title: Bilateral allergic fungal rhinosinusitis caused by Schizophillum commune and Aspergillus niger. A case report.
abstract: Schizophillum commune (S. commune) is a rare type of basidiomycetous fungus that has being reported as a cause of allergic fungal rhinosinusitis (AFRS), invasive type of fungal sinusitis and allergic bronchopulmonary mycosis (ABPM). However, it is believed that S. commune was often misdiagnosed to Aspergillus sp. We report a case of bilateral nasal polyps and maxillary, ethmoidal and sphenoidal involvement within the context of S. commune and Aspergillus niger associated AFRS. Our patient was suffering from a chronic disease with periods of remission and exacerbation and was treated successfully by a combination of surgical and antifungal treatment. In our experience, S. commune may be found frequently in patients with AFRS. AFRS, including the S. commune-associated type, usually runs a prolonged course and can affect any paranasal sinus. Surgical treatment alone is not sufficient and must be combined with medical treatment.
authors: Department of Otorhinolaryngology, Head & Neck Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. khalifa369@yahoo.com
authors: Mohamed Khalifa
authors: MK
authors: Ahmed
authors: Takashi
authors: T
authors: Ishino
authors: Sachio
authors: S
authors: Takeno
authors: Katsuhiro
authors: K
authors: Hirakawa
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001234:Aspergillus niger / Q000302:isolation & purification / Q000472:pathogenicity*; D003131:Combined Modality Therapy; D004724:Endoscopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012220:Rhinitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012567:Schizophyllum / Q000302:isolation & purification / Q000472:pathogenicity*; D012852:Sinusitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents