Pancreas allograft thrombosis following intravenous immunoglobulin administration to treat parvovirus B19 infection.
Pancreas graft thrombosis is one of the commonest non-immunological causes for early graft loss after transplantation. This case report describes a patient who developed graft thrombosis after intravenous immunoglobulin administration to treat acute parvovirus B19 infection. The potential role of hypercoagulability in graft thrombosis and the implications for immunoglobulin therapy in transplant patients with hypercoagulable states is discussed.
Muthusamy
A S R
AS
Oxford Transplant Centre, Churchill Hospital, Oxford, UK.
Vaidya
A C
AC
Sinha
S
S
Atabani
S F
SF
Haque
T
T
Jones
G
G
Cunningham
J
J
Friend
P J
PJ
D000328:Adult; D001777:Blood Coagulation / Q000502:physiology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects / Q000627:therapeutic use; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use; D016035:Pancreas Transplantation / Q000009:adverse effects*; D010322:Parvoviridae Infections / Q000276:immunology / Q000628:therapy*; D016732:Parvovirus B19, Human / Q000276:immunology*; D013927:Thrombosis / Q000209:etiology*; D014184:Transplantation, Homologous / Q000009:adverse effects*
D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors