title: Thyroid function: Thyroid hormones, iodine and the brain-an important concern.
abstract: Exposure of the fetus to low levels of thyroid hormones for extended periods during pregnancy can lead to irreversible brain damage and potential delays in neurological and behavioral development. What are the exact mechanisms behind this abnormality, and can prompt initiation of maternal iodine supplementation prevent this adverse effect?
authors.forename: Peter
authors.initials: P
authors.lastname: Laurberg
mesh_terms: D001921:Brain / Q000196:embryology / Q000254:growth & development / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D007455:Iodine / Q000378:metabolism* / Q000652:urine; D008297:Male; D011247:Pregnancy; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D007455:Iodine; D013974:Thyroxine
references.citation: Public Health Nutr. 2007 Dec;10(12A):1547-52; discussion 1553
references.pmid: 18053278
references.citation: Thyroid. 2009 May;19(5):511-9
references.pmid: 19348584
references.citation: Public Health Nutr. 2007 Dec;10(12A):1554-70
references.pmid: 18053280
references.citation: Clin Endocrinol (Oxf). 1999 Feb;50(2):149-55
references.pmid: 10396355
references.citation: Obstet Gynecol. 2005 Feb;105(2):239-45
references.pmid: 15684146
references.citation: Am J Obstet Gynecol. 2009 Mar;200(3):260.e1-6
references.pmid: 19114271
references.citation: Am J Clin Nutr. 2006 Jan;83(1):108-14
references.pmid: 16400058
references.citation: Public Health Nutr. 2007 Dec;10(12A):1606-11
references.pmid: 18053287
references.citation: N Engl J Med. 1999 Aug 19;341(8):549-55
references.pmid: 10451459
references.citation: J Clin Endocrinol Metab. 2004 Dec;89(12):6054-60
references.pmid: 15579758