title: Amoxicillin-clavulanic acid-induced linear immunoglobulin A bullous dermatosis: case report and review of the literature.
abstract: BACKGROUND
  Linear immunoglobulin A bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease, rarely induced by drugs.
  
  
  METHODS
  We describe a case of a 47-year-old man who developed a severe blistering eruption after therapy with amoxicillin-clavulanic acid.
  
  
  RESULTS
  Histopathologic examination and direct immunofluorescence were consistent with a diagnosis of LABD. Therapy with dapsone controlled the disease but, after sun exposure, there was a worsening of the illness.
  
  
  CONCLUSIONS
  To our knowledge, this is the first case of amoxicillin-clavulanic acid-induced LABD in an adult.
authors.affiliation: Department of Dermatology, University of Rome La Sapienza, Rome, Italy. ilcapo75@gmx.net
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Panasiti
authors.forename: Mariarita
authors.initials: M
authors.lastname: Rossi
authors.forename: Valeria
authors.initials: V
authors.lastname: Devirgiliis
authors.forename: Michela
authors.initials: M
authors.lastname: Curzio
authors.forename: Ugo
authors.initials: U
authors.lastname: Bottoni
authors.forename: Stefano
authors.initials: S
authors.lastname: Calvieri
mesh_terms: D019980:Amoxicillin-Potassium Clavulanate Combination / Q000009:adverse effects*; D006801:Humans; D007070:Immunoglobulin A; D008297:Male; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000276:immunology*
chemical_list: D007070:Immunoglobulin A; D019980:Amoxicillin-Potassium Clavulanate Combination