title: Unconventional oxazole formation from isocyanides.
abstract: The coupling of an acyl chloride with an isocyanide affords 2,5-disubstituted oxazoles under mild basic conditions instead of 4,5-disubstituted derivatives when using Schöllkopf conditions (butyllithium); this reaction constitutes a remarkable example of a base-induced chemoselective process in isocyanide chemistry.
authors: Laboratoire Chimie et Procédés, UMR 7652, Ecole Nationale Supérieure des Techniques Avancées, 32 Bd Victor, 75015, Paris, France.
authors: Aurélie
authors: A
authors: dos Santos
authors: Laurent
authors: L
authors: El Kaïm
authors: Laurence
authors: L
authors: Grimaud
authors: Caroline
authors: C
authors: Ronsseray
mesh_terms: D003486:Cyanides / Q000378:metabolism*; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*
chemical_list: D003486:Cyanides; D010080:Oxazoles