title: Semiquantitative analysis of surgical biopsies of distinct lung lobes of patients with usual interstitial pneumonia/idiopathic pulmonary fibrosis.
abstract: OBJECTIVE
  To evaluate the differences between surgical biopsies of distinct lung lobes in terms of the histopathological features of usual interstitial pneumonia, using a semiquantitative score.
  
  
  METHODS
  We selected all of the patients diagnosed with idiopathic pulmonary fibrosis and submitted to surgical biopsy in two distinct lobes between 1995 and 2005 at the Hospital São Paulo and other hospitals operated by the Federal University of São Paulo. In the histological evaluation of the specimens, we used a semiquantitative method based on previous studies, assigning a score to each of the biopsied sites.
  
  
  RESULTS
  In this sample of patients, we found no statistically significant differences that would alter the stage of the disease, based on the score used. This finding was independent of the biopsy site (middle lobe or lingular segment).
  
  
  CONCLUSIONS
  No significant histological differences were found between the lung lobes studied. The definitive histological diagnosis of usual interstitial pneumonia did not alter the stage of the disease.
authors: Universidade para o Desenvolvimento do Estado e da Região do Pantanal, Campo Grande, MS, Brasil. jjsgon@gmail.com
authors: José Júlio Saraiva
authors: JJ
authors: Gonçalves
authors: Luiz Eduardo Villaça
authors: LE
authors: Leão
authors: Rimarcs Gomes
authors: RG
authors: Ferreira
authors: Renato
authors: R
authors: Oliveira
authors: Luiz Hirotoshi
authors: LH
authors: Ota
authors: Ricardo Sales
authors: RS
authors: dos Santos
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D005260:Female; D006801:Humans; D054988:Idiopathic Interstitial Pneumonias / Q000473:pathology*; D054990:Idiopathic Pulmonary Fibrosis / Q000473:pathology; D008168:Lung / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D020775:Thoracic Surgery, Video-Assisted