title: MAPK cascade signalling networks in plant defence.
abstract: The sensing of stress signals and their transduction into appropriate responses is crucial for the adaptation and survival of plants. Kinase cascades of the mitogen-activated protein kinase (MAPK) class play a remarkably important role in plant signalling of a variety of abiotic and biotic stresses. MAPK cascade-mediated signalling is an essential step in the establishment of resistance to pathogens. Here, we describe the most recent insights into MAPK-mediated pathogen defence response regulation with a particular focus on the cascades involving MPK3, MPK4 and MPK6. We also discuss the strategies developed by plant pathogens to circumvent, inactivate or even 'hijack' MAPK-mediated defence responses.
authors.affiliation: Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
authors.forename: Andrea
authors.initials: A
authors.lastname: Pitzschke
authors.forename: Adam
authors.initials: A
authors.lastname: Schikora
authors.forename: Heribert
authors.initials: H
authors.lastname: Hirt
mesh_terms: D016960:Agrobacterium tumefaciens / Q000502:physiology; D004789:Enzyme Activation; D054884:Host-Pathogen Interactions; D007113:Immunity, Innate; D020935:MAP Kinase Signaling System; D020928:Mitogen-Activated Protein Kinases / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology; D044224:Pseudomonas syringae / Q000502:physiology
chemical_list: D010940:Plant Proteins; D020928:Mitogen-Activated Protein Kinases