Picosecond polarized supercontinuum generation controlled by intermodal four-wave mixing for fluorescence lifetime imaging microscopy.
We present the generation of a picosecond polarized supercontinuum in highly birefringent multimodal microstructured fiber. The initial steps of the spectral broadening are dominated by intermodal four-wave mixing controlled by the specific fiber design. Using a low repetition rate ultra-stable solid state laser, a pulse train well-suited for versatile time-domain fluorescence lifetime imaging applications is obtained.
Blandin
Pierre
P
Laboratoire Charles Fabry de l'Institut d'Optique, CNRS, University Paris-Sud, Palaiseau, France.
Druon
Frederic
F
Hanna
Marc
M
Lévêque-Fort
Sandrine
S
Lesvigne
Christelle
C
Couderc
Vincent
V
Leproux
Philippe
P
Tonello
Alessandro
A
Georges
Patrick
P
D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D007089:Image Enhancement / Q000295:instrumentation*; D008856:Microscopy, Fluorescence / Q000295:instrumentation*; D008859:Microscopy, Polarization / Q000295:instrumentation*; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity