title: Surface plasmon-coupled directional emission based on a conformational-switching signaling aptamer.
abstract: We have observed highly polarized and directional surface plasmon-coupled emission of a signaling aptamer due to the binding of a target thrombin with the aptamer, which induces conformational switching.
authors: Department of Chemistry, College of Chemistry and Chemical Engineering, The Key Laboratory of Analytical Sciences of the Ministry of Education, Xiamen University, Xiamen, Fujian 361005, China.
authors: Tang-Tang
authors: TT
authors: Xie
authors: Qian
authors: Q
authors: Liu
authors: Wei-Peng
authors: WP
authors: Cai
authors: Zhe
authors: Z
authors: Chen
authors: Yao-Qun
authors: YQ
authors: Li
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D006046:Gold / Q000737:chemistry; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D013050:Spectrometry, Fluorescence; D020349:Surface Plasmon Resonance; D013499:Surface Properties; D013917:Thrombin / Q000378:metabolism / Q000494:pharmacology
chemical_list: D052157:Aptamers, Nucleotide; D006046:Gold; D013917:Thrombin