title: Outcome and prognostic factors in the conservative treatment of breast cancer.
abstract: BACKGROUND
  The aim of this retrospective study is to evaluate the results and identify prognostic factors in early breast cancer.
  
  
  METHODS
  One hundred breast cancers, 79 stage I and 21 stage II, had a conservative treatment between September 1993 and February 1996. Median age was 57 years; median tumor size 15 mm. Pathology was infiltrating ductal carcinoma in 88%. All patients underwent a conservative surgery followed by external radiotherapy. Twenty-eight patients received adjuvant chemotherapy and 64 patients received hormonal therapy. The median follow-up was 100 months.
  
  
  RESULTS
  The 10 years overall survival rate was 85% and the metastasis free survival rate was 88.5%. The 10 years local control rate was 85.7%. Women less than 45 years old had a worse prognosis.
  
  
  CONCLUSIONS
  These high rates of survival and local control confirm that breast conservation therapy yields favorable results, and that age is a major risk factor in women with early breast cancer.
authors.affiliation: *Radiation Oncology Department, Hôtel-Dieu de France, University Hospital, Beirut, Lebanon. nasre@inco.com.lb
authors.forename: Elie
authors.initials: E
authors.lastname: Nasr
authors.forename: Dolly
authors.initials: D
authors.lastname: Nasr
authors.forename: Fares
authors.initials: F
authors.lastname: Azoury
authors.forename: Georges
authors.initials: G
authors.lastname: Fares
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome