title: Distribution of endogenous retroviruses in crocodilians.
abstract: Knowledge of endogenous retroviruses (ERVs) in crocodilians (Crocodylia) is limited, and their distribution among extant species is unclear. Here we analyzed the phylogenetic relationships of these retroelements in 20 species of crocodilians by studying the pro-pol gene. The results showed that crocodilian ERVs (CERVs) cluster into two major clades (CERV 1 and CERV 2). CERV 1 clustered as a sister group of the genus Gammaretrovirus, while CERV 2 clustered distantly with respect to all known ERVs. Interestingly, CERV 1 was found only in crocodiles (Crocodylidae). The data generated here could assist future studies aimed at identifying orthologous and paralogous ERVs among crocodilians.
authors: Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, RMC Gunn Building, University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Weerachai
authors: W
authors: Jaratlerdsiri
authors: Clara J
authors: CJ
authors: Rodríguez-Zárate
authors: Sally R
authors: SR
authors: Isberg
authors: Chandramaya Siska
authors: CS
authors: Damayanti
authors: Lee G
authors: LG
authors: Miles
authors: Nantarika
authors: N
authors: Chansue
authors: Chris
authors: C
authors: Moran
authors: Lorna
authors: L
authors: Melville
authors: Jaime
authors: J
authors: Gongora
mesh_terms: D000465:Algorithms; D000489:Alligators and Crocodiles; D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods; D020077:Endogenous Retroviruses / Q000235:genetics* / Q000378:metabolism*; D019143:Evolution, Molecular; D010802:Phylogeny; D018626:Retroelements
chemical_list: D000596:Amino Acids; D018626:Retroelements