An efficient modular approach for the assembly of s-linked glycopeptoids.
A short and convenient methodology for the synthesis of S-glycosylated peptoid models is described. The thioglycosylated building blocks were prepared from proper peracetylated sugars via glycosyl iodides in a one-pot fashion and directly employed in a submonomer solid-phase stategy.
Comegna
Daniela
D
Dipartimento di Chimica, Università di Salerno, Via Ponte don Melillo, 84084 Fisciano (SA), Italy. dcomegna@unisa.it
De Riccardis
Francesco
F
D020650:Combinatorial Chemistry Techniques; D006017:Glycolipids / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D006847:Hydrocarbons, Iodinated / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D034444:Peptoids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D006017:Glycolipids; D006847:Hydrocarbons, Iodinated; D034444:Peptoids