[Studies on flavonoids and amides from herbs of Solanum lyratum].
OBJECTIVE
To investigate the chemical constituents in 95% alcohol extract of Solanum lyratum.


METHODS
The compounds were isolated by column chromatography over silica gel, and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated on the basis of physicochemical properties and spectral data.


RESULTS
Eleven compounds were isolated and identified as: formononetin (1), vanillic acid (2), genistein (3), apigenin (4), N-trans-feruloyltyramine (5), N-p-coumaroyltyramine (6), daidzein (7), caffeic aicd (8), protocatechuic acid (9), daidzin (10), and N-trans-feruloyl-3-methyldopamine (11).


CONCLUSIONS
For the first time, compound 11 was separated from Solanaceae plant, and compounds 5 and 10 were isolated from Solanum, and compounds 1, 3, 4, 7 and 9 were obtained from this plant for the first time.
Ren
Yan
Y
School of Pharmaceutical Science, Yantai University, Yantai 264005, China.
Shen
Li
L
Dai
Shengjun
S
D000438:Alcohols / Q000737:chemistry; D000577:Amides / Q000032:analysis* / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis* / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry; D032322:Solanum / Q000737:chemistry*
D000438:Alcohols; D000577:Amides; D005419:Flavonoids