Circadian biology: a neuropeptide is bound to activate its receptor.
How do circadian pacemaker neurons provide timekeeping signals by which daily rhythms are organized? Recent technological innovations in the fruitfly model system have allowed observations which suggest some important synchronizing signals may themselves not be gated.
Taghert
Paul H
PH
Department of Anatomy and Neurobiology, Washington University Medical School, Saint Louis, MO 63110, USA. taghertp@pcg.wustl.edu
D000818:Animals; D001921:Brain / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D029721:Drosophila Proteins / Q000235:genetics / Q000502:physiology*; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology*; D017952:Ganglia, Invertebrate / Q000502:physiology; D055767:Immobilized Proteins; D008124:Locomotion; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology; D009479:Neuropeptides / Q000235:genetics / Q000502:physiology*; D056950:Period Circadian Proteins / Q000502:physiology; D043562:Receptors, G-Protein-Coupled / Q000502:physiology*
D029721:Drosophila Proteins; D055767:Immobilized Proteins; D009479:Neuropeptides; C507073:PDFR protein, Drosophila; C539040:PER protein, Drosophila; D056950:Period Circadian Proteins; D043562:Receptors, G-Protein-Coupled; C113883:pdf protein, Drosophila