Pandemic influenza A(H1N1)v viruses currently circulating in New Zealand are sensitive to oseltamivir.
New Zealand, like other southern hemisphere countries with a temperate climate, has been in the winter period with seasonal influenza activity. New Zealand has also experienced a dramatic increase in the number of cases of pandemic influenza A(H1N1)v virus. Early reports from the northern hemisphere at the beginning of the pandemic showed that the virus was sensitive to the antiviral drug oseltamivir. In this study we report that pandemic influenza A(H1N1)v viruses currently circulating in New Zealand are sensitive to oseltamivir, but seasonal influenza A(H1N1) viruses - the co-circulating predominant seasonal strain, is resistant to oseltamivir.
Hall
R J
RJ
World Health Organization (WHO) National Influenza Centre, Institute of Environmental Science and Research (ESR) Ltd., National Centre for Biosecurity and Infectious Disease, Upper Hutt, New Zealand. richard.hall@esr.cri.nz
Peacey
M P
MP
Ralston
J C
JC
Bocacao
J
J
Ziki
M
M
Gunn
W
W
Quirk
A
A
Huang
Q S
QS
D000998:Antiviral Agents / Q000494:pharmacology*; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects* / Q000302:isolation & purification; D007251:Influenza, Human / Q000188:drug therapy* / Q000453:epidemiology / Q000821:virology; D008826:Microbial Sensitivity Tests; D009520:New Zealand / Q000453:epidemiology; D053139:Oseltamivir / Q000494:pharmacology*; D011159:Population Surveillance
D000998:Antiviral Agents; D053139:Oseltamivir