title: Value of FNAC in diagnosis of different types of thyroiditis and its comparison with clinical and biochemical findings.
abstract: FNAC has developed tremendous improvement in the diagnosis of thyroiditis. The present study was designed to asses the usefulness of FNAC to diagnose various types of thyroiditis and to study their smear patterns. Over a period of one-year, 70 cases of thyroiditis have been evaluated on the basis of cytomorphological criteria and clinical findings of patients. The age ranged from 12-60 years. Majority of the cases were between 21 to 30 years of age with female preponderance in each group of thyroiditis. Among 70 cases, 26(37.14%) cases were Hashimoto's thyroiditis, 21(30%) cases were lymphocytic thyroiditis, seven (10%) cases as granulomatous thyroiditis and 16(22.8%) were non-specific thyroiditis. Further study was carried out in these 70 cases regarding biochemical thyroid status, ultrasonography and radionucleotide scan. Blood was drawn from all patients for estimation of antibody titer to compare with cytological diagnosis. It was found that, clinical examination and history of patients had limited value in the diagnosis of thyroiditis. Ultrasonography and thyroid scan could not reliably differentiate between patients with autoimmune thyroiditis and those with simple and nodular goiter. Biochemically hypothyroidism is more frequently evaluated with Hashimoto's diseases. On the other hand, hyperthyroidism was observed in most other types of thyroiditis. Cytologically diagnosed 78.72% cases of autoimmune thyroiditis had positive antibody titer. From the present study it is concluded that FNAC is a safe, reliable, cost effective and time saving method in the diagnosis of thyroiditis. Being a benign condition also reduce the rate of unnecessary operation, which can be treated conservatively.
authors.affiliation: Department of Pathology, Moulana Bhasani Medical Collage, Uttara, Dhaka, Bangladesh.
authors.forename: K
authors.initials: K
authors.lastname: Parveen
authors.forename: A R
authors.initials: AR
authors.lastname: Barua
authors.forename: A
authors.initials: A
authors.lastname: Hossain
authors.forename: J
authors.initials: J
authors.lastname: Zaman
authors.forename: A
authors.initials: A
authors.lastname: Momen
mesh_terms: D000293:Adolescent; D000328:Adult; D044963:Biopsy, Fine-Needle; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D050031:Hashimoto Disease / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013966:Thyroiditis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D055815:Young Adult