title: [A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy].
abstract: A 75-year-old man was diagnosed with gastric cancer (UL post c0- II c (c T1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1). The patient was treated with modified (m) FOLFOX6 regimen (oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin). Chest and abdominal CT scan revealed that multiple lung metastases and abdominal lymph node metastases were obviously reduced in size. The primary lesion of the rectum almost disappeared on endoscopic examination. As for the lesions of the stomach, the UL post c0- II c lesion completely disappeared, and the M-less ctype II lesion was reduced remarkably. Thus, a significant reduction of the tumors was observed. This case suggests that mFOLFOX6 regimen can be an option for gastric cancer.
authors.affiliation: Dept. of Surgery, Ishinomaki Redcross Hospital.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ishii
authors.forename: Iwao
authors.initials: I
authors.lastname: Kaneda
authors.forename: Akihiko
authors.initials: A
authors.lastname: Furuta
authors.forename: Masaru
authors.initials: M
authors.lastname: Shoji
authors.forename: Satoru
authors.initials: S
authors.lastname: Ishibashi
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Hatsugai
authors.forename: Masato
authors.initials: M
authors.lastname: Ohara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sarashina
authors.forename: Hiroo
authors.initials: H
authors.lastname: Masuoka
authors.forename: Yuki
authors.initials: Y
authors.lastname: Sekine
authors.forename: Go
authors.initials: G
authors.lastname: Watanabe
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy*; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D012004:Rectal Neoplasms / Q000188:drug therapy*; D013274:Stomach Neoplasms / Q000188:drug therapy*; D014803:Vitamin B Complex / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D014803:Vitamin B Complex; D002955:Leucovorin; D005472:Fluorouracil