title: Light emitting diodes versus compact fluorescent tubes for phototherapy in neonatal jaundice: a multi center randomized controlled trial.
abstract: OBJECTIVE
  To evaluate whether light-emitting diode (LED) phototherapy is as efficacious as compact fluorescent tube (CFT) phototherapy for the treatment of non-hemolytic jaundice in healthy term and late preterm neonates.
  
  
  METHODS
  Multi centre open label randomized controlled trial.
  
  
  METHODS
  Four tertiary care neonatal units.
  
  
  METHODS
  Healthy term and late preterm neonates with non-hemolytic jaundice.
  
  
  METHODS
  Single-surface LED or CFT phototherapy.
  
  
  METHODS
  Duration of phototherapy.
  
  
  RESULTS
  A total of 272 neonates were randomized to receive LED (n=142) or CFT (n=130) phototherapy. The baseline demographic and biochemical variables were similar in the two groups. The median duration of phototherapy (IQR) in the two groups was comparable (26 (22-36) h vs. 25(22-36) h; P=0.44). At any time point, a similar proportion of neonates were under phototherapy in the two groups (log-rank test, P=0.38). The rate of fall of serum total bilirubin (STB) during phototherapy and the incidence of failure of phototherapy were also not different. An equal proportion of neonates had a rebound increase in STB needing restarting of phototherapy. Side effects were rare, comparable in the two groups and included hypothermia, hyperthermia, rash, skin darkening and dehydration.
  
  
  CONCLUSIONS
  LED and CFT phototherapy units were equally efficacious in the management of non-hemolytic hyperbilirubinemia in healthy term and late preterm neonates.
authors: Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors: Praveen
authors: P
authors: Kumar
authors: Srinivas
authors: S
authors: Murki
authors: G K
authors: GK
authors: Malik
authors: Deepak
authors: D
authors: Chawla
authors: Ashok K
authors: AK
authors: Deorari
authors: N
authors: N
authors: Karthi
authors: Sreeram
authors: S
authors: Subramanian
authors: Jonnala
authors: J
authors: Sravanthi
authors: Pramod
authors: P
authors: Gaddam
authors: S N
authors: SN
authors: Singh
mesh_terms: D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000453:epidemiology / Q000628:therapy*; D053208:Kaplan-Meier Estimate; D008297:Male; D010789:Phototherapy / Q000295:instrumentation* / Q000379:methods; D018709:Statistics, Nonparametric