Effects of limonoids from Cipadessa fruticosa on fall armyworm.
Six mexicanolide limonoids isolated from the dichloromethane extract of the fruits of Cipadessa fruticosa Blume (Meliaceae) were evaluated against Spodoptera frugiperda (J. E. Smith). Gedunin was used as a positive control. When incorporated into an artificial diet of neonates at 50.0 mg kg(-1), febrifugin A showed 73.3% mortality. All the compounds showed moderate insecticidal activity, except for ruageanin A, when compared with the control. Febrifugin also showed growth inhibition and antifeedant activities (at 100.0 mg kg(-1)). The correlation between the insecticidal activity of the isolated compounds and their chemical structure was discussed.
Matos
Andreia P
AP
Departamento de Química, Universidade Federal de São Carlos, Caixa Postal 676, CEP 13565-905, São Carlos--SP, Brazil.
Leite
Ana C
AC
Batista-Pereira
Luciane G
LG
Vieira
Paulo C
PC
Fernandes
Josäo B
JB
da Silva
Maria Fátima das G F
MF
D000818:Animals; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D029582:Meliaceae / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D010880:Piperidines / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D011679:Pupa / Q000187:drug effects; D011799:Quinazolines / Q000494:pharmacology; D018411:Spodoptera / Q000187:drug effects*
D007306:Insecticides; D036701:Limonins; D010880:Piperidines; D010936:Plant Extracts; D011799:Quinazolines; C106014:gedunin; C001207:febrifugine