title: Electrosurgical loop excision/conisation for cervical intraepithelial neoplasia in an algorithm that excludes punch biopsy--a study of 210 cases.
abstract: This study aims to evaluate the use of LLETZ/conisation in an algorithm that excludes the colposcopically guided biopsy.
  
  
  METHODS
  The study was carried out on 210 patients with LLETZ/conisation, performed in our service in 2 years. They were selected by pap smear, colposcopy, HPV genotyping, without punch biopsy.
  
  
  RESULTS
  The pathological results on the excision specimen showed: benign lesion 10%, CIN 1/condyloma 58%, CIN 2 18%, CIN 3/CIS 11%, microinvasion 2% and invasion 1%. The Pap test showed: HGSIL 27%, LGSIL 56%, ASCUS 13%, and normal/benign in 4%. The therapeutic efficiency of the excisional treatment showed that there was a 9.5% excessive treatment, 14.8 residual lesions, 3 cases of hemorrhage, 2 cervical stenosis, and 7 cases with specimen alteration that made the pathological diagnostic difficult or impossible. In conclusion, the LLETZ/conisation are ambulatory procedures with an acceptable rate of over-treatment and residual lesions, and reduced rate of complication.
authors: Department Obstetrics and Gynecology, University of Medicine and Pharmacy "Gr.T. Popa", Iasi, Romania. socolov@hotmail.com
authors: D
authors: D
authors: Socolov
authors: G
authors: G
authors: Anton
authors: A C
authors: AC
authors: Anton
authors: E
authors: E
authors: Anton
authors: R V
authors: RV
authors: Socolov
authors: S
authors: S
authors: Teleman
authors: A
authors: A
authors: Melinte
authors: L
authors: L
authors: Boiculese
authors: M
authors: M
authors: Stoian
mesh_terms: D000328:Adult; D000465:Algorithms; D001707:Biopsy, Needle; D003127:Colposcopy / Q000379:methods; D019092:Conization; D004598:Electrosurgery / Q000379:methods*; D005260:Female; D005838:Genotype; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008875:Middle Aged; D065006:Papanicolaou Test; D027383:Papillomaviridae / Q000235:genetics; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery*; D014626:Vaginal Smears / Q000379:methods; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000601:surgery*