title: Male gamblers have significantly greater salivary cortisol before and after betting on a horse race, than do female gamblers.
abstract: Prevalence rates of gambling are influenced by gender. Among normative populations, hypothalamic-pituitary-adrenal (HPA) axis response to stress is affected by gender. However, pathological, compared to recreational, gamblers demonstrate perturbations in HPA activation in response to gambling stimuli. We examined whether there were gender differences in HPA response to gambling in a naturalistic setting among horse-race bettors and scratch-off lottery bettors. Salivary cortisol was collected from horse-race gamblers (n=32) and scratch-off lottery ticket players (n=39) before and after (0, 10, or 20 min) betting on a horse race at an off-track betting establishment. Salivary cortisol levels were significantly higher among men than among women, both prior to and following, betting on a horse race. Among women, but not men, there was a decline in salivary cortisol across time in scratch-off bettors, whereas women horse-race bettors maintained consistent low concentrations of salivary cortisol at every time point sampled. Together these data suggest that engaging in gambling may have different effects on stress responses of men, compared to women. Whether these gender differences in HPA activation contribute to gender-related differences in gambling behavior is the subject of ongoing investigation.
authors.affiliation: Department of Psychology, The University at Albany-SUNY, Albany, NY 12222, USA.
authors.forename: C
authors.initials: C
authors.lastname: Franco
authors.forename: J J
authors.initials: JJ
authors.lastname: Paris
authors.forename: E
authors.initials: E
authors.lastname: Wulfert
authors.forename: C A
authors.initials: CA
authors.lastname: Frye
mesh_terms: D000328:Adult; D000818:Animals; D005260:Female; D005715:Gambling; D006736:Horses; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012309:Risk-Taking; D012463:Saliva / Q000378:metabolism*; D012737:Sex Factors; D011795:Surveys and Questionnaires
chemical_list: D006854:Hydrocortisone
references.citation: Brain Res. 1993 Jul 9;616(1-2):315-9
references.pmid: 8358623
references.citation: Can J Psychiatry. 2007 Oct;52(10):657-65
references.pmid: 18020113
references.citation: Brain Res Brain Res Rev. 1997 Dec;25(3):359-72
references.pmid: 9495563
references.citation: Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15236-41
references.pmid: 17015825
references.citation: Am J Public Health. 1998 Jul;88(7):1093-6
references.pmid: 9663161
references.citation: Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11738-42
references.pmid: 8265619
references.citation: Psychoneuroendocrinology. 2003 Jan;28(1):35-47
references.pmid: 12445835
references.citation: J Clin Endocrinol Metab. 1996 May;81(5):1956-60
references.pmid: 8626864
references.citation: Psychoneuroendocrinology. 2006 Sep;31(8):976-87
references.pmid: 16879926
references.citation: Ann N Y Acad Sci. 1995 Dec 29;771:665-76
references.pmid: 8597440
references.citation: Drug Alcohol Depend. 1998 Dec 1;53(1):67-77
references.pmid: 10933341
references.citation: Int J Addict. 1989 Apr;24(4):337-50
references.pmid: 2793286
references.citation: Physiol Behav. 2007 Nov 23;92(4):583-90
references.pmid: 17572453
references.citation: Am J Phys Anthropol. 1998 Jun;106(2):249-53
references.pmid: 9637187
references.citation: Psychosom Med. 1999 Mar-Apr;61(2):154-62
references.pmid: 10204967
references.citation: Psychiatry Res. 2008 May 30;159(1-2):67-76
references.pmid: 18314202
references.citation: Psychosom Med. 1999 Mar-Apr;61(2):197-204
references.pmid: 10204973
