Mastocytosis.
Mastocytosis is characterized by pathologic accumulation and activation of mast cells in tissues and organs. Although the classification for mastocytosis and diagnostic criteria are well accepted, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and responses to treatment. The objective of this article was to make an extensive literature review, providing comprehensive knowledge about the etiopathological and pathophysiological mechanisms, with a special emphasis on diagnosis, classification and treatment of mastocytosis, promoting continued medical education.
Maluf
Luciana Cirillo
LC
Mestre em Ciências da Saúde pela Faculdade de Medicina do ABC, Preceptor da disciplina de Dermatologia da Faculdade de Medicina do ABC, Santo André (SP), Brazil. lcmaluf@hotmail.com
Barros
Jefferson Alfredo de
JA
Machado Filho
Carlos D Aparecida Dos Santos
CD
D006801:Humans; D008415:Mastocytosis / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000473:pathology