title: Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions.
abstract: OBJECTIVE
  The study goals were development of reference intervals and an interpretive algorithm for pancreatic cyst fluid tumor markers.
  
  
  METHODS
  442 pancreatic cyst fluids were tested for CEA, CA19-9, and amylase.
  
  
  RESULTS
  CEA>30 ng/mL discriminates mucinous from non-mucinous cysts. After CEA analysis, amylase and CA19-9 segregate non-mucinous and mucinous subtypes, respectively.
  
  
  CONCLUSIONS
  Pancreatic cyst fluid tumor markers supplement other diagnostic measures. This study provides estimated reference intervals and an algorithm for interpretation.
authors: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. snozek.christine@mayo.edu
authors: Christine L H
authors: CL
authors: Snozek
authors: Ranjan C
authors: RC
authors: Mascarenhas
authors: Dennis J
authors: DJ
authors: O'Kane
mesh_terms: D000465:Algorithms; D000681:Amylases / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis; D018395:CA-19-9 Antigen / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D020420:Cyst Fluid / Q000737:chemistry*; D003937:Diagnosis, Differential; D010181:Pancreatic Cyst / Q000473:pathology*; D012372:ROC Curve; D012016:Reference Values
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen; D000681:Amylases