[Cataract extraction and blue light--impact on the retina].
This review focuses on the scientific background for the use of "yellow artificial lenses". We will address the fact that numerous basic scientific publications point to a rationale for this practice although it is often difficult to derive clear-cut evidence from clinical epidemiological studies for the preventive use of yellow artificial lenses. In the first part we refer to studies showing that especially the shortwave part of the visible spectrum of light can be harmful for the retina and optic nerve. For this, we have screened the literature for the major sources of radical production and for the targets of oxidative stress after impingement of "blue light" on the retina. Furthermore, we can show that many studies in cell and molecular biology, animal experiments and first clinical trials point to a preferential use of yellow-tinted lenses especially in the elderly and AMD patients.
Engelmann
K
K
Augenklinik, Klinikum Chemnitz gGmbH. k.engelmann@skc.de
Funk
R H
RH
D000368:Aged; D000818:Animals; D001813:Blood-Retinal Barrier / Q000528:radiation effects; D019317:Evidence-Based Medicine; D006801:Humans; D007910:Lenses, Intraocular; D008027:Light / Q000009:adverse effects*; D008266:Macula Lutea / Q000528:radiation effects; D008268:Macular Degeneration / Q000209:etiology / Q000517:prevention & control; D018384:Oxidative Stress / Q000528:radiation effects; D010857:Pigment Epithelium of Eye / Q000528:radiation effects; D017797:Prosthesis Coloring; D012160:Retina / Q000528:radiation effects*; D012171:Retinal Vessels / Q000528:radiation effects; D012307:Risk Factors