Unexpectedly high AUC levels in a child who received intravenous busulfan before stem cell transplantation.
Nishikawa
T
T
Okamoto
Y
Y
Tanabe
T
T
Shinkoda
Y
Y
Kodama
Y
Y
Higashi
M
M
Hirano
H
H
Arita
K
K
Kawano
Y
Y
D019540:Area Under Curve; D002066:Busulfan / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics*; D002528:Cerebellar Neoplasms / Q000628:therapy; D002648:Child; D016903:Drug Monitoring; D017809:Fatal Outcome; D005982:Glutathione Transferase / Q000235:genetics / Q000378:metabolism; D006801:Humans; D007275:Injections, Intravenous; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008297:Male; D008527:Medulloblastoma / Q000628:therapy; D019653:Myeloablative Agonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics*; D036102:Peripheral Blood Stem Cell Transplantation; D019172:Transplantation Conditioning / Q000009:adverse effects*; D014182:Transplantation, Autologous
D019653:Myeloablative Agonists; C484555:GSTA1 protein, human; D005982:Glutathione Transferase; D002066:Busulfan