[Predictors of chronic renal failure in patients in a hypertension center].
OBJECTIVE
To verify which clinical variables can predict the evolution to chronic renal insufficiency in routinely evaluated hypertensives.


METHODS
358 patients from the Hypertension Center of the Botucatu School of Medicine (São Paulo State University) were evaluated. Sequential evaluation of glomerular filtration rate was detected in 210 patients, who were analyzed. Logistic regression was applied to identify clinical variables independently associated with the development of chronic renal insufficiency with a final glomerular filtration rate equal to or below 60 ml/min.


RESULTS
In routine urinalysis only proteinuria was independently associated with the outcome. Among 175 patients with initial glomerular filtration rate above 60 ml/min, proteinuria, female gender and age of 50 years or more were predictors of the evolution to a final glomerular filtration rate equal to or below 60 ml/min.


CONCLUSIONS
The presence of proteinuria in simple urinalysis was a risk factor and a reliable predictor associated with the development of chronic renal insufficiency among hypertensives.
Moraes
Cinthia Esbrile
CE
Faculdade de Medicina de Botucatu, Botucatu, SP.
Cerolli
Camila Farias
CF
Silva
Vanessa Santos
VS
Franco
Roberto Jorge da Silva
RJ
Habermann
Francisco
F
Matsubara
Beatriz Bojikian
BB
Martin
Luis Cuadrado
LC
D015415:Biomarkers / Q000652:urine; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000209:etiology / Q000652:urine*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011507:Proteinuria / Q000652:urine; D012016:Reference Values; D012307:Risk Factors
D015415:Biomarkers