Allopatric femtosecond laser gas-bubble formation in a closed system.
OBJECTIVE
To test a possible mechanism for allopatric gas-bubble formation in femtosecond laser-assisted surgery using an experimental closed system.


METHODS
Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USA.


METHODS
Plastic bottles were filled with balanced salt solution (BSS). Femtosecond laser (IntraLase) flap-mode cuts were made on the walls of the BSS bottles. After femtosecond laser application, the BSS bottles were viewed under the excimer laser microscope and the results photographed. Next, the BSS bottles and laser cuts were imaged with optical coherence tomography.


RESULTS
In-bottle gas bubbles were consistently produced in the closed system. No cut lines crossed the inner wall of the BSS bottles.


CONCLUSIONS
Results show that in situ gas-bubble formation as a mechanism for gas-bubble formation is a possible alternative to gas traveling through the anterior segment and into the intraflap laser space.
Ide
Takeshi
T
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Yoo
Sonia H
SH
Lee
Richard K
RK
O'Brien
Terrence P
TP
D005740:Gases; D053685:Laser Therapy; D054018:Lasers, Excimer; D045423:Microbubbles; D008954:Models, Biological; D010969:Plastics; D013524:Surgical Flaps; D041623:Tomography, Optical Coherence
D005740:Gases; D010969:Plastics