title: Sclerosing nevus with pseudomelanomatous features (nevus with regression-like fibrosis): clinical and dermoscopic features of a recently characterized histopathologic entity.
abstract: BACKGROUND
  Sclerosing nevi with pseudomelanomatous features or, else, nevi with regression-like fibrosis (NRLF) are histopathologic simulators of regressing melanoma.
  
  
  OBJECTIVE
  We aimed at evaluating the clinical features in a series of NRLF.
  
  
  METHODS
  Dermoscopic images of NRLF were re-evaluated according to the amount of regression, the presence of white/blue areas and the 7-point checklist.
  
  
  RESULTS
  Forty-six lesions from 44 patients (M:F = 3.4:1; mean age: 42 years) were evaluated. Thirty-seven lesions were excised from the back, mostly from the scapular area. All the lesions were dermoscopically atypical, with large amounts of regression (>10% in 43 cases) and with coexistence of white and blue areas (41 cases). According to the 7-point checklist, 25 lesions were labeled as benign, probably because regression obscured other dermoscopic features of atypia.
  
  
  CONCLUSIONS
  NRLF are mostly found in the convex area of the back. A better recognition of their clinicopathologic features can allow a more conservative management.
authors: Department of Oncology, Pathologic Anatomy Unit, Gaetano Rummo General Hospital, Benevento, Italy.
authors: Gerardo
authors: G
authors: Ferrara
authors: Caterina M
authors: CM
authors: Giorgio
authors: Iris
authors: I
authors: Zalaudek
authors: Paolo
authors: P
authors: Broganelli
authors: Giovanni
authors: G
authors: Pellacani
authors: Carlo
authors: C
authors: Tomasini
authors: Giuseppe
authors: G
authors: Argenziano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D046169:Dermoscopy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005355:Fibrosis / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D009506:Nevus / Q000473:pathology*; D012598:Sclerosis / Q000473:pathology; D055815:Young Adult