[Hormone replacement therapy--growth hormone, melatonin, DHEA and sex hormones].
The ability to maintain active and independent living as long as possible is crucial for the healthy longevity. Hormones responsible for some of the manifestations associated with aging are growth hormone, insulin-like growth factor-1 (IGF-1), melatonin, dehydroepiandrosterone (DHEA), sex hormones and thyroid hormones. These hormonal changes are associated with changes in body composition, visceral obesity, muscle weakness, osteoporosis, urinary incontinence, loss of cognitive functioning, reduction in well being, depression, as well as sexual dysfunction. With the prolongation of life expectancy, both men and women today live the latter third life with endocrine deficiencies. Hormone replacement therapy may alleviate the debilitating conditions of secondary partial endocrine deficiencies by preventing or delaying some aspects of aging.
Fukai
Shiho
S
Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo.
Akishita
Masahiro
M
D000375:Aging / Q000187:drug effects*; D003687:Dehydroepiandrosterone / Q000627:therapeutic use; D005260:Female; D012739:Gonadal Steroid Hormones / Q000627:therapeutic use; D013006:Growth Hormone / Q000627:therapeutic use; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D008297:Male; D008550:Melatonin / Q000627:therapeutic use
D012739:Gonadal Steroid Hormones; D003687:Dehydroepiandrosterone; D013006:Growth Hormone; D008550:Melatonin