title: The interdisciplinary treatment of unruptured intracranial aneurysms.
abstract: BACKGROUND
  The purpose of this article is to present the results of microsurgical clipping or endovascular coil obliteration of unruptured intracranial aneurysms (UIA), in a single cerebrovascular center with regard to successful obliteration and periprocedural complications.
  
  
  METHODS
  Data concerning patients with UIA were recorded in the neurovascular database of the neurosurgical department at the University of Frankfurt. The outcome of treatment was assessed with the modified Rankin Scale.
  
  
  RESULTS
  126 patients were treated by open surgery and 74 patients by endovascular coil obliteration. After treatment, the rate of new, mostly transient neurological deficits was 5%, and there were no deaths related to any treatment in this series. The outcome was good in 124 (98.4%) of the surgically treated patients and 73 (98.6%) of the endovascularly treated patients, and only 3 patients (1.5%) had a treatment-related unfavorable outcome. 98% of the treated aneurysms were satisfactorily obliterated. Seven endovascularly treated patients required retreatment because of coil compaction leading to recanalization of the aneurysm.
  
  
  CONCLUSIONS
  The majority of patients with unruptured intracranial aneurysms, even complex ones, can be treated by microsurgery or endovascular aneurysm obliteration with very good clinical results and a very low percentage of unfavorable outcomes. With careful patient selection and individualized assignment of the best form of treatment to each patient, we were able to achieve a low overall complication rate and a very high rate of obliteration in our specialized neurovascular center.
authors.affiliation: Klinik für Neurochirurgie, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main, Schleusenweg 2-16, Frankfurt/Main, Germany.
authors.forename: Volker
authors.initials: V
authors.lastname: Seifert
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Gerlach
authors.forename: Andreas
authors.initials: A
authors.lastname: Raabe
authors.forename: Erdem
authors.initials: E
authors.lastname: Güresir
authors.forename: Jürgen
authors.initials: J
authors.lastname: Beck
authors.forename: Andrea
authors.initials: A
authors.lastname: Szelényi
authors.forename: Matthias
authors.initials: M
authors.lastname: Setzer
authors.forename: Hartmut
authors.initials: H
authors.lastname: Vatter
authors.forename: Richard
authors.initials: R
authors.lastname: Du Mesnil de Rochemont
authors.forename: Friedhelm
authors.initials: F
authors.lastname: Zanella
authors.forename: Matthias
authors.initials: M
authors.lastname: Sitzer
authors.forename: Joachim
authors.initials: J
authors.lastname: Berkefeld