Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours.
Granchi
Carlotta
C
Dipartimento di Scienze Farmaceutiche, Università di Pisa, Via Bonanno 6, I-56126 Pisa (Italy).
Funaioli
Tiziana
T
Erler
Janine T
JT
Giaccia
Amato J
AJ
Macchia
Marco
M
Minutolo
Filippo
F
D000629:Aminopropionitrile / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D015687:Cell Hypoxia / Q000187:drug effects; D045744:Cell Line, Tumor; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D000860:Hypoxia / Q000201:enzymology*; D009369:Neoplasms / Q000201:enzymology*; D010084:Oxidation-Reduction; D011355:Prodrugs / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D008249:Protein-Lysine 6-Oxidase / Q000037:antagonists & inhibitors*
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D011355:Prodrugs; D000629:Aminopropionitrile; D008249:Protein-Lysine 6-Oxidase
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