title: Ovarian hyperstimulation secondary to ectopic secretion of follicle-stimulating hormone. Literature review prompted by a case.
abstract: OBJECTIVE
  To present an exceptional clinical case of functional follicle-stimulating gonadotropin secretion by a thorax neuroendocrine carcinoid tumor.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Department of Obstetrics and Gynecology, Cruces University Hospital, Vizcaya, Spain.
  
  
  METHODS
  A 26-year-old woman with ovarian hyperstimulation.
  
  
  METHODS
  Diagnosis algorithm.
  
  
  METHODS
  Successful management of ovarian hyperstimulation.
  
  
  RESULTS
  A 26-year-old woman seen with abdominal pain and swelling had bilateral multicystic ovaries. The diagnosis algorithm revealed the presence of ovarian hyperstimulation but with no due etiology. On the basis of the persistence of high levels of FSH a computed tomographic scan was taken looking for an FSH-producing neuroendocrine tumor.
  
  
  CONCLUSIONS
  In idiopathic ovarian hyperstimulation secondary to supraphysiologic secretion of FSH, the presence of an FSH-producing neuroendocrine tumor should be considered. As far as we know, there are no similar cases with a confirmed diagnosis published in the literature.
authors.affiliation: Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain; School of Medicine, Universidad del País Vasco, Vizcaya, Spain. Electronic address: jburgoss@sego.es.
authors.forename: Jorge
authors.initials: J
authors.lastname: Burgos
authors.affiliation: Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: Cobos
authors.affiliation: School of Medicine, Universidad del País Vasco, Vizcaya, Spain; Department of Anatomopathology, Hospital de Cruces, Vizcaya, Spain.
authors.forename: Nerea
authors.initials: N
authors.lastname: Vidaurrazaga
authors.affiliation: Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
authors.forename: Begoña
authors.initials: B
authors.lastname: Prieto
authors.affiliation: School of Medicine, Universidad del País Vasco, Vizcaya, Spain; Endoscopy Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
authors.forename: Iratxe
authors.initials: I
authors.lastname: Ocerin
authors.affiliation: Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain; School of Medicine, Universidad del País Vasco, Vizcaya, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Matorras
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006801:Humans; D016471:Ovarian Hyperstimulation Syndrome / Q000175:diagnosis* / Q000209:etiology*; D013899:Thoracic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D005640:Follicle Stimulating Hormone