title: Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate.
abstract: BACKGROUND
  Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months.
  
  
  METHODS
  From April 2003 to April 2008 36 patients affected by aneurysmal bone cysts were treated by selective arterial embolization with N-2-butyl cyanoacrylate. The study population comprised 20 male and 16 female patients with an age range of 3.3-60.8 years. Nine lesions were localized in the appendicular skeleton (1 in the upper and 8 in the lower limb), 4 in the thoracic cage (1 rib lesion and 3 scapular lesions), 17 in the pelvis and 6 in the spine (1 thoracic and 5 sacral localizations).
  
  
  RESULTS
  A total of 55 embolizations were performed: in 22 cases (61%) only one embolization was needed, whilst two embolizations were necessary in 9 cases (25%) and 3 in the remaining 5 patients (14%). The treatment was effective in 32 patients (94% ): follow-up was 0.9-5 years. In one patient, previously surgically treated, only the cyanoacrylate embolization turned out to be useful for healing the lesion. Another 7 patients underwent surgery during the study period. In the 55 procedures we performed we had 3 complications (5%): 2 cases of skin necrosis and 1 of transient paresis.
  
  
  CONCLUSIONS
  Arterial embolization with cyanoacrylate may be the treatment of choice for aneurysmal bone cysts. Embolization is a less invasive, lower cost, simpler procedure than surgery and is easily repeatable.
authors: Department of Interventional Angiographic Radiology, Rizzoli Orthopaedic Institute, Bologna, Italy.
authors: Giuseppe
authors: G
authors: Rossi
authors: Eugenio
authors: E
authors: Rimondi
authors: Tommaso
authors: T
authors: Bartalena
authors: Antonio
authors: A
authors: Gerardi
authors: Marco
authors: M
authors: Alberghini
authors: Eric Lodwijk
authors: EL
authors: Staals
authors: Costantino
authors: C
authors: Errani
authors: Giuseppe
authors: G
authors: Bianchi
authors: Angelo
authors: A
authors: Toscano
authors: Mario
authors: M
authors: Mercuri
authors: Daniel
authors: D
authors: Vanel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017824:Bone Cysts, Aneurysmal / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D004621:Embolization, Therapeutic / Q000379:methods*; D004659:Enbucrilate / Q000008:administration & dosage*; D005260:Female; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006490:Hemostatics; D004659:Enbucrilate