title: Case of inflammatory fibroid polyp of the esophagogastric junction.
abstract: Upper gastrointestinal endoscopy of a 25-year-old man with heartburn revealed an elevated lesion in the esophagogastric junction (EGJ). Piecemeal endoscopic mucosal resection (EMR) followed by histopathological examination led to a diagnosis of inflammatory fibroid polyp (IFP). After EMR, the heartburn persisted despite giving a proton pump inhibitor (PPI), and the residual lesion gradually enlarged and a transverse mucosal break developed on the esophageal side of it. However, the combined administration of the PPI and an H2 receptor antagonist reduced the heartburn, and led to endoscopic regression of the lesion and disappearance of the transverse mucosal break. IFP of the esophagogastric junction is extremely rare, and this case is interesting in that potent inhibition of gastric acid secretion resulted in the regression of the lesion.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan. yamane@jikei.ac.jp
authors.forename: Tateki
authors.initials: T
authors.lastname: Yamane
authors.forename: Kan
authors.initials: K
authors.lastname: Uchiyama
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ishii
authors.forename: Hironori
authors.initials: H
authors.lastname: Ishii
authors.forename: Reo
authors.initials: R
authors.lastname: Takizawa
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Omura
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Fujise
authors.forename: Hisao
authors.initials: H
authors.lastname: Tajiri
mesh_terms: D000328:Adult; D004935:Esophageal Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D004943:Esophagogastric Junction; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011127:Polyps / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D054328:Proton Pump Inhibitors / Q000528:radiation effects / Q000627:therapeutic use; D013272:Stomach Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors