title: Sesquiterpenoids from Pilea cavaleriei subsp. crenata.
abstract: Three new humulane-type sesquiterpenes, 8-O-(p-coumaroyl)-5beta-hydroperoxy-1(10)E,4(15)-humuladien-8alpha-ol (1), 8-O-(3-nitro-p-coumaroyl)-1(10)E,4(15)-humuladien-5beta,8alpha-diol (2) and 8-O-(p-coumaroyl)-1(10)E,4(5)E-humuladien-8-ol (3), and a new copaborneol derivative, 1-O-p-coumaroyl-copaborneol (4), have been isolated from the methanol extract of Pileacavaleriei Lévl. subsp. crenata C. J. Chen. Their structures were elucidated using spectroscopic methods. Cytotoxic and antimicrobial activities of the isolated compounds were evaluated.
authors.affiliation: Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
authors.forename: Gui-Hua
authors.initials: GH
authors.lastname: Tang
authors.forename: Chang-Song
authors.initials: CS
authors.lastname: Sun
authors.forename: Chun-Lin
authors.initials: CL
authors.lastname: Long
authors.forename: Ma-Lin
authors.initials: ML
authors.lastname: Li
authors.forename: Yue-Hu
authors.initials: YH
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Luo
authors.forename: Hong-Sheng
authors.initials: HS
authors.lastname: Wang
authors.forename: Ya-Na
authors.initials: YN
authors.lastname: Shi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D027003:Urticaceae / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D012717:Sesquiterpenes