title: Developmental biology: Pipe's smoking guns.
abstract: The formation of the dorso-ventral body pattern of Drosophila involves the restricted activation of a serine protease cascade in the extracellular space between the egg shell and the embryo. Now, the first molecular links have been identified between ventral gene expression during oogenesis and the activation of the protease cascade in the early embryo.
authors.affiliation: HHMI/Dept. of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. schupbac@princeton.edu
authors.forename: Trudi
authors.initials: T
authors.lastname: Schüpbach
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000502:physiology; D004330:Drosophila / Q000196:embryology; D005110:Extracellular Space / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D012697:Serine Endopeptidases / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
chemical_list: D012697:Serine Endopeptidases