title: Re-osseointegration on previously contaminated surfaces: a systematic review.
abstract: OBJECTIVE
  The aim of this review was to search the literature for the existing evidence of re-osseointegration after treatment of peri-implantitis at contaminated implant surfaces.
  
  
  METHODS
  A search of PubMed as well as additional hand search of articles were conducted. Publications and articles accepted for publication up to November 2008 were included.
  
  
  RESULTS
  A total of 25 animal studies fulfilled the inclusion criteria for this review. Access surgery with closed healing has been observed to positively influence the rate of re-osseointegration when compared with non-surgical decontamination of the implant surface with open healing. Open debridement including surface decontamination may result in re-osseointegration and this integration was more pronounced on rougher than on smooth implant surfaces. The adjunctive use of regenerative procedures resulted in varying amounts of re-osseointegration.
  
  
  CONCLUSIONS
  Re-osseointegration is possible to obtain on a previously contaminated implant surface and can occur in experimentally induced peri-implantitis defects following therapy. The amount of re-osseointegration, varied considerably within and between studies. Implant surface characteristics may influence the degree of re-osseointegration. Surface decontamination alone can not achieve substantial re-osseointegration on a previously contaminated implant surface. No method predictably accomplished complete resolution of the peri-implant defect.
authors: Department of Health Sciences, Kristianstad University, Sweden. stefan.renvert@hkr.se
authors: Stefan
authors: S
authors: Renvert
authors: Ioannis
authors: I
authors: Polyzois
authors: Rory
authors: R
authors: Maguire
mesh_terms: D000818:Animals; D003646:Debridement; D015921:Dental Implants / Q000382:microbiology*; D004285:Dogs; D048091:Guided Tissue Regeneration; D000882:Haplorhini; D016348:Osseointegration; D010518:Periodontitis / Q000382:microbiology* / Q000601:surgery / Q000628:therapy; D012086:Reoperation; D013499:Surface Properties
chemical_list: D015921:Dental Implants