Neonatal auditory evoked responses are related to perinatal maternal anxiety.
Maternal stress and anxiety during pregnancy are related to negative developmental outcomes for offspring, both physiological and psychological, from the fetal period through early adolescence. This robust relationship is likely to be partly explained by alterations in fetal neurodevelopmental programming, calling for further examination of neurophysiologically-based cognitive markers that may be related to the altered structure-function relationships that contribute to these negative developmental outcomes. The current investigation examined the relationship between perinatal maternal anxiety and neonatal auditory evoked responses (AERs) to mother and stranger voices. Results indicated that neonates of low-anxiety mothers displayed more negative frontal slow wave amplitudes in response to their mother's voice compared to a female stranger's voice, while neonates of high-anxiety mothers showed the opposite pattern. These findings suggest that neonates of perinatally anxious mothers may demonstrate neurophysiologically-based differences in attentional allocation. This could represent one pathway to the negative psychological outcomes seen throughout development in offspring of anxious mothers.
Harvison
Kyle W
KW
University of Louisville, Department of Psychological and Brain Sciences, 317 Life Sciences Building, Louisville, Kentucky 40292, USA. kyle.harvison@allina.com
Molfese
Dennis L
DL
Woodruff-Borden
Janet
J
Weigel
Rebecca A
RA
D000161:Acoustic Stimulation; D000704:Analysis of Variance; D001007:Anxiety; D001307:Auditory Perception / Q000502:physiology; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009034:Mother-Child Relations; D009035:Mothers; D010555:Personality Inventory; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D021641:Recognition, Psychology / Q000502:physiology*; D013067:Speech Perception / Q000502:physiology; D013315:Stress, Psychological; D014831:Voice