Treatment of eyelid xanthelasma with 70% trichloroacetic acid.
OBJECTIVE
To analyze the results of treatment of eyelid xanthelasma (EX) with 70% trichloroacetic acid (TCA) with regard to efficacy, cosmetic appearance, patient satisfaction, and recurrence rate.


METHODS
Twenty-four patients with EX of up to one third of the affected palpebral area were treated with 70% TCA. All patients were photographed at the start of treatment and 3 months after the last application. The recurrence rate was analyzed at the end of 6 months of treatment.


RESULTS
The average number of applications of 70% TCA until the xanthelasma resolved was 1.5. Eleven patients (45.8%) had an excellent result, 8 (33.3%) a good result, and 5 (20.8%) had a satisfactory result. The most common complication was hypopigmentation (33.3%). All patients reported an improved final cosmetic result. Six patients (25%) treated with 70% TCA had a recurrence 6 months after treatment.


CONCLUSIONS
The results of prospective treatment of 24 patients with EX with 70% TCA indicated that this is a simple and effective method, achieves a satisfactory cosmetic result, has an acceptable recurrence rate, and high patient satisfaction.
Nahas
Tatiana Rizkallah
TR
Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil. tatinahas@uol.com
Marques
Junia Cabral
JC
Nicoletti
André
A
Cunha
Marcos
M
Nishiwaki-Dantas
Maria Cristina
MC
Filho
José Vital
JV
D000328:Adult; D000368:Aged; D002424:Caustics / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005141:Eyelid Diseases / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D017060:Patient Satisfaction; D011446:Prospective Studies; D016896:Treatment Outcome; D014238:Trichloroacetic Acid / Q000627:therapeutic use*; D014973:Xanthomatosis / Q000188:drug therapy* / Q000473:pathology
D002424:Caustics; D009883:Ophthalmic Solutions; D014238:Trichloroacetic Acid