Cutaneous Rosai-Dorfman disease.
Rosai-Dorfman disease is a self-limited benign disease. Rosai and Dorfman first described it in 1969, and the etiology of the disease remains unknown. Main manifestations are cervical adenopathy associated with fever, leukocytosis with neutrophilia and polyclonal gamaglobulinemia. Although the skin is the most common site of extra nodal disease, Rosai-Dorfman disease restricted to the skin is very rare with only a few cases described in the literature. This paper reports a rare case of cutaneous Rosai-Dorfman with skin as the sole site, and reviews the controversies of diagnosis and treatment.
Landim
Fábio Machado
FM
Serviço Tumores Cutâneos, Instituto do Câncer do Ceará, Fortaleza (CE), Brazil.
Rios
Helena de Oliveira
Hde O
Costa
Carolina Oliveira
CO
Feitosa
Roney Gonçalves Fechine
RG
Rocha Filho
Francisco Dário
FD
Costa
Adriana Alencar Araújo
AA
D000328:Adult; D015618:Histiocytosis, Sinus / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D012871:Skin Diseases / Q000473:pathology / Q000601:surgery