1H, 13C and 15N resonance assignments of the PDZ of microtubule-associated serine/threonine kinase 205 (MAST205) in complex with the C-terminal motif from the rabies virus glycoprotein.
Most of microbes hijack the cellular machinery to their advantage by interacting with specific target of the host cell. Glycoprotein of rabies virus is a key factor controlling the homeostasis of infected neuronal cells and proteins belonging to the human microtubule associated serine threonine kinase family have been identified as potential cellular partners. As a first step towards its structural study, we have assigned the backbone and side chain nuclei resonances of the PDZ domain (PSD-95, Discs Large, ZO-1) of MAST205 in complex with the C-terminal residues of the glycoprotein of rabies virus. The BMRB accession code is 155972.
Terrien
Elouan
E
Unité de Résonance Magnétique Nucléaire des Biomolécules, Département de Biologie Structurale et Chimie, CNRS URA 2185, Institut Pasteur, 28, rue du Docteur Roux, 75724, Paris Cedex 15, France.
Simenel
Catherine
C
Prehaud
Christophe
C
Buc
Henri
H
Delepierre
Muriel
M
Lafon
Monique
M
Wolff
Nicolas
N
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D001665:Binding Sites; D002247:Carbon Isotopes / Q000737:chemistry; D006023:Glycoproteins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008869:Microtubule-Associated Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D046912:Multiprotein Complexes / Q000737:chemistry; D009587:Nitrogen Isotopes / Q000737:chemistry; D011485:Protein Binding; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry*; D017434:Protein Structure, Tertiary; D011522:Protons; D011820:Rabies virus / Q000737:chemistry*; D014764:Viral Proteins / Q000737:chemistry*
D002247:Carbon Isotopes; D006023:Glycoproteins; D008869:Microtubule-Associated Proteins; C084505:Mtssk protein, mouse; D046912:Multiprotein Complexes; D009587:Nitrogen Isotopes; D011522:Protons; D014764:Viral Proteins; D017346:Protein Serine-Threonine Kinases