Phylogenetic analysis of a near-full-length sequence of an erythrovirus genotype 3 strain isolated in Brazil.
Human parvovirus B19 is the only member of the genus Erythrovirus that causes human disease. Recent findings of several strains with considerable sequence divergence from B19 have suggested a new classification for parvovirus genotypes as 1 (B19), 2 (A-6 and LaLi) and 3 (V9). In their overall DNA sequence, the three genotypes differ by approximately 10%. Here, we report the isolation of a genotype-3-related strain named BR543 during a prospective study conducted in Sao Paulo, Brazil. Analysis of the nearly full-length genome sequence of BR543 indicates that this B19 variant sequence clusters with Gh2768, a strain from Ghana belonging to subtype 3b, and showed mostly synonymous substitutions.
Keller
Lilian Walsh
LW
Institute of Biomedical Science, Department of Microbiology, University of Sao Paulo, Prof. Lineu Prestes 1374, Sao Paulo, Brazil. lilian.keller@usp.br
Barbosa
Maria Luisa
ML
Melo
Fernando Lucas
FL
Pereira
Lilian M
LM
David-Neto
Elias
E
Lanhez
Luiz E
LE
Durigon
Edison Luiz
EL
D001483:Base Sequence; D001938:Brazil; D019218:Erythrovirus / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics; D016679:Genome, Viral / Q000235:genetics; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000821:virology; D016732:Parvovirus B19, Human / Q000235:genetics; D010802:Phylogeny