title: Reductive and brominative termination of alkenol cyclization in aerobic cobalt-catalyzed reactions.
abstract: Tetrahydrofur-2-ylmethyl radicals were stereoselectively generated from substituted pent-4-en-1-ols in aerobic cobalt(II)-catalyzed oxidations. Intermediates were trapped with cyclohexa-1,4-diene, gamma-terpinene, BrCCl(3), diethyl dibromomalonate, or electron-deficient olefins such as acrylonitrile or dimethyl fumarate to afford functionalized tetrahydrofurans in synthetically useful yields.
authors.affiliation: Fachbereich Chemie, Organische Chemie, Technische Universität Kaiserslautern, D-67663 Kaiserslautern, Germany.
authors.forename: Dominik
authors.initials: D
authors.lastname: Schuch
authors.forename: Patrick
authors.initials: P
authors.lastname: Fries
authors.forename: Maike
authors.initials: M
authors.lastname: Dönges
authors.forename: Bárbara
authors.initials: B
authors.lastname: Menéndez Pérez
authors.forename: Jens
authors.initials: J
authors.lastname: Hartung