Prevalence and determinants of diabetes and impaired fasting glucose among urban community-dwelling adults in Guangzhou, China.
OBJECTIVE
This study aimed to estimate the prevalence of diabetes and impaired fasting glucose (IFG) in the adult population aged >or= 20 years in Guangzhou and to evaluate the associated risk factors.


METHODS
A total of 6197 randomly selected adults, aged >or= 20 years and living for at least 5 years in Guangzhou, participated in questionnaire-based interviews between 2006 and 2007, and had their clinical characteristics and standard blood chemistries measured. A 75 g OGTT was conducted for those subjects with fasting glucose levels >or= 5.6 mmol/L. Diabetes and IFG were defined according to WHO 1999 criteria.


RESULTS
Based on Chinese census data, the age- and gender-standardized prevalences of diabetes and IFG were 5.5% and 3.3%, respectively. Among the identified diabetic individuals in the present investigation, 42.3% were newly diagnosed. The prevalence of diabetes and IFG increased with age. The results of multivariate logistic-regression analyses showed that diabetes and IFG were significantly associated with age, a family history of diabetes, obesity, hypertension and hyperlipidaemia.


CONCLUSIONS
The prevalences of diabetes and IFG have increased dramatically over the past decade. Yet, a large proportion of cases go undiagnosed. These results suggest an urgent need to establish regular population-based diabetes screening in Guangzhou.
Wang
H
H
Department of Biostatistics and Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Qiu
Q
Q
Tan
L-L
LL
Liu
T
T
Deng
X-Q
XQ
Chen
Y-M
YM
Chen
W
W
Yu
X-Q
XQ
Hu
B-J
BJ
Chen
W-Q
WQ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D002681:China / Q000453:epidemiology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D020022:Genetic Predisposition to Disease; D018149:Glucose Intolerance / Q000453:epidemiology*; D006306:Health Surveys; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000453:epidemiology; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D050177:Overweight / Q000150:complications / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D014505:Urban Population; D055815:Young Adult