Depression, sexually transmitted infection, and sexual risk behavior among young adults in the United States.
OBJECTIVE
To measure associations among depression, sexual risk behaviors, and sexually transmitted infection (STI) among white and black youth in the United States.


METHODS
Analysis of prospective cohort study data. Wave I of the National Longitudinal Study of Adolescent Health occurred in 1995 when participants were in grades 7 through 12. Six years later, all Wave I participants who could be located were invited to participate in Wave III and to provide a urine specimen for STI testing.


METHODS
In-home interviews in the continental United States, Alaska, and Hawaii.


METHODS
Population-based sample. A total of 10 783 Wave I (adolescence) and Wave III (adulthood) white and black respondents with sample weight variables. Main Exposures Chronic depression (detected at Waves I and III) and recent depression (detected at Wave III only) vs no adult depression (not detected at Wave III).


METHODS
Multiple sexual partners and inconsistent condom use in the past year and a current positive test result for Chlamydia trachomatis, Neisseria gonorrhoeae, or Trichomonas vaginalis (adulthood).


RESULTS
Recent or chronic depression in adulthood was more common for blacks (women, 19.3%; men, 11.9%) than for whites (women, 13.0%; men, 8.1%). Among all groups (white men and women, and black men and women), adult depression was associated with multiple partners but not with condom use. Among black men, depression was strongly associated with STI (recent: adjusted prevalence ratio, 2.36; 95% confidence interval, 1.26-4.43; chronic: adjusted prevalence ratio, 3.05; 95% confidence interval, 1.48-6.28); having multiple partners did not mediate associations between depression and STI.


CONCLUSIONS
Integration of mental health and STI programs for youth is warranted. Further research is needed to elucidate how depression may influence the prevalence of STI among black men.
Khan
Maria R
MR
Department of Epidemiology,School of Public Health, The University of North Carolina at Chapel Hill, NC, USA. maria_khan@unc.edu
Kaufman
Jay S
JS
Pence
Brian Wells
BW
Gaynes
Bradley N
BN
Adimora
Adaora A
AA
Weir
Sharon S
SS
Miller
William C
WC
D000293:Adolescent; D000294:Adolescent Behavior; D001741:Black or African American / Q000706:statistics & numerical data; D002908:Chronic Disease; D015986:Confounding Factors, Epidemiologic; D003863:Depression / Q000453:epidemiology* / Q000208:ethnology; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D000297:Psychology, Adolescent; D012307:Risk Factors; D012309:Risk-Taking; D012737:Sex Factors; D012725:Sexual Behavior; D012747:Sexual Partners; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000208:ethnology; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000208:ethnology; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data; D055815:Young Adult