Farinomalein, a maleimide-bearing compound from the entomopathogenic fungus Paecilomyces farinosus.
A new maleimide-bearing compound, farinomalein (1), was isolated from the entomopathogenic fungus Paecilomyces farinosus HF599. The structure was determined on the basis of spectroscopic analyses and chemical conversion. Compound 1 showed potent activity (5 mug/disk) against the plant pathogenic Phytophthora sojae P6497.
Putri
Sastia P
SP
International Center for Biotechnology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kinoshita
Hiroshi
H
Ihara
Fumio
F
Igarashi
Yasuhiro
Y
Nihira
Takuya
T
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000382:microbiology; D007915:Lepidoptera / Q000382:microbiology; D008301:Maleimides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009868:Oomycetes / Q000187:drug effects; D010143:Paecilomyces / Q000737:chemistry*; D010838:Phytophthora / Q000187:drug effects*
D000935:Antifungal Agents; D008301:Maleimides; C543955:farinomalein; C043592:maleimide