title: Use of biomaterials with or without platelet-rich plasma in postextraction sites: a microscopic study in dogs.
abstract: OBJECTIVE
  Sites that will receive dental implants need to be quantitatively and qualitatively suitable for this therapy. The treatment of postextraction areas with biomaterials associated with platelet-rich plasma (PRP) might make the repair process more efficient, resulting in desirable bone characteristics. The present study sought to evaluate the effectiveness of PRP in the process of new bone formation when associated with biomaterials.
  
  
  METHODS
  Four female dogs were used for this study. Mandibular postextraction sites received implants, along with bone substitutes (Bio-Oss [BO] or Biogran [BG]), on the right side of the mandible and these biomaterials plus PRP on the left side of the mandible. Thirty days later, the tissues were prepared and histologic analyses were carried out to compare the repair processes.
  
  
  RESULTS
  PRP accelerated the repair process for both BO and BG; however, the action of PRP associated with BO did not surpass that of BG alone.
  
  
  CONCLUSIONS
  The addition of PRP appears to accelerate the repair process.
authors: Division of Oral and Maxillofacial Surgery, Academy of Dentistry, State University of Maringá, Paraná, Brazil. edevaldocamarini@wnet.com.br
authors: Edevaldo Tadeu
authors: ET
authors: Camarini
authors: Jacqueline Nelisis
authors: JN
authors: Zanoni
authors: Pablo Cornelius Comelli
authors: PC
authors: Leite
authors: Fernanda Brasil Daura Jorge
authors: FB
authors: Boos
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D018786:Bone Substitutes; D004285:Dogs; D005260:Female; D005898:Glass; D008903:Minerals; D018919:Neovascularization, Physiologic; D053657:Platelet-Rich Plasma; D020390:Tooth Socket / Q000601:surgery*
chemical_list: C077540:Bio-Oss; D001672:Biocompatible Materials; C073544:Biogran; D018786:Bone Substitutes; D008903:Minerals