title: Primary cutaneous anaplastic large cell lymphoma of the vulva: a typical cutaneous lesion with an 'atypical' presenting site.
abstract: Non-Hodgkin lymphoma of vulva is exceedingly rare and it often poses a diagnostic challenge if their existence is not suspected. We report a patient who has primary cutaneous anaplastic large cell (C-ALCL) with an unusual presentation as a vulvar ulcer. She received a brief course of chemotherapy followed by local irradiation and has remained disease-free more than a year from the time of diagnosis. To our knowledge, primary C-ALCL involving the vulva has never been reported. Despite its typical cutaneous manifestation of C-ALCL, the uncommon presenting site of this entity warrants recognition because of its prognostic and therapeutic implication.
authors.affiliation: Department of Hematology-Oncology, National University Hospital, Singapore, 119074, Singapore. liangpiu@yahoo.com.sg.
authors.forename: Liang Piu
authors.initials: LP
authors.lastname: Koh
authors.affiliation: Department of Radiation Oncology, National University Hospital, Singapore, Singapore.
authors.forename: Lea Choung
authors.initials: LC
authors.lastname: Wong
authors.affiliation: Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
authors.forename: Siok Bian
authors.initials: SB
authors.lastname: Ng
authors.affiliation: Department of Hematology-Oncology, National University Hospital, Singapore, 119074, Singapore.
authors.forename: Michelle L M
authors.initials: MLM
authors.lastname: Poon
authors.affiliation: Department of Obstetrics and Gynaecology, National University Hospital, Singapore, Singapore.
authors.forename: Jeffrey J H
authors.initials: JJH
authors.lastname: Low
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D049268:Positron-Emission Tomography; D011379:Prognosis; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D014846:Vulvar Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy
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