Congenital neuroblastoma with liver metastasis presenting with Hashimoto Pritzker disease.
A two-month-old female child presented with discrete skin-colored papules on the forehead and scalp. She was earlier diagnosed to have neuroblastoma of the adrenal gland which had metastasized to the liver. Histological sections of the skin lesion showed a nodule composed of sheets of cells with abundant eosinophilic cytoplasm and an occasional grooving of the nucleus. These cells were CD 68 positive. Eosinophilic abscesses were seen in between the neoplastic cells.
Jacob
E Sajini
ES
Department of Pathology, Pondicherry Institute of Medical Sciences, Kalapet, Puducherry, India. sajinijac@yahoo.com
Varghese
Renu G
RG
Toi
Pampa C
PC
Bhaskaran
R
R
Rai
Ramji
R
D000310:Adrenal Gland Neoplasms / Q000473:pathology; D000311:Adrenal Glands / Q000473:pathology; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D009447:Neuroblastoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D011247:Pregnancy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary; D055815:Young Adult; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule