title: Melasma: a clinicopathological study of 43 cases.
abstract: Melasma is a symmetrical hypermelanosis of the exposed skin characterized by brown macules on the sun-exposed areas of the skin. The present study was carried out on 43 patients to analyze the correlation between histopathological features with clinical and Wood's light examination. The study showed a clinical and histopathological discordance of 16.2%. Solar elastosis (55.8%) was the single most common histological finding apart from increased melanin concentration, epidermal flattening and dermal lymphomononuclear inflammation.
authors.affiliation: Institute of Pathology-ICMR, New Delhi, India.
authors.forename: Vermani
authors.initials: V
authors.lastname: Sarvjot
authors.forename: Shruti
authors.initials: S
authors.lastname: Sharma
authors.forename: Sharmila
authors.initials: S
authors.lastname: Mishra
authors.forename: Avninder
authors.initials: A
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D000328:Adult; D004549:Elastin / Q000032:analysis; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008297:Male; D008543:Melanins / Q000032:analysis; D008548:Melanosis / Q000473:pathology* / Q000503:physiopathology*; D008875:Middle Aged; D012867:Skin / Q000473:pathology*; D055815:Young Adult
chemical_list: D008543:Melanins; D004549:Elastin