Convenient and efficient preparations of azodye-labeled peptides.
N-(4-Arylazobenzoyl)-1H-benzotriazoles 15a, 15b react with dipeptides 12a-d, (12d+12d') and tripeptides 14a, 14b to give azodye labeled-dipeptides (16a-e), (16d+16d'), (16e+16e') and -tripeptides 16f, 16g in high yields (73-93%) with retention of chirality.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
Chen
Qi-Yin
QY
Tala
Srinivasa R
SR
D000595:Amino Acid Sequence; D001391:Azo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D004396:Coloring Agents / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D013194:Staining and Labeling
D001391:Azo Compounds; D002264:Carboxylic Acids; D004396:Coloring Agents; D010455:Peptides