[Population data of five STRs from the INTERPOL series in a mestizo population of western Mexico (State of Jalisco)].
BACKGROUND
Short tandem repeats (STRs) are the DNA polymorphisms most widely used in forensic genetics and parentage testing. Most common series of STRs are those from FBI (CODIS) and from INTERPOL. While there are data related to the first group, no studies are still known in Mexican populations in regard of the INTERPOL set.


OBJECTIVE
To describe the genetic characteristics of five INTERPOL STRs and to estimate their main forensic parameters in a population from western Mexico.


METHODS
Samples from 100 random volunteers from the State of Jalisco were PCR typed for STRs F13B, D2S1338, FESFPS, Penta D and Penta E.


RESULTS
Genotype proportions in all five STRs were in agreement with Hardy-Weinberg expectations (p > 0.05). Heterocygosity varied from 0.68 for FESFPS to 0.91 for Penta E markers. Power of discrimination (PD) and exclusion probability (EP) were in the 0.83-0.97 and 0.46-0.75 ranges, respectively. The five combined STRs give a PE > 0.99143 and PD > 0.99999.


CONCLUSIONS
These results contribute to establish data bases representative of western Mexico and are useful in DNA forensic and parentage studies.
Quintero-Ramos
Antonio
A
Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social. antquintero@yahoo.com.mx
Padilla-Gutiérrez
Jorge R
JR
Hernández-Zaragoza
Guillermo
G
Valle
Yeminia
Y
Valdez-Velázquez
Laura L
LL
Olivares
Norma
N
Rivas
Fernando
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D000483:Alleles; D044383:Black People / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D005787:Gene Frequency; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D018895:Microsatellite Repeats; D008875:Middle Aged; D012494:Sampling Studies; D013030:Spain / Q000208:ethnology; D044465:White People / Q000235:genetics*; D055815:Young Adult
D005819:Genetic Markers