title: Phylogenetic analysis of a near-full-length sequence of an erythrovirus genotype 3 strain isolated in Brazil.
abstract: Human parvovirus B19 is the only member of the genus Erythrovirus that causes human disease. Recent findings of several strains with considerable sequence divergence from B19 have suggested a new classification for parvovirus genotypes as 1 (B19), 2 (A-6 and LaLi) and 3 (V9). In their overall DNA sequence, the three genotypes differ by approximately 10%. Here, we report the isolation of a genotype-3-related strain named BR543 during a prospective study conducted in Sao Paulo, Brazil. Analysis of the nearly full-length genome sequence of BR543 indicates that this B19 variant sequence clusters with Gh2768, a strain from Ghana belonging to subtype 3b, and showed mostly synonymous substitutions.
authors.affiliation: Institute of Biomedical Science, Department of Microbiology, University of Sao Paulo, Prof. Lineu Prestes 1374, Sao Paulo, Brazil. lilian.keller@usp.br
authors.forename: Lilian Walsh
authors.initials: LW
authors.lastname: Keller
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Barbosa
authors.forename: Fernando Lucas
authors.initials: FL
authors.lastname: Melo
authors.forename: Lilian M
authors.initials: LM
authors.lastname: Pereira
authors.forename: Elias
authors.initials: E
authors.lastname: David-Neto
authors.forename: Luiz E
authors.initials: LE
authors.lastname: Lanhez
authors.forename: Edison Luiz
authors.initials: EL
authors.lastname: Durigon
mesh_terms: D001483:Base Sequence; D001938:Brazil; D019218:Erythrovirus / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics; D016679:Genome, Viral / Q000235:genetics; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000821:virology; D016732:Parvovirus B19, Human / Q000235:genetics; D010802:Phylogeny