title: Robust and fast shell registration in PET and MR/CT brain images.
abstract: A robust and fast hybrid method using a shell volume that consists of high contrast voxels with their neighbors is proposed for registering PET and MR/CT brain images. Whereas conventional hybrid methods find the best matched pairs from several manually selected or automatically extracted local regions, our method automatically selects a shell volume in the PET image, and finds the best matched corresponding volume using normalized mutual information (NMI) in overlapping volumes while transforming the shell volume into an MR or CT image. A shell volume not only can reduce irrelevant corresponding voxels between two images during optimization of transformation parameters, but also brings a more robust registration with less computational cost. Experimental results on clinical data sets showed that our method successfully aligned all PET and MR/CT image pairs without losing any diagnostic information, while the conventional registration methods failed in some cases.
authors.affiliation: School of Computer Science and Engineering, Seoul National University, Gwanak-gu, Seoul 151-742, Republic of Korea. holee@cglab.snu.ac.kr
authors.forename: Ho
authors.initials: H
authors.lastname: Lee
authors.forename: Jeongjin
authors.initials: J
authors.lastname: Lee
authors.forename: Namkug
authors.initials: N
authors.lastname: Kim
authors.forename: In Kyoon
authors.initials: IK
authors.lastname: Lyoo
authors.forename: Yeong Gil
authors.initials: YG
authors.lastname: Shin
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed