[Methicillin-resistant Staphylococcus aureus at a general hospital: epidemiological overview between 2000-2007].
BACKGROUND
The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients is a significant problem due to its associated morbidity and mortality. It is important to know the recent MRSA epidemiology at a General Hospital.


OBJECTIVE
To determine the MRSA epidemiology at a Mexican general hospital from 2000 to 2007, in order to know if there is a significant trend in its proportion.


METHODS
Prevalence survey. The resistance to oxacillin was identified by the Kirby-Bauer's method. The specimens were classified by type and year of isolation. Trend statistics were used for analysis.


RESULTS
S. aureus was identified in 1,008 samples, being 301 resistant to oxacillin (30%, 95% Confidence Interval [CI], 25 to 35%). The proportion of MRSA went from 37% (95% CI, 29 to 44%) to 49% (95% CI, 40 to 58%) in the period of study (chi2 for trends = 6.676, p < 0.01). Specimens with the highest proportion of MRSA were blood and sterile liquids with 32% (95% CI, 26 to 39%), secretions with 29% (95% CI, 24 to 33%), and catheters with 21% (95% CI, 16 to 26%).


CONCLUSIONS
The proportion of MRSA has increased significantly. This leads to higher costs and morbi-mortality for the hospitalized patients. We require stricter policies to prevent transmission and to control the use of antibiotics.
Alvarez
José Antonio
JA
Facultad de Medicina de León, Universidad de Guanajuato. micros_iesus@yahoo.com
Ramírez
América Jazmín
AJ
Mojica-Larrea
Miriam
M
Huerta
Jessica del Rocío
Jdel R
Guerrero
Jennifer Dayane
JD
Rolón
Ana Lilia
AL
Medina
Humberto
H
Muñoz
Juan Manuel
JM
Mosqueda
Juan Luis
JL
Macías
Alejandro Ernesto
AE
Sifuentes-Osornio
José
J
D003428:Cross Infection / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D006769:Hospitals, General / Q000706:statistics & numerical data*; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D009017:Morbidity / Q000639:trends; D010068:Oxacillin / Q000494:pharmacology; D015995:Prevalence; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology
D010068:Oxacillin