title: A case of S-100-positive juvenile xanthogranuloma: a longitudinal observation.
abstract: We present the case of a 9-month-old boy with yellow-brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S-100-positive juvenile xanthogranuloma, and longitudinal observation revealed that strong S-100 reactivity disappeared in parallel with maturation of the lesions within 2 years after the initial diagnosis. These findings add to the complexity in cells of origin of this disorder.
authors.affiliation: Department of Dermatology, Toyooka Hospital, Tobera, Toyooka, Hyogo, Japan. yamamotoy2@gmail.com
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kadota
authors.forename: Youichi
authors.initials: Y
authors.lastname: Nishimura
mesh_terms: D000375:Aging / Q000378:metabolism; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D012075:Remission, Spontaneous; D009418:S100 Proteins / Q000378:metabolism*; D014972:Xanthogranuloma, Juvenile / Q000378:metabolism* / Q000473:pathology*
chemical_list: D009418:S100 Proteins