title: Predictive factors associated with the reversibility of post-transplantation diabetes mellitus following liver transplantation.
abstract: Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persistent PTDM patients, they were characterized by younger age at the time of transplantation (49+/-7 vs. 53+/-8 yr, P<0.05), longer time before the development of PTDM (44+/-59 vs. 13+/-20 days, P<0.05), lower rate of hepatitis c virus seropositivity (0.0 vs. 9.4%, P<0.05), and use of mycophenolate mofetil (59.5 vs. 28.1%, P<0.05). Among these risk factors, age at the time of transplantation is the single independent predictive factor associated with the reversibility of PTDM.
authors: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors: Hwa Young
authors: HY
authors: Ahn
authors: Young Min
authors: YM
authors: Cho
authors: Nam-Joon
authors: NJ
authors: Yi
authors: Kyung Suk
authors: KS
authors: Suh
authors: Kuhn Uk
authors: KU
authors: Lee
authors: Kyong Soo
authors: KS
authors: Park
authors: Seong Yeon
authors: SY
authors: Kim
authors: Hong Kyu
authors: HK
authors: Lee
mesh_terms: D000328:Adult; D000367:Age Factors; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D011237:Predictive Value of Tests; D015995:Prevalence; D012307:Risk Factors
chemical_list: D009173:Mycophenolic Acid