title: Resolution of persistent exudative retinal detachment in a case of Sturge-Weber syndrome with anti-VEGF administration.
abstract: OBJECTIVE
  Report the resolution of a persistent exudative retinal detachment in a patient with Sturge-Weber syndrome following intravitreal pegaptanib injection.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 13-year-old male with Sturge-Weber syndrome presented with a choroidal hemangioma associated with an exudative retinal detachment that failed to resolve 6 months after external beam radiation therapy.
  
  
  RESULTS
  A single intravitreal pegaptanib injection resulted in 50% resolution of the detachment within 1 week and complete resolution within a month. Despite anatomic success, vision remained poor.
  
  
  CONCLUSIONS
  VEGF likely plays a role in the pathogenesis of Sturge-Weber choroidal hemangioma-associated exudative retinal detachment and offers potential treatment.
authors: Department of Ophthalmology, Stanford University School of Medicine, Stanford, California 94305, USA.
authors: Yannis M
authors: YM
authors: Paulus
authors: Atul
authors: A
authors: Jain
authors: Darius M
authors: DM
authors: Moshfeghi
mesh_terms: D000293:Adolescent; D052157:Aptamers, Nucleotide / Q000008:administration & dosage*; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000532:radiotherapy; D005122:Exudates and Transudates / Q000378:metabolism*; D005451:Fluorescein Angiography; D006391:Hemangioma / Q000175:diagnosis / Q000209:etiology / Q000532:radiotherapy; D006801:Humans; D007267:Injections; D008297:Male; D012163:Retinal Detachment / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology* / Q000378:metabolism; D013341:Sturge-Weber Syndrome / Q000150:complications*; D016896:Treatment Outcome; D014463:Ultrasonography; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*; D014822:Vitreous Body
chemical_list: D052157:Aptamers, Nucleotide; D042461:Vascular Endothelial Growth Factor A; C495058:pegaptanib