Common factors regulating patterning of the nervous and vascular systems.
The vascular and the nervous systems of vertebrates share many features with similar and often overlapping anatomy. The parallels between these two systems extend to the molecular level, where recent work has identified ever-increasing similarities between the molecular mechanisms employed in the specification, differentiation, and patterning of both systems. This review discusses some of the most recent literature on this subject, with particular emphasis on the roles that the Ephrin, Semaphorin, Netrin, and Slit signaling pathways play in vascular development.
Melani
Mariana
M
Program in Genomics of Differentiation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Weinstein
Brant M
BM
D000818:Animals; D001808:Blood Vessels / Q000196:embryology* / Q000378:metabolism; D019521:Body Patterning; D002319:Cardiovascular System / Q000196:embryology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism; D009420:Nervous System / Q000196:embryology* / Q000378:metabolism; D014714:Vertebrates / Q000196:embryology
D036341:Intercellular Signaling Peptides and Proteins