Identification of Chlamydia trachomatis in a patient with ocular lymphoma.
Accumulating evidence suggests that infectious agents may play a role in ocular adnexa lymphomas (OALs) of MALT-type [1-4]. In particular, Chlamydia psittaci, the causative agent of psittacosis, has been detected by PCR in most patients from Italy or isolated eastern Asiatic countries with OALs in absence of other Chlamydia species [4-8]. These patients have also been shown to have a complete or partial response to doxycycline, recognized to be a cheap and safe treatment in these patients [5,6]. In contrast, OAL patients from other geographic areas and with different genetic background were found to be negative for C. psittaci DNA or had a quite variable response to antibiotic treatment, assuming that this pathogen might not play a ubiquitous role in OALs and that bacterial infection is not associated with OAL [8-12].
Contini
Carlo
C
Seraceni
Silva
S
Carradori
Silvia
S
Cultrera
Rosario
R
Perri
Paolo
P
Lanza
Francesco
F
D002690:Chlamydia Infections / Q000188:drug therapy; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D004318:Doxycycline / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000382:microbiology*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000382:microbiology*; D008875:Middle Aged; D012329:RNA, Bacterial / Q000032:analysis
D012329:RNA, Bacterial; D004318:Doxycycline