High-resolution cross-reactive array for alkaloids.
A high-resolution cross-reactive array capable of classifying alkaloids over a range of concentrations was generated by systematic introduction of a nitroindole analog into a hydrophobic pocket within a DNA three-way junction to match structural motifs presented by the analytes.
Pei
Renjun
R
Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, NY 10032, USA.
Shen
Aihua
A
Olah
Mark J
MJ
Stefanovic
Darko
D
Worgall
Tilla
T
Stojanovic
Milan N
MN
D000470:Alkaloids / Q000737:chemistry*; D001483:Base Sequence; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D004247:DNA / Q000032:analysis / Q000737:chemistry / Q000235:genetics; D057927:Hydrophobic and Hydrophilic Interactions
D000470:Alkaloids; D004247:DNA