Bacteraemia as a result of Campylobacter species: a population-based study of epidemiology and clinical risk factors.
Invasive disease as a result of Campylobacter is rarely reported. We reviewed 46 cases of blood stream infection with Campylobacter in a Danish population with complete follow-up. The incidence was 2.9 per 1 million person-years with a peak incidence in the age group above 80 years. In the population, the ratio of notified bacteraemia/enteritis patients with Campylobacter infection was 0.004. Patients with bacteraemia were older and had higher comorbidity, e.g. alcoholism, immunosuppression, previous gastrointestinal surgery or HIV infection. We found 26% of blood isolates resistant to ciprofloxacin. The length of hospitalization was significantly longer in bacteraemia patients, whereas the outcome was favourable with 28-day mortality of 4% in bacteraemia patients and 1% in enteritis patients. None of the bacteraemia patients relapsed within 365-day follow-up.
Nielsen
H
H
Department of Infectious Diseases, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark. henrik.nielsen@rn.dk
Hansen
K K
KK
Gradel
K O
KO
Kristensen
B
B
Ejlertsen
T
T
Østergaard
C
C
Schønheyder
H C
HC
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D002167:Campylobacter / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D003718:Denmark / Q000453:epidemiology; D004751:Enteritis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D018709:Statistics, Nonparametric
D000900:Anti-Bacterial Agents