title: [Secondary hypopituitarism due to hypothalamic metastasis from small cell lung cancer].
abstract: Parasellar and hypothalamic metastases are uncommon. Their principal clinical manifestation is diabetes insipidus. Associated hypopituitarism is very rare. We report the case of a 54-year-old man with small cell lung cancer and hypopituitarism. A brain magnetic resonance imaging scan revealed a mass in the anterior region of the third ventricle with no clear etiology. The patient began chemotherapy treatment and the mass disappeared, which confirmed the diagnosis of secondary hypopituitarism caused by hypothalamic metastasis from small cell lung cancer.
authors.affiliation: Servicio de Oncología Médica. Hospital Universitario Ramón y Cajal. Madrid. España. eva_m_guerra@hotmail.com
authors.forename: Eva María
authors.initials: EM
authors.lastname: Guerra Alía
authors.forename: Pilar
authors.initials: P
authors.lastname: Garrido López
authors.forename: Vanesa
authors.initials: V
authors.lastname: Pachón Olmos
authors.forename: Javier
authors.initials: J
authors.lastname: Medina Martínez
authors.forename: Antonio
authors.initials: A
authors.lastname: González Martín
authors.forename: María Angeles
authors.initials: MA
authors.lastname: Vaz Salgado
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D006261:Headache / Q000209:etiology; D020249:Hormone Replacement Therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000188:drug therapy / Q000209:etiology*; D007029:Hypothalamic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013974:Thyroxine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D013974:Thyroxine; D006854:Hydrocortisone