title: Emergency Department diagnosis of pulmonary embolism is associated with significantly reduced mortality: a linked data population study.
abstract: OBJECTIVE
  We characterized patients admitted via ED with a principal hospital discharge diagnosis of pulmonary embolism (PE) and compared mortality of those diagnosed in the ED with those diagnosed after admission.
  
  
  METHODS
  Patients with a hospital discharge diagnosis ICD 10 I26 presenting to the ED in Perth, Western Australia between 1 July 2000 and 30 December 2006 had records from the Emergency Department Information System linked to the Western Australian Hospital Morbidity Data System and the death registry.
  
  
  RESULTS
  Of 2250 patients (mean age 60.4), 1227 (54.5%) were female. Of 1931 patients with an ED diagnosis recorded, 1207 (62.5%) were diagnosed with PE in ED. Of these, 383 (17.0%) had presented to an ED within 28 days previously, 142 (37.1%) with either chest pain or breathing problems, with 207 (54.0%) admitted but not receiving a principal hospital discharge diagnosis of PE. There were 127 (5.6%) in-hospital deaths. Controlling for age and comorbidity with logistic regression, patients diagnosed with PE in ED were less likely to die in hospital, within 7 and 30 days of ED arrival, than those diagnosed after admission (adjusted OR 0.31, 95% CI 0.20-0.47; adjusted OR 0.32, 95% CI 0.19-0.53; adjusted OR 0.30, 95% CI 0.20-0.44; respectively).
  
  
  CONCLUSIONS
  Making the diagnosis of PE in ED was associated with a substantial survival advantage that persisted after hospital discharge.
authors.affiliation: Discipline of Emergency Medicine, University of Western Australia, Western Australia, Australia. george.Jelinek@gmail.com
authors.forename: George A
authors.initials: GA
authors.lastname: Jelinek
authors.forename: Sharyn L
authors.initials: SL
authors.lastname: Ingarfield
authors.forename: David
authors.initials: D
authors.lastname: Mountain
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Gibson
authors.forename: Ian G
authors.initials: IG
authors.lastname: Jacobs
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002985:Clinical Protocols; D015331:Cohort Studies; D004636:Emergency Service, Hospital; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010343:Patient Admission / Q000706:statistics & numerical data; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000401:mortality*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014904:Western Australia / Q000453:epidemiology; D055815:Young Adult