Synthesis of cyclopamine using a biomimetic and diastereoselective approach.
Giannis
Athanassios
A
Institut für Organische Chemie, Fakultät für Chemie und Mineralogie, Universität Leipzig, Johannisallee 29, 04103 Leipzig, Germany. giannis@uni-leipzig.de
Heretsch
Philipp
P
Sarli
Vasiliki
V
Stössel
Anne
A
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D032701:Biomimetics / Q000379:methods*; D053823:Hedgehog Proteins / Q000037:antagonists & inhibitors; D006801:Humans; D015398:Signal Transduction / Q000187:drug effects; D013237:Stereoisomerism; D014704:Veratrum Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000970:Antineoplastic Agents; D053823:Hedgehog Proteins; D014704:Veratrum Alkaloids; C000541:cyclopamine