title: Simultaneous ST-segment elevation in inferior and precordial leads following ingestion of a lethal dose of desipramine: a novel Brugada-like EKG pattern.
abstract: The typical Brugada electrocardiographic (EKG) pattern includes ST-segment elevation in the right precordial leads (V1-V3) associated with right bundle branch block (rSR') like morphology. Recently, a Brugada-like EKG pattern with ST-segment elevation in inferior leads called the "Brugada variant" has been reported. We report a case of simultaneous typical and variant Brugada EKG patterns with ST-segment elevation in the inferior as well as the precordial leads following ingestion of a lethal dose of desipramine.
authors.affiliation: The University of Toledo Medical Center, 3000 Arlington ave, Toledo, OH, 43614, USA.
authors.forename: Mujeeb
authors.initials: M
authors.lastname: Sheikh
authors.forename: Khalil
authors.initials: K
authors.lastname: Kanjwal
authors.forename: Rahil
authors.initials: R
authors.lastname: Kasmani
authors.forename: Surendra
authors.initials: S
authors.lastname: Chutani
authors.forename: James D
authors.initials: JD
authors.lastname: Maloney
mesh_terms: D053840:Brugada Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D002037:Bundle-Branch Block / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D003131:Combined Modality Therapy; D003891:Desipramine / Q000506:poisoning*; D018450:Disease Progression; D004562:Electrocardiography; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D013406:Suicide, Attempted
chemical_list: D003891:Desipramine