title: Light control of peroxisome proliferation during Arabidopsis photomorphogenesis.
abstract: Peroxisomes are multifunctional organelles whose abundance and metabolic activities differ depending on the species, cell type, developmental stage and prevailing environmental conditions.1 However, little is known about the signaling pathways that control these variations, especially in plants. Our laboratory recently investigated the regulatory role of light in changes in peroxisome abundance and identified a phytochrome A-dependent pathway responsible for the proliferation of peroxisomes during dark-to-light transition in Arabidopsis seedlings. Light induces peroxisome proliferation at least in part through upregulating the PEX11b gene, which encodes a peroxisomal membrane protein that mediates the early stages of peroxisome multiplication. Activation of PEX11b requires the far-red light receptor phyA, as well as the bZIP transcription factor HYH, which binds directly to the promoter of PEX11b. We conclude that during photomorphogenesis, both the import of leaf-peroxisome enzymes from the cytosol and the induction of peroxisome proliferation take place to prepare seedlings for photosynthesis and photorespiration. In addition to light, other plant peroxisome proliferators may also exert their functions by targeting members of the PEX11 gene family for transcriptional activation.
authors.affiliation: Department of Energy Plant Research Laboratory; Michigan State University; East Lansing, Michigan USA.
authors.forename: Jianping
authors.initials: J
authors.lastname: Hu
authors.forename: Mintu
authors.initials: M
authors.lastname: Desai
references.citation: Annu Rev Genet. 2004;38:87-117
references.pmid: 15568973
references.citation: Biochim Biophys Acta. 2006 Dec;1763(12):1478-95
references.pmid: 17030442
references.citation: Plant J. 2004 May;38(3):487-98
references.pmid: 15086806
references.citation: Plant Physiol. 2008 Mar;146(3):1117-27
references.pmid: 18203870
references.citation: Annu Rev Cell Dev Biol. 2001;17:701-52
references.pmid: 11687502
references.citation: Nat Rev Genet. 2007 Mar;8(3):217-30
references.pmid: 17304247
references.citation: Planta. 2006 Aug;224(3):569-81
references.pmid: 16738865
references.citation: Plant Cell. 2007 Jan;19(1):333-50
references.pmid: 17220199
references.citation: J Cell Biol. 1995 Apr;129(2):345-55
references.pmid: 7721939
references.citation: Arch Biochem Biophys. 1991 May 15;287(1):68-74
references.pmid: 1897996
references.citation: J Cell Biol. 1995 Feb;128(4):509-23
references.pmid: 7860627
references.citation: Mol Cell Biol. 2002 Dec;22(23):8226-40
references.pmid: 12417726
references.citation: Plant Cell Environ. 2008 Apr;31(4):492-505
references.pmid: 18194426
references.citation: FEBS J. 2005 Oct;272(20):5169-81
references.pmid: 16218949
references.citation: New Phytol. 2004 Mar;161(3):791-799
references.pmid: 33873720
references.citation: Trends Plant Sci. 2003 Apr;8(4):172-8
references.pmid: 12711229
references.citation: J Cell Sci. 2006 May 1;119(Pt 9):1961-72
references.pmid: 16636080