Synthesis of new tripodal Hantzsch 1,4-dihydropyridines under solvent-free condition and their conversion to the corresponding tripodal pyridines.
A mixture of β-ketoester and tri-aldehydes in the presence of ammonium fluoride was converted to their corresponding tripodal 1,4-dihydropyridines under solvent-free condition with good yields. The obtained tripodal 1,4-dihydropyridines were also aromatized with oxone(®)/NaNO(2)/wet SiO(2) system under mild and heterogeneous conditions quantitatively.
Zolfigol
Mohammad Ali
MA
Faculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838683, Iran. zolfi@basu.ac.ir
Kolvari
Eskandar
E
Abdoli
Abbas
A
Shiri
Morteza
M
D002384:Catalysis; D003500:Cyclization; D004095:Dihydropyridines / Q000737:chemistry*; D008954:Models, Biological; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents; D013237:Stereoisomerism
D004095:Dihydropyridines; D011725:Pyridines; D012997:Solvents; C038806:1,4-dihydropyridine