title: Reflections on miR-ing effects in metastasis.
abstract: In a recent issue of Cell, Valastyan et al. demonstrate that miR-31 can regulate multiple steps in the metastatic cascade independent of confounding effects on primary tumor development. These data have potential to provide biomarkers for prognosis and novel targets for intervention in this most lethal aspect of malignancy.
authors: Department of Pathology, University of California at San Francisco, San Francisco, CA 94143, USA.
authors: Nancy
authors: N
authors: Dumont
authors: Thea D
authors: TD
authors: Tlsty
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D001940:Breast / Q000502:physiology; D001943:Breast Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D045744:Cell Line, Tumor; D005260:Female; D006801:Humans; D051379:Mice; D035683:MicroRNAs / Q000235:genetics*; D009362:Neoplasm Metastasis / Q000235:genetics*; D016019:Survival Analysis
chemical_list: C534612:MIRN31 microRNA, human; D035683:MicroRNAs