title: Safe and probably safe drugs in acute hepatic porphyria.
abstract: Acute porphyrias are caused by enzyme defects along the heme synthesis pathway. Patients usually present with abdominal pain, impaired intestinal motility, neurological and psychiatric symptoms, hypertension, tachycardia, hyponatriemia and reddish urine. This article gives an overview over drugs that are recommended in patients with acute hepatic porphyrias and represents a compilation of four so far existing lists.
authors: Porphyria Center Saxony, Medizinische Klinik II, Klinikum Chemnitz. u.stoelzel@skc.de
authors: U
authors: U
authors: Stölzel
authors: C
authors: C
authors: Brosche
authors: C
authors: C
authors: Koszka
authors: T
authors: T
authors: Stauch
authors: A
authors: A
authors: Teubner
authors: M O
authors: MO
authors: Doss
mesh_terms: D000624:5-Aminolevulinate Synthetase / Q000037:antagonists & inhibitors / Q000378:metabolism; D001120:Arginine / Q000627:therapeutic use; D064420:Drug-Related Side Effects and Adverse Reactions; D006418:Heme / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D016031:Liver Transplantation; D017118:Porphyria, Acute Intermittent / Q000628:therapy*
chemical_list: D006418:Heme; D001120:Arginine; D000624:5-Aminolevulinate Synthetase; C048849:heme arginate