title: Risk of retinal neovascularization in the second eye in patients with proliferative diabetic retinopathy.
abstract: OBJECTIVE
  This study aimed to evaluate the risk of proliferative diabetic retinopathy (DR) in the fellow eye of an eye with existing proliferative DR.
  
  
  METHODS
  Our DR screening programme database listed 1513 diabetes patients alive at the time of the study. Seventy-six had proliferative DR in one or both eyes.
  
  
  RESULTS
  In 28 of the 76 (37%) diabetes patients, proliferative DR was diagnosed in both eyes at the same examination. Another 28 patients developed proliferative DR in the second eye within 5 years of its diagnosis in the first eye, bringing the total number of diabetes patients with proliferative DR in both eyes at 5 years to 56 (74%). Almost all the diabetes patients eventually developed proliferative DR in the second eye. The median duration of diabetes before the development of proliferative retinopathy was 19 years for type 1 and 14 years for type 2 diabetes.
  
  
  CONCLUSIONS
  Proliferative DR is a bilateral disease. Diabetes patients with proliferative DR in one eye are at high risk of developing neovascularization in the second eye and close follow-up is recommended.
authors: School of Medicine, University of Iceland, Reykjavik, Iceland.
authors: Edda
authors: E
authors: Vésteinsdóttir
authors: Sigrídur
authors: S
authors: Björnsdóttir
authors: Astrádur B
authors: AB
authors: Hreidarsson
authors: Einar
authors: E
authors: Stefánsson
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003930:Diabetic Retinopathy / Q000150:complications* / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015861:Retinal Neovascularization / Q000150:complications* / Q000175:diagnosis / Q000209:etiology*; D012307:Risk Factors; D013997:Time Factors; D014792:Visual Acuity; D055815:Young Adult