Circulatory response and autonomic nervous activity during gum chewing.
Mastication has been proven to enhance the systemic circulation, with circulatory responses seeming to be largely regulated by autonomic nervous activity via a more complex regulatory system than those of other activities. However, few studies have examined the relationships between changes in autonomic nervous activity and the systemic circulation that are induced by masticatory movement. We investigated changes in the systemic circulation and autonomic nervous activity during gum chewing to clarify the influence of mastication. Electrocardiograms, arterial blood pressure, and masseter electromyograms were taken while chewing gum continuously as indicators of systemic circulation in 10 healthy subjects with normal dentition. Cardiac sympathetic activity and vagus nervous activity, as well as vasomotor sympathetic nervous activity, were evaluated by fluctuation analysis of heart rate and blood pressure. Repeated analysis of variance and multiple comparisons were performed to determine chronological changes in each indicator during gum chewing. Gum chewing increased the heart rate and the mean arterial pressure. Although cardiac sympathetic activity and vagus nervous activity showed significant changes, vasomotor sympathetic nervous activity did not. These results suggest that changes in the autonomic nervous activity of the heart are mainly involved in the enhancement of systemic circulation with gum chewing. This explains some characteristics of autonomic nervous regulation in masticatory movement.
Hasegawa
Yoko
Y
Division of Oromaxillofacial Regeneration, Course of Integrated Oral Science, Osaka University Graduate School of Dentistry, Yamada-oka, Suita, Osaka, Japan.
Sakagami
Joe
J
Ono
Takahiro
T
Hori
Kazuhiro
K
Zhang
Min
M
Maeda
Yoshinobu
Y
D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D001775:Blood Circulation / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D002638:Chewing Gum; D004562:Electrocardiography; D004576:Electromyography; D005260:Female; D006329:Heart Conduction System / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008406:Masseter Muscle / Q000502:physiology; D008409:Mastication / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D013997:Time Factors; D014630:Vagus Nerve / Q000502:physiology; D014666:Vasomotor System / Q000502:physiology
D002638:Chewing Gum