Women with hypertensive pregnancies have difficulties in regaining pre-pregnancy weight and show metabolic disturbances.
The aim was to determine maternal weight gain and body composition during pregnancy and 3 months postpartum in women with uncomplicated singleton and twin pregnancies and in women with gestational diabetes (GDM) and gestational hypertension (GH). This prospective study includes four groups of subjects: those with an uncomplicated pregnancy (n = 32), those with a diagnosis of GH (n = 28), those with a diagnosis of GDM (n = 52), and those with twin pregnancy (n = 11). Their body compositions were estimated by a bioimpedance analysis and fasting lipids and glucose levels were determined during the pregnancy and 3 months after pregnancy. Women with GDM were 11.7 kg heavier than the reference group before pregnancy, whereas weight before pregnancy was not different in other investigated groups. Weight loss after delivery was attenuated in GH group. Percentage body fat remained elevated in women with GDM (34.1 +/- 7.0%) and hypertension (31.5 +/- 6.4%) at 3 months after pregnancy. Also their total cholesterol and low-density lipoprotein (LDL)-cholesterol levels as well as fasting glucose remained elevated in comparison to values of the reference group. In conclusion, women with hypertensive pregnancies, though not overweight before pregnancy, gain and retain excess gestational weight and this leads to metabolic abnormalities similar to those seen in women GDM. Thus, postpartum period appears to be critical for weight management and interventional programs are called for.
Suntio
Katariina
K
Department of Obstetrics and Gynecology, Kuopio University Hospital and University of Kuopio, Kuopio, Finland.
Saarelainen
Heli
H
Laitinen
Tomi
T
Valtonen
Pirjo
P
Heiskanen
Nonna
N
Lyyra-Laitinen
Tiina
T
Vanninen
Esko
E
Heinonen
Seppo
S
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition; D016640:Diabetes, Gestational / Q000097:blood / Q000503:physiopathology*; D005260:Female; D005387:Finland; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000503:physiopathology*; D008055:Lipids / Q000097:blood; D049590:Postpartum Period / Q000097:blood; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000097:blood; D011446:Prospective Studies; D013997:Time Factors; D014427:Twins; D015430:Weight Gain; D015431:Weight Loss
D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids