Recurrent dedifferentiated liposarcoma of mediastinum involving lung and pleura.
We report a case of primary recurrent mediastinal dedifferentiated liposarcoma with unusual long-term survival. A woman who complained of dyspnea showed on imaging features a bulky posterior mediastinal mass which was completely excised and initially misdiagnosed as an angiomyolipoma. She recurred 15 months later and histological examination showed a dedifferentiated liposarcoma. Resection was incomplete and the patient received adjuvant therapy. Eight years later a second recurrence occurred in the right pleura and lung. The patient died three months later.
Coulibaly
Bema
B
Department of Pathology, CHU Timone, 264 rue Saint Pierre 13385 Marseille Cedex 05, France. bema_coulibaly@yahoo.fr
Bouvier
Corinne
C
Payan
Marie Jose
MJ
Thomas
Pascal
P
D000328:Adult; D001706:Biopsy; D054337:Cell Dedifferentiation; D017024:Chemotherapy, Adjuvant; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008080:Liposarcoma / Q000556:secondary* / Q000628:therapy; D008175:Lung Neoplasms / Q000556:secondary* / Q000628:therapy; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000628:therapy; D009364:Neoplasm Recurrence, Local; D010997:Pleural Neoplasms / Q000556:secondary* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome