title: Synchronous renal cell carcinoma and clear cell hepatocellular carcinoma mimicking metastatic disease.
abstract: Double carcinomas of hepatocellular and renal cell carcinoma (RCC) are extremely rare, and among the reported cases, none of the hepatocellular carcinomas show clear cell change. We report a case of synchronous double primary clear cell tumor in the liver and the kidney of a 70-year-old male. The renal mass was a renal cell carcinoma of mixed clear and granular cell types, and the hepatic mass was a hepatocellular carcinoma with extensive clear cell change that mimicked a metastatic renal cell carcinoma. A simple battery of immunohistochemical stains composed of hepatocyte antigen, and CD10 was performed to make a definite diagnosis.
authors.affiliation: Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung 407, Taiwan.
authors.forename: Tai-Cheng
authors.initials: TC
authors.lastname: Hou
authors.forename: Chen-Chung
authors.initials: CC
authors.lastname: Wu
authors.forename: Chi-Re
authors.initials: CR
authors.lastname: Yang
authors.forename: John
authors.initials: J
authors.lastname: Wang
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*