HeartMate II implantation in patients with heparin-induced thrombocytopenia type II.
Diverse anticoagulation protocols are used in patients after implantation of ventricular assist devices. No consensus exists, especially in patients with heparin-induced thrombocytopenia type II. In a patient with heparin-induced thrombocytopenia type II, we implanted a left ventricular assist device (HeartMate XVE; Thoratec, Pleasanton, CA). Thirteen months later the device had to be replaced due to mechanical failure with a HeartMate II left ventricular assist device. We report on our successful protocol of perioperative anticoagulation management using heparin and iloprost during surgery and argatroban thereafter.
Meyer
Anna Lassia
AL
Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Malehsa
Doris
D
Kuehn
Christian
C
Bara
Christoph
C
Gras
Clemens
C
Hafer
Carsten
C
Haverich
Axel
A
Strüber
Martin
M
D000925:Anticoagulants / Q000009:adverse effects; D001120:Arginine / Q000031:analogs & derivatives; D002315:Cardiopulmonary Bypass; D004359:Drug Therapy, Combination; D006353:Heart-Assist Devices; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D016285:Iloprost / Q000008:administration & dosage; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010875:Pipecolic Acids / Q000008:administration & dosage; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D013449:Sulfonamides; D013921:Thrombocytopenia / Q000139:chemically induced; D014859:Warfarin / Q000008:administration & dosage
D000925:Anticoagulants; D010875:Pipecolic Acids; D010975:Platelet Aggregation Inhibitors; D013449:Sulfonamides; D014859:Warfarin; D006493:Heparin; D001120:Arginine; C031942:argatroban; D016285:Iloprost