In vitro antimicrobial activity of calcium hydroxide mixed with different vehicles against Enterococcus faecalis and Candida albicans.
OBJECTIVE
The purpose of this in vitro study was to investigate antimicrobial activity of calcium hydroxide (CH) in combination with glycerin, chlorhexidine gluconate (CHX), cetrimide, or distilled water against Enterococcus faecalis and Candida albicans.


METHODS
Standard holes in the cultivated agar plates were filled with one of the CH preparations and control agents. The zones of microbial inhibition were measured after incubation period.


RESULTS
The CH preparations with glycerin and CHX demonstrated more antifungal activity than CH preparations with cetrimide and distilled water. The CH-glycerin preparations had no effect against E. faecalis, and CH-CHX preparation was the most effective medication.


CONCLUSIONS
Antimicrobial activity of CH may change with the type of the vehicle and against different microorganisms. Enterococcus faecalis was more resistant than C. albicans to CH preparations.
Turk
B Tugba
BT
Division of Endodontology, School of Dentistry, Ege University, Izmir, Turkey.
Sen
Bilge Hakan
BH
Ozturk
Tansel
T
D000891:Anti-Infective Agents, Local / Q000737:chemistry / Q000494:pharmacology*; D002126:Calcium Hydroxide / Q000737:chemistry / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry / Q000494:pharmacology; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D015169:Colony Count, Microbial; D004338:Drug Combinations; D013293:Enterococcus faecalis / Q000187:drug effects*; D005990:Glycerol / Q000737:chemistry / Q000494:pharmacology; D014677:Pharmaceutical Vehicles / Q000737:chemistry / Q000494:pharmacology*; D012387:Root Canal Filling Materials / Q000737:chemistry / Q000494:pharmacology*
D000891:Anti-Infective Agents, Local; D002593:Cetrimonium Compounds; D004338:Drug Combinations; D014677:Pharmaceutical Vehicles; D012387:Root Canal Filling Materials; C010882:chlorhexidine gluconate; D005990:Glycerol; D002126:Calcium Hydroxide; D002710:Chlorhexidine; D000077286:Cetrimonium