Hyperpolarized gas MR Imaging of the lung: current status as a research tool.
Hyperpolarized gas magnetic resonance imaging has been explored extensively as a promising tool for the quantitative evaluation of regional pulmonary pathophysiology. This noninvasive technique is capable of providing both structural information down to the level of the alveolar microstructure and functional information, such as dynamic ventilation, intrapulmonary partial pressure of oxygen, and alveolar surface area. This study reviews the role of hyperpolarized 3-helium and 129-xenon magnetic resonance imaging in this research.
Matsuoka
Shin
S
Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Patz
Samuel
S
Albert
Mitchell S
MS
Sun
Yanping
Y
Rizi
Rahim R
RR
Gefter
Warren B
WB
Hatabu
Hiroto
H
D006371:Helium; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014978:Xenon
D006371:Helium; D014978:Xenon