Condyloma overgrowth caused by immune reconstitution inflammatory syndrome.
A 46-year-old man with human immunodeficiency virus presented with a condyloma that formed during 6 months and encased his penis, scrotum, and perineum. Visible condyloma growth began when this immunocompromised patient started highly active antiretroviral therapy, and it grew rapidly as his viral load plummeted. The patient underwent resection and reconstruction with skin grafting. Pathology findings revealed benign condyloma acuminatum. This rapid progression of condyloma growth is a cutaneous manifestation of immune reconstitution inflammatory syndrome.
Weiss
Dana A
DA
Department of Urology, University of California, San Francisco, California, USA. dweiss@urology.ucsf.edu
Yang
Glen
G
Myers
Jeremy B
JB
Breyer
Benjamin N
BN
D003218:Condylomata Acuminata / Q000276:immunology* / Q000473:pathology*; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000276:immunology* / Q000473:pathology*