title: Aromatase inhibitor for treatment of a recurrent abdominal wall endometrioma in a postmenopausal woman.
abstract: OBJECTIVE
  Treat an abdominal wall endometrioma in a post-menopausal patient.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Academic medical center.
  
  
  METHODS
  A post-menopausal women with a large recurrent abdominal wall endometrioma.
  
  
  METHODS
  The patient was managed with the combination of an aromatase inhibitor, a progestin, and serial cyst aspiration.
  
  
  METHODS
  Serum and cyst estradiol levels as well as sonographic demonstration of resolution.
  
  
  RESULTS
  Serum and cyst estradiol levels were significantly diminished and the cyst diminished in size.
  
  
  CONCLUSIONS
  Taken together, this case demonstrates a novel approach for managing and monitoring medical therapy for unusual clinical presentations of endometriosis. Furthermore, it illustrates that endometriotic implants can be a source of circulating estrogen in postmenopausal women, and that this source of estrogen is generated by increased aromatase activity.
authors: Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut.
authors: Isaac E
authors: IE
authors: Sasson
authors: Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut; Division of Reproductive Endocrinology, Yale University School of Medicine, New Haven, Connecticut. Electronic address: hugh.taylor@yale.edu.
authors: Hugh S
authors: HS
authors: Taylor
mesh_terms: D034861:Abdominal Wall; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000077289:Letrozole; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use*; D017698:Postmenopause; D012008:Recurrence; D013896:Thoracic Diseases / Q000188:drug therapy*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use*
chemical_list: D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077289:Letrozole