title: Amino acid synthesis in a supercritical carbon dioxide - water system.
abstract: Mars is a CO(2)-abundant planet, whereas early Earth is thought to be also CO(2)-abundant. In addition, water was also discovered on Mars in 2008. From the facts and theory, we assumed that soda fountains were present on both planets, and this affected amino acid synthesis. Here, using a supercritical CO(2)/liquid H(2)O (10:1) system which mimicked crust soda fountains, we demonstrate production of amino acids from hydroxylamine (nitrogen source) and keto acids (oxylic acid sources). In this research, several amino acids were detected with an amino acid analyzer. Moreover, alanine polymers were detected with LC-MS. Our research lights up a new pathway in the study of life's origin.
authors: International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.|Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan.
authors: Kouki
authors: K
authors: Fujioka
authors: International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
authors: Yasuhiro
authors: Y
authors: Futamura
authors: Sekisui Chemical Co., Ltd., 2-1 Hyakuyama, Shimamoto-cho, Mishima-gun, Osaka, Japan.
authors: Tomoo
authors: T
authors: Shiohara
authors: International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
authors: Akiyoshi
authors: A
authors: Hoshino
authors: International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
authors: Fumihide
authors: F
authors: Kanaya
authors: Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan.
authors: Yoshinobu
authors: Y
authors: Manome
authors: International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
authors: Kenji
authors: K
authors: Yamamoto
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D019811:Hydroxylamine / Q000737:chemistry; D007651:Keto Acids / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D013696:Temperature; D014867:Water / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D007651:Keto Acids; D010455:Peptides; D014867:Water; D002245:Carbon Dioxide; C019529:polyalanine; D019811:Hydroxylamine