Baby got brain: Fgf10 sets rostral cortical size.
Brain growth occurs throughout embryogenesis and early postnatal life, but its foundation is laid in the primitive neuroepithelium. In this issue of Neuron, Sahara and O'Leary identify Fgf10 as a key regulator of the neuroepithelial to radial glial transition and subsequently of size of the rostral forebrain.
Phoenix
Timothy N
TN
New York Neural Stem Cell Institute, Rensselaer, NY 12144, USA.
Temple
Sally
S
D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology* / Q000502:physiology*; D051526:Fibroblast Growth Factor 10 / Q000502:physiology*; D006801:Humans; D007223:Infant; D009457:Neuroglia / Q000502:physiology; D009474:Neurons / Q000502:physiology
C496463:FGF10 protein, human; D051526:Fibroblast Growth Factor 10