[Application of atomic force microscopy in chromosome research].
Atomic force microscopy (AFM) is an effective apparatus for examination of the surface structure of specimens with a higher resolution. It can be used for real-time observation in vacuum, air, and liquid conditions. This review presented the basic principle of AFM and its significant advantages in biological sample research relative to other types of microscopes and summarized its application in chromosome research.
Li
Qi
Q
Faculty of Life Sciences, Northwestern Polytechnic University, Xi'an 710072, China. caddie1111@yahoo.com.cn
Zheng
Qi
Q
Ding
Yan
Y
Ma
Lu
L
Li
Li-Jia
LJ
D000818:Animals; D002875:Chromosomes / Q000737:chemistry* / Q000648:ultrastructure; D005544:Forecasting; D006801:Humans; D018625:Microscopy, Atomic Force / Q000295:instrumentation* / Q000379:methods*; D046529:Microscopy, Electron, Transmission; D012106:Research