title: WNTs tune up the neuromuscular junction.
abstract: Although WNTs have been long thought of as regulators of cell fate, recent studies highlight their involvement in crucial aspects of synaptic development in the nervous system. Particularly compelling are recent studies of the neuromuscular junction in nematodes, insects, fish and mammals. These studies place WNTs as major determinants of synapse differentiation and neurotransmitter receptor clustering.
authors.affiliation: Department of Neurobiology, Aaron Lazare Biomedical Research Building, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
authors.forename: Ceren
authors.initials: C
authors.lastname: Korkut
authors.forename: Vivian
authors.initials: V
authors.lastname: Budnik
mesh_terms: D000818:Animals; D006801:Humans; D009469:Neuromuscular Junction / Q000737:chemistry / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D013569:Synapses / Q000737:chemistry / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology; D051153:Wnt Proteins / Q000737:chemistry / Q000502:physiology*
chemical_list: D051153:Wnt Proteins
references.citation: Neuroscientist. 2002 Oct;8(5):497-511
references.pmid: 12374432
references.citation: Development. 2005 Jul;132(13):3079-92
references.pmid: 15930100
references.citation: J Cell Biol. 2004 Jan 19;164(2):243-53
references.pmid: 14734535
references.citation: J Neurosci. 2008 Oct 22;28(43):10875-84
references.pmid: 18945895
references.citation: Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2483-8
references.pmid: 17284594
references.citation: Growth Factors. 2005 Jun;23(2):111-6
references.pmid: 16019432
references.citation: Nat Cell Biol. 2001 Sep;3(9):802-8
references.pmid: 11533659
references.citation: Dev Neurobiol. 2008 Feb 1;68(2):152-65
references.pmid: 17963254
references.citation: Dev Cell. 2008 Nov;15(5):635-6
references.pmid: 19000826
references.citation: Neuron. 2008 Mar 13;57(5):705-18
references.pmid: 18341991
references.citation: Annu Rev Neurosci. 2008;31:339-58
references.pmid: 18558859
references.citation: Brain Res Brain Res Rev. 2000 Aug;33(1):1-12
references.pmid: 10967351
references.citation: Neuron. 2001 May;30(2):399-410
references.pmid: 11395002
references.citation: Nat Neurosci. 2008 Mar;11(3):262-8
references.pmid: 18278041
references.citation: Cell. 1996 May 17;85(4):501-12
references.pmid: 8653786
references.citation: Cell. 1996 May 17;85(4):513-23
references.pmid: 8653787
references.citation: Genetics. 2008 Dec;180(4):2057-71
references.pmid: 18832361
references.citation: Nat Cell Biol. 2005 May;7(5):463-73
references.pmid: 15892196
references.citation: Neuron. 2008 Oct 23;60(2):285-97
references.pmid: 18957220
references.citation: J Neurosci. 2004 Jul 28;24(30):6776-84
references.pmid: 15282282
references.citation: Mol Cell Neurosci. 2006 Oct;33(2):188-99
references.pmid: 16949836
references.citation: Nat Rev Neurosci. 2001 Nov;2(11):791-805
references.pmid: 11715056
references.citation: Cell. 2007 Aug 24;130(4):704-16
references.pmid: 17719547
references.citation: J Biol Chem. 2008 Aug 1;283(31):21668-75
references.pmid: 18541538
references.citation: J Cell Biol. 2000 Jul 10;150(1):205-12
references.pmid: 10893268
references.citation: Nat Neurosci. 2005 Jul;8(7):906-15
references.pmid: 15965473
references.citation: Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18812-7
references.pmid: 19020093
references.citation: Nat Neurosci. 2002 Feb;5(2):141-6
references.pmid: 11753421
references.citation: Curr Opin Cell Biol. 2005 Feb;17(1):47-54
references.pmid: 15661518
references.citation: J Biol Chem. 2003 Oct 3;278(40):38522-7
references.pmid: 12885777
references.citation: Nature. 1994 Dec 1;372(6505):461-4
references.pmid: 7984239
references.citation: Proc Natl Acad Sci U S A. 2006 May 16;103(20):7841-6
references.pmid: 16682643
