title: High seroprevalence of caseous lymphadenitis in Brazilian goat herds revealed by Corynebacterium pseudotuberculosis secreted proteins-based ELISA.
abstract: We conducted a seroepidemiological survey to determine the prevalence of caseous lymphadenitis (CLA) in goat herds in Minas Gerais state, Brazil. Serum samples were collected from goats (n=676) from 108 rural properties in 2001, covering most of the sub-regions of this ca. 586,500 square kilometer state. Antibodies against Corynebacterium pseudotuberculosis secreted proteins were detected by an indirect enzyme-linked immunosorbent assay (ELISA). Most of the animals (78.9%) tested positive for CLA; 98% of flocks presented at least one seropositive animal. Goats managed under an extensive production system had a significantly higher seroprevalence of CLA than those in intensive and semi-intensive operations. The age distribution of the animals in the flocks affected the prevalence of this disease; however, goat breed did not. We found seropositivity against C. pseudotuberculosis to be highly prevalent in these Brazilian goat herds; consequently, appropriate management practices for the control of CLA should be implemented.
authors: Laboratório de Genética Celular e Molecular, Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, CP 486, CEP 31270-901, Belo Horizonte, MG, Brazil.
authors: N
authors: N
authors: Seyffert
authors: A S
authors: AS
authors: Guimarães
authors: L G C
authors: LG
authors: Pacheco
authors: R W
authors: RW
authors: Portela
authors: B L
authors: BL
authors: Bastos
authors: F A
authors: FA
authors: Dorella
authors: M B
authors: MB
authors: Heinemann
authors: A P
authors: AP
authors: Lage
authors: A M G
authors: AM
authors: Gouveia
authors: R
authors: R
authors: Meyer
authors: A
authors: A
authors: Miyoshi
authors: V
authors: V
authors: Azevedo
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology; D001938:Brazil / Q000453:epidemiology; D003354:Corynebacterium Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D016925:Corynebacterium pseudotuberculosis; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D006041:Goats / Q000382:microbiology; D008199:Lymphadenitis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D016036:Seroepidemiologic Studies
chemical_list: D001426:Bacterial Proteins