The rabbit as an animal model for experimental surgery.
The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.
Calasans-Maia
Mônica Diuana
MD
Cell Therapy Center, University Hospital Antonio Pedro, Fluminense Federal University, Niteroi, RJ, Brazil. monicacalasans@terra.com.br
Monteiro
Maria Lucia
ML
Ascoli
Fábio Oliveira
FO
Granjeiro
José Mauro
JM
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D011817:Rabbits; D013514:Surgical Procedures, Operative