title: CYP2C9, CYP2C19, and ABCB1 genotype and hospitalization for phenytoin toxicity.
authors.affiliation: Center for Clinical Epidemiology & Biostatistics and Department of Biostatistics & Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Sean
authors.initials: S
authors.lastname: Hennessy
authors.forename: Charles E
authors.initials: CE
authors.lastname: Leonard
authors.forename: Cristin P
authors.initials: CP
authors.lastname: Freeman
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Metlay
authors.forename: Xin
authors.initials: X
authors.lastname: Chu
authors.forename: Brian L
authors.initials: BL
authors.lastname: Strom
authors.forename: Warren B
authors.initials: WB
authors.lastname: Bilker
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics*; D000368:Aged; D000369:Aged, 80 and over; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D016022:Case-Control Studies; D065731:Cytochrome P-450 CYP2C19; D065729:Cytochrome P-450 CYP2C9; D004247:DNA / Q000302:isolation & purification; D005260:Female; D005820:Genetic Testing; D014644:Genetic Variation; D005838:Genotype; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000378:metabolism; D010672:Phenytoin / Q000506:poisoning* / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D012306:Risk
chemical_list: C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D010672:Phenytoin; D004247:DNA; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19