[Metabolic fingerprinting of blood plasma for patients with prostate cancer].
Application of blood plasma metabolites fingerprinting for the diagnostic of the 2nd stage of prostate cancer has been investigated. The diagnostic sensitivity (95%), specificity (96.7%) and accuracy (95.7%) of the metabolic fingerprinting were much higher then those for PSA test (35%, 83.3% and 51.7%, respectively) for the same patients. Area under the ROC-curve (0.994) suggests that the proposed approach is effective and can be used for clinical applications.
Lokhov
P G
PG
Dashtiev
M I
MI
Bondartsov
L V
LV
Lisitsa
A V
AV
Moshkovskiĭ
S A
SA
Archakov
A I
AI
D014408:Biomarkers, Tumor / Q000097:blood*; D001798:Blood Proteins / Q000032:analysis*; D006801:Humans; D008297:Male; D055442:Metabolome; D011471:Prostatic Neoplasms / Q000097:blood* / Q000175:diagnosis; D012372:ROC Curve; D021241:Spectrometry, Mass, Electrospray Ionization
D014408:Biomarkers, Tumor; D001798:Blood Proteins