title: Bilateral haemorrhagic infarction of the globus pallidus after cocaine and alcohol intoxication.
abstract: Cocaine is a risk factor for both ischemic and haemorrhagic stroke. We present the case of a 31-year-old man with bilateral ischemia of the globus pallidus after excessive alcohol and intranasal cocaine use. Drug-related globus pallidus infarctions are most often associated with heroin. Bilateral basal ganglia infarcts after the use of cocaine, without concurrent heroin use, have never been reported. In our patient, transient cardiac arrhythmia or respiratory dysfunction related to cocaine and/or ethanol use were the most likely causes of cerebral hypoperfusion.
authors.affiliation: Department of Neurology, CHU Nîmes, Hôpital Caremeau, Nîmes Cedex 4, France. dimitrirenard@hotmail.com
authors.forename: Dimitri
authors.initials: D
authors.lastname: Renard
authors.forename: Hervé
authors.initials: H
authors.lastname: Brunel
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gaillard
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000150:complications / Q000473:pathology*; D020520:Brain Infarction / Q000209:etiology*; D019970:Cocaine-Related Disorders / Q000150:complications*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005917:Globus Pallidus / Q000473:pathology*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000150:complications* / Q000209:etiology*; D008297:Male