title: Idiopathic pulmonary veno-occlusive disease.
abstract: We report a case of idiopathic pulmonary veno-occlusive disease (PVOD). The patient experienced progressively worsening dyspnea. Heart catheterization revealed severe pulmonary hypertension. High-resolution computed tomography (HRCT) showed diffuse, poorly identified centrilobular ground-glass opacities. Surgical lung biopsy led to the diagnosis of PVOD. A microscopic examination revealed occlusions of pulmonary veins and venules over a wide area with prominent loop-like capillary dilatations. These pathological findings may be correlated with the radiological characteristics of HRCT in this case.
authors: Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya. mai-i@med.nagoya-u.ac.jp
authors: Mai
authors: M
authors: Iwaki
authors: Kazuyoshi
authors: K
authors: Imaizumi
authors: Toyoharu
authors: T
authors: Yokoi
authors: Masashi
authors: M
authors: Kondo
authors: Katsuhiro
authors: K
authors: Kawaguchi
authors: Yoshinori
authors: Y
authors: Hasegawa
mesh_terms: D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000503:physiopathology; D008875:Middle Aged; D011667:Pulmonary Veins / Q000473:pathology; D011668:Pulmonary Veno-Occlusive Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed