Iron-catalyzed selective oxidation of N-methyl amines: highly efficient synthesis of methylene-bridged bis-1,3-dicarbonyl compounds.
Methylene-bridged bis-1,3-dicarbonyl derivatives were synthesized efficiently by iron-catalyzed oxidative reactions of 1,3-dicarbonyl compounds and N,N-dimethylaniline. Bipyrazoles and substituted 1,4-dihydropyridine were obtained by the reactions of bis-1,3-dicarbonyl compounds with hydrazines and ammonium acetate, respectively.
Li
Haijun
H
Department of Chemistry, Renmin University of China, Beijing 100872, China.
He
Zhiheng
Z
Guo
Xingwei
X
Li
Wenjuan
W
Zhao
Xuhui
X
Li
Zhiping
Z
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000138:chemical synthesis* / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D008958:Models, Molecular; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000814:Aniline Compounds; C015157:N,N-dimethylaniline; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D007501:Iron