Peripheral T-cell lymphomas.
Peripheral T-cell lymphomas (PTCLs) are malignancies of immunologically mature T-cells that arise in peripheral lymphoid tissues such as lymph nodes, spleen, gastrointestinal tract, and skin. These lymphomas are uncommon as compared with the incidence of B-cell lymphomas, and they comprise only 5% to 10% of non-Hodgkin lymphomas in North America and Western Europe. A variety of specific disease entities have been recognized among PTCLs, and they tend to have lymph node, extranodal/cutaneous, or mixed leukemic/lymphomatous presentations. Most PTCLs have an aggressive clinical course. The clinicopathologic features of the various PTCLs are described herein.
Macon
William R
WR
Mayo College of Medicine, Rochester, MN 55905, USA. macon.william@mayo.edu
D003937:Diagnosis, Differential; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology; D016411:Lymphoma, T-Cell, Peripheral / Q000145:classification / Q000175:diagnosis* / Q000378:metabolism; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D012867:Skin / Q000276:immunology / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*; D014944:World Health Organization
D011948:Receptors, Antigen, T-Cell