title: Onset of breast and pubic hair development and menses in urban chinese girls.
abstract: OBJECTIVE
  To determine the current prevalence and mean ages of onset of pubertal characteristics in healthy urban Chinese girls.
  
  
  METHODS
  A cross-sectional study of sexual maturation of healthy Chinese girls was conducted in 9 representative cities of the eastern, western, southern, and northern parts and central region of China between 2003 and 2005. At examination, stages of breast and pubic hair development were rated on girls 3 through 19.83 years of age, and height and weight were also recorded. Data on menses were collected by the status quo method. Probit analysis was used to calculate the median age and 95% confidence interval (CI) for onset of breast and pubic hair development and menarche.
  
  
  RESULTS
  Data were analyzed for 20654 apparently healthy girls. At age 8 years, 19.57% of these girls had evidence of breast development. The median ages of onset of Tanner stages 2 and 3 for breast development were 9.20 (95% CI: 9.06-9.32) years and 10.37 (95% CI: 10.28-10.45) years, respectively. The median ages of onset of Tanner stages 2 and 3 for pubic hair development were 11.16 (95% CI: 11.03-11.29) years and 12.40 (95% CI: 12.25-12.55) years, respectively. Menses occurred at 12.27 years (95% CI: 12.16-12.39).
  
  
  CONCLUSIONS
  These data suggest that urban Chinese girls are actually experiencing earlier breast development than currently used norms. The up-to-date reference for normal pubertal development in urban Chinese girls needs to be established for the purpose of determining precocious puberty or pubertal delay.
authors: Department of Pediatrics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China. mahuamei@tom.com
authors: Hua-Mei
authors: HM
authors: Ma
authors: Min-Lian
authors: ML
authors: Du
authors: Xiao-Ping
authors: XP
authors: Luo
authors: Shao-Ke
authors: SK
authors: Chen
authors: Li
authors: L
authors: Liu
authors: Rui-Min
authors: RM
authors: Chen
authors: Cheng
authors: C
authors: Zhu
authors: Feng
authors: F
authors: Xiong
authors: Tang
authors: T
authors: Li
authors: Wei
authors: W
authors: Wang
authors: Ge-Li
authors: GL
authors: Liu
mesh_terms: D000293:Adolescent; D000367:Age Factors; D044466:Asian People / Q000706:statistics & numerical data*; D001827:Body Height; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D002681:China; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008572:Menarche; D012016:Reference Values; D012727:Sex Characteristics; D012741:Sexual Maturation; D014505:Urban Population / Q000706:statistics & numerical data*