An outbreak of fatal hemorrhagic pneumonia caused by Streptococcus equi subsp. zooepidemicus in shelter dogs.
An outbreak of fatal hemorrhagic pneumonia with 70-90% morbidity and 50% mortality occurred in an animal shelter in Yangju, Gyeonggi Province, Korea. Clinically, the affected dogs showed severe respiratory distress within 48 h after arriving in the shelter. The dead were found mainly with nasal bleeding and hematemesis. At necropsy, hemothorax and hemorrhagic pneumonia along with severe pulmonary consolidation was observed, though histopathological analysis showed mainly hemorrhagic bronchopneumonia. Lymphoid depletion was inconsistently seen in the spleen, tonsil and bronchial lymph node. Gram-positive colonies were shown in blood vessels or parenchyma of cerebrum, lung, liver, spleen, and kidney. Also, Streptococcus (S.) equi subsp. zooepidemicus was isolated from the various organs in which the bacterium was microscopically and histologically detected. In addition, approximately 0.9 Kb specific amplicon, antiphagocytic factor H binding protein, was amplified in the bacterial isolates. In this study, we reported an outbreak of canine hemorrhagic bronchopneumonia caused by S. equi subsp. zooepidemicus in an animal shelter in Yangju, Korea.
Byun
Jae Won
JW
Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service, Anyang 430-824, Korea. jwbyun@nvrqs.go.kr
Yoon
Soon Seek
SS
Woo
Gye-Hyeong
GH
Jung
Byeong Yeal
BY
Joo
Yi-Seok
YS
D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary*; D004283:Dog Diseases / Q000453:epidemiology* / Q000382:microbiology* / Q000473:pathology; D004285:Dogs; D007723:Korea / Q000453:epidemiology; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D018502:Streptococcus equi / Q000302:isolation & purification / Q000502:physiology*
Am J Vet Res. 1998 Sep;59(9):1129-33
9736390
J Vet Med B Infect Dis Vet Public Health. 2004 Dec;51(10):455-8
15606870
J Virol Methods. 2006 Sep;136(1-2):171-6
16750863
J Clin Microbiol. 2006 Jul;44(7):2664-5
16825410
Vet Rec. 2007 Oct 13;161(15):528-30
17938413
Vet Microbiol. 2003 Aug 29;95(1-2):149-56
12860084
Vet Microbiol. 2005 Aug 10;109(1-2):135-41
15953700
J Am Vet Med Assoc. 1982 Dec 1;181(11):1371-4
7174463
Vet Res Commun. 2001 Jan;25(1):77-84
11214675
Vet Microbiol. 2007 Mar 31;121(1-2):105-15
17188435
Vet Pathol. 2008 Jan;45(1):51-3
18192575
Vet Microbiol. 2007 Oct 6;124(3-4):219-29
17531409