title: A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure.
abstract: We aimed to examine the effect of different doses of lutein supplementation on visual function in subjects with long-term computer display light exposure. Thirty-seven healthy subjects with long-term computer display light exposure ranging in age from 22 to 30 years were randomly assigned to one of three groups: Group L6 (6 mg lutein/d, n 12); Group L12 (12 mg lutein/d, n 13); and Group Placebo (maltodextrin placebo, n 12). Levels of serum lutein and visual performance indices such as visual acuity, contrast sensitivity and glare sensitivity were measured at weeks 0 and 12. After 12-week lutein supplementation, serum lutein concentrations of Groups L6 and L12 increased from 0.356 (SD 0.117) to 0.607 (SD 0.176) micromol/l, and from 0.328 (SD 0.120) to 0.733 (SD 0.354) micromol/l, respectively. No statistical changes from baseline were observed in uncorrected visual acuity and best-spectacle corrected visual acuity, whereas there was a trend toward increase in visual acuity in Group L12. Contrast sensitivity in Groups L6 and L12 increased with supplementation, and statistical significance was reached at most visual angles of Group L12. No significant change was observed in glare sensitivity over time. Visual function in healthy subjects who received the lutein supplement improved, especially in contrast sensitivity, suggesting that a higher intake of lutein may have beneficial effects on the visual performance.
authors: Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xueyuan Road, Beijing 100191, P. R. China.
authors: Le
authors: L
authors: Ma
authors: Xiao-Ming
authors: XM
authors: Lin
authors: Zhi-Yong
authors: ZY
authors: Zou
authors: Xian-Rong
authors: XR
authors: Xu
authors: Ying
authors: Y
authors: Li
authors: Rui
authors: R
authors: Xu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D044466:Asian People; D016009:Chi-Square Distribution; D016288:Computer Terminals; D015350:Contrast Sensitivity / Q000187:drug effects; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D019466:Glare / Q000009:adverse effects; D006801:Humans; D014975:Lutein / Q000008:administration & dosage* / Q000097:blood; D008297:Male; D011446:Prospective Studies; D016896:Treatment Outcome; D014785:Vision, Ocular / Q000187:drug effects*; D014792:Visual Acuity / Q000187:drug effects; D055815:Young Adult
chemical_list: D014975:Lutein