Articular aspergillosis: case report and review of the literature.
The incidence of invasive aspergillosis is increasing due to more frequent use of immunosuppressant agents in patients with autoimmune diseases, hematological malignancies, and solid organ and hematopoietic stem cell transplants. Invasive aspergillosis most commonly affects the lungs, sinuses, and brain. Aspergillosis affecting the musculoskeletal system is rare. We describe here a case of articular aspergillosis in a febrile neutropenic patient successfully treated with voriconazole and caspofungin, and briefly review the 10 cases of articular aspergillosis that have previously been described in the literature.
Yu
Oriana Hoi Yun
OH
Department of Internal Medicine, Jewish General Hospital, McGill University, 3755 Cote St. Catherine Road, Montreal, Quebec, Canada H3T 1E2. oriana.huiyu@yahoo.ca
Keet
Annick Wong Wong
AW
Sheppard
Donald C
DC
Brewer
Timothy
T
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000382:microbiology*; D001231:Aspergillus flavus / Q000254:growth & development*; D002358:Cartilage, Articular / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009140:Musculoskeletal Diseases / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents