A case of POEMS syndrome with mixed hyaline vascular and plasma cell type Castleman's disease.
We report a 43-year-old man who developed progressive ascending sensorimotor polyneuropathy, a solitary bone plasmacytoma originating from a rib and an axillary lymph node with features of Castleman's disease, mixed hyaline vascular and plasma cell type. He was diagnosed of having non-Hodgkin's lymphoma seven years back and was treated. Examination revealed a smooth goitre, thickened skin, white nails, small testes and ankle oedema. Investigations revealed a monoclonal para-proteinaemia of 7.83 g/l and elevated levels of serum TSH and prolactin. In this case the Castleman's disease is localised and the lymphoma preceded the Castleman's disease.
Ruwan
K P
KP
Parakramawansha
C
C
Wijeweera
I
I
Ratnatunga
Neelakanthi
N
Sumanasekara
W G V
WG
D000328:Adult; D005871:Castleman Disease / Q000175:diagnosis* / Q000532:radiotherapy; D006801:Humans; D008297:Male; D016878:POEMS Syndrome / Q000175:diagnosis* / Q000532:radiotherapy