Outcome and prognostic factors in the conservative treatment of breast cancer.
BACKGROUND
The aim of this retrospective study is to evaluate the results and identify prognostic factors in early breast cancer.


METHODS
One hundred breast cancers, 79 stage I and 21 stage II, had a conservative treatment between September 1993 and February 1996. Median age was 57 years; median tumor size 15 mm. Pathology was infiltrating ductal carcinoma in 88%. All patients underwent a conservative surgery followed by external radiotherapy. Twenty-eight patients received adjuvant chemotherapy and 64 patients received hormonal therapy. The median follow-up was 100 months.


RESULTS
The 10 years overall survival rate was 85% and the metastasis free survival rate was 88.5%. The 10 years local control rate was 85.7%. Women less than 45 years old had a worse prognosis.


CONCLUSIONS
These high rates of survival and local control confirm that breast conservation therapy yields favorable results, and that age is a major risk factor in women with early breast cancer.
Nasr
Elie
E
*Radiation Oncology Department, Hôtel-Dieu de France, University Hospital, Beirut, Lebanon. nasre@inco.com.lb
Nasr
Dolly
D
Azoury
Fares
F
Fares
Georges
G
D000328:Adult; D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome