title: How subchronic and chronic health effects can be neglected for GMOs, pesticides or chemicals.
abstract: Chronic health effects are increasing in the world such as cancers, hormonal, reproductive, nervous, or immune diseases, even in young people. During regulatory toxicological subchronic tests to prevent these on mammalian health, prior commercialization of chemicals, including pesticides and drugs, or GMOs, some statistically significant findings may be revealed. This discussion is about the need to investigate the relevant criteria to consider those as biologically significant. The sex differences and the non linear dose or time related effects should be considered in contrast to the claims of a Monsanto-supported expert panel about a GMO, the MON 863 Bt maize, but also for pesticides or drugs, in particular to reveal hormone-dependent diseases and first signs of toxicities.
authors: University of Caen, Institute of Biology, Biochemistry, Esplanade de la Paix, 14032 Caen Cedex, France. criigen@unicaen.fr
authors: Gilles-Eric
authors: GE
authors: Séralini
authors: Joël Spiroux
authors: JS
authors: de Vendômois
authors: Dominique
authors: D
authors: Cellier
authors: Charles
authors: C
authors: Sultan
authors: Marcello
authors: M
authors: Buiatti
authors: Lou
authors: L
authors: Gallagher
authors: Michael
authors: M
authors: Antoniou
authors: Krishna R
authors: KR
authors: Dronamraju
mesh_terms: D000818:Animals; D015386:Hazardous Substances / Q000633:toxicity*; D006801:Humans; D030781:Organisms, Genetically Modified; D010575:Pesticides / Q000633:toxicity*; D012727:Sex Characteristics; D036401:Toxicity Tests, Chronic
chemical_list: D015386:Hazardous Substances; D010575:Pesticides