title: [Methicillin-resistant Staphylococcus aureus at a general hospital: epidemiological overview between 2000-2007].
abstract: BACKGROUND
  The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients is a significant problem due to its associated morbidity and mortality. It is important to know the recent MRSA epidemiology at a General Hospital.
  
  
  OBJECTIVE
  To determine the MRSA epidemiology at a Mexican general hospital from 2000 to 2007, in order to know if there is a significant trend in its proportion.
  
  
  METHODS
  Prevalence survey. The resistance to oxacillin was identified by the Kirby-Bauer's method. The specimens were classified by type and year of isolation. Trend statistics were used for analysis.
  
  
  RESULTS
  S. aureus was identified in 1,008 samples, being 301 resistant to oxacillin (30%, 95% Confidence Interval [CI], 25 to 35%). The proportion of MRSA went from 37% (95% CI, 29 to 44%) to 49% (95% CI, 40 to 58%) in the period of study (chi2 for trends = 6.676, p < 0.01). Specimens with the highest proportion of MRSA were blood and sterile liquids with 32% (95% CI, 26 to 39%), secretions with 29% (95% CI, 24 to 33%), and catheters with 21% (95% CI, 16 to 26%).
  
  
  CONCLUSIONS
  The proportion of MRSA has increased significantly. This leads to higher costs and morbi-mortality for the hospitalized patients. We require stricter policies to prevent transmission and to control the use of antibiotics.
authors.affiliation: Facultad de Medicina de León, Universidad de Guanajuato. micros_iesus@yahoo.com
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Alvarez
authors.forename: América Jazmín
authors.initials: AJ
authors.lastname: Ramírez
authors.forename: Miriam
authors.initials: M
authors.lastname: Mojica-Larrea
authors.forename: Jessica del Rocío
authors.initials: Jdel R
authors.lastname: Huerta
authors.forename: Jennifer Dayane
authors.initials: JD
authors.lastname: Guerrero
authors.forename: Ana Lilia
authors.initials: AL
authors.lastname: Rolón
authors.forename: Humberto
authors.initials: H
authors.lastname: Medina
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Muñoz
authors.forename: Juan Luis
authors.initials: JL
authors.lastname: Mosqueda
authors.forename: Alejandro Ernesto
authors.initials: AE
authors.lastname: Macías
authors.forename: José
authors.initials: J
authors.lastname: Sifuentes-Osornio
mesh_terms: D003428:Cross Infection / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D006769:Hospitals, General / Q000706:statistics & numerical data*; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D009017:Morbidity / Q000639:trends; D010068:Oxacillin / Q000494:pharmacology; D015995:Prevalence; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D010068:Oxacillin