Cutaneous and systemic plasmacytosis in an Asian male born in the North American continent: a controversial entity potentially related to multicentric Castleman disease.
Cutaneous and systemic plasmacytosis is a rare condition primarily affecting middle-aged individuals of Japanese descent and has principally been reported in cases originating from Asia. Its relationship, if any, to Castleman disease, is controversial. The authors report a case of cutaneous and systemic plasmacytosis involving a 36-year-old man of Chinese ancestry born in North America. The biopsy of an involved lymph node revealed changes resembling Castleman disease. Significantly, this case to our knowledge represents the first case of cutaneous and systemic plasmacytosis presenting in a patient of Chinese ancestry born on the North American mainland.
Shadel
Brooke N
BN
Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO 63104, USA.
Frater
John L
JL
Gapp
Joshua D G
JD
Hurley
M Yadira
MY
D000328:Adult; D044466:Asian People; D005871:Castleman Disease / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D010950:Plasma Cells / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*