Dissecting the phenotype in genome-wide association studies of psychiatric illness.
Over the past 2 years genome-wide association studies have made major contributions to understanding the genetic architecture of many common human diseases. This editorial outlines the development of such studies in psychiatry and highlights the opportunities for advancing understanding of the biological underpinnings and nosological structure of psychiatric disorders.
Craddock
Nick
N
Kendler
Kenneth
K
Neale
Michael
M
Nurnberger
John
J
Purcell
Shaun
S
Rietschel
Marcella
M
Perlis
Roy
R
Santangelo
Susan L
SL
Schulze
Thomas G
TG
Schulze
Thomas
T
Smoller
Jordan W
JW
Thapar
Anita
A
D000328:Adult; D055106:Genome-Wide Association Study; D006801:Humans; D001523:Mental Disorders / Q000235:genetics*; D010641:Phenotype