title: Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy.
abstract: A 23-year-old woman developed ischemic stroke (IS) 8 to 12 hours after ingestion of sumatriptan (ST) and then developed mucosal bleeding secondary to acute thrombocytopenia likely due to dipyridamole (DP) on the 10th day poststroke. Sumatriptan-associated IS and DP-induced thrombocytopenia are rare events in themselves and their sequential occurrence in the same patient is quite exceptional. We compare our case to other similar cases in the literature.
authors: Care of the Elderly, Royal Preston Hospital, Preston, United Kingdom.
authors: Carolyn
authors: C
authors: Adams
authors: Allen
authors: A
authors: Dhirendra
authors: Paul R J
authors: PR
authors: Ames
mesh_terms: D000208:Acute Disease; D000328:Adult; D002545:Brain Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D004176:Dipyridamole / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D007049:Iatrogenic Disease; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D058825:Serotonin 5-HT1 Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D020521:Stroke / Q000139:chemically induced* / Q000188:drug therapy; D018170:Sumatriptan / Q000008:administration & dosage / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D010975:Platelet Aggregation Inhibitors; D058825:Serotonin 5-HT1 Receptor Agonists; D004176:Dipyridamole; D018170:Sumatriptan