title: 19alpha-Hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum.
abstract: A bioactivity guided fractionation of roots of Canthium multiflorum led to the isolation of the new ursenoic acid derivative 19alpha-hydroxy-3-oxo-ursa-1,12-dien-28-oic acid (1), which showed antiplasmodial effect without inducing change of the shape of membranes of erythrocytes.
authors: Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors: Maminata
authors: M
authors: Traoré-Coulibaly
authors: Hanne L
authors: HL
authors: Ziegler
authors: Carl Erik
authors: CE
authors: Olsen
authors: Millogo-kone
authors: MK
authors: Hassanata
authors: Guissou I
authors: GI
authors: Pierre
authors: Odile G
authors: OG
authors: Nacoulma
authors: T Rober
authors: TR
authors: Guiguemdé
authors: S Brøgger
authors: SB
authors: Christensen
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010963:Plasmodium falciparum / Q000187:drug effects*; D019666:Rubiaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D000962:Antimalarials; D014315:Triterpenes