title: Chronic inflammatory and non-inflammatory diseases of the gastrointestinal tract in cats: diagnostic advantages of full-thickness intestinal and extraintestinal biopsies.
abstract: An evaluation of histological findings in full-thickness biopsies from the gastrointestinal tract (GIT) and extraintestinal samples of 43 cats with chronic GIT disease signs was performed. In the majority of cases (46.5%) inflammatory bowel disease, ie, lymphocytic-plasmacytic enteritis/colitis (32.6%), eosinophilic gastroenterocolitis (11.6%) and mixed inflammatory infiltration (2.3%), was diagnosed. Furthermore, in four animals non-inflammatory mucosal band-shaped fibrosis (9.3%), and in 10 cats (23.3%) a diffuse lymphoma, was found. Six cats displayed only a gastritis (7.0%) or lymphangiectasia (7.0%), respectively. In two cats a mast cell tumour (4.7%) was diagnosed. In one cat no histopathological lesions were found. The availability of transmural biopsies from all segments of the intestine and the collection of extraintestinal samples, especially mesenteric lymph nodes, is especially helpful for diagnosing intestinal tumours such as lymphomas and tumours of mast cell origin.
authors: Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg 17, D-30559 Hannover, Germany.
authors: Sven
authors: S
authors: Kleinschmidt
authors: Jasmine
authors: J
authors: Harder
authors: Ingo
authors: I
authors: Nolte
authors: Sina
authors: S
authors: Marsilio
authors: Marion
authors: M
authors: Hewicker-Trautwein
mesh_terms: D000818:Animals; D001706:Biopsy / Q000379:methods / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis / Q000473:pathology*; D002415:Cats; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D007422:Intestines / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010179:Pancreas / Q000473:pathology; D012189:Retrospective Studies