title: Surface modification of and selective protein attachment to a flexible microarray pattern using atmospheric plasma with a reactive gas.
abstract: The hydrophobic and hydrophilic properties of the surface of poly-ether sulfone (PES) films were controlled by an atmospheric pressure plasma (AP) treatment using reactive gases (Ar/H(2) and Ar/O(2)). The surface properties of the Ar/H(2) and Ar/O(2) in series AP-treated PES films showed higher surface roughness (approximately 120%), surface energy (approximately 30%) and hydrophilic properties (oxygen content approximately 10%) than the Ar/O(2) AP-treated PES film. The protein staining results confirmed that an activated region on the patterned PES film with high selectivity and sensitivity was well-defined and formed. This method is suitable for fabricating flexible protein adhesive chips with uniform biomolecular adhesive properties.
authors.affiliation: College of Nanoscience and Nanotechnology, Pusan National University, Busan, Republic of Korea.
authors.forename: Hyun-Uk
authors.initials: HU
authors.lastname: Lee
authors.forename: So-Young
authors.initials: SY
authors.lastname: Park
authors.forename: Yoon-Hee
authors.initials: YH
authors.lastname: Kang
authors.forename: Se-Young
authors.initials: SY
authors.lastname: Jeong
authors.forename: Sae-Hae
authors.initials: SH
authors.lastname: Choi
authors.forename: Kwang-Yeop
authors.initials: KY
authors.lastname: Jahng
authors.forename: Chae-Ryong
authors.initials: CR
authors.lastname: Cho
mesh_terms: D001274:Atmospheric Pressure; D040081:Protein Array Analysis; D011506:Proteins / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D011506:Proteins