[Determination of avermectin residues in tea by ultra-performance liquid chromatography-electrospray tandem mass spectrometry].
A simple and rapid analytical method for the simultaneous determination of abamectin, emamectin, eprinomectin, ivermectin, doramectin and moxidectin residues in tea by ultra-performance liquid chromatography-electrospray tandem mass spectrometry (UPLC/ESI-MS/MS) has been developed. The avermectins were extracted from the tea with acetonitrile after the tea was infiltrated in saturated aqueous NaCl solution, then cleaned up with a C18 solid phase extraction cartridge. The linear ranges were 2.0-50 microg/L and the correlation coefficients were all above 0.9920. Several UPLC-MS/MS conditions that included the mobile phase, monitor ions and the selection of calibration of the measurement were studied. The average recoveries and the relative standard deviations ranged from 61.7% to 85.4% and from 9.37% to 17.19%, respectively, in spiked samples at the concentrations of 5, 10, 20 microg/kg for moxidectin and 2, 5, 10 microg/kg for other analytes. This method is suitable for the determination of avermeetin residues in tea.
Yang
Fang
F
Fujian Entry-Exit Inspection and Quarantine Bureau, Fuzhou 350001, China. yffjciq@gmail.com
Yang
Shoushen
S
Lin
Yonghui
Y
Zheng
Danping
D
Lu
Shengyu
S
Huang
Zhiqiang
Z
Zhang
Ying
Y
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004187:Disaccharides / Q000032:analysis; D004350:Drug Residues / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000032:analysis; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013662:Tea / Q000737:chemistry*
D004187:Disaccharides; D013662:Tea; D007559:Ivermectin; C019264:avermectin; C101434:eprinomectin; C443359:emamectin