Successful treatment of ulcerous skin lesion caused by mistaken intradermal injection of BCG (Bacille de Calmette et Guerin) vaccine with anti-tuberculous drugs and systemic administration of corticosteroid.
"Tokyo 172" BCG vaccine designed for percutaneous inoculation is widely used in Japan. This vaccine is a much higher concentration of M. bovis BCG than that of the BCG vaccine designed for intradermal inoculation widely used in other countries. A patient who suffered from an ulcerous skin lesion as a result of the intradermal injection of "Tokyo 172" BCG vaccine accidentally was referred to our hospital. Systemic corticosteroid was administered with anti-tuberculous drugs, achieving a complete improvement of the skin lesion.
Watanabe
Koji
K
AIDS Clinical Center, International Medical Center of Japan, Tokyo. kwatanab@imcj.acc.go.jp
Teruya
Katsuji
K
Kikuchi
Yoshimi
Y
Oka
Shinichi
S
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007271:Injections, Intradermal; D008508:Medication Errors; D011239:Prednisolone / Q000627:therapeutic use; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D014374:Tuberculin Test / Q000009:adverse effects; D055815:Young Adult
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D001500:BCG Vaccine; D011239:Prednisolone