Ovarian hyperstimulation secondary to ectopic secretion of follicle-stimulating hormone. Literature review prompted by a case.
OBJECTIVE
To present an exceptional clinical case of functional follicle-stimulating gonadotropin secretion by a thorax neuroendocrine carcinoid tumor.


METHODS
Case report.


METHODS
Department of Obstetrics and Gynecology, Cruces University Hospital, Vizcaya, Spain.


METHODS
A 26-year-old woman with ovarian hyperstimulation.


METHODS
Diagnosis algorithm.


METHODS
Successful management of ovarian hyperstimulation.


RESULTS
A 26-year-old woman seen with abdominal pain and swelling had bilateral multicystic ovaries. The diagnosis algorithm revealed the presence of ovarian hyperstimulation but with no due etiology. On the basis of the persistence of high levels of FSH a computed tomographic scan was taken looking for an FSH-producing neuroendocrine tumor.


CONCLUSIONS
In idiopathic ovarian hyperstimulation secondary to supraphysiologic secretion of FSH, the presence of an FSH-producing neuroendocrine tumor should be considered. As far as we know, there are no similar cases with a confirmed diagnosis published in the literature.
Burgos
Jorge
J
Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain; School of Medicine, Universidad del País Vasco, Vizcaya, Spain. Electronic address: jburgoss@sego.es.
Cobos
Patricia
P
Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
Vidaurrazaga
Nerea
N
School of Medicine, Universidad del País Vasco, Vizcaya, Spain; Department of Anatomopathology, Hospital de Cruces, Vizcaya, Spain.
Prieto
Begoña
B
Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
Ocerin
Iratxe
I
School of Medicine, Universidad del País Vasco, Vizcaya, Spain; Endoscopy Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain.
Matorras
Roberto
R
Human Reproduction Unit, Department of Obstetrics and Gynecology, Hospital de Cruces, Vizcaya, Spain; School of Medicine, Universidad del País Vasco, Vizcaya, Spain.
D000328:Adult; D002276:Carcinoid Tumor / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006801:Humans; D016471:Ovarian Hyperstimulation Syndrome / Q000175:diagnosis* / Q000209:etiology*; D013899:Thoracic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D005640:Follicle Stimulating Hormone