Bronchomalacia occurring in monozygotic twins--further information about its inheritance.
We report left main-stem bronchomalacia occurring in monozygotic twins that became symptomatic during infancy. This phenomenon has not previously been reported to occur in twins. Little is known about the aetiology of primary bronchomalacia, but this occurrence suggests that there may be a significant genetic component in some cases.


CONCLUSIONS
Left main-stem bronchomalacia occurring in monozygotic twins suggests that there may be a significant genetic component in some cases and provides further information about the inheritance of this condition.
Brodlie
Malcolm
M
Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK. m.j.brodlie@ncl.ac.uk
Spencer
David A
DA
D055091:Bronchomalacia / Q000175:diagnosis / Q000235:genetics*; D001999:Bronchoscopy / Q000379:methods; D004200:Diseases in Twins / Q000235:genetics*; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D012135:Respiratory Sounds / Q000209:etiology; D012141:Respiratory Tract Infections / Q000628:therapy; D014430:Twins, Monozygotic