title: Nickel(0)-catalyzed [2 + 2 + 2] cycloaddition of diynes and 3,4-pyridynes: novel synthesis of isoquinoline derivatives.
abstract: A transition metal-catalyzed [2 + 2 + 2] cycloaddition between alpha,omega-diynes and 3,4-pyridynes has been realized for the first time, producing isoquinolines in good yields by using a nickel(0) catalyst.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Iwayama
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sato
mesh_terms: D002384:Catalysis; D053280:Diynes / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D009532:Nickel / Q000737:chemistry*
chemical_list: D053280:Diynes; D007546:Isoquinolines; D009532:Nickel