title: PRP with subcorneal acantholysis: case report and review.
abstract: Although the clinical findings of pityriasis rubra pilaris (PRP) are striking, the microscopic diagnosis can be difficult because changes can be subtle and can overlap with other skin diseases. Suprabasal acantholysis can be seen in PRP, mimicking pemphigus vulgaris. We report a patient with PRP whose initial biopsies demonstrated subcorneal acantholysis mimicking pemiphigus foliaceus.
authors: Department of Pathology, Drexel College of Medicine, Philadelphia, PA 19130, USA. anita_sebastian@yahoo.com
authors: Anita
authors: A
authors: Sebastian
authors: Amy Beth
authors: AB
authors: Koff
authors: Lynne J
authors: LJ
authors: Goldberg
mesh_terms: D000051:Acantholysis / Q000175:diagnosis* / Q000188:drug therapy; D017255:Acitretin / Q000627:therapeutic use; D000368:Aged; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D010392:Pemphigus / Q000175:diagnosis; D010916:Pityriasis Rubra Pilaris / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin