[Two cases of probable immune restoration syndrome under antiretroviral treatment in patients treated for tuberculosis in Gabon].
Tuberculosis can be reactivated under specific treatment, as immune reconstitution inflammatory syndrome (IRIS), in HIV patients under antiretroviral treatment. We report two observations of tuberculosis exacerbation with extension to other territories (lymph node and pericarditis) occurring 3 weeks and 4 months after administration of tuberculosis treatment, with a favourable development, in absence of rehabilitation or addition of complementary therapy These observations show the necessity of increased surveillance on the short, medium and long term in patients with both treatment for tuberculosis and antiretroviral treatment.
Iba-Ba
J
J
Service de médecine A, Centre hospitalier de Libreville, BP 2228, Libreville, Gabon. ibabajose@yahoo.fr
Igala
M
M
Mipinda
J B
JB
Bignoumba Ibouili
R
R
Eke
E
E
Makandja
R
R
Moubamba
F
F
Nzamba
C
C
Coniquet
S
S
Moussavou Kombila
J B
JB
Boguikouma
J B
JB
D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000139:chemically induced / Q000150:complications*; D012367:RNA, Viral / Q000097:blood; D012008:Recurrence; D019562:Viral Load
D019380:Anti-HIV Agents; D012367:RNA, Viral