Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea.
The bla(CMY-10) gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of bla(CMY-10). A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of bla(CMY-10.).
Song
J S
JS
Department of Biological Sciences, Drug Resistance Proteomics Laboratory, Myongji University, Yongin, Gyeonggido, Korea.
Jang
S J
SJ
Lee
J J
JJ
Lee
J H
JH
Bae
I K
IK
Jeong
B C
BC
Cha
S-S
SS
Lee
J-H
JH
Hong
S-K
SK
Lee
S H
SH
D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D021902:Enterobacter aerogenes / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D004926:Escherichia coli / Q000235:genetics; D005798:Genes, Bacterial; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D056910:Republic of Korea; D017422:Sequence Analysis, DNA; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
D004269:DNA, Bacterial; C491822:CMY-10 beta-lactamase; D001618:beta-Lactamases