Insulin pump therapy for type 1 diabetes treatment in a girl with Down's syndrome.
We present the case of a 29.5-year-old girl with Down's syndrome, type 1 diabetes mellitus (DMT1), autoimmune thyroiditis and celiac disease starting on insulin pump therapy. After 22-month follow-up hemoglobin A1c dropped from 9% to 6.8%, even with a lower insulin requirement and no change in BMI.
Scaramuzza
Andrea E
AE
Department of Pediatrics, Azienda Ospedaliera, University of Milan, Ospedale Luigi Sacco, Milan, Italy. scaramuzza.andrea@hsacco.it
Giani
Elisa
E
Riboni
Sara
S
Spiri
Daniele
D
De Palma
Alessandra
A
Mameli
Chiara
C
Zuccotti
Gian Vincenzo
GV
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D050031:Hashimoto Disease / Q000150:complications; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007328:Insulin / Q000008:administration & dosage* / Q000031:analogs & derivatives / Q000627:therapeutic use; D000069036:Insulin Glargine; D007332:Insulin Infusion Systems; D049528:Insulin, Long-Acting; D016896:Treatment Outcome
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D000069036:Insulin Glargine; D049528:Insulin, Long-Acting