title: Intraocular pressure changes during injection of microincision and conventional intraocular lenses through incisions smaller than 3.0 mm.
abstract: OBJECTIVE
  To compare intraocular pressure (IOP) during insertion of a new microincision intraocular lens (IOL) (Akreos AO MI60) and a conventional IOL (AcrySof Natural SN60AT) and to determine the minimum incision sizes for insertion in a cadaver eye model.
  
  
  METHODS
  John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
  
  
  METHODS
  After phacoemulsification in phakic cadaver eyes, multiple IOL insertions were attempted through 1.8 mm to 2.5 mm wounds. The final incision size and insertion success were evaluated in each case. A pressure transducer placed in the vitreous cavity measured real-time IOP changes (100 readings per second), including the mean and peak IOP during IOL implantation.
  
  
  RESULTS
  The minimum incision size for the microincision IOL insertion was 1.9 mm using a wound-assisted technique and 2.2 mm using a cartridge-insertion technique. The minimum incision size for wound-assisted implantation of the conventional IOL was 2.4 mm. During successful implantation, the mean and peak IOPs were similar between the 2 IOL types. The peak IOPs exceeded 60 mm Hg (retinal perfusion pressure). In unsuccessful attempts, the mean and peak IOPs were higher for the conventional IOL, reaching 306.05 mm Hg in 1 eye.
  
  
  CONCLUSIONS
  Monitoring during implantation of both IOL types confirmed that IOP increases during insertion, including during microincision surgery using a wound-assisted technique. Further studies are necessary to evaluate the effect of pressure spikes on the optic nerve during IOL insertion.
authors.affiliation: John A Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. kandon.kamae@hsc.utah.edu
authors.forename: Kandon K
authors.initials: KK
authors.lastname: Kamae
authors.forename: Liliana
authors.initials: L
authors.lastname: Werner
authors.forename: Wellington
authors.initials: W
authors.lastname: Chang
authors.forename: Jonathan T
authors.initials: JT
authors.lastname: Johnson
authors.forename: Nick
authors.initials: N
authors.lastname: Mamalis
mesh_terms: D006801:Humans; D007267:Injections; D007429:Intraocular Pressure / Q000502:physiology*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008866:Microsurgery / Q000379:methods*; D019060:Minimally Invasive Surgical Procedures; D018918:Phacoemulsification / Q000379:methods*