title: Sol-gel synthesis of macro-mesoporous titania monoliths and their applications to chromatographic separation media for organophosphate compounds.
abstract: We have developed a method of independently tailoring the macro- and mesoporous structures in titania (TiO2) monoliths in order to achieve liquid chromatographic separations of phosphorous-containing compounds. Anatase TiO2 monolithic gels with well-defined bicontinuous macropores and microstructured skeletons are obtained via the sol-gel process in strongly acidic conditions using poly(ethylene oxide) as a phase separator and N-methylformamide as a proton scavenger. Aging treatment of the wet gels in the mother liquor at temperatures of 100-200 degrees C and subsequent heat treatment at 400 degrees C allow the formation and control of mesoporous structures with uniform pore size distributions in the gel skeletons, without disturbing the preformed macroporous morphology. The monolithic TiO2 rod columns with bimodal macro-mesoporous structures possess the phospho-sensitivity and exhibit excellent chromatographic separations of phosphorus-containing compounds.
authors: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.
authors: Junko
authors: J
authors: Konishi
authors: Koji
authors: K
authors: Fujita
authors: Kazuki
authors: K
authors: Nakanishi
authors: Kazuyuki
authors: K
authors: Hirao
authors: Kei
authors: K
authors: Morisato
authors: Shota
authors: S
authors: Miyazaki
authors: Masayoshi
authors: M
authors: Ohira
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D009943:Organophosphorus Compounds / Q000737:chemistry; D016062:Porosity; D013696:Temperature; D014025:Titanium / Q000737:chemistry*
chemical_list: D009943:Organophosphorus Compounds; C009495:titanium dioxide; D014025:Titanium