Papillary carcinoma of the thyroid developed in congenital dyshormonogenetic hypothyroidism without goiter: Diagnosis by FNAB.
A 5-year-old girl known to have congenital dyshormonogenetic hypothyroidism since birth and under appropriate treatment (without goiter) developed a thyroid nodule which was found in the clinical follow-up. Fine-needle aspiration biopsy of the nodule allowed to diagnose a papillary thyroid carcinoma, a diagnosis which was certified by the surgical specimen exam. Dyshormonogenetic goiter may rarely associate with thyroid carcinoma. The present case appears unique since goiter was not present.
Drut
Ricardo
R
Department of Pathology, Superiora Sor María Ludovica Children's Hospital, 1900 La Plata, Argentina. patologi@netverk.com.ar
Moreno
Adrian
A
D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D002675:Child, Preschool; D003409:Congenital Hypothyroidism / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005260:Female; D006042:Goiter / Q000473:pathology; D006801:Humans; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery