Paediatric germ cell tumours and congenital abnormalities: a Children's Oncology Group study.
METHODS
Maternally reported congenital abnormalities (CAs) were examined in a case-control study of 278 cases of paediatric germ cell tumours (GCTs) and 423 controls.


CONCLUSIONS
Germ cell tumours were significantly associated with cryptorchidism in males (OR=10.8, 95% CI: 2.1-55.1), but not with any other specific CA in either sex.
Johnson
K J
KJ
Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Ross
J A
JA
Poynter
J N
JN
Linabery
A M
AM
Robison
L L
LL
Shu
X O
XO
D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D000013:Congenital Abnormalities; D003456:Cryptorchidism / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000209:etiology*