Cytotoxic triterpenoids from the rhizomes of Astilbe chinensis.
Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.
Cai
Xing-Fu
XF
Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea.
Park
Bo-Young
BY
Ahn
Kyung-Seop
KS
Kwon
Ok-Kyoung
OK
Lee
Hyeong-Kyu
HK
Oh
Sei-Ryang
SR
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007723:Korea; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D031995:Saxifragaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes