Genetic and genomic insights into age at natural menopause.
The age at natural menopause shows great variability. It has been proposed that early age at menopause is a risk factor for osteoporosis and cardiovascular disease, whereas later age at menopause is a risk factor for breast cancer. In addition, it is thought that the genetic factors accounting for the genetic variability in age at menopause could also play a role in those diseases, as well as infertility in women. In this minireview we comment on the latest genetics and genomics insights into age at natural menopause.
Moron
Francisco Jesus
FJ
Department of Structural Genomics, Neocodex SL, Avda, Charles Darwin 6, Acceso A, Isla de la Cartuja, 41092, Sevilla, Spain.
Ruiz
Agustin
A
Galan
Jose Jorge
JJ