Intraductal papillary mucinous neoplasms of the pancreas: correlation of helical CT features with pathologic findings.
OBJECTIVE
To evaluate the CT features of intraductal papillary mucinous neoplasms of the pancreas (IPMNs), and to compare with pathological findings in order to identify CT features that can be helpful in differentiating benign IPMNs from malignant IPMNs.


METHODS
The CT findings in 25 patients were reviewed for tumor location, tumor type, dilatation of the main pancreatic duct (MPD), MPD involvement, mural node or solid attenuating component, tumor size in branch duct or mixed duct type, dilatation of common bile duct (CBD) and invasion of surrounding structures. The data was subjected to Chi-Square Tests or Fisher's Exact Test using SPSS13.0 software with p value<0.05 indicating significant statistical difference.


RESULTS
Presence of mural node or solid enhancing component, size of mural node or solid enhancing component ≥7mm, dilatation of CBD was more common in malignant IPMNs (p<0.05). None of tumor location, tumor type, dilatation of MPD, MPD involvement, tumor size, and invasion of surrounding structures was statistically significant in differentiating benign from malignant IPMNs.


CONCLUSIONS
CT features suggestive of malignant or invasive IPMNs include presence of mural node or solid enhancing component, size of mural node or solid enhancing component ≥7mm, and dilatation of CBD.
Liu
Yu
Y
The Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China.
Lin
Xiaozhu
X
Upadhyaya
Manavendra
M
Song
Qi
Q
Chen
Kemin
K
D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging* / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D021441:Carcinoma, Pancreatic Ductal / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D036542:Tomography, Spiral Computed / Q000379:methods*