title: Primary dedifferentiated chondrosarcoma of the lung.
abstract: Extraskeletal dedifferentiated chondrosarcomas (DC) are uncommon tumors that predominantly occur in the head and neck. Herein, we describe a case of pulmonary DC detected in a patient with systemic sclerosis and presenting with a symptomatic large pleural effusion and a pulmonary lobar consolidation on chest imaging. To the best of our knowledge, this is the first report of pulmonary chondrosarcoma involving the pleura and occurring in association with systemic sclerosis. Moreover, this is the second report of a dedifferentiated variant among all reported cases of primary lung chondrosarcoma.
authors: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. aelboue1@jhmi.edu
authors: Adel
authors: A
authors: Boueiz
authors: Marwan S
authors: MS
authors: Abougergi
authors: Carlos
authors: C
authors: Noujeim
authors: Alexis
authors: A
authors: Bousamra
authors: Pierre
authors: P
authors: Sfeir
authors: Ghazi
authors: G
authors: Zaatari
authors: Pierre
authors: P
authors: Bou-Khalil
mesh_terms: D002813:Chondrosarcoma / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008875:Middle Aged; D010994:Pleura / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D012595:Scleroderma, Systemic / Q000150:complications