Examination of reinforcement magnitude on the pharmacological disruption of fixed-ratio performance.
Behavioral momentum theory proposes that operant behavior is the product of two separable processes: its rate of occurrence and its resistance to change. Generally speaking, operant situations providing more densely spaced or greater magnitudes of reinforcement should be more resistant to disruption. Attempts to disrupt ongoing behavior by manipulating the availability of food or deprivation level typically have supported the predictions of behavioral momentum. Tests with pharmacological disruptors, however, have yielded mixed results. Most investigations of pharmacological disruption of operant behavior have evaluated momentum across situations that differ in rate of reinforcement. The present experiment was an attempt to systematically replicate prior work, but under conditions of differing reinforcement magnitudes. Pigeons were trained to key peck on a multiple fixed-ratio 30 schedule of food presentation, where different components programmed 2-, 4-, or 8-s access to grain. Resistance to rate-decreasing effects of drugs was evaluated with several compounds drawn from distinct pharmacological classes: chlordiazepoxide, cocaine, clonidine, haloperidol, morphine, and ethanol were tested. Additionally, disruption by prefeeding and extinction was examined. Generally, resistance to change by drug administration was not modulated by reinforcement magnitude. Prefeeding and extinction tests, however, replicated previous work, indicating that our procedure was sensitive to more common disruptors. The results give additional support to the notion that pharmacological disruptors may not behave in the manner predicted by behavioral momentum theory.
Pinkston
Jonathan W
JW
Universityof Texas Health Science Center, Department of Psychiatry, San Antonio, TX 78229, USA. pinkstonj@uthscsa.edu
Ginsburg
Brett C
BC
Lamb
R J
RJ
D000818:Animals; D002707:Chlordiazepoxide / Q000494:pharmacology; D003000:Clonidine / Q000494:pharmacology; D003042:Cocaine / Q000494:pharmacology; D010856:Columbidae; D003216:Conditioning, Operant / Q000187:drug effects*; D000431:Ethanol / Q000494:pharmacology; D005108:Extinction, Psychological; D005508:Food Deprivation; D006220:Haloperidol / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology; D012055:Reinforcement Schedule; D012054:Reinforcement, Psychology; D013997:Time Factors
D000431:Ethanol; D002707:Chlordiazepoxide; D009020:Morphine; D003042:Cocaine; D006220:Haloperidol; D003000:Clonidine