[Expression of microRNAs in endometrioid adenocarcinoma].
OBJECTIVE
To analyze miRNA expression profile of endometrioid adenocarcinoma.


METHODS
Collect Endometrium was collected from cancer and park cancer tissue. And the total RNA was extracted. The microarray detection system was employed to analyze whether there was difference in microRNA expression between cancer tissue and park cancer tissue.


RESULTS
A total of 111 differentially expressed miRNA were found, including 68 over-expression miRNA and 43 low-expression.


CONCLUSIONS
MiRNA may play important roles in tumorigenesis of endometrioid adenocarcinoma. The study of miRNA contributes to elucidate the molecular mechanism of endometrial cancer.
Liu
Xia
X
Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.
Xia
Wei
W
Dai
Yin-mei
YM
Shao
Ning-sheng
NS
Zhang
Wei-yuan
WY
D018269:Carcinoma, Endometrioid / Q000378:metabolism* / Q000473:pathology; D016889:Endometrial Neoplasms / Q000378:metabolism* / Q000473:pathology; D055354:Exosomes; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis
D035683:MicroRNAs