title: Diffusion-weighted imaging and ADC mapping of head-and-neck paragangliomas: initial experience.
abstract: BACKGROUND
  Paragangliomas are rare, hypervascularized benign tumors. In some cases a clear differentiation of paragangliomas and other entities is impossible.
  
  
  METHODS
  The authors evaluated ten patients with skull base lesions (paraganglioma n = 7, meningioma n = 1, giant cell tumor n = 1, and neurinoma n = 1) in addition to conventional magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), and calculation of apparent diffusion coefficient (ADC).
  
  
  RESULTS
  Mean ADC values +/- standard deviation of the paragangliomas were 1.304 +/- 0.257 x 10(-3) mm(2)/s and differed from ADC values of the other jugular fossa tumors with 0.743 +/- 0.108 x 10(-3) mm(2)/s and measurement derived from the cerebellum with 0.802 +/- 0.075 x 10(-3) mm(2)/s.
  
  
  CONCLUSIONS
  Due to the difference of ADC values, the authors propose that DWI and ADC mapping could be a promising tool in the diagnostic work-up of paragangliomas.
authors.affiliation: Department of Diagnostic and Interventional Radiology and Neuroradiology, HELIOS Klinikum Erfurt GmbH, Erfurt, Germany. rene.aschenbach@helios-kliniken.de
authors.forename: René
authors.initials: R
authors.lastname: Aschenbach
authors.forename: Steffen
authors.initials: S
authors.lastname: Basche
authors.forename: Thomas Josef
authors.initials: TJ
authors.lastname: Vogl
authors.forename: Joachim
authors.initials: J
authors.lastname: Klisch
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D010235:Paraganglioma / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019292:Skull Base Neoplasms / Q000175:diagnosis*
references.citation: AJNR Am J Neuroradiol. 2001 Jun-Jul;22(6):1089-96
references.pmid: 11415903
references.citation: Magn Reson Med. 2002 Aug;48(2):297-305
references.pmid: 12210938
references.citation: AJNR Am J Neuroradiol. 2002 Feb;23(2):322-33
references.pmid: 11847064
references.citation: AJNR Am J Neuroradiol. 2001 Jun-Jul;22(6):1081-8
references.pmid: 11415902
references.citation: AJNR Am J Neuroradiol. 2004 Nov-Dec;25(10):1653-8
references.pmid: 15569726
references.citation: AJNR Am J Neuroradiol. 2005 Mar;26(3):630-4
references.pmid: 15760877
references.citation: Eur J Radiol. 2008 Jun;66(3):493-500
references.pmid: 18337039
references.citation: JAMA. 2004 Aug 25;292(8):943-51
references.pmid: 15328326
references.citation: AJNR Am J Neuroradiol. 2003 Sep;24(8):1627-34
references.pmid: 13679283
references.citation: Magn Reson Med. 2000 Feb;43(2):303-9
references.pmid: 10680696
references.citation: Neuroradiology. 2003 Oct;45(10):681-6
references.pmid: 12942216
references.citation: AJR Am J Roentgenol. 2000 May;174(5):1293-5
references.pmid: 10789780
references.citation: AJNR Am J Neuroradiol. 2000 Nov-Dec;21(10):1830-6
references.pmid: 11110534
references.citation: Eur Radiol. 2003 Jul;13(7):1608-11
references.pmid: 12835974
references.citation: Radiology. 1993 Aug;188(2):339-46
references.pmid: 8327675
references.citation: AJNR Am J Neuroradiol. 2008 Jan;29(1):40-4
references.pmid: 17921228
references.citation: AJNR Am J Neuroradiol. 2002 Mar;23(3):404-7
references.pmid: 11901008
references.citation: AJNR Am J Neuroradiol. 2001 Jan;22(1):60-4
references.pmid: 11158889
references.citation: Int J Radiat Oncol Biol Phys. 2007 Mar 15;67(4):960-71
references.pmid: 17141979
references.citation: Neurosurg Rev. 2006 Jan;29(1):1-11; discussion 12-13
references.pmid: 16283211
references.citation: J Magn Reson Imaging. 2004 Oct;20(4):735-42
references.pmid: 15390151
references.citation: AJNR Am J Neuroradiol. 2002 Apr;23(4):520-7
references.pmid: 11950638
references.citation: Radiology. 2001 Sep;220(3):621-30
references.pmid: 11526259
references.citation: Neuroradiology. 2000 Feb;42(2):104-7
references.pmid: 10663484
references.citation: Eur Radiol. 2000;10(5):736-44
references.pmid: 10823625
references.citation: Rofo. 2005 Jul;177(7):940-5
references.pmid: 15973595
references.citation: Eur Radiol. 2006 Jul;16(7):1468-77
references.pmid: 16557366