title: Pulmonary arterial hypertension complicating adult-onset Still's disease.
abstract: Adult-onset Still's disease (AOSD) is a rare condition diagnosed by a combination of clinical and laboratory features and after ruling out other conditions. Pulmonary manifestations, apart from pleuritis, are uncommon and pulmonary arterial hypertension (PAH) in extremely uncommon. We have described a case of AOSD with severe PAH. There have been rare reports of PAH occurring in AOSD in the literature. Probably, this manifestation may have been understudied, being confined to cases which are symptomatic. A larger study to look at the asymptomatic occurrences of PAH in AOSD may help in unraveling the mystery of this disease.
authors: Department of Rheumatology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India.
authors: Manisha
authors: M
authors: Thakare
authors: Shabina
authors: S
authors: Habibi
authors: Sumeet
authors: S
authors: Agrawal
authors: Gumdal
authors: G
authors: Narsimulu
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D065627:Familial Primary Pulmonary Hypertension; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D035583:Rare Diseases; D016706:Still's Disease, Adult-Onset / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids