Epilepsy and temporal lobe injury after skull base proton beam therapy.
We present three patients who developed temporal lobe injury and epilepsy after proton beam therapy to the skull base. This particular form of treatment-related toxicity should be considered when treating skull base tumors.
Roda
Ricardo Horacio
RH
Department of Neurology, Room 5050, Outpatient Center, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, Maryland 21287, USA. rroda1@jhmi.edu
Gallia
Gary L
GL
Eberhart
Charles G
CG
Weingart
Jon D
JD
Laterra
John
J
D000328:Adult; D001921:Brain / Q000473:pathology; D002813:Chondrosarcoma / Q000150:complications* / Q000532:radiotherapy*; D002817:Chordoma / Q000150:complications* / Q000532:radiotherapy*; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000150:complications* / Q000532:radiotherapy*; D008875:Middle Aged; D011522:Protons; D011878:Radiotherapy / Q000009:adverse effects*; D019292:Skull Base Neoplasms / Q000150:complications* / Q000532:radiotherapy*; D013702:Temporal Lobe / Q000293:injuries*
D011522:Protons