Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range.
We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber angle and the cornea. The speed of 200,000 lines/s enables high sampling density in three-dimensional imaging of the entire cornea in 250 ms promising future applications of OCT for optical corneal topography, pachymetry and elevation maps. The results of a preliminary quantitative corneal analysis based on OCT data free form motion artifacts are presented. Additionally, a volumetric and real time reconstruction of dynamic processes, like pupillary reaction to light stimulus or blink-induced contact lens movements are demonstrated.
Gora
Michalina
M
Institute of Physics, Nicolaus Copernicus University, ul. Grudziadzka 5/7, PL-87-100 Toruń, Poland.
Karnowski
Karol
K
Szkulmowski
Maciej
M
Kaluzny
Bartlomiej J
BJ
Huber
Robert
R
Kowalczyk
Andrzej
A
Wojtkowski
Maciej
M
D016477:Artifacts; D003315:Cornea / Q000033:anatomy & histology; D019781:Corneal Topography / Q000379:methods; D003952:Diagnostic Imaging / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D005123:Eye / Q000033:anatomy & histology* / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis* / Q000473:pathology; D005583:Fourier Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D007834:Lasers; D009038:Motion; D009885:Ophthalmology / Q000379:methods; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods