Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62).
Deng
Hai
H
Centre for Biomolecular Sciences, School of Chemistry, University of St. Andrews, St. Andrews, KY16 9ST, UK.
McMahon
Stephen A
SA
Eustáquio
Alessandra S
AS
Moore
Bradley S
BS
Naismith
James H
JH
O'Hagan
David
D
D020134:Catalytic Domain; D004789:Enzyme Activation / Q000187:drug effects; D008716:Methionine Adenosyltransferase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008848:Micromonosporaceae / Q000201:enzymology; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D043902:Pyrococcus horikoshii / Q000201:enzymology; D012436:S-Adenosylmethionine / Q000378:metabolism*; D014867:Water / Q000494:pharmacology*
D014867:Water; D012436:S-Adenosylmethionine; D008716:Methionine Adenosyltransferase