Adhesions following surgery: pathogenesis and current experience with adhesion barriers.
Postoperative adhesions are a serious consequence of any type of intra-abdominal surgery and can result in infertility, pain, or bowel obstruction. Unfortunately, the paradox with adhesiolysis is that surgery performed to remove adhesions often results in further adhesion formation, so the problem persists and symptoms return and complications recur. Laparoscopic surgery with adherence to microsurgical techniques such as minimal tissue handling, rigorous attention to hemostasis, and copious irrigation was initially thought to minimize adhesion formation but such hopes have not been validated by clinical studies.
Sutton
Christopher
C
Gynecological Surgery, University of Surrey, Guildford, UK.
D000336:Aerosols / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D008567:Membranes, Artificial; D000267:Tissue Adhesions / Q000209:etiology* / Q000517:prevention & control*; D016896:Treatment Outcome
D000336:Aerosols; D008567:Membranes, Artificial