title: Synthesis of functionalized Morita-Baylis-Hillman adducts by a conjugate addition-elimination sequence.
abstract: We have developed a new conjugate addition-elimination sequence for the diastereoselective synthesis of protected allylic syn 1,3-diols which are Morita-Baylis-Hillman adducts. The synthesis of the substrates involves a challenging cross-metathesis reaction that leads to hindered trisubstituted olefins.
authors.affiliation: Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, DCSO, F-91128 Palaiseau, France.
authors.forename: Rémi
authors.initials: R
authors.lastname: Aouzal
authors.forename: Joëlle
authors.initials: J
authors.lastname: Prunet