Sequence-specific 1H, 13C, and 15N resonance assignments of GRP1 PH domain.
The carboxy-terminal pleckstrin homology (PH) domain recruits GRP1 to the plasma membrane through the specific binding to phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)]. Here, we describe backbone and side chain assignments of the GRP1 PH domain determined by triple resonance experiments.
He
Ju
J
Department of Pharmacology, University of Colorado Health Sciences Center, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Kutateladze
Tatiana G
TG
D000595:Amino Acid Sequence; D002247:Carbon Isotopes / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008969:Molecular Sequence Data; D009587:Nitrogen Isotopes / Q000737:chemistry; D017434:Protein Structure, Tertiary; D011522:Protons; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry*
D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D011522:Protons; D018160:Receptors, Cytoplasmic and Nuclear; C040985:phosphatidylinositol receptors