title: Spitz naevus is rare in Korea.
abstract: BACKGROUND
  Spitz naevi have not been widely studied in Asians.
  
  
  OBJECTIVE
  To compare the epidemiology and clinicopathological features of Spitz naevi in Koreans with lesions in western countries.
  
  
  METHODS
  In total, 80 Spitz naevi in 77 patients diagnosed over 10 years at 17 university hospitals in Korea were analysed.
  
  
  RESULTS
  The relative incidence of Spitz naevus vs. MM was 1 vs. 10.9. In most patients (75%) the Spitz naevi had been present for > 6 months. The size of the lesion was relatively large. Histologically, most of the lesions (54%) were the dermal type and pigmentation was common (49% of lesions). Immunohistochemical study found that all of the 34 lesions were positive for S-100 protein but only 14 (47%) were positive for HMB-45.
  
  
  CONCLUSIONS
  Spitz naevus is rare in Korea. The lesions were more commonly larger, pigmented, and of the dermal type than reported in western countries.
authors: Korean Dermatopathology Group, Department of Dermatology, School of Medicine, Ajou University, Suwon, Korea. maychan@ajou.ac.kr
authors: Y C
authors: YC
authors: Kim
authors: J E
authors: JE
authors: Do
authors: D
authors: D
authors: Bang
authors: B K
authors: BK
authors: Cho
authors: K H
authors: KH
authors: Cho
authors: J C
authors: JC
authors: Choi
authors: M B
authors: MB
authors: Kim
authors: M H
authors: MH
authors: Kim
authors: S Y
authors: SY
authors: Kim
authors: S N
authors: SN
authors: Kim
authors: J H
authors: JH
authors: Lee
authors: S J
authors: SJ
authors: Lee
authors: D H
authors: DH
authors: Shin
authors: J H
authors: JH
authors: Shin
authors: S J
authors: SJ
authors: Son
authors: K S
authors: KS
authors: Suh
authors: T Y
authors: TY
authors: Yoon
authors: C K
authors: CK
authors: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007723:Korea / Q000453:epidemiology; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000473:pathology; D008875:Middle Aged; D018332:Nevus, Epithelioid and Spindle Cell / Q000453:epidemiology / Q000473:pathology*; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology*; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor