Some facts about sleep relevant for Landau-Kleffner syndrome.
Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau-Kleffner syndrome (LKS), a thorough characterization of commonalities and differences between the neural correlates of LKS paroxysms and normal sleep oscillations might provide useful information on the neural underpinning of this disorder. Especially, given the suspected role of sleep in brain plasticity, this type of information is needed to assess the link between cognitive deterioration and electroencephalography (EEG) paroxysms during sleep.
Mascetti
Laura
L
Cyclotron Research Centre, University of Liège-Sart Tilman, Liège, Belgium. pmaquet@ulg.ac.be
Foret
Ariane
A
Bonjean
Maxime
M
Matarazzo
Luca
L
Dang-Vu
Thanh
T
Maquet
Pierre
P
D000328:Adult; D001921:Brain / Q000503:physiopathology*; D003072:Cognition Disorders; D004569:Electroencephalography / Q000706:statistics & numerical data*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D009473:Neuronal Plasticity / Q000502:physiology; D017286:Polysomnography; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology