Orbital solitary fibrous tumor : a case report and diagnostic clues.
Orbital solitary fibrous tumor (SFT) is a rare tumor originating from the mesenchyme. We describe the clinical presentations, radiological and operative findings, and pathological features of a patient with orbital SFT. The patient was a 46-year-old female who presented with progressive proptosis advanced for 20 months. On ophthalmological examination, no visual impairment was detected, but left eye was found to be obviously protruded on exophthalmometry. Orbital magnetic resonance imaging showed a 2.5 x 2 x 2 cm, intensely enhanced mass in the left orbit, which compressed the eyeball forward and the optic nerve downward. The patient underwent frontal craniotomy with superior orbitotomy and gross total resection was performed for the tumor. The histopathological diagnosis including immunohistochemistry was a SFT. After the surgery, proptosis was markedly relieved without visual impairment. Although orbital SFT is extremely rare, it should be considered in the differential diagnosis of orbital tumors. Clinical presentations such as painless proptosis and CD34 immunoreactivity play a significant role in differentiating orbital SFT from other spindle-cell neoplasms of the orbit.
Ha
Joo Kyung
JK
Department of Neurosurgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Park
Bong Jin
BJ
Kim
Yun Hwa
YH
Lim
Young Jin
YJ
Pathol Int. 2000 Oct;50(10):808-17
11107053
Surv Ophthalmol. 2003 Sep-Oct;48(5):544-54
14499820
Surg Neurol. 2001 Oct;56(4):242-6
11738672
Mod Pathol. 1999 Nov;12(11):1034-42
10574600
Ophthalmic Plast Reconstr Surg. 2001 Sep;17(5):369-73
11642494
Int J Oral Maxillofac Surg. 2005 May;34(3):331-3
15741045
Orbit. 2006 Mar;25(1):45-50
16527776
Cancer. 1997 Apr 25;81(2):116-21
9126139
Am J Surg Pathol. 1994 Oct;18(10):992-8
7522416
Am J Surg Pathol. 1997 Nov;21(11):1354-60
9351573
Can J Ophthalmol. 1997 Dec;32(7):432-5
9435973
Br J Ophthalmol. 1979 Sep;63(9):600-6
486378
Arch Pathol Lab Med. 2003 Apr;127(4):432-9
12683870
Pathol Int. 1995 Dec;45(12):952-7
8808301
Hum Pathol. 1993 Mar;24(3):284-93
7681032
Am J Surg Pathol. 2001 Jul;25(7):846-55
11420455
Am J Surg Pathol. 1998 Dec;22(12):1501-11
9850176
Am J Clin Pathol. 1996 Aug;106(2):217-24
8712177
Ann Diagn Pathol. 2003 Jun;7(3):169-73
12808569
Arch Pathol Lab Med. 2006 Jul;130(7):1039-41
16831031
Dtsch Med Wochenschr. 2001 Jan 5;126(1-2):12-5
11200659
Diagn Cytopathol. 2001 Sep;25(3):172-6
11536441
Eur Arch Otorhinolaryngol. 2005 Feb;262(2):81-8
15316820
J Neurooncol. 2001 Aug;54(1):57-69
11763424
Ophthalmic Plast Reconstr Surg. 2004 Nov;20(6):471-3
15599253
J Craniofac Surg. 2002 Sep;13(5):641-4
12218791
J Neuroophthalmol. 2006 Sep;26(3):200-8
16966942
Acta Ophthalmol Scand. 1999 Dec;77(6):704-8
10634569
Graefes Arch Clin Exp Ophthalmol. 2002 Jul;240(7):570-4
12136289
Am J Surg Pathol. 1989 Aug;13(8):640-58
2665534
Neuroradiology. 1999 Jan;41(1):52-4
9987770
Am J Surg Pathol. 1998 Jul;22(7):863-72
9669348
Ophthalmology. 2003 Jul;110(7):1442-8
12867407
Neurosurgery. 2001 Nov;49(5):1241-5
11846919