title: [The use of melaxen in combined therapy of arterial hypertension in subjects occupied in assembly line production].
abstract: The work was designed to study effect of melaxen on circadian chronostructure of arterial pressure and pulse rate in subjects with arterial hypertension occupied in assembly line production. A total of 57 patients were examined of whom 23 received teveten together with melaxen and 34 were treated with teveten alone for 3 weeks. Inclusion of melaxen in combined therapy of hypertension reduced arterial pressure and normalized disturbed circadian hemodynamics. It is concluded that combined therapy effectively eliminates sleep disorders frequent in this group of patients.
authors: Iu N
authors: IuN
authors: Zamotaev
authors: A Kh
authors: AKh
authors: Enikeev
authors: N M
authors: NM
authors: Kolomoets
mesh_terms: D000179:Acrylates / Q000008:administration & dosage / Q000627:therapeutic use*; D000284:Administration, Oral; D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D002492:Central Nervous System Depressants / Q000008:administration & dosage / Q000627:therapeutic use; D002940:Circadian Rhythm / Q000502:physiology; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007221:Industry; D008550:Melatonin / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009784:Occupational Diseases / Q000188:drug therapy* / Q000503:physiopathology; D016273:Occupational Exposure / Q000009:adverse effects*; D013876:Thiophenes / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000179:Acrylates; D000959:Antihypertensive Agents; D002492:Central Nervous System Depressants; D007093:Imidazoles; D013876:Thiophenes; C068373:eprosartan; D008550:Melatonin