title: The relationship between microalbuminuria and the presence and extent of coronary atherosclerosis.
abstract: OBJECTIVE
  To evaluate the relationship between microalbuminuria (MA) and the presence and extent of coronary artery disease (CAD).
  
  
  METHODS
  Four hundred and two consecutive patients were divided into 4 groups based on the presence of diabetes mellitus (DM) and MA: DM(+)/MA(+), DM(+)/MA(-), DM(-)/MA(+), and DM(-)/MA(-). Severity of CAD was assessed by the Gensini scoring system.
  
  
  RESULTS
  The Gensini score was 57 +/- 38.2 vs 16.5 +/- 19.5 (P < .001) in the DM(+)/MA(+) and DM(+)/MA(-) groups and 45 +/- 39.8 vs 9.9 +/- 16.6 (P < .001) in the DM(-)/MA(+) and DM(-)/MA(-) groups. Spearman correlation analysis demonstrated a positive relation between urine albumin/creatinine ratio (ACR) and extent of CAD both in the diabetic and nondiabetic patients (r = .584, P = .001; r = .545, P = .001). Microalbuminuria was found to be an independent predictor for the presence (OR for MA: 3.728; 95% CI, 1.931-7.196; P < .001) and severity of CAD (P < .001, beta = .563).
  
  
  CONCLUSIONS
  A strong relationship between MA and the severity of CAD was reported.
authors: Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey. onurdeveci@yahoo.co.uk
authors: Onur Sinan
authors: OS
authors: Deveci
authors: Giray
authors: G
authors: Kabakci
authors: Erol
authors: E
authors: Tulumen
authors: Sercan
authors: S
authors: Okutucu
authors: Hakan
authors: H
authors: Aksoy
authors: Ergun Baris
authors: EB
authors: Kaya
authors: Ugur
authors: U
authors: Canpolat
authors: Kudret
authors: K
authors: Aytemir
authors: Lale
authors: L
authors: Tokgozoglu
authors: Ali
authors: A
authors: Oto
mesh_terms: D000368:Aged; D000419:Albuminuria / Q000453:epidemiology*; D015897:Comorbidity; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000652:urine; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000652:urine; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000652:urine; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged