Neurosurgery for obsessive-compulsive disorder: contemporary approaches.
Surgery for psychiatric disorders has a controversial history. Traditionally, procedures were undertaken to physically disconnect or destroy certain areas of the brain thought to constitute critical components of the limbic pathways. The relatively recent advent of the much safer and non-destructive technique known as deep brain stimulation has coincided with a resurgence in interest in psychosurgery. Contemporary approaches to the surgical management of obsessive-compulsive disorder are discussed, together with our current understanding of its pathophysiology.
Bear
Renee E
RE
School of Psychology, Deakin University, Burwood, Victoria, Australia.
Fitzgerald
Paul
P
Rosenfeld
Jeffrey V
JV
Bittar
Richard G
RG
D001921:Brain / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery*; D046690:Deep Brain Stimulation / Q000379:methods / Q000639:trends*; D049673:History, 20th Century; D006801:Humans; D009434:Neural Pathways / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery; D009480:Neuropharmacology / Q000266:history / Q000379:methods / Q000639:trends; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D011612:Psychosurgery / Q000009:adverse effects / Q000266:history* / Q000379:methods; D011613:Psychotherapy / Q000266:history / Q000379:methods / Q000639:trends; D018570:Risk Assessment