A novel iodine-mediated tandem cyclization-cycloaddition reaction leading to polyoxacyclic ring systems.
A novel iodine-catalyzed tandem cyclization-cycloaddition reaction of ortho-alkynyl-substituted benzaldehydes leading to polyoxacyclic ring systems has been developed, which represents a useful approach towards the synthesis of the oxabicyclo-[3.2.1]octane ring skeleton found in a variety of natural products.
Xie
Yong-Xin
YX
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.
Yan
Ze-Yi
ZY
Qian
Bo
B
Deng
Wen-Ye
WY
Wang
Dan-Zhu
DZ
Wu
Lu-Yong
LY
Liu
Xue-Yuan
XY
Liang
Yong-Min
YM
D000480:Alkynes / Q000737:chemistry; D001547:Benzaldehydes / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D006577:Heterocyclic Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D008956:Models, Chemical; D008968:Molecular Conformation; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000480:Alkynes; D001547:Benzaldehydes; D006577:Heterocyclic Oxides; D011083:Polycyclic Compounds; D007455:Iodine