Epinephrine localization in human brain stem.
A study was undertaken to determine the presence and possible localization of epinephrine (E) in the human brain stem. Three brain stems were analyzed, although detailed mapping was performed only on the third. E was found to be highly localized in the reticular formation and the aqueductal gray. The highest concentrations were found in the region of the floor of the fourth ventricle. Norepinephrine (NE) and dopamine (DA) determinations were included in the analyses. These catecholamines were also found to be localized in the same regions. The relative E concentrations ranged from about 1-10% of the total catecholamine content.
Mefford
I
I
Department of Chemistry, University of Kansas, Lawrence, Kans. 66045 U.S.A.
Oke
A
A
Adams
R N
RN
Jonsson
G
G