Isolation of a new metabolite from biotransformation of daidzein by Aspergillus oryzae.
Two compounds were isolated from biotransformation of daidzein, a soybean isoflavone, by Aspergillus oryzae. One was 6,7,8,4'-tetrahydroxyisoflavone, an A-ring dihydroxylated daidzein, and the other was a novel compound which had the cleaved B-ring of daidzein. The former was perhaps derived from 8-hydroxydaidzein and/or 6-hydroxydaidzein, and had high DPPH radical-scavenging activity.
Chen
Yu-Chi
YC
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka, Japan. askachen@mail.vnu.edu.tw
Sugiyama
Yasumasa
Y
Hirota
Akira
A
D001236:Aspergillus oryzae / Q000737:chemistry* / Q000378:metabolism*; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates / Q000737:chemistry
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007529:Isoflavones; D010851:Picrates; C004742:daidzein; C004931:1,1-diphenyl-2-picrylhydrazyl