title: Investigating the concurrent presence of HCV in serum, oral fluid and urine samples from chronic HCV patients in Faisalabad, Pakistan.
abstract: Hepatitis C virus (HCV) is normally present in the blood of infected patients; however, it can also be present in some other body fluids. Therefore, in this study, a concurrent presence of HCV-RNA was investigated in oral fluid and urine of 80 Pakistani chronic HCV patients. HCV-RNA was detected in 31 (38.8%) oral fluid and 10 (12.5%) urine samples using RT-PCR in all 80 of the patients whose sera tested positive for HCV-RNA. From this study, it is concluded that, in addition to the blood, HCV RNA can also be found in oral secretions as well as urine of chronic HCV patients.
authors: Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, P.O. Box 577, Jhang Road, Faisalabad, Pakistan. shafique_nibpk@yahoo.com
authors: Muhammad
authors: M
authors: Shafique
authors: Nasir
authors: N
authors: Ahmad
authors: Fazli R
authors: FR
authors: Awan
authors: Tanveer
authors: T
authors: Mustafa
authors: Mujib
authors: M
authors: Ullah
authors: Javed A
authors: JA
authors: Qureshi
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D016174:Hepacivirus / Q000235:genetics / Q000302:isolation & purification*; D019698:Hepatitis C, Chronic / Q000097:blood / Q000652:urine / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D012367:RNA, Viral / Q000032:analysis* / Q000097:blood / Q000652:urine; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012463:Saliva / Q000821:virology; D014556:Urine / Q000821:virology
chemical_list: D012367:RNA, Viral