Transcallosal connectivity and cortical rhythms: findings in children with spina bifida.
We studied the relation between cortical oscillatory rhythms and the structural integrity of the corpus callosum in 21 children with spina bifida and hydrocephalus. Participants underwent resting state neuromagnetic recordings and diffusion tensor imaging. Areas of three segments of the corpus callosum (genu, body, splenium) were derived through diffusion tensor imaging-based morphometrics. Children with spina bifida showed reduced values of spectral power in the theta, alpha and beta bands when compared with age-matched controls, but only in the posterior and temporal regions. Reduced spectral power in posterior regions correlated with decreased area of the posterior segments of the corpus callosum. Atypical cortical oscillatory activity is associated with reduced transcallosal connectivity in children with spina bifida.
Castillo
Eduardo M
EM
Center for Clinical Neurosciences, Department of Pediatrics, Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA. Eduardo.m.castillo@uth.tmc.edu
Fletcher
Jack M
JM
Li
Zhimin
Z
Hoskison
Mayre M
MM
Hasan
Khader M
KM
Passaro
Anthony
A
Papanicolaou
Andrew C
AC
D000513:Alpha Rhythm; D000704:Analysis of Variance; D001611:Beta Rhythm; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D003337:Corpus Callosum / Q000473:pathology* / Q000503:physiopathology*; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D006849:Hydrocephalus / Q000503:physiopathology*; D015225:Magnetoencephalography; D010507:Periodicity; D012146:Rest; D016135:Spinal Dysraphism / Q000473:pathology / Q000503:physiopathology*; D013826:Theta Rhythm
J Int Neuropsychol Soc. 2000 Mar;6(3):351-61
10824507
Neurology. 2005 Dec 27;65(12):1873-87
16192428
J Int Neuropsychol Soc. 2006 Mar;12(2):285-96
16573862
J Int Neuropsychol Soc. 2008 Sep;14(5):771-81
18764972
J Neurosurg. 2005 Apr;102(3 Suppl):268-79
15881750
Clin Neurophysiol. 2003 Oct;114(10):1936-47
14499756
Neuropsychologia. 2005;43(14):2000-10
15893777
J Clin Exp Neuropsychol. 1999 Dec;21(6):837-50
10649538
Brain Lang. 2005 Jun;93(3):349-68
15862859
Electroencephalogr Clin Neurophysiol. 1977 Sep;43(3):346-61
70336
Neuropsychologia. 1971 Mar;9(1):97-113
5146491
Arch Ital Biol. 1972 Oct;110(3):383-411
4349191
Neuroimage. 2005 Oct 15;28(1):72-83
16023869
J Magn Reson Imaging. 2008 Apr;27(4):700-9
18302204
Psychopharmacol Bull. 1998;34(1):101-5
9580382
Neuroimage. 2008 May 1;40(4):1516-22
18337124
Int Rev Neurobiol. 2005;68:173-95
16443014
Alzheimer Dis Assoc Disord. 2006 Jul-Sep;20(3):153-9
16917185
J Magn Reson Imaging. 2005 Jun;21(6):735-43
15906348