NMR assignment of the C-terminal actin-binding domain of talin.
Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin beta-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.
Goult
Benjamin T
BT
Department of Biochemistry, University of Leicester, Lancaster Road, Leicester LE19HN, UK.
Gingras
Alexandre R
AR
Bate
Neil
N
Roberts
Gordon C K
GC
Critchley
David R
DR
Barsukov
Igor L
IL
D000199:Actins / Q000737:chemistry*; D000595:Amino Acid Sequence; D001665:Binding Sites; D002247:Carbon Isotopes / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D011485:Protein Binding; D011522:Protons; D016608:Talin / Q000737:chemistry*
D000199:Actins; D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D011522:Protons; D016608:Talin