Unusually rapid growth and adult stature in an American hairless terrier puppy.
A puppy was evaluated for rapid growth and large stature. Extensive diagnostic evaluation suggested a growth hormone independent disorder. As the sole detected abnormality was elevated leptin concentration, an obesity syndrome causing leptin resistance was speculated to explain the puppy's condition but was not confirmed. Except for large body size, the puppy remained clinically normal.
Lyon
S D
SD
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Toll
J
J
Schermerhorn
T
T
D000818:Animals; D004285:Dogs / Q000254:growth & development; D005260:Female; D006130:Growth Disorders / Q000662:veterinary*; D013006:Growth Hormone / Q000097:blood; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood
D007328:Insulin; D020738:Leptin; D013963:Thyroid Hormones; D013006:Growth Hormone; D006854:Hydrocortisone