Asymmetric Friedel-Crafts reaction of N-heterocycles and nitroalkenes catalyzed by imidazoline-aminophenol-Cu complex.
Catalytic asymmetric Friedel-Crafts reaction of pyrrole with nitroalkenes was smoothly catalyzed by newly synthesized nitro-substituted imidazoline-aminophenol (1b)-Cu complex to give the adduct with up to 92% ee.
Yokoyama
Naota
N
Department of Chemistry, Graduate School of Science, Chiba University, Inage, Chiba 263-8522, Japan.
Arai
Takayoshi
T
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D048288:Imidazolines / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry
D000475:Alkenes; D006571:Heterocyclic Compounds; D048288:Imidazolines; D009942:Organometallic Compounds; D011758:Pyrroles