title: Is it time for a new paradigm in calcific aortic valve disease?
authors.forename: David S
authors.initials: DS
authors.lastname: Owens
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Otto
mesh_terms: D000367:Age Factors; D001011:Aorta / Q000503:physiopathology; D001021:Aortic Valve / Q000473:pathology* / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000097:blood / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D002114:Calcinosis / Q000097:blood / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D004548:Elasticity; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology; D006349:Heart Valve Diseases / Q000097:blood / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism; D010974:Platelet Aggregation; D011673:Pulsatile Flow; D018570:Risk Assessment; D012307:Risk Factors; D012598:Sclerosis
chemical_list: D009569:Nitric Oxide