A low-cost, linear, DC - 35 MHz, high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM).
Near-infrared (NIR) fluorescence has the potential to provide surgeons with real-time intraoperative image-guidance. Increasing the signal-to-background ratio of fluorescent agents involves delivering a controllable excitation fluence rate of proper wavelength and/or using complementary imaging techniques such as FLIM. In this study we describe a low-cost linear driver circuit capable of driving Light Emitting Diodes (LEDs) from DC to 35 MHz, at high power, and which permit fluorescence CW and lifetime measurements. The electronic circuit Gerber files described in this article and the list of components are available online at www.frangionilab.org.
Gioux
Sylvain
S
Boston University, Boston, MA.
Kianzad
Vida
V
Ciocan
Razvan
R
Choi
Hak Soo
HS
Nelson
Chad
C
Thumm
Jeffrey
J
Filkins
Robert J
RJ
Lomnes
Stephen J
SJ
Frangioni
John V
JV