title: Esophageal pressure method and impulse oscillometry to assess mechanical properties of the respiratory system in healthy men.
abstract: BACKGROUND
  Lung elasticity can be assessed by pulmonary compliance using the esophageal pressure method, but this technique is invasive and time-consuming. Impulse oscillometry has been established as a non-invasive method to describe mechanical properties of the respiratory system and preliminary data suggest that it may be used as a marker of lung elasticity. Therefore we compared impulse oscillometry and pulmonary compliance in healthy subjects.
  
  
  METHODS
  In 31 healthy male volunteers aged 20 to 25 years we performed pulmonary function tests including spirometry, bodyplethysmography and pulmonary compliance by the esophageal pressure method. Impulse oscillometry (IOS) was used to determine capacitance (X 5 Hz) and resistance (R 5 Hz and R 20 Hz).
  
  
  RESULTS
  Mean dynamic pulmonary compliance was 2.53+/-0.58 l/kPa and mean static pulmonary compliance was 2.82+/-0.85 l/kPa. R 5 Hz and R 20 Hz were between 0.14 and 0.49 kPa/(l/s), while mean X 5 Hz was -0.08+/-0.02 kPa/(l/s). There was demonstrated a highly significant correlation between impulse oscillometric capacitance X 5 Hz and pulmonary compliance parameters.
  
  
  CONCLUSIONS
  The results of the present study suggest that impulse oscillometry may be used as an alternative for the invasive esophageal pressure method in determining pulmonary elasticity.
authors: Bethanien Hospital Solingen, Clinic for Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute for Pneumology at the University Witten/Herdecke, Solingen, Germany. galetke@klinik-bethanien.de
authors: Wolfgang
authors: W
authors: Galetke
authors: Winfried J
authors: WJ
authors: Randerath
authors: Christine
authors: C
authors: Feier
authors: Thomas
authors: T
authors: Muth
authors: Elisabeth
authors: E
authors: Borsch-Galetke
mesh_terms: D000328:Adult; D000886:Anthropometry; D025802:Electric Capacitance; D004947:Esophagus / Q000502:physiology*; D006262:Health; D006801:Humans; D008170:Lung Compliance; D008297:Male; D009991:Oscillometry / Q000379:methods*; D011312:Pressure; D012016:Reference Values; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics / Q000502:physiology*