title: Noninnocent behavior of ancillary ligands: apparent trans coupling of a saturated N-heterocyclic carbene unit with an ethyl ligand mediated by nickel.
abstract: Oxidative addition of the tridentate N-heterocyclic carbene (NHC) diphosphine ligand precursor ([PCP]H)PF(6) (1) {[PCP] = o-(i)Pr(2)PC(6)H(4)(NC(3)H(4)N)o-C(6)H(4)P(i)Pr(2)} to Ni(COD)(2) results in the formation of the nickel(II) hydride complex ([PCP]NiH)PF(6) (2). This hydride undergoes a rapid reaction with ethylene to generate a nickel(0) complex in which an ethyl group has been transferred to the carbene carbon of the original NHC-diphosphine ligand. If the first intermediate is the anticipated square-planar nickel(II) ethyl species, then the formation of the product would require a process that involves a trans C-C coupling of the NHC carbon and a presumed Ni-ethyl intermediate. Deuterium-labeling studies provide evidence for migratory insertion of the added ethylene into the Ni-H bond rather than into the Ni-carbene linkage; this is based on the observed deuterium scrambling, which requires reversible beta-elimination, alkene rotation, and hydride readdition. However, density functional theory studies suggest that a key intermediate is an agostic ethyl species that has the Ni-C bond cis to the NHC unit. A possible transition state containing two cis-disposed carbon moieties was also identified. Such a process represents a new pathway for catalyst deactivation involving NHC-based metal complexes.
authors: Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z4.
authors: Tobias
authors: T
authors: Steinke
authors: Bryan K
authors: BK
authors: Shaw
authors: Howard
authors: H
authors: Jong
authors: Brian O
authors: BO
authors: Patrick
authors: Michael D
authors: MD
authors: Fryzuk
authors: Jennifer C
authors: JC
authors: Green