Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing.
We evaluated the ability of direct fluorescent antigen (DFA) influenza tests to identify novel H1N1 influenza virus. DFA results were compared with polymerase chain reaction results. The negative predictive value of DFA testing was at least 96%. Therefore, when performed on specimens of adequate quality, DFA tests can effectively rule out infection due to novel H1N1 virus.
Pollock
Nira R
NR
Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. npollock@bidmc.harvard.edu
Duong
Scott
S
Cheng
Annie
A
Han
Linda L
LL
Smole
Sandra
S
Kirby
James E
JE
D000956:Antigens, Viral / Q000032:analysis*; D019085:Fluorescent Antibody Technique, Direct / Q000592:standards*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
D000956:Antigens, Viral
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