[Pathogenicity of the opportunistic pathogenic fungus Cryptococcus neoformans--a review].
The increase of clinical fungal infection causes a wide awareness. Cryptococcus neoformans is one of the major fungal pathogens. In the past 10 years,much progress has been made in its molecular biological research, including the synthesis and mobilization of the virulence factors as well as the signal transduction pathways during pathogeny. All these will help prevent or treat this fungus. We review the virulence factors and the molecular biological research progress.
Jiang
Nan
N
Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China. jiangnan82@yahoo.cn
Zhang
Defa
D
Yan
Bing
B
Pan
Jiao
J
Zhu
Xudong
X
D003455:Cryptococcus neoformans / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*; D000242:Cyclic AMP / Q000378:metabolism / Q000502:physiology; D015966:Gene Expression Regulation, Fungal / Q000235:genetics / Q000502:physiology; D042845:Laccase / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism / Q000502:physiology; D008954:Models, Biological; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D037521:Virulence Factors / Q000235:genetics / Q000378:metabolism / Q000502:physiology
D037521:Virulence Factors; D000242:Cyclic AMP; D042845:Laccase; D020928:Mitogen-Activated Protein Kinases