Amino acid synthesis in a supercritical carbon dioxide - water system.
Mars is a CO(2)-abundant planet, whereas early Earth is thought to be also CO(2)-abundant. In addition, water was also discovered on Mars in 2008. From the facts and theory, we assumed that soda fountains were present on both planets, and this affected amino acid synthesis. Here, using a supercritical CO(2)/liquid H(2)O (10:1) system which mimicked crust soda fountains, we demonstrate production of amino acids from hydroxylamine (nitrogen source) and keto acids (oxylic acid sources). In this research, several amino acids were detected with an amino acid analyzer. Moreover, alanine polymers were detected with LC-MS. Our research lights up a new pathway in the study of life's origin.
Fujioka
Kouki
K
International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.|Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan.
Futamura
Yasuhiro
Y
International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
Shiohara
Tomoo
T
Sekisui Chemical Co., Ltd., 2-1 Hyakuyama, Shimamoto-cho, Mishima-gun, Osaka, Japan.
Hoshino
Akiyoshi
A
International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
Kanaya
Fumihide
F
International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
Manome
Yoshinobu
Y
Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan.
Yamamoto
Kenji
K
International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D019811:Hydroxylamine / Q000737:chemistry; D007651:Keto Acids / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D013696:Temperature; D014867:Water / Q000737:chemistry*
D000596:Amino Acids; D007651:Keto Acids; D010455:Peptides; D014867:Water; D002245:Carbon Dioxide; C019529:polyalanine; D019811:Hydroxylamine