title: Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy.
abstract: OBJECTIVE
  In this study, the effects of intravenous paracetamol treatment on early postoperative period analgesia and recovery characteristics after laparoscopic cholecystectomy have been evaluated.
  
  
  METHODS
  Forty patients whose American Society of Anesthesiologists physical status I or II underwent laparoscopic cholecystectomy and randomly divided into 2 equal groups. In the first group, 1 g paracetamol was given to the patients intravenously after intubation before start of the surgery in 15 minutes. The 100 mL 0.9% NaCl was infused intravenously for the control group in 15 minutes. Postoperative pain was evaluated and recovery characteristics were evaluated.
  
  
  RESULTS
  Verbal and visual pain scores of the paracetamol group were significantly lower than control group (P<0.05). First morphine requirement and total administered morphine dose and duration of staying in recovery room were significantly decreased in the paracetamol group (P<0.05).
  
  
  CONCLUSIONS
  Beside its effective analgesic properties, paracetamol administration during per operative period supports effective and faster recovery.
authors.affiliation: Department of Anesthesiology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Ziya
authors.initials: Z
authors.lastname: Salihoglu
authors.forename: Murat
authors.initials: M
authors.lastname: Yildirim
authors.forename: Sener
authors.initials: S
authors.lastname: Demiroluk
authors.forename: Guner
authors.initials: G
authors.lastname: Kaya
authors.forename: Adem
authors.initials: A
authors.lastname: Karatas
authors.forename: Metin
authors.initials: M
authors.lastname: Ertem
authors.forename: Erman
authors.initials: E
authors.lastname: Aytac
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage*; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D017081:Cholecystectomy, Laparoscopic; D006801:Humans; D007262:Infusions, Intravenous; D010149:Postoperative Pain / Q000188:drug therapy*; D020127:Recovery of Function
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen