Four tetracyclic oxindole alkaloids and a taberpsychine derivative from a Malayan Tabernaemontana.
Four tetracyclic oxindole alkaloids, 7(R)- and 7(S)-geissoschizol oxindole (1 and 2), 7(R),16(R)- and 7(S),16(R)-19(E)-isositsirikine oxindole (3 and 4), in addition to a taberpsychine derivative, N(4)-demethyltaberpsychine (5), were isolated from the Malayan Tabernaemontana corymbosa and the structures were established using NMR and MS analysis.
Lim
Kuan-Hon
KH
Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Sim
Kooi-Mow
KM
Department of Chemical Science, Faculty of Science, Engineering and Technology, Universiti Tunku Abdul Rahman, Jalan Universiti, Bandar Barat, 31900 Kampar, Perak, Malaysia.
Tan
Guan-Huat
GH
Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Kam
Toh-Seok
TS
Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: tskam@um.edu.my.
D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification; D008296:Malaysia; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D000078183:Oxindoles; D013237:Stereoisomerism; D030014:Tabernaemontana / Q000737:chemistry*
D026121:Indole Alkaloids; D007211:Indoles; C543073:N(4)-demethyltaberpsychine; D000078183:Oxindoles; C022960:2-oxindole