Ovarian hyperstimulation, hyperprolactinaemia and LH gonadotroph adenoma.
This report considers a highly exceptional case of ovarian hyperstimulation syndrome due to a gonadotroph adenoma secreting LH in a 31-year-old patient who presented with amenorrhoea and galactorrhoea syndrome and a complex bilateral ovarian mass. Magnetic resonance imaging revealed a pituitary adenoma, and laboratory tests corroborated the hyperprolactinaemia without other hormonal pituitary abnormalities. Ovarian hyperstimulation syndrome due to a gonadotroph adenoma with normal gonadotrophins is extremely rare. Most of the described cases are caused by FSH adenomas. Due to the originality of the case, it was considered useful for understanding the management of this entity, and it is proposed that LH adenomas should also be considered in the differential diagnosis of patients with spontaneous ovarian hyperstimulation syndrome.
Castelo-Branco
Camil
C
Hospital Clínic, Faculty of Medicine, University of Barcelona, Spain. castelobranco@ub.edu
del Pino
Marta
M
Valladares
Esther
E
D000236:Adenoma / Q000150:complications* / Q000378:metabolism; D000328:Adult; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications*; D007986:Luteinizing Hormone / Q000378:metabolism*; D016471:Ovarian Hyperstimulation Syndrome / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications* / Q000378:metabolism
D007986:Luteinizing Hormone