title: [Pathogenicity of the opportunistic pathogenic fungus Cryptococcus neoformans--a review].
abstract: The increase of clinical fungal infection causes a wide awareness. Cryptococcus neoformans is one of the major fungal pathogens. In the past 10 years,much progress has been made in its molecular biological research, including the synthesis and mobilization of the virulence factors as well as the signal transduction pathways during pathogeny. All these will help prevent or treat this fungus. We review the virulence factors and the molecular biological research progress.
authors.affiliation: Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China. jiangnan82@yahoo.cn
authors.forename: Nan
authors.initials: N
authors.lastname: Jiang
authors.forename: Defa
authors.initials: D
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Yan
authors.forename: Jiao
authors.initials: J
authors.lastname: Pan
authors.forename: Xudong
authors.initials: X
authors.lastname: Zhu
mesh_terms: D003455:Cryptococcus neoformans / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*; D000242:Cyclic AMP / Q000378:metabolism / Q000502:physiology; D015966:Gene Expression Regulation, Fungal / Q000235:genetics / Q000502:physiology; D042845:Laccase / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism / Q000502:physiology; D008954:Models, Biological; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D037521:Virulence Factors / Q000235:genetics / Q000378:metabolism / Q000502:physiology
chemical_list: D037521:Virulence Factors; D000242:Cyclic AMP; D042845:Laccase; D020928:Mitogen-Activated Protein Kinases