Potential bias in ophthalmic pharmaceutical clinical trials.
To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clinical results.
Varner
Paul
P
John J Pershing Veterans' Administration Medical Center, Poplar Bluff, Missouri, USA. paul.varner@va.gov