A male patient with malignant lymphoma and thyroid papillary carcinoma after pediatric renal transplantation.
A 6-year-old boy received renal transplantation and was treated with methylprednisolone, cyclosporine A and mizoribine. He developed Epstein-Barr virus-associated malignant lymphoma at 10 years and thyroid papillary carcinoma at 20 years of age. Chemotherapy for the malignant lymphoma was done after withdrawal of cyclosporine A and mizoribine, and thyroidectomy was performed for thyroid carcinoma. He was well and his serum creatinine was 1.0 mg/dl at 22 years of age. To our knowledge, no pediatric renal transplant recipient who had thyroid carcinoma or two different types of tumor has been reported in Japan.
Motoyama
Osamu
O
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 654-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan. motoyan@basil.ocn.ne.jp
Takasu
Jiro
J
Kawamura
Takeshi
T
Aikawa
Atushi
A
Shigetomi
Yukari
Y
Nara
Chiharu
C
Ohara
Akira
A
Iitaka
Kikuo
K
Hasegawa
Akira
A
D002291:Carcinoma, Papillary / Q000188:drug therapy / Q000821:virology; D002648:Child; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008223:Lymphoma / Q000188:drug therapy / Q000821:virology*; D008297:Male; D013964:Thyroid Neoplasms / Q000821:virology; D013965:Thyroidectomy; D055815:Young Adult