Post-translational modifications in Plasmodium: more than you think!
Recent evidences indicate that transcription in Plasmodium may be hard-wired and rigid, deviating from the classical model of transcriptional gene regulation. Thus, it is important that other regulatory pathways be investigated as a comprehensive effort to curb the deadly malarial parasite. Research in post-translational modifications in Plasmodium is an emerging field that may provide new venues for drug discovery and potential new insights into how parasitic protozoans regulate their life cycle. Here, we discuss the recent findings of post-translational modifications in Plasmodium.
Chung
Duk-Won Doug
DW
Department of Cell Biology and Neuroscience, University of California, Riverside, 900 University Avenue, Riverside, CA 92521, USA.
Ponts
Nadia
N
Cervantes
Serena
S
Le Roch
Karine G
KG
D000818:Animals; D005786:Gene Expression Regulation; D010961:Plasmodium / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D015800:Protozoan Proteins / Q000378:metabolism*
D015800:Protozoan Proteins