title: [Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum].
abstract: BACKGROUND
  We present the case of small-cell lung carcinoma metastatic to the iris, the course of the disease and management options.
  
  
  METHODS
  A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma. Systemic chemotherapy was indicated after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was controlled as well. Good visual functions were preserved during the treatment.
  
  
  CONCLUSIONS
  Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small-cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient's quality of life.
authors.affiliation: Klinika nemocí ocních a optometrie FN u sv. Anny a LF MU v Brne. jurecka@neovize.cz
authors.forename: T
authors.initials: T
authors.lastname: Jurecka
authors.forename: S
authors.initials: S
authors.lastname: Skorkovská
authors.forename: H
authors.initials: H
authors.lastname: Coupková
authors.forename: V
authors.initials: V
authors.lastname: Postránecká
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D015811:Iris Neoplasms / Q000556:secondary*; D008175:Lung Neoplasms / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D055752:Small Cell Lung Carcinoma / Q000175:diagnosis / Q000556:secondary*