title: Evaluation of endocrine disruptor levels in Kafue Lechwe (Kobus leche kafuensis) samples from the Blue Lagoon National Park of Zambia.
abstract: The concentrations of endocrine disruptors were determined in 36 liver tissue, serum and whole blood sample extracts drawn from 15 Blue Lagoon National Park Kafue lechwe. Out of 10 analytes evaluated, 89% of the sample extracts showed very high dieldrin concentrations of between 0.08–100 μg/mL in serum, 0.08–24.8 μg/mL in whole blood and 0.08–4.6 μg/g wet weight in liver tissue extracts. pp-DDE was detected in 83% of the sample extracts at 0.006–5.1 μg/mL in serum, 0.006–8.5 μg/mL in whole blood and 0.006–0.12 μg/g wet weight in liver tissue extracts. There was strong correlation between pp-DDE and dieldrin in all the three matrices. Deltamethrin and endosulfan detected at 50% frequency each. Percent recoveries in spiked laboratory blanks ranged between 60–100% while calculated detection limits ranged from 0.004 to 0.21 μg/mL for all the endocrine disruptors evaluated.
authors: Department of Chemistry, Faculty of Science, University of Botswana, P/B 00704, Gaborone, Botswana kwenga.sichilongo@mopipi.ub.bw
authors: Kwenga
authors: K
authors: Sichilongo
authors: Nelson
authors: N
authors: Torto
mesh_terms: D000818:Animals; D000866:Antelopes / Q000097:blood / Q000378:metabolism*; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood / Q000378:metabolism; D004026:Dieldrin / Q000097:blood / Q000378:metabolism; D052244:Endocrine Disruptors / Q000032:analysis*; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000378:metabolism; D008297:Male; D015024:Zambia
chemical_list: D052244:Endocrine Disruptors; D004785:Environmental Pollutants; D003633:Dichlorodiphenyl Dichloroethylene; D004026:Dieldrin