title: No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome.
abstract: Restless legs syndrome is a common disorder that may interrupt sleep and has been reported to produce daytime fatigue and/or mood changes. This study assessed whether patients with RLS have more cognitive dysfunction and depression than individuals of the same age and education who do not have RLS. The study showed that older individuals with mild RLS for at least 1 year do not have cognitive dysfunction and are not depressed compared with a control group of similar age and education.
authors.affiliation: Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, USA. driverdunckley.erika@mayo.edu
authors.forename: Erika
authors.initials: E
authors.lastname: Driver-Dunckley
authors.forename: Donald
authors.initials: D
authors.lastname: Connor
authors.forename: Joe
authors.initials: J
authors.lastname: Hentz
authors.forename: Marwan
authors.initials: M
authors.lastname: Sabbagh
authors.forename: Nina
authors.initials: N
authors.lastname: Silverberg
authors.forename: Jose
authors.initials: J
authors.lastname: Hernandez
authors.forename: Linda
authors.initials: L
authors.lastname: Vedders
authors.forename: Virgilio Gerald
authors.initials: VG
authors.lastname: Evidente
authors.forename: Holly
authors.initials: H
authors.lastname: Shill
authors.forename: John
authors.initials: J
authors.lastname: Caviness
authors.forename: Charles
authors.initials: C
authors.lastname: Adler
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D006801:Humans; D009483:Neuropsychological Tests; D017286:Polysomnography; D011569:Psychiatric Status Rating Scales; D012148:Restless Legs Syndrome / Q000150:complications* / Q000188:drug therapy; D012720:Severity of Illness Index