title: How successful are current ankle replacements?: a systematic review of the literature.
abstract: Total ankle arthroplasty provides an alternative to arthrodesis for management of ankle arthritis. What is the outcome of total ankle arthroplasty implants currently in use? We conducted a systematic literature search of studies reporting on the outcome of total ankle arthroplasty. We included peer-reviewed studies reporting on at least 20 total ankle arthroplasties with currently used implants, with a minimum followup of 2 years. The Coleman Methodology Score was used to evaluate the quality of the studies. Thirteen Level IV studies of overall good quality reporting on 1105 total ankle arthroplasties (234 Agility, 344 STAR, 153 Buechel-Pappas, 152 HINTEGRA, 98 Salto, 70 TNK, 54 Mobility) were included. Residual pain was common (range, 27%-60%), superficial wound complications occurred in 0% to 14.7%, deep infections occurred in 0% to 4.6% of ankles, and ankle function improved after total ankle arthroplasty. The overall failure rate was approximately 10% at 5 years with a wide range (range, 0%-32%) between different centers. Superiority of an implant design over another cannot be supported by the available data.
  
  
  METHODS
  Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
authors.affiliation: Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, 275 Bancroft Road, London E1 4DG, UK.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Gougoulias
authors.forename: Anil
authors.initials: A
authors.lastname: Khanna
authors.forename: Nicola
authors.initials: N
authors.lastname: Maffulli
mesh_terms: D000843:Ankle Joint / Q000601:surgery*; D001172:Arthritis, Rheumatoid / Q000601:surgery; D019643:Arthroplasty, Replacement / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods*; D016206:Databases, Bibliographic; D005500:Follow-Up Studies; D006801:Humans; D007595:Joint Prosthesis; D010003:Osteoarthritis / Q000601:surgery; D017063:Outcome Assessment, Health Care; D010149:Postoperative Pain / Q000209:etiology; D017060:Patient Satisfaction; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016032:Randomized Controlled Trials as Topic; D013530:Surgical Wound Infection / Q000209:etiology; D016896:Treatment Outcome