[Neuroplasticity in patients with implant supported full dentures].
OBJECTIVE
To investigate the potential mechanism of "osseoperception" which is the sensory and motor experience associated with dental implants.


METHODS
Twenty patients with implant supported full dentures or traditional full dentures were recruited in this study. Functional MRI (fMRI) scan covering the whole brain was carried out in these patients in clenching. The fMRI data were analyzed with SPM 99 software.


RESULTS
In implant supported removable denture group, increased blood oxygen level dependent (BOLD) signals during clenching were found in prefrontal cortex, premotor cortex, superior parietal cortex, basal ganglion and thalamus. In implant supported fixed denture group, main activations were found in prefrontal cortex, primary sensory and motor cortex, Broca's area, premotor cortex, superior temporal cortex, insular, basal ganglion, thalamus and hippocampus. In traditional full denture group, significant activations were mainly found in prefrontal cortex, premotor cortex. Their activation maps showed the greatest individually dependent diversity.


CONCLUSIONS
Sensory and motor feedback of central nervous system in patients with implant support fixed dentures is close to that of natural dentition. Mastication with traditional full dentures is more likely a process of task learning, memory and adaptation, which might be a more individually dependent restoration.
Chen
Yan
Y
Center of Dental Implantation, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Lin
Ye
Y
Li
Ke
K
Li
Jian-hui
JH
DI
Ping
P
Jin
Zhen
Z
D000368:Aged; D002540:Cerebral Cortex / Q000502:physiology*; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D003824:Denture, Complete; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009473:Neuronal Plasticity
D015921:Dental Implants