title: Altered distribution of plasma platelet-activating factor acetylhydrolase between high-density lipoprotein and low-density lipoprotein in patients with polycystic ovary syndrome.
abstract: To investigate the association of plasma platelet-activating factor (PAF) acetylhydrolase, high-density lipoprotein-associated PAF acetylhydrolase, and low-density lipoprotein-associated PAF acetylhydrolase activities with metabolic features in patients with polycystic ovary syndrome (PCOS) in Han Chinese women, 141 patients with PCOS and 140 healthy controls were recruited in this case-control study. The results of our study showed that the presence of the changed plasma PAF acetylhydrolase activity and distribution in women with PCOS could contribute to the low-grade chronic inflammation and increased risk of atherosclerosis in these patients.
authors: Laboratory of Genetic Disease and Perinatal Medicine, West China Second Hospital, Sichuan University, Chengdu, People's Republic of China.
authors: Ping
authors: P
authors: Fan
authors: Hong-Wei
authors: HW
authors: Liu
authors: De-Hua
authors: DH
authors: Wan
authors: You
authors: Y
authors: Li
authors: Qi
authors: Q
authors: Song
authors: Huai
authors: H
authors: Bai
mesh_terms: D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase / Q000097:blood*; D000328:Adult; D050197:Atherosclerosis / Q000453:epidemiology* / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007249:Inflammation / Q000453:epidemiology / Q000378:metabolism; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology* / Q000378:metabolism*; D011247:Pregnancy; D012307:Risk Factors; D055815:Young Adult
chemical_list: D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase