title: The role of EUTox in uremic toxin research.
abstract: In this publication, we review the activities of the European Uremic Toxin Work Group (EUTox) in the field of uremic toxin research. Founded in 1999 under the umbrella of the European Society of Artificial Organs (ESAO), and active since 2000, this group focuses essentially on questions related to solute retention and removal during chronic kidney disease, and on the deleterious impact of those solutes on biological/biochemical systems. As of January 1, 2009, the group had met 28 times; it organized the third meeting, "Uremic Toxins in Cardiovascular Disease," which took place in October 2008 in Amiens, France. The current group is composed of 25 members belonging to 23 European research institutions. As of November 1, 2008, in total 69 papers had been published to which at least two different research groups belonging to EUTox have contributed in a collaborative effort. Of these, 40 papers were on original research and eight were specific EUTox reviews or position statements. A website (http://www.eutox.info) summarizes all relevant information concerning the work group. EUTox also developed an interactive uremic toxin database, where concentrations of known toxins are displayed, to be used by researchers in the field. In the future, EUTox intends to continue its focus on bench to bedside research with specific consideration of proteomics, metabonomics, secretomics, and genomics.
authors.affiliation: Department of Internal Medicine, Nephrology Section, University Hospital, Gent, Belgium. raymond.vanholder@ugent.be
authors.forename: Raymond
authors.initials: R
authors.lastname: Vanholder
authors.forename: Omar
authors.initials: O
authors.lastname: Abou-Deif
authors.forename: Angel
authors.initials: A
authors.lastname: Argiles
authors.forename: Ulrich
authors.initials: U
authors.lastname: Baurmeister
authors.forename: Joachim
authors.initials: J
authors.lastname: Beige
authors.forename: Peter
authors.initials: P
authors.lastname: Brouckaert
authors.forename: Philippe
authors.initials: P
authors.lastname: Brunet
authors.forename: Gerald
authors.initials: G
authors.lastname: Cohen
authors.forename: Peter Paul
authors.initials: PP
authors.lastname: De Deyn
authors.forename: Tilman B
authors.initials: TB
authors.lastname: Drüeke
authors.forename: Danilo
authors.initials: D
authors.lastname: Fliser
authors.forename: Griet
authors.initials: G
authors.lastname: Glorieux
authors.forename: Stefan
authors.initials: S
authors.lastname: Herget-Rosenthal
authors.forename: Walter H
authors.initials: WH
authors.lastname: Hörl
authors.forename: Joachim
authors.initials: J
authors.lastname: Jankowski
authors.forename: Achim
authors.initials: A
authors.lastname: Jörres
authors.forename: Ziad A
authors.initials: ZA
authors.lastname: Massy
authors.forename: Harald
authors.initials: H
authors.lastname: Mischak
authors.forename: Alessandra F
authors.initials: AF
authors.lastname: Perna
authors.forename: Juan Mariano
authors.initials: JM
authors.lastname: Rodriguez-Portillo
authors.forename: Goce
authors.initials: G
authors.lastname: Spasovski
authors.forename: Bernd G
authors.initials: BG
authors.lastname: Stegmayr
authors.forename: Peter
authors.initials: P
authors.lastname: Stenvinkel
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Thornalley
authors.forename: Christoph
authors.initials: C
authors.lastname: Wanner
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wiecek
mesh_terms: D026683:Advisory Committees / Q000458:organization & administration*; D035843:Biomedical Research; D016208:Databases, Factual; D005060:Europe; D006801:Humans; D033181:Information Dissemination; D014118:Toxins, Biological / Q000502:physiology*; D014511:Uremia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy
chemical_list: D014118:Toxins, Biological