Paramagnetic Gd-based gold glyconanoparticles as probes for MRI: tuning relaxivities with sugars.
Combining sugar conjugates and DO3A-Gd complexes, paramagnetic gold glyconanoparticles (GNPs) with different relaxivity values were obtained and tested in vivo as MRI probes.
Marradi
Marco
M
Laboratory of GlycoNanotechnology, CIC biomaGUNE/CIBER-BBN and IIQ-CSIC, Parque Tecnológico de San Sebastián, San Sebastián, Spain.
Alcántara
David
D
de la Fuente
Jesús Martínez
JM
García-Martín
María Luisa
ML
Cerdán
Sebastián
S
Penadés
Soledad
S
D000818:Animals; D002241:Carbohydrates / Q000737:chemistry; D005682:Gadolinium / Q000737:chemistry*; D005910:Glioma / Q000175:diagnosis*; D006046:Gold / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry
D002241:Carbohydrates; D006046:Gold; D005682:Gadolinium