Revisiting 23-iodospirostanes. New facts and full characterization.
In addition to a previous report, the reaction of tigogenin acetate with ICl in refluxing CHCl(3) produced the hitherto unknown 23R-iodotigogenin acetate, bearing an axial iodine atom at C-23 and its already reported 23S-epimer. The same treatment of sarsasapogenin acetate led to a single diasteromer characterized as 23S-iodosarsasapogenin acetate. A full characterization of the obtained compound including (1)H, (13)C NMR, MS and X-ray diffraction is provided.
Ruíz-Pérez
Karen M
KM
Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510 México, D.F., Mexico.
Romero-Avila
Margarita
M
Flores-Pérez
Blas
B
Flores-Alamo
Marcos
M
Moreno-Esparza
Rafael
R
Iglesias-Arteaga
Martín A
MA
D018360:Crystallography, X-Ray; D007455:Iodine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D013150:Spirostans / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
D013150:Spirostans; D007455:Iodine