Surface plasmon-coupled directional emission based on a conformational-switching signaling aptamer.
We have observed highly polarized and directional surface plasmon-coupled emission of a signaling aptamer due to the binding of a target thrombin with the aptamer, which induces conformational switching.
Xie
Tang-Tang
TT
Department of Chemistry, College of Chemistry and Chemical Engineering, The Key Laboratory of Analytical Sciences of the Ministry of Education, Xiamen University, Xiamen, Fujian 361005, China.
Liu
Qian
Q
Cai
Wei-Peng
WP
Chen
Zhe
Z
Li
Yao-Qun
YQ
D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D006046:Gold / Q000737:chemistry; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D013050:Spectrometry, Fluorescence; D020349:Surface Plasmon Resonance; D013499:Surface Properties; D013917:Thrombin / Q000378:metabolism / Q000494:pharmacology
D052157:Aptamers, Nucleotide; D006046:Gold; D013917:Thrombin