title: Statistical validation of a new helical tomotherapy patient transfer station.
abstract: The purpose of this work is to evaluate statistically the accuracy of a patient transfer station (PTS, TomoTherapy Inc., Madison, WI) that automatically converts one planning-station-generated treatment plan to another one with a different beam model. In our department we have installed 2 HI*ART tomotherapy systems, and patients often need to be transferred from one tomotherapy unit to the other. Thirty patients who underwent patient transfer between the two systems were evaluated. For each patient, dose differences between his/her original plan and PTS-transferred plan were evaluated by comparing doses at 10 randomly selected positions in his/her CT images. The Pearson indexes were calculated to analyze the relationship of the deviations to other parameters, which include absolute dose levels, sites (targets or normal tissues), dose accuracy of original plans and that of transferred plans. The dose accuracy of a treatment plan was determined by comparing delivered doses at the center of a 30 cm x 30 cm x 12 cm solid water phantom to planned doses at the same position. The calculated dose difference between original and transferred plans was, on average, 0.8% +/- 0.5%; the maximum deviation in absolute values was 1.9% in target volumes and 2.5% in normal organs. The errors generated during PTS-based transferring process were random and did not show correlation with other parameters. The PTS took less than 10 minutes to generate a backup plan that is much less than 2 hours that is approximately needed to create a duplicate plan manually. The results show that a PTS-transferred plan is an acceptable match to the original plan. With a physician's approval, a transferred plan is acceptable for treatment without the necessity of being revalidated in phantom. Thus far, all of our PTS plans have been approved by the treating physician without further optimization.
authors.affiliation: Department of Radiation Oncology, City of Hope Cancer Center, Duarte, California, USA.
authors.forename: Audrey H
authors.initials: AH
authors.lastname: Zhuang
authors.affiliation: Department of Radiation Oncology, City of Hope Cancer Center, Duarte, California, USA.
authors.forename: An
authors.initials: A
authors.lastname: Liu
authors.affiliation: Department of Radiation Oncology, City of Hope Cancer Center, Duarte, California, USA.
authors.forename: Timothy E
authors.initials: TE
authors.lastname: Schultheiss
authors.affiliation: Department of Radiation Oncology, City of Hope Cancer Center, Duarte, California, USA.
authors.forename: Jeffrey Y C
authors.initials: JYC
authors.lastname: Wong
mesh_terms: D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging; D011880:Radiotherapy Planning, Computer-Assisted; D036542:Tomography, Spiral Computed / Q000379:methods*; D014187:Transportation of Patients
references.citation: Semin Radiat Oncol. 1999 Jan;9(1):108-17
references.pmid: 10196402
references.citation: Med Phys. 2007 Jul;34(7):2917-27
references.pmid: 17822000
references.citation: Med Phys. 1993 Nov-Dec;20(6):1709-19
references.pmid: 8309444