title: Transthoracic fine-needle aspiration in the aetiological diagnosis of community-acquired pneumonia.
abstract: To investigate the safety and practicability of conducting transthoracic fine-needle aspiration (TFNA) in a general hospital setting, we applied the TFNA procedure to 20 patients hospitalized with community-acquired pneumonia (CAP) within 36 h of admission. Also, a preliminary assessment was made of the potential value of adding TFNA to conventional methods of diagnostic microbiology. TFNA was easy to perform and caused little discomfort, and no serious adverse events were observed. In spite of ongoing antimicrobial treatment, a likely aetiological diagnosis was established for 14 of 20 (70%) of the patients. TFNA may provide important additional information on the aetiology of CAP.
authors.affiliation: Department of Geriatrics and Internal Medicine, Sorlandet Hospital Arendal HF, Arendal, Norway. drhernes@gmail.com
authors.forename: S S
authors.initials: SS
authors.lastname: Hernes
authors.forename: E
authors.initials: E
authors.lastname: Hagen
authors.forename: S
authors.initials: S
authors.lastname: Tofteland
authors.forename: N T
authors.initials: NT
authors.lastname: Finsen
authors.forename: A
authors.initials: A
authors.lastname: Christensen
authors.forename: C G
authors.initials: CG
authors.lastname: Giske
authors.forename: C
authors.initials: C
authors.lastname: Spindler
authors.forename: P S
authors.initials: PS
authors.lastname: Bakke
authors.forename: B
authors.initials: B
authors.lastname: Bjorvatn
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle / Q000009:adverse effects / Q000379:methods; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000382:microbiology; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D008875:Middle Aged; D001936:Moraxella catarrhalis / Q000302:isolation & purification; D010865:Pilot Projects; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000382:microbiology; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D055815:Young Adult
chemical_list: D012336:RNA, Ribosomal, 16S
references.citation: Clin Infect Dis. 2002 Mar 1;34(5):583-90
references.pmid: 11803504
references.citation: Diagn Microbiol Infect Dis. 2006 Jul;55(3):169-78
references.pmid: 16626914
references.citation: Am J Med. 1999 Apr;106(4):385-90
references.pmid: 10225239
references.citation: Chest. 1999 Dec;116(6):1716-32
references.pmid: 10593800
references.citation: J Clin Microbiol. 1999 Mar;37(3):709-14
references.pmid: 9986837
references.citation: Diagn Microbiol Infect Dis. 2008 Feb;60(2):143-50
references.pmid: 17916422
references.citation: Clin Infect Dis. 2001 Mar 1;32(5):715-26
references.pmid: 11229839
references.citation: JAMA. 1976 Jan 12;235(2):158-63
references.pmid: 521