Right ventricular function in ST elevation myocardial infarction: effect of reperfusion.
OBJECTIVE
To investigate right ventricle function in successfully reperfused ST elevated myocardial infarction (STEMI) and to compare reperfusion strategies.


METHODS
From January 2007 to August 2008, 33 patients with anterior myocardial infarction (MI) and 48 patients with non-anterior myocardial infarction were enrolled in this study. Patients were treated with thrombolytic therapy (TT) or primary percutanaeous coronary intervention (PPCI) (Primary intervention: 16 and 25 patients (anterior and non-anterior consecutively), thrombolytic therapy: 17 and 23 patients (anterior and non-anterior consecutively)). Right ventricle (RV) function was analyzed using tissue Doppler investigation (TDI) after 72 hr of successful reperfusion.


RESULTS
There was no difference in right ventricle function assessed by right ventricle TDI Tei index between the PPCI and TT group (0.39+/-0.20 vs. 0.39+/-0,17). RV TDI Tei index increased in anterior MI patients treated with either PPCI or TT compared with control group (0.39+/-0.11 vs. 0.27+/-0.16, P=0.015 and 0.43+/-0.18 vs. 0.27+/-0.16 , P= 0.014 respectively). RV TDI Tei index did not differ between non-anterior MI patients treated with either PPCI or TT and control group (0.38+/-0.23 vs. 0.27+/-0.16, and 0.37+/-0.16 vs. 0.27+/-0.16, respectively).


CONCLUSIONS
RV function deteriorated in STEMI compared with healthy controls. Contrary to the expectation, RV dysfunction was observed in anterior STEMI, but not in non anterior MI. There was no difference in RV function between the two treatment modalities.
Karakurt
Ozlem
O
Ministry of Health, Diskapi Yildirim Beyazit Research and Education Hospital, Department of Cardiology, Ankara, Turkey. ozlemkarakurt55@yahoo.com
Akdemir
Ramazan
R
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D000069059:Atorvastatin; D000077144:Clopidogrel; D005260:Female; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy*; D015425:Myocardial Reperfusion; D011758:Pyrroles / Q000627:therapeutic use; D013300:Streptokinase / Q000627:therapeutic use; D015912:Thrombolytic Therapy / Q000379:methods; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D016896:Treatment Outcome; D016278:Ventricular Function, Right / Q000187:drug effects
D000319:Adrenergic beta-Antagonists; D006538:Heptanoic Acids; D011758:Pyrroles; D000069059:Atorvastatin; D000077144:Clopidogrel; D013300:Streptokinase; D008790:Metoprolol; D013988:Ticlopidine