In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates.
The antimicrobial activities of telavancin and six comparators were evaluated against 460 isolates of anaerobic bacteria. Telavancin demonstrated excellent activity against gram-positive anaerobes (MIC90, 2 microg/ml) and was the most potent agent tested against Clostridium difficile (MIC90, 0.25 microg/ml). As expected, gram-negative isolates were not inhibited by telavancin.
Finegold
Sydney M
SM
Medical Service, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California, USA. sidfinegol@aol.com
Bolanos
Mauricio
M
Sumannen
Paula H
PH
Molitoris
Denise R
DR
D000617:Aminoglycosides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D016360:Clostridioides difficile / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D000077427:Lipoglycopeptides; D008826:Microbial Sensitivity Tests
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000077427:Lipoglycopeptides; C487637:telavancin