NMR assignment of human chemerin, a novel chemoattractant.
Chemerin is a potent chemoattractant for cells expressing the GPCR CMKLR1, and is thought to play important roles in cell migration and recruitment to sites of tissue damage and inflammation. Here we report the NMR assignments of the 15.6 kDa active form of uniformly (15)N, (13)C labeled chemerin.
Allen
Samantha J
SJ
University of California, San Diego, La Jolla, 92093-0684, USA. samallen@ucsd.edu
Zabel
Brian A
BA
Kirkpatrick
John
J
Butcher
Eugene C
EC
Nietlispach
Daniel
D
Handel
Tracy M
TM
D000595:Amino Acid Sequence; D018925:Chemokines / Q000737:chemistry*; D002630:Chemotactic Factors / Q000737:chemistry*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D017434:Protein Structure, Tertiary
D018925:Chemokines; D002630:Chemotactic Factors; D036341:Intercellular Signaling Peptides and Proteins; C478630:RARRES2 protein, human