title: New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus).
abstract: An enterovirus was cultured from an erosive tongue lesion of a bottlenose dolphin (Tursiops truncatus). The morphology of virions on negative staining electron microscopy was consistent with those of enteroviruses. Analysis of 2613 bp of the polyprotein gene identified the isolate as a novel enterovirus strain, tentatively named bottlenose dolphin enterovirus (BDEV), that nests within the species Bovine enterovirus. Serologic evidence of exposure to enteroviruses was common in both free-ranging and managed collection dolphins. Managed collection dolphins were more likely to have high antibody levels, although the highest levels were reported in free-ranging populations. Associations between enterovirus antibody levels, and age, sex, complete blood counts, and clinical serum biochemistries were explored. Dolphins with higher antibody levels were more likely to be hyperproteinemic and hyperglobulinemic.
authors: College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA. NollensH@mail.vetmed.ufl.edu
authors: Hendrik H
authors: HH
authors: Nollens
authors: Rebecca
authors: R
authors: Rivera
authors: Gustavo
authors: G
authors: Palacios
authors: James F X
authors: JF
authors: Wellehan
authors: Jeremiah T
authors: JT
authors: Saliki
authors: Shannon L
authors: SL
authors: Caseltine
authors: Cynthia R
authors: CR
authors: Smith
authors: Eric D
authors: ED
authors: Jensen
authors: Jeffrey
authors: J
authors: Hui
authors: W Ian
authors: WI
authors: Lipkin
authors: Pamela K
authors: PK
authors: Yochem
authors: Randall S
authors: RS
authors: Wells
authors: Judy
authors: J
authors: St Leger
authors: Stephanie
authors: S
authors: Venn-Watson
mesh_terms: D000818:Animals; D050681:Bottle-Nosed Dolphin / Q000821:virology*; D004769:Enterovirus Infections / Q000662:veterinary*; D029650:Enterovirus, Bovine / Q000235:genetics / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D008969:Molecular Sequence Data; D010802:Phylogeny; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014059:Tongue / Q000821:virology