title: Depressive disorders in stroke patients.
abstract: Post-stroke depression is a serious complication of ischemic stroke which has negative influences on patients' quality of life and on recovery from symptoms and the prognosis of the underlying disease. We report here a study of the efficacy of treatment of patients with post-stroke depression with Opra, showing improvements in status in 93.3% of patients. Along with its antidepressant action, Opra had a marked anxiolytic effect. The agent had no adverse effects on the activities of daily living or cognitive functions, and produced minimal side effects.
authors.affiliation: Department of Neurology and Neurosurgery, Russian State Medical University, Moscow, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Gusev
authors.forename: A N
authors.initials: AN
authors.lastname: Bogolepova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D015283:Citalopram / Q000009:adverse effects / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D015283:Citalopram