title: [Clinical analysis of the diagnosis of laryngeal tuberculosis].
abstract: OBJECTIVE
  To explore the clinical characteristic and diagnosis of modern laryngeal tuberculosis.
  
  
  METHODS
  A retrospective research among 33 patients of laryngeal tuberculosis, with definitive pathological result, had been done in the laryngeal-endoscope room in our department.
  
  
  RESULTS
  The main symptoms of laryngeal tuberculosis are hoarseness and sore throat. Most of the patients did not accompany with pulmonary tuberculosis (TB) (63.6%). Few of them accompany with low-grade fever, night sweat and malnutrition (24.2%). There are three types in the laryngeal-endoscope vision: edema type, hyperplasia type and ulcer exudation type. The positive rates of PPD and phlegm bacteria examination are respectively 87.9% and 68.4%. There can be seen in the pathological slides the interstitial phagocytes and giant cell reaction. Granuloma consisting of epithelioid cell and Langhans' cells is coexistent with necrotic tissue. Cheese necrosis is the typical characteristic of the disease.
  
  
  CONCLUSIONS
  Severe local symptoms of laryngeal with slightly general symptoms are the clinical characteristics of modern laryngeal tuberculosis. The diagnosis of it depends mainly on the process of the disease, laryngeal-endoscope examination and PPD examination combined with phlegm bacteria examination. And the final diagnosis is based on the pathological biopsy and tubercular bacillus culturing.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, First Hospital, Jiaotong University, Shanghai, 200080, China. likeyong@yahoo.com.cn
authors.forename: Ningjun
authors.initials: N
authors.lastname: Zhao
authors.forename: Yajing
authors.initials: Y
authors.lastname: Sun
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014387:Tuberculosis, Laryngeal / Q000175:diagnosis*