New on-bead near-infrared fluorophores and fluorescent sensor constructs.
The facile synthesis and photophysical characterization of new on-bead fluorophores and fluorescent sensors are described. The unique covalent immobilization strategy results in highly fluorescent beads with sharp emission profiles between 650 and 800 nm. Illustrative examples include imaging in an aqueous cellular environment and adaptation to include off/on sensing functionality, proven by a prototypical detection of gaseous HCl.
Palma
Aniello
A
Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Tasior
Mariusz
M
Frimannsson
Daniel O
DO
Vu
Thanh Truc
TT
Méallet-Renault
Rachel
R
O'Shea
Donal F
DF
D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D019265:Spectroscopy, Near-Infrared
D005456:Fluorescent Dyes