An unreported side effect of risperidone in children: sinus arrest with long pauses causing syncope.
Risperidone has been reported as a well-tolerated antipsychotic in children. The most common side effects of risperidone are anxiety, headaches, insomnia, and agitation, which frequently appear with high doses. Although it is known that risperidone affects the cardiac conduction system, symptomatic bradycardia has not been reported previously in children. We report a child who developed syncope because of sinus arrest with long pauses (>3 seconds) with therapeutic doses of risperidone. This case suggests that close monitoring is mandatory even during therapeutic treatment with risperidone.
Olgun
Haşim
H
Division of Pediatric Cardiology, Ataturk, Universitesi Lojmanlari, 29. Blok No: 3/5, 25240, Erzurum, Turkey. holgun@atauni.edu.tr
Sepetcigil
Oguzhan
O
Karacan
Mehmet
M
Ceviz
Naci
N
D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D011595:Psychomotor Agitation / Q000150:complications / Q000188:drug therapy; D018967:Risperidone / Q000008:administration & dosage / Q000009:adverse effects*; D012893:Sleep Wake Disorders / Q000150:complications / Q000188:drug therapy; D013575:Syncope / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology
D014150:Antipsychotic Agents; D018967:Risperidone