Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring.
Wilson
Ian D
ID
Department of Clinical Pharmacology, Drug Metabolism, and Pharmacokinetics, AstraZeneca, Mereside, Macclesfield, Cheshire SK10 4TG, United Kingdom. ian.wilson@astrazeneca.com
D000082:Acetaminophen / Q000031:analogs & derivatives / Q000378:metabolism* / Q000493:pharmacokinetics / Q000652:urine; D000284:Administration, Oral; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics; D001419:Bacteria / Q000254:growth & development / Q000378:metabolism*; D003408:Cresols / Q000378:metabolism* / Q000652:urine; D041981:Gastrointestinal Tract / Q000378:metabolism* / Q000382:microbiology*; D054884:Host-Pathogen Interactions; D006801:Humans; D013431:Sulfates / Q000378:metabolism; D013463:Sulfuric Acid Esters / Q000378:metabolism / Q000652:urine
D018712:Analgesics, Non-Narcotic; D003408:Cresols; D013431:Sulfates; D013463:Sulfuric Acid Esters; C032538:4-cresol; D000082:Acetaminophen; C408690:4-cresol sulfate; C037386:acetaminophen glucuronide
Food Chem Toxicol. 2003 May;41(5):631-6
12659715
Acta Paediatr Scand. 1991 Jun-Jul;80(6-7):602-10
1867075
FEBS Lett. 2002 Oct 23;530(1-3):191-6
12387891
Am J Pharmacogenomics. 2003;3(6):361-70
14672516
Nature. 2006 Dec 21;444(7122):1022-3
17183309
Nature. 2006 Apr 20;440(7087):1073-7
16625200
Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12511-6
16895997
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14728-33
19667173
Gut. 1989 Jul;30(7):971-7
2759492
N Engl J Med. 1981 Oct 1;305(14):789-94
7266632
Cell. 2008 Sep 5;134(5):714-7
18775301
Biochem Pharmacol. 1993 Sep 1;46(5):953-7
8373447
Mol Syst Biol. 2007;3:124
17625512
Gastroenterology. 1988 Jul;95(1):117-23
3371607
Cancer Epidemiol Biomarkers Prev. 2000 Aug;9(8):781-6
10952094
Curr Pharm Des. 2009;15(13):1519-23
19442168
Nat Rev Drug Discov. 2008 Feb;7(2):123-9
18239669
J Hyg (Lond). 1986 Feb;96(1):59-65
3950398