Polyethylenimine effectively induces, stabilizes, and regulates intramolecular G-quadruplexes.
The interaction between polyethylenimine (PEI) and telomeric DNA was studied. The results demonstrated that PEI could effectively induce, stabilize, and regulate intramolecular G-quadruplexes. The mechanism for these results has been discussed, and was estimated to be condensation effect of PEI.
Sun
Hongxia
H
Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
Zhou
Qiuju
Q
Xiang
Junfeng
J
Tang
Yalin
Y
D002942:Circular Dichroism; D054856:G-Quadruplexes; D006801:Humans; D011094:Polyethyleneimine / Q000737:chemistry*; D044366:Transition Temperature
D011094:Polyethyleneimine