title: Novel polymorphism of RecA fibrils revealed by atomic force microscopy.
abstract: RecA fibrils in physiological conditions have been successfully imaged using Tapping Mode atomic force microscopy. This represents the first time images of recA have been obtained without drying, freezing and/or exposure to high vacuum conditions. While previously observed structures - the monomer, the hexamer, the short rod - were seen, a new type of fibril was also observed. This protofibril is narrower in diameter than the standard fibril, and occurs in three distinct morphologies: aperiodic, 100-nm periodic, and 150-nm periodic. In addition, much longer rods were observed, and appear curved and even circular.
authors: Department of Chemistry, University of Toronto, Toronto, ON M5S 3H6, Canada.
authors: Bernie D
authors: BD
authors: Sattin
authors: M Cynthia
authors: MC
authors: Goh