A novel fungal pathogen under the spotlight--Acremonium spp. associated fungaemia in an immunocompetent host.
Acremonium spp. are filamentous, cosmopolitan fungi frequently isolated from plant debris and soil, they are known to result in invasive infections in the setting of severe immunosuppression. In this letter, we present a case of catheter-related fungaemia associated with Acremonium spp. in a patient with chronic renal failure. After removal of the subclavian catheter, the patient was treated successfully with voriconazole, with a loading dose of 400 mg followed by a maintenance dose of 200 mg bid. To the best of our knowledge, this is the first paper reporting Acremonium spp. associated fungaemia in a relatively immunocompetent host. We also discuss the diagnosis and treatment of Acremonium spp. associated infections in the context of current literature.
Purnak
Tugrul
T
Beyazit
Yavuz
Y
Sahin
Gulsen Ozkaya
GO
Shorbagi
Ali
A
Akova
Murat
M
D000164:Acremonium / Q000302:isolation & purification* / Q000502:physiology; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D011743:Pyrimidines / Q000627:therapeutic use; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole