title: [Expression of tryptase and chymase in human lung tissue of anaphylactic shock].
abstract: OBJECTIVE
  To explore the expression of tryptase and chymase in human lung tissue of anaphylactic shock and its value for forensic medicine.
  
  
  METHODS
  With ten carbon monoxide poisoning cases as control group, the levels of tryptase and chymase were observed by immunofluorescence and analyzed using the Image Analyze and the Image-pro plus 5.0.2. The positive mast cells were counted and the levels of the tryptase and chymase were calculated respectively.
  
  
  RESULTS
  There was a statistically significant difference (P < 0.05) for the tryptase and chymase concentrations in the lung tissue between the anaphylactic shock group and the control group.
  
  
  CONCLUSIONS
  The levels of the tryptase and the chymase expression are greatly increased in human lung tissue of anaphylactic shock, which may provide the morphological evidence and reference for the diagnosis of anaphylactic shock in forensic practice.
authors.affiliation: Department of Forensic Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
authors.forename: Zhi-Yan
authors.initials: ZY
authors.lastname: Wei
authors.forename: Cai-Rong
authors.initials: CR
authors.lastname: Gao
authors.forename: Ming
authors.initials: M
authors.lastname: Pei
mesh_terms: D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000201:enzymology* / Q000473:pathology; D002102:Cadaver; D002249:Carbon Monoxide Poisoning / Q000201:enzymology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D053818:Chymases / Q000378:metabolism*; D005260:Female; D015200:Fluoroimmunoassay / Q000379:methods; D049429:Forensic Pathology; D006801:Humans; D007223:Infant; D008168:Lung / Q000201:enzymology* / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000201:enzymology*; D008875:Middle Aged; D013194:Staining and Labeling; D053802:Tryptases / Q000378:metabolism*; D055815:Young Adult
chemical_list: D053818:Chymases; D053802:Tryptases