title: Ophthalmic complications including retinal detachment in hyperimmunoglobulinemia E (Job's) syndrome: Case report and review of literature.
abstract: Hyperimmunoglobulinemia E (Job's) syndrome is characterized by markedly increased levels of immunoglobulin E, recurrent cutaneous and systemic pyogenic infections, atopic dermatitis, and peripheral eosinophilia. Although ocular involvement in Job's syndrome is rare, there are reports of keratoconus, staphylococcal chalazia with blepharitis, and endophthalmitis by various authors. We present the first case report of retinal detachment with complicated cataract in Job's syndrome.
authors.affiliation: Orbit, Oculoplasty and Oncology Clinic, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India.
authors.forename: Vipul
authors.initials: V
authors.lastname: Arora
authors.forename: Usha R
authors.initials: UR
authors.lastname: Kim
authors.forename: Hadi M
authors.initials: HM
authors.lastname: Khazei
authors.forename: Shivayogi
authors.initials: S
authors.lastname: Kusagur
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007589:Job Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D008297:Male; D012160:Retina / Q000000981:diagnostic imaging / Q000473:pathology; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D014463:Ultrasonography
chemical_list: D007073:Immunoglobulin E
references.citation: Am J Ophthalmol. 2004 Dec;138(6):1057-8
references.pmid: 15629308
references.citation: Cornea. 2004 Jan;23(1):93-6
references.pmid: 14701966
references.citation: Klin Monbl Augenheilkd. 1990 Nov;197(5):432-5
references.pmid: 2290301
references.citation: J Pediatr Ophthalmol Strabismus. 2001 Sep-Oct;38(5):313-4
references.pmid: 11587182
references.citation: Am J Med. 1975 Apr;58(4):553-8
references.pmid: 47711
references.citation: Lancet. 1966 May 7;1(7445):1013-5
references.pmid: 4161105
references.citation: Arch Ophthalmol. 1996 May;114(5):617-18
references.pmid: 8619778