title: Cultivation and bioactivity assessment of Grifola frondosa fruiting bodies on olive oil press cakes substrates.
abstract: Grifola frondosa, a medicinal and edible mushroom, was cultivated on substrates composed of olive oil press cakes with different supplements. Crude extracts were prepared from mature fruiting bodies and tested for their capacity to stimulate splenocyte proliferation. Two wild-growing fruiting bodies were extracted for comparison. Olive oil press cakes reduced the mushroom yield, and the best biological efficiency was obtained on substrates supplemented with wheat bran and without olive oil press cakes. All extracts were capable of inducing splenocyte proliferation and were half as effective as the positive control (6.0 microg/mL phytohaemagglutinin). No correlation between substrate composition and bioactivity could be established. Extracts from wild-growing G. frondosa were superior to cultivated ones in respect to biological activity.
authors: Scientific Research Centre Bistra Ptuj, 2250 Ptuj, Slovenia. andrej.gregori@gmail.com
authors: Andrej
authors: A
authors: Gregori
authors: Mirjan
authors: M
authors: Svagelj
authors: Marin
authors: M
authors: Berovic
authors: Yanfang
authors: Y
authors: Liu
authors: Jingsong
authors: J
authors: Zhang
authors: Franc
authors: F
authors: Pohleven
authors: Dusan
authors: D
authors: Klinar
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D048690:Fruiting Bodies, Fungal / Q000254:growth & development*; D048691:Grifola / Q000254:growth & development*; D051379:Mice; D008807:Mice, Inbred BALB C; D000069463:Olive Oil; D010938:Plant Oils / Q000737:chemistry*; D013154:Spleen / Q000166:cytology; D014866:Waste Products
chemical_list: D000069463:Olive Oil; D010938:Plant Oils; D014866:Waste Products