title: The peptidylglycine alpha-amidating monooxygenase (PAM): a novel prodrug strategy for amidoximes and N-hydroxyguanidines?
authors.affiliation: Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Gutenbergstrasse 76, 24118 Kiel (Germany).
authors.forename: Dennis
authors.initials: D
authors.lastname: Schade
authors.forename: Joscha
authors.initials: J
authors.lastname: Kotthaus
authors.forename: Helen
authors.initials: H
authors.lastname: Hungeling
authors.forename: Jürke
authors.initials: J
authors.lastname: Kotthaus
authors.forename: Bernd
authors.initials: B
authors.lastname: Clement
mesh_terms: D000818:Animals; D006146:Guanidines / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D006898:Hydroxylamines; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009097:Multienzyme Complexes / Q000378:metabolism*; D010091:Oximes / Q000737:chemistry / Q000378:metabolism*; D011355:Prodrugs / Q000737:chemistry / Q000378:metabolism*
chemical_list: D006146:Guanidines; D006898:Hydroxylamines; D009097:Multienzyme Complexes; D010091:Oximes; D011355:Prodrugs; C029604:hydroxyguanidine; D006899:Mixed Function Oxygenases; C035189:peptidylglycine monooxygenase