title: Genetic analysis of 15 STR loci in the population of Zhejiang Province (Southeast China).
abstract: Fifteen autosomal STR loci were analyzed from a population sample of 598 unrelated individuals residing in Zhejiang Province. We report allele frequencies distribution and statistical parameters for all 15 STR loci, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818 and FGA. Allele frequencies, the observed heterozygosity (Ho), the polymorphic information content (PIC), and the probability of paternity exclusion (PE) were calculated. All loci were in accordance with Hardy-Weinberg equilibrium (P>0.05). Our studied population data were compared with the previously published population data of other ethnic groups or areas in China. Our results of present study were valuable for human identification and paternity tests in Zhejiang Province.
authors: Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang, China.
authors: Yuning
authors: Y
authors: Zhu
authors: Shiming
authors: S
authors: Lu
authors: Zhenwei
authors: Z
authors: Xie
authors: Yan
authors: Y
authors: Chen
authors: Jianfei
authors: J
authors: You
mesh_terms: D000483:Alleles; D002681:China / Q000208:ethnology; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D016172:DNA Fingerprinting / Q000379:methods; D005006:Ethnicity / Q000235:genetics*; D005554:Forensic Medicine / Q000379:methods; D005787:Gene Frequency; D005828:Genetics, Population; D005843:Geography; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D021141:Nucleic Acid Amplification Techniques; D010334:Paternity; D011110:Polymorphism, Genetic; D011786:Quality Control; D012015:Reference Standards
chemical_list: D004247:DNA