title: [Clinical evaluation of the antioxidant activity of astragalus in women with gestational diabetes].
abstract: OBJECTIVE
  To evaluate the antioxidant activity of astragalus and its therapeutic effect on gestational diabetes.
  
  
  METHODS
  Eighty-four pregnant women with gestational diabetes were divided into insulin and insulin plus astragalus groups after regular dietary control and insulin treatment to maintain stable blood glucose level. The 43 patients in insulin group received insulin injection, whereas the 41 patients in the other group received treatment with both insulin and astragalus. The SOD activity, MDA level, blood lipids and renal function were determined in both groups after the treatments.
  
  
  RESULTS
  The patients with both insulin and astragalus treatments showed significantly increased serum SOD activity and decreased MDA level, renal function and blood lipids in comparison with those with exclusive insulin treatment.
  
  
  CONCLUSIONS
  Astragalus can effectively control blood glucose, reduce the free radicals, and promote the antioxidative activity, and may play a role in the prevention and treatment of gestational diabetes.
authors.affiliation: Department of Gynecology and Obstetrics, Guangdong Women and Children's Hospital and Heath Institute, Guangzhou 510010, China.
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Liang
authors.forename: Feng
authors.initials: F
authors.lastname: Hou
authors.forename: Yong-Li
authors.initials: YL
authors.lastname: Ding
authors.forename: Wen-Ni
authors.initials: WN
authors.lastname: Zhang
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Huang
authors.forename: Bi-Yun
authors.initials: BY
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D027883:Astragalus Plant; D016640:Diabetes, Gestational / Q000188:drug therapy* / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008315:Malondialdehyde / Q000378:metabolism; D010084:Oxidation-Reduction; D008517:Phytotherapy; D011247:Pregnancy; D013482:Superoxide Dismutase / Q000378:metabolism; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D008315:Malondialdehyde; D013482:Superoxide Dismutase