title: Generalized Sweet syndrome lesions associated with Behçet disease: a true association or simply co-morbidity?
abstract: Sweet syndrome or acute febrile neutrophilic dermatosis is a condition characterized by painful erythematous papules, nodules, and plaques, which demonstrate mature neutrophilic infiltration of the upper dermis histopathologically, and is usually associated with systemic symptoms such as fever and neutrophilia. Generalized Sweet syndrome lesions are usually noted in association with malignancies. Sweet syndrome lesions are rarely seen in patients with Behçet disease and, if present, are usually fewer in number. In this report, we present two female patients who developed generalized Sweet syndrome lesions during follow-up after the diagnosis of Behçet disease. The clinical and histopathologic findings in our patients together with the data in the literature suggest that generalized Sweet syndrome lesions in a patient with clinically inactive Behçet disease should remind the clinician that a strict differential diagnosis needs to be made between Sweet syndrome associated with Behçet disease and the rare cutaneous manifestation of Behçet disease that resembles the lesions of Sweet syndrome.
authors: Eşrefpaşa Hospital, Department of Dermatology, Izmir, Turkey. gafkaradogan@yahoo.com
authors: Serap Köran
authors: SK
authors: Karadoğan
authors: Emel Bülbül
authors: EB
authors: Başkan
authors: Gülçin
authors: G
authors: Alkan
authors: Hayriye
authors: H
authors: Saricaoğlu
authors: Sükran
authors: S
authors: Tunali
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016463:Sweet Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology