title: Mechanical interferometry of nanoscale motion and local mechanical properties of living zebrafish embryos.
abstract: We present an interferometric imaging technique that permits local measurement of mechanical properties and nanomechanical motion in small living animals. Measurements of nanomechanical properties and spatially resolved pulsations of <60 nm were recorded for the developing eye of a living zebrafish (Danio rerio) embryo, an important model organism. We also used magnetic microreflectors to conduct contact nanomechanical indentation measurements of the stiffness of the embryonic eye.
authors: California NanoSystems Institute at UCLA, 570 Westwood Plaza, Los Angeles, California 90095, USA. jreed@cnsi.ucla.edu
authors: Jason
authors: J
authors: Reed
authors: Siddarth
authors: S
authors: Ramakrishnan
authors: Joanna
authors: J
authors: Schmit
authors: James K
authors: JK
authors: Gimzewski
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D004625:Embryo, Nonmammalian / Q000502:physiology* / Q000648:ultrastructure*; D005123:Eye / Q000648:ultrastructure; D005133:Eye Movements; D015027:Zebrafish