title: [Influence of effect of Suxiao Jiuxinwan on angiogenesis in experimental myocardial infarction rats].
abstract: OBJECTIVE
  To study the effect of Suxiao Jiuxinwan on angiogenesis in experimental myocardial infarction rats.
  
  
  METHODS
  The animal model was established by ligation of anterior decending coronary artery and the infarction areas as well as microvascular density (MVD) in the marginal infarction area of the myocardial infarction rats were observed.
  
  
  RESULTS
  Infarction areas in high dose and low dose Suxiao Jiuxinwan groups were significantly different from that of model group (P<0.01), and this effect was similar with the positive model group and had the dosage-dependent speciality. The microvascular density (MVD) of marginal infarction areas in Suxiao Jiuxinwan high and low groups was much more elevated than that in the sham group (P<0.05), and the effect of Suxiao Jiuxinwan high group was similar with that of the positive control group. But the difference between the Suxiao Jiuxinwan high and the low goups was not significant.
  
  
  CONCLUSIONS
  Suxiao Jiuxinwan has the obvious effcet on angiogenesis in eperimental myocardial infarction rats.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Feng
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Shuanghou
authors.initials: S
authors.lastname: Cheng
authors.forename: Riuhua
authors.initials: R
authors.lastname: Liu
authors.forename: Fuyong
authors.initials: F
authors.lastname: Chu
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D055806:Microvessels / Q000187:drug effects / Q000503:physiopathology; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology*; D009389:Neovascularization, Pathologic / Q000188:drug therapy*; D051381:Rats
chemical_list: D004365:Drugs, Chinese Herbal; C543119:suxiao jiuxinwan