title: Clinical study comparing the efficacy of two denture adhesives in complete denture patients.
abstract: OBJECTIVE
  The aim of this study was to compare the efficacy of two denture adhesives in edentulous patients wearing complete maxillary and mandibular dentures.
  
  
  METHODS
  Twenty-four edentulous patients were treated with complete dentures following a standardized protocol. Resistance to dislodgement of both dentures was measured in simulated functional movements by means of a gnathometer and a dynamometer. These outcome measurements were assessed first without the adhesive and then after two successive 2-week periods of using a randomly assigned denture adhesive in a crossover experimental design. The adhesives used were a standard one (Kukident Classic) and a new adhesive with a similar formulation but different physical characteristics (Kukident Pro).
  
  
  RESULTS
  Twenty-four patients (mean age: 58 years) participated in this study. Gnathometer results demonstrated significant differences between the nonadhesive group and both the experimental adhesive (P = .008) and the control adhesive groups (P = .021). Differences between both adhesive groups were not significant (P = .161). Dynamometer results showed highly significant differences between the maxillary and mandibular dentures in both the nonadhesive group and the two adhesive groups (P =or< .0001). Similarly, highly significant differences were found when any of the adhesive groups were compared with the nonadhesive group (P = .0001). The patient subjective evaluation was very favorable for both adhesives.
  
  
  CONCLUSIONS
  This study confirms the predicted and expected improvement in the stability and retention of well-fitting complete dentures with the adjunctive use of adhesives. The observed and recorded improvements with the new adhesive as compared to the traditional one were not statistically significant.
authors.affiliation: Department of Prosthodontics, Faculty of Odontology, University Complutense of Madrid, Spain. gpradies@odon.ucm.es
authors.forename: Guillermo
authors.initials: G
authors.lastname: Pradíes
authors.forename: Ignacio
authors.initials: I
authors.lastname: Sanz
authors.forename: Ofelia
authors.initials: O
authors.lastname: Evans
authors.forename: Francisco
authors.initials: F
authors.lastname: Martnez
authors.forename: Mariano
authors.initials: M
authors.lastname: Sanz
mesh_terms: D000269:Adhesives / Q000737:chemistry / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D001628:Beverages; D001732:Bite Force; D002482:Cellulose / Q000737:chemistry; D018592:Cross-Over Studies; D003820:Denture Cleansers / Q000627:therapeutic use; D003781:Denture Retention; D003826:Denture, Complete, Lower; D003827:Denture, Complete, Upper; D004311:Double-Blind Method; D006801:Humans; D008298:Maleates / Q000737:chemistry; D008875:Middle Aged; D009066:Mouth, Edentulous / Q000534:rehabilitation; D009910:Oral Hygiene; D017060:Patient Satisfaction; D011095:Polyethylenes / Q000737:chemistry; D013314:Stress, Mechanical; D016896:Treatment Outcome; D014783:Viscosity; D017155:Wettability
chemical_list: D000269:Adhesives; D003820:Denture Cleansers; D008298:Maleates; D011095:Polyethylenes; D002482:Cellulose; C043105:poly(methyl vinyl ether-co-maleic anhydride)