title: Decline in the nationwide trends in in-hospital mortality of patients undergoing multivessel percutaneous coronary intervention.
abstract: BACKGROUND
  Advances in the safety of percutaneous coronary interventions have been significant in recent years. The goal of this study was to evaluate any decline in the age-adjusted in-hospital mortality rate in patients undergoing multivessel percutaneous coronary intervention (MVPCI) using a very large database from 1988 to 2004 in the United States.
  
  
  METHODS
  The Nationwide Inpatient Sample (NIS) database was utilized to calculate the age-adjusted mortality rate for MVPCI from 1988 to 2004 in patients over the age of 40 years retrospectively. Specific ICD-9-CM codes for MVPCI were used for this study. Patient demographic data were also analyzed and adjusted for age from the database.
  
  
  RESULTS
  The mean age was 71.56 +/- 10.59 years (53.55% male). From 1988 the age-adjusted mortality rate was stable until 1999, with a steady decline to the lowest level in 2004. In 1988, the rate was 67.42 (95% CI = 181-316.14), in 1999 51.02 (95% CI = 27-129.32), and in 2004, 40.06 (95% CI 5.6-85.83) per 100,000. Total death also declined from 1.77% to 1.25%. This trend was similar across gender and ethnicities.
  
  
  CONCLUSIONS
  The age-adjusted mortality from MVPCI was steady until 1999, but declined to the lowest level in 2004. This trend most likely reflects advancements in the care of patients undergoing high-risk coronary interventions.
authors: Associate Professor of Medicine, The Southern Arizona VA Health Care System and University of Arizona Sarver Heart Center, 1501 North Campbell Avenue, Tucson, AZ, 85724, USA. rmova@aol.com
authors: Mohammad Reza
authors: MR
authors: Movahed
authors: Radhakrishnan
authors: R
authors: Ramaraj
authors: M Mazen
authors: MM
authors: Jamal
authors: Mehrtash
authors: M
authors: Hashemzadeh
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation / Q000379:methods / Q000401:mortality*; D003324:Coronary Artery Disease / Q000628:therapy; D054855:Drug-Eluting Stents; D005260:Female; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014481:United States