title: Repeat mitral valve replacement: 30-years' experience.
abstract: Prosthetic heart valve dysfunction is an acquired condition that carries a significant risk of emergency surgery. However, the long-term natural history of the condition is not well understood. Between 1974 and 2006, 1535 isolated mitral valve replacements were performed at our hospital (in-hospital mortality 5%). In total, 369 patients needed a second operation (in-hospital mortality 8.1%), while 80 (age 59.8+/-11.4 years) needed a third. The reasons for the third intervention were structural deterioration (67.5%), paravalvular leak (20%) and endocarditis (6.3%). Some 15 patients died in hospital (18.8%). After a mean follow-up period of 17.8 years, 21 patients needed another intervention (i.e., a fourth intervention). The actuarial reoperation-free rate at 20 years was 40.1+/-13.8%. The late mortality rate was 58.5% (18-year survival rate 15.4+/-5.4%). Indications for repeat mitral valve replacement must be judged on an individual basis given the high risk associated with surgery.
authors.affiliation: Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Cantabria, Spain. vicast79@hotmail.com
authors.forename: Víctor
authors.initials: V
authors.lastname: Expósito
authors.forename: Tamara
authors.initials: T
authors.lastname: García-Camarero
authors.forename: José M
authors.initials: JM
authors.lastname: Bernal
authors.forename: Elena
authors.initials: E
authors.lastname: Arnáiz
authors.forename: Aurelio
authors.initials: A
authors.lastname: Sarralde
authors.forename: Iván
authors.initials: I
authors.lastname: García
authors.forename: José R
authors.initials: JR
authors.lastname: Berrazueta
authors.forename: José M
authors.initials: JM
authors.lastname: Revuelta
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D012086:Reoperation; D013997:Time Factors