title: Point mutation rate of bacteriophage PhiX174.
abstract: The point mutation rate of phage PhiX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0x10(-6) substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per round of copying in DNA-based microorganisms).
authors: Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departamento de Genética, Universitat de València, 46071 València, Spain.
authors: José M
authors: JM
authors: Cuevas
authors: Siobain
authors: S
authors: Duffy
authors: Rafael
authors: R
authors: Sanjuán
mesh_terms: D010584:Bacteriophage phi X 174 / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics; D004926:Escherichia coli / Q000821:virology; D016679:Genome, Viral / Q000235:genetics; D017354:Point Mutation
chemical_list: D004279:DNA, Viral