title: Design, synthesis and analgesic properties of novel conformationally-restricted N-acylhydrazones (NAH).
abstract: A set of six azaheterocycles were designed as conformationally-constrained N-acylhydrazones and tested as analgesics.
authors: Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, Brazil.
authors: Arthur E
authors: AE
authors: Kümmerle
authors: Marina M
authors: MM
authors: Vieira
authors: Martine
authors: M
authors: Schmitt
authors: Ana L P
authors: AL
authors: Miranda
authors: Carlos A M
authors: CA
authors: Fraga
authors: Jean-Jacques
authors: JJ
authors: Bourguignon
authors: Eliezer J
authors: EJ
authors: Barreiro
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D015195:Drug Design; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D051379:Mice; D008968:Molecular Conformation; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D000700:Analgesics; D006835:Hydrazones