Iridoids and sesquiterpenoids from the roots of Valeriana officinalis.
Two new iridoids, volvaltrates A and B (1 and 2), and three new sesquiterpenoids, E-(-)-3beta,4beta-epoxyvalerenal (3), E-(-)-3beta,4beta-epoxyvalerenyl acetate (4), and mononorvalerenone (5), together with five known iridoids and two known sesquiterpenoids were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1-5 were elucidated by spectroscopic evidence. Compound 1 was an unusual iridoid with an oxygen bridge connecting C-3 and C-10, forming a cage-like structure, and compound 5 was a mononorsesquiterpenoid.
Wang
Peng-Cheng
PC
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
Hu
Jiang-Miao
JM
Ran
Xin-Hui
XH
Chen
Zhong-Quan
ZQ
Jiang
He-Zhong
HZ
Liu
Yu-Qing
YQ
Zhou
Jun
J
Zhao
You-Xing
YX
D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D014632:Valerian / Q000737:chemistry*
D039823:Iridoids; D012717:Sesquiterpenes