title: Cutaneous mast cell tumour within a lipoma in a boxer.
abstract: This report describes a case of a canine cutaneous grade I mast cell tumour which developed within a lipoma in the right axillar region of an 8-year-old male Boxer. Immunohistologically, the neoplastic mast cells were positive for serotonin, CD45 vimentin and p53, and negative for lysozyme, CD3 and CD79a expression. The proliferation index of the mast cell tumour based on the Ki-67 antigen was 6.1%. Between the benign neoplastic lipocytes and mastocytoma tumour cells intratumoural microvessels were detected by immunohistochemical staining using CD31 and claudin-5 as markers for vascular endothelium.
authors: Szent István University, Department of Pathology and Forensic Veterinary Medicine, Faculty of Veterinary Medicine, István utca 2 H-1078 Budapest, Hungary. Jakab.Csaba@aotk.szie.hu
authors: Csaba
authors: C
authors: Jakab
authors: Attila Marcell
authors: AM
authors: Szász
authors: Janina
authors: J
authors: Kulka
authors: Zsuzsa
authors: Z
authors: Schaff
authors: Miklós
authors: M
authors: Rusvai
authors: Tibor
authors: T
authors: Németh
authors: Péter
authors: P
authors: Gálfi
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D007150:Immunohistochemistry; D008067:Lipoma / Q000473:pathology / Q000662:veterinary*; D008297:Male; D034801:Mastocytoma / Q000473:pathology / Q000662:veterinary*; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*