title: Cross-cyclotrimerization with two nitriles as a synthetic pathway to unsymmetrically 3,3'-disubstituted bis(tetrahydroisoquinolines).
abstract: Microwave assisted CpCo(CO)(2) catalyzed cross-cyclotrimerizations of 1,7,9,15-hexadecatetrayne with two different nitriles to give unsymmetrically substituted bis(tetrahydroisoquinolines) was studied. The reaction proceeded with a range of alkyl and aryl nitriles with reasonable isolated yields.
authors.affiliation: Department of Organic and Nuclear Chemistry, Center for Structural and Synthetic Application of Transition Metal Complexes, Charles University in Prague, Hlavova 8, 128 43 Praha 2, Czech Republic.
authors.forename: Aneta
authors.initials: A
authors.lastname: Kadlcíková
authors.forename: Martin
authors.initials: M
authors.lastname: Kotora
mesh_terms: D003035:Cobalt / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008872:Microwaves; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D044005:Tetrahydroisoquinolines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D009570:Nitriles; D011725:Pyridines; D044005:Tetrahydroisoquinolines; D003035:Cobalt
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