title: Survival and complications of computer aided-designing and computer-aided manufacturing vs. conventionally fabricated implant-supported reconstructions: a systematic review.
abstract: OBJECTIVE
  The aim of this systematic review was to assess the internationally published survival and complication rates of implant-supported computer-aided designing (CAD) and computer-aided manufacturing (CAM)-fabricated restorations and to compare them with those of conventionally fabricated implant-supported restorations.
  
  
  METHODS
  An electronic MEDLINE search was conducted to identify prospective and retrospective cohort studies on CAD-CAM fabricated implant-supported restorations with a mean follow-up time of at least 1 year. Failure and complication rates were evaluated and descriptive statistics were performed.
  
  
  RESULTS
  An electronic MEDLINE search revealed four studies reporting on implant-supported CAD-CAM fabricated restorations. The cumulative 5-year survival rate of implants supporting full-arch-fixed dental prostheses (FDPs) ranged from 81.4% to 95.6%. Reported survival rates of implants supporting all-ceramic single crowns (SCs) were 100% [95% confidence interval (CI): 92.4-100]. The cumulative 5-year survival rate for full-arch FDPs ranged from 72.2% to 100%. Reported cumulative 5-year survival rates for all-ceramic SCs were 100% (95% CI: 92.4-100%). Technical complications were reported in two of the four selected studies and the estimated annual failure rate for chipping/fracture of the veneering material was 0.43 (95% CI: 0.06-3.06) for implant-supported all-ceramic SCs and 3.61 (95% CI: 2.05-6.36) for implant-supported FDPs.
  
  
  CONCLUSIONS
  Only a small number of clinical studies reporting on implant-supported CAD-CAM fabricated restorations exists which makes a scientifically valid comparison with conventionally fabricated restorations impossible.
authors: Department of Prosthodontics, Propaedeutics and Dental Materials, School of Dentistry Christian-Albrechts University at Kiel, Kiel, Germany.
authors: Sönke
authors: S
authors: Harder
authors: Matthias
authors: M
authors: Kern
mesh_terms: D017076:Computer-Aided Design; D015921:Dental Implants; D017267:Dental Prosthesis Design / Q000009:adverse effects / Q000379:methods; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D006801:Humans
chemical_list: D015921:Dental Implants