EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma.
BACKGROUND
Approximately 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma.


METHODS
We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark.


RESULTS
The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations.


CONCLUSIONS
The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit.
Boysen
T
T
Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark.
Mohammadi
M
M
Melbye
M
M
Hamilton-Dutoit
S
S
Vainer
B
B
Hansen
A V
AV
Wohlfahrt
J
J
Friborg
J
J
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000821:virology*; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000821:virology*