title: Malignant lymphoma in an atomic-bomb survivor.
abstract: Atomic bomb survivors outside of Japan are few and often hard to follow-up. Spinal malignant lymphoma among these survivors is rare in established studies from Japan or the United States. Here, we report an 81-year-old woman, who experienced the atomic bomb explosion in Nagasaki when she was 19 years old, who presented with papillary thyroid carcinoma when she was 70 years old. Both follicular lymphoma over the right elbow region and vertebral malignant lymphoma were found when she turned 81 years old. Bone scan did not show any increased uptake of isotope. However, thoracolumbar spine magnetic resonance imaging showed multiple infiltrative soft tissue masses involving vertebral bodies at the T10-11 level. Computed tomography-guided biopsy further showed lymphocyte infiltration. Fortunately, the neurological deficit was improved after chemotherapy. The diagnosis of malignant lymphoma in atomic bomb survivors should be more careful and aggressive, even when their bone scan results show negative findings. In addition, the authors suggest that atomic bomb survivors should be followed-up carefully throughout their entire life.
authors: Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Department of Surgery, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
authors: Cheng-Chia
authors: CC
authors: Lee
authors: Wei-Ming
authors: WM
authors: Chen
authors: Chueh-Chuan
authors: CC
authors: Yen
authors: Hong-Dar
authors: HD
authors: Wu
authors: Tain-Hsiung
authors: TH
authors: Chen
mesh_terms: D000368:Aged; D015174:Epidural Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007564:Japan; D008224:Lymphoma, Follicular / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009689:Nuclear Warfare; D017741:Survivors