title: Synthetic studies on vincorine: access to the 3a,8a-dialkyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole skeleton.
abstract: Synthetic studies on vincorine are described; the conversion of 3-aminoethyl-3-alkyloxindoles to 3a,8a-dialkyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indoles has been achieved through an addition-cyclization sequence, and a fully functionalized key intermediate was constructed with this method.
authors: WPI Advanced Institute for Materials Research, Tohoku University, Japan.
authors: Yoshizumi
authors: Y
authors: Yasui
authors: Tomoyo
authors: T
authors: Kinugawa
authors: Yoshiji
authors: Y
authors: Takemoto
mesh_terms: D007211:Indoles / Q000737:chemistry*; D014748:Vinca Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007211:Indoles; D014748:Vinca Alkaloids; C543267:vincorine