title: Detection and susceptibility testing of Mycoplasma amphoriforme isolates from patients with respiratory tract infections.
abstract: Three isolates of Mycoplasma amphoriforme, a new Mycoplasma species rarely described to date, were obtained from respiratory tract specimens from two children and one adult with respiratory tract infections. Molecular methods were required to distinguish them from Mycoplasma pneumoniae. MICs of macrolides, tetracyclines and fluoroquinolones were identical to those for M. pneumoniae, except for that of ciprofloxacin, which was slightly more potent against M. amphoriforme. M. amphoriforme could possibly have been involved in one case of severe respiratory infection with sepsis, but further studies are needed to specify its role as a potential respiratory tract pathogen.
authors.affiliation: Laboratoire de Bactériologie EA 3671, Mycoplasma and Chlamydia Infections in Humans, Université Victor Segalen Bordeaux 2 and CHU de Bordeaux, Bordeaux, France. sabine.pereyre@u-bordeaux2.fr
authors.forename: S
authors.initials: S
authors.lastname: Pereyre
authors.forename: H
authors.initials: H
authors.lastname: Renaudin
authors.forename: A
authors.initials: A
authors.lastname: Touati
authors.forename: A
authors.initials: A
authors.lastname: Charron
authors.forename: O
authors.initials: O
authors.lastname: Peuchant
authors.forename: A Bon
authors.initials: AB
authors.lastname: Hassen
authors.forename: C
authors.initials: C
authors.lastname: Bébéar
authors.forename: C M
authors.initials: CM
authors.lastname: Bébéar
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D009174:Mycoplasma / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification* / Q000378:metabolism; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000382:microbiology*; D013754:Tetracyclines / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D024841:Fluoroquinolones; D018942:Macrolides; D013754:Tetracyclines