Biofilm development by clinical strains of non-pigmented rapidly growing mycobacteria.
The relationship between clinical significance of non-pigmented, rapidly growing mycobacteria (NPRGM), in vitro biofilm development and sliding motility was evaluated in this study. One hundred and sixty-eight clinical strains of NPRGM were included. Forty-one of these were clinically significant isolates. Biofilm was formed by 123 strains. Seventy-six biofilm-positive and 25 biofilm-negative strains showed sliding motility. There was a relationship between clinical significance and biofilm development (p <0.000,001), sliding motility (p 0.0037) and species (p <0.000,001). No relationship was found between motility and biofilm development. The ability to develop biofilm is a characteristic that can have importance in the development of infections caused by NPRGM.
Martín-de-Hijas
N Z
NZ
Department of Clinical Microbiology, Fundación Jiménez Díaz-UTE, Madrid, Spain.
García-Almeida
D
D
Ayala
G
G
Fernández-Roblas
R
R
Gadea
I
I
Celdrán
A
A
Gómez-Barrena
E
E
Esteban
J
J
D018441:Biofilms / Q000254:growth & development*; D006801:Humans; D008124:Locomotion; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification / Q000502:physiology*; D009164:Mycobacterium Infections / Q000382:microbiology; D010860:Pigments, Biological / Q000096:biosynthesis
D010860:Pigments, Biological