[Fibrolamellar liver carcinoma: report of two cases and review of the literature].
Fibrolamellar hepatocellular carcinoma (FLC) is a rare histologic variant of hepatocellular carcinoma that appears most commonly in teenagers and young adults. The diagnosis is often made incidentally and surgical resection is the only curative treatment. Here we report two cases of incidental FLC involving a 19 year-old male, initially diagnosed with screening abdominal ultrasound, and a 14 year-old female that presented with abdominal pain. Diagnostic workup consisted of abdominal PET/CT and MR1 Imaging studies and tissue diagnosis was confirmed with percutaneous liver biopsy. Both patients were treated with radical liver resection/tumor excision. However, tumor recurrence was observed in both during short-term follow-up. The male patient was treated successfully with surgical treatment however the female patient succumbed top regression of disease.
Butte
Jean M
JM
Instituto Oncológico Fundación Arturo López Pérez, Santiago,Chile.
Waugh
Enrique
E
Meneses
Manuel
M
Pruzzo
Rossana
R
Carvallo
Cristian
C
Redondo
Francisca
F
Suárez
Claudio
C
Parada
Hugo
H
Amaral
Horacio
H
de La Fuente
Hernán
H
D000293:Adolescent; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000473:pathology / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009364:Neoplasm Recurrence, Local; D014057:Tomography, X-Ray Computed; D055815:Young Adult