title: Biological activity of quercetin-3-O-glucoside, a known plant flavonoid.
abstract: Cytotoxic, phytotoxic, antimicrobial and antioxidant effects of quercetin 3-O-glucoside (Q3G) isolated by HPLC from aerial parts of Prangos ferulaceae was studied by MTT assay, lettuce germination assay, disk diffusion and DPPH method. Our results showed that Q3G exhibits high antioxidant effect with RC(50) of 22 microg/mL, it has low cytotoxicity and no antibacterial effects. Q3G exhibits high phytotoxic effect with IC(50) value of 282.7 microg/ml, as well. It is assumed that Q3G does not play a defense role in plants and it may act as an allelopatic agent.
authors.affiliation: Department of Biology, Faculty of Sciences, University of Mohaghegh-Ardabili, Ardabil, Iran. razavi694@gmail.com
authors.forename: Seyed Mehdi
authors.initials: SM
authors.lastname: Razavi
authors.forename: Saber
authors.initials: S
authors.lastname: Zahri
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Zarrini
authors.forename: Hossein
authors.initials: H
authors.lastname: Nazemiyeh
authors.forename: Sariyeh
authors.initials: S
authors.lastname: Mohammadi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D003603:Cytotoxins / Q000737:chemistry / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010944:Plants / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000975:Antioxidants; D003603:Cytotoxins; D016166:Free Radical Scavengers; D010936:Plant Extracts; C016527:isoquercitrin; D011794:Quercetin