title: Iron status in pregnant women in the Republic of Seychelles.
abstract: OBJECTIVE
  To establish the Fe status of pregnant women and their neonates in the Republic of Seychelles.
  
  
  METHODS
  A prospective study.
  
  
  METHODS
  Republic of Seychelles.
  
  
  METHODS
  Pregnant women were recruited and blood samples taken at enrolment and post-delivery along with cord blood samples. Ferritin and soluble transferrin receptor (sTfR) were measured in maternal (n 220) and cord blood (n 123) samples.
  
  
  RESULTS
  Maternal Fe deficiency (ferritin < 15 ng/ml, sTfR > 28 nmol/l) was present in 6 % of subjects at enrolment and in 20 % at delivery. There was no significant decrease in maternal ferritin. A significant increase in sTfR was observed between enrolment and delivery (P < 0.001). Maternal BMI and use of Fe supplements at 28 weeks' gestation were associated with improved maternal Fe status at delivery, whereas parity had a negative effect on sTfR and ferritin at delivery.
  
  
  CONCLUSIONS
  Fe status of pregnant Seychellois women was, on average, within normal ranges. The incidence of Fe deficiency throughout pregnancy in this population was similar to that in a Westernised population. Increased awareness of the importance of adequate Fe intake during pregnancy, particularly in multiparous women, is warranted.
authors.affiliation: Northern Ireland Centre for Food and Health (NICHE), School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK. em.duffy@ulster.ac.uk
authors.forename: Emeir M
authors.initials: EM
authors.lastname: Duffy
authors.forename: Maxine P
authors.initials: MP
authors.lastname: Bonham
authors.forename: Julie M W
authors.initials: JM
authors.lastname: Wallace
authors.forename: Chin-Kuo
authors.initials: CK
authors.lastname: Chang
authors.forename: Paula J
authors.initials: PJ
authors.lastname: Robson
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Myers
authors.forename: Philip W
authors.initials: PW
authors.lastname: Davidson
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Clarkson
authors.forename: Conrad F
authors.initials: CF
authors.lastname: Shamlaye
authors.forename: J J
authors.initials: JJ
authors.lastname: Strain
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000453:epidemiology; D005260:Female; D005293:Ferritins / Q000097:blood; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D007501:Iron / Q000097:blood*; D000090463:Iron Deficiencies; D008297:Male; D009752:Nutritional Status; D010298:Parity; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000453:epidemiology; D011256:Pregnancy Outcome; D015995:Prevalence; D011446:Prospective Studies; D011644:Puerperal Disorders / Q000097:blood / Q000453:epidemiology; D011990:Receptors, Transferrin / Q000032:analysis; D012750:Seychelles / Q000453:epidemiology
chemical_list: D011990:Receptors, Transferrin; D005293:Ferritins; D007501:Iron
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