Hydrogen-bonded multilayer of pH-responsive polymeric micelles with tannic acid for surface drug delivery.
We report the design of a platform for the delivery of hydrophobic drugs conjugated to block copolymer micelles via pH-responsive linkage that are assembled within hydrogen-bonded polymer multilayer thin films.
Kim
Byeong-Su
BS
Department of Chemical Engineering and Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA 02138, USA.
Lee
Hyung-Il
HI
Min
Yunhong
Y
Poon
Zhiyong
Z
Hammond
Paula T
PT
D004337:Drug Carriers; D006367:HeLa Cells; D006801:Humans; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D008823:Micelles; D018625:Microscopy, Atomic Force; D011108:Polymers / Q000737:chemistry*; D013634:Tannins / Q000737:chemistry*
D004337:Drug Carriers; D008823:Micelles; D011108:Polymers; D013634:Tannins