The dispersin-encoding gene (aap) is not restricted to enteroaggregative Escherichia coli.
The presence of the enteroaggregative Escherichia coli (EAEC) virulence genes aatA, aap, and aggR was assayed in strains of different diarrheagenic E. coli pathotypes and nonpathogenic E. coli. The dispersin-encoding gene (aap) was detected in EAEC, diffusely adherent E. coli, and nonpathogenic E. coli, demonstrating that molecular diagnostics of EAEC based on aap detection may identify non-EAEC strains.
Monteiro
Bianca T
BT
Laboratório de Bacteriologia, Instituto Butantan, São Paulo, SP, 05503-900, Brazil.
Campos
Leila C
LC
Sircili
Marcelo P
MP
Franzolin
Marcia R
MR
Bevilacqua
Luciano F
LF
Nataro
James P
JP
Elias
Waldir P
WP
D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D004926:Escherichia coli / Q000145:classification / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics*; D006801:Humans; D015534:Trans-Activators / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics*
C479827:AAP protein, E coli; C512825:AatA protein, E coli; C088603:AggR protein, E coli; D001425:Bacterial Outer Membrane Proteins; D029968:Escherichia coli Proteins; D015534:Trans-Activators; D037521:Virulence Factors