Omeprazole inhibits IL-4 and IL-13 signaling signal transducer and activator of transcription 6 activation and reduces lung inflammation in murine asthma.
Cortes
Jose R
JR
Rivas
Maria D
MD
Molina-Infante
Javier
J
Gonzalez-Nuñez
Maria A
MA
Perez-G
Moises
M
Masa
Juan F
JF
Sanchez
Juan F
JF
Zamorano
Jose
J
D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000008:administration & dosage; D000818:Animals; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology; D045744:Cell Line, Tumor; D004195:Disease Models, Animal; D018793:Interleukin-13 / Q000037:antagonists & inhibitors; D015847:Interleukin-4 / Q000037:antagonists & inhibitors*; D051379:Mice; D009853:Omeprazole / Q000008:administration & dosage*; D000077402:Pantoprazole; D010766:Phosphorylation / Q000187:drug effects; D011014:Pneumonia / Q000188:drug therapy* / Q000276:immunology; D054328:Proton Pump Inhibitors / Q000008:administration & dosage*; D050800:STAT6 Transcription Factor / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects / Q000276:immunology
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D018793:Interleukin-13; D054328:Proton Pump Inhibitors; D050800:STAT6 Transcription Factor; C494100:Stat6 protein, mouse; D015847:Interleukin-4; D000077402:Pantoprazole; D009853:Omeprazole