Diffuse corneoscleral limbal neuromas with prominent corneal nerves in multiple endocrine neoplasia syndrome type IIB.
This report describes a 7-year-old boy with multiple endocrine neoplasia type 2B who presented to the ophthalmology department because of peripheral corneal changes. In addition to prominent corneal nerves and eyelid neuromas, the patient was found to have substantial corneoscleral limbal thickening with corneal neovascularization.
Puvanachandra
Narman
N
BC Children's Hospital, Pediatric Ophthalmology Department, Vancouver, BC, Canada.
Aroichane
Maryam
M
D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D016850:Limbus Corneae / Q000294:innervation / Q000473:pathology*; D008297:Male; D018814:Multiple Endocrine Neoplasia Type 2b / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009412:Nerve Fibers / Q000473:pathology*; D009463:Neuroma / Q000175:diagnosis*; D012590:Sclera / Q000294:innervation / Q000473:pathology*