Superoxide interaction with nickel and iron superoxide dismutases.
Interaction of superoxide with the metal active sites of nickel and iron-containing superoxide dismutases is investigated with density functional theory. Outer-sphere mechanisms for both the reduction and oxidation of superoxide are proposed to be the common feature of these structurally unrelated SODs.
Silaghi-Dumitrescu
Radu
R
Department of Chemistry, Babes-Bolyai University, Cluj-Napoca RO-400028, Romania. rsilaghi@chem.ubbcluj.ro
D056004:Molecular Dynamics Simulation; D015394:Molecular Structure; D009532:Nickel / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000737:chemistry* / Q000378:metabolism*; D013481:Superoxides / Q000737:chemistry / Q000378:metabolism*
D013481:Superoxides; D009532:Nickel; D013482:Superoxide Dismutase