title: Human papillomavirus infection in Honduran women with normal cytology.
abstract: OBJECTIVE
  This study was aimed at estimating type-specific HPV prevalence and its cofactors among Honduran women with normal cytology in order to provide valuable information to health policymakers about the epidemiology of this important sexually transmitted infection.
  
  
  METHODS
  A total of 591 women with normal cytology from Tegucigalpa, Honduras were interviewed and tested for HPV using the SPF10 LiPA25. A structured epidemiological questionnaire was administered to each woman.
  
  
  RESULTS
  The overall HPV prevalence was 51%. Twenty-three types of HPV were detected; HPV 16, 51, 31, 18, and 11 were the most common. The highest prevalence of cancer associated HPV types (15.0%) was found in the women less than 35 years. Besides the association with age, the main independent predictors of HPV infection were the lifetime number of sexual partners and having a low socioeconomic status and less than 5 previous Pap smears.
  
  
  CONCLUSIONS
  In the population studied, there was a broad diversity of HPV infections, with high-risk types being the most common types detected. The establishment of a well-characterized population with regard to the community prevalence of type-specific HPV infection will provide a valuable baseline for monitoring population effectiveness of an HPV vaccine.
authors.affiliation: Department of Microbiology, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa, Honduras.
authors.forename: N
authors.initials: N
authors.lastname: Tábora
authors.forename: J M J E
authors.initials: JM
authors.lastname: Bakkers
authors.forename: W G V
authors.initials: WG
authors.lastname: Quint
authors.forename: L F A G
authors.initials: LF
authors.lastname: Massuger
authors.forename: J A
authors.initials: JA
authors.lastname: Matute
authors.forename: W J G
authors.initials: WJ
authors.lastname: Melchers
authors.forename: A
authors.initials: A
authors.lastname: Ferrera
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D005260:Female; D006721:Honduras / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D016133:Polymerase Chain Reaction; D011230:Precancerous Conditions / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors
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