title: Outcomes research in cardiovascular imaging: report of a workshop sponsored by the National Heart, Lung, and Blood Institute.
abstract: In July of 2008, the National Heart, Lung, and Blood Institute convened experts in noninvasive cardiovascular imaging, outcomes research, statistics, and clinical trials to develop recommendations for future randomized controlled trials of the use of imaging in: 1) screening the asymptomatic patient for coronary artery disease; 2) assessment of patients with stable angina; 3) identification of acute coronary syndromes in the emergency room; and 4) assessment of heart failure patients with chronic coronary artery disease with reduced left ventricular ejection fraction. This study highlights several possible trial designs for each clinical situation.
authors.affiliation: Division of Cardiovascular Medicine, Duke University Medical Center, Durham, North Carolina 27715, USA. pamela.douglas@duke.edu
authors.forename: Pamela S
authors.initials: PS
authors.lastname: Douglas
authors.forename: Allen
authors.initials: A
authors.lastname: Taylor
authors.forename: Diane
authors.initials: D
authors.lastname: Bild
authors.forename: Robert
authors.initials: R
authors.lastname: Bonow
authors.forename: Philip
authors.initials: P
authors.lastname: Greenland
authors.forename: Michael
authors.initials: M
authors.lastname: Lauer
authors.forename: Frank
authors.initials: F
authors.lastname: Peacock
authors.forename: James
authors.initials: J
authors.lastname: Udelson
mesh_terms: D000787:Angina Pectoris / Q000175:diagnosis; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D003324:Coronary Artery Disease / Q000175:diagnosis; D003952:Diagnostic Imaging / Q000379:methods; D006333:Heart Failure / Q000175:diagnosis; D006801:Humans; D054555:National Heart, Lung, and Blood Institute (U.S.); D017063:Outcome Assessment, Health Care; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D016032:Randomized Controlled Trials as Topic / Q000592:standards; D012107:Research Design; D014481:United States