title: Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C.
abstract: OBJECTIVE
  To report 2 cases of delayed-onset, bleb-related endophthalmitis induced by Gemella species.
  
  
  METHODS
  Interventional case report.
  
  
  RESULTS
  Two patients developed bleb-related ocular infection attributable to Gemella haemolysans and Gemella morbillorum after trabeculectomy with adjunctive mitomycin C. Both patients had thin-walled cystic filtering blebs before ocular infection. One patient underwent urgent vitrectomy with intravitreal injection of ceftazidime and vancomycin. The other received an intraocular injection of vancomycin and ceftazidime. After surgical intervention, 2 cases were administered topical levofloxacin and sulfobenzylpenicillin, and intravenous cefpirome. The DNA from the microorganism was sequenced and identified as G. haemolysans and G. morbillorum.
  
  
  CONCLUSIONS
  Gemella species should be added to the long list of organisms that may rarely cause bleb-associated endophthalmitis.
authors.affiliation: Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu-shi 501-1194, Japan. sawadaa-gif@umin.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Sawada
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Katada
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kawakami
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Hiroshige
authors.initials: H
authors.lastname: Mikamo
authors.forename: Kunitomo
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001768:Blister / Q000382:microbiology; D003228:Conjunctiva / Q000601:surgery; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011183:Postoperative Complications; D040141:Staphylococcaceae / Q000302:isolation & purification*; D019738:Surgically-Created Structures / Q000382:microbiology; D014130:Trabeculectomy; D014821:Vitrectomy
chemical_list: D000900:Anti-Bacterial Agents; D016685:Mitomycin