title: Mind-body complementary alternative medicine use and quality of life in adolescents with inflammatory bowel disease.
abstract: BACKGROUND
  Mind-body complementary and alternative medicine (CAM) modalities (e.g., relaxation or meditation) for symptom management have not been well studied in adolescents with inflammatory bowel disease (IBD). The purposes of this study were to: 1) determine the prevalence of 5 types of mind-body CAM use, and consideration of use for symptom management; 2) assess characteristics associated with regular mind-body CAM use; and 3) examine whether regular and/or considered mind-body CAM use are associated with health-related quality of life (HRQOL).
  
  
  METHODS
  Sixty-seven adolescents with IBD ages 12-19 recruited from a children's hospital completed a questionnaire on CAM use and the Pediatric Quality of Life Inventory. Logistic regression models were estimated for regular and considered CAM use.
  
  
  RESULTS
  Participants mean (SD) age was 15.5 (2.1) years; 37 (55%) were female; 53 (79%) were white; and 20 (30%) had moderate disease severity. Adolescents used prayer (62%), relaxation (40%), and imagery (21%) once/day to once/week for symptom management. In multivariate analyses, females were more likely to use relaxation (odds ratio [OR] = 4.38, 95% confidence interval [CI] = 1.25-15.29, c statistic = 0.73). Younger adolescents were more likely to regularly use (OR = 0.63, 95% CI = 0.42-0.95, c statistic = 0.72) or consider using (OR = 0.77, 95% CI = 0.59-1.00, c statistic = 0.64) meditation. Adolescents with more severe disease (OR = 4.17, 95% CI = 1.07-16.29, c statistic = 0.83) were more willing to consider using relaxation in the future. Adolescents with worse HRQOL were more willing to consider using prayer and meditation for future symptom management (P < 0.05).
  
  
  CONCLUSIONS
  Many adolescents with IBD either currently use or would consider using mind-body CAM for symptom management.
authors.affiliation: Department of Family Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0840, USA. sian.cotton@uc.edu
authors.forename: Sian
authors.initials: S
authors.lastname: Cotton
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Humenay Roberts
authors.forename: Joel
authors.initials: J
authors.lastname: Tsevat
authors.forename: Maria T
authors.initials: MT
authors.lastname: Britto
authors.forename: Paul
authors.initials: P
authors.lastname: Succop
authors.forename: Meghan E
authors.initials: ME
authors.lastname: McGrady
authors.forename: Michael S
authors.initials: MS
authors.lastname: Yi
mesh_terms: D000293:Adolescent; D000529:Complementary Therapies / Q000706:statistics & numerical data*; D005260:Female; D006304:Health Status; D006801:Humans; D019018:Imagery, Psychotherapy; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D016015:Logistic Models; D008297:Male; D019122:Meditation; D026441:Mind-Body Therapies / Q000706:statistics & numerical data*; D015999:Multivariate Analysis; D000297:Psychology, Adolescent; D011788:Quality of Life; D012064:Relaxation Therapy / Q000706:statistics & numerical data; D012919:Social Behavior; D011795:Surveys and Questionnaires; D015013:Yoga
references.citation: J Pediatr Psychol. 2004 Jun;29(4):243-57
references.pmid: 15148347
references.citation: J Pediatr Gastroenterol Nutr. 2001 Feb;32(2):171-7
references.pmid: 11321388
references.citation: Am J Gastroenterol. 2002 Feb;97(2):382-8
references.pmid: 11866277
references.citation: J Adolesc Health. 2009 May;44(5):485-92
references.pmid: 19380097
references.citation: Ambul Pediatr. 2001 Mar-Apr;1(2):122-5
references.pmid: 11888385
references.citation: Patient Educ Couns. 2008 Sep;72(3):436-42
references.pmid: 18657376
references.citation: Pain Res Manag. 2006 Winter;11(4):217-23
references.pmid: 17149454
references.citation: Inflamm Bowel Dis. 2004 Sep;10(5):599-605
references.pmid: 15472521
references.citation: Inflamm Bowel Dis. 2005 Apr;11(4):400-6
references.pmid: 15803032
references.citation: Med Care. 2001 Aug;39(8):800-12
references.pmid: 11468499
references.citation: J Pediatr Gastroenterol Nutr. 2009 Jan;48(1):55-60
references.pmid: 19172124
references.citation: Clin Gastroenterol Hepatol. 2003 Nov;1(6):446-52
references.pmid: 15017644
references.citation: J Paediatr Child Health. 2004 Dec;40(12):681-4
references.pmid: 15569284
references.citation: Semin Gastrointest Dis. 1999 Jan;10(1):14-9
references.pmid: 10065768
references.citation: Am J Gastroenterol. 1998 May;93(5):697-701
references.pmid: 9625111
references.citation: Dig Dis Sci. 1979 Aug;24(8):620-4
references.pmid: 467213
references.citation: Qual Life Res. 2004 Jun;13(5):1011-9
references.pmid: 15233514
references.citation: Evid Based Complement Alternat Med. 2008 Mar;5(1):41-50
references.pmid: 18317547
references.citation: Scand J Gastroenterol. 2001 Apr;36(4):375-82
references.pmid: 11336162
references.citation: Arch Pediatr Adolesc Med. 2002 Oct;156(10):1042-4
references.pmid: 12361452
references.citation: Pediatrics. 1995 Jul;96(1 Pt 1):105-10
references.pmid: 7596696
references.citation: Gastroenterol Clin Biol. 2006 Jan;30(1):14-23
references.pmid: 16514377
references.citation: Nat Clin Pract Gastroenterol Hepatol. 2008 Nov;5(11):624-36
references.pmid: 18825145
references.citation: Cochrane Database Syst Rev. 2007 Oct 17;(4):CD005110
references.pmid: 17943840
references.citation: J Pediatr. 2009 Apr;154(4):527-34
references.pmid: 19028387