Hepatic encephalopathy.
Hepatic encephalopathy is characterized by a wide spectrum of neuropsychiatric abnormalities and motor disturbances in patients with advanced liver disease. It is estimated to occur in 30% to 45% of patients with liver cirrhosis and in 10% to 50% of patients with transjugular intrahepatic portosystemic shunts. It can be seen in cancer patients due to multiple factors. Early diagnosis and treatment are important but can be challenging, especially in mild forms with subtle findings. This article reviews the pathogenesis, diagnostic criteria, grading, and management of hepatic encephalopathy.
Eroglu
Yasemen
Y
Division of Pediatric Gastroenterology, Department of Pediatrics, Oregon Health & Science University, CDRCP, Portland, OR 97239, USA. erogluy@ohsu.edu
Byrne
William J
WJ
D000970:Antineoplastic Agents / Q000009:adverse effects; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006501:Hepatic Encephalopathy / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D019586:Intracranial Hypertension / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D017114:Liver Failure, Acute / Q000150:complications; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000150:complications / Q000473:pathology; D011379:Prognosis; D012720:Severity of Illness Index
D000970:Antineoplastic Agents