Post transplant anaplastic large T-cell lymphoma.
Post transplant lymphoproliferative disorders (PTLD) are a heterogeneous group of lymphoid proliferation that ranges from polyclonal hyperplasia to monoclonal malignant lymphoma. We report a 13-year-old boy who was diagnosed with PTLD in February 2007 after 3 1/2 years of deceased renal transplantation. We treated him with an adapted ACVBP (doxorubicin, cyclo-phosphamide, vincristine, bleomycin and prednisone) regimen. He responded well to the chemo-therapy without deterioration of graft function.
Azhir
Afshin
A
Department of Pediatrics, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. azhir@med.mui.ac.ir
Reisi
Nahid
N
Taheri
Diana
D
Adibi
Atoosa
A
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D003404:Creatinine / Q000097:blood; D003520:Cyclophosphamide / Q000627:therapeutic use; D016572:Cyclosporine / Q000008:administration & dosage; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D017728:Lymphoma, Large-Cell, Anaplastic / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D011183:Postoperative Complications / Q000276:immunology; D011241:Prednisone / Q000627:therapeutic use; D014751:Vindesine / Q000627:therapeutic use
D007166:Immunosuppressive Agents; D001761:Bleomycin; D004317:Doxorubicin; D016572:Cyclosporine; D003520:Cyclophosphamide; D003404:Creatinine; D009173:Mycophenolic Acid; D014751:Vindesine; D011241:Prednisone