title: Psychobehavioral predictors of somatoform disorders in patients with suspected allergies.
abstract: OBJECTIVE
  To explore a combination of health-related psychobehavioral features as potential positive criteria for somatoform disorders (SFD). Currently, SFD can only be diagnosed in the absence of sufficient organic symptom explanation, resulting in low criterion validity and delay of appropriate therapy.
  
  
  METHODS
  Cross sectionally, we studied various psychobehavioral characteristics of 197 inpatients with suspected allergies. At the beginning of the medical work-up, patients were interviewed and completed a set of self-rating questionnaires (Illness Perception Questionnaire-Revised, Whiteley Index-7, Cognitions About Body And Health Questionnaire, Scale for the Assessment of Illness Questionnaire, Health Attitude Survey, Reassurance Questionnaire, and Patient Health Questionnaire). Organic explicability of the presenting symptoms was assessed by allergists at the end of the work-up. Forty-eight patients with SFD were compared with 149 patients without SFD, and predictive models were set up. To control for effects of the work-up situation, we also investigated 47 patients with an established diagnosis of hymenoptera venom allergy.
  
  
  RESULTS
  In the work-up group, various self-reported psychobehavioral features discriminated patients with SFD from patients without SFD. In logistic regression analysis, self-reported dissatisfaction with medical care, disease conviction, reduced symptom controllability, and reduced body scanning independently predicted SFD. A predictive model based on these psychobehavioral characteristics had high sensitivity and specificity (area under the curve = 0.86, 95% Confidence Interval = 0.79-0.93; p < .001), which was comparable to the Patient Health Questionnaire-15, an established SFD screening tool assessing somatization.
  
  
  CONCLUSIONS
  Psychobehavioral characteristics in patients with SFD cannot solely be attributed to the uncertainty of a work-up situation. Their predictive value is comparable to that of the traditional measuring of symptom number and severity; hence, they should be considered as SFD positive criteria in Diagnostic and Statistic Manual of Mental Disorders, 5th Edition.
authors: Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Langerstrasse 3, 81675 Muenchen, Germany. c.hausteiner@lrz.tum.de
authors: Constanze
authors: C
authors: Hausteiner
authors: Susanne
authors: S
authors: Bornschein
authors: Esther
authors: E
authors: Bubel
authors: Sylvie
authors: S
authors: Groben
authors: Claas
authors: C
authors: Lahmann
authors: Martine
authors: M
authors: Grosber
authors: Bernd
authors: B
authors: Löwe
authors: Florian
authors: F
authors: Eyer
authors: Bernadette
authors: B
authors: Eberlein
authors: Heidrun
authors: H
authors: Behrendt
authors: Ulf
authors: U
authors: Darsow
authors: Johannes
authors: J
authors: Ring
authors: Peter
authors: P
authors: Henningsen
authors: Dorothea
authors: D
authors: Huber
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001180:Arthropod Venoms / Q000276:immunology; D001294:Attitude to Health; D015897:Comorbidity; D003430:Cross-Sectional Studies; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005858:Germany / Q000453:epidemiology; D006304:Health Status; D006801:Humans; D006927:Hymenoptera / Q000276:immunology; D006967:Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D012720:Severity of Illness Index; D013001:Somatoform Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D011795:Surveys and Questionnaires
chemical_list: D001180:Arthropod Venoms