title: Formation of xanthine and the use of purine metabolites as a nitrogen source in Arabidopsis plants.
abstract: In our recent paper in The Plant Journal,1 we described the remobilization of purine metabolites during natural and dark induced senescence in wild type and Atxdh1 mutant lines impaired in xanthine dehydrogenase (XDH), a pivotal enzyme in the purine catabolism pathway. In the light of these observations and additional evidence shown here, we discuss the probable pathways leading to xanthine synthesis in Arabidopsis plants during senescence and the role that purine metabolites play as an ongoing source of nitrogen in plant growth.
authors.affiliation: The Jacob Blaustein Institutes for Desert Research; The Albert Katz Department of Dryland Biotechnologies; Ben-Gurion University; Beer Sheva Israel.
authors.forename: Galina
authors.initials: G
authors.lastname: Brychkova
authors.forename: Robert
authors.initials: R
authors.lastname: Fluhr
authors.forename: Moshe
authors.initials: M
authors.lastname: Sagi
references.citation: Plant J. 2008 May;54(3):496-509
references.pmid: 18266920
references.citation: Biochem J. 1980 Jan 15;186(1):343-50
references.pmid: 6154458
references.citation: Plant Physiol. 2007 Jun;144(2):575-81
references.pmid: 17556520
references.citation: Plant Physiol. 1979 Jan;63(1):100-4
references.pmid: 16660656
references.citation: Plant Cell. 2002 Apr;14(4):847-56
references.pmid: 11971139
references.citation: Plant Physiol. 2004 Mar;134(3):1039-49
references.pmid: 14976234
references.citation: Free Radic Biol Med. 2002 Sep 15;33(6):774-97
references.pmid: 12208366
references.citation: Plant Cell Physiol. 2007 Oct;48(10):1484-95
references.pmid: 17872919
references.citation: Annu Rev Plant Biol. 2006;57:805-36
references.pmid: 16669783
references.citation: Plant J. 2005 Jun;42(6):862-76
references.pmid: 15941399
references.citation: Planta. 2006 Apr;223(5):1108-13
references.pmid: 16496096
references.citation: Plant Physiol. 1995 Apr;107(4):1097-103
references.pmid: 7770520
references.citation: Plant Cell. 2007 Oct;19(10):3170-93
references.pmid: 17951448