(2-Pyridyl)acetone-promoted Cu-catalyzed O-arylation of phenols with aryl iodides, bromides, and chlorides.
Employing (2-pyridyl)acetone as a new supporting ligand, the copper-catalyzed coupling reactions of aryl chlorides, aryl bromides, and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. This reaction displays great functional groups compatibility and excellent reactive selectivity.
Zhang
Qi
Q
Jiangsu Provincial Institute of Materia Medica, Nanjing University of Technology, Nanjing, China.
Wang
Deping
D
Wang
Xianyang
X
Ding
Ke
K
D000096:Acetone / Q000031:analogs & derivatives / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D008956:Models, Chemical; D010636:Phenols / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
D006842:Hydrocarbons, Brominated; D006843:Hydrocarbons, Chlorinated; D006847:Hydrocarbons, Iodinated; D010636:Phenols; D011725:Pyridines; D000096:Acetone; D003300:Copper; C023666:pyridine