Medullary thyroid carcinoma metastatic to skin.
Cutaneous metastases are a rarity, even more so when they arise from a medullary thyroid carcinoma (MTC) which accounts for only 8% of all thyroid cancers. MTC arises from C-cells that produce calcitonin, and it most commonly metastasizes to lymph nodes in the neck. Distant metastases of MTC may involve bone, lung and liver. We report a case of a 56-year-old man, who presented with an ulcerated, nodular lesion on his scalp that proved to be a metastasis from his MTC diagnosed 2 years earlier. Cutaneous metastases from MTC generally signify widespread disease and carry a poor prognosis. A case discussion and relevant review of the literature is provided.
Nashed
Catherine
C
Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, Livingston, NJ 07039, USA.
Sakpal
Sujit Vijay
SV
Cherneykin
Sergey
S
Chamberlain
Ronald Scott
RS
D018276:Carcinoma, Medullary / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000556:secondary; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary; D013964:Thyroid Neoplasms / Q000473:pathology*