title: [Increased dose of remifentanil caused difficult ventilation at emergence from general anesthesia].
abstract: Remifentanil induces a higher incidence of respiratory rigidity than other opioids, especially when it is given at bolus injection for anesthetic induction. A 71-year-old man underwent pharyngo-laryngeal surgery under general anesthesia with remifentanil and sevoflurane. At the end of surgery, the ventilation through a tracheal tube became difficult due to muscle rigidity simultaneously with the increased dose of remifentanil and the decreased sevoflurane concentration. It should be kept in mind that increased doses of remifentanil during as well as at the end of surgery cause difficult ventilation associated with muscle rigidity.
authors.affiliation: Department of Anesthesiology, Kitasato University School of Medicine, Sagamihara 228-8555.
authors.forename: Takashi
authors.initials: T
authors.lastname: Honda
authors.forename: Tamie
authors.initials: T
authors.lastname: Takenami
authors.forename: Nobuo
authors.initials: N
authors.lastname: Itou
authors.forename: Kaoruko
authors.initials: K
authors.lastname: Suzuki
authors.forename: Takashi
authors.initials: T
authors.lastname: Okamoto
authors.forename: Sumio
authors.initials: S
authors.lastname: Hoka
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects*; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008738:Methyl Ethers; D009127:Muscle Rigidity / Q000139:chemically induced*; D013517:Otorhinolaryngologic Surgical Procedures; D010880:Piperidines / Q000008:administration & dosage* / Q000009:adverse effects*; D000077208:Remifentanil; D012120:Respiration Disorders / Q000139:chemically induced*; D012132:Respiratory Muscles; D000077149:Sevoflurane
chemical_list: D000701:Analgesics, Opioid; D008738:Methyl Ethers; D010880:Piperidines; D000077149:Sevoflurane; D000077208:Remifentanil