title: Changes of blood flow volume in the superior mesenteric artery and brachial artery with abdominal thermal stimulation.
abstract: In traditional Chinese medicine, moxibustion is a local thermal therapy that is used for several conditions. Quantifying the effects of moxibustion therapy has been difficult because the treatment temperature depends on the physician's experience, and the temperature distribution in the target area is not uniform. This prospective observational study aims to quantify the effect of local thermal stimulation to the abdomen. We developed a heat transfer control device (HTCD) for local thermal stimulation. Twenty-four healthy subjects were enrolled and they underwent abdominal thermal stimulation to the para-umbilical region with the device for 20 min. Blood flow volume in the superior mesenteric artery (SMA) and brachial artery (BA), the heart rate and the blood pressure were measured at rest, 15 min after starting thermal stimulation and 10, 20, 30 and 40 min after completing thermal stimulation. Blood flow parameters were measured by high-resolution ultrasound. In the SMA, blood flow volume was significantly increased during thermal stimulation (P < .01), as well as at 10 min (P < .01) and 20 min (P < .05) after stimulation. In the BA, blood flow volume decreased at 40 min after stimulation (P < .01). In conclusion we could quantify the effect of local thermal stimulation with an HTCD and high-resolution ultrasound. Thermal stimulation of the para-umbilical region increased blood flow in the SMA 20 min after stimulation in healthy subjects.
authors.affiliation: Center for Asian Traditional Medicine, Graduate School of Medicine, Tohoku University, Miyagi, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Takayama
authors.forename: Takashi
authors.initials: T
authors.lastname: Seki
authors.forename: Masashi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Shigeru
authors.initials: S
authors.lastname: Takashima
authors.forename: Norihiro
authors.initials: N
authors.lastname: Sugita
authors.forename: Satoshi
authors.initials: S
authors.lastname: Konno
authors.forename: Takashi
authors.initials: T
authors.lastname: Takeda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Arai
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yambe
authors.forename: Nobuo
authors.initials: N
authors.lastname: Yaegashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshizawa
authors.forename: Shigenao
authors.initials: S
authors.lastname: Maruyama
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Nitta
references.citation: Dig Dis Sci. 2008 Mar;53(3):689-93
references.pmid: 17768682
references.citation: Gut. 1987 May;28(5):583-7
references.pmid: 3596339
references.citation: Dig Dis Sci. 2004 Apr;49(4):602-10
references.pmid: 15185864
references.citation: Burns. 2002 Dec;28(8):713-7
references.pmid: 12464468
references.citation: Scand J Gastroenterol. 1993 Jan;28(1):1-9
references.pmid: 8430269
references.citation: Ultrasound Obstet Gynecol. 1996 Aug;8(2):77-81
references.pmid: 8883307
references.citation: Gastroenterology. 1988 Nov;95(5):1294-301
references.pmid: 3049214
references.citation: Evid Based Complement Alternat Med. 2008 Jun;5(2):145-51
references.pmid: 18604254
references.citation: J Cardiol. 2008 Apr;51(2):106-13
references.pmid: 18522783
references.citation: Phys Ther. 1972 Mar;52(3):273-8
references.pmid: 5059320
references.citation: Regul Pept. 2000 Sep 25;93(1-3):93-107
references.pmid: 11033057
references.citation: Best Pract Res Clin Gastroenterol. 2001 Feb;15(1):99-119
references.pmid: 11355903
references.citation: Psychother Psychosom. 2005;74(5):288-94
references.pmid: 16088266
references.citation: J Biomech Eng. 2003 Dec;125(6):832-40
references.pmid: 14986408
references.citation: Dig Dis Sci. 2005 Feb;50(2):366-74
references.pmid: 15745102
references.citation: Scand J Gastroenterol. 2006 Sep;41(9):1056-63
references.pmid: 16938719
references.citation: J Clin Ultrasound. 1994 Mar-Apr;22(3):149-60
references.pmid: 8169234
references.citation: J Clin Ultrasound. 2001 Mar-Apr;29(3):130-9
references.pmid: 11329155
references.citation: Ann Surg. 2007 Aug;246(2):229-35
references.pmid: 17667501
references.citation: Eur J Radiol. 2007 Nov;64(2):202-12
references.pmid: 17923366
references.citation: Phys Med Biol. 2006 Jun 7;51(11):N221-9
references.pmid: 16723759
references.citation: Aliment Pharmacol Ther. 2005 Feb 1;21(3):201-15
references.pmid: 15691294
references.citation: Zhongguo Zhen Jiu. 2008 Jun;28(6):463-7
references.pmid: 18630550
references.citation: Zhongguo Zhen Jiu. 2006 Jun;26(6):454-8
references.pmid: 16813192
references.citation: J Physiol. 2000 Aug 1;526 Pt 3:471-80
references.pmid: 10922000
references.citation: Eur J Vasc Endovasc Surg. 2001 Feb;21(2):106-17
references.pmid: 11237782
references.citation: Clin Radiol. 2001 Dec;56(12):973-8
references.pmid: 11795926
references.citation: Exp Biol Med (Maywood). 2003 Nov;228(10):1245-9
references.pmid: 14610268
references.citation: Am Heart J. 2003 Oct;146(4):728-33
references.pmid: 14564334
references.citation: Circulation. 1995 May 15;91(10):2582-90
references.pmid: 7743620
references.citation: Am J Chin Med. 2007;35(6):947-54
references.pmid: 18186581
references.citation: J Neurol Neurosurg Psychiatry. 1967 Aug;30(4):319-24
references.pmid: 6055340
references.citation: Radiology. 1990 Jan;174(1):165-9
references.pmid: 2403678
references.citation: Abdom Imaging. 1997 Sep-Oct;22(5):483-6
references.pmid: 9233882
references.citation: Acta Physiol Scand. 1986 Nov;128(3):467-70
references.pmid: 3788622
references.citation: Radiol Clin North Am. 1985 Dec;23(4):641-57
references.pmid: 3906753
references.citation: Evid Based Complement Alternat Med. 2009 Mar;6(1):77-83
references.pmid: 18955224
references.citation: Radiology. 1990 Feb;174(2):297-307
references.pmid: 2404309
references.citation: Burns. 2002 Feb;28(1):27-34
references.pmid: 11834326
references.citation: J Appl Physiol. 1948 Aug;1(2):93-122
references.pmid: 18887578
references.citation: Psychosom Med. 2005 Jul-Aug;67(4):643-7
references.pmid: 16046381
references.citation: Digestion. 2004;69(3):131-9
references.pmid: 15114043
references.citation: J Cardiol. 2001;37 Suppl 1:155-9
references.pmid: 11433821
references.citation: Ultrasound Med Biol. 1985 Jul-Aug;11(4):625-41
references.pmid: 2931884
references.citation: J Cardiol. 1994 May-Jun;24(3):175-83
references.pmid: 8207631
references.citation: Am J Physiol Gastrointest Liver Physiol. 2006 Feb;290(2):G285-92
references.pmid: 16254048
references.citation: Clin Sci. 1957 Feb;16(1):67-74
references.pmid: 13414140