title: Behavior therapy for obesity: where are we now?
abstract: OBJECTIVE
  To describe the short-term and long-term results of lifestyle modification for obesity.
  
  
  RESULTS
  Randomized controlled trials, which compared different diet and activity interventions were reviewed. Studies that investigated the efficacy of new technologies to provide lifestyle modification, such as web-based delivery, also were examined.
  
  
  CONCLUSIONS
  In general, comprehensive lifestyle modification programs delivered in person induce a loss of approximately 10% of initial weight in 16-26 weeks of treatment. The use of portion-controlled diets, which typically involve the use of meal replacement products, was associated with significantly larger weight losses in the short term. In contrast, interventions delivered via the Internet induced a loss of approximately 5%. However, web-based programs appear to have potential in facilitating the continuation on patient-provider contact, which along with high levels of physical activity, appear to be key strategies for successful long-term weight control. Recent studies also have suggested that the combination of lifestyle modification with long-term use of pharmacotherapy holds promise for maximizing initial weight losses and promoting long-term maintenance.
authors.affiliation: Department of Psychiatry, Center for Weight and Eating Disorders, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. dsarwer@mail.med.upenn.edu
authors.forename: David B
authors.initials: DB
authors.lastname: Sarwer
authors.forename: Amy
authors.initials: A
authors.lastname: von Sydow Green
authors.forename: Marion L
authors.initials: ML
authors.lastname: Vetter
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Wadden
mesh_terms: D019440:Anti-Obesity Agents / Q000627:therapeutic use; D050110:Bariatric Surgery / Q000534:rehabilitation; D001521:Behavior Therapy / Q000379:methods / Q000639:trends*; D001835:Body Weight / Q000502:physiology; D003131:Combined Modality Therapy / Q000379:methods; D004032:Diet / Q000379:methods; D005247:Feeding Behavior / Q000502:physiology; D006801:Humans; D008019:Life Style; D009043:Motor Activity / Q000502:physiology; D009765:Obesity / Q000628:therapy*
chemical_list: D019440:Anti-Obesity Agents