Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg.
OBJECTIVE
To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher.


METHODS
Prospective, randomized clinical trial.


METHODS
Twenty-eight patients.


METHODS
Patients had received no prior medical glaucoma treatment. Routine ophthalmic examinations and visual field tests were performed before and after treatment for each patient.


RESULTS
Mean IOP was 32.28 +/- 0.92 mmHg before treatment. Mean IOP levels were 18.75 +/- 0.68 for the first day, 17.96 +/- 0.90 for the first week and 17.64 +/- 0.66 for the first month after treatment.


CONCLUSIONS
A fixed combination of latanoprost 0.005% and timolol 0.5% is effective in significantly reducing IOP in glaucoma patients with an IOP greater than 30 mmHg.
Ozkurt
Yelda Buyru
YB
Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Sengor
Tomris
T
Evciman
Tufan
T
Haboğlu
Melih
M
Baş
Gökçen
G
Aydin
Sevda
S