title: Quinones as key intermediates in natural products Synthesis. Syntheses of bioactive xanthones from Hypericum perforatum.
abstract: Two bioactive xanthones from Hypericum perforatum have been synthesized by direct routes. Benzo[c]xanthone 5 can be prepared from intermediate 4.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA. gakraus@iastate.edu
authors.forename: George A
authors.initials: GA
authors.lastname: Kraus
authors.forename: John
authors.initials: J
authors.lastname: Mengwasser
mesh_terms: D002855:Chromatography, Thin Layer; D020902:Hypericum / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011809:Quinones / Q000737:chemistry*; D044004:Xanthones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D011809:Quinones; D044004:Xanthones
references.citation: Synthesis (Stuttg). 2005 Dec;2005(20):3502-3504
references.pmid: 17106483
references.citation: Phytochemistry. 2006 Dec;67(23):2568-72
references.pmid: 17092525
references.citation: Planta Med. 2006 Dec;72(15):1433-5
references.pmid: 17091434
references.citation: Planta Med. 1998 Apr;64(3):281-2
references.pmid: 9581528
references.citation: Neuroscience. 2007 Sep 21;148(4):915-24
references.pmid: 17825492
references.citation: J Org Chem. 2006 Jun 23;71(13):4992-5
references.pmid: 16776532
references.citation: Planta Med. 2005 Apr;71(4):372-5
references.pmid: 15856419