Rheological behavior, zeta potential, and accelerated stability tests of Buriti oil (Mauritia flexuosa) emulsions containing lyotropic liquid crystals.
BACKGROUND
It is well known that the Amazon region presents a huge biodiversity; therefore, countless natural resources are being employed in the production of phytocosmetics and phytomedicines.


OBJECTIVE
The purpose of this work was to obtain emulsions produced with Buriti oil and non-ionic surfactants.


METHODS
Two surfactant systems were employed (Steareth-2 associated to Ceteareth-5 and to Ceteareth-20) to produce the emulsions using phase diagram method. Emulsions were obtained by echo-planar imaging method at 75°C. Rheological behavior and zeta potential were evaluated, and accelerated stability tests were performed.


RESULTS
All emulsions analyzed presented pseudoplastic behavior. Zeta potential values were obtained between -14.2 and -53.3 mV. The formulations did not show changes in either physical stability, pH, or rheological behavior after accelerated stability tests. Significant differences were observed only after temperature cycling test.


CONCLUSIONS
Based on these results, the emulsions obtained could be considered as promising delivery systems.
Zanatta
Cinthia Fernanda
CF
Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, São Paulo, Brazil. cinthiafz@yahoo.com.br
de Faria Sato
Anne Miwa Callejón
AM
de Camargo
Flavio Bueno
FB
Campos
Patrícia Maria Berardo Gonçalves Maia
PM
Rocha-Filho
Pedro Alves
PA
D002338:Carotenoids / Q000008:administration & dosage* / Q000737:chemistry; D016503:Drug Delivery Systems; D004355:Drug Stability; D004356:Drug Storage; D004655:Emulsions; D006863:Hydrogen-Ion Concentration; D050866:Liquid Crystals / Q000737:chemistry; D010938:Plant Oils / Q000008:administration & dosage* / Q000737:chemistry; D012212:Rheology; D013501:Surface-Active Agents / Q000737:chemistry*; D013696:Temperature
D004655:Emulsions; D010938:Plant Oils; D013501:Surface-Active Agents; C548591:buriti oil; D002338:Carotenoids