title: Epidemiological study of paracoccidioidomycosis and histoplasmosis in a suburb of San Félix city, Bolívar state, Venezuela.
abstract: Epidemiologic studies of deep mycosis have been scarce in Bolivar state, where paracoccidioidomycosis and histoplasmosis are considered as endemic diseases. The aim of this study was to determine paracoccidioidomycosis and histoplasmosis prevalences in people from a suburb of San Féix, Bolívar state, Venezuela. Three-hundred volunteers agreed to participate in this study and they were inoculated with paracoccidioidine and histoplasmine. Identification and epidemiologic data were registered. Reading of skin tests after 24 hours was performed in 275 persons. Paracoccidioidine test was positive in 10.2% (n=28). A higher percentage of positive reactions in the age group of 40-50 years old (n=10; 35.7%) was observed. Bricklayers, farmers and miners were positive in 27.3% (3 out of 11), a higher percentage than in people with other occupations. Histoplasmine test was positive in 7.6% of cases (n=21). The higher percentage of reactivity was observed in the age group of 40-50 years old (n=9; 42.9%). There was a direct proportional relationship between staying time in the locality and H. capsulatum infection mainly in persons staying in the area for more than 30 years (p < 0.05). These results showed low prevalences of P. brasiliensis and H. capsulatum infection in this area.
authors: Escola de Ciencias de la Salud Dr. Francisco Battistini Casalta, Universidad de Oriente Núicleo Bolívar, Ciudad Bolívar , Venezuela. jcerme@cantv.net
authors: Julman
authors: J
authors: Cermeño
authors: Julmery
authors: J
authors: Cermeño
authors: Gerardo
authors: G
authors: Godoy
authors: Isabel
authors: I
authors: Hernández
authors: Yida
authors: Y
authors: Orellán
authors: Ytalia
authors: Y
authors: Blanco
authors: Salvador
authors: S
authors: Penna
authors: Luily
authors: L
authors: García
authors: Thamara
authors: T
authors: Mender
authors: Marisa
authors: M
authors: Gonsálvez
authors: César
authors: C
authors: López
authors: Neudys
authors: N
authors: Hernández
authors: Isabel
authors: I
authors: Longa
authors: Esther
authors: E
authors: Gottberg
authors: Amarilys
authors: A
authors: Basanta
authors: Milagros
authors: M
authors: Castro
authors: Iraida
authors: I
authors: Millán
authors: Walesca
authors: W
authors: León
authors: Flor
authors: F
authors: Plaz
authors: Caroline
authors: C
authors: Jahouhari
authors: Ismery
authors: I
authors: Cabello
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005656:Fungal Proteins; D006659:Histoplasmin; D006660:Histoplasmosis / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D010229:Paracoccidioidomycosis / Q000453:epidemiology*; D015995:Prevalence; D012907:Smoking / Q000453:epidemiology; D013383:Suburban Population / Q000706:statistics & numerical data; D014687:Venezuela / Q000453:epidemiology
chemical_list: D005656:Fungal Proteins; C008765:paracoccidioidin; D006659:Histoplasmin