title: Oncogenic K-ras "addiction" and synthetic lethality.
authors.forename: Anurag
authors.initials: A
authors.lastname: Singh
authors.forename: Jeff
authors.initials: J
authors.lastname: Settleman
mesh_terms: D017209:Apoptosis; D018797:Cell Cycle Proteins / Q000378:metabolism; D011905:Genes, ras; D006801:Humans; D039641:Integrin beta Chains / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D009154:Mutation; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics / Q000378:metabolism*; D034622:RNA Interference; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism; D000072377:Syk Kinase; D000097869:Polo-Like Kinase 1
chemical_list: D018797:Cell Cycle Proteins; D039641:Integrin beta Chains; D047908:Intracellular Signaling Peptides and Proteins; D017346:Protein Serine-Threonine Kinases; D011505:Protein-Tyrosine Kinases; D011518:Proto-Oncogene Proteins; D016283:Proto-Oncogene Proteins p21(ras); D020794:Receptor Protein-Tyrosine Kinases; D000072377:Syk Kinase; D000097869:Polo-Like Kinase 1; C072170:integrin beta6; C080835:RON protein; C000606896:SYK protein, human; C505233:STK33 protein, human
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