title: [Pathologic characteristics of residual carcinoma at incisal edge after gastrectomy for gastric cancer].
abstract: OBJECTIVE
  To explore the reason, features and preventive measures of residual carcinoma at incisal edge after gastric cancer operation.
  
  
  METHODS
  Clinical data of 108 cases with positive incisal margin(6.47%) from December 1964 to December 2004 in Cancer Center of Sun Yat-sen were summarized and analyzed retrospectively.
  
  
  RESULTS
  Positive incisal margin patients accounted for 6.5%(108/1670) of total gastric carcinoma cases during above period. There were 62 men and 46 women with median age of 54 years(ranged from 23 to 82). The residual carcinoma rates of incisal edge were 3.6%(48/1333) in radical resection group and 17.8%(60/337) in palliative resection group respectively(P=0.000). Also, the residual carcinoma rates were 2.3%(3/129) in early group, 6.8(105/1541) in advanced group(P=0.046), 4.5%(37/815) in distal gastrectomy group and 8.0%(55/689) in proximal group respectively(P=0.000). Residual carcinomas were related with pTNM stage, Borrmann type, tumor size, differentiation and invasion depth(P<0.05).
  
  
  CONCLUSIONS
  Superior gastric carcinoma, Borrmann III(, IIII( type advanced cancer, tumor diameter > or =5 cm, poor differentiation or undifferentiated type and serosa invaded easily result in residual carcinoma at incisal edge. The radical preventive measure is to ensure that incisal edge ought to exceed 5 cm apart from the tumor.
authors: Department of Abdominal Surgery, Cancer Center, Sun Yat-sen University,Guangzhou 510060, China. lwxsbs@medmail.com.cn
authors: Wei
authors: W
authors: Li
authors: Xiao-wei
authors: XW
authors: Sun
authors: You-qing
authors: YQ
authors: Zhan
authors: Yuan-xiang
authors: YX
authors: Guan
authors: Ying-bo
authors: YB
authors: Chen
authors: Da-zhi
authors: DZ
authors: Xu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D018365:Neoplasm, Residual / Q000473:pathology; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D055815:Young Adult