Synthesis of PNU-95666E.
PNU-95666E is being developed for the treatment of Parkinson's disease. This review will describe the syntheses of this D2 agonist proceeding from the very early routes to a usable production route.
Wuts
P G
PG
1500-91-201, Pharmacia and Upjohn, Kalamazoo, MI 49001, USA. Peter.G.Wuts@am.pnu.com