Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases.
Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy.
Freitas
Vinicius Antunes
VA
MD, specialization student on Otorhinolaryngology at Núcleo de Otorrino BH.
Becker
Helena Maria Gonçalves
HMG
PhD, Adjunct Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School.
Guimarães
Roberto Eustáquio Santos
RES
PhD, Adjunct Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School.
Franco
Letícia Paiva
LP
Specialist on Otorhinolaryngology, ENT at Hospital das Clínicas da UFMG.
Guimarães
Fernando Fernandes
FF
Specialist on Otorhinolaryngology, Otorhinolaryngologist.
Martins
Marcelo Figueredo
MF
MD, Resident on General Practice.
Crosara
Paulo Fernando Tormin
PFT
PhD, Substitute Professor in the Department of Otorhinolaryngology, Ophthalmology, and Speech and Hearing Therapy at the UFMG Medical School. ENT Service of the Hospital das Clínicas da Universidade Federal de Minas Gerais.
D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy