Diffusion-weighted imaging and ADC mapping of head-and-neck paragangliomas: initial experience.
BACKGROUND
Paragangliomas are rare, hypervascularized benign tumors. In some cases a clear differentiation of paragangliomas and other entities is impossible.


METHODS
The authors evaluated ten patients with skull base lesions (paraganglioma n = 7, meningioma n = 1, giant cell tumor n = 1, and neurinoma n = 1) in addition to conventional magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), and calculation of apparent diffusion coefficient (ADC).


RESULTS
Mean ADC values +/- standard deviation of the paragangliomas were 1.304 +/- 0.257 x 10(-3) mm(2)/s and differed from ADC values of the other jugular fossa tumors with 0.743 +/- 0.108 x 10(-3) mm(2)/s and measurement derived from the cerebellum with 0.802 +/- 0.075 x 10(-3) mm(2)/s.


CONCLUSIONS
Due to the difference of ADC values, the authors propose that DWI and ADC mapping could be a promising tool in the diagnostic work-up of paragangliomas.
Aschenbach
René
R
Department of Diagnostic and Interventional Radiology and Neuroradiology, HELIOS Klinikum Erfurt GmbH, Erfurt, Germany. rene.aschenbach@helios-kliniken.de
Basche
Steffen
S
Vogl
Thomas Josef
TJ
Klisch
Joachim
J
D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D010235:Paraganglioma / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019292:Skull Base Neoplasms / Q000175:diagnosis*
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