Longitudinal associations among depression, obesity and alcohol use disorders in young adulthood.
OBJECTIVE
This study examined concurrent and prospective relations between clinical depression, obesity and alcohol use disorders during young adulthood to better understand common etiology and the progression of co-occurrence.


METHODS
Participants were 776 young adults (393 males and 383 females) who were interviewed at ages 24, 27 and 30 years with assessment of past-year major depressive episode, past-year alcohol abuse or dependence disorder, and obesity. Longitudinal path analyses were conducted separately for women and men, controlling for income and including stability of each of these outcomes.


RESULTS
Among women, depression was positively associated with later alcohol use disorders (ages 27 to 30: OR=3.11), and alcohol use disorders prospectively predicted obesity (ages 24 to 27: OR=3.84). Obesity predicted depression from ages 27 to 30 among women (OR=2.14), but was protective against depression for males (OR=0.31).


CONCLUSIONS
Results show that depression, obesity and alcohol use disorders are interrelated conditions for women. A greater understanding of reasons underlying the co-occurrence of these conditions would benefit prevention and intervention efforts.
McCarty
Carolyn A
CA
Department of Pediatrics, University of Washington, Seattle, WA 98115, USA. cmccarty@u.washington.edu
Kosterman
Rick
R
Mason
W Alex
WA
McCauley
Elizabeth
E
Hawkins
J David
JD
Herrenkohl
Todd I
TI
Lengua
Liliana J
LJ
D000328:Adult; D000437:Alcoholism / Q000453:epidemiology*; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity / Q000453:epidemiology*; D014861:Washington; D055815:Young Adult
Prev Sci. 2005 Mar;6(1):21-33
15766003
J Adolesc Health. 2006 Sep;39(3):305-17
16919791
JAMA. 2004 Jun 16;291(23):2847-50
15199035
Am J Public Health. 1997 Aug;87(8):1303-10
9279265
Aust N Z J Public Health. 2003;27(4):434-40
14705308
J Consult Clin Psychol. 1996 Jun;64(3):552-62
8698949
Alcohol Clin Exp Res. 2007 Jan;31(1):78-88
17207105
Obes Res. 1998 Sep;6 Suppl 2:51S-209S
9813653
Alcohol Clin Exp Res. 1999 Jan;23(1):127-33
10029213
J Psychosom Res. 2002 Oct;53(4):935-42
12377306
Arch Pediatr Adolesc Med. 2003 Aug;157(8):739-45
12912778
Arch Gen Psychiatry. 1997 Apr;54(4):313-21
9107147
Am J Epidemiol. 1997 Dec 1;146(11):966-74
9400339
J Drug Issues. 1996;26(2):429-455
17848978
Int J Obes (Lond). 2006 Mar;30(3):513-9
16302017
Obes Res. 2005 Jan;13(1):101-9
15761168
Can J Psychiatry. 2001 Sep;46(7):632-8
11582825
J Addict Dis. 2004;23(3):105-18
15256347
J Abnorm Psychol. 2007 Feb;116(1):198-207
17324030
J Stud Alcohol. 1999 Mar;60(2):219-27
10091960
J Stud Alcohol. 1997 Sep;58(5):464-73
9273910
Appetite. 2006 Nov;47(3):361-71
16846665
Am J Addict. 1997 Fall;6(4):273-83
9398925
Drug Alcohol Depend. 2001 Aug 1;63(3):277-86
11418232
J Consult Clin Psychol. 2006 Jun;74(3):401-15
16822098
J Abnorm Psychol. 2001 May;110(2):309-23
11358025
Br J Addict. 1991 Oct;86(10):1283-98
1836410
Compr Psychiatry. 1998 Jul-Aug;39(4):176-84
9675501
J Am Acad Child Adolesc Psychiatry. 1990 Jul;29(4):611-9
2387797
Int J Obes Relat Metab Disord. 1998 Jul;22(7):688-94
9705031
Obesity (Silver Spring). 2007 Jan;15(1):197-208
17228048
Arch Gen Psychiatry. 2002 Sep;59(9):794-800
12215078
J Psychosom Res. 1996 Jan;40(1):59-66
8730645
Addict Behav. 2002 Nov-Dec;27(6):867-86
12369473
Arch Pediatr Adolesc Med. 2005 Jan;159(1):25-31
15630054
Drug Alcohol Depend. 1998 Nov 1;52(3):201-9
9839146
JAMA. 2004 Mar 10;291(10):1238-45
15010446
Am J Psychiatry. 2000 May;157(5):751-8
10784468
Arch Pediatr Adolesc Med. 1999 Mar;153(3):226-34
10086398
J Consult Clin Psychol. 1999 Apr;67(2):177-85
10224727
J Am Acad Child Adolesc Psychiatry. 2000 Feb;39(2):223-31
10673834
Harv Rev Psychiatry. 1997 Jan-Feb;4(5):231-44
9385000
Br J Nutr. 2004 Aug;92 Suppl 1:S31-4
15384320
Am J Public Health. 2000 Feb;90(2):251-7
10667187
Drug Alcohol Depend. 2002 Dec 1;68(3):299-307
12393224
J Stud Alcohol. 2004 Mar;65(2):204-12
15151351
Psychol Med. 2004 Aug;34(6):1047-57
15554575
Psychol Med. 2006 Aug;36(8):1153-62
16734951
Int J Obes Relat Metab Disord. 1992 Dec;16(12):999-1003
1335980
Drug Alcohol Rev. 2006 Nov;25(6):515-36
17132571
Ann Behav Med. 2002 Summer;24(3):169-80
12173674
Cochrane Database Syst Rev. 2005 Jul 20;(3):CD001871
16034868
Int J Obes Relat Metab Disord. 2004 Mar;28(3):418-25
14724662
Arch Gen Psychiatry. 2007 Jul;64(7):830-42
17606817
Arch Gen Psychiatry. 2006 Jul;63(7):824-30
16818872
Br Med J. 1976 Jan 3;1(6000):7-9
1247732
J Psychosom Res. 2002 Oct;53(4):891-5
12377299
Int J Obes Relat Metab Disord. 2003 Apr;27(4):514-21
12664085
JAMA. 2003 Jun 18;289(23):3095-105
12813115
Am J Epidemiol. 2000 Jul 15;152(2):163-70
10909953