title: [Morphological changes of experimentally modelled pararectal fistula after application of the thrombofibrin gel].
abstract: Pararectal fistulas is the most frequently revealed proctological pathology, their rate constitutes 0.5-4% in the rectal diseases structure. We have proposed a new method of treatment of complex pararectal fistulas, using fibrin-gel, the procedure is simple and miniinvasive. In experiment on rabbits the artificial pararectal fistula was formed. Morphological changes under the influence of treatment were studied up on the 3rd, 7th and 10th days. While application of fibrin-gel the acceleration of epithelial cells and fistula channels regeneration was noted.
authors: G A
authors: GA
authors: Sultanov
authors: A K
authors: AK
authors: Safieva
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011817:Rabbits; D012003:Rectal Fistula / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D012007:Rectum / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive