Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye study.
OBJECTIVE
To examine the distribution and systemic determinants of ocular biometry as measured using partial laser interferometry in an adult Asian population.


METHODS
A population-based, cross-sectional study of 3280 persons (78.7% participation rate) ages 40 to 80 years, of Malay ethnicity residing in Singapore, was conducted. Axial ocular dimensions, including axial length (AL), anterior chamber depth (ACD), and corneal curvature (CC), were determined with partial laser interferometry. Participants had a comprehensive interview and a standardized examination.


RESULTS
After 492 persons were excluded who had undergone cataract surgery, data on 2788 subjects were available. The mean AL, ACD, and CC were 23.55, 3.10, and 7.65 mm, respectively. AL and ACD decreased with increasing age. In multivariate models that adjusted for age, sex, education, height, weight, number of reading hours, diabetes, and current smoking, longer AL was associated with being male, height, increasing weight, higher education levels, and total reading hours. Increasing CC was associated with greater age and greater height and weight after multivariable adjustment.


CONCLUSIONS
Age, sex, and stature were the most consistent predictors of the results of ocular biometry in the Singapore Malay adult population.
Lim
Laurence Shen
LS
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Saw
Seang-Mei
SM
Jeganathan
V Swetha E
VS
Tay
Wan Ting
WT
Aung
Tin
T
Tong
Louis
L
Mitchell
Paul
P
Wong
Tien Yin
TY
D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000033:anatomy & histology*; D044466:Asian People; D001699:Biometry; D001827:Body Height; D003315:Cornea / Q000033:anatomy & histology*; D003430:Cross-Sectional Studies; D005123:Eye / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007368:Interferometry; D007834:Lasers; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D017678:Sex Distribution; D012846:Singapore / Q000453:epidemiology