title: Coexistence of two types of allergic hypersensitivity to drugs.
abstract: Hypersensitivity to drugs is a complex diagnostic challenge. Detailed medical history remains the mainstay of drug hypersensitivity evaluation, which further determines diagnostic procedures, especially the types of skin tests to be performed. The current paper presents the case of a female patient with coexisting features of supposed immunoglobulin E (IgE) dependent allergic hypersensitivity to fluoroquinolones and those of non-IgE dependent allergic hypersensitivity to povidone-iodine. Hypersensitivity was diagnosed based on the appropriately selected skin tests.
authors.affiliation: Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Zabrze, Poland. joagluck@mp.pl
authors.forename: Joanna
authors.initials: J
authors.lastname: Glück
authors.forename: Barbara
authors.initials: B
authors.lastname: Rymarczyk
authors.forename: Barbara
authors.initials: B
authors.lastname: Rogala
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D003876:Dermatitis, Atopic / Q000209:etiology* / Q000276:immunology; D003875:Drug Eruptions / Q000209:etiology* / Q000276:immunology; D005148:Facial Dermatoses / Q000139:chemically induced; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D011206:Povidone-Iodine / Q000009:adverse effects*; D012882:Skin Tests / Q000379:methods
chemical_list: D000891:Anti-Infective Agents, Local; D024841:Fluoroquinolones; D007073:Immunoglobulin E; D011206:Povidone-Iodine