Disentangling emotion processes in borderline personality disorder: physiological and self-reported assessment of biological vulnerability, baseline intensity, and reactivity to emotionally evocative stimuli.
This study investigated M. Linehan's (1993) theory that individuals meeting criteria for borderline personality disorder (BPD) have high biological vulnerability to emotion dysregulation, including high baseline emotional intensity and high reactivity to emotionally evocative stimuli. Twenty individuals with BPD, 20 age-matched individuals with generalized social anxiety disorder (SAD), and 20 age-matched normal controls (NCs) participated in 2 separate emotion induction conditions, a standardized condition, and a personally relevant condition. Respiratory sinus arrhythmia (RSA), skin conductance response (SCR), and self-report measures were collected throughout the experiment. BPD participants displayed heightened biological vulnerability compared with NCs as indicated by reduced basal RSA. BPD participants also exhibited high baseline emotional intensity, characterized by heightened SCR and heightened self-reported negative emotions at baseline. However, the BPD group did not display heightened reactivity, as their physiological and self-reported changes from baseline to the emotion inductions tasks were not greater than the other 2 groups.
Kuo
Janice R
JR
Department of Psychology, Stanford University, Stanford, CA 94305, USA. jrkuo@stanford.edu
Linehan
Marsha M
MM
D000223:Adaptation, Psychological / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004562:Electrocardiography; D004644:Emotions / Q000502:physiology*; D005260:Female; D005583:Fourier Analysis; D005712:Galvanic Skin Response / Q000502:physiology; D006801:Humans; D008297:Male; D010698:Phobic Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D011603:Psychophysiology; D012307:Risk Factors; D012647:Self-Assessment; D012815:Signal Processing, Computer-Assisted; D012931:Social Environment; D013564:Sympathetic Nervous System / Q000503:physiopathology; D055815:Young Adult
J Psychiatr Res. 2005 Jan;39(1):85-92
15504426
Biol Psychiatry. 2003 Jul 15;54(2):163-71
12873806
J Psychiatr Res. 2006 Aug;40(5):419-27
16239012
J Nerv Ment Dis. 2002 Oct;190(10):693-6
12409863
J Pers Disord. 2002 Jun;16(3):201-14
12136678
Clin Auton Res. 2000 Jun;10(3):123-30
10954070
Psychiatry Res. 2004 Apr 15;126(1):33-42
15081625
Compr Psychiatry. 1987 Nov-Dec;28(6):530-5
3691077
Am J Psychiatry. 1985 Feb;142(2):207-12
3970245
Br J Psychiatry. 2002 Jun;180:536-42
12042233
Psychophysiology. 2006 Nov;43(6):612-22
17076818
Psychiatr Serv. 2006 Feb;57(2):254-7
16452705
Eur Neuropsychopharmacol. 2006 Jul;16 Suppl 2:S109-18
16737802
Am J Psychiatry. 1997 Aug;154(8):1101-6
9247396
Arch Gen Psychiatry. 2006 Jul;63(7):757-66
16818865
J Abnorm Psychol. 1983 Aug;92(3):263-75
6619404
Biol Psychiatry. 1999 Apr 15;45(8):1056-8
10386191
J Am Coll Cardiol. 1994 Dec;24(7):1700-7
7963118
