title: Palladium-catalysed enantioselective alpha-hydroxylation of beta-ketoesters.
abstract: Highly enantioselective alpha-hydroxylation of cyclic and acyclic 1,3-ketoesters can be achieved with up to 98% ee using a dicationic palladium(ii) catalyst and dimethyldioxirane as oxidant.
authors: Department of Chemistry, Imperial College London, South Kensington, London, UK.
authors: Alexander M R
authors: AM
authors: Smith
authors: Denis
authors: D
authors: Billen
authors: King Kuok Mimi
authors: KK
authors: Hii
mesh_terms: D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry*; D006900:Hydroxylation; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004952:Esters; D007659:Ketones; D010165:Palladium