title: Sc(OTf)(3)-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: an efficient synthesis of 5-alkyl-1,3-oxazolidines.
abstract: Sc(OTf)(3) effectively catalyzes the condensation of 2-alkyl-N-tosylaziridine with a wide variety of aldehydes and ketones, producing 5-alkyl-1,3-oxazolidines in good yields and excellent regioselectivity at catalyst loadings as low as 1 mol%.
authors: Department of Chemistry and the Institute for Catalysis in Energy Processes, Northwestern University, Evanston, IL 60208-3113, USA.
authors: Byungman
authors: B
authors: Kang
authors: Aaron W
authors: AW
authors: Miller
authors: Sandra
authors: S
authors: Goyal
authors: SonBinh T
authors: ST
authors: Nguyen
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000473:Alkanes / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*; D012538:Scandium / Q000737:chemistry*; D013237:Stereoisomerism; D014105:Tosyl Compounds / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000473:Alkanes; D001388:Aziridines; D007659:Ketones; D008698:Mesylates; D010080:Oxazoles; D014105:Tosyl Compounds; C436603:scandium triflate; C033132:aziridine; D012538:Scandium