[Adaptation and validation of the Spanish version of a disease-specific quality of life measure in patients with systemic lupus erythematosus: the Lupus quality of life].
OBJECTIVE
Systemic Lupus Erythematosus (SLE) is an auto-immune disease that seriously affects quality of life. There are various specific instruments that measure health-related quality of life (HRQOL), but none of them has been adapted to Spanish. We intended to adapt and validate in a Spanish population a specific HRQOL measure in patients with SLE.


METHODS
The adaptation was carried out using the translation and back-translation method of the English version of the LupusQoL, with its subsequent application to 115 adults with SLE.


RESULTS
The factorial analysis identified 5 domains of the LupusQoL; the reliability tests showed a high Cronbach alpha coefficient of 0.977 and a high Guttman two-halves coefficient of 0.936; the significant correlations of the LupusQoL with the SF-36 showed a high convergent validity of the questionnaire; in addition, the correlations with the SLEDAI and SLICC were low, which showed its discriminated validity.


CONCLUSIONS
The Spanish version of the LupusQoL has stable psychometric properties to measure HRQOL in people with SLE in clinical and research settings in a Spanish-speaking population.
González-Rodríguez
Viviana
V
Departamento de Personalidad, Evaluación y Tratamiento Psicológico, Facultad de Psicología, Universidad de Granada, España.
Peralta-Ramírez
María Isabel
MI
Navarrete-Navarrete
Nuria
N
Callejas-Rubio
Jose Luis
JL
Santos Ruiz
Ana María
AM
Khamashta
Munther
M
D000328:Adult; D005260:Female; D006801:Humans; D007802:Language; D008180:Lupus Erythematosus, Systemic; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires