title: Synthetic approach to telomerase inhibitor dictyodendrin B: synthesis of the pyrrolo[2,3-c]carbazole core.
abstract: The core structure of the telomerase inhibitor, dictyodendrin B, was synthesized by using the palladium-catalyzed cross-coupling reaction of 3-aryl-1-(2-arylethyl)-4-hydroxy-2,5-bismethoxycarbonylpyrrole triflate with 7-alkoxyindole-3-boronate as the key step.
authors: Graduate School of Science and Technology, Nagasaki University, Japan.
authors: Shotaro
authors: S
authors: Hirao
authors: Yumiko
authors: Y
authors: Sugiyama
authors: Masatomo
authors: M
authors: Iwao
authors: Fumito
authors: F
authors: Ishibashi
mesh_terms: D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D002384:Catalysis; D010165:Palladium / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D019098:Telomerase / Q000037:antagonists & inhibitors*
chemical_list: D002227:Carbazoles; D011758:Pyrroles; D018894:Reverse Transcriptase Inhibitors; C505029:dictyodendrin B; C041514:carbazole; D010165:Palladium; D019098:Telomerase