[Vasectomy not associated with prostate cancer: a meta-analysis].
OBJECTIVE
To evaluate the association between vasectomy and prostate cancer.


METHODS
We searched comprehensively the databases, CBMDisc, CMCC, CMAC, CNKI (from 1978 to January 6, 2009), and PubMed (from 1965 to January 6, 2009) using the key words "vasectomy" and "prostate cancer", screened the retrieved literature according to the inclusion and exclusion criteria, performed a Meta-analysis with the software RevMan 4.2 after identification of the relevant data, and calculated the overall pooled OR (95% CI) as well as that of the association of prostate cancer with <20 and > or =20 yr vasectomy.


RESULTS
A total of 20 088 cases and 232 506 controls in 27 reports (7 cohort and 20 case-control studies) were included in this investigation. The overall pooled OR (95% CI) was 1.10 (0.97-1.24), and those of <20 and > or =20 yr vasectomy were 0.94 (0.83-1.06) and 1.05 (0.90-1.23), respectively.


CONCLUSIONS
No existing literature show any positive association between vasectomy and prostate cancer.
Tang
Ling-feng
LF
Department of Urology, The Third Hospital of Peking University, Beijing 100191, China. lingfengtang@bjmu.edu.cn
Jiang
Hui
H
Shang
Xue-jun
XJ
Zhao
Lian-ming
LM
Bai
Quan
Q
Hong
Kai
K
Liu
De-feng
DF
Liu
Jian-ming
JM
Yuan
Ren-pei
RP
Chen
Qian
Q
Ma
Lu-lin
LL
D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D012307:Risk Factors; D014659:Vasectomy / Q000009:adverse effects*