Human leukocyte antigen-G polymorphism in relation to expression, function, and disease.
Human leukocyte antigen-G (HLA-G) is a nonclassical class Ib molecule belonging to the major histocompatibility complex. HLA-G appears to play a role in the suppression of immune responses and contribute to long-term immune escape or tolerance. The focus of this review is polymorphism in the HLA-G gene and protein and its possible importance in expression, function, and disease associations.
Larsen
Margit Hørup
MH
Department of Clinical Biochemistry, Roskilde University Hospital, Roskilde, Denmark.
Hviid
Thomas Vauvert F
TV
D020413:3' Untranslated Regions / Q000235:genetics; D000483:Alleles; D001249:Asthma / Q000235:genetics; D001327:Autoimmune Diseases / Q000235:genetics; D004194:Disease / Q000235:genetics*; D005091:Exons / Q000235:genetics; D005260:Female; D006680:HLA Antigens / Q000145:classification / Q000235:genetics* / Q000502:physiology*; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000145:classification / Q000235:genetics* / Q000502:physiology*; D006801:Humans; D015810:Linkage Disequilibrium; D016377:Organ Transplantation; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000235:genetics; D012045:Regulatory Sequences, Nucleic Acid
D020413:3' Untranslated Regions; D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I