title: WEbcoli: an interactive and asynchronous web application for in silico design and analysis of genome-scale E.coli model.
abstract: CONCLUSIONS
  WEbcoli is a WEb application for in silico designing, analyzing and engineering Escherichia coli metabolism. It is devised and implemented using advanced web technologies, thereby leading to enhanced usability and dynamic web accessibility. As a main feature, the WEbcoli system provides a user-friendly rich web interface, allowing users to virtually design and synthesize mutant strains derived from the genome-scale wild-type E.coli model and to customize pathways of interest through a graph editor. In addition, constraints-based flux analysis can be conducted for quantifying metabolic fluxes and charactering the physiological and metabolic states under various genetic and/or environmental conditions.
  
  
  BACKGROUND
  WEbcoli is freely accessible at http://webcoli.org.
  
  
  BACKGROUND
  cheld@nus.edu.sg.
authors.affiliation: Department of Information Industrial Engineering, CBITRC, Chungbuk National University, Cheongju Chungbuk 361-763, Korea.
authors.forename: Tae-Sung
authors.initials: TS
authors.lastname: Jung
authors.forename: Hock Chuan
authors.initials: HC
authors.lastname: Yeo
authors.forename: Satty G
authors.initials: SG
authors.lastname: Reddy
authors.forename: Wan-Sup
authors.initials: WS
authors.lastname: Cho
authors.forename: Dong-Yup
authors.initials: DY
authors.lastname: Lee
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D016680:Genome, Bacterial; D020407:Internet; D012984:Software