title: The influence of application of different desensitisers on root dentine demineralisation in situ.
abstract: OBJECTIVE
  To evaluate the influence of three desensitisers on root caries demineralisation in situ.
  
  
  METHODS
  The root surfaces of 36 freshly extracted human molars were used to prepare root dentine specimens. These specimens were distributed among the following groups: A: Admira Protect, V: VivaSens, H: Hyposen, C: control group, untreated. Two dentine specimens of each group were inserted into two buccal aspects of intraoral mandibular appliances. The appliances were worn by nine persons for five weeks, day and night. One side was brushed daily with a toothpaste. On the other side, plaque was allowed to grow. Individual oral hygiene techniques were performed without any fluorides. After the in situ period, two slabs were ground. The depth of the demineralised areas was determined using a polarised light microscope.
  
  
  RESULTS
  ANOVA revealed significant differences between brushed and non-brushed specimens. Lesion depths in the brushed group were significantly decreased (p < 0.05, Tukey's test).
  
  
  CONCLUSIONS
  Within the limitations of an in situ study it can be concluded that the demineralisation of the root surface can be hampered by application of desensitisers under different oral hygiene conditions. The application of clinical proven desensitising agents might have a caries-protective effect on exposed root surfaces.
authors.affiliation: Martin-Luther University Halle-Wittenberg, University School of Dental Medicine, Department of Operative Dentistry and Periodontology, Halle, Germany. katrin.bekes@medizin.uni-halle.de
authors.forename: Katrin
authors.initials: K
authors.lastname: Bekes
authors.forename: Melanie
authors.initials: M
authors.lastname: Schmelz
authors.forename: Hans-Guenter
authors.initials: HG
authors.lastname: Schaller
authors.forename: Christian Ralf
authors.initials: CR
authors.lastname: Gernhardt
mesh_terms: D019905:Benzyl Alcohol / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use*; D003188:Composite Resins / Q000627:therapeutic use; D003807:Dentin Sensitivity / Q000188:drug therapy*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D017213:Root Caries / Q000517:prevention & control*; D013324:Strontium / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D017220:Dentin-Bonding Agents; C527768:Hyposen; C525245:VivaSens Liner; C532400:admira protect; D019905:Benzyl Alcohol; D013324:Strontium