Headache in kidney transplantation.
The aim of this retrospective study was to determine the relevance of the symptom "headache" in kidney transplanted patients, since few studies have considered headache as a clinically significant complication in this condition. A total of 83 consecutive kidney transplant patients underwent to neurological examination and a detailed headache history was taken. The headache history considered the period before kidney disease, during renal failure, during dialysis treatment and after transplantation. Diagnosis was made according to International Headache Criteria (ICDH-II) (2004). Our results reveal an occurrence of headache after kidney transplantation in 44.5% of the patients, which is higher than rates reported for the general population and in the only specific comparable study on liver transplant patients. These data suggest the need for prospective studies to explore the causal mechanisms by which headache develops with frequency in kidney transplant patients, and in particular to determine the role of immunosuppressive therapy.
Maggioni
Ferdinando
F
Headache Centre, Department of Neurosciences, University of Padua, Via Giustiniani, 5, 35128 Padua, Italy. ferdinando.maggioni@unipd.it
Mantovan
Maria Cristina
MC
Rigotti
Paolo
P
Cadrobbi
Roberto
R
Mainardi
Federico
F
Mampreso
Edoardo
E
Ermani
Mario
M
Cortelazzo
Silvia
S
Zanchin
Giorgio
G
D000293:Adolescent; D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects; D015984:Causality; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects; D003956:Dialysis / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D020773:Headache Disorders / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D051437:Renal Insufficiency / Q000150:complications; D012189:Retrospective Studies; D055815:Young Adult
D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone