MicroRNAs: new players in acute myeloid leukaemia.
MicroRNAs (miRNAs) are short non-coding RNAs that have key functions in a wide array of critical cell processes, including haematopoiesis by regulating the expression of multiple genes. Aberrant miRNA expression has been described in acute myeloid leukaemia suggesting a role in leukaemogenesis. In this review we summarise the current knowledge.
Havelange
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Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Garzon
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Croce
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CM
D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000235:genetics* / Q000378:metabolism / Q000628:therapy; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism*; D011379:Prognosis
D035683:MicroRNAs