title: NMR assignment of the C-terminal actin-binding domain of talin.
abstract: Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin beta-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.
authors.affiliation: Department of Biochemistry, University of Leicester, Lancaster Road, Leicester LE19HN, UK.
authors.forename: Benjamin T
authors.initials: BT
authors.lastname: Goult
authors.forename: Alexandre R
authors.initials: AR
authors.lastname: Gingras
authors.forename: Neil
authors.initials: N
authors.lastname: Bate
authors.forename: Gordon C K
authors.initials: GC
authors.lastname: Roberts
authors.forename: David R
authors.initials: DR
authors.lastname: Critchley
authors.forename: Igor L
authors.initials: IL
authors.lastname: Barsukov
mesh_terms: D000199:Actins / Q000737:chemistry*; D000595:Amino Acid Sequence; D001665:Binding Sites; D002247:Carbon Isotopes / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D011485:Protein Binding; D011522:Protons; D016608:Talin / Q000737:chemistry*
chemical_list: D000199:Actins; D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D011522:Protons; D016608:Talin