Human bocavirus: a cause of severe asthma exacerbation in children.
Real-time polymerase chain reaction for human bocavirus (HBoV) was performed in nasopharyngeal aspirate specimens from 166 children over 2 years of age hospitalized for severe asthma exacerbation. Whereas HBoV was detected in 21 of these children (13%), it was found in only 1 of 50 ambulatory children with stable asthma (2%), suggesting a major role of HBoV in acute exacerbations in asthmatic children.
Vallet
Christelle
C
Pediatric Unit, Paris Descartes University and AP-HP Saint Vincent de Paul-Cochin Hospital, Paris, France.
Pons-Catalano
Charlotte
C
Mandelcwajg
Alexis
A
Wang
Andrew
A
Raymond
Josette
J
Lebon
Pierre
P
Gendrel
Dominique
D
D000293:Adolescent; D001249:Asthma / Q000821:virology*; D052660:Bocavirus / Q000235:genetics / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000302:isolation & purification; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D009305:Nasopharynx / Q000821:virology*; D010322:Parvoviridae Infections / Q000453:epidemiology*; D016133:Polymerase Chain Reaction; D011446:Prospective Studies; D012621:Seasons; D012720:Severity of Illness Index
D004279:DNA, Viral