title: The scientific basis of migraine.
abstract: Through genetic studies and neuroimaging techniques, our knowledge of the scientific basis of migraine continues to grow. The assumption that migraine is an inherited disorder has gained considerable support from studies of twins and of patients with familial hemiplegic migraine, in whom specific gene defects have been identified. Neuroimaging techniques, such as perfusion-weighted imaging, diffusion-weighted imaging, and blood oxygen level-dependent imaging, have allowed the visualization of changes in the brain that occur during the aura. Such information should help in the effective management and possible prevention of migraine attacks.
authors: Consultants in Neurology, Ltd., Northbrook, IL 60062, USA. dwynnmd@interaccess.com
authors: D R
authors: DR
authors: Wynn
mesh_terms: D013181:Cortical Spreading Depression; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D018810:Magnetic Resonance Angiography; D008881:Migraine Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D012307:Risk Factors; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D014363:Tryptamines / Q000627:therapeutic use
chemical_list: D017366:Serotonin Receptor Agonists; D014363:Tryptamines