cDNA microarray analysis of esophageal cancer: discoveries and prospects.
Recent progress in molecular biology has revealed many genetic and epigenetic alterations that are involved in the development and progression of esophageal cancer. Microarray analysis has also revealed several genetic networks that are involved in esophageal cancer. However, clinical application of microarray techniques and use of microarray data have not yet occurred. In this review, we focus on the recent developments and problems with microarray analysis of esophageal cancer.
Shimada
Yutaka
Y
Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. yshimada@med.u-toyama.ac.jp
Sato
Fumiaki
F
Shimizu
Kazuharu
K
Tsujimoto
Gozoh
G
Tsukada
Kazuhiro
K
D000230:Adenocarcinoma / Q000235:genetics; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001471:Barrett Esophagus / Q000235:genetics; D002294:Carcinoma, Squamous Cell / Q000235:genetics; D045744:Cell Line, Tumor; D003131:Combined Modality Therapy; D018450:Disease Progression; D004938:Esophageal Neoplasms / Q000235:genetics* / Q000401:mortality / Q000628:therapy; D020869:Gene Expression Profiling; D006801:Humans; D008207:Lymphatic Metastasis; D016571:Neural Networks, Computer; D020411:Oligonucleotide Array Sequence Analysis; D025341:Principal Component Analysis; D011379:Prognosis; D011879:Radiotherapy Dosage
D000970:Antineoplastic Agents