A conventional route to scalable morphology-controlled regular structures and their superhydrophobic/hydrophilic properties for biochips application.
We use a conventional and straightforward route to fabricate scalable morphology-controlled regular structures. This route is based on the etching of PDMS microlens array in CF4 and CF4/O2 plasma. PDMS microlens array can be changed to regularly isolated microdot structures array in CF4 plasma. Microbowl shaped structures array can be reached in CF4/O2 plasma. Moreover, a set of structures after CF4 plasma treatment display superhydrophobicity, while a set of structures after CF4/O2 plasma treatment present hydrophilicity. DNA molecules can be readily enriched on the hydrophilic surface. We believe that the regular structure array surfaces provide a useful inspiration towards biomolecular detection and transportation in biochips.
Ren
Hong-Xuan
HX
School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210098, PR China.
Chen
Xing
X
Huang
Xing-Jiu
XJ
Im
Maesoon
M
Kim
Dong-Haan
DH
Lee
Joo-Hyung
JH
Yoon
Jun-Bo
JB
Gu
Ning
N
Liu
Jin-Huai
JH
Choi
Yang-Kyu
YK
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004277:DNA, Single-Stranded / Q000032:analysis; D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D007909:Lenses; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D010100:Oxygen / Q000737:chemistry; D017155:Wettability
D004277:DNA, Single-Stranded; D004129:Dimethylpolysiloxanes; D006845:Hydrocarbons, Fluorinated; C013830:baysilon; C538689:tetrafluoromethane; D010100:Oxygen