title: Effects of preoperative magnesium therapy on arrhythmias and myocardial ischemia during off-pump coronary surgery.
abstract: BACKGROUND
  Heart manipulation during off-pump coronary artery bypass surgery may cause hemodynamic instability, and temporary coronary arterial occlusion may lead to myocardial ischemia. To reduce this, perioperative β-blocking agents or calcium antagonists can be administrated. The effects of perioperative administration of magnesium on myocardial function were studied in patients undergoing coronary artery bypass grafting.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the effects of preoperative magnesium administration on perioperative hemodynamia, ventricular arrhythmias and myocardial protection.
  
  
  METHODS
  We reviewed 2 groups of patients undergoing off-pump coronary artery bypass surgery - 24 patients (control group) that had not received preoperative intravenous infusion of magnesium and 23 patients (treatment group) that had received preoperative intravenous magnesium sulfate.
  
  
  RESULTS
  The results demonstrated that it had reduced the heart rate, changes of ST segments, the need of β-blocking agents and the use of intra-operative intra-aortic balloon pump and the inotropic usage.
  
  
  CONCLUSIONS
  This treatment may provide hemodynamic optimization during off-pump coronary artery bypass.
authors.affiliation: Department of Cardiovascular Surgery, Osmangazi University Medical School and Research Hospital, Eskişehir, Turkey. ybesogul@gmail.com
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Beşoğul
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Gemalmaz
authors.forename: Recep
authors.initials: R
authors.lastname: Aslan