title: Interplay between fluoride and abrasivity of dentifrices on dental erosion-abrasion.
abstract: OBJECTIVE
  Eroded teeth are more susceptible to toothbrushing wear than sound teeth. We tested the hypothesis that fluoride and abrasivity of dentifrices can interact, modulating the development of erosive-abrasive lesions.
  
  
  METHODS
  Human enamel and root dentin specimens were submitted to cycles of demineralization, remineralization and toothbrushing using six dentifrices formulated with three different abrasivity levels: low (L), medium (M) and high (H); with (+F) and without (-F) fluoride. Surface loss was quantified by optical profilometry and compared among groups (alpha=0.05).
  
  
  RESULTS
  In dentin, it was ranked: L<M<H, for both +F and -F dentifrices. In enamel, +F dentifrices had similar results; however for -F formulations, M and H did not differ. Fluoride reduced surface loss in enamel, at all abrasive levels. In dentin, the same fluoride effect was observed but only for the low abrasive formulation.
  
  
  CONCLUSIONS
  Both fluoride and abrasivity were important modulators of enamel surface loss, while abrasivity had a higher impact than fluoride on dentin.
authors: Oral Health Research Institute, Department of Preventive and Community Dentistry, Indiana University School of Dentistry, 415 N. Lansing Street, Indianapolis, 46202-2876 IN, USA. ahara@iupui.edu
authors: Anderson T
authors: AT
authors: Hara
authors: Carlos
authors: C
authors: González-Cabezas
authors: Jonathan
authors: J
authors: Creeth
authors: Madhu
authors: M
authors: Parmar
authors: George J
authors: GJ
authors: Eckert
authors: Domenick T
authors: DT
authors: Zero
mesh_terms: D003743:Dental Enamel; D003799:Dental Stress Analysis; D003802:Dentifrices / Q000009:adverse effects*; D003804:Dentin; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D008963:Molar; D013499:Surface Properties; D014072:Tooth Abrasion / Q000209:etiology* / Q000517:prevention & control*; D017001:Tooth Demineralization / Q000209:etiology / Q000517:prevention & control; D014077:Tooth Erosion / Q000150:complications; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D003802:Dentifrices; D005459:Fluorides