title: A new labdane diterpene from Vitex cauliflora Moldenke from the Madagascar rainforest.
abstract: Fractionation of an antiplasmodial ethanolic extract from the aerial parts of Vitex cauliflora led to the isolation of the new labdane diterpene 1 together with the known triterpene uvaol. The structure of the new compound 1 was established as 3-oxo,15,17,18-triacetoxy-labda-7,13E-diene on the basis of spectroscopic data (1D and 2D NMR, MS).
authors.affiliation: Centre National d'Application des Recherches Pharmaceutiques, B.P. 702, Antananarivo 101, Madagascar.
authors.forename: Vincent E
authors.initials: VE
authors.lastname: Rasamison
authors.forename: Leon
authors.initials: L
authors.lastname: Ranaivo-Harimanana
authors.forename: Shugeng
authors.initials: S
authors.lastname: Cao
authors.forename: Ende
authors.initials: E
authors.lastname: Pan
authors.forename: Fidy
authors.initials: F
authors.lastname: Ratovoson
authors.forename: F
authors.initials: F
authors.lastname: Randriantafika
authors.forename: R
authors.initials: R
authors.lastname: Rakotondrajaona
authors.forename: Stephan
authors.initials: S
authors.lastname: Rakotonandrasana
authors.forename: Rabodo
authors.initials: R
authors.lastname: Andriantsiferana
authors.forename: David G I
authors.initials: DG
authors.lastname: Kingston
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008270:Madagascar; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010963:Plasmodium falciparum / Q000187:drug effects; D020950:Vitex / Q000737:chemistry*
chemical_list: D004224:Diterpenes