[Kidney sicknesses associated with gene of the drepanocytose in the Department of Nephrology and Haemodialysis of the CHU of Point G].
OBJECTIVE
To assess renal features joint to gene of the drepanocytose.


METHODS
It concerned a descriptive transversal study from June 1995 to January 2004. Were included drepanocytose patients admitted hospital or seeing for consulting having one of the features: haematuria, proteinuria, leucocyturia, positive aeroculture, urea increasing and/ or of blood creatinine. The analysis and data capture were conducted on SPSS 11.0. The statistic text was the Khi square with a threshold of signification p<0.05.


RESULTS
The folders of 30 patients (18 m and 12 w) were collected. The average age was of 3104 years (5 and 64 years). The most hospitalization reasons encountered were the oedema syndrome (26.7%) and the overall haematuria (20%). The majority of the patients were heterozygote 93.33%. The kidney sicknesses encountered were: acute renal deficiency 40%, the macroscopic haematuria 20%, the nephritic syndrome 20%, chronic renal deficiency 13.4%, urinary infection 3.3% and microscopic haematuria 33%.


CONCLUSIONS
The sicklaneny's gene in Mali is associated to a renal morbidity. The increased frequency of drepanocytaria feature bearers must be confirmed by other studies in order to establish a strategic of treatment of this pathology.
Fongoro
S
S
Service de Néphrologie et d'Hémodialyse, CHU du Point G.
Diallo
D
D
Diallo
D A
DA
Tchiango
K A
KA
Maiga
M K
MK
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009398:Nephrology; D006435:Renal Dialysis; D014573:Urology Department, Hospital; D055815:Young Adult
D006451:Hemoglobin, Sickle