Oncocytic sialolipoma of the submandibular gland with sebaceous differentiation: a new pathological entity.
METHODS
We report the case of an oncocytic sialolipoma of the submandibular gland with sebaceous differentiation in a 73-year-old man. The initial symptom was a right submandibular painless mass. Ultrasonography showed a hypoechoic oval mass posterior to the submandibular gland. The tumorectomy was performed with preservation of the salivary gland. The tumor was composed of mature adipose tissue surrounded by a thin fibrous capsule, multiple nodules of oncocytes, normal ductal-acinar units with focal ductal sebaceous differentiation.


CONCLUSIONS
We reviewed literature of the reported cases of mixed tumors of the salivary glands composed of mature adipose tissue with oncocytosis, salivary ducts, and acini with sebaceous differentiation.


CONCLUSIONS
Sialolipoma and lipoadenoma with or without oncocytosis and/or sebaceous differentiation should be considered organ-specific tumors with a distinct histological appearance and specific terminology.
Pusiol
Teresa
T
Institute of Anatomic Pathology, S. Maria del Carmine Hospital, Rovereto (TN), Italy.
Franceschetti
Ilaria
I
Scialpi
Michele
M
Piscioli
Irene
I
D000368:Aged; D006651:Histocytochemistry; D006801:Humans; D008067:Lipoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008297:Male; D024862:Oxyphil Cells / Q000166:cytology*; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000473:pathology; D013365:Submandibular Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography