title: Micronutrients and amino acids, main regulators of physiological processes.
abstract: Human physiology is supposed to be a complex interaction of regulating processes, in which hormones, genes, their proteins and apoptosis are thought to play a dominant role. We hypothesize that regulation of physiological processes is mainly influenced by amino acids and micronutrients with hormones, proteins, apoptosis and gene modifications being their derivatives. Furthermore, we suppose that the cells power plant, the mitochondrion, is in fact an intracellular bacterium, living in absolute symbiosis. Because of its intracellular existence it depends on the host's micronutrients completely. Within the host these micronutrients regulate their own formation, degradation, uptake and excretion. Known deficiencies, such as iodine and vitamin D, affect billions of people. Many micronutrients neither have been investigated, nor have they been studied in relation to each other and solid data are not available. Optimal levels of many micronutrients and all amino acids are not known. Amino acids, vitamins and minerals are capable of altering gene expression, inducing apoptosis and regulating chemical processes. It makes them highly attractive for creating better health, against low cost, as we have already proven in the case of rickets, cretinism and scurvy in severe deficiencies. By creating optimal living conditions and study mitochondria from a symbiotic point of view we suppose that diseases not only can be prevented, but the course of diseases can be altered as well.
authors.affiliation: Regionaal Reuma Centrum Z.O. Brabant, Máxima Medisch Centrum, Ds. Th. Fliednerstraat 1, 5631 BM Eindhoven, Netherlands. rh.verheesen@mmc.nl
authors.forename: R H
authors.initials: RH
authors.lastname: Verheesen
authors.forename: C M
authors.initials: CM
authors.lastname: Schweitzer
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D002468:Cell Physiological Phenomena; D005246:Feedback / Q000502:physiology; D005502:Food; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D008954:Models, Biological
chemical_list: D000596:Amino Acids