Amphetamine recapitulates developmental programs in the zebrafish.
Addictive drugs hijack the human brain's 'reward' systems. A zebrafish model of addiction has recently been used to query changes in gene expression during this process.
Cadet
Jean Lud
JL
Molecular Neuropsychiatry Branch, National Institute on Drug Abuse/IRP, NIH Biomedical Research Center, 251 Bayview Blvd, Baltimore, MD 21224, USA. jcadet@intra.nida.nih.gov
D000661:Amphetamine / Q000633:toxicity*; D000818:Animals; D016739:Behavior, Addictive / Q000235:genetics; D000697:Central Nervous System Stimulants / Q000633:toxicity; D003214:Conditioning, Classical / Q000187:drug effects; D008954:Models, Biological; D012201:Reward; D015398:Signal Transduction / Q000187:drug effects; D014158:Transcription, Genetic / Q000187:drug effects / Q000235:genetics*; D015027:Zebrafish / Q000235:genetics* / Q000502:physiology
D000697:Central Nervous System Stimulants; D000661:Amphetamine