title: A conventional route to scalable morphology-controlled regular structures and their superhydrophobic/hydrophilic properties for biochips application.
abstract: We use a conventional and straightforward route to fabricate scalable morphology-controlled regular structures. This route is based on the etching of PDMS microlens array in CF4 and CF4/O2 plasma. PDMS microlens array can be changed to regularly isolated microdot structures array in CF4 plasma. Microbowl shaped structures array can be reached in CF4/O2 plasma. Moreover, a set of structures after CF4 plasma treatment display superhydrophobicity, while a set of structures after CF4/O2 plasma treatment present hydrophilicity. DNA molecules can be readily enriched on the hydrophilic surface. We believe that the regular structure array surfaces provide a useful inspiration towards biomolecular detection and transportation in biochips.
authors.affiliation: School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210098, PR China.
authors.forename: Hong-Xuan
authors.initials: HX
authors.lastname: Ren
authors.forename: Xing
authors.initials: X
authors.lastname: Chen
authors.forename: Xing-Jiu
authors.initials: XJ
authors.lastname: Huang
authors.forename: Maesoon
authors.initials: M
authors.lastname: Im
authors.forename: Dong-Haan
authors.initials: DH
authors.lastname: Kim
authors.forename: Joo-Hyung
authors.initials: JH
authors.lastname: Lee
authors.forename: Jun-Bo
authors.initials: JB
authors.lastname: Yoon
authors.forename: Ning
authors.initials: N
authors.lastname: Gu
authors.forename: Jin-Huai
authors.initials: JH
authors.lastname: Liu
authors.forename: Yang-Kyu
authors.initials: YK
authors.lastname: Choi
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004277:DNA, Single-Stranded / Q000032:analysis; D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D007909:Lenses; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D010100:Oxygen / Q000737:chemistry; D017155:Wettability
chemical_list: D004277:DNA, Single-Stranded; D004129:Dimethylpolysiloxanes; D006845:Hydrocarbons, Fluorinated; C013830:baysilon; C538689:tetrafluoromethane; D010100:Oxygen