Preoperative cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia: a case report.
BACKGROUND
Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin. To the best of our knowledge, the fine needle aspiration cytologic features of this distinct morphologic entity have not been docnmented before.


METHODS
A 48-year-old male presented with right-sided parotid swelling that was clinically diagnosed as a pleomorphic adenoma. Fine needle aspiration yielded sticky, fatty material; the smears showed features of pleomorphic adenoma with intimately associated, abundant adipose tissue elements. A cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia was rendered and confirmed by histopathologic examination.


CONCLUSIONS
Pleomorphic adenoma with extensive lipometaplasia is an unusual benign salivary gland tumor with distinct histomorphology. Cytologically, it is characterized by the presence of an excessive amount of intimately associated adipose tissue in an otherwise-classic pleomorphic adenoma.
Siddaraju
Neelaiah
N
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. rajusiddaraju@yahoo.com
Singh
Neha
N
Muniraj
Femela
F
Jothilingam
Prabhavati
P
Kumar
Surendra
S
Basu
Debdatta
D
Saxena
Sunil Kumar
SK
D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D000273:Adipose Tissue / Q000473:pathology; D044963:Biopsy, Fine-Needle; D006801:Humans; D008297:Male; D008679:Metaplasia / Q000473:pathology; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery