Simple lab-on-chip approach with time-based detection.
A simple lab-on-chip approach with time-based detection is proposed. A platform is made from a piece of acrylic differently shaped channels for introducing sample and reagent(s) using flow manipulation. Time-based changes involving migration of the reaction zone are monitored. The changes can be visually monitored by using a stop-watch with naked eyes observation. Some applications for the determination of ascorbic acid, acetic acid and iron in real samples with different chemistries were demonstrated.
Grudpan
K
K
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand. kate@chiangmai.ac.th
Lapanantnoppakhun
S
S
Hartwell
S Kradtap
SK
Watla-iad
K
K
Wongwilai
W
W
Siriangkhawut
W
W
Jangbai
W
W
Kumutanat
W
W
Nuntaboon
P
P
Tontrong
S
S
D019342:Acetic Acid / Q000032:analysis / Q000737:chemistry; D001205:Ascorbic Acid / Q000032:analysis / Q000737:chemistry; D003116:Color; D004396:Coloring Agents / Q000737:chemistry; D007501:Iron / Q000032:analysis; D046208:Microchip Analytical Procedures / Q000191:economics / Q000379:methods*; D010969:Plastics / Q000737:chemistry; D013607:Tablets; D013997:Time Factors
D004396:Coloring Agents; D010969:Plastics; D013607:Tablets; D007501:Iron; D001205:Ascorbic Acid; D019342:Acetic Acid