title: Chemical composition, allelopatic and cytotoxic effects of essential oils of flowering tops and leaves of Crambe orientalis L. from Iran.
abstract: Crambe orientalis L. (Brassicaceae), a perennial herb, is indigenous to Iran. The essential oils of flowering tops and leaves of the plant were evaluated by GC-MS. Our results showed that while 2-methyl-5-hexenitrile (19.5%) and benzyl cyanide (16.9%) were the major components of flowering tops oil, the oil of the leaves was dominated by octyl-acetate (54.3%) and butenyl-4-isothiocyanates (22.6%). The oils exhibited modest allelopatic effects on lettuce. The leaf oil showed high-cytotoxic effects against Mc-Coy cell lines, with an RC(50) value of 16 microg mL(-1).
authors: Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran. razavi694@gmail.com
authors: Seyed Mehdi
authors: SM
authors: Razavi
authors: Samad
authors: S
authors: Nejad-Ebrahimi
mesh_terms: D000818:Animals; D019607:Brassicaceae / Q000737:chemistry*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D035263:Flowering Tops / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D018525:Germination / Q000187:drug effects; D006801:Humans; D007492:Iran; D018545:Lactuca / Q000187:drug effects / Q000502:physiology; D051379:Mice; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity*; D018515:Plant Leaves / Q000737:chemistry*; D012639:Seeds / Q000187:drug effects
chemical_list: D009822:Oils, Volatile