Aromatase inhibitor for treatment of a recurrent abdominal wall endometrioma in a postmenopausal woman.
OBJECTIVE
Treat an abdominal wall endometrioma in a post-menopausal patient.


METHODS
Case report.


METHODS
Academic medical center.


METHODS
A post-menopausal women with a large recurrent abdominal wall endometrioma.


METHODS
The patient was managed with the combination of an aromatase inhibitor, a progestin, and serial cyst aspiration.


METHODS
Serum and cyst estradiol levels as well as sonographic demonstration of resolution.


RESULTS
Serum and cyst estradiol levels were significantly diminished and the cyst diminished in size.


CONCLUSIONS
Taken together, this case demonstrates a novel approach for managing and monitoring medical therapy for unusual clinical presentations of endometriosis. Furthermore, it illustrates that endometriotic implants can be a source of circulating estrogen in postmenopausal women, and that this source of estrogen is generated by increased aromatase activity.
Sasson
Isaac E
IE
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut.
Taylor
Hugh S
HS
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut; Division of Reproductive Endocrinology, Yale University School of Medicine, New Haven, Connecticut. Electronic address: hugh.taylor@yale.edu.
D034861:Abdominal Wall; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000077289:Letrozole; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use*; D017698:Postmenopause; D012008:Recurrence; D013896:Thoracic Diseases / Q000188:drug therapy*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use*
D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077289:Letrozole