High seroprevalence of caseous lymphadenitis in Brazilian goat herds revealed by Corynebacterium pseudotuberculosis secreted proteins-based ELISA.
We conducted a seroepidemiological survey to determine the prevalence of caseous lymphadenitis (CLA) in goat herds in Minas Gerais state, Brazil. Serum samples were collected from goats (n=676) from 108 rural properties in 2001, covering most of the sub-regions of this ca. 586,500 square kilometer state. Antibodies against Corynebacterium pseudotuberculosis secreted proteins were detected by an indirect enzyme-linked immunosorbent assay (ELISA). Most of the animals (78.9%) tested positive for CLA; 98% of flocks presented at least one seropositive animal. Goats managed under an extensive production system had a significantly higher seroprevalence of CLA than those in intensive and semi-intensive operations. The age distribution of the animals in the flocks affected the prevalence of this disease; however, goat breed did not. We found seropositivity against C. pseudotuberculosis to be highly prevalent in these Brazilian goat herds; consequently, appropriate management practices for the control of CLA should be implemented.
Seyffert
N
N
Laboratório de Genética Celular e Molecular, Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, CP 486, CEP 31270-901, Belo Horizonte, MG, Brazil.
Guimarães
A S
AS
Pacheco
L G C
LG
Portela
R W
RW
Bastos
B L
BL
Dorella
F A
FA
Heinemann
M B
MB
Lage
A P
AP
Gouveia
A M G
AM
Meyer
R
R
Miyoshi
A
A
Azevedo
V
V
D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology; D001938:Brazil / Q000453:epidemiology; D003354:Corynebacterium Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D016925:Corynebacterium pseudotuberculosis; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D006041:Goats / Q000382:microbiology; D008199:Lymphadenitis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D016036:Seroepidemiologic Studies
D001426:Bacterial Proteins