Long-term stability of ethanol solutions for breath-alcohol tests.
Aqueous alcohol solutions in conjunction with a simulator are used commonly to calibrate and check the operation of breath-alcohol instruments. In Ohio, these solutions expire one year from the date of manufacture. This study was undertaken to review and report the stability of several batches of solution that had been manufactured from 2003 to 2007 and were statutorily expired. Eight batches of solution, each with a theoretical breath-alcohol target value of 0.100 g/210 L, were tested on paired Intoxilyzer 8000s using Guth model 590 simulators. This model of simulator required only 250 mL of solution per simulator. Therefore, each batch was evaluated by testing a single bottle of solution that had remained sealed since its manufacture. Five tests were performed on each instrument, and the acceptable criterion was limited to +/- 0.005 g/210 L of the established target value. A current batch of solution was also examined to verify the performance of the instrument before study sample testing commenced and at the completion of testing. All batches and bottles produced acceptable results within the acceptable limit for each target value. It can be concluded that the stability of the wet bath solution packaged in high-density polyethylene bottles with a theoretical concentration of 0.100 g/210 L is in excess of five years and surpasses the statutory expiration term of one year from the date of manufacture when stored at normal room temperatures.
Kucmanic
John
J
Ohio Department of Health/Bureau of Alcohol and Drug Testing, Akron, Ohio 44308, USA.
D001944:Breath Tests; D004355:Drug Stability; D000431:Ethanol / Q000737:chemistry*; D006801:Humans; D007202:Indicators and Reagents; D012996:Solutions; D013048:Specimen Handling; D013696:Temperature
D007202:Indicators and Reagents; D012996:Solutions; D000431:Ethanol