Effects of Biofreeze and chiropractic adjustments on acute low back pain: a pilot study.
OBJECTIVE
This randomized controlled study was designed to determine the pain-relieving effect of Biofreeze (Performance Health Inc., Export, PA) body surface application and chiropractic adjustments on subjects with acute low back pain (LBP).


METHODS
The data were collected at the baseline, 2 weeks after treatment, and 4 weeks after treatment for final analyses. Diversified manual adjustments were provided by licensed chiropractors twice a week for 4 weeks to both control and experimental groups. Biofreeze was applied to the lower back area 3 times a day for 4 weeks in the experimental group. Outcome assessments included visual analog scale, Roland Morris Disability Questionnaire, heart rate variability for stress, and electromyography for low back muscle activity.


RESULTS
A total of 36 subjects were recruited in the study (25 male). The average age was 34 years. Significant pain reduction was found after each week of treatment in the experimental group (P < .05). The Roland Morris Disability Questionnaire did not show significant changes in both groups. There were no significant differences for pain reduction in the control group. Heart rate variability analysis showed no significant change (P > .05) in the experimental group after 4 weeks of Biofreeze and chiropractic adjustments. There were no statistically significant changes in the electromyography readings between the 2 groups.


CONCLUSIONS
Biofreeze combined with chiropractic adjustment showed significant reduction in LBP.
Zhang
John
J
Associate Director of Research, Logan College of Chiropractic, Chesterfield, MO 63017.
Enix
Dennis
D
Snyder
Brian
B
Giggey
Kristan
K
Tepe
Rodger
R
Pain. 1999 Mar;80(1-2):113-9
10204723
Spine (Phila Pa 1976). 1996 Dec 15;21(24):2826-32
9112706
Am J Vet Res. 2004 Sep;65(9):1204-10
15478766
Scand J Med Sci Sports. 1996 Aug;6(4):193-200
8896090
Conf Proc IEEE Eng Med Biol Soc. 2006;2006:4303-6
17946620
Curr Opin Neurobiol. 2003 Aug;13(4):487-92
12965298
Ann Rheum Dis. 1998 Aug;57(8):500-2
9797557
Am J Sports Med. 2003 Sep-Oct;31(5):680-4
12975186
Spine (Phila Pa 1976). 1999 Apr 1;24(7):691-7
10209800
Pflugers Arch. 1974;352(1):87-90
4475404
J Manipulative Physiol Ther. 2006 May;29(4):267-74
16690380
Biol Psychol. 2008 Feb;77(2):174-82
18023960
Pain. 2007 Jun;129(3):260-268
17134832
Brain. 2004 May;127(Pt 5):1159-71
14985268
J Manipulative Physiol Ther. 2007 Jan;30(1):31-7
17224353
J Pharm Pharmacol. 1994 Aug;46(8):618-30
7529306
Spine (Phila Pa 1976). 2007 Jan 15;32(2):E73-8
17224802
J Urol. 2007 Jun;177(6):2170-4; discussion 2174
17509311
J Bone Joint Surg Am. 2007 Feb;89(2):358-66
17272451
Spine (Phila Pa 1976). 2006 Apr 20;31(9):998-1006
16641776
Neurosci Lett. 2002 Apr 12;322(3):145-8
11897159
Altern Ther Health Med. 1996 Jan;2(1):52-65
8795873
Eur J Pain. 2006 Oct;10(7):603-14
16298532
Pain. 1983 Sep;17(1):45-56
6226917
Arch Dermatol Res. 1996 May;288(5-6):245-8
8738567
Baillieres Best Pract Res Clin Rheumatol. 1999 Sep;13(3):545-54
10562385
Spine (Phila Pa 1976). 1998 Sep 15;23(18):2014-20
9779536
Phys Sportsmed. 1989 Feb;17(2):162-8
27452025
Orthop Clin North Am. 1991 Apr;22(2):263-71
1826550
Spine (Phila Pa 1976). 1983 Mar;8(2):141-4
6222486
Behav Res Ther. 1998 May;36(5):527-35
9648328
Acta Physiol Scand. 1951 Oct 9;24(1):27-34
14877581
J Athl Train. 1998 Jan;33(1):25-9
16558480
Science. 1965 Nov 19;150(3699):971-9
5320816
Somatosens Mot Res. 1992;9(3):235-44
1414120