title: Spread of infection to Virchow-Robin spaces in a patient with Streptococcus pneumoniae meningitis.
abstract: We present a case of a child with acute bacterial leptomeningeal infection caused by Streptococcus pneumoniae. There was an extension of infection along multiple Virchow-Robin spaces into the brain parenchyma, resulting in multiple microabscesses. These abscesses showed restricted diffusion on the diffusion-weighted images on the initial magnetic resonance imaging. A follow-up magnetic resonance imaging showed evolution of these microabscesses with contrast enhancement that ultimately resolved with antibiotics.
authors.affiliation: Division of Neuroradiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Gordon
authors.forename: Hemant
authors.initials: H
authors.lastname: Parmar
authors.forename: Mohannad
authors.initials: M
authors.lastname: Ibrahim
mesh_terms: D000293:Adolescent; D001921:Brain / Q000098:blood supply / Q000382:microbiology / Q000473:pathology; D001922:Brain Abscess / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D001927:Brain Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D005334:Fever / Q000209:etiology; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008586:Meningitis, Pneumococcal / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D014839:Vomiting / Q000209:etiology
chemical_list: D003287:Contrast Media