title: Eczema herpeticum and clinical criteria for investigating smallpox.
abstract: Eczema herpeticum can clinically resemble smallpox. On the basis of the algorithm for rapid evaluation of patients with an acute generalized vesiculopustular rash illness, our patient met criteria for high risk for smallpox. The Tzanck preparation was critical for rapid diagnosis of herpetic infection and exclusion of smallpox.
authors.affiliation: Department of Dermatology, Naval Hospital Jacksonville, Jacksonville, Florida 32214, USA. s2d2boyd@yahoo.com
authors.forename: David A
authors.initials: DA
authors.lastname: Boyd
authors.forename: Leonard C
authors.initials: LC
authors.lastname: Sperling
authors.forename: Scott A
authors.initials: SA
authors.lastname: Norton
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000821:virology*; D003937:Diagnosis, Differential; D014645:Herpesvirus 3, Human / Q000302:isolation & purification; D006801:Humans; D007617:Kaposi Varicelliform Eruption / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D018139:Simplexvirus / Q000302:isolation & purification; D012899:Smallpox / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir