title: Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels-Alder reactions: access to bridged- and fused-ring heterocycles.
abstract: The Pd-catalysed intramolecular alpha-arylation of alpha-amino acid esters provides a useful methodology for the synthesis of substituted isoindole derivatives, which have been used in Diels-Alder reactions to access diverse skeletal frameworks.
authors.affiliation: Laboratori de Química Orgànica, Facultat de Farmàcia, and Institut de Biomedicina, Universitat de Barcelona, Av., Joan XXIII s/n, 08028, Barcelona, Spain. dsole@ub.edu
authors.forename: Daniel
authors.initials: D
authors.lastname: Solé
authors.forename: Olga
authors.initials: O
authors.lastname: Serrano
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D006572:Heterocyclic Compounds, Bridged-Ring / Q000138:chemical synthesis; D054833:Isoindoles / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry
chemical_list: D000596:Amino Acids; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004952:Esters; D006571:Heterocyclic Compounds; D006572:Heterocyclic Compounds, Bridged-Ring; D054833:Isoindoles; D010165:Palladium