Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
Cerebral artery occlusion in childhood, particularly in the posterior circulation, is a rare neurological complication of Mycoplasma pneumoniae infection. A genetic defect in the methylenetetrahydrofolate reductase gene could result in hyperhomocysteinemia and increased risk of stroke. We report a patient with posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with a homozygous, methylenetetrahydrofolate reductase gene mutant type.
Ryu
Ju Seok
JS
Department of Physical Medicine and Rehabilitation, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Kim
Ha Jung
HJ
Sung
In Young
IY
Ko
Tae Sung
TS
D000293:Adolescent; D001921:Brain / Q000098:blood supply / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D020762:Infarction, Posterior Cerebral Artery / Q000209:etiology* / Q000235:genetics* / Q000473:pathology; D018810:Magnetic Resonance Angiography; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D020125:Mutation, Missense; D009175:Mycoplasma Infections / Q000150:complications*; D009177:Mycoplasma pneumoniae; D017422:Sequence Analysis, DNA
D042965:Methylenetetrahydrofolate Reductase (NADPH2)