title: Intranasal corticosteroids: do they improve ocular allergy?
abstract: Allergic rhinoconjunctivitis (ARC) is a commonallergic condition associated with high financial costs and decreased quality of life. Medical treatment options are extensive and include oral, ophthalmic, and intranasal agents. Intranasal corticosteroids (INS) have traditionally been used for chronic management of nasal symptoms, but have also demonstrated an impact on decreasing ocular symptoms of itching, tearing, and redness. Study design, including the method and timing of scoring ocular symptoms, is an important factor affecting whether changes in ocular symptoms are detected in INS clinical trials. INS are thought to exert their influence on the eye through the naso-ocular reflex, and to date their impact on ocular symptoms appears to be a class effect.
authors: Division of Allergy, Immunology and Rheumatology, UMDNJ, New Jersey Medical School, Springfield, NJ 07081, USA.
authors: Catherine
authors: C
authors: Origlieri
authors: Leonard
authors: L
authors: Bielory
mesh_terms: D000281:Administration, Intranasal; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003233:Conjunctivitis, Allergic / Q000188:drug therapy* / Q000453:epidemiology / Q000276:immunology; D005123:Eye / Q000187:drug effects* / Q000276:immunology; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000453:epidemiology / Q000276:immunology
chemical_list: D000305:Adrenal Cortex Hormones; D018926:Anti-Allergic Agents; D006633:Histamine Antagonists