Seroprevalence of human granulocytotropic anaplasmosis in central and southeastern China.
Human granulocytic anaplasmosis (HGA) is an emerging tick-borne infectious disease. To determine the prevalence of HGA in central and southeastern China, a total of 323 human sera were collected from individuals at high risk for exposure to ticks and animals. The IgG antibody against the etiologic agent of HGA, Anaplasma phagocytophilum was detected with indirect immunofluorescence assay. The results showed that 20% of the tested individuals (64/323) were positive to A. phagocytophilum and that the incidence was higher in male (22%) than female (16%). We concluded that A. phagocytophilum infection was prevalent in central and southeastern China.
Zhang
Shouyin
S
State Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China.
Hai
Rong
R
Li
Wenyuan
W
Li
Guohua
G
Lin
Guangyu
G
He
Jinrong
J
Fu
Xiuping
X
Zhang
Jingshan
J
Cai
Hong
H
Ma
Fengqin
F
Zhang
Jianhua
J
Yu
Dongzheng
D
Yu
Xue-Jie
XJ
D000328:Adult; D017677:Age Distribution; D041081:Anaplasma phagocytophilum / Q000276:immunology; D000907:Antibodies, Bacterial / Q000097:blood; D002681:China / Q000453:epidemiology; D016873:Ehrlichiosis / Q000453:epidemiology*; D005260:Female; D006098:Granulocytes / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D055815:Young Adult
D000907:Antibodies, Bacterial