title: Disseminated varicella zoster virus in an immunized child as the acquired immunodeficiency syndrome-defining illness.
abstract: Varicella zoster virus (VZV) immunization aids in the prevention of future VZV infections in immunocompetent patients; however, severely immunocompromised patients remain at increased risk of VZV infection. We report a case of a 10-year-old boy previously immunized to Varicella who presented with herpes zoster with hematogenous dissemination as the Acquired Immunodeficiency Syndrome-defining illness. Disseminated VZV is more commonly seen in human immunodeficiency virus (HIV)-infected individuals with more advanced disease, as was the case with our patient. Disseminated VZV infection in a previously immunized child should raise suspicion for underlying immunosuppression.
authors.affiliation: Department of Medicine, Cuyahoga Falls General Hospital, Cuyahoga Falls, Ohio, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Chilek
authors.forename: Shannon
authors.initials: S
authors.lastname: Routhouska
authors.forename: Joan
authors.initials: J
authors.lastname: Tamburro
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000635:transmission; D002648:Child; D006562:Herpes Zoster / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D053061:Herpes Zoster Vaccine / Q000008:administration & dosage / Q000276:immunology; D014645:Herpesvirus 3, Human; D006801:Humans; D016867:Immunocompromised Host; D018445:Infectious Disease Transmission, Vertical; D008297:Male
chemical_list: D053061:Herpes Zoster Vaccine