title: [A case of extranodal NK/T-cell lymphoma, nasal type, with skin ulceration and multiple nodules in the lung].
abstract: We report a rare case of extranodal NK/T-cell lymphoma, nasal type, with skin ulceration and multiple nodules in the lung, and will compare this case with others in the literature. A 54-year-old man was troubled with flare and swelling of his right arm for one month. He was referred to our hospital because of subcutaneous nodules with ulceration on the right arm, fever, and general fatigue. Chest radiograph revealed multiple nodular shadows in both lungs. The patient was admitted for further evaluation. Chest computed tomography revealed multiple nodules in both lungs with ground-glass opacities around some of them. Some nodules seemed to be clustered in the right lower lobe. Biopsy specimens of subcutaneous nodules and transbronchial biopsy specimens of pulmonary tissue demonstrated only extensive necrosis. A VATS lung biopsy from the right S9 was then taken. Pathological and immunohistological findings suggested a diagnosis of extranodal NK/T-cell lymphoma, nasal type (WHO classification), stage IVB. The patient was transferred to the department of hematology in another hospital for systemic chemotherapy, but died 2 months later.
authors.affiliation: Department of Respiratory Medicine, Hiratsuka Kyosai Hospital.
authors.forename: Reo
authors.initials: R
authors.lastname: Hamaguchi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Saito
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kegasawa
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ryujin
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Kurata
authors.forename: Hideyasu
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Akiko
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Yamazaki
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Jin
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Yoshimura
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D054391:Lymphoma, Extranodal NK-T-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055613:Multiple Pulmonary Nodules / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology*