Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4'-epimerase (GALE) activities.
OBJECTIVE
The aim of our study was to determine whether the activities of galactose-1-phosphate uridyltransferase and UDP-galactose-4'-epimerase are correlated, and in what way they may influence one another.


METHODS
Enzyme activities were measured in red blood cells from 214 individuals.


RESULTS
A statistically significant (p<0.001) positive correlation was observed between GALT and GALE activities.


CONCLUSIONS
Our results suggest that GALT and GALE activities are correlated and that GALE activity has a greater impact on GALT activity than vice versa.
Prodan-Zitnik
Irena
I
Department of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia. irena.prodan.zitnik@ffa.uni-lj.si
Karas-Kuzelicki
Natasa
N
Lukac-Bajalo
Jana
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005690:Galactose / Q000378:metabolism; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000201:enzymology; D008875:Middle Aged; D013223:Statistics as Topic; D014534:UDPglucose 4-Epimerase / Q000378:metabolism*; D005694:UTP-Hexose-1-Phosphate Uridylyltransferase / Q000378:metabolism*; D055815:Young Adult
D005694:UTP-Hexose-1-Phosphate Uridylyltransferase; D014534:UDPglucose 4-Epimerase; D005690:Galactose