Modified Bacillus thuringiensis toxins and a hybrid B. thuringiensis strain counter greenhouse-selected resistance in Trichoplusia ni.
Resistance of greenhouse-selected strains of the cabbage looper, Trichoplusia ni, to Bacillus thuringiensis subsp. kurstaki was countered by a hybrid strain of B. thuringiensis and genetically modified toxins Cry1AbMod and Cry1AcMod, which lack helix alpha-1. Resistance to Cry1AbMod and Cry1AcMod was >100-fold less than resistance to native toxins Cry1Ab and Cry1Ac.
Franklin
Michelle T
MT
Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4. franklin@zoology.ubc.ca
Nieman
Christal L
CL
Janmaat
Alida F
AF
Soberón
Mario
M
Bravo
Alejandra
A
Tabashnik
Bruce E
BE
Myers
Judith H
JH
D000818:Animals; D001413:Bacillus thuringiensis / Q000472:pathogenicity*; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000235:genetics / Q000633:toxicity*; D004731:Endotoxins / Q000235:genetics / Q000633:toxicity*; D006460:Hemolysin Proteins / Q000235:genetics / Q000633:toxicity*; D007915:Lepidoptera / Q000187:drug effects*; D007928:Lethal Dose 50; D050505:Mutant Proteins / Q000235:genetics / Q000633:toxicity*; D010572:Pest Control, Biological / Q000379:methods*; D016019:Survival Analysis
D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D004731:Endotoxins; D006460:Hemolysin Proteins; D050505:Mutant Proteins; C030956:insecticidal crystal protein, Bacillus Thuringiensis