title: Daily measurement of organic compounds in ambient particulate matter in Augsburg, Germany: new aspects on aerosol sources and aerosol related health effects.
abstract: Several epidemiological studies have shown that in the human population ambient particulate matter (PM) is associated with adverse health effects. Little is known, however, about the relative effects of aerosol constituents. Since 2002, diurnal samples of ambient PM2.5 were analysed by automated methods for the quantification of particle-associated organic compounds (POC). Data on chemical composition have been investigated in epidemiological and biological effect studies. As a result of these studies, the associations found between PAH concentration and symptoms of myocardial infarction survivors suggest a major influence of combustion sources on cardiovascular health effects. The correlations found between formation of reactive oxygen species and the presence of specific organic compounds suggests an important influence of biomass combustion particles in PM2.5-associated oxidative stress.
authors: Helmholtz Zentrum München, National Research Center for Environmental Health, Neuherberg, Germany. juergen.schnelle@helmholtz-muenchen.de
authors: Jürgen
authors: J
authors: Schnelle-Kreis
authors: Ute
authors: U
authors: Küpper
authors: Martin
authors: M
authors: Sklorz
authors: Josef
authors: J
authors: Cyrys
authors: Jacob Jan
authors: JJ
authors: Briedé
authors: Annette
authors: A
authors: Peters
authors: Ralf
authors: R
authors: Zimmermann
mesh_terms: D000336:Aerosols; D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis*; D002319:Cardiovascular System / Q000187:drug effects / Q000378:metabolism; D004782:Environmental Health; D004784:Environmental Monitoring / Q000379:methods; D005858:Germany; D006801:Humans; D009203:Myocardial Infarction / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects; D010316:Particle Size; D052638:Particulate Matter / Q000009:adverse effects / Q000032:analysis*; D011084:Polycyclic Aromatic Hydrocarbons / Q000009:adverse effects / Q000032:analysis*; D017382:Reactive Oxygen Species / Q000378:metabolism; D018570:Risk Assessment; D013997:Time Factors
chemical_list: D000336:Aerosols; D000393:Air Pollutants; D052638:Particulate Matter; D011084:Polycyclic Aromatic Hydrocarbons; D017382:Reactive Oxygen Species