title: In vitro genotoxicity of Settat town landfill leachate, Morocco.
abstract: With the increasing use of landfill sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O2, chemical oxygen demand (COD), HCO3(-), Ca2+, Mg2+, Cl(-), and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan standard. Increased micronucleus frequencies were also found for both leachate and well water. Preliminary results indicate that both types of water are genotoxic and pose environmental and human health risk.
authors: Agrofood and Health Laboratory, Faculty of Science and Technology, University Hassan I, Settat, Morocco.
authors: Loubna
authors: L
authors: Amahdar
authors: Abdellah
authors: A
authors: Anouar
authors: Bouchra
authors: B
authors: Ababou
authors: Luc
authors: L
authors: Verschaeve
authors: Abderraouf
authors: A
authors: Hilali
mesh_terms: D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D007962:Leukocytes / Q000187:drug effects; D015162:Micronucleus Tests; D009018:Morocco; D009152:Mutagenicity Tests; D012037:Refuse Disposal; D012989:Soil Pollutants / Q000737:chemistry / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D012989:Soil Pollutants; D014874:Water Pollutants, Chemical