Is there a role of the histologic subtypes of papillary renal cell carcinoma as a prognostic factor?
OBJECTIVE
The aim of this study was to compare type 1 and type 2 papillary renal cell carcinoma (RCC) for validating this subclassification as a prognostic factor.


METHODS
A total of 70 patients with chromophobe RCC were included in the analysis. Patients with papillary RCC were categorized into type 1 (n = 33) and type 2 (n = 37).


RESULTS
The median progression-free survival was 31.0 months for the type 1 group and 12.0 months for the type 2 group (P = 0.001). The median cancer-specific survival was 41.1 months for the type 1 group and 24.0 months for the type 2 group (P = 0.097). Multivariate Cox proportional hazards model for patients with papillary RCC showed that no variables including histologic subtyping were independent predictors of progression-free and cancer-specific survival.


CONCLUSIONS
In the present study, the type of papillary RCC does not reach independent prognostic significance.
Ku
Ja Hyeon
JH
Department of Urology, Seoul National University Hospital, Jongno Ku, Seoul, Korea.
Moon
Kyung Chul
KC
Kwak
Cheol
C
Kim
Hyeon Hoe
HH
Lee
Sang Eun
SE
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis