[Preparation of aminated porous resin and for bilirubin adsorption].
Polystyrene microspheres (PS) were successfully prepared by suspension polymerization processes. Chloroacetylated polystyrene has been prepared by Friedel-Crafts acetylation of PS with chloroacetyl chloride. In this report, carcinogenic compound (chloromethylether etc.) was avoided. The effects of solvent, catalyst, acylating agent and reaction time were studied. Novel adsorption resins were obtained by synthesis of chloroacetylated polystyrene with amine. The influences of solvent, amine reagent and reaction time on ion exchange capacity were investigated. Under the optimized reaction condition, the ion exchange capacity of the prepared resins was 4.1587 mmol/g. The maximum amount of adsorbed bilirubin was 30.85 mg/g, the adsorption percentage was 80%.
Xiao
Yuanpi
Y
National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, China.
Qu
Jianbo
J
Wang
Jiaxing
J
Ma
Guanghui
G
Zhao
Huiying
H
D000085:Acetates / Q000737:chemistry*; D000327:Adsorption; D000588:Amines / Q000737:chemistry; D001663:Bilirubin / Q000737:chemistry*; D006801:Humans; D008863:Microspheres; D011137:Polystyrenes / Q000138:chemical synthesis*; D016062:Porosity; D012117:Resins, Synthetic / Q000138:chemical synthesis* / Q000737:chemistry
D000085:Acetates; D000588:Amines; D011137:Polystyrenes; D012117:Resins, Synthetic; C045557:chloroacetyl chloride; D001663:Bilirubin