Mirror image phage display--a method to generate D-peptide ligands for use in diagnostic or therapeutical applications.
Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.
Funke
Susanne Aileen
SA
Forschungszentrum Jülich, ISB-3, Jülich, Germany.
Willbold
Dieter
D
D015195:Drug Design; D008024:Ligands; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry* / Q000627:therapeutic use*; D013237:Stereoisomerism
D008024:Ligands; D019151:Peptide Library; D010455:Peptides