[BK virus and renal transplantation].
BK virus (BKV) is a subtype of papovaviridae. The latent and asymptomatic infection of BKV is common among healthy people. The incidence of BKV re-activation in renal transplant recipients ranges 10%-68%. About 1%-7% of renal transplant recipients will suffer from BKV-associated nephropathy (BKVAN), and half of them will experience graft failure. This paper summarizes the re-activation mechanism of BKV as well as the risk factors, pathology, diagnosis, and treatment of BKVAN.
Liu
Hang
H
Department of Transplantation, Tianjin First Center Hospital, Tianjin 300192, China. liuhang66@yahoo.com.cn
Shi
Yi
Y
Li
Chao-yang
CY
Wang
Jian-li
JL
D001739:BK Virus / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000821:virology; D016030:Kidney Transplantation; D027601:Polyomavirus Infections / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011183:Postoperative Complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy / Q000821:virology; D012307:Risk Factors; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D014775:Virus Activation