title: [Is hepatomegaly a prognosis factor of chronic myeloid leukaemia among African blacks?].
abstract: It acts of a retrospective study relating to 74 patients reached of chronic Leukaemia myeloid (LMC) over one 5 year period followed in the clinical service of hematology of the University Hospital of Yopougon (Abidjan, Ivory Coast). The splenomegaly is quasi-constant in chronic phase of the disease often associated hepatomegaly in 20.27% of the cases which constitutes a pejorative factor of the LMC. Indeed, the hyperleukocytosis of more than 300,000 white globules is correlated with the presence of hepatomegaly (p=0.0005) with risks of portal hypertension. 80% of the patients carrying the LMC with a clinical hepatomegaly in chronic phase of the disease have against an incomplete hematologic remission 20% of complete remission (P = 0.002) among patients without hepatomegaly. The strong rate of death (73.33%) recorded occurred among patients carrying a hepatomegaly against 15.25% of death without hepatomegaly (P = 0.0001). The overall rates Total survival is on average 17 months against 20 months 28 days in the event of absence of the hepatomegaly (P = 0.0001).
authors.affiliation: Service d’Hématologie clinique CHU Yopougon 21 BP 632 Abidjan, Côte d’Ivoire. clotairedanho@yahoo.fr
authors.forename: D C
authors.initials: DC
authors.lastname: Nanho
authors.forename: F S
authors.initials: FS
authors.lastname: N'Diaye
authors.forename: A
authors.initials: A
authors.lastname: Tolo
authors.forename: G S
authors.initials: GS
authors.lastname: Kouamenan
authors.forename: Y M
authors.initials: YM
authors.lastname: Sekongo
authors.forename: R
authors.initials: R
authors.lastname: Ayemou
authors.forename: D
authors.initials: D
authors.lastname: Meite
authors.forename: P
authors.initials: P
authors.lastname: Kouehion
authors.forename: B
authors.initials: B
authors.lastname: Kouakou
authors.forename: K G
authors.initials: KG
authors.lastname: Koffi
authors.forename: I
authors.initials: I
authors.lastname: Sanogo
authors.forename: Amadou
authors.initials: A
authors.lastname: Sangare
mesh_terms: D000293:Adolescent; D000328:Adult; D044383:Black People; D002648:Child; D002675:Child, Preschool; D006529:Hepatomegaly / Q000209:etiology*; D006801:Humans; D007223:Infant; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000401:mortality*; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D055815:Young Adult