title: Macrophage activation syndrome in malaria.
abstract: Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. We report an adolescent with severe Plasmodium falciparum malaria and MAS. He fulfilled six out of eight criteria required to diagnose hemophagocytic lymphohistiocytosis.
authors: Department of Paediatric Disciplines, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Room no. 218, Mawdiangdiang, Shillong 793018, India. rashnadass@rediffmail.com
authors: Rashna
authors: R
authors: Dass
authors: Himesh
authors: H
authors: Barman
authors: Sourabh Gohain
authors: SG
authors: Duwarah
authors: Vivek
authors: V
authors: Choudhury
authors: Pankaj
authors: P
authors: Jain
authors: Nayan Mani
authors: NM
authors: Deka
authors: Manjula
authors: M
authors: Murari
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis; D055501:Macrophage Activation Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008288:Malaria / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D008297:Male; D012720:Severity of Illness Index