title: Mitral valve replacement with the pulmonary autograft: midterm results.
abstract: OBJECTIVE
  We performed mitral valve replacement with a pulmonary autograft using the technique described by us earlier and present the results.
  
  
  METHODS
  Between August 2000 and July 2007, 19 patients (16 male patients; age, 30-58 years) with isolated calcific mitral stenosis (n = 16) or mixed mitral stenosis and regurgitation (n = 3) underwent mitral valve replacement with a pulmonary autograft. Sixteen patients were in New York Heart Association class III and 3 were in New York Heart Association class IV preoperatively. Eight patients were in atrial fibrillation. The autograft implantation was achieved by using a scalloped stent of polytetrafluoroethylene felt for external support of the autograft. No anticoagulants were prescribed.
  
  
  RESULTS
  There were 3 early deaths, one each caused by ventricular dysfunction, ventricular arrhythmias, and autograft dehiscence requiring early reoperation. Follow-up of survivors ranged from 34 to 99 months (mean, 71.9 +/- 18.2 months; median, 75 months). The mean valve area was 2.96 +/- 0.9 cm(2) (range, 2.2-4.3 cm(2)). Fourteen survivors are in New York Heart Association class I, and 2 are in NYHA class II; 4 continue to be in atrial fibrillation. Follow-up echocardiograms (n = 16), magnetic resonance imaging (n = 6), and cardiac catheterization (n = 4) have demonstrated no significant autograft and pulmonary homograft dysfunction. There were no late deaths or reoperations or thromboembolic complications.
  
  
  CONCLUSIONS
  Mitral valve replacement with a pulmonary autograft, a complex operation, can be performed in selected patients with acceptable results. The use of our technique of autograft implantation offers several advantages and avoids exposure of the scaffold to the bloodstream.
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India. asampath_kumar@hotmail.com
authors.forename: Arkalgud Sampath
authors.initials: AS
authors.lastname: Kumar
authors.forename: Sachin
authors.initials: S
authors.lastname: Talwar
authors.forename: Anubhav
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000601:surgery; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D018572:Disease-Free Survival; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D011664:Pulmonary Valve / Q000637:transplantation*; D012086:Reoperation; D012214:Rheumatic Heart Disease / Q000150:complications; D014182:Transplantation, Autologous; D014463:Ultrasonography