Cell-permeable [99mTc(CO3)]-labeled fluorogenic caspase 3 substrate for dual-modality detection of apoptosis.
Xiong
Chiyi
C
Department of Diagnostic Imaging, U.T.M.D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Lu
Wei
W
Zhang
Rui
R
Tian
Mei
M
Tong
William
W
Gelovani
Juri
J
Li
Chun
C
D000818:Animals; D017209:Apoptosis; D053148:Caspase 3 / Q000378:metabolism*; D045744:Cell Line, Tumor; D002463:Cell Membrane Permeability; D002851:Chromatography, High Pressure Liquid; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008856:Microscopy, Fluorescence; D015394:Molecular Structure; D015609:Organotechnetium Compounds / Q000737:chemistry*; D011868:Radioisotopes / Q000378:metabolism; D011877:Radionuclide Imaging; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000737:chemistry* / Q000378:metabolism*
D005456:Fluorescent Dyes; D015609:Organotechnetium Compounds; D011868:Radioisotopes; D053221:TNF-Related Apoptosis-Inducing Ligand; D053148:Caspase 3