MREIT conductivity imaging of the postmortem canine abdomen using CoReHA.
Magnetic resonance electrical impedance tomography (MREIT) is a new bio-imaging modality providing cross-sectional conductivity images from measurements of internal magnetic flux densities produced by externally injected currents. Recent experimental results of postmortem and in vivo imaging of the canine brain demonstrated its feasibility by showing conductivity images with meaningful contrast among different brain tissues. MREIT image reconstructions involve a series of data processing steps such as k-space data handling, phase unwrapping, image segmentation, meshing, modelling, finite element computation, denoising and so on. To facilitate experimental studies, we need a software tool that automates these data processing steps. In this paper, we summarize such an MREIT software package called CoReHA (conductivity reconstructor using harmonic algorithms). Performing imaging experiments of the postmortem canine abdomen, we demonstrate how CoReHA can be utilized in MREIT. The abdomen with a relatively large field of view and various organs imposes new technical challenges when it is chosen as an imaging domain. Summarizing a few improvements in the experimental MREIT technique, we report our first conductivity images of the postmortem canine abdomen. Illustrating reconstructed conductivity images, we discuss how they discern different organs including the kidney, spleen, stomach and small intestine. We elaborate, as an example, that conductivity images of the kidney show clear contrast among cortex, internal medulla, renal pelvis and urethra. We end this paper with a brief discussion on future work using different animal models.
Jeon
Kiwan
K
Department of Mathematical Sciences, KAIST, Daejeon, Korea.
Minhas
Atul S
AS
Kim
Young Tae
YT
Jeong
Woo Chul
WC
Kim
Hyung Joong
HJ
Kang
Byeong Teck
BT
Park
Hee Myung
HM
Lee
Chang-Ock
CO
Seo
Jin Keun
JK
Woo
Eung Je
EJ
D000005:Abdomen / Q000033:anatomy & histology*; D000465:Algorithms; D000818:Animals; D004285:Dogs; D017097:Electric Impedance; D005260:Female; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male