title: PPAR-gamma expression in peritoneal endometriotic lesions correlates with pain experienced by patients.
abstract: Endometriosis is a significant gynecologic condition that can cause both pain and infertility and affects up to 15% of women during their reproductive years. In peritoneal endometriotic lesions, the expression of peroxisome proliferation-activated receptor gamma, a nuclear receptor with antiinflammatory and neuroprotective roles, is positively correlated with the pain reported by patients.
authors.affiliation: Department of Obstetrics and Gynecology, Inselspital, Berne University Hospital, University of Berne, Berne, Switzerland. brett.mckinnon@dkf.unibe.ch
authors.forename: Brett
authors.initials: B
authors.lastname: McKinnon
authors.forename: Nick A
authors.initials: NA
authors.lastname: Bersinger
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Huber
authors.forename: Annette
authors.initials: A
authors.lastname: Kuhn
authors.forename: Michael D
authors.initials: MD
authors.lastname: Mueller
mesh_terms: D004412:Dysmenorrhea / Q000209:etiology / Q000378:metabolism; D004414:Dyspareunia / Q000209:etiology / Q000378:metabolism; D004715:Endometriosis / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010535:Laparoscopy; D047495:PPAR gamma / Q000032:analysis*; D010147:Pain Measurement; D017699:Pelvic Pain / Q000209:etiology* / Q000378:metabolism*; D010532:Peritoneal Diseases / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D012720:Severity of Illness Index
chemical_list: D047495:PPAR gamma