title: Update on the management of keloids.
abstract: Keloids are scars, unique to humans, that grow beyond the boundaries of a cutaneous injury, inflammation, burn, or surgical incision. Although benign, keloids are often aesthetically malignant. The etiology of keloids is uncertain. However, we do know that they occur more often in African-American and Asian than Caucasian patients. There is no one therapeutic modality that either prevents the formation of keloids or treats active or inactive lesions. Consequently, there are many therapeutic options. In this review, an approach to medical and surgical management of keloids is provided, as well as a review of experimental therapeutic modalities.
authors.affiliation: Department of Internal Medicine, Division of Dermatology, Charles Drew University of Medicine and Science, Los Angeles, CA 90059-3019, USA.
authors.forename: A Paul
authors.initials: AP
authors.lastname: Kelly
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001741:Black or African American; D000634:Aminoquinolines / Q000627:therapeutic use; D003452:Cryosurgery; D006801:Humans; D000077271:Imiquimod; D015552:Injections, Intralesional; D007627:Keloid / Q000188:drug therapy / Q000208:ethnology* / Q000601:surgery / Q000628:therapy*; D053685:Laser Therapy
chemical_list: D000276:Adjuvants, Immunologic; D000305:Adrenal Cortex Hormones; D000634:Aminoquinolines; D000077271:Imiquimod