[Scientific evidence and the cost of innovations in the health-care system].
When depicting the relationship between evidence and the cost of an innovation in the health-care system, the overall risks of assessment, the redistribution of risks in a regulated market, and the ethical consequences must first be taken into account. There are also evidence-based criteria and economic considerations which are relevant when calculating the cost of an innovation. These topics can indicate, but not exhaustively deal with the complicated relationship between scientific evidence and calculating the cost of an innovation in the health-care system. The following three statements summarize the current considerations in the continuing discussion of this topic: *Scientific evidence undoubtedly exists which should be taken into consideration when calculating the cost of an innovation in the health-care system. *The existing scientific evidence is, however, not sufficient to reach such a decision. Additional information about the benefit perceived by the patient is required. *No standardized method exists to measure this additional information. Therefore, a definition problem also exists in the health-care system when setting a price according to scientific evidence.
Porzsolt
Franz
F
Klinische Okonomik, Universität Ulm, Ulm, Germany. Franz.Porzsolt@uniklinik-ulm.de
Schreyögg
Jonas
J
D003363:Cost Control / Q000639:trends; D003362:Cost-Benefit Analysis; D004059:Diffusion of Innovation; D016527:Drug Costs / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine / Q000191:economics*; D005544:Forecasting; D005858:Germany; D006801:Humans; D013677:Medical Laboratory Science / Q000191:economics*; D009313:National Health Programs / Q000191:economics*; D011788:Quality of Life; D018570:Risk Assessment; D035703:Therapies, Investigational / Q000191:economics*
Health Aff (Millwood). 2006 May-Jun;25(3):635-46
16684726
Harefuah. 2008 Jul;147(7):605-6, 662
18814519
Graefes Arch Clin Exp Ophthalmol. 2009 Jan;247(1):1-11
18843500
N Engl J Med. 2003 Sep 11;349(11):1048-55
12968089
Int J Technol Assess Health Care. 2002 Winter;18(1):94-111
11987445
Eur J Health Econ. 2007 Sep;8 Suppl 1:S3
17619919
BMC Health Serv Res. 2004 Sep 08;4(1):25
15355544
Surgery. 2008 Feb;143(2):168-71
18242329
Explore (NY). 2007 Nov-Dec;3(6):561-72
18005908
Harv Bus Rev. 2006 Apr;84(4):98-107; 148
16579417
JAMA. 2005 Nov 23;294(20):2618-22
16304076
PLoS Med. 2007 Sep;4(9):e283
17896856
Med Klin (Munich). 2008 Dec 15;103(12):836-42
19099213
BMC Health Serv Res. 2009 Mar 19;9:50
19298658
J Gen Intern Med. 2001 Oct;16(10):701-11
11679039
Health Econ Policy Law. 2009 Jan;4(Pt 1):79-98
19099618
Med Care. 2000 Jun;38(6 Suppl 1):I7-16
10843266
Eur J Health Econ. 2005 Dec;Suppl:2-10
16270212
Epidemiol Perspect Innov. 2004 Oct 04;1(1):3
15507128
Gesundheitswesen. 2004 Jan;66(1):7-14
14767785
Implement Sci. 2008 Apr 22;3:20
18430199
Can Nurse. 1993 Mar;89(3):15-7
8457968
Eur J Health Econ. 2008 Aug;9(3):205-7
18496721
Med Care Res Rev. 2002 Dec;59(4):455-81
12508705
Sci Eng Ethics. 2004 Jan;10(1):119-32
14986778
JAMA. 1999 Nov 17;282(19):1869-72
10573280
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2006 Feb;49(2):198-201
16435102
Surgery. 2008 May;143(5):582-8
18436005