[A case of cutaneous and mucous haemorrhage secondary to vitamin K deficiency in hyperemesis gravidarum].
The frequency of the syndrome of hyperemesis gravidarum (HG) varies from 0.1 to 2% according to the literature. The complications are generally benign. Some of them can compromise the life outcome. Only two cases of HG with bleeding disorder (major epitasis) related to a vitamin K deficiency were previous reported. Here is described a third case related to a vitamin deficiency K. It is characterized by a skin and mucosa haemorrhage (gingivorrhagias; bleeding in urine; bruises at the points of puncture) and by the necessity to treat her in emergency with fresh frozen plasma before intravenous vitamin K as soon as the diagnosis of vitamin K deficiency was done. The indication of the use of frozen fresh plasma is discussed.
Devignes
J
J
Service d'hématologie biologique,CHU de Nancy, avenue de Morvan, 54511 Vandoeuvre-Lès-Nancy, France.
Grare
M
M
Raft
J
J
Vial
F
F
Hacquard
M
M
Bouaziz
H
H
Lecompte
T
T
de Maistre
E
E
D001774:Blood Chemical Analysis; D001777:Blood Coagulation; D005260:Female; D006470:Hemorrhage / Q000097:blood / Q000209:etiology* / Q000628:therapy*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000628:therapy*; D009092:Mucous Membrane / Q000473:pathology; D010949:Plasma; D011247:Pregnancy; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome; D014812:Vitamin K / Q000627:therapeutic use; D014813:Vitamin K Deficiency / Q000097:blood / Q000150:complications*; D055815:Young Adult
D006490:Hemostatics; D014812:Vitamin K