title: Implication of normal liver enzymes in liver disease.
abstract: Chronic liver disease is usually asymptomatic until its late stages and also significant hepatic necroinflammation and fibrosis may be present in persistently normal ALT levels HBV, HCV carriers or similarly, in patients with nonalcoholic fatty liver disease. Given the large number of persons in the general population which may harbor a clinically significant liver disease behind the screen of normal alanine aminotransferase, more attention should be devoted to future research for alternative noninvasive markers of liver damage.
authors: Gastroenterologia & Epatologia, DIBIMIS, Università di Palermo, 90127 Palermo, Italy. vcalvaruso@libero.it
authors: Vincenza
authors: V
authors: Calvaruso
authors: Antonio
authors: A
authors: Craxì
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D006801:Humans; D008099:Liver / Q000201:enzymology* / Q000473:pathology*; D008107:Liver Diseases / Q000175:diagnosis*; D012680:Sensitivity and Specificity
chemical_list: D000410:Alanine Transaminase