title: Rationale, design, and profiles of the New Integrated Suburban Seniority Investigation (NISSIN) Project: a study of an age-specific, community-based cohort of Japanese elderly.
abstract: BACKGROUND
  Although there have been many studies on aging in a number of developed countries, data on the effects of aging during early senescence are scarce. We designed a study to investigate an age-specific cohort in a suburban Japanese city to determine the factors that contribute to living long and well.
  
  
  METHODS
  In every year from 1996 through 2005, residents of Nissin City, Japan who were about to reach the age of 65 years participated in health check-ups and completed a baseline self-administered questionnaire that included items on demographic and lifestyle characteristics, physical function, and quality of life. When the participants reached 70 years of age, they underwent secondary health check-ups at the same site, or received home visits from public health nurses, and their health-related outcomes were noted.
  
  
  RESULTS
  A total of 3073 64-year-olds were enrolled in the study (response rate, 43.9%). There was considerable intersexual variation in demographic and lifestyle factors. Among men and women, 24.3% and 3.0% were current smokers, respectively, and 68.7% and 19.5% were current alcohol drinkers. Cohort members were in slightly better physical condition than the Japanese general population: they were less likely to be obese and hypertensive and more likely to have 20 teeth or more. Follow-up of the cohort is ongoing.
  
  
  CONCLUSIONS
  We have established a unique age-specific cohort with a consecutive entry-exit system. This project should provide data on early changes in health and related factors in this new era of longevity.
authors: Kyoto University Health Service, Kyoto 606-8501, Japan.
authors: Tetsuhisa
authors: T
authors: Kitamura
authors: Takashi
authors: T
authors: Kawamura
authors: Akiko
authors: A
authors: Tamakoshi
authors: Kenji
authors: K
authors: Wakai
authors: Masahiko
authors: M
authors: Ando
authors: Yoshiyuki
authors: Y
authors: Ohno
mesh_terms: D000368:Aged; D015331:Cohort Studies; D055812:Community-Based Participatory Research; D005260:Female; D006304:Health Status; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008019:Life Style; D008136:Longevity; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012107:Research Design; D011795:Surveys and Questionnaires