title: Is there a role for triclosan/copolymer toothpaste in the management of periodontal disease?
abstract: Dental caries and periodontal disease are the most common oral conditions experienced by adults today. The treatment of these diseases by the dental team can only be performed when patients attend dental practices. There is recognition that the preventive measures patients perform at home between dental visits is of vital importance in the control of these diseases. Water fluoridation and fluoridated toothpastes have made enormous progress into the prevention of dental caries worldwide. However, prevention of periodontal disease is yet to enjoy the same success. A number of toothpastes have been developed for the prevention and control of periodontal disease. One such toothpaste - containing triclosan/copolymer - has been thoroughly researched. The literature pertaining to the efficacy, mode of action and safety of triclosan/copolymer toothpaste has been reviewed. A MEDLINE search identified 198 articles dated from 1989 to 2008. The findings of this body of research are discussed and conclusions regarding the efficacy of triclosan/copolymer toothpaste in the home-care management of periodontal disease are presented.
authors: Faculty of Dentistry, The University of Sydney, Westmead, NSW 2145, Australia. a.blinkhorn@usyd.edu.au
authors: Anthony
authors: A
authors: Blinkhorn
authors: P M
authors: PM
authors: Bartold
authors: M P
authors: MP
authors: Cullinan
authors: T E
authors: TE
authors: Madden
authors: R I
authors: RI
authors: Marshall
authors: S L
authors: SL
authors: Raphael
authors: G J
authors: GJ
authors: Seymour
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D003773:Dental Plaque / Q000517:prevention & control; D005891:Gingivitis / Q000517:prevention & control; D006801:Humans; D008298:Maleates; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000517:prevention & control*; D010518:Periodontitis / Q000517:prevention & control; D014677:Pharmaceutical Vehicles; D011095:Polyethylenes; D012449:Safety; D014100:Toothpastes / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014260:Triclosan / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000891:Anti-Infective Agents, Local; D003692:Delayed-Action Preparations; D008298:Maleates; D014677:Pharmaceutical Vehicles; D011095:Polyethylenes; D014100:Toothpastes; D014260:Triclosan; C043105:poly(methyl vinyl ether-co-maleic anhydride)