title: [Clinicopathologic analyses of non-compaction of ventricular myocardium].
abstract: OBJECTIVE
  To investigate the clinicopathologic manifestations of non-compaction of ventricular myocardium (NVM).
  
  
  METHODS
  Clinical data, electrocardiograms, echocardiography images and pathologic changes were studied in five cases of non-compaction of ventricular myocardium.
  
  
  RESULTS
  The patient's ages ranged from 29 to 57 years old, all were males. Abnormal electrocardiograms were obtained in all of the 5 cases. Among them, 3 were diagnosed using echocardiography. Histopathologic examination showed that there were abnormally coarse muscle trabeculation and deep recesses, interlacing in arrangement, over the inner wall of the heart chambers. The compacted myocardium became thinning down gradually from the base to the apex of the heart. The non-compacted myocardium bundles locating close to the endocardium were coarse and orderless in arrangement, nuclei were irregular and abnormal, nevertheless, the arrangement and appearance of the muscle bundles near by the pericardium part were essentially normal and the cell nuclei were evenly distributed.
  
  
  CONCLUSIONS
  There are no specific clinical manifestations obtained in patients with non-compaction of ventricular myocardium, however, the pathologic changes are characteristic and a clinical diagnosis can be made by using echocardiography.
authors: Department of Pathology, Affiliated Anzhen Hospital, Capital Medical University, Beijing 100029, China.
authors: Jian-feng
authors: JF
authors: Shang
authors: Dong
authors: D
authors: Chen
authors: Hui-xin
authors: HX
authors: Zhang
authors: Wei
authors: W
authors: Fang
authors: Ying
authors: Y
authors: Wu
authors: Lei
authors: L
authors: Xiao
authors: Guo-liang
authors: GL
authors: Lian
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000473:pathology; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D014463:Ultrasonography