title: The relationship between severe mental illness and diabetes.
abstract: This article reviews what is known about the incidence of diabetes in patients with severe mental illness. Studies performed before antipsychotic medications and atypical antipsychotics were introduced are discussed. Most but not all of these studies found elevated rates of diabetes in patients with schizophrenia and bipolar disorder compared with the general population, although many of these studies had a number of methodological limitations. Possible mechanisms that may account for an increased risk of diabetes in patients with psychotic and bipolar disorders are then considered, including biological, demographic, socioeconomic, and behavioral hypotheses.
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000523:psychology*; D006801:Humans; D001523:Mental Disorders / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D012307:Risk Factors; D012959:Socioeconomic Factors
chemical_list: D014150:Antipsychotic Agents