title: An uncommon folliculosebaceous cystic hamartoma on the lower extremity.
abstract: BACKGROUND
  Folliculosebaceous cystic hamartomas (FSCH) are a recently recognized cutaneous hamartoma comprised of follicular, sebaceous and mesenchymal elements. Only nine cases have been previously reported. The authors present a case of FSCH on the lower extremity in addition to a literature review.
  
  
  OBJECTIVE
  To further characterize the clinical, histological and immunohistological features of FSCH.
  
  
  METHODS
  The clinical, histological and immunohistological features of FSCH were evaluated and the literature reviewed.
  
  
  RESULTS
  This lesion uncommonly presents as exophytic papules or nodules on the leg, and most commonly presents on the central part of the face. Clinical differential diagnoses included nevus, neurofibroma and adnexal tumour. The diagnostic microscopic features of infundibular cystic structures with attached sebaceous glands and characteristic stroma were present in all lesions. Many of the stromal spindle cells were CD34-positive.
  
  
  CONCLUSIONS
  The FSCH is a recently recognized hamartoma comprised of follicular, sebaceous and mesenchymal elements. Although reported only rarely, its incidence is likely much higher. In the present patient, the FSCH was located in femoral region, which is very rare.
authors: Department of Plastic and Reconstructive Surgery, Numune State Hospital, Erzurum, Turkey.
authors: Ilteris Murat
authors: IM
authors: Emsen
authors: Ayten
authors: A
authors: Livaoglu