Coronary artery dilatation in Incomplete Kawasaki disease.
We conducted this study to compare the incidence of coronary artery dilatation in children with Incomplete and Classical Kawasaki disease, diagnosed as per AHA criteria. Subjects were included on a retrospective review of records (2002-2007); those with a discharge diagnosis of Kawasaki disease were enrolled. A total of 29 patients were identified (3.1 per 1000 pediatric admissions), out of which 22 were boys (median age: 4.8 years; range: 4 months-11 years). Seventeen (58.6%) had Classical KD and twelve (41.4%) children had Incomplete KD. All children received IVIG and underwent echocardiography. Coronary involvement was more in Incomplete KD (11/12 = 91.6%) as compared to Classical KD (7/17= 41.1%). The sensitivity, specificity and predictive value of AHA criteria to detect coronary artery dilatation was 39%, 9%, and 41%, respectively. We conclude that children presenting with Incomplete Kawasaki disease are at a higher risk of coronary artery abnormalities.
Vijayan
A P
AP
Department of Pediatrics, Malabar Institute of Medical Sciences, Calicut 673 016, Kerala, India. drvijayan.ap@gmail.com
Dinesh
K B
KB
Nath
K R Divia
KR
D002648:Child; D002675:Child, Preschool; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000473:pathology*; D004108:Dilatation, Pathologic / Q000473:pathology; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology* / Q000473:pathology*; D012720:Severity of Illness Index