title: Hemicellulose dressing versus rayon dressing in the re-epithelialization of split-thickness skin graft donor sites: a multicenter study.
abstract: The aim of this study was to compare the effectiveness of a hemicellulose dressing with that of rayon dressing in the healing of split-thickness skin graft donor sites. Twenty-eight patients were selected from five different hospitals and randomized into two groups: hemicellulose dressing group and rayon dressing group. All patients underwent split-thickness skin grafting for various reasons, and the skin graft donor site wounds were covered with hemicellulose dressing (n=14) or rayon dressing (n=14). The donor site was assessed on postoperative days 1, 7, 14, 21, and 28 for hyperemia, pruritus, pain, exudate level, and adherence of the wound dressing. At the 60-day follow-up visit, the donor site was assessed again for pruritus and pain. Touch-pressure, thermal, and pain sensibility tests were performed preoperatively and on postoperative day 60 together with the assessment of color and texture of the re-epithelialized area. In all patients, re-epithelialization was completed between 14 and 21 days after surgery. There were no significant differences between the two groups with regard to pain, hyperemia, pruritus, exudate, and final appearance (color and texture) of the skin graft donor site. The rayon dressing provided significantly better adherence than the hemicellulose dressing, and both dressings showed similar results with regard to the parameters evaluated when used in the treatment of split-thickness skin graft donor sites.
authors: Division of Plastic Surgery, Federal University of São Paulo-UNIFESP, and Vila Penteado General Hospital, Rua Napoleão de Barros 715, 4. andar, Vila Clementino, 04023-062 São Paulo, SP, Brazil. lydia.dcir@unifesp.epm.br
authors: Lydia M
authors: LM
authors: Ferreira
authors: Leila
authors: L
authors: Blanes
authors: Alfredo
authors: A
authors: Gragnani
authors: Daniela F
authors: DF
authors: Veiga
authors: Frederico P
authors: FP
authors: Veiga
authors: Gilka B
authors: GB
authors: Nery
authors: Gustavo Henrique H R
authors: GH
authors: Rocha
authors: Heitor C
authors: HC
authors: Gomes
authors: Mario G
authors: MG
authors: Rocha
authors: Regina
authors: R
authors: Okamoto
mesh_terms: D000328:Adult; D000368:Aged; D001458:Bandages; D002482:Cellulose; D005260:Female; D006801:Humans; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides; D011182:Postoperative Care; D011446:Prospective Studies; D016038:Skin Transplantation; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D011134:Polysaccharides; C007916:hemicellulose; D002482:Cellulose; C012024:rayon, purified