Recent highlights in the synthesis of highly functionalized pyrimidines.
The pyrimidine scaffold represents an important pharmacophore endowed with a wide range of pharmacological activities according to the specific decoration of the heterocycle. This perspective article will briefly outline the most interesting approaches recently reported for the synthesis of highly functionalized pyrimidine derivatives.
Radi
Marco
M
Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Alcide de Gasperi 2, I-53100, Siena, Italy.
Schenone
Silvia
S
Botta
Maurizio
M
D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry
D000998:Antiviral Agents; D011743:Pyrimidines