Control of tumor markers using nanotechnology.
The relevance of tumor markers in clinical diagnosis of cancer has given rise to the development of new approaches based on the use of nanoparticles to improve the features of the immunoassays developed for their control. This article reviews the usefulness of different nanoparticles to develop direct, sandwich and competitive assays for the individual and multiplexed determination of these compounds.
Gómez-Hens
A
A
Department of Analytical Chemistry, Marie Curie Annex Building, Campus of Rabanales, University of Córdoba, E-14071 Córdoba, Spain. qa1gohea@uco.es
Fernández-Romero
J M
JM
Aguilar-Caballos
M P
MP
D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis
D014408:Biomarkers, Tumor