[Two diterpenoids from herbs of Huperzia serrata].
OBJECTIVE
To investigate the constituents from Huperzia serrata.


METHODS
Two diterpenoid compounds were isolated by column chromatography with silica gel and Sephadex LH-20. The structures were elucidated by spectral analysis and X-ray crystallographic analysis.


RESULTS
Their structures were determined as (15R)-12, 16-epoxy-11, 14-dihydroxy-8, 11, 13-abietatrien-7-one (1) and 3beta-hydroxysandaracopimaric acid (2).


CONCLUSIONS
Compound 1 was a new natural abietane-type diterpenoid, compound 2 was isolated from this plant for the first time.
Yang
Yabin
Y
Key laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
Yang
Xueqiong
X
Xu
Yanqun
Y
Tai
Zhigang
Z
Dong
Liuhong
L
Ding
Zhongtao
Z
D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000032:analysis / Q000737:chemistry*; D032501:Huperzia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D004224:Diterpenes