title: [Kidney sicknesses associated with gene of the drepanocytose in the Department of Nephrology and Haemodialysis of the CHU of Point G].
abstract: OBJECTIVE
  To assess renal features joint to gene of the drepanocytose.
  
  
  METHODS
  It concerned a descriptive transversal study from June 1995 to January 2004. Were included drepanocytose patients admitted hospital or seeing for consulting having one of the features: haematuria, proteinuria, leucocyturia, positive aeroculture, urea increasing and/ or of blood creatinine. The analysis and data capture were conducted on SPSS 11.0. The statistic text was the Khi square with a threshold of signification p<0.05.
  
  
  RESULTS
  The folders of 30 patients (18 m and 12 w) were collected. The average age was of 3104 years (5 and 64 years). The most hospitalization reasons encountered were the oedema syndrome (26.7%) and the overall haematuria (20%). The majority of the patients were heterozygote 93.33%. The kidney sicknesses encountered were: acute renal deficiency 40%, the macroscopic haematuria 20%, the nephritic syndrome 20%, chronic renal deficiency 13.4%, urinary infection 3.3% and microscopic haematuria 33%.
  
  
  CONCLUSIONS
  The sicklaneny's gene in Mali is associated to a renal morbidity. The increased frequency of drepanocytaria feature bearers must be confirmed by other studies in order to establish a strategic of treatment of this pathology.
authors: Service de Néphrologie et d'Hémodialyse, CHU du Point G.
authors: S
authors: S
authors: Fongoro
authors: D
authors: D
authors: Diallo
authors: D A
authors: DA
authors: Diallo
authors: K A
authors: KA
authors: Tchiango
authors: M K
authors: MK
authors: Maiga
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009398:Nephrology; D006435:Renal Dialysis; D014573:Urology Department, Hospital; D055815:Young Adult
chemical_list: D006451:Hemoglobin, Sickle