title: Chemical and biological studies of Ribes nigrum L. buds essential oil.
abstract: Ribes nigrum buds are used in medicine for the diuretic and antiseptic properties of their volatile compounds. We present in this paper comparative data concerning the chemical composition of Ribes nigrum buds essential oils obtained from three blackcurrant varieties. Essential oils were isolated by steam distillation and were analyzed by gas chromatography coupled with mass spectrometry. The Ribes nigrum essential oils (extracted from all three varieties) exhibited similar and large antibacterial spectrum, acting against Acinetobacter (A.) baumanii, Escherichia (E.) coli, Pseudomonas (P.) aeruginoasa and Staphylococcus (S.) aureus, as proved by the very low MIC values observed for the respective strains. The subinhibitory concentrations of the essential oils induced a decrease in the bacterial ability to colonize the inert substratum for A. baumanii, E. coli and S. aureus, demonstrating that besides the bactericidal activity, the Ribes nigrum essential oils also exhibit anti-pathogenic potential.
authors.affiliation: University of Bucharest, Faculty of Chemistry, Bucharest, Romania. eliza_oprea2003@yahoo.com
authors.forename: Eliza
authors.initials: E
authors.lastname: Oprea
authors.forename: Valeria
authors.initials: V
authors.lastname: Radulescu
authors.forename: Carmen
authors.initials: C
authors.lastname: Balotescu
authors.forename: Veronica
authors.initials: V
authors.lastname: Lazar
authors.forename: Marcela
authors.initials: M
authors.lastname: Bucur
authors.forename: Paulina
authors.initials: P
authors.lastname: Mladin
authors.forename: Ileana Cornelia
authors.initials: IC
authors.lastname: Farcasanu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D031965:Ribes / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D009822:Oils, Volatile; D010936:Plant Extracts