title: [Pellucid marginal degeneration and corneal ulceration, associated with Sjögren syndrome].
abstract: METHODS
  two cases reported presented corneal topography with peripheral inferior corneal slimming (pachymetry), flattening of superior and central meridian, high astigmatism against the rule, corroborating clinical pellucid marginal degeneration prognosis. A rheumatologist and a dermatologist confirmed primary and secondary Sjögren's syndrome in each case.
  
  
  CONCLUSIONS
  In the cases studied, the pellucid marginal degeneration was presented with inferior corneal slimming, progressive irregular astigmatism and decreased visual acuity. However, the patients were treated for a long time only for dry eye. The association between pellucid marginal degeneration, primary Sjögren syndrome and secondary Sjögren syndrome has not been described. In the analyzed cases, both pathologies were observed and caused a bad prognosis because the treatment required is very difficult.
authors.affiliation: Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México, Mexico. ferffb@yahoo.es
authors.forename: Fernando
authors.initials: F
authors.lastname: Fernández-Barboza
authors.forename: Karla
authors.initials: K
authors.lastname: Verdiguel-Sotelo
authors.forename: Adriana
authors.initials: A
authors.lastname: Hernández-López
mesh_terms: D003316:Corneal Diseases / Q000209:etiology*; D003320:Corneal Ulcer / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications*