Cytotoxic guaianolide from Anthemis segetalis (Asteraceae).
Two epimeric guaianolides were isolated from the aerial parts of Anthemis segetalis. These compounds have not been detected in any Anthemis species so far. One of them was tested for cytotoxicity against human cervical cancer (HeLa) and murine melanoma (B16) cell lines showing appreciable activity.
Vucković
Ivan
I
Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia.
Vujisić
Ljubodrag
L
Stesević
Danijela
D
Radulović
Sinisa
S
Lazić
Milan
M
Milosavljević
Slobodan
S
D000818:Animals; D031166:Anthemis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008958:Models, Molecular; D015394:Molecular Structure; D010936:Plant Extracts / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane / Q000302:isolation & purification / Q000494:pharmacology*
D010936:Plant Extracts; D045789:Sesquiterpenes, Guaiane