Susceptibility to infectious diseases based on antimicrobial peptide production.
In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.
Rivas-Santiago
Bruno
B
Unidad de Investigación Médica-Zacatecas, IMSS, Interior de la Alameda #45, Zacatecas, Zacatecas, Mexico.
Serrano
Carmen J
CJ
Enciso-Moreno
J Antonio
JA
D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000235:genetics* / Q000276:immunology*; D003141:Communicable Diseases / Q000235:genetics* / Q000276:immunology*; D020022:Genetic Predisposition to Disease; D006801:Humans
D023181:Antimicrobial Cationic Peptides
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