title: Gender differences of electrophysiological characteristics in focal atrial tachycardia.
abstract: Gender differences of supraventricular tachycardias such as atrioventricular nodal re-entry, atrioventricular re-entry, and atrial fibrillation have been reported. There is little evidence of the effect of gender on focal atrial tachycardia (FAT). The study consisted of 298 patients who were referred to this institution for radiofrequency catheter ablation of FAT from October 1992 to April 2008 and included 156 men (52%) and 142 women (48%). Men were significantly older than women (57.9 +/- 18.2 vs 47.2 +/- 19.0 years old, p <0.001). Women had more associated arrhythmias (17.0% vs 28.9%, p = 0.01), mostly due to an increased incidence of atrioventricular nodal re-entrant tachycardia. Men had more cardiovascular co-morbidities (19.9% vs 9.9%, p = 0.02), a mechanism of increased automaticity (19.1% vs 8.1%, p = 0.01), and nonparoxysmal tachycardia (14.7% vs 4.4%, p = 0.01). No gender differences were noted among FAT number, left atrial involvement, shortest tachycardia cycle, success rate of catheter ablation, or recurrence rate of FAT. Mean duration of follow-up was 63.2 +/- 47.5 months. Premenopausal women had a lesser cardiovascular co-morbidity (15.3% vs 4.3%, p = 0.04) and a greater incidence of a mechanism of increased automaticity (13.4% vs 2.9%, p = 0.03). In conclusion, gender differences in electrophysiologic characteristics were noted in FAT.
authors: Taipei Veterans General Hospital, National Yang-Ming University, Taipei, Taiwan.
authors: Yu-Feng
authors: YF
authors: Hu
authors: Jin-Long
authors: JL
authors: Huang
authors: Tsu-Juey
authors: TJ
authors: Wu
authors: Satoshi
authors: S
authors: Higa
authors: Chun-Ming
authors: CM
authors: Shih
authors: Ching-Tai
authors: CT
authors: Tai
authors: Yenn-Jiang
authors: YJ
authors: Lin
authors: Shih-Lin
authors: SL
authors: Chang
authors: Li-Wei
authors: LW
authors: Lo
authors: Tuan
authors: T
authors: Ta-Chuan
authors: Chien-Jong
authors: CJ
authors: Chang
authors: Wen-Chin
authors: WC
authors: Tsai
authors: Pi-Chang
authors: PC
authors: Lee
authors: Hsuan-Ming
authors: HM
authors: Tsao
authors: Sugako
authors: S
authors: Ishigaki
authors: Asuka
authors: A
authors: Oyakawa
authors: Shih-Ann
authors: SA
authors: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001283:Atrioventricular Node / Q000503:physiopathology; D017115:Catheter Ablation; D015331:Cohort Studies; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000601:surgery; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult