Never forget medication as a cause: vaginal ulceration caused by nicorandil.
A patient was referred to our vulvar outpatient clinic because of a vaginal ulceration that persisted for 3 years and that had been unresponsive to any prescribed therapy. After a possible association was found with nicorandil therapy, this medication was stopped. Thereafter, the ulceration fully healed within 6 months.
van de Nieuwenhof
Hedwig P
HP
Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. H.Nieuwenhof@obgyn.umcn.nl
van der Vleuten
Carine J M
CJ
de Hullu
Joanne A
JA
Dukel
Lenno
L
D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D020108:Nicorandil / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced* / Q000473:pathology; D014623:Vaginal Diseases / Q000139:chemically induced* / Q000473:pathology
D000889:Anti-Arrhythmia Agents; D020108:Nicorandil