[Application of dynamic contrast enhancement MRI and post-processing technique for diagnosis of breast cancer].
OBJECTIVE
Magnetic resonance imaging (MRI), an advanced non-invasive technique, is regarded as one of the potential modalities in the diagnosis of breast cancer. This study was to investigate the application of dynamic contrast enhancement MRI and 3D reconstruction images in diagnosing breast tumors.


METHODS
From May 2006 to September 2007, 30 patients with breast diseases were scanned with MRI in Sun Yat-sen University Cancer Center. MR plain scans, dynamic contrast enhancement scans were performed, and 3D reconstruction images were obtained. The normal breast tissue was used as control, and the maximum slope ratio was calculated.


RESULTS
Forty-nine lesions were found in 30 patients, with an accuracy rate of 93.3%.


CONCLUSIONS
MRI scan is an effective and specific modality for the diagnosis of breast diseases with high sensitivity and accuracy. Dynamic contrast enhancement MRI, image subtraction, time-signal intensity curve, 3D reconstruction images and the maximum slope ratio are helpful to make the correct diagnosis of breast lesions.
Peng
Kang-Qiang
KQ
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, China.
Huang
Zi-Lin
ZL
Xie
Chuan-Miao
CM
Chen
Lin
L
Ouyang
Yi
Y
Zheng
Qing-Sheng
QS
Zhang
Yan
Y
He
Hao-Qiang
HQ
Wu
Pei-Hong
PH
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013382:Subtraction Technique