The mucosal firewalls against commensal intestinal microbes.
Mammals coexist with an extremely dense microbiota in the lower intestine. Despite the constant challenge of small numbers of microbes penetrating the intestinal surface epithelium, it is very unusual for these organisms to cause disease. In this review article, we present the different mucosal firewalls that contain and allow mutualism with the intestinal microbiota.
Macpherson
Andrew J
AJ
DKF, Maurice Müller Laboratories, Department of Visceral Surgery and Medicine, University of Bern, Room G801, Bern, Switzerland. andrew.macpherson@insel.ch
Slack
Emma
E
Geuking
Markus B
MB
McCoy
Kathy D
KD
D000818:Animals; D054884:Host-Pathogen Interactions / Q000276:immunology*; D006801:Humans; D007410:Intestinal Diseases / Q000276:immunology* / Q000382:microbiology*; D007413:Intestinal Mucosa / Q000276:immunology* / Q000382:microbiology*
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