title: Neurological symptoms in children with intussusception.
abstract: OBJECTIVE
  The classical combination of abdominal pain, vomiting, rectal blood loss and a palpable abdominal mass is only present in a minority of children with intussusception. Neurological signs and symptoms have been described, but are not a well understood phenomenon. We performed a retrospective study to ascertain the frequency and nature of these symptoms and to describe the characteristics of the patients presenting in this atypical way.
  
  
  METHODS
  The records of 58 children presenting with intussusception from 2003 to 2008 were reviewed for abdominal and neurological signs and symptoms, duration of symptoms and effectiveness of treatment.
  
  
  RESULTS
  In 10 out of 58 patients (17%), one or more neurological symptoms were recorded at presentation, with lethargy being the most frequent, followed by hypotonia and fluctuating consciousness. The patients with neurological abnormalities were significantly younger and presented with a shorter duration of symptoms. Therapy was more invasive, although not statistically significant, in this patient category.
  
  
  CONCLUSIONS
  Intussusception should be considered in the differential diagnosis in young children presenting with lethargy, hypotonia and/or sudden alterations of consciousness even in the absence of the classical symptoms of intussusception.
authors: Department of Paediatrics, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands. k.kleizen@cukz.umcn.nl
authors: K J
authors: KJ
authors: Kleizen
authors: A
authors: A
authors: Hunck
authors: M H
authors: MH
authors: Wijnen
authors: J M Th
authors: JM
authors: Draaisma
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007443:Intussusception / Q000150:complications / Q000175:diagnosis*; D053609:Lethargy / Q000209:etiology; D008297:Male; D009123:Muscle Hypotonia / Q000209:etiology; D012189:Retrospective Studies; D014474:Unconsciousness / Q000209:etiology