Protein and carbohydrate supplementation after exercise increases plasma volume and albumin content in older and young men.
This study examined whether increased plasma volume (PV) and albumin content (Alb(cont)) in plasma for 23 h after exercise were attenuated in older subjects compared with in young adult subjects, and if this attenuation abated by supplementation with protein and carbohydrate (CHO) immediately after exercise. Eight moderately active older (approximately 68 yr) and 8 young (approximately 21 yr) men performed two trials: control (CNT) and Pro-CHO in which subjects consumed placebo (0.5 kcal, 0 g protein, 0.5 mg Na(+) in 3.2 ml total fluid volume/kg body wt) or protein and CHO mixture (3.2 kcal, 0.18 g protein, 0.5 mg Na(+) in 3.2 ml total fluid volume/kg body wt) supplementations, respectively, immediately after high-intensity interval exercise for 72 min [8 sets of 4 min at 70-80% peak oxygen consumption rate (Vo(2peak)) intermitted by 5 min at 20% Vo(2peak)]. PV, Alb(cont), and plasma globulin content (Glb(cont)) were measured before exercise, at the end of exercise, every hour from the 1st to the 5th hour after exercise, and at the 23rd hour after exercise. From 12 h before the start to the end of experiment, food intake was controlled to the age-matched recommended dietary allowances. We found that during the first 4 h after exercise in CNT, Alb(cont) recovered less in the older than the young group by approximately 0.04 g/kg (P < 0.05), while it generally recovered more with Pro-CHO than CNT by approximately 0.09 and approximately 0.04 g/kg in the young and older group, respectively, accompanied by a greater increase in PV by approximately 1 and approximately 2 ml/kg, respectively, during the 23 h after exercise (P < 0.05). Glb(cont) remained constant throughout the experiment in both trials for both age groups. Thus the attenuated responses of Alb(cont) and PV after exercise in older subjects were restored by protein and CHO supplementation immediately after exercise, similarly to young subjects.
Okazaki
Kazunobu
K
Department of Sports Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Hayase
Hideki
H
Ichinose
Takashi
T
Mitono
Hiroyuki
H
Doi
Tatsuya
T
Nose
Hiroshi
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D015308:Anaerobic Threshold / Q000502:physiology; D001642:Bicycling / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001835:Body Weight / Q000187:drug effects / Q000502:physiology; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D004044:Dietary Proteins / Q000494:pharmacology*; D019587:Dietary Supplements; D002149:Energy Intake / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005934:Glucagon / Q000378:metabolism; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D010953:Plasma Volume / Q000187:drug effects* / Q000502:physiology*; D012709:Serum Albumin / Q000378:metabolism*; D014563:Urodynamics / Q000187:drug effects / Q000502:physiology; D014882:Water-Electrolyte Balance / Q000187:drug effects / Q000502:physiology; D055815:Young Adult
D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D012709:Serum Albumin; D005934:Glucagon