title: Commissioning a passive-scattering proton therapy nozzle for accurate SOBP delivery.
abstract: Proton radiotherapy centers that currently use passively scattered proton beams do field specific calibrations for a non-negligible fraction of treatment fields, which is time and resource consuming. Our improved understanding of the passive scattering mode of the IBA universal nozzle, especially of the current modulation function, allowed us to re-commission our treatment control system for accurate delivery of SOBPs of any range and modulation, and to predict the output for each of these fields. We moved away from individual field calibrations to a state where continued quality assurance of SOBP field delivery is ensured by limited system-wide measurements that only require one hour per week. This manuscript reports on a protocol for generation of desired SOBPs and prediction of dose output.
authors.affiliation: Department of Radiation Oncology, Francis H. Burr Proton Therapy Center Massachusetts General Hospital, Boston, Massachusetts 02114, USA. mengelsman@partners.org
authors.forename: M
authors.initials: M
authors.lastname: Engelsman
authors.forename: H M
authors.initials: HM
authors.lastname: Lu
authors.forename: D
authors.initials: D
authors.lastname: Herrup
authors.forename: M
authors.initials: M
authors.lastname: Bussiere
authors.forename: H M
authors.initials: HM
authors.lastname: Kooy
mesh_terms: D000465:Algorithms; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D061766:Proton Therapy; D011874:Radiometry / Q000379:methods* / Q000592:standards*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000592:standards*; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D014481:United States; D011522:Protons
chemical_list: D011522:Protons