The relationship of amelogenesis imperfecta and nephrocalcinosis syndrome.
OBJECTIVE
To analyze the prevalence and associated oral findings of nephrocalcinosis in a group of patients affected with amelogenesis imperfecta (AI). The relationship between types of AI and nephrocalcinosis were also evaluated.


METHODS
This study examines patients who were referred to Pediatric Dentistry Department of SDU between the years of 2002-2007 and who, upon clinical and radiological examination, were diagnosed with AI and treated. Patients were offered information about the possibility of nephrocalcinosis syndrome. Patients who agreed to have tests carried out on their renal system were advised to visit the department of nephrology at the clinic.


RESULTS
Suspicious radiopacity was observed during renal ultrasonography of a controlled number of patients with hypoplastic type AI. Laboratory results revealed low Ca values (100-300 mg/days) and normal P values (0.4-1.3 g/days). Delayed eruption, gingival hyperplasia, pulp stones and orthodontic problems were also observed in the same patient groups.


CONCLUSIONS
Although renal findings were observed in a few patients, pediatric dentists are the doctors who are the first to have early contact with this patient group. Because of the potential risk of nephrocalcinosis, early diagnosis may offer good prognosis.
Kirzioglu
Zuhal
Z
Süleyman Demirel University, Faculty of Dentistry, Department of Paediatric Dentistry, Isparta, Türkiye.
Ulu
K Gorkem
KG
Sezer
M Tugrul
MT
Yüksel
Seref
S
D000293:Adolescent; D000567:Amelogenesis Imperfecta / Q000150:complications*; D002648:Child; D006801:Humans; D009397:Nephrocalcinosis / Q000150:complications* / Q000453:epidemiology*; D015995:Prevalence; D013577:Syndrome