Multiple sclerosis: human model for EAE?
Concepts of the pathogenesis of MS are based on evidence from the animal model, EAE. Yet, the relationship between human MS and EAE is far from being a one-way road: many paths lead from the bedside back to animals in the laboratory.
Hohlfeld
Reinhard
R
Institute of Clinical Neuroimmunology, Ludwig Maximilians University of Munich, Campus Grosshadern, Germany. reinhard.hohlfeld@med.unimuenchen.de
D000818:Animals; D004195:Disease Models, Animal; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology* / Q000473:pathology; D006801:Humans; D008285:Major Histocompatibility Complex / Q000276:immunology; D018448:Models, Immunological; D009103:Multiple Sclerosis / Q000276:immunology* / Q000473:pathology / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology