A short history of the long and productive search for the cause of subacute sclerosing panencephalitis.
This brief historical review recounts the efforts of the discovery of the cause of subacute sclerosing panencephalitis from its initial pathological descriptions, through the identification of measles virus as its pathogen, to the current conceptual framework of its pathogenesis. It is presented as an example of what was once considered an "unconventional" infection, but is now the subject of speculation according to the modern principles of molecular biology.
Katz
Michael
M
March of Dimes Foundation, 1275 Mamaroneck Avenue, White Plains, NY, USA.
D000818:Animals; D049673:History, 20th Century; D006801:Humans; D008459:Measles virus; D013344:Subacute Sclerosing Panencephalitis / Q000266:history* / Q000473:pathology / Q000821:virology*