title: Nasal NK/T-cell lymphoma in the paediatric population. Two case reports.
abstract: Nasal natural killer (NK)/T-cell lymphoma is an uncommon disease, and only a few paediatric cases are found in the literature. We report 2 cases of NK/T-cell lymphoma occurring in children. The primary site was the the nasal cavity in the first case (5-year-old girl) and the tonsil in the second case (4-year-old boy). Histological study showed a polymorphic neoplastic infiltrate with an angioinvasive pattern and T-cell phenotype. Ebstein-barr virus infection was established by in situ hybridization. Both underwent an aggressive chemotherapy regimen. The outcome was favorable for the 4-year old boy; however, the 5-year-old girl died two months after diagnosis.
authors: *Department of Otorhinolaryngology, Farhat Hached Hospital, Sousse, Tunisia. izeglaoui@yahoo.fr
authors: I
authors: I
authors: Zeglaoui
authors: M
authors: M
authors: Belcadhi
authors: B
authors: B
authors: Sriha
authors: K
authors: K
authors: Bouzouita
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D054391:Lymphoma, Extranodal NK-T-Cell / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D014067:Tonsillar Neoplasms / Q000175:diagnosis* / Q000628:therapy*