[Pulmonary Ewing sarcoma/primitive neuroectodermal tumor: a case report and a review of the literature].
Primary thoracic sarcomas are very rare. The most common intrathoracic variants are synovial sarcoma, angiosarcoma, leiomyosarcoma, rhabdomyosarcoma, and sarcomatoid mesothelioma. Although thoracic Ewing sarcoma/primitive neuroectodermal tumor (PNET) usually develops on the chest wall, there have been reports of primary Ewing sarcoma/PNET of the lung. We present the case of a 22-year-old woman with Ewing sarcoma/PNET diagnosed following histologic, immunohistochemical, and in situ hybridization studies of a bronchial biopsy specimen. Radiography, ventilation-perfusion scintigraphy, and a bone marrow biopsy confirmed that the tumor was not metastatic. The patient was started on a chemotherapy regimen of vincristine, actinomycin, cyclophosphamide, doxorubicin, ifosfamide, and etoposide and responded well. She is now being seen regularly at our outpatient clinic.
Suárez Antelo
Juan
J
Servicio de Neumología, Complejo Hospitalario Universitario, A Coruña, Spain. jsuaant@telefonica.net
Rodríguez García
Carlota
C
Montero Martínez
Carmen
C
Verea Hernando
Héctor
H
D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D018242:Neuroectodermal Tumors, Primitive / Q000175:diagnosis / Q000188:drug therapy; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000188:drug therapy; D055815:Young Adult