title: Dentin hypersensitivity: a randomized clinical comparison of three different agents in a short-term treatment period.
abstract: OBJECTIVE
  Dentin hypersensitivity, or what patients may describe as "sensitive teeth," is defined as a short, sharp pain arising from exposed dentin in response to thermal, evaporative, tactile, electrical, osmotic or chemical stimuli. It is widely accepted that dentin hypersensitivity is an uncomfortable condition that also affects function and quality of life. This study determines the differences in efficiency of three desensitizing products when compared with a placebo.
  
  
  METHODS
  A randomized controlled clinical trial was conducted to compare three different professional dentin desensitizer agents in 52 patients. The age and sex of the patients was recorded. Gluma Desensitizer (Heraeus Kulzer), UltraEZ (Ultradent Products, Inc) and Duraphat (Colgate Oral Pharmaceuticals, Inc, New York, NY, USA) were used as desensitizer agents and distilled water was used as the placebo. The baseline measurement of the dentin hypersensitivity was made by using a visual analog scale (VAS). Twenty-four hours and seven days after application of the desensitizer agents and placebo, a new VAS analysis was conducted for patients' sensitivity level. The desensitizer agents were compared in terms of mean values, and ANOVA was used for testing differences among the groups (p<0.05).
  
  
  RESULTS
  The results showed that the mean pain scores of the placebo group were significantly higher than that of the study groups (p<0.05). The VAS analysis revealed a significant decrease in dentin hypersensitivity over time with the use of agents (p<0.05). No statistically significant difference was found among the three desensitizing agents (p>0.05).
  
  
  CONCLUSIONS
  These three desensitizing agents, which contain different active ingredients, were effective in relieving dentin hypersensitivity. However, no superiority was found in dentin sensitivity relief among the agents.
authors.affiliation: Department of Oral Diagnosis and Radiology, School of Dentistry, Gülhane Military Medical Academy, Ankara, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Ozen
authors.forename: K
authors.initials: K
authors.lastname: Orhan
authors.forename: H
authors.initials: H
authors.lastname: Avsever
authors.forename: Y M
authors.initials: YM
authors.lastname: Tunca
authors.forename: A E
authors.initials: AE
authors.lastname: Ulker
authors.forename: M
authors.initials: M
authors.lastname: Akyol
mesh_terms: D000293:Adolescent; D000328:Adult; D003807:Dentin Sensitivity / Q000188:drug therapy*; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D005976:Glutaral / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008689:Methacrylates / Q000627:therapeutic use*; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000627:therapeutic use*; D012969:Sodium Fluoride / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D005460:Fluorides, Topical; D008689:Methacrylates; D009566:Nitrates; D017680:Potassium Compounds; C489164:UltraEZ; C111486:gluma desensitizer; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride; D005976:Glutaral