Multiresidue determination of fluoroquinolones, organophosphorus and N-methyl carbamates simultaneously in porcine tissue using MSPD and HPLC-DAD.
Increasing concerns on public health safety have led researchers to develop efficient methods to characterize veterinary drugs and pesticides residues simultaneously in animal products. This investigation presents a simple and rapid method to determine five types of fluoroquinolones (FQs), organophosphorus (OP) and N-methyl carbamates (NMCs) in porcine tissue simultaneously with the use of matrix solid-phase dispersion (MSPD), high performance liquid chromatography (HPLC) and diode array detection (DAD). The results show a recovery ratio of 60.1-107.7% with satisfactory relative standard deviations. The limits of detection (LOD) in porcine tissue are between 9 and 22microg/kg. The applicability of the method to the multiresidue analysis in porcine tissue is reported in this contribution.
Wang
Shuting
S
Department of Chemistry, Faculty of Science, Xi'an Jiaotong University, 28 Xianning West Road, Xi'an 710049, PR China.
Mu
Hui
H
Bai
Yanhong
Y
Zhang
Yanwei
Y
Liu
Honglang
H
D000818:Animals; D002219:Carbamates / Q000032:analysis*; D005591:Chemical Fractionation / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004350:Drug Residues / Q000032:analysis; D024841:Fluoroquinolones / Q000032:analysis*; D016014:Linear Models; D008460:Meat / Q000032:analysis*; D009132:Muscles / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine; D019155:Veterinary Drugs / Q000032:analysis
D002219:Carbamates; D024841:Fluoroquinolones; D009943:Organophosphorus Compounds; D010573:Pesticide Residues; D019155:Veterinary Drugs