title: A comparison of perioperative morbidity, perioperative mortality, and disease-specific survival in elderly women (>or=70 years) versus younger women (<70 years) with endometrioid endometrial cancer.
abstract: OBJECTIVE
  The study compares the perioperative morbidity and mortality rates of elderly (>or=70 years) and younger (<70 years) patients with endometrioid endometrial cancer.
  
  
  METHODS
  The study cohort consisted of 115 consecutive women undergoing explorative laparotomy because of endometrioid endometrial cancer. Clinical data included patients' age, comorbidities, chronic use of medications, body mass index (kg/m), previous surgical procedures, surgical International Federation of Gynecology and Obstetrics stage, histological grade, relevant prognostic factors, a number of dissected lymph nodes, occurrence of perioperative complications, postoperative hospital stay (in days), and long-term disease-specific survival (in months).
  
  
  RESULTS
  Patients were divided into 2 groups: those younger than 70 years (group 1: 84 women, 73%) and those 70 years or older (group 2: 31 women, 27%). Although, as expected, elderly women had more major comorbidities, the rate of perioperative complications was similar between the 2 groups. In a logistic regression model, only chronic lung disease, gastrointestinal disease, and past abdominal surgery correlated with a higher rate of perioperative complications. None of the cohort patients died during the perioperative period. The long-term disease-specific survival was significantly poorer for the older group.
  
  
  CONCLUSIONS
  Chronological age by itself should not be a contraindication for the proper surgical treatment of elderly women with endometrioid endometrial cancer, because it is a poor predicting factor for perioperative morbidity and mortality.
authors: Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel.
authors: Zvi
authors: Z
authors: Vaknin
authors: Ido
authors: I
authors: Ben-Ami
authors: David
authors: D
authors: Schneider
authors: Moty
authors: M
authors: Pansky
authors: Reuvit
authors: R
authors: Halperin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018269:Carcinoma, Endometrioid / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D015331:Cohort Studies; D016889:Endometrial Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D009367:Neoplasm Staging; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome