title: Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea.
abstract: The bla(CMY-10) gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of bla(CMY-10). A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of bla(CMY-10.).
authors.affiliation: Department of Biological Sciences, Drug Resistance Proteomics Laboratory, Myongji University, Yongin, Gyeonggido, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Song
authors.forename: S J
authors.initials: SJ
authors.lastname: Jang
authors.forename: J J
authors.initials: JJ
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
authors.forename: I K
authors.initials: IK
authors.lastname: Bae
authors.forename: B C
authors.initials: BC
authors.lastname: Jeong
authors.forename: S-S
authors.initials: SS
authors.lastname: Cha
authors.forename: J-H
authors.initials: JH
authors.lastname: Lee
authors.forename: S-K
authors.initials: SK
authors.lastname: Hong
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
mesh_terms: D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D021902:Enterobacter aerogenes / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D004926:Escherichia coli / Q000235:genetics; D005798:Genes, Bacterial; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D056910:Republic of Korea; D017422:Sequence Analysis, DNA; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D004269:DNA, Bacterial; C491822:CMY-10 beta-lactamase; D001618:beta-Lactamases