title: In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates.
abstract: The antimicrobial activities of telavancin and six comparators were evaluated against 460 isolates of anaerobic bacteria. Telavancin demonstrated excellent activity against gram-positive anaerobes (MIC90, 2 microg/ml) and was the most potent agent tested against Clostridium difficile (MIC90, 0.25 microg/ml). As expected, gram-negative isolates were not inhibited by telavancin.
authors: Medical Service, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California, USA. sidfinegol@aol.com
authors: Sydney M
authors: SM
authors: Finegold
authors: Mauricio
authors: M
authors: Bolanos
authors: Paula H
authors: PH
authors: Sumannen
authors: Denise R
authors: DR
authors: Molitoris
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D016360:Clostridioides difficile / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D000077427:Lipoglycopeptides; D008826:Microbial Sensitivity Tests
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000077427:Lipoglycopeptides; C487637:telavancin