title: The last year before the dawn of antibiotics.
abstract: Pick up any bound volume of a general medical journal of 1934 (75 years ago - within the memory of old members of the profession), and there are likely to be papers concerning the dreaded effects of the Gram positive cocci. The pneumococcus, causing often fatal lobar pneumonia in previously fit young people, and the beta-haemolytic streptococcus, producing erysipelas, septicaemia and puerperal sepsis, were especially dangerous. Volume one of the Lancet for that year, for example, contains no less than four papers on different trials of treatment for streptococcal infection as well as a long and learned leading article.
authors.affiliation: Guy's, King's and St Thomas' School of Biomedical Sciences, London, UK.
authors.forename: Harold
authors.initials: H
authors.lastname: Ellis
mesh_terms: D000900:Anti-Bacterial Agents / Q000266:history*; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D013290:Streptococcal Infections / Q000266:history* / Q000628:therapy; D000077145:Sulfanilamide; D013424:Sulfanilamides / Q000266:history; D010128:p-Aminoazobenzene / Q000031:analogs & derivatives / Q000266:history; D044482:Benzeneacetamides
chemical_list: D000900:Anti-Bacterial Agents; D000077145:Sulfanilamide; D013424:Sulfanilamides; D010128:p-Aminoazobenzene; C003359:sulfamidochrysoidine; D044482:Benzeneacetamides