title: Spectroscopic and antimicrobial studies of La3+, Pr3+, Nd3+ and Gd3+ complexes of a dipodal [N,N,N] chelating ligand.
abstract: The lanthanide complexes of bis(benzimidazole-2'-yl-methyl)amine (BImz) having molecular formula [M(BImz)X(3)H(2)O]*nH(2)O (M = La, Pr, Nd, or Gd; X = Cl or ClO(4) and n = 1, 2 or 3) were prepared and characterized spectroscopically through IR, (1)H and (13)C NMR, FAB-mass, UV-visible and luminescence spectroscopy. TGA data suggested presence of coordinated and the lattice water. The oscillator strengths of the f-f transitions and the covalency parameters (beta, b(1/2) and delta) have been evaluated from the electronic spectral data. The proposed hepta-coordinate geometry for the complexes has been ascertained from the molecular model computations. CV studies indicate formation of a stable quasi-reversible redox couple Gd(III/IV) in the solution. The in vivo antimicrobial activities of the complexes have been evaluated against gram +ve and gram -ve bacteria and fungi.
authors: Coordination Chemistry Research Group, Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India. zafarasiddiqi@yahoo.co.in
authors: Zafar A
authors: ZA
authors: Siddiqi
authors: M
authors: M
authors: Shahid
authors: Mohd
authors: M
authors: Khalid
authors: Shabana
authors: S
authors: Noor
authors: S
authors: S
authors: Kumar
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001562:Benzimidazoles / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D002614:Chelating Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D028581:Lanthanoid Series Elements / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D008024:Ligands; D008744:Methylamines / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D013057:Spectrum Analysis
chemical_list: D000890:Anti-Infective Agents; D001562:Benzimidazoles; D002614:Chelating Agents; D028581:Lanthanoid Series Elements; D008024:Ligands; D008744:Methylamines; C027451:methylamine; C031000:benzimidazole