title: Temperature-dependent vesicle response to surface topography.
abstract: We have examined the deformation of vesicles on surface topography. From known vesicle shape dynamics, we expect temperature to play a major role; however, when cooling vesicles in the presence of a low-permeability solute, the mechanism of deflation is not clear. We investigate giant unilamellar vesicles on topography to quantify their cooling over a range of temperatures. The volume constraints point to a transient defect pore model as being responsible for vesicle deflation over the temperature range studied.
authors.affiliation: Department of Chemistry, George Washington University, 725 21st Street, N.W., Washington, DC 20052, USA. sdgill@gwu.edu
authors.forename: Susan D
authors.initials: SD
authors.lastname: Gillmor
authors.forename: Julia J
authors.initials: JJ
authors.lastname: Heetderks
authors.forename: Paul S
authors.initials: PS
authors.lastname: Weiss