E2F and retinoblastoma related proteins may regulate GL1 expression in developing Arabidopsis trichomes.
This is an addendum to our recent paper published in The Plant Journal (52:352-61). The major findings were: (1) trichomes on the leaves of gl3-sst sim double mutants developed as large multi-cellular clusters whereas wild type trichomes are composed of single cells; (2) ectopic CYCD3;1 expression in gl3-sst trichomes also resulted in trichome cluster formation; and (3) that GL1 expression is prolonged in the gl3-sst sim trichome clusters. This addendum shows that ectopic CYCD3;1 expression in gl3-sst also enhanced GL1 expression. An analysis of the GL1 promoter found two overlapping potential E2F binding sites in a region of the promoter known to be essential for GL1 function. This finding indicates that GL1 may be directly regulated by the activity of a CYCD3/CDKA complex that phosphorylates E2F-RB bound to the GL1 promoter.
Wenger
Jonathan P
JP
Department of Plant Biology; University of Minnesota; St. Paul, Minnesota USA.
Marks
M David
MD
Cell. 1991 Nov 1;67(3):483-93
1934056
Development. 2003 Oct;130(20):4859-69
12917293
Cell. 1994 Feb 11;76(3):555-66
8313475
Plant Cell. 1993 Dec;5(12):1739-1748
12271054
Plant Physiol. 2007 May;144(1):105-20
17351056
Int J Dev Biol. 2005;49(5-6):579-84
16096966
Plant Cell. 1999 Jul;11(7):1337-50
10402433
Development. 2000 Sep;127(18):3931-40
10952891
Curr Opin Plant Biol. 2003 Feb;6(1):74-8
12495754
Philos Trans R Soc Lond B Biol Sci. 2002 Jun 29;357(1422):823-6
12079678
Annu Rev Genet. 2006;40:77-105
17094738
Trends Plant Sci. 2000 May;5(5):214-9
10785667
Plant Cell. 2002 Aug;14(8):1847-57
12172026
Plant Physiol. 2005 Sep;139(1):316-28
16126853
Plant Cell. 2006 Nov;18(11):3145-57
17098811
EMBO J. 2002 Oct 1;21(19):5036-46
12356720
Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6410-5
11983922
Development. 1998 Apr;125(7):1161-71
9477315
Genetics. 2000 Nov;156(3):1349-62
11063707
Trends Plant Sci. 2002 Nov;7(11):505-11
12417151
Development. 2003 Dec;130(24):5885-94
14561633
Plant J. 2004 Dec;40(6):860-9
15584952
Plant J. 1999 May;18(3):243-52
10377991
Plant J. 2007 Oct;52(2):352-61
17764505