title: Four new fatty acid esters from the Feces of Trogopterus xanthipes.
abstract: Four new fatty acid esters have been isolated from Feces Trogopterus. Their structures were determined by spectroscopic and chemical methods to be bis(7-hydroxyheptyl) icosanedioate (1), bis(7-hydroxyheptyl) heptadecanedioate (2), bis(7-hydroxyheptyl) decanedioate (3), and bis(7-hydroxyheptyl) octanedioate (4). In the anticoagulative assay, compounds 3 and 4 had significant antithrombin activity.
authors: Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Traditional Chinese Medicine, Nanjing, 210046, People's Republic of China.
authors: Nian-Yun
authors: NY
authors: Yang
authors: Wei-Wei
authors: WW
authors: Tao
authors: Jin-Ao
authors: JA
authors: Duan
authors: Jian-Ming
authors: JM
authors: Guo
authors: Ling-Ling
authors: LL
authors: Cao
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D005227:Fatty Acids / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D005243:Feces / Q000737:chemistry*; D015394:Molecular Structure; D011817:Rabbits; D012589:Sciuridae / Q000378:metabolism*; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D000925:Anticoagulants; D004365:Drugs, Chinese Herbal; D005227:Fatty Acids; D013917:Thrombin