title: Stereoselective Synthesis of Quaternary Proline Analogues.
abstract: This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of alpha-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The diverse synthetic approaches are classified according to the bond which is formed to complete the quaternary skeleton.
authors: Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain.
authors: M Isabel
authors: MI
authors: Calaza
authors: Carlos
authors: C
authors: Cativiela