[An analysis of clinical factors for coronary artery calcification score].
OBJECTIVE
To evaluate the correlating clinical factors of coronary artery calcification score (CACS).


METHODS
141 patients suspected of coronary artery disease were included. They underwent multi-slice row computed tomography, pulse wave velocity (PWV), UCG and blood biochemistry within a period of 3 months. The subjects were divided into three groups according to CAC score: A (CACS = 0 - 10), B (CACS = 11 - 400), C (CACS > 400).


RESULTS
CACS was significantly associated with age, history of hypertension and diabetes mellitus. It was also associated with the presence of mitral annular calcification and aortic valve calcification, low ankle brachial pressure index (ABI) and high mean artery pressure (MAP) as well as high values of brachial ankle PWV (baPWV) and Upstroke time (UT). Multifactorial logistic regression analysis showed that the presence of aortic valve calcification and mitral annular calcification, the history of diabetes mellitus and high value of UT were independently correlated with severe coronary artery calcification.


CONCLUSIONS
Aortic valve calcification, mitral annular calcification, history of diabetes mellitus, high value of UT were independently correlated with severe coronary artery calcification. Measurement of PWV and UCG should be performed before multi-slicerow computed tomography, because the assessment of coronary artery lumen narrowing with multi-slice row computed tomography can not be carried out accurately in the presence of severe coronary artery calcification.
Zhu
Hui-Nan
HN
Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
Huo
Yong
Y
Zhou
Jing
J
Wei
Hai-Liang
HL
Tong
Lin
L
Chu
Song-Yun
SY
Han
Xiao-Ning
XN
D000368:Aged; D002114:Calcinosis / Q000000981:diagnostic imaging*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D004452:Echocardiography / Q000706:statistics & numerical data; D005260:Female; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed