Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.
Forconi
Marcello
M
Department of Biochemistry, Beckman Center, B400, Stanford University, Stanford, CA 94305-5307, USA.
Sengupta
Raghuvir N
RN
Liu
Mao-Chin
MC
Sartorelli
Alan C
AC
Piccirilli
Joseph A
JA
Herschlag
Daniel
D
D000818:Animals; D020627:Azoarcus / Q000235:genetics*; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D018360:Crystallography, X-Ray; D006151:Guanosine / Q000737:chemistry / Q000378:metabolism*; D006860:Hydrogen Bonding; D007438:Introns; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D016337:RNA, Catalytic / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013768:Tetrahymena / Q000201:enzymology*
C116167:GIR1 ribozyme; D016337:RNA, Catalytic; D006151:Guanosine
Science. 2005 Sep 2;309(5740):1587-90
16141079
Biochemistry. 1995 Mar 28;34(12):4056-67
7696271
Biochemistry. 2001 May 1;40(17):5161-71
11318638
Curr Opin Chem Biol. 2005 Dec;9(6):585-93
16242990
Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12299-304
10535916
Biochemistry. 2008 Jul 22;47(29):7684-94
18572927
Nature. 1984 Apr 26-May 2;308(5962):820-6
6562377
Biochemistry. 1993 May 18;32(19):5247-56
8494902
RNA. 1998 May;4(5):498-519
9582093
Biochemistry. 1991 Nov 5;30(44):10632-40
1931984
Science. 1986 Jan 31;231(4737):470-5
3941911
RNA. 1999 Feb;5(2):158-66
10024168
Biochemistry. 1992 Feb 11;31(5):1386-99
1736996
Nature. 2004 Jul 1;430(6995):45-50
15175762
Nucleic Acids Res. 1997 Feb 1;25(3):648-53
9016608
Nat Struct Mol Biol. 2005 Jan;12(1):82-9
15580277
Biochemistry. 1990 Nov 6;29(44):10159-71
2271645
Biochemistry. 1999 Aug 24;38(34):10958-75
10460151
Mol Cell. 2004 Nov 5;16(3):351-62
15525509
J Mol Biol. 1990 Aug 5;214(3):613-7
2388258
Nature. 1989 Nov 23;342(6248):391-5
2685606
J Mol Biol. 2000 Sep 15;302(2):339-58
10970738
Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5699-704
18408159