title: Production of autoantibodies to glutamate during Alzheimer's dementia.
abstract: Increased production of autoantibodies to glutamate was found in blood plasma from patients with Alzheimer's dementia. The content of autoantibodies to glutamate in patients with early-onset Alzheimer's disease was much lower than in those with late-onset Alzheimer's disease (1.40+/-0.07 and 1.80+/-0.07 arb. units, p<0.001). The level of autoantibodies to glutamate in patients with mixed - Alzheimer's disease was 1.60+/-0.01 arb. units.
authors.affiliation: Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, N. A. Alekseev Moscow Clinical Psychiatric Hospital No. 1, Moscow. dav-ta@yandex.ru
authors.forename: T V
authors.initials: TV
authors.lastname: Davydova
authors.forename: N I
authors.initials: NI
authors.lastname: Voskresenskaya
authors.forename: V Yu
authors.initials: VY
authors.lastname: Gorbatov
authors.forename: V G
authors.initials: VG
authors.lastname: Fomina
authors.forename: O A
authors.initials: OA
authors.lastname: Doronina
authors.forename: I V
authors.initials: IV
authors.lastname: Maksunova
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000097:blood* / Q000453:epidemiology / Q000276:immunology*; D000704:Analysis of Variance; D001323:Autoantibodies / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D018698:Glutamic Acid / Q000097:blood* / Q000276:immunology*; D006801:Humans
chemical_list: D001323:Autoantibodies; D018698:Glutamic Acid