Two new phenylglycol derivatives isolated from Syringa reticulata var. mandshurica and their antifungal activities.
Two new phenylglycol derivatives, (S)-(+)-2-(3,4-dihydroxy phenyl)-2-ethoxyl- ethanol and (S)-(+)-2-(3,4-dihydroxy phenyl)-2-acetoxy-ethanol, were isolated from the leaves of Syringa reticulata var. mandshurica, along with two known phenethylols, p-hydroxyl phenethanol and 3,4-dihydroxy phenethanol. The planar structures of the new compounds were established on the basis of their spectral data, and their absolute stereochemistry was established by modified Mosher's method. The two known compounds were identified by comparison of spectral data with published references. The two new compounds showed conspicuous antifungal activities by agar medium assay.
Xu
Qiong Ming
QM
College of Pharmacy, Soochow University, Suzhou, China.
Liu
Yan Li
YL
Li
Xiao Ran
XR
Feng
Yu Lin
YL
Yang
Shi Lin
SL
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D002396:Catechols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010838:Phytophthora / Q000187:drug effects* / Q000254:growth & development; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D012015:Reference Standards; D013237:Stereoisomerism; D031662:Syringa / Q000737:chemistry*
C543287:2-(3,4-dihydroxyphenyl)-2-acetoxyethanol; C543286:2-(3,4-dihydroxyphenyl)-2-ethoxyethanol; D000935:Antifungal Agents; D002396:Catechols; D010936:Plant Extracts; D010626:Phenylethyl Alcohol