title: Cerebral revascularization using cadaveric vein grafts.
abstract: BACKGROUND
  Use of cadaveric cryopreserved saphenous vein grafts (CSVGs) has been described for peripheral vascular and coronary revascularization. The aim of this study is to recognize CSVGs as a potential alternative to autologous conduits for extracranial-intracranial (EC-IC) bypass in patients without available or suitable saphenous vein graft or radial artery. We report the short-term patency rate of CSVGs in EC-IC bypass.
  
  
  METHODS
  We present our preliminary experience in 10 patients using CSVG for cerebral revascularization. Data regarding operative indications, patient demographics, and bypass patency were collected.
  
  
  RESULTS
  The average age was 56 years old with equal sex distribution. The indications for the procedure were giant aneurysms in 7 patients, medically refractory vertebrobasilar ischemia in 2, and a skull base tumor in 1. ABO/Rh blood group compatible CSVG was used in each case. Postoperative angiography demonstrated patency in all cases. Quantitative magnetic resonance angiography was performed in 8 patients, demonstrating a mean bypass flow of 109 mL/min +/- 19 mL/min (mean +/- SE).
  
  
  CONCLUSIONS
  Use of CSVG for EC-IC bypass has not previously been reported. In our series, the short-term patency rate was 100%, better than that found in cardiac and peripheral vascular series, possibly because of the higher flow in EC-IC bypasses. Our preliminary experience suggests that CSVGs may be an option in patients without available autologous conduits, although longer follow-up is needed to assess long-term patency.
authors.affiliation: Department of Neurosurgery, University of Illinois at Chicago, IL 60612-5970, USA.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Mery
authors.forename: Sepideh
authors.initials: S
authors.lastname: Amin-Hanjani
authors.forename: Fady T
authors.initials: FT
authors.lastname: Charbel
mesh_terms: D000328:Adult; D000368:Aged; D002102:Cadaver; D002536:Cerebral Arteries / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D002548:Cerebral Revascularization / Q000379:methods*; D002560:Cerebrovascular Circulation / Q000502:physiology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D011859:Radiography; D020127:Recovery of Function / Q000502:physiology; D012501:Saphenous Vein / Q000033:anatomy & histology / Q000502:physiology / Q000637:transplantation*; D019292:Skull Base Neoplasms / Q000150:complications; D016378:Tissue Transplantation / Q000379:methods*; D016896:Treatment Outcome; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery