Primary cutaneous CD30+ lymphoproliferative disorder--a 10-year follow-up. A case report and differential diagnosis.
Primary cutaneous CD30+ lymphoproliferative disorders (LPDs) are the second most common group of primary cutaneous T-cell lymphomas (CTCLs). The spectrum of LPDs includes lymphomatoid papulosis (LyP), primary cutaneous anaplastic large cell lymphoma (C-ALCL) and borderline cases. The term "borderline lesions" refers to cases where histological features are similar to LyP, but clinically behave as C-ALCL, or to cases where histological features are typical for C-ALCL, but clinically behave as LyP. We present a clinical and morphological picture of LPD in a 57-year old patient treated in the Department of Oncology and of a relapse after ten years of follow-up and discuss clinical and morphological differential diagnosis and the significance of such diagnosis.
Szpor
Joanna
J
Department of Pathomorphology, Jagiellonian University Medical College, Kraków. lymphonix@cm-uj.krakow.pl
Dyduch
Grzegorz
G
Gałazka
Krystyna
K
Bahyrycz
Jan
J
Stój
Anastazja
A
Tomaszewska
Romana
R
D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism*; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D017731:Lymphomatoid Papulosis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
D017730:Ki-1 Antigen