title: Robotic approach for cervical cancer: comparison with laparotomy: a case control study.
abstract: OBJECTIVE
  To compare the surgical outcome of robotic radical hysterectomy (RRH) versus abdominal radical hysterectomy (ARH) for the treatment of early stage cervical cancer.
  
  
  METHODS
  A prospective collection of data of all RRH for stages IA2-IIA cervical cancer was done. The procedures were performed at the European Institute of Oncology, Milan, Italy, between November 1, 2006 and February 1, 2009.
  
  
  RESULTS
  A total of 40 RRH were analyzed, and compared with 40 historic ARH cases. The groups did not differ significantly in body mass index, stage, histology, or intraoperative complications, but in age (p=0.035). The mean (SD) operative time was significantly shorter for ARH than RRH, 199.6 (65.6) minutes and 272.27 (42.3) minutes respectively (p=0.0001). The mean (SD) estimated blood loss (EBL) was 78 ml (94.8) in RRH group and 221.8 ml (132.4) in ARH. This difference was statistically significant in favor of RRH group (p<0.0001). Statistically significantly higher number of pelvic lymph nodes was removed by ARH than by RRH, mean (SD) 26.2 (11.7) versus 20.4 (6.9), p<0.05. Mean length of stay was significantly shorter for the RRH group (3.7 versus 5.0 days, p<0.01). There was no significant difference in terms of postoperative complications between groups.
  
  
  CONCLUSIONS
  This study shows that RRH is safe and feasible. However, a comparison of oncologic outcomes and cost-benefit analysis is still needed and it has to be carefully evaluated in the future.
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Maggioni
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: lucasminig@yahoo.com.
authors.forename: Lucas
authors.initials: L
authors.lastname: Minig
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Vanna
authors.initials: V
authors.lastname: Zanagnolo
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Peiretti
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Sanguineti
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Bocciolone
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Colombo
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Landoni
authors.affiliation: Gynecology Department, European Institute of Oncology, Milan, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Roviglione
authors.affiliation: Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
authors.forename: Jorge Ivan
authors.initials: JI
authors.lastname: Vélez
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods*; D007813:Laparotomy / Q000009:adverse effects / Q000379:methods; D007902:Length of Stay; D008875:Middle Aged; D009367:Neoplasm Staging; D011184:Postoperative Period; D011446:Prospective Studies; D012371:Robotics / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*