title: Prevalence of Salmonella associated with chick mortality at hatching and their susceptibility to antimicrobial agents.
abstract: The prevalence of Salmonella associated mortality at hatching was investigated in three hatcheries in Jos, central Nigeria. Their susceptibility to antimicrobial agents was also evaluated. S. Kentucky and S. Hadar were isolated. While half of the isolates were from internal organs, 26.7% came from meconial swabs of dead-in-shell embryos, 17.8% from intestinal samples and 4.4% from egg shells. S. Hadar is known to colonise only the gut and is classified as non-invasive, but in this study 82% were obtained from internal organs which suggests that infections with this serotype may also cause invasive disease. Antimicrobial susceptibility tests showed a high prevalence of antimicrobial resistance in the study area with complete resistance to gentamycin, enrofloxacin, nalidixic acid, tetracycline and streptomycin and substantial resistance to triple sulphur and ciprofloxacin. Six multiple resistance profiles were recorded with a high level of multiple resistance to quinolones. Quinolone resistance has implications for veterinary and human therapy as their misuse in poultry could lead to the emergence of resistant animal and zoonotic pathogens.
authors: Bacterial Research Department, National Veterinary Research Institute, PMB 01, Vom, Plateau, Nigeria. lawal54@yahoo.com
authors: Maryam
authors: M
authors: Muhammad
authors: Lawal U
authors: LU
authors: Muhammad
authors: Abdul-Ganiyu
authors: AG
authors: Ambali
authors: Aliyu U
authors: AU
authors: Mani
authors: Samuel
authors: S
authors: Azard
authors: Lisa
authors: L
authors: Barco
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002645:Chickens; D015169:Colony Count, Microbial; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D009549:Nigeria / Q000453:epidemiology; D011201:Poultry Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D015995:Prevalence; D012475:Salmonella / Q000187:drug effects* / Q000302:isolation & purification / Q000502:physiology*; D012481:Salmonella Infections, Animal / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D012703:Serotyping
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents