title: Endovascular management of adult coarctation and its complications: intermediate results in a cohort of 22 patients.
abstract: OBJECTIVE
  To determine the safety and effectiveness of current endovascular treatment in adult patients with thoracic aortic coarctation and its complications.
  
  
  METHODS
  A cohort of 22 patients was treated for late presenting primary or recurrent coarctation or aneurysmal formation at varying intervals following childhood intervention.
  
  
  RESULTS
  Ten patients with recently discovered de novo coarctations were treated with balloon-expandable stents, and an endoluminal graft (ELG) was used in one additional patient. In the other 11 patients with recurrent lesions, three underwent repeat balloon dilation and stenting; eight patients with recurrence with aneurysms received ELGs. The gradients across the coarctation decreased from 49 + 16 to 4 + 7 mmHg (p = 0.001), and the diameters increased from 10 + 4 to 19 + 4mm (p = 0.001). In five of the eight patients (63%) with aneurysms, the ELG covered the subclavian artery, and a carotid subclavian bypass was necessary. Two patients required iliac artery access. No early major complications occurred. At mean follow-up of 31 + 15.6 months, one patient with type II leak resolved spontaneously and another developed neck dilation and type I leak, requiring a second ELG placement. All patients except one had improvements in symptoms and better hypertension control.
  
  
  CONCLUSIONS
  We conclude that primary or secondary endovascular intervention in adults with de novo or recurrent coarctation and aneurysms is feasible with good intermediate results.
authors.affiliation: Arizona Heart Institute and Hospital, Phoenix, AZ, USA. hanishennib@email.com
authors.forename: Hani
authors.initials: H
authors.lastname: Shennib
authors.forename: Julio
authors.initials: J
authors.lastname: Rodriguez-Lopez
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Ramaiah
authors.forename: Grayson
authors.initials: G
authors.lastname: Wheatley
authors.forename: Jacques
authors.initials: J
authors.lastname: Kpodonu
authors.forename: James
authors.initials: J
authors.lastname: Williams
authors.forename: Dawn
authors.initials: D
authors.lastname: Olson
authors.forename: Edward B
authors.initials: EB
authors.lastname: Diethrich
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000379:methods; D001013:Aorta, Thoracic / Q000002:abnormalities*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery; D001017:Aortic Coarctation / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult