title: Mantle cell lymphoma stage IV affecting lacrimal glands, retro-orbital tissue, optic nerve and ocular motor muscles.
abstract: Mantle cell lymphoma (MCL) is an entity which exceptionally affects the ocular region and periorbital tissues, but which should be included in the differential diagnosis of lesions which affect the orbital region in a diffused manner. We report the case of a 60-year-old patient diagnosed with stage IV MCL, whose fi rst clinical manifestation was a result of the damage of lacrimal glands, retro-orbital tissue and ocular motor muscles. The patient was treated with rituximab and chemotherapy, achieving a complete response of those lesions.
authors: Medical Oncology Department, Hospital Clínico Virgen de la Victoria, Campus Universitario Teatinos, Málaga, Spain. bellapajares@yahoo.es
authors: Bella
authors: B
authors: Pajares-Hachero
authors: Esperanza
authors: E
authors: Torres
authors: Isabel
authors: I
authors: Hierro
authors: José Miguel
authors: JM
authors: Jurado
authors: Antonio
authors: A
authors: Rueda
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents / Q000627:therapeutic use; D005123:Eye / Q000473:pathology; D005142:Eyelid Neoplasms / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology*; D020522:Lymphoma, Mantle-Cell / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009900:Optic Nerve / Q000473:pathology*; D009918:Orbital Neoplasms / Q000188:drug therapy / Q000473:pathology; D000069283:Rituximab
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D000069283:Rituximab