title: Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica.
abstract: Ultra-small superparamagnetic iron oxide nanoparticles (SPIOs) were synthesized by co-precipitation of iron chloride salts with ammonia and then encapsulated with thin (~2nm) layers of silica. The particles have been characterized for size, diffraction pattern, surface charge, and magnetic properties. This rapid and economical synthesis has a number of industrial applications; however, the silica-coated particles have been optimized for use in medical applications as MR contrast agents, biosensors, DNA capturing, bioseparation and enzyme immobilization.
authors.affiliation: Oxford University Begbroke Science Park, Sandy Lane, Kidlington, Oxon OX5 1PF, UK. Email: Ambika.Bumb@eng.ox.ac.uk , Peter.Dobson@begbroke.ox.ac.uk.
authors.forename: A
authors.initials: A
authors.lastname: Bumb
authors.forename: M W
authors.initials: MW
authors.lastname: Brechbiel
authors.forename: P L
authors.initials: PL
authors.lastname: Choyke
authors.forename: L
authors.initials: L
authors.lastname: Fugger
authors.forename: A
authors.initials: A
authors.lastname: Eggeman
authors.forename: D
authors.initials: D
authors.lastname: Prabhakaran
authors.forename: J
authors.initials: J
authors.lastname: Hutchinson
authors.forename: P J
authors.initials: PJ
authors.lastname: Dobson
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