Case of inflammatory fibroid polyp of the esophagogastric junction.
Upper gastrointestinal endoscopy of a 25-year-old man with heartburn revealed an elevated lesion in the esophagogastric junction (EGJ). Piecemeal endoscopic mucosal resection (EMR) followed by histopathological examination led to a diagnosis of inflammatory fibroid polyp (IFP). After EMR, the heartburn persisted despite giving a proton pump inhibitor (PPI), and the residual lesion gradually enlarged and a transverse mucosal break developed on the esophageal side of it. However, the combined administration of the PPI and an H2 receptor antagonist reduced the heartburn, and led to endoscopic regression of the lesion and disappearance of the transverse mucosal break. IFP of the esophagogastric junction is extremely rare, and this case is interesting in that potent inhibition of gastric acid secretion resulted in the regression of the lesion.
Yamane
Tateki
T
Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan. yamane@jikei.ac.jp
Uchiyama
Kan
K
Ishii
Takayuki
T
Ishii
Hironori
H
Takizawa
Reo
R
Omura
Mitsuhiro
M
Fujise
Kiyotaka
K
Tajiri
Hisao
H
D000328:Adult; D004935:Esophageal Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D004943:Esophagogastric Junction; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011127:Polyps / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D054328:Proton Pump Inhibitors / Q000528:radiation effects / Q000627:therapeutic use; D013272:Stomach Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors