title: Substance use, childhood sexual abuse, and sexual risk behavior among women in methadone treatment.
abstract: BACKGROUND
  Substance use and a history of childhood sexual abuse (CSA) are risk factors for unprotected sex among women, yet questions remain as to how their combined influence may differentially affect sexual risk.
  
  
  OBJECTIVE
  The current study investigated how complex relationships among drug use and CSA may contribute to unprotected sexual occasions (USO).
  
  
  METHODS
  A Generalized Linear Mixed Model was used to examine the interaction between current cocaine/stimulants and opioid use and CSA on number of USOs in a sample of 214 sexually active women in outpatient methadone maintenance treatment.
  
  
  RESULTS
  For women with CSA, an increase in days of cocaine/stimulant use was associated with a significant increase in USOs. In contrast, an increase in days of opiate use was associated with a significant decrease in USOs. For the group of women who did not report CSA, there was a significant increase in USOs with increased opiate use.
  
  
  CONCLUSIONS
  Findings indicate that CSA is related to unprotected sexual occasions depending on drug type and severity of use.
  
  
  CONCLUSIONS
  Women with CSA using cocaine are at particularly high risk for having unprotected sex and should be specifically targeted for HIV prevention interventions.
authors.affiliation: Department of Psychiatry, Columbia University Medical Center, New York, New York, USA. lc21302columbia.edu
authors.forename: Lisa R
authors.initials: LR
authors.lastname: Cohen
authors.forename: Susan
authors.initials: S
authors.lastname: Tross
authors.forename: Martina
authors.initials: M
authors.lastname: Pavlicova
authors.forename: Mei-Chen
authors.initials: MC
authors.lastname: Hu
authors.forename: Aimee N
authors.initials: AN
authors.lastname: Campbell
authors.forename: Edward V
authors.initials: EV
authors.lastname: Nunes
mesh_terms: D000328:Adult; D002648:Child; D002650:Child Abuse, Sexual / Q000523:psychology*; D005260:Female; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000627:therapeutic use; D018579:Patient Selection; D012309:Risk-Taking; D012720:Severity of Illness Index; D012725:Sexual Behavior / Q000523:psychology*; D019966:Substance-Related Disorders / Q000188:drug therapy / Q000523:psychology*; D011795:Surveys and Questionnaires
chemical_list: D009292:Narcotic Antagonists; D008691:Methadone