Assessment of trace element concentration distribution in human placenta by wavelength dispersive X-ray fluorescence: effect of neonate weight and maternal age.
Trace element status in human placenta is dependent on maternal-neonatal characteristics. This work was undertaken to investigate the correlation between essential trace element concentrations in the placenta and maternal-neonatal characteristics. Placenta samples were collected from total 61 healthy mothers at gestation between 37 and 41 weeks. These samples were investigated with the restriction that the mother's age was 20-40 years old and the neonate's weight was 1-4kg. Percent concentrations of trace elements were determined using wavelength dispersive X-ray fluorescence (WDXRF). The placenta samples were prepared and analyzed without exposure to any chemical treatment. Concentrations of Fe, Cu and Zn in placenta tissues were found statistically to vary corresponding to the age of the mother and weight of the neonate. In the subjects, the concentration of Fe and Cu were increased in heavier neonates (p<0.05) and the concentration of Zn was increased with increasing mother age (p<0.05). Consequently, the Fe, Cu and Zn elements appear to have interactive connections in human placenta.
Ozdemir
Yüksel
Y
Department of Physics, Ataturk University School of Arts and Sciences, Erzurum, Turkey. yozdemir25@yahoo.com
Börekci
Bünyamin
B
Levet
Aytaç
A
Kurudirek
Murat
M
D000328:Adult; D001724:Birth Weight; D003300:Copper / Q000378:metabolism; D005260:Female; D005453:Fluorescence; D006801:Humans; D007231:Infant, Newborn; D007501:Iron / Q000378:metabolism; D008423:Maternal Age; D010920:Placenta / Q000737:chemistry / Q000378:metabolism*; D011247:Pregnancy; D013052:Spectrometry, X-Ray Emission; D014131:Trace Elements / Q000032:analysis* / Q000378:metabolism; D015032:Zinc / Q000378:metabolism
D014131:Trace Elements; D003300:Copper; D007501:Iron; D015032:Zinc