Epidemiology of methicillin-resistant Staphylococcus aureus bacteremia in Gaborone, Botswana.
This cross-sectional study at a tertiary-care hospital in Botswana from 2000 to 2007 was performed to determine the epidemiologic characteristics of Staphylococcus aureus bacteremia. We identified a high prevalence (11.2% of bacteremia cases) of methicillin-resistant S. aureus (MRSA) bacteremia. MRSA isolates had higher proportions of resistance to commonly used antimicrobials than did methicillin-susceptible isolates, emphasizing the need to revise empiric prescribing practices in Botswana.
Wood
Sarah M
SM
Children's Hospital of Philadelphia, PA 19104, USA. woodsa@email.chop.edu
Shah
Samir S
SS
Bafana
Margaret
M
Ratner
Adam J
AJ
Meaney
Peter A
PA
Malefho
Kolaatamo C S
KC
Steenhoff
Andrew P
AP
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000453:epidemiology* / Q000635:transmission; D001902:Botswana / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003428:Cross Infection / Q000453:epidemiology* / Q000635:transmission; D003430:Cross-Sectional Studies; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000635:transmission; D055815:Young Adult
D000900:Anti-Bacterial Agents