Use of biomaterials with or without platelet-rich plasma in postextraction sites: a microscopic study in dogs.
OBJECTIVE
Sites that will receive dental implants need to be quantitatively and qualitatively suitable for this therapy. The treatment of postextraction areas with biomaterials associated with platelet-rich plasma (PRP) might make the repair process more efficient, resulting in desirable bone characteristics. The present study sought to evaluate the effectiveness of PRP in the process of new bone formation when associated with biomaterials.


METHODS
Four female dogs were used for this study. Mandibular postextraction sites received implants, along with bone substitutes (Bio-Oss [BO] or Biogran [BG]), on the right side of the mandible and these biomaterials plus PRP on the left side of the mandible. Thirty days later, the tissues were prepared and histologic analyses were carried out to compare the repair processes.


RESULTS
PRP accelerated the repair process for both BO and BG; however, the action of PRP associated with BO did not surpass that of BG alone.


CONCLUSIONS
The addition of PRP appears to accelerate the repair process.
Camarini
Edevaldo Tadeu
ET
Division of Oral and Maxillofacial Surgery, Academy of Dentistry, State University of Maringá, Paraná, Brazil. edevaldocamarini@wnet.com.br
Zanoni
Jacqueline Nelisis
JN
Leite
Pablo Cornelius Comelli
PC
Boos
Fernanda Brasil Daura Jorge
FB
D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D018786:Bone Substitutes; D004285:Dogs; D005260:Female; D005898:Glass; D008903:Minerals; D018919:Neovascularization, Physiologic; D053657:Platelet-Rich Plasma; D020390:Tooth Socket / Q000601:surgery*
C077540:Bio-Oss; D001672:Biocompatible Materials; C073544:Biogran; D018786:Bone Substitutes; D008903:Minerals