title: Effects of limonoids from Cipadessa fruticosa on fall armyworm.
abstract: Six mexicanolide limonoids isolated from the dichloromethane extract of the fruits of Cipadessa fruticosa Blume (Meliaceae) were evaluated against Spodoptera frugiperda (J. E. Smith). Gedunin was used as a positive control. When incorporated into an artificial diet of neonates at 50.0 mg kg(-1), febrifugin A showed 73.3% mortality. All the compounds showed moderate insecticidal activity, except for ruageanin A, when compared with the control. Febrifugin also showed growth inhibition and antifeedant activities (at 100.0 mg kg(-1)). The correlation between the insecticidal activity of the isolated compounds and their chemical structure was discussed.
authors.affiliation: Departamento de Química, Universidade Federal de São Carlos, Caixa Postal 676, CEP 13565-905, São Carlos--SP, Brazil.
authors.forename: Andreia P
authors.initials: AP
authors.lastname: Matos
authors.forename: Ana C
authors.initials: AC
authors.lastname: Leite
authors.forename: Luciane G
authors.initials: LG
authors.lastname: Batista-Pereira
authors.forename: Paulo C
authors.initials: PC
authors.lastname: Vieira
authors.forename: Josäo B
authors.initials: JB
authors.lastname: Fernandes
authors.forename: Maria Fátima das G F
authors.initials: MF
authors.lastname: da Silva
mesh_terms: D000818:Animals; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D029582:Meliaceae / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D010880:Piperidines / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D011679:Pupa / Q000187:drug effects; D011799:Quinazolines / Q000494:pharmacology; D018411:Spodoptera / Q000187:drug effects*
chemical_list: D007306:Insecticides; D036701:Limonins; D010880:Piperidines; D010936:Plant Extracts; D011799:Quinazolines; C106014:gedunin; C001207:febrifugine