Anesthetic management for cesarean delivery in a parturient with exacerbated hemophagocytic syndrome.
Hemophagocytic syndrome is an uncommon disease characterized by cytokine dysfunction and uncontrolled hemophagocytosis. It arises rarely during pregnancy, in which case maternal and fetal mortality are relatively high. It has some similarities with HELLP syndrome. Poor maternal condition increases the risk of preterm labor and the possibility of emergency cesarean delivery in non-optimal conditions, presenting a great challenge to the anesthesiologists. We report a 28-year-old primigravida with the onset of hemophagocytic syndrome and cyopenia at 23 weeks of gestation. A further exacerbation at 28 weeks of gestation brought on preterm labor. General anesthesia was provided successfully for cesarean delivery. The patient recovered completely after this episode. We suggest that early diagnosis, multi-disciplinary intervention, pre-operative correction of the hematological abnormalities, general anesthesia and close postoperative monitoring are necessary.
Chien
C-T
CT
Department of Anesthesiology, Taichung Verterans General Hospital, No.160, Sec. 3, Chung-Kang Road Rd., Taichung City 40705, Taiwan. carloscat@gmail.com
Lee
F-J
FJ
Luk
H-N
HN
Wu
C-C
CC
D000328:Adult; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D001034:Apgar Score; D002585:Cesarean Section; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications*; D008297:Male; D016343:Monitoring, Intraoperative; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic