Carbolithiation of conjugated enynes with aryllithiums in microflow system and applications to synthesis of allenylsilanes.
Carbolithiation of conjugated enynes with aryllithiums generated by Br-Li exchange reaction followed by reaction of the allenyllithium compounds with chlorosilanes was carried out in a microflow system to obtain various allenylsilanes in good yields.
Tomida
Yutaka
Y
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.
Nagaki
Aiichiro
A
Yoshida
Jun-ichi
J