The effect of ovarian cyst aspiration on IVF treatment with GnRH.
OBJECTIVE
The formation of cysts during IVF treatment may negatively influence the outcome. The aim of this study is to compare conservative management versus aspiration for functional ovarian cysts before ovarian stimulation for ART.


METHODS
Women who underwent IVF cycle with a long protocol, and developed ovarian cysts, they were randomly divided into a cyst aspiration group (n = 90) in which the cysts were aspirated after diagnosis and a no-intervention group (n = 90) for which the conservative treatment was continued following cyst diagnosis.


RESULTS
The FSH level in women with ovarian cysts in the aspiration group was significantly higher than that in the no-intervention group (9.1 +/- 4.5 vs. 6.5 +/- 1.78 mIU/ml, p = 0.001). HMG requirement in that aspiration group was significantly higher than that in the non- intervention group (26.2 +/- 9.7 vs. 21.85 +/- 7.7, p = 0.0001). The embryo score in the no-intervention group was higher than the aspiration group (18 vs. 16, p = 0.0001).The cycle cancellation rate was significantly higher in the aspiration group than the no-intervention group. The pregnancy rate was higher but not significantly in the aspiration group than no-intervention group.


CONCLUSIONS
Cyst aspiration did not promote retrieved oocyte in quality and in number. Because cyst aspiration requires anesthesia and is expensive, conservative management is better and without improving the IVF outcome.
Firouzabadi
Razieh Dehghani
RD
Research and Clinical Center for Infertility, Shahid Sedughi University of Medical Sciences and Health Services, Yazd, Iran. dr_firouzabadi@ssu.ac.ir
Sekhavat
Leila
L
Javedani
Maryam
M
D000328:Adult; D044963:Biopsy, Fine-Needle; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D008875:Middle Aged; D054315:Oocyte Retrieval; D010048:Ovarian Cysts / Q000139:chemically induced* / Q000601:surgery*; D010062:Ovulation Induction / Q000009:adverse effects; D055815:Young Adult
D007987:Gonadotropin-Releasing Hormone