title: Constituents of the leaves of Magnolia ovata.
abstract: Two new lignans, magnovatins A (1) and B (2), along with nine known compounds, were isolated from the leaves of Magnolia ovata. The known compounds were identified as acuminatin (3), licarin A (4), kadsurenin M, 4-O-demethylkadsurenin M, oleiferin A, oleiferin C, spathulenol, parthenolide, and 11,13-dehydrocompressanolide. In addition, compounds 1 and 2 yielded four new derivatives (1a, 1b, 2a, and 2b). The structures of the new compounds were established on the basis of spectrometric data evaluation. Free-radical scavenging and antimicrobial activities of the major compunds 1, 3, and 4 were investigated.
authors: Departamento de Quimica, Universidade Federal do Parana, CP 19081, 81530-900 Curitiba, PR, Brazil.
authors: Letícia Ferrari L
authors: LF
authors: Barros
authors: Andersson
authors: A
authors: Barison
authors: Marcos José
authors: MJ
authors: Salvador
authors: Renato
authors: R
authors: de Mello-Silva
authors: Elaine C
authors: EC
authors: Cabral
authors: Marcos N
authors: MN
authors: Eberlin
authors: Maria Elida A
authors: ME
authors: Stefanello
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001938:Brazil; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D017705:Lignans / Q000302:isolation & purification / Q000494:pharmacology; D031566:Magnolia / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects; D015003:Yeasts / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D005419:Flavonoids; D016166:Free Radical Scavengers; D006027:Glycosides; D017705:Lignans; C432503:licarin A; C077860:acuminatin