Pediatric sweet syndrome: case report and literature review.
We report on an 18-month-old boy with a typical presentation of Sweet syndrome following an upper respiratory tract illness. No evidence of hematologic malignancy was found and he was successfully treated with oral prednisolone. A comprehensive literature review has summarized the features of pediatric Sweet syndrome from 66 reported cases. Cases occurring under the age of 3 years had a male predominance and no association with malignancy, whereas cases over the age of 3 years had an equal sex distribution and were strongly associated with myeloid line hematologic malignancies. Identified complications were serious with an overall mortality of 9% rising to 40% with cardiovascular involvement.
Halpern
James
J
Department of Dermatology, University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom. james_halpern@hotmail.com
Salim
Asad
A
D000284:Administration, Oral; D001132:Arm; D004334:Drug Administration Schedule; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007866:Leg; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage*; D012867:Skin / Q000473:pathology*; D016463:Sweet Syndrome / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D016896:Treatment Outcome
D005938:Glucocorticoids; D011239:Prednisolone