Low N-acetyltransferase 2 activity in isoniazid-associated acute hepatitis requiring liver transplantation.
Cramer
Jakob P
JP
Lohse
Ansgar W
AW
Burchard
Gerd D
GD
Fischer
Lutz
L
Nashan
Björn
B
Zimmermann
Mathias
M
Marx
Andreas
A
Kluge
Stefan
S
D000995:Antitubercular Agents / Q000009:adverse effects* / Q000493:pharmacokinetics; D001191:Arylamine N-Acetyltransferase / Q000172:deficiency* / Q000235:genetics*; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology* / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D005260:Female; D019450:Genes, MDR; D014644:Genetic Variation; D006579:Heterozygote; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects* / Q000493:pharmacokinetics; D016031:Liver Transplantation; D008875:Middle Aged; D009154:Mutation; D012307:Risk Factors
D000995:Antitubercular Agents; D001191:Arylamine N-Acetyltransferase; C478900:NAT2 protein, human; D007538:Isoniazid