Meigs' syndrome and virilizing ovarian fibrothecoma complicating pregnancy. A case report and review of the literature.
BACKGROUND
A half of virilizing ovarian tumors in pregnancy are malignant. The risk of cancer increases with ascites and hydrothorax. Our case shows that such tumor can be benign with good outcome.


METHODS
Primigravida in 30 weeks with advanced hirsutism (from 15 weeks), vomiting, epigastric pain, dyspnoea, ascites, hydrothorax, ovarian mass and high level of serum testosterone was operated. After the tumorectomy (fibrothecoma) we performed cesarean section (placental abruption suspected). The female fetus had no signs of virilization. In mother all symptoms and effusions resolved.


CONCLUSIONS
Meigs' syndrome in pregnancy leads to acute clinical symptoms and needs the surgical intervention with the risk of placental abruption. Virilization of mother was the first symptom of ovarian tumor but the female fetus was protected of hyperandrogenism.
Nowak
Marek
M
Department of Gynecologic Surgery, Polish Mother's Memorial Hospital - Research Institute, Poland. mrn@poczta.onet.pl
Podciechowski
Lech
L
Krawczyk
Tomasz
T
Wilczynski
Jan
J
D002585:Cesarean Section; D005260:Female; D005350:Fibroma / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008539:Meigs Syndrome / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000601:surgery*; D011256:Pregnancy Outcome; D014770:Virilism / Q000209:etiology*; D055815:Young Adult