Reaction information management - a perspective.
Structure-based reaction information management systems have been available to synthetic chemists for 30 years. The initial synthesis planning systems were supplemented 10 years later by reaction retrieval programs. After a short summary of the development of these systems, the reasons for the present underutilization of reaction retrieval programs and recent developments to improve the situation will be discussed. This paper will provide some suggestions for required future improvements, particularly in view of the availability of increasingly large databases.
Grethe
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MDL Information Systems Inc, San Leandro, CA 94577, USA. guenter@mdli.com