Evaluation of the Cavidi ExaVir Load assay (version 3) for plasma human immunodeficiency virus type 1 load monitoring.
We evaluated the new low-cost ExaVir Load (version 3) reverse transcriptase viral load assay against the Roche Cobas Amplicor assay. Results for samples tested using the reverse transcriptase assay correlated well with those obtained with the Roche assay (r = 0.85; n = 202). The version 3 reverse transcriptase assay shows improved sensitivity compared to the previous version.
Greengrass
Vicki L
VL
Clinical Research Laboratory, Centre for Virology, Macfarlane Burnet Institute for Medical Research and Public Health, 85 Commercial Road, Melbourne, Australia.
Plate
Megan M
MM
Steele
Pauline M
PM
Denholm
Justin T
JT
Cherry
Catherine L
CL
Morris
Lisa M
LM
Hearps
Anna
A
Crowe
Suzanne M
SM
D000328:Adult; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D010949:Plasma / Q000821:virology*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D019562:Viral Load / Q000379:methods*; D055815:Young Adult