title: Brain metastasis of non-small cell lung cancer presenting as sensorineural hearing loss and vertigo.
abstract: We report a case of lung cancer with multiple metastases to the brain and internal auditory canal. A 59-year-old man complained about persistent and progressive vertigo for 3 weeks with rapidly developing left-sided hearing loss and tinnitus. Bilateral intact eardrums and unsteady gait were noted on physical examination. There was no nystagmus. Pure tone audiometry showed left-sided sensorineural hearing loss. Magnetic resonance imaging of the brain revealed multiple intracranial tumors, including of the left-side internal auditory canal, which were interpreted as seeding of metastatic malignancy. Computed tomographic and bronchoscopic biopsy identified an asymptomatic primary pulmonary adenocarcinoma in the right upper lobe of the lungs. This was a rare case of asymptomatic primary pulmonary adenocarcinoma with brain metastases presenting with sudden hearing loss and vertigo.
authors: Department of Otolaryngology, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
authors: Chian-Shiang
authors: CS
authors: Gu
authors: Chia-Yu
authors: CY
authors: Liu
authors: Mao-Che
authors: MC
authors: Wang
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000556:secondary*; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D014717:Vertigo / Q000209:etiology*