Kaposi-like vascular tumor of the urinary bladder in a cow.
Kaposiform hemangioendothelioma is a rare human vascular neoplasm. In veterinary medicine this tumor type was only recognized in the dog. Here we describe an unusual case arising in the urinary bladder of a Holstein-Friesian adult cow. Histologically the tumor presented a nodular proliferation of spindle cells, forming angular slits, often containing extravasated erythrocytes. Peripherically, well-formed vascular channels were seen. These cells were positive to vimentin and to factor VIII-related antigen by immunohistochemical stain. Based on its characteristics, it was classified as kaposiform hemangioendothelioma and as far as we know, it is the first case described in cattle.
Pires
Isabel
I
CECAV, Department of Veterinary Sciences, Universidade de Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal. ipires@utad.pt
Queiroga
Felisbina Luisa
FL
Silva
Filipe
F
Pinto
Carlos
C
Lopes
Carlos
C
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000662:veterinary*; D019043:Vascular Neoplasms / Q000473:pathology / Q000662:veterinary*