Kaposi's sarcoma: a presenting manifestation of HIV infection in an Indian.
Kaposi's sarcoma (KS) is a multifocal neoplastic proliferation of endothelial cells predominantly involving skin and other organs. HIV-associated Kaposi's sarcoma has been rarely reported from India. A 38-year-old male presented with persistent swelling on the left lower limb for one year along with multiple erythematous to dusky papules and plaques of one and half months duration and swelling and black discoloration of right lower limb for one month. Cutaneous examination revealed numerous skin colored and erythematous papules and plaques distributed on the left lower limb on the anteromedial aspect and verrucous plaque on the left sole. Multiple erythematous, grouped papules were present over the soft palate. Skin biopsy showed numerous slit like spaces dissecting into the collagen of the upper and mid-dermis along with 'promontory sign' suggestive of Kaposi's sarcoma. Patient was found to be HIV-positive by ELISA test.
Kharkar
V
V
Department of Dermatology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India. vidyakharkar@gmail.com
Gutte
Rameshwar M
RM
Khopkar
U
U
Mahajan
S
S
Chikhalkar
S
S
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D015497:HIV-1; D006801:Humans; D007194:India; D008297:Male; D012514:Sarcoma, Kaposi / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy