title: Mismatch DNA-specific enzymatic cleavage employed in a new method for the electrochemical detection of genetic mutations.
abstract: Utilizing enzymatic mismatched DNA-specific cleavage and electrocatalytic signaling, a new electrochemical method for the detection of DNA mutations was developed and successfully applied to detect various mutations in the BRCA1 gene.
authors: Department of Chemical and Biomolecular Engineering, KAIST, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea.
authors: Byoung Yeon
authors: BY
authors: Won
authors: Sung Chul
authors: SC
authors: Shin
authors: Won-young
authors: WY
authors: Chung
authors: Sujeong
authors: S
authors: Shin
authors: Dae-Yeon
authors: DY
authors: Cho
authors: Hyun Gyu
authors: HG
authors: Park
mesh_terms: D020137:Base Pair Mismatch; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004563:Electrochemistry / Q000379:methods*; D019398:Genes, BRCA1; D006801:Humans; D009154:Mutation
chemical_list: D004247:DNA