title: New objective evaluation method for functional bowel disorder using video capsule endoscopy.
abstract: OBJECTIVE
  The aim of the present study was to use video capsule endoscopy (VCE) to objectively evaluate bowel movements in patients with irritable bowel syndrome (IBS) compared with healthy volunteers.
  
  
  METHODS
  Subjects were nine healthy volunteers (group A) and five IBS patients (group B) whose VCE reached the cecum within the examination time. As the darkest component in an image of VCE is the lumen, we regarded real movements of the intestine observed in the images as the changes of luminal movement, and analyzed them. We trimmed the luminal edge, counted pixels in the lumen and the low brightness area (LBA), of all VCE images and compared them between the groups.
  
  
  RESULTS
  There was no difference in the frequency observed in the LBA corresponding to the luminal area between the groups. As for the average volume of the LBA found in an image, it was 1702 pixels in healthy persons versus 305 in IBS patients (P = 0.21) and in healthy persons it tends to be larger. We drew a graph of LBA by time-course. A periodic change in the volume of LBA was found in eight of nine (88.9%) healthy persons over time, but in only two of five (40.0%) IBS patients (P = 0.62). Using endoscopy, a difference in the bowel movement between groups A and B could be evaluated objectively.
  
  
  CONCLUSIONS
  The present study presents the possibility of a new technique to evaluate functional bowel disorders objectively using an endoscopic procedure.
authors.affiliation: Department of Gastroenterology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
authors.forename: Masanao
authors.initials: M
authors.lastname: Nakamura
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Niwa
authors.forename: Makoto
authors.initials: M
authors.lastname: Yagihashi
authors.forename: Naoki
authors.initials: N
authors.lastname: Ohmiya
authors.forename: Ryoji
authors.initials: R
authors.lastname: Miyahara
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ando
authors.forename: Osamu
authors.initials: O
authors.lastname: Watanabe
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kawashima
authors.forename: Akihiro
authors.initials: A
authors.lastname: Itoh
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Hirooka
authors.forename: Hideo
authors.initials: H
authors.lastname: Fujimoto
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto
mesh_terms: D000328:Adult; D053704:Capsule Endoscopy; D003672:Defecation; D006801:Humans; D043183:Irritable Bowel Syndrome