The AGC Kinase MtIRE: A Link to Phospholipid Signaling During Nodulation?
The development of nitrogen fixing root nodules is complex and involves an interplay of signaling processes. During maturation of plant host cells and their endocytosed rhizobia in symbiosomes, host cells and symbiosomes expand. This expansion is accompanied by a large quantity of membrane biogenesis. We recently characterized an AGC kinase gene, MtIRE, that could play a role in this expansion. MtIRE's expression coincides with host cell and symbiosome expansion in the proximal side of the invasion zone in developing Medicago truncatula nodules. MtIRE's closest homolog is the Arabidopsis AGC kinase family IRE gene, which regulates root hair elongation. AGC kinases are regulated by phospholipid signaling in animals and fungi as well as in the several instances where they have been studied in plants. Here we suggest that a phospholipid signaling pathway may also activate MtIRE activity and propose possible upstream activators of MtIRE protein's presumed AGC kinase activity.
Pislariu
Catalina I
CI
Department of Biological Sciences; University of North Texas; Denton, Texas USA.
Dickstein
Rebecca
R
Plant Physiol. 2002 Apr;128(4):1390-401
11950987
Plant Cell. 2003 Sep;15(9):2093-105
12953113
J Exp Bot. 2004 Apr;55(398):957-9
15020639
Plant Physiol. 2004 Nov;136(3):3582-93
15489277
Plant Physiol Biochem. 2006 Feb-Mar;44(2-3):132-42
16647267
EMBO J. 2006 Jan 11;25(1):255-65
16362044
EMBO J. 2004 Feb 11;23(3):572-81
14749726
Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9617-21
7937816
Plant J. 2001 Jan;25(1):55-65
11169182
Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6404-9
16601102
Plant J. 2002 May;30(3):289-99
12000677
Mol Plant Pathol. 2006 May 1;7(3):197-207
20507440
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4701-5
15070781
Science. 2004 Feb 27;303(5662):1361-4
14963335
Plant Physiol. 2003 May;132(1):311-7
12746536
J Biol Chem. 2006 Nov 17;281(46):35520-30
16973627
FEBS Lett. 1999 May 28;451(3):220-6
10371193
Trends Plant Sci. 2003 Sep;8(9):424-31
13678909
Semin Cell Dev Biol. 2004 Apr;15(2):161-70
15209375
Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10375-80
16006515
Plant Physiol. 2007 Jun;144(2):682-94
17237187
Annu Rev Plant Biol. 2003;54:265-306
14502992
J Bacteriol. 1990 Aug;172(8):4295-306
2376562
Plant Cell. 1995 Jul;7(7):869-885
12242391
Mol Plant Microbe Interact. 2005 Aug;18(8):869-76
16134899