title: Interface biology of implants.
abstract: Implants are widely used in various clinical disciplines to replace or stabilize organs. The challenge for the future is to apply implant materials to specifically control the biology of the surrounding tissue for repair and regeneration. This field of research is highly interdisciplinary and combines scientists from technical and life sciences disciplines. To successfully apply materials for regenerative processes in the body, the understanding of the mechanisms at the interface between cells or tissues and the artificial material is of critical importance. The research focuses on stem cells, design of material surfaces, and mechanisms of cell adhesion. For the third time around 200 scientists met in Rostock, Germany for the international symposium "Interface Biology of Implants." The aim of the symposium is to promote the interdisciplinary dialogue between the scientists from the different disciplines to develop smart implants for medical use. In addition, researchers from basic sciences, notably cell biology presented new findings concerning mechanisms of cell adhesion to stimulate research in the applied field of implant technology.
authors.affiliation: Laboratory of Cell Biology, Medical Faculty of the University of Rostock, Rostock, Germany. joachim.rychly@med.uni-rostock.de
authors.forename: Joachim
authors.initials: J
authors.lastname: Rychly
authors.forename: Barbara
authors.initials: B
authors.lastname: Nebe
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002448:Cell Adhesion / Q000502:physiology; D002468:Cell Physiological Phenomena / Q000502:physiology*; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D011108:Polymers / Q000737:chemistry; D019736:Prostheses and Implants; D044968:Regenerative Medicine; D013234:Stem Cells / Q000166:cytology / Q000502:physiology; D013499:Surface Properties; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials; D011108:Polymers
references.citation: J Cell Biol. 2008 Mar 10;180(5):989-1003
references.pmid: 18332220
references.citation: Stem Cells. 2006 Apr;24(4):1042-53
references.pmid: 16373694
references.citation: Endocrinology. 2007 Jul;148(7):3111-21
references.pmid: 17446189
references.citation: Biomaterials. 2006 Jun;27(16):3044-63
references.pmid: 16458351
references.citation: Ann Biomed Eng. 2009 May;37(5):847-59
references.pmid: 19259817
references.citation: J Cell Biol. 2005 Oct 24;171(2):383-92
references.pmid: 16247034
references.citation: Curr Opin Cell Biol. 2009 Feb;21(1):38-46
references.pmid: 19217273
references.citation: Faraday Discuss. 2008;139:229-49; discussion 309-25, 419-20
references.pmid: 19048998
references.citation: Biomaterials. 2008 Jul;29(21):3105-16
references.pmid: 18442852
references.citation: Nat Nanotechnol. 2008 Aug;3(8):465-75
references.pmid: 18685633
references.citation: Biophys J. 2007 Apr 15;92(8):2964-74
references.pmid: 17277192
references.citation: Langmuir. 2007 Jul 3;23(14):7841-6
references.pmid: 17547436
references.citation: Curr Opin Cell Biol. 2008 Dec;20(6):609-15
references.pmid: 18926907
references.citation: Science. 2005 Nov 18;310(5751):1135-8
references.pmid: 16293749
references.citation: Biomaterials. 2009 Feb;30(4):526-34
references.pmid: 18977026
references.citation: Biomaterials. 2008 Jul;29(19):2849-57
references.pmid: 18406458
references.citation: Science. 2007 Aug 3;317(5838):663-6
references.pmid: 17673662
references.citation: Ann Anat. 2009 Jan;191(1):136-44
references.pmid: 19008086
references.citation: Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11450-5
references.pmid: 16055556
references.citation: Curr Opin Cell Biol. 2006 Oct;18(5):472-81
references.pmid: 16930976
references.citation: Nat Rev Mol Cell Biol. 2009 Jan;10(1):21-33
references.pmid: 19197329
references.citation: Nat Mater. 2009 Jun;8(6):457-70
references.pmid: 19458646
references.citation: Cell. 2006 Aug 25;126(4):677-89
references.pmid: 16923388
references.citation: Biomaterials. 2008 Aug;29(22):3221-7
references.pmid: 18456320
references.citation: J Cell Physiol. 2008 Nov;217(2):450-8
references.pmid: 18613064
references.citation: Science. 2009 Apr 10;324(5924):208-12
references.pmid: 19359578
references.citation: Eur J Cell Biol. 2008 Sep;87(8-9):743-50
references.pmid: 18572273
references.citation: Biomaterials. 2007 Sep;28(27):3965-76
references.pmid: 17582491
references.citation: J Biol Chem. 2007 Mar 9;282(10):7339-51
references.pmid: 17182623