Access to flavones via a microwave-assisted, one-pot Sonogashira-carbonylation-annulation reaction.
Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane are shown to be effective catalytic systems facilitating the sequential application of a microwave-assisted Sonogashira and carbonylative annulation reaction for the preparation of substituted flavones.
Awuah
Emelia
E
Department of Chemistry, McMaster University, Hamilton, Ontario, Canada L8S 4M1.
Capretta
Alfredo
A
D000218:Adamantane / Q000031:analogs & derivatives / Q000737:chemistry; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D047309:Flavones / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D010165:Palladium / Q000737:chemistry
C544841:1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane; D002867:Chromones; D047309:Flavones; D010165:Palladium; D000218:Adamantane