title: Steroid pulse therapy for protein-losing enteropathy after the Fontan operation.
abstract: A 19-year-old male with Fontan circulation developed protein-losing enteropathy associated with acute enteritis. Although his central venous pressure was in the normal range, subcutaneous high molecular heparin injection and oral predonisolone administration were not effective. We initiated intravenous high-dose methyl-predonisolone (15 mg/kg/day) for 3 days followed by oral predonisolone (0.5 mg/kg/day) for 4 days and repeated the course in 2 weeks. The serum protein and albumin increased to the normal level at 2 months after pulse therapy. The patient has not shown any recurrence of such protein-losing enteropathy for 2 years without any steroid agents.
authors: Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2(E1), Yamadaoka, Suita, Osaka, Japan.
authors: Takaya
authors: T
authors: Hoashi
authors: Hajime
authors: H
authors: Ichikawa
authors: Takayoshi
authors: T
authors: Ueno
authors: Shigetoyo
authors: S
authors: Kogaki
authors: Yoshiki
authors: Y
authors: Sawa
mesh_terms: D000284:Administration, Oral; D018729:Fontan Procedure; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy*; D011504:Protein-Losing Enteropathies / Q000000981:diagnostic imaging / Q000188:drug therapy*; D020551:Pulse Therapy, Drug; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D013668:Technetium Tc 99m Aggregated Albumin; D008775:Methylprednisolone