Extensively drug-resistant tuberculosis: a new face to an old pathogen.
The presence and consequences of resistance to drugs used for the treatment of tuberculosis have long been neglected. The recent detection and recognition of widespread multiple-drug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis have raised interest and concern among clinicians and public health authorities globally. In this article, we describe the current global status of drug-resistant tuberculosis. We discuss the development of resistance, current management, and strategies for control.
Shenoi
Sheela
S
Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut 06510-8002, USA. sheela.shenoi@yale.edu
Friedland
Gerald
G
D054908:Extensively Drug-Resistant Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D012307:Risk Factors