title: Should Lactobacillus sporogenes and Bacillus coagulans have a future?
abstract: Probiotics are gaining increasing scientific and commercial interest as functional foods. Their success has led to the development and marketing of a broad range of products based on probiotics. In this context, resolution of the taxonomy of microbial species remains a key point, since different species belonging to the same genus may have different beneficial properties. Lactobacillus sporogenes, which should be correctly classified as Bacillus coagulans, represents the archetypal misidentified probiotic and its inclusion among probiotics has often been a matter of debate. Since this bacterium shows characteristics of both genera Lactobacillus and Bacillus, its taxonomic position between the families lactobacillaceae and bacillaceae has often been discussed.This review summarizes the salient probiotic features of L. sporogenes /B. coagulans by examining currently available information. Although the use of L. sporogenes spores as a probiotic has increased in recent years, clinical evidence of its benefits are limited to only a few studies involving small patient populations.
authors.affiliation: Laboratory of Clinical Che,istry, IRCCS Galeazzi Hospital, University of Milan, Milan, Italy. lorenzo.drago@unimi.it
authors.forename: L
authors.initials: L
authors.lastname: Drago
authors.forename: E
authors.initials: E
authors.lastname: De Vecchi
mesh_terms: D001407:Bacillus / Q000145:classification*; D001430:Bacteriocins; D004064:Digestive System / Q000378:metabolism / Q000382:microbiology*; D058870:Food, Organic; D006801:Humans; D007778:Lactobacillus / Q000145:classification*; D019936:Probiotics
chemical_list: D001430:Bacteriocins; C114379:coagulin, Bacillus