title: Echocardiography to magnetic resonance image registration for use in image-guided cardiac catheterization procedures.
abstract: We present a robust method to register three-dimensional echocardiography (echo) images to magnetic resonance images (MRI) based on anatomical features, which is designed to be used in the registration pipeline for overlaying MRI-derived roadmaps onto two-dimensional live x-ray images during cardiac catheterization procedures. The features used in image registration are the endocardial surface of the left ventricle and the centre line of the descending aorta. The MR-derived left ventricle surface is generated using a fully automated algorithm, and the echo-derived left ventricle surface is produced using a semi-automatic segmentation method provided by the QLab software (Philips Healthcare) that it is routinely used in clinical practice. We test our method on data from six volunteers and four patients. We validated registration accuracy using two methods: the first calculated a root mean square distance error using expert identified anatomical landmarks, and the second method used catheters as landmarks in two clinical electrophysiology procedures. Results show a mean error of 4.1 mm, which is acceptable for our clinical application, and no failed registrations were observed. In addition, our algorithm works on clinical data, is fast and only requires a small amount of manual input, and so it is applicable for use during cardiac catheterization procedures.
authors: Division of Imaging Sciences, King's College, London SE1 7EH, UK. y.ma@kcl.ac.uk
authors: Ying Liang
authors: YL
authors: Ma
authors: Graeme P
authors: GP
authors: Penney
authors: C Aldo
authors: CA
authors: Rinaldi
authors: Mike
authors: M
authors: Cooklin
authors: Reza
authors: R
authors: Razavi
authors: Kawal S
authors: KS
authors: Rhode
mesh_terms: D000465:Algorithms; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery; D006328:Cardiac Catheterization / Q000379:methods*; D016022:Case-Control Studies; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted / Q000379:methods*