Adult muscle stem cells avoid death and Paxes.
In a recent Nature publication, Lepper et al. (2009) use cell-specific lineage tracing and temporally controllable gene deletion approaches to study muscle stem cell function and reveal age-dependent requirements for Pax gene expression.
Brack
Andrew
A
Center of Regenerative Medicine, Massachusetts General Hospital, MGH Charles River Plaza North, Room 4232, Boston, MA 02114-2790, USA. brack.andrew@mgh.harvard.edu
D053687:Adult Stem Cells / Q000378:metabolism*; D000818:Animals; D051379:Mice; D018482:Muscle, Skeletal / Q000378:metabolism*; D051763:PAX7 Transcription Factor / Q000378:metabolism*; D032496:Satellite Cells, Skeletal Muscle / Q000378:metabolism*
D051763:PAX7 Transcription Factor; C497322:Pax7 protein, mouse