title: Electroencephalogram and heart rate regulation to familiar and unfamiliar people in children with autism spectrum disorders.
abstract: Few studies have examined whether familiarity of partner affects social responses in children with autism. This study investigated heart rate regulation (respiratory sinus arrhythmia [RSA]: The myelinated vagus nerve's regulation of heart rate) and temporal-parietal electroencephalogram (EEG) activity while nineteen 8- to 12-year-old children with autism and 14 controls viewed videos of a familiar and an unfamiliar person reading a story. Children with autism had lower overall RSA levels and exhibited decreased RSA to the unfamiliar person, versus control children. Both groups decreased temporal-parietal EEG activity to the unfamiliar person. Higher RSA was related to higher social skill ratings and fewer problem behaviors. Thus, the social difficulties of children with autism may be characterized by specific mobilization to unfamiliar people.
authors.affiliation: Marquette University, P.O. Box 1881, Milwaukee, WI 53201-1881, USA. vanhecke@marquette.edu
authors.forename: Amy
authors.initials: A
authors.lastname: Vaughan Van Hecke
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Lebow
authors.forename: Elgiz
authors.initials: E
authors.lastname: Bal
authors.forename: Damon
authors.initials: D
authors.lastname: Lamb
authors.forename: Emily
authors.initials: E
authors.lastname: Harden
authors.forename: Alexis
authors.initials: A
authors.lastname: Kramer
authors.forename: John
authors.initials: J
authors.lastname: Denver
authors.forename: Olga
authors.initials: O
authors.lastname: Bazhenova
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Porges
mesh_terms: D001321:Autistic Disorder; D002648:Child; D004569:Electroencephalography; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D010296:Parietal Lobe / Q000502:physiology*; D012919:Social Behavior; D012938:Social Perception; D013702:Temporal Lobe / Q000502:physiology*; D014743:Videotape Recording