title: Collagenous fibroma (desmoplastic fibroblastoma) with a new translocation involving 11q12: a case report.
abstract: Collagenous fibroma (or desmoplastic fibroblastoma) is a rare, benign tumor usually centered in the subcutaneous tissue composed of spindle-shaped to stellate fibroblasts and myofibroblasts in a densely collagenous background. Three previous case reports have described a t(2;11)(q31;q12) in this entity. Herein, we report a case of collagenous fibroma of deep soft tissue with t(11;17)(q12;p11.2). The breakpoint at chromosome 11q12 appears to be pathogenetic in this rare neoplasm.
authors: Department of Pathology and Laboratory Medicine, University Hospital, New Jersey Medical School, 150 Bergen Street, Newark, NJ 07103, USA. amin_maghari2002@yahoo.com
authors: Amin
authors: A
authors: Maghari
authors: Naili
authors: N
authors: Ma
authors: Seena
authors: S
authors: Aisner
authors: Joseph
authors: J
authors: Benevenia
authors: Meera
authors: M
authors: Hameed
mesh_terms: D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics; D003094:Collagen / Q000378:metabolism*; D005260:Female; D005350:Fibroma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic
chemical_list: D003094:Collagen