Differential involvement of cholinergic mechanisms in activity and sociability in rats.
Four groups of six rats, injected with saline, 0.1, 0.25 or 1.0 mg/kg scopolamine, were tested in a 36 x 36 in. open field for 10 min. Scopolamine differentially affected ambulation, rearing, social contacts and the social and perimeter distances between rats; and increased corner preference. This experiment shows that several component responses of activity and sociability need to be recorded if a better understanding of the involvement of cholinergic mechanisms in behaviour is to be obtained.
Stewart
W
W
Department of Psychology, University of Tasmania, Hobart, Tasmania 7001, Australia.
Evans
D
D
Maynard
D
D