Effect of chain length of alcohol on the lipase-catalyzed esterification of propionic acid in supercritical carbon dioxide.
The esterification of propionic acid was investigated using three different alcohols, namely, isopropyl alcohol, isobutyl alcohol, and isoamyl alcohol. The variation of conversion with time for the synthesis of isoamyl propionate was investigated in the presence of five enzymes. Novozym 435 showed the highest activity, and this was used as the enzyme for investigating the various parameters that influence the esterification reaction. The Ping-Pong Bi-Bi model with inhibition by both acid and alcohol was used to model the experimental data and determine the kinetics of the esterification reaction.
Varma
Mahesh N
MN
Department of Chemical Engineering, Indian Institute of Science, Bangalore, 560012, India.
Madras
Giridhar
G
D019840:2-Propanol / Q000737:chemistry*; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D000440:Butanols / Q000737:chemistry*; D002245:Carbon Dioxide / Q000737:chemistry*; D004800:Enzymes, Immobilized / Q000378:metabolism; D004951:Esterification; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D005656:Fungal Proteins; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism; D008049:Lipase / Q000235:genetics / Q000378:metabolism*; D008956:Models, Chemical; D000439:Pentanols / Q000737:chemistry*; D011422:Propionates / Q000138:chemical synthesis / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D001426:Bacterial Proteins; D000440:Butanols; D004800:Enzymes, Immobilized; D004952:Esters; D005656:Fungal Proteins; D007527:Isoenzymes; D000439:Pentanols; D011422:Propionates; D012997:Solvents; D002245:Carbon Dioxide; C040507:isobutyl alcohol; C029683:isopentyl alcohol; C093667:Novozyme 435; D008049:Lipase; D019840:2-Propanol