title: Similar ongoing pregnancy rates after blastocyst transfer in fresh donor cycles and autologous cycles using cryopreserved bipronuclear oocytes suggest similar viability of transferred blastocysts.
abstract: This retrospective cohort study compared blastocyst transfers in 136 fresh oocyte donor cycles and 69 autologous cycles using blastocysts derived from culture of thawed bipronuclear oocytes, all with oocytes derived from patients or donors less than 35 years old. The autologous cycles and oocyte donor cycles had similar rates of implantation (65.9% vs. 62.1%, respectively) and ongoing pregnancy (79.7% vs. 75.0%, respectively), suggesting that autologous blastocysts transferred after post-thaw extended culture have viability and implantation potential that are comparable with those of blastocysts transferred in fresh oocyte donor cycles.
authors.affiliation: Fertility Center of Las Vegas, University of Nevada School of Medicine, Las Vegas, Nevada 89117, USA. bsshapiro@aol.com
authors.forename: Bruce S
authors.initials: BS
authors.lastname: Shapiro
authors.forename: Said T
authors.initials: ST
authors.lastname: Daneshmand
authors.forename: Forest C
authors.initials: FC
authors.lastname: Garner
authors.forename: Martha
authors.initials: M
authors.lastname: Aguirre
authors.forename: Cynthia
authors.initials: C
authors.lastname: Hudson
authors.forename: Shyni
authors.initials: S
authors.lastname: Thomas
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D015925:Cryopreservation; D046149:Embryo Culture Techniques; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000009:adverse effects; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D050498:Live Birth; D018587:Oocyte Donation; D009865:Oocytes; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome