title: Congenital disseminated pyogenic granuloma.
abstract: In the past pyogenic granuloma (PG) in infancy has been easily confused clinically and histopathologically with infantile hemangioma (IH). In 2000 North and colleagues discovered that IH is immunopositive for GLUT-1, a glucose transporter which is also expressed in placental capillaries (1). GLUT-1 staining is negative in pyogenic granuloma. We report two newborns with congenital disseminated PG who were otherwise healthy. In both of these cases, negative GLUT-1 staining supported the proper diagnosis.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, TX77030, USA. JohnBrowningMD@yahoo.com
authors.forename: John C
authors.initials: JC
authors.lastname: Browning
authors.forename: Karen W
authors.initials: KW
authors.lastname: Eldin
authors.forename: Harry P W
authors.initials: HP
authors.lastname: Kozakewich
authors.forename: John B
authors.initials: JB
authors.lastname: Mulliken
authors.forename: Alanna F
authors.initials: AF
authors.lastname: Bree
mesh_terms: D005260:Female; D017789:Granuloma, Pyogenic / Q000151:congenital* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male