[Functional MR Imaging: new tool to predict outcome for cervical carcinoma of uterus treated by concomitant radiochemotherapy?].
The treatment of advanced cervix is concomitant radiochemotherapy. Local prognosis and global survival depend on tumoral volume, locoregional extension and radio sensitivity of the lesion. This one is function of tumoral hypoxia, tumoral interstitial pressure and existence of an anaemia. DCE-MRI allows to quantify pilot vascular parameters of the first two factors. Combined analysis: tumoral volume, anaemia and vascular parameters before and in the course of treatment allows a strong correlation with the risk of local recurrence and global survival.
Taïeb
S
S
Département d'Imagerie, Centre Oscar-Lambret, 59000 Lille, France. s-taieb@o-lambret.fr
Faivre-Pierret
M
M
Nickers
P
P
Lesoin
A
A
Narducci
F
F
Ceugnart
L
L
D000328:Adult; D000740:Anemia / Q000150:complications / Q000453:epidemiology; D003131:Combined Modality Therapy; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D009389:Neovascularization, Pathologic / Q000453:epidemiology; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D013113:Spin Labels; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*
D013113:Spin Labels