Conditioned taste aversion induced by diethyldithiocarbamate (DDC).
Subcutaneous injections of 150, 300, or 600 mg/kg diethyldithiocarbamate (DDC) immediately following a 0.5 h exposure to a novel saccharin solution caused a pronounced aversion to saccharin in rats when tested four days later. No statistical difference was observed between the effects of these dosages. These results suggest that DDC possesses punishing properties and that the previously reported amnesic properties of DDC are not apparent in all passive avoidance tasks.
Roberts
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DC
Division of Neurological Sciences, Department of Psychiatry, University of British Columbia, Vancouver, B.C. V6T 1W5 Canada.
Fibiger
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HC