title: Seasonal variation and bioactivity in the leaf oil of Liriodendron tulipifera growing in Huntsville, Alabama.
abstract: The seasonal variation in the chemical composition of the leaf essential oil of Liriodendron tulipifera has been analyzed by GC-MS. Two individual trees were sampled five times during the course of the growing season. Twenty components were identified in the leaf oils, which were dominated by sesquiterpene hydrocarbons, principally germacrene D and beta-elemene, in the early part of the season (42-44% and 18-23%, respectively,) but monoterpene hydrocarbons, largely (Z)-beta-ocimene, dominated the later season leaf oils (40-60%). The leaf oils exhibited in-vitro antibacterial activity against Bacillus cereus and Staphylococcus aureus as well as cytotoxic activity on MDA-MB-231 and Hs 578T human breast tumor cells.
authors.affiliation: Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Miller
authors.forename: Heather E
authors.initials: HE
authors.lastname: Villanueva
authors.forename: Maria C
authors.initials: MC
authors.lastname: Palazzo
authors.forename: Brenda S
authors.initials: BS
authors.lastname: Wright
authors.forename: William N
authors.initials: WN
authors.lastname: Setzer
mesh_terms: D000407:Alabama; D031567:Liriodendron / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*; D012621:Seasons
chemical_list: D010938:Plant Oils