Imaging cardiac resynchronization therapy.
Although a prognostic benefit has been shown from cardiac resynchronization therapy, questions are often directed toward the prediction of symptomatic or functional benefit. Recent multicenter trials have shown the pitfalls of current mechanical markers of left ventricular synchrony, but these negative trial results have not marked the conclusion of efforts to predict outcome. Potential new contributors to the assessment of mechanical synchrony include echocardiographic and magnetic resonance techniques for the assessment of myocardial deformation. Nonsynchrony markers that seem promising include assessment of the location and extent of myocardial scar and imaging of the coronary venous and phrenic nerve anatomy.
Abraham
Theodore
T
Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Kass
David
D
Tonti
Giovanni
G
Tomassoni
Gery F
GF
Abraham
William T
WT
Bax
Jeroen J
JJ
Marwick
Thomas H
TH
D017023:Coronary Angiography; D003952:Diagnostic Imaging / Q000379:methods; D004452:Echocardiography; D004554:Electric Countershock; D006329:Heart Conduction System / Q000503:physiopathology; D006333:Heart Failure / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D018579:Patient Selection; D011237:Predictive Value of Tests; D014055:Tomography, Emission-Computed; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*