A reader for centromeric chromatin.
For nucleosome-encoded epigenetic information to be transmitted, an epigenetic mark requires a 'reader' for its physical recognition. CENP-N has now been identified as a reader of the centromere-specifying epigenetic mark that is generated by incorporation of the histone H3 variant CENP-A into centromeric nucleosomes.
Sekulic
Nikolina
N
Black
Ben E
BE
D000818:Animals; D001324:Autoantigens / Q000378:metabolism / Q000502:physiology; D002503:Centromere / Q000235:genetics / Q000378:metabolism*; D000076247:Centromere Protein A; D002843:Chromatin / Q000235:genetics / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism / Q000502:physiology; D044127:Epigenesis, Genetic / Q000235:genetics; D006801:Humans; D008954:Models, Biological; D009707:Nucleosomes / Q000235:genetics / Q000378:metabolism
D001324:Autoantigens; C000619700:CENPA protein, human; D000076247:Centromere Protein A; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D009707:Nucleosomes