Choroidal folds in acute Vogt-Koyanagi-Harada disease.
OBJECTIVE
To shed light on the clinical significance of choroidal folds (CFs) in acute Vogt-Koyanagi-Harada disease (VKH).


METHODS
Twenty-three acute uveitic VKH patients diagnosed between October 2001 and January 2008 were reviewed retrospectively.


RESULTS
Twelve (52%) patients had CFs; for patients with CFs, more had poor initial visual acuity (<or= 0.1 in either eye, p <.05), and more received immunomodulatory therapy (IMT) than those without CFs (p <.05). Patients without CFs had better best-corrected visual acuity (BCV) at final visit (p <.01).


CONCLUSIONS
CFs are probably a sign of severe choroidal inflammation and associated with corticosteroid resistance and/or dependence, which indicates IMT.
Zhao
Chan
C
Ophthalmology Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhang
Meifen
M
Wen
Xin
X
Dong
Fangtian
F
Han
Baoling
B
Du
Hong
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D015862:Choroid Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000188:drug therapy; D014792:Visual Acuity; D055815:Young Adult
D004396:Coloring Agents; D007155:Immunologic Factors; D007208:Indocyanine Green