Synthetic lethality--a new direction in cancer-drug development.
Iglehart
J Dirk
JD
Silver
Daniel P
DP
D004249:DNA Damage; D004260:DNA Repair; D015195:Drug Design; D004354:Drug Screening Assays, Antitumor; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D005804:Genes, Lethal; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics; D010793:Phthalazines / Q000627:therapeutic use; D010879:Piperazines / Q000627:therapeutic use; D000067856:Poly(ADP-ribose) Polymerase Inhibitors
D010793:Phthalazines; D010879:Piperazines; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; C531550:olaparib