title: Natural frequency of a gas bubble in a tube: experimental and simulation results.
abstract: Use of ultrasonically excited microbubbles within blood vessels has been proposed for a variety of clinical applications. In this paper, an axisymmetric coupled boundary element and finite element code and experiments have been used to investigate the effects of a surrounding tube on a bubble's response to acoustic excitation. A balloon model allowed measurement of spherical gas bubble response. Resonance frequencies match one-dimensional cylindrical model predictions for a bubble well within a rigid tube but deviate for a bubble near the tube end. Simulations also predict bubble translation along the tube axis and aspherical oscillations at higher amplitudes.
authors: Mechanical Engineering, University of Rochester, Rochester, New York 14627, USA.
authors: Neo W
authors: NW
authors: Jang
authors: Sheryl M
authors: SM
authors: Gracewski
authors: Ben
authors: B
authors: Abrahamsen
authors: Travis
authors: T
authors: Buttaccio
authors: Robert
authors: R
authors: Halm
authors: Diane
authors: D
authors: Dalecki
mesh_terms: D000162:Acoustics; D001808:Blood Vessels / Q000502:physiology; D003198:Computer Simulation; D005740:Gases; D045423:Microbubbles; D008962:Models, Theoretical; D009038:Motion; D014732:Vibration
chemical_list: D005740:Gases