title: Nickel-catalyzed cycloaddition of salicylic acid ketals to alkynes via elimination of ketones.
abstract: An intermolecular nickel-catalyzed addition reaction has been developed where salicylic acid ketals react with alkynes to afford substituted chromones. A mechanistic rationale is proposed, implying beta-elimination of ketone from ring strained seven-membered nickelacycle to generate a five-membered oxa-nickelacycle intermediate.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ooguri
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Nakai
authors.forename: Takuya
authors.initials: T
authors.lastname: Kurahashi
authors.forename: Seijiro
authors.initials: S
authors.lastname: Matsubara
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction; D020156:Salicylic Acid / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007659:Ketones; D009532:Nickel; D020156:Salicylic Acid