Prognosis of idiopathic downbeat nystagmus.
Downbeat nystagmus (DBN) is a common form of acquired involuntary ocular oscillation overriding fixation. Little is known about the natural evolution of DBN in idiopathic cases. Therefore, eye movements were recorded in seven patients with idiopathic DBN by search-coil technique over a course of up to six years. Neither the slow-phase velocity (SPV) nor the dependency of the SPV on gaze position as an indicator of dysfunction of the oculomotor velocity-to-position integrator changed significantly over the time course investigated in this study.
Wagner
Judith
J
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany. judith.wagner@med.uni-muenchen.de
Lehnen
Nadine
N
Glasauer
Stefan
S
Strupp
Michael
M
Brandt
Thomas
T
D000368:Aged; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000503:physiopathology*; D011379:Prognosis