title: From discovery to production: scale-out of continuous flow meso reactors.
abstract: A continuous flow parallel reactor system has been developed to provide a rapid and seamless transition from the discovery phase and production phase of chemical synthesis, particularly in low volume-high value pharmaceuticals production. Using a single fixed bed catalytic meso reactor, reactions can be screened on a small discovery scale over short time scales. The intensified process produces sufficient material for a full analysis. By replication of the single reactor in parallel, the same chemistry can be achieved on a larger scale, on a small footprint and without the mass and heat transport limitations of reactor scale-out in batch.
authors: Department of Chemical & Process Engineering, The University of Sheffield, Mappin Street, Sheffield S1 3JD, United Kingdom.
authors: Peter
authors: P
authors: Styring
authors: Ana I R
authors: AI
authors: Parracho