Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA.
Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by (1)H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies. The relative rates of singlet-oxygen production from the diselenide-linked porphyrin dimers upon photoirradiation were also measured.
Xue
Zhi
Z
Department of Chemistry, Wuhan University, Wuhan, P. R. China.
Kwong
Daniel Wei-Jing
DW
Xue
Ling-Wei
LW
Liu
Qing
Q
Hou
An-Xin
AX
Wong
Wai-Kwok
WK
D002384:Catalysis; D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D010084:Oxidation-Reduction; D011166:Porphyrins / Q000138:chemical synthesis* / Q000737:chemistry; D012643:Selenium / Q000737:chemistry*; D026082:Singlet Oxygen / Q000737:chemistry
D011166:Porphyrins; D026082:Singlet Oxygen; D004247:DNA; D012643:Selenium