title: Quantifying the PR interval pattern during dynamic exercise and recovery.
abstract: We present a novel analysis tool for time delay estimation in electrocardiographic signal processing. This tool enhances PR interval estimation (index of the atrioventricular conduction time) by limiting the distortion effect of the T wave overlapping the P wave at high heart rates. Our approach consists of modeling the T wave, cancelling its influence, and finally estimating the PR intervals during exercise and recovery with the proposed generalized Woody method. Different models of the T wave are presented and compared in a statistical summary that quantitatively justifies the improvements introduced by this study. Among the different models tested, we found that a piecewise linear function significantly reduces the T wave-induced bias in the estimation process. Combining this modeling with the proposed time delay estimation method leads to accurate PR interval estimation. Using this method on real ECGs recorded during exercise and its recovery, we found: 1) that the slopes of PR interval series in the early recovery phase are dependent on the subjects' training status (average of the slopes for sedentary men = 0.11 ms/s, and for athlete men = 0.28 ms/s), and 2) an hysteresis phenomenon exists in the relation PR/RR intervals when data from exercise and recovery are compared.
authors.affiliation: Laboratory I3S, Centre National de la Recherche Scientifique, University of Nice, Sophia Antipolis, France. cabasson@i3s.unice.fr
authors.forename: Aline
authors.initials: A
authors.lastname: Cabasson
authors.forename: Olivier
authors.initials: O
authors.lastname: Meste
authors.forename: Grégory
authors.initials: G
authors.lastname: Blain
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bermon
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D003198:Computer Simulation; D004562:Electrocardiography / Q000379:methods*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D016018:Least-Squares Analysis; D008297:Male; D015233:Models, Statistical; D016011:Normal Distribution; D012815:Signal Processing, Computer-Assisted