title: Headache attributed to intracranial tumours: a prospective cohort study.
abstract: Between January 2007 and March 2008, we prospectively studied all patients operated on for intracranial tumours in our Department of Neurosurgery. Preoperatively, all patients were interviewed by a neurologist to collect headache characteristics. Measurements of tumour and oedema volume were made using dedicated software for magnetic resonance imaging studies. Tumour histopathology was established by histological examination postoperatively. If headache improved postoperatively, a diagnosis of 'headache attributed to intracranial neoplasm' was made, according to the 2004 International Classification of Headache Disorders (ICHD-II). A multivariate logistic regression model was used to evaluate the association of headache with potential risk factors. We studied 206 subjects. The prevalence of tumour headache was 47.6%. Intracranial tumour headache was non-specific and in most cases could not be classified by current ICHD-II diagnostic criteria for primary headache syndromes. Its prevalence varied depending on volume, location and type of tumour, as well as on the patient's previous headache history.
authors: Department of Neurology, Santa Maria della Misericordia University-Hospital, Udine, Italy. luca.valentinis@tin.it
authors: L
authors: L
authors: Valentinis
authors: F
authors: F
authors: Tuniz
authors: F
authors: F
authors: Valent
authors: M
authors: M
authors: Mucchiut
authors: D
authors: D
authors: Little
authors: M
authors: M
authors: Skrap
authors: P
authors: P
authors: Bergonzi
authors: G
authors: G
authors: Zanchin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D015331:Cohort Studies; D005260:Female; D006261:Headache / Q000145:classification / Q000453:epidemiology* / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult