title: 1H, 13C and 15N resonance assignments of the PDZ of microtubule-associated serine/threonine kinase 205 (MAST205) in complex with the C-terminal motif from the rabies virus glycoprotein.
abstract: Most of microbes hijack the cellular machinery to their advantage by interacting with specific target of the host cell. Glycoprotein of rabies virus is a key factor controlling the homeostasis of infected neuronal cells and proteins belonging to the human microtubule associated serine threonine kinase family have been identified as potential cellular partners. As a first step towards its structural study, we have assigned the backbone and side chain nuclei resonances of the PDZ domain (PSD-95, Discs Large, ZO-1) of MAST205 in complex with the C-terminal residues of the glycoprotein of rabies virus. The BMRB accession code is 155972.
authors.affiliation: Unité de Résonance Magnétique Nucléaire des Biomolécules, Département de Biologie Structurale et Chimie, CNRS URA 2185, Institut Pasteur, 28, rue du Docteur Roux, 75724, Paris Cedex 15, France.
authors.forename: Elouan
authors.initials: E
authors.lastname: Terrien
authors.forename: Catherine
authors.initials: C
authors.lastname: Simenel
authors.forename: Christophe
authors.initials: C
authors.lastname: Prehaud
authors.forename: Henri
authors.initials: H
authors.lastname: Buc
authors.forename: Muriel
authors.initials: M
authors.lastname: Delepierre
authors.forename: Monique
authors.initials: M
authors.lastname: Lafon
authors.forename: Nicolas
authors.initials: N
authors.lastname: Wolff
mesh_terms: D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D001665:Binding Sites; D002247:Carbon Isotopes / Q000737:chemistry; D006023:Glycoproteins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008869:Microtubule-Associated Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D046912:Multiprotein Complexes / Q000737:chemistry; D009587:Nitrogen Isotopes / Q000737:chemistry; D011485:Protein Binding; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry*; D017434:Protein Structure, Tertiary; D011522:Protons; D011820:Rabies virus / Q000737:chemistry*; D014764:Viral Proteins / Q000737:chemistry*
chemical_list: D002247:Carbon Isotopes; D006023:Glycoproteins; D008869:Microtubule-Associated Proteins; C084505:Mtssk protein, mouse; D046912:Multiprotein Complexes; D009587:Nitrogen Isotopes; D011522:Protons; D014764:Viral Proteins; D017346:Protein Serine-Threonine Kinases