Acquired ichthyosis as a paraneoplastic syndrome in Hodgkin's disease.
An 80-year-old man was admitted to hospital with low-grade fever, weight loss, asthenia and anorexia. Physical examination revealed generalised ichthyosis with palmoplantar hyperkeratosis. CT scan showed retroperitoneal and inguinal lymph node enlargement. An inguinal lymph node biopsy revealed Hodgkin's disease (nodular-sclerosing subtype). The patient received chemotherapy, showing a clear improvement of both skin lesions and lymph nodes.
Riesco Martínez
María Carmen
MC
Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón Madrid, Spain.
Muñoz Martín
Andrés J
AJ
Zamberk Majlis
Pamela
P
Adeva Alfonso
Jorge
J
Sabin Domínguez
Pilar
P
García Alfonso
Pilar
P
Pérez Fernández
Ricardo
R
D000369:Aged, 80 and over; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000473:pathology