Restless legs syndrome.
Restless legs syndrome (RLS) affects many people. General population prevalence surveys usually range from 1% to 12%, but most European ancestry studies suggest 10%. The development of validated rating scales and standardized diagnostic criteria have vastly improved the quality of RLS treatment trials. Although multiple medications have shown outstanding efficacy, all of them are felt to provide only symptomatic relief, rather than any "curative" effect. Dopamine agonists are clearly the best investigated and probably the most effective treatments for RLS.
Ondo
William G
WG
Department of Neurology, Baylor College of Medicine, Houston, TX, USA. hwondo@bcm.tmc.edu
D000818:Animals; D001569:Benzodiazepines / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D018491:Dopamine Agonists / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease; D006801:Humans; D009068:Movement / Q000187:drug effects / Q000502:physiology; D010507:Periodicity; D015995:Prevalence; D044469:Racial Groups; D012148:Restless Legs Syndrome / Q000188:drug therapy* / Q000453:epidemiology* / Q000235:genetics; D012890:Sleep
D018491:Dopamine Agonists; D001569:Benzodiazepines