[Renal tumor size. Clinicomorphological correlations].
To reveal correlations between a renal tumor size and its clinical and morphological characteristics, we retrospectively analysed 263 case histories of patients with renal cell cancer. At a univariate analysis a maximal renal tumor size as a continuous variable significantly correlated with tumor differentiation, histological involvement of regional lymph nodes, presence of tumor necrosis, venous thrombosis, invasion into the collecting system, severity of clinical symptoms, 3- and 5-year cancer-specific survival. An increase of a tumor size, either as a continuous variable or a categorical one is accompanied with enhancement of tumor properties determining the outcome. The inclusion of a tumor size as a continuous parameter in the staging systems may have in the future a significant impact on accuracy of prediction of a renal cell cancer course and outcome, on specification of indications for various treatments.
Seregin
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AV
Loran
O B
OB
Ashugian
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VR
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007167:Immunotherapy; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009392:Nephrectomy / Q000379:methods; D011878:Radiotherapy; D012189:Retrospective Studies; D047368:Tumor Burden; D055815:Young Adult