The validity, reliability and clinical utility of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease.
OBJECTIVE
To evaluate the psychometric properties of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease (SVD).


METHODS
40 SVD patients and 40 matched controls were recruited. Concurrent and criterion validity, inter-rater and test-retest reliability, internal consistency of the HK-MoCA were examined and clinical observations were made.


RESULTS
Performance on the HK-MoCA was significantly predicted by both executive (beta = 0.23, p = 0.013) and non-executive (beta = 0.64, p < 0.001) composite scores. It differentiated SVD patients from controls (area under the curve = 0.81, p < 0.001) with an optimal cutoff at 21/22. Reliability, internal consistency and clinical utility were good.


CONCLUSIONS
The HK-MoCA is a useful cognitive screening instrument for use in SVD patients.
Wong
Adrian
A
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Xiong
Yun Y
YY
Kwan
Pauline W L
PW
Chan
Anne Y Y
AY
Lam
Wynnie W M
WW
Wang
Ki
K
Chu
Winnie C W
WC
Nyenhuis
David L
DL
Nasreddine
Ziad
Z
Wong
Lawrence K S
LK
Mok
Vincent C T
VC
D000368:Aged; D000375:Aging / Q000523:psychology; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000523:psychology*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology*; D003469:Culture; D004493:Education; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D015203:Reproducibility of Results; D012727:Sex Characteristics