Clinical observation of Yinzhihuang Oral Liquid on prevention of the premature infantile jaundice.
OBJECTIVE
To observe the clinical efficacy of Yinzhihuang Oral Liquid (YOL) to prevent the premature infantile jaundice.


METHODS
After excluded hemolytic, suffocation, infection, and the very low birth weight, 242 cases of premature infants were randomly assigned to two groups, the treatment group and the control group. Both groups were taken conventional procedures, such as warmth, feeding, and blood glucose monitoring, and the treated group was administered YOL 5 mL each time, twice daily additionally, and the control group without any treatment. The percutaneous bilirubin and blood cells were observed every day.


RESULTS
Compared the two groups, the jaundice indices were more significantly different at 24-48 h, 48-72 h, and more than 72 h (P<0.05), but not statistically different at 0-24 h (P>0.05). Hemoglobin, reticulocyte, platelets, and leucocyte were not significantly different between the two groups (P>0.05).


CONCLUSIONS
YOL as an early intervention has positive significance to decrease the incidence of pathological jaundice in the premature infants, and no significant impact on the blood cells.
Chen
Sheng-ping
SP
Department of Obstetrics and Gynecology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. bingmchen@sina.com
Tian
Li-li
LL
Liu
Feng-ling
FL
D000284:Administration, Oral; D001663:Bilirubin / Q000378:metabolism; D001773:Blood Cells / Q000187:drug effects / Q000378:metabolism; D004304:Dosage Forms; D004334:Drug Administration Schedule; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000517:prevention & control*; D007567:Jaundice, Neonatal / Q000517:prevention & control*; D008297:Male; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D016896:Treatment Outcome
D004304:Dosage Forms; D004365:Drugs, Chinese Herbal; C070600:yin zhi huang; D001663:Bilirubin
Clin Perinatol. 2000 Mar;27(1):171-9, vii
10690570