title: Metabolic acidosis at birth and suboptimal care--illustration of the gap between knowledge and clinical practice.
abstract: OBJECTIVE
  To evaluate the occurrence and nature of suboptimal intrapartum care in cases with metabolic acidosis in the newborn, and to estimate the degree to which this may be prevented.
  
  
  METHODS
  Case-control study. Clinical audit. Setting Delivery units at two university hospitals in Sweden.
  
  
  METHODS
  Out of 28 486 deliveries, 161 neonates > or =34 weeks of gestational age were born with metabolic acidosis.
  
  
  METHODS
  Cases (n = 161): umbilical artery pH < 7.05 and base deficit > or =12 mmol/l. Controls (n = 322): pH > or = 7.05 and Apgar score > or =7 at 5 minutes. Obstetric characteristics and oxytocin administration were recorded. The last 2 hours of electronic fetal monitoring before delivery were evaluated blinded to outcome. Intrapartum management was analysed for suboptimal care by using predefined criteria.
  
  
  METHODS
  Suboptimal intrapartum care.
  
  
  RESULTS
  Case and control comparisons displayed an occurrence of suboptimal care in 49.1% versus 13.0% (P < 0.001), oxytocin misuse in 46.6% versus 13.0% (P < 0.001), a failure to respond to a pathological cardiotocographic pattern in 19.9% versus 1.2% (P < 0.001) and suboptimal care related to vacuum deliveries in 3.1% versus 0.3% (P < 0.01) respectively.
  
  
  CONCLUSIONS
  Metabolic acidosis at birth is often associated with suboptimal intrapartum care. The high rate of suboptimal care with regard to oxytocin use and fetal surveillance illustrate a gap between guidelines and clinical practice. Metabolic acidosis and related neonatal morbidity could potentially be prevented in 40-50% of cases. The adherence to guidelines must be checked.
authors: Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. maria.jonsson@kbh.uu.se
authors: M
authors: M
authors: Jonsson
authors: S
authors: S
authors: Nordén-Lindeberg
authors: I
authors: I
authors: Ostlund
authors: U
authors: U
authors: Hanson
mesh_terms: D000138:Acidosis / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015148:Cardiotocography / Q000592:standards; D016022:Case-Control Studies; D002983:Clinical Competence; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008427:Maternal Health Services / Q000592:standards; D008485:Medical Audit; D010120:Oxytocics / Q000008:administration & dosage / Q000009:adverse effects; D010121:Oxytocin / Q000008:administration & dosage / Q000009:adverse effects; D018743:Perinatal Care / Q000592:standards*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D013548:Sweden / Q000453:epidemiology
chemical_list: D010120:Oxytocics; D010121:Oxytocin