Advances in marine microbial symbionts in the china sea and related pharmaceutical metabolites.
Marine animals and plants such as sponges, sea squirts, corals, worms and algae host diverse and abundant symbiotic microorganisms. Marine microbial symbionts are possible the true producers or take part in the biosynthesis of some bioactive marine natural products isolated from the marine organism hosts. Investigation of the pharmaceutical metabolites may reveal the biosynthesis mechanisms of related natural products and solve the current problem of supply limitation in marine drug development. This paper reviews the advances in diversity revelation, biological activity and related pharmaceutical metabolites, and functional genes of marine microbial symbionts from the China Sea.
Li
Zhiyong
Z
Laboratory of Marine Biotechnology, School of Life Sciences and Biotechnology and Key Laboratory of Microbial Metabolism, Ministry of Education, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P.R. China. zyli@sjtu.edu.cn
D000818:Animals; D001419:Bacteria / Q000235:genetics / Q000378:metabolism; D018407:Bacterial Physiological Phenomena; D001688:Biological Products / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D007448:Invertebrates / Q000382:microbiology*; D008386:Marine Biology; D009792:Oceans and Seas; D004364:Pharmaceutical Preparations / Q000302:isolation & purification; D013559:Symbiosis
D001688:Biological Products; D004364:Pharmaceutical Preparations