title: Desorption electrospray ionization mass spectrometry for monitoring the kinetics of Baeyer-Villiger solid-state organic reactions.
abstract: Desorption electrospray ionization mass spectrometry (DESI-MS) has been used for monitoring solid-state organic reaction in ambient air, specifically the Baeyer-Villiger (BV) type reaction involving the oxidation of ketones (benzophenone or deoxybenzoin) by m-chloroperbenzoic acid (m-CPBA) in solid-state. The DESI mass spectra obtained at regular intervals during the BV reaction processes are featured, with the amount of ester products increasing as those of ketone reactants decrease. Quantitative analyses of relative intensities of the product, made to quantify the reaction degree of typical solid-state organic reaction (SSOR), show a precision with RSDs of around 5% to 12%, though the RSDs for direct analysis of intensities of the reactant or the product in the solid-state are obviously larger. The kinetics of the Baeyer-Villiger type reactions in solid-state are shown to be dramatically different, in reaction rate, kinetic curve, as well as concentration dependence, from those of the same reactions taking place in solution.
authors.affiliation: State Key Laboratory for Physical Chemistry of Solid Surfaces, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Xie
authors.forename: Li-Fang
authors.initials: LF
authors.lastname: He
authors.forename: Shui-Chao
authors.initials: SC
authors.lastname: Lin
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Su
authors.forename: Su-Yuan
authors.initials: SY
authors.lastname: Xie
authors.forename: Rong-Bin
authors.initials: RB
authors.lastname: Huang
authors.forename: Lan-Sun
authors.initials: LS
authors.lastname: Zheng
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