title: Synthesis, spectral and biological studies of nitrogen-sulphur donor macrocyclic ligands and their transition metals complexes.
abstract: Mn(II), Co(II), Ni(II) and Cu(II) complexes have been synthesized with 22 and 24 membered tetramide macrocyclic ligands viz; 1,9,12,20-tetraaza-2,8,13,19-tetraone-5,16-dithiacyclodocosane [L(1)] and 1,9,13,21-tetraaza-2,8,14,20-tetraone-5,17-dithiacyclotetracosane [L(2)] and characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, mass, IR, electronic EPR spectral studies and electrochemical properties. The molar conductance of all the complexes in DMSO solution is corresponding to 1:2 electrolyte. Thus these complexes may be formulated as [M(L')]Cl(2) [where M = Mn(II), Co(II), Ni(II) and Cu(II) L' = L(1) and L(2)]. On the basis of spectral studies a distorted octahedral geometry has been assigned for all the complexes. The ligands and their complexes were also screened in vitro against two pathogenic fungi (F. moniliformae and R. solani) to assess their growth inhibiting potential.
authors: Department of Chemistry, Zakir Husain College (University of Delhi), J.L.N. Marg, New Delhi-110002, India. shweta verma1@rediffmail.com
authors: Shweta
authors: S
authors: Verma
authors: Sulekh
authors: S
authors: Chandra
authors: Usha
authors: U
authors: Dev
authors: Nidhi
authors: N
authors: Joshi
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D005670:Fusarium / Q000187:drug effects; D008024:Ligands; D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D012232:Rhizoctonia / Q000187:drug effects; D013057:Spectrum Analysis; D028561:Transition Elements / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D008024:Ligands; D047028:Macrocyclic Compounds; D028561:Transition Elements