Infantile fibrosarcoma successfully treated with chemotherapy, with occurrence of calcifying aponeurotic fibroma and pleomorphic/spindled celled lipoma at the site 12 years later.
The treatment of infantile fibrosarcoma has traditionally been wide resection. Chemotherapy has been investigated as an adjuvant and primary treatment in cases in which surgery would cause unacceptable morbidity. Recurrences normally occur within a year of completion of the chemotherapy and display the same histology. We present a child with an infantile fibrosarcoma of the elbow, successfully treated with chemotherapy alone, who developed a calcifying aponeurotic fibroma and a spindle cell/pleomorphic lipoma at the tumor site 12 years later.
DeComas
Amalia M
AM
Department of Orthopaedic Surgery, Ochsner Health System, 1514 Jefferson Highway, New Orleans, LA 70121, USA. adecomas@ochsner.org
Heinrich
Stephen D
SD
Craver
Randall
R
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002114:Calcinosis; D002648:Child; D004550:Elbow / Q000473:pathology; D005260:Female; D005350:Fibroma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005354:Fibrosarcoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000188:drug therapy* / Q000473:pathology
D000970:Antineoplastic Agents