The relationship between preoperative alignment stability and postoperative motor outcomes in children with esotropia.
OBJECTIVE
To examine the effect of preoperative alignment stability on postoperative motor outcomes in children who underwent surgery for esotropia.


METHODS
One hundred sixty-seven subjects (68 with infantile esotropia and 99 with acquired esotropia) aged less than 6 years had surgery after completing 18 weeks of follow-up as part of an observational study. Preoperative alignment was classified as stable, uncertain, or unstable, based on measurements taken at baseline and every 6 weeks for 18 weeks. Distance alignment measured by prism and alternate cover test was compared among stability classification groups at 6 weeks and 6 months after surgery.


RESULTS
Among subjects with infantile esotropia, median 6-week postoperative deviation was 2(Delta), 6(Delta), and 2(Delta) for subjects with stable, uncertain, and unstable preoperative alignment, respectively (p = 0.73 for stable vs unstable). Median 6-month postoperative deviation was 1(Delta), 9(Delta), and 1(Delta) for stable, uncertain, and unstable, respectively (p = 1.00 for stable vs unstable). Among subjects with acquired esotropia, median 6-week postoperative deviation was 6(Delta), 4(Delta), and 4(Delta) for subjects with stable, uncertain, and unstable preoperative alignment, respectively (p = 0.69 for stable vs unstable). Median 6-month postoperative deviation was 8(Delta), 4(Delta), and 6(Delta) for stable, uncertain, and unstable, respectively (p = 0.22 for stable vs unstable).


CONCLUSIONS
Postoperative alignment at 6 weeks and 6 months appears similar in children with stable versus unstable preoperative esotropia. Nevertheless, our finding should be interpreted with caution due to small sample size.
Jaeb Center for Health Research, Tampa, Florida 33647, USA. pedig@jaeb.org
Christiansen
Stephen P
SP
Chandler
Danielle L
DL
Holmes
Jonathan M
JM
Bacal
Darron A
DA
Birch
Eileen
E
Donahue
Sean P
SP
Mohney
Brian G
BG
Repka
Michael X
MX
Verderber
Lisa C
LC
D002648:Child; D002675:Child, Preschool; D004948:Esotropia / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009801:Oculomotor Muscles / Q000503:physiopathology*; D013508:Ophthalmologic Surgical Procedures; D011184:Postoperative Period; D015348:Vision, Binocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology
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