title: A DNA-binding Gd chelate for the detection of cell death by MRI.
abstract: GadoTO, a MR contrast agent for the detection of cell death, consists of a nucleic acid-binding fluorophore attached to a gadolinium chelate.
authors: Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
authors: Elisabeth
authors: E
authors: Garanger
authors: Scott A
authors: SA
authors: Hilderbrand
authors: Joseph T
authors: JT
authors: Blois
authors: David E
authors: DE
authors: Sosnovik
authors: Ralph
authors: R
authors: Weissleder
authors: Lee
authors: L
authors: Josephson
mesh_terms: D016923:Cell Death; D002614:Chelating Agents / Q000737:chemistry*; D003287:Contrast Media / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D005682:Gadolinium / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002614:Chelating Agents; D003287:Contrast Media; C544434:GadoTO4; D009942:Organometallic Compounds; D004247:DNA; D005682:Gadolinium