title: Combination of autologous fascia lata and fat injection into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis.
abstract: OBJECTIVE
  To apply the technique of injection of a combination of autologous fascia lata and fat into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis and to evaluate the therapeutic effect in 12 patients who underwent the procedure.
  
  
  METHODS
  Retrospective analysis of 12 patients.
  
  
  METHODS
  Academic research.
  
  
  METHODS
  A mixture of autologous fascia lata and fat was injected into the thyroarytenoid muscle of the paralyzed vocal fold in 12 patients.
  
  
  METHODS
  Videolaryngostroboscopy was performed to observe the changes to the vocal fold. The patients' phonatory function before and after surgery was assessed by computerized acoustic analysis and by blinded perceptual evaluation.
  
  
  RESULTS
  Videolaryngostroboscopy demonstrated that the paralyzed vocal folds in these patients were pushed medially after the procedure. Statistically significant improvements were found in the perturbation measurements (jitter and shimmer), harmonics to noise ratio, and maximum phonation time. Ratings by a panel of voice experts also showed each voice to be statistically significantly improved after the procedure. No complications were noted.
  
  
  CONCLUSIONS
  A combination of autologous fascia lata and fat injected into the vocal fold for unilateral vocal fold paralysis is a safe and effective therapy.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Jinling Hospital, Clinical Medical College of Nanjing University, 305 E Zhongshan Road, Nanjing, China.
authors.forename: You
authors.initials: Y
authors.lastname: Cheng
authors.forename: Ze-qing
authors.initials: ZQ
authors.lastname: Li
authors.forename: Jin-zhong
authors.initials: JZ
authors.lastname: Huang
authors.forename: Fei
authors.initials: F
authors.lastname: Xue
authors.forename: Man-jie
authors.initials: MJ
authors.lastname: Jiang
authors.forename: Kun-min
authors.initials: KM
authors.lastname: Wu
authors.forename: Qiu-ping
authors.initials: QP
authors.lastname: Wang
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005206:Fascia Lata / Q000637:transplantation*; D005260:Female; D006801:Humans; D007267:Injections; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014741:Video Recording; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000601:surgery