Birch reductions at room temperature with alkali metals in silica gel (Na2K-SG(I)).
Alkali metals in silica gel (the Na(2)K-SG(I) reagent) cleanly effect Birch reductions of substrates with at least two or more aromatic rings. The reaction conditions are alcohol-free, ammonia-free, and achieve excellent yields and high selectivities at room temperature.
Nandi
Partha
P
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
Dye
James L
JL
Jackson
James E
JE