title: [Fibrolamellar liver carcinoma: report of two cases and review of the literature].
abstract: Fibrolamellar hepatocellular carcinoma (FLC) is a rare histologic variant of hepatocellular carcinoma that appears most commonly in teenagers and young adults. The diagnosis is often made incidentally and surgical resection is the only curative treatment. Here we report two cases of incidental FLC involving a 19 year-old male, initially diagnosed with screening abdominal ultrasound, and a 14 year-old female that presented with abdominal pain. Diagnostic workup consisted of abdominal PET/CT and MR1 Imaging studies and tissue diagnosis was confirmed with percutaneous liver biopsy. Both patients were treated with radical liver resection/tumor excision. However, tumor recurrence was observed in both during short-term follow-up. The male patient was treated successfully with surgical treatment however the female patient succumbed top regression of disease.
authors.affiliation: Instituto Oncológico Fundación Arturo López Pérez, Santiago,Chile.
authors.forename: Jean M
authors.initials: JM
authors.lastname: Butte
authors.forename: Enrique
authors.initials: E
authors.lastname: Waugh
authors.forename: Manuel
authors.initials: M
authors.lastname: Meneses
authors.forename: Rossana
authors.initials: R
authors.lastname: Pruzzo
authors.forename: Cristian
authors.initials: C
authors.lastname: Carvallo
authors.forename: Francisca
authors.initials: F
authors.lastname: Redondo
authors.forename: Claudio
authors.initials: C
authors.lastname: Suárez
authors.forename: Hugo
authors.initials: H
authors.lastname: Parada
authors.forename: Horacio
authors.initials: H
authors.lastname: Amaral
authors.forename: Hernán
authors.initials: H
authors.lastname: de La Fuente
mesh_terms: D000293:Adolescent; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000473:pathology / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009364:Neoplasm Recurrence, Local; D014057:Tomography, X-Ray Computed; D055815:Young Adult