Vasogenic edema in striatum following ingestion of glufosinate-containing herbicide.
Glufosinate-ammonium (GLA) is a broad-spectrum herbicide used worldwide. We report a patient who attempted suicide by ingesting a liquid herbicide containing GLA. A diffusion-weighted MRI showed cytotoxic edema in the hippocampus as well as vasogenic edema in the striata. To our knowledge, vasogenic edema caused by GLA-containing herbicide involving the striatum has not been reported in association with cytotoxic edema in the hippocampus. We assume that this herbicide affected the central nervous system via different mechanisms to produce both cytotoxic and vasogenic edema in the same patient.
Lee
Hui-Young
HY
Department of Internal Medicine, College of Medicine, Kangwon National University Hospital, Chuncheon, Kangwon-do, Korea.
Song
Seo-Young
SY
Lee
Seung-Hwan
SH
Lee
Seo-Young
SY
Kim
Sung-Hun
SH
Ryu
Sook-Won
SW
D000613:Aminobutyrates / Q000506:poisoning*; D001929:Brain Edema / Q000139:chemically induced* / Q000473:pathology*; D003342:Corpus Striatum / Q000473:pathology*; D005260:Female; D006540:Herbicides / Q000506:poisoning*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged
D000613:Aminobutyrates; D006540:Herbicides; C003121:phosphinothricin