Unraveling the human embryonic stem cell phosphoproteome.
The human embryonic stem cell (hESC) transcriptome is well described, but minimal proteome characterization is available. In this issue of Cell Stem Cell, Brill et al. (2009) and Van Hoof et al. (2009) describe the hESC phosphoproteome and its changes upon differentiation.
Hutchins
Andrew P
AP
Stem Cell & Developmental Biology, Genome Institute of Singapore, Singapore, Singapore.
Robson
Paul
P
D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000378:metabolism*; D020869:Gene Expression Profiling; D006801:Humans; D010750:Phosphoproteins / Q000378:metabolism*; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D020543:Proteome / Q000378:metabolism*
D010750:Phosphoproteins; D020543:Proteome; D011494:Protein Kinases