Antibacterial activity in vitro of Thymus capitatus from Jordan.
This study was carried out to evaluate the antibacterial activity of aqueous and organic extracts of Thymus capitatus L. (Lamiaceae) leaves and stems. Dried ground powder leaves and stems were extracted with water (aqueous extracts), ethanol, dichloromethane and hexane (Soxhlet extracts). The antibacterial activity of these extracts was evaluated against bacteria using disc diffusion method. The result obtained showed that the leaves had stronger antibacterial activity than the stems extracts. The ethanolic extract had the highest yield products and the high antibacterial activity than all other solvents. The results suggest that essential oil as non-polar organic compounds could be the main active compounds in this plant. Therefore the antibacterial activity of leaves ethanol extracts (LEE) was compared with essential oils leaves extracts (LEO) of T. capitatus. The LEO showed greater antibacterial activity than LEE. The LEO showed a broad spectrum of antibacterial activity and the Pseudomonas aeruginosa was the most sensitive bacteria.
Qaralleh
Haitham N
HN
Department of Biomedical Science, International Islamic University Malaysia, 25200 Kuantan Pahang Darul Makmur, Malaysia. haithym2006@yahoo.com
Abboud
Muayad M
MM
Khleifat
Khaled M
KM
Tarawneh
Khaled A
KA
Althunibat
Osama Y
OY
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D015169:Colony Count, Microbial; D021902:Enterobacter aerogenes / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007597:Jordan; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D046930:Thymus Plant / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010936:Plant Extracts