[Immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice].
OBJECTIVE
To explore the immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice.


METHODS
The immunosuppressive mouse model was established by using hydrocortisone. Huangqi Fuzhengtang and Yupingfeng San apozema were given to the mice intragastrically. The contents of hemolysin, IL-2, and INF-gamma in the mouse serum and the expression of CD3(+), CD4(+), and CD8(+) in the peripheral blood lymphocytes were measured.


RESULTS
Huangqi Fuzhengtang could obviously elevate the contents of hemolysin, IL-2, INF-gamma and the ratio of CD4(+) and CD8+, which was more effective than Yupingfeng San.


CONCLUSIONS
Huangqi Fuzhengtang could improve the immune function in the immunosuppressive mice.
Luo
Xiaoli
X
Department of Cardiology, Third Xiangya Hospital, Changsha 410013, China.
Yang
Kan
K
Sun
Ming
M
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006854:Hydrocortisone; D016867:Immunocompromised Host / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D011897:Random Allocation; D016176:T-Lymphocyte Subsets / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D006854:Hydrocortisone