[Treatment of focal bone defect in postoperative nonunion with autologous red bone marrow injection].
OBJECTIVE
To observe the clinical effect of autologous red bone marrow injection in treating focal bone defect in postoperative nonunion.


METHODS
Thirteen patients with focal bone defect in postoperative nonunion (7 cases in tibia, 2 cases in femur, 4 cases in humerus), including 8 males and 5 females with the mean age of 32.5-years-old (ranging from 15 to 60 years). The bone defects were treated with autologous red bone marrow injection (1 time per 2 weeks, 5 times in total) and the X-rays of AP and LP were observed.


RESULTS
Thirteen patients were followed up from 6 to 12 months with an average of 7.5 months. According to results of X-ray pictures, 13 cases obtained bone defect recovered completely, and the average time of union was 4 months.


CONCLUSIONS
Autologous red bone marrow injection has ascendancy such as less wound and clear clinical effect, which can accelerate bone healing and promotes functional recovery of limb. It is a good method to treat focal bone defect in postoperative nonunion.
Tang
Zhao-hui
ZH
The 16th Hospital of PLA, Aletai 836500, Xinjiang, China.
Zhu
Li-xing
LX
Xu
Tu-bing
TB
Wang
Kai
K
Zhou
Xin-min
XM
Li
Qiang
Q
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D001861:Bone Regeneration; D001842:Bone and Bones / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000628:therapy*; D014182:Transplantation, Autologous; D055815:Young Adult