Similar ongoing pregnancy rates after blastocyst transfer in fresh donor cycles and autologous cycles using cryopreserved bipronuclear oocytes suggest similar viability of transferred blastocysts.
This retrospective cohort study compared blastocyst transfers in 136 fresh oocyte donor cycles and 69 autologous cycles using blastocysts derived from culture of thawed bipronuclear oocytes, all with oocytes derived from patients or donors less than 35 years old. The autologous cycles and oocyte donor cycles had similar rates of implantation (65.9% vs. 62.1%, respectively) and ongoing pregnancy (79.7% vs. 75.0%, respectively), suggesting that autologous blastocysts transferred after post-thaw extended culture have viability and implantation potential that are comparable with those of blastocysts transferred in fresh oocyte donor cycles.
Shapiro
Bruce S
BS
Fertility Center of Las Vegas, University of Nevada School of Medicine, Las Vegas, Nevada 89117, USA. bsshapiro@aol.com
Daneshmand
Said T
ST
Garner
Forest C
FC
Aguirre
Martha
M
Hudson
Cynthia
C
Thomas
Shyni
S
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D015925:Cryopreservation; D046149:Embryo Culture Techniques; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000009:adverse effects; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D050498:Live Birth; D018587:Oocyte Donation; D009865:Oocytes; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome