Self-assembly and function of primitive cell membranes.
We describe possible pathways for separating amphiphilic molecules from organic material on the early earth to form membrane-bound structures required for the start of cellular life. We review properties of the first membranes and their function as permeability barriers. Finally, we discuss the emergence of protein-mediated ion transport across membranes, which facilitated many other cellular functions.
Pohorille
Andrew
A
Exobiology Branch, NASA Ames Research Center, MS 239-4, Moffett Field, CA 94035, USA. pohorill@max.arc.nasa.gov
Deamer
David
D
D005075:Biological Evolution; D002462:Cell Membrane / Q000378:metabolism*; D002463:Cell Membrane Permeability; D017136:Ion Transport; D008954:Models, Biological; D008958:Models, Molecular