Self-assembling, dynamic alphaPNAs.
In the recent report published in Science, Ghadiri and coworkers describe dynamic tPNAs, alphaPNA derivatives with a nucleobase attached via a thioester bond that are a step forward toward self-repairing and replicating molecules.
Nielsen
Peter E
PE
Department of Cellular & Molecular Medicine, The Panum Institute, University of Copenhagen, Blegdamsvej 3c, Copenhagen DK 2200N, Denmark. ptrn@sund.ku.dk
D004151:Dipeptides / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D018716:Molecular Mimicry; D015394:Molecular Structure; D055601:Organic Chemistry Phenomena; D020135:Peptide Nucleic Acids / Q000737:chemistry*
D004151:Dipeptides; D004952:Esters; D020135:Peptide Nucleic Acids