[Pneumocystosis distribution among accident liquidators in the Chernobyl nuclear power plant in remote period].
The goal of the present study was to discover etiological role of Pneumocystis carini/jiroveci and to determine frequency of pneumocystic infection in the structure of bronchopulmonary pathology among armenians-liquidators of accident consequences in the Chernobyl Nuclear Power Plant. For the study, 65 patients-liquidators with diagnosed pneumonia, 44 liquidators with chronic bronchitis and 34 with bronchial asthma were examined. The control group was included 65 patients with pneumonia, 44 with chronic bronchitis, 34 with bronchial asthma which were unlinked with radionucleotide aggression. Mean age in main group was 46,9 and in control group- 47,6 years old. Main and control groups were randomized by sexual characteristics also. Serologic examinations were performed by the ELISA (enzyme-linked immunoSorbent assay) and method of immunofluorescent detection of P.carinii. Circulation of pneumocystosis etiologic agent among patients-liquidators of accident consequences in the Chernobyl Nuclear Power Plant with different bronchopulmonary pathology was established and high percentage of seropositivity was revealed. Overall these data revealed high probability of Pneumocystis carini/jiroveci in the etiology of bronchopulmonary pathology among liquidators of accident consequences in the the Chernobyl Nuclear Power Plant. Even among immunocompromised patients, liquidators of accident consequences, represent an exclusive group, that is in risk for activation of latent infection or new infection with P. carini/jiroveci. Therefore these findings suggest that there is a need for regular complex epidemiological monitoring of these patients.
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D047852:Chernobyl Nuclear Accident; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D055848:Nuclear Power Plants; D016273:Occupational Exposure; D011020:Pneumonia, Pneumocystis / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D011832:Radiation Injuries / Q000150:complications*; D016036:Seroepidemiologic Studies
D007074:Immunoglobulin G; D007075:Immunoglobulin M