title: Results of four inter-laboratory comparisons provided by the Forensic Isotope Ratio Mass Spectrometry (FIRMS) network.
abstract: Between 2004 and 2008 the Forensic Isotope Ratio Mass Spectrometry (FIRMS) network organised four Inter-Laboratory Camparison excercises with the aim of harmonising and validating isotopic measurements to be used for forensic applications. The samples distributed comprised materials of potential forensic interest such as packaging and pharmaceuticals to be analysed for delta2H, delta13C, delta15N and delta18O composition. As many as 30 international laboratories participated in these comparisons. Results have shown overall improvements for both within- and inter-laboratory reproducibility with respect to delta13C and delta15N measurements. Only a small number of laboratories returned results for delta2H and delta18O analysis and these results highlighted a need for improvement in the reproducibility of these measurements and a need to address the exchange of hydrogen between samples and ambient moisture. Results also highlighted the importance of sample preparation procedures and the need to standardise both these procedures and calibration against Standard Reference Materials. Future Inter-laboratory Comparison exercises will assess the suitability of laboratories to submit data to national and international databases similar to those currently operated for fingerprints, DNA etc.
authors.affiliation: Mass Spec Analytical Ltd, Building 20F, Golf Course Lane, Filton, Bristol BS99 7AR, United Kingdom. jimc@msaltd.co.uk
authors.forename: James F
authors.initials: JF
authors.lastname: Carter
authors.forename: Jenny C
authors.initials: JC
authors.lastname: Hill
authors.forename: Sean
authors.initials: S
authors.lastname: Doyle
authors.forename: Claire
authors.initials: C
authors.lastname: Lock
mesh_terms: D002247:Carbon Isotopes; D044707:Forensic Sciences / Q000379:methods*; D006859:Hydrogen; D007554:Isotopes / Q000032:analysis; D007753:Laboratories / Q000592:standards*; D013058:Mass Spectrometry / Q000379:methods*; D009587:Nitrogen Isotopes; D010103:Oxygen Isotopes; D012015:Reference Standards; D015203:Reproducibility of Results
chemical_list: D002247:Carbon Isotopes; D007554:Isotopes; D009587:Nitrogen Isotopes; D010103:Oxygen Isotopes; D006859:Hydrogen