Klebsiella pneumoniae clinical isolate coproducing SHV-2a, DHA-1, QnrB4, and AAC(6')-Ib-cr determinants in France.
We report on a Klebsiella pneumoniae clinical isolate coproducing bla(DHA-1), bla(SHV-2a), qnrB4, and aac(6')-Ib-cr genes. Molecular analysis demonstrated the presence of this combination on the same large plasmid. Despite a negative result for extended-spectrum beta-lactamase (ESBL) by Vitek2(R) system (bioMérieux, Marcy-l'Etoile, France), an ESBL was detected by a double-disk test. Phenotypic techniques and molecular analysis are key approaches to determine coresistance.
Corvec
Stéphane
S
Service de Bactériologie-Hygiène Hospitalière, CHU de Nantes, 9 quai Moncousu, 44093 Nantes Cedex 01, France. stephane.corvec@chu-nantes.fr
Crémet
Lise
L
Caroff
Nathalie
N
Dauvergne
Sandie
S
Le Floch
Ronan
R
Reynaud
Alain
A
Lepelletier
Didier
D
Bémer
Pascale
P
D024881:Drug Resistance, Bacterial; D005602:France; D005798:Genes, Bacterial; D006801:Humans; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D010957:Plasmids; D055815:Young Adult