Perioperative management of a child with von Willebrand disease undergoing surgical repair of craniosynostosis: looking at unusual targets.
We report the successful management of a craniosynostosis repair in a child with severe Type I von Willebrand disease diagnosed during the preoperative assessment and treated by coagulation factor VIII and ristocetin cofactor. Collaboration among the anesthesiologist, the neurosurgeon, the clinical pathologist, and the pediatric hematologist is important for successful management.
Maquoi
Isabelle
I
University Department of Anesthesia and ICM, CHR Citadelle, Liege, Belgium.
Bonhomme
Vincent
V
Born
Jacques Daniel
JD
Dresse
Marie-Françoise
MF
Ronge-Collard
Elisabeth
E
Minon
Jean-Marc
JM
Hans
Pol
P
D000244:Adenosine Diphosphate / Q000378:metabolism; D000776:Anesthesiology / Q000379:methods; D003094:Collagen / Q000378:metabolism; D003398:Craniosynostoses / Q000150:complications* / Q000601:surgery*; D004837:Epinephrine / Q000378:metabolism; D006487:Hemostasis; D006801:Humans; D007223:Infant; D008297:Male; D011184:Postoperative Period; D013514:Surgical Procedures, Operative / Q000379:methods; D016896:Treatment Outcome; D014842:von Willebrand Diseases / Q000150:complications* / Q000628:therapy*
D000244:Adenosine Diphosphate; D003094:Collagen; D004837:Epinephrine