title: Community effect of Haemophilus influenzae type b vaccination in India.
abstract: We assessed the effect of distribution of Haemophilus influenzae type b (Hib) vaccine in the private health care sector on Hib meningitis admissions at a referral hospital in India. The annual mean number of Hib cases was 10.7 before Hib vaccine introduction, falling to 3.8 cases following introduction (P < 0.0001). By contrast, the mean of annual numbers of pneumococcal cases were 3.0 and 4.6, (P = 0.55). Even at relatively low coverage through private sector distribution, Hib vaccine has significant community impact on Hib disease.
authors.affiliation: Department of Child Health, Christian Medical College, Vellore, India. valsan@cmcvellore.ac.in
authors.forename: Valsan Philip
authors.initials: VP
authors.lastname: Verghese
authors.forename: Ingrid K
authors.initials: IK
authors.lastname: Friberg
authors.forename: Thomas
authors.initials: T
authors.lastname: Cherian
authors.forename: Palany
authors.initials: P
authors.lastname: Raghupathy
authors.forename: V
authors.initials: V
authors.lastname: Balaji
authors.forename: M K
authors.initials: MK
authors.lastname: Lalitha
authors.forename: Kurien
authors.initials: K
authors.lastname: Thomas
authors.forename: T Jacob
authors.initials: TJ
authors.lastname: John
authors.forename: Mark C
authors.initials: MC
authors.lastname: Steinhoff
mesh_terms: D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000276:immunology; D019741:Haemophilus influenzae type b / Q000276:immunology*; D006801:Humans; D007194:India / Q000453:epidemiology; D032541:Mass Vaccination; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000276:immunology* / Q000517:prevention & control; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D016012:Poisson Distribution; D011159:Population Surveillance; D011446:Prospective Studies; D012044:Regression Analysis; D013296:Streptococcus pneumoniae / Q000276:immunology
chemical_list: D018073:Haemophilus Vaccines