17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry.
Flory
James H
JH
Sleiman
Patrick M
PM
Christie
Jason D
JD
Annaiah
Kiran
K
Bradfield
Jonathan
J
Kim
Cecilia E
CE
Glessner
Joseph
J
Imielinski
Marcin
M
Li
Hongzhe
H
Frackelton
Edward C
EC
Cuiping
Hou
H
Otieno
George
G
Thomas
Kelly
K
Smith
Ryan
R
Glaberson
Wendy
W
Garris
Maria
M
Chiavacci
Rosetta
R
Allen
Julian
J
Spergel
Jonathan
J
Grundmeier
Robert
R
Grunstein
Michael
M
Magnusson
Michael
M
Grant
Struan F A
SF
Bønnelykke
Klaus
K
Bisgaard
Hans
H
Hakonarson
Hakon
H
D000293:Adolescent; D001249:Asthma / Q000453:epidemiology* / Q000235:genetics*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D015331:Cohort Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D014026:Nicotiana / Q000009:adverse effects*; D044465:White People / Q000235:genetics
D008565:Membrane Proteins; C464399:ORMDL3 protein, human