title: Effects of infrared radiation and heat on human skin aging in vivo.
abstract: Sunlight damages human skin, resulting in a wrinkled appearance. Since natural sunlight is polychromatic, its ultimate effects on the human skin are the result of not only the action of each wavelength separately, but also interactions among the many wavelengths, including UV, visible light, and infrared (IR). In direct sunlight, the temperature of human skin rises to about 40 degrees C following the conversion of absorbed IR into heat. So far, our knowledge of the effects of IR radiation or heat on skin aging is limited. Recent work demonstrates that IR and heat exposure each induces cutaneous angiogenesis and inflammatory cellular infiltration, disrupts the dermal extracellular matrix by inducing matrix metalloproteinases, and alters dermal structural proteins, thereby adding to premature skin aging. This review provides a summary of current research on the effects of IR radiation and heat on aging in human skin in vivo.Journal of Investigative Dermatology Symposium Proceedings (2009) 14, 15-19; doi:10.1038/jidsymp.2009.7.
authors.affiliation: Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Soyun
authors.initials: S
authors.lastname: Cho
authors.forename: Mi Hee
authors.initials: MH
authors.lastname: Shin
authors.forename: Yeon Kyung
authors.initials: YK
authors.lastname: Kim
authors.forename: Jo-Eun
authors.initials: JE
authors.lastname: Seo
authors.forename: Young Mee
authors.initials: YM
authors.lastname: Lee
authors.forename: Chi-Hyun
authors.initials: CH
authors.lastname: Park
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Chung
mesh_terms: D003094:Collagen / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D004249:DNA Damage; D000071837:Fibrillins; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D007259:Infrared Rays / Q000009:adverse effects; D015603:Keratinocytes / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D020782:Matrix Metalloproteinases / Q000378:metabolism; D008840:Microfilament Proteins / Q000378:metabolism; D009389:Neovascularization, Pathologic / Q000209:etiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D012867:Skin / Q000098:blood supply / Q000293:injuries / Q000378:metabolism / Q000528:radiation effects; D015595:Skin Aging / Q000502:physiology / Q000528:radiation effects*; D050916:TRPV Cation Channels / Q000378:metabolism; D014333:Tropoelastin / Q000378:metabolism; D053802:Tryptases / Q000378:metabolism
chemical_list: D016207:Cytokines; D000071837:Fibrillins; D008840:Microfilament Proteins; D017382:Reactive Oxygen Species; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; D014333:Tropoelastin; D003094:Collagen; D053802:Tryptases; D020782:Matrix Metalloproteinases