Chemical shift anisotropy selective inversion.
Magic angle spinning (MAS) is used in solid-state NMR to remove the broadening effects of the chemical shift anisotropy (CSA). In this work we investigate a technique that can reintroduce the CSA in order to selectively invert transverse magnetization. The technique involves an amplitude sweep of the radio frequency field through a multiple of the spinning frequency. The selectivity of this inversion mechanism is determined by the size of the CSA. We develop a theoretical framework to describe this process and demonstrate the CSA selective inversion with numerical simulations and experimental data. We combine this approach with cross-polarization (CP) for potential applications in multi-dimensional MAS NMR.
Caporini
Marc A
MA
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Turner
Christopher J
CJ
Bielecki
Anthony
A
Griffin
Robert G
RG
D000465:Algorithms; D016880:Anisotropy; D003198:Computer Simulation; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008956:Models, Chemical; D012680:Sensitivity and Specificity; D013113:Spin Labels
D013113:Spin Labels