Kinetic patterns of Candida albicans germ tube antibody in critically ill patients: influence on mortality.
The influence of kinetic patterns of Candida albicans germ tube antibodies (CAGTA) on mortality was analyzed in six intensive care units. Statistically significant lower mortality rates were found in patients with patterns of increasing CAGTA titers who had been treated with antifungal agents. Thus, antifungal treatment should be considered when CAGTA titers are increasing in critically ill patients.
Zaragoza
Rafael
R
Intensive Care Unit and Department of Microbiology, Valencia, Spain. zaragozar@ono.com
Pemán
Javier
J
Quindós
Guillermo
G
Iruretagoyena
Jose R
JR
Cuétara
María S
MS
Ramírez
Paula
P
Gómez
Maria D
MD
Camarena
Juan J
JJ
Viudes
Angel
A
Pontón
José
J
D000908:Antibodies, Fungal / Q000097:blood*; D000935:Antifungal Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000276:immunology*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000401:mortality*; D016638:Critical Illness; D006801:Humans; D007700:Kinetics; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
D000908:Antibodies, Fungal; D000935:Antifungal Agents
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