Altered resting and exercise respiratory physiology in obesity.
Obesity, particularly severe obesity, affects resting and exercise-related respiratory physiology. Severe obesity classically produces a restrictive ventilatory abnormality characterized by reduced expiratory reserve volume. Obstructive ventilatory abnormality may also be associated with abdominal obesity. Decreased peak work rates are usually seen among obese subjects in a setting of normal or decreased ventilatory reserve and normal cardiovascular response to exercise. Weight loss may reverse many adverse physiologic consequences of severe obesity on the respiratory system.
Sood
Akshay
A
Department of Medicine, 1 University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USA. asood@salud.unm.edu
D015444:Exercise / Q000502:physiology*; D006801:Humans; D009765:Obesity / Q000150:complications / Q000378:metabolism / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000502:physiology; D012123:Pulmonary Ventilation / Q000502:physiology; D015656:Respiratory Mechanics / Q000502:physiology*; D012132:Respiratory Muscles / Q000502:physiology; D012146:Rest / Q000502:physiology*
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