title: Studies on the constituents of whole plants of Youngia japonica.
abstract: Two new guaiane-type sesquiterpene (1, 2), 2 new phenylpropanoid derivatives (3, 4), and 5-oxo-11-hydroxy-8(Z)-undecenoic acid 11-O-glucoside (5), together with 17 known compounds have been isolated from the whole plants of Youngia japonica (L.) Dc., which have been known to be used as folk medicines to treat people suffering from atopy. The guaiane-type sesquiterpene, grosheimin (17) exhibited strong antiallergic and antioxidant activities.
authors: Faculty of Medical and Pharmaceutical Sciences, Kumamoto University.
authors: Emiko
authors: E
authors: Yae
authors: Shoji
authors: S
authors: Yahara
authors: Mona
authors: M
authors: El-Aasr
authors: Tsuyoshi
authors: T
authors: Ikeda
authors: Hitoshi
authors: H
authors: Yoshimitsu
authors: Chikako
authors: C
authors: Masuoka
authors: Masateru
authors: M
authors: Ono
authors: Izumi
authors: I
authors: Hide
authors: Yoshihiro
authors: Y
authors: Nakata
authors: Toshihiro
authors: T
authors: Nohara
mesh_terms: D018926:Anti-Allergic Agents / Q000737:chemistry / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology; D008967:Molecular Biology; D015394:Molecular Structure; D020005:Propanols / Q000737:chemistry* / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: C542451:5-oxo-11-hydroxy-8(Z)-undecenoic acid 11-O-glucoside; D018926:Anti-Allergic Agents; D005960:Glucosides; D020005:Propanols; D012717:Sesquiterpenes