title: [Expression of aquaporin-1 in human oligohydramnios placenta and fetal membranes].
abstract: OBJECTIVE
  To detect aquaporin-1 mRNA (AQP1) expression in human oligohydramnios placenta and fetal membranes.
  
  
  METHODS
  Placenta and fetal membranes samples were obtained from 5 women with oligohydramnios and 5 with normal amniotic fluid volume. AQP-1 mRNA expression in the tissue samples was detected by semi-quantitative RT-PCR.
  
  
  RESULTS
  The expression of AQP1 mRNA was significantly lower in oligohydramnios placenta than in normal pregnancy placenta at term (P<0.05), and also significantly lower in oligohydramnios fetal membranes than in normal fetal membranes at term (P<0.05).
  
  
  CONCLUSIONS
  Alterations in AQP1 mRNA expressions in human placenta and fetal membranes may play an important role in the disorder of maternal-fetal fluid exchange and amniotic fluid volume.
authors.affiliation: Department of Obstetrics and Gynecology, Third Affiliated Hospital of Guangzhou Medical College, Guangzhou, China. haorongzeng@163.com
authors.forename: Rong-Zeng
authors.initials: RZ
authors.lastname: Hao
authors.forename: Hui-Shu
authors.initials: HS
authors.lastname: Liu
authors.forename: Zheng-Fang
authors.initials: ZF
authors.lastname: Xiong
mesh_terms: D000328:Adult; D051398:Aquaporin 1 / Q000235:genetics / Q000378:metabolism*; D005321:Extraembryonic Membranes / Q000378:metabolism*; D005260:Female; D006801:Humans; D016104:Oligohydramnios / Q000378:metabolism*; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D055815:Young Adult
chemical_list: C496020:AQP1 protein, human; D012333:RNA, Messenger; D051398:Aquaporin 1