Clozapine effectiveness in a psychiatric service in Italy.
Clozapine was administered to 28 resistant schizophrenics at psychiatric services in Bologna. At 26 weeks 62% responded. Positive and negative symptoms improved, but decrease of negative symptoms partially depended upon improvement of positive and EPS. No cases of agranulocytosis were seen. Some drop-outs were related to difficulties with psychopathological improvement.
Berardi
D
D
University of Bologna, Department of Psychiatry, 'P Ottonello', Viale C Pepoli, 5, 40123, Bologna, Italy.
Troia
M
M
Dell'atti
M
M
Bartoletti
C
C
Cantaroni
C
C
Ferrari
G
G