title: [ACTH-dependent Cushing syndrome, a diagnostic challenge].
abstract: ACTH dependent Cushing syndrome accounts for approximately 80% of all Cushing syndrome. Distinguishing the pituitary origin from ectopic one is still a diagnosis problem in some cases, especially in bronchial carcinoids, because approximately 50% show cortisol suppresion after dexametasone and may be small and, therefore, difficult to detect in chest radiography. We present a case of a patient with ACTH dependent Cushing syndrome of difficult localization with usual diagnosis tests.
authors.affiliation: Sección de Endocrinología. Hospital Severo Ochoa. Leganés. Madrid. España. drsfuentes@gmail.com
authors.forename: Sergio
authors.initials: S
authors.lastname: Fuentes Tudanca
authors.forename: Purificación Martínez de Icaya
authors.initials: PM
authors.lastname: Ortiz de Urbina
authors.forename: Luis Muñoz
authors.initials: LM
authors.lastname: De Dios
authors.forename: Sergio
authors.initials: S
authors.lastname: Gallego Rodríguez
authors.forename: Míriam
authors.initials: M
authors.lastname: Pérez Pelayo
authors.forename: Dolores
authors.initials: D
authors.lastname: Del Olmo García
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001984:Bronchial Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D001999:Bronchoscopy; D002276:Carcinoid Tumor / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D003480:Cushing Syndrome / Q000209:etiology*; D003951:Diagnostic Errors; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D047748:Pituitary ACTH Hypersecretion / Q000175:diagnosis*; D011013:Pneumonectomy; D011859:Radiography; D019564:Unnecessary Procedures
chemical_list: D014408:Biomarkers, Tumor; D000324:Adrenocorticotropic Hormone