title: Prognostic value of motor evoked potentials in motor function recovery of upper limb after stroke.
abstract: OBJECTIVE
  To determine the prognostic value of clinical assessment and motor evoked potentials for upper limb strength and functional recovery after acute stroke, and to establish the possible use of motor evoked potentials in rehabilitation.
  
  
  METHODS
  A prospective study.
  
  
  METHODS
  Fifty-two patients with hemiparesis were enrolled one month post-stroke; 38 patients concluded the study at 12 months.
  
  
  METHODS
  Motor evoked potentials were recorded at baseline and after one month. Upper limb muscular strength (Medical Research Council Scale, MRC) and functional tests (Frenchay Arm Test, Barthel Index) were used as dependent outcome variables 12 months later. Motor evoked potentials were classified as present or absent. Predictive values of motor evoked potentials and MRC were evaluated.
  
  
  RESULTS
  At 12 months, patients with baseline recordable motor evoked potentials showed a good functional recovery (positive predictive value 94%). The absence of motor evoked potentials did not exclude muscular strength recovery (negative predictive value 95%). Motor evoked potentials had a higher positive predictive value than MRC only in patients with MRC < 2.
  
  
  CONCLUSIONS
  Motor evoked potentials could be a supportive tool to increase the prognostic accuracy of upper limb motor and functional outcome in hemiparetic patients, especially those with severe initial paresis (MRC < 2) and/or with motor evoked potentials absent in the post-stroke acute phase.
authors: Department of Neurorehabilitation, Fondazione Don Carlo Gnocchi Onlus IRCCS Centro S. Maria agli Ulivi, Pozzolatico, Florence, Italy. apizzi@dongnocchi.it
authors: Assunta
authors: A
authors: Pizzi
authors: Riccardo
authors: R
authors: Carrai
authors: Catuscia
authors: C
authors: Falsini
authors: Monica
authors: M
authors: Martini
authors: Sonia
authors: S
authors: Verdesca
authors: Antonello
authors: A
authors: Grippo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001132:Arm / Q000503:physiopathology*; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D017063:Outcome Assessment, Health Care; D010291:Paresis / Q000503:physiopathology / Q000534:rehabilitation; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D020521:Stroke / Q000503:physiopathology*; D000071939:Stroke Rehabilitation; D050781:Transcranial Magnetic Stimulation