title: Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle.
abstract: OBJECTIVE
  Poor growth has been described in infants with a single ventricle; however, little is known regarding its effect on surgical outcomes. We sought to assess the effect of nutritional status at the time of the bidirectional Glenn procedure on short-term outcomes.
  
  
  METHODS
  We performed a retrospective case series of children who underwent the bidirectional Glenn procedure at our institution between January 2001 and December 2007. Anthropometric measurements were recorded at the time of neonatal admission and the bidirectional Glenn procedure. Data from preoperative echocardiograms and cardiac catheterization were recorded. The primary outcome variable was length of hospital stay.
  
  
  RESULTS
  Data on 100 infants were included for analysis. Age at the time of the bidirectional Glenn procedure was 5.1 months (range, 2.4-10 months). The median weight-for-age z score at birth was -0.4 (range, -2.6 to 3.2), and by the time of the bidirectional Glenn procedure, it had decreased to -1.3 (range, -3.9 to 0.6). In multivariable modeling longer postoperative hospital stays were predicted by lower weight-for-age z score (P = .02), younger age (P < .001), being fed through a gastrostomy tube (P = .01), and undergoing concomitant aortic arch reconstruction (P < .001) at the time of the bidirectional Glenn procedure.
  
  
  CONCLUSIONS
  There is suboptimal weight gain between neonatal discharge and the bidirectional Glenn procedure. A lower weight-for-age z score and younger age at the time of the bidirectional Glenn procedure affects length of hospital stay independent of hemodynamic or echocardiographic variables.
authors.affiliation: Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45259, USA. jeffrey.anderson@cchmc.org
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Anderson
authors.forename: Robert H
authors.initials: RH
authors.lastname: Beekman
authors.forename: William L
authors.initials: WL
authors.lastname: Border
authors.forename: Heidi J
authors.initials: HJ
authors.lastname: Kalkwarf
authors.forename: Philip R
authors.initials: PR
authors.lastname: Khoury
authors.forename: Karen
authors.initials: K
authors.lastname: Uzark
authors.forename: Pirooz
authors.initials: P
authors.lastname: Eghtesady
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Marino
mesh_terms: D000886:Anthropometry; D001011:Aorta / Q000601:surgery; D001724:Birth Weight; D001835:Body Weight; D013504:Cardiovascular Surgical Procedures; D015505:Chest Tubes; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery; D006352:Heart Ventricles / Q000002:abnormalities*; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D009752:Nutritional Status; D018529:Nutritional Support; D011183:Postoperative Complications; D012121:Respiration, Artificial