title: Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases.
abstract: Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy.
authors: MD, specialization student on Otorhinolaryngology at Núcleo de Otorrino BH.
authors: Vinicius Antunes
authors: VA
authors: Freitas
authors: PhD, Adjunct Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School.
authors: Helena Maria Gonçalves
authors: HMG
authors: Becker
authors: PhD, Adjunct Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School.
authors: Roberto Eustáquio Santos
authors: RES
authors: Guimarães
authors: Specialist on Otorhinolaryngology, ENT at Hospital das Clínicas da UFMG.
authors: Letícia Paiva
authors: LP
authors: Franco
authors: Specialist on Otorhinolaryngology, Otorhinolaryngologist.
authors: Fernando Fernandes
authors: FF
authors: Guimarães
authors: MD, Resident on General Practice.
authors: Marcelo Figueredo
authors: MF
authors: Martins
authors: PhD, Substitute Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School. ENT Service of the Hospital das Clínicas da Universidade Federal de Minas Gerais.
authors: Paulo Fernando Tormin
authors: PFT
authors: Crosara
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy