Familial Behçet's disease.
Behçet's disease (BD) is a multisystemic vasculitis syndrome characterized by a course of remissions and exacerbations of unpredictable frequency and duration. The disease has a worldwide distribution, but the majority of cases cluster along the ancient Silk Road, which extends from eastern Asia to the Mediterranean basin. The etiopathogenesis of BD is still unknown, but familial aggregation and peculiar geographical distribution have been regarded as evidence supporting genetic influence on the pathogenesis of BD. In this article, we describe a patient with BD, who had four members of his family associated with BD.
Yilmaz
Sema
S
Division of Rheumatology, Selcuklu Faculty of Medicine, Selcuk University, Vatan cad. Devrim sitesi B/Blok No.: 25/4, 42040, Selcuklu, Konya, Turkey. drsemayilmaznew@gmail.com
Cimen
Kadriye Akar
KA
D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D015235:HLA-B Antigens / Q000235:genetics; D059949:HLA-B51 Antigen; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome
D015235:HLA-B Antigens; D059949:HLA-B51 Antigen