TTMPP: An efficient organocatalyst in the ring-opening of aziridines with silylated nucleophiles.
The ring-opening of N-tosylaziridines with silylated nucleophiles catalyzed by tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP) afforded the corresponding beta-functionalized sulfonamides in excellent yield under mild reaction conditions.
Matsukawa
Satoru
S
Department of Science Education, Faculty of Education, Ibaraki University, Ibaraki, 310-8512, Japan. smatsuka@mx.ibaraki.ac.jp
Tsukamoto
Kumiko
K
D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry; D017646:Organosilicon Compounds / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D014297:Trimethylsilyl Compounds / Q000737:chemistry
D001388:Aziridines; D003486:Cyanides; D017646:Organosilicon Compounds; D010720:Phosphines; D014297:Trimethylsilyl Compounds; C544519:tris(2,4,6-trimethoxyphenyl)phosphine; C033132:aziridine; C058010:trimethylsilyl cyanide