Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy.
OBJECTIVE
In this study, the effects of intravenous paracetamol treatment on early postoperative period analgesia and recovery characteristics after laparoscopic cholecystectomy have been evaluated.


METHODS
Forty patients whose American Society of Anesthesiologists physical status I or II underwent laparoscopic cholecystectomy and randomly divided into 2 equal groups. In the first group, 1 g paracetamol was given to the patients intravenously after intubation before start of the surgery in 15 minutes. The 100 mL 0.9% NaCl was infused intravenously for the control group in 15 minutes. Postoperative pain was evaluated and recovery characteristics were evaluated.


RESULTS
Verbal and visual pain scores of the paracetamol group were significantly lower than control group (P<0.05). First morphine requirement and total administered morphine dose and duration of staying in recovery room were significantly decreased in the paracetamol group (P<0.05).


CONCLUSIONS
Beside its effective analgesic properties, paracetamol administration during per operative period supports effective and faster recovery.
Salihoglu
Ziya
Z
Department of Anesthesiology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
Yildirim
Murat
M
Demiroluk
Sener
S
Kaya
Guner
G
Karatas
Adem
A
Ertem
Metin
M
Aytac
Erman
E
D000082:Acetaminophen / Q000008:administration & dosage*; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D017081:Cholecystectomy, Laparoscopic; D006801:Humans; D007262:Infusions, Intravenous; D010149:Postoperative Pain / Q000188:drug therapy*; D020127:Recovery of Function
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen