title: Evaluation of IFN-gamma serum level in nephropatic type 2 diabetic patients.
abstract: The present study was aimed to examine the serum level of IFN-gamma in type 2 diabetic patients with nephropatic complications. In this experimental study, serum samples were obtained from 100 type 2 diabetic patients suffering from nephropathy and 100 healthy controls. Serum level of IFN-gamma was analyzed by ELISA. Results of this study showed that the mean serum level of IFN-gamma was 16.09 +/- 2.04 and 4.03 +/- 1.00 pg mL(-1) in nephropathic patients and healthy controls, respectively. Statistical analysis of data showed that the difference in the IFN-gamma serum level was significant between nephropathic patients and controls. Due to the elevated level of IFN-gamma in nephropathic patients, it can be possibly concluded that IFN-gamma is involved in nephropathy complication of type 2 diabetes.
authors.affiliation: Department of Laboratory Sciences, Faculty of Medicine, Islamic Azad University, Zahedan Branch, Zahedan, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Nosratabadi
authors.forename: M K
authors.initials: MK
authors.lastname: Arababadi
authors.forename: G
authors.initials: G
authors.lastname: Hassanshahi
authors.forename: N
authors.initials: N
authors.lastname: Yaghini
authors.forename: V
authors.initials: V
authors.lastname: Pooladvand
authors.forename: Ali
authors.initials: A
authors.lastname: Shamsizadeh
authors.forename: E R
authors.initials: ER
authors.lastname: Zarandi
authors.forename: H
authors.initials: H
authors.lastname: Hakimi
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications* / Q000276:immunology; D003928:Diabetic Nephropathies / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D007371:Interferon-gamma