Coexistence of prostate cancer, gynecomastia, renal failure, melanonychia, and wrist lump.
Although prostate cancer is among the most frequent malignancies in the elderly, this tumor may be under-reported, and it seems that its socioeconomic burden is not well-estimated. Chronic urinary obstruction caused by the cancer may cause renal failure, with hemorrhagic tendency, neurologic disturbances, cutaneous disorders, and diverse fingernail changes. Black or brown nail pigmentation has been associated with benign and malignant conditions, including antineoplastic drugs' side effects, subungual metastases, and melanoma. Metastasis of fingernail melanoma can affect lymph nodes from the wrist to elbow and axillary regions. Coexistent melanonychia and wrist lump, mimicking melanoma with sentinel lymph node is reported. It is recommended to consider the differential diagnosis of nail changes due to chronic renal failure.
dos Santos
Vitorino Modesto
VM
Catholic University Medical Course, Brasília-DF, Brazil. vitorinomodesto@gmail.com
de Vasconcelos
Rodrigo Abdalla
RA
de Paula
Fernando Henrique
FH
Alves Tubino
Paulo Victor
PV
Turra
Thiago Zavascki
TZ
Gagliardi Castilho
Ivan
I
D000368:Aged; D003937:Diagnosis, Differential; D006177:Gynecomastia / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008297:Male; D009260:Nail Diseases / Q000175:diagnosis / Q000209:etiology*; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000150:complications*; D014953:Wrist / Q000473:pathology*