Listeria monocytogenes meningitis in two immunocompetent children.
Listeria monocytogenes is an uncommon cause of bacterial meningitis beyond the neonatal period. Patients with immunosuppression or neoplastic disease are at increased risk of developing serious invasive disease, particularly meningitis. L. monocytogenes meningitis in two previously healthy, immunocompetent children aged 7 years and 18 months is described. One of them was successfully treated with ampicillin and amikacin. In the other there was resistance to ampicillin, and meropenem, vancomycin and amikacin were given. One patient developed unilateral abducens paralysis and inappropriate antidiuretic hormone secretion. L. monocytogenes should be suspected in children with bacterial meningitis who fail to respond to empirical antibiotic therapy.
Dilber
E
E
Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, Cocuk Bölümü, Trabzon, Turkey. embiyadilber@yahoo.com
Aksoy
A
A
Cakir
M
M
Bahat
E
E
Kamaşak
T
T
Dilber
B
B
D000583:Amikacin / Q000627:therapeutic use; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination; D006801:Humans; D007121:Immunocompetence; D007223:Infant; D008088:Listeriosis / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008584:Meningitis, Listeria / Q000175:diagnosis* / Q000188:drug therapy; D000077731:Meropenem; D012307:Risk Factors; D013129:Spinal Puncture; D013845:Thienamycins / Q000627:therapeutic use; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D014640:Vancomycin; D000667:Ampicillin; D000583:Amikacin; D000077731:Meropenem