A case of botryoid-type embryonal rhabdomyosarcoma.
We describe an infant with a congenital polypoid anal mass, diagnosed as botryoid-type embryonal rhabdomyosarcoma. Histological examination revealed myxoma-like appearance and cells with greater differentiation with elongated streaming eosinophilic cytoplasm and one or two nuclei, suggestive of rhabdomyoblasts. Tumour cells were strongly immunoreactive for desmin and 10% of cells displayed immunoreactivity for myoglobin. We present this case with a view to highlighting the benign clinical and histological appearance of botryoid-type embryonal rhabdomyosarcoma. Early biopsy is essential for improving prognosis.
Lee
M-W
MW
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. miumiu@www.amc.seoul.kr
Chung
W-K
WK
Choi
J-H
JH
Moon
K-C
KC
Koh
J-K
JK
D001005:Anus Neoplasms / Q000151:congenital / Q000188:drug therapy / Q000473:pathology*; D003893:Desmin / Q000032:analysis; D055088:Early Detection of Cancer; D006801:Humans; D007223:Infant; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D011379:Prognosis; D018233:Rhabdomyosarcoma, Embryonal / Q000188:drug therapy / Q000473:pathology*
D003893:Desmin; D009363:Neoplasm Proteins