title: Subsequent fracture after percutaneous vertebroplasty can be predicted on preoperative multidetector row CT.
abstract: OBJECTIVE
  Subsequent fracture is often seen after percutaneous vertebroplasty. The purpose of this prospective study was to evaluate preoperative multidetector row CT (MDCT) for the prediction of subsequent fractures after vertebroplasty.
  
  
  METHODS
  This study included 26 consecutive patients (18 women and 8 men) with osteoporotic compression fractures (58 vertebrae). A 64-section MDCT with multiplanar reformation was obtained 1 day before the procedure. Subsequent MR imaging was used to evaluate new fractures at least 3 months after treatment on a routine basis or if there was recurrent pain. We used logistic regression analysis with MDCT findings and clinical data for statistical evaluation according to the location of new fractures.
  
  
  RESULTS
  Subsequent fractures were noted at 14 adjacent vertebrae (12.1%) in 13 patients and at 14 remote vertebrae in 6 patients (23.1%). Subsequent fractures in adjacent vertebrae tended to occur in small vertebrae before treatment (P < .05). Steroid medication and low CT value in nonfractured vertebrae were associated with subsequent fractures in remote vertebrae (P < .05). Further collapse of the treated vertebral bodies was noted in 10 patients (11 vertebrae [19.0%]) without specific findings (P > .05).
  
  
  CONCLUSIONS
  The small size of the treated vertebrae may relate to subsequent fractures in adjacent vertebrae. Steroid use and low CT value of nonfractured vertebrae on preoperative MDCT can be associated with subsequent fractures in remote vertebrae.
authors: Department of Clinical Radiology, Kyushu University, Fukuoka, Japan. hiwatasi@radiol.med.kyushu-u.ac.jp
authors: A
authors: A
authors: Hiwatashi
authors: T
authors: T
authors: Yoshiura
authors: K
authors: K
authors: Yamashita
authors: H
authors: H
authors: Kamano
authors: T
authors: T
authors: Dashjamts
authors: H
authors: H
authors: Honda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D050815:Fractures, Compression / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D015552:Injections, Intralesional; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D016103:Spinal Fractures / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000706:statistics & numerical data; D054854:Vertebroplasty / Q000379:methods* / Q000706:statistics & numerical data