight the radiologic features of the disease.
authors: Southwest Eye Hospital/Southwest Hospital, Third Military Medical University, Chongqing - China. weiqin0707@163.com
authors: Wei
authors: W
authors: Qin
authors: Zhengqin
authors: Z
authors: Yin
authors: Simon N
authors: SN
authors: Madge
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D003229:Conjunctival Diseases / Q000175:diagnosis; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005094:Exophthalmos / Q000175:diagnosis; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use; D014786:Vision Disorders / Q000175:diagnosis
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor; D005938:Glucocorticoids; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone