Reactivation of chronic hepatitis B infection related to imatinib mesylate therapy.
Imatinib (Gleevec, Novartis), an inhibitor of BCR-ABL, platelet-derived growth factor, and KIT receptor tyrosine kinases, is widely used in the treatment of chronic myelogenous leukemia and gastrointestinal stromal tumors. We describe a case of activation of chronic hepatitis B infection associated with imatinib therapy.
Lakhani
Shilen
S
Section of Gastroenterology and Hepatology, Washington Hospital Center, Georgetown University School of Medicine, 110 Irving Street NW, Washington, DC, 20010, USA.
Davidson
Lev
L
Priebat
Dennis A
DA
Sherker
Averell H
AH