It's all in the details: methods in breast development and cancer.
The inaugural European Network for Breast Development and Cancer (ENBDC) meeting on 'Methods in Mammary Gland Development and Cancer' was held in Weggis, Switzerland last April. The goal was to discuss the details of techniques used to study mammary gland biology and tumourigenesis. Highlights of this meeting included the use of four-colour fluorescence for protein co-localisation in tissue microarrays, genome analysis at single cell resolution, technical issues in the isolation of normal and tumour stem cells, and the use of mouse models and mammary gland transplantations to elucidate gene function in mammary development and to study drug resistance in breast cancer.
Bentires-Alj
Mohamed
M
Friedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstr, 66; CH-4058 Basel, Switzerland. Bentires@fmi.ch
Clarke
Robert B
RB
Jonkers
Jos
J
Smalley
Matthew
M
Stein
Torsten
T
D000818:Animals; D001940:Breast / Q000166:cytology / Q000254:growth & development*; D001943:Breast Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D019008:Drug Resistance, Neoplasm; D004847:Epithelial Cells / Q000166:cytology; D005260:Female; D005813:Genes, Synthetic; D006651:Histocytochemistry / Q000379:methods*; D006801:Humans; D053569:Keratin-15; D053555:Keratin-5 / Q000235:genetics; D008325:Mammary Neoplasms, Experimental / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology; D008495:Medical Oncology / Q000379:methods*; D051379:Mice; D018613:Microscopy, Confocal / Q000379:methods; D008856:Microscopy, Fluorescence / Q000379:methods; D014411:Neoplastic Stem Cells / Q000737:chemistry / Q000648:ultrastructure; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D010338:Pathology, Clinical / Q000379:methods*; D011401:Promoter Regions, Genetic; D013234:Stem Cells / Q000166:cytology
D053569:Keratin-15; D053555:Keratin-5; C492053:Krt15 protein, mouse
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