title: The painful lesson of analgesic drugs: never underestimate the complexity of biological systems.
authors.forename: Filippo
authors.initials: F
authors.lastname: Crea
authors.forename: Simona
authors.initials: S
authors.lastname: Giubilato
mesh_terms: D000700:Analgesics / Q000009:adverse effects*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000188:drug therapy*; D052246:Cyclooxygenase 2 Inhibitors / Q000009:adverse effects*; D004730:Endothelium, Vascular / Q000187:drug effects* / Q000503:physiopathology*; D006801:Humans
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors