title: Towards enzyme-like enantioselectivity in the gas phase: conformational control of selectivity in chiral macrocyclic dimers.
abstract: Conformational factors in self-assembled chiral tetraamide macrocycles control their gas-phase enantioselectivity towards the ethyl ester of naphthylalanine to levels typical of enzymes.
authors.affiliation: Dipartimento di Chimica e Tecnologie del Farmaco, Università di Roma La Sapienza, Rome, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Fraschetti
authors.forename: Marco
authors.initials: M
authors.lastname: Pierini
authors.forename: Claudio
authors.initials: C
authors.lastname: Villani
authors.forename: Francesco
authors.initials: F
authors.lastname: Gasparrini
authors.forename: Stefano Levi
authors.initials: SL
authors.lastname: Mortera
authors.forename: Maurizio
authors.initials: M
authors.lastname: Speranza
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives / Q000737:chemistry; D002384:Catalysis; D005740:Gases / Q000737:chemistry*; D006860:Hydrogen Bonding; D007700:Kinetics; D047028:Macrocyclic Compounds / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D005740:Gases; D047028:Macrocyclic Compounds; D000409:Alanine