Recurrent hemoptysis with Penicillium marneffei and Stenotrophomonas maltophilia in Job's syndrome.
Pulmonary infection caused by the opportunistic organisms Penicillium marneffei and Stenotrophomonas maltophilia in patients with Job's syndrome is rare and not well documented. The case of a 30-year-old man with Job's syndrome who developed recurrent pneumonia and lung abscesses caused by P. marneffei and S. maltophilia, complicated by massive hemoptysis, is described. Bronchial artery embolization was successful in controlling the hemoptysis; however, the infection proved fatal despite appropriate antimicrobial therapy. A brief review of the literature on Job's syndrome and its associated infective pulmonary manifestations is also presented.
Ma
Bosco H M
BH
Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Ng
Calvin S H
CS
Lam
Rebecca  K Y
R
Wan
Song
S
Wan
Innes Y P
IY
Lee
Tak Wai
TW
Yim
Anthony P C
AP
D000328:Adult; D016905:Gram-Negative Bacterial Infections / Q000150:complications*; D006469:Hemoptysis / Q000382:microbiology*; D006801:Humans; D007589:Job Syndrome / Q000150:complications / Q000382:microbiology*; D008172:Lung Diseases, Fungal / Q000150:complications*; D008297:Male; D010407:Penicillium / Q000302:isolation & purification*; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*
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