[Congenital chylothorax and hypothyroidism: a case report and a review of the literature].
Congenital chylothorax, an uncommon disorder, is a therapeutic challenge without satisfactory results. When classical medical approaches fail (such as thoracosynthesis, total parenteral nutrition, and fasting followed by oral medium-chain triglycerides), some medical teams introduce somatostatin or octreotide in cases of recurring chylothorax. We report a case of recurring chylothorax treated with somatostatin at day 27 correlated with an unfortunate discovery of hypothyroidism on day 34. Clinical signs of chylothorax on somatostatin clearly improved with the introduction of levothyroxine. This article points out the relation between the two diseases based on a review of the literature.
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Service de néonatologie et de réanimation néonatale, hôpital de la Croix-Rousse, hospices civils de Lyon, 103 Grande-Rue-de-la-Croix-Rousse, Lyon cedex 04, France. celinenoseda@yahoo.fr
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D000328:Adult; D002916:Chylothorax / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D015897:Comorbidity; D003409:Congenital Hypothyroidism / Q000175:diagnosis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012008:Recurrence; D019233:Retreatment; D013004:Somatostatin / Q000627:therapeutic use*; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000627:therapeutic use*
D013004:Somatostatin; D013974:Thyroxine