M-protein-positive chronic active Epstein-Barr virus infection: features mimicking HIV-1 infection.
Chronic active Epstein-Barr virus infection (CAEBV) is a unique and fatal lymphoproliferative disease (LPD), which often shows high serum IgG and/or IgE. The significance of such immunoglobulin abnormalities in CAEBV has not been fully evaluated and discussed. In addition, such clinical features mimic HIV-1 infection. We report here a case of CAEBV with M-protein detected which may shed a new light on the pathogenesis of this disease.
Imashuku
Shinsaku
S
Division of Pediatrics and Hematology, Takasago-seibu Hospital, 1-10-41, Nakasuji Takasago, Hyogo, 676-0812, Japan. shinim95@mbox.kyoto-inet.or.jp.
Azuma
Naoto
N
Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Kanegane
Hirokazu
H
Department of Pediatrics, Graduate School of Medicine, University of Toyama, Toyama, Japan.
Kasahara
Yoshihito
Y
Department of Pediatrics, School of Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
D000328:Adult; D044466:Asian People; D002908:Chronic Disease; D003937:Diagnosis, Differential; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis* / Q000276:immunology; D015658:HIV Infections / Q000175:diagnosis* / Q000276:immunology; D015497:HIV-1; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis* / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology*; D008297:Male
D007075:Immunoglobulin M