title: The rabbit as an animal model for experimental surgery.
abstract: The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.
authors.affiliation: Cell Therapy Center, University Hospital Antonio Pedro, Fluminense Federal University, Niteroi, RJ, Brazil. monicacalasans@terra.com.br
authors.forename: Mônica Diuana
authors.initials: MD
authors.lastname: Calasans-Maia
authors.forename: Maria Lucia
authors.initials: ML
authors.lastname: Monteiro
authors.forename: Fábio Oliveira
authors.initials: FO
authors.lastname: Ascoli
authors.forename: José Mauro
authors.initials: JM
authors.lastname: Granjeiro
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D011817:Rabbits; D013514:Surgical Procedures, Operative