[Effect of eradication therapy on nitrogen oxide activity in the gastric juice of patients with chronic gastritis and ulcer disease].
Effect of different ofHelicobacter pylori eradication therapy On nitrogen oxide (NO) levels in the gastric juice was evaluated in 105 patients with chronic non-atrophic gastritis (CNAG) and duodenal ulcer (DU). A rise in NO concentration was associated with exacerbation of CNAG and DU. It decreased to the normal value by the end of therapy in CNAG cases but remained above that in patients with DU. The optimum scheme of eradication therapy included combination of omeprazole (proton pump inhibitoir) and two antibiotics (clarithromycin and amoxicillin).
Esedov
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Magomedéminova
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D000328:Adult; D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D017291:Clarithromycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism / Q000382:microbiology; D005756:Gastritis / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000378:metabolism*; D009853:Omeprazole / Q000627:therapeutic use; D054328:Proton Pump Inhibitors
D000900:Anti-Bacterial Agents; D054328:Proton Pump Inhibitors; D009569:Nitric Oxide; D000658:Amoxicillin; D017291:Clarithromycin; D009853:Omeprazole