title: Palmar hyperhidrosis: long-term follow-up of nine children and adolescents treated with botulinum toxin type A.
abstract: Primary palmar hyperhidrosis in children and adolescents may be severe enough to affect school and physical activities, causing emotional problems, stress in the patient's life, and a compromised quality of life. Nine patients with palmar hyperhidrosis underwent treatment with botulinum A. Before the session, and in the 1-, 3-, 6-, 9-, and 12-month post-session follow-ups, the patients were administered the Minor test, gravimetry, the Scales of Frequency and Severity, and the Questionnaire of Quality of Life. The mean age was 11 years, with seven girls and two boys. Each patient was administered at least one treatment of botulinum toxin in the palm of the hands (75-150 U for palm), with the mean number of sessions 2.2 (range: 1-4). All sessions in the patients resulted in drying of the hands, with a mean duration of effect of 7 months. Botulinum toxin A controls excessive sweat in the palms of children and adolescents who have primary palmar hyperhidrosis, with an improvement in the quality of life. The therapy is safe and effective in this pediatric group and can be considered before surgical interventions.
authors.affiliation: Pediatric Department of the Federal University of Paraná, Paraná, Brazil. luciacoutinho@ufpr.br
authors.forename: Lúcia H
authors.initials: LH
authors.lastname: Coutinho dos Santos
authors.forename: Ariadne Miranda
authors.initials: AM
authors.lastname: Gomes
authors.forename: Susana
authors.initials: S
authors.lastname: Giraldi
authors.forename: Kerstin Taniguchi
authors.initials: KT
authors.lastname: Abagge
authors.forename: Leide Parolim
authors.initials: LP
authors.lastname: Marinoni
mesh_terms: D000287:Administration, Topical; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006225:Hand; D006801:Humans; D006945:Hyperhidrosis / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D007223:Infant; D007455:Iodine; D008297:Male; D011788:Quality of Life; D012720:Severity of Illness Index; D013213:Starch; D016896:Treatment Outcome
chemical_list: D013213:Starch; D007455:Iodine; D019274:Botulinum Toxins, Type A