STH2 has 2 B there: An insight into the role of B-box containing proteins in Arabidopsis.
Recently we reported the identification of a novel B-box transcription factor SALT TOLERANCE HOMOLOG 2 (STH2) that interacts genetically with two key regulators of the light-signaling pathway, HY5 and COP1.1 We also provided phenotypic and genetic characterization of the sth2 mutant suggesting that STH2 plays a positive role in regulating photomorphogenesis both independently or together with HY5. Functional assays in protoplasts revealed that STH2 could act as a transcriptional activator. To our knowledge this is the first report of a B-box domain containing protein playing a direct role in activating transcription in plants. Here we discuss the possible position of STH2 in the transcriptional network and comment on the role of the B-box domain in plants.
Datta
Sourav
S
Department of Cell and Molecular Biology Gothenburg University; Gothenburg, Sweden.
Johansson
Henrik
H
Hettiarachchi
Chamari
C
Holm
Magnus
M
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