[Biofabrication with chitosan and its application progress].
Chitosan is a polymer with good biocompatibility, unique pH-responsive solubility, convenient modification and easier film-formability. Chitosan could serve as an active mediator between biological components and microfabricated devices to prepare biological micro electro mechanical systems (BioMEMS) with high selectivity and sensitivity. Recently, there has been a growing interest in BioMEMS based on biofabrication of chitosan. We reviewed the mechanisms and processes of three biofabrication methods based on chitosan, including directed assembly, enzymatic assembly and self-assembly. Current applications and research progress in biological, medical and environmental fields are also discussed. Finally, future research directions are prospected.
Meng
Fanping
F
College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China. fanpingm@tom.cn
Zhang
Aijing
A
D001672:Biocompatible Materials / Q000737:chemistry*; D032701:Biomimetics; D015374:Biosensing Techniques; D002384:Catalysis; D048271:Chitosan / Q000737:chemistry*; D055617:Micro-Electrical-Mechanical Systems / Q000379:methods*; D036103:Nanotechnology; D009693:Nucleic Acid Hybridization
D001672:Biocompatible Materials; D048271:Chitosan