Decreased bone mineral density of femur in patients with cervical cancer.
OBJECTIVE
We compared the bone mineral density (BMD) of spinal bone and the femur between patients with cervical cancer and a control group.


METHODS
We retrospectively analyzed the BMD of spinal bone and the femur in 40 patients with cervical cancer and 72 control women. The control women were patients treated with surgery for benign disease.


RESULTS
Age, height, bodyweight and body mass index were not significantly different between the two groups. Total femoral BMD in patients with cervical cancer was significantly lower (P = 0.006) than that of control women. In multiple regression analysis, the bodyweight of patients with cervical cancer was a statistically significant predictor positively correlated with the BMD of the total femur.


CONCLUSIONS
The results suggest that patients with cervical cancer have low bone mass, especially in the femur, and an increased risk of developing osteoporosis.
Lee
Seung H
SH
Department of Obstetrics and Gynecology, Gachon University Gil Medical Center, Incheon, South Korea.
Ku
Chun H
CH
Lee
Kwang B
KB
Shin
Jin W
JW
Park
Chan Y
CY
D000368:Aged; D015519:Bone Density; D005260:Female; D005269:Femur / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000209:etiology; D012044:Regression Analysis; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000503:physiopathology*