Effect of older maternal age on the risk of spontaneous preterm labor: a population-based study.
To determine if older maternal age (35 years and older) at first birth was an independent risk factor for spontaneous preterm labor, we conducted a retrospective population-based cohort study. Using provincial perinatal data, we developed separate risk models for low- and high-risk women using multivariate logistic regression. We found that older maternal age exerted a direct and independent effect on spontaneous preterm labor for both nulliparous women with no preexisting chronic illnesses or pregnancy complications (low-risk) and nulliparous women who did not have any preexisting chronic illnesses, but developed one or more pregnancy complications (high-risk).
McIntyre
Safina Hassan
SH
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Newburn-Cook
Christine V
CV
O'Brien
Beverley
B
Demianczuk
Nestor N
NN
D000328:Adult; D017677:Age Distribution; D000416:Alberta / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D016015:Logistic Models; D008423:Maternal Age; D008875:Middle Aged; D007752:Obstetric Labor, Premature / Q000453:epidemiology*; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D018566:Pregnancy, High-Risk; D012307:Risk Factors; D016387:Women's Health