title: Antiviral properties of glycyrrhizic acid and its semisynthetic derivatives.
abstract: Some natural triterpenes exert a definite antiviral activity on several human viruses. New synthetic derivatives of glycyrrhizic acid (GL) are even more active than the parental molecule. GL can alter the expression of viral genes involved in cell transformation, thus opening a new window for speculating on viral cancerogenesis.
authors: Sezione di Microbiologia, Dept. of STB, University of Cagliari, Via Porcell 4, 09124 Cagliari, Italy. rpompei@unica.it
authors: Raffaello
authors: R
authors: Pompei
authors: Samuela
authors: S
authors: Laconi
authors: Angela
authors: A
authors: Ingianni
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D015967:Gene Expression Regulation, Viral / Q000187:drug effects; D019695:Glycyrrhizic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D014780:Viruses / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development
chemical_list: D000998:Antiviral Agents; D019695:Glycyrrhizic Acid