Iron-catalyzed annulations of 2-(2-alkynyl)phenoxy)-1-arylethanones leading to substituted naphthalen-1-ols.
A novel intramolecular annulation of 1-(2-alkynylphenoxy)propan-2-ones catalyzed by iron, an economical and environmentally-benign transition metal, has been developed; this new atom-economical route includes dual C-H functionalizations to construct the naphthalen-1-ol or anthracen-1-ol skeletons.
Wang
Zhi-Qiang
ZQ
Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha 410081, China.
Liang
Yun
Y
Lei
Yong
Y
Zhou
Ming-Bo
MB
Li
Jin-Heng
JH
D000480:Alkynes / Q000737:chemistry*; D000873:Anthracenes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007501:Iron / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry*
D000480:Alkynes; D000873:Anthracenes; D009281:Naphthalenes; C031721:naphthalene; D007501:Iron; C034020:anthracene