title: Clinical outcomes and advantages of laparoscopic surgery for primary Crohn's disease: are they significant?
abstract: OBJECTIVE
  The clinical outcomes and advantages of laparoscopic surgery for Crohn's disease have not yet been recognized in general. The aim of this study was to critically assess the clinical outcomes, safety, cosmesis, quality of life (QOL) and feasibility of laparoscopic surgery for primary Crohn's disease.
  
  
  METHODS
  The study subjects consisted of 48 patients who had primary surgical treatment for Crohn's disease, 28 through conventional laparotomy and 20 in whom surgery was laparoscopically assisted. The short-term and long-term outcomes, cosmesis, and postoperative QOL were evaluated in both groups.
  
  
  RESULTS
  There were no statistically significant differences in the patient characteristics between the two groups. In the laparoscopic group, non-resected procedures were significantly more frequent (p < 0.05), blood loss was less (p < 0.05), oral intake was started earlier (p < 0.05) and the length of the skin incision was shorter (P < 0.01). The C-reactive protein values and leukocyte counts were not significantly different in the two groups. The cosmetic results were very satisfactory in 11 patients (64.7%). There were no severe complications and no increase of the recurrence rate for laparoscopic surgery. Moreover, there was no definite clinical disadvantage and no prolonged operating time in the laparoscopic procedures.
  
  
  CONCLUSIONS
  Laparoscopic surgery for primary Crohn's disease is safe and feasible in selected patients without severe adhesion, fistula or abscess, and was associated with better cosmesis than conventional open surgery. Therefore, laparoscopic procedures should be considered as the preferred operative approach for a primary bowel resection.
authors: Department of Gastroenterological Surgery, Fukuoka University School of Medicine Nanakuma 7-45-1, Jonan-ku, Fukuoka, 814-0180, Japan. t-shin@fukuoka-u.ac.jp
authors: Shinnosuke
authors: S
authors: Tanaka
authors: Katsuichi
authors: K
authors: Matsuo
authors: Takamitsu
authors: T
authors: Sasaki
authors: Masahiho
authors: M
authors: Nakano
authors: Hideo
authors: H
authors: Shimura
authors: Yuichi
authors: Y
authors: Yamashita
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D003424:Crohn Disease / Q000601:surgery*; D004954:Esthetics; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011788:Quality of Life; D012086:Reoperation; D012449:Safety; D018709:Statistics, Nonparametric; D016896:Treatment Outcome