title: An efficient and economic asymmetric synthesis of (+)-nootkatone, tetrahydronootkatone, and derivatives.
abstract: A facile route to enantiomerically pure (+)-nootkatone and derivatives has been established through conjunctive stereoselective Grignard/anionic oxy-Cope (AOC) reactions.
authors.affiliation: Department of Chemistry, Louisiana State UniVersityAgricultural Center, Baton Rouge, Louisiana 70803, USA.
authors.forename: Anne M
authors.initials: AM
authors.lastname: Sauer
authors.forename: William E
authors.initials: WE
authors.lastname: Crowe
authors.forename: Gregg
authors.initials: G
authors.lastname: Henderson
authors.forename: Roger A
authors.initials: RA
authors.lastname: Laine
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C484718:tetrahydronootkatone; C050302:nootkatone