[Medical applications of systems biology].
We illustrate in this review some applications of systems biology in the medical and biological areas. After a brief summary of time scales experienced by medical -observations and of the general scheme of dynamic systems, we describe how some techniques underlying the complex systems theory can be applied to model medical issues in immunology, medical genetics, developmental morphogenesis, biochemistry, epidemiology, telemedecine and multiple platforms of expertise. In concluding, we will discuss the issue of "clinomics" coupling clinical and -omics data in a unique patient-specific file.
Demongeot
Jacques
J
TIMC-IMAG UMR UJF/CNRS 5525, Université J. Fourier de Grenoble, Faculté de médecine, 38700 La Tronche, France. jacques.demongeot@imag.fr
D004194:Disease / Q000235:genetics; D004777:Environment; D044127:Epigenesis, Genetic / Q000235:genetics; D023281:Genomics; D006801:Humans; D010788:Photosynthesis / Q000502:physiology; D018521:Plant Physiological Phenomena; D049490:Systems Biology / Q000379:methods* / Q000639:trends