Erectile dysfunction after radiotherapy for prostate cancer.
Erectile Dysfunction (ED) is a relatively common complication after radiotherapy for prostate cancer. The etiology of ED is unclear. It is likely related to age, pretreatment erectile function, androgen deprivation therapy, and the volume of tissue irradiated. It is unclear whether the dose to various parts of the penis, such as the penile bulb and corpora cavernosa, is related to the development of ED. Following radiotherapy, the early use of phosphodiesterase inhibitors probably reduces the risk of ED.
Mendenhall
William M
WM
Department of Radiation Oncology, University of Florida Health Science Center, 2000 SW Archer Rd, PO Box 100385 Gainesville, FL 32610-0385, USA. mendwm@shands.ufl.edu
Henderson
Randal H
RH
Indelicato
Daniel J
DJ
Keole
Sameer R
SR
Mendenhall
Nancy P
NP
D017677:Age Distribution; D000368:Aged; D004307:Dose-Response Relationship, Radiation; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000009:adverse effects* / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index