Conservation of protein phosphorylation sites within gene families and across species.
Recent large scale phosphoproteomics studies have helped identify many phosphorylation sites of both membrane and soluble proteins. In most cases the relevance of specific sites has yet to be established whereas in a small number of cases their potency in modulating protein activity is evident. With the increasing amount of data it is becoming clear that phosphosites are often conserved within protein families, pointing to generic regulatory mechanisms. In addition, such mechanisms may be conserved across species. In this addendum evidence is presented for these phenomena occurring in rice and Arabidopsis.
Maathuis
Frans Jm
FJ
Biology Department; University of York; York UK.
Plant Cell. 2004 Sep;16(9):2394-405
15308754
Mol Cell Proteomics. 2007 Jul;6(7):1198-214
17317660
J Exp Bot. 2006;57(7):1523-7
16531460
Trends Plant Sci. 2007 Sep;12(9):404-11
17765599
Plant J. 2007 Sep;51(5):931-40
17651370
Plant J. 2008 Oct;56(1):146-56
18557835
Proteomics. 2008 Sep;8(17):3536-47
18686298
Genes Cells. 2005 Oct;10(10):941-51
16164595
Mol Cell Proteomics. 2007 Oct;6(10):1711-26
17586839
Nature. 2007 Mar 8;446(7132):195-8
17293878
Plant Mol Biol. 2008 Mar;66(4):429-43
18185910