International Quotidian Dialysis Registry: annual report 2009.
The International Quotidian Dialysis Registry (IQDR) is a global initiative designed to study practices and outcomes associated with the use of hemodialysis regimens of increased frequency and/or duration. Several small studies suggest that compared with conventional hemodialysis (HD), short-daily, nocturnal, and long conventional HD regimens may improve surrogate endpoints and quality of life. However, methodologically robust comparisons on hard outcomes are sorely lacking. The IQDR represents the first-ever attempt to aggregate long-term follow-up data from centers utilizing alternative HD regimens worldwide, and will have adequate statistical power to examine the effects of these regimens on multiple clinical endpoints, including mortality. To date, the IQDR has enrolled patients from Canada, the United States, Australia, and New Zealand, with plans in place to begin linking with additional commercial databases and national registries. This fifth annual report of the IQDR describes (1) a proposed governance structure that will facilitate international collaboration, stakeholder input and funding; (2) data sources and participating registries; (3) recruitment to date and patient baseline characteristics; and (4) an agenda for future research.
Nesrallah
Gihad E
GE
Department of Nephrology, Humber River Regional Hospital, Toronto, ON, Canada.
Suri
Rita S
RS
Moist
Louise M
LM
Cuerden
Meaghan
M
Groeneweg
Karen E
KE
Hakim
Raymond
R
Ofsthun
Norma J
NJ
McDonald
Stephen P
SP
Hawley
Carmel
C
Caskey
Fergus J
FJ
Couchoud
Cecile
C
Awaraji
Christian
C
Lindsay
Robert M
RM
D006801:Humans; D007391:International Cooperation; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000628:therapy*; D012042:Registries; D006435:Renal Dialysis; D016896:Treatment Outcome