[Epidural butorphanol analgesia in elderly patients undergoing hip replacement].
OBJECTIVE
To evaluate the efficacy and safety of continuous epidural analgesia (CEA) with butorphanol in elderly patients undergoing hip replacement.


METHODS
Sixty patients scheduled for selective hip replacement were randomized into group B (n=30) to receive patient-controlled epidural analgesia (PCEA) with butorphanol and group M (n=30) to receive PCEA with morphine. Their pain distribution at 5 time points, postoperative global score and the adverse effects in 48 h were observed.


RESULTS
The pain distribution at the 5 time points or the global score for postoperative PCEA in 48 h showed no statistically significant difference between the two groups (P<0.05). Analgesia with butorphanol caused less adverse effects (respiratory depression, nausea and vomiting, itching and abdominal distension) than that with morphine (P<0.05).


CONCLUSIONS
CEA with butorphanol is safe and effective for the treatment of postoperative pain in elderly patients and causes less adverse effects than morphine.
Hu
Dong-Hua
DH
Department of Anesthesia, First Affiliated Hospital of Jinan University, Guangzhou 510630, China. hu.dong.hua.1002@163.com
Li
Ya-Lan
YL
Cai
Ming-Xue
MX
Zhang
Hui
H
Xiang
Ming-Fang
MF
Shuai
Bing
B
Nie
Cai
C
D000368:Aged; D000369:Aged, 80 and over; D015360:Analgesia, Epidural; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D002077:Butorphanol / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage / Q000627:therapeutic use; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*
D009020:Morphine; D002077:Butorphanol