title: Pediatric littoral cell angioma of the spleen: multimodality imaging including diffusion-weighted imaging.
abstract: Littoral cell angioma (LCA) is a rare primary splenic vascular tumor originating from littoral cells lining the splenic red pulp sinuses. LCAs are rarely seen in children. We present the US, CT, and MRI findings including diffusion-weighted imaging (DWI) in a 2-year-old boy with histologically proven LCA. Previous studies on liver lesions have shown that DWI allows differentiation of vascular tumors from primary neoplasms and metastatic disease. The current case indicates that increased ADC values within the splenic lesions suggest a vascular etiology, which might help narrow the differential diagnosis.
authors: Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD 21287-0842, USA.
authors: Gulhan
authors: G
authors: Ertan
authors: Aylin
authors: A
authors: Tekes
authors: Sally
authors: S
authors: Mitchell
authors: Jeffrey
authors: J
authors: Keefer
authors: Thierry A G M
authors: TA
authors: Huisman
mesh_terms: D002675:Child, Preschool; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006391:Hemangioma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D013160:Splenic Neoplasms / Q000175:diagnosis*; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*