title: [A convenient synthesis of furans using bromacetyl-pyran-2-one].
abstract: Conversions of 3-bromacetyl-4-hydroxy-6-methyl-2H-pyran-2-ones (3beta-brom-dehydroacetic acids) with amines are highly influenced by the type of amine. In contrast to aniline, where a dehydroacetic acid derivative was obtained, utilization of phenylethylamine in acetone gave a rearrangement-reaction to a basically substituted furan-2-one. In natural products furan-2-ones as butenolides are of particular importance.
authors.affiliation: Institut für Pharmazie - Pharmazeutische Chemie, Fakultät für Biowissenschaften, Pharmazie und Psychologie, Universität Leipzig, Brüderstr 34, 04103 Leipzig, Germany. briel@rz.uni-leipzig.de
authors.forename: D
authors.initials: D
authors.lastname: Briel
authors.forename: G B
authors.initials: GB
authors.lastname: Askar
authors.forename: J
authors.initials: J
authors.lastname: Ortwein
authors.forename: K
authors.initials: K
authors.lastname: Unverferth
mesh_terms: D005663:Furans / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D011753:Pyrones / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
chemical_list: D005663:Furans; D007202:Indicators and Reagents; D011753:Pyrones