Fungal keratitis with intracameral extension following penetrating keratoplasty.
OBJECTIVE
To report the clinical findings and management of a case of fungal keratitis with extension into the anterior chamber following penetrating keratoplasty.


METHODS
Interventional case report.


RESULTS
A 45-year-old man developed a white, cottonball-like mass in the anterior chamber 3 months after penetrating keraplasty for keratoconus. Cytology evaluation was performed following excisional biopsy of the intracameral portion of the lesion. The presence of filamentous fungus was confirmed. The patient was treated with oral, topical, and intracameral voriconazole with complete resolution of the infection 9 months after initial presentation.


CONCLUSIONS
This case illustrates the unusual presentation of fungal keratitis with intracameral extension and demonstrates effective management with preservation of the corneal graft and restoration of visual function.
Gupta
Gaurav
G
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. gaurav_gupta@northwestern.edu
Feder
Robert S
RS
Lyon
Alice T
AT
D000284:Administration, Oral; D000287:Administration, Topical; D000867:Anterior Chamber / Q000473:pathology*; D000935:Antifungal Agents / Q000008:administration & dosage; D001228:Aspergillosis / Q000188:drug therapy / Q000209:etiology*; D003319:Corneal Stroma / Q000601:surgery; D003646:Debridement; D004334:Drug Administration Schedule; D006084:Graft Rejection / Q000188:drug therapy; D006801:Humans; D007267:Injections; D007634:Keratitis / Q000382:microbiology* / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D007640:Keratoconus / Q000601:surgery; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011239:Prednisolone / Q000008:administration & dosage; D011743:Pyrimidines / Q000008:administration & dosage; D014230:Triazoles / Q000008:administration & dosage; D014792:Visual Acuity; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D011239:Prednisolone; D065819:Voriconazole