title: Alkaloids from Sternbergia colchiciflora.
abstract: Twenty-one alkaloids and related compounds were found in Sternbergia colchiciflora (Amaryllidaceae), a hitherto not studied plant species. Twenty of them were detected by GC-MS in the crude extracts of this plant species. Ten alkaloids were isolated and their structures confirmed by NMR, MS and CD measurements. Many of the compounds found in this species, such as lycorine, tazettine, haemanthidine, are known to possess strong bioactivity. Variations in the alkaloid pattern were found during the phenological cycle of the plant. Lycorine-type compounds were dominant in the plant organs during both the flowering period and dormancy. The alkaloid pattern during both periods of leaf development and fructification was dominated by haemanthamine-type in the leaves and lycorine-type compounds in the bulbs, respectively.
authors.affiliation: Departament de Productes Naturals, Biologia Vegetal i Edafologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Catalonia, Spain.
authors.forename: Strahil
authors.initials: S
authors.lastname: Berkov
authors.forename: Jaume
authors.initials: J
authors.lastname: Bastida
authors.forename: Reneta
authors.initials: R
authors.lastname: Tsvetkova
authors.forename: Francesc
authors.initials: F
authors.lastname: Viladomat
authors.forename: Carles
authors.initials: C
authors.lastname: Codina
mesh_terms: D047151:Amaryllidaceae Alkaloids / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D019668:Liliaceae / Q000737:chemistry*; D010617:Phenanthridines / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry
chemical_list: D047151:Amaryllidaceae Alkaloids; D010617:Phenanthridines; D010936:Plant Extracts; C462104:hemanthamine; C015330:lycorine