title: Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
abstract: Cerebral artery occlusion in childhood, particularly in the posterior circulation, is a rare neurological complication of Mycoplasma pneumoniae infection. A genetic defect in the methylenetetrahydrofolate reductase gene could result in hyperhomocysteinemia and increased risk of stroke. We report a patient with posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with a homozygous, methylenetetrahydrofolate reductase gene mutant type.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Ju Seok
authors.initials: JS
authors.lastname: Ryu
authors.forename: Ha Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: In Young
authors.initials: IY
authors.lastname: Sung
authors.forename: Tae Sung
authors.initials: TS
authors.lastname: Ko
mesh_terms: D000293:Adolescent; D001921:Brain / Q000098:blood supply / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D020762:Infarction, Posterior Cerebral Artery / Q000209:etiology* / Q000235:genetics* / Q000473:pathology; D018810:Magnetic Resonance Angiography; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D020125:Mutation, Missense; D009175:Mycoplasma Infections / Q000150:complications*; D009177:Mycoplasma pneumoniae; D017422:Sequence Analysis, DNA
chemical_list: D042965:Methylenetetrahydrofolate Reductase (NADPH2)