title: Anterior segment optical coherence tomography as a screening tool for the assessment of the anterior segment angle.
abstract: OBJECTIVE
  Anterior segment optical coherence tomography (AS-OCT) is an alternative method for the assessment of angle width. The purpose of this study is to assess the accuracy of AS-OCT for detecting occludable angles and compare the results of high- and low-resolution images with gonioscopy.
  
  
  METHODS
  Visante AS-OCT (Carl Zeiss Meditec, Dublin, CA) images of 303 eyes (155 patients) presenting between February 1 and July 15, 2007, were retrospectively analyzed. Angle recess area (ARA) and angle opening distances (AOD) at 250, 500, and 750 microm were measured and correlated with the corresponding gonioscopic measurements.
  
  
  RESULTS
  AS-OCT parameters showed a nonlinear relationship with gonioscopy, ARA having the highest correlation. Correlations between high- and low-resolution images were modest. Cut-off values were 0.180 mm2 (70.3% sensitivity, 87.4% specificity) for ARA and 0.264 mm (71.8% sensitivity, 84.8% specificity) for AOD at 500 microm.
  
  
  CONCLUSIONS
  AS-OCT appears to be a promising screening tool for narrow angles.
authors.affiliation: University of California, San Francisco, Department of Ophthalmology, San Francisco, CA 94143-0730, USA.
authors.forename: Melike
authors.initials: M
authors.lastname: Pekmezci
authors.forename: Travis C
authors.initials: TC
authors.lastname: Porco
authors.forename: Shan C
authors.initials: SC
authors.lastname: Lin
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006068:Gonioscopy; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence; D014792:Visual Acuity