title: [Acute transverse myelopathy after intramuscular injection of benzathine-benzylpenicillin. Case report in Dakar, Senegal].
abstract: Intramuscular injection of benzathine-benzylpenicillin can cause acute transverse myelopathy. The purpose of this report is to describe a case of acute transverse myelopathy observed after injection of benzathine-benzylpenicillin in a 38-year-old man. The patient who was married and had a history of eczema was admitted to the Department of Neurology of the Fann University Teaching Hospital in 2006. All laboratory findings were normal except high serum immunoglobulin E level. An immunoallergic reaction involving inflammatory transverse myelopathy secondary to vasculitis was proposed as the most likely underlying mechanism. Treatment with corticosteroid and physiotherapy led to a favorable outcome. Health personnel should know the indications for use of benzathine-benzylpenicillin and be aware of the possible medullary complications.
authors.forename: K
authors.initials: K
authors.lastname: Toure
authors.forename: N Y
authors.initials: NY
authors.lastname: Mapoure
authors.forename: N G
authors.initials: NG
authors.lastname: Diagne
authors.forename: Y N
authors.initials: YN
authors.lastname: Faustin
authors.forename: M S
authors.initials: MS
authors.lastname: Diop
authors.forename: L B
authors.initials: LB
authors.lastname: Seck
authors.forename: M
authors.initials: M
authors.lastname: Ndiaye
authors.forename: F
authors.initials: F
authors.lastname: Sene Diouf
authors.forename: A
authors.initials: A
authors.lastname: Thiam
authors.forename: A G
authors.initials: AG
authors.lastname: Diop
authors.forename: M
authors.initials: M
authors.lastname: Diagne
authors.forename: Tal
authors.initials: T
authors.lastname: Diaa
authors.forename: M M
authors.initials: MM
authors.lastname: Ndiaye
mesh_terms: D000328:Adult; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008297:Male; D009187:Myelitis / Q000209:etiology*; D010401:Penicillin G Benzathine / Q000008:administration & dosage* / Q000009:adverse effects* / Q000276:immunology; D012675:Senegal; D014657:Vasculitis / Q000150:complications / Q000276:immunology
chemical_list: D010401:Penicillin G Benzathine