title: Prevalence of uveitic secondary glaucoma and success of nonsurgical treatment in adults and children in a tertiary referral center.
abstract: OBJECTIVE
  The aim of this study is to compare treatment strategies, the success of topical and systemic therapy, and the need for glaucoma surgery in children and adults with secondary uveitic glaucoma.
  
  
  METHODS
  Retrospective observational case series with 1997 consecutive new uveitis patients.
  
  
  RESULTS
  Overall, 176 patients (8.8%) suffered from secondary glaucoma (n = 126) or ocular hypertension (n = 50). All patients received topical therapy, and 107 (62%) patients also received systemic glaucoma therapy. Topical therapy was successful (IOP <or= 21 mmHg) in 24% of adults and 26% of children. Surgery was required in 59% of children and in 35% of adults (p =.02). The number of surgical interventions differed per patient with 2.6 procedures in children compared to 1.6 procedures in adults (p <.001).
  
  
  CONCLUSIONS
  Only a limited number of patients with secondary uveitic glaucoma can be sufficiently controlled with topical and systemic antiglaucomatous therapy alone. There is a significantly higher need for glaucoma operations in children.
authors: Department of Ophthalmology, St. Franziskus-Hospital Muenster, Muenster, Germany. carsten.heinz@uveitiszentrum.de
authors: Carsten
authors: C
authors: Heinz
authors: Jorg M
authors: JM
authors: Koch
authors: Beatrix
authors: B
authors: Zurek-Imhoff
authors: Arnd
authors: A
authors: Heiligenhaus
mesh_terms: D000287:Administration, Topical; D000328:Adult; D002257:Carbonic Anhydrase Inhibitors / Q000008:administration & dosage; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D013508:Ophthalmologic Surgical Procedures / Q000706:statistics & numerical data; D015995:Prevalence; D012017:Referral and Consultation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications*
chemical_list: D002257:Carbonic Anhydrase Inhibitors