title: Hyperpolarized gas MR Imaging of the lung: current status as a research tool.
abstract: Hyperpolarized gas magnetic resonance imaging has been explored extensively as a promising tool for the quantitative evaluation of regional pulmonary pathophysiology. This noninvasive technique is capable of providing both structural information down to the level of the alveolar microstructure and functional information, such as dynamic ventilation, intrapulmonary partial pressure of oxygen, and alveolar surface area. This study reviews the role of hyperpolarized 3-helium and 129-xenon magnetic resonance imaging in this research.
authors.affiliation: Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Shin
authors.initials: S
authors.lastname: Matsuoka
authors.forename: Samuel
authors.initials: S
authors.lastname: Patz
authors.forename: Mitchell S
authors.initials: MS
authors.lastname: Albert
authors.forename: Yanping
authors.initials: Y
authors.lastname: Sun
authors.forename: Rahim R
authors.initials: RR
authors.lastname: Rizi
authors.forename: Warren B
authors.initials: WB
authors.lastname: Gefter
authors.forename: Hiroto
authors.initials: H
authors.lastname: Hatabu
mesh_terms: D006371:Helium; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014978:Xenon
chemical_list: D006371:Helium; D014978:Xenon