title: Chemical constituents investigation of Daphne tangutica.
abstract: A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant.
authors.affiliation: Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.
authors.forename: Li
authors.initials: L
authors.lastname: Pan
authors.forename: Xiao Feng
authors.initials: XF
authors.lastname: Zhang
authors.forename: Ye
authors.initials: Y
authors.lastname: Deng
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Li Sheng
authors.initials: LS
authors.lastname: Ding
mesh_terms: D032364:Daphne / Q000737:chemistry*; D004224:Diterpenes / Q000302:isolation & purification; D038861:Medicine, Tibetan Traditional; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D004224:Diterpenes