title: Treatment of eyelid xanthelasma with 70% trichloroacetic acid.
abstract: OBJECTIVE
  To analyze the results of treatment of eyelid xanthelasma (EX) with 70% trichloroacetic acid (TCA) with regard to efficacy, cosmetic appearance, patient satisfaction, and recurrence rate.
  
  
  METHODS
  Twenty-four patients with EX of up to one third of the affected palpebral area were treated with 70% TCA. All patients were photographed at the start of treatment and 3 months after the last application. The recurrence rate was analyzed at the end of 6 months of treatment.
  
  
  RESULTS
  The average number of applications of 70% TCA until the xanthelasma resolved was 1.5. Eleven patients (45.8%) had an excellent result, 8 (33.3%) a good result, and 5 (20.8%) had a satisfactory result. The most common complication was hypopigmentation (33.3%). All patients reported an improved final cosmetic result. Six patients (25%) treated with 70% TCA had a recurrence 6 months after treatment.
  
  
  CONCLUSIONS
  The results of prospective treatment of 24 patients with EX with 70% TCA indicated that this is a simple and effective method, achieves a satisfactory cosmetic result, has an acceptable recurrence rate, and high patient satisfaction.
authors.affiliation: Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil. tatinahas@uol.com
authors.forename: Tatiana Rizkallah
authors.initials: TR
authors.lastname: Nahas
authors.forename: Junia Cabral
authors.initials: JC
authors.lastname: Marques
authors.forename: André
authors.initials: A
authors.lastname: Nicoletti
authors.forename: Marcos
authors.initials: M
authors.lastname: Cunha
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Nishiwaki-Dantas
authors.forename: José Vital
authors.initials: JV
authors.lastname: Filho
mesh_terms: D000328:Adult; D000368:Aged; D002424:Caustics / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005141:Eyelid Diseases / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D017060:Patient Satisfaction; D011446:Prospective Studies; D016896:Treatment Outcome; D014238:Trichloroacetic Acid / Q000627:therapeutic use*; D014973:Xanthomatosis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D002424:Caustics; D009883:Ophthalmic Solutions; D014238:Trichloroacetic Acid