Malignant transformation of a neurenteric cyst in the posterior fossa following complete excision.
We present a case of a 46-year-old man who developed malignant transformation of a neurenteric cyst felt to be completely removed 14 years previously. He re-presented with non-specific symptoms and hydrocephalus, and subsequent evidence of a complex lesion surrounding the lower brain stem and upper cervical cord. Histologically the original lesion was a benign neurenteric cyst, whereas the recurrent lesion showed a well differentiated adenocarcinoma. This is only the second case reported in the literature.
Surash
Surash
S
Department of Neurosurgery, The General Infirmary at Leeds, Leeds, UK. ssurash@mac.com
Ismail
Azzam
A
Loughrey
Carmel
C
van Hille
Philip
P
D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000628:therapy; D002530:Cerebellopontine Angle; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009436:Neural Tube Defects / Q000473:pathology* / Q000601:surgery