Prenatal maternal emotional complaints are associated with cortisol responses in toddler and preschool aged girls.
Associations between prenatal maternal emotional complaints and child behavioral and cognitive problems have been reported, with different relations for boys and girls. Fetal programming hypotheses underline these associations and state that the early development of the HPA-axis of the children may have been affected. In the present study, differences in cortisol responses of prenatally exposed and nonexposed children are examined for both sexes separately. Cortisol response patterns of a group preschool aged children that were prenatally exposed to high levels of maternal emotional complaints (N = 51) were compared to a nonexposed group (N = 52). Child saliva was collected at the start of a home visit (T1), 22 min after a mother-child interaction episode (T2), and 22 min after a potentially frustrating task (T3). Repeated measures analyses showed that prenatally exposed girls showed higher cortisol levels across the three episodes compared to nonexposed girls. No differences were found in boys. Maternal prenatal emotional complaints might be related to child HPA-axis functioning differently for boys and girls.
de Bruijn
Anouk T C E
AT
Department of Developmental, Clinical and Cross-Cultural Psychology, Tilburg University, 5000 LE Tilburg, the Netherlands. t.c.e.debruijn@uvt.nl
van Bakel
Hedwig J A
HJ
Wijnen
Hennie
H
Pop
Victor J M
VJ
van Baar
Anneloes L
AL
D000367:Age Factors; D000704:Analysis of Variance; D001007:Anxiety / Q000378:metabolism; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D003863:Depression / Q000378:metabolism; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism; D008297:Male; D008425:Maternal Behavior / Q000523:psychology; D009034:Mother-Child Relations; D010913:Pituitary-Adrenal System / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000378:metabolism*; D011446:Prospective Studies; D012463:Saliva / Q000737:chemistry; D013315:Stress, Psychological / Q000378:metabolism*; D011795:Surveys and Questionnaires
D006854:Hydrocortisone