Current paradigms in treating erectile dysfunction.
In treating erectile dysfunction (ED) effectively, a hierarchy of treatments based on efficacy, safety, and other factors can be a valuable instrument for assisting clinical decisions. First-line therapies, in this hierarchy, include sildenafil--the only orally administered erectogenic drug currently available--vacuum constriction devices, and psychological counseling and sexual therapy. Second-line therapies include intracavernous injection and intraurethral suppositories. Third-line therapies include penile implant surgery. This article presents a broad overview of all available therapies, but concentrates on sildenafil as the current paradigm of broadly efficacious, safe, and convenient treatment for ED.
Padma-Nathan
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University of Southern California School of Medicine, Los Angeles, USA.
D003376:Counseling; D007172:Erectile Dysfunction / Q000628:therapy*; D006801:Humans; D008297:Male; D015917:Penile Prosthesis; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use; D010879:Piperazines / Q000627:therapeutic use; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate