[Studies on chemical constituents of Ligularia altaica].
OBJECTIVE
To study the chemical constituents of Lighularia altaica.


METHODS
Various chromatographic techniques were used to isolate and purify the chemical compounds, their structure were elucidated by means of mass, physico-chemical properties and NMR spectral data.


RESULTS
Nine compounds were obtained as: lupeol (1), oleanolic acid (2), 3beta, 16beta-dihydroxy-12-oleanen-28-al (3), ergosterol peroxide (4), stigmasta-7-en-ol (5), 11-hydroxy-10,11-dihydro-euparin (6), 5-hydroxybenzofuran-2(3H) -one- (7), except for beta-sitosterol (8) and daucostrol (9).


CONCLUSIONS
Compounds 3 - 7 are isolated for the first time from this genus, the other compounds are obtained from this plant for the first time.
Zhang
Chao-Feng
CF
Key Laboratory of Modern Chinese Medicines of Ministry of Education/Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. inchaofeng@126.com
Wang
Qiong
Q
Zhang
Mian
M
D019659:Asteraceae / Q000737:chemistry*; D004875:Ergosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification*; D012997:Solvents / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D000094042:Lupanes
D004875:Ergosterol; D009828:Oleanolic Acid; D053978:Pentacyclic Triterpenes; D012855:Sitosterols; D012997:Solvents; C528302:3beta,16beta-dihydroxy-12-oleanen-28-al; C025473:gamma-sitosterol; C010480:lupeol; D000094042:Lupanes; C036071:ergosterol-5,8-peroxide