title: Phylogeny of dengue virus type 3 circulating in Colombia between 2001 and 2007.
abstract: Dengue virus type 3 (DENV-3) re-appeared in Colombia in 2001 after 23 years of apparent absence, in the state of Santander in the North-eastern region near to Venezuelan border. In 2002, the virus was isolated in the state of Valle del Cauca in the South-east region near to Ecuadorian/Peruvian border, and in the state of Antioquia in the North-east region near to Panama border. To gain insight into the molecular epidemiology of DENV-3 in Colombia, we sequenced the complete E gene of 21 isolates sampled in the period 2001-2007. Phylogenetic analyses revealed that Colombian strains seem to have been introduced from Venezuela, Ecuador and Peru, but not from Brazil, Argentina, Paraguay or Central America countries. This study also confirms previous report showing that Colombian isolates is closely related to DENV-3 genotype III.
authors.affiliation: Laboratorio de Sistemática & Biogeografía, Escuela de Biología, Universidad Industrial de Santander, Bucaramanga A.A. 678, Colombia.
authors.forename: Christian Julián
authors.initials: CJ
authors.lastname: Villabona-Arenas
authors.forename: Daniel Rafael
authors.initials: DR
authors.lastname: Miranda-Esquivel
authors.forename: Raquel Elvira Ocazionez
authors.initials: RE
authors.lastname: Jimenez
mesh_terms: D003105:Colombia / Q000453:epidemiology; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000821:virology*; D003715:Dengue / Q000145:classification / Q000453:epidemiology / Q000821:virology*; D003716:Dengue Virus / Q000235:genetics*; D019143:Evolution, Molecular; D014644:Genetic Variation / Q000235:genetics; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D010802:Phylogeny; D017422:Sequence Analysis, DNA / Q000379:methods; D014759:Viral Envelope Proteins / Q000235:genetics*
chemical_list: C084188:E protein, Dengue virus type 3; D014759:Viral Envelope Proteins