title: Color Doppler sonography and angioscintigraphy in hepatic Hodgkin's lymphoma.
abstract: OBJECTIVE
  To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma.
  
  
  METHODS
  The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index (HPI) estimated by HRA was calculated.
  
  
  RESULTS
  In the majority of patients, hepatomegaly was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins (P > 0.05). A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r = 390, P < 0.01). HPI was significantly lower in patients with lymphomas than in controls (P < 0.05), pointing out increased arterial perfusion in comparison to portal perfusion.
  
  
  CONCLUSIONS
  Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assessment of vascularisation of liver lesions.
authors: Institute for Digestive Diseases Clinical Center of Serbia, Visegradska 26, 11000 Belgrade, Serbia.
authors: Mirjana V
authors: MV
authors: Stojković
authors: Vera M
authors: VM
authors: Artiko
authors: Irena B
authors: IB
authors: Radoman
authors: Slavko J
authors: SJ
authors: Knezević
authors: Snezana M
authors: SM
authors: Lukić
authors: Mirko D
authors: MD
authors: Kerkez
authors: Nebojsa S
authors: NS
authors: Lekić
authors: Andrija A
authors: AA
authors: Antić
authors: Marinko M
authors: MM
authors: Zuvela
authors: Vitomir I
authors: VI
authors: Ranković
authors: Milorad N
authors: MN
authors: Petrović
authors: Dragana P
authors: DP
authors: Sobić
authors: Vladimir B
authors: VB
authors: Obradović
mesh_terms: D006689:Hodgkin Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging; D011875:Radionuclide Angiography; D018615:Ultrasonography, Doppler, Color