title: [Research progress of hypoxia inducible factor 1alpha in hypoxic-ischemic injury].
abstract: OBJECTIVE
  To review the role of hypoxia inducible factor 1alpha (HIF-1alpha) in hypoxic-ischemic injury and its repair, and to analyze the possible mechanisms.
  
  
  METHODS
  Recent literature on HIF-1alpha and its role in hypoxic-ischemic injury was reviewed and analyzed.
  
  
  RESULTS
  HIF-1alpha was involved in the hypoxic-ischemic injury of various organs or tissues and their repair processes.
  
  
  CONCLUSIONS
  HIF-1alpha has a potential to treat common clinical hypoxic-ischemic injuries and has a promising future for application.
authors: Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu Sichuan, 610041, PR China.
authors: Binzhi
authors: B
authors: Tang
authors: Yi
authors: Y
authors: Qu
authors: Dezhi
authors: D
authors: Mu
mesh_terms: D006801:Humans; D000860:Hypoxia; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D007511:Ischemia
chemical_list: D051795:Hypoxia-Inducible Factor 1, alpha Subunit