High-density lipoprotein-cholesterol trajectory pattern, associated lifestyle and biochemical factors among Taiwanese.
BACKGROUND
Little is known about high-density lipoprotein-cholesterol (HDL-C) trajectory patterns among ethnic Chinese in Taiwan, or the effects of lifestyle and biochemical measurements on these trajectory patterns.


RESULTS
This longitudinal study was based on 330 adult participants who underwent biochemical measurements annually from 2003 to 2006. As time progressed, HDL-C increased significantly; women had a consistently higher value (10 mg/dl) than men. An increase of 1 kg/m(2) in body mass index was associated with -1.00 +/-0.25 mg/dl HDL-C for women (P=0.0001) and -0.78 +/-0.11 mg/dl for men (P<0.0001). Current smoking was inversely associated with HDL-C in men only. Systolic blood pressure and exercise frequency were positively associated with HDL-C in men only. Compared with non-smokers, participants who smoked had a lower HDL-C level of -8.42 +/-4.90 mg/dl in women (P=0.09) and -3.60 +/-0.94 mg/dl in men (P=0.0001). In contrast, a 1-h increase in exercise frequency every week was related to an increased HDL-C level of 0.38 +/-0.28 mg/dl for women (P=0.18) and 0.53 +/-0.14 mg/dl for men (P=0.0001).


CONCLUSIONS
An increase in HDL-C was shown over a 4-year period and gender-specific lifestyle factors were associated with HDL-C concentration among ethnic Chinese in Taiwan.
Lee
Yuan-Chi
YC
Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan.
Chien
Kuo-Liong
KL
Lee
Bai-Chin
BC
Lin
Hung-Ju
HJ
Hsu
Hsiu-Ching
HC
Chen
Ming-Fong
MF
D000367:Age Factors; D044466:Asian People / Q000706:statistics & numerical data; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D015992:Body Mass Index; D002681:China / Q000208:ethnology; D008076:Cholesterol, HDL / Q000097:blood*; D050171:Dyslipidemias / Q000097:blood / Q000208:ethnology* / Q000209:etiology; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style / Q000208:ethnology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000208:ethnology; D013624:Taiwan / Q000453:epidemiology; D013997:Time Factors
D015415:Biomarkers; D008076:Cholesterol, HDL