title: Comparison of intravenous general anaesthesia vs endotracheal intubation in the surgical management of juvenile onset recurrent respiratory papillomatosis.
abstract: CONCLUSIONS
  Both intravenous general anaesthesia (IVGA) and general anaesthesia with endotracheal intubation (GA with ET) are applicable for the procedure of juvenile onset recurrent respiratory papillomatosis (JO-RRP). GA with ET was found to be better for JO-RRP patients with dyspnoea, as it provided better stabilization of the vital signs with fewer postoperative complications.
  
  
  OBJECTIVE
  To evaluate the safety and efficacy of two different anaesthetic techniques in the removal of JO-RRP.
  
  
  METHODS
  A total of 52 JO-RRP patients with mild dyspnoea were included in the study. Each case underwent two procedures, one by IVGA and the other by GA with ET. A total of 104 procedures were performed. The effectiveness and safety of the two anaesthetic techniques were pairwise compared.
  
  
  RESULTS
  There were no significant differences in anaesthetic recovery time, operative time or postoperative voice quality between the two anaesthetic groups. However, significant differences in heart rate, oxygen saturation and carbon dioxide saturation were observed. Some patients who underwent IVGA developed apnoea (28.8%) and laryngeal spasm (19.2%). These complications were not observed in the GA with ET group.
authors.affiliation: National Key Disciplines of Otorhinolaryngology, Otorhinolaryngology Hospital, Otorhinolaryngology Institute, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China.
authors.forename: Wenbin
authors.initials: W
authors.lastname: Lei
authors.forename: Weiping
authors.initials: W
authors.lastname: Wen
authors.forename: Zhenzhong
authors.initials: Z
authors.lastname: Su
authors.forename: Liping
authors.initials: L
authors.lastname: Chai
authors.forename: Xia
authors.initials: X
authors.lastname: Feng
authors.forename: Kexuan
authors.initials: K
authors.lastname: Liu
authors.forename: Aiyun
authors.initials: A
authors.lastname: Jiang
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000768:Anesthesia, General / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D003646:Debridement / Q000379:methods*; D004417:Dyspnea / Q000453:epidemiology; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D007830:Larynx; D008297:Male; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010212:Papilloma / Q000453:epidemiology / Q000601:surgery*; D012008:Recurrence
chemical_list: D018686:Anesthetics, Intravenous