title: What's new about osmotic regulation of glycerophosphocholine.
abstract: Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.
authors.affiliation: Department of Health and Human Services, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Morgan
authors.initials: M
authors.lastname: Gallazzini
authors.forename: Maurice B
authors.initials: MB
authors.lastname: Burg
mesh_terms: D000818:Animals; D005997:Glycerylphosphorylcholine / Q000502:physiology*; D006801:Humans; D007679:Kidney Medulla / Q000166:cytology / Q000502:physiology*; D012965:Sodium Chloride / Q000378:metabolism; D014508:Urea / Q000378:metabolism; D014882:Water-Electrolyte Balance / Q000502:physiology*
chemical_list: D012965:Sodium Chloride; D005997:Glycerylphosphorylcholine; D014508:Urea
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