title: Gender-linked differences in human skin.
abstract: BACKGROUND
  The physiology of body organs can be affected by gender. Skin and skin appendages are influenced by sex hormones.
  
  
  OBJECTIVE
  This review work has been undertaken to point out the most conspicuous physiological differences observed between men's and women's skin.
  
  
  METHODS
  The literature has been searched and relevant results have been gathered.
  
  
  RESULTS
  Men's and women's skins differ in hormone metabolism, hair growth, sweat rate, sebum production, surface pH, fat accumulation, serum leptins, etc. Examples of differences in the proneness to cutaneous diseases and skin cancer are quoted.
  
  
  CONCLUSIONS
  The knowledge of gender-linked cutaneous differences might help in preparing male-specific products for more appropriate dermatological treatments or cosmetic interventions.
authors: Clinique Laboratories, Melville, NY 11747, United States. pgiacomo@estee.com
authors: Paolo U
authors: PU
authors: Giacomoni
authors: Thomas
authors: T
authors: Mammone
authors: Matthew
authors: M
authors: Teri
mesh_terms: D003094:Collagen / Q000502:physiology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006197:Hair / Q000502:physiology; D006801:Humans; D008297:Male; D012627:Sebaceous Glands / Q000502:physiology*; D012727:Sex Characteristics; D012867:Skin; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology; D013545:Sweat Glands / Q000502:physiology*
chemical_list: D012739:Gonadal Steroid Hormones; D003094:Collagen