PAS/LOV proteins: A proposed new class of plant blue light receptor.
The light, oxygen or voltage (LOV) domain belongs to the Per-ARNT-Sim (PAS) superfamily of domains, and functions with the flavin chromophore as a module for sensing blue light in plants and fungi. The Arabidopsis thaliana PAS/LOV proteins (PLPs), of unknown function, possess an N-terminal PAS domain and a C-terminal LOV domain. Our recent analysis using yeast two-hybrid and Escherichia coli protein production systems reveals that the interactions of Arabidopsis PLPs with several proteins diminish under blue light illumination and that the PLP LOV domain may bind to a flavin chromophore. These results suggest that PLP functions as a blue light receptor. Homologs of PLP exist in rice, tomato and moss. The LOV domains of these PLP homologs form a distinct group in phylogenetic analysis. These facts suggest that PLP belongs to a new class of plant blue light receptor.
Ogura
Yasunobu
Y
Division of Genome Analysis and Genetic Research; Life Science Research Center; Institute of Research Promotion; Kagawa University; Kagawa Japan.
Tokutomi
Satoru
S
Wada
Masamitsu
M
Kiyosue
Tomohiro
T
Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13337-42
16150710
Annu Rev Plant Biol. 2007;58:21-45
17067285
Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4908-12
15781858
Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19625-30
18003911
Plant Physiol. 2002 Jun;129(2):440-50
12068090
Cell. 2000 Apr 28;101(3):331-40
10847687
Proc Natl Acad Sci U S A. 2007 May 29;104(22):9534-9
17485667
Science. 2003 Sep 12;301(5639):1541-4
12970567
Cell. 2000 Apr 28;101(3):319-29
10847686
J Biol Chem. 2007 Jun 29;282(26):18879-85
17462988
Biochemistry. 2003 Jan 14;42(1):2-10
12515534
J Plant Res. 2008 Jan;121(1):97-105
17982713
Science. 2007 Oct 12;318(5848):261-5
17872410
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8779-83
10411952
Genetics. 2000 Feb;154(2):847-56
10655235
Nature. 2007 Sep 20;449(7160):356-60
17704763
Nature. 2003 Nov 20;426(6964):302-6
14628054
Plant J. 2000 Sep;23(6):807-15
10998191
Plant Cell. 2001 Dec;13(12):2659-70
11752379