Uterine adenomyosis in persistence of dysmenorrhea after surgical excision of pelvic endometriosis and colorectal resection.
OBJECTIVE
To determine whether the presence of uterine adenomyosis may impair the amelioration of pain symptoms after laparoscopic excision of pelvic endometriosis combined with colorectal resection.


METHODS
This prospective study included 50 women with bowel endometriosis with or without uterine adenomyosis. Presence of uterine adenomyosis was investigated by magnetic resonance imaging. Patients underwent excision of pelvic endometriosis and colorectal resection; some patients with focal adenomyosis underwent uterine surgery. Pain symptoms and gastrointestinal complaints were evaluated before surgery and at 6, 12 and 18 months' follow-up.


RESULTS
At 6-month follow-up, dysmenorrhea significantly improved in women without uterine adenomyosis and in those with adenomyosis that was excised at surgery; this improvement persisted at 18 months' followup. No significant improvement in dysmenorrhea was observed in women with adenomyosis not excised at surgery. Deep dyspareunia and chronic pelvic pain significantly improved at follow-up in all study groups. Most of gastrointestinal symptoms improved or disappeared at 6 months' follow-up; the improvement in gastrointestinal function persisted at 18 months' follow-up.


CONCLUSIONS
Excision of pelvic endometriosis combined with bowel resection significantly improves chronic pelvic pain, dyspareunia and gastrointestinal symptoms; however, the presence of uterine adenomyosis may determine persistence of dysmenorrhea.
Ferrero
Simone
S
Department of Obstetrics and Gynecology, San Martino Hospital and University of Genoa, Largo R. Benzi 1, 16132 Genoa, Italy. dr@simoneferrero.com
Camerini
Giovanni
G
Menada
Mario Valenzano
MV
Biscaldi
Ennio
E
Ragni
Nicola
N
Remorgida
Valentino
V
D000328:Adult; D003082:Colectomy; D003108:Colonic Diseases / Q000601:surgery*; D004412:Dysmenorrhea / Q000209:etiology / Q000517:prevention & control*; D004715:Endometriosis / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010147:Pain Measurement; D010388:Pelvis; D012002:Rectal Diseases / Q000601:surgery*; D012307:Risk Factors; D016896:Treatment Outcome; D014591:Uterine Diseases / Q000150:complications* / Q000601:surgery