ABC efflux pump-based resistance to chemotherapy drugs.
Eckford
Paul D W
PD
Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
Sharom
Frances J
FJ
D018528:ATP-Binding Cassette Transporters / Q000737:chemistry* / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism / Q000627:therapeutic use; D001667:Binding, Competitive; D019008:Drug Resistance, Neoplasm; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D017434:Protein Structure, Tertiary; D013379:Substrate Specificity
D018528:ATP-Binding Cassette Transporters; D000970:Antineoplastic Agents