[Secondary hypopituitarism due to hypothalamic metastasis from small cell lung cancer].
Parasellar and hypothalamic metastases are uncommon. Their principal clinical manifestation is diabetes insipidus. Associated hypopituitarism is very rare. We report the case of a 54-year-old man with small cell lung cancer and hypopituitarism. A brain magnetic resonance imaging scan revealed a mass in the anterior region of the third ventricle with no clear etiology. The patient began chemotherapy treatment and the mass disappeared, which confirmed the diagnosis of secondary hypopituitarism caused by hypothalamic metastasis from small cell lung cancer.
Guerra Alía
Eva María
EM
Servicio de Oncología Médica. Hospital Universitario Ramón y Cajal. Madrid. España. eva_m_guerra@hotmail.com
Garrido López
Pilar
P
Pachón Olmos
Vanesa
V
Medina Martínez
Javier
J
González Martín
Antonio
A
Vaz Salgado
María Angeles
MA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D006261:Headache / Q000209:etiology; D020249:Hormone Replacement Therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000188:drug therapy / Q000209:etiology*; D007029:Hypothalamic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013974:Thyroxine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D013974:Thyroxine; D006854:Hydrocortisone