The Cirque du Soleil of Golgi membrane dynamics.
The role of lipid metabolic enzymes in Golgi membrane remodeling is a subject of intense interest. Now, in this issue, Schmidt and Brown (2009. J. Cell Biol. doi:10.1083/jcb.200904147) report that lysophosphatidic acid-specific acyltransferase, LPAAT3, contributes to Golgi membrane dynamics by suppressing tubule formation.
Bankaitis
Vytas A
VA
Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. vytas@med.unc.edu
D008243:1-Acylglycerophosphocholine O-Acyltransferase / Q000378:metabolism*; D000818:Animals; D006056:Golgi Apparatus / Q000201:enzymology* / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007425:Intracellular Membranes / Q000201:enzymology / Q000648:ultrastructure; D007527:Isoenzymes / Q000378:metabolism; D050356:Lipid Metabolism; D008958:Models, Molecular
D007527:Isoenzymes; D008243:1-Acylglycerophosphocholine O-Acyltransferase