title: [Sarcoidosis with epididymal and testicular lesions: case report and a review of the literature].
abstract: A 47-year-old man was admitted for further examination of uveitis. He had noticed scrotal swelling before his admission. A computed tomographic scan of the chest showed hilar and mediastinal lymphadenopathy, multiple micronodules and thickening of the interlobular septum, and these findings were consistent with sarcoidosis. Bronchoalveolar lavage fluid showed lymphocytosis. Gallium-67 scintigraphy revealed an abnormal accumulation in the hilar and mediastinal lymph nodes and in the bilateral scrotum. The resected and biopsied specimens of the epididymis and testis demonstrated numerous noncaseating epithelioid cell granulomas but no evidence of neoplasm. Therefore, systemic sarcoidosis was diagnosed. A review of the Japanese literature found most cases to be associated with a history of painless scrotal swelling with chest roentgenogram findings of stage I or II, while also indicating it was important to perform biopsy or surgically resect any epididymal and testicular lesion.
authors.affiliation: Department of Respiratory Medicine (Internal Medicine 2), Oita University Hospital.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishii
authors.forename: Satoshi
authors.initials: S
authors.lastname: Otani
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Oka
authors.forename: Yuka
authors.initials: Y
authors.lastname: Amemiya
authors.forename: Atsuko
authors.initials: A
authors.lastname: Iwata
authors.forename: Kenji
authors.initials: K
authors.lastname: Umeki
authors.forename: Ryo
authors.initials: R
authors.lastname: Shirai
authors.forename: Kenji
authors.initials: K
authors.lastname: Kishi
authors.forename: Issei
authors.initials: I
authors.lastname: Tokimatsu
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kadota
mesh_terms: D000293:Adolescent; D004822:Epididymis / Q000473:pathology*; D006801:Humans; D008297:Male; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology*; D013737:Testis / Q000473:pathology*