[Comparison of lead concentration and isotope ratios in children's blood and hair].
OBJECTIVE
To explore the characters of lead isotope ratios in children blood and hair, in order to obtain new data of the cumulated lead sources of human body.


METHODS
28 children in Beijing area were randomly sampled to take blood and hair with a 1:1 sex ratio, half of them from the city and the others from the village. The lead concentrations and isotope ratios in the samples were then determined by ICP-MS.


RESULTS
Lead isotope ratios in blood had significant differences between the children living in the city and those in the village, while no lead isotope ratio differences in hair could be found between the children living in the two area. The lead isotope ratios in children blood were significantly different from those in children hair in both area, in the other words, the lead fingerprints were different between blood and hair.


CONCLUSIONS
(1) The concentrations of lead pollution of children were resemble between the city and village in Beijing, but the lead sources in the city and village might be different from each other. (2) Organs or tissues in human body might have its own mechanism to accumulate the lead isotopes. (3) It was necessary to study if the lead in hair could be used as a biomarker of lead source.
Liu
Jingxiu
J
School of Public Health, Peking University, Beijing 100083, China. xiugeer@yahoo.com.cn
Wang
Xiaoyan
X
Zeng
Jing
J
Chen
Xi
X
D002648:Child; D002681:China; D004781:Environmental Exposure; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007554:Isotopes / Q000097:blood* / Q000378:metabolism; D007854:Lead / Q000097:blood* / Q000378:metabolism; D008297:Male
D007554:Isotopes; D007854:Lead