title: [The peculiarities of epilepsy in the menopause].
abstract: Twenty seven cases with the combination of epilepsy and menopause are presented. The menopause proved to be a critical period for epilepsy manifestation: in 44.4% women with epilepsy the disease onset was observed at the peri- and post-menopause period. The course of epilepsy during this period was less severe: the frequency of seizures increased in 7.4% and decreased in 33.3%, no changes in the frequency of seizures were observed in 59.3%. The severity of menopause syndrome was not correlated with duration and severity of epilepsy, 81.4% of patients had the mild severity of this syndrome. The reduction of bone density was found in most of women (85.2%). It implies that all patients with epilepsy and menopause should receive a prophylactic treatment to prevent osteopenia. About 18.6% of patients required the hormone replacement therapy but only 7.4% received it due to adverse effects.
authors.forename: P N
authors.initials: PN
authors.lastname: Vlasov
authors.forename: M V
authors.initials: MV
authors.lastname: Antoniuk
authors.forename: N V
authors.initials: NV
authors.lastname: Orekhova
authors.forename: N D
authors.initials: ND
authors.lastname: Gasparian
authors.forename: N V
authors.initials: NV
authors.lastname: Dub
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008593:Menopause; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D000927:Anticonvulsants