Experience with the treatment of argininosuccinic aciduria during pregnancy.
We present the details of the management and the outcome of a pregnancy of a woman affected with argininosuccinic aciduria. Management with a closely monitored, protein-restricted diet, supplemented with L-arginine, resulted in the birth of a healthy infant boy and an uneventful perinatal course for the mother.
Reid
L
L
Service de génétique médicale, Centre hospitalier universitaire de Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, J1H 5N4, Canada.
Perreault
E
E
Lafrance
G
G
Clarke
J T R
JT
D000328:Adult; D001120:Arginine / Q000008:administration & dosage; D001123:Argininosuccinate Lyase / Q000235:genetics; D056807:Argininosuccinic Aciduria / Q000150:complications* / Q000178:diet therapy* / Q000235:genetics; D018753:Diet, Protein-Restricted; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000178:diet therapy* / Q000201:enzymology / Q000235:genetics; D011256:Pregnancy Outcome; D011295:Prenatal Care
D001120:Arginine; D001123:Argininosuccinate Lyase