Physical activity and diet behaviour in colorectal cancer patients receiving chemotherapy: associations with quality of life.
BACKGROUND
The relationship between colorectal cancer (CRC) risk and physical activity and dietary habits has been well-established, but less is known about the relationship between these behaviours and quality of life (QOL) post-diagnosis. Moreover, it is unknown whether this relationship is consistent across cancer stage or treatment setting. Thus, the purpose of this study was to assess current diet and physical activity behaviour in CRC survivors receiving systemic chemotherapy, and to examine potential associations between these behaviours and quality of life. A secondary purpose was to examine the association between social support, diet, and physical activity behaviour in this population.


METHODS
Using a cross-sectional survey, 67 CRC survivors currently receiving chemotherapy in Calgary, Alberta completed the survey package. Measures included demographic and medical data, physical activity levels, diet behaviour, QOL, and social support.


RESULTS
In a largely metastatic sample (63%), approximately half were meeting national dietary guidelines (58%), less were meeting national physical activity guidelines (26%), and a small number were meeting both (17%). However, only 12.3% (n = 8) reported completely sedentary behaviour, and 7 of these 8 participants were receiving metastatic treatment. Neither behaviour was significantly associated with QOL or perceived social support. Furthermore, there were no significant QOL differences between those treated with palliative intent or adjuvant therapy. Important group differences emerged between those meeting and not meeting the guidelines, and associations between QOL, age, BMI, and provisions of social support.


CONCLUSIONS
These findings provide insight into lifestyle behaviours of CRC survivors currently receiving systemic chemotherapy, and the differences in perceived QOL as affected by severity of disease and treatment setting. Prospective studies in a larger sample of CRC survivors on chemotherapy are needed to confirm lifestyle behaviour patterns and identify factors related to QOL that are unique to this population, especially during metastatic treatment.
Stephenson
Lynette E
LE
Faculty of Kinesiology, University of Calgary, 2500 University Dr. NW, Calgary Alberta, T2N 1N4, Canada. lstephenson@kin.ucalgary.ca
Bebb
D Gwyn
DG
Reimer
Raylene A
RA
Culos-Reed
S Nicole
SN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000416:Alberta; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology*; D003430:Cross-Sectional Studies; D004032:Diet / Q000523:psychology*; D004358:Drug Therapy; D005247:Feeding Behavior / Q000502:physiology / Q000523:psychology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D012944:Social Support