Specific gene hypomethylation and cancer: new insights into coding region feature trends.
Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.
Daura-Oller
Elias
E
Biochemistry and Biotechnology Department, Faculty of Chemistry, Rovira i Virgili, University (URV), c/ Marcel.li Domingo, s/n. Campus Sescelades, 43007 Tarragona, Spain.
Cabre
Maria
M
Montero
Miguel A
MA
Paternain
Jose L
JL
Romeu
Antoni
A
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