Fetal lung volume in fetuses with urinary tract malformations: comparison by 2D-, 3D-sonography and magnetic resonance imaging.
OBJECTIVE
To evaluate the concordance between two-dimensional ultrasonography (2DUS), three-dimensional ultrasonography (3DUS) and magnetic resonance imaging (MRI) in the assessment of lung volume in fetuses with urinary tract malformations (UTM).


METHODS
This was a cross-sectional study involving 12 pregnancies between 19 and 34 weeks, with various fetal UTM. Pulmonary volume was obtained by 2DUS using the following equation: total lung volume = [right lung antero-posterior diameter (X) x transverse diameter (Y) x cranial-caudal diameter x 0.152 + left lung (X1) x (Y1) x (Z1) x 0.167]. Pulmonary volume by 3DUS was obtained using the virtual organ computer-aided analysis (VOCAL) method with a 30 degrees (VOL30), 18 degrees (VOL18) and 12 degrees (VOL12) rotation. A fast sequence of transverse lung section was also obtained by MRI. The intraclass correlation coefficient was used to evaluate the correlation between the three methods. The paired student t-test was used to compare the means.


RESULTS
There was a strong correlation between the three methods, and the highest correlations were between MRI and VOL18 for the right (ICC = 0.913) and left (ICC = 0.947) lungs. A strong correlation was also found between the lung volumes obtained through MRI and VOL12 as well as VOL18 (p = 0.544 and 0.286, respectively). However, for the left lung there was only a correlation between MRI and VOL12 (p = 0.49).


CONCLUSIONS
There is a good concordance between 3DUS (VOL12) and MRI in the evaluation of lung volume in fetuses with UTM.
Araujo Júnior
Edward
E
Obstetrics Department of São Paulo Federal University (UNIFESP), São Paulo, São Paulo, Brazil. araujojred@terra.com.br
De Oliveira
Patrícia Soares
PS
Nardozza
Luciano Marcondes Machado
LM
Simioni
Christiane
C
Rolo
Liliam Cristine
LC
Goldman
Susan Menasce
SM
Szejnfeld
Jacob
J
Moron
Antonio Fernandes
AF
D003430:Cross-Sectional Studies; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000196:embryology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*; D014551:Urinary Tract / Q000002:abnormalities* / Q000196:embryology*