title: Optimization techniques in cardiac resynchronization therapy.
abstract: Cardiac resynchronization therapy improves symptoms and cardiac function, as well as reduces mortality in patients with progressive congestive heart failure, reduced left ventricular ejection fraction and a left bundle branch block on the surface electrocardiogram. As many as 30% of patients fail to have an adequate response. The interplay between the atrioventricular delay and the contribution of a properly timed atrial contraction to ventricular filling along with a properly timed sequence of activation of the right and left ventricular is crucial to maximizing the benefits of cardiac resynchronization therapy devices.
authors: Zena & Michael A Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY 10029, USA. avi.fischer@mssm.edu
authors: Avi
authors: A
authors: Fischer
mesh_terms: D001283:Atrioventricular Node / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002037:Bundle-Branch Block / Q000628:therapy; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004452:Echocardiography; D004562:Electrocardiography; D006329:Heart Conduction System / Q000502:physiology; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000628:therapy