title: Design of a protective cage for an intravascular axial flow blood pump to mechanically assist the failing Fontan.
abstract: Currently, no long-term mechanical bridge-to-transplant or bridge-to-recovery therapeutic alternative exists for failing single ventricles. A blood pump that would augment pressure in the cavopulmonary circulation is needed, and would lead to a reduction in elevated systemic venous pressure, and improve cardiac output. Thus, we are developing a collapsible, percutaneously inserted, axial flow blood pump to support the cavopulmonary circulation in adult patients with a failing single ventricle physiology. This collapsible axial flow pump is designed for percutaneous positioning. The outer protective cage will be designed with radially arranged filaments as touchdown surfaces to protect the vessel wall from the rotating components. This study examined the geometric characteristics of the protective cage of filaments and the impeller through the development and numerical analysis of 13 models. A blood damage analysis was also performed on selected geometric models to assess the probability of blood trauma. All models demonstrated an acceptable hydraulic performance by delivering 2-6 L/min at a rotational speed of 6000-10 000 rpm and generating pressure rise of 5-20 mm Hg. Expected trends in the hydraulic performance of the pump models were found. This study represents the initial first design phase of the impeller and protective cage of filaments. Validation of these flow and performance predictions will be completed in the next round of experimental testing with blood bag evaluation.
authors.affiliation: Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA, USA. althrock@vcu.edu
authors.forename: Amy L
authors.initials: AL
authors.lastname: Throckmorton
authors.forename: Ravi A
authors.initials: RA
authors.lastname: Kishore
mesh_terms: D000328:Adult; D003198:Computer Simulation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006352:Heart Ventricles / Q000503:physiopathology; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular