Bifunctional bisphosphonate complexes for the diagnosis and therapy of bone metastases.
Easily synthesised and structurally well-defined novel imaging/therapeutic radiopharmaceutical agents for bone metastases are described.
Torres Martin de Rosales
R
R
Division of Imaging Sciences, The Rayne Institute, King's College London, 4th Floor Lambeth Wing, St. Thomas Hospital, London, UK SE1 7EH.
Finucane
C
C
Mather
S J
SJ
Blower
P J
PJ
D000818:Animals; D001859:Bone Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D004164:Diphosphonates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008807:Mice, Inbred BALB C; D015394:Molecular Structure; D015609:Organotechnetium Compounds / Q000737:chemistry* / Q000627:therapeutic use; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D012211:Rhenium / Q000737:chemistry*
D004164:Diphosphonates; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C109881:dithio-bisphosphine tc99m; D012211:Rhenium