title: Retinal vascular tumor and peripheral retinal vasculitis in the setting of systemic tuberculosis.
abstract: Tuberculosis commonly affects the eye by causing neovascularization, peripheral vasculitis, and choroidal tubercles. The authors describe a 28-year-old man with systemic tuberculosis who presented with a retinal vascular tumor, peripheral retinal vasculitis, retinal neovascularization, and vitreous hemorrhage causing acute vision loss. He was successfully treated with systemic anti-tuberculosis medications, retinal photocoagulation, and focal ablative diode laser to the tumor. Ophthalmologists should consider performing a purified protein derivative test and a chest x-ray for any patient with a history suspicious for tuberculosis who presents with a vascular tumor.
authors.affiliation: Bascom Palmer Eye Institute, Miami, FL 33136, USA.
authors.forename: Theodore
authors.initials: T
authors.lastname: Leng
authors.forename: Amy C
authors.initials: AC
authors.lastname: Schefler
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Murray
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005451:Fluorescein Angiography; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D017075:Laser Coagulation; D054023:Lasers, Semiconductor; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D009383:Neoplasms, Vascular Tissue / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D011718:Pyrazinamide / Q000627:therapeutic use; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D031300:Retinal Vasculitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D012293:Rifampin / Q000627:therapeutic use; D014374:Tuberculin Test; D014392:Tuberculosis, Ocular / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D014463:Ultrasonography
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin