Analysis of chemical constituents and taxonomic similarity of Salvia species in China using LC/MS.
Salvia species have an extensive distribution and a long history of medical use in China. In this study, chemical differences between different Salvia species were thoroughly investigated, and 86 constituents were characterized through a sensitive HPLC-DAD-ESI-MS (n) method. In total, 19 Salvia species were screened. Our study suggested that Ser. Brachylomae, Ser. Digitaloidites, Ser. Castaneae, and Ser. Miltiorrhizae were the sibling series (Ser. is short for series) and that Ser. Brachylomae, Ser. Maximowicziana, and Ser. Campanulatae were unique with regard to their constituents in addition to having componential affinity. This study offered a simple chemotaxonomy approach and a reasonable bioactivity interpretation of Salvia species.
Qiao
Xue
X
Department of Natural Medicines and the State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, PR China.
Zhang
Ying-Tao
YT
Ye
Min
M
Wang
Bao-Rong
BR
Han
Jian
J
Guo
De-an
DA
D002681:China; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D013058:Mass Spectrometry; D027544:Salvia / Q000737:chemistry* / Q000145:classification*; D013045:Species Specificity
D004365:Drugs, Chinese Herbal