Centrosomes: CNN's broadcast reaches the cleavage furrow.
Centrosomin (CNN), a core Drosophila centrosome protein, interacts with the newly identified protein Centrocortin to promote cleavage furrow formation in the early embryo. Significantly, this activity is distinct from CNN's well-established role in centrosome-based microtubule organization.
Sullivan
William
W
Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95066, USA. sullivan@biology.ucsc.edu
D000818:Animals; D002455:Cell Division / Q000502:physiology*; D018385:Centrosome / Q000378:metabolism*; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000166:cytology / Q000196:embryology; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000378:metabolism; D018398:Homeodomain Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism
D029721:Drosophila Proteins; D018398:Homeodomain Proteins; C098130:cnn protein, Drosophila