[Influence of blood pressure lowering treatment on IPSS, Qmax in old and middle-aged male patients with essential hypertension].
OBJECTIVE
To explore the influence of blood pressure lowering treatment on the International Prostate Syndrome Score (IPSS) and maximum flow rate (Qmax) in old and middle-aged male patients with essential hypertension.


METHODS
We enrolled 193 hypertensive male patients aged 50-75 years from the rural area of Anqing, Anhui, treated them with Amlodipine for 4 weeks, and then analyzed the correlation of their baseline blood pressure and reduced blood pressure with the changes of IPSS and Qmax.


RESULTS
After 4 weeks of medication, the systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the subjects dropped by 16.8 +/- 16.7 and 8.1 +/- 7.7 mmHg respectively (P < 0.01), IPSS decreased by 2.5 +/- 5.5 points (P < 0.01) and Qmax increased by 0.2 +/- 4.7 ml/s (P = 0.46). Changes of Qmax were not significantly correlated with either the baseline or decreased blood pressure, while changes of IPSS had a significant linear correlation with the former but not with the latter.


CONCLUSIONS
Lowering blood pressure in old and middle-aged male patients with essential hypertension can prevent or alleviate the subjective symptoms of benign prostatic hyperplasia, and it reduces IPSS more significantly in those with higher baseline blood pressure.
Zhang
Xiao
X
Institute of Biomedicine, Anhui Medical University, Hefei, Anhui 230032, China.
Mao
Guang-Yun
GY
Liu
Hai-Peng
HP
Xu
Xi-Ping
XP
D000368:Aged; D001794:Blood Pressure; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000209:etiology / Q000503:physiopathology*; D016896:Treatment Outcome; D014563:Urodynamics