title: [A case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response].
abstract: We report a case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response. The patient was a 72-year-old female with multiple liver metastases of cecal cancer. She underwent a right hemicolectomy and right salpingo-oophorectomy in a non-curative resection. Final findings revealed cecal cancer, type 3, 60 x 55 mm, pSI (right ovary), pN3, sH3, sP0, cM0, fStage IV, respectively. After surgery, chemotherapy with mFOLFOX6 was performed. After 4 courses, a significant tumor reduction (PR) was obtained. She died 1 year 2 months after surgery. This case suggests that chemotherapy with mFOLFOX6 is a potential regimen for AFP producing colon cancer.
authors.affiliation: Dept. of Surgery, Tottori Municipal Hospital.
authors.forename: Ken
authors.initials: K
authors.lastname: Seshimo
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Masahiro
authors.initials: M
authors.lastname: Oishi
authors.forename: Naosuke
authors.initials: N
authors.lastname: Yokomichi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ikeda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Masao
authors.initials: M
authors.lastname: Yamamura
authors.forename: Masahito
authors.initials: M
authors.lastname: Kodera
authors.forename: Reijiro
authors.initials: R
authors.lastname: Maejima
authors.forename: Keita
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Keiko
authors.initials: K
authors.lastname: Takita
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002430:Cecal Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000509:alpha-Fetoproteins; D002955:Leucovorin; D005472:Fluorouracil