title: Assignment of backbone (1)H, (13)C and (15)N resonances of human IgG1 Fc (51.4 kDa).
abstract: Here we report the NMR resonance assignments for the Fc region of human IgG1 expressed in E. coli, a 51.4 kDa dimer in solution (residues 221-447). The assignments have been deposited in the BioMagResBank with a BMRB accession number of 15514.
authors.affiliation: Department of Pharmaceutics, Amgen Inc, Thousand Oaks, CA 91320, USA. liud@amgen.com
authors.forename: Dingjiang
authors.initials: D
authors.lastname: Liu
authors.forename: Melanie J
authors.initials: MJ
authors.lastname: Cocco
authors.forename: Robert
authors.initials: R
authors.lastname: Rosenfied
authors.forename: Jeffery K
authors.initials: JK
authors.lastname: Lewis
authors.forename: Da
authors.initials: D
authors.lastname: Ren
authors.forename: Luke
authors.initials: L
authors.lastname: Li
authors.forename: Richard L
authors.initials: RL
authors.lastname: Remmele
authors.forename: David N
authors.initials: DN
authors.lastname: Brems
mesh_terms: D000595:Amino Acid Sequence; D002247:Carbon Isotopes / Q000737:chemistry; D002352:Carrier Proteins / Q000737:chemistry*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D017434:Protein Structure, Tertiary; D011522:Protons
chemical_list: D002247:Carbon Isotopes; D002352:Carrier Proteins; D007141:Immunoglobulin Fc Fragments; D009587:Nitrogen Isotopes; D011522:Protons; C029702:prolactin-binding protein