Distribution of pathogenic Yersinia enterocolitica in China.
Yersinia enterocolitica (1,295 strains) was isolated from diarrhea patients, livestock, poultry, wild animals, insect vectors, food, and the environment. They were studied for epidemiology distribution using bacterial biochemical metabolism tests, their virulence genes, and pulsed-field gel electrophoresis (PFGE) sub-typing. The data showed that 416 of the 1,295 strains were pathogenic, where the pathogenic Chinese isolates were of serotypes O:3 and O:9. These two serotypes were found in livestock and poultry, with swine serving as the major reservoir. The geographic distribution of pathogenic isolates was significantly different, where most of the strains were isolated from the cold northern areas, whereas some serotype O:3 strains were recovered from the warm southern areas. By the analysis of the data of the Ningxia Hui Autonomous Region, we find the phenomenon of 'concentric circle distribution' around animal reservoirs and human habitation. The clustering of PFGE showed that the patterns of the pathogenic strains isolated from diarrhea patients were identical compared to those from the animals in the same area, thus, suggesting that the human infection originated from the animals.
Wang
X
X
National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, P.O. Box 5, 102206, Changping, Beijing, China.
Cui
Z
Z
Jin
D
D
Tang
L
L
Xia
S
S
Wang
H
H
Xiao
Y
Y
Qiu
H
H
Hao
Q
Q
Kan
B
B
Xu
J
J
Jing
H
H
D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology; D000835:Animals, Wild / Q000382:microbiology; D002681:China / Q000453:epidemiology; D016000:Cluster Analysis; D004197:Disease Reservoirs / Q000382:microbiology / Q000662:veterinary; D016521:Electrophoresis, Gel, Pulsed-Field; D004783:Environmental Microbiology; D005516:Food Microbiology; D006801:Humans; D019081:O Antigens / Q000235:genetics; D016133:Polymerase Chain Reaction; D012703:Serotyping; D037521:Virulence Factors / Q000235:genetics*; D015009:Yersinia Infections / Q000453:epidemiology / Q000382:microbiology* / Q000662:veterinary; D015008:Yersinia enterocolitica / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*
D019081:O Antigens; D037521:Virulence Factors