title: Population data for Y-chromosome haplotypes defined by AmpFlSTR YFiler PCR amplification kit in North Sardinia (Italy).
abstract: The 17 Y-chromosomal short tandem repeats (STRs) included in the AmpFlSTR YFiler Amplification Kit (AB Applied Biosystems) (DYS19, DYS3891, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATA H4.1) were typed in 100 samples from North Sardinia (Italy). A total of 91 different haplotypes were found, where 9 haplotypes were shared by two individuals. The overall haplotype diversity (HD) was 0.9982. DYS458 non-consensus alleles were found in one samples, and one in the DYS438. We found a double peak in one sample for the DYS19 with alleles 15/16. Population comparisons with available 10 YSTR loci data in Mediterranean Basin samples were undertaken, significant differences were observed between our sample and all the compared populations, except for a entire sample from Sardinia. Prediction of haplogroups showed I2al was found to be the most frequent haplogroup (33%) in our sample. Testing high-resolution Y-chromosome data sets it is useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.
authors: Section of Anthropology, Department of Experimental Biology, University of Cagliari, Monserrato-Cagliari, Italy. meghiani@unica.it
authors: Maria Elena
authors: ME
authors: Ghiani
authors: Alessandro
authors: A
authors: Mameli
authors: Gavino
authors: G
authors: Piras
authors: Andrea
authors: A
authors: Berti
authors: Carla Maria
authors: CM
authors: Calo
authors: Giuseppe
authors: G
authors: Vona
mesh_terms: D041322:Chromosomes, Human, Y / Q000235:genetics*; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population / Q000379:methods*; D006239:Haplotypes; D006801:Humans; D007558:Italy; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*
chemical_list: D005819:Genetic Markers