title: Antegrade enemas for defecation disorders: do they improve the colonic motility?
abstract: OBJECTIVE
  The aim of the study was to describe the changes in colonic motility occurring after chronic antegrade enema use in children and young adults.
  
  
  METHODS
  Colonic manometry tracings of patients who had used antegrade enemas for at least 6 months and were being evaluated for possible discontinuation of this treatment were retrospective reviewed.
  
  
  RESULTS
  Seven patients (median age of 12 years, range 3-15 years) met our inclusion criteria. Four patients had idiopathic constipation, 2 had tethered cord, and 1 had Hirschsprung disease. Colonic manometry before the use of antegrade enemas showed dysmotility in 6 (86%) children, mostly in the distal colon. None of the patients underwent colonic resection between the 2 studies. All the patients had colonic manometry repeated between 14 and 46 months after the creation of the cecostomy. All patients with abnormal colonic manometry improved with the use of antegrade enema with a complete normalization of colonic motility in 5 (83%) patients.
  
  
  CONCLUSIONS
  Use of antegrade enema alone, without diversion or resection, may improve colonic motility.
authors.affiliation: Service de Chirurgie Générale Pédiatrique, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada. ann.aspirot.hsj@ssss.gouv.qc.ca
authors.forename: Ann
authors.initials: A
authors.lastname: Aspirot
authors.forename: Sergio
authors.initials: S
authors.lastname: Fernandez
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Lorenzo
authors.forename: Beth
authors.initials: B
authors.lastname: Skaggs
authors.forename: Hayat
authors.initials: H
authors.lastname: Mousa
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003106:Colon / Q000503:physiopathology*; D003248:Constipation / Q000503:physiopathology / Q000628:therapy*; D004733:Enema / Q000379:methods*; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D006627:Hirschsprung Disease / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008365:Manometry; D009436:Neural Tube Defects / Q000503:physiopathology; D016896:Treatment Outcome