[Association of polymorphism for porcine BF gene with reproductive traits and placental efficiency in Large White].
Taking BF gene as one of the candidate genes influencing on reproductive traits in present study, this study used PCR-RFLP analyzised the polymorphism of intron 1 of BF gene in Large White sows. A single nucleotide polymorphism (SNP) named as BF-intron 1-C79T was detected. And the three genotypes of CC, CT, TT got fitted Hardy-Weinberg equilibrium with chi2-fitness test. An association analysis was tested between the genetic polymorphism at intron 1 and total number born (TNB), number born alive (NBA), born weight (BW) and placental efficiency (PE) respectively. It showed that, at first parity, the TNB, NBA, BW and PE with CC genotype were higher than those with CT genotype but not significant (P>0.05). Meanwhile, in multiparous sow population, the TNB, NBA and PE with CC genotype were significantly more than those with TT genotype (P<0.05), with increase of 3.45, 3.92, and 23.80%, respectively. Thus BF-intron 1-C79T is suggested to be a potential genetic marker for the breeding on the reproductive traits and placental efficiency.
Chen
Lai-Hua
LH
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. C.laihua@gmail.com
Wang
Li-Xian
LX
Ji
Yue-Guang
YG
Zhang
Long-Chao
LC
Yan
Hua
H
D000818:Animals; D011415:Complement Factor B / Q000235:genetics* / Q000502:physiology; D005260:Female; D005838:Genotype; D008969:Molecular Sequence Data; D010298:Parity; D010641:Phenotype; D010920:Placenta / Q000502:physiology; D010925:Placental Function Tests; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide; D011247:Pregnancy; D012098:Reproduction / Q000235:genetics*; D012741:Sexual Maturation; D034421:Sus scrofa; D013552:Swine
D011415:Complement Factor B