Temperature-dependent vesicle response to surface topography.
We have examined the deformation of vesicles on surface topography. From known vesicle shape dynamics, we expect temperature to play a major role; however, when cooling vesicles in the presence of a low-permeability solute, the mechanism of deflation is not clear. We investigate giant unilamellar vesicles on topography to quantify their cooling over a range of temperatures. The volume constraints point to a transient defect pore model as being responsible for vesicle deflation over the temperature range studied.
Gillmor
Susan D
SD
Department of Chemistry, George Washington University, 725 21st Street, N.W., Washington, DC 20052, USA. sdgill@gwu.edu
Heetderks
Julia J
JJ
Weiss
Paul S
PS