Second messenger signaling: multiple receptors for NAADP.
The second messenger NAADP appears to have an essential role as a universal trigger of Ca(2+) signaling. Following on from previously published NAADP receptor candidates, recent work now describes the identification of a novel NAADP-sensitive Ca(2+) channel.
Guse
Andreas H
AH
The Calcium Signalling Group, Institute of Biochemistry and Molecular Biology I, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany. guse@uke.de
D015220:Calcium Channels / Q000737:chemistry / Q000378:metabolism*; D002460:Cell Line; D006801:Humans; D009249:NADP / Q000031:analogs & derivatives* / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000737:chemistry / Q000378:metabolism*; D019837:Ryanodine Receptor Calcium Release Channel / Q000737:chemistry / Q000378:metabolism; D015290:Second Messenger Systems / Q000502:physiology*
D015220:Calcium Channels; D011956:Receptors, Cell Surface; D019837:Ryanodine Receptor Calcium Release Channel; D009249:NADP; C024376:NAADP