Lymphoplasmacytic lymphoma with Waldenstrom's macroglobulinemia as a reason for peripheral arterial perfusion disorders.
Peripheral arterial perfusion disorders are often caused by embolism and thrombosis induced by diseases of the cardiovascular system. We report about a case of a 42-year-old female with peripheral arterial perfusion disturbances of the digital arteries caused by Waldenstrom s disease due to high plasma viscosity. Our patient presented with elevated plasma viscosity (1.34 mPA) and therefore plasmapheresis was necessary. Plasma separation is the most effective acute treatment for symptomatic hyperviscosity syndrome. In a second step patients with clinical symptoms of M. Waldenstrom have to be treated by chemotherapy.
Zgouras
D
D
Department of Internal Medicine, Division of Vascular Medicine, J. W. Goethe-University Hospital, Frankfurt/Main, Germany. d.zgouras@googlemail.com
Engels
K
K
Lindhoff-Last
E
E
D000328:Adult; D000527:Alprostadil / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001706:Biopsy; D001797:Blood Protein Electrophoresis; D001809:Blood Viscosity / Q000502:physiology*; D001853:Bone Marrow / Q000473:pathology; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D005385:Fingers / Q000098:blood supply* / Q000473:pathology*; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000097:blood; D007147:Immunoglobulin Light Chains / Q000097:blood; D007146:Immunoglobulin lambda-Chains / Q000097:blood; D007511:Ischemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D009336:Necrosis; D016491:Peripheral Vascular Diseases / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color; D014665:Vasodilator Agents / Q000627:therapeutic use; D008258:Waldenstrom Macroglobulinemia / Q000097:blood / Q000150:complications* / Q000175:diagnosis
D000925:Anticoagulants; D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D014665:Vasodilator Agents; D000527:Alprostadil