title: A general copper-catalyzed coupling of azoles with vinyl bromides.
abstract: A copper-catalyzed methodology for the coupling of vinyl bromides with azoles has been developed. This protocol uses a combination of 10 mol % of copper iodide and 20 mol % of ethylenediamine as catalyst. The reaction proceeds with various azoles and vinyl bromides, and the double bond geometry of vinyl bromides is retained under the reaction conditions.
authors: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084 China.
authors: Qian
authors: Q
authors: Liao
authors: Yuxing
authors: Y
authors: Wang
authors: Liyun
authors: L
authors: Zhang
authors: Chanjuan
authors: C
authors: Xi
mesh_terms: D001393:Azoles / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005029:Ethylenediamines / Q000737:chemistry; D008024:Ligands; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D001393:Azoles; D005029:Ethylenediamines; D008024:Ligands; D014753:Vinyl Compounds; C031234:ethylenediamine; D003300:Copper; C003763:vinyl bromide