title: [Analysis of flavonoids in Rhododendron mariae by UPLC/ Q-TOF-MS].
abstract: OBJECTIVE
  To investigate the flavonoids in Rhododendron mariae.
  
  
  METHODS
  The constituents in R. mariae were determined by UPLC/Q-TOF-MS. The chromatographic separation was performed on a C18 column (2.1 mm x 50 mm, 1.7 microm) with a gradient elufion of methanol-water containing 0.1% formic acid. The mass specfrometer eqaipped with elecfrospay ionizafion source was usedas defecfor and operated in data was collected under the positive and negative ion modes.
  
  
  RESULTS
  Seven constituents were identified as myricetin-3-O-beta-D-gluconside (1), myricetin-3'-O-beta-D-xylopyraoside (2), hyperoside (3), isoquercitrin (4), avicularin (5), quercitroside (6) and quercetin (7).
  
  
  CONCLUSIONS
  In this study, the main flavonoids in R. mariae were separated by UPLC, and identified through the information of positive ion and negative ion and relative molecular mass which were determined by Q-TOF-MS. It is an accurate and effective method which can be applied for the constituent identification of R. mariae.
authors.affiliation: Central Laboratory of Guangdong Pharmaceutical University, Guangzhou 510006, China. hhqwxh@163.com
authors.forename: Huiqiang
authors.initials: H
authors.lastname: Huang
authors.forename: Yifan
authors.initials: Y
authors.lastname: Feng
authors.forename: Wen
authors.initials: W
authors.lastname: Rui
authors.forename: Miaomiao
authors.initials: M
authors.lastname: Jiang
authors.forename: Liang
authors.initials: L
authors.lastname: Han
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000032:analysis* / Q000737:chemistry; D013058:Mass Spectrometry; D029793:Rhododendron / Q000737:chemistry*
chemical_list: D005419:Flavonoids