title: Ultrastructure of human fetal sympathetic ganglia after permanganate fixation - absence of granular vesicles.
abstract: Midterm human fetal sympathetic ganglia were studied using the formaldehyde-induced fluorescence technique for demonstrating catecholamines, and after glutaraldehyde-OsO(4) or permanganate fixation for electron microscopy. The fluorescence technique indicated the presence of catecholamines in most of the developing neurons. After glutaraldehyde-OsO(4) fixation large granular vesicles were found in the perikarya, but a more specific technique for catecholamines, permanganate fixation, revealed no granular vesicles at this stage of development. This indicates that most of the catecholamines are loosely bound in a non-granular store during development.
authors: Department of Biomedical Sciences, University of Tampere, Tampere, Finland.
authors: A
authors: A
authors: Hervonen
authors: L
authors: L
authors: Kanerva
authors: H
authors: H
authors: Hervonen