On-chip technologies for multidimensional separations.
We review microfluidic devices designed for multidimensional sample analysis, with a primer on relevant theory, an emphasis on protein analysis, and an eye towards future improvements and challenges to the field. Image shows results of an on-chip IEF-CE separation of a protein mixture; unpublished surface plot data from A. E. Herr.
Tia
Samuel
S
Department of Bioengineering, University of California, Berkeley, 308B Stanley Hall, MC # 1762 Berkeley, CA 94720-1762, USA.
Herr
Amy E
AE
D002851:Chromatography, High Pressure Liquid; D010316:Particle Size; D011506:Proteins / Q000302:isolation & purification*
D011506:Proteins