[Hypertension and renal disease].
Renal mechanisms, in particular the renin-angiotensin system and renal salt handling, are of major importance in blood pressure regulation. Co-existence of hypertension and decreased renal function may be due to nephrosclerosis secondary to hypertension, or primary renal disease with secondary hypertension. Mild degrees of chronic kidney disease (CKD) can be detected in around 10% of the population, and detection is important as CKD is an important risk factor for atherosclerotic cardiovascular disease. Conversely, heart failure may cause an impairment of renal function. In chronic progressive nephropathy, effective blood pressure lowering is of paramount importance, and angiotensin converting enzyme inhibitors and angiotensin receptor blockers are agents of choice.
Kamper
Anne-Lise
AL
Rigshospitalet, Nefrologisk Afdeling.
Pedersen
Erling B
EB
Strandgaard
Svend
S
D000959:Antihypertensive Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000209:etiology; D018450:Disease Progression; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D007674:Kidney Diseases / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D009400:Nephrosclerosis / Q000150:complications / Q000175:diagnosis / Q000209:etiology; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis / Q000209:etiology; D012307:Risk Factors
D000959:Antihypertensive Agents