title: Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system.
abstract: A mesoporous silica nanoparticle-based intracellular cysteine delivery system that could be induced and regulated by cell-produced natural antioxidants was synthesized.
authors: Dipartimento di Scienza dei Materiali e Ingegneria Chimica Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 Torino, Italy.
authors: Renato
authors: R
authors: Mortera
authors: Juan
authors: J
authors: Vivero-Escoto
authors: Igor I
authors: II
authors: Slowing
authors: Edoardo
authors: E
authors: Garrone
authors: Barbara
authors: B
authors: Onida
authors: Victor S-Y
authors: VS
authors: Lin
mesh_terms: D000975:Antioxidants / Q000378:metabolism; D002463:Cell Membrane Permeability; D049109:Cell Proliferation / Q000187:drug effects; D003545:Cysteine / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D004337:Drug Carriers / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D042541:Intracellular Space / Q000378:metabolism*; D053768:Metal Nanoparticles / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D004337:Drug Carriers; D012822:Silicon Dioxide; D003545:Cysteine