title: [Current options of prenatal diagnosis in congential diaphragmatic hernia].
abstract: OBJECTIVE
  The aim of this article is to review the current options of prenatal diagnosis in congential diaphragmatic hernia (CDH).
  
  
  METHODS
  Systematic review.
  
  
  METHODS
  Institute for the Care of Mother and Child, 3rd Medical Faculty, Prague.
  
  
  METHODS
  Review of recent published data.
  
  
  CONCLUSIONS
  The basic method for prenatal diagnosis of congenital diaphragmatic hernia is 2D ultrasonography: measurement of lung-to-head ratio (LHR), observed to expected lung to head ratio (observed to expected LHR - O/E LHR), localization of diaphragmatic defect, assessment of liver position and presence of associated anomalies (negative prognostic factors). Prenatal diagnosis can be supplied with 3D ultrasonography and magnetic resonace (imaging methods for valid measurement of fetal lung volume and/or presence of associated congenital defects confirmation). The reactivity of intrapulmonary arteries are evaluated by hyperoxygenation test and measurement of arterial Doppler parameters. Isolated diaphragmatic hernia is not an indication for invasive prenatal diagnostic methods. Important part of succesful prenatal diagnosis and therapy of CDH is concentration of cases in specialized centre.
authors: Ustav patologie VFN a 1. LF UK. z.stranak@seznam.cz
authors: Z
authors: Z
authors: Stranák
authors: I
authors: I
authors: Kucerová
authors: I
authors: I
authors: Urbánková
authors: B
authors: B
authors: Goldová
authors: I
authors: I
authors: Vítková
authors: M
authors: M
authors: Rygl
authors: K
authors: K
authors: Pýcha
authors: L
authors: L
authors: Krofta
mesh_terms: D005260:Female; D006548:Hernia, Diaphragmatic / Q000175:diagnosis / Q000000981:diagnostic imaging*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D018810:Magnetic Resonance Angiography; D011247:Pregnancy; D016216:Ultrasonography, Prenatal