Spectral domain optical coherence tomographic findings at convalescent stage of acute zonal occult outer retinopathy.
OBJECTIVE
To describe the morphology of the retina at the convalescent stage of acute zonal occult outer retinopathy (AZOOR) from images obtained by spectral domain optical coherence tomography (SD-OCT).


METHODS
The visual fields, electroretinograms (ERGs), and OCT images were reviewed in two women aged 24 and 33 years. The patients were followed for one and four years, respectively.


RESULTS
In both cases, the anterior and posterior segments were almost normal, although both patients had a sudden unilateral vision decrease and photopsia. Goldmann perimetry revealed enlarged blind spots and scotomas. The ERGs were reduced in both cases. SD-OCT showed that the junction of the inner and outer segment, the IS/OS line, of the photoreceptors was irregular or lost in the affected retinas. The retina in these areas was thinner due to a decrease in the thickness of both the outer nuclear layer (ONL) and inner nuclear layer (INL) in Case 2.


CONCLUSIONS
The decrease in retinal thickness at the convalescent stage of AZOOR is most likely due to a shortening of not only the photoreceptors and ONL but also to a thinning of the INL in a severe case.
Ohta
Kouichi
K
Department of Ophthalmology, Matsumoto Dental University, shiojiri, Nagano, Japan.
Sato
Atsuko
A
Fukui
Emi
E
Arch Ophthalmol. 1985 Dec;103(12):1796-806
2866759
Arch Ophthalmol. 2007 Sep;125(9):1194-200
17846358
Acta Ophthalmol. 2008 Dec;86(8):913-6
18547281
Am J Ophthalmol. 2009 Mar;147(3):467-72
19026403
Am J Ophthalmol. 2008 Jul;146(1):111-20
18439564
J Clin Neuroophthalmol. 1993 Jun;13(2):79-97
8340485
Am J Ophthalmol. 2002 Sep;134(3):329-39
12208243