Modulation of Th1/Th2 balance by infliximab rescues postoperative occurrence of small-intestinal inflammation associated with ulcerative colitis.
Akitake
Reiko
R
Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan.
Nakase
Hiroshi
H
Tamaoki
Masashi
M
Ueno
Satoru
S
Mikami
Sakae
S
Chiba
Tsutomu
T
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001706:Biopsy; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D039021:Colonic Pouches / Q000009:adverse effects; D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D004382:Duodenitis / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D004386:Duodenum / Q000187:drug effects* / Q000276:immunology; D016145:Endoscopy, Digestive System; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects; D000069285:Infliximab; D019449:Pouchitis / Q000188:drug therapy / Q000276:immunology; D016737:Proctocolectomy, Restorative / Q000009:adverse effects; D012008:Recurrence; D018417:Th1 Cells / Q000187:drug effects* / Q000276:immunology; D018418:Th2 Cells / Q000187:drug effects* / Q000276:immunology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D000069285:Infliximab