Serum ALT: LDH ratio in typhoid fever and acute viral hepatitis.
In 100 consecutive children aged below 18 years with confirmed typhoid fever, 29 had moderate hepatitis. Serum alanine amino transferase: lactate dehydrogenase (ALT: LDH) ratios of these 29 children at the time of hospitalization were compared with that of 29 children with acute viral hepatitis. The serum ALT: LDH ratio levels (expressed in multiples of upper limit of normal) was found to be less than 9 in typhoid hepatitis and more than 9 in acute viral hepatitis. Serum ALT: LDH ratio helps to differentiate typhoid hepatitis from acute viral hepatitis.
Balasubramanian
S
S
Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, 12A, Nageswara Road, Nungambakkam, Chennai 600 034, TN, India. sbsped53@sify.com
Kaarthigeyan
K
K
Srinivas
S
S
Rajeswari
R
R
D000410:Alanine Transaminase / Q000097:blood*; D002675:Child, Preschool; D005260:Female; D006525:Hepatitis, Viral, Human / Q000201:enzymology*; D006801:Humans; D007223:Infant; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D014435:Typhoid Fever / Q000201:enzymology*
D007770:L-Lactate Dehydrogenase; D000410:Alanine Transaminase