title: Prognostic factor on optimal debulking surgery by maximum effort for stage IIIC epithelial ovarian cancer.
abstract: OBJECTIVE
  The aim of this study was to assess the prognostic factor of radical surgery in patients with stage IIIc ovarian cancer.
  
  
  METHODS
  Fifty-two patients were subjected to the study. The complete resection or optimal primary cytoreductive surgery (OPCS) was set as the maximum effort, and the accomplishment rate and prognosis were assessed. In addition, the poor prognosis cases among the OPCS-accomplished were evaluated with several factors based on univariate and multivariate analyses.
  
  
  RESULTS
  The OPCS accomplishment rate was 84.6%. A worse prognosis was obtained in the more-than-4-weeks-delayed postoperative chemotherapy group, assessing poor-outcome cases in the OPCS group. A case that required more than three colon resections was the significant factor for the delay of postoperative chemotherapy.
  
  
  CONCLUSIONS
  OPCS should be performed with maximum effort to improve the prognosis of stage IIIc ovarian cancer. We should avoid any delay in starting postoperative chemotherapy. In cases that require more than three colon resections, it seems that 'perioperative management' should be reconsidered and that priority should be given to postoperative management so that chemotherapy can be started soon after the operation.
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan. teralfa@tokyo-med.ac.jp
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Terauchi
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Nishi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Moritake
authors.forename: Yukari
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Takeo
authors.initials: T
authors.lastname: Nagashima
authors.forename: Takamoto
authors.initials: T
authors.lastname: Onodera
authors.forename: Atsuya
authors.initials: A
authors.lastname: Fujito
authors.forename: Daiei
authors.initials: D
authors.lastname: Nakayama
authors.forename: Keiichi
authors.initials: K
authors.lastname: Isaka
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011379:Prognosis