[Mucosal healing in Crohn disease].
Crohn disease treatment is a considerable challenge for a medical doctor. Gaining clinical remission is not enough. The important factor taken into account in treatment is gaining clinical remission and complete mucosal healing. Treatment useful in mucosal healing consists of immunosupresants as azathioprine, 6-markaptopurin, methotrexate and biological treatment. Important factors influencing mucosal healing is choice of medical treatment and its proper timing. More aggressive treatment in top-down scheme appears to be more successful in this aspekt than classical treatment with use of steroids. This data requires verification with more clinical trials.
Jałocha
Lukasz
L
Military Institute of Health Services in Warsaw, Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense. ljalocha@yahoo.com
Wojtuń
Stanisław
S
Dyrla
Przemysław
P
Blaszak
Antoni
A
Wojtkowiak
Marek
M
Zysko
Bogusław
B
Gil
Jerzy
J
D003424:Crohn Disease / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007413:Intestinal Mucosa / Q000503:physiopathology*; D012038:Regeneration / Q000187:drug effects; D012074:Remission Induction; D016896:Treatment Outcome
D007166:Immunosuppressive Agents