[Conjunctival microbiota and antibiotics resistance in preterm newborns hospitalized in neonatal intensive care unit].
OBJECTIVE
To analyze the conjunctival bacterial flora and the antibiotics resistance pattern in preterm newborns at the Neonatal Intensive Care Unit (NICU), in 'Hospital das Clínicas da Universidade Federal de Pernambuco - UFPE'.


METHODS
Material from the conjunctival sac was obtained from 48 premature infants eyes that stayed at in NICU more than 48 hours.


RESULTS
Culture analysis revealed that 40 (83.3%) were positive and the pathogens most commonly isolated included Coagulase-negative Staphylococcus (43.2%) and Staphylococcus aureus (25.0%), being 63.9% of the bacteria multiresistant. Antimicrobial test results demonstrated great sensitivity to gatifloxacin (97.2%), vancomycin (94.4%) and ofloxacin (94.4%).


CONCLUSIONS
Conjunctival bacterial flora among newborns in NICU is varied, mainly Gram-positive, usually multiresistant to antibiotics.
Endriss
Daniela
D
Hospital de Olhos de Pernambuco, Fundação Altino Ventura, Recife, PE, Brasil.
Brandt
Carlos Teixeira
CT
Castro
Célia Maria Machado Barbosa de
CM
Oliveira
Vladimir Fontes
VF
Diniz
Maria de Fátima Alves
Mde F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003030:Coagulase / Q000378:metabolism; D003228:Conjunctiva / Q000187:drug effects / Q000382:microbiology*; D003430:Cross-Sectional Studies; D003470:Culture Media; D024881:Drug Resistance, Bacterial; D005260:Female; D024841:Fluoroquinolones / Q000494:pharmacology; D000077734:Gatifloxacin; D006760:Hospitalization; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D008297:Male; D015242:Ofloxacin / Q000494:pharmacology; D011446:Prospective Studies; D013211:Staphylococcus aureus / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D003030:Coagulase; D003470:Culture Media; D024841:Fluoroquinolones; D014640:Vancomycin; D015242:Ofloxacin; D000077734:Gatifloxacin