Polyethylene glycol-modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency.
Somech
Raz
R
Lai
Yew Hon
YH
Grunebaum
Eyal
E
Le Saux
Nicole
N
Cutz
Ernest
E
Roifman
Chaim M
CM
D000243:Adenosine Deaminase / Q000172:deficiency* / Q000627:therapeutic use; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism; D005500:Follow-Up Studies; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007231:Infant, Newborn; D008107:Liver Diseases / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology; D008171:Lung Diseases / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology; D008214:Lymphocytes / Q000201:enzymology / Q000378:metabolism; D008297:Male; D016511:Severe Combined Immunodeficiency / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology
D007136:Immunoglobulins; D000243:Adenosine Deaminase; C051409:pegademase bovine