title: Isoplatensimycin: Synthesis and biological evaluation.
abstract: Isoplatensimycin, a novel analog of platensimycin, was synthesized via intramolecular dipolar cycloaddition of a carbonyl ylide. Isoplatensimycin showed little activities against strains of Staphylococcus aureus, but exhibited activities against some vancomycin-resistant enteroccoci.
authors: Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Republic of Korea.
authors: Ki Po
authors: KP
authors: Jang
authors: Chan Hyuk
authors: CH
authors: Kim
authors: Seong Wook
authors: SW
authors: Na
authors: Hiyoung
authors: H
authors: Kim
authors: Heonjoong
authors: H
authors: Kang
authors: Eun
authors: E
authors: Lee
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D062365:Aminobenzoates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000813:Anilides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D016983:Enterococcus / Q000187:drug effects; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D020713:Vancomycin Resistance
chemical_list: D062365:Aminobenzoates; D000813:Anilides; D000900:Anti-Bacterial Agents; C543962:isoplatensimycin; D000218:Adamantane; C510909:platensimycin