title: Inflammatory epidermolysis bullosa acquisita mimicking toxic epidermal necrolysis and dermatitis herpetiformis.
abstract: We report a patient with a spectrum of clinical features simulating toxic epidermal necrolysis, bullous erythema multiforme and later, dermatitis herpetiformis (DH). The histological features were suggestive of DH, bullous pemphigoid (BP) and epidermolysis bullosa acquisita (EBA). Direct immunofluorescence results suggested BP or EBA. Indirect immunofluorescence on salt-split skin and immunoblotting analysis on normal human dermal extracts gave results that were diagnostic for EBA.
authors: Dermatology Centre, Salford Royal Hospital NHS Foundation Trust, Salford, Manchester, UK. vishalmadan@doctors.org.uk
authors: V
authors: V
authors: Madan
authors: L A
authors: LA
authors: Jamieson
authors: B S
authors: BS
authors: Bhogal
authors: C S
authors: CS
authors: Wong
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000378:metabolism; D003874:Dermatitis Herpetiformis / Q000188:drug therapy / Q000473:pathology*; D003937:Diagnosis, Differential; D016107:Epidermolysis Bullosa Acquisita / Q000188:drug therapy / Q000473:pathology*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D008297:Male; D013262:Stevens-Johnson Syndrome / Q000188:drug therapy / Q000473:pathology*
chemical_list: D001323:Autoantibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G