title: HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture.
abstract: HPLC-SPE-NMR analysis of a crude extract of fermentation broth of cultured PESTALOTIOPSIS VIRGATULA isolate TC-320 from TERMINALIA CHEBULA Retz. (Combretaceae) disclosed the presence of a simple but unprecedented low-molecular-weight metabolite, 9-hydroxybenzo[ C]oxepin-3[1 H]-one, subsequently isolated by a targeted purification procedure.
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Julie R
authors.initials: JR
authors.lastname: Kesting
authors.forename: Dan
authors.initials: D
authors.lastname: Staerk
authors.forename: Mysore V
authors.initials: MV
authors.lastname: Tejesvi
authors.forename: Kukkundoor R
authors.initials: KR
authors.lastname: Kini
authors.forename: Harishchandra S
authors.initials: HS
authors.lastname: Prakash
authors.forename: Jerzy W
authors.initials: JW
authors.lastname: Jaroszewski
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D001584:Benzoxepins / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D001584:Benzoxepins