title: Aortic and mitral valve replacement with reconstruction of the intervalvular fibrous body in familial hypercholesterolemia.
abstract: We report a case of a 22-year-old woman with a known history of homozygous familial hypercholesterolemia. The patient was admitted to our hospital with the chief complaints of chest discomfort and dyspnea on exertion. Preoperative echocardiography revealed highly echogenic aortic and mitral valves as well as a narrowed aortic root. A surgical procedure consisting of both aortic and mitral valve replacement with reconstruction of the intervalvular fibrous body was performed.
authors.affiliation: Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, 200433 Shanghai, People's Republic of China.
authors.forename: H
authors.initials: H
authors.lastname: Jin
authors.forename: F
authors.initials: F
authors.lastname: Yao
authors.forename: Z-G
authors.initials: ZG
authors.lastname: Li
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Xu
mesh_terms: D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D000069059:Atorvastatin; D001781:Blood Component Removal; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000150:complications* / Q000628:therapy; D008077:Lipoproteins, LDL / Q000097:blood; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D011758:Pyrroles / Q000627:therapeutic use; D016896:Treatment Outcome; D014973:Xanthomatosis / Q000209:etiology; D055815:Young Adult
chemical_list: D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008077:Lipoproteins, LDL; D011758:Pyrroles; D000069059:Atorvastatin