An overview of gene-epigenetic-environmental contributions to MS causation.
In this paper we review how environmental factors might interact with genes and epigenetic factors to trigger multiple sclerosis (MS), the latter probably by immune-mediated mechanisms.
Lincoln
John A
JA
University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA.
Cook
Stuart D
SD
D000818:Animals; D004777:Environment; D004843:Epistasis, Genetic; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000209:etiology* / Q000235:genetics*