title: Food protective effect of geraniol and its congeners against stored food mites.
abstract: The acaricidal activities of compounds derived from the oil of Pelargonium graveolens leaves against the storage food mite, Tyrophagus putrescentiae, were compared with the activity of a commercial acaricide, benzyl benzoate, in an impregnated fabric disk bioassay. Purification of the active constituent from P. graveolens was accomplished by silica gel chromatography and high-performance liquid chromatography. Structural analysis of the active constituent by 1H nuclear magnetic resonance (NMR), 13C-NMR, 1H-13C shift correlated spectroscopy NMR, and distortionless enhancement by polarization transfer NMR identified trans-3,7-dimethyl-2,6-octadien-1-ol (geraniol). Based on the 50% lethal dose values, the most toxic compounds against T. putrescentiae were geraniol (1.95 microg/cm3), which was followed by nerol (2.21 microg/cm3), citral (9.65 microg/cm3), benzyl benzoate (11.27 microg/cm3), and beta-citronellol (15.86 microg/cm3). Our results suggest that geraniol is more effective in controlling T. putrescentiae than benzyl benzoate is. Furthermore, geraniol, which is used as a flavoring for beverages, candies, ice creams, and baked goods and congeners (citral and nerol), may be useful for managing populations of T. putrescentiae.
authors.affiliation: Department of Agricultural Chemistry and Institute of Agricultural Science and Technology, College of Agriculture and Life Science, Chonbuk National University, Chonju 561-756, South Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Jeon
authors.forename: C H
authors.initials: CH
authors.lastname: Lee
authors.forename: H S
authors.initials: HS
authors.lastname: Lee
mesh_terms: D040041:Acaridae / Q000187:drug effects* / Q000254:growth & development; D000080462:Acyclic Monoterpenes; D000818:Animals; D001565:Benzoates; D001681:Biological Assay; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D005519:Food Preservation / Q000379:methods*; D007306:Insecticides / Q000494:pharmacology*; D007928:Lethal Dose 50; D039821:Monoterpenes / Q000494:pharmacology; D031316:Pelargonium / Q000737:chemistry*; D010572:Pest Control, Biological / Q000379:methods; D010936:Plant Extracts / Q000494:pharmacology*; D013729:Terpenes / Q000494:pharmacology*
chemical_list: D000080462:Acyclic Monoterpenes; D001565:Benzoates; D007306:Insecticides; D039821:Monoterpenes; D010936:Plant Extracts; D013729:Terpenes; C007836:geraniol; C006723:benzyl benzoate; C007078:citronellol; C007076:citral