title: Kaposi-like vascular tumor of the urinary bladder in a cow.
abstract: Kaposiform hemangioendothelioma is a rare human vascular neoplasm. In veterinary medicine this tumor type was only recognized in the dog. Here we describe an unusual case arising in the urinary bladder of a Holstein-Friesian adult cow. Histologically the tumor presented a nodular proliferation of spindle cells, forming angular slits, often containing extravasated erythrocytes. Peripherically, well-formed vascular channels were seen. These cells were positive to vimentin and to factor VIII-related antigen by immunohistochemical stain. Based on its characteristics, it was classified as kaposiform hemangioendothelioma and as far as we know, it is the first case described in cattle.
authors: CECAV, Department of Veterinary Sciences, Universidade de Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal. ipires@utad.pt
authors: Isabel
authors: I
authors: Pires
authors: Felisbina Luisa
authors: FL
authors: Queiroga
authors: Filipe
authors: F
authors: Silva
authors: Carlos
authors: C
authors: Pinto
authors: Carlos
authors: C
authors: Lopes
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000662:veterinary*; D019043:Vascular Neoplasms / Q000473:pathology / Q000662:veterinary*