title: Intraspinal dermoid and epidermoid tumors: report of 18 cases and reappraisal of the literature.
abstract: Intraspinal dermoid and epidermoid tumors are two histopathological subtypes of cutaneous inclusion tumors of the spine. This classification is based on obsolete embryological knowledge. In fact, according to current embryology, both tumor types consist of ectodermal derivatives. Therefore, we hypothesized that dermoid and epidermoid tumors do not differ in clinical practice. To explore this hypothesis, we studied the clinical, radiological and intraoperative findings of 18 patients, and related these findings to the histopathological characteristics of the tumor. No differences were found between dermoid and epidermoid tumors regarding clinical presentation, radiological examination and outcome, while intraoperative diagnosis by the surgeon correlated with the histopathological diagnosis in only 8 of 18 cases. Therefore, the histopathological difference between intraspinal dermoid and epidermoid tumors is not important in clinical practice and should be avoided. A new nomenclature is proposed in which both tumor types are referred to as 'spinal cutaneous inclusion tumors'.
authors.affiliation: Department of Neurosurgery, University Medical Center Maastricht, Maastricht, The Netherlands. jaspervanaalst@yahoo.com
authors.forename: J
authors.initials: J
authors.lastname: van Aalst
authors.forename: F
authors.initials: F
authors.lastname: Hoekstra
authors.forename: E A M
authors.initials: EA
authors.lastname: Beuls
authors.forename: E M J
authors.initials: EM
authors.lastname: Cornips
authors.forename: J W
authors.initials: JW
authors.lastname: Weber
authors.forename: D A
authors.initials: DA
authors.lastname: Sival
authors.forename: D H K V
authors.initials: DH
authors.lastname: Creytens
authors.forename: J S H
authors.initials: JS
authors.lastname: Vles
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003884:Dermoid Cyst / Q000175:diagnosis* / Q000601:surgery*; D004814:Epidermal Cyst / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000601:surgery*