A nano-Ni based ultrasensitive nonenzymatic electrochemical sensor for glucose: enhancing sensitivity through a nanowire array strategy.
Highly ordered Ni nanowire arrays (NiNWAs) were synthesized for the first time using a template-directed electropolymerization strategy with a nanopore polycarbonate (PC) membrane template, and their morphological characterization were examined by scanning electron microscopy (SEM) and transmission electron microscope (TEM). A NiNWAs based electrode shows very high electrochemical activity for electrocatalytic oxidation of glucose in alkaline medium, which has been utilized as the basis of the fabrication of a nonenzymatic biosensor for electrochemical detection of glucose. The biosensor can be applied to the quantification of glucose with a linear range covering from 5.0x10(-7) to 7.0x10(-3) M, a high sensitivity of 1043 microA mM(-1) cm(-2), and a low detection limit of 1x10(-7) M. The experiment results also showed that the sensor exhibits good reproducibility and long-term stability, as well as high selectivity with no interference from other oxidable species.
Lu
Li-Min
LM
State Key Laboratory of Chemical Biosensing & Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
Zhang
Li
L
Qu
Feng-Li
FL
Lu
Hai-Xia
HX
Zhang
Xiao-Bing
XB
Wu
Zai-Sheng
ZS
Huan
Shuang-Yan
SY
Wang
Qiu-An
QA
Shen
Guo-Li
GL
Yu
Ru-Qin
RQ
D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D053770:Nanowires / Q000737:chemistry* / Q000648:ultrastructure; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction; D012680:Sensitivity and Specificity
D009532:Nickel; D005947:Glucose