Cerebroretinal microangiopathy with calcifications and cysts: demonstration of radiological progression.
Cerebroretinal microangiopathy with calcifications and cysts is a rare entity with progressive calcifications, enhancing subcortical cysts, and leukoencephalopathy. We present the oldest reported woman with this disorder, with 10 years of imaging documenting progression. This reveals (1) more profound white matter involvement than that previously reported and (2) growth and shrinkage of cysts over time, which may suggest a more complex pathogenesis than that previously theorized.
Armstrong
Melissa J
MJ
Department of Neurology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA.
Hacein-Bey
Lotfi
L
Brown
Henry
H
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology*; D001927:Brain Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D002114:Calcinosis / Q000150:complications / Q000473:pathology*; D003072:Cognition Disorders / Q000150:complications; D003560:Cysts / Q000150:complications / Q000473:pathology*; D015140:Dementia, Vascular / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D018450:Disease Progression; D004401:Dysarthria / Q000150:complications; D004830:Epilepsy, Tonic-Clonic / Q000150:complications; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D018908:Muscle Weakness / Q000150:complications; D011859:Radiography; D035583:Rare Diseases