Hodgkin lymphoma with cutaneous involvement.
We report a case of a 54-year-old previously healthy man with Hodgkin lymphoma who presented initially with a solitary cutaneous ulcer. Unlike non-Hodgkin lymphoma subtypes, skin involvement of Hodgkin lymphoma is extremely rare. Furthermore, the prognosis of Hodgkin lymphoma with skin infiltration is felt to be extremely poor. Contrary to other reports, this case demonstrates that a good response with standard therapy is possible.
Hsia
Cyrus C
CC
Department of Medicine, Division of Hematology, London Health Sciences Centre, London, Ontario, Canada. chsia@uwo.ca
Howson-Jan
Kang
K
Rizkalla
Kamilia S
KS
D015703:Antigens, CD / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006689:Hodgkin Disease / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000737:chemistry / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D016539:Reed-Sternberg Cells / Q000473:pathology; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D012883:Skin Ulcer / Q000209:etiology; D014747:Vinblastine / Q000008:administration & dosage
D015703:Antigens, CD; D000951:Antigens, Neoplasm; D001761:Bleomycin; D014747:Vinblastine; D003606:Dacarbazine; D004317:Doxorubicin