First case of granulomatous amebic encephalitis caused by Acanthamoeba castellanii in Taiwan.
We report the first case of granulomatous amebic encephalitis caused by Acanthamoeba in a previously healthy farmer in Taiwan who fell into a ditch. The DNA amplicons of amebas identified by polymerase chain reaction in the cerebrospinal fluid specimen and the ditch water specimens were identical and shared strong homology with A. castellanii . He survived after treatment with amphotericin B, rifampin, and corticosteroids.
Sheng
Wang-Huei
WH
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. whsheng@ntu.edu.tw
Hung
Chien-Ching
CC
Huang
Huai-Hsuan
HH
Liang
Shih-Yu
SY
Cheng
Yu-Jen
YJ
Ji
Dar-Der
DD
Chang
Shan-Chwen
SC
D048248:Acanthamoeba castellanii / Q000235:genetics / Q000302:isolation & purification*; D000562:Amebiasis / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000473:pathology*; D000818:Animals; D016054:DNA, Protozoan / Q000235:genetics; D004660:Encephalitis / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000469:parasitology*; D006099:Granuloma / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000469:parasitology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D013624:Taiwan / Q000453:epidemiology
D016054:DNA, Protozoan