Assignment of backbone (1)H, (13)C and (15)N resonances of human IgG1 Fc (51.4 kDa).
Here we report the NMR resonance assignments for the Fc region of human IgG1 expressed in E. coli, a 51.4 kDa dimer in solution (residues 221-447). The assignments have been deposited in the BioMagResBank with a BMRB accession number of 15514.
Liu
Dingjiang
D
Department of Pharmaceutics, Amgen Inc, Thousand Oaks, CA 91320, USA. liud@amgen.com
Cocco
Melanie J
MJ
Rosenfied
Robert
R
Lewis
Jeffery K
JK
Ren
Da
D
Li
Luke
L
Remmele
Richard L
RL
Brems
David N
DN
D000595:Amino Acid Sequence; D002247:Carbon Isotopes / Q000737:chemistry; D002352:Carrier Proteins / Q000737:chemistry*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D017434:Protein Structure, Tertiary; D011522:Protons
D002247:Carbon Isotopes; D002352:Carrier Proteins; D007141:Immunoglobulin Fc Fragments; D009587:Nitrogen Isotopes; D011522:Protons; C029702:prolactin-binding protein