Hydrophilic multi-walled carbon nanotubes decorated with magnetite nanoparticles as lymphatic targeted drug delivery vehicles.
Hydrophilic multi-walled carbon nanotubes decorated with magnetite nanoparticles were readily taken up into lymph vessels and delivered gemcitabine to lymph nodes with high efficiency under the guidance of a magnetic field.
Yang
Dong
D
Key Laboratory of Molecular Engineering of Polymers (Ministry of Education), Department of Macromolecular Science, Fudan University, Shanghai 200433, China.
Yang
Feng
F
Hu
Jianhua
J
Long
Jiang
J
Wang
Changchun
C
Fu
Deliang
D
Ni
Quanxing
Q
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000494:pharmacology; D016503:Drug Delivery Systems; D052203:Ferrosoferric Oxide / Q000737:chemistry; D008198:Lymph Nodes / Q000187:drug effects / Q000473:pathology; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D037742:Nanotubes, Carbon; D051381:Rats; D017207:Rats, Sprague-Dawley; D014867:Water / Q000737:chemistry*; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D037742:Nanotubes, Carbon; D014867:Water; D003841:Deoxycytidine; D052203:Ferrosoferric Oxide; D000093542:Gemcitabine