Oxindole synthesis by direct C-H, Ar-H coupling.
A novel copper(II)-mediated route for the conversion of anilides into 3,3-disubstituted-oxindoles is described which proceeds via a formal C-H, Ar-H coupling process.
Perry
Alexis
A
Department of Chemistry, University of York, Heslington, York, UK YO10 5DD.
Taylor
Richard J K
RJ
D000478:Alkylation; D001554:Benzene / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D006859:Hydrogen / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis*; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry
D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D010165:Palladium; D002244:Carbon; D003300:Copper; D006859:Hydrogen; D001554:Benzene