[Evaluation of left ventricular diastolic function in canine acute myocardial ischemia using velocity vector imaging and quantitative tissue velocity imaging].
OBJECTIVE
To assess the value of velocity vector imaging (VVI) and quantitative tissue velocity imaging (QTVI) in assessing left ventricular diastolic function of the dogs with acute myocardial ischemia.


METHODS
Six healthy mongrel dogs were subjected to ligation of the left circumflex artery or left anterior descending artery to induce coronary artery stenosis of varying degrees. The mean peak diastolic velocity (Em) of the ventricular walls around the mitral annulus was recorded with VVI or QTVI in the coronary blood flow. The left ventricular end diastolic pressure (LVEDP) was measured with pigtail catheter in the left ventricle.


RESULTS
As the coronary blood flow decreased, LVEDP was gradually increased, and Em measured by VVI or QTVI were also gradually decreased. A good linear correlation was shown between Em measured by VVI or QTVI and LVEDP (r=-0.834, P<0.001, and r=-0.68, P<0.001, respectively). A significant difference was observed in the correlation coefficient between VVI and QTVI (Z=2.625, P=0.0087).


CONCLUSIONS
VVI and QTVI both provide good noninvasive means for measuring left ventricular diastolic function. VVI, a new echocardiographic modality without angular dependence, is better than QTVI in evaluating left ventricular diastolic function.
Zhang
Chuan
C
Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. zhanglang19991999@yahoo.com.cn
Zha
Dao-Gang
DG
DU
Rong-Sheng
RS
Hu
Feng
F
Li
Sheng-Hui
SH
Wu
Xiao-Yuan
XY
Liu
Yi-Li
YL
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004452:Echocardiography / Q000379:methods*; D008297:Male; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D016277:Ventricular Function, Left