title: [Summarization of tinea capitis cases encountered at a clinic in the past 5 years].
abstract: Twelve cases of tinea capitis were encountered at a clinic in Kumamoto prefecture between April 2004 and December 2008. Patients were boys aged between 2 and 18 in 11 cases, and a woman aged 50 years in 1 case. The pathogen was Microsporum canis in 6 cases, and Trichophyton tonsurans in 6 cases. In the cases with M. canis , patients were boys aged 2 to 8 years in 5 cases, and the type of disease was non-inflammatory in 5 cases and inflammatory in 1 case. The patients with T. tonsurans were boys aged 12 to 18 years (judo athletes in 5 cases) and the type of disease was inflammatory in 2 cases and black dot in 4 cases. Three of the M. canis cases were treated with oral administration of itraconazole (ITCZ) at doses of 2.4-4.0 mg/kg/day, and the other 3 with terbinafine hydrochloride (TBF) at doses of 2.6-4.6 mg/kg/day. The duration of treatment was 8-14 weeks with ITCZ, and 4-8 weeks with TBF. In the T. tonsurans cases, TBF was orally administered at doses of 1.4-2.4 mg/kg/day for a period of 8-12 weeks. In one case of non-inflammatory M. canis infection (Case 6) and one case of inflammatory T. tonsurans infection (Case 10), treatment was initiated with the dose recommended in Japan, but symptoms did not improve; therefore the dose was doubled according to European and American guidelines and the patients recovered. As tinea capitis frequently resists treatment, establishment of treatment guidelines is necessary.
authors: Division of Dermatology, Self Defense Force Kumamoto Hospital, Kumamoto, Japan.
authors: Yuko
authors: Y
authors: Kunitake
authors: Hiromitsu
authors: H
authors: Noguchi
authors: Masataro
authors: M
authors: Hiruma
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000935:Antifungal Agents / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D008864:Microsporum / Q000302:isolation & purification; D008875:Middle Aged; D009281:Naphthalenes / Q000008:administration & dosage; D017410:Practice Guidelines as Topic; D000077291:Terbinafine; D013997:Time Factors; D014006:Tinea Capitis / Q000145:classification / Q000188:drug therapy* / Q000382:microbiology*; D016896:Treatment Outcome; D014249:Trichophyton / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D017964:Itraconazole; D000077291:Terbinafine