title: Changing prevalence and severity of childhood allergic diseases in kyoto, Japan, from 1996 to 2006.
abstract: BACKGROUND
  Published data regarding changes in the prevalence of childhood allergic diseases in Japan have been limited.
  
  
  METHODS
  To observe changes in the recent trends of the childhood allergy epidemic in Japan, a population-based questionnaire survey of allergic diseases was conducted among 13,215 schoolchildren, aged 7 to 15 years, in Kyoto, Japan in 2006. The results were compared with those obtained in the 1996 survey using the same scale and methods in the same region.
  
  
  RESULTS
  The prevalences of bronchial asthma (BA), atopic dermatitis (AD), allergic rhinitis (AR), and allergic conjunctivitis (AC) in 1996 and 2006 were 5.1% and 5.0% (p = 0.58), 4.2% and 5.6% (p < 0.0001), 20.3% and 27.4% (p < 0.0001), and 13.3% and 25.2% (p < 0.0001), respectively. Although the distribution of BA severity improved, the severity distribution of AD, AR, and AC all deteriorated. The lifetime prevalence (present prevalence and past history combined) of BA increased from 6.5% to 7.6% (p < 0.0001). The sex ratio analysis showed that the female predominance in the prevalence of AD observed in 1996 disappeared in 2006, indicating a particular rise in AD prevalence among boys.
  
  
  CONCLUSIONS
  Overall, the results indicate that the rising trend of allergic diseases, especially in AD, AR, and AC, continues among schoolchildren living in Kyoto, Japan. Special attention should be paid to skin and nasoocular symptoms.
authors.affiliation: Department of Pediatrics, Shiga Medical Center for Children, Shiga, Japan. kusutaka@gamma.ocn.ne.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Kusunoki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Morimoto
authors.forename: Ryuta
authors.initials: R
authors.lastname: Nishikomori
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yasumi
authors.forename: Toshio
authors.initials: T
authors.lastname: Heike
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Fujii
authors.forename: Tatsutoshi
authors.initials: T
authors.lastname: Nakahata
mesh_terms: D000293:Adolescent; D002648:Child; D018450:Disease Progression; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000503:physiopathology*; D007564:Japan; D008297:Male; D015995:Prevalence; D012720:Severity of Illness Index; D012737:Sex Factors; D011795:Surveys and Questionnaires