title: Pharmacological and lifestyle factors modulating serum paraoxonase-1 activity.
abstract: Paraoxonase-1 is a lactonase and an esterase and it plays a protective role in toxicity as well as in diseases involving oxidative stress. Recently, insights into how it may be modulated by environmental factors have acquired clinical relevance. This article reviews the state-of-the-art evidence regarding PON1 modulation by pharmacological products as well as nutritional and lifestyle factors.
authors: Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, C. Sant Joan s/n, 43201 Reus, Catalunya, Spain. jcamps@grupsagessa.cat
authors: Jordi
authors: J
authors: Camps
authors: Judit
authors: J
authors: Marsillach
authors: Jorge
authors: J
authors: Joven
mesh_terms: D043303:Aryldialkylphosphatase / Q000097:blood* / Q000737:chemistry; D004032:Diet; D006801:Humans; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000494:pharmacology*; D008019:Life Style; D008958:Models, Molecular; D018384:Oxidative Stress; D011487:Protein Conformation
chemical_list: D000960:Hypolipidemic Agents; D043303:Aryldialkylphosphatase