Alternethanoxins A and B, polycyclic ethanones produced by Alternaria sonchi , potential mycoherbicides for Sonchus arvensis biocontrol.
Alternaria sonchi is a fungal pathogen isolated from Sonchus arvensis and proposed as a biocontrol agent of this noxious perennial weed. Different phytotoxic metabolites were isolated from solid culture of the fungus. Two new polycyclic ethanones, named alternethanoxins A and B, were characterized using essentially spectroscopic and chemical methods. Tested by leaf disk-puncture assay on the fungal host plant and a number of nonhost plants, alternethanoxins A and B were shown to be phytotoxic, whereas they did not possess antimicrobial activity tested at 100 microg/disk. Hence, alternethanoxins A and B have potential as nonselective natural herbicides. Some structure-activity relationship observations were also made.
Evidente
Antonio
A
Dipartimento di Scienze del Suolo, della Pianta, dell'Ambiente e delle Produzioni Animali, Universita di Napoli Federico II, Via Universita 100, 80055 Portici, Italy.
Punzo
Biancavaleria
B
Andolfi
Anna
A
Berestetskiy
Alexander
A
Motta
Andrea
A
D000528:Alternaria / Q000737:chemistry / Q000378:metabolism*; D006540:Herbicides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D009183:Mycotoxins / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D010572:Pest Control, Biological; D011083:Polycyclic Compounds / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D031184:Sonchus / Q000187:drug effects*
D006540:Herbicides; D009183:Mycotoxins; D011083:Polycyclic Compounds