Pediatric monomelic amyotrophy: evidence for poliomyelitis in vulnerable populations.
Pediatric monomelic amyotrophy may present a diagnostic challenge. This is particularly true for immigrant or adopted children who have little or no available medical history. We present clinical and electrophysiological data from 11 children with monomelic amyotrophy who had electrophysiological evidence of a unilateral or profoundly asymmetric motor neuronopathy. The cause of amyotrophy in each case is most consistent with prior: (1) wildtype poliovirus myelitis; (2) "polio-like" virus myelitis, or (3) vaccine associated paralytic poliomyelitis.
McMillan
Hugh J
HJ
Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.
Darras
Basil T
BT
Kang
Peter B
PB
Saleh
Firas
F
Jones
H Royden
HR
D000293:Adolescent; D020968:Brachial Plexus Neuritis / Q000175:diagnosis* / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011051:Poliomyelitis / Q000150:complications* / Q000175:diagnosis*; D011153:Population; D011446:Prospective Studies