Effective photoreduction of a Pt(IV) complex with quantum dots: a feasible new light-induced method of releasing anticancer Pt(II) drugs.
Irradiation of CdSe-ZnS quantum dots (QDs) with visible light in the presence of [PtCl(4)(bpy)] (1) (bpy = 2,2'-bipyridine) produced with high efficiency [PtCl(2)(bpy)] (2) by photoinduced electron transfer; a reaction and strategy which opens up new opportunities for cancer therapy.
Blanco
Nina Gomez
NG
School of Chemistry, University of Edinburgh, EH9 3JJ, Edinburgh, UK.
Maldonado
Carmen R
CR
Mareque-Rivas
Juan C
JC
D015082:2,2'-Dipyridyl / Q000737:chemistry; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry* / Q000528:radiation effects; D019187:Cadmium Compounds / Q000737:chemistry; D004579:Electron Transport; D008027:Light; D009369:Neoplasms / Q000628:therapy; D009944:Organoplatinum Compounds / Q000737:chemistry*; D010778:Photochemotherapy; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry; D013440:Sulfides / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
D000970:Antineoplastic Agents; D019187:Cadmium Compounds; D009944:Organoplatinum Compounds; D018036:Selenium Compounds; D013440:Sulfides; D017967:Zinc Compounds; D015082:2,2'-Dipyridyl; C058667:cadmium selenide; C031238:zinc sulfide