Rheumatoid arthritis associated with osteopetrosis.
Osteopetrosis is an inherited disorder characterized by reduced bone resorption. We here report a rare case of osteopetrosis associated with rheumatoid arthritis. The patient was diagnosed as autosomal dominant osteopetrosis type II in his youth and developed rheumatoid arthritis at 42 years of age. In spite of the severe inflammation and rapid progression of cartilage destruction, the progression of bone erosion was slow in this patient.
Kadono
Yuho
Y
Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Tanaka
Sakae
S
Nishino
Jinju
J
Nishimura
Keita
K
Nakamura
Ichiro
I
Miyazaki
Tsuyoshi
T
Takayanagi
Hiroshi
H
Nakamura
Kozo
K
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics; D015519:Bone Density / Q000235:genetics; D001862:Bone Resorption / Q000150:complications / Q000000981:diagnostic imaging / Q000235:genetics; D001842:Bone and Bones / Q000473:pathology*; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010022:Osteopetrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics; D011859:Radiography