title: Influence of partner's infection status on prevalent human papillomavirus among persons with a new sex partner.
abstract: BACKGROUND
  We evaluated the influence of the partner's human papillomavirus (HPV) status and sexual practices on prevalent HPV infection among new couples to study HPV transmission.
  
  
  METHODS
  Women attending university or college in Montreal, Canada, and their male partners (N = 263 couples) were enrolled in 2005-2008. HPV typing was done in self-collected vaginal swabs and clinician-collected penis and scrotum swabs. The outcome measures were overall and type-specific HPV prevalence.
  
  
  RESULTS
  HPV was detected in 56% of women and men. Prevalence was higher among persons with infected partners (85%) than in those whose partners were negative (19%). Type-specific detection was substantially higher among women (OR = 55.2, 95% CI: 38.0-80.1) and men (OR = 58.7, 95% CI: 39.8-86.3) if their partner harbored the type under consideration. Prevalence among women and men with 10 or more lifetime partners was 15.4 (95% CI: 5.9-40.2) and 9.5 (95% CI: 4.4-19.8) times higher than among those with 1 partner. Frequent condom use was protective in men, particularly if his partner was HPV-infected (OR = 0.64, 95% CI: 0.50-0.82). This effect was attenuated among women with an infected partner (OR = 0.88, 95% CI: 0.69-1.11).
  
  
  CONCLUSIONS
  The current partner's status was the most important risk factor for prevalent HPV infection. Condoms exerted a stronger protective effect among men than among women.
authors.affiliation: Department of Oncology, McGill University, Montreal, Quebec, Canada.
authors.forename: Ann N
authors.initials: AN
authors.lastname: Burchell
authors.forename: Pierre-Paul
authors.initials: PP
authors.lastname: Tellier
authors.forename: James
authors.initials: J
authors.lastname: Hanley
authors.forename: François
authors.initials: F
authors.lastname: Coutlée
authors.forename: Eduardo L
authors.initials: EL
authors.lastname: Franco
mesh_terms: D000293:Adolescent; D000328:Adult; D052685:Alphapapillomavirus / Q000145:classification; D017280:Condoms; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission*; D015995:Prevalence; D011792:Quebec / Q000453:epidemiology; D021841:Safe Sex; D012747:Sexual Partners; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission*
references.citation: JAMA. 2000 Jan 5;283(1):81-6
references.pmid: 10632284
references.citation: J Infect Dis. 2002 Aug 15;186(4):462-9
references.pmid: 12195372
references.citation: JAMA. 2007 Feb 28;297(8):813-9
references.pmid: 17327523
references.citation: Sex Transm Dis. 2009 Apr;36(4):261-3
references.pmid: 19077921
references.citation: Am J Epidemiol. 2001 Apr 15;153(8):740-8
references.pmid: 11296145
references.citation: J Infect Dis. 2006 Oct 15;194(8):1044-57
references.pmid: 16991079
references.citation: CMAJ. 2000 Sep 5;163(5):513-8
references.pmid: 11006761
references.citation: Sex Transm Dis. 2002 Jun;29(6):344-9
references.pmid: 12035024
references.citation: Sex Transm Dis. 2002 Sep;29(9):530-2
references.pmid: 12218844
references.citation: Sex Transm Dis. 2004 Oct;31(10):601-7
references.pmid: 15388997
references.citation: Am J Epidemiol. 2003 Feb 1;157(3):218-26
references.pmid: 12543621
references.citation: J Infect Dis. 2004 Feb 15;189(4):677-85
references.pmid: 14767822
references.citation: J Clin Microbiol. 2006 Jun;44(6):1998-2006
references.pmid: 16757590
references.citation: Int J Cancer. 2006 Oct 15;119(8):1934-9
references.pmid: 16708372
references.citation: J Infect Dis. 2007 Oct 15;196(8):1128-36
references.pmid: 17955430
references.citation: Am J Epidemiol. 2004 Feb 1;159(3):242-51
references.pmid: 14742284
references.citation: N Engl J Med. 2006 Jun 22;354(25):2645-54
references.pmid: 16790697
references.citation: Am J Epidemiol. 2006 Feb 1;163(3):197-203
references.pmid: 16339049
references.citation: Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2036-43
references.pmid: 18708396
references.citation: Vaccine. 2008 Aug 19;26 Suppl 10:K17-28
references.pmid: 18847554
references.citation: N Engl J Med. 2002 Apr 11;346(15):1105-12
references.pmid: 11948269
references.citation: Am J Epidemiol. 2006 Mar 15;163(6):534-43
references.pmid: 16421235
references.citation: Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1107-14
references.pmid: 17548671
references.citation: J Epidemiol Biostat. 2001;6(5):393-407
references.pmid: 11822729
references.citation: JAMA. 2001 Jun 20;285(23):2995-3002
references.pmid: 11410098
references.citation: Sex Transm Infect. 1999 Oct;75(5):317-9
references.pmid: 10616355
references.citation: J Infect Dis. 1997 Aug;176(2):353-61
references.pmid: 9237700
references.citation: N Engl J Med. 1998 Feb 12;338(7):423-8
references.pmid: 9459645
references.citation: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1710-6
references.pmid: 16030106
references.citation: Emerg Infect Dis. 2008 Jun;14(6):888-94
references.pmid: 18507898
references.citation: N Engl J Med. 2003 Feb 6;348(6):518-27
references.pmid: 12571259
references.citation: Sex Transm Dis. 2002 Nov;29(11):725-35
references.pmid: 12438912
references.citation: Cancer Epidemiol Biomarkers Prev. 2000 May;9(5):469-76
references.pmid: 10815691
references.citation: Br J Cancer. 2002 Mar 4;86(5):705-11
references.pmid: 11875730
references.citation: JAMA. 1991 Jan 23-30;265(4):472-7
references.pmid: 1845912
references.citation: Cancer Epidemiol Biomarkers Prev. 2003 Jun;12(6):485-90
references.pmid: 12814991
references.citation: Cancer Epidemiol Biomarkers Prev. 2001 Feb;10(2):95-100
references.pmid: 11219778
references.citation: J Infect Dis. 2009 Feb 1;199(3):362-71
references.pmid: 19133808
references.citation: J Infect Dis. 2008 Mar 15;197(6):787-94
references.pmid: 18284369
references.citation: Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1528-33
references.pmid: 15941967
references.citation: J Infect Dis. 2008 Jan 15;197(2):279-82
references.pmid: 18179386
references.citation: J Infect Dis. 2004 Dec 15;190(12):2077-87
references.pmid: 15551205
references.citation: Int J Cancer. 2003 Dec 10;107(5):804-10
references.pmid: 14566831
references.citation: J Infect Dis. 2007 Oct 15;196(8):1137-45
references.pmid: 17955431