title: Fighting tuberculosis: old drugs, new formulations.
abstract: This review reports the state of the art on innovative drug delivery strategies designed for antitubercular chemotherapeutics. The introduction contains the fundamental biological background concerning tuberculosis and a review of the current antitubercular therapy, and is followed by a critical report of the micrometric and nanometric particulate systems designed and investigated to improve tuberculosis chemotherapy.
authors.affiliation: University of Perugia, School of Pharmacy, Department of Chemistry and Technology of Drugs, Perugia, Italy. kaolino@unipg.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Blasi
authors.forename: Aurélie
authors.initials: A
authors.lastname: Schoubben
authors.forename: Stefano
authors.initials: S
authors.lastname: Giovagnoli
authors.forename: Carlo
authors.initials: C
authors.lastname: Rossi
authors.forename: Maurizio
authors.initials: M
authors.lastname: Ricci
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D016503:Drug Delivery Systems; D006801:Humans; D008863:Microspheres; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification; D054118:Nanospheres; D014376:Tuberculosis / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents