Nephrotoxicity associated with the use of intravenous colistin.
We retrospectively assessed the renal toxicity associated with the use of intravenous colistin. Fifty-four patients with multidrug-resistant Acinetobacter infections were included. At the end of therapy 6/54 patients (11%) suffered renal impairment. Renal impairment associated with the use of colistin is less frequent than initially reported.
Santamaría
Cecilia
C
Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Division of Infectious Diseases, Buenos Aires, Argentina. chusantamaria@gmail.com
Mykietiuk
Analia
A
Temporiti
Elena
E
Stryjewski
Martin E
ME
Herrera
Fabian
F
Bonvehi
Pablo
P
D000151:Acinetobacter Infections / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D003091:Colistin / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D003404:Creatinine / Q000097:blood; D006801:Humans; D007275:Injections, Intravenous; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced*; D007677:Kidney Function Tests; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
D000900:Anti-Bacterial Agents; D003404:Creatinine; D003091:Colistin