title: Can the protein occupancy landscape show the topologically isolated chromosomal domains in the E. coli genome?: An exciting prospect.
abstract: In a recent issue of Molecular Cell, Vora et al. (2009) introduce an in vivo protein occupancy display (IPOD) technology and propose that the domains extensively occupied by proteins with inactive transcription in bacteria are mainly topologically isolated chromosomal domains.
authors.affiliation: Department of Bioengineering, University of California, San Diego, La Jolla, 92093, USA.
authors.forename: Byung-Kwan
authors.initials: BK
authors.lastname: Cho
authors.forename: Bernhard Ø
authors.initials: BØ
authors.lastname: Palsson
mesh_terms: D001665:Binding Sites; D047369:Chromatin Immunoprecipitation; D002876:Chromosomes, Bacterial / Q000737:chemistry / Q000378:metabolism*; D018983:DNA Footprinting; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D016680:Genome, Bacterial
chemical_list: D029968:Escherichia coli Proteins