title: Mathematical modeling in metal metabolism: overview and perspectives.
abstract: A review of mathematical modeling in metal metabolism is presented. Both endogenous and exogenous metals are considered. Four classes of methods are considered: Petri nets, multi-agent systems, determinist models based on differential equations and stochastic models. For each, a basic theoretical background is given, then examples of applications are given, detailed and commented. Advantages and disadvantages of each class of model are presented. A special attention is given to determinist differential equation models, since almost all models belong to this class.
authors: Laboratoire de biomathématiques, E. A. 2498 & Plateau iB2, Département Santé publique et biostatistiques, faculté de Pharmacie, Université Paris Descartes, Paris 75006, France. emmanuel.curis@univ-paris5.fr
authors: Emmanuel
authors: E
authors: Curis
authors: Ioannis
authors: I
authors: Nicolis
authors: Jalil
authors: J
authors: Bensaci
authors: Patrick
authors: P
authors: Deschamps
authors: Simone
authors: S
authors: Bénazeth
mesh_terms: D000818:Animals; D006801:Humans; D008670:Metals / Q000378:metabolism*; D008962:Models, Theoretical
chemical_list: D008670:Metals