title: [Whooping cough in an urban high school in Hungary. Conclusions of a local pertussis outbreak].
abstract: Although incidence of pertussis has been gradually decreased with the introduction of active immunization, total eradication is not possible. This has been shown by national and international data, as well. In the early 2000's, slow increase in incidence of pertussis was observed.
  
  
  OBJECTIVE
  To demonstrate the presence of Bordetella pertussis in the Hungarian population by presenting 17 cases of adolescent pertussis.
  
  
  METHODS
  Etiology of pertussis was confirmed by quantification of pertussis-antibodies in blood samples taken from permanently coughing patients in the firstly identified subject's vicinity which latter was explored by retrospective data collection.
  
  
  RESULTS
  In the vicinity of the first identified patient epidemiologic research identified another 16 patients all of which were confirmed by serological tests.
  
  
  CONCLUSIONS
  If permanent coughing is present, pertussis needs to be ruled out. Immunity against pertussis obtained by vaccination fades by the end of childhood. Bordetella pertussis circulates in the national population. A booster-vaccination against pertussis in the regular vaccination course for the 11-year old children is recommended. Pertussis in adolescents and in adults is mild and atypical, but in case of prolonged coughing it needs to be considered.
authors: Vas Megyei Markusovszky Kórház Nonprofit Zrt., Infektológiai Osztály, Szombathely. schneider.ferenc@markusovszky.hu
authors: Ferenc
authors: F
authors: Schneider
authors: Eva
authors: E
authors: Stánitz
authors: Judit
authors: J
authors: Kalácska
authors: Tünde
authors: T
authors: Tompity
authors: Beáta
authors: B
authors: Gábor
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood; D001886:Bordetella pertussis / Q000276:immunology; D002648:Child; D004196:Disease Outbreaks / Q000517:prevention & control; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007117:Immunization, Secondary; D015994:Incidence; D008297:Male; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D012574:Schools; D014917:Whooping Cough / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*
chemical_list: D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine