title: Problems with RCT design.
authors: John L
authors: JL
authors: Hayes
mesh_terms: D000367:Age Factors; D055094:Evidence-Based Dentistry; D006801:Humans; D008312:Malocclusion, Angle Class II / Q000628:therapy; D017289:Orthodontic Appliances, Functional; D009972:Orthodontics, Interceptive / Q000295:instrumentation; D016032:Randomized Controlled Trials as Topic; D012107:Research Design