title: Sulpiride adjunction to clozapine in treatment-resistant schizophrenic patients: a preliminary case series study.
abstract: Six chronic neuroleptic-resistant schizophrenic patients, partial responders to clozapine, were co-administered 600 mg/day of sulpiride (a selective D(2) dopaminergic antagonist) as an augmentation to clozapine (a relatively weak D(2) blocker), for 10 weeks, open-labeled. A remarkable reduction in positive and negative symptoms was observed in four of the six patients.
authors.forename: R
authors.initials: R
authors.lastname: Shiloh
authors.forename: Z
authors.initials: Z
authors.lastname: Zemishlany
authors.forename: D
authors.initials: D
authors.lastname: Aizenberg
authors.forename: A
authors.initials: A
authors.lastname: Weizman