title: Post-cardiac injury syndrome following transvenous pacemaker insertion: A case report and review of the literature.
abstract: Post-cardiac injury syndrome is an inflammatory process involving the pleura and pericardium secondary to cardiac injury and can develop following transvenous pacemaker insertion. We now report a patient who developed this syndrome following dual-chamber pacemaker insertion with active fixation of the atrial and ventricular leads. The pericardial fluid was bloody and had a neutrophilic predominance. The pericardial biopsy revealed fibrinous pericarditis with a mixed inflammatory cell infiltrate. The pleural effusion was exudative and had a neutrophilic predominance. Nine similar cases were identified in the English literature dating back to 1975. These patients usually present within one month after pacemaker insertion. They have exudative pericardial and pleural effusions. The pericardial effusions can cause tamponade and may require treatment with either catheter drainage or a surgical window. Some of these patients respond well to anti-inflammatory medications, including prednisone. Therefore, early identification of these patients could allow medical treatment and might help avoid the need for a surgical procedure. Cardiologists should remember that this uncommon syndrome can occur after routine endovascular procedures.
authors: Department of Internal Medicine, Texas Tech University Health Sciences Center School of Medicine, Lubbock, 79430, United States. cihan.cevik@ttuhsc.edu
authors: Cihan
authors: C
authors: Cevik
authors: Troy
authors: T
authors: Wilborn
authors: Rita
authors: R
authors: Corona
authors: Elizabeth
authors: E
authors: Schanzmeyer
authors: Kenneth
authors: K
authors: Nugent
mesh_terms: D000368:Aged; D001241:Aspirin / Q000627:therapeutic use; D006335:Heart Injuries / Q000209:etiology*; D006801:Humans; D007049:Iatrogenic Disease; D007249:Inflammation / Q000209:etiology*; D008297:Male; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D010493:Pericarditis / Q000209:etiology*; D010496:Pericardium / Q000293:injuries; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010994:Pleura / Q000293:injuries; D010996:Pleural Effusion / Q000209:etiology*; D013577:Syndrome; D013997:Time Factors
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin