Adnexal mass vascularity assessed by 3-dimensional power Doppler: does it add to the risk of malignancy index in prediction of ovarian malignancy?: four hundred-case study.
The Risk of Malignancy Index (RMI) is used for the prediction of ovarian malignancy. It includes menopausal status, carbohydrate antigen 125 serum levels, and ultrasound criteria. Three-dimensional power Doppler (3-DPD) is a reproducible investigation for assessment of tumor vascularity, classifying vascularity to avascular, parallel, and chaotic patterns. In this study; 3-DPD was added to RMI for prediction of malignancy in 400 cases of ovarian masses. Sensitivity of RMI for prediction of malignancy was 88%, with a cutoff value of 202.5 at 95% confidence interval. Sensitivity of 3-DPD for prediction of malignancy was 75%, adding 3-DPD to RMI increased its sensitivity to 99%. Considering the pilot nature of the study, further studies are needed to corroborate such findings.
Mansour
Ghada M
GM
Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt. gmansour@hotmail.com
El-Lamie
Ismail K
IK
El-Sayed
Helmy M
HM
Ibrahim
A M
AM
Laban
M
M
Abou-Louz
Sobhi K
SK
Abd Allah
M Y
MY
El-Mahallawi
M N
MN
El-Lamie
Khalil I
KI
Gad-Allah
Mohsen
M
D018262:Adenocarcinoma, Clear Cell / Q000098:blood supply; D002288:Adenocarcinoma, Mucinous / Q000098:blood supply; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018394:CA-125 Antigen / Q000097:blood*; D002291:Carcinoma, Papillary / Q000098:blood supply; D002648:Child; D018284:Cystadenocarcinoma, Serous / Q000098:blood supply; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008593:Menopause; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000097:blood* / Q000000981:diagnostic imaging*; D010051:Ovarian Neoplasms / Q000098:blood supply*; D011379:Prognosis; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler; D055815:Young Adult
D018394:CA-125 Antigen