title: A prospective study of symptom distress and return to baseline function after open versus laparoscopic radical prostatectomy.
abstract: OBJECTIVE
  We assessed and compared outcomes following open and laparoscopic radical prostatectomy.
  
  
  METHODS
  Patients who were scheduled to undergo open or laparoscopic radical prostatectomy were enrolled in the study and followed prospectively. Before surgery the patients were administered a multi-item validated questionnaire, and were followed by telephone and with mail questionnaires periodically for 12 months. Complications were recorded from chart review and compared. Symptom distress and return to baseline for various parameters were compared between the 2 groups.
  
  
  RESULTS
  Of the patients 102 who underwent open prostatectomy and 104 treated with laparoscopic prostatectomy were enrolled in the study. At 1 year 90% in the open and 91% in the laparoscopic group returned the questionnaire. Symptom distress between the 2 groups did not differ at any time during followup. There was no significant difference in return to baseline at 1 year for continence, erectile function or physical function. Of the patients 95% had a return to baseline physical function, approximately 90% do not wear a pad and approximately 50% returned to baseline erectile function with or without phosphodiesterase type 5 inhibitors at 1 year. Although complications were few there was a significant difference in the number for laparoscopic vs open prostatectomy with a slightly higher rate of hematuria and lymphocele formation in the laparoscopic group. Cancer control at 1 year was excellent in both groups.
  
  
  CONCLUSIONS
  Radical prostatectomy is an effective form of therapy for patients with clinically localized cancer of the prostate. The open and laparoscopic techniques have similar functional outcomes, and these data provide patients a realistic view of what to expect following these 2 methods of radical prostatectomy.
authors.affiliation: Departments of Urology and Medicine, Massachusetts General Hospital and the Harvard Medical School, Boston, Massachusetts 02114, USA. wmcdougal@partners.org
authors.forename: Douglas M
authors.initials: DM
authors.lastname: Dahl
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Barry
authors.forename: Francis J
authors.initials: FJ
authors.lastname: McGovern
authors.forename: Yuchaio
authors.initials: Y
authors.lastname: Chang
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Walker-Corkery
authors.forename: W Scott
authors.initials: WS
authors.lastname: McDougal
mesh_terms: D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000601:surgery*; D020127:Recovery of Function; D011795:Surveys and Questionnaires