Kaposiform hemangioendothelioma (with Kasabach Merritt syndrome) of the head and neck: case report and review of the literature.
An infant initially diagnosed with a parotid hemangioma presented with stridor and thrombocytopenia. Diagnosis of Kaposiform hemangioendothelioma was confirmed with biopsy. The child succumbed to multi-system organ failure related to consumptive coagulopathy despite aggressive medical management. Kaposiform hemangioendothelioma is a rare head and neck tumor that may be mistaken for a hemangioma on preliminary diagnosis, which may lead to increased morbidity and mortality especially in the setting of Kasabach-Merritt phenomenon. A platelet count may provide an early and important clue to the possibility of coagulopathy; prompting physicians to look for a diagnosis other than a simple hemangioma.
Mukerji
Shraddha S
SS
Department of Pediatric Otolaryngology, University of Texas Medical Branch, Galveston, TX, USA.
Osborn
Alex J
AJ
Roberts
Jess
J
Valdez
Tulio A
TA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018450:Disease Progression; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006390:Hemangioendothelioma / Q000175:diagnosis / Q000628:therapy; D018324:Hemangioma, Capillary / Q000175:diagnosis / Q000628:therapy; D006392:Hemangioma, Cavernous / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D059885:Kasabach-Merritt Syndrome; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D007828:Laryngoscopy / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D009102:Multiple Organ Failure / Q000175:diagnosis* / Q000209:etiology; D018570:Risk Assessment; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000628:therapy; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis / Q000628:therapy; D013921:Thrombocytopenia / Q000175:diagnosis / Q000628:therapy; D014139:Tracheostomy / Q000379:methods; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000628:therapy