title: Sickle cell-induced ischemic colitis.
abstract: Sickle cell-induced ischemic colitis is a rare yet potentially fatal complication of sickle cell anemia. Frequent pain crises with heavy analgesia may obscure and prolong this important diagnosis. Our patient was a 29-year-old female with sickle cell disease who was admitted with left lower quadrant abdominal pain. A diagnostic workup, including chemistries, complete blood count, blood cultures, chest x-ray, computerized tomography scanning, and colonoscopy, was performed to identify the etiology of her symptoms. This case highlights the importance of differentiating simple pain crisis from more serious and life-threatening ischemic bowel. A review of the literature compares this case to others reported and gives a method for diagnosing and treating this complication of sickle cell disease.
authors.affiliation: Section of General Internal Medicine, Tulane University School of Medicine, 1430 Tulane Ave, SL-16, New Orleans, LA 70112, USA.
authors.forename: Camille L
authors.initials: CL
authors.lastname: Stewart
authors.forename: Geraldine E
authors.initials: GE
authors.lastname: Ménard
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D017091:Colitis, Ischemic / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans