Fetal motor activity and maternal cortisol.
The contemporaneous association between maternal salivary cortisol and fetal motor activity was examined at 32 and 36 weeks gestation. Higher maternal cortisol was positively associated with the amplitude of fetal motor activity at 32 weeks, r(48) = .39, p < .01, and 36 weeks, r(77) = .27, p < .05, and the amount of time fetuses spent moving at 32 weeks during the 50 min observation period, r(48) = 33, p < .05. Observation of periods of unusually intense fetal motor activity were more common in fetuses of women with higher cortisol, Mann-Whitney U = 58.5. There were no sex differences in fetal motor activity, but the associations between maternal cortisol and fetal motor amplitude and overall movement were significantly stronger for male than female fetuses.
DiPietro
Janet A
JA
Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. jdipietr@jhsph.edu
Kivlighan
Katie T
KT
Costigan
Kathleen A
KA
Laudenslager
Mark L
ML
D000328:Adult; D005260:Female; D005324:Fetal Movement / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D011247:Pregnancy; D012463:Saliva / Q000378:metabolism; D012737:Sex Factors; D013315:Stress, Psychological / Q000378:metabolism; D055815:Young Adult
D006854:Hydrocortisone