Structure determination of chamaedryosides A-C, three novel nor-neo-clerodane glucosides from Teucrium chamaedrys, by NMR spectroscopy.
Three new nor-neo-clerodane diterpenes, named chamaedryoside A (1), B (2) and C (3), have been isolated from the organic extracts of Teucrium chamaedrys (L.) and their structural characterization has been accomplished by (1)H and (13)C-NMR spectra, and DEPT, by COSY, TOCSY, HSQC, HSQC-TOSCY and HMBC experiments, as well as by ESI-MS/MS techniques. The stereostructures have been elucidated by NOESY and computational calculations.
Fiorentino
Antonio
A
Dipartimento di Scienze della Vita, Laboratorio di Fitochimica, Seconda Università degli Studi di Napoli, Via Vivaldi 43, 81100 Caserta, Italy.
D'Abrosca
Brigida
B
Ricci
Andreina
A
Pacifico
Severina
S
Piccolella
Simona
S
Monaco
Pietro
P
D045785:Diterpenes, Clerodane / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry*; D031367:Teucrium / Q000737:chemistry*
D045785:Diterpenes, Clerodane; D005960:Glucosides; D010936:Plant Extracts; C040618:teucrium extract