title: [Hypoxic ischemic encephalopathy with atypical findings on CT and MR imaging: two case reports].
abstract: We report 2 cases of hypoxic ischemic encephalopathy with atypical findings on computed tomographic (CT) and magnetic resonance (MR) imaging for the acute to subacute stage. Case 1: A 78-year-old man with larynx cancer suffered cardiac arrest after suffocation. Cardiopulmonary resuscitation, was performed; the patient then went into a deep coma and also developed severemyoclonus. CT scans on day 0 and day 3 after the arrest revealed no abnormalities MR imaging was performed on day 13 to evaluate cerebral anoxia; however, no abnormal findings were obtained. Since no abnormalities were detected both on CT and MR imaging, we expected that the prognosis would be good; however, the patients did not recover from coma and remains in a persistent vegetative state. Case 2: A 54-year-old man developed cardiac arrest after anaphylactic shock caused by insect bite. After cardiopulmonary resuscitation, the patient lapsed into a deep coma. CT scans performed on day 1 and 3 after the cardiac arrest revealed slight subarachnoid hemorrhage at the surface of the right cerebral cortex along the falx cerebri. MR images obtained on day 10 demonstrated slight hemorrhage at the surface of right cerebral cortex, but no abnormalities in basal ganglia, thalamus, cortex, and white matter. The transient damage of the blood brain barrier caused by hypoxia and ischemia was thought to induce the slight subarachnoid hemorrhage after cardiopulmonary resuscitation. The patient demonstrated early recovery and was almost completely recovered with slight agnosia. MR imaging to rule out hypoxic-ischemic encephalopathy may not have been timed appropriately in both the case, our radiological findings are usual as compare to the findings presented in other similar reports. The variations in the findings of CT and MR imaging in the case of hypoxic-ischemic encephalopathy should be clarified, and the prognosis and management of this condition should be planned on the basis of not only the neuroradiological images but also the neurological signs and symptoms.
authors.affiliation: Department of Neurosurgery, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan.
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Arishima
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Hosoda
authors.forename: Norichika
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Yuji
authors.initials: Y
authors.lastname: Handa
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Kubota
authors.forename: Ryuuji
authors.initials: R
authors.lastname: Suzuki
authors.forename: Hironobu
authors.initials: H
authors.lastname: Tokunaga
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kimura
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Terasawa
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed