title: Relationship of prospective memory to neuropsychological function and antiretroviral adherence.
abstract: Prospective memory is defined as the ability to "remember to remember" something at a future time despite intervening distractions and may be particularly important in remembering to take prescribed medication among people infected with HIV. Ninety-seven HIV-positive participants in a clinical trial had their adherence measured by electronic pillcaps and were administered neuropsychological screening tests and the memory for intentions screening test (MIST). Factor analysis of the MIST and other neuropsychological measures identified four factors. Two were derived from MIST subscales and accounted for approximately 50% of the variance in cognitive functioning. Only one factor was significantly correlated with adherence, and this was a MIST factor. In this preliminary study, the MIST assessed a memory function that (a) could be distinguished from traditional retrospective recall and executive functioning and (b) was correlated with antiretroviral adherence.
authors: VA Boston Healthcare System, Neuropsychology Service, Boston, MA 02132, USA. chriscontardo@gmail.com
authors: Christopher
authors: C
authors: Contardo
authors: Anne C
authors: AC
authors: Black
authors: John
authors: J
authors: Beauvais
authors: Kevin
authors: K
authors: Dieckhaus
authors: Marc I
authors: MI
authors: Rosen
mesh_terms: D000328:Adult; D000368:Aged; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000150:complications / Q000523:psychology*; D005260:Female; D006679:HIV Seropositivity / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008568:Memory; D008875:Middle Aged; D009483:Neuropsychological Tests; D019966:Substance-Related Disorders / Q000150:complications
chemical_list: D044966:Anti-Retroviral Agents