Evaluation of IFN-gamma serum level in nephropatic type 2 diabetic patients.
The present study was aimed to examine the serum level of IFN-gamma in type 2 diabetic patients with nephropatic complications. In this experimental study, serum samples were obtained from 100 type 2 diabetic patients suffering from nephropathy and 100 healthy controls. Serum level of IFN-gamma was analyzed by ELISA. Results of this study showed that the mean serum level of IFN-gamma was 16.09 +/- 2.04 and 4.03 +/- 1.00 pg mL(-1) in nephropathic patients and healthy controls, respectively. Statistical analysis of data showed that the difference in the IFN-gamma serum level was significant between nephropathic patients and controls. Due to the elevated level of IFN-gamma in nephropathic patients, it can be possibly concluded that IFN-gamma is involved in nephropathy complication of type 2 diabetes.
Nosratabadi
Reza
R
Department of Laboratory Sciences, Faculty of Medicine, Islamic Azad University, Zahedan Branch, Zahedan, Iran.
Arababadi
M K
MK
Hassanshahi
G
G
Yaghini
N
N
Pooladvand
V
V
Shamsizadeh
Ali
A
Zarandi
E R
ER
Hakimi
H
H
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications* / Q000276:immunology; D003928:Diabetic Nephropathies / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood*; D008297:Male; D008875:Middle Aged
D007371:Interferon-gamma