Associated analysis of single nucleotide polymorphisms of IGF2 gene's exon 8 with growth traits in Wuzhishan pig.
A new SNP located in IGF-2 gene of Wuzhishan pig was detected while a C --> T silent mutation at position 17 of exon 8 was detected by Single-Strand Conformational Polymorphism (SSCP). The value of polymorphism information content (PIC) indicated that this locus had intermediate polymorphism information content (0.25 < PIC < 0.5). The results of the fitness of Hardy-Weinberg equilibrium was in disequilibrium (P < 0.01). SAS analysis together with the multiple comparisons between polymorphisms and growth traits showed that: the differences of carcass weight (P = 0.024), withers height (P = 0.037) and chest girth (P = 0.025) in 10-month-old generation group were very remarkable.
Hou
Guanyu
G
Tropical Crops Genetic Resources Institute, CATAS, Hainan, China.
Wang
Dongjin
D
Guan
Song
S
Zeng
Hongpu
H
Huang
Xianzhou
X
Ma
Yuehui
Y
D000818:Animals; D001483:Base Sequence; D004587:Electrophoresis, Agar Gel; D005091:Exons / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D005838:Genotype; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D019655:Quantitative Trait, Heritable; D034421:Sus scrofa / Q000235:genetics* / Q000254:growth & development*
D007335:Insulin-Like Growth Factor II
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