title: Primary myelodysplastic syndrome in Jordan: a single-centre experience.
abstract: OBJECTIVE
  Study of the disease patterns and clinical evaluation of myelodysplastic syndrome (MDS).
  
  
  METHODS
  A retrospective analysis was carried out on 85 patients, with MDS who were followed up over a period of 23 years at Jordan University Hospital, Amman, Jordan. Cases were analyzed according to the French, American and British Classification.
  
  
  RESULTS
  Of the 85 patients, 42 (49.4%) were females and 43 (50%) males; mean age was 59 +/- 19 years (range 18-88). Most subtypes found in patients were refractory anemia (RA) in 27 (31.8%) and RA with excess blasts (RAEB) in 28 (32.9%). Adverse prognostic indicators were RAEB subtype and requirement for blood transfusion.
  
  
  CONCLUSIONS
  Our findings showed that MDSs appeared at a younger age and tended to be of the aggressive subtype. Chronic myelomonocytic leukemia subtype seemed to appear dominantly in men.
authors: Department of Hematology and Oncology, Jordan University Hospital, Amman, Jordan. aawidi@yahoo.com
authors: Abdalla
authors: A
authors: Awidi
authors: Ahmad
authors: A
authors: Magableh
authors: Ziad
authors: Z
authors: Taimeh
authors: Hashim
authors: H
authors: Ayyad
authors: Nazzal
authors: N
authors: Bsoul
authors: Musleh
authors: M
authors: Tarawneh
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000754:Anemia, Refractory, with Excess of Blasts / Q000453:epidemiology / Q000503:physiopathology*; D000756:Anemia, Sideroblastic / Q000453:epidemiology / Q000503:physiopathology*; D003906:Developing Countries; D018450:Disease Progression; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007597:Jordan / Q000453:epidemiology; D053208:Kaplan-Meier Estimate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult