title: Endoscopic submucosal dissection of a minute intramucosal adenocarcinoma in Barrett's esophagus.
abstract: A 73-year-old man with short segmental Barrett's esophagus underwent esophagoscopy, and a slightly depressed, discolored lesion was found on the anterior wall of the lower esophagus. Under a provisional diagnosis of differentiated adenocarcinoma without local lymph node metastasis, endoscopic submucosal dissection (ESD) was carried out. En bloc resection with tumor-free lateral/basal margins was accomplished without complication. The resected area was 12 x 15 mm in size, whereas the neoplastic lesion was 4 x 4 mm. Histopathological examination confirmed intramucosal well-differentiated tubular adenocarcinoma without angiolymphatic invasion adjacent to the muscularis mucosae. Repeated esophagoscopy 6 months after ESD showed neither locally recurrent nor metachronous lesions. Considering that Barrett's esophagus is a precancerous condition, one may recommend eradication of both the neoplastic and non-neoplastic lesion with using ESD.
authors.affiliation: Sasebo Municipal General Hospital, Hirase, Sasebo, Japan.
authors.forename: Koki
authors.initials: K
authors.lastname: Ikeda
authors.forename: Hajime
authors.initials: H
authors.lastname: Isomoto
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Oda
authors.forename: Saburo
authors.initials: S
authors.lastname: Shikuwa
authors.forename: Yohei
authors.initials: Y
authors.lastname: Mizuta
authors.forename: Keisuke
authors.initials: K
authors.lastname: Iwasaki
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology / Q000601:surgery*; D000368:Aged; D001471:Barrett Esophagus / Q000150:complications*; D004938:Esophageal Neoplasms / Q000209:etiology / Q000601:surgery*; D004945:Esophagoscopy; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000601:surgery