title: Chaotic advection in blood flow.
abstract: In this paper we argue that the effects of irregular chaotic motion of particles transported by blood can play a major role in the development of serious circulatory diseases. Vessel wall irregularities modify the flow field, changing in a nontrivial way the transport and activation of biochemically active particles. We argue that blood particle transport is often chaotic in realistic physiological conditions. We also argue that this chaotic behavior of the flow has crucial consequences for the dynamics of important processes in the blood, such as the activation of platelets which are involved in the thrombus formation.
authors: Instituto de Física, Universidade de São Paulo, Caixa Postal 66318, São Paulo 05315-970, SP, Brazil.
authors: A B
authors: AB
authors: Schelin
authors: Gy
authors: G
authors: Károlyi
authors: A P S
authors: AP
authors: de Moura
authors: N A
authors: NA
authors: Booth
authors: C
authors: C
authors: Grebogi
mesh_terms: D000818:Animals; D001692:Biological Transport; D001703:Biophysics / Q000379:methods*; D001769:Blood; D001792:Blood Platelets / Q000502:physiology; D003198:Computer Simulation; D017709:Fractals; D006439:Hemodynamics; D006801:Humans; D008954:Models, Biological; D017711:Nonlinear Dynamics; D013927:Thrombosis; D013997:Time Factors