title: Taste perception: how sweet it is (to be transcribed by you).
abstract: In mammals, sweet taste is mediated largely by a single receptor. New work shows that polymorphisms in the promoter region of one subunit contribute to variation in sweet perception in the human population.
authors.affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: Joel D
authors.initials: JD
authors.lastname: Mainland
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Matsunami
mesh_terms: D006801:Humans; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D055697:Taste Perception / Q000235:genetics* / Q000502:physiology
chemical_list: D043562:Receptors, G-Protein-Coupled; C431926:taste receptors, type 1
references.citation: Curr Biol. 2005 Feb 22;15(4):322-7
references.pmid: 15723792
references.citation: Curr Biol. 2006 Sep 19;16(18):R792-4
references.pmid: 16979544
references.citation: Ann N Y Acad Sci. 1974 Sep 27;237(0):279-85
references.pmid: 4529064
references.citation: Nat Neurosci. 2001 May;4(5):492-8
references.pmid: 11319557
references.citation: PLoS Genet. 2005 Jul;1(1):27-35
references.pmid: 16103917
references.citation: Science. 2003 Aug 8;301(5634):850-3
references.pmid: 12869700
references.citation: Chem Senses. 2001 Sep;26(7):925-33
references.pmid: 11555487
references.citation: Science. 2003 Feb 21;299(5610):1221-5
references.pmid: 12595690
references.citation: Biochem Biophys Res Commun. 2001 Apr 27;283(1):236-42
references.pmid: 11322794
references.citation: Nat Genet. 2001 May;28(1):58-63
references.pmid: 11326277
references.citation: Cell. 2003 Oct 31;115(3):255-66
references.pmid: 14636554
references.citation: Cell. 2001 Aug 10;106(3):381-90
references.pmid: 11509186
references.citation: Curr Biol. 2009 Aug 11;19(15):1288-93
references.pmid: 19559618
references.citation: Chem Senses. 2006 Sep;31(7):599-611
references.pmid: 16801379