NMR assignment of human granulocyte-macrophage colony-stimulating factor.
Human granulocyte-macrophage colony-stimulating factor (hGM-CSF), also known as sargramostim or molgramostin, is a cytokine that functions as a hematopoietic cell growth factor. Here we report a near complete assignment for the backbone and side chain resonances for the mature polypeptide.
Sauvé
Simon
S
Centre for Biologics Research, Biologics and Genetic Therapies Directorate, Health Canada, 251 Sir Frederick Banting Driveway, A/L 2201E, Tunney's Pasture, Ottawa, ON, Canada.
Gingras
Geneviève
G
Aubin
Yves
Y
D000595:Amino Acid Sequence; D002247:Carbon Isotopes / Q000737:chemistry; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D011522:Protons
D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D011522:Protons; D016178:Granulocyte-Macrophage Colony-Stimulating Factor