title: [Endotoxin deactivation in artificial glass root canals with ultrasonic treatment].
abstract: OBJECTIVE
  To study the deactivation of the endotoxin in artificial glass root canals with ultrasonic vibration.
  
  
  METHODS
  80 artificial glass root canals were randomly divided into 8 groups: Ultrasonic vibration of 5 minutes, 7 minutes, 10 minutes, ultrasonic vibration of 5 minutes together with 3% H2O2 solution, only 3% H2O2 solution, ultrasonic vibration of 5 minutes together with 5.25% NaClO solution, only 5.25% NaClO solution and the control. Standard endotoxin solution was introduced into each root canal. Different time's ultrasonic vibration was applied to different groups. After ultrasonic vibration, the endotoxin activity of each group was tested by kinetic turbidimetric limulus test.
  
  
  RESULTS
  There were no significant differences among the groups of different time ultrasonic vibration and the control (P>0.05). There was great statistical difference between each group with root canal rinse solution and the control (P<0.001). The endotoxin activity of the test was significantly lower than the control. There was no significant difference between the groups of only rinse solution and rinse solution together with ultrasonic vibration.
  
  
  CONCLUSIONS
  Under the condition of this study, the only ultrasonic vibration can not deactivate the endotoxin of infected root canals and can not intensify the effect of root canal rinse solution.
authors.affiliation: Dept. of Conservative Dentistry and Endodontics, Stomatological Hospital, Shandong University, Jinan 250012, China.
authors.forename: Gui-Xiang
authors.initials: GX
authors.lastname: Liu
authors.forename: Qing
authors.initials: Q
authors.lastname: Wang
authors.forename: Lin-Wang
authors.initials: LW
authors.lastname: Su
mesh_terms: D003786:Dental Pulp Cavity; D004731:Endotoxins; D006861:Hydrogen Peroxide; D014465:Ultrasonics; D014732:Vibration
chemical_list: D004731:Endotoxins; D006861:Hydrogen Peroxide