DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise.
We present herein transcriptional changes in mouse spinal cords in response to physical exercise on a treadmill using a DNA microarray. By 30-min exercise, the expression of 3 genes was enhanced and expression of 29 genes reduced. By continuous 2-week exercise (30-min exercise per day), the expression of 1 gene was enhanced and expression of 13 genes reduced.
Hashimoto
Kazunori
K
Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Honda
Akiko
A
Hayashi
Yuichi
Y
Inuzuka
Takashi
T
Satoh
Masahiko
M
Hozumi
Isao
I
D000690:Amyotrophic Lateral Sclerosis / Q000209:etiology / Q000628:therapy; D000818:Animals; D018076:DNA, Complementary; D004195:Disease Models, Animal; D015870:Gene Expression; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D020411:Oligonucleotide Array Sequence Analysis; D010805:Physical Conditioning, Animal / Q000502:physiology*; D012313:RNA / Q000302:isolation & purification; D013116:Spinal Cord / Q000378:metabolism*; D014158:Transcription, Genetic
D018076:DNA, Complementary; D012313:RNA