title: An update on acute ischemic stroke therapies.
abstract: Given its short therapeutic time window, successful ischemic stroke therapy requires a multi-disciplinary and streamlined approach. Intravenous recombinant tissue plasminogen activator remains the most efficacious treatment available. New therapies and advances in the understanding comorbidities associated with stroke have reshaped and expanded traditional treatment.
authors.affiliation: Department of Neurological Sciences, Section of Cerebrovascular Disease and Neurologic Critical Care, Rush University Medical Center, 1725 W. Harrison Street, Suite 1121, Chicago, IL 60612, USA.
authors.forename: Aimee Joy
authors.initials: AJ
authors.lastname: Szewka
authors.forename: Shyam
authors.initials: S
authors.lastname: Prabhakaran
mesh_terms: D002985:Clinical Protocols; D004630:Emergencies; D006801:Humans; D009460:Neurologic Examination; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D010959:Tissue Plasminogen Activator