Lewis acid promoted carbon-carbon double-bond formation via organozinc reagents and carbonyl compounds.
Using cheap and readily available AlCl(3) as Lewis acid, functionalized aldehydes react with organozinc reagents to give (E)-alkenes stereoselectively in high yields.
Peng
Zhi-Yong
ZY
School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Ma
Fang-Fang
FF
Zhu
Lv-Feng
LF
Xie
Xiao-Min
XM
Zhang
Zhaoguo
Z
D000143:Acids / Q000737:chemistry*; D000438:Alcohols / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry; D001965:Bromides / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D004987:Ethers / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D008956:Models, Chemical; D013237:Stereoisomerism; D014050:Toluene / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
D000143:Acids; D000438:Alcohols; D000447:Aldehydes; D001965:Bromides; D004987:Ethers; D007659:Ketones; D008670:Metals; D014050:Toluene; D002244:Carbon; D008094:Lithium; D008274:Magnesium; D015032:Zinc