title: Biomarkers of exposure to metal contamination and lipid peroxidation in the benthic fish Cathorops spixii from two estuaries in South America, Brazil.
abstract: Biomarkers as lipid peroxidation, metallothionein and delta-aminolevulinic acid dehydratase were determined in Cathorops spixii to compare the biological responses of this fish from estuaries with distinct anthropogenic influence. Three areas were selected in two estuaries in accordance with the levels of contamination for the polluted (Santos/São Vicente) and with the hydrodynamic characteristics for the non-polluted (Cananéia) estuary. Water characteristics and mercury levels in C. spixii confirmed a high human influence in the polluted system. In general, the biomarkers showed differences between the estuaries, suggesting disturbances in the specific cell mechanisms due to the presence of multiple xenobiotics in the contaminated system. Therefore, these biomarkers are recommended to promote more accurate information about the exposure to pollutants. Additionally, the study of the effect of the multiple xenobiotics on resident species such as the benthic fish C. spixii can favor a better assessment of the environmental quality of these systems.
authors: Instituto Oceanográfico, Universidade de São Paulo, Praça do Oceanográfico, 191, Sao Paulo, Brazil. julianaazevedo_1978@yahoo.com.br
authors: J S
authors: JS
authors: Azevedo
authors: A
authors: A
authors: Serafim
authors: R
authors: R
authors: Company
authors: E S
authors: ES
authors: Braga
authors: D I
authors: DI
authors: Fávaro
authors: M J
authors: MJ
authors: Bebianno
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001938:Brazil; D002397:Catfishes / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008628:Mercury / Q000633:toxicity*; D008668:Metallothionein / Q000187:drug effects / Q000378:metabolism; D019216:Metals, Heavy / Q000633:toxicity; D000623:Porphobilinogen Synthase / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D008668:Metallothionein; D000623:Porphobilinogen Synthase; D008628:Mercury