title: Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia.
abstract: Baccharis dracunculifolia is the source of Brazilian green propolis (BGP). Considering the broad spectrum of biological activities attributed to green proplis, B. dracunculifolia has a great potential for the development of new cosmetic and pharmaceutical products. In this work, the cultivation of 10 different populations of native B. dracunculifolia had been undertaken aiming to determine the role of seasonality on its phenolic compounds. For this purpose, fruits of this plant were collected from populations of 10 different regions, and 100 individuals of each population were cultivated in an experimental area of 1800 m(2). With respect to cultivation, the yields of dry plant, essential oil and crude extract were measured monthly resulting in mean values of 399 ± 80 g, 0.6 ± 0.1% and 20 ± 4%, respectively. The HPLC analysis allowed detecting seven phenolic compounds: caffeic acid, ferulic acid, aromadendrin-4'-methyl ether (AME), isosakuranetin, artepillin C, baccharin and 2-dimethyl-6-carboxyethenyl-2H-1-benzopyran acid, which were the major ones throughout the 1-year monthly analysis. Caffeic acid was detected in all cultivated populations with mean of 4.0%. AME displayed the wide variation in relation to other compounds showing means values of 0.65 ± 0.13% at last quarter. Isosakuranetin and artepillin C showed increasing concentrations with values between 0% and 1.4% and 0% and 1.09%, respectively. The obtained results allow suggesting that the best time for harvesting this plant, in order to obtain good qualitative and quantitative results for these phenolic compounds, is between December and April.
authors: Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café, s/n, 14040-903, Ribeirão Preto, Brazil.
authors: João Paulo B
authors: JP
authors: de Sousa
authors: Mateus F
authors: MF
authors: Leite
authors: Renata F
authors: RF
authors: Jorge
authors: Dimas O
authors: DO
authors: Resende
authors: Ademar A
authors: AA
authors: da Silva Filho
authors: Niege A J C
authors: NA
authors: Furtado
authors: Ademilson E E
authors: AE
authors: Soares
authors: Augusto C C
authors: AC
authors: Spadaro
authors: Pedro Melillo
authors: PM
authors: de Magalhães
authors: Jairo K
authors: JK
authors: Bastos