Brugada and short QT syndromes.
Brugada syndrome and short QT syndrome are among the rarer cardiac channelopathies that may result in sudden cardiac arrest. The genetics and molecular mechanisms of these diseases provide insight into the mechanisms of more common channelopathies, and may dictate special therapeutic approaches with respect to drug therapy and risk stratification.
Triedman
John K
JK
Children's Hospital, Boston, Massachusetts, USA. john.triedman@cardio.chboston.org
D000293:Adolescent; D053840:Brugada Syndrome / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008955:Models, Cardiovascular; D055815:Young Adult