title: Working towards an exegesis for lipids in biology.
abstract: As a field, lipidomics is in its infancy, yet it has already begun to influence lipid biochemistry in myriad ways. As with other omic technologies, the field is driven by advances in analytical chemistry, particularly by mass spectrometry. At the heart of a renaissance in lipid biochemistry, systems biology is being used to define the cellular lipome, build a comprehensive picture of metabolic interconnections, discover new molecular species and determine how lipids modulate biological functions.
authors.affiliation: Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. alex.brown@vanderbilt.edu
authors.forename: H Alex
authors.initials: HA
authors.lastname: Brown
authors.forename: Robert C
authors.initials: RC
authors.lastname: Murphy
mesh_terms: D000818:Animals; D001671:Biochemistry / Q000379:methods; D001921:Brain / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis / Q000096:biosynthesis / Q000502:physiology*; D055432:Metabolomics / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D049490:Systems Biology / Q000379:methods*
chemical_list: D008055:Lipids
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