title: Extensively drug-resistant tuberculosis: a new face to an old pathogen.
abstract: The presence and consequences of resistance to drugs used for the treatment of tuberculosis have long been neglected. The recent detection and recognition of widespread multiple-drug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis have raised interest and concern among clinicians and public health authorities globally. In this article, we describe the current global status of drug-resistant tuberculosis. We discuss the development of resistance, current management, and strategies for control.
authors.affiliation: Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut 06510-8002, USA. sheela.shenoi@yale.edu
authors.forename: Sheela
authors.initials: S
authors.lastname: Shenoi
authors.forename: Gerald
authors.initials: G
authors.lastname: Friedland
mesh_terms: D054908:Extensively Drug-Resistant Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D012307:Risk Factors