title: Anxiety sensitivity, acute nicotine withdrawal symptoms, and anxious and fearful responding to bodily sensations: a laboratory test.
abstract: The present investigation examined the moderating role of anxiety sensitivity (AS) in regard to the relation between acute nicotine withdrawal and anxious and fearful responding to a 10% carbon dioxide-enriched air (CO2) procedure. Ninety daily smokers (35 women; M(age) = 28.87, SD = 12.12) were assigned randomly to one of two groups (12-hr nicotine deprivation or smoking "as usual") and subsequently underwent a 10% CO2 provocation challenge. Partially consistent with prediction, results indicated that the AS by nicotine withdrawal (group status) interaction was significantly predictive of peri-challenge anxiety ratings (anxiety during the challenge), but not skin conductance reactivity. Findings are discussed in the context of the role of AS in amplifying smoking-based fear responses to bodily sensations.
authors: Alpert Medical School of Brown University.
authors: Anka A
authors: AA
authors: Vujanovic
authors: University of Vermont.
authors: Michael J
authors: MJ
authors: Zvolensky
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000523:psychology*; D001944:Breath Tests; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000009:adverse effects*; D012677:Sensation / Q000502:physiology*; D012907:Smoking / Q000523:psychology*; D013375:Substance Withdrawal Syndrome / Q000523:psychology*
chemical_list: D009538:Nicotine