title: Biofilm development by clinical strains of non-pigmented rapidly growing mycobacteria.
abstract: The relationship between clinical significance of non-pigmented, rapidly growing mycobacteria (NPRGM), in vitro biofilm development and sliding motility was evaluated in this study. One hundred and sixty-eight clinical strains of NPRGM were included. Forty-one of these were clinically significant isolates. Biofilm was formed by 123 strains. Seventy-six biofilm-positive and 25 biofilm-negative strains showed sliding motility. There was a relationship between clinical significance and biofilm development (p <0.000,001), sliding motility (p 0.0037) and species (p <0.000,001). No relationship was found between motility and biofilm development. The ability to develop biofilm is a characteristic that can have importance in the development of infections caused by NPRGM.
authors.affiliation: Department of Clinical Microbiology, Fundación Jiménez Díaz-UTE, Madrid, Spain.
authors.forename: N Z
authors.initials: NZ
authors.lastname: Martín-de-Hijas
authors.forename: D
authors.initials: D
authors.lastname: García-Almeida
authors.forename: G
authors.initials: G
authors.lastname: Ayala
authors.forename: R
authors.initials: R
authors.lastname: Fernández-Roblas
authors.forename: I
authors.initials: I
authors.lastname: Gadea
authors.forename: A
authors.initials: A
authors.lastname: Celdrán
authors.forename: E
authors.initials: E
authors.lastname: Gómez-Barrena
authors.forename: J
authors.initials: J
authors.lastname: Esteban
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D006801:Humans; D008124:Locomotion; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification / Q000502:physiology*; D009164:Mycobacterium Infections / Q000382:microbiology; D010860:Pigments, Biological / Q000096:biosynthesis
chemical_list: D010860:Pigments, Biological