title: Hepatic metastases of gastric adenocarcinoma showing metabolic remission on FDG-PET despite an increase in size on CT.
abstract: We report a gastric adenocarcinoma patient with liver metastases. The metastases showed progression on computed tomography (CT), but this was not true progression in terms of metabolic activity according to (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET). Discordance between size criteria and metabolic criteria has been reported in liver gastrointestinal stromal tumors, hepatomas, and renal cell carcinomas after dramatic responses with targeted therapies such as imatinib, sorafenib, and sunitinib (1-6). However, this discordance has been rarely reported in liver metastases of gastric adenocarcinoma when treated with conventional chemotherapy.
authors.affiliation: Department of Hematooncology, Konkuk University Medical Center, Seoul, Korea. greenteamd@gmail.com
authors.forename: So Young
authors.initials: SY
authors.lastname: Yoon
authors.forename: Sung-Yong
authors.initials: SY
authors.lastname: Kim
authors.forename: Yo-Han
authors.initials: YH
authors.lastname: Cho
authors.forename: Hyun Woo
authors.initials: HW
authors.lastname: Chung
authors.forename: Young
authors.initials: Y
authors.lastname: So
authors.forename: Hong M
authors.initials: HM
authors.lastname: Lee
references.citation: Eur J Nucl Med Mol Imaging. 2005 Feb;32(2):153-62
references.pmid: 15690223
references.citation: J Clin Oncol. 2007 May 1;25(13):1760-4
references.pmid: 17470866
references.citation: J Clin Oncol. 2006 Sep 10;24(26):4293-300
references.pmid: 16908937
references.citation: J Natl Cancer Inst. 2000 Feb 2;92(3):205-16
references.pmid: 10655437
references.citation: J Nucl Med. 2004 Mar;45(3):357-65
references.pmid: 15001674
references.citation: J Clin Oncol. 2006 Dec 10;24(35):5601-8
references.pmid: 17158546
references.citation: J Clin Oncol. 2007 May 1;25(13):1753-9
references.pmid: 17470865
references.citation: Eur J Cancer. 2003 Sep;39(14):2012-20
references.pmid: 12957455