Possible targets of "magic spots" in plant signalling.
The prokaryotic signalling molecules (p)ppGpp, also called "magic spots", regulate a wide variety of physiological activities in bacteria, including transcription, translation, and replication as well as some enzymatic activities such as those of some GTP-binding proteins, which are necessary for bacterial cells to adapt their physiology to different environmental stimuli. This response is called the stringent response. Recently, (p)ppGpp molecules and (p)ppGpp synthetase homologues, designated RSHs, have been identified in plants. At least some of the RSHs are targeted to chloroplasts. A knockdown mutation in one of the RSHs results in unusual flower development in Arabidopsis, suggesting that the plastid stringent response has important roles in the physiology of higher plants. Possible (p)ppGpp target proteins are investigated.
Masuda
Shinji
S
Graduate School of Bioscience and Biotechnology; Tokyo Institute of Technology; Yokohama Japan.
Tozawa
Yuzuru
Y
Ohta
Hiroyuki
H
Planta. 2008 Sep;228(4):553-62
18535838
J Biol Chem. 2001 Jan 12;276(2):1220-5
11035017
Plant Cell. 2006 Nov;18(11):3073-87
17122069
Int Rev Cytol. 2005;244:1-68
16157177
Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4320-4
15010537
J Biol Chem. 2004 Feb 27;279(9):7495-504
14660585
Proc Natl Acad Sci U S A. 2005 May 31;102(22):7823-8
15899978
Annu Rev Microbiol. 2008;62:35-51
18454629
Annu Rev Plant Biol. 2006;57:431-49
16669769
Structure. 2002 Nov;10(11):1581-92
12429099
Genes Cells. 1998 May;3(5):279-87
9685179
Mol Cells. 2008 Apr 30;25(2):294-300
18413999
Plant Cell Physiol. 2008 Jan;49(1):47-57
18037673
Plant Cell Physiol. 2008 Feb;49(2):135-41
18178586
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13962-7
16968770
Plant Cell. 2006 Jan;18(1):40-54
16361392
Cell. 2004 Aug 6;118(3):311-22
15294157
Mol Microbiol. 2001 Jul;41(2):289-97
11489118
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3747-52
10725385
Plant Physiol. 2008 Jul;147(3):1380-95
18502977
Plant Cell Physiol. 2003 Jan;44(1):3-9
12552141
Nucleic Acids Res. 2002 Nov 15;30(22):4985-92
12434003
J Mol Biol. 2008 Mar 21;377(2):551-64
18272182
Cell. 2004 Apr 30;117(3):299-310
15109491
EMBO J. 2004 Nov 10;23(22):4473-83
15496987
Plant Cell. 2007 Apr;19(4):1313-28
17416734
Cell. 2007 Mar 9;128(5):865-75
17350574
J Biol Chem. 2007 Dec 7;282(49):35536-45
17938177
J Mol Microbiol Biotechnol. 2001 Jan;3(1):21-35
11200227