Focused UV-B narrowband microphototherapy (Biopsorin). A new treatment for plaque psoriasis.
Skin irradiation with ultraviolet light B (UV-B) and in particular the emission peak at 311 nm represents an effective therapeutic regimen for psoriasis. Excessive tanning, photoaging, and skin cancerization do occur mainly in subjects with skin phototype I to III. The possibility of developing skin cancer is parallel to the skin surface area under treatment and to the overall irradiation dose. We report here on a new focused phototherapy method releasing UV-B with a peak at 311 nm, which consists in the selective irradiation of single psoriatic patches with a new device equipped with a special optic fiber. The treatment is effective, safe and well tolerated. Psoriasis Area and Severity Index 75 is achieved in 64% of patients after 12 sessions of treatment. The Physician Global Assessment evaluation significantly improves in all treated patients.
Lotti
Torello
T
University Unit of Dermatology, University of Florence School of Medicine, Florence, Italy. tlotti@unifi.it
Tripo
Lara
L
Grazzini
Marta
M
Krysenka
Alena
A
Buggiani
Gionata
G
De Giorgi
Vincenzo
V
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055100:Optical Fibers; D011565:Psoriasis / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012720:Severity of Illness Index; D014467:Ultraviolet Therapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*