title: Earlier diagnosis and treatment of symptomatic bowel cancer: can it be achieved and how much will it improve survival?
abstract: OBJECTIVE
  To determine current delays in diagnosis and treatment of bowel cancer, when and why they occur, and what effect they have on survival.
  
  
  METHODS
  A detailed review of the literature based on the development of the GP referral guidelines in 2000.
  
  
  RESULTS
  There is no evidence of a reduction in the delay to diagnosis and treatment of bowel cancer over the last 60 years. There is no strong theoretical basis for a benefit from earlier diagnosis of symptomatic bowel cancer and this is consistent with observational studies.
  
  
  CONCLUSIONS
  Campaigns to earlier diagnose bowel cancer will not be successful unless new strategies are developed. There is substantial evidence that earlier diagnosis of symptomatic bowel cancer will not improve survival in the majority of patients. However as excessive delays still occur in some patients it is reasonable to continue to aim to diagnose and treat all bowel cancer within 6 months of the onset of symptoms with an overall median of 3-4 months.
authors: Department of Surgery, Queen Alexandra Hospital, Portsmouth, UK. karen.flashman@porthosp.nhs.uk
authors: M R
authors: MR
authors: Thompson
authors: I
authors: I
authors: Heath
authors: E T
authors: ET
authors: Swarbrick
authors: L Faulds
authors: LF
authors: Wood
authors: B G
authors: BG
authors: Ellis
mesh_terms: D042241:Early Diagnosis; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D011787:Quality of Health Care; D012017:Referral and Consultation; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D006113:United Kingdom; D014850:Waiting Lists