title: Brucella serology in abattoir workers.
abstract: BACKGROUND
  Brucellosis is an occupational hazard with those particularly at risk either living in close proximity with animals or handling them. It is a public health problem in developing countries with adverse health implications both for animals and human beings as well as economic implications for individuals and communities. The Objectives were to estimate the seroprevalence of brucellosis among abattoir workers of Lahore District and to determine the association of brucellosis with nature of job of the workers.
  
  
  METHODS
  Data was collected in April 2008. It was a cross-sectional study in which four main slaughterhouses in Lahore were included. The slaughterhouse workers were divided into seven strata based on their nature of job: meat sellers, slaughterers, animal keepers, drivers, cleaners, loaders and vets/paravets. A total of 360 such workers were selected using stratified random sampling technique. Sampling frames for different strata were prepared and from each frame, proportionate numbers, were selected through simple random method using random number tables. Data was obtained using a questionnaire. Additionally blood samples were collected and analyzed for anti-Brucella Immunoglobulin G (IgG) using enzyme-linked immunosorbent assay (ELISA) technique.
  
  
  RESULTS
  The seroprevalence of anti-Brucella IgG was found to be 21.7%. A statistically significant difference was observed between the immune status of the respondents and their nature of job (p = 0.005), age groups (p = 0.013), and duration of job (p = 0.003).
  
  
  CONCLUSIONS
  The disease is an important public health problem in Pakistan. The disease can be prevented in the slaughterhouse workers through the use of personal protective devices. Public health authorities should educate the general public regarding prevention of the disease with specific emphasis on people working in slaughterhouses.
authors.affiliation: Department of Community Medicine, Lahore Medical and Dental College, Pakistan. fatimamukhtar@doctor.com
authors.forename: Fatima
authors.initials: F
authors.lastname: Mukhtar
authors.forename: Farkhanda
authors.initials: F
authors.lastname: Kokab
mesh_terms: D000003:Abattoirs; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002006:Brucellosis / Q000097:blood* / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood* / Q000453:epidemiology; D016273:Occupational Exposure; D010154:Pakistan / Q000453:epidemiology; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires
chemical_list: D007074:Immunoglobulin G