title: Combination of 308-nm excimer laser with topical pimecrolimus for the treatment of childhood vitiligo.
abstract: Forty-nine patients enrolled in a single-blinded, randomized, comparing 308-nm excimer laser therapy together with topical 1% pimecrolimus cream twice daily (group A) with excimer laser therapy twice per week (group B). Of 48 patients evaluated after 30 weeks of treatment, 71% of patients from group A achieved Grade 3 or 4 repigmentation compared with 50% in group B. Significant difference was found between group A and B at the end of 30 weeks of treatment (p = 0.001).
authors.affiliation: Department of Dermatology, Liu Hua Qiao Hospital, Guangzhou, China. huilany88@hotmail.com
authors.forename: Yang
authors.initials: Y
authors.lastname: Hui-Lan
authors.forename: Huang
authors.initials: H
authors.lastname: Xiao-Yan
authors.forename: Fan
authors.initials: F
authors.lastname: Jian-Yong
authors.forename: Liu
authors.initials: L
authors.lastname: Zong-Rong
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D002648:Child; D003131:Combined Modality Therapy; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D054018:Lasers, Excimer / Q000009:adverse effects / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000009:adverse effects; D008297:Male; D016037:Single-Blind Method; D012880:Skin Pigmentation; D016559:Tacrolimus / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D014820:Vitiligo / Q000628:therapy*
chemical_list: D003879:Dermatologic Agents; C117268:pimecrolimus; D016559:Tacrolimus