Coexistence of cerebral aneurysm and meningioma--pure accident?
OBJECTIVE
Coexisting intracerebral aneurysms and meningiomas occur relatively rarely, without a clear relationship, although an aneurysm can be located within a meningioma. The aim of this retrospective study was to identify possible explanations for the coexistence of these conditions and to present a rationale for treatment strategies.


METHODS
Ninety-five patients with coexistent meningioma and aneurysm were found in the National Library of Medicine, and 11 more patients were retrieved from our own database.


RESULTS
Co-occurrence of both pathologies, sometimes solitary, sometimes multiple, was mostly found in women (3:1). Clinical symptoms in the majority of patients were caused by tumour growth, whereas aneurysm rupture was seen only in a few cases. Consequently tumour resection was performed first in 58 out of the 95 patients, and aneurysm treatment in 38 patients. From available data, the mortality rate three decades before was approximately 40%, but decreased in the last years, due to microsurgical and endovascular techniques. All of our patients were alive after 1 year of follow-up. In patients with intratumoural aneurysms, only three published and one our own case, were treated for both pathologies.


CONCLUSIONS
The coexistence of meningioma and aneurysm seems to be a coincidence. Treatment should primary focus on the cause of presenting symptoms, but in cases with intratumoural aneurysm, the aneurysm should be treated first. Due to the development of microsurgical and endovascular techniques peri-procedural mortality and morbidity has decreased.
Fischer
B R
BR
Department of Neurosurgery, University Hospital of Muenster, Albert-Schweitzer-Strasse 33, 48129 Muenster, Germany. fischeb@mednet.uni-muenster.de
Palkovic
S
S
Holling
M
M
Niederstadt
T
T
Jeibmann
A
A
Wassmann
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D002648:Child; D015331:Cohort Studies; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008297:Male; D008579:Meningioma / Q000150:complications* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008866:Microsurgery / Q000639:trends; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000639:trends; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult