title: Total synthesis and structure revision of the (-)-maduropeptin chromophore.
abstract: The proposed structure of the maduropeptin chromophore, the biologically active component of the highly potent chromoprotein antitumor antibiotics, was stereoselectively synthesized but did not satisfy the spectra of the natural product. We demonstrated that the correct structure is diastereomeric, which possesses an antipodal sugar moiety.
authors: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
authors: Kazuo
authors: K
authors: Komano
authors: Satoshi
authors: S
authors: Shimamura
authors: Yutaro
authors: Y
authors: Norizuki
authors: Donglin
authors: D
authors: Zhao
authors: Chizuko
authors: C
authors: Kabuto
authors: Itaru
authors: I
authors: Sato
authors: Masahiro
authors: M
authors: Hirama
mesh_terms: D053281:Enediynes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D053281:Enediynes; C509891:maduropeptin enediyne