[Chemical constituents from air-dried Piper longum].
OBJECTIVE
To study the chemical constituents of Piper longum.


METHODS
The whole plant of air-dried P. longum. was extracted with 95% EtOH. The EtOH extract was suspended in H2O and extracted with petroleum ether, CHC13 and n-BuOH, successively. The compounds were isolated and purified by column chromatography from the CHCl3 fraction, and identified based on spectral analyses (MS,1H-NMR, 13C-NMR).


RESULTS
Threeteen compounds were isolated from P. longum, and were characterized as 1-(3',4'-methylenedioxyphenyl)-1E-tetradecene (1), 3-(3', 4'-methylenedioxophenyl)-propenal (2), piperoic acid (3), 3',4'-di-hydroxy-biabola-1,10-diene (4), eudesm-4(15)-ene-1beta, 6alpha-diol (5), 7-epi- eudesm-4( 15)-ene-1beta, 6beta-diol (6), guineesine (7), piperine (8), pipericide (9), 2E, 4E-dienamide (10), (2E, 4E, 8E) -N-isobutylhenicosa-2,4,8-trienamide (11), piperlonguminine (12), methyl piperate (13),


CONCLUSIONS
Compounds 1-6 were obtained from P. longum for the first time.
Liu
Wenfeng
W
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
Jiang
Zhiyong
Z
Chen
Jijun
J
Zhang
Xuemei
X
Ma
Yunbao
Y
D000388:Air; D003890:Desiccation; D009930:Organic Chemicals / Q000032:analysis / Q000302:isolation & purification; D031701:Piper / Q000737:chemistry*
D009930:Organic Chemicals