Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy.
A 23-year-old woman developed ischemic stroke (IS) 8 to 12 hours after ingestion of sumatriptan (ST) and then developed mucosal bleeding secondary to acute thrombocytopenia likely due to dipyridamole (DP) on the 10th day poststroke. Sumatriptan-associated IS and DP-induced thrombocytopenia are rare events in themselves and their sequential occurrence in the same patient is quite exceptional. We compare our case to other similar cases in the literature.
Adams
Carolyn
C
Care of the Elderly, Royal Preston Hospital, Preston, United Kingdom.
Dhirendra
Allen
A
Ames
Paul R J
PR
D000208:Acute Disease; D000328:Adult; D002545:Brain Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D004176:Dipyridamole / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D007049:Iatrogenic Disease; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D058825:Serotonin 5-HT1 Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D020521:Stroke / Q000139:chemically induced* / Q000188:drug therapy; D018170:Sumatriptan / Q000008:administration & dosage / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000188:drug therapy
D010975:Platelet Aggregation Inhibitors; D058825:Serotonin 5-HT1 Receptor Agonists; D004176:Dipyridamole; D018170:Sumatriptan