Visceral leishmaniasis in a patient with common variable immunodeficiency and evans syndrome: clinical remarks.
Visceral Leishmaniasis (VL) is a vector-borne zoonosis endemic in Southern Italy whose usual clinical features include fever, splenomegaly, pancytopenia and hypergammaglobulinemia. The clinical and biochemical picture may be misleading in patients with immunodeficiency diseases hampering the diagnosis. We describe a VL case in a patient whose spleen had been removed and who had Common Variable Immunodeficiency and Evans syndrome.
Maio
Patrizia
P
Infectious Diseases Department, A.O.R.N. S.G. Moscati, Avellino, Italy. patriziamaio@yahoo.it
Leone
Sebastiano
S
Volpe
Silvestro
S
dell'Aquila
Giuseppina
G
Giglio
Sergio
S
Magliocca
Mario
M
Nigro
Francesco Saverio
FS
Pacifico
Piera
P
Acone
Nicola
N
D000666:Amphotericin B / Q000008:administration & dosage; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000188:drug therapy; D000981:Antiprotozoal Agents / Q000008:administration & dosage; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000628:therapy; D005334:Fever; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007116:Immunization, Passive; D016867:Immunocompromised Host; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D013156:Splenectomy; D013921:Thrombocytopenia / Q000150:complications* / Q000601:surgery
D000981:Antiprotozoal Agents; D005938:Glucocorticoids; C068538:liposomal amphotericin B; D000666:Amphotericin B; D011241:Prednisone