Synchronous bilateral breast cancer in a male patient following hormone therapy for prostate cancer.
We report an unusual case of bilateral, synchronous breast cancer in a male patient who had a history of estrogen therapy for prostate cancer. A 64-year-old Japanese man was diagnosed with T1N0M0 prostate cancer and received a total prostatectomy. Twenty months after the resection, the patient developed multiple bone metastases, and received radiation therapy, systemic chemotherapy, and hormone therapy for 15 months. After completing this treatment, he was diagnosed with T1N0M0 primary breast cancer in his left breast and underwent a modified mastectomy. Five months after the mastectomy he received systemic chemotherapy followed by estrogen therapy because of the progression of prostate cancer. Three months after this treatment, he was diagnosed with T1N0M0 primary breast cancer in his right breast. To the best of our knowledge, this is a rare case of synchronous bilateral male breast cancer following hormone therapy for prostate cancer.
Kijima
Yuko
Y
Department of Surgical Oncology, Breast and Endocrine Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan. ykijima@m3.kufm.kagoshima-u.ac.jp
Yoshinaka
Heiji
H
Hirata
Munetsugu
M
Umekita
Yoshihisa
Y
Matsukita
Sumika
S
Arima
Takashi
T
Nakagawa
Masayuki
M
Kumemura
Hizuru
H
Hamada
Nobuo
N
Kaneko
Koichi
K
Funasako
Yawara
Y
Natsugoe
Shoji
S
D000726:Androgen Antagonists / Q000009:adverse effects*; D018567:Breast Neoplasms, Male / Q000209:etiology*; D004967:Estrogens / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000188:drug therapy*
D000726:Androgen Antagonists; D004967:Estrogens; D017430:Prostate-Specific Antigen