The revolution of epigenetics in the field of autoimmunity.
Autoimmunity is believed to develop when genetically predisposed individuals encounter epigenetic modifications in response to environmental factors. Recent advances in the understanding of epigenetic mechanisms, their contribution to the immune function, and to the development of autoimmunity are presented in this special issue of Clinical Reviews in Allergy and Immunology. Potential new therapeutic strategies and biomarkers are also addressed.
Renaudineau
Yves
Y
EA2219 Immunology and Pathology, IFR148 ScinBios, Université de Brest, Brest, France. yves.renaudineau@univ-brest.fr
D000818:Animals; D001327:Autoimmune Diseases / Q000235:genetics* / Q000378:metabolism / Q000628:therapy*; D015551:Autoimmunity; D015415:Biomarkers / Q000378:metabolism; D044127:Epigenesis, Genetic; D006801:Humans
D015415:Biomarkers