title: Para-anastomotic haematoma volume predicts the presence of anastomotic extravasation after radical retropubic prostatectomy.
abstract: OBJECTIVE
  To determine the mechanism for delayed healing of the urinary anastomosis after radical retropubic prostatectomy (RRP).
  
  
  METHODS
  The volumes of the para-anastomotic haematoma (PHV) and anastomotic extravasation were measured by ultrasonography in 95 men after RRP. The performance characteristics of PHV for predicting urinary extravasation were ascertained and compared with that of postoperative blood loss, measured as the difference between the haematocrit immediately after RRP and that at discharge.
  
  
  RESULTS
  The sensitivity and specificity of PHV for predicting urinary extravasation at a threshold of 37 mL was 100% and 96%, respectively. PHV was superior to postoperative blood loss in predicting anastomotic extravasation, as shown by an area under the receiver operating curve of 0.99 vs 0.91, respectively.
  
  
  CONCLUSIONS
  Our findings provide compelling evidence that delayed healing of the anastomosis after RRP is due to distraction forces secondary to a pelvic haematoma. The accuracy of PHV as a predictor of anastomotic extravasation suggests that this measurement might replace cystography for assessing anastomotic integrity after RRP.
authors: Department of Urology, New York University Langone Medical Center, NYU Urology Associates, New York, NY, USA.
authors: Rebecca L
authors: RL
authors: O'Malley
authors: Shpetim
authors: S
authors: Telegrafi
authors: Juliana
authors: J
authors: Laze
authors: Herbert
authors: H
authors: Lepor
mesh_terms: D000714:Anastomosis, Surgical; D020878:Device Removal; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000000981:diagnostic imaging / Q000209:etiology*; D006400:Hematocrit; D006406:Hematoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000209:etiology*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000601:surgery*; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014546:Urinary Catheterization; D014945:Wound Healing / Q000502:physiology*