Hypothalamic amenorrhea in young women with underlying polycystic ovary syndrome.
The purpose of this study was to compare the hormonal/clinical profiles and markers of bone health of women with hypothalamic amenorrhea (HA) to women with suspected HA and underlying polycystic ovary syndrome (PCOS). The results indicate that compared to women with HA, women with HA and underlying PCOS exhibit higher body mass index (BMI), bone mineral densities, and incidence of hyperandrogenism, that they may exhibit increased hyperandrogenism and irregular menses with weight gain, and that they remain at similar risk for osteopenia and osteoporosis.
Sum
Melissa
M
Columbia University Medical Center, New York, New York, USA. ms2452@columbia.edu
Warren
Michelle P
MP
D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000453:epidemiology* / Q000378:metabolism; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000453:epidemiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000453:epidemiology / Q000378:metabolism; D007027:Hypothalamic Diseases / Q000453:epidemiology* / Q000378:metabolism; D015994:Incidence; D010024:Osteoporosis / Q000453:epidemiology* / Q000378:metabolism; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology* / Q000378:metabolism; D012307:Risk Factors; D015430:Weight Gain; D055815:Young Adult
D015415:Biomarkers