title: Nanoreactors for pH controlled sequential activity switching in multistep enzymatic processes.
abstract: This theoretical model predicts that the activity of multiple enzymes may be controlled simultaneously with superior efficiency in nanosized reactors by adjusting pH. Multistep enzymatic processes employed for various purposes including organic biotransformation may require application of multiple reactions and isolation of intermediates. Sequential activity switching would offer substantial advantages. Nanoreactors would provide better option to fully appreciate the pH switching approach.
authors.affiliation: University of Dhaka, Department of Genetic Engineering and Biotechnology, Dhaka, Bangladesh. minhazuddean@gmail.com
authors.forename: S M
authors.initials: SM
authors.lastname: Minhaz Ud-Dean
mesh_terms: D000465:Algorithms; D019149:Bioreactors; D002021:Buffers; D004798:Enzymes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D053858:Metabolic Networks and Pathways; D008956:Models, Chemical; D009097:Multienzyme Complexes / Q000378:metabolism*; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D013379:Substrate Specificity
chemical_list: D002021:Buffers; D004798:Enzymes; D009097:Multienzyme Complexes