title: Flow velocity estimation by complex ambiguity free joint Spectral and Time domain Optical Coherence Tomography.
abstract: We show that recently introduced joint Spectral and Time domain Optical Coherence Tomography (STdOCT) can be used for simultaneous complex ambiguity removal and functional Spectral OCT images. This permits to take advantage of higher sensitivity achievable near the zero-path delay. The technique can be used with all Spectral OCT systems that are equipped with an optical delay line (ODL) and provide oversampled scanning patterns. High sensitivity provided by STdOCT allows this technique to be used in Spectral OCT setups with acquisition speed of 100,000 lines/s. We show that different imaging ranges and velocity ranges can be achieved by switching on/off the ODL and a small modification in the processing algorithm. Additionally, the relatively small computational burden of the technique allows for fast computations in the range of less than 5 minutes for 3D data set. We present application of proposed technique to full-range two- and three-dimensional imaging. Morphological and Doppler tomograms of human retina in-vivo are shown. Finally, we identify and discuss artifacts of the technique.
authors: Institute of Physics, Nicolaus Copernicus University, PL-87-100 Toruń, Poland.
authors: Maciej
authors: M
authors: Szkulmowski
authors: Ireneusz
authors: I
authors: Grulkowski
authors: Daniel
authors: D
authors: Szlag
authors: Anna
authors: A
authors: Szkulmowska
authors: Andrzej
authors: A
authors: Kowalczyk
authors: Maciej
authors: M
authors: Wojtkowski
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000379:methods*; D001783:Blood Flow Velocity / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D012171:Retinal Vessels / Q000166:cytology* / Q000502:physiology*; D041623:Tomography, Optical Coherence / Q000379:methods*