Fluorodeoxyglucose positron emission tomography for the diagnosis of sarcoidosis in patients with unexplained chronic uveitis.
OBJECTIVE
To assess the value of fluorine-18 fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in patients with unexplained chronic uveitis.


METHODS
Retrospective review of 19 (18)F-FDG PET scans. All patients had normal chest CT. In the final analysis, the authors used criteria similar to the criteria of Abad et al. (Abad S, Meyssonier V, Allali J, et al. Association of peripheral multifocal choroiditis with sarcoidosis: a study of thirty-seven patients. Arthritis Rheum. 2004;51:974-982) for the diagnosis of sarcoidosis-associated uveitis.


RESULTS
Ten (53%) whole-body scans were consistent with sarcoidosis. At the end, subsequent mediastinal biopsies proved sarcoidosis in 3 patients; 2 patients were considered as presumed sarcoidosis, and 6 indeterminate sarcoidosis.


CONCLUSIONS
(18)F-FDG PET may show focal uptake suggestive of sarcoidosis in patients with unexplained uveitis.
Seve
Pascal
P
Department of Internal Medicine, Hotel Dieu, Hospices Civils de Lyon, Lyon, France. pascal.seve@chu-lyon.fr
Billotey
Claire
C
Janier
Marc
M
Grange
Jean-Daniel
JD
Broussolle
Christiane
C
Kodjikian
Laurent
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000000981:diagnostic imaging*; D014605:Uveitis / Q000000981:diagnostic imaging*
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18