title: Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans.
abstract: A MerR family metalloregulatory protein CupR selectively responds to gold stress in Ralstonia metallidurans. A distorted trigonal geometry appears to be used by CupR to achieve the highly sensitive (K(d) approximately 10(-35) M) and selective recognition of gold(I).
authors.affiliation: Department of Chemistry, 929 East 57th Street, The University of Chicago, Chicago, Illinois 60637, USA.
authors.forename: Xing
authors.initials: X
authors.lastname: Jian
authors.forename: Erik C
authors.initials: EC
authors.lastname: Wasinger
authors.forename: Jenny V
authors.initials: JV
authors.lastname: Lockard
authors.forename: Lin X
authors.initials: LX
authors.lastname: Chen
authors.forename: Chuan
authors.initials: C
authors.lastname: He
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D006046:Gold / Q000493:pharmacokinetics*; D011485:Protein Binding; D043367:Ralstonia / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D006046:Gold