title: Premature ovarian failure among hairdressers.
abstract: BACKGROUND
  Hairdressers constitute a major occupational group of female workers who are exposed to chemicals that cause reproductive abnormalities in animal models. The purpose of this study was to examine whether hairdressers are at increased risk of premature ovarian failure (POF) compared with women of similar age in other occupations.
  
  
  METHODS
  This study analyzed data from a population-based sample of 443 hairdressers and 508 women in other occupations, who responded to a mailed survey. POF was assessed in all eligible participants by self-report of a doctor's diagnosis.
  
  
  RESULTS
  Among 443 hairdressers and 508 women in other occupations, 14 (3.2%) and 7 (1.4%) developed POF, respectively. A non-significant increase in the risk of POF was observed among hairdressers compared with non-hairdressers (adjusted relative risk (RR) 1.90; 95% confidence interval (CI) 0.76, 4.72). When limited to Caucasian women only (approximately 85% of respondents), the increased risk was statistically significant (RR 3.24; 95% CI 1.06, 9.91). Among Caucasian women of 40-55 years of age, hairdressers were more than five times as likely to report POF compared with non-hairdressers (RR 5.58; 95% CI 1.24, 25.22).
  
  
  CONCLUSIONS
  Hairdressers may be at increased risk for POF compared with women employed in other occupations.
authors.affiliation: The Prevention and Research Center, The Weinberg Center for Women's Health & Medicine, Mercy Medical Center, Baltimore, MD 21202, USA.
authors.forename: L
authors.initials: L
authors.lastname: Gallicchio
authors.forename: S
authors.initials: S
authors.lastname: Miller
authors.forename: T
authors.initials: T
authors.lastname: Greene
authors.forename: H
authors.initials: H
authors.lastname: Zacur
authors.forename: J A
authors.initials: JA
authors.lastname: Flaws
mesh_terms: D000328:Adult; D005260:Female; D006203:Hair Preparations / Q000633:toxicity*; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure; D016649:Primary Ovarian Insufficiency / Q000453:epidemiology*; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D006203:Hair Preparations