title: [Phylogenetic analysis of the neuraminidase genes of subtype N1 viruses in domestic ducks in eastern China].
abstract: To examine the phylogenetic information regarding the gene pool of AIV in domestic ducks in eastern China, the NA genes of twenty-six viruses isolated during 2002-2006, including two H1N1 strains, tenH3N1 strains and fourteen HSN1 strains, which reflected the predominant N1 subtype viruses were subjected to phylogenetic analysis. The results indicated that AIVs of N1 subtype circulating in domestic ducks in eastern China were undergoing a gradual evolution. Analysis of the deduced amino acid sequences revealed that NAs from all isolated H5N1 viruses had a 20-aa deletion in the stalk region (residues 49-68), whereas no deletion was seen in the NAs from other HA subtype viruses. The viruses of H3N1 and H1N1 might have a propensity for reassortment of NA genes, whereas no direct evidence of reassortment of NA gene was obtained in H5N1 viruses.
authors.affiliation: Key Laboratory of Animal Infectious Diseases of Ministry of Agriculture, Yangzhou University, Yangzhou, China. baofengqiu2008@yahoo.cn
authors.forename: Bao-Feng
authors.initials: BF
authors.lastname: Qiu
authors.forename: Wu-Jie
authors.initials: WJ
authors.lastname: Liu
authors.forename: Ying-Hua
authors.initials: YH
authors.lastname: Tang
authors.forename: Da-Xin
authors.initials: DX
authors.lastname: Peng
authors.forename: Xiu-Fan
authors.initials: XF
authors.lastname: Liu
mesh_terms: D000818:Animals; D001717:Birds; D002681:China; D004279:DNA, Viral / Q000032:analysis; D019143:Evolution, Molecular; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification* / Q000235:genetics; D053122:Influenza A Virus, H3N2 Subtype / Q000145:classification* / Q000235:genetics; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification* / Q000201:enzymology / Q000235:genetics; D009980:Influenza A virus / Q000145:classification* / Q000201:enzymology / Q000235:genetics; D005585:Influenza in Birds / Q000821:virology; D007251:Influenza, Human / Q000821:virology; D009439:Neuraminidase / Q000235:genetics*; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology; D016415:Sequence Alignment; D017384:Sequence Deletion
chemical_list: D004279:DNA, Viral; D009439:Neuraminidase