title: Disseminated protothecosis following traumatic Hickman line removal in a patient with leukaemia.
abstract: Human protothecosis is a rare infection caused by a member of the genus Prototheca, an ubiquitous alga. Traumatic inoculation can cause infections in the immunocompetent host while disseminated infection is mainly seen in patients with compromised immunity. We report here an unusual case of disseminated infection in a cancer patient. Traumatic removal of a Hickman catheter in this patient, led to the development of a severe skin and subcutaneous tissue infection with algaemia. These infections are often indolent and difficult to treat, with paucity of information available as to guidelines for diagnosis and effective therapeutic options.
authors.affiliation: Microbiology, Royal Gwent Hospital, Newport, Wales NP202UB, UK. gaursoma@yahoo.co.uk
authors.forename: Soma
authors.initials: S
authors.lastname: Gaur
authors.forename: Ceri
authors.initials: C
authors.lastname: Marrin
authors.forename: Rosemary A
authors.initials: RA
authors.lastname: Barnes
mesh_terms: D002408:Catheters, Indwelling / Q000009:adverse effects*; D004868:Equipment Failure; D005260:Female; D006801:Humans; D007239:Infections / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008875:Middle Aged; D009336:Necrosis / Q000473:pathology; D011525:Prototheca / Q000302:isolation & purification* / Q000472:pathogenicity; D012867:Skin / Q000473:pathology; D013909:Thorax / Q000473:pathology