Stem/progenitor cells: a potential source of retina-specific cells for retinal repair.
Retinal injury generally results in permanent visual disturbance or even blindness. Any effort to restore vision in such condition would require replacement of the highly specialized retinal cells. Stem/progenitor cells have been proposed as a potential source of new retina-specific cells to replace those lost due to retina injury. Evidence to date suggests that continued development of stem cell therapies may ultimately lead to viable treatment options for retina injury. A wide range of stem/progenitor cells from various sources is currently being investigated for the treatment of retinal injury. This article reviews the recent achievements about stem/progenitor cell source for retinal repair.
Bi
Yong-Yan
YY
Department of Neurosurgery, No. 3 People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feng
Dong-Fu
DF
Pan
Dong-Chao
DC
D000818:Animals; D016026:Bone Marrow Transplantation / Q000379:methods; D016380:Brain Tissue Transplantation / Q000379:methods; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology; D004847:Epithelial Cells / Q000166:cytology / Q000637:transplantation*; D006801:Humans; D012160:Retina / Q000166:cytology / Q000637:transplantation*; D012164:Retinal Diseases / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*