title: Uses of nanoparticles for central nervous system imaging and therapy.
abstract: Applications of nanotechnology to medicine are leading to novel means of imaging living systems and of delivering therapy. Much nanotechnology research is focused on methods for imaging central nervous system functions and disease states. In this review, the principles of nanoparticle design and function are discussed with specific emphasis on applications to neuroradiology. In addition to innovative forms of imaging, this review describes therapeutic uses of nanoparticles, such as drug delivery systems, neuroprotection devices, and methods for tissue regeneration.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, NC 27710-3808, USA. prove001@mc.duke.edu
authors.forename: J M
authors.initials: JM
authors.lastname: Provenzale
authors.forename: G A
authors.initials: GA
authors.lastname: Silva
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000628:therapy*; D003287:Contrast Media; D003952:Diagnostic Imaging / Q000379:methods*; D004337:Drug Carriers / Q000737:chemistry*; D007089:Image Enhancement / Q000379:methods; D050997:Nanomedicine / Q000639:trends*; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use*; D011859:Radiography
chemical_list: D003287:Contrast Media; D004337:Drug Carriers