title: [Vacuum assisted closure (VAC) in the treatment of advanced diabetic foot].
abstract: BACKGROUND
  Deep diabetic foot lesions pose an enormous therapeutic problem. The purpose of this study was to present the experience of the use of vacuum assisted closure (VAC) in the treatment of advanced and complicated diabetic foot lesions.
  
  
  METHODS
  Five cases of advanced diabetic foot that were treated with VAC were prospectively studied. Three patients were diagnosed with renal failure, including one with renal transplant, who were receiving immunosuppression therapy. Four patients had undergone local foot surgery. The foot lesions were classified as grade 3 or 4 according to the Wagner classification. In all patients extensive debridement was performed that resulted in open minor amputations in four cases and resection of the metatarsophalangeal joint in one case. The VAC was applied during the same procedure. The median follow-up period of the patients was 9 months.
  
  
  RESULTS
  Foot salvage was achieved in all cases. The median number of changes of VAC was 16 within median period of 8 weeks. Half of the changes were performed as an outpatient procedure. There were no major complications or clinical signs of infection observed. In one case before treatment with VAC began, angioplasty of the iliac artery and superficial femoral artery was performed. Other interventions carried out after the treatment was started were, two distal revascularizations and two partial transmetatarsal amputations.
  
  
  CONCLUSIONS
  VAC appears to be very useful in the treatment of advanced diabetic foot lesions.
authors.affiliation: Clínica Universidad de Navarra, Pamplona, España. ldzieciuchow@unav.es
authors.forename: Lukasz
authors.initials: L
authors.lastname: Dzieciuchowicz
authors.forename: Gaudencio
authors.initials: G
authors.lastname: Espinosa
authors.forename: Lukasz
authors.initials: L
authors.lastname: Grochowicz
mesh_terms: D000368:Aged; D017719:Diabetic Foot / Q000628:therapy*; D018450:Disease Progression; D006801:Humans; D054843:Negative-Pressure Wound Therapy; D011446:Prospective Studies