title: Osteochondral autografting (mosaicplasty) in articular cartilage defects in the knee: results at 5 to 9 years.
abstract: We evaluated short- and medium-term results of the treatment of articular cartilage defects of the knee with autogenous cylindrical osteochondral grafts (mosaicplasty) in 69 patients (median age 33 years) with symptomatic articular cartilage defects. Data of Lysholm score and visual analogue scale (VAS) of pain (0=no pain; 100=worst possible pain) were collected before the surgery, at 12 months postoperatively and 5 to 9 (median 7) years after the surgery. At the last follow-up the patients were also asked to state their degree of satisfaction with the outcome on a VAS (0=not at all satisfied; 100=completely satisfied), and to answer if they would have undergone the surgery again if necessary (yes or no). The mean Lysholm score and VAS of pain improved from 48 and 62, respectively, at the time of surgery to 81 and 24, respectively, at the 12-months follow-up (p<0.001 for both comparisons). From 12 months postoperatively, the Lysholm score and VAS of pain deteriorated to 68 and 32, respectively at the 5- to 9-year follow-up (p<0.001 and p=0.018, respectively). The mean degree of satisfaction with the outcome was 70 (SD 28), and 61 patients (88%) stated that they would have undergone the surgery again. In conclusion, the mosaicplasty leads to improvement of symptoms and function at short- and medium-term follow-up. A deterioration of the results is observed from 12 months postoperatively to 5-9 years postoperatively.
authors: Deaconess University Hospital, Haraldsplass, NO 5009, Bergen, Norway. eirik.solheim@uib.no
authors: Eirik
authors: E
authors: Solheim
authors: Janne
authors: J
authors: Hegna
authors: Jannike
authors: J
authors: Oyen
authors: Ove Kristian
authors: OK
authors: Austgulen
authors: Thomas
authors: T
authors: Harlem
authors: Torbjørn
authors: T
authors: Strand
mesh_terms: D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation; D002356:Cartilage / Q000637:transplantation; D002357:Cartilage Diseases / Q000473:pathology / Q000601:surgery*; D002358:Cartilage, Articular / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007718:Knee Injuries / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D017060:Patient Satisfaction; D016896:Treatment Outcome; D055815:Young Adult