[Augmentation of quality of wound healing of deep burn].
This article summarizes methods of repair of massive and deep wounds, elucidates how to improve wound healing quality and avoid scar deformity after deep burn. A part of denatured dermis (non-necrotic) in deep partial-thickness burn, "mixed degree" burn, even in full-thickness burn wounds before forming eschar can be preserved and covered with autologous skin, thereby to avoid secondary damage to the structure of subcutaneous tissue and the junction of dermis-adipose, thus to result in good functions, appearance, and survival rate. After skin grafting, wound healing quality and appearance are improved, joint function and elasticity of skin are enhanced, the degree of scar contracture is relieved due to preservation of normal adipose tissue after escharectomy. The study of composite artificial skin will be actively developed in the future. Tissue-engineering skin and stem cells can be successfully used in patients with deep burns for scarless healing with restoration of physiological functions in a short period.
Huang
Xiao-yuan
XY
Department of Burns and Plastic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
D000273:Adipose Tissue / Q000637:transplantation; D002056:Burns / Q000601:surgery* / Q000628:therapy; D006801:Humans; D019651:Plastic Surgery Procedures; D016038:Skin Transplantation; D023822:Tissue Engineering; D014945:Wound Healing