title: The peri-operative use of intra-articular local anesthetics: a review.
abstract: Acute and chronic pain are of major concern after orthopedic surgery. The increasing trend toward day case surgery induced the development of different techniques in postoperative pain control. One commonly used strategy in pain management after knee and shoulder joint surgery is the intra-articular (IA) use of local anesthetics (LA). Recent attention has been drawn to the possible toxicity on chondrocytes of local anesthetics. The aim of this manuscript is to evaluate and compare through literature review the existing evidence on the clinical use and possible adverse effects of intra-articular injection of local anesthetics peri-operatively.
authors: Department of Anesthesiology, University Hospital Gent, Belgium.
authors: R J
authors: RJ
authors: Ballieul
authors: T F
authors: TF
authors: Jacobs
authors: S
authors: S
authors: Herregods
authors: P
authors: P
authors: Van Sint Jan
authors: B
authors: B
authors: Wyler
authors: H
authors: H
authors: Vereecke
authors: F
authors: F
authors: Almqvist
authors: L
authors: L
authors: Herregods
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000009:adverse effects; D001182:Arthroscopy; D002356:Cartilage / Q000187:drug effects; D006801:Humans; D007270:Injections, Intra-Articular; D007717:Knee / Q000601:surgery; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000779:Anesthetics, Local