title: Zirconium-mediated selective synthesis of 1,2,4,5-tetrasubstituted benzenes from two silyl-substituted alkynes and one internal alkyne.
abstract: Selective synthesis of 1,2,4,5-tetrasubstituted benzenes was achieved via formation of 2,5-bis(trimethylsilyl)zirconacyclopentadienes from 2 equiv of TMS-substituted alkynes with Cp(2)ZrBu(2) and Cu-mediated formation of 1,4-disilylbenzene by cycloaddition of zirconacyclopentadienes to disubstituted alkynes. Preparation of 1,2,3,4,9,10-hexasubstituted pentacene and 2,3,6,11-tetrasubstituted naphthacene derivatives were demonstrated by a homologation or coupling method using tetrasubstituted benzene.
authors: Catalysis Research Center, Hokkaido University, and SORST, Japan Science and Technology Agency, Kita-ku, Sapporo 001-0021, Japan.
authors: Shi
authors: S
authors: Li
authors: Hongmei
authors: H
authors: Qu
authors: Lishan
authors: L
authors: Zhou
authors: Ken-ichiro
authors: K
authors: Kanno
authors: Qiaoxia
authors: Q
authors: Guo
authors: Baojian
authors: B
authors: Shen
authors: Tamotsu
authors: T
authors: Takahashi