The management of spinal metastases from renal cell carcinoma.
BACKGROUND
Osseous metastases occur in 50% of patients with renal cell carcinoma; of these, 15% occur in the spine. The treatment options for spinal metastases secondary to renal cell carcinoma are limited. This paper considers the current management options available for spinal metastases secondary to renal cell carcinoma.


METHODS
A review of four patients with spinal metastases secondary to renal cell carcinoma.


RESULTS
The presentation of four cases highlighting the current management options for spinal metastases secondary to renal cell carcinoma.


CONCLUSIONS
Historically, spinal metastases from renal cell carcinoma have been poorly managed; however, as the treatment of the primary disease improves, better treatment of the secondary disease is needed. Cement augmentation, used alone for prophylactic stabilisation or in conjunction with a posterior decompression and fixation, provides a useful addition in the management of these patients optimising their chance to remain ambulant, continent, and pain-free.
Langdon
James
J
Specialist Registrar in Trauma and Orthopaedics, The Spinal Deformity Unit, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore HA7 4LP, UK. jmplangdon@googlemail.com
Way
Adam
A
Heaton
Samuel
S
Bernard
Jason
J
Molloy
Sean
S
D000368:Aged; D001843:Bone Cements; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D019299:Decompression, Surgical / Q000379:methods; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008159:Lumbar Vertebrae / Q000293:injuries; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000601:surgery; D019904:Polymethyl Methacrylate; D011859:Radiography; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000293:injuries; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods
D001843:Bone Cements; D019904:Polymethyl Methacrylate
Acta Orthop Scand Suppl. 2001 Jun;72(302):2p., 1-29
11582636
Urology. 1981 Dec;18(6):556-61
7314355
Lancet. 2005 Aug 20-26;366(9486):643-8
16112300
Clin Orthop Relat Res. 2001 Sep;(390):206-11
11550867
Spine (Phila Pa 1976). 2003 Jul 15;28(14):1549-54
12865843
Spine (Phila Pa 1976). 2001 Jan 15;26(2):151-6
11154534
Spine (Phila Pa 1976). 1983 Nov-Dec;8(8):817-31
6670016
Cancer. 1997 Sep 15;80(6):1103-9
9305711
Eur Spine J. 2005 Apr;14(3):250-60
15480827
J Urol. 1992 Sep;148(3):784-7
1512825
J Urol. 1986 Aug;136(2):376-9
3735498
Cancer. 1981 Sep 15;48(6):1487-91
7272969
Acta Radiol. 2007 Feb;48(1):89-95
17325932
Int Orthop. 1994 Oct;18(5):291-8
7852009
Spine (Phila Pa 1976). 2001 Feb 1;26(3):298-306
11224867
Am J Clin Oncol. 1997 Aug;20(4):416-8
9256902