[Anti-rabies measures by the Infectious Disease Prevention Service at the "La Sapienza" University of Rome in the years 2005-2007].
Antirabies service activities of the Infectious Diseases Prophylaxis Centre of the Sapienza University of Rome during the period 2005-2007. Authors analyzed data, of antirabies activity, from 3206 patients treated at the Infectious Diseases Prophylaxis Centre of the University of Rome "La Sapienza" during the period 2005-2007 Dogs were responsible for most bites (92.1%). All patients went first to the Emergency Room where tetanus prophylaxis was administrated only with specific immunoglobulins (51.5%): to such patients we suggested to implement prophylaxis with vaccination. For other patients (19.4%) we prescribed only vaccine tetanus prophylaxis. Antirabies vaccine (PCEC) has been injected in 604 patients (18.8%). Rabies immunoglobulins have been prescribed only to 11 (0.4%) patients that were bitten during travel to Asia or Africa (0.4%). The authors emphasize the opportunity to reduce the administration of anti-tetanus immunoglobulin in Emergency Room by a deeper evaluation of patient's immunity; moreover the authors confirm a clear quantitative reduction of prophylactic interventions against rabies in Italy.
Tzantzoglou
S
S
Dipartimento di Malattie Infettive e Tropicali, Sapienza Università di Roma.
Franchi
C
C
Pezzella
M
M
Traditi
F
F
Monacelli
M
M
D000046:Academic Medical Centers; D000328:Adult; D000818:Animals; D001733:Bites and Stings / Q000628:therapy*; D004359:Drug Therapy, Combination; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage; D007155:Immunologic Factors / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D011314:Preventive Health Services / Q000706:statistics & numerical data*; D011818:Rabies / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000008:administration & dosage*; D012189:Retrospective Studies; D012384:Rome / Q000453:epidemiology; D013742:Tetanus / Q000517:prevention & control; D013743:Tetanus Antitoxin / Q000008:administration & dosage
D007136:Immunoglobulins; D007155:Immunologic Factors; D011819:Rabies Vaccines; D013743:Tetanus Antitoxin