title: [Bone mineral density, PCB, PCQ and PCDF in Yusho].
abstract: We measured bone mineral density of the distal end of radius with dual energy X-ray absorptiometry, serum cross-linked N-telopeptides of type I collagen, serum bone-specific alkaline phosphatase, serum Ca, serum P, blood PCB level, blood PCQ level and blood PCDF level in Yusho. As a result, the osteoporosis group (< 70% of the young adult mean [YAM] bone mineral density [BMD]) was observed in 7.1% of the studied male subjects. And, the moderate group (> or = 70% and < 80% of YAM BMD), 16.1%, the normal (> or = 80% of YAM BMD) group was 76.8%. Also, 42.3% of all female tested subjects observed in osteoporosis group. The moderate group, 19.2%, the normal group was 38.5%. There was no difference in PCB blood level, PCQ, PCDF for men and women in osteoporosis group, moderate group, and in the normal group. Serum cross-linked N-telopeptides of type I collagen increased in the male osteoporosis group, but serum bone-specific alkaline phosphatase did not change. This study was inconclusive since the results did not determine the influence that PCB, PCQ, PCDF gave to bone density and bone metabolism.
authors: Department of Health Sciences, Graduate School of Biomedical Sciences, Nagasaki University.
authors: Toshiro
authors: T
authors: Yoshimura
authors: Jiro
authors: J
authors: Nakano
authors: Tomoko
authors: T
authors: Masuda
authors: Masahiro
authors: M
authors: Tokuda
authors: Atsushi
authors: A
authors: Sakakibara
authors: Hideki
authors: H
authors: Kataoka
authors: Minoru
authors: M
authors: Okita
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001572:Benzofurans / Q000097:blood*; D015519:Bone Density; D002722:Chlorobenzenes / Q000097:blood*; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins / Q000506:poisoning*; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D005506:Food Contamination; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000097:blood; D011078:Polychlorinated Biphenyls / Q000097:blood* / Q000506:poisoning*
chemical_list: D001572:Benzofurans; D002722:Chlorobenzenes; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins; D004785:Environmental Pollutants; C022053:polychlorinated quaterphenyls; D011078:Polychlorinated Biphenyls