A patient with medullary thyroid carcinoma and right ventricular cardiac metastasis treated by (90)Y-Dotatoc.
Medullary thyroid carcinoma (MTC) is rare derived from C cells of the thyroid gland and represents approximately 5% of all thyroid carcinomas. We report a case of a 74 years old male with MTC, diagnosed in 2002 and treated with total thyroidectomy and lymphadenectomy. A metastatic lesion was diagnosed on the right ventricle by indium-111-octreoscan, fluorine-18-fluorodeoxyglucose-positron emission tomography/computerized tomography, echocardiography, magnetic resonance imaging, high resolution computed tomography and was confirmed by histopathology. We present the results of treatment of this patient with yttrium-90-DOTA-tyr(3)-octreotide.
Bertagna
Francesco
F
Department of Nuclear Medicine, Public Hospital of Brescia, Brescia, Italy. francesco.bertagna@spedalicivili.brescia.it
Giubbini
Raffaele
R
Savelli
Giordano
G
Pizzocaro
Claudio
C
Rodella
Carlo
C
Biasiotto
Giorgio
G
Lucchini
Silvia
S
Maroldi
Roberto
R
Rosenbaum
Joshua
J
Alavi
Abass
A
D000368:Aged; D018276:Carcinoma, Medullary / Q000532:radiotherapy* / Q000556:secondary*; D006338:Heart Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D015282:Octreotide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000532:radiotherapy*; D016896:Treatment Outcome
D019275:Radiopharmaceuticals; C496730:90Y-octreotide, DOTA-Tyr(3)-; D015282:Octreotide