title: HorC, a hop-resistance related protein, presumably functions in homodimer form.
abstract: To determine whether two HorC molecules coordinately form a single unit, the functional properties of covalently linked dimers of HorC encoded by tandemly fused horC genes were studied. Lactobacillus brevis introduced with the fused horC genes and a single horC gene exhibited same degree of resistance to hop compounds and cetyltrimethylammonium bromide. This suggests that HorC functions as a homodimer.
authors: Research Laboratories of Brewing Technology, Asahi Breweries, Ltd., Moriya, Ibaraki, Japan.
authors: Kazumaru
authors: K
authors: Iijima
authors: Koji
authors: K
authors: Suzuki
authors: Shizuka
authors: S
authors: Asano
authors: Tomoo
authors: T
authors: Ogata
authors: Yasushi
authors: Y
authors: Kitagawa
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D001515:Beer / Q000382:microbiology*; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D055503:Protein Multimerization; D020836:Protein Structure, Quaternary
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002593:Cetrimonium Compounds; D000077286:Cetrimonium