title: Necrobiotic xanthogranuloma without paraproteinaemia: marked improvement with psoralen ultraviolet A treatment.
abstract: Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinaemia and in some cases multiple myeloma. Treatment is therefore aimed at the underlying associated haematological abnormality. However, isolated NXG cases have been reported. We report a case of isolated NXG that responded very well to systemic psoralen ultraviolet A (PUVA) treatment. The rationale for this treatment was the successful use of PUVA treatment in other necrobiotic conditions such as granuloma annulare and necrobiosis lipoidica.
authors: Department of Dermatology, Cumberland Infirmary, Carlisle, UK. firas55@hotmail.com
authors: F A
authors: FA
authors: Al-Niaimi
authors: G
authors: G
authors: Dawn
authors: N H
authors: NH
authors: Cox
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D017441:Necrobiotic Disorders / Q000188:drug therapy* / Q000473:pathology; D011701:PUVA Therapy / Q000379:methods*; D016896:Treatment Outcome; D014973:Xanthomatosis / Q000188:drug therapy* / Q000473:pathology