Intramolecular thermal allenyne [2 + 2] cycloadditions; facile construction of the 5-6-4 ring core of sterpurene.
A variety of 1-allenyl-2-propargyl-substituted cyclopentanol derivatives were found to undergo facile intramolecular microwave-assisted 2+2 alleneyne cycloaddition reactions to generate tricyclic 5-6-4 ring systems present in the sterpurenes.
Ovaska
Timo V
TV
Department of Chemistry, Connecticut College, 270 Mohegan Avenue, New London, CT 06320, USA.
Kyne
Robert E
RE