Photoinduced Intramolecular addition of 3-acyl-2-haloindoles to alkenes.
1,2-Fused indoles and pyrroles were prepared via an efficient intramolecular photoaddition reaction of 1-(omega-alkenyl)-2-haloindole-3-carbaldehydes and 1-(omega-alkenyl)-2-chloropyrrole-3-carbaldehydes. The presence of an acyl group was necessary for the photocyclization reactions. The halogen-atom-retained exo- and endo-cyclization products were generally produced with results similar to those of an atom-transfer cyclization reaction. In contrast, unsaturated cyclization products were obtained in the photoreaction of substrates having methyl groups on the vinyl group.
Lu
Shen-Ci
SC
State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, PR China.
Duan
Xiao-Yong
XY
Shi
Zong-Jun
ZJ
Li
Bing
B
Ren
Yu-Wei
YW
Zhang
Wei
W
Zhang
Yong-Hui
YH
Tu
Zhi-Feng
ZF