Whipple disease of the central nervous system: an unusual occurrence in association with acquired immune deficiency syndrome.
Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.
Guthikonda
Bharat
B
Department of Neurosurgery, LSU Health Science Center-Shreveport, Louisiana 71130-3932, USA. bguthi@lsuhsc.edu
Rouah
Emilie
E
Krishnan
Bhuvanaswari
B
Powell
Suzanne Z
SZ
Goodman
J Clay
JC
Gopinath
Shankar P
SP
Simpson
Richard K
RK
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D000328:Adult; D015153:Blotting, Western; D015704:CD4 Antigens / Q000276:immunology; D002494:Central Nervous System Infections / Q000382:microbiology / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008061:Whipple Disease / Q000150:complications* / Q000382:microbiology / Q000473:pathology*
D015704:CD4 Antigens