[Characteristics of intrinsic laryngeal muscle after recurrent laryngeal nerve injury].
OBJECTIVE
To investigate the electrophysiological characteristics and pathological changes in different recurrent laryngeal nerve injury models.


METHODS
Twenty dogs were divided into different models of recurrent laryngeal nerve injury. Electrophysiological changes of animal models and histopathological changes in laryngeal muscles were investigated at different time.


RESULTS
Amplitude of MUP in TA decreased at first and then increased a little, while duration of MUP keeps decreased. The latent periods of the evoked potential in the incomplete injury group increased at first and then went down. In animal histopathological investigation, the lighter of the muscle injuries and the bigger of the diameter of muscle fibers and fascicles, and the smaller of the number of cellular nucleolus per square inch. In the early periods after injury, the correlation among the standard amplitude, threshold amplitude, maximum amplitude of EP and the diameter of fascicles were positive; while in the late period, the correlation among the amplitude, duration, area of MUP and nucleolus number was positive.


CONCLUSIONS
The physiological characteristics of laryngeal nerves and muscles could be known. LEMG was an important method in diagnosis of laryngeal nerve and muscle diseases.
Xu
Wen
W
Department of Otorhinolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. entwen@trhos.com
Zhao
Gongwei
G
Hu
Huiying
H
Fan
Erzhong
E
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004576:Electromyography; D005071:Evoked Potentials; D007821:Laryngeal Muscles / Q000294:innervation / Q000503:physiopathology*; D061226:Recurrent Laryngeal Nerve Injuries