title: Endothelial keratoplasty: historical perspectives, current techniques, future directions.
abstract: Endothelial keratoplasty (EK) has recently emerged as an alternative to penetrating keratoplasty (PK) for patients with endothelial diseases, including Fuchs' endothelial dystrophy, pseudophakic bullous keratopathy, and corneal graft failure. EK provides distinct advantages over PK, in that it is a less invasive procedure and leads to more rapid recovery of vision. Additionally, this procedure does not require long-term corneal sutures, eliminating problems with suture breakage, suture abscesses, astigmatism, and wound dehiscence. Disadvantages of EK include the need for specially prepared donor tissue and additional surgeon training or experience. In this review we discuss the history of EK, recent advances that have led to its widespread use, limits and complications of the procedure, and areas for future improvement.
authors.affiliation: Cornea and External Diseases, University of New Mexico, Albuquerque, NM, USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Rose
authors.forename: Clare
authors.initials: C
authors.lastname: Kelliher
authors.forename: Albert S
authors.initials: AS
authors.lastname: Jun
mesh_terms: D017690:Cell Transplantation; D003316:Corneal Diseases / Q000601:surgery; D016039:Corneal Transplantation / Q000266:history / Q000379:methods / Q000639:trends; D003886:Descemet Membrane / Q000601:surgery*; D004728:Endothelium, Corneal / Q000637:transplantation*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D011183:Postoperative Complications; D014019:Tissue Donors; D016896:Treatment Outcome; D014792:Visual Acuity