title: Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: report of a workshop.
abstract: The issues of antivenom stability and distribution, and the training of health staff in the correct use of antivenoms in Latin America were discussed in a workshop held at Instituto Clodomiro Picado, Costa Rica, in September 16-19, 2008, under the auspices of the program CYTED. Participants from public antivenom production laboratories of the region, together with representatives of the Ministries of Health, from Argentina, Paraguay, Brazil, Bolivia, Perú, Ecuador, Colombia, Venezuela, Panamá, Costa Rica and Nicaragua participated in the event. Technical advances in the study of antivenom stability and in the design of novel formulations aimed at generating products of higher stability were presented. In addition, antivenom acquisition and distribution systems in every country were presented and discussed, together with novel tools that could be useful for improving antivenom distribution, such as the software SIGEpi, developed by the Pan American Health Organization. The issue of the cold chain, as well as the most frequent causes of misuse of antivenoms in the region, were also analyzed. Finally, the experiences of training programs for health staff on the correct use of antivenoms in snakebite envenomation treatment in Latin America were presented. It was concluded that, in addition to the fostering of antivenom production and quality control, renewed efforts should be implemented at improving the stability, distribution and correct use of antivenoms in the region.
authors: Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, 1000 San José, Costa Rica. jgutierr@icp.ucr.ac.cr
authors: José María
authors: JM
authors: Gutiérrez
authors: Hui Wen
authors: HW
authors: Fan
authors: Carmen L M
authors: CL
authors: Silvera
authors: Yamileth
authors: Y
authors: Angulo
mesh_terms: D000997:Antivenins / Q000737:chemistry / Q000627:therapeutic use*; D004355:Drug Stability; D006801:Humans; D007843:Latin America; D012909:Snake Bites / Q000628:therapy*; D012910:Snake Venoms / Q000276:immunology*
chemical_list: D000997:Antivenins; D012910:Snake Venoms