Polyarthritis with chondronecrosis associated with osteonecrosis, panniculitis and pancreatitis.
Arthritis associated with panniculitis complicating pancreatitis is well described in the literature, usually associated with osteonecrosis. Chondronecrosis has not been reported before in association with pancreatitis. We report a patient with chronic pancreatitis who presented with polyarthritis, panniculitis, osteonecrosis, but in addition had clear evidence of chondronecrosis. We suggest that direct extension of noxious materials from nearby subchondral osteonecrotic bone lesion could be the cause of the osteonecrosis and one of the pathological mechanisms leading to arthritis in patients with pancreatitis.
Mustafa
Khader N
KN
Division of Rheumatology, Department of Internal Medicine, Jordan University Hospital, Amman, Jordan. kmustafa@ju.edu.jo
Hadidy
Azmy
A
Shoumaf
Maha
M
Razzuki
Shams A
SA
D001168:Arthritis / Q000150:complications* / Q000209:etiology; D001847:Bone Diseases / Q000150:complications; D017809:Fatal Outcome; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010020:Osteonecrosis / Q000150:complications*; D010195:Pancreatitis / Q000150:complications*; D050500:Pancreatitis, Chronic / Q000150:complications; D015434:Panniculitis / Q000150:complications* / Q000209:etiology