title: Central venous oxygen saturation and emergency intubation--another piece in the puzzle?
abstract: A recent multicentre observational study examined the effect of emergency intubation on central venous oxygen saturation (SCVo2) in critically ill patients. The main finding was that SCVo2 significantly increases 15 minutes after emergency intubation and institution of mechanical ventilation with 100% oxygen, especially in those patients with pre-intubation SCVo2 values <70%, regardless of whether these patients suffered from severe sepsis. However, in only one-quarter of this subgroup was the SCVo2 normalized to > or =70% solely by this intervention. In contrast, in patients with pre-intubation SCVo2 > or =70%, the SCVo2 failed to increase after intubation. A rise in SCVo2 can be expected when whole body oxygen extraction remains unchanged after intubation and ventilation with pure oxygen.
authors.affiliation: Universitätsklinik für Anästhesiologie, Universität Ulm, Steinhövelstrass, 89073 Ulm, Germany. wolfgang.stahl@uni-ulm.de
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Stahl
authors.forename: Peter
authors.initials: P
authors.lastname: Radermacher
authors.forename: Michael
authors.initials: M
authors.lastname: Georgieff
authors.forename: Hendrik
authors.initials: H
authors.lastname: Bracht
mesh_terms: D001784:Blood Gas Analysis; D002405:Catheterization, Central Venous; D016638:Critical Illness / Q000628:therapy*; D004630:Emergencies; D006801:Humans; D007442:Intubation, Intratracheal; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D010101:Oxygen Consumption; D018805:Sepsis / Q000097:blood / Q000628:therapy
chemical_list: D010100:Oxygen
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