title: Cytologic diagnosis of vulvar Paget's disease by means of brushing smear: report of a case.
abstract: Paget's disease of the vulva is a rare entity; since it may show the same clinical symptoms as benign chronic vulvitis, it may result in a delayed diagnosis. A 63-year-old woman was found to have an eczematoid pink to red lesion located in the vulva. Scraping cytology of the vulva showed isolated malignant cells of Paget type. The patient underwent wide local excision of the vulvar tumor and histopathological examination of resected specimens revealed that Paget cells were distributed singly or tended to form small nests in the epidermis. We consider vigorous brushing cytology to be a useful initial study for cancer screening of patients for any suspicious vulvar lesions.
authors.affiliation: Department of Diagnostic Pathology, Kagawa University Hospital, Kagawa, Japan.
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Funamoto
authors.forename: Reiji
authors.initials: R
authors.lastname: Haba
authors.forename: Tadao K
authors.initials: TK
authors.lastname: Kobayashi
authors.forename: Yosio
authors.initials: Y
authors.lastname: Kushida
authors.forename: Kouji
authors.initials: K
authors.lastname: Kouno
authors.forename: Toru
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Atuko
authors.initials: A
authors.lastname: Shiota
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Hata
mesh_terms: D001706:Biopsy / Q000379:methods*; D057210:Delayed Diagnosis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000601:surgery; D010145:Paget Disease, Extramammary / Q000175:diagnosis* / Q000601:surgery; D014626:Vaginal Smears; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000601:surgery