title: Intravenous peripherally-inserted central catheters for antibiotic therapy in children with cystic fibrosis.
abstract: BACKGROUND
  We aimed to evaluate the use of central catheters introduced by a peripheral vein (PICC) in children with CF.
  
  
  METHODS
  A descriptive study in patients in whom a PICC (Beckton Dickinson) was inserted.
  
  
  RESULTS
  24 children aged (median (range) 10.2 years (0.3-17.3) undergoing 44 procedures were included. PICC was successfully inserted in 93.2% (41/44) of cases. Total procedure duration was (median (range)) 32.5 (10-105) minutes. The operators encountered few difficulties, median (range) 2 (1-10) (1 (absence) to 10 (maximal)); median (range) 1 (1 to 5) attempt per child). No major side effects or infections were observed. PICC obstruction in 5 (12%) cases was successfully unblocked in 4 cases (urokinase). The catheter was functional throughout the antibiotic course in 40/41 cases. A final Doppler scan (30 cases) showed total permeability of the central veins in all cases. Satisfaction index of the operators and the patients were high: median (range) 9.5 (1-10) and 8.0 (6-10) (scale: 1 (worse) to 10 (best)), respectively.
  
  
  CONCLUSIONS
  PICCs are simple to use, and may be safely inserted in the ward. Such catheters are well tolerated, may increase the well-being of children with CF and prove an effective means by which to deliver IV therapy in this population.
authors: CHU de Bordeaux, Hôpital Pellegrin-Enfants, CRCM Pédiatrique, France. stephanie.bui@chu-bordeaux.fr
authors: S
authors: S
authors: Bui
authors: F
authors: F
authors: Babre
authors: S
authors: S
authors: Hauchecorne
authors: N
authors: N
authors: Christoflour
authors: F
authors: F
authors: Ceccato
authors: V
authors: V
authors: Boisserie-Lacroix
authors: H
authors: H
authors: Clouzeau
authors: M
authors: M
authors: Fayon
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002405:Catheterization, Central Venous / Q000379:methods*; D002406:Catheterization, Peripheral; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents