An integrated view of the regulation of NKG2D ligands.
NKG2D is one of the best characterized activating receptors and is expressed on natural killer cells and on various T-cell subsets. This receptor recognizes several different ligands that are induced by cellular stresses. In this review, we described the mechanisms controlling the expression of NKG2D ligands, with the emphasis on post-transcriptional and post-translational regulation.
Stern-Ginossar
Noam
N
Lautenberg Center for General and Tumor Immunology, The Hebrew University, The BioMedical Research Institute, Hadassah Medical School, Jerusalem, Israel.
Mandelboim
Ofer
O
D058851:GPI-Linked Proteins; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000096:biosynthesis* / Q000235:genetics; D007694:Killer Cells, Natural / Q000276:immunology; D035683:MicroRNAs / Q000235:genetics; D055655:NK Cell Lectin-Like Receptor Subfamily K / Q000276:immunology; D012323:RNA Processing, Post-Transcriptional; D016176:T-Lymphocyte Subsets / Q000276:immunology
D058851:GPI-Linked Proteins; D036341:Intercellular Signaling Peptides and Proteins; C527085:KLRK1 protein, human; D035683:MicroRNAs; D055655:NK Cell Lectin-Like Receptor Subfamily K; C423230:ULBP2 protein, human
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