title: Behavioural inhibition: A predictor of anxiety.
abstract: Anxiety disorders are prevalent and contribute to emotional suffering and significant economic loss. Early identification and treatment are essential, not only to reduce the associated morbidity, disability and mortality of the anxiety disorders themselves, but also to minimize development of frequent comorbidities such as depression and substance abuse. To understand the factors that increase susceptibility to developing anxiety disorders, a temperamental construct called behavioural inhibition, which refers to the consistent tendency of some children to demonstrate fear and withdrawal in novel situations, has been developed. The present article reviews studies investigating this model as a premorbid predictor of those at risk for developing anxiety disorders, including prospective studies of children at risk as well as retrospective and family studies. In summary, these data suggest the usefulness of this model and a need for further research to determine the optimal management of behaviourally inhibited children as a potential way to prevent adult psychopathology.
authors.affiliation: Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario.
authors.forename: Martin
authors.initials: M
authors.lastname: Svihra
authors.forename: Martin A
authors.initials: MA
authors.lastname: Katzman
references.citation: J Clin Psychiatry. 2001;62 Suppl 17:55-9
references.pmid: 11495098
references.citation: J Am Acad Child Adolesc Psychiatry. 1999 Aug;38(8):1008-15
references.pmid: 10434493
references.citation: Child Dev. 1996 Apr;67(2):508-22
references.pmid: 8625725
references.citation: J Nerv Ment Dis. 1998 Jul;186(7):425-31
references.pmid: 9680044
references.citation: Arch Gen Psychiatry. 1988 May;45(5):463-70
references.pmid: 3358645
references.citation: Arch Gen Psychiatry. 1990 Jan;47(1):21-6
references.pmid: 2294852
references.citation: J Clin Psychiatry. 1991 Nov;52 Suppl:5-9
references.pmid: 1757458
references.citation: Am J Psychiatry. 1992 Apr;149(4):475-81
references.pmid: 1554032
references.citation: J Anxiety Disord. 1998 Jan-Feb;12(1):1-20
references.pmid: 9549606
references.citation: J Am Acad Child Adolesc Psychiatry. 1992 Jan;31(1):103-11
references.pmid: 1537760
references.citation: J Clin Psychiatry. 1999 Jul;60(7):427-35
references.pmid: 10453795
references.citation: Am J Psychiatry. 2000 Dec;157(12):2002-10
references.pmid: 11097967
references.citation: Am J Psychiatry. 1984 Jan;141(1):1-9
references.pmid: 6691419
references.citation: J Psychiatr Res. 1991;25(1-2):49-65
references.pmid: 2027095
references.citation: J Am Acad Child Adolesc Psychiatry. 1998 Dec;37(12):1308-16
references.pmid: 9847504
references.citation: J Am Acad Child Adolesc Psychiatry. 1997 Jul;36(7):910-7
references.pmid: 9204668
references.citation: Child Dev. 1987 Dec;58(6):1459-73
references.pmid: 3691195
references.citation: Am J Psychiatry. 2001 Oct;158(10):1673-9
references.pmid: 11579001
references.citation: Am J Psychiatry. 1993 Apr;150(4):600-7
references.pmid: 8465877