The emerging role of microRNAs in immune cell development and differentiation.
MicroRNAs (miRNAs) are small RNA strands (20-25 nucleotides) that regulate gene expression by translational repression as well as by messenger RNA degradation. This review will examine the application and function of miRNAs in immune cell development and differentiation.
Liang
Tie-Jun
TJ
The Department of Digestive Diseases, Shandong University Provincial Hospital, Jinan, Shandong Province, China.
Qin
Cheng-Yong
CY
D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology; D002454:Cell Differentiation; D015870:Gene Expression; D006410:Hematopoiesis / Q000235:genetics / Q000276:immunology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics / Q000276:immunology; D016399:Lymphoma, T-Cell / Q000235:genetics / Q000276:immunology; D035683:MicroRNAs / Q000235:genetics / Q000276:immunology*; D009000:Monocytes / Q000166:cytology / Q000276:immunology; D009369:Neoplasms / Q000235:genetics / Q000276:immunology; D012334:RNA, Neoplasm / Q000235:genetics / Q000276:immunology; D043244:Ribonuclease III / Q000378:metabolism; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology
D035683:MicroRNAs; D012334:RNA, Neoplasm; D043244:Ribonuclease III