Management of pediatric tumor lysis syndrome in the emergency department.
Tumor lysis syndrome is most often seen after the treatment of blood and solid malignancies. The resultant hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia can lead to life threatening complications. Expeditious evaluation and therapy are paramount in preventing the most serious sequelae of acute renal failure and fatal dysrhythmias.
Zonfrillo
Mark R
MR
Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. zonfrillo@email.chop.edu
D002648:Child; D004636:Emergency Service, Hospital; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology / Q000628:therapy; D054559:Hyperphosphatemia / Q000209:etiology / Q000628:therapy; D033461:Hyperuricemia / Q000209:etiology / Q000628:therapy; D006996:Hypocalcemia / Q000209:etiology / Q000628:therapy; D017582:Renal Replacement Therapy; D015275:Tumor Lysis Syndrome / Q000150:complications / Q000453:epidemiology / Q000628:therapy*