Giant verrucous nodules in a patient with tuberculosis.
Sarcoidosis is a systemic inflammatory disorder characterized histologically by noncaseating granulomas in affected organs. Cutaneous manifestations of the disease such as papules, nodules, plaques, and ulcerations occur in approximately 25% of the patients. Sarcoidosis can present with multiple different morphologies including annular, psoriasiform, ichthyosiform, morpheaform, and verrucous. In this study, we report a 30-year-old African American man with a history of spinal tuberculosis as a child and slowly enlarging verrucous nodules that appeared at the age of 5 years. After an extensive infectious disease evaluation, the diagnosis of verrucous sarcoidosis was established with the presence of noncaseating granulomas and a completely negative workup for infectious etiologies.
Kannan
Swati
S
Section of Dermatology, Medical College of Georgia, Augusta, GA, USA.
Simpson
Gregory L
GL
Sheehan
Daniel J
DJ
Lesher
Jack L
JL
D000328:Adult; D002648:Child; D006801:Humans; D008297:Male; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology*; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*; D014399:Tuberculosis, Spinal / Q000150:complications*; D014860:Warts / Q000473:pathology