title: [Comparative study between MBI (FICE) and magnification chromoendoscopy with indigo carmine in the differential diagnosis of neoplastic and non-neoplastic lesions of the colorectum].
abstract: BACKGROUND
  Multiband imaging (MBI)/Fuji Intelligent Color Enhancement (FICE) is a spectral image processing technology that helps in vivo diagnosis of colorectal neoplasias.
  
  
  OBJECTIVE
  To compare the diagnostic accuracy of the magnification with either the electronic chromoendoscopy or indigo carmine dye in the differential diagnosis of neoplastic and non-neoplastic colorectal lesions.
  
  
  METHODS
  Seventy five patients with 157 colorectal lesions were prospectively evaluated. The capillary pattern, as well as the pit pattern according to the Kudo classification, of colorectal lesions were evaluated by means of the FICE system. Absence and presence of meshed capillary networks were labeled as non-neoplastic and neoplastic lesions, respectively. Afterwards, indigo carmine 0.8% was instilled and a new evaluation of the pit pattern was carried out.
  
  
  RESULTS
  One hundred and sixteen of the 157 lesions were classified as positive meshed capillary network, 115 of them were confirmed histologically as neoplasia. Other 32 lesions out of 41 with negative meshed capillary network were non-neoplastic. Sensitivity, specificity and accuracy were, respectively, 92.7%, 97% and 93.6%. Pit patterns I and II were confirmed as non-neoplastic lesions, and patterns III to V were confirmed as neoplasias. Sensitivity, specificity and accuracy for the electronic chromoendoscopy were, respectively, 94.4%, 97% and 94.9%. Meanwhile, the figures for the magnification with indigo carmine were, respectively, 97.6%, 93.9% and 96.8%.
  
  
  CONCLUSIONS
  Both methods, either the MBI/FICE system or the use of indigo carmine dye with magnification, achieved a high accuracy for the differential diagnosis between neoplastic and non-neoplastic colorectal lesions.
authors: Serviço de Endoscopia Digestiva, Santa Casa de Caridade de Bagé, Bagé, RS, Brazil. clinica@endosantos.com.br
authors: Carlos Eduardo Oliveira dos
authors: CE
authors: Santos
authors: Júlio Carlos
authors: JC
authors: Pereira-Lima
authors: César Vivian
authors: CV
authors: Lopes
authors: Daniele
authors: D
authors: Malaman
authors: Artur A
authors: AA
authors: Parada
authors: Antônio David
authors: AD
authors: Salomão
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003108:Colonic Diseases / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology; D004396:Coloring Agents; D005260:Female; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D007203:Indigo Carmine; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012002:Rectal Diseases / Q000473:pathology*; D012680:Sensitivity and Specificity
chemical_list: D004396:Coloring Agents; D007203:Indigo Carmine