title: Integrated profile to assess auditory nerve-auditory pathway integrity.
abstract: OBJECTIVE
  To evaluate the Integrated Cochlear Profile for Assessing Auditory Nerve-Auditory Pathway Integrity (ICP-API), as proposed by our group, in the selection of cochlear implant candidates.
  
  
  METHODS
  The API of the candidates for cochlear implantation were assessed with the ICP-API, which consists of 5 categories including: audiological testing; radiological imaging study; ear-canal electric response audiometry; response to environmental sounds; speech development level. The auditory rehabilitation effects of the cochlear implantation receivers were evaluated postoperatively.
  
  
  RESULTS
  Sixty-six of 68 candidates who met the criteria of the ICP-API received cochlear implantation with improved hearing and speech development postoperatively. The remaining 2 of the 68 candidates were diagnosed with bilateral auditory nerves aplasia, and therefore failed cochlear implants were avoided.
  
  
  CONCLUSIONS
  The ICP-API is valuable and feasible for the selection of cochlear implant candidates. The API should be considered as one of the most important criteria for cochlear implant candidate selection.
authors.affiliation: Department of Otorhinolaryngology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. wjkong888@yahoo.com
authors.forename: Wei-Jia
authors.initials: WJ
authors.lastname: Kong
authors.forename: Hua-Mao
authors.initials: HM
authors.lastname: Cheng
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Wang
authors.forename: Su-Lin
authors.initials: SL
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Hui
authors.initials: H
authors.lastname: Ma
authors.forename: Ping
authors.initials: P
authors.lastname: Han
authors.forename: Xiang-Quan
authors.initials: XQ
authors.lastname: Kong
mesh_terms: D000293:Adolescent; D001299:Audiometry; D001306:Auditory Pathways / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003054:Cochlear Implants; D003056:Cochlear Nerve / Q000473:pathology / Q000503:physiopathology; D004424:Ear Canal; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006320:Hearing Tests; D006801:Humans; D007223:Infant; D007804:Language Development; D008279:Magnetic Resonance Imaging; D008297:Male; D018579:Patient Selection; D012189:Retrospective Studies; D013060:Speech; D014057:Tomography, X-Ray Computed