title: Psychiatric disorders: are they an absolute contraindication to living donation?
abstract: Little information has been published about the suitability of candidates for living organ donation who have a past or current psychiatric diagnosis. A retrospective review of 445 living donor kidney transplants performed at Barnes-Jewish Hospital's transplant center from 1995 to 2005 disclosed 42 donor candidates with such a history, prompting detailed psychological evaluation. Although 41 candidates (10% of the donor pool) met criteria for 1 or more psychiatric diagnoses, none were considered psychologically unfit for donation. Of these, 22 candidates underwent kidney donation without medical or surgical complications and without development of subsequent active psychological problems. Several donors maintained long-term contact up to 12 years to report good health and a high degree of satisfaction with the decision to donate. This experience suggests that for donor candidates with a psychiatric diagnosis, formal psychiatric evaluation to evaluate current mental health stability is warranted. Stable individuals, on or off therapy, can be considered fit to donate with expected short- and long-term outcome prognoses similar to those for the general population.
authors: Washington University School of Medicine, Department of Psychiatry, 660 S. Euclid, St Louis, MO 63110, USA.
authors: Anthony A
authors: AA
authors: Rowley
authors: Barry A
authors: BA
authors: Hong
authors: Susan
authors: S
authors: Martin
authors: Linda
authors: L
authors: Jones
authors: Anitha
authors: A
authors: Vijayan
authors: Surendra
authors: S
authors: Shenoy
authors: Martin
authors: M
authors: Jendrisak
mesh_terms: D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D046148:Donor Selection / Q000458:organization & administration*; D005260:Female; D016519:Hospitals, Religious; D006801:Humans; D007599:Judaism; D016030:Kidney Transplantation / Q000706:statistics & numerical data; D019520:Living Donors / Q000523:psychology / Q000706:statistics & numerical data; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D012017:Referral and Consultation / Q000458:organization & administration; D012189:Retrospective Studies; D009927:Tissue and Organ Procurement / Q000458:organization & administration*