title: Marginal mandibulectomy in oral cancer surgery: a 13-year experience.
abstract: The management of the mandible when dealing with oral cavity cancer is still controversial. In this article, we present our experience with marginal mandibulectomy over a 13-year period. We retrospectively evaluated 56 patients who underwent marginal mandibulectomy between 1990 and 2002. Mean age at surgery was 60.3 + or - 9.5 SD years. Neither intraoperative nor perioperative deaths were observed. Infiltration of the resected bone was detected in only one patient (1.8%). Fracture of the mandible was a complication in only one patient (1.8%). Eight patients (14.3%) presented a local and/or regional recurrence. Distant metastases were diagnosed in two patients (3.6%). The 5-year overall and disease-specific survival rates were 60.7 and 77.3%, respectively. Marginal mandibulectomy allows to conduct the resection in a safe tissue or to excise tumors of the floor of the mouth with a limited involvement of the alveolar periosteum. Whenever the tumor is close to the mandible or when it adheres to the alveolar periosteum, marginal mandibulectomy offers the possibility to perform an oncologically sound procedure.
authors.affiliation: 1st Unit of Otorhinolaryngology, Department of Neuroscience, University of Pisa, Via Savi, 10, 56126 Pisa, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Muscatello
authors.forename: Riccardo
authors.initials: R
authors.lastname: Lenzi
authors.forename: Raul
authors.initials: R
authors.lastname: Pellini
authors.forename: Marco
authors.initials: M
authors.lastname: Giudice
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Spriano
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008310:Malocclusion / Q000453:epidemiology / Q000209:etiology; D008334:Mandible / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery*; D019647:Oral Surgical Procedures / Q000379:methods*; D010146:Pain / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D011183:Postoperative Complications; D013705:Temporomandibular Joint Disorders / Q000453:epidemiology / Q000209:etiology; D016896:Treatment Outcome