title: Multidetector CTA in the quantification of internal carotid artery stenosis: value of different reformation techniques and axial source images compared with selective carotid arteriography.
abstract: OBJECTIVE
  To evaluate the role of 4 different reformation techniques and axial images from multidetector computed tomographic angiography (MDCTA) versus selective carotid arteriography (SCA) in patients with internal carotid artery (ICA) stenosis.
  
  
  METHODS
  Imaging studies from 50 patients (43 men; mean age 70.3+/-8.0 years, range 51-85) with known cerebrovascular disease who underwent MDCTA and SCA in a single university hospital were retrospectively analyzed. Axial images, multiplanar reformation (MPR), curved planar reformation (CPR), volume rendering threshold (VRT), and virtual angioscopy (VA) images were reviewed by 2 independent observers who were blinded to the results of SCA, which served as the gold standard. The degree of stenosis was categorized as 0%-49%, 50%-69%, or 70%-99%; a stenosis >70% was considered as hemodynamically significant.
  
  
  RESULTS
  Thirty-four hemodynamically significant stenoses were identified on SCA. The agreement with SCA images was good for both observers using axial CT images (kappa = 0.89 for observer 1 and 0.88 for observer 2); corresponding results for MPR and CPR were kappa = 0.91 and 0.92 for observer 1 and 0.88 and 0.91 for observer 2, respectively. VRT (kappa = 0.72 for observer 1 and 0.66 for observer 2) and VA (kappa = 0.74 for observer 1 and 0.70 for observer 2) showed a slightly inferior correlation with SCA images. Sensitivities for reformations and axial CT images were 100% each; corresponding specificities ranged from 85% to 95%.
  
  
  CONCLUSIONS
  Axial images as well as all 4 reformation techniques agreed well with SCA in the grading of ICA stenosis.
authors: Department of Radiology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria. stefan.puchner@meduniwien.ac.at
authors: Stefan
authors: S
authors: Puchner
authors: Martin
authors: M
authors: Popovic
authors: Florian
authors: F
authors: Wolf
authors: Markus
authors: M
authors: Reiter
authors: Johannes
authors: J
authors: Lammer
authors: Robert A
authors: RA
authors: Bucek
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D017546:Angioscopy; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed