title: Angiomatous reaction Kaposi-sarcoma-like as a side effect of topical corticosteroid therapy in lichen sclerosus of the penis.
abstract: Lichen sclerosus (LS) is a chronic inflammatory skin condition usually located in the anogenital area. Topical corticosteroid therapy is the first choice treatment which may arrest or delay the progression of the disorder. We report the case of a 74-year-old man presented with a 6-month history of nodular lesions localized on penis. The man had a previous history of genital lesions that had been diagnosed as LS and treated with long-term topical corticosteroid therapy. After 3 months of corticosteroid therapy, the patient observed the appearance of several nodular erythematous lesions on the penis with progressive disappearance of the clinical symptoms of LS. These purple to red asymptomatic angiomatoid nodules resembled the clinical features of Kaposi sarcoma.
authors: Department of Dermatology-Oncology, S. Gallicano Institute, IRCCS, Rome, Italy. catricala@ifo.it
authors: Caterina
authors: C
authors: Catricalà
authors: Samantha
authors: S
authors: Marenda
authors: Luca Maria
authors: LM
authors: Muscardin
authors: Pietro
authors: P
authors: Donati
authors: Andrea
authors: A
authors: Lepri
authors: Laura
authors: L
authors: Eibenschutz
mesh_terms: D000368:Aged; D002990:Clobetasol / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010409:Penile Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D010413:Penis / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000473:pathology
chemical_list: D005938:Glucocorticoids; C010893:clobetasone butyrate; D002990:Clobetasol