Does dilation and curettage versus expectant management for spontaneous abortion in patients undergoing in vitro fertilization affect subsequent endometrial development?
In in vitro fertilization patients, treatment of spontaneous abortion with dilation and curettage (D&C) versus expectant management has no long-term effect on subsequent endometrial development, as measured by change in endometrial thickness. A transient reduction in endometrial thickness was found within the first 6 months after D&C, which is a novel finding, but it is likely to have little or no effect on pregnancy rates given the small absolute effect on endometrial thickness.
Moon
Kimberly S
KS
Department of Obstetrics and Gynecology, Georgetown University Hospital, Washington, DC, USA.
Richter
Kevin S
KS
Levy
Michael J
MJ
Widra
Eric A
EA
D000022:Abortion, Spontaneous / Q000453:epidemiology / Q000473:pathology / Q000534:rehabilitation* / Q000628:therapy*; D000328:Adult; D004107:Dilatation and Curettage / Q000009:adverse effects* / Q000379:methods / Q000706:statistics & numerical data; D010064:Embryo Implantation / Q000502:physiology; D004717:Endometrium / Q000254:growth & development* / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D009929:Organ Size; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D002581:Uterine Cervical Incompetence / Q000453:epidemiology / Q000209:etiology