Trends in the European HIV/AIDS epidemic: a perspective from Italy.
The HIV/AIDS epidemic represents one of the major public-health challenges in present days. Despite the relevant improvement in the prognosis of HIV disease following the introduction of highly active antiretroviral therapy (HAART), numerous new challenges are progressively emerging as patient characteristics evolve. In this article, we give an insight into more actual topics in the HIV/AIDS epidemic in Italy and Europe, including recent epidemiological trends, emerging drug resistance and non-B-subtype circulation, the lights and shadows of HAART and the potential of HARRT to reduce sexual transmission of HIV.
Madeddu
Giordano
G
Department of Infectious Diseases, University of Sassari, Via De Nicola 1, 07100 Sassari, Italy. giordano.madeddu@uniss.it
Rezza
Giovanni
G
Mura
Maria Stella
MS
D000293:Adolescent; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D004196:Disease Outbreaks; D024882:Drug Resistance, Viral; D005060:Europe / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology; D015497:HIV-1 / Q000145:classification / Q000187:drug effects* / Q000235:genetics; D015498:HIV-2 / Q000145:classification / Q000187:drug effects* / Q000235:genetics; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012309:Risk-Taking; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D055815:Young Adult