Body and major organ weights of A/J-Chr 11(SM) consomic mice.
The body and major organ weights of A/J-Chr 11(SM) consomic mice were compared to those of the progenitor strains, A/J and SM/J. The weights of the body and organs, except for those of the brain and uterus, were significantly greater in A/J mice than in SM/J mice. However, those of consomic mice were highly variable. For example, the average body weight of consomic mice was significantly greater than that of SM/J mice and nearly equal to that of A/J mice. Chromosome 11 of SM/J mice induced various significant changes of the organ weights of A/J mice, especially those of the brain, lung, kidney, adrenal, and ovary, demonstrating the importance of this chromosome in determining the phenotypes.
Tanaka
Shin
S
Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology, Gengo, Morioko-cho, Obu, Japan.
Mizorogi
Toshihiro
T
Nishijima
Kazutoshi
K
Kuwahara
Sachi
S
Tsujio
Masashi
M
Aoyama
Hiroaki
H
Taguchi
Chie
C
Kobayashi
Misato
M
Horio
Fumihiko
F
Ohno
Tamio
T
D000818:Animals; D001835:Body Weight / Q000235:genetics*; D033481:Chromosomes, Mammalian; D005260:Female; D051379:Mice; D020297:Mice, Congenic / Q000235:genetics* / Q000254:growth & development; D008805:Mice, Inbred A / Q000235:genetics* / Q000254:growth & development; D009929:Organ Size / Q000235:genetics*; D010641:Phenotype