Pustular blastomycosis.
Blastomycosis is an infection caused by the dimorphic fungus Blastomyces dermatitidis. Infection can disseminate to skin, where characteristic ulcerative and verrucous plaques, sometimes studded with pustules, are typically seen. Herein we report 3 patients, two children and one adult, with pustular blastomycosis. Their cutaneous lesions exhibited a pustular morphology at the onset and throughout the course of their illness, without evolution to more typical verrucous or ulcerative plaques. These patients all resided in Memphis, TN, the site of previous case reports of pustular blastomycosis.
Fisher
Kristopher R
KR
Division of Dermatology, Department of Medicine, University of Tennessee Health Science Center, 956 Court Ave, Coleman Bldg, Room D322, Memphis, TN 38163, USA.
Baselski
Vickie
V
Beard
Gwen
G
Chesney
Thomas M
TM
Threlkeld
Stephen C
SC
Skinner
Robert B
RB
D000208:Acute Disease; D000293:Adolescent; D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D001707:Biopsy, Needle; D001758:Blastomyces / Q000302:isolation & purification*; D001759:Blastomycosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007262:Infusions, Intravenous; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D015996:Survival Rate
D017964:Itraconazole; D000666:Amphotericin B