title: Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system.
abstract: Poly(epsilon-caprolactone)-poly(ethylene glycol) (PCL-PEG) copolymers are important synthetic biomedical materials with amphiphilicity, controlled biodegradability, and great biocompatibility. They have great potential application in the fields of nanotechnology, tissue engineering, pharmaceutics, and medicinal chemistry. This review introduced several aspects of PCL-PEG copolymers, including synthetic chemistry, PCL-PEG micro/nanoparticles, PCL-PEG hydrogels, and physicochemical and toxicological properties.
authors: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
authors: XiaWei
authors: X
authors: Wei
authors: ChangYang
authors: C
authors: Gong
authors: MaLing
authors: M
authors: Gou
authors: ShaoZhi
authors: S
authors: Fu
authors: QingFa
authors: Q
authors: Guo
authors: Shuai
authors: S
authors: Shi
authors: Feng
authors: F
authors: Luo
authors: Gang
authors: G
authors: Guo
authors: LiYan
authors: L
authors: Qiu
authors: ZhiYong
authors: Z
authors: Qian
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D001673:Biodegradation, Environmental; D004337:Drug Carriers; D005026:Ethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D020100:Hydrogels / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D011091:Polyesters / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D004337:Drug Carriers; D005026:Ethylene Glycols; D020100:Hydrogels; D011091:Polyesters; C476300:poly(epsilon-caprolactone)-b-poly(ethylene glycol)