Activity of telomerase in ovarian cancer cells. Clinical implications.
Estimation of telomerase activity in cell nuclei of ovarian malignant tumours may provide an independent prognostic index. The test for telomerase activity in tumour cell nuclei may be accepted as a useful diagnostic test with application for differential diagnoses of benign ovarian tumours vs tumours of a borderline or malignant character.
Lubin
J
J
Department of Gynaecological Oncology, Poznan University of Medical Sciences, Poznan, Poland. jolaostap@wp.pl
Markowska
J
J
Markowska
A
A
Stanisławiak
J
J
Lukaszewski
T
T
D000230:Adenocarcinoma / Q000201:enzymology*; D000328:Adult; D000368:Aged; D018394:CA-125 Antigen / Q000032:analysis; D016022:Case-Control Studies; D002467:Cell Nucleus / Q000201:enzymology*; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008875:Middle Aged; D009367:Neoplasm Staging; D010048:Ovarian Cysts / Q000201:enzymology; D010051:Ovarian Neoplasms / Q000201:enzymology*; D011237:Predictive Value of Tests; D016019:Survival Analysis; D019098:Telomerase / Q000378:metabolism*; D044767:Ubiquitin-Protein Ligases / Q000032:analysis
D018394:CA-125 Antigen; C111164:BRAP protein, human; D044767:Ubiquitin-Protein Ligases; D019098:Telomerase