Synthesis of chiral fluorine-tagged reference standards for the (19)F NMR-based stereochemical analysis of sulfoxides at trace analytical levels.
Chiral fluorine-tagged sulfoxides of known absolute configuration have been synthesized. These compounds are required as reference standards to validate a (19)F NMR-based micromethod for the stereochemical analysis of biosynthetic fatty acyl sulfoxides.
Tremblay
Amy E
AE
Ottawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, Canada.
Lao
Kim Y Y
KY
Hodgson
Derek J
DJ
Dawson
Brian
B
Buist
Peter H
PH
D005461:Fluorine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D012015:Reference Standards; D013237:Stereoisomerism; D013454:Sulfoxides / Q000138:chemical synthesis / Q000737:chemistry*
D013454:Sulfoxides; D005461:Fluorine