Palladium-catalyzed benzylation of heterocyclic aromatic compounds.
Broadly applicable palladium-catalyzed heteroarene benzylation reactions are described with a focus on the most challenging heterocyclic classes under traditional benzylation techniques such as sulfur-containing heterocycles and those bearing functional groups that would be incompatible with reactions requiring Lewis acids and/or strong bases.
Lapointe
David
D
Center for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, ON, K1N 6J7, Canada.
Fagnou
Keith
K
D001593:Benzyl Compounds / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry
D001593:Benzyl Compounds; D006571:Heterocyclic Compounds; D010165:Palladium; D013455:Sulfur