Innate immunity: wounds burst H2O2 signals to leukocytes.
How leukocytes are attracted to wounds is poorly understood. Recent work using zebrafish reveals a novel mechanism of early leukocyte recruitment to wounds through a concentration gradient of hydrogen peroxide.
Yoo
Sa Kan
SK
Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Huttenlocher
Anna
A
D000818:Animals; D006861:Hydrogen Peroxide / Q000378:metabolism*; D007113:Immunity, Innate / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology / Q000378:metabolism*; D016897:Respiratory Burst / Q000502:physiology*; D014945:Wound Healing / Q000276:immunology*; D015027:Zebrafish
D006861:Hydrogen Peroxide