title: Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites.
abstract: Primary acute myeloid leukemia (AML) with extramedullary infiltration (EMI) in multiple sites is rare. Herein, we describe a case of infant AML with EMI in multiple sites. She had dyspnea and hypofibrinogenemia at diagnosis, and systemic computed tomography revealed EMI in the orbit, gingiva, bronchial pathway, and urinary tract. Bone marrow examination confirmed the diagnosis of AML with t(1;10)(p34;p15). No case of AML with t(1;10)(p34;p15) has been reported in the literature. At the present time, she remains free of disease 12 months after bone marrow transplantation (BMT) in the second complete remission.
authors: Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, Japan.
authors: Michinori
authors: M
authors: Funato
authors: Toshiyuki
authors: T
authors: Fukao
authors: Hideo
authors: H
authors: Sasai
authors: Tomohiro
authors: T
authors: Hori
authors: Daisuke
authors: D
authors: Terazawa
authors: Michio
authors: M
authors: Ozeki
authors: Kenji
authors: K
authors: Orii
authors: Takahide
authors: T
authors: Teramoto
authors: Hideo
authors: H
authors: Kaneko
authors: Naomi
authors: N
authors: Kondo
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007223:Infant; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics*; D017254:Leukemic Infiltration / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics*; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic