A concise total synthesis of (+/-)-acutifolone A.
Starting from 4-methylcyclohexanone (7), a concise total synthesis of the pinguisane-type sesquiterpenoid acutifolone A, in racemic form, has been accomplished in 14 steps with an overall yield of 14.5%.
Hsieh
Ming-Tsang
MT
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, ROC.
Liu
Hsing-Jang
HJ
Ly
Tai Wei
TW
Shia
Kak-Shan
KS
D003500:Cyclization; D003510:Cyclohexanes / Q000737:chemistry*; D003979:Diazonium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013237:Stereoisomerism
D003510:Cyclohexanes; D003979:Diazonium Compounds; C506365:Cyclohexane; D010100:Oxygen