Cadaveric allograft for wound closure after resection of squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa: a report of 32 resections and repairs in 2 patients.
This is a review of the management of squamous cell carcinoma in 2 adult patients with recessive dystrophic epidermolysis bullosa. The 2 have undergone 32 excisions of squamous cell carcinoma of the skin and soft tissue with subsequent reconstruction. Multiple strategies for wound closure have been described in this population. We highlight the usefulness of full thickness cadaveric allograft alone, to close wounds in situations when primary closure or donor site availability of autograft is limited or suboptimal.
Buonocore
Samuel D
SD
Section of Plastic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT 06520, USA. samuel.buonocore@yale.edu
Ariyan
Stephan
S
D034861:Abdominal Wall; D000328:Adult; D002102:Cadaver; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012086:Reoperation; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods*; D013524:Surgical Flaps; D020858:Tissue and Organ Harvesting / Q000379:methods; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology