title: [An autopsy case of pulmonary tumor thrombotic microangiopathy complicated with interstitial pneumonia and lipoid pneumonia].
abstract: A 67-year-old woman was admitted to our hospital because of progressive dyspnea, cough, bloody sputum, and backache. Chest radiography and CT scans showed bilateral diffuse interstitial shadows, bilateral pleural effusion and dilatation of the pulmonary artery. Echocardiography indicated pulmonary hypertension, and the serum tumor marker levels were elevated. We performed right cardiac catheterization, and withdrew some blood from a pulmonary artery catheter in the wedge position. We confirmed moderate pulmonary hypertension, and adenocarcinoma-like malignant cells were seen in the aspirated blood. The patient died of progressive respiratory failure despite supportive care. In addition to PTTM and lymphangiosis carcinomatosa, autopsy of the right lung revealed interstitial pneumonia and lipoid pneumonia, both of which were not reported before to be associated with PTTM.
authors: Department of Respiratory Medicine, National Hospital Organization Ibarakihigashi National Hospital.
authors: Kyoko
authors: K
authors: Ota
authors: Masashi
authors: M
authors: Matsuyama
authors: Nariaki
authors: N
authors: Kokuho
authors: Hironori
authors: H
authors: Masuko
authors: Hiroki
authors: H
authors: Hayashi
authors: Takashi
authors: T
authors: Iizuka
authors: Kenji
authors: K
authors: Hayashibara
authors: Takefumi
authors: T
authors: Saito
authors: Yoshinori
authors: Y
authors: Kawabata
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications*; D008175:Lung Neoplasms / Q000473:pathology*; D008833:Microcirculation; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011017:Pneumonia, Lipid / Q000150:complications*; D011655:Pulmonary Embolism / Q000628:therapy*; D013927:Thrombosis / Q000473:pathology*