title: Klebsiella pneumoniae clinical isolate coproducing SHV-2a, DHA-1, QnrB4, and AAC(6')-Ib-cr determinants in France.
abstract: We report on a Klebsiella pneumoniae clinical isolate coproducing bla(DHA-1), bla(SHV-2a), qnrB4, and aac(6')-Ib-cr genes. Molecular analysis demonstrated the presence of this combination on the same large plasmid. Despite a negative result for extended-spectrum beta-lactamase (ESBL) by Vitek2(R) system (bioMérieux, Marcy-l'Etoile, France), an ESBL was detected by a double-disk test. Phenotypic techniques and molecular analysis are key approaches to determine coresistance.
authors.affiliation: Service de Bactériologie-Hygiène Hospitalière, CHU de Nantes, 9 quai Moncousu, 44093 Nantes Cedex 01, France. stephane.corvec@chu-nantes.fr
authors.forename: Stéphane
authors.initials: S
authors.lastname: Corvec
authors.forename: Lise
authors.initials: L
authors.lastname: Crémet
authors.forename: Nathalie
authors.initials: N
authors.lastname: Caroff
authors.forename: Sandie
authors.initials: S
authors.lastname: Dauvergne
authors.forename: Ronan
authors.initials: R
authors.lastname: Le Floch
authors.forename: Alain
authors.initials: A
authors.lastname: Reynaud
authors.forename: Didier
authors.initials: D
authors.lastname: Lepelletier
authors.forename: Pascale
authors.initials: P
authors.lastname: Bémer
mesh_terms: D024881:Drug Resistance, Bacterial; D005602:France; D005798:Genes, Bacterial; D006801:Humans; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D010957:Plasmids; D055815:Young Adult