title: Optic nerve head morphologic characteristics in chronic angle-closure glaucoma and normal-tension glaucoma.
abstract: OBJECTIVE
  To determine whether the morphometric features of the optic disk in eyes with chronic angle-closure glaucoma (CACG) are different from those with normal-tension glaucoma (NTG).
  
  
  METHODS
  This is a retrospective, case-matched study. Patients with CACG or NTG in an early or moderate stage were recruited. On the basis of age, sex, and visual field mean defect, patients with CACG were matched to those with NTG on a case-by-case basis. Heidelberg retina tomography was used to evaluate the optic disk, and parameters were compared between the 2 groups.
  
  
  RESULTS
  Sixty-three patients were recruited for the study. Twenty cases (eyes) with CACG were matched to 20 cases (eyes) with NTG. The total, temporal/inferior, nasal/superior, and nasal/inferior rim area of the optic disk were significantly larger (P<0.05) in the CACG group. In patients with CACG rather than NTG, the cup volume in total and in each sector (except temporal) was significantly smaller (P=0.007 to 0.041). In patients with CACG rather than NTG, the mean cup depth and cup shape measure of the optic disk in total and in each sector (except temporal and temporal/inferior) were smaller (P=0.002 to 0.054).
  
  
  CONCLUSIONS
  The morphometric features of the optic disk in eyes with CACG are different from those with NTG.
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Peking University Eye Center, Beijing, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhao
authors.forename: Lingling
authors.initials: L
authors.lastname: Wu
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis* / Q000601:surgery; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D032801:Iridectomy; D053685:Laser Therapy; D008297:Male; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012189:Retrospective Studies; D014130:Trabeculectomy; D014794:Visual Fields
chemical_list: D000959:Antihypertensive Agents