A peculiar phase transition of plasmalogen bilayer membrane under high pressure.
The bilayer phase transition of plasmalogen, monounsaturated plasmenylcholine 1-O-1'-(Z)-octadecenyl-2-oleoyl-sn-glycero-3-phosphocholine (Plg-SOPC), was examined by differential scanning calorimetry, high-pressure transmittance, and fluorescence techniques. The bilayer properties of Plg-SOPC such as the temperature-pressure phase diagram, the thermodynamic quantities of the transition, and the location of a fluorescent membrane probe in the bilayer, were compared with those of a similar phospholipid 1-stearoyl-2-oleoyl-phosphatidylcholine (SOPC). It turned out that a vinyl-ether bond in the sn-1 position of the glycerol backbone in the Plg-SOPC molecule produces a peculiar phase transition under high pressure and significantly affects the membrane properties.
Broniec
Agnieszka
A
Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Goto
Masaki
M
Matsuki
Hitoshi
H
D002462:Cell Membrane / Q000737:chemistry*; D008027:Light; D008051:Lipid Bilayers / Q000737:chemistry*; D044367:Phase Transition; D010713:Phosphatidylcholines / Q000737:chemistry; D010955:Plasmalogens / Q000737:chemistry*; D011312:Pressure; D012542:Scattering, Radiation; D013696:Temperature
D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D010955:Plasmalogens; C027891:1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine