Brain factor-7 extracted from Bombyx mori enhances cognition and attention in normal children.
It has been reported that brain factor-7 (BF-7) extracted from Bombyx mori improves cognitive functions in normal juveniles and adults as well as cognitively impaired patients. Clinical studies with normal children evaluated the role of BF-7 on brain function in these patients. The objective of this study was to improve cognitive functions of normal schoolchildren with BF-7. Forty-six normal healthy children were divided into two treatment groups: BF-7 (9.9 +/- 1.18 years old; 9 boys, 14 girls) and placebo (9.8 +/- 1.03 years old; 10 boys, 13 girls). The Color Trails Making Test was used to measure the efficacy of BF-7 on cognition and attention. Results showed that BF-7 reduced the response time by an average of 23% for the Color Trails Making Test. Moreover, BF-7 improved the accuracy of the task around twofold. The results reveal that BF-7 improves brain function for attention and cognitive flexibility in children.
Kim
Kunwoo
K
Department of Psychiatry, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea.
Park
Subin
S
Yoo
Hanik K
HK
Lee
Jun-Young
JY
Jung
Hee-Yeon
HY
Kim
Do-Hee
DH
Lee
Hyun-Jung
HJ
Kim
Jin-Young
JY
Youn
Young-Chul
YC
Marshall
Maurice R
MR
Kim
Sung-Su
SS
Jeong
Yoonhwa
Y
D000818:Animals; D001288:Attention / Q000187:drug effects*; D012831:Bombyx / Q000737:chemistry; D002648:Child; D003071:Cognition / Q000187:drug effects*; D005260:Female; D006801:Humans; D019476:Insect Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D009419:Nerve Tissue Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D018697:Nootropic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D011930:Reaction Time; D012016:Reference Values; D014145:Trail Making Test
D019476:Insect Proteins; D009419:Nerve Tissue Proteins; D018697:Nootropic Agents