title: A case of melanotic desmoplastic ganglioglioma.
abstract: We describe a case of desmoplastic infantile ganglioglioma (DIG) in a 9-month-old boy located in the temporal lobe. Grossly the tumor was brown and superficially located. Histologically the tumor contained pigment in numerous neoplastic cells, shown to be melanosomal melanin by ultrastructural examination. Pigmented neoplasms have been reported at various sites in the central and peripheral nervous system. Previous reports on pigmented neuroepithelial tumors include neoplasms containing melanin, while others have contained neuromelanin and or lipofuscin. This case represents the first description of pigmented neoplastic cells in DIG, enlarging the spectrum of pigmented primary CNS tumors.
authors.affiliation: Departement of Pathology, University La Sapienza, Rome, Italy. manila_antonelli@yahoo.it
authors.forename: Manila
authors.initials: M
authors.lastname: Antonelli
authors.forename: Stefania
authors.initials: S
authors.lastname: Acerno
authors.forename: Cristina
authors.initials: C
authors.lastname: Baldoli
authors.forename: Maria Rosaria
authors.initials: MR
authors.lastname: Terreni
authors.forename: Felice
authors.initials: F
authors.lastname: Giangaspero
mesh_terms: D001932:Brain Neoplasms / Q000378:metabolism* / Q000473:pathology* / Q000648:ultrastructure; D005500:Follow-Up Studies; D018303:Ganglioglioma / Q000378:metabolism* / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008543:Melanins / Q000378:metabolism*; D013702:Temporal Lobe / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure
chemical_list: D008543:Melanins