title: Rhenium-catalyzed addition of carbonyl compounds to the carbon-nitrogen triple bonds of nitriles: alpha-C-H activation of carbonyl compounds.
abstract: The ReH(7)(PPh(3))(2)-catalyzed addition of carbonyl compounds to the carbon-nitrogen bond of nitriles proceeds efficiently and selectively to give the corresponding (Z)-enamines, which are important synthetic intermediates. The key step of the reaction is the chemoselective alpha-C-H activation of carbonyl compounds induced by the alpha-heteroatom effect in the presence of nitriles.
authors.affiliation: Department of Chemistry, Graduate School of Engineering Science, Osaka University, Machikaneyama, 1-3, Toyonaka, Osaka, 560-8531, Japan.
authors.forename: Hikaru
authors.initials: H
authors.lastname: Takaya
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Ito
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Murahashi