title: [Sexual exposure to HIV, sexual behaviour and use of pharmacological post-exposure prophylaxis (PEP)].
abstract: In this study we examined the characteristics of 60 subjects (49 M and 11 F, average age 32.3) out of 195 post-exposure pharmacological prophylaxis (PEP) to HIV, taken in our hospital from 2001 to 2008. The above-mentioned subjects are sexually exposed (or presumably exposed) to HIV. We considered both their sexual intercourse behaviour and protective measures, and sought to infer some trends in sexual behaviour in Italy. All the subjects were monitored until 180 days after exposure, as established by the national guidelines. Only one of the 60 people presented a seroconversion (he dropped out after a 15-day follow-up and after an inadequate 19-day prophylaxis). Another subject, a homosexual male, never previously tested, resulted positive at time 0 both for HIV-Ab and syphilis tests (due to previous risk-sexual exposure), which caused the suspension of the prophylaxis. No HBV, HCV or syphilis seroconversion occurred. Two other homosexual males showed a previously latent positivity to syphilis tests at time 0.
authors: Azienda Ospedaliera di Rilievo Nazionale D Cotugno, Napoli, Italy.
authors: Alfredo
authors: A
authors: Franco
authors: Fabrizio
authors: F
authors: Starace
authors: Lucia
authors: L
authors: Aprea
authors: Francesco Saverio
authors: FS
authors: Faella
authors: Antonio
authors: A
authors: Giordano
authors: Cosimo
authors: C
authors: Maiorino
authors: Elio
authors: E
authors: Manzillo
authors: Alessandro
authors: A
authors: Marocco
authors: Fiorella
authors: F
authors: Martucci
authors: Teresa
authors: T
authors: Pizzella
authors: Francesco
authors: F
authors: Simioli
authors: Crescenzo Maria
authors: CM
authors: Izzo
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017280:Condoms / Q000706:statistics & numerical data; D003376:Counseling; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D015397:Program Evaluation; D011902:Rape; D012042:Registries; D012189:Retrospective Studies; D012309:Risk-Taking; D012725:Sexual Behavior; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D019380:Anti-HIV Agents