Cell-cycle control: don't supersize me.
Cells often grow to a certain cell size before entering mitosis and dividing. Two recent articles suggest that fission yeast cells sense their own size through the action of an intracellular gradient emanating from cell tips and a sensor at the cell middle.
Pan
Kally Z
KZ
Microbiology Department, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Chang
Fred
F
D002453:Cell Cycle / Q000502:physiology*; D018797:Cell Cycle Proteins / Q000378:metabolism; D048429:Cell Size; D008938:Mitosis / Q000502:physiology*; D009687:Nuclear Proteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D012568:Schizosaccharomyces / Q000166:cytology* / Q000502:physiology; D029702:Schizosaccharomyces pombe Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
D018797:Cell Cycle Proteins; D009687:Nuclear Proteins; D029702:Schizosaccharomyces pombe Proteins; C068689:wee1 protein, S pombe; D011505:Protein-Tyrosine Kinases; C542567:Cdr2 protein, S pombe; D017346:Protein Serine-Threonine Kinases