Prevalence and distribution of Peste des petits ruminants virus antibodies in various districts of Tanzania.
Despite the widespread prevalence of infection with Peste des petits ruminants virus (PPRV) in goats and sheep industry in Asia and sub-Saharan Africa, there have been few, if any, structured population-based studies examining the epidemiology of this infection in Tanzania. In this study, we investigated the seroprevalence, and risk factors, of Peste des petitis ruminants(PPR) in sheep and goat flocks from seven different geographical administration authorities (Ngorongoro, Monduli, Longido, Karatu, Mbulu, Siha and Simanjiro) located in Northern Tanzania. Serum samples from 657 and 892 sheep and goats, respectively, corresponding to 91 sheep/goat flocks and 43 villages were collected. Competitive enzyme linked immunosorbent assay (c-ELISA) was used to detect the presence of antibodies in the serum against PPRV. Chi-square analysis and multivariable logistic regression model were used to identify risk factors for PPRV seropositivity. Findings suggested that the sero-positive cases were significantly higher in goats than in sheep (49.5% versus 39.8%; P=0.002). The overall seroprevalence of PPRV infection in small ruminants was 45.8%. Highest seroprevalence (42.6-88.02%) was observed in Mbulu, Siha, Longido, Ngorongoro districts, while antibodies less than 40% to none were found in serum from Monduli, Karatu and Simanjiro, respectively. These findings confirm natural transmission of PPRV under field condition for the first time in Tanzania. Results may be correlated with variations in the sheep and goat husbandry practices within different geographic localities, the uncontrolled movement of animals, the levels of natural immunity and the sharing of grazing field amongst agro and pastoralists.
Swai
Emmanuel Senyael
ES
Veterinary Investigation Centre (VIC), Box 1068, Arusha, Tanzania. esswai@gmail.com
Kapaga
A
A
Kivaria
F
F
Tinuga
D
D
Joshua
G
G
Sanka
P
P
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000453:epidemiology / Q000276:immunology / Q000821:virology; D006041:Goats / Q000276:immunology / Q000821:virology; D008297:Male; D029021:Peste-des-Petits-Ruminants / Q000453:epidemiology* / Q000276:immunology; D018107:Peste-des-petits-ruminants virus / Q000276:immunology*; D015995:Prevalence; D012756:Sheep / Q000276:immunology / Q000821:virology; D012757:Sheep Diseases / Q000453:epidemiology / Q000276:immunology / Q000821:virology; D013636:Tanzania / Q000453:epidemiology
D000914:Antibodies, Viral
Rev Sci Tech. 1990 Dec;9(4):935-81
2132714
Vet Microbiol. 2004 Jan 14;98(1):3-15
14738776
BMC Vet Res. 2008 Sep 12;4:34
18786275
J Vet Med B Infect Dis Vet Public Health. 2004 Mar;51(2):68-71
15030603
Trop Anim Health Prod. 1994 May;26(2):69-73
7941031
Trop Anim Health Prod. 1985 Aug;17(3):135-40
4060235
Vet Microbiol. 2002 Aug 25;88(2):153-9
12135634
Vet Rec. 1995 Feb 25;136(8):199-200
7754596
Vet Microbiol. 1990 May;22(4):341-52
2114052
Trop Anim Health Prod. 2000 Dec;32(6):391-403
11147279
Trop Anim Health Prod. 2008 Jun;40(5):363-8
18509945
Trop Anim Health Prod. 1984 May;16(2):115-8
6485096
Clin Diagn Lab Immunol. 2005 Apr;12(4):542-7
15817764
Trop Anim Health Prod. 2008 Oct;40(7):521-7
18716909
Vet Rec. 2000 Apr 15;146(16):473-4
10819135
Vet Microbiol. 1995 May;44(2-4):307-17
8588326
Trop Anim Health Prod. 2008 Oct;40(7):517-9
18716908