title: NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein.
abstract: We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules.
authors.affiliation: Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, INSERM/UEVE U829-Université Evry-Val d'Essonne, Bâtiment Maupertuis, 91025, Evry, France.
authors.forename: Marie-Jeanne
authors.initials: MJ
authors.lastname: Clément
authors.forename: Philippe
authors.initials: P
authors.lastname: Savarin
authors.forename: Jérôme
authors.initials: J
authors.lastname: Coutant
authors.forename: Flavio
authors.initials: F
authors.lastname: Toma
authors.forename: Patrick
authors.initials: P
authors.lastname: Curmi
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D002247:Carbon Isotopes / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008869:Microtubule-Associated Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D011522:Protons; D014404:Tubulin / Q000737:chemistry*
chemical_list: C414735:CENPJ protein, human; D002247:Carbon Isotopes; D008869:Microtubule-Associated Proteins; D009587:Nitrogen Isotopes; D011522:Protons; D014404:Tubulin