[The influence of ecological factors of Polesky State Radioecological Reserve on spontaneous and chemically induced mutagenesis and tumor formation].
The cycle of researches of the influence of an exposion of mice of line Af in the conditions of the zone of Chernobyl disaster on spontaneous and chemically induced mutability, lung tumour (adenomas), morphological and functional condition of alveolar macrophages, and also genetic effects in natural populations wild rodents is executed. The increase in polychromatic frequency in mouse bone marrow, adenomas in lungs, and change of sensitivity of an organism to action mutagen and transgenerational transfer of genetic damages is shown.
Malenchenko
A F
AF
Konoplia
E F
EF
Sushko
S N
SN
Savin
A O
AO
Kadukova
E M
EM
Goncharov
S V
SV
D000236:Adenoma / Q000235:genetics / Q000473:pathology; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects / Q000235:genetics* / Q000473:pathology; D047852:Chernobyl Nuclear Accident; D004463:Ecology; D004913:Erythrocytes, Abnormal / Q000528:radiation effects; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology; D016676:Macrophages, Alveolar / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D051379:Mice; D008815:Mice, Inbred Strains; D016296:Mutagenesis / Q000528:radiation effects*; D009153:Mutagens / Q000633:toxicity; D009381:Neoplasms, Radiation-Induced / Q000235:genetics* / Q000473:pathology; D011833:Radiation Injuries, Experimental / Q000235:genetics* / Q000473:pathology; D002094:Republic of Belarus
D009153:Mutagens