title: The efficacy and safety of 10,600-nm carbon dioxide fractional laser for acne scars in Asian patients.
abstract: BACKGROUND
  The nonablative 1,550-nm erbium-doped fractional photothermolysis system (FPS) has been effectively used for scar treatments, but it seems that several sessions of treatment must be delivered to achieve satisfactory improvement.
  
  
  OBJECTIVE
  To evaluate the efficacy and safety of the combined use of two treatment modes of an ablative 10,600-nm carbon dioxide fractional laser system (CO(2) FS) on acne scars.
  
  
  METHODS
  Twenty Korean patients with atrophic acne scars treated with a single session of Ultrapulse Encore laser (Lumenis Inc., Santa Clara, CA) were enrolled. The laser fluences were delivered to the scars using the Deep FX mode. Additional treatment using the Active FX mode was performed throughout the entire face.
  
  
  RESULTS
  Follow-up results revealed that one patient had clinical improvement of 76% to 100%, nine had improvements of 51% to 75%, seven had moderate improvements of 26% to 50%, and three had minimal to no improvements. The mean duration of post-therapy crusting or scaling was 6.3+/-3.0 days, and post-therapy erythema lasted 2.8+/-4.6 days.
  
  
  CONCLUSIONS
  We suggest that CO(2) FS used with a combination of two different treatment modes may provide a new treatment algorithm for acne scars in Asians.
authors.affiliation: Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Sung Bin
authors.initials: SB
authors.lastname: Cho
authors.forename: Sang Ju
authors.initials: SJ
authors.lastname: Lee
authors.forename: Jin Moon
authors.initials: JM
authors.lastname: Kang
authors.forename: Young Koo
authors.initials: YK
authors.lastname: Kim
authors.forename: Won Soon
authors.initials: WS
authors.lastname: Chung
authors.forename: Sang Ho
authors.initials: SH
authors.lastname: Oh
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000328:Adult; D044466:Asian People; D002921:Cicatrix / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D054020:Lasers, Gas; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult