title: Osseous metaplasia and mature bone formation with extramedullary hematopoiesis in follicular adenoma of thyroid gland.
abstract: Follicular adenomas of the thyroid may be subjected to degenerative changes like hemorrhagic and cystic changes, fibrosis, and calcification. Mature bone formation is a rare phenomenon, but extramedullary hematopoiesis (EMH) has also been rarely reported in thyroid gland. The combination of mature bone formation and EMH is rarer and has been reported, in a single case report, in a multinodular goitre. We describe a case of follicular adenoma with histologically proven osseous metaplasia and mature bone formation with EMH in a middle- aged woman, which, to our knowledge, is the first case in English language literature.
authors.affiliation: Department of Pathology, Government Medical College & Hospital, Chandigarh, India.
authors.forename: Mohan
authors.initials: M
authors.lastname: Harsh
authors.forename: Parul
authors.initials: P
authors.lastname: Dimri
authors.forename: Nitin M
authors.initials: NM
authors.lastname: Nagarkar
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008875:Middle Aged; D009999:Ossification, Heterotopic; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology*