title: [Population data of five STRs from the INTERPOL series in a mestizo population of western Mexico (State of Jalisco)].
abstract: BACKGROUND
  Short tandem repeats (STRs) are the DNA polymorphisms most widely used in forensic genetics and parentage testing. Most common series of STRs are those from FBI (CODIS) and from INTERPOL. While there are data related to the first group, no studies are still known in Mexican populations in regard of the INTERPOL set.
  
  
  OBJECTIVE
  To describe the genetic characteristics of five INTERPOL STRs and to estimate their main forensic parameters in a population from western Mexico.
  
  
  METHODS
  Samples from 100 random volunteers from the State of Jalisco were PCR typed for STRs F13B, D2S1338, FESFPS, Penta D and Penta E.
  
  
  RESULTS
  Genotype proportions in all five STRs were in agreement with Hardy-Weinberg expectations (p > 0.05). Heterocygosity varied from 0.68 for FESFPS to 0.91 for Penta E markers. Power of discrimination (PD) and exclusion probability (EP) were in the 0.83-0.97 and 0.46-0.75 ranges, respectively. The five combined STRs give a PE > 0.99143 and PD > 0.99999.
  
  
  CONCLUSIONS
  These results contribute to establish data bases representative of western Mexico and are useful in DNA forensic and parentage studies.
authors.affiliation: Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social. antquintero@yahoo.com.mx
authors.forename: Antonio
authors.initials: A
authors.lastname: Quintero-Ramos
authors.forename: Jorge R
authors.initials: JR
authors.lastname: Padilla-Gutiérrez
authors.forename: Guillermo
authors.initials: G
authors.lastname: Hernández-Zaragoza
authors.forename: Yeminia
authors.initials: Y
authors.lastname: Valle
authors.forename: Laura L
authors.initials: LL
authors.lastname: Valdez-Velázquez
authors.forename: Norma
authors.initials: N
authors.lastname: Olivares
authors.forename: Fernando
authors.initials: F
authors.lastname: Rivas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000483:Alleles; D044383:Black People / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D005787:Gene Frequency; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D018895:Microsatellite Repeats; D008875:Middle Aged; D012494:Sampling Studies; D013030:Spain / Q000208:ethnology; D044465:White People / Q000235:genetics*; D055815:Young Adult
chemical_list: D005819:Genetic Markers