The genesis and consequences of postprandial hyperglycemia.
Blood glucose levels after meals may be a misunderstood or overlooked aspect of management of type 2 diabetes. Emerging data suggest that postprandial glucose (PPG) excursions-meaning excessive increases in plasma glucose levels after meals-may be even more representative of overall glucose control than fasting glucose concentrations. In fact, evidence is accumulating that supports a close relationship between PPG levels and diabetes-related morbidity and mortality. Thus, interventions directed at postprandial glucose control could prove to be an effective and physiologic means of improving overall glucose homeostasis and reducing the incidence and progression of diabetic complications.
Dostou
J M
JM
Diabetes Care Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7172, USA. Jean_Dostou@med.unc.edu
Einhorn
D
D
D001786:Blood Glucose / Q000378:metabolism*; D048909:Diabetes Complications / Q000209:etiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism / Q000628:therapy; D018450:Disease Progression; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000209:etiology* / Q000517:prevention & control; D007328:Insulin / Q000172:deficiency / Q000378:metabolism; D000078790:Insulin Secretion; D012307:Risk Factors
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin