title: Bell's palsy and choreiform movements during peginterferon alpha and ribavirin therapy.
abstract: Neuropsychiatric side effects of long-term recombinant interferon-alpha therapy consist of a large spectrum of symptoms. In the literature, cranial neuropathy, especially Bell's palsy, and movement disorders, have been reported much less often than other neurotoxic effects. We report a case of Bell's palsy in a patient with chronic hepatitis C during peginterferon-alpha and ribavirin therapy. The patient subsequently developed clinically inapparent facial nerve involvement on the contralateral side and showed an increase in choreic movements related to Huntington's disease during treatment.
authors: Department of Infectious Diseases and Clinical Microbiology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. senerbarut@yahoo.com
authors: Sener
authors: S
authors: Barut
authors: Hatice
authors: H
authors: Karaer
authors: Erol
authors: E
authors: Oksuz
authors: Asli Gündoğdu
authors: AG
authors: Eken
authors: Ayse Nazli
authors: AN
authors: Basak
mesh_terms: D000998:Antiviral Agents / Q000009:adverse effects*; D020330:Bell Palsy / Q000139:chemically induced*; D002819:Chorea / Q000139:chemically induced*; D005260:Female; D006526:Hepatitis C / Q000188:drug therapy; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects*; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000009:adverse effects*; D011994:Recombinant Proteins; D012254:Ribavirin / Q000009:adverse effects
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C417083:peginterferon alfa-2b