The evolution of transdermal/ topical overactive bladder therapy and its benefits over oral therapy.
Multiple antimuscarinic agents are available for the treatment of overactive bladder. Many of the agents have undergone reformulation in an attempt to improve patient adherence and drug tolerability. Oxybutynin evolved from an immediate-release pill to a once-daily oral preparation, and is now available as a transdermal patch and gel. This article discusses the clinical impact of oxybutynin reformulation and reviews the evolution and benefits of transdermal therapy.
Macdiarmid
Scott A
SA
Alliance Urology Specialists, Bladder Control and Pelvic Pain Center Greensboro, NC.