Transgenesis in parasitic nematodes: building a better array.
In spite of recent progress in the development of transgenesis in parasitic nematodes, several impediments remain before this methodology can become a practical and widely employed tool in parasitology. Recently published studies on transgenesis in the necromenic nematode Pristionchus pacificus from the laboratory of Ralf Sommer highlight several leads that might be valuable as efforts to refine current systems in obligate parasites go forward.
Lok
James B
JB
Department of Pathobiology, University of Pennsylvania, Philadelphia, 19104, USA. jlok@vet.upenn.edu
D000818:Animals; D018014:Gene Transfer Techniques; D017238:Genes, Helminth; D023281:Genomics / Q000379:methods*; D009348:Nematoda / Q000235:genetics*; D013045:Species Specificity; D013321:Strongyloides / Q000235:genetics; D019076:Transgenes