title: Gallbladder cancer manifesting as recurrent common bile duct stone and duodenal ulcer bleeding.
abstract: Gallbladder cancer (GBC) is an uncommon disease and is usually asymptomatic. Poor prognosis and high mortality rate have been noted in patients with delayed diagnosis. We report a case of locally advanced GBC with duodenum and colon invasion manifesting as bleeding duodenal ulcer and recurrent common bile duct (CBD) stones. The patient was successfully treated with extended surgery. In patients who have multiple recurrence of CBD stones without common risk factors, concomitant biliary tract malignancy should be included in the differential diagnosis.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, and National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
authors.forename: Tzung-Jiun
authors.initials: TJ
authors.lastname: Tsai
authors.forename: Kwok-Hung
authors.initials: KH
authors.lastname: Lai
authors.forename: Ping-I
authors.initials: PI
authors.lastname: Hsu
authors.forename: Cheng-Chung
authors.initials: CC
authors.lastname: Tsai
authors.forename: Ting-Ying
authors.initials: TY
authors.lastname: Fu
mesh_terms: D000368:Aged; D002760:Cholangiopancreatography, Endoscopic Retrograde; D004381:Duodenal Ulcer / Q000209:etiology*; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D042882:Gallstones / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D012008:Recurrence; D014057:Tomography, X-Ray Computed