Direct aldol reactions catalyzed by intramolecularly folded prolinamide dendrons: dendrimer effects on stereoselectivity.
Dendritic effects on both the enantioselectivity and diastereoselectivity of the direct aldol reaction were observed for pyridine-2,6-dicarboxamide dendrons terminated with L-prolinamides.
Mitsui
Kazuhiko
K
Department of Chemistry, The Ohio State University, 100 W. 18th Ave., Columbus, OH 43210, USA.
Hyatt
Sarah A
SA
Turner
Daniel A
DA
Hadad
Christopher M
CM
Parquette
Jon R
JR
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D050091:Dendrimers / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity
D000447:Aldehydes; D050091:Dendrimers; C116609:3-hydroxybutanal; D011392:Proline; C056291:prolinamide