title: The relationship between preoperative alignment stability and postoperative motor outcomes in children with esotropia.
abstract: OBJECTIVE
  To examine the effect of preoperative alignment stability on postoperative motor outcomes in children who underwent surgery for esotropia.
  
  
  METHODS
  One hundred sixty-seven subjects (68 with infantile esotropia and 99 with acquired esotropia) aged less than 6 years had surgery after completing 18 weeks of follow-up as part of an observational study. Preoperative alignment was classified as stable, uncertain, or unstable, based on measurements taken at baseline and every 6 weeks for 18 weeks. Distance alignment measured by prism and alternate cover test was compared among stability classification groups at 6 weeks and 6 months after surgery.
  
  
  RESULTS
  Among subjects with infantile esotropia, median 6-week postoperative deviation was 2(Delta), 6(Delta), and 2(Delta) for subjects with stable, uncertain, and unstable preoperative alignment, respectively (p = 0.73 for stable vs unstable). Median 6-month postoperative deviation was 1(Delta), 9(Delta), and 1(Delta) for stable, uncertain, and unstable, respectively (p = 1.00 for stable vs unstable). Among subjects with acquired esotropia, median 6-week postoperative deviation was 6(Delta), 4(Delta), and 4(Delta) for subjects with stable, uncertain, and unstable preoperative alignment, respectively (p = 0.69 for stable vs unstable). Median 6-month postoperative deviation was 8(Delta), 4(Delta), and 6(Delta) for stable, uncertain, and unstable, respectively (p = 0.22 for stable vs unstable).
  
  
  CONCLUSIONS
  Postoperative alignment at 6 weeks and 6 months appears similar in children with stable versus unstable preoperative esotropia. Nevertheless, our finding should be interpreted with caution due to small sample size.
authors.affiliation: Jaeb Center for Health Research, Tampa, Florida 33647, USA. pedig@jaeb.org
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Christiansen
authors.forename: Danielle L
authors.initials: DL
authors.lastname: Chandler
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Holmes
authors.forename: Darron A
authors.initials: DA
authors.lastname: Bacal
authors.forename: Eileen
authors.initials: E
authors.lastname: Birch
authors.forename: Sean P
authors.initials: SP
authors.lastname: Donahue
authors.forename: Brian G
authors.initials: BG
authors.lastname: Mohney
authors.forename: Michael X
authors.initials: MX
authors.lastname: Repka
authors.forename: Lisa C
authors.initials: LC
authors.lastname: Verderber
mesh_terms: D002648:Child; D002675:Child, Preschool; D004948:Esotropia / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009801:Oculomotor Muscles / Q000503:physiopathology*; D013508:Ophthalmologic Surgical Procedures; D011184:Postoperative Period; D015348:Vision, Binocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology
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