title: Risk factors for mortality in traumatic cervical spinal cord injury: Brazilian data.
abstract: BACKGROUND
  Predictive factors for mortality are different among countries; knowledge of risk factors is important for planning strategies to reduce mortality in trauma. The objective of this study was to identify predictors of death in traumatic cervical spinal cord injury (TSCI) in Brazil.
  
  
  METHODS
  From 2001 to 2005, 84 patients with clinically detectable TSCI were identified in this retrospective study. For each patient, neurologic and associated injuries, physiologic variables, complications, treatment, and hospital mortality were recorded. Bivariate and multivariate logistic regression analyses were done to identify predictors of mortality.
  
  
  RESULTS
  Twenty-two (26.2%) patients died in hospital. Car crash (39%) and falls (37.85) were the most frequent causes of trauma. The causes of death were as follows: neurologic, 8 (36.4%); respiratory, 4 (18.2%); septic complications, 2 (9.1%); venous thrombosis and embolism, 2 (9.1%); and undetermined, 4 (18.2%). Bivariate analysis identified absent neurologic function (risk ratios [RR] = 4.5; 95% confidence intervals [CI], 1.6-12.7), high injury severity score (p = 0.001) and low revised trauma score (p = 0.001); Glasgow Coma Scale (GCS) score <9 (RR = 47.4; 95% CI, 5.4-413.2); shock at admission (RR = 2.5; 95% CI, 0.8-7.9); vasopressor use (RR = 25.8; 95% CI, 6.1-109.6); mechanical ventilation (RR = 31.9; 95% CI, 6.6-154.0); acute renal insufficiency (RR = 10.0; 95% CI, 0.98-102.1) as associated with mortality. The mainly independents predictors for mortality were GCS score <9 and vasopressor use. Lowest mortality rate (5.2%) was observed for patients with TSCI alone.
  
  
  CONCLUSIONS
  GCS score <9, mechanical ventilation, and vasopressor use were predictors of mortality with TCSI, and if these risk factors were absent, we observed low mortality rate.
authors: Social Medicine Department, School of Medicine, Federal University of Rio Grande do Sul, Intensivist of Hospital de Pronto Socorro Municipal de Porto Alegre, Porto Alegre, Brazil. cristinaneumann@via-rs.net
authors: Cristina R
authors: CR
authors: Neumann
authors: Albert V
authors: AV
authors: Brasil
authors: Felix
authors: F
authors: Albers
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002423:Cause of Death / Q000639:trends; D002574:Cervical Vertebrae; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000379:methods; D011379:Prognosis; D012121:Respiration, Artificial / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D012772:Shock, Septic / Q000150:complications / Q000401:mortality*; D013119:Spinal Cord Injuries / Q000150:complications / Q000401:mortality* / Q000628:therapy; D015996:Survival Rate / Q000639:trends; D015599:Trauma Severity Indices; D014662:Vasoconstrictor Agents / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D014662:Vasoconstrictor Agents