A new labdane diterpene from Vitex cauliflora Moldenke from the Madagascar rainforest.
Fractionation of an antiplasmodial ethanolic extract from the aerial parts of Vitex cauliflora led to the isolation of the new labdane diterpene 1 together with the known triterpene uvaol. The structure of the new compound 1 was established as 3-oxo,15,17,18-triacetoxy-labda-7,13E-diene on the basis of spectroscopic data (1D and 2D NMR, MS).
Rasamison
Vincent E
VE
Centre National d'Application des Recherches Pharmaceutiques, B.P. 702, Antananarivo 101, Madagascar.
Ranaivo-Harimanana
Leon
L
Cao
Shugeng
S
Pan
Ende
E
Ratovoson
Fidy
F
Randriantafika
F
F
Rakotondrajaona
R
R
Rakotonandrasana
Stephan
S
Andriantsiferana
Rabodo
R
Kingston
David G I
DG
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008270:Madagascar; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010963:Plasmodium falciparum / Q000187:drug effects; D020950:Vitex / Q000737:chemistry*
D004224:Diterpenes