Too fat to fly? New brain circuits regulate obesity in Drosophila.
In mammals, fat store levels are regulated by brain centers that control food intake and metabolism. A new study by Al-Anzi and colleagues in this issue of Neuron identifies neurons with similar functions in Drosophila, further establishing the fly as a legitimate model to study obesity.
Kaun
Karla R
KR
Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143-2822, USA.
Heberlein
Ulrike
U
D000818:Animals; D001921:Brain / Q000473:pathology / Q000502:physiology*; D004195:Disease Models, Animal; D004330:Drosophila / Q000235:genetics / Q000502:physiology*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D009415:Nerve Net / Q000473:pathology / Q000502:physiology*; D009474:Neurons / Q000145:classification / Q000473:pathology / Q000502:physiology*; D009765:Obesity / Q000235:genetics / Q000378:metabolism* / Q000503:physiopathology
D029721:Drosophila Proteins