A novel uni-acupoint electroacupuncture stimulation method for pain relief.
Electroacupuncture stimulation (EAS) has been demonstrated effective for pain relief and treating other various diseases. However, the conventional way of EAS, the bi-acupoint method, is not suitable for basis study of acupoint specificity. Moreover, its operations are inconvenient and difficult to be persevered, especially for long-term, continuous and even imperative treatments. These disadvantages motivate designs of new EAS methods. We present a novel uni-acupoint electrical stimulation method, which is applied at a single acupoint and quite meets the needs of basis study and simpler clinical application. Its pain relief effect has been evaluated by animal tests of Wistar rats. During the experiments, rats were given 30 min 2/100 Hz uni- and bi-acupoint EAS and their nociceptive thresholds before and after EAS were attained by hot-plate test. The analgesic effect was defined as the change of nociceptive threshold and used to evaluate the effectiveness of uni-acupoint EAS for pain relief. The hot-plate test results indicated that analgesic effect of uni-acupoint group was significantly higher than that of the control group and there was no significant difference of analgesic effects between uni- and bi-acupoint EAS. The results suggested that uni-acupoint method was an effective EAS method and had comparable pain relief effect with bi-acupoint method.
Niu
Chuansen
C
Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Hao
Hongwei
H
Lu
Jun
J
Li
Luming
L
Han
Zhirong
Z
Tu
Ya
Y
Brain Res. 1999 Dec 18;851(1-2):290-6
10642860
Brain Res. 2005 May 24;1044(2):155-63
15885214
Evid Based Complement Alternat Med. 2008 Sep;5(3):257-66
18830420
Pain. 2006 May;122(1-2):81-9
16527396
Neurosci Lett. 2004 May 6;361(1-3):258-61
15135942
NIH Consens Statement. 1997 Nov 3-5;15(5):1-34
10228456
Hum Psychopharmacol. 2002 Oct;17(7):345-8
12415553
Pain. 2001 Mar;91(1-2):5-13
11240073
Neuroimage. 2002 Aug;16(4):1028-37
12202090
Pain. 2004 Jun;109(3):299-307
15157691
JAMA. 1999 Mar 3;281(9):818-23
10071003
Neurochem Res. 2008 Oct;33(10):2107-11
18461444
Acta Histochem. 2005;107(1):67-76
15866287
Nature. 1999 Apr 29;398(6730):805-10
10235262
Evid Based Complement Alternat Med. 2007 Mar;4(1):125-30
17342250
Neurosci Lett. 2004 Jan 2;354(1):50-3
14698480
Neurosci Lett. 2001 Jul 13;307(2):105-8
11427311
Biol Psychiatry. 1998 Jul 15;44(2):129-38
9646895
Pain. 2002 Oct;99(3):509-514
12406527
Trends Neurosci. 2003 Jan;26(1):17-22
12495858
Med Eng Phys. 2003 Apr;25(3):239-53
12589722
Int J Neurosci. 2006 Feb;116(2):115-25
16393878
Exp Neurol. 2005 Mar;192(1):156-62
15698629