Laparoscopy in gynecologic surgery: adhesion development, prevention, and use of adjunctive therapies.
Laparoscopic surgery has several proven advantages over open surgery. However, the role of laparoscopy in adhesion development and applicability of adhesion barrier is unclear. Adhesions occur in majority of women undergoing major laparoscopic gynecologic surgery and its sequel, are associated with significant morbidity, economic, and medico-legal consequences. Microsurgical principles and technique alone are insufficient to prevent adhesion formation. However, several biases limit the ability to compare different types of adhesion prevention products for efficacy. It is hoped that better understanding of pathways and demonstration of the mechanisms involved in adhesions formation may help in future research into this field.
Awonuga
Awoniyi O
AO
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Wayne State University, 3800 Woodward Avenue, Detroit, MI, USA.
Saed
Ghassan M
GM
Diamond
Michael P
MP
D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects / Q000379:methods; D006801:Humans; D008866:Microsurgery; D011183:Postoperative Complications / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic; D000267:Tissue Adhesions / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control