Theta-Modulated Input Reduces Intrinsic Gamma Oscillations in a Hippocampal Model.
Introducing theta-modulated input into a minimal model of the CA3 region of the hippocampus has significant effects on gamma oscillations. In the absence of theta-modulated input, the gamma oscillations are robust across a range of parameters. Introducing theta-modulated input weakens the gamma oscillations to a power more consistent with power spectra acquired from laboratory animals. With these changes, simulations of the hippocampal model are able to reproduce hippocampal power spectra measured in awake mice.
Hocking
Ashlie B
AB
Department of Neurosurgery, University of Virginia, Charlottesville, VA.
Levy
William B
WB