"Self"-reflection by KIR.
Significant debate exists over the proposed mechanisms by which NK receptor expression coordinates with the acquisition of function and titration of responsiveness, a process called NK-cell education. In this issue of Blood, Andersson and colleagues provide new insights into the mechanisms underlying NK-cell repertoire formation and the modulation of NK-cell function.
Cooley
Sarah
S
University of Minnesota, Minnesota, USA.
Miller
Jeffrey S
JS