Neointimal hyperplasia in a thin-strut cobalt-chromium stent: insights from detailed 3-D intravascular ultrasound analysis.
The effect of current generation cobalt-chromium stents on neointimal proliferation has not been fully elucidated. IVUS images of 137 patients treated with a single thin-strut cobalt-chromium stent (Driver: DRI, n=74) or stainless steel stent (Multilink plus: ML, n=63) were selected. Although % neointima volume (neointimal volume divided by stent volume) were comparable, DRI showed significantly smaller maximum %cross-sectional narrowing (%CSN: neointimal area divided by stent area) (P=0.006) with significantly less %CSN>60 (percent stent length with %CSN>60%) than ML (P=0.04). In conclusion, the amount of neointimal hyperplasia after DRI implantation was comparable to that after ML. However, current generation cobalt-chromium DRI may show less and shorter severe narrowing than the stainless steel ML.
Otake
Hiromasa
H
Ako
Junya
J
Waseda
Katsuhisa
K
Sakurai
Ryota
R
Hirohata
Atsushi
A
Kaneda
Hideaki
H
Hasegawa
Takao
T
Honda
Yasuhiro
Y
Fitzgerald
Peter J
PJ
D000368:Aged; D002857:Chromium; D003035:Cobalt; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D008875:Middle Aged; D058426:Neointima / Q000000981:diagnostic imaging* / Q000473:pathology; D015607:Stents / Q000009:adverse effects; D018084:Ultrasonography, Interventional / Q000379:methods
D002857:Chromium; D003035:Cobalt