A novel near-infrared protein assay based on the dissolution and aggregation of aptamer-wrapped single-walled carbon nanotubes.
We describe herein a novel, selective and sensitive biosensing system based on the dissolution and aggregation of single-walled carbon nanotubes directed by the aptamer-protein interaction for the clinical assays of proteins.
Chen
Hui
H
Department of Chemistry, CAM & IBS, Fudan University, Shanghai, PR China.
Yu
Cheng
C
Jiang
Chunming
C
Zhang
Song
S
Liu
Baohong
B
Kong
Jilie
J
D000595:Amino Acid Sequence; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D008969:Molecular Sequence Data; D037742:Nanotubes, Carbon / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared; D013917:Thrombin / Q000032:analysis*
D052157:Aptamers, Nucleotide; D037742:Nanotubes, Carbon; D013917:Thrombin