Determination of perchlorate in river by ion-pair hollow-fiber liquid-phase microextraction coupled with electrospray ionization tandem mass spectrometry.
This paper describes the analysis of perchlorate (ClO(4)(-)) in surface water samples by a rapid and reliable ion-pair hollow-fiber liquid-phase microextraction (HF-LPME) method coupled with flow-injection electrospray ionization tandem mass spectrometry (ESI-MS-MS) technique. The effects of the type and concentration of ion-pairing reagents, extraction time, temperature and pH value on the quantitative extraction of perchlorate by ion-pair HF-LPME were investigated and optimized. Di-n-hexyl ammonium acetate (DHAA) was employed to form an extractable ion-pair complex with aqueous perchlorate. The characteristic ions [ClO(4)-ClO(4)-DHA](-) at m/z 384.6 and 386.7 were observed in the ESI negative-ionization mode. The predominant product ions [ClO(4)](-) at m/z 99 and 101 were used for quantitation and to maximize the detection selectivity and sensitivity. The limit of detection (LOD) was 0.5 microg/L. The reliability and precision of the standard addition method of ion-pair HF-LPME for the determination of trace levels of perchlorate in surface water were demonstrated.
Chen
Hsin-Chang
HC
Department of Chemistry, National Central University, Chung-Li 320, Taiwan.
Chen
Wen-Tsen
WT
Ding
Wang-Hsien
WH
D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D010472:Perchlorates / Q000032:analysis* / Q000302:isolation & purification; D015203:Reproducibility of Results; D045483:Rivers / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods / Q000592:standards*; D053719:Tandem Mass Spectrometry; D013696:Temperature; D014874:Water Pollutants, Chemical / Q000032:analysis*
D007202:Indicators and Reagents; D010472:Perchlorates; D014874:Water Pollutants, Chemical; C494474:perchlorate