title: Thyroid function: the complexity of maternal hypothyroidism during pregnancy.
abstract: Uncertainty exists about the best approach to manage levothyroxine dosage in women with hypothyroidism, once they become pregnant. The etiology of an individual's hypothyroidism might be a key determinant of the optimal time and duration of dose adjustments, say the authors of a retrospective review published in the journal Thyroid.
authors.forename: Erik K
authors.initials: EK
authors.lastname: Alexander
mesh_terms: D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine
references.citation: N Engl J Med. 1990 Jul 12;323(2):91-6
references.pmid: 2359428
references.citation: N Engl J Med. 2004 Jul 15;351(3):241-9
references.pmid: 15254282
references.citation: J Clin Endocrinol Metab. 1994 Jul;79(1):197-204
references.pmid: 8027226
references.citation: N Engl J Med. 1999 Aug 19;341(8):549-55
references.pmid: 10451459
references.citation: Eur J Endocrinol. 2004 Dec;151(6):695-700
references.pmid: 15588235
references.citation: Clin Endocrinol (Oxf). 2009 May;70(5):798-802
references.pmid: 18771569
references.citation: Thyroid. 2009 Mar;19(3):269-75
references.pmid: 19265498
references.citation: Arch Intern Med. 2000 Feb 28;160(4):526-34
references.pmid: 10695693