Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model.
Lynch
Henry T
HT
Department of Preventive Medicine and Public Health, Creighton University School of Medicine, Omaha, NE 68178, USA. htlynch@creighton.edu
Lynch
Jane F
JF
Attard
Thomas A
TA
D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D045647:DNA Glycosylases / Q000235:genetics; D019468:Disease Management; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D018095:Germ-Line Mutation; D006801:Humans; D000070957:MutL Protein Homolog 1; D000070956:MutL Proteins; D009363:Neoplasm Proteins / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics; D010375:Pedigree; D017410:Practice Guidelines as Topic; D012017:Referral and Consultation
D048868:Adaptor Proteins, Signal Transducing; C501486:MLH1 protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; C088996:PMS1 protein, human; D045647:DNA Glycosylases; C061738:mutY adenine glycosylase; D000070957:MutL Protein Homolog 1; D000070956:MutL Proteins