title: Elucidating the origin of anomalous diffusion in crowded fluids.
abstract: Anomalous diffusion in crowded fluids, e.g., in the cytoplasm of living cells, is a frequent phenomenon. So far, however, the associated stochastic process, i.e., the propagator of the random walk, has not been uncovered. Here we show by means of fluorescence correlation spectroscopy and simulations that the properties of crowding-induced subdiffusion are consistent with the predictions for fractional Brownian motion or obstructed (percolationlike) diffusion, both of which have stationary increments. In contrast, our experimental results cannot be explained by a continuous time random walk with its distinct non-Gaussian propagator.
authors: Cellular Biophysics Group (BIOMS), German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
authors: Jedrzej
authors: J
authors: Szymanski
authors: Matthias
authors: M
authors: Weiss
mesh_terms: D001052:Apoferritins / Q000737:chemistry; D002021:Buffers; D004058:Diffusion; D007424:Intracellular Fluid / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological; D008956:Models, Chemical; D013269:Stochastic Processes
chemical_list: D002021:Buffers; D001052:Apoferritins