Capecitabine-induced pancreatitis.
Capecitabine is an oral pro-drug of fluorouracil, which is a commonly used cytotoxic drug in the treatment of colorectal carcinoma. Many adverse effects are known to occur with capecitabine including diarrhea, palmar-planter erythrodysesthesia and nausea. We report a case of capecitabine-induced pancreatitis, also occurring with re-challenge.
Yucel
Hanifi
H
Department of Internal Medicine, Catharina Hospital, Michelangelolaan 2, NL-5602 ZA, Eindhoven, The Netherlands. Hanifi.yucel@cze.nl
Warmerdam
Laurence V
LV
D000328:Adult; D000069287:Capecitabine; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis*; D012811:Sigmoid Neoplasms / Q000188:drug therapy / Q000601:surgery
D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil