Paraneoplastic extra limbic encephalitis associated with thymoma.
We report the case of a 55-year-old woman with thymoma diagnosed after finding of extra limbic encephalitis. She presented neurologic symptoms as seizure and aphasia; magnetic resonance imaging (MRI) of the brain showed multiple lesions located in insular, parietal and temporal lobes (in cortical and sub-cortical area). Brain biopsies confirmed the diagnosis of encephalitis and CT-scan of the thorax showed an anterior mediastinal mass suspected for thymoma. The patient was submitted to thymectomy through a median sternotomy and we assisted to secondary reduction of cerebral lesions and total remission of symptoms.
Rizzardi
Giovanna
G
Thoracic Surgery Unit, S. Croce Hospital, Cuneo, Italy. giovanna.rizzardi@libero.it
Campione
Andrea
A
Scanagatta
Paolo
P
Terzi
Alberto
A
D001706:Biopsy; D004660:Encephalitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020361:Paraneoplastic Syndromes, Nervous System / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D056346:Sternotomy; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013953:Thymus Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome