Angioplasty for renal artery fibromuscular dysplasia in older hypertensive patients.
OBJECTIVE
To describe the outcomes of treating patients with angioplasty who are older than 40 years with symptomatic/labile/refractory hypertension (HTN).


METHODS
Between 1999 and 2005, 28 patients underwent angioplasty for renal fibromuscular dysplasia (FMD). Patients were excluded if they had concomitant atherosclerotic renal artery stenosis (n = 4) or less than 1 month follow-up (n = 8).


RESULTS
The study group included 16 Caucasians (21 procedures; mean age 65.5 +/- 10.8 years; females = 88%). The cardiovascular risk factors include HTN (n = 13), smoking (n = 1), diabetes (n = 2), dyslipidemia (n = 8). The HTN was characterized as refractory (n = 15, 12 were symptomatic) and new-onset in 1 patient. The technical success rate was 100%. Over a median period of 12.8 months (range: 1.0-85.8), 18 (95%) procedures ''failed,'' of which 8 (42%) within 1 month and the rest in 1 year.


CONCLUSIONS
Angioplasty in symptomatic renal FMD in patients >40 years is associated with poor outcomes possibly due to early restenosis.
Thatipelli
M R
MR
Department of Cardiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Huettl
E A
EA
McKusick
M A
MA
Misra
S
S
D000368:Aged; D000792:Angiography; D017130:Angioplasty / Q000379:methods*; D001794:Blood Pressure; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D008297:Male; D012078:Renal Artery Obstruction / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome