Rhenium-catalyzed regioselective alkylation of phenols.
Treatment of phenol derivatives with terminal alkenes in the presence of a catalytic amount of a rhenium complex, Re(2)(CO)(10), gave monoalkylated phenol derivatives in good to excellent yields. This reaction proceeds at the ortho- or para-position of phenols regioselectively.
Kuninobu
Yoichiro
Y
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Kita-ku, Okayama 700-8530, Japan. kuninobu@cc.okayama-u.ac.jp
Matsuki
Takashi
T
Takai
Kazuhiko
K
D000478:Alkylation; D002384:Catalysis; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry*; D012211:Rhenium / Q000737:chemistry*; D013237:Stereoisomerism
D010636:Phenols; D012211:Rhenium