New catalytic properties of iron complexes: dehydration of amides to nitriles.
Various iron carbonyl clusters such as Fe2(CO)9 or [Et3NH][HFe3(CO)11] are shown to catalyze the dehydration of amides into the corresponding nitriles in the presence of silanes in high yields; this novel protocol showed good functional group tolerance and wide substrate scope.
Zhou
Shaolin
S
Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
Addis
Daniele
D
Das
Shoubhik
S
Junge
Kathrin
K
Beller
Matthias
M
D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003681:Dehydration; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry
D000577:Amides; D009570:Nitriles; D009942:Organometallic Compounds; D012821:Silanes; D007501:Iron