title: Nephrotic-range proteinuria with small glomerular fibrillary deposits in a patient on diphenylhydantoin treatment.
abstract: BACKGROUND
  Although the exact role of the diphenylhydantoin treatment on the immune system is still unclear, prolonged administration of diphenylhydantoin has been suggested to be associated with immune-based disorders and syndromes.
  
  
  METHODS
  A case of fibrillary glomerulonephritis associated with DPH treatment is reported. This is the first reported case of fibrillary glomerulonephritis associated with this commonly used common anticonvulsive drug.
  
  
  CONCLUSIONS
  A more routine surveillance for proteinuria in patients receiving DPH is recommended.
authors: Department of Internal Medicine, Division of Nephrology, Faculty of Medicine, University of Mersin, Mersin, Turkey.
authors: Ahmet Alper
authors: AA
authors: Kiykim
authors: Gultekin
authors: G
authors: Genctoy
authors: Mehmet
authors: M
authors: Horoz
authors: Sibel
authors: S
authors: Sari
authors: Ebru
authors: E
authors: Gok
authors: Banu
authors: B
authors: Coskun
authors: Nejat
authors: N
authors: Yilmaz
authors: Iclal
authors: I
authors: Gurses
mesh_terms: D005921:Glomerulonephritis / Q000139:chemically induced* / Q000150:complications* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D010503:Periodic Acid-Schiff Reaction; D010672:Phenytoin / Q000009:adverse effects*; D011507:Proteinuria / Q000139:chemically induced* / Q000150:complications* / Q000473:pathology
chemical_list: D010672:Phenytoin