[ACTH-dependent Cushing syndrome, a diagnostic challenge].
ACTH dependent Cushing syndrome accounts for approximately 80% of all Cushing syndrome. Distinguishing the pituitary origin from ectopic one is still a diagnosis problem in some cases, especially in bronchial carcinoids, because approximately 50% show cortisol suppresion after dexametasone and may be small and, therefore, difficult to detect in chest radiography. We present a case of a patient with ACTH dependent Cushing syndrome of difficult localization with usual diagnosis tests.
Fuentes Tudanca
Sergio
S
Sección de Endocrinología. Hospital Severo Ochoa. Leganés. Madrid. España. drsfuentes@gmail.com
Ortiz de Urbina
Purificación Martínez de Icaya
PM
De Dios
Luis Muñoz
LM
Gallego Rodríguez
Sergio
S
Pérez Pelayo
Míriam
M
Del Olmo García
Dolores
D
D000182:ACTH Syndrome, Ectopic / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001984:Bronchial Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D001999:Bronchoscopy; D002276:Carcinoid Tumor / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D003480:Cushing Syndrome / Q000209:etiology*; D003951:Diagnostic Errors; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D047748:Pituitary ACTH Hypersecretion / Q000175:diagnosis*; D011013:Pneumonectomy; D011859:Radiography; D019564:Unnecessary Procedures
D014408:Biomarkers, Tumor; D000324:Adrenocorticotropic Hormone