title: [A case of unresectable advanced pancreatic cancer treated by gemcitabine-based chemotherapy following cancer pain alleviation by low-dose matrix-type transdermal fentanyl].
abstract: Cancer pain often makes patient's performance status worsen and is one of the difficulties in anti-cancer therapy. We report a case of unresectable advanced pancreatic cancer with cancer pain, which was treated by matrix-type transdermal fentanyl following slow-releasing oxycodone, which caused severe constipation. Rotation to matrix-type transdermal fentanyl (Durotep MT 2.1 mg) releaved severe constipation as well as cancer pain. The patient could take gemcitabine-based chemotherapy. Low-dose matrix-type transdermal fentanyl (Durotep MT 2.1 mg) is useful for opioid rotation from low-dose morphine or oxycodone with uncontrolled side effects, and it contributes to continuation of anti-cancer therapy.
authors.affiliation: Cancer Support Team, Osaka National Hospital, National Hospital Organization.
authors.forename: Kazuyo
authors.initials: K
authors.lastname: Matsuyama
authors.forename: Eriko
authors.initials: E
authors.lastname: Satomi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ueno
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Inoue
authors.forename: Mari
authors.initials: M
authors.lastname: Oike
authors.forename: Kinuyo
authors.initials: K
authors.lastname: Todaka
authors.forename: Tetsuhiko
authors.initials: T
authors.lastname: Yoshida
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sekiyama
authors.forename: Hideto
authors.initials: H
authors.lastname: Hirotsune
authors.forename: Kiyomichi
authors.initials: K
authors.lastname: Sueta
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Shoji
authors.initials: S
authors.lastname: Nakamori
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Tsujinaka
authors.forename: Katsuya
authors.initials: K
authors.lastname: Komori
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D010148:Intractable Pain / Q000188:drug therapy*; D010190:Pancreatic Neoplasms / Q000188:drug therapy*; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D005283:Fentanyl; D000093542:Gemcitabine