Combination of autologous fascia lata and fat injection into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis.
OBJECTIVE
To apply the technique of injection of a combination of autologous fascia lata and fat into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis and to evaluate the therapeutic effect in 12 patients who underwent the procedure.


METHODS
Retrospective analysis of 12 patients.


METHODS
Academic research.


METHODS
A mixture of autologous fascia lata and fat was injected into the thyroarytenoid muscle of the paralyzed vocal fold in 12 patients.


METHODS
Videolaryngostroboscopy was performed to observe the changes to the vocal fold. The patients' phonatory function before and after surgery was assessed by computerized acoustic analysis and by blinded perceptual evaluation.


RESULTS
Videolaryngostroboscopy demonstrated that the paralyzed vocal folds in these patients were pushed medially after the procedure. Statistically significant improvements were found in the perturbation measurements (jitter and shimmer), harmonics to noise ratio, and maximum phonation time. Ratings by a panel of voice experts also showed each voice to be statistically significantly improved after the procedure. No complications were noted.


CONCLUSIONS
A combination of autologous fascia lata and fat injected into the vocal fold for unilateral vocal fold paralysis is a safe and effective therapy.
Cheng
You
Y
Department of Otolaryngology-Head and Neck Surgery, Jinling Hospital, Clinical Medical College of Nanjing University, 305 E Zhongshan Road, Nanjing, China.
Li
Ze-qing
ZQ
Huang
Jin-zhong
JZ
Xue
Fei
F
Jiang
Man-jie
MJ
Wu
Kun-min
KM
Wang
Qiu-ping
QP
D000273:Adipose Tissue / Q000637:transplantation*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005206:Fascia Lata / Q000637:transplantation*; D005260:Female; D006801:Humans; D007267:Injections; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014741:Video Recording; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000601:surgery