title: Two cases with progressive cystic leukoencephalopathy.
abstract: Leukoencephalopathies with cystic changes in the white matter on magnetic resonance imaging are aetiologically heterogeneous neurological disorders seen in children. A group of leukoencephalopathies characterised by white matter lesions progressing to multifocal cystic degeneration has been reported in various disorders, including mitochondrial enzyme deficiencies, leukodystrophies, and infectious processes. We report two patients with leukoencephalopathy showing progressive cystic changes on serial MRI, and magnetic resonance spectroscopy resembling progressive cavitating leukoencephalopathy.
authors.affiliation: Division of Child Neurology, Department of Neurology, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
authors.forename: Z
authors.initials: Z
authors.lastname: Yapici
authors.forename: G
authors.initials: G
authors.lastname: Benbir
authors.forename: S
authors.initials: S
authors.lastname: Saltik
authors.forename: L
authors.initials: L
authors.lastname: He
authors.forename: G K
authors.initials: GK
authors.lastname: Brown
authors.forename: R W
authors.initials: RW
authors.lastname: Taylor
authors.forename: A
authors.initials: A
authors.lastname: Dincer
authors.forename: S
authors.initials: S
authors.lastname: Naidu
authors.forename: C
authors.initials: C
authors.lastname: Yalcinkaya
mesh_terms: D002675:Child, Preschool; D003560:Cysts / Q000150:complications* / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods