title: [Management of antibiotics-associated diarrhea].
abstract: Antibiotics-associated diarrhea (AAD) is defined as unexplained diarrhea that occurs with the administration of antibiotics. Approximately 20% AAD cases are due to Clostridium difficile. Over the last decade, the incidence of Clostridium difficile-associated disease (CDAD) has progressively increased, and now a significant clinical problem. Recent change in the epidemiology of CDAD and the emergence of an epidemic hypervirulent strain suggest the need for greater attention for infection control, early diagnosis, and more effective treatment modality. However, since most cases of CDAD are both iatrogenic and nosocomial, careful selection of antibiotics, combined with proper hand hygiene and precaution by medical staffs are required.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Hye Sun
authors.initials: HS
authors.lastname: Park
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Han
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016360:Clostridioides difficile; D003967:Diarrhea / Q000209:etiology*; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007167:Immunotherapy; D012008:Recurrence
chemical_list: D000900:Anti-Bacterial Agents