title: New on-bead near-infrared fluorophores and fluorescent sensor constructs.
abstract: The facile synthesis and photophysical characterization of new on-bead fluorophores and fluorescent sensors are described. The unique covalent immobilization strategy results in highly fluorescent beads with sharp emission profiles between 650 and 800 nm. Illustrative examples include imaging in an aqueous cellular environment and adaptation to include off/on sensing functionality, proven by a prototypical detection of gaseous HCl.
authors.affiliation: Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Aniello
authors.initials: A
authors.lastname: Palma
authors.forename: Mariusz
authors.initials: M
authors.lastname: Tasior
authors.forename: Daniel O
authors.initials: DO
authors.lastname: Frimannsson
authors.forename: Thanh Truc
authors.initials: TT
authors.lastname: Vu
authors.forename: Rachel
authors.initials: R
authors.lastname: Méallet-Renault
authors.forename: Donal F
authors.initials: DF
authors.lastname: O'Shea
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D019265:Spectroscopy, Near-Infrared
chemical_list: D005456:Fluorescent Dyes