Emerging concepts in airway infantile hemangioma assessment and management.
OBJECTIVE
The purpose of this study was to evaluate changes in airway infantile hemangioma treatment.


METHODS
Retrospective.


METHODS
Airway hemangioma patients, tertiary pediatric hospital.


METHODS
Data collected included age at diagnosis, evaluation methods, hospitalizations, airway size, and interventions. Patients were divided into group A (1981-1993) and group B (1994-2005) and were analyzed using descriptive statistics, the Fisher exact test, and the Student t test.


RESULTS
Thirty-two subjects were identified. Nasopharyngoscopy was used more in group B (11/16 [69%]) than group A (4/16 [25%], P=0.032). CT angiography (3/16 [19%]) and laryngeal distractors (11/16 [69%]) were only used in group B; these techniques showed airway hemangiomas to be "transglottic," not just "subglottic." Intralesional steroids alone (3/16 [19%]) and primary hemangioma excision (2/16 [13%]) were new treatments used in group B. Frequent direct laryngoscopies (>six) correlated with tracheotomy (5/32 [16%], P=0.015). Presenting age (<2 months) impacted treatment more than airway hemangioma size.


CONCLUSIONS
New methods of airway infantile hemangioma assessment changed our concept of airway hemangiomas and their primary treatment.
Perkins
Jonathan A
JA
Division of Pediatric Otolaryngology and Department of Otolaryngology-Head and Neck Surgery, Seattle Children's Hospital, Seattle, WA 98105-0371, USA. jonathan.perkins@seattlechildrens.org
Duke
William
W
Chen
Eunice
E
Manning
Scott
S
D005260:Female; D005931:Glottis / Q000601:surgery; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006391:Hemangioma / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D007828:Laryngoscopy / Q000379:methods*; D008297:Male; D008499:Medical Records; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome
D005938:Glucocorticoids