[Case of pulmonary tuberculosis with miliary granules, mediastinal lymph node enlargement and elevation of soluble interleukin-2 receptor].
An 80-year-old woman suffered from fever and loss of appetite. Her chest X-ray showed mediastinal tumors and diffuse granular shadows in the bilateral lung fields. Elevations of sIL-2r and M-protein were present. HRCT showed numerous small granules in both lungs and mediastinal lymph node enlargement. Tuberculosis DNA was detected by PCR in her sputum. Later, Mycobacterium tuberculosis was cultured from her sputum. After she started anti-tuberculosis therapy, her general fatigue and elevation of sIL-2r improved gradually. Her chest X-ray revealed a decrease in the size of mediastinal lymph nodes and small granules.
Tabata
Hisako
H
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Hyogo, Japan. taba-h@hmj-net.hosp.go.jp
Mochizuki
Yoshiro
Y
Nakahara
Yasuharu
Y
Kawamura
Tetsuji
T
Sasaki
Shin
S
Tsukamoto
Hiroaki
H
D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000008:administration & dosage; D015415:Biomarkers / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D013902:Radiography, Thoracic; D015375:Receptors, Interleukin-2 / Q000097:blood*; D012995:Solubility; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy
D000995:Antitubercular Agents; D015415:Biomarkers; D007075:Immunoglobulin M; D015375:Receptors, Interleukin-2