KI-catalyzed aminobromination of olefins with TsNH(2)-NBS combination.
An efficient KI-catalyzed aminobromination of olefins has been developed with good to excellent yields and high regio- and stereoselectivities under transition metal-free conditions. A series of olefins, including alpha,beta-unsaturated carbonyl compounds and simple olefins, was studied. The reaction was performed in CH(2)Cl(2) using KI as the catalyst and TsNH(2) and NBS as the nitrogen and bromine sources.
Wei
Jun-fa
JF
School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an, 710062, PR China. weijf@snnu.edu.cn
Zhang
Li-hui
LH
Chen
Zhan-guo
ZG
Shi
Xian-ying
XY
Cao
Jing-jing
JJ
D000475:Alkenes / Q000737:chemistry*; D001966:Bromine / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D054879:Halogenation; D012825:Silicon / Q000737:chemistry*
D000475:Alkenes; D001966:Bromine; D012825:Silicon