title: Carbohydrate metabolism differences between subgroup A1 and B2 strains of Bacillus anthracis as assessed by comparative genomics and functional genetics.
abstract: In France, Bacillus anthracis subgroup B2 strains do not metabolize starch or glycogen but can use gluconate, whereas subgroup A1 strains show the inverse pattern. Functional genetic analysis revealed that mutations in the amyS and gntK genes encoding an alpha-amylase and a gluconate kinase, respectively, were responsible for these phenotypes.
authors: Institut Pasteur, Unité Toxine et Pathogénie Bactériennes, (URA 2172, CNRS), 75724 Paris cédex 15, France.
authors: Patricia
authors: P
authors: Sylvestre
authors: Mary
authors: M
authors: Moya
authors: Michel
authors: M
authors: Haustant
authors: Josée
authors: J
authors: Vaissaire
authors: Michèle
authors: M
authors: Mock
mesh_terms: D001408:Bacillus anthracis / Q000235:genetics* / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D005602:France; D005798:Genes, Bacterial; D023281:Genomics; D005838:Genotype; D005942:Gluconates / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D053858:Metabolic Networks and Pathways / Q000235:genetics*; D009154:Mutation; D010641:Phenotype; D013213:Starch / Q000378:metabolism
chemical_list: D005942:Gluconates; D013213:Starch; D006003:Glycogen; C030691:gluconic acid