Applanation tonometry versus dynamic contour tonometry in eyes treated with latanoprost.
OBJECTIVE
To examine the differences between Goldmann Applanation Tonometry (GAT) and Dynamic Contour Tonometry (DCT) associated with latanoprost use.


METHODS
Twenty-four eyes (of 24 patients) treated with latanoprost monotherapy (latanoprost group, LG), 11 eyes (of 11 patients) not receiving prostaglandin analogs (nonlatanoprost group, NLG), and 20 eyes of 20 nonglaucomatous patients (control group, CG) were included. GAT, DCT, measurement of central corneal thickness and axial length of the eyeball were performed. The difference between GAT and DCT intraocular pressure (dIOP) was calculated. Differences in dIOP among LG, NLG, and CG and correlations of dIOP with other clinical parameters were examined.


RESULTS
dIOP was significantly higher in LG, compared with NLG or CG. The correlations of dIOP with axial length of the eyeball were statistically significant in the LG but not in NLG or CG. The correlations of dIOP with central corneal thickness, patients' age, and duration of latanoprost use (LG) were statistically not significant.


CONCLUSIONS
The fact that dIOP was significantly higher in LG, compared with NLG and CG implies that latanoprost may affect the biomechanical properties of the ocular walls.
Detorakis
Efstathios T
ET
Department of Ophthalmology, University Hospital of Heraklion, Crete, Greece. detorakis@hotmail.com
Arvanitaki
Vasiliki
V
Pallikaris
Ioannis G
IG
Kymionis
George
G
Tsilimbaris
Miltiadis K
MK
D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001699:Biometry; D003315:Cornea / Q000473:pathology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D000077338:Latanoprost; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D014065:Tonometry, Ocular / Q000379:methods*
D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost