A complete backbone spectral assignment of human apolipoprotein AI on a 38 kDa prebetaHDL (Lp1-AI) particle.
ApoAI is the major protein component of the high-density lipoprotein (HDL) that has been a hot subject of interests because of its anti-atherogenic properties. ApoAI/prebeta-HDL is the most effective acceptors specifically for free cholesterol in human plasma and serves as the precursor of HDL particles. Here we report a complete backbone assignment of human apoAI on a 38 kDa prebetaHDL (Lp1-AI) particle.
Ren
Xuefeng
X
Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Yang
Yunhuang
Y
Neville
Tracey
T
Hoyt
David
D
Sparks
Daniel
D
Wang
Jianjun
J
D016632:Apolipoprotein A-I / Q000737:chemistry* / Q000235:genetics; D053442:High-Density Lipoproteins, Pre-beta / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D015394:Molecular Structure; D008970:Molecular Weight; D046912:Multiprotein Complexes / Q000737:chemistry / Q000235:genetics; D019906:Nuclear Magnetic Resonance, Biomolecular; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics
D016632:Apolipoprotein A-I; D053442:High-Density Lipoproteins, Pre-beta; D046912:Multiprotein Complexes; D011994:Recombinant Proteins