Taste perception: how sweet it is (to be transcribed by you).
In mammals, sweet taste is mediated largely by a single receptor. New work shows that polymorphisms in the promoter region of one subunit contribute to variation in sweet perception in the human population.
Mainland
Joel D
JD
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Matsunami
Hiroaki
H
D006801:Humans; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D055697:Taste Perception / Q000235:genetics* / Q000502:physiology
D043562:Receptors, G-Protein-Coupled; C431926:taste receptors, type 1
Curr Biol. 2005 Feb 22;15(4):322-7
15723792
Curr Biol. 2006 Sep 19;16(18):R792-4
16979544
Ann N Y Acad Sci. 1974 Sep 27;237(0):279-85
4529064
Nat Neurosci. 2001 May;4(5):492-8
11319557
PLoS Genet. 2005 Jul;1(1):27-35
16103917
Science. 2003 Aug 8;301(5634):850-3
12869700
Chem Senses. 2001 Sep;26(7):925-33
11555487
Science. 2003 Feb 21;299(5610):1221-5
12595690
Biochem Biophys Res Commun. 2001 Apr 27;283(1):236-42
11322794
Nat Genet. 2001 May;28(1):58-63
11326277
Cell. 2003 Oct 31;115(3):255-66
14636554
Cell. 2001 Aug 10;106(3):381-90
11509186
Curr Biol. 2009 Aug 11;19(15):1288-93
19559618
Chem Senses. 2006 Sep;31(7):599-611
16801379