Luteinizing hormone releasing hormone agonists and antagonists: current status.
Gonadotropin-releasing hormone and its analogs have opened up exciting new avenues of therapy in virtually every sub-specialty of internal medicine, including gynecology, pediatrics and urology. Since the discovery of GnRH in 1971, a number of agonists and antagonists have been synthesized and evaluated. This article sets out to review luteinizing hormone releasing hormone antagonists and agonists that are in preclinical and clinical stages of development or are on the market.
Petousis
N H
NH
Abbott Laboratories, CAPD, R13, 54Z, N Chicago, IL 60064-4000, USA. Nikolaos.Petousis@Abbott.com