title: Prognosis of idiopathic downbeat nystagmus.
abstract: Downbeat nystagmus (DBN) is a common form of acquired involuntary ocular oscillation overriding fixation. Little is known about the natural evolution of DBN in idiopathic cases. Therefore, eye movements were recorded in seven patients with idiopathic DBN by search-coil technique over a course of up to six years. Neither the slow-phase velocity (SPV) nor the dependency of the SPV on gaze position as an indicator of dysfunction of the oculomotor velocity-to-position integrator changed significantly over the time course investigated in this study.
authors: Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany. judith.wagner@med.uni-muenchen.de
authors: Judith
authors: J
authors: Wagner
authors: Nadine
authors: N
authors: Lehnen
authors: Stefan
authors: S
authors: Glasauer
authors: Michael
authors: M
authors: Strupp
authors: Thomas
authors: T
authors: Brandt
mesh_terms: D000368:Aged; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000503:physiopathology*; D011379:Prognosis