Exploration of polymethacrylate structure-property correlations: Advances towards combinatorial and high-throughput methods for biomaterials discovery.
In this review, we discuss the synthesis, characterization, physical properties, and applications of polymethacrylates and describe physical and biological structure-property correlations relevant to many high performance applications. We also track the advancement of material-property space from the 'traditional' mode of materials design to the emerging, state-of-the-art combinatorial and in silico methods. Particularly, this article places emphasis on recent advances in the automated combinatorial synthesis and development of high-throughput characterization methods. As a future perspective, we believe that the realization of combinatorial, high-throughput, and computational methods will allow for the rapid exploration of a vast polymethacrylate library property space.
Holmes
Paul F
PF
Department of Chemistry and Chemical Biology and The New Jersey Center for Biomaterials, 145 Bevier Road, Rutgers-The State University of New Jersey, Piscataway, NJ 08854.
Bohrer
Mike
M
Kohn
Joachim
J