[Anti-aging medicine: the evidence to the value of the antihypertensive drugs, hypoglycemic drugs and statins].
Aging is associated with a large increase in the prevalence and incidence of arteriosclerotic diseases including cerebrovascular disease and coronary artery disease. Prevention of arteriosclerosis is a major challenge in order to increase longevity of populations. Hypertension, diabetes and dyslipidemia are known as lifestyle-related diseases and risk factors for arteriosclerosis. The tight control of blood pressure, glucose and LDL cholesterol is important in preventing arteriosclerosis. Many clinical trials have been revealed pleiotropic effects among antihypertensive drugs, hypoglycemic drugs and statins, and these effects are useful for anti-aging. Selection of appropriate medicines to manage the risk factors would be a way to prevent senescence.
Okumachi
Yasuyo
Y
Department of Internal and Geriatric Medicine, Kobe University Graduate School of Medicine.
Yokono
Koichi
K
D000368:Aged; D000375:Aging / Q000187:drug effects*; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D007004:Hypoglycemic Agents / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007004:Hypoglycemic Agents