title: Low-risk lumbar skin stigmata in infants: the role of ultrasound screening.
abstract: OBJECTIVE
  To reassess the utility and validity of ultrasound (US) screening in infants with lumbar midline skin stigmata (MSS) that may be associated with tethering of the spinal cord.
  
  
  METHODS
  We conducted a prospective observational study of 254 infants under age 6 months with suspicious dorsal MSS between 2005 and 2007. All infants were examined by US and neurosurgical clinical evaluation, and 50 infants also underwent magnetic resonance imaging (MRI). The US and MRI findings were analyzed for correlation. Associations between the imaging findings and the presence of the low-risk skin lesions simple dimple (113 cases) and deviated gluteal fold (DGF; 44 cases) also were evaluated.
  
  
  RESULTS
  Analysis of US and MRI results for the cohort of 50 neonates in whom both examinations were performed showed high concordance. The low-risk group of infants with simple dimple and DGF constituted 157 US procedures, 96% of which were of high quality, providing clear visualization of spinal components. None demonstrated any clinically significant pathological findings.
  
  
  CONCLUSIONS
  Our data reaffirm the reliability of US as a screening tool for tethered cord syndrome. Infants with low-risk lesions, such as simple dimple and DGF, may be absolved from US screening, because these findings alone do not indicate underlying pathological lesions. We propose a simplified diagnostic classification system for MSS.
authors: Department of Radiology, DANA Children's Hospital, Tel Aviv Sourasky Medical Center, Israel. Bensira@tasmc.health.gov.il
authors: Liat
authors: L
authors: Ben-Sira
authors: Penina
authors: P
authors: Ponger
authors: Elka
authors: E
authors: Miller
authors: Liana
authors: L
authors: Beni-Adani
authors: Shlomi
authors: S
authors: Constantini
mesh_terms: D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D015997:Neonatal Screening; D009436:Neural Tube Defects / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012307:Risk Factors; D014463:Ultrasonography