title: Effects of 915 MHz electromagnetic-field radiation in TEM cell on the blood-brain barrier and neurons in the rat brain.
abstract: The aim of this study was to determine whether albumin leakage and dark neurons were present in rat brains 14 and 50 days after a single 2-h exposure to a 915 MHz electromagnetic field, as reported by Salford et al. (Environ. Health Perspect. 111, 881-883, 203). Sixty-four male F344 rats (12 weeks old) were exposed to a 915 MHz electromagnetic field at whole-body average specific absorption rates of 0, 0.02, 0.2 and 2.0 W/kg in TEM cells for 2 h, following the protocol reported by Salford et al. The brains were examined histologically and immunohistochemically. No albumin immunoreactivity was observed in the exposed groups. In addition, dark neurons, assessed using hematoxylin and eosin staining, were rarely present, with no statistically significant difference between exposed and sham-exposed animals. This study thus failed to confirm the results of Salford et al.
authors: Department of Environmental Health, National Institute of Public Health, 2-3-6 Minami, Wako-shi, Saitama 351-0197, Japan. hiroshi.masuda@ims-bordeaux.fr
authors: Hiroshi
authors: H
authors: Masuda
authors: Akira
authors: A
authors: Ushiyama
authors: Miyuki
authors: M
authors: Takahashi
authors: Jianqing
authors: J
authors: Wang
authors: Osamu
authors: O
authors: Fujiwara
authors: Takashi
authors: T
authors: Hikage
authors: Toshio
authors: T
authors: Nojima
authors: Koji
authors: K
authors: Fujita
authors: Motoshige
authors: M
authors: Kudo
authors: Chiyoji
authors: C
authors: Ohkubo
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001812:Blood-Brain Barrier / Q000473:pathology / Q000528:radiation effects*; D001835:Body Weight / Q000528:radiation effects; D001921:Brain / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects*; D002199:Capillary Permeability / Q000528:radiation effects; D004574:Electromagnetic Fields; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000528:radiation effects*; D011829:Radiation Dosage; D051381:Rats; D011916:Rats, Inbred F344; D012709:Serum Albumin / Q000378:metabolism
chemical_list: D012709:Serum Albumin