Given the complexity of the human genome, can 'personalised medicine' or 'individualised drug therapy' ever be achieved?
Nebert
Daniel W
DW
D004358:Drug Therapy; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D007206:Individuality; D040641:Quantitative Trait Loci
Trends Pharmacol Sci. 2006 Nov;27(11):580-6
17005258
Eur J Pharmacol. 2004 Oct 1;500(1-3):267-80
15464039
N Engl J Med. 2009 Apr 23;360(17):1699-701
19369661
Am J Pharmacogenomics. 2003;3(6):361-70
14672516
Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):34-42
15982695
N Engl J Med. 2009 Apr 23;360(17):1696-8
19369660
N Engl J Med. 2009 Apr 23;360(17):1759-68
19369657
N Engl J Med. 2009 Apr 23;360(17):1701-3
19369656
Drug Metab Rev. 2008;40(2):187-224
18464043