title: HeartMate II implantation in patients with heparin-induced thrombocytopenia type II.
abstract: Diverse anticoagulation protocols are used in patients after implantation of ventricular assist devices. No consensus exists, especially in patients with heparin-induced thrombocytopenia type II. In a patient with heparin-induced thrombocytopenia type II, we implanted a left ventricular assist device (HeartMate XVE; Thoratec, Pleasanton, CA). Thirteen months later the device had to be replaced due to mechanical failure with a HeartMate II left ventricular assist device. We report on our successful protocol of perioperative anticoagulation management using heparin and iloprost during surgery and argatroban thereafter.
authors.affiliation: Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Anna Lassia
authors.initials: AL
authors.lastname: Meyer
authors.forename: Doris
authors.initials: D
authors.lastname: Malehsa
authors.forename: Christian
authors.initials: C
authors.lastname: Kuehn
authors.forename: Christoph
authors.initials: C
authors.lastname: Bara
authors.forename: Clemens
authors.initials: C
authors.lastname: Gras
authors.forename: Carsten
authors.initials: C
authors.lastname: Hafer
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.forename: Martin
authors.initials: M
authors.lastname: Strüber
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects; D001120:Arginine / Q000031:analogs & derivatives; D002315:Cardiopulmonary Bypass; D004359:Drug Therapy, Combination; D006353:Heart-Assist Devices; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D016285:Iloprost / Q000008:administration & dosage; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010875:Pipecolic Acids / Q000008:administration & dosage; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D013449:Sulfonamides; D013921:Thrombocytopenia / Q000139:chemically induced; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D010875:Pipecolic Acids; D010975:Platelet Aggregation Inhibitors; D013449:Sulfonamides; D014859:Warfarin; D006493:Heparin; D001120:Arginine; C031942:argatroban; D016285:Iloprost