Antifungal activity of bioactive triterpenoid saponin from the seeds of Cassia angustifolia.
A novel oleanen type triterpenoid glycoside has been isolated from butanolic seed extracts of Cassia angustifolia. Its structure was elucidated as 3-O-{beta-D-glucuronopyranosyl-(1 --> 4)-[beta-D-galactopyranosyl-(1 --> 2)]-beta-D-xylopyranosyl-(1 --> 3)-beta-D-glucopyranosyl}-2, 16alpha-dihydroxy-4, 20-hydroxy methyl olean-12-ene-28-oic acid on the basis of spectral evidence (i.e. FTIR, (1)H NMR, (13)C NMR and FAB-MS data). The isolated saponin was tested for its antifungal activity, where the maximum inhibition was found in Colletotrichium dematium.
Khan
Noor Afshan
NA
Department of Postgraduate and Research in Chemistry, Rani Durgawati University, Jabalpur, India. noor_afshan25@yahoo.com
Srivastava
Ashutosh
A
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry*; D029846:Senna Plant / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes