title: Antifungal activity of bioactive triterpenoid saponin from the seeds of Cassia angustifolia.
abstract: A novel oleanen type triterpenoid glycoside has been isolated from butanolic seed extracts of Cassia angustifolia. Its structure was elucidated as 3-O-{beta-D-glucuronopyranosyl-(1 --> 4)-[beta-D-galactopyranosyl-(1 --> 2)]-beta-D-xylopyranosyl-(1 --> 3)-beta-D-glucopyranosyl}-2, 16alpha-dihydroxy-4, 20-hydroxy methyl olean-12-ene-28-oic acid on the basis of spectral evidence (i.e. FTIR, (1)H NMR, (13)C NMR and FAB-MS data). The isolated saponin was tested for its antifungal activity, where the maximum inhibition was found in Colletotrichium dematium.
authors: Department of Postgraduate and Research in Chemistry, Rani Durgawati University, Jabalpur, India. noor_afshan25@yahoo.com
authors: Noor Afshan
authors: NA
authors: Khan
authors: Ashutosh
authors: A
authors: Srivastava
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry*; D029846:Senna Plant / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes