title: [Genetic relationships between Tuva population and the neighboring populations in the Altai Region of Xinjiang Uygur Autonomous Region].
abstract: In the Hanasi scenic spot of the Altai Region, Xinjiang Uygur Autonomous Region, China, there is a special population known as Xinjiang Tuvinians for short. These Tuvinians were classified as Mongolians in the early 1950s by the National Ethnic Affairs Commission of China, but they claimed that they have an independent origin. To resolve this dispute and their genetic relationships with the people in the neighboring regions, we randomly selected 150 male Tuvinians in the Altai Region. Fourteen Y chromosomal markers were genotyped and eleven haplogroups were constructed. The frequencies of the haplogroups K-M9 and Q-M242 were higher in Xinjiang Tuvinians or Tuvinians in the Tuva Republic than those in the other populations (e.g., Mongolians and Kazakh). Principal component analysis , multi-dimensional scaling analysis and further phylogenetic tree analysis revealed that the Xinjiang Tuvinians were far separated from Mongolians and Kazakh. Based on these results, we proposed that Xinjiang Tuvinians are genetically distinct from Mongolians and Kazakh.
authors.affiliation: Department of Medical Genetics, Zhongshan Medical College, Sun Yat-Sen University, Guangzhou 510080, China. yongkeezhang@hotmail.com
authors.forename: Yong-Ke
authors.initials: YK
authors.lastname: Zhang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Chen
authors.forename: An
authors.initials: A
authors.lastname: Fan
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Zhang
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Wu
authors.forename: Qian-Jun
authors.initials: QJ
authors.lastname: Zhao
authors.forename: Can-Lin
authors.initials: CL
authors.lastname: Zhou
authors.forename: Xin-Min
authors.initials: XM
authors.lastname: Mao
authors.forename: Yu-Liang
authors.initials: YL
authors.lastname: Zang
authors.forename: Yerhaz
authors.initials: Y
authors.lastname: Zarhumar
authors.forename: Hasenbek
authors.initials: H
authors.lastname: Malik
authors.forename: Habudely
authors.initials: H
authors.lastname: Dalabay
authors.forename: Kamaliya
authors.initials: K
authors.lastname: Tuotahaz
authors.forename: Ling
authors.initials: L
authors.lastname: Liang
authors.forename: Gulinur
authors.initials: G
authors.lastname: Yerken
authors.forename: Yue-Hui
authors.initials: YH
authors.lastname: Ma
authors.forename: Shao-Qi
authors.initials: SQ
authors.lastname: Rao
mesh_terms: D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D008297:Male; D010802:Phylogeny; D044469:Racial Groups / Q000145:classification / Q000208:ethnology / Q000235:genetics*