Fundamental relationships between structure, reactivity, and biological activity for the duocarmycins and CC-1065.
MacMillan
Karen S
KS
Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, USA.
Boger
Dale L
DL
D000477:Alkylating Agents / Q000737:chemistry / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000494:pharmacology; D000080890:Duocarmycins; D007211:Indoles / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D011758:Pyrroles / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000477:Alkylating Agents; D000903:Antibiotics, Antineoplastic; D000080890:Duocarmycins; D007211:Indoles; D011758:Pyrroles; C066098:duocarmycin SA; C018782:CC 1065