title: Visceral leishmaniasis associated hemophagocytic syndrome in patients with chronic granulomatous disease.
abstract: Visceral leishmaniasis is a severe form of infection caused by a parasite endemic along the Mediterranean coast. Complications such as infection-associated hemophagocytic syndrome can occur despite correct therapy. We report visceral leishmaniasis-associated infection-associated hemophagocytic syndrome in 3 patients with chronic granulomatous disease.
authors.affiliation: Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Hospital, Barcelona, Spain. 37904amn@comb.es
authors.forename: Andrea
authors.initials: A
authors.lastname: Martín
authors.forename: Laura
authors.initials: L
authors.lastname: Marques
authors.forename: Pere
authors.initials: P
authors.lastname: Soler-Palacín
authors.forename: Isabel
authors.initials: I
authors.lastname: Caragol
authors.forename: Manuel
authors.initials: M
authors.lastname: Hernandez
authors.forename: Concepcion
authors.initials: C
authors.lastname: Figueras
authors.forename: Teresa
authors.initials: T
authors.lastname: Español
mesh_terms: D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D008297:Male; D011994:Recombinant Proteins
chemical_list: D000981:Antiprotozoal Agents; D011994:Recombinant Proteins; C068538:liposomal amphotericin B; D000666:Amphotericin B; D007371:Interferon-gamma