title: Cutaneous gamma/delta T-cell lymphoma.
abstract: Only 40 cases of primary cutaneous gamma/delta T-cell lymphoma (GD-TCL) have been described. GD-TCL was included as a provisional entity in the WHO-EORTC classification of cutaneous lymphomas in 2005. GD-TCL often failed to respond to polychemotherapy and radiation therapy and have a poor prognosis with a mean survival of only 15 months. We present a patient treated with surgery, immunomodulatory therapy, and polychemotherapy. He then received hematopoietic stem cell transplantation and has been in complete remission since. Allogeneic stem cell transplantation appears to be a promising therapeutic option for aggressive and generally fatal lymphomas like GD-TCL.
authors.affiliation: Eduard-Arning Clinic for Dermatology and Allergology Asklepios Klinik St. Georg, Lohmühlenstraße 5, Hamburg, Germany. ri.koch@asklepios.com
authors.forename: Richard
authors.initials: R
authors.lastname: Koch
authors.forename: Elaine S
authors.initials: ES
authors.lastname: Jaffe
authors.forename: Christian
authors.initials: C
authors.lastname: Mensing
authors.forename: Matthias
authors.initials: M
authors.lastname: Zeis
authors.forename: Norbert
authors.initials: N
authors.lastname: Schmitz
authors.forename: Christian A
authors.initials: CA
authors.lastname: Sander
mesh_terms: D000328:Adult; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000235:genetics / Q000473:pathology* / Q000601:surgery*; D008297:Male; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000235:genetics; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery*; D033581:Stem Cell Transplantation; D016896:Treatment Outcome
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta
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