title: N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with arylsulfonyl indoles.
abstract: 3-(1-Arylsulfonylalkyl)indoles as electrophiles in the N-heterocyclic carbene-catalyzed umpolung reaction of aldehydes were realized for the first time. This intermolecular Stetter-type reaction features the commercially available catalyst and mild reaction conditions, providing alpha-(3-indolyl) ketone derivatives in high yields for a wide range of substrates.
authors: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
authors: Yi
authors: Y
authors: Li
authors: Fu-Qiang
authors: FQ
authors: Shi
authors: Qing-Li
authors: QL
authors: He
authors: Shu-Li
authors: SL
authors: You