Synthesis and characterization of bis[(2-ethyl-5-methyl-imidazo-4-yl)methyl]sulfide and its coordination behavior toward Cu(II) as a possible approach of a copper site type I.
The synthesis and characterization of a novel ligand, bis[(2-ethyl-5-methyl-imidazo-4-yl)methyl]sulfide (bemims), as well as a bemims-containing copper(II) coordination complex are described. In this complex, [Cu(bemims)X(2)] with X = NO(3) (-), bemims acts as a tridentate ligand and two monodentate nitrate ions complete the coordination sphere. Both imidazole N atoms and the thioether S atom of bemims participate in coordination. The Cu(II) ion is five-coordinated with a slightly distorted square-pyramidal geometry (tau = .09). Electrochemical studies and spectroscopic data for this complex are compared with some blue copper proteins in order to assess its ability to mimic the copper center of type I copper proteins.
Barrón-Garcés
Juan D
JD
Laboratorio de Química Bioinorgánica, Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, GTO, Mexico.
Mendoza-Díaz
Guillermo
G
Vilchez-Aguado
Florina
F
Bernès
Sylvain
S