title: Animal models for autoimmune bullous dermatoses.
abstract: Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.
authors.affiliation: Institute of Anatomy, University of Lübeck, Lübeck, Germany.
authors.forename: Katja
authors.initials: K
authors.lastname: Bieber
authors.forename: Shijie
authors.initials: S
authors.lastname: Sun
authors.forename: Norito
authors.initials: N
authors.lastname: Ishii
authors.forename: Michael
authors.initials: M
authors.lastname: Kasperkiewicz
authors.forename: Enno
authors.initials: E
authors.lastname: Schmidt
authors.forename: Misa
authors.initials: M
authors.lastname: Hirose
authors.forename: Jürgen
authors.initials: J
authors.lastname: Westermann
authors.forename: Xinhua
authors.initials: X
authors.lastname: Yu
authors.forename: Detlef
authors.initials: D
authors.lastname: Zillikens
authors.forename: Ralf J
authors.initials: RJ
authors.lastname: Ludwig
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases; D004195:Disease Models, Animal; D007116:Immunization, Passive; D012872:Skin Diseases, Vesiculobullous