title: A rare but fatal case of granulomatous amebic encephalitis with brain abscess: the first case reported from Turkey.
abstract: The incidence of protozoal and helminthic infestations of the central nervous system (CNS) is less than 1%, but these infestations tend to follow a fatal course. They are more common among children, the elderly and immunocompromised individuals. CNS infections due to Entamoeba histolytica have been known for a long time. In recent years, especially in developing countries, there has been an increase in CNS infections due to free-living amebas (FLAs). Acute CNS infection due to Naegleria fowleri, which ends in death within 2-7 days, is termed primary amebic meningoencephalitis (PAM); subacute or chronic CNS infections due to Acanthamoeba spp, Balamuthia mandrillaris, and Sappinia diploidea, which occasionally cause cerebral abscess, are termed granulomatous amebic encephalitis (GAE). This paper presents a case of GAE with abscess formation in a 75-year-old male patient.
authors.affiliation: Başkent University, School of Medicine, Neurosurgery Department, Ankara, Turkey. saricafb@gmail.com
authors.forename: Feyzi Birol
authors.initials: FB
authors.lastname: Sarica
authors.forename: Kadir
authors.initials: K
authors.lastname: Tufan
authors.forename: Melih
authors.initials: M
authors.lastname: Cekinmez
authors.forename: Bülent
authors.initials: B
authors.lastname: Erdoğan
authors.forename: Mehmet Nur
authors.initials: MN
authors.lastname: Altinörs
mesh_terms: D000368:Aged; D000562:Amebiasis / Q000469:parasitology* / Q000473:pathology*; D000818:Animals; D001706:Biopsy; D001922:Brain Abscess / Q000469:parasitology* / Q000473:pathology*; D017809:Fatal Outcome; D006099:Granuloma / Q000469:parasitology / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016848:Naegleria fowleri; D014421:Turkey