The nucleus accumbens of rats and dopaminergic mechanisms regulating locomotor behaviour.
Dopamine and (3,4-dihydroxyphenylamino)-2-imidazoline (DPI) were injected into the nucleus accumbens of rats locally pretreated with ergometrine. The results show that the ergometrine-induced locomotor activity is inhibited by both compounds suggesting that ergometrine inhibits certain types of dopamine receptors. The data are discussed in terms of distinct types of dopamine receptors.
Cools
A R
AR
Department of Pharmacology, University of Nijmegen, Nijmegen The Netherlands.
Honig
W M
WM
Pijnenburg
A J
AJ
Van Rossum
J M
JM