Variants weakly correlated with CHRNA5 D398N polymorphism should be considered in transcriptional deregulation at the 15q25 locus associated with lung cancer risk.
Wang
Jen C
JC
Bierut
Laura J
LJ
Goate
Alison M
AM
D000230:Adenocarcinoma / Q000235:genetics*; D000483:Alleles; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic; D006720:Homozygote; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics*; D009419:Nerve Tissue Proteins / Q000235:genetics*; D011110:Polymorphism, Genetic; D012333:RNA, Messenger / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000235:genetics*; D015854:Up-Regulation / Q000235:genetics / Q000502:physiology
C447158:CHRNA5 protein, human; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger; D011978:Receptors, Nicotinic