Isolation of Streptomyces sp. strain capable of butyltin compounds degradation with high efficiency.
Dibutyltin (DBT), a widely used plastic stabilizer, has been detected in the environment as well as in human tissues. DBT is considered to be highly neurotoxic and immunotoxic. Hence, DBT needs to be considered as a potential toxic chemical. Degradation of butyltin compounds by Streptomyces sp. isolated from plant waste composting heaps was studied. Glucose grown cells degraded organotin from 10 to 40 mg l(-1). After 1 day of incubation 90% of DBT (added at 20 mg l(-1)) was converted to less toxic derivative--monobutyltin (MBT). DBT metabolism was inhibited by metyrapone addition, a known cytochrome P-450 inhibitor. It could provide evidence that cytochrome P-450 system is involved in DBT metabolism in Streptomyces sp. IM P102. Moreover, according to our knowledge, the degradation of DBT by actinobacterium has not been previously described.
Bernat
Przemysław
P
Department of Industrial Microbiology and Biotechnology, University of Lodz, Banacha 12/16, 90-237 Łódź, Poland.
Długoński
Jerzy
J
D001673:Biodegradation, Environmental; D018533:Biomass; D002849:Chromatography, Gas / Q000379:methods; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry; D017753:Ecosystem; D004784:Environmental Monitoring / Q000379:methods; D005227:Fatty Acids / Q000737:chemistry; D009947:Organotin Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D012623:Seawater; D013302:Streptomyces / Q000378:metabolism*; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000378:metabolism / Q000494:pharmacology; D018508:Water Purification / Q000379:methods
D005227:Fatty Acids; D009947:Organotin Compounds; D014874:Water Pollutants, Chemical; C516409:mono-n-butyltin; C056189:di-n-butyltin; D003577:Cytochrome P-450 Enzyme System