Interplay among nitric oxide and reactive oxygen species: a complex network determining cell survival or death.
Programmed cell death (PCD) is an integrated cellular process occurring in plant growth, development, and defense responses to facilitate normal growth and development and better survival against various stresses as a whole. As universal toxic chemicals in plant and animal cells, reactive oxygen or nitrogen species (ROS or RNS), mainly superoxide anion (O(2) (-*)), hydrogen peroxide (H(2)O(2)) or nitric oxide ((*)NO), have been studied extensively for their roles in PCD induction. Physiological and genetic studies have convincingly shown their essential roles. However, the details and mechanisms by which ROS and (*)NO interplay and induce PCD are not well understood. Our recent study on Cupressus lusitanica culture cell death revealed the elicitor-induced co-accumulation of ROS and (*)NO and interactions between (*)NO and H(2)O(2) or O(2)-(*) in different ways to regulate cell death. (*)NO and H(2)O(2) reciprocally enhanced the production of each other whereas (*)NO and O(2) (-*) showed reciprocal suppression on each other's production. It was the interaction between (*)NO and O(2)-(*) but not between (*)NO and H(2)O(2) that induced PCD, probably through peroxynitrite (ONOO(-)). In this addendum, some unsolved issues in the study were discussed based on recent studies on the complex network of ROS and (*)NO leading to PCD in animals and plants.
Zhao
Jian
J
J Biol Chem. 2000 Jul 14;275(28):21409-15
10770952
Plant Physiol. 2002 Oct;130(2):698-708
12376637
J Biol Chem. 2007 Jul 20;282(29):21160-8
17491015
Plant Physiol. 2006 Jun;141(2):404-11
16603664
Planta. 2002 Sep;215(5):708-15
12244435
Plant Cell. 2005 Dec;17(12):3436-50
16272429
J Biol Chem. 2004 Jun 4;279(23):24100-7
15056652
Plant Signal Behav. 2006 Mar;1(2):46-51
19521475
Plant Physiol. 2002 Aug;129(4):1642-50
12177477
Science. 1996 Sep 27;273(5283):1853-6
8791589
Science. 2003 Apr 25;300(5619):650-3
12714747
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13454-9
11606758
Nat Cell Biol. 2005 Jul;7(7):645-6
15990893
Mol Plant Microbe Interact. 2004 Mar;17(3):245-53
15000391
J Biol Chem. 2007 Jul 13;282(28):20739-51
17513301
Plant Physiol. 2005 Jul;138(3):1516-26
15980200
Plant J. 2006 Dec;48(5):784-95
17092315
Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L262-8
15246980
J Mol Cell Cardiol. 2003 Apr;35(4):357-66
12689815
Plant Physiol. 2005 Mar;137(3):921-30
15734904
J Biol Chem. 1998 Jun 5;273(23):14085-9
9603906
Ann N Y Acad Sci. 2000;899:209-21
10863541
Plant Physiol. 2000 Feb;122(2):573-82
10677450
Curr Med Chem. 2007;14(24):2597-621
17979713
J Biol Chem. 2000 Apr 14;275(15):10812-8
10753874
Plant Physiol. 2006 May;141(1):208-19
16531480
Planta. 2005 Aug;221(6):757-65
15744494
Biotechnol Bioeng. 2005 Jun 5;90(5):621-31
15834951
Mol Plant Microbe Interact. 2000 Dec;13(12):1380-4
11106031
Plant Physiol. 2006 Jun;141(2):379-83
16760491
Plant J. 2006 Jan;45(1):113-22
16367958
Plant Physiol Biochem. 2005 Sep;43(9):828-35
16289945
Physiol Rev. 2007 Jan;87(1):315-424
17237348
New Phytol. 2005 Jan;165(1):121-30
15720627
Plant Physiol. 2007 Mar;143(3):1282-92
17277089
Biotechnol Adv. 2005 Jun;23(4):283-333
15848039
Plant Physiol. 2005 Mar;137(3):1092-104
15728341
Plant Cell. 2003 Oct;15(10):2320-32
14508004