title: [Cardiovascular risk and metabolic syndrome at the Toledo Area Study].
abstract: OBJECTIVE
  To know the anthropometric and clinical characteristics of a children population sample, to study the prevalence and concurrence of cardiovascular risk factors in that sample, and to define the prevalence of metabolic syndrome in that population considering the blood pressure, HDL cholesterol, and fasting glycemia values, as well as the anthropometrical measurements.
  
  
  METHODS
  The health care area of Toledo.
  
  
  METHODS
  Children aged 4 years included in the Toledo Area Study.
  
  
  METHODS
  A prospective study is performed on the metabolic syndrome-related cardiovascular risk factors in a sample of 58 children from the Toledo Area Study. Data on anthropometrical and lipoprotein profile at birth were obtained. The anthropometrical, lipoprotein, and biochemical data were compared with those from other populations; we also looked for possible differences between boys and girls. At the same time, we analyzed the association between several cardiovascular risk factors in that population (logistic regression model) and we set up the cut-off levels to define in the children population possible candidates to metabolic syndrome. These levels are in agreement with those from similar adolescent populations.
  
  
  RESULTS
  Among the risk factors, higher systolic and diastolic pressure values stand up in girls (93.93 -boys- vs 98.41 -girls- p = 0.058; 52.32 -boys- vs 57.27 -girls- p = 0.026, respectively), as well as the concurrence of high blood pressure and hypercholesterolemia in boys (almost 7%). The whole prevalence of candidates to MS was 10.9% (5 girls -9.1%- and 1 boy -1.8%-). A high percentage of boys (< 50%) presented a wrong diet from the perspective of dietary cardiovascular risk markers. The only statistically significant variable at 10% (p < 0.10) in the regression model was Apo AI.
  
  
  CONCLUSIONS
  It is relevant that the presence of MS is higher in girls and in those infants with a dyslipemic nonhypercholesterolemic profile at birth, which emphasizes the usefulness of cardiovascular risk factors prospection from early ages.
authors: Servicio de Farmacia, Hospital Virgen de la Salud, Toledo.
authors: J M
authors: JM
authors: Martínez Sesmero
authors: S
authors: S
authors: Bastida
authors: F J
authors: FJ
authors: Sánchez-Muniz
mesh_terms: D000293:Adolescent; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology