title: [Botulism in dairy cattle in 2008: symptoms, diagnosis, pathogenesis, therapy, and prevention].
abstract: Botulism affects about 20 dairy herds a year in the Netherlands. This article describes the dramatic outcome of botulism in a dairy herd. The main clinical symptoms in this herd were increased lying down, slight ataxia of the hind legs, and a high mortality (98%). The diagnosis is difficult to establish in adult cattle, and for this reason the clinical and laboratory findings, differential diagnosis, therapy, and preventive measures are discussed. On the basis of this outbreak, previous experience with botulism, and cases described in literature, it is suggested that presence of 'free-range" poultry could contaminate grazing pastures with botulism neurotoxins, causing clinical problems in cattle. If there is an increased risk of contamination of the pasture and/or silage with botulinum neurotoxins, vaccination should be considered to prevent substantial economic and emotional damage.
authors: m.holzhauer@gddeventer.com
authors: M
authors: M
authors: Holzhauer
authors: H I J
authors: HI
authors: Roest
authors: M G
authors: MG
authors: de Jong
authors: J H
authors: JH
authors: Vos
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage; D001905:Botulinum Toxins / Q000506:poisoning*; D001906:Botulism / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000401:mortality / Q000517:prevention & control / Q000628:therapy; D003612:Dairying / Q000379:methods*; D003937:Diagnosis, Differential; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary; D005260:Female; D005506:Food Contamination / Q000517:prevention & control; D009426:Netherlands / Q000453:epidemiology
chemical_list: D001428:Bacterial Vaccines; D001905:Botulinum Toxins