Point mutation rate of bacteriophage PhiX174.
The point mutation rate of phage PhiX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0x10(-6) substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per round of copying in DNA-based microorganisms).
Cuevas
José M
JM
Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departamento de Genética, Universitat de València, 46071 València, Spain.
Duffy
Siobain
S
Sanjuán
Rafael
R
D010584:Bacteriophage phi X 174 / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics; D004926:Escherichia coli / Q000821:virology; D016679:Genome, Viral / Q000235:genetics; D017354:Point Mutation
D004279:DNA, Viral