Primary cutaneous anaplastic large cell lymphoma of the vulva: a typical cutaneous lesion with an 'atypical' presenting site.
Non-Hodgkin lymphoma of vulva is exceedingly rare and it often poses a diagnostic challenge if their existence is not suspected. We report a patient who has primary cutaneous anaplastic large cell (C-ALCL) with an unusual presentation as a vulvar ulcer. She received a brief course of chemotherapy followed by local irradiation and has remained disease-free more than a year from the time of diagnosis. To our knowledge, primary C-ALCL involving the vulva has never been reported. Despite its typical cutaneous manifestation of C-ALCL, the uncommon presenting site of this entity warrants recognition because of its prognostic and therapeutic implication.
Koh
Liang Piu
LP
Department of Hematology-Oncology, National University Hospital, Singapore, 119074, Singapore. liangpiu@yahoo.com.sg.
Wong
Lea Choung
LC
Department of Radiation Oncology, National University Hospital, Singapore, Singapore.
Ng
Siok Bian
SB
Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Poon
Michelle L M
MLM
Department of Hematology-Oncology, National University Hospital, Singapore, 119074, Singapore.
Low
Jeffrey J H
JJH
Department of Obstetrics and Gynaecology, National University Hospital, Singapore, Singapore.
D000328:Adult; D005260:Female; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D049268:Positron-Emission Tomography; D011379:Prognosis; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D014846:Vulvar Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy
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