Community effect of Haemophilus influenzae type b vaccination in India.
We assessed the effect of distribution of Haemophilus influenzae type b (Hib) vaccine in the private health care sector on Hib meningitis admissions at a referral hospital in India. The annual mean number of Hib cases was 10.7 before Hib vaccine introduction, falling to 3.8 cases following introduction (P < 0.0001). By contrast, the mean of annual numbers of pneumococcal cases were 3.0 and 4.6, (P = 0.55). Even at relatively low coverage through private sector distribution, Hib vaccine has significant community impact on Hib disease.
Verghese
Valsan Philip
VP
Department of Child Health, Christian Medical College, Vellore, India. valsan@cmcvellore.ac.in
Friberg
Ingrid K
IK
Cherian
Thomas
T
Raghupathy
Palany
P
Balaji
V
V
Lalitha
M K
MK
Thomas
Kurien
K
John
T Jacob
TJ
Steinhoff
Mark C
MC
D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000276:immunology; D019741:Haemophilus influenzae type b / Q000276:immunology*; D006801:Humans; D007194:India / Q000453:epidemiology; D032541:Mass Vaccination; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000276:immunology* / Q000517:prevention & control; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D016012:Poisson Distribution; D011159:Population Surveillance; D011446:Prospective Studies; D012044:Regression Analysis; D013296:Streptococcus pneumoniae / Q000276:immunology
D018073:Haemophilus Vaccines