Reduction in hepatitis B virus seroprevalence among U.S.-born children of foreign-born Asian parents -- benefit of universal infant hepatitis B vaccination.
We demonstrate that after implementation of recommendations for universal infant hepatitis B vaccination, HBV infection prevalence among children of foreign-born Asian parents in Georgia declined dramatically; horizontal transmission of infection within households has occurred infrequently; and the vast majority of infants and children have received the recommended hepatitis B vaccinations. These results provide evidence of the success of the hepatitis B infant vaccination program and highlight its potential impact on reducing chronic HBV infection morbidity and mortality among U.S. populations at high risk.
Shuler
Carrie M
CM
Notifiable Diseases Epidemiology Section, Georgia Department of Human Resources, Division of Public Health, Atlanta, GA, United States. carrie dogcat@yahoo.com
Fiore
Anthony E
AE
Neeman
Ruth
R
Bell
Beth P
BP
Kuhnert
Wendi
W
Watkins
Sandra
S
Kilgour
Kimberly
K
Arnold
Kathryn E
KE
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000208:ethnology; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D005845:Georgia / Q000453:epidemiology; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D017325:Hepatitis B Vaccines / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D055815:Young Adult
D006508:Hepatitis Antibodies; D017325:Hepatitis B Vaccines