Genetic and environmental influences on restrained eating behavior.
OBJECTIVE
We examined the relative contributions of genetic and environmental influences to restrained eating.


METHODS
Restrained eating was assessed by the Restraint Scale in a survey mailed to all twins enrolled in the University of Washington Twin Registry. We used structural equation modeling to estimate genetic and nongenetic contributions to restrained eating.


RESULTS
1,196 monozygotic (MZ), 456 same-sex dizygotic (DZ) twins, and 447 opposite-sex twins were included in analyses. Restraint Scale scores were more closely correlated in MZ twins (r(male) = .55, r(female) = .55) than in same-sex DZ twins (r(male) = .31, r(female) = .19). Based on structural equation modeling, the estimated heritability for restrained eating, adjusted for body mass index (BMI) and sex, was 43% (95% confidence interval 35-50%). There was little evidence for common environmental effects.


CONCLUSIONS
These results indicate an inherited component to restrained eating. Genes could influence restrained eating directly or through inherited mediators such as personality factors or tendencies to gain weight.
Schur
Ellen
E
Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA. ellschur@u.washington.edu
Noonan
Carolyn
C
Polivy
Janet
J
Goldberg
Jack
J
Buchwald
Dedra
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016009:Chi-Square Distribution; D004435:Eating / Q000235:genetics*; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D018579:Patient Selection; D012931:Social Environment; D011795:Surveys and Questionnaires; D014429:Twins, Dizygotic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*