title: Cell based vaccination using transplantation of iPSC-derived memory B cells.
abstract: The recently developed induced pluripotent stem cell (iPSC) technique provides new direction for vaccination: somatic cells can be induced into iPSCs and expanded, then the cells are genetically or chemically promoted to a immune cell fate, followed with in vitro antigen presenting and processing processes to produce memory B cells that can secret functional antibodies to different pathogens; finally these cells are transplanted back to human.
authors.forename: Jiang
authors.initials: J
authors.lastname: Li
authors.forename: Guo-Dong
authors.initials: GD
authors.lastname: Gao
authors.forename: Ti-Fei
authors.initials: TF
authors.lastname: Yuan
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology*; D002454:Cell Differentiation; D006801:Humans; D007156:Immunologic Memory; D039904:Pluripotent Stem Cells / Q000276:immunology*; D033581:Stem Cell Transplantation; D014611:Vaccination / Q000379:methods*