title: Dysphagia and dysphonia in a patient with cancer.
abstract: A patient with cancer undergoing chemotherapy via Portacath presented with severe progressive dysphagia and dysphonia. Unilateral paresis of the 9, 10, 11, and 12th cranial nerves was found (Collet-Sicard's syndrome or Villaret's syndrome), associated with ipsilateral jugular vein thrombosis identified by imaging. The use of central venous catheters is increasing, and even rare, hitherto unreported, complications need to be recognized. After catheter removal, the patient slowly improved with low-molecular weight heparin treatment and time.
authors.affiliation: Department of Medicine, Kaplan Medical Centre, Rehovot, Israel. amimd@clalit.org.il
authors.forename: Ami
authors.initials: A
authors.lastname: Schattner
authors.forename: Andras
authors.initials: A
authors.lastname: Mate
authors.forename: Gil
authors.initials: G
authors.lastname: Lahav
authors.forename: Meital
authors.initials: M
authors.lastname: Adi
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003110:Colonic Neoplasms / Q000188:drug therapy*; D003389:Cranial Nerve Diseases / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology; D055154:Dysphonia / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007601:Jugular Veins / Q000000981:diagnostic imaging; D008297:Male; D010291:Paresis / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents