eIMRT: a web platform for the verification and optimization of radiation treatment plans.
The eIMRT platform is a remote distributed computing tool that provides users with Internet access to three different services: Monte Carlo optimization of treatment plans, CRT & IMRT treatment optimization, and a database of relevant radiation treatments/clinical cases. These services are accessible through a user-friendly and platform independent web page. Its flexible and scalable design focuses on providing the final users with services rather than a collection of software pieces. All input and output data (CT, contours, treatment plans and dose distributions) are handled using the DICOM format. The design, implementation, and support of the verification and optimization algorithms are hidden to the user. This allows a unified, robust handling of the software and hardware that enables these computation-intensive services. The eIMRT platform is currently hosted by the Galician Supercomputing Center (CESGA) and may be accessible upon request (there is a demo version at http://eimrt.cesga.es:8080/eIMRT2/demo; request access in http://eimrt.cesga.es/signup.html). This paper describes all aspects of the eIMRT algorithms in depth, its user interface, and its services. Due to the flexible design of the platform, it has numerous applications including the intercenter comparison of treatment planning, the quality assurance of radiation treatments, the design and implementation of new approaches to certain types of treatments, and the sharing of information on radiation treatment techniques. In addition, the web platform and software tools developed for treatment verification and optimization have a modular design that allows the user to extend them with new algorithms. This software is not a commercial product. It is the result of the collaborative effort of different public research institutions and is planned to be distributed as an open source project. In this way, it will be available to any user; new releases will be generated with the new implemented codes or upgrades.
Pena
Javier
J
Departamento de Fílsica de Partículas, Facultade de Física, Universidade de Santiago de Compostela, Spain.
González-Castaño
Diego M
DM
Departamento de Fílsica de Partículas, Facultade de Física, Universidade de Santiago de Compostela, Spain.
Gómez
Faustino
F
Departamento de Fílsica de Partículas, Facultade de Física, Universidade de Santiago de Compostela, Spain.
Gago-Arias
Araceli
A
Departamento de Fílsica de Partículas, Facultade de Física, Universidade de Santiago de Compostela, Spain.
González-Castaño
Francisco J
FJ
Departamento de Enxeñería Telemática, Escola Técnica Superior de Enxeñería das Telecomunicacións, Universidade de Vigo, Spain.
Rodríguez-Silva
Daniel
D
Departamento de Enxeñería Telemática, Escola Técnica Superior de Enxeñería das Telecomunicacións, Universidade de Vigo, Spain.
Gómez
Andrés
A
Centro de Supercomputación de Galicia, Santiago de Compostela, Spain.
Mouriño
Carlos
C
Centro de Supercomputación de Galicia, Santiago de Compostela, Spain.
Pombar
Miguel
M
Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
Sánchez
Manuel
M
Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
D020407:Internet; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012984:Software
Int J Radiat Oncol Biol Phys. 2003 May 1;56(1):58-68
12694824
Med Phys. 1998 Aug;25(8):1424-34
9725129
Med Phys. 2003 May;30(5):979-85
12773007
Phys Med Biol. 2007 Jul 7;52(13):N297-308
17664568
Phys Med Biol. 2004 Aug 7;49(15):3465-81
15379026
Med Biol Eng Comput. 2008 Apr;46(4):373-80
17828563
Med Phys. 1999 Nov;26(11):2390-6
10587222
Med Phys. 2002 Mar;29(3):391-402
11930914
Med Phys. 1995 May;22(5):503-24
7643786
Med Phys. 2000 Apr;27(4):701-11
10798692
Med Phys. 2002 Jul;29(7):1514-27
12148734
Med Phys. 2000 Jun;27(6):1238-45
10902552
Int J Clin Oncol. 2005 Feb;10(1):26-9
15729597
Med Phys. 2003 Mar;30(3):301-11
12674229
Phys Med Biol. 2003 Jul 21;48(14):2101-21
12894973
Med Phys. 2003 Jul;30(7):1909-13
12906209
Med Phys. 1998 May;25(5):656-61
9608475
Phys Med Biol. 1989 Oct;34(10):1349-70
2682694
Med Phys. 2004 May;31(5):1141-52
15191303
Med Phys. 2004 Jun;31(6):1546-57
15259659
Phys Med Biol. 2007 Aug 21;52(16):4981-92
17671348
Phys Med Biol. 2001 Apr;46(4):1163-86
11324958
Med Phys. 2007 Mar;34(3):1076-84
17441253
Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):301-20
16289912
Med Dosim. 2001 Summer;26(2):189-97
11444521
Med Phys. 1997 Jul;24(7):1157-61
9243478
Med Phys. 2001 Aug;28(8):1696-702
11548939
Med Phys. 1997 Feb;24(2):149-60
9048355
Med Phys. 2003 Feb;30(2):144-57
12607832
Med Phys. 2001 Jul;28(7):1322-37
11488562
Phys Med Biol. 2008 Sep 7;53(17):4573-93
18678929
Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1565-74
12459386