title: Spinal neuroarthropathy associated with Guillain-Barré syndrome.
abstract: Since the rarefaction of neurosyphilis, axial neuroarthropathy is mostly secondary to spinal cord pathologies. Peripheral manifestations of neuroarthropathy resulting from Guillain-Barré syndrome have already been reported but to our knowledge, this is the first case of a patient diagnosed with axial involvement. After the acute phase, a 47-year-old woman suffered of paraparesia with a partial loss of sensibility under the tenth thoracic vertebra. As a consequence, she developed first of all neuroarthropathy of both knees and few years later, a spinal involvement was discovered. Multiple surgeries of both knees and of the spine were required, due to non-union, relapse, and infection. Natural evolution of Charcot spine remains unknown. Surgical treatment is recommended but even with circumferential fusion, failures do frequently occur. This observation allows us to report an original case and to discuss the etiology of axial neuroarthropathy, the classical radiographic findings, and the inherent difficulties of its treatment.
authors.affiliation: Hospital Raymond Poincaré, Orthopedic Surgery Department, 104, bd Raymond Poincaré, 92380 Garches, France. raphaeljameson@yahoo.fr
authors.forename: Raphael
authors.initials: R
authors.lastname: Jameson
authors.forename: Christian
authors.initials: C
authors.lastname: Garreau de Loubresse
authors.forename: Ali
authors.initials: A
authors.lastname: Maqdes
mesh_terms: D001177:Arthropathy, Neurogenic / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D020275:Guillain-Barre Syndrome / Q000150:complications*; D006801:Humans; D016268:Internal Fixators; D008875:Middle Aged; D010292:Paresthesia / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D013122:Spinal Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome; D021801:Zygapophyseal Joint / Q000294:innervation* / Q000473:pathology / Q000503:physiopathology
references.citation: J Bone Joint Surg Am. 1959 Mar;41-A(2):336-40
references.pmid: 13630968
references.citation: Lond Med Phys J. 1831 Sep;11(63):210-218
references.pmid: 30495700
references.citation: J Spinal Disord Tech. 2004 Aug;17(4):326-30
references.pmid: 15280764
references.citation: Emerg Radiol. 2007 Sep;14(4):265-9
references.pmid: 17554573
references.citation: J Bone Joint Surg Am. 1985 Jun;67(5):771-6
references.pmid: 3997930
references.citation: Spine (Phila Pa 1976). 1992 Jun;17(6 Suppl):S103-8
references.pmid: 1631708
references.citation: Br Med J. 1949 Feb 19;1(4598):311
references.pmid: 18109341
references.citation: Spine (Phila Pa 1976). 2005 Jun 1;30(11):E315-22
references.pmid: 15928542
references.citation: Foot Ankle Int. 2006 Dec;27(12):1156-8
references.pmid: 17207449
references.citation: Radiology. 1974 Apr;111(1):1-16
references.pmid: 4816105
references.citation: Spinal Cord. 2002 Sep;40(9):481-3
references.pmid: 12185610
references.citation: Proc R Soc Med. 1961 Sep;54:823-4
references.pmid: 14492094
references.citation: Spine J. 2008 Jul-Aug;8(4):691-5
references.pmid: 17602884
references.citation: Clin Orthop Relat Res. 1988 Nov;(236):175-9
references.pmid: 2460276
references.citation: Foot Ankle Int. 2005 Jan;26(1):46-63
references.pmid: 15680119
references.citation: Neurology. 2005 Jan 25;64(2):246-53
references.pmid: 15668421
references.citation: Neurosurgery. 1991 Feb;28(2):273-7
references.pmid: 1997897
references.citation: Arch Phys Med Rehabil. 1997 Feb;78(2):221-5
references.pmid: 9041906
references.citation: Spine (Phila Pa 1976). 1980 Nov-Dec;5(6):558-67
references.pmid: 7466464
references.citation: Arch Phys Med Rehabil. 2008 Mar;89(3):568-71
references.pmid: 18295639
references.citation: Spine (Phila Pa 1976). 1990 Jan;15(1):54-6
references.pmid: 2326701
references.citation: J Bone Joint Surg Am. 1967 Jan;49(1):1-30
references.pmid: 4163089
references.citation: J Ky Med Assoc. 1995 Feb;93(2):48-52
references.pmid: 7884293
references.citation: J Spinal Disord. 1991 Sep;4(3):319-28
references.pmid: 1802163
references.citation: J Spinal Disord Tech. 2007 Feb;20(1):85-8
references.pmid: 17285059