Optimization and oxidative stability of the microencapsulated conjugated linoleic acid.
We used response surface methodology to optimize the preparation conditions of conjugated linoleic acid (CLA) microcapsules for maximum entrapment efficiency. Three independent variables were used: the ratio of CLA core material to agar and waxy corn starch wall material (X(1)), the temperature of dispersion fluid (X(2)), and the concentration of emulsifier (X(3)). The optimized values of X(1), X(2), and X(3) were found to be 3.82:6.18, 19.97 degrees C, and 0.34%, respectively. The CLA oxidation stability was significantly protected by microencapsulation. These results suggest that CLA-loaded microcapsules can be used as a means to enhance not only the entrapment efficiency but also the oxidative stability of CLA.
Lee
Ji-Soo
JS
Department of Food and Nutrition, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Republic of Korea.
Song
Young-Bin
YB
Lee
Ji Yeon
JY
Kim
Mi Kyung
MK
Jun
Soo Jin
SJ
Lee
Hyeon Gyu
HG
D002214:Capsules; D004337:Drug Carriers / Q000737:chemistry; D044243:Linoleic Acids, Conjugated / Q000737:chemistry*; D010084:Oxidation-Reduction; D010545:Peroxides / Q000737:chemistry; D013499:Surface Properties
D002214:Capsules; D004337:Drug Carriers; D044243:Linoleic Acids, Conjugated; D010545:Peroxides