title: Cytotoxic triterpenoids from the rhizomes of Astilbe chinensis.
abstract: Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.
authors: Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea.
authors: Xing-Fu
authors: XF
authors: Cai
authors: Bo-Young
authors: BY
authors: Park
authors: Kyung-Seop
authors: KS
authors: Ahn
authors: Ok-Kyoung
authors: OK
authors: Kwon
authors: Hyeong-Kyu
authors: HK
authors: Lee
authors: Sei-Ryang
authors: SR
authors: Oh
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007723:Korea; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D031995:Saxifragaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes