title: Advanced wound therapies in the management of severe military lower limb trauma: a new perspective.
abstract: OBJECTIVE
  The purpose of this article is to describe the treatment of injuries resulting from land mine explosions using a holistic approach that includes gauze-based negative pressure wound therapy (NPWT) and encompasses wound bed preparation, exudate management, and infection control.
  
  
  METHODS
  In the treatment of 3 traumatic injuries, each requiring limb amputation, we describe the application of NPWT using the Chariker-Jeter system, which uses a single layer of saline-moistened antimicrobial gauze laid directly onto the wound bed. A silicone drain is placed on the gauze and then more gauze is placed over the drain to fill the wound. This is then covered with a clear semipermeable film, cut so that there is a 2- to 3-cm border around the wound allowing it to be sealed onto healthy skin.
  
  
  RESULTS
  In each of the cases described, we were able to achieve wound closure prior to successful skin grafting, and the patients have recovered well despite the severity of their injuries.
  
  
  CONCLUSIONS
  We discuss the potential advantages of the Chariker-Jeter system over polyurethane foam as a method of delivering NPWT in highly extensive and irregular-shaped wounds created by land mine explosions while stressing the importance of thorough and effective wound bed preparation.
authors.affiliation: The Royal Centre for Defence Medicine, Selly Oak Hospital, Birmingham B29 6JD, United Kingdom. sjeffery@nhs.net
authors.forename: S L A
authors.initials: SL
authors.lastname: Jeffery
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