title: Imaging vasculature and lymphatic flow in mice using quantum dots.
abstract: Quantum dots are ideal probes for fluorescent imaging of vascular and lymphatic tissues. On injection into appropriate sites, red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors. We detail methods for use with commercially available quantum dots and discuss common difficulties.
authors.affiliation: Molecular Biosensor and Imaging Center, Carnegie Mellon University, Pittsburgh, PA, USA.
authors.forename: Byron
authors.initials: B
authors.lastname: Ballou
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Ernst
authors.forename: Susan
authors.initials: S
authors.lastname: Andreko
authors.forename: James A J
authors.initials: JA
authors.lastname: Fitzpatrick
authors.forename: B Christoffer
authors.initials: BC
authors.lastname: Lagerholm
authors.forename: Alan S
authors.initials: AS
authors.lastname: Waggoner
authors.forename: Marcel P
authors.initials: MP
authors.lastname: Bruchez
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000503:physiopathology*; D005453:Fluorescence; D042601:Lymphatic Vessels / Q000503:physiopathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D009374:Neoplasms, Experimental / Q000473:pathology / Q000503:physiopathology; D045663:Quantum Dots; D021701:Sentinel Lymph Node Biopsy