In vitro activities of panduratin A against clinical Staphylococcus strains.
In vitro antistaphylococcal activities of panduratin A, a natural chalcone compound isolated from Kaempferia pandurata Roxb, were compared to those of commonly used antimicrobials against clinical staphylococcal isolates. Panduratin A had a MIC at which 90% of bacteria were inhibited of 1 microg/ml for clinical staphylococcal isolates and generally was more potent than commonly used antimicrobials.
Rukayadi
Yaya
Y
Department of Biotechnology, Yonsei University, Seoul 120-749, South Korea.
Lee
Kwanghyung
K
Han
Sunghwa
S
Yong
Dongeun
D
Hwang
Jae-Kwan
JK
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D047188:Chalcones / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013210:Staphylococcus / Q000187:drug effects*; D030521:Zingiberaceae / Q000378:metabolism
D000900:Anti-Bacterial Agents; D047188:Chalcones; C482884:panduratin A