Establishment of reference values of CD4 and CD8 lymphocyte subsets in healthy Nigerian adults.
A total of 2,570 apparently healthy human immunodeficiency virus-negative adults from the six geopolitical zones in the country were enrolled in our study in 2006. The samples were assayed using the Cyflow technique. Data were analyzed using the Statistical Package for Social Scientists (SPSS). The majority (64%) of the participants had CD4 counts within the range of 501 to 1,000 cells/microl. The reference range for CD4 was 365 to 1,571 cells/microl, while the reference range for CD8 was 145 to 884 cells/microl.
Oladepo
D K
DK
National Institute for Pharmaceutical Research and Development, Garki, Abuja, Nigeria. daudaoladepo@yahoo.com
Idigbe
E O
EO
Audu
R A
RA
Inyang
U S
US
Imade
G E
GE
Philip
A O
AO
Okafor
G O
GO
Olaleye
D
D
Mohammed
S B
SB
Odunukwe
N N
NN
Harry
T O
TO
Edyong-Ekpa
M
M
Idoko
J
J
Musa
A Z
AZ
Adedeji
A
A
Nasidi
A
A
Ya'aba
Y
Y
Ibrahim
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018791:CD4 Lymphocyte Count; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D016131:Lymphocyte Subsets / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D055815:Young Adult