title: Psychopathology and personality traits in psychotic patients and their first-degree relatives.
abstract: Personality dimensions have been associated with symptoms dimensions in schizophrenic patients (SP). In this paper we study the relationships between symptoms of functional psychoses and personality dimensions in SP and their first-degree relatives (SR), in other psychotic patients (PP) and their first-degree relatives (PR), and in healthy controls in order to evaluate the possible clinical dimensionality of these disorders. Twenty-nine SP, 29 SR, 18 PP, 18 PR and 188 controls were assessed using the temperament and character inventory (TCI-R). Current symptoms were evaluated with positive and negative syndrome scale (PANSS) using the five-factor model described previously (positive [PF], negative [NF], disorganized [DF], excitement [EF] and anxiety/depression [ADF]). Our TCI-R results showed that patients had different personality dimensions from the control group, but in relatives, these scores were not different from controls. With regard to symptomatology, we highlight the relations observed between harm avoidance (HA) and PANSS NF, and between self-transcendence (ST) and PANSS PF. From a personality traits-genetic factors point of view, schizophrenia and other psychosis may be initially differentiated by temperamental traits such as HA. The so-called characterial traits like ST would be associated with the appearance of psychotic symptoms.
authors.affiliation: Unitat de Psiquiatria i Psicologia Mèdica, Department Medicina i Cirurgia, Fac. Medicina i Ciències de la Salut, Universitat Rovira i Virgili, C/ Sant Llorenç 21, 43201 Reus, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Cortés
authors.forename: J
authors.initials: J
authors.lastname: Valero
authors.forename: J A
authors.initials: JA
authors.lastname: Gutiérrez-Zotes
authors.forename: A
authors.initials: A
authors.lastname: Hernández
authors.forename: L
authors.initials: L
authors.lastname: Moreno
authors.forename: M
authors.initials: M
authors.lastname: Jariod
authors.forename: L
authors.initials: L
authors.lastname: Martorell
authors.forename: E
authors.initials: E
authors.lastname: Vilella
authors.forename: A
authors.initials: A
authors.lastname: Labad
mesh_terms: D000328:Adult; D002605:Character; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D040261:Harm Reduction; D006801:Humans; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory / Q000706:statistics & numerical data; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011594:Psychometrics / Q000706:statistics & numerical data; D011599:Psychopathology; D011618:Psychotic Disorders / Q000235:genetics* / Q000523:psychology; D012016:Reference Values; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology; D013694:Temperament