title: H1N1 swine origin influenza infection in the United States and Europe in 2009 may be similar to H1N1 seasonal influenza infection in two Australian states in 2007 and 2008.
abstract: BACKGROUND
  The population-based impact of infection with swine origin influenza A (H1N1) virus infection was not clear in the early days of the epidemic towards the end of May 2009. Australia had seven confirmed cases by 22 May 2009. We aimed to compare available data on swine origin influenza A (H1N1) virus infection overseas with seasonal influenza A (H1N1) virus infection in Australia to assist with forward planning.
  
  
  METHODS
  Data on infection with seasonal influenza A (H1N1) virus in patients recruited through sentinel general practices in Victoria and Western Australia in 2007 and 2008 were compared with early publications on infection with swine origin influenza A (H1N1) virus in the United States and Europe.
  
  
  RESULTS
  Influenza A (H1N1) virus infection was predominantly a disease of younger people, regardless of whether the virus was of swine or human origin. The median age of infection with swine origin virus was 20 years in the United States and 22 years in Spain, while the median age of infection with human origin virus was 18 years in Western Australia and 23 years in Victoria.
  
  
  CONCLUSIONS
  The median age of infection with influenza A (H1N1) virus was around 20 +/- 3 years, independent of the origin of the H1N1 virus but a higher proportion of swine origin influenza infections occurred in people aged 10-18 years. This is at least partially explained by biased sampling among surveillance patients, although it may also reflect a different infection pattern.
authors.affiliation: Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia. heath.kelly@mh.org.au
authors.forename: Heath
authors.initials: H
authors.lastname: Kelly
authors.forename: Kristina
authors.initials: K
authors.lastname: Grant
authors.forename: Simon
authors.initials: S
authors.lastname: Williams
authors.forename: David
authors.initials: D
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology; D008875:Middle Aged; D013030:Spain / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D014739:Victoria / Q000453:epidemiology; D014904:Western Australia / Q000453:epidemiology; D055815:Young Adult