Osteoimmunology: Wnt antagonists: for better or worse?
Molecules involved in developmental signaling pathways have emerged as therapeutic targets for various rheumatic diseases. New research sheds light on the consequences of interfering with these processes.
Lories
Rik J
RJ
Laboratory for Skeletal Development and Joint Disorders, Division of Rheumatology, Katholieke Universiteit Leuven, Leuven, Belgium.
Luyten
Frank P
FP
D000818:Animals; D018501:Antirheumatic Agents / Q000009:adverse effects*; D006801:Humans; D051379:Mice; D015398:Signal Transduction / Q000187:drug effects*; D025242:Spondylarthropathies / Q000188:drug therapy*; D051153:Wnt Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism
D018501:Antirheumatic Agents; D051153:Wnt Proteins