title: The Systems Biology Graphical Notation.
abstract: Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling.
authors: EMBL European Bioinformatics Institute, Hinxton, UK. lenov@ebi.ac.uk
authors: Nicolas
authors: N
authors: Le Novère
authors: Michael
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authors: Hucka
authors: Huaiyu
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authors: Mi
authors: Stuart
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authors: Moodie
authors: Falk
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authors: Schreiber
authors: Anatoly
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authors: Sorokin
authors: Emek
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authors: Demir
authors: Katja
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authors: Wegner
authors: Mirit I
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authors: Aladjem
authors: Sarala M
authors: SM
authors: Wimalaratne
authors: Frank T
authors: FT
authors: Bergman
authors: Ralph
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authors: Gauges
authors: Peter
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authors: Ghazal
authors: Hideya
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authors: Kawaji
authors: Lu
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authors: Yukiko
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authors: Matsuoka
authors: Alice
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authors: Villéger
authors: Sarah E
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authors: Boyd
authors: Laurence
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authors: Calzone
authors: Melanie
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authors: Courtot
authors: Ugur
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authors: Dogrusoz
authors: Tom C
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authors: Freeman
authors: Akira
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authors: Funahashi
authors: Samik
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authors: Ghosh
authors: Akiya
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authors: Jouraku
authors: Sohyoung
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authors: Kim
authors: Fedor
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authors: Kolpakov
authors: Augustin
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authors: Luna
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authors: Sahle
authors: Esther
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authors: Schmidt
authors: Steven
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authors: Watterson
authors: Guanming
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authors: Wu
authors: Igor
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authors: Goryanin
authors: Douglas B
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authors: Kell
authors: Chris
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authors: Sander
authors: Herbert
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authors: Sauro
authors: Jacky L
authors: JL
authors: Snoep
authors: Kurt
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authors: Kohn
authors: Hiroaki
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authors: Kitano
mesh_terms: D003196:Computer Graphics / Q000266:history; D049673:History, 20th Century; D020407:Internet; D012984:Software; D049490:Systems Biology / Q000266:history