Granulocyte colony-stimulating factor in patients with ST segment elevation myocardial infarction: a disappointment-stimulating factor?
Cellular cardiomyoplasty is an investigational technique that may have the potential to reduce myocardial infarct size and improve cardiac function in patients with ischemic heart disease. However, experience with this approach is still limited to a few small trials, some which were not blinded or had other design problems. Although there is no sufficient evidence to believe that granulocyte colony-stimulating factor (G-CSF) may be a useful treatment in patients with ST segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention, further large-scale clinical studies are needed to examine the exact role of G-CSF in the management of those patients.
Celik
Turgay
T
Iyisoy
Atila
A
Kardesoglu
Ejder
E
Celik
Murat
M
D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000601:surgery; D016032:Randomized Controlled Trials as Topic / Q000379:methods
D016179:Granulocyte Colony-Stimulating Factor