title: Bone material properties and fracture analysis: needle insertion for spinal surgery.
abstract: The effectiveness of percutaneous needle-based therapy and biopsy is demonstrated in a wide variety of medical problems including spinal disorders. Combined with osteoporosis, spinal disorders are increasingly prevalent as our society ages. However, the final position of the needle depends on a complex interplay of material properties of the bone and/or pathology, as well as the shape and material of the needle, and the insertion dynamics. This paper is a survey of the literature in the area of bone material properties and needle/bone interaction in the context of needle placement. It describes research findings on bone material properties and fractures using micro-CT imaging, and integrative imaging. This review paper also discusses the feasibility of using computational methods to predict fracture by simulating needle placement on any patient-specific model with both geometrical and mechanical properties approximating those of the patient's anatomy.
authors.affiliation: Centre for Biomedical Materials Applications and Technology, Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore. mpetsh@nus.edu.sg
authors.forename: S H
authors.initials: SH
authors.lastname: Teoh
authors.forename: C K
authors.initials: CK
authors.lastname: Chui
mesh_terms: D000818:Animals; D003198:Computer Simulation; D006801:Humans; D007796:Laminectomy / Q000009:adverse effects* / Q000295:instrumentation*; D008954:Models, Biological; D009339:Needles / Q000009:adverse effects*; D016103:Spinal Fractures / Q000209:etiology* / Q000503:physiopathology*; D013131:Spine / Q000503:physiopathology*