title: [Maxillary and mandibular carcinogenesis: research and prospects].
abstract: Development and growth of odontogenic tumours depend on impairment of numerous genes and molecules. In recent years, most of the genes involved in dental development were identified. This produced a new basis for the study of oral pathology and maxillofacial carcinogenesis. A better understanding of these molecular phenomena should allow to better determine the evolution of such lesions. Research breakthroughs should facilitate the development of new molecular and genetic therapeutic perspectives.
authors.affiliation: Service de chirurgie maxillofaciale et stomatologie, hôpital adulte de Pitié-Salpêtrière, université Pierre-et-Marie-Curie-Paris 6, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. blandine.ruhin@psl.aphp.fr
authors.forename: B
authors.initials: B
authors.lastname: Ruhin
authors.forename: V
authors.initials: V
authors.lastname: Descroix
authors.forename: A
authors.initials: A
authors.lastname: Picard
authors.forename: A
authors.initials: A
authors.lastname: Berdal
mesh_terms: D003746:Dental Enamel Proteins / Q000235:genetics; D018865:Dental Research; D006801:Humans; D008339:Mandibular Neoplasms / Q000209:etiology* / Q000235:genetics; D008441:Maxillary Neoplasms / Q000209:etiology* / Q000235:genetics; D008967:Molecular Biology; D009805:Odontogenesis / Q000235:genetics; D009808:Odontogenic Tumors / Q000209:etiology / Q000235:genetics; D010014:Osteolysis / Q000235:genetics
chemical_list: D003746:Dental Enamel Proteins