title: [Preparation and characterization of nano-hydroxyapatite/polyurethane composite bio-film].
abstract: Through Hydroxyl (-OH) reacting with isocyanate group (-NCO), 13 Wt% nano-hydroxyapatite (n-HA)/polyurethane (PU) composite guided bone regeneration membrane was synthesized by use of solvent evaporation method. Its surface character was analyzed by XRD, IR, TG, contact angle, water absorption, elongation and combustion test and SEM. The results indicate that nano-HA/PU has good homogeneity,the interface between the inorganic mineral and organic polymer is optimized to create proper combination; that n-HA crystals are similar to the apatite crystals in natural bone, HA/PU composite membrane has good hydrophilicity mechanical behavior; and that many pores are observed on the membrane which help cells' metabolism. So the HA/PU composite membrane, thus prepared, has the potential for use in guided bone regeneration and tissue engineering.
authors.affiliation: Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Dong
authors.forename: Yubao
authors.initials: Y
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Qin
authors.initials: Q
authors.lastname: Zou
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D001861:Bone Regeneration; D017886:Durapatite / Q000737:chemistry*; D048091:Guided Tissue Regeneration / Q000379:methods*; D053761:Nanocomposites / Q000737:chemistry*; D011140:Polyurethanes / Q000737:chemistry*; D023822:Tissue Engineering / Q000379:methods; D054457:Tissue Scaffolds / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; D017886:Durapatite