title: Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes.
abstract: OBJECTIVE
  There is increasing evidence that intake of sour tea (Hibiscus sabdariffa) has hypoglycemic and hypolipidemic effects and may benefit patients suffering from metabolic disorders such as diabetes. The objective of the present study was to investigate the hypolipidemic effects of sour tea in patients with diabetes and compare them with those of black tea.
  
  
  METHODS
  In this sequential randomized controlled clinical trial, 60 patients with diabetes were recruited and randomly assigned into two groups: sour tea (ST) and black tea (BT). They were instructed to consume sour tea or black tea two times a day for 1 month.
  
  
  METHODS
  Fasting blood samples were taken at the beginning and at the end of the study for evaluation of lipids, lipoproteins, and apoproteins.
  
  
  RESULTS
  Fifty-three (53) patients concluded the study. In the ST group, mean of high-density lipoprotein-cholesterol (HDLc) increased significantly (p = 0.002) at the end of the study, whereas changes in apolipoprotein-A1, and lipoprotein (a) were not significant. Also, a significant decrease in the mean of total cholesterol, low density lipoprotein-cholesterol, triglycerides, and Apo-B100 were seen in this group. In the BT group, only HDLc showed significant change (p = 0.002) at the end of the study and changes in the other measures were not statistically significant.
  
  
  CONCLUSIONS
  The results of the present study showed that ST has a significant effect on blood lipid profile in patients with diabetes.
authors.affiliation: Department of Nutrition, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. mozaffari.kh@gmail.com
authors.forename: Hassan
authors.initials: H
authors.lastname: Mozaffari-Khosravi
authors.forename: Beman-Ali
authors.initials: BA
authors.lastname: Jalali-Khanabadi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Afkhami-Ardekani
authors.forename: Farhad
authors.initials: F
authors.lastname: Fatehi
mesh_terms: D053299:Apolipoprotein B-100 / Q000097:blood; D001628:Beverages; D028241:Camellia sinensis; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D031584:Hibiscus; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D013662:Tea; D014280:Triglycerides / Q000097:blood
chemical_list: D053299:Apolipoprotein B-100; D000960:Hypolipidemic Agents; D008055:Lipids; D010936:Plant Extracts; D013662:Tea; D014280:Triglycerides; D002784:Cholesterol