Construction of a DNA nano-object directly demonstrates computation.
We demonstrate a computing method in which a DNA nano-object representing the solution of a problem emerges as a result of self-assembly. We report an experiment in which three-vertex colorability for a six-vertex graph with nine edges is solved by constructing a DNA molecule representing the colored graph itself. Our findings show that computation based on "shape processing" is a viable alternative to symbol processing when computing by molecular self-assembly.
Wu
Gang
G
Department of Chemistry, New York University, New York, NY 10003, USA. gw335@nyu.edu
Jonoska
Natasha
N
Seeman
Nadrian C
NC
D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004270:DNA, Circular / Q000737:chemistry / Q000235:genetics; D004277:DNA, Single-Stranded / Q000737:chemistry / Q000235:genetics; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry; D009690:Nucleic Acid Conformation
D004270:DNA, Circular; D004277:DNA, Single-Stranded; D004247:DNA