title: Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.
authors.affiliation: Department of Biochemistry, Beckman Center, B400, Stanford University, Stanford, CA 94305-5307, USA.
authors.forename: Marcello
authors.initials: M
authors.lastname: Forconi
authors.forename: Raghuvir N
authors.initials: RN
authors.lastname: Sengupta
authors.forename: Mao-Chin
authors.initials: MC
authors.lastname: Liu
authors.forename: Alan C
authors.initials: AC
authors.lastname: Sartorelli
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Piccirilli
authors.forename: Daniel
authors.initials: D
authors.lastname: Herschlag
mesh_terms: D000818:Animals; D020627:Azoarcus / Q000235:genetics*; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D018360:Crystallography, X-Ray; D006151:Guanosine / Q000737:chemistry / Q000378:metabolism*; D006860:Hydrogen Bonding; D007438:Introns; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D016337:RNA, Catalytic / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013768:Tetrahymena / Q000201:enzymology*
chemical_list: C116167:GIR1 ribozyme; D016337:RNA, Catalytic; D006151:Guanosine
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