Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy.
BACKGROUND
A rare complication of mature cystic teratoma of the ovary is malignant transformation, mostly being squamous cell carcinoma (SCC). Due to small case series, there are no established standard surgical and postoperative procedures.


METHODS
A 41-year-old pregnant woman presented with a right ovarian tumour. At 14 weeks of gestation, laparotomy with oophorectomy was performed. Histology revealed a pT1a poorly differentiated SCC with lymphovascular invasion. She delivered a healthy infant at 39 weeks of gestation. Nine weeks after delivery, she underwent complete surgical resection and was staged pT1a, pN0 (0/40) pMx, G0. No further treatment was given and 37 months later she is still free of disease.


CONCLUSIONS
For this rare entity complete surgical resection seems to be a safe treatment.
Budiman
Helen Diana
HD
Department of Obstetrics and Gynaecology, Grosshadern, Ludwig-Maximilians-University of Munich 81377, Munich, Germany. Helen.Budiman@med.uni-muenchen.de
Burges
Alexander
A
Rühl
Ina M
IM
Friese
Klaus
K
Hasbargen
Uwe
U
D000328:Adult; D002471:Cell Transformation, Neoplastic; D003884:Dermoid Cyst / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D018307:Neoplasms, Squamous Cell / Q000473:pathology* / Q000601:surgery; D010048:Ovarian Cysts / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D011261:Pregnancy Trimester, First