Comparative embryology without a microscope: using genomic approaches to understand the evolution of development.
Until recently, understanding developmental conservation and change has relied on embryological comparisons and analyses of single genes. Several studies, including one recently published in BMC Biology, have now taken a genomic approach to this classical problem, providing insights into how selection operates differentially across the life cycle.
Garfield
David A
DA
Biology Department and Institute for Genome Science & Policy, Duke University, Durham, NC 27708, USA. dag23@duke.edu
Wray
Gregory A
GA
D000818:Animals; D005075:Biological Evolution; D047108:Embryonic Development / Q000235:genetics*; D020869:Gene Expression Profiling; D018507:Gene Expression Regulation, Developmental; D016678:Genome; D006801:Humans; D013045:Species Specificity