Exogenous heat shock proteins (HSP70) significantly inhibit endotoxin-induced activation of human neutrophils.
Yurinskaya
M M
MM
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
Vinokurov
M G
MG
Zatsepina
O G
OG
Garbuz
D G
DG
Guzhova
I V
IV
Rozhkova
E A
EA
Suslikov
A V
AV
Karpov
V L
VL
Evgen'ev
M B
MB
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D039481:CD11b Antigen / Q000378:metabolism; D002162:Camelus; D004927:Escherichia coli Infections / Q000276:immunology / Q000517:prevention & control; D018840:HSP70 Heat-Shock Proteins / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008070:Lipopolysaccharides / Q000633:toxicity*; D018375:Neutrophil Activation / Q000187:drug effects* / Q000276:immunology; D009504:Neutrophils / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D017382:Reactive Oxygen Species / Q000378:metabolism; D011994:Recombinant Proteins / Q000494:pharmacology; D018805:Sepsis / Q000276:immunology / Q000517:prevention & control
D039481:CD11b Antigen; D018840:HSP70 Heat-Shock Proteins; C509295:ITGAM protein, human; D008070:Lipopolysaccharides; D017382:Reactive Oxygen Species; D011994:Recombinant Proteins; C440499:lipopolysaccharide, Escherichia coli O111 B4