[Molecular basis of photoaging].
As a result of the increase in life expectancy, the study of the organic process of aging has been stimulated. Skin ageing, which reflects the signs of time, is a time-dependent process of progressive deterioration that can be intensified by sun exposure, which is known as photoaging. The damage of radiation on various cell structures and on the skin results in molecular and morphological changes to these components. Many research studies are performed to try to minimize the effects of photoaging; however, the main strategy to manage it is still prevention, which will only be achieved once we learn about the mechanisms involved in the process.
Montagner
Suelen
S
Hospital Municipal Dr Mário Gatti, Campinas, SP, Brazil. suelen_montagner@yahoo.com.br
Costa
Adilson
A
D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics; D006801:Humans; D009154:Mutation / Q000235:genetics; D011743:Pyrimidines / Q000737:chemistry / Q000528:radiation effects; D037761:Sirtuins / Q000235:genetics / Q000528:radiation effects; D015595:Skin Aging / Q000502:physiology / Q000528:radiation effects*; D013473:Sunscreening Agents; D014466:Ultraviolet Rays / Q000009:adverse effects*
D004272:DNA, Mitochondrial; D011743:Pyrimidines; D013473:Sunscreening Agents; D037761:Sirtuins