title: [Effects of bicarbonated Ringer's solution for infants and children undergoing open-heart surgery].
abstract: BACKGROUND
  There is no study on the use of bicarbonated Ringer's solution (BR) for pediatric patients. We evaluated the effect of BR on infants and children undergoing open-heart surgery, compared with acetated Ringer's solution (AR).
  
  
  METHODS
  The records of 18 pediatric patients with congenital heart disease who had undergone elective open-heart surgeries with cardiopulmonary bypass (CPB) were reviewed retrospectively. Eight patients received AR as infusion and CPB priming solution, and ten patients received BR. The pH, HCO3-, base excess and lactate were measured at seven points ; (1) after anesthesia induction, (2) CPB-start, (3) before CPB withdrawal or 60-minute after CPB, (4) after CPB withdrawal, (5) end of operation, (6) 6-hour after operation, and (7) 24-hour after operation, and administered volume of sodium bicarbonate during surgery and 24-hour after surgery were evaluated. Data were compared between two groups.
  
  
  RESULTS
  There were no significant differences in values of pH, HCO3-, base excess and lactate between the two groups at any measurement point. The administered volume of sodium bicarbonate during the procedure in BR was significantly smaller than that in AR.
  
  
  CONCLUSIONS
  BR was useful as infusion fluid and CPB priming solution for infants and children who underwent open-heart surgeries, and reduced the administration of sodium bicarbonate during surgery.
authors.affiliation: Department of Anesthesiology, Osaka Medical College, Takatsuki 569-8686.
authors.forename: Maiko
authors.initials: M
authors.lastname: Asano
authors.forename: Yumi
authors.initials: Y
authors.lastname: Doi
authors.forename: Masako
authors.initials: M
authors.lastname: Soen
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Minami
mesh_terms: D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002675:Child, Preschool; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D007223:Infant; D007552:Isotonic Solutions; D008297:Male; D012189:Retrospective Studies; D017693:Sodium Bicarbonate / Q000008:administration & dosage
chemical_list: D007552:Isotonic Solutions; C028570:Ringer's acetate; C506920:bicarbonated Ringer's solution; D017693:Sodium Bicarbonate