title: Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range.
abstract: We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber angle and the cornea. The speed of 200,000 lines/s enables high sampling density in three-dimensional imaging of the entire cornea in 250 ms promising future applications of OCT for optical corneal topography, pachymetry and elevation maps. The results of a preliminary quantitative corneal analysis based on OCT data free form motion artifacts are presented. Additionally, a volumetric and real time reconstruction of dynamic processes, like pupillary reaction to light stimulus or blink-induced contact lens movements are demonstrated.
authors.affiliation: Institute of Physics, Nicolaus Copernicus University, ul. Grudziadzka 5/7, PL-87-100 Toruń, Poland.
authors.forename: Michalina
authors.initials: M
authors.lastname: Gora
authors.forename: Karol
authors.initials: K
authors.lastname: Karnowski
authors.forename: Maciej
authors.initials: M
authors.lastname: Szkulmowski
authors.forename: Bartlomiej J
authors.initials: BJ
authors.lastname: Kaluzny
authors.forename: Robert
authors.initials: R
authors.lastname: Huber
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kowalczyk
authors.forename: Maciej
authors.initials: M
authors.lastname: Wojtkowski
mesh_terms: D016477:Artifacts; D003315:Cornea / Q000033:anatomy & histology; D019781:Corneal Topography / Q000379:methods; D003952:Diagnostic Imaging / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D005123:Eye / Q000033:anatomy & histology* / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis* / Q000473:pathology; D005583:Fourier Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D007834:Lasers; D009038:Motion; D009885:Ophthalmology / Q000379:methods; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods