[Controversy: botulinum toxin, does it prevent cutaneous aging?].
By blocking muscular contraction, even if this effect is reversible, botulinum toxin injected early and regularly to prevent aging modifies the facial traits and can result in muscular and cutaneous atrophy. Mechanical information is indispensable to cell survival and conditions the function of fibroblastic synthesis. Aging cannot be reduced to the facial lines; botulinum toxin cannot prevent the other parameters of age such as drying, pigmentation problems, vascular problems, and loss of volume.
Cohen-Letessier
A
A
anny.cohen-letessier@wanadoo.fr
D001905:Botulinum Toxins / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D005145:Face; D005347:Fibroblasts / Q000187:drug effects*; D006801:Humans; D007267:Injections / Q000379:methods; D009119:Muscle Contraction / Q000187:drug effects*; D009133:Muscular Atrophy / Q000139:chemically induced*; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D012060:Rejuvenation; D015595:Skin Aging / Q000187:drug effects*; D017211:Treatment Failure
D003879:Dermatologic Agents; D009465:Neuromuscular Agents; D001905:Botulinum Toxins