Myelopathy and adult T-cell leukemia associated with HTLV-1 in a young patient with hearing loss as the initial manifestation of disease.
A young male developed hearing loss, vertigo, headache and facial palsy. Neurological examination did not show any abnormalities. Two years later, cervical lymphadenopathy, hepatosplenomegaly and atypical lymphocytes in peripheral blood revealed leukemia. At the same time, acquired ichthyosis was observed. Subsequently, neurological abnormalities revealed myelopathy associated with HTLV-1, due to vertical transmission.
Gonçalves
Denise Utsch
DU
Tropical Medicine Post Graduate Program, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Felipe
Lílian
L
Carneiro-Proietti
Anna Bárbara
AB
Guedes
Antônio Carlos
AC
Martins-Filho
Olindo Assis
OA
Lambertucci
José Roberto
JR
D034381:Hearing Loss / Q000209:etiology*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications* / Q000175:diagnosis; D008297:Male; D015493:Paraparesis, Tropical Spastic / Q000150:complications* / Q000175:diagnosis; D055815:Young Adult