[Hydroa vacciniforme-like cutaneous T cell lymphoma: a case report and literature review].
OBJECTIVE
To study the clinical features, diagnosis and therapy of hydroa vacciniforme-like cutaneous T cell lymphoma.


METHODS
The clinical presentations and the findings of laboratory examinations and skin biopsy of affected tissue in a child with hydroa vacciniforme-like cutaneous T cell lymphoma were retrospectively reviewed.


RESULTS
The child manifested as rash, fever and lymph node intumesce. Rash was pantomorphia, including edematous erythema, vesicles, crusts, necrosis and depressed scar, and it was mild in winter and severe in summer, mainly involving in the face and extremities. Epstein-Barre virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3 (+), CD43 (+), CD20 (-), pax-5 (-), TIA (+), CD5 (+), CD8 (+), Granmye (+) and CD4 (-). The clinical symptoms were improved after glucocorticoid treatment in this child.


CONCLUSIONS
Hydroa vacciniforme-like cutaneous T cell lymphoma has special clinical manifestations. This disorder may be definitely diagnosed by skin biopsy of affected tissue and immunohistochemistry assay. Glucocorticoid treatment is effective. EBV infection may be related to the development of this disorder.
Li
Hai-Ying
HY
Department of Pediatrics, First Teaching Hospital of Zhengzhou University, Zhengzhou 450052, China.
Wang
Huai-Li
HL
Gao
Tie-Zheng
TZ
Zhuo
Zhi-Hong
ZH
Li
Dao-Ming
DM
Li
Hui-Xiang
HX
D002675:Child, Preschool; D005260:Female; D006801:Humans; D006837:Hydroa Vacciniforme / Q000473:pathology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*