The structure of the O-specific polysaccharide from the lipopolysaccharide of Burkholderia anthina.
The pathogenic mechanisms of Gram-negative infection in cystic fibrosis are only just beginning to be explored at molecular level. Several virulence factors have been defined, one of the most important is the lipopolysaccharide molecule. In order to fully understand the mechanisms of bacterial infection and host recognition a full structure/activity study of lipopolysaccharide is needed. In the present paper, we define the complete structure of the O-specific polysaccharide from the lipopolysaccharide from Burkholderia anthina, an uncommon pathogen of cystic fibrosis patients.
Carillo
Sara
S
Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli Federico II, Via Cintia, 4 I-80126 Napoli, Italy.
Silipo
Alba
A
Perino
Vincenzo
V
Lanzetta
Rosa
R
Parrilli
Michelangelo
M
Molinaro
Antonio
A
D019117:Burkholderia / Q000737:chemistry*; D002240:Carbohydrate Sequence; D003550:Cystic Fibrosis / Q000382:microbiology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D019081:O Antigens / Q000737:chemistry* / Q000302:isolation & purification
D019081:O Antigens