The new HLA-Cw*0524 allele increase the variability of position 49 in HLA-C.
The identification of the novel human leukocyte antigen (HLA)-Cw*0524, which was found in a potential stem cell donor, is described. The sequence of the new allele differs from HLA-Cw*0501 and HLA-Cw*0503 by a nonsynonymous amino acid (AA) exchanges at position 49.
Figueiredo
C
C
Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.
Jaimes
Y
Y
Horn
P A
PA
Blasczyk
R
R
Eiz-Vesper
B
B
D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001483:Base Sequence; D005091:Exons; D014644:Genetic Variation; D005998:Glycine / Q000378:metabolism; D015236:HLA-C Antigens / Q000737:chemistry / Q000235:genetics*; D006239:Haplotypes; D015395:Histocompatibility Antigens Class I / Q000235:genetics; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D017434:Protein Structure, Tertiary / Q000235:genetics; D013234:Stem Cells / Q000166:cytology; D009626:Terminology as Topic; D014019:Tissue Donors
D015236:HLA-C Antigens; D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II; D005998:Glycine