title: Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastases.
abstract: The objective of this study was to examine the agreement between health care professionals' (HCPs) and patients' evaluation of health-related quality of life (HRQOL) issues for cancer patients with bone metastases. A total of 413 patients and 152 HCPs were interviewed across five centres worldwide. Mean scores were almost always higher for HCPs than for patients. Patients and HCPs agreed that four issues affect HRQOL of bone metastases patients profoundly: 'long-term (chronic) pain', 'difficulty in carrying out usual daily tasks', 'able to perform self-care' and 'able to perform role functioning'. A substantial difference was found with respect to the perceived importance of psychosocial and somatic issues. Patients emphasised psychosocial issues with a particular focus on 'worry' about loss of mobility, dependence on others and disease progression, HCPs however rated 'symptom' issues as more important, specifically those related to 'pain'. In conclusion, patients and HCPs agreed that pain and physical/role functioning are important to the HRQOL of cancer patients with bone metastases, but patients also emphasized the importance of psychosocial issues to HRQOL. This information has been an important component in the development of a health-related quality of life questionnaire for patients with bone metastases (EORTC QLQ-BM 22).
authors.affiliation: Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.
authors.forename: Kristin
authors.initials: K
authors.lastname: Harris
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
authors.forename: Liying
authors.initials: L
authors.lastname: Zhang
authors.forename: Galina
authors.initials: G
authors.lastname: Velikova
authors.forename: Andrea
authors.initials: A
authors.lastname: Bezjak
authors.forename: Jackson
authors.initials: J
authors.lastname: Wu
authors.forename: Michael
authors.initials: M
authors.lastname: Barton
authors.forename: Orhan
authors.initials: O
authors.lastname: Sezer
authors.forename: Richard
authors.initials: R
authors.lastname: Eek
authors.forename: Jesmin
authors.initials: J
authors.lastname: Shafiq
authors.forename: Albert
authors.initials: A
authors.lastname: Yee
authors.forename: Mark
authors.initials: M
authors.lastname: Clemons
authors.forename: Michael
authors.initials: M
authors.lastname: Brundage
authors.forename: Peter
authors.initials: P
authors.lastname: Hoskin
authors.forename: Yvette
authors.initials: Y
authors.lastname: van der Linden
authors.forename: Colin D
authors.initials: CD
authors.lastname: Johnson
authors.forename: Andrew
authors.initials: A
authors.lastname: Bottomley
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001291:Attitude of Health Personnel; D001294:Attitude to Health; D001315:Australia; D001859:Bone Neoplasms / Q000523:psychology* / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology; D002170:Canada; D002908:Chronic Disease; D005260:Female; D005858:Germany; D006282:Health Personnel / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology; D010146:Pain / Q000523:psychology; D011471:Prostatic Neoplasms / Q000473:pathology; D011788:Quality of Life / Q000523:psychology*; D012648:Self Care / Q000523:psychology; D011795:Surveys and Questionnaires