[Starch and its derivatives as excipients in oral and parenteral drug form technology].
The morphological and structural properties of basic types of starch used as excipients in solid drug form technology with reference to its bioadhesive properties with fully polymer biodegradation. The production technology and application of: carboxymethyl starch (CMS), pregelled starch, hydroxyethyl starch (HES), hydroxypropyl starch (HPS) and the share of modified starch in technology of selected food products is provided. The authors focus on hydroxyethyl starch, which is used not only as blood and plasma substitution but also as drug camouflage agent in sports competition. In papers were presented based on literature data actually used types of starch and their chemical modifications products in drug forms and food technology.
Zgoda
Marian Mikołaj
MM
Zakład Technologii Postaci Leku, Katedra Farmacji Stosowanej, Uniwersytetu Medycznego w Lodzi. mmzgoda@pharm.am.lodz.pl
Kolodziejczyk
Michał Krzysztof
MK
Nachajski
Michał Jakub
MJ
D020341:Absorbable Implants; D000269:Adhesives / Q000737:chemistry; D000284:Administration, Oral; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D003358:Cosmetics / Q000737:chemistry; D005079:Excipients / Q000737:chemistry*; D005524:Food Technology / Q000379:methods; D007263:Infusions, Parenteral; D008961:Models, Structural; D013213:Starch / Q000031:analogs & derivatives* / Q000737:chemistry*
D000269:Adhesives; D003358:Cosmetics; D005079:Excipients; D013213:Starch