Efficient synthesis of the indoloazocine framework via intramolecular alkyne carbocyclization.
A microwave-assisted protocol based on an Hg(OTf)(2) catalyzed intramolecular alkyne carbocyclization reaction was developed for selective construction of the indoloazocine core.
Donets
Pavel A
PA
Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Katholieke UniVersiteit LeuVen,Celestijnenlaan 200F, B-3001 LeuVen, Belgium.
Van Hecke
Kristof
K
Van Meervelt
Luc
L
Van der Eycken
Erik V
EV
D000480:Alkynes / Q000737:chemistry*; D001392:Azocines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure
D000480:Alkynes; D001392:Azocines; D007211:Indoles