A locally acquired falciparum malaria via nosocomial transmission in Korea.
A 57-year old man who was admitted to an emergency room of a tertiary hospital with hemoptysis developed malarial fever 19 days later and then died from severe falciparum malaria 2 days later. He had not traveled outside of Korea for over 30 years. Through intensive interviews and epidemiological surveys, we found that a foreign patient with a recent history of travel to Africa was transferred to the same hospital with severe falciparum malaria. We confirmed through molecular genotyping of the MSP-1 gene that Plasmodium falciparum genotypes of the 2 patients were identical. It is suggested that a breach of standard infection control precautions resulted in this P. falciparum transmission between 2 patients in a hospital environment. This is the first report of a nosocomial transmission of falciparum malaria in Korea.
Kim
Jung-Yeon
JY
Division of Malaria and Parasitic Disease, Korea Centers for Disease Control and Prevention (KCDC), Seoul, Korea.
Kim
Jeong-Su
JS
Park
Mi-Hyun
MH
Kang
Young-A
YA
Kwon
Jun-Wook
JW
Cho
Shin-Hyeong
