A volumetric study of the corpus callosum in 20s and 40s Korean people.
The purpose of this study was to measure the average corpus callosum volume of normal Koreans (aged in their 20s or 40s) and to analyze the effects of gender, age, and body parameters, such as height and weight on corpus callosum size. Magnetic resonance brain images were recorded for 68 people in their 20s (29 men, 39 women) and 91 in their 40s (36 men, 55 women). Intracranial volume was calculated using cerebral size and corpus callosum volume was normalized by covariance method. To investigate the effect of gender and age on corpus callosum volume, two-way analysis of variance, which used gender (two levels) and age (two levels) as independent variables, was employed. Multiple regression analysis was carried out to investigate the effect of body parameters, such as height and weight, according to the age and gender on the changes in corpus callosum volume. The average corpus callosum volume of Korean men (11.09 cm(3)) was larger than that of Korean women (9.61 cm(3)). There was no significant difference in corpus callosum volume between 20s (10.43 cm(3)) and 40s (10.12 cm(3)). There was a positive relationship between body weight and corpus callosum volume for 20s, but not for 40s.
Lee
Beob-Yi
BY
Department of Anatomy, School of Medicine, Konkuk University, Seoul, South Korea.
Sohn
Jin-Hun
JH
Choi
Mi-Hyun
MH
Lee
Su-Jeong
SJ
Kim
Hyo-Seong
HS
Yang
Jae-Woong
JW
Choi
Jin-Seung
JS
Kim
Hyung-Sik
HS
Yi
Jeong-Han
JH
Tack
Gye-Rae
GR
Chung
Soon-Cheol
SC
D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D044466:Asian People; D001835:Body Weight; D003337:Corpus Callosum / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007723:Korea; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D012044:Regression Analysis; D012737:Sex Factors; D012886:Skull / Q000033:anatomy & histology