title: [Efficacy of lamysil dermgel in treatment of tinea versicolor].
abstract: The fungi of the genus Malassezia are part of normal mycobiota of human and mammal skin. As a representative of the normal mycobiota skin warm-blooded animals and humans, under certain conditions they can cause pathological process including tinea versicolor - a common skin infection. In spite of existence of broad-spectrum antibiotics and antifungals for the treatment of skin diseases the efficacy of drugs aren't always successful. The aim of the study was to estimate efficacy of lamysil dermgel in comparison with clotrimazole in the treatment of tinea versicolor. The study population included 43 patients of both sex. The diagnosis of tinea versicolor was confirmed by assessment of signs and symptoms, test-positive by Balzer and by microscopy, which revealed the presence of fungus of the Malassezia genus. By the post treatment examination treatment success had been achieved in both groups, but significantly higher percentages was achieved in lamysil dermgel group. Treatment success rate in lamysil dermgel group: clinical cure - 21 patients (95,45%), mycologic cure - 19 patients (86,3%), full - 18 patients (81,81%). In clotrimazole group: clinicaly cure - 17 patients (80,95%), mycologic cure - 13 patients (61,9%), full - 13 patients (61,9%).The results of our study confirm highly antifungal activity of lamysil dermgel against tinea versicolor and suggest that it may be more effective then clotrimazole, therefore it will be approved for treatment of this dermatosis.
authors: L R
authors: LR
authors: Beridze
authors: T G
authors: TG
authors: Katsitadze
mesh_terms: D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D000077291:Terbinafine; D014010:Tinea Versicolor / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine