[Relationship between characteristic geometry and risk of rupture in cerebral saccular aneurysm].
OBJECTIVE
To explore the relationship between the characteristic geometry and the risk of rupture in cerebral saccular aneurysm.


METHODS
The clinical features of 473 cerebral saccular aneurysm patients with complete materials of cerebral angiography, 426 with ruptured aneurysm and 47 with unruptured aneurysm, were analyzed retrospectively. The relation of depth, neck width, and aspect ratio (AR) of aneurysms to the risk of rupture were analyzed.


RESULTS
The mean depth, neck width, and the AR of the patients with ruptured aneurysm were (5.9+/-3.0) mm, (3.0+/-1.2) mm, and (2.1+/-0.9), all significantly lower than those of the unruptured aneurysm patients [(8.0+/-4.2) mm, (4.8+/-2.4) mm, and (1.7+/-0.6) respectively, all P<0.01].


CONCLUSIONS
AR is not correlated with the location of aneurysms, but reflects the geometrical and hemodynamic features of cerebral saccular aneurysms very well. High AR may be useful in predicting imminent aneurysmal rupture. But by now, no definitive AR level is accepted in discriminating between unruptured and ruptured aneurysms.
Song
Jian-ping
JP
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Mao
Ying
Y
Song
Dong-lei
DL
Leng
Bing
B
Gu
Yu-xiang
YX
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000209:etiology*; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012039:Regional Blood Flow; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult