A Golgi-on-a-chip for glycan synthesis.
One of the primary functions of the Golgi apparatus is the assembly of glycans on macromolecules destined for secretion or the plasma membrane. A recent study describes the first step toward an artificial Golgi, based on a microfluidic chip and magnetic nanoparticles.
Xu
Ding
D
Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California-San Diego, La Jolla, California, USA.
Esko
Jeffrey D
JD
D001665:Binding Sites; D006031:Glycosylation; D006056:Golgi Apparatus / Q000201:enzymology / Q000378:metabolism*; D006497:Heparan Sulfate / Q000096:biosynthesis / Q000737:chemistry; D008024:Ligands; D046210:Microfluidic Analytical Techniques; D008954:Models, Biological; D011134:Polysaccharides / Q000096:biosynthesis* / Q000737:chemistry
D006497:Heparan Sulfate; D008024:Ligands; D011134:Polysaccharides
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