[An analysis on prognostic factors of hilar cholangiocarcinoma].
OBJECTIVE
To investigate the influencing factors on the prognosis of hilar cholangiocarcinoma.


METHODS
The clinical data were retrospectively analyzed in 86 cases of hilar cholangiocarcinoma admitted into our hospital from Jan. 2004 to July. 2008.


RESULTS
Of 86 cases with hilar cholangiocarcinoma, the mean survival time was 13.7 +/- 2.3 months, 1-year survival 57.3% and 3-year survival 29.7%. The mean survival time in patients with resection operation (19.4 +/- 2.2 months) was significantly longer than those with no operation (7.2 +/- 1.2 months) (P < 0.05). The mean survival time in patients with non-vascular resection group (23.4 +/- 2.1 months) was significantly longer than those with portal vein resection alone group (15.3 +/- 1.4 months) and hepatic artery resection group (9.3 +/- 0.9 month) (P < 0.05). Cox regression analysis showed that staging, tumor diameter and operative were the dependent prognosis factors while pathologic type, vascular resection and age not the dependent prognosis factors.


CONCLUSIONS
The prognosis of hilar cholangiocarcinoma correlates with operative approach, clinical stage and tumor diameter. A surgeon must be cautious to choose the surgical approach for treatment.
Zhou
Li-Xin
LX
Department of Hepatobiliary Pancreatic Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China. zhoulxin8k@126.com
Zhang
Ze-Wei
ZW
Xu
Zhi-Yuan
ZY
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017734:Bile Ducts, Extrahepatic; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome