A millisecond micromixer via single-bubble-based acoustic streaming.
We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble-based acoustic streaming. The device operates by trapping an air bubble within a "horse-shoe" structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bubble at its resonance frequency, resulting in acoustic streaming, which disrupts the laminar flows and triggers the two fluids to mix. Due to this technique's simple design, excellent mixing performance, and fast mixing speed (a few milliseconds), our single-bubble-based acoustic micromixer may prove useful for many biochemical studies and applications.
Ahmed
Daniel
D
Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Mao
Xiaole
X
Shi
Jinjie
J
Juluri
Bala Krishna
BK
Huang
Tony Jun
TJ
D000161:Acoustic Stimulation; D000465:Algorithms; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004867:Equipment Design; D044085:Microfluidics / Q000295:instrumentation*; D010316:Particle Size; D013500:Surface Tension
D004129:Dimethylpolysiloxanes; C013830:baysilon