Diagnosis and treatment of pediatric patients with late-onset portal vein stenosis after living donor liver transplantation.
Portal vein stenosis (PVS) after living donor liver transplantation (LDLT) is a serious complication that can lead to graft failure. Few studies of the diagnosis and treatment of late-onset (> or = 3 months after liver transplantation) PVS have been reported. One hundred thirty-three pediatric (median age 7.6 years, range 1.3-26.8 years) LDLT recipients were studied. The patients were followed by Doppler ultrasound (every 3 months) and multidetector helical computed tomography (once a year). Twelve patients were diagnosed with late-onset PVS 0.5-6.9 years after LDLT. All cases were successfully treated with balloon dilatation. Five cases required multiple treatments. Early diagnosis of late-onset PVS and interventional radiology therapy treatment may prevent graft loss.
Kawano
Youichi
Y
Department of Transplant Surgery, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan. y-kawano@jichi.ac.jp
Mizuta
Koichi
K
Sugawara
Yasuhiko
Y
Egami
Satoshi
S
Hisikawa
Shuji
S
Sanada
Yukihiro
Y
Fujiwara
Takehito
T
Sakuma
Yasunaru
Y
Hyodo
Masanobu
M
Yoshida
Yoshiyuki
Y
Yasuda
Yoshikazu
Y
Sugimoto
Eiji
E
Kawarasaki
Hideo
H
D000293:Adolescent; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D019520:Living Donors; D008297:Male; D011169:Portal Vein / Q000503:physiopathology*; D011183:Postoperative Complications; D015642:Radiology, Interventional / Q000379:methods; D012189:Retrospective Studies; D013997:Time Factors; D036542:Tomography, Spiral Computed / Q000379:methods; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000209:etiology*
D000925:Anticoagulants