Successful management of Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon using vincristine and ticlopidine.
Kaposiform hemangioendothelioma is a rare locally aggressive vascular tumor that usually occurs in skin and retroperitoneum of infants and young children. We present a case of a newborn with a rapid tumor growth and a life-threatening Kasabach-Merritt syndrome with a progressive remission after treatment with vincristine and ticlopidine.
López
Verónica
V
Department of Dermatology, Hospital Clínico Universitario de Valencia, Valencia, Spain. veronical_c@hotmail.com
Martí
Nuria
N
Pereda
Carolina
C
Martín
José María
JM
Ramón
Dolores
D
Mayordomo
Empar
E
Jordá
Esperanza
E
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D001778:Blood Coagulation Disorders / Q000150:complications* / Q000188:drug therapy; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006390:Hemangioendothelioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy*; D013988:Ticlopidine / Q000008:administration & dosage*; D014750:Vincristine / Q000008:administration & dosage*
D000972:Antineoplastic Agents, Phytogenic; D005343:Fibrinolytic Agents; D014750:Vincristine; D013988:Ticlopidine