title: The effects of human amniotic membrane and periosteal autograft on tendon healing: experimental study in rabbits.
abstract: In this study, the effects of periosteal autograft and human amniotic membrane on tendon healing were compared. Forty-two New Zealand rabbits were divided into three groups. Flexor digitorum fibularis tendons were cut and repaired with a modified Kessler technique and circumferential sutures in all groups. Tendon repair alone was carried out in group 1, tendon repair and application of human amniotic membrane was done in group 2 and tendon repair and application of periosteal autograft was done in group 3. Biomechanical and histopathological examinations were done 2 and 6 weeks postoperatively. Biomechanical examination showed that group 3 was the strongest at weeks 2 and 6. Adhesion, inflammation and new bone formation showed no difference between groups at week 2. However, adhesion formation was found to be less in groups 2 and 3 than group 1 at week 6. The application of periosteal autograft might be useful in repair of tendon injuries.
authors.affiliation: Bursa High Specialty Research and Training Hospital, Clinic of Orthopaedics and Traumatology Yildirim, Department of Surgery, Veterinary Faculty, Uludağ University, Görükle, Bursa, Turkey. ozturkalp16@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Ozbölük
authors.forename: Y
authors.initials: Y
authors.lastname: Ozkan
authors.forename: A
authors.initials: A
authors.lastname: Oztürk
authors.forename: N
authors.initials: N
authors.lastname: Gül
authors.forename: R M
authors.initials: RM
authors.lastname: Ozdemir
authors.forename: K
authors.initials: K
authors.lastname: Yanik
mesh_terms: D000650:Amnion / Q000637:transplantation*; D000818:Animals; D004195:Disease Models, Animal; D006225:Hand; D006801:Humans; D010521:Periosteum / Q000637:transplantation*; D011817:Rabbits; D013536:Suture Techniques; D013708:Tendon Injuries / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013718:Tensile Strength; D000267:Tissue Adhesions / Q000209:etiology / Q000473:pathology / Q000517:prevention & control; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology*