title: Emergence of oseltamivir-resistant influenza A H1N1 virus during the 2007-2008 winter season in Luxembourg: clinical characteristics and epidemiology.
abstract: Human cases of oseltamivir-resistant influenza A H1N1 virus emerging in 2007-2008 in Luxembourg were not associated with treatment, prophylaxis or stockpiling of oseltamivir. Following initial local seeding, oseltamivir-resistant strains spread synchronously to sensitive strains causing a similar epidemiology and clinical symptoms.
authors: Microbiology, National Health Laboratory, PO Box 1102, L-1011 Luxembourg, Luxembourg. joel.mossong@lns.etat.lu
authors: Joël
authors: J
authors: Mossong
authors: Matthias
authors: M
authors: Opp
authors: Nancy
authors: N
authors: Gerloff
authors: Patrick
authors: P
authors: Hau
authors: Jacques
authors: J
authors: Kremer
authors: Angie
authors: A
authors: Lackenby
authors: Vicki
authors: V
authors: Gregory
authors: Jos
authors: J
authors: Even
authors: Pierrette
authors: P
authors: Huberty-Krau
authors: Claude P
authors: CP
authors: Muller
authors: François
authors: F
authors: Schneider
mesh_terms: D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D024882:Drug Resistance, Viral; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification* / Q000502:physiology; D007251:Influenza, Human / Q000188:drug therapy / Q000453:epidemiology* / Q000821:virology; D008189:Luxembourg / Q000453:epidemiology; D008297:Male; D008969:Molecular Sequence Data; D053139:Oseltamivir / Q000627:therapeutic use*; D010802:Phylogeny; D012621:Seasons; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir