Enantioselective gas chromatographic separation of racemic N-alkylated barbiturates: application of C11-Chirasil-Dex as chiral stationary phase in GC.
Chirasil-beta-Dex containing an undecamethylene spacer (C11-Chirasil-Dex) was synthesized and used as chiral stationary phase (CSP) in enantioselective gas chromatography (GC). The versatility of the new stationary phase in the simultaneous enantiomeric separation of a set of N-alkylated barbiturates is demonstrated.
Ghanem
Ashraf
A
Biomedicinal Chemistry Unit, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, (MBC-03-95), P.O. Box 3354, Riyadh 11211, Saudi Arabia. ghanem@kfshrc.edu.sa