title: Whipple disease of the central nervous system: an unusual occurrence in association with acquired immune deficiency syndrome.
abstract: Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.
authors.affiliation: Department of Neurosurgery, LSU Health Science Center-Shreveport, Louisiana 71130-3932, USA. bguthi@lsuhsc.edu
authors.forename: Bharat
authors.initials: B
authors.lastname: Guthikonda
authors.forename: Emilie
authors.initials: E
authors.lastname: Rouah
authors.forename: Bhuvanaswari
authors.initials: B
authors.lastname: Krishnan
authors.forename: Suzanne Z
authors.initials: SZ
authors.lastname: Powell
authors.forename: J Clay
authors.initials: JC
authors.lastname: Goodman
authors.forename: Shankar P
authors.initials: SP
authors.lastname: Gopinath
authors.forename: Richard K
authors.initials: RK
authors.lastname: Simpson
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D000328:Adult; D015153:Blotting, Western; D015704:CD4 Antigens / Q000276:immunology; D002494:Central Nervous System Infections / Q000382:microbiology / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008061:Whipple Disease / Q000150:complications* / Q000382:microbiology / Q000473:pathology*
chemical_list: D015704:CD4 Antigens