title: Comparative analysis of some modal reconstruction methods of the shape of the cornea from corneal elevation data.
abstract: OBJECTIVE
  A comparative study of the ability of some modal schemes to reproduce corneal shapes of varying complexity was performed, by using both standard radial polynomials and radial basis functions (RBFs). The hypothesis was that the correct approach in the case of highly irregular corneas should combine several bases.
  
  
  METHODS
  Standard approaches of reconstruction by Zernike and other types of radial polynomials were compared with the discrete least-squares fit (LSF) by the RBF in three theoretical surfaces, synthetically generated by computer algorithms in the absence of measurement noise. For the reconstruction by polynomials, the maximal radial order 6 was chosen, which corresponds to the first 28 Zernike polynomials or the first 49 Bhatia-Wolf polynomials. The fit with the RBF was performed by using a regular grid of centers.
  
  
  RESULTS
  The quality of fit was assessed by computing for each surface the mean square errors (MSEs) of the reconstruction by LSF, measured at the same nodes where the heights were collected. Another criterion of the fit quality used was the accuracy in recovery of the Zernike coefficients, especially in the case of incomplete data.
  
  
  CONCLUSIONS
  The Zernike (and especially, the Bhatia-Wolf) polynomials constitute a reliable reconstruction method of a nonseverely aberrated surface with a small surface regularity index (SRI). However, they fail to capture small deformations of the anterior surface of a synthetic cornea. The most promising approach is a combined one that balances the robustness of the Zernike fit with the localization of the RBF.
authors.affiliation: Department of Statistics and Applied Mathematics, Almería University, Almería, Spain. andrei@ual.es
authors.forename: Andrei
authors.initials: A
authors.lastname: Martinez-Finkelshtein
authors.forename: Antonia M
authors.initials: AM
authors.lastname: Delgado
authors.forename: Gracia M
authors.initials: GM
authors.lastname: Castro
authors.forename: Alejandro
authors.initials: A
authors.lastname: Zarzo
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Alió
mesh_terms: D003315:Cornea / Q000033:anatomy & histology*; D019781:Corneal Topography; D006801:Humans; D016018:Least-Squares Analysis; D008953:Models, Anatomic; D015233:Models, Statistical; D013499:Surface Properties