title: [Catastrophic antiphospholipid syndrome complicated by cardiogenic shock - a case report].
abstract: A case of a 29-year-old woman 18 days after delivery with catastrophic antiphospholipid syndrome secondary (CAPS) due to undiagnosed systemic lupus erythematosus, leading to cardiogenic shock is reported. Laboratory evaluation revealed increased anticardiolipin antibodies, lupus anticoagulant, antinuclear antibody and thrombocytopenia. Left ventricular ejection fraction was 20%, neurologic deficit and acute renal failure were also present. Cardiac involvement is common in CAPS, but cardiomyopathy due to microvascular thrombosis is rare. CAPS should be considered as a cause of acute heart failure in a women with systemic lupus erythematosus. In the presented case early therapy with anticoagulants, steroids, immunoglobulins and plasmaferesis was beneficial.
authors: I Katedra i Klinika Kardiologii, Gdański Uniwersytet Medyczny. awegrzyn@amg.gda.pl
authors: Bozena
authors: B
authors: Zieba
authors: Agnieszka
authors: A
authors: Wegrzyn
authors: Andrzej
authors: A
authors: Mital
authors: Maria
authors: M
authors: Szczepińska-Nowak
authors: Lukasz
authors: L
authors: Lewicki
authors: Michał
authors: M
authors: Chmielecki
authors: Wiesław
authors: W
authors: Puchalski
authors: Andrzej
authors: A
authors: Rynkiewicz
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D012770:Shock, Cardiogenic / Q000150:complications* / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome