title: [Splenic infarction at high altitude, Huaraz-Peru (3,100 masl)].
abstract: We report three cases of splenic infarction in healthy men for the first time that amounted to high altitudes, observed in the hospital "Victor Ramos Guardia" Huaraz (3100 m). Case 1 (1995) of 55 years, born in Cuba, from Lima, caucasian suddenly presented acute abdominal pain in epigastrium, distension, nausea and vomiting, was laparotomized for acute abdomen and surgical pathology revealed thrombosis with splenic infarction splenic artery and vein. During follow-up in Lima, hemoglobin electrophoresis showed that it was heterozygous carrier of the sickle trait (Hb A: 57% Hb S: 38.5%). Case 2 (1998) of 23 years, born in Cuba, from Lima, Black said acute abdominal pain in left hypochondrium, shortness of breath and chest pain, clinical examination and radiography of the abdomen showed the spleen volume increased. Case 3 (2006) of 17 years, natural and from Lima, mestizo, who came on tour promotion, acute abdominal pain referred onset in the epigastrium and left hypochondrium, headache, increase heat, nausea and vomiting, pharyngitis was found acute and painful, and spleen increased in size by clinical and x-ray of abdomen simple stand. None had no history of hemoglobinopathy and anemia. In general, medical management was supportive and cases 2 and 3 are recommended hemoglobin electrophoresis. We conclude that we must think of splenic infarction associated with height in any healthy person who is first at high altitude (> 3000m) and having a sudden acute abdominal pain in epigastrium and / or left hypochondrium, pain and palpable spleen and radiological study compatible with image. In this case is indicated by hemoglobin electrophoresis to determine whether there is an individual heterozygous carrier of the sickle trait.
  
  
  BACKGROUND
  splenic infarction, high altitude, sickle trait, Huaraz.
authors.affiliation: Jefe del Departamento de Emergencia del Hospital VIctor RAmos Guardia de Huaraz, Universidad Nacional de Ancash, Perú.
authors.forename: Douglas
authors.initials: D
authors.lastname: López de Guimaraes
authors.forename: Julio
authors.initials: J
authors.lastname: Menacho López
authors.forename: Jovita
authors.initials: J
authors.lastname: Villanueva Palacios
authors.forename: Vitaliano
authors.initials: V
authors.lastname: Mosquera Vásquez
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000531:Altitude; D001064:Appendicitis / Q000175:diagnosis; D001272:Atmosphere; D003462:Cuba / Q000208:ethnology; D003937:Diagnosis, Differential; D004198:Disease Susceptibility; D004630:Emergencies; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D010568:Peru; D011859:Radiography; D012805:Sickle Cell Trait / Q000150:complications* / Q000175:diagnosis; D013156:Splenectomy; D013159:Splenic Infarction / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D055815:Young Adult