Sphaeroane and neodolabellane diterpenes from the red alga Sphaerococcus coronopifolius.
Investigation of minor metabolites in the extracts of the red alga Sphaerococcus coronopifolius collected from the rocky coasts of Corfu Island in the Ionian Sea yielded two new diterpene alcohols, sphaerollanes I, and II (1, 2) featuring neodolabellane skeletons, and the new sphaeroane diterpene alcohol 16-hydroxy-9S*-acetoxy-8-epi-isosphaerodiene-2 (3), along with two previously reported metabolites 4, 5. The structures of the new natural products, as well as their relative stereochemistry, were elucidated on the basis of extensive spectral analysis, including 2D-NMR experiments.
Smyrniotopoulos
Vangelis
V
Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece. esmiriniot@geol.uoa.gr
Vagias
Constantinos
C
Roussis
Vassilios
V
D000438:Alcohols / Q000737:chemistry* / Q000302:isolation & purification; D001688:Biological Products / Q000737:chemistry* / Q000302:isolation & purification; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D009792:Oceans and Seas; D000461:Rhodophyta / Q000737:chemistry*
D000438:Alcohols; D001688:Biological Products; D004224:Diterpenes