[Proteomics and biomarkers for detection of ovarian cancer].
OBJECTIVE
The purpose of this study was to focuse on recent developments on the evolving field of biomarker discovery and validation techniques using proteomics platforms for ovarian cancer.


METHODS
Review.


METHODS
Department of Obstetrics and Gynecology Medical Faculty Charles University Hradec Kralove. Institute of Molecular Pathology. Faculty of Military Health Sciences, University of Defense, Hradec Kralove.


METHODS
The last decade has seen major changes in the technologies used to identify markers for diagnosing early stages of ovarian cancer. Currently the major developments were made in three distinct areas: protein profilig, highthroughput validation techniques and solid and liquid phase protein microarray platforms for analyzing candidate markers across stages hold significant of ovarian cancer. These new technologies hold significant promise in identifying more robust markers for ovarian cancer.


CONCLUSIONS
The present review summarizes the results of clinical and experimental research on biomarkers of ovarian cancer.
Kacerovský
M
M
Lékarská fakulta Hradec Králové, Univerzita Karlova Praha.
Tambor
V
V
Lenco
J
J
Tosner
J
J
D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000235:genetics; D040081:Protein Array Analysis; D040901:Proteomics / Q000379:methods
D014408:Biomarkers, Tumor