[The condition of oxidation-antioxidation balance of kidney and suprarenal tissue in experimental traumatic shock with white rats and the influence of Plaferon LB].
The aim of the work is the study of the oxidation-ant oxidation balance of kidney and suprarenal tissue and the influence on them of Plapherone LB preparation. The objects for experiment were 30 white rats which weigh was about 200gr. The traumatic shock was reproduced according to Kennon. White rats were divided into two groups. In 15 minutes after shock intraperitonealy were made: first group - 0,3 ml of physiologic solution, second group - Plapherone LB 0,06 mg on 0,3 mg of physiologic solution. Separately was studied control group of animals. The tissues were studied by the method of electronic paramagnet resonance on RE-1304 radiometer (Russia). The rough upset of oxidation-antioxidation balance was revealed. The use of Plapherone LB in this case promotes the optimization of these changes.
Nakashidze
I M
IM
Chikovani
T I
TI
Sanikidze
T V
TV
Tsintsadze
N G
NG
D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D007668:Kidney / Q000378:metabolism*; D008297:Male; D009479:Neuropeptides / Q000627:therapeutic use*; D010084:Oxidation-Reduction; D051381:Rats; D012774:Shock, Traumatic / Q000188:drug therapy* / Q000378:metabolism
D000975:Antioxidants; D009479:Neuropeptides; C091912:plaferon