title: Design, synthesis, and bioactivity study of novel benzoylpyridazyl ureas.
abstract: A series of novel benzoylpyridazyl ureas were designed and synthesized from maleic anhydride and hydrazine monohydrate. These benzoylureas were identified by (1)H NMR spectroscopy and element analysis. The bioactivities of the new compounds were evaluated. These compounds exhibited larvicidal activities against oriental armyworm, and in particular, compound 13 displayed comparable activity to the commercial insecticide Hexaflumuron. Most of these compounds also had some larvicidal activities against mosquito. Interestingly, some compounds showed good plant growth regulatory activities.
authors: State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
authors: Ranfeng
authors: R
authors: Sun
authors: Yonglin
authors: Y
authors: Zhang
authors: Fuchun
authors: F
authors: Bi
authors: Qingmin
authors: Q
authors: Wang
mesh_terms: D000818:Animals; D001549:Benzamides; D003465:Culex; D015195:Drug Design; D006834:Hydrazines / Q000737:chemistry; D007306:Insecticides / Q000138:chemical synthesis* / Q000494:pharmacology; D007814:Larva; D007915:Lepidoptera; D008299:Maleic Anhydrides / Q000737:chemistry; D010671:Phenylurea Compounds; D063245:Plant Development; D010944:Plants / Q000187:drug effects; D011724:Pyridazines / Q000138:chemical synthesis*; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D005466:Fluorocarbons
chemical_list: D001549:Benzamides; D006834:Hydrazines; D007306:Insecticides; D008299:Maleic Anhydrides; D010671:Phenylurea Compounds; D011724:Pyridazines; D014508:Urea; C029424:hydrazine; C058039:hexafluoron; D005466:Fluorocarbons