Ricinodendron heutelotii (Bail.) or Tetracarpidium conophorum Müll. oils fed to male rats lower blood lipids.
Ricinodendron heudelotii and Tetracarpidium conophorum (Euphorbiaceae family) are 2 oil-bearing wild plants whose fruits are generally consumed in Cameroon. T conophorum kernels are eaten as nibbles after cooking. Kernels of R heudelotii are used as spice in many dishes in Cameroon. Oil from T conophorum contains a high level of alpha-linolenic acid (72.24%), and oil from R heudelotii kernels is a good source of alpha-eleostearic acid (9c, 11t, 13t; 52.61%), which is a conjugated linolenic acid. Polyunsaturated fatty acids have received considerable interest because their consumption has been associated with beneficial health effects. We hypothesized that the consumption of R heudelotii and T conophorum oils would alter the in vivo lipid profiles and some antioxidants parameters. Therefore, male Sprague-Dawley rats (age, 1 month, n = 18) were fed with a standard, commercial diet (control group), or a diet containing T conophorum oil (TCO group) or R heudelotii oil (RHO group). After 60 days of feeding the respective diets, blood samples were collected and used to determine biochemical parameters. High-protein lipoprotein cholesterol, creatinine, alanine aminotransferase, alkaline phosphatase, total bilirubin, malondialdehyde, and selenium levels were not significantly different (P > .05) between the RHO and TCO groups. The atherogenicity index was higher for the group of rats fed a standard, commercial diet compared with the RHO and TCO groups. The oils examined in this study reduced cholesterol and triglyceride levels in rats compared with the control group fed the standard diet.
Leudeu
Bertille Carine Tchankou
BC
Laboratory of Food Technology and Biochemistry, National Advanced School of Agro-Industrial Sciences (ENSAI), Ngaoundere, Cameroon. tchankouleudeu@yahoo.fr
Tchiégang
Clergé
C
Barbé
Françoise
F
Nicolas
Benedicte
B
Guéant
Jean-Louis
JL
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D050197:Atherosclerosis / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D019665:Euphorbiaceae / Q000737:chemistry*; D008055:Lipids / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D010938:Plant Oils / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds; D014280:Triglycerides / Q000097:blood
D008078:Cholesterol, LDL; D004042:Dietary Fats, Unsaturated; D008055:Lipids; D010938:Plant Oils; D014280:Triglycerides; D008315:Malondialdehyde; D002784:Cholesterol; D000469:Alkaline Phosphatase