title: Reproducibility of same session repeated cystometry and pressure-flow studies in women with symptoms of urinary incontinence.
abstract: OBJECTIVE
  The aim of this study was to determine the reproducibility of same session repeated urodynamic measurements in women with symptoms of urinary incontinence.
  
  
  METHODS
  Women presenting with symptoms of urinary incontinence underwent standardized urodynamic examination, which consisted of free uroflowmetry and two filling cystometries and pressure-flow studies. Intra-class Correlation Coefficient (ICC) and McNemar tests were used to describe the same session reproducibility.
  
  
  RESULTS
  Two evaluable urodynamic tests were available in 152 patients. Overall, reproducibility of the urodynamic parameters were good to excellent (ICC range: 0.72-0.93), except for the bladder volume at first sensation of bladder filling (ICC = 0.46) and the maximum Watt's factor (ICC = 0.68). The bladder volume at first sensation and the maximum cystometric capacity were systematically higher in the second run (mean difference (95% CI) = -45 (-73; -37) and -3 (-15; 10), respectively). Reproducibility of the diagnosis stress urinary incontinence and/or detrusor overactivity were good to excellent (median ICC = 0.76, P = 0.68 and P = 1.00, respectively). Reproducibility of the volume and amplitude at involuntary detrusor contractions, however, were only poor (ICC = 0.18 and 0.25, respectively).
  
  
  CONCLUSIONS
  The reproducibility of same session repeated urodynamic measurements in women with symptoms of urinary incontinence was good to excellent. Our results provide the scientific support for guidelines that recommend the omission of repeated filling cystometries and pressure-flow studies in cases where the first test confirms the pathology expected.
authors.affiliation: Department of Obstetrics & Gynecology 791, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. s.broekhuis@obgyn.umcn.nl
authors.forename: Suzan R
authors.initials: SR
authors.lastname: Broekhuis
authors.forename: Kirsten B
authors.initials: KB
authors.lastname: Kluivers
authors.forename: Jan C M
authors.initials: JC
authors.lastname: Hendriks
authors.forename: Elske T
authors.initials: ET
authors.lastname: Massolt
authors.forename: Jan
authors.initials: J
authors.lastname: Groen
authors.forename: Mark E
authors.initials: ME
authors.lastname: Vierhout
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D011312:Pressure; D015203:Reproducibility of Results; D014549:Urinary Incontinence / Q000175:diagnosis / Q000503:physiopathology*; D014563:Urodynamics