Transgenic primate research paves the path to a better animal model: are we a step closer to curing inherited human genetic disorders?
While the advancement of transgenic primate models has led to a new era in modeling human conditions and has a clear impact on elucidating the mechanism of human genetic diseases, some thoughts should be considered if non-human primates are the appropriate model.
Chan
Anthony W S
AW
Yerkes National Primate Research Center, Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30329, USA. awchan@emory.edu
D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics*; D004195:Disease Models, Animal; D030342:Genetic Diseases, Inborn / Q000628:therapy*; D036281:Genetic Research; D015894:Genome, Human / Q000235:genetics; D006801:Humans; D011323:Primates / Q000235:genetics*