title: Massive hemorrhage in hemangioblastomas   Literature review.
abstract: Massive hemorrhage is a very uncommon event among hemangioblastomas. Forty-four cases have been reported before this review. Thorough analysis of all reported cases on literature was accomplished. The majority presented as parenchymatous or subarachnoid bleedings. Subarachnoid hemorrhage was only associated with spinal hemangioblastomas, while parenchymatous bleedings were more, but not only, originated from cranial instances. Ventricular hemorrhage from a hemangioblastoma was exceptional, with only two previous cases bleeding directly into the ventricular compartment. To our knowledge, the illustrative case is the first one of pure tetraventricular hemorrhage from a hemangioblastoma. When hemangioblastoma bleeding occurs, it is usually the very first clinical presentation of a previously undetected tumor. Solid type, large size, and spinal-radicular locations are more frequently related to hemorrhage. Hemorrhage following hemangioblastoma embolization and the association of this tumor with other bleeding lesions, such as arteriovenous malformations and aneurysms, is also discussed.
authors: Regional Service of Neurosurgery, Virgen de la Arrixaca University Hospital, 30120 El Palmar, Murcia, Spain. javierrosdesanpedro@yahoo.es
authors: Javier Ros
authors: JR
authors: de San Pedro
authors: Fernando Alarcón
authors: FA
authors: Rodríguez
authors: Belén Ferri
authors: BF
authors: Níguez
authors: Juan F Martínez-Lage
authors: JF
authors: Sánchez
authors: Antonio López
authors: AL
authors: López-Guerrero
authors: Matías Felipe
authors: MF
authors: Murcia
authors: Antonio M Ruíz-Espejo
authors: AM
authors: Vilar
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D018450:Disease Progression; D004621:Embolization, Therapeutic / Q000009:adverse effects; D005260:Female; D018325:Hemangioblastoma / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000453:epidemiology; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000209:etiology; D014057:Tomography, X-Ray Computed