Three new vanilloid derivatives from the stems of Baccaurea ramiflora.
Three new (1-3) and four known (4-7) compounds were isolated from the stems of Baccaurea ramiflora. By analysis of 1D, 2D NMR, and MS data, the new compounds were identified as 4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D (1), 6'-O-vanilloylpicraquassioside D (2), and 6'-O-vanilloylicariside B(5) (3). Compound 1 exhibited significant DPPH radical-scavenging activity, with an IC(50) value of 36.9 microM, while compound 4 revealed weak antioxidant activity against H (2)O(2)-induced impairment in PC12 cells.
Yang
Xian-Wen
XW
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P R China.
He
Hong-Ping
HP
Ma
Yan-Lin
YL
Wang
Fang
F
Zuo
Yi-Qing
YQ
Lin
Hua
H
Li
Shun-Lin
SL
Li
Ling
L
Hao
Xiao-Jiang
XJ
D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds; D004187:Disaccharides / Q000302:isolation & purification* / Q000494:pharmacology; D006861:Hydrogen Peroxide; D020128:Inhibitory Concentration 50; D019684:Magnoliopsida / Q000737:chemistry*; D009005:Monosaccharides / Q000302:isolation & purification* / Q000494:pharmacology; D016716:PC12 Cells; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018547:Plant Stems; D051381:Rats
C549435:4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D; C549433:6'-O-vanilloylicariside B5; C549434:6'-O-vanilloylpicraquassioside D; D000975:Antioxidants; D001713:Biphenyl Compounds; D004187:Disaccharides; D009005:Monosaccharides; D010851:Picrates; D010936:Plant Extracts; D006861:Hydrogen Peroxide; C004931:1,1-diphenyl-2-picrylhydrazyl