Competition between cleavage and decarboxylation in photolysis of alpha-carboxy-2-nitrobenzyl protected cysteine derivatives.
Photolysis of model peptides containing alpha-carboxy-2-nitrobenzyl (CNB) or alpha-carboxy-4,5-dimethoxy-2-nitrobenzyl (CDMNB) protected cysteines in aqueous solution gives the expected 2-nitrobenzyl-type photocleavage and can be accompanied by photodecarboxylation depending on structural aspects.
Kotzur
Nico
N
Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, 13125 Berlin, Germany.
Briand
Benoît
B
Beyermann
Michael
M
Hagen
Volker
V
D000107:Acetylation; D000595:Amino Acid Sequence; D002264:Carboxylic Acids / Q000737:chemistry*; D003545:Cysteine / Q000737:chemistry*; D009578:Nitrobenzenes / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry; D010782:Photolysis
D002264:Carboxylic Acids; D009578:Nitrobenzenes; D009842:Oligopeptides; C036077:nitrobenzene; D003545:Cysteine