title: Discontinued drugs in 2008: oncology drugs.
abstract: The failure of drug candidates in clinical development remains a critical issue for the pharmaceutical and biotechnology industries. This article documents those oncology drugs discontinued in 2008 and briefly reviews reasons for termination of development. Source information was derived from a search of the Pharmaprojects database for drugs reaching phase I-III clinical trials.
authors: Cancer Research UK, Drug Development Office, 61 Lincoln's Inn Fields, London WC2A 3PX, UK. Robert.williams@cancer.org.uk
authors: Robert
authors: R
authors: Williams
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D016208:Databases, Factual; D015195:Drug Design; D004345:Drug Industry / Q000639:trends; D015507:Drugs, Investigational / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents; D015507:Drugs, Investigational