title: A Chryseobacterium meningosepticum colonization outbreak in a neonatal intensive care unit.
abstract: OBJECTIVE
  To report the epidemiologic, bacteriologic, and clinical features of a Chryseobacterium meningosepticum outbreak in a neonatal intensive care unit (NICU) of a referral teaching hospital.
  
  
  METHODS
  From April to October 2002, a strain of C. meningosepticum was isolated from four neonates in the NICU. All neonates were colonized in the endotracheal tubes and respiratory secretions, but none of them progressed to clinical infection. Multiple samples were obtained for cultures.
  
  
  RESULTS
  Pulsed-field gel electrophoresis (PFGE) of isolates showed them to be representatives of a single strain. Environmental surveillance did not reveal the C. meningosepticum source. None of the neonates received specific treatment. The outbreak was only controlled by reinforcement of the usual measures and no additional colonization/infection was confirmed for more than a year after the last case.
  
  
  CONCLUSIONS
  This study suggests that C. meningosepticum colonization in neonates does not necessarily lead to infection and that such colonization outbreaks may be controlled with emphasis on the standard precautions.
authors.affiliation: Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, P.O. Box 1352, 71110 Heraklion, Crete, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Maraki
authors.forename: E
authors.initials: E
authors.lastname: Scoulica
authors.forename: A
authors.initials: A
authors.lastname: Manoura
authors.forename: N
authors.initials: N
authors.lastname: Papageorgiou
authors.forename: C
authors.initials: C
authors.lastname: Giannakopoulou
authors.forename: E
authors.initials: E
authors.lastname: Galanakis
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D012634:Bodily Secretions / Q000382:microbiology; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D045247:Chryseobacterium / Q000302:isolation & purification*; D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D016172:DNA Fingerprinting; D016521:Electrophoresis, Gel, Pulsed-Field; D004783:Environmental Microbiology; D005260:Female; D045826:Flavobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D005838:Genotype; D006115:Greece; D006784:Hospitals, Teaching; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D008826:Microbial Sensitivity Tests; D012137:Respiratory System / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents
references.citation: J Clin Microbiol. 1977 Nov;6(5):450-55
references.pmid: 925147
references.citation: J Clin Pathol. 1981 Apr;34(4):429-33
references.pmid: 7240432
references.citation: J Microbiol Immunol Infect. 2008 Apr;41(2):137-44
references.pmid: 18473101
references.citation: New Microbiol. 2003 Jan;26(1):57-63
references.pmid: 12578312
references.citation: Scand J Infect Dis. 2004;36(6-7):539-40
references.pmid: 15307598
references.citation: Syst Appl Microbiol. 2003 Nov;26(4):523-8
references.pmid: 14666980
references.citation: J Hosp Infect. 2001 Mar;47(3):188-92
references.pmid: 11247678
references.citation: Thorax. 2002 Dec;57(12):1015-20
references.pmid: 12454294
references.citation: J Clin Microbiol. 2004 Jul;42(7):3353-5
references.pmid: 15243115
references.citation: Acta Paediatr Scand. 1989 Jan;78(1):51-5
references.pmid: 2919524
references.citation: Scand J Infect Dis. 2003;35(11-12):882-3
references.pmid: 14723368
references.citation: Clin Exp Ophthalmol. 2004 Aug;32(4):445-7
references.pmid: 15281988
references.citation: Medicine (Baltimore). 1997 Jan;76(1):30-41
references.pmid: 9064486
references.citation: Eur J Clin Microbiol Infect Dis. 1989 Jun;8(6):509-14
references.pmid: 2504590
references.citation: J Microbiol Immunol Infect. 2004 Feb;37(1):35-8
references.pmid: 15060685
references.citation: Infect Control Hosp Epidemiol. 2003 Aug;24(8):613-7
references.pmid: 12940584
references.citation: J Clin Microbiol. 2004 Jan;42(1):445-8
references.pmid: 14715802
references.citation: Am J Infect Control. 2008 Aug;36(6):453-7
references.pmid: 18675153
references.citation: South Med J. 2004 Jan;97(1):74-6
references.pmid: 14746428