Relapsing polychondritis: new therapeutic strategies with biological agents.
Relapsing polychondritis (RP) is a rare disease of unknown etiology characterized by recurrent episodes of inflammation resulting in the destruction of cartilaginous tissues. We describe a young girl with RP unresponsive to conventional therapy.
Buonuomo
Paola Sabrina
PS
Department of Pediatrics, Pediatric Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio, 4, 00135, Rome, Italy. psabrina.buonuomo@opbg.net
Bracaglia
Claudia
C
Campana
Andrea
A
El Hachem
Maya
M
Diociaiuti
Andrea
A
Insalaco
Antonella
A
De Benedetti
Fabrizio
F
Testa
Beatrice Chiarini
BC
Cortis
Elisabetta
E
De Vincentiis
Giovanni Carlo
GC
Ugazio
Alberto G
AG
D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D000069285:Infliximab; D053590:Interleukin 1 Receptor Antagonist Protein / Q000627:therapeutic use*; D007442:Intubation, Intratracheal; D011081:Polychondritis, Relapsing / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D020551:Pulse Therapy, Drug; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000628:therapy; D013256:Steroids / Q000008:administration & dosage; D014139:Tracheostomy; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D053590:Interleukin 1 Receptor Antagonist Protein; D013256:Steroids; D000069285:Infliximab
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