title: Cystic fibrosis, common variable immunodeficiency and Aspergers syndrome: an immunological and behavioural challenge.
abstract: BACKGROUND
  Cystic fibrosis (CF) is of particular importance in Ireland as the Irish population has both the highest incidence (2.98/10,000) and the highest carrier rate (1 in 19) in the world. Primary immunodeficiency has not been previously reported as co-existing with CF.
  
  
  METHODS
  We report a unique case of CF associated with a primary immunodeficiency syndrome--common variable immunodeficiency (CVID).
  
  
  CONCLUSIONS
  Our patient has CF, CVID and the additional comorbidity of Aspergers syndrome. The challenges inherent in diagnosing and treating such a case are outlined herein and the successful management of this case is evidenced by the well-preserved lung function of our patient.
authors: Respiratory Research Division, Department of Medicine, Education and Research Centre, Royal College of Surgeons in Ireland, Beaumont Hospital, Beaumont Road, Dublin 9, Republic of Ireland. schotirmall@rcsi.ie
authors: S H
authors: SH
authors: Chotirmall
authors: T B
authors: TB
authors: Low
authors: T
authors: T
authors: Hassan
authors: P
authors: P
authors: Branagan
authors: C
authors: C
authors: Kernekamp
authors: M G
authors: MG
authors: Flynn
authors: C
authors: C
authors: Gunaratnam
authors: N G
authors: NG
authors: McElvaney
mesh_terms: D000328:Adult; D020817:Asperger Syndrome / Q000150:complications* / Q000523:psychology; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000175:diagnosis; D003550:Cystic Fibrosis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology; D055815:Young Adult