[Temporal evolution of breast cancer stages in a population-based cancer registry in the Brazilian central region].
OBJECTIVE
To analyze the temporal changes of breast cancer staging at diagnosis among women living in Goiânia, Goiás, Brazil, between 1989 and 2003.


METHODS
Retrospective and descriptive study in which the cases were identified from the Population-Based Cancer Registry of Goiânia for the period from 1989 to 2003. The variables studied were age, diagnostic method, topographic sublocation, morphology and breast cancer staging. Frequency analyses were carried out on the variables and means, and the medians for the age were determined. The SPSS(R) 15.0 software was used for statistical analyses.


RESULTS
A total of 3,204 breast cancer cases were collected. The mean age was 56 years (sd+/-16 years). With regard to clinical staging, 45.6% of the cases were found to be localized in the breast, with an increased rate of 19.25% between the first and the third five-year period (p<0.001; CI 95%=0.14-0.23) and 10.2% of cases were with distant metastases. However, a reduction of 17.74% for metastatic cases in the same interval (p<0.001 e CI 95%=0.14-21) was observed. The in situ case rate was 0.2% in 1989-1993 and increased to 6.2% in 1999-2003 (p<0.001, IC95%=4.9-7.4).


CONCLUSIONS
The diagnostic profile of breast cancer in the city of Goiânia is changing. Substantial increases in the number of early breast cancer cases are being found in relation to the number of advanced cases.
Martins
Edesio
E
Registro de Câncer de Base Populacional de Goiânia, Associação de Combate ao Câncer em Goiás, Goiânia, GO, Brasil.
Freitas-Junior
Ruffo
R
Curado
Maria Paula
MP
Freitas
Nilceana Maya Aires
NM
De Oliveira
José Carlos
JC
Silva
Carleane Maciel Bandeira E
CM
D000328:Adult; D001938:Brazil; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D012042:Registries; D012189:Retrospective Studies; D013997:Time Factors