Novel zolpidem formulations.
Zolpidem is currently the global market leader in the hypnotic arena. Recently several novel zolpidem formulations have been launched in the U.S. or are in the preregistration development phase. These comprise an extended-release form, two types of sublingual formulations and an oral spray. The pharmacokinetic and pharmacodynamic effects of these formulations are reviewed.
Owen
Richard T
RT
Medical Information Dept., Prous Science, Barcelona, Spain. scientific.prousjournals@thomsonreuters.com
D000284:Administration, Oral; D000286:Administration, Sublingual; D000336:Aerosols; D003692:Delayed-Action Preparations; D004304:Dosage Forms; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology*; D011725:Pyridines / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology*; D000077334:Zolpidem
D000336:Aerosols; D003692:Delayed-Action Preparations; D004304:Dosage Forms; D006993:Hypnotics and Sedatives; D011725:Pyridines; D000077334:Zolpidem