title: A new sesquiterpene from the fruits of Daucus carota L.
abstract: Phytochemical investigation of the fruits of Daucus carota L. resulted in the isolation of a new sesquiterpene named as daucucarotol (1). Its structure was elucidated on the basis of 1D and 2D NMR experiments, coupled with MS studies. To our knowledge, compound 1 is the first example for a natural eudesmane sesquiterpene with a hydroxymethyl group located at a methine carbon rather than a usual quaternary carbon in the two fused six-membered ring systems.
authors.affiliation: Department of Biomedical Engineering, Zhejiang University,Zhejiang Provincial Key Laboratory for Chinese Medicine Screening, Exploitation & Medicinal Effectiveness Appraisc for Cardio-cerebral, Vascular & Nervous System, The Key Laboratory of Biomedical Engineering Ministry of Education,Hangzhou, China. zxxtjk@gmail.com.
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Fu
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Tao
authors.initials: T
authors.lastname: Yi
authors.forename: Jing-Kui
authors.initials: JK
authors.lastname: Tian
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D018552:Daucus carota / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D012717:Sesquiterpenes
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