Developmental biology: Pipe's smoking guns.
The formation of the dorso-ventral body pattern of Drosophila involves the restricted activation of a serine protease cascade in the extracellular space between the egg shell and the embryo. Now, the first molecular links have been identified between ventral gene expression during oogenesis and the activation of the protease cascade in the early embryo.
Schüpbach
Trudi
T
HHMI/Dept. of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. schupbac@princeton.edu
D000818:Animals; D019521:Body Patterning / Q000502:physiology; D004330:Drosophila / Q000196:embryology; D005110:Extracellular Space / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D012697:Serine Endopeptidases / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
D012697:Serine Endopeptidases