Two cases of hematuria with hemoglobin C trait.
Patients with sickle cell disease commonly experience painless hematuria. Hematuria may be found in patients with sickle cell trait, sickle cell anemia, and sickle cell hemoglobin C disease, but it is believed to be uncommon in patients with other hemoglobinopathies, such as hemoglobin C disease and hemoglobin C trait. We report two cases of children with hemoglobin C trait who presented with persistent painless hematuria. Because it is possible that hematuria in a patient with hemoglobin C trait is purely coincidental, all patients with a hemoglobinopathy and hematuria should undergo a complete evaluation so as not to overlook other causes of hematuria.
Spencer
John David
JD
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Sanders
John T
JT
Ault
Bettina H
BH
D000293:Adolescent; D001741:Black or African American / Q000235:genetics; D002648:Child; D006417:Hematuria / Q000209:etiology*; D006450:Hemoglobin SC Disease / Q000150:complications*; D006453:Hemoglobinopathies / Q000150:complications*; D006801:Humans; D008297:Male; D014481:United States