Biol Psychiatry. 2004 Feb 1;55(3):284-90
14744470
J Neuropsychiatry Clin Neurosci. 2003 Spring;15(2):145-54
12724454
Dev Psychobiol. 1996 Dec;29(8):697-712
8958482
J Psychiatr Res. 2001 Nov-Dec;35(6):307-12
11684137
Hosp Community Psychiatry. 1991 Oct;42(10):1015-21
1959892
Am J Psychiatry. 1999 Oct;156(10):1550-6
10518165
Am J Psychiatry. 2000 Apr;157(4):601-8
10739420
Biol Psychiatry. 1993 Mar 1;33(5):326-34
8471690
Dev Psychobiol. 2000 Dec;37(4):209-20
11084602
Biol Psychiatry. 1996 Feb 15;39(4):255-66
8645772
J Psychiatr Res. 2006 Aug;40(5):448-53
16690085
Psychophysiology. 1997 Nov;34(6):623-48
9401419
Lancet. 2004 Jul 31-Aug 6;364(9432):453-61
15288745
Psychophysiology. 1992 Nov;29(6):742-50
1461961
Ann Clin Psychiatry. 1994 Mar;6(1):27-31
7951642
Hosp Community Psychiatry. 1986 Apr;37(4):386-90
2870978
Biol Psychiatry. 2002 Jun 15;51(12):951-63
12062878
J Clin Psychiatry. 2008 Apr;69(4):533-45
18426259
Ann N Y Acad Sci. 1986;487:281-93
2882718
Am J Psychiatry. 2002 May;159(5):784-8
11986132
Brain Cogn. 2007 Oct;65(1):69-76
17659821
J Psychol. 1993 Nov;127(6):657-76
8301618
Psychol Rev. 1991 Oct;98(4):459-87
1660159
Acta Psychiatr Scand. 2005 May;111(5):372-9
15819731
J Affect Disord. 1994 Dec;32(4):271-5
7897091
J Abnorm Psychol. 2007 Aug;116(3):578-88
17696713
Biol Psychiatry. 1998 Nov 15;44(10):1054-9
9821570
Psychiatry Res. 2003 Apr 1;122(3):193-8
12694893
J Psychiatry Neurosci. 2006 May;31(3):181-8
16699604
Bull Menninger Clin. 1987 May;51(3):261-76
3580661
Biol Psychiatry. 2003 Dec 15;54(12):1427-36
14675808
Arch Gen Psychiatry. 2000 Dec;57(12):1115-22
11115325
Clin Psychol Rev. 2008 Jan;28(1):75-91
17544188
J Psychosom Res. 1998 Jan;44(1):133-51
9483470
Psychiatry Res. 2007 Apr 15;150(3):265-75
17321599
J Psychiatr Res. 2001 Mar-Apr;35(2):111-8
11377440
Psychophysiology. 1990 Sep;27(5):586-98
2274622
Arch Gen Psychiatry. 1987 Nov;44(11):970-5
3675137
Psychophysiology. 1995 Jul;32(4):301-18
7652107
Dev Psychopathol. 2001 Spring;13(2):183-214
11393643
J Nerv Ment Dis. 1997 Apr;185(4):240-6
9114809
Am J Psychiatry. 2005 May;162(5):883-9
15863789
Eur Arch Psychiatry Clin Neurosci. 2008 Apr;258(3):137-43
17990048
Behav Res Ther. 2005 Sep;43(9):1173-85
16005704
Arch Gen Psychiatry. 2001 Jun;58(6):590-6
11386989
Monogr Soc Res Child Dev. 1994;59(2-3):167-86
7984159
Arch Gen Psychiatry. 2001 Aug;58(8):737-45
11483139
Behav Ther. 2016 Nov;47(6):838-853
27993336
Behav Res Ther. 2005 Feb;43(2):257-68
15629754
Psychophysiology. 1981 May;18(3):232-9
7291438
Neurosci Biobehav Rev. 1995 Summer;19(2):225-33
7630578
J Pers Disord. 2000 Winter;14(4):339-51
11204341
Am J Psychiatry. 1998 Dec;155(12):1733-9
9842784
Acta Psychiatr Scand. 1990 Jun;81(6):554-9
2378249
Am J Psychiatry. 2003 Feb;160(2):274-83
12562573
Psychiatr Clin North Am. 2000 Mar;23(1):27-40, vi
10729929
Arch Psychiatr Nurs. 1996 Feb;10(1):32-40
8904033
Psychiatry Res. 2000 Sep 25;96(1):1-13
10980322
J Abnorm Psychol. 1995 Aug;104(3):471-89
7673571