title: Encephalomyelitis mimicking multiple sclerosis associated with chronic graft-versus-host disease after allogeneic bone marrow transplantation.
abstract: We describe a case of encephalomyelitis mimicking multiple sclerosis associated with chronic graft-versus-host disease (GVHD) occurring after allogeneic bone marrow transplantation (BMT) for myelodysplastic syndrome. Immunosuppressive therapy, consisting of a therapeutic dose of cyclosporine A and a maintenance dose of methylprednisolone, was effective in treating symptoms. Although central nervous system GVHD is very rare and remains controversial, presentation of neurological symptoms after allogeneic BMT warrants consideration of GVHD in the differential diagnosis.
authors.affiliation: Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka.
authors.forename: Yayoi
authors.initials: Y
authors.lastname: Matsuo
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kamezaki
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Takeishi
authors.forename: Katsuto
authors.initials: K
authors.lastname: Takenaka
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Eto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nonami
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Hiromi
authors.initials: H
authors.lastname: Iwasaki
authors.forename: Naoki
authors.initials: N
authors.lastname: Harada
authors.forename: Koji
authors.initials: K
authors.lastname: Nagafuji
authors.forename: Takanori
authors.initials: T
authors.lastname: Teshima
authors.forename: Koichi
authors.initials: K
authors.lastname: Akashi
mesh_terms: D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004679:Encephalomyelitis / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000209:etiology; D014184:Transplantation, Homologous / Q000009:adverse effects; D055815:Young Adult