[A case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response].
We report a case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response. The patient was a 72-year-old female with multiple liver metastases of cecal cancer. She underwent a right hemicolectomy and right salpingo-oophorectomy in a non-curative resection. Final findings revealed cecal cancer, type 3, 60 x 55 mm, pSI (right ovary), pN3, sH3, sP0, cM0, fStage IV, respectively. After surgery, chemotherapy with mFOLFOX6 was performed. After 4 courses, a significant tumor reduction (PR) was obtained. She died 1 year 2 months after surgery. This case suggests that chemotherapy with mFOLFOX6 is a potential regimen for AFP producing colon cancer.
Seshimo
Ken
K
Dept. of Surgery, Tottori Municipal Hospital.
Yamashita
Yutaka
Y
Oishi
Masahiro
M
Yokomichi
Naosuke
N
Ikeda
Hideaki
H
Katoh
Hiroshi
H
Yamamura
Masao
M
Kodera
Masahito
M
Maejima
Reijiro
R
Kobayashi
Keita
K
Takita
Keiko
K
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002430:Cecal Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000509:alpha-Fetoproteins; D002955:Leucovorin; D005472:Fluorouracil