title: Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease.
abstract: The physiopathology of Chagas' disease has been largely defined in murine infections with virulent strains which partially represent parasite diversity. This report reviews our studies with Sylvio X10/4 parasites, a Trypanosoma cruzi clone that induces no acute phase but in C3H/He mice leads to chronic myocarditis resembling the human disease.
authors: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, Av. Professor Lineu Prestes, 1730, São Paulo, SP, CEP-05508-000, Brazil.
authors: Cláudio R F
authors: CR
authors: Marinho
authors: Luis N
authors: LN
authors: Nuñez-Apaza
authors: Karina R
authors: KR
authors: Bortoluci
authors: André L
authors: AL
authors: Bombeiro
authors: Daniella Z
authors: DZ
authors: Bucci
authors: Marcos G
authors: MG
authors: Grisotto
authors: Luiz R
authors: LR
authors: Sardinha
authors: Christian E
authors: CE
authors: Jorquera
authors: Sergio
authors: S
authors: Lira
authors: Maria Regina D'Império
authors: MR
authors: Lima
authors: José M
authors: JM
authors: Alvarez
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000276:immunology / Q000469:parasitology*; D002908:Chronic Disease; D004195:Disease Models, Animal; D006790:Host-Parasite Interactions; D051379:Mice; D018512:Parasitemia / Q000276:immunology / Q000469:parasitology; D014349:Trypanosoma cruzi / Q000472:pathogenicity / Q000502:physiology*