Hepatopulmonary syndrome and liver sarcoidosis: a tale of two diseases.
Hepatopulmonary syndrome (HSP) is characterized by the triad of advanced liver disease, arterial hypoxemia, and intrapulmonary vascular dilatation. Most cases of HSP are associated with cirrhotic portal hypertension; however, it has also been reported in acute liver failure patients. An estimated prevalence of HPS in patients with chronic liver disease is around 5-32%. Sarcoidosis is a granulomatous disorder with noncaseating granulomas involving the lungs in 90% of cases. Sarcoidosis can involve the liver but in only about 1% of cases does it lead to cirrhosis and portal hypertension. In this review, we report a rare case of liver cirrhosis due to sarcoidosis with associated hepatopulmonary syndrome and discuss this in detail.
Patel
Anil N
AN
SUNY at Buffalo, Hospitalist, Faxton-St. Luke's Hospital, Utica, NY 13502, USA. dranpatel@gmail.com
Patel
Khyati
K
Mador
M Jeffrey
MJ
D005260:Female; D020065:Hepatopulmonary Syndrome / Q000150:complications*; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008103:Liver Cirrhosis / Q000209:etiology; D008107:Liver Diseases / Q000150:complications* / Q000473:pathology*; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology*