title: Effect of sodium hypochlorite on dentine mechanical properties. A review.
abstract: OBJECTIVE
  The aim of this study was to carry out a review on the effect of sodium hypochlorite (NaOCl) on the mechanical properties of root dentine.
  
  
  METHODS
  The authors searched the Cochrane Library, Embase, PubMed and the Web of Science for papers published from 1984 to 2008. The main search terms used were: dentine, root canal dentine, sodium hypochlorite, mechanical analysis, elastic modulus, hardness, roughness, flexural strength, compressive strength.
  
  
  METHODS
  The inclusion criteria were studies that evaluated the effect of NaOCl solution, used as an irrigant in endodontics, on the mechanical properties of root dentine. Those studies that were considered to be unrelated to the question addressed, that had investigated NaOCl as a deproteinizing agent, had not evaluated the effect of NaOCl on the mechanical properties of dentine, and that indirectly verified the effect of NaOCl on endodontically treated teeth were excluded. The selected papers were assigned to a score (A-C), according to predetermined criteria. A total of 16 papers were selected, and nine papers were included in the critical appraisal. Five papers were classified as grade A, 4 as grade B, and no paper was classified as grade C.
  
  
  CONCLUSIONS
  Based on this review, the authors suggest that there is strong evidence showing that sodium hypochlorite adversely alters the mechanical properties of root dentine, when used as an endodontic irrigant.
authors: Pediatric Dentistry Department, Piracicaba Dental School, State University of Campinas, Avenida Limeira 901 Areião, Piracicaba, São Paulo, Brazil.
authors: Fernanda Miori
authors: FM
authors: Pascon
authors: Kamila Rosamilia
authors: KR
authors: Kantovitz
authors: Patrícia Almada
authors: PA
authors: Sacramento
authors: Marinês
authors: M
authors: Nobre-dos-Santos
authors: Regina Maria
authors: RM
authors: Puppin-Rontani
mesh_terms: D001696:Biomechanical Phenomena / Q000187:drug effects; D003786:Dental Pulp Cavity / Q000187:drug effects*; D003804:Dentin / Q000187:drug effects*; D006801:Humans; D055595:Mechanical Phenomena / Q000187:drug effects; D012388:Root Canal Irrigants / Q000494:pharmacology*; D012973:Sodium Hypochlorite / Q000494:pharmacology*
chemical_list: D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite