[Vitamin D deficiency].
The importance of vitamin D for osteoporosis and fractures has been known for more than 40 years. Vitamin D deficiency is diagnosed by measuring 25-hydroxyvitamin D (25-OHD), which should be > 50 nmol/l year round. Recent research suggests that a number of severe diseases could be prevented by increasing 25-OHD to 80 nmol/l. Despite a strong focus on such increase, recommendations for intake of Vitamin D have not been changed and the present recommendations are too low even to ensure > 50 nmol/l. To achieve optimal concentrations > 80 nmol/l, we estimate that 50-70 microgram of vitamin D per day for everyone from the age of 10 years is necessary. Until the safety of this dose has been further documented, we recommend 35-38 micrograms/day.
Hey
Henrik
H
Medicinsk Afdeling, Sygehus Lillebaelt, Vejle, DK-7100 Vejle. Henrik.Hey@slb.regionsyddanmark.dk
Schmedes
Anne
A
Horn
Peer
P
Brandslund
Ivan
I
D000328:Adult; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D009751:Nutritional Requirements; D010024:Osteoporosis / Q000517:prevention & control; D012016:Reference Values; D014466:Ultraviolet Rays; D014807:Vitamin D / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control
D014807:Vitamin D; C104450:25-hydroxyvitamin D