Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants.
Pd(II)-catalyzed intramolecular amination of arenes is developed using either a one- or two-electron oxidant. The reaction protocol tolerates a wide range of deactivating groups including acetyl, cyano, and nitro groups. This catalytic reaction allows expedient syntheses of broadly useful substituted indolines or indoles.
Mei
Tian-Sheng
TS
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Wang
Xisheng
X
Yu
Jin-Quan
JQ
D000586:Amination; D002384:Catalysis; D004583:Electrons; D007211:Indoles / Q000138:chemical synthesis*; D016877:Oxidants / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D007211:Indoles; D016877:Oxidants; D010165:Palladium; C057812:indoline