Regulation and functional specialization of small RNA-target nodes during plant development.
The expansion of gene families for miRNA and tasiRNA, small RNA effector proteins (ARGONAUTEs or AGOs), and miRNA/tasiRNA targets has contributed to regulatory diversity in plants. Loss or acquisition of small RNA-generating loci and target site sequences in multigene families represent striking examples of subfunctionalization or neo-functionalization, where regulatory diversity is achieved at the post-transcriptional level. Differential regulation of small RNA and target gene family members, and evolution of unique functionality of distinct small RNA-AGO complexes, provide further regulatory diversity. Here, we focus on the idea of distinct small RNA-target transcript pairs as nodes within biological networks, and review progress toward understanding the role of small RNA-target nodes in the context of auxin signaling.
Rubio-Somoza
Ignacio
I
Department of Molecular Biology, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany.
Cuperus
Joshua T
JT
Weigel
Detlef
D
Carrington
James C
JC
D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism; D035683:MicroRNAs / Q000378:metabolism*; D005810:Multigene Family; D010944:Plants / Q000235:genetics* / Q000378:metabolism; D018749:RNA, Plant / Q000378:metabolism; D034741:RNA, Small Interfering / Q000378:metabolism*; D014158:Transcription, Genetic
D007210:Indoleacetic Acids; D035683:MicroRNAs; D018749:RNA, Plant; D034741:RNA, Small Interfering