title: Papillary tumor of the pineal region--a recently described entity: a report of three cases and review of the literature.
abstract: BACKGROUND
  The papillary tumor of the pineal region (PTPR) is a distinct clinicopathologic entity, the exact biological behavior of which is not known.
  
  
  RESULTS
  In the present report we describe 3 additional cases of PTPR because of its rarity. During a study period of 4 years (between January 2003 and December 2006), we diagnosed three cases of papillary tumor of the pineal region (PTPR). Clinico-radio-pathologic examination was done and follow-up was assessed. Microscopically, all 3 cases showed uniform morphology and consisted of papillary and solid areas. Immunohistochemistry showed strong and diffuse positivity for synaptophysin, NSE, chromogranin A, S-100 protein, MAP-2 and cytokeratin.
  
  
  CONCLUSIONS
  PTPR is a distinct entity and needs to be differentiated from other tumors of the pineal region as the biological behavior of this tumor is not fully understood. Radiologically this tumor can sometimes be misdiagnosed as tectal glioma.
authors: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India. sharmamehar@yahoo.co.in
authors: M C
authors: MC
authors: Sharma
authors: D
authors: D
authors: Jain
authors: C
authors: C
authors: Sarkar
authors: V
authors: V
authors: Suri
authors: A
authors: A
authors: Garg
authors: B S
authors: BS
authors: Sharma
authors: V S
authors: VS
authors: Mehta
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D010870:Pineal Gland / Q000378:metabolism* / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor