A minor, sweet cucurbitane glycoside from Siraitia grosvenorii.
A minor, sweet cucurbitane-glycoside, named iso-mogroside V (1), was isolated from Luo Han Guo (Siraitia grosvenorii (Swingle) C. Jeffery) along with five previously reported mogrosides. The structure of iso-mogroside V, 3-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-mogrol-24-O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->6)]beta-D-glucopyranoside, was established on the basis of extensive 2D-NMR (COSY, TOCSY, NOESY, HSQC, and HMBC) and LCMS analyses. The five known mogrosides were identified as mogroside V (2), 11-oxo-mogroside V (3), siamenoside I (4), mogrosides IVa (5) and IVe (6). Iso-mogroside V was determined to be approximately 500 times sweeter than 0.5% (w/v) sucrose.
Jia
Zhonghua
Z
Natural Products Research, Science and Technology, Givaudan Flavors Corporation, 1199 Edison Drive, Cincinnati, Ohio 45216, USA. Zhonghua.jia@givaudan.com
Yang
Xiaogen
X
D006027:Glycosides / Q000737:chemistry*; D015394:Molecular Structure; D012503:Saponins / Q000737:chemistry*; D013549:Sweetening Agents / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
D006027:Glycosides; D012503:Saponins; D013549:Sweetening Agents; D014315:Triterpenes; C514277:cucurbitane; C543279:isomogroside V