title: F-18 FDG PET/CT findings in a patient with bilateral orbital and gastric mucosa-associated lymphoid tissue lymphomas.
abstract: Orbital mucosa-associated lymphoid tissue (MALT) lymphoma is an uncommon disease, while the incidence is recently increasing. We describe the F-18 fluorodeoxyglucose positron emission tomography computerized tomography (FDG PET/CT) findings in a case of bilateral orbital MALT lymphomas with a coexisting gastric lesion. Although only the lesion in the left orbit was initially identified on MR imaging, FDG PET/CT scan unexpectedly and additionally could identify the tiny lesion of the contralateral orbit and the gastric lesion. This patient received radiotherapy to all these lesions, with a combination of rituximab monoclonal antibody therapy. The follow-up PET/CT studies at 3, 6, and 9 months and 1.5 years after treatment showed regression or disappearance of all these FDG-avid lesions. Accurate localization and staging are crucial to select an adequate treatment in MALT lymphoma at any location. This case indicates the feasibility of FDG PET/CT scan for accurate localization and staging and also for monitoring treatment in patients with orbital MALT lymphoma.
authors.affiliation: Department of Radiology, St. Hill Hospital, Yamaguchi, Japan. sugar@sthillhp.or.jp
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Suga
authors.forename: Kawakami
authors.initials: K
authors.lastname: Yasuhiko
authors.forename: Atsuto
authors.initials: A
authors.lastname: Hiyama
authors.forename: Koumei
authors.initials: K
authors.lastname: Takeda
authors.forename: Naofumi
authors.initials: N
authors.lastname: Matsunaga
mesh_terms: D019788:Fluorodeoxyglucose F18; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009918:Orbital Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D049268:Positron-Emission Tomography; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18