Effects of infrared radiation and heat on human skin aging in vivo.
Sunlight damages human skin, resulting in a wrinkled appearance. Since natural sunlight is polychromatic, its ultimate effects on the human skin are the result of not only the action of each wavelength separately, but also interactions among the many wavelengths, including UV, visible light, and infrared (IR). In direct sunlight, the temperature of human skin rises to about 40 degrees C following the conversion of absorbed IR into heat. So far, our knowledge of the effects of IR radiation or heat on skin aging is limited. Recent work demonstrates that IR and heat exposure each induces cutaneous angiogenesis and inflammatory cellular infiltration, disrupts the dermal extracellular matrix by inducing matrix metalloproteinases, and alters dermal structural proteins, thereby adding to premature skin aging. This review provides a summary of current research on the effects of IR radiation and heat on aging in human skin in vivo.Journal of Investigative Dermatology Symposium Proceedings (2009) 14, 15-19; doi:10.1038/jidsymp.2009.7.
Cho
Soyun
S
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
Shin
Mi Hee
MH
Kim
Yeon Kyung
YK
Seo
Jo-Eun
JE
Lee
Young Mee
YM
Park
Chi-Hyun
CH
Chung
Jin Ho
JH
D003094:Collagen / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D004249:DNA Damage; D000071837:Fibrillins; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D007259:Infrared Rays / Q000009:adverse effects; D015603:Keratinocytes / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D020782:Matrix Metalloproteinases / Q000378:metabolism; D008840:Microfilament Proteins / Q000378:metabolism; D009389:Neovascularization, Pathologic / Q000209:etiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D012867:Skin / Q000098:blood supply / Q000293:injuries / Q000378:metabolism / Q000528:radiation effects; D015595:Skin Aging / Q000502:physiology / Q000528:radiation effects*; D050916:TRPV Cation Channels / Q000378:metabolism; D014333:Tropoelastin / Q000378:metabolism; D053802:Tryptases / Q000378:metabolism
D016207:Cytokines; D000071837:Fibrillins; D008840:Microfilament Proteins; D017382:Reactive Oxygen Species; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; D014333:Tropoelastin; D003094:Collagen; D053802:Tryptases; D020782:Matrix Metalloproteinases