title: Acetylcholinesterase inhibition and antioxidant activity of essential oils from Schinus areira L. and Schinus longifolia (Lindl.) Speg.
abstract: The essential oils of Schinus areira L. and S. longifolia (Lindl.) Speg. (Anacardiaceae) have been studied for their in vitro anti-acetylcholinesterase and antioxidant activities. The chemical composition of the oils obtained by hydrodistillation was determined by GC-MS. Fruit and leaf oils of S. areira were analyzed separately. The essential oil from S. longifolia elicited marked enzymatic inhibition (IC50 = 20.0 +/- 1.0 microg/mL) and showed radical scavenger activity (IC50 = 25.2 +/- 2.4 microg/mL). The essential oil from S. areira leaves was more active than that of the fruits in both bioassays.
authors.affiliation: Departamento de Química, Universidad Nacional del Sur, Av. Alem 1253, B8000CPB Bahía Blanca, Argentina. apmurray@uns.edu.ar
authors.forename: Ana P
authors.initials: AP
authors.lastname: Murray
authors.forename: Maria S Vela
authors.initials: MS
authors.lastname: Gurovic
authors.forename: Silvana A
authors.initials: SA
authors.lastname: Rodriguez
authors.forename: María G
authors.initials: MG
authors.lastname: Murray
authors.forename: Adriana A
authors.initials: AA
authors.lastname: Ferrero
mesh_terms: D027926:Anacardiaceae / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D009822:Oils, Volatile; D010938:Plant Oils