Leptin as clinical target.
PLeptin is an adipocyte-derived hormone with pleiotropic effects on energy homeostasis, endocrine and reproductive functions, and immune responses. The multiple actions of leptin have led to the design and development of several leptin-based approaches to modulate the metabolic and endocrine status, to reduce inflammation, and to improve immune responses. Here, we review the current patents on leptin in different clinic applications.
Cai
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Department of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.
Shi
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Matarese
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La Cava
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D000818:Animals; D032701:Biomimetics; D015316:Genetic Therapy; D006801:Humans; D007154:Immune System Diseases / Q000188:drug therapy*; D007114:Immunization; D007246:Infertility / Q000188:drug therapy; D020738:Leptin / Q000627:therapeutic use*; D008659:Metabolic Diseases / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy; D010330:Patents as Topic
D020738:Leptin