Medical genetics:   Sporadic dystrophic epidermolysis bullosa with albopapuloid  and prurigo- and folliculitis-like lesions.
A case of sporadic dystrophic epidermolysis bullosa (DEB) with albopapuloid and prurigo- and folliculitis-like lesions is reported. Histopathology of the scalp biopsy showed hyperkeratosis, a subepidermal cleft near the orifice of a hair follicle, dermal fibrosis, and a moderate perivascular and perifollicular lymphohistiocytic inflammatory cell infiltrate in the papillary dermis, without neutrophilic infiltrate in the orifice of the hair follicle. It is uncertain whether the present case should be classified as DEB pruriginosa or represents a new subtype of DEB.
Fan
Yi-Ming
YM
Department of Dermatology, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China. ymfan1963@163.com
Yang
Yan-Ping
YP
Li
Shun-Fan
SF
D000293:Adolescent; D001706:Biopsy; D024143:Collagen Type VII / Q000235:genetics; D020405:Dermis / Q000473:pathology*; D016108:Epidermolysis Bullosa Dystrophica / Q000235:genetics* / Q000473:pathology*; D005355:Fibrosis; D005499:Folliculitis / Q000235:genetics* / Q000473:pathology*; D018859:Hair Follicle / Q000473:pathology; D006801:Humans; D008297:Male
D024143:Collagen Type VII