Aspergillus endophthalmitis in orthotopic liver transplantation.
In this report, we describe a patient with drug-induced liver failure who developed endogenous endophthalmitis after liver transplantation. Our patient's clinical course was so fulminant that the eye was lost in less than 1 month, without any response to therapy. Recognition of this infection is important because many patients die of disseminated Aspergillus infection, which may be detected early with bedside funduscopic examination by an ophthalmologist. Probably if the patient had referred to us earlier, it may have been possible to save the eye.
Hosseini
Hamid
H
Research Center of Shiraz University of Medical Sciences, Ophthalmology Department, Khalili Hospital, Shiraz, Iran.
Saki
Soraya
S
Saki
Nasrin
N
Eghtedari
Masoomeh
M
D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D001230:Aspergillus / Q000302:isolation & purification*; D002442:Ceftazidime / Q000627:therapeutic use; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D005123:Eye / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D009887:Ophthalmoscopy; D014184:Transplantation, Homologous / Q000009:adverse effects* / Q000379:methods; D014463:Ultrasonography; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D014640:Vancomycin; D000666:Amphotericin B; D002442:Ceftazidime