title: Direct synthesis of highly substituted thiophenes through copper(i)-catalyzed tandem reactions of alkylidenethiiranes with terminal alkynes.
abstract: A novel copper(i)-catalyzed tandem addition/cycloisomerization reaction of 1-phenylsulfonylalkylidenethiiranes with terminal alkynes for the convergent assembly of 2-(alpha-phenylsulfonylalkyl)-thiophenes is reported, which could directly assemble various functional groups incorporated into the thiophene ring.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou, China.
authors.forename: Yiping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Bian
authors.forename: Weijun
authors.initials: W
authors.lastname: Yao
authors.forename: Jianming
authors.initials: J
authors.lastname: Gu
authors.forename: Cheng
authors.initials: C
authors.lastname: Ma
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D007536:Isomerism; D015394:Molecular Structure; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D000480:Alkynes; D013876:Thiophenes; D003300:Copper