Water-promoted cascade synthesis of alpha-arylaldehydes from arylalkenes using N-halosuccinimides: an avenue for asymmetric oxidation using Cinchona organocatalysis.
The direct oxidation of arylalkenes into alpha-arylaldehydes is achieved for the first time in water without relying on transition metal catalysts, and a novel organocatalytic enantioselective approach is also explored to provide up to 30% ee in initial investigations.
Sharma
Abhishek
A
Natural Plant Products Division, Institute of Himalayan Bioresource Technology, CSIR, Palampur, 176061 (H.P.), India.
Sharma
Naina
N
Kumar
Rakesh
R
Sharma
Upendra K
UK
Sinha
Arun K
AK
D000475:Alkenes / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D002929:Cinchona / Q000737:chemistry*; D008823:Micelles; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013388:Succinimides / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D000475:Alkenes; D001547:Benzaldehydes; D008823:Micelles; D013388:Succinimides; D014867:Water; C032620:succinimide