Role of LINC proteins in plant nuclear morphology.
A common fate of post-mitotic interphase plant nuclei is morphological differentiation into an array of shapes and sizes. Development of nuclear morphology occurs in a cell-specific manner and is influenced by cell shape and nuclear DNA content. The LINC (LITTLE NUCLEI) proteins are plant-specific nuclear coiled-coil proteins that appear to couple nuclear development to cellular (shape) and nuclear (DNA content) cues. linc mutations cause a variety of defects, including smaller more spherical nuclei and whole-plant dwarfing. Supplementing our previous results, we constructed transgenic plants expressing LINC1-GFP from the native promoter and found that LINC1 is predominantly expressed in proliferating tissues. Moreover, LINC1-GFP signal was found to be concentrated at the nuclear periphery. These results suggest that LINC1 plays an important structural role at an early stage in nuclear development.
Dittmer
Travis A
TA
Department of Biology; Washington University; St. Louis, Missouri USA.
Richards
Eric J
EJ
Plant Physiol. 1991 Jul;96(3):985-9
16668285
Planta. 2004 Jan;218(3):327-36
14610677
Nat Rev Mol Cell Biol. 2005 Jan;6(1):21-31
15688064
Plant J. 1998 Dec;16(6):735-43
10069079
Mol Biol Cell. 2000 Aug;11(8):2733-41
10930466
Genes Dev. 2002 Mar 1;16(5):533-47
11877373
Plant Physiol. 2004 Mar;134(3):927-39
15020757
Mol Biol Cell. 2004 Jun;15(6):2664-73
15034145
J Exp Bot. 2007;58(1):27-34
16804054
Exp Cell Res. 1997 Apr 10;232(1):173-81
9141634
Int Rev Cytol. 2003;226:1-62
12921235
Curr Opin Plant Biol. 2003 Dec;6(6):544-53
14611952
Plant Physiol. 2003 Oct;133(2):462-9
14555774
Plant Cell. 2007 Sep;19(9):2793-803
17873096