title: A three-decade experience of radical open endvenectomy with pericardial patch graft for correction of Budd-Chiari syndrome.
abstract: BACKGROUND
  We previously reported the value of our operative procedure for Budd-Chiari syndrome (BCS) that comprised reconstruction of the occluded or severely stenosed inferior vena cava (IVC) using an autologous pericardium patch and reopening as many occluded hepatic veins as possible. Here, we present the long-term durability and efficacy of the autologous pericardium patch for reconstruction of the IVC in BCS.
  
  
  METHODS
  We retrospectively analyzed a series of 53 consecutive patients (mean age, 48.4 +/- 12.8 years; range, 24-76 years; 34 men) who underwent surgical treatment for BCS at our institution from 1979 to 2008. Patency of the IVC and hepatic veins was examined by venography at discharge. Patients attended an outpatient clinic every 1 or 2 months for follow-up. The reconstructed IVC was evaluated by enhanced computed tomography every 1 or 2 years.
  
  
  RESULTS
  Two in-hospital (operative mortality, 3.7%) and 15 late deaths occurred. During a mean follow-up of 7.6 +/- 6.5 years (range, 0.08-24.1 years), the reconstructed IVC became totally obstructed in three patients, of whom two underwent reoperation, and severely stenosed in two patients, who required percutaneous transvenous balloon venoplasty (PTV). The 5- and 10-year patency rates without reoperation or PTV for the reconstructed IVC were 90.5% and 84.3%, respectively. The cumulative 5- and 10-year survival rates were 89.8% and 70.7%, respectively.
  
  
  CONCLUSIONS
  The autologous pericardium patch is effective and durable for reconstructing a diseased IVC in BCS.
authors.affiliation: Department of Cardiovascular Surgery, Thoracic and Cardiovascular Surgery Division, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan. hitoshiinafuku@yahoo.co.jp
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Inafuku
authors.forename: Yuji
authors.initials: Y
authors.lastname: Morishima
authors.forename: Takaaki
authors.initials: T
authors.lastname: Nagano
authors.forename: Katsuya
authors.initials: K
authors.lastname: Arakaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamashiro
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kuniyoshi
mesh_terms: D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D006503:Hepatic Veins / Q000000981:diagnostic imaging / Q000601:surgery*; D017052:Hospital Mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D010690:Phlebography; D012086:Reoperation; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000601:surgery*; D055815:Young Adult
chemical_list: D000925:Anticoagulants