Changing pattern of esophageal cancer incidence in New Mexico: a 30-year evaluation.
OBJECTIVE
The incidence of esophageal adenocarcinoma has increased over the last 30 years, especially in non-Hispanic whites (nHw). Recent work indicates an increase in Hispanic Americans (HA). It is important to understand the effect of ethnicity on cancer occurrence over a prolonged interval.


METHODS
We searched the New Mexico Tumor Registry for all cases of esophageal cancer from 1 January 1973 to 31 December 2002. Inclusion criteria were histologic diagnosis of adenocarcinoma or squamous cell carcinoma, ethnicity and gender. Incidence rates for both were compared among ethnic groups in 5-year intervals.


RESULTS
Nine hundred eighty-eight patients met the criteria. Esophageal adenocarcinoma incidence rates/100,000 population increased significantly over 30 years; 1973-1977, 0.4 cases; 1978-1982, 0.4 cases; 1983-1987, 0.6 cases; 1988-1992, 1.2 cases, 1993-1997, 1.6 cases and 1998-2002, 2.2 cases; P < 0.001. Squamous cell carcinoma incidence rates remained unchanged during the interval. In nHw and HA, adenocarcinoma incidence rates increased significantly during the study period. In all minority groups, squamous cell carcinoma remained the major type.


CONCLUSIONS
Esophageal adenocarcinoma incidence among nHw and HA increased from 1973 to 2002 in New Mexico. Squamous cell carcinoma remains predominant in minorities. Ethnicity may influence the histology or indicate an increased risk for certain types of esophageal cancer.
Vega
Kenneth J
KJ
Division of Gastroenterology, University of Florida Health Science Center/Jacksonville, Suite 300, Jacksonville, FL 32207, USA. kenneth.vega@jax.ufl.edu
Jamal
M Mazen
MM
Wiggins
Charles L
CL
D000230:Adenocarcinoma / Q000208:ethnology*; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000208:ethnology*; D004938:Esophageal Neoplasms / Q000208:ethnology*; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007198:Indians, North American / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009516:New Mexico / Q000453:epidemiology; D012042:Registries; D012189:Retrospective Studies; D013997:Time Factors; D044465:White People / Q000706:statistics & numerical data
J Assoc Acad Minor Phys. 1999;10(2):44-7
10826008
Am J Gastroenterol. 2004 Apr;99(4):582-8
15089886
J Natl Med Assoc. 2005 Nov;97(11):1471-8
16334494
Cancer. 1988 Feb 1;61(3):612-7
3338027
Endoscopy. 1995 Jan;27(1):19-26
7601030
Clin Gastroenterol Hepatol. 2008 Jan;6(1):30-4
18063419
Br J Cancer. 1990 Sep;62(3):440-3
2206952
N Engl J Med. 1985 Oct 3;313(14):857-9
4033716
CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96
18287387
Arch Intern Med. 1991 Nov;151(11):2212-6
1953225
Cancer Causes Control. 2007 Aug;18(6):585-93
17406989
Gastroenterology. 1987 Jan;92(1):118-24
3781178
Gastroenterology. 1993 Feb;104(2):510-3
8425693
Am J Gastroenterol. 2000 Sep;95(9):2352-6
11007241
Br J Cancer. 1995 Feb;71(2):411-5
7841063
J Clin Gastroenterol. 1998 Jan;26(1):11-3
9492855
Ann Clin Lab Sci. 1996 Nov-Dec;26(6):480-6
8908317
Am J Gastroenterol. 1989 Dec;84(12):1494-6
2596449
Dig Dis Sci. 1998 May;43(5):1038-41
9590419
JAMA. 1991 Mar 13;265(10):1287-9
1995976
J Clin Gastroenterol. 1995 Oct;21(3):254-5
8648065