Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results.
In this study, the expression of chemokine receptors on the surface of circulating leukocytes was determined using flow cytometry. An increase in the percentage of CCR2+CD4+ lymphocytes was observed in the peripheral blood of leprosy patients. This preliminary data suggests that alterations occur in the chemokine receptor profile of these patients.
Mendonça
Vanessa Amaral
VA
Federal University of the Jequitinhonha and Mucuri Valleys, MG, Brazil. vaafisio@hotmail.com
Melo
Gustavo Eustáquio Brito Alvim de
GE
Teixeira
Mauro Martins
MM
Martins-Filho
Olindo Assis
OA
Antunes
Carlos Maurício
CM
Teixeira
Antonio Lúcio
AL
D016022:Case-Control Studies; D005434:Flow Cytometry; D006801:Humans; D007918:Leprosy / Q000097:blood*; D007962:Leukocytes / Q000737:chemistry*; D054390:Receptors, CCR2 / Q000097:blood*; D019713:Receptors, CCR5 / Q000097:blood*; D019718:Receptors, CXCR4 / Q000097:blood*
D054390:Receptors, CCR2; D019713:Receptors, CCR5; D019718:Receptors, CXCR4