Ontogenetic features of the expression of mRNA isoforms for leukemia-inhibitory factor in human fetal tissues and mononuclear cells.
The expression of leukemia-inhibitory factor mRNA in human fetal tissues and mononuclear cells was studied during ontogeny. The expression of mRNA isoforms for leukemia-inhibitory factor was tissue-specific at the stage of prenatal development. The transition from antenatal and neonatal development to the postnatal period was accompanied by a decrease in the expression of mRNA isoforms for leukemia-inhibitory factor in mononuclear cells.
Sadovskaya
V A
VA
Institute of Clinical Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Sennikov
S V
SV
Ostanin
A A
AA
Seledtsova
G V
GV
Silkov
A N
AN
Kozlov
V A
VA
D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005333:Fetus / Q000196:embryology / Q000503:physiopathology*; D015870:Gene Expression; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D007231:Infant, Newborn; D053605:Leukemia Inhibitory Factor / Q000097:blood / Q000235:genetics / Q000378:metabolism*; D007963:Leukocytes, Mononuclear / Q000502:physiology*; D011247:Pregnancy; D020033:Protein Isoforms / Q000097:blood / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism
C507837:LIF protein, human; D053605:Leukemia Inhibitory Factor; D020033:Protein Isoforms; D012333:RNA, Messenger