Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C.
OBJECTIVE
To report 2 cases of delayed-onset, bleb-related endophthalmitis induced by Gemella species.


METHODS
Interventional case report.


RESULTS
Two patients developed bleb-related ocular infection attributable to Gemella haemolysans and Gemella morbillorum after trabeculectomy with adjunctive mitomycin C. Both patients had thin-walled cystic filtering blebs before ocular infection. One patient underwent urgent vitrectomy with intravitreal injection of ceftazidime and vancomycin. The other received an intraocular injection of vancomycin and ceftazidime. After surgical intervention, 2 cases were administered topical levofloxacin and sulfobenzylpenicillin, and intravenous cefpirome. The DNA from the microorganism was sequenced and identified as G. haemolysans and G. morbillorum.


CONCLUSIONS
Gemella species should be added to the long list of organisms that may rarely cause bleb-associated endophthalmitis.
Sawada
Akira
A
Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu-shi 501-1194, Japan. sawadaa-gif@umin.ac.jp
Mochizuki
Kiyofumi
K
Katada
Toshihiko
T
Kawakami
Hideaki
H
Yamamoto
Tetsuya
T
Mikamo
Hiroshige
H
Watanabe
Kunitomo
K
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001768:Blister / Q000382:microbiology; D003228:Conjunctiva / Q000601:surgery; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011183:Postoperative Complications; D040141:Staphylococcaceae / Q000302:isolation & purification*; D019738:Surgically-Created Structures / Q000382:microbiology; D014130:Trabeculectomy; D014821:Vitrectomy
D000900:Anti-Bacterial Agents; D016685:Mitomycin