[Acute transverse myelopathy after intramuscular injection of benzathine-benzylpenicillin. Case report in Dakar, Senegal].
Intramuscular injection of benzathine-benzylpenicillin can cause acute transverse myelopathy. The purpose of this report is to describe a case of acute transverse myelopathy observed after injection of benzathine-benzylpenicillin in a 38-year-old man. The patient who was married and had a history of eczema was admitted to the Department of Neurology of the Fann University Teaching Hospital in 2006. All laboratory findings were normal except high serum immunoglobulin E level. An immunoallergic reaction involving inflammatory transverse myelopathy secondary to vasculitis was proposed as the most likely underlying mechanism. Treatment with corticosteroid and physiotherapy led to a favorable outcome. Health personnel should know the indications for use of benzathine-benzylpenicillin and be aware of the possible medullary complications.
Toure
K
K
Mapoure
N Y
NY
Diagne
N G
NG
Faustin
Y N
YN
Diop
M S
MS
Seck
L B
LB
Ndiaye
M
M
Sene Diouf
F
F
Thiam
A
A
Diop
A G
AG
Diagne
M
M
Diaa
Tal
T
Ndiaye
M M
MM
D000328:Adult; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008297:Male; D009187:Myelitis / Q000209:etiology*; D010401:Penicillin G Benzathine / Q000008:administration & dosage* / Q000009:adverse effects* / Q000276:immunology; D012675:Senegal; D014657:Vasculitis / Q000150:complications / Q000276:immunology
D010401:Penicillin G Benzathine