[Evaluation of the rate of lipid peroxidation and antioxidant defense in blood during gynecological laparoscopic operations].
The impact of gynecological operations on the rate of lipid peroxidation (LPO) and erythrocytic antioxidant defense (EAOD) was studied in women with uterine myoma. The higher rate of LPO and the decreased level of vitamin E were preoperatively found. A further increase in LPO activity and a reduction in vitamin E concentrations were observed 1-4 days after surgery. Recovery of the study parameters was seen on days 5-7 postoperatively. The enzyme glutathione-S-transferase was ascertained to play a pivotal role in the EAOD system.
Poliakova
V A
VA
Vinokurova
E A
EA
Suplotov
S N
SN
Zhuravleva
T D
TD
Karpova
I A
IA
Iaskevich
N N
NN
Malkhazova
M T
MT
Karmatskikh
T N
TN
D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism; D005260:Female; D005982:Glutathione Transferase / Q000097:blood; D006801:Humans; D007044:Hysterectomy; D010535:Laparoscopy; D007889:Leiomyoma / Q000097:blood* / Q000473:pathology / Q000601:surgery; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D013482:Superoxide Dismutase / Q000097:blood; D014594:Uterine Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery; D014599:Uterus / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D014810:Vitamin E / Q000097:blood
D000975:Antioxidants; D014810:Vitamin E; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D005982:Glutathione Transferase