title: Epilepsy and temporal lobe injury after skull base proton beam therapy.
abstract: We present three patients who developed temporal lobe injury and epilepsy after proton beam therapy to the skull base. This particular form of treatment-related toxicity should be considered when treating skull base tumors.
authors: Department of Neurology, Room 5050, Outpatient Center, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, Maryland 21287, USA. rroda1@jhmi.edu
authors: Ricardo Horacio
authors: RH
authors: Roda
authors: Gary L
authors: GL
authors: Gallia
authors: Charles G
authors: CG
authors: Eberhart
authors: Jon D
authors: JD
authors: Weingart
authors: John
authors: J
authors: Laterra
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D002813:Chondrosarcoma / Q000150:complications* / Q000532:radiotherapy*; D002817:Chordoma / Q000150:complications* / Q000532:radiotherapy*; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000150:complications* / Q000532:radiotherapy*; D008875:Middle Aged; D011522:Protons; D011878:Radiotherapy / Q000009:adverse effects*; D019292:Skull Base Neoplasms / Q000150:complications* / Q000532:radiotherapy*; D013702:Temporal Lobe / Q000293:injuries*
chemical_list: D011522:Protons