Pediatric pulmonary arterial hypertension--a review.
Pulmonary arterial hypertension (PAH) afflicts thousands of children worldwide. The pathophysiology involves intravascular proliferation and remodeling leading to an increase in pulmonary vascular resistance which if left untreated results in right heart failure and death. Signs and symptoms are subtle as the disease progresses to irreversible lung damage. There is no cure for PAH, however newer methods of treatment can successfully manage these patients and delay progression of the disease process.
Ferns
Sunita Juliana
SJ
Department of Pediatrics, University of Illinois at Chicago, 840 St, Wood St, Chicago IL 60612, USA. sjulianaferns@yahoo.com
Wehrmacher
William H
WH
Serratto
Maria
M
D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology
D000959:Antihypertensive Agents