Highly asymmetric cobalt-catalyzed aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3).
A Co(II)-based catalytic system has been developed for asymmetric aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3) under mild conditions, forming the corresponding N-Tces-aziridines in high yields and excellent enantioselectivities.
Subbarayan
Velusamy
V
Department of Chemistry, University of South Florida, Tampa, FL 33620-5250, USA.
Ruppel
Joshua V
JV
Zhu
Shifa
S
Perman
Jason A
JA
Zhang
X Peter
XP
D000475:Alkenes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*
D000475:Alkenes; D001386:Azides; D001388:Aziridines; C543266:trichloroethoxysulfonyl azide; D003035:Cobalt