title: Efficient 3D numerical approach for temperature prediction in laser irradiated biological tissues.
abstract: Temperature prediction in biological tissues irradiated by an optical source is frequently required in some medical applications, like Thermotherapy, Hyperthermia or tissue ablation. In this work we propose a new numerical approach to solve the bio-heat equation. It is based on the two steps 3D modified Du Fort-Frankel algorithm, which allows a better convergence, more accuracy and a faster computation than previous numerical methods developed by other authors. The model also includes adaptive spatial mesh and time step refinement. These improved results for opto-thermal temperature distribution could be used for choosing appropriate laser treatment parameters in medical praxis.
authors.affiliation: Applied Optical Techniques Group, TEISA Department, University of Cantabria, Santander, Spain. fanjulf@unican.es
authors.forename: Félix
authors.initials: F
authors.lastname: Fanjul-Vélez
authors.forename: Oleg G
authors.initials: OG
authors.lastname: Romanov
authors.forename: José Luis
authors.initials: JL
authors.lastname: Arce-Diego
mesh_terms: D000465:Algorithms; D001698:Biomedical Engineering; D055592:Biophysical Phenomena; D003198:Computer Simulation; D006358:Hot Temperature; D006801:Humans; D053685:Laser Therapy / Q000706:statistics & numerical data*; D008954:Models, Biological; D012867:Skin / Q000528:radiation effects; D012881:Skin Temperature / Q000528:radiation effects; D013696:Temperature