Pyridine N-oxides as ligands in Cu-catalyzed N-arylation of imidazoles in water.
N-arylation of imidazoles with aryl halides catalyzed by a combination of copper(II) sulfate and 1,2-bis(2-pyridyl)-ethane-N,N'-dioxide in water afforded up to 95% yield.
Liang
Lei
L
Institute of Homogeneous Catalysis, College of Chemistry, Sichuan University, Chengdu 610064, China.
Li
Zhengkai
Z
Zhou
Xiangge
X
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D019327:Copper Sulfate / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007093:Imidazoles / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D007093:Imidazoles; D007462:Iodobenzenes; D008024:Ligands; D011725:Pyridines; D014867:Water; D003300:Copper; C013229:pyridine N-oxide; C031905:iodobenzene; D019327:Copper Sulfate