A QSAR-like analysis of the adsorption of endocrine disrupting compounds, pharmaceuticals, and personal care products on modified activated carbons.
Rapid small-scale column tests (RSSCTs) examined the removal of 29 endocrine disrupting compounds (EDCs) and pharmaceutical/personal care products (PPCPs). The RSSCTs employed three lignite variants: HYDRODARCO 4000 (HD4000), steam-modified HD4000, and methane/steam-modified HD4000. RSSCTs used native Lake Mead, NV water spiked with 100-200 ppt each of 29 EDCs/PPCPs. For the steam and methane/steam variants, breakthrough occurred at 14,000-92,000 bed volumes (BV); and this was 3-4 times more bed volumes than for HD4000. Most EDC/PPCP bed life data were describable by a normalized quantitative structure-activity relationship (i.e. QSAR-like model) of the form: where TPV is the pore volume, rho(mc) is the apparent density, CV is the molecular volume, C(o) is the concentration, (8)chi(p) depicts the molecule's compactness, and FOSA is the molecule's hydrophobic surface area.
Redding
Adam M
AM
Department of Civil and Environmental Engineering, The Pennsylvania State University, University Park, PA 16802, USA. adam.redding@gmail.com
Cannon
Fred S
FS
Snyder
Shane A
SA
Vanderford
Brett J
BJ
D000327:Adsorption / Q000187:drug effects; D002606:Charcoal / Q000737:chemistry; D052244:Endocrine Disruptors / Q000032:analysis* / Q000737:chemistry; D006795:Household Products / Q000032:analysis*; D008956:Models, Chemical; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000737:chemistry; D021281:Quantitative Structure-Activity Relationship; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry; D018508:Water Purification / Q000379:methods
D052244:Endocrine Disruptors; D004364:Pharmaceutical Preparations; D014874:Water Pollutants, Chemical; D002606:Charcoal