title: Acquired ichthyosis as a paraneoplastic syndrome in Hodgkin's disease.
abstract: An 80-year-old man was admitted to hospital with low-grade fever, weight loss, asthenia and anorexia. Physical examination revealed generalised ichthyosis with palmoplantar hyperkeratosis. CT scan showed retroperitoneal and inguinal lymph node enlargement. An inguinal lymph node biopsy revealed Hodgkin's disease (nodular-sclerosing subtype). The patient received chemotherapy, showing a clear improvement of both skin lesions and lymph nodes.
authors: Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón Madrid, Spain.
authors: María Carmen
authors: MC
authors: Riesco Martínez
authors: Andrés J
authors: AJ
authors: Muñoz Martín
authors: Pamela
authors: P
authors: Zamberk Majlis
authors: Jorge
authors: J
authors: Adeva Alfonso
authors: Pilar
authors: P
authors: Sabin Domínguez
authors: Pilar
authors: P
authors: García Alfonso
authors: Ricardo
authors: R
authors: Pérez Fernández
mesh_terms: D000369:Aged, 80 and over; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000473:pathology