references.citation: Dev Biol. 1997 Dec 1;192(1):31-44
references.pmid: 9405095
references.citation: Bioinform Biol Insights. 2008 Nov 03;2:369-81
references.pmid: 19812789
references.citation: Nature. 1993 Jan 28;361(6410):350-3
references.pmid: 8426654
references.citation: Annu Rev Neurosci. 1999;22:389-442
references.pmid: 10202544
references.citation: Neuron. 2009 Mar 12;61(5):721-33
references.pmid: 19285469
references.citation: Neuron. 2001 Jul 19;31(1):15-22
references.pmid: 11498047
references.citation: Nature. 2001 Apr 26;410(6832):1057-64
references.pmid: 11323662
references.citation: Neuron. 2002 Nov 14;36(4):635-48
references.pmid: 12441053
references.citation: Science. 2005 Nov 25;310(5752):1344-7
references.pmid: 16311339
references.citation: J Neurochem. 2006 Jun;97(6):1520-33
references.pmid: 16805766
references.citation: Trends Neurosci. 2007 Jun;30(6):268-75
references.pmid: 17467065
references.citation: Nat Neurosci. 2003 Oct;6(10):1017-8
references.pmid: 14502292
references.citation: J Mol Histol. 2008 Jun;39(3):329-37
references.pmid: 18392598
references.citation: Dev Cell. 2008 Nov;15(5):773-80
references.pmid: 19000841
references.citation: Nat Neurosci. 2008 Jan;11(1):19-27
references.pmid: 18084289
references.citation: Rev Endocr Metab Disord. 2006 Jun;7(1-2):41-9
references.pmid: 16944325
references.citation: Cell. 2006 Nov 3;127(3):591-606
references.pmid: 17081980
references.citation: Development. 2006 Dec;133(24):4993-5000
references.pmid: 17119023
references.citation: Commun Integr Biol. 2008;1(2):158-60
references.pmid: 19704879
references.citation: Neuron. 2002 Sep 12;35(6):1043-56
references.pmid: 12354395
references.citation: Cell. 2002 Nov 1;111(3):319-30
references.pmid: 12419243
references.citation: J Neurosci. 2007 Apr 11;27(15):3968-73
references.pmid: 17428970
references.citation: Neuron. 2005 May 19;46(4):581-94
references.pmid: 15944127
references.citation: Neuron. 2006 Jan 5;49(1):11-6
references.pmid: 16387635
references.citation: Mol Membr Biol. 2002 Jan-Mar;19(1):27-38
references.pmid: 11989820
references.citation: J Cell Sci. 1998 May;111 ( Pt 10):1351-61
references.pmid: 9570753
references.citation: Neuron. 2008 Nov 26;60(4):526-8
references.pmid: 19038209
references.citation: J Neurosci. 2003 May 1;23(9):3577-87
references.pmid: 12736328
references.citation: Curr Opin Neurobiol. 2006 Feb;16(1):74-82
references.pmid: 16386415
references.citation: Int Rev Neurobiol. 2006;75:267-85
references.pmid: 17137932
references.citation: J Neurosci. 2007 Jan 3;27(1):111-23
references.pmid: 17202478
references.citation: Cancer Cell. 2002 Oct;2(4):323-34
references.pmid: 12398896
references.citation: Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9924-9
references.pmid: 11493710
references.citation: J Biol Chem. 2003 Feb 21;278(8):6450-5
references.pmid: 12473646
references.citation: Cell. 2008 Oct 17;135(2):334-42
references.pmid: 18848351
references.citation: Mol Cell Neurosci. 2008 Jun;38(2):138-52
references.pmid: 18407517
references.citation: Hum Mol Genet. 2003 Apr 1;12(7):739-48
references.pmid: 12651869
references.citation: Neurochem Int. 2002 Nov;41(5):341-4
references.pmid: 12176076
references.citation: Dev Cell. 2009 Mar;16(3):325-7
references.pmid: 19289078
references.citation: Biosci Rep. 2005 Oct-Dec;25(5-6):309-27
references.pmid: 16307379
references.citation: Bioessays. 1994 Jun;16(6):395-404
references.pmid: 8080429
references.citation: Neuron. 2002 Aug 1;35(3):489-505
references.pmid: 12165471
references.citation: Nature. 2004 Sep 30;431(7008):578-82
references.pmid: 15457263
references.citation: Mol Cell Neurosci. 2006 Feb;31(2):251-62
references.pmid: 16243537
references.citation: Nat Neurosci. 2005 Jan;8(1):34-42
references.pmid: 15608632
references.citation: BMC Neurosci. 2005 Jun 28;6:44
references.pmid: 15985179