[The evaluation of Identifiler system in paternity testing].
OBJECTIVE
To evaluate the power of Identifiler System for paternity testing.


METHODS
A total of 3 277 paternity testing cases were studied using Identifiler System. The exclusion power and mutation rates of the Identifiler System were analysed in the paternity testing.


RESULTS
The cumulated power of exclusion was 0.999 998 827, and the cumulated discriminating power was 0.999 999 999 999 999 98, respectively. Of the 3 277 cases, paternity was confirmed in 2 863, but excluded in 347. Among this paternity testing, mutations involving a single STR locus were observed in 65 cases, while mutations involving 2 STR loci were observed in 2 cases.


CONCLUSIONS
The Identifiler System is powerful and reliable for paternity testing.
Que
Ting-Zhi
TZ
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, PR China. quetz@ssfjd.cn
Yan
Pin-Hua
PH
Lin
Yuan
Y
Liu
Yan
Y
Li
Li
L
D000483:Alleles; D002681:China; D016172:DNA Fingerprinting / Q000379:methods*; D053803:Forensic Genetics / Q000379:methods*; D005820:Genetic Testing / Q000379:methods; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D009154:Mutation; D010334:Paternity; D016133:Polymerase Chain Reaction / Q000379:methods; D011336:Probability; D020080:Tandem Repeat Sequences / Q000235:genetics*