Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava.
Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). The SEF of the liver was successfully resected, and the infiltrated IVC was also removed together with the liver tumor. Histopathological examination of the tumor showed typical histopathology of SEF. Immunohistochemically, the tumor was positive for vimentin. Recurrence was noted 7 mo after surgery. After chemotherapy, the recurrent tumor was resected surgically, and histopathological examination showed similar findings to those of the primary tumor. To our knowledge, this is the first report of SEF of the liver with tumor invasion of the IVC.
Tomimaru
Yoshito
Y
Department of Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka E-2, Suita, 565-0871, Osaka, Japan.
Nagano
Hiroaki
H
Marubashi
Shigeru
S
Kobayashi
Shogo
S
Eguchi
Hidetoshi
H
Takeda
Yutaka
Y
Tanemura
Masahiro
M
Kitagawa
Toru
T
Umeshita
Koji
K
Hashimoto
Nobuyuki
N
Yoshikawa
Hideki
H
Wakasa
Kenichi
K
Doki
Yuichiro
Y
Mori
Masaki
M
D000328:Adult; D015622:Epithelioid Cells / Q000473:pathology*; D005354:Fibrosarcoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D012598:Sclerosis; D014682:Vena Cava, Inferior / Q000473:pathology*