[Atypical progressive multifocal leukoencephalopathy (PML) in a patient with pulmonary sarcoidosis].
BACKGROUND
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of central nervous system due to the JC virus. PML generally occurs in immunocompromised hosts and has a fatal outcome.


METHODS
We report a case of an atypical PML in a patient with pulmonary sarcoidosis: MRI showed multifocal and punctate contrast enhancements. The diagnostic was made by brain biopsy.


CONCLUSIONS
The pathophysiology of this association is probably related to the immunodepression induced by sarcoidosis.
Le Guilloux
J
J
Service de neurologie, CHU Avicenne, 125, route de Stalingrad, 93009 Bobigny cedex, France. johanleguilloux@hotmail.fr
Roubiou
C
C
Mallet
J
J
Bouvry
D
D
Alkhalil
A
A
Coman
I
I
Belin
C
C
Gorochov
G
G
Carpentier
A
A
Mokhtari
K
K
Carpentier
A-F
AF
D000328:Adult; D001921:Brain / Q000473:pathology; D003711:Demyelinating Diseases / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000473:pathology