[DNA vaccines and recombinant antigens in prevention of Toxoplasma gondii infections--current status of the studies].
Toxoplasmosis caused by an intracellular parasite Toxoplasma gondii is still one of major medical and veterinary problems and there is still need for a vaccine for human toxoplasmosis. Despite years of research much remains to be done to develop effective vaccine. The article presents the current status of vaccine strategies against toxoplasmosis with focus on the most developed approaches using naked DNA and recombinant antigens.
Hiszczyńska-Sawicka
Elzbieta
E
Katedra Mikrobiologii, Politechnika Gdańska, ul. G. Narutowicza 11/12, 80-952 Gdańsk. ehiszczynska@yahoo.com
Holec-Gasior
Lucyna
L
Kur
Józef
J
D000953:Antigens, Protozoan / Q000008:administration & dosage / Q000276:immunology / Q000378:metabolism; D006801:Humans; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000276:immunology / Q000378:metabolism; D014123:Toxoplasmosis / Q000517:prevention & control*; D019444:Vaccines, DNA / Q000008:administration & dosage* / Q000276:immunology
D000953:Antigens, Protozoan; D011994:Recombinant Proteins; D019444:Vaccines, DNA