The time of origin of Cajal-Retzius cells in the rat temporal cortex. An autoradiographic study.
Rat fetuses received tritiated thymidine on one of each of the following days of gestation: 9, 10, 11, 12, 13, 14 and 16. Animals were sacrificed on day 1 post partum. Perpendicular and tangential sections including temporal cortex were studied by electron microscopy and light microscopic autoradiography. Our results suggest that the formation of Cajal-Retzius cells (CRs) begins on day 12, reaches a peak on day 13, and continues on day 14. Earliest non-CR neurons of the temporal cortex (cells of the deepest stratum of layer VI) appear to be generated on day 13.
König
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N
Laboratoire de Neuromorphologie Fonctionnelle et Neuropathologie Expérimentale, Université de Montpellier II, Place E. Bataillon, 34060 Montpellier Cedex France.
Valat
J
J
Fulcrand
J
J
Marty
R
R