A case of extensive Aplasia Cutis Congenita with underlying skull defect and central nervous system malformation: discussion of large skin defects, complications, treatment and outcome.
Aplasia Cutis Congenita (ACC) is a rare condition characterized by the absence of a portion of skin at birth. Skin defects are usually small (0.5 to 3 cm) and located on the scalp. Although there can be other physical or genetic abnormalities, ACC is most often a benign isolated condition. Rarely is an underlying bony defect present, and this association increases the rate of complications. We report a case of a newborn male with ACC of the entire crown and vertex scalp, non-ossified parietal skull and dysplastic corpus callosum. The patient's skull and skin defects were treated non-surgically, and he recovered well.
Burkhead
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University of North Carolina School of Medicine, Chapel Hill, NC 27599-9535, USA. anna_burkhead@med.unc.edu
Poindexter
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Morrell
D S
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D061085:Agenesis of Corpus Callosum; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D003337:Corpus Callosum / Q000502:physiology; D004476:Ectodermal Dysplasia / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010012:Osteogenesis; D012837:Silver Sulfadiazine / Q000627:therapeutic use; D012886:Skull / Q000002:abnormalities* / Q000502:physiology
D000891:Anti-Infective Agents, Local; D012837:Silver Sulfadiazine