title: Retrograde transport of horseradish peroxidase in the rat's brain during halothane anesthesia.
abstract: The horseradish peroxidase (HRP) method was used to study the effect of halothane anesthesia on retrograde transport in the central nervous system. Rats received neostriatal injections of 30% HRP (0.3 microl) and were placed in inhalation chambers perfused with air or air containing 1% halothane for up to 24 h. Subsequently, the brain were examined at rostro-caudal levels of the presence and distribution of HRP-containing cells. The number and distribution of HRP-labelled cells appearing at each cranial level were compared in control and halothane-anesthetized animals as a function of time. The results suggest that retrograde transport in the central nervous system is unaffected during halothane anesthesia.
authors: Department of Anatomy, Northwestern University Medical School, 303 E. Chicago Ave., Chicago, IL 60611, USA.
authors: R M
authors: RM
authors: Clavier
authors: R E
authors: RE
authors: Hinkley