title: Smoking and drinking in relation to depressive symptoms among persons with oral cancer or oral epithelial dysplasia.
abstract: BACKGROUND
  We examined whether smoking or drinking during or before the diagnosis-year of oral cancer or oral epithelial dysplasia (OED) was related to "subsequent depression" measured months after the oral diagnosis.
  
  
  METHODS
  Incident cases of oral cancer or OED were identified via 3 oral pathology laboratories. A telephone-administered questionnaire included questions on smoking/drinking history through the diagnosis-year and measured depressive symptoms using the Center for Epidemiologic Studies-Depression Scale (CES-D); scores of 16+ indicated clinical depression. "Subsequent depression" was defined as a CES-D score of 16+, measured at the time of assessment several months after the diagnosis of oral cancer or OED.
  
  
  RESULTS
  Patients who smoked during their diagnosis-year had twice the odds of subsequent depression relative to former/never smokers. Diagnosis-year (vs never/former) drinking was not associated with depression; however, average alcohol consumption of >1.5 drinks/week was negatively associated with subsequent depression for both diagnosis-year and ex-drinkers (past reported drinking) even among heavy drinkers.
  
  
  CONCLUSIONS
  Our findings suggest that subsequent depression is positively associated with diagnosis-year smoking and negatively associated with alcohol consumption of >1.5 drinks/week among both diagnosis-year and ex-drinkers.
authors.affiliation: New York University College of Dentistry, Department of Epidemiology & Health Promotion, New York, NY 10003, USA. dem5@nyu.edu
authors.forename: Douglas E
authors.initials: DE
authors.lastname: Morse
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Psoter
authors.forename: Linda S
authors.initials: LS
authors.lastname: Baek
authors.forename: Ellen
authors.initials: E
authors.lastname: Eisenberg
authors.forename: Donald
authors.initials: D
authors.lastname: Cohen
authors.forename: Deborah
authors.initials: D
authors.lastname: Cleveland
authors.forename: Mirseyed
authors.initials: M
authors.lastname: Mohit-Tabatabai
authors.forename: Susan
authors.initials: S
authors.lastname: Reisine
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology*; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000453:epidemiology*; D011230:Precancerous Conditions / Q000453:epidemiology*; D012907:Smoking / Q000453:epidemiology*; D011795:Surveys and Questionnaires
references.citation: Cancer Epidemiol Biomarkers Prev. 1996 Oct;5(10):769-77
references.pmid: 8896887
references.citation: Psychooncology. 2004 Apr;13(4):269-80
references.pmid: 15054731
references.citation: Int J Addict. 1994 Apr;29(5):609-26
references.pmid: 8034375
references.citation: Psychooncology. 1999 Nov-Dec;8(6):494-9
references.pmid: 10607982
references.citation: Cancer Causes Control. 2007 Nov;18(9):919-29
references.pmid: 17647085
references.citation: JAMA. 1990 Sep 26;264(12):1541-5
references.pmid: 2395193
references.citation: Drug Alcohol Depend. 2002 Dec 1;68(3):299-307
references.pmid: 12393224
references.citation: Psychol Rep. 2003 Apr;92(2):529-32
references.pmid: 12785636
references.citation: Ann Behav Med. 2003 Aug;26(1):24-31
references.pmid: 12867351
references.citation: Psychol Med. 2000 Mar;30(2):421-32
references.pmid: 10824662
references.citation: Int J Cancer. 2004 Feb 20;108(5):741-9
references.pmid: 14696101
references.citation: Br J Psychiatry. 2008 Oct;193(4):322-6
references.pmid: 18827296
references.citation: Drug Alcohol Depend. 1995 Oct;39(3):197-206
references.pmid: 8556968
references.citation: Gen Hosp Psychiatry. 2002 May-Jun;24(3):140-7
references.pmid: 12062138
references.citation: Drug Alcohol Depend. 2001 Aug 1;63(3):277-86
references.pmid: 11418232
references.citation: Addiction. 2002 May;97(5):583-94
references.pmid: 12033659
references.citation: Br J Oral Maxillofac Surg. 2001 Oct;39(5):333-9
references.pmid: 11601810
references.citation: Am J Public Health. 1990 Dec;80(12):1500-2
references.pmid: 2240340
references.citation: Compr Psychiatry. 1998 Jul-Aug;39(4):176-84
references.pmid: 9675501
references.citation: Asia Pac J Public Health. 1999;11(2):60-4
references.pmid: 11195159
references.citation: J Oral Maxillofac Surg. 2005 Apr;63(4):513-20
references.pmid: 15789324
references.citation: Behav Med. 1997 Fall;23(3):101-11
references.pmid: 9397282
references.citation: J Oral Maxillofac Surg. 2003 Mar;61(3):285-91
references.pmid: 12618965
references.citation: Am J Med Sci. 2003 Oct;326(4):187-91
references.pmid: 14557732
references.citation: Oral Oncol. 2002 Jan;38(1):81-6
references.pmid: 11755825
references.citation: Am J Epidemiol. 1979 Feb;109(2):186-204
references.pmid: 425958
references.citation: Cancer Causes Control. 1999 Feb;10(1):27-33
references.pmid: 10334639
references.citation: Arch Otolaryngol Head Neck Surg. 2008 Mar;134(3):241-8
references.pmid: 18347247
references.citation: Psychosomatics. 2007 Mar-Apr;48(2):142-8
references.pmid: 17329608
references.citation: Addict Behav. 2003 Apr;28(3):575-82
references.pmid: 12628628
references.citation: Psychooncology. 2000 Jan-Feb;9(1):20-8
references.pmid: 10668056
references.citation: Head Neck. 2001 Oct;23(10):892-8
references.pmid: 11592237
references.citation: Head Neck. 2003 Feb;25(2):103-12
references.pmid: 12509792
references.citation: Psychosomatics. 1997 Mar-Apr;38(2):132-9
references.pmid: 9063044
references.citation: JAMA. 1990 Sep 26;264(12):1546-9
references.pmid: 2395194
references.citation: Cancer Res. 1988 Jun 1;48(11):3282-7
references.pmid: 3365707
references.citation: Am J Public Health. 1994 Dec;84(12):1913-7
references.pmid: 7998629