Bipolar transurethral resection in saline system versus traditional monopolar resection system in treating large-volume benign prostatic hyperplasia.
OBJECTIVE
We report our prospective clinical result of transurethral resection in saline (TURIS) versus monopolar transurethral resection of the prostate (TURP) system in treating large-volume benign prostatic hyperplasia (BPH).


METHODS
Patients with BPH (volume >50 ml) were enrolled in the study. An intravenous device was used for serum sodium and hemoglobin tests to monitor the alteration. All acute complications were noted. Patients were followed up for at least 6 months.


RESULTS
Forty patients were randomized into two groups. Follow-up data were compared with baseline. The decline in serum sodium postoperatively was smaller in the TURIS group (6.9 +/- 0.7 vs. 14.8 +/- 1.8 mM, p = 0.001). Hemoglobin only dropped by 1.4 g/dl in the TURIS group, whereas it dropped by 2.5 g/dl in the TURP group (p = 0.001). The TURIS system showed a better resection rate (0.64 vs. 0.52 g/min, p = 0.001). Total acute complication rate was 8 of 19 (42%) in the TURP arm and 4 of 21 (19%) in the TURIS arm. The catheter was removed sooner (2.5 vs. 3.4 days) and hospitalization time was less (3.0 vs. 4.2 days) in the TURIS group. The mean improvement in the International Prostate Symptom Score and maximum urinary flow rate at 6 months was comparable in the two groups.


CONCLUSIONS
The TURIS system demonstrated superior safety in treating large-volume BPH and had a similar efficacy to TURP in short term.
Chen
Qi
Q
Department of Urology, Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Zhang
Li
L
Liu
Yu Jun
YJ
Lu
Ji Dong
JD
Wang
Guo Ming
GM
D000368:Aged; D004598:Electrosurgery / Q000009:adverse effects; D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000601:surgery*; D012964:Sodium / Q000097:blood; D012965:Sodium Chloride; D007507:Therapeutic Irrigation; D020728:Transurethral Resection of Prostate / Q000009:adverse effects / Q000379:methods*
D012965:Sodium Chloride; D012964:Sodium