Primary dedifferentiated chondrosarcoma of the lung.
Extraskeletal dedifferentiated chondrosarcomas (DC) are uncommon tumors that predominantly occur in the head and neck. Herein, we describe a case of pulmonary DC detected in a patient with systemic sclerosis and presenting with a symptomatic large pleural effusion and a pulmonary lobar consolidation on chest imaging. To the best of our knowledge, this is the first report of pulmonary chondrosarcoma involving the pleura and occurring in association with systemic sclerosis. Moreover, this is the second report of a dedifferentiated variant among all reported cases of primary lung chondrosarcoma.
Boueiz
Adel
A
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. aelboue1@jhmi.edu
Abougergi
Marwan S
MS
Noujeim
Carlos
C
Bousamra
Alexis
A
Sfeir
Pierre
P
Zaatari
Ghazi
G
Bou-Khalil
Pierre
P
D002813:Chondrosarcoma / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008875:Middle Aged; D010994:Pleura / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D012595:Scleroderma, Systemic / Q000150:complications