title: [Application of self-assembling peptide nanofiber scaffold in nerve tissue engineering].
abstract: OBJECTIVE
  To review the fundamental research and the experimental study in the nerve tissue engineering of self-assembling peptide nanofiber scaffold (SAPNS).
  
  
  METHODS
  The literature concerning basic and experimental studies on SAPNS in the nerve tissue engineering was extensively reviewed.
  
  
  RESULTS
  SAPNS can promote the neural stem cell adhesion, proliferation, differentiation and neuron axon outward growth and extension, promote extracellular matrix synthesis and inhibit glial cell adhesion and differentiation, and simulate the environment of a cell in the body.
  
  
  CONCLUSIONS
  SAPNS is an ideal matrix material and provides a new way for the repair of nerve tissue injury.
authors: Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan Hubei, 430027, P.R. China.
authors: Baichuan
authors: B
authors: Wang
authors: Zengwu
authors: Z
authors: Shao
mesh_terms: D001672:Biocompatible Materials; D057139:Nanofibers; D009416:Nerve Regeneration; D010455:Peptides; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials; D010455:Peptides