title: CarD tricks and magic spots: mechanisms of stringent control in mycobacteria.
abstract: Global reprogramming of bacterial gene expression in response to nutritional stress, the stringent response, is well studied in E. coli. Now Stallings et al. report that Mycobacterium tuberculosis employs a different strategy involving the general transcription factor CarD for growth control and persistence in response to stresses encountered during infection.
authors.affiliation: Department of Microbiology and Immunology, Program in Microbial Pathogenesis and Host Defense, University of California, San Francisco, San Francisco, CA 94143, USA.
authors.forename: Lynn E
authors.initials: LE
authors.lastname: Connolly
authors.forename: Jeffery S
authors.initials: JS
authors.lastname: Cox
mesh_terms: D015964:Gene Expression Regulation, Bacterial; D009169:Mycobacterium tuberculosis / Q000378:metabolism / Q000502:physiology*; D013312:Stress, Physiological; D014157:Transcription Factors / Q000502:physiology*
chemical_list: D014157:Transcription Factors