Commercial premixed parenteral nutrition: Is it right for your institution?
Two-compartment premixed parenteral nutrition (PN) products are heavily promoted in the United States. These products may present safety advantages over PN solutions mixed by a local pharmacy, although clinical data to support this assertion are scarce. Multicompartment products can be labor-saving for pharmacy and therefore may be cost-effective for some institutions. Before adopting such products for use, an institution must determine that standardized PN solutions are acceptable for many or most of their patients compared with customized PN compounded specifically for individual patients. A larger selection of premixed products is available in Europe and some other parts of the world compared with the United States. Availability of a broader selection of products in the United States, including 3-compartment bags and a wider range of macronutrient concentrations and volumes, may make the use of such products more desirable in the future.
Miller
Sarah J
SJ
University of Montana, Saint Patrick Hospital, Skaggs School of Pharmacy, 2255 Flynn Lane, Missoula, MT 59808, USA. sarah.miller@umontana.edu
D003132:Commerce; D004339:Drug Compounding / Q000009:adverse effects / Q000191:economics; D064420:Drug-Related Side Effects and Adverse Reactions; D005060:Europe; D006801:Humans; D010288:Parenteral Nutrition / Q000009:adverse effects / Q000191:economics / Q000379:methods; D004364:Pharmaceutical Preparations / Q000191:economics / Q000592:standards; D010607:Pharmacy Service, Hospital / Q000191:economics / Q000592:standards*; D012015:Reference Standards; D014481:United States
D004364:Pharmaceutical Preparations