Nickel/AlMe(2)Cl-catalysed carbocyanation of alkynes using arylacetonitriles.
Nickel/Lewis acid dual catalysis was found to effect the carbocyanation reaction of alkynes using arylacetonitriles, giving a range of triply substituted acrylonitriles; the reaction of optically active alpha-phenylpropionitrile suggested a reaction mechanism that involves oxidative addition of a C-CN bond with retention of its absolute configuration.
Yada
Akira
A
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan.
Yukawa
Tomoya
T
Nakao
Yoshiaki
Y
Hiyama
Tamejiro
T