title: Intracardiac metastasis of a Malignant Mixed Mullerian tumor (MMMT): progressive dyspnoea due to obstruction of the left atrium and the left ventricle without left ventricular dysfunction or primary lung disease.
abstract: Malignant Mixed Mullerian tumors (MMMT) are rare gynecological tumors. Even with surgical treatment, chemotherapy, and/or radiotherapy, outcome is poor. MMMTs are known to metastasize to the liver, the abdomen, and the lungs. One case of an ocular metastasis has been reported. In a 61-year-old female patient who had undergone surgical resection of a Mullerian tumor of the uterus 26 months prior to being admitted to our department, we found an obstructing left atrial mass. Histopathologic assessment of this lesion after surgical resection revealed a Mullerian tumor metastasis. Immediately after surgery, the patient was asymptomatic, but was readmitted 4 months later with dyspnoea. Echocardiography and CT revealed new masses in the left atrium and left ventricle. On a literature review, we did not find any description of left atrial and left ventricular occluding metastases of MMMT.
authors: Department of Cardiology, Marienhospital Bottrop, Bottrop, Germany. L.J.Ulbricht@web.de
authors: Ludger J
authors: LJ
authors: Ulbricht
authors: Matthias
authors: M
authors: Kunert
authors: Bernhard
authors: B
authors: Gremmler
authors: Nikolaos
authors: N
authors: Evagelopoulos
authors: Arno
authors: A
authors: Krian
authors: Jürgen
authors: J
authors: Moege
mesh_terms: D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology*; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D005260:Female; D006325:Heart Atria / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000556:secondary* / Q000601:surgery; D010166:Palliative Care; D014057:Tomography, X-Ray Computed; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D016277:Ventricular Function, Left / Q000502:physiology*