references.citation: Ann N Y Acad Sci. 2008 Oct;1141:105-30
references.pmid: 18991954
references.citation: Psychoneuroendocrinology. 2001 Apr;26(3):225-40
references.pmid: 11166486
references.citation: J Clin Psychiatry. 2003 Mar;64(3):295-301
references.pmid: 12716271
references.citation: Br J Psychiatry. 1988 Nov;153:684-6
references.pmid: 3255458
references.citation: Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3113-23
references.pmid: 18653439
references.citation: Horm Behav. 2008 Jan;53(1):96-103
references.pmid: 17945232
references.citation: Psychosom Med. 1992 Nov-Dec;54(6):648-57
references.pmid: 1454958
references.citation: Addiction. 1999 Mar;94(3):425-30
references.pmid: 10605871
references.citation: Behav Neurosci. 2007 Oct;121(5):871-6
references.pmid: 17907819
references.citation: Psychoneuroendocrinology. 1999 Feb;24(2):227-41
references.pmid: 10101730
references.citation: Arch Gen Psychiatry. 1988 Apr;45(4):369-73
references.pmid: 2451490
references.citation: Eur J Appl Physiol Occup Physiol. 1998 May;77(6):523-6
references.pmid: 9650737
references.citation: J Gambl Stud. 1994 Sep;10(3):275-85
references.pmid: 24234924
references.citation: Biol Psychiatry. 2000 Nov 1;48(9):948-53
references.pmid: 11074233
references.citation: Psychiatr Clin North Am. 1992 Sep;15(3):647-60
references.pmid: 1409026
references.citation: J Psychosom Res. 2002 Oct;53(4):865-71
references.pmid: 12377295
references.citation: Psychopharmacology (Berl). 2006 Dec;189(2):175-86
references.pmid: 17047935
references.citation: Psychoneuroendocrinology. 2004 Nov;29(10):1272-80
references.pmid: 15288706
references.citation: J Psychosom Res. 1999 Jun;46(6):591-8
references.pmid: 10454175
references.citation: Pharmacol Biochem Behav. 2007 Apr;86(4):813-21
references.pmid: 17482248
references.citation: Addiction. 2006 Sep;101 Suppl 1:142-51
references.pmid: 16930171
references.citation: Psychol Addict Behav. 2005 Sep;19(3):311-6
references.pmid: 16187811
references.citation: J Clin Endocrinol Metab. 1998 May;83(5):1756-61
references.pmid: 9589688
references.citation: Addict Behav. 2004 Nov;29(8):1685-90
references.pmid: 15451138
references.citation: Clin J Pain. 2003 Jul-Aug;19(4):233-9
references.pmid: 12840617
references.citation: J Gambl Stud. 1994 Dec;10(4):399-409
references.pmid: 24234973
references.citation: J Gen Intern Med. 2002 Sep;17(9):721-32
references.pmid: 12220370
references.citation: Psychopharmacology (Berl). 2001 Dec;158(4):343-59
references.pmid: 11797055
references.citation: Psychol Addict Behav. 2008 Sep;22(3):380-390
references.pmid: 18778131
references.citation: Am J Psychiatry. 1987 Sep;144(9):1184-8
references.pmid: 3631315
references.citation: Brain Res. 1993 Sep 17;622(1-2):315-20
references.pmid: 8242374
references.citation: Addict Biol. 2007 Mar;12(1):30-4
references.pmid: 17407495
references.citation: Addiction. 2001 Jun;96(6):871-9
references.pmid: 11399218
references.citation: Dev Psychobiol. 2008 Dec;50(8):807-18
references.pmid: 18688807
references.citation: J Nerv Ment Dis. 2002 Jul;190(7):462-9
references.pmid: 12142848
references.citation: Physiol Behav. 2010 Feb 9;99(2):230-3
references.pmid: 19361537
references.citation: Am J Drug Alcohol Abuse. 2000 Nov;26(4):523-35
references.pmid: 11097190
references.citation: Psychoneuroendocrinology. 2002 Jan-Feb;27(1-2):13-33
references.pmid: 11750768
references.citation: Psychiatry Res. 1989 Nov;30(2):137-44
references.pmid: 2616683
references.citation: Dev Psychobiol. 2007 Nov;49(7):692-701
references.pmid: 17943979
references.citation: Alcohol Clin Exp Res. 1986 Jan-Feb;10(1):33-8
references.pmid: 3515989
references.citation: Life Sci. 1992;50(17):1201-5
references.pmid: 1569828