title: A case of a newly developed yellow neointima at stent implanted site 1 year after sirolimus-eluting stent placement: angioscopic findings.
abstract: Coronary angioscopy is a useful tool for understanding plaque characteristics through the plaque color and surface thrombus formation. We experienced an interesting case of a newly developed yellow neointima 400 days after a sirolimus-eluting stent implantation. A 72-year-old woman suffering from angina pectoris was admitted to our hospital. Coronary angiography revealed severe stenosis at the proximal left descending artery and she was implanted with a sirolimus-eluting stent. Coronary angioscopic observation immediately after stent implantation revealed the presence of yellow plaque only at the most severe stenosis lesion in the stent placement site. We performed a coronary angiography 400 days after the sirolimus-eluting stent implantation and did not find an in-stent restenosis. An intravascular ultrasound indicated minimum neointimal formation. By coronary angioscopy, we could clearly observe that the neointima had covered the surface of the stent struts; the stent struts were barely visible under the neointima. Surprisingly, neointima formed in response to the sirolimus-eluting stent was entirely yellow. Precise mechanisms of producing yellow neointima was unknown, we may observe a pathologic neointima induced by sirolimus-eluting stent.
authors.affiliation: Department of Cardiology, Ehime Prefectural Imabari Hospital, 4-5-5 Ishii-cho, Imabari, Ehime 794-0006, Japan. i-kawakami-h@epnh.pref.ehime.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Kawakami
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuoka
authors.forename: Akira
authors.initials: A
authors.lastname: Oshita
authors.forename: Tamami
authors.initials: T
authors.lastname: Kono
authors.forename: Susumu
authors.initials: S
authors.lastname: Shigemi
mesh_terms: D000368:Aged; D017546:Angioscopy; D003331:Coronary Vessels / Q000473:pathology*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D058426:Neointima / Q000473:pathology*; D020123:Sirolimus
chemical_list: D020123:Sirolimus