title: Iridoids and sesquiterpenoids from the roots of Valeriana officinalis.
abstract: Two new iridoids, volvaltrates A and B (1 and 2), and three new sesquiterpenoids, E-(-)-3beta,4beta-epoxyvalerenal (3), E-(-)-3beta,4beta-epoxyvalerenyl acetate (4), and mononorvalerenone (5), together with five known iridoids and two known sesquiterpenoids were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1-5 were elucidated by spectroscopic evidence. Compound 1 was an unusual iridoid with an oxygen bridge connecting C-3 and C-10, forming a cage-like structure, and compound 5 was a mononorsesquiterpenoid.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
authors.forename: Peng-Cheng
authors.initials: PC
authors.lastname: Wang
authors.forename: Jiang-Miao
authors.initials: JM
authors.lastname: Hu
authors.forename: Xin-Hui
authors.initials: XH
authors.lastname: Ran
authors.forename: Zhong-Quan
authors.initials: ZQ
authors.lastname: Chen
authors.forename: He-Zhong
authors.initials: HZ
authors.lastname: Jiang
authors.forename: Yu-Qing
authors.initials: YQ
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: You-Xing
authors.initials: YX
authors.lastname: Zhao
mesh_terms: D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D014632:Valerian / Q000737:chemistry*
chemical_list: D039823:Iridoids; D012717:Sesquiterpenes