title: Abdominal pain in a patient with ankylosing spondylitis under treatment with infliximab.
abstract: In patients suffering from ankylosing spondylitis, silent inflammatory bowel disease (IBD) is frequent. Furthermore, spondylarthritis may be the first manifestation of IBD.We describe the case of a patient suffering from ankylosing spondylitis who presented with abdominal pain. The patient had been treated over 2(1/2) years with infliximab. Although the initial clinical presentation seemed to suggest new-onset IBD as the cause of the abdominal pain, it eventuated that the patient was suffering from a severe abdominal manifestation of tuberculosis likely due to reactivation of latent tuberculosis by the anti-TNF agent.
authors: Division of Rheumatology and Rehabilitation, Kantonsspital, St. Gallen, Rohrschacherstrasse 95, St. Gallen, Switzerland. julian.cooper@gmx.net
authors: Julian
authors: J
authors: Cooper
authors: Beat
authors: B
authors: Flückiger
authors: Birgit
authors: B
authors: Traichl
authors: Pierre-André
authors: PA
authors: Diener
authors: Petra
authors: P
authors: Otto
authors: Johannes
authors: J
authors: von Kempis
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000069285:Infliximab; D014395:Peritonitis, Tuberculous / Q000150:complications / Q000175:diagnosis*; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000188:drug therapy*; D014385:Tuberculosis, Gastrointestinal / Q000150:complications / Q000175:diagnosis*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab