title: A hyperelastic constitutive law for aortic valve tissue.
abstract: The objective of the present study was to perform biaxial testing and apply constitutive modeling to develop a strain energy function that accurately predicts the material behavior of the aortic valve leaflets. Ten leaflets from seven normal porcine aortic valves were biaxially stretched in a variety of protocols and the data combined to develop and fit a strain energy function to describe the material behavior. The results showed that the nonlinear anisotropic behavior of the aortic valve is well described by a strain energy function of two strain invariants, which uses only three coefficients to accurately predict the stress-strain behavior over a wide range of deformations. This structurally-motivated constitutive law has many applications, including computational modeling for clinical and engineering valve treatments.
authors: Department of Mechanical Engineering, San Diego State University, San Diego, CA 92182-1323, USA. kmn@kahuna.sdsu.edu
authors: Karen
authors: K
authors: May-Newman
authors: Charles
authors: C
authors: Lam
authors: Frank C P
authors: FC
authors: Yin
mesh_terms: D001021:Aortic Valve / Q000502:physiology*; D003198:Computer Simulation; D055119:Elastic Modulus / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D013314:Stress, Mechanical; D013718:Tensile Strength