title: Correction of tear trough deformity with novel porcine collagen dermal filler (Dermicol-P35).
abstract: Deformity of the tear trough region, which can occur during the aging process, can result in dark shadows under the eyes and a fatigued appearance. Augmentation of the tear trough is challenging because of the thin skin and lack of fat in the region. Adding volume to the tear trough region with a dermal filler is a nonsurgical procedure with minimal discomfort to the patient. Dermicol-P35 (Evolence; Ortho Dermatologics, Skillman, NJ) is a new, ribose crosslinked, highly purified, porcine-based collagen filler that does not require prior skin testing and has shown improved persistence compared with bovine collagen-based dermal fillers. In this article, we present the clinical outcomes of patients who have received treatment with a novel ribose crosslinked porcine collagen dermal filler for the correction of tear trough deformity.
authors: Skin Laser and Surgery Specialists of New York and New Jersey, New York, NY 10022-2184, USA. drdavidgoldberg@skinandlasers.com
authors: David J
authors: DJ
authors: Goldberg
mesh_terms: D000328:Adult; D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D003257:Consumer Product Safety; D003357:Cosmetic Techniques; D003432:Cross-Linking Reagents / Q000737:chemistry; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D005143:Eyelids; D005260:Female; D006031:Glycosylation; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D012060:Rejuvenation; D012266:Ribose / Q000737:chemistry; D015595:Skin Aging; D013552:Swine; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D003879:Dermatologic Agents; C530016:dermicol-P35 30G; D012266:Ribose; D003094:Collagen