No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome.
Restless legs syndrome is a common disorder that may interrupt sleep and has been reported to produce daytime fatigue and/or mood changes. This study assessed whether patients with RLS have more cognitive dysfunction and depression than individuals of the same age and education who do not have RLS. The study showed that older individuals with mild RLS for at least 1 year do not have cognitive dysfunction and are not depressed compared with a control group of similar age and education.
Driver-Dunckley
Erika
E
Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, USA. driverdunckley.erika@mayo.edu
Connor
Donald
D
Hentz
Joe
J
Sabbagh
Marwan
M
Silverberg
Nina
N
Hernandez
Jose
J
Vedders
Linda
L
Evidente
Virgilio Gerald
VG
Shill
Holly
H
Caviness
John
J
Adler
Charles
C
D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D006801:Humans; D009483:Neuropsychological Tests; D017286:Polysomnography; D011569:Psychiatric Status Rating Scales; D012148:Restless Legs Syndrome / Q000150:complications* / Q000188:drug therapy; D012720:Severity of Illness Index