One-pot synthesis of 4-arylquinolines from aromatic aminoketones and vinylphosphonium salts.
The addition of acetylenic esters to aromatic amines such as 2-amino benzophenone derivatives in the presence of triphenylphosphine leads to highly functionalized phosphoranes, which undergo an intramolecular Wittig reaction following oxidation to produce quinoline derivatives.
Asghari
Sakineh
S
Department of Chemistry, Mazandaran University, PO Box 453, Babolsar, Iran. s.asghari@umz.ac.ir
Qandalee
Mohammad
M
Naderi
Zahra
Z
Sobhaninia
Zahra
Z
D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D012492:Salts / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
D000588:Amines; D006841:Hydrocarbons, Aromatic; D007659:Ketones; D011804:Quinolines; D012492:Salts; D014753:Vinyl Compounds
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