title: Maintaining immune homeostasis in fly gut.
abstract: Like every metazoan species hosting a gut flora, drosophila tolerate commensal microbiota yet remain able to mount an efficient immune response to food-borne pathogens. New findings explain how the quantity of reactive oxygen species in the gut is 'tuned' to microbial burden and how intestinal immune homeostasis is thereby maintained
authors.forename: François
authors.initials: F
authors.lastname: Leulier
authors.forename: Julien
authors.initials: J
authors.lastname: Royet
mesh_terms: D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000096:biosynthesis; D029721:Drosophila Proteins / Q000502:physiology; D004331:Drosophila melanogaster / Q000276:immunology*; D054642:Dual Specificity Phosphatase 6 / Q000502:physiology; D006706:Homeostasis; D007113:Immunity, Innate; D007422:Intestines / Q000276:immunology / Q000382:microbiology; D019255:NADPH Oxidases / Q000502:physiology; D054799:Phospholipase C beta / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D048051:p38 Mitogen-Activated Protein Kinases / Q000502:physiology
chemical_list: D023181:Antimicrobial Cationic Peptides; D029721:Drosophila Proteins; D017382:Reactive Oxygen Species; C505384:dual oxidase, Drosophila; D019255:NADPH Oxidases; D048051:p38 Mitogen-Activated Protein Kinases; D054642:Dual Specificity Phosphatase 6; C486844:Mkp3 protein, Drosophila; D054799:Phospholipase C beta
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