Tityus serrulatus scorpion venom and toxins: an overview.
Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), its long-chain Na(+)-channel toxins (NaTx), which include alpha- and beta-neurotoxins, short-chain K(+)-channel toxins (KTx), hyaluronidase, proteases and other peptides hitherto identified.
Cologna
Camila T
CT
Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-USP, Ribeirão Preto-SP, Brazil.
Marcussi
Silvana
S
Giglio
José R
JR
Soares
Andreimar M
AM
Arantes
Eliane C
EC
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008969:Molecular Sequence Data; D009498:Neurotoxins / Q000494:pharmacology; D011506:Proteins / Q000737:chemistry / Q000494:pharmacology; D012604:Scorpion Venoms / Q000737:chemistry* / Q000494:pharmacology*; D012605:Scorpions; D013020:South America
D009498:Neurotoxins; D011506:Proteins; D012604:Scorpion Venoms