Visceral leishmaniasis associated hemophagocytic syndrome in patients with chronic granulomatous disease.
Visceral leishmaniasis is a severe form of infection caused by a parasite endemic along the Mediterranean coast. Complications such as infection-associated hemophagocytic syndrome can occur despite correct therapy. We report visceral leishmaniasis-associated infection-associated hemophagocytic syndrome in 3 patients with chronic granulomatous disease.
Martín
Andrea
A
Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Hospital, Barcelona, Spain. 37904amn@comb.es
Marques
Laura
L
Soler-Palacín
Pere
P
Caragol
Isabel
I
Hernandez
Manuel
M
Figueras
Concepcion
C
Español
Teresa
T
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D008297:Male; D011994:Recombinant Proteins
D000981:Antiprotozoal Agents; D011994:Recombinant Proteins; C068538:liposomal amphotericin B; D000666:Amphotericin B; D007371:Interferon-gamma