Detection of artemisinin-resistant Plasmodium falciparum in malarial infection: a brief review of methods.
The WHO has recommended artemisinin-based combination therapy (ACT) for the treatment of malaria in disease endemic countries. In an attempt to assess the sensitivity of Plasmodium falciparum to the drug, various methods have been used. It is the purpose of this short review to critically examine these methods and give recommendations.
Quashie
Neils B
NB
Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Glasgow Biomedical Research Centre, University of Glasgow, 120 University Place, Glasgow G12 8TA, UK. N.Quashie@bio.gla.ac.uk
D000890:Anti-Infective Agents / Q000494:pharmacology*; D037621:Artemisinins / Q000494:pharmacology*; D004351:Drug Resistance / Q000235:genetics*; D004359:Drug Therapy, Combination; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000469:parasitology; D021261:Parasitic Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics; D017354:Point Mutation / Q000235:genetics
D000890:Anti-Infective Agents; D037621:Artemisinins; C031327:artemisinin