title: NMR assignment of the N-terminal TRAF-like RING zinc finger domain of human FLN29.
abstract: Resistance of cancer cells to oncotherapeutics designed to trigger programmed cell death (a.k.a. apoptosis) greatly limits clinical efficacy. The human FLN29 protein may play a role in this process via protein-protein interactions. Here we report the NMR spectral assignment of the N-terminal TRAF2/6-RING-zinc finger-like domain of this protein.
authors.affiliation: Centre for Biologics Research, Biologics and Genetic Therapies Directorate, Health Canada, 251 Sir Frederick Banting Driveway, A/L 2201E, Tunney's Pasture, Ottawa, ON, Canada.
authors.forename: Simon
authors.initials: S
authors.lastname: Sauvé
authors.forename: Geneviève
authors.initials: G
authors.lastname: Gingras
authors.forename: Rémy A
authors.initials: RA
authors.lastname: Aubin
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Hodgson
authors.forename: Yves
authors.initials: Y
authors.lastname: Aubin
mesh_terms: D000595:Amino Acid Sequence; D002247:Carbon Isotopes / Q000737:chemistry; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009587:Nitrogen Isotopes / Q000737:chemistry; D017434:Protein Structure, Tertiary; D011522:Protons; D054829:RING Finger Domains; D047988:Tumor Necrosis Factor Receptor-Associated Peptides and Proteins / Q000737:chemistry*
chemical_list: D002247:Carbon Isotopes; D047908:Intracellular Signaling Peptides and Proteins; D009587:Nitrogen Isotopes; D011522:Protons; C507622:TRAFD1 protein, human; D047988:Tumor Necrosis Factor Receptor-Associated Peptides and Proteins