Estimating HIV-1 incidence using the serologic testing algorithm for recent HIV infections at HIV counseling and testing centers in the city of São Paulo, Brazil.
The network of HIV counseling and testing centers in São Paulo, Brazil is a major source of data used to build epidemiological profiles of the client population. We examined HIV-1 incidence from November 2000 to April 2001, comparing epidemiological and socio-behavioral data of recently-infected individuals with those with long-standing infection. A less sensitive ELISA was employed to identify recent infection. The overall incidence of HIV-1 infection was 0.53/100/year (95% CI: 0.31-0.85/100/year): 0.77/100/year for males (95% CI: 0.42-1.27/100/year) and 0.22/100/ year (95% CI: 0.05-0.59/100/year) for females. Overall HIV-1 prevalence was 3.2% (95% CI: 2.8-3.7%), being 4.0% among males (95% CI: 3.3-4.7%) and 2.1% among females (95% CI: 1.6-2.8%). Recent infections accounted for 15% of the total (95% CI: 10.2-20.8%). Recent infection correlated with being younger and male (p = 0.019). Therefore, recent infection was more common among younger males and older females.
Bassichetto
Katia Cristina
KC
Coordenação Municipal de DST/AIDS - Secretaria Municipal de Saúde de São Paulo, Brazil.
Bergamaschi
Denise Pimentel
DP
Veras
Maria Amelia
MA
Sucupira
Maria Cecilia Araripe
MC
Mesquita
Fabio
F
Diaz
Ricardo Sobhie
RS
D000328:Adult; D000465:Algorithms; D001938:Brazil / Q000453:epidemiology; D003376:Counseling; D004797:Enzyme-Linked Immunosorbent Assay; D016021:Epidemiologic Studies; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012959:Socioeconomic Factors; D055815:Young Adult