Associated factors in children with chronic cough.
BACKGROUND
Children presenting with chronic cough are common to the primary care physicians, but data on the etiology are scant.


METHODS
We evaluated 40 children (age range, 5 to 12 years) with chronic cough (> 8 weeks duration) with no obvious cause who were referred by their primary care physicians. All patients underwent an extensive multispecialty workup that included pulmonary, GI, allergy, immunology, and otorhinolaryngology testing. Response to treatment was quantified pretreatment and 8 weeks after treatment by using a visual analog scale.


RESULTS
Positive diagnostic test results were noted for gastroesophageal reflux disease (27.5%), allergy (22.5%), asthma (12.5%), infection (5%), aspiration (2.5%), and multiple etiologies (20%). Appropriate treatment for these factors resulted in a significant improvement in cough.


CONCLUSIONS
Reflux, allergy, and asthma accounted for > 80% of the likely etiologic factors of chronic cough in children and responded to appropriate treatment.
Khoshoo
Vikram
V
West Jefferson Medical Center, New Orleans, LA. Electronic address: vkhoshoo@sbcglobal.net.
Edell
Dean
D
West Jefferson Medical Center, New Orleans, LA.
Mohnot
Sopan
S
Tulane University, New Orleans, LA.
Haydel
Robert
R
West Jefferson Medical Center, New Orleans, LA.
Saturno
Emilio
E
West Jefferson Medical Center, New Orleans, LA.
Kobernick
Aaron
A
Tulane University Medical Center, New Orleans, LA.
D001249:Asthma / Q000150:complications / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003371:Cough / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000628:therapy; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000628:therapy; D007239:Infections / Q000150:complications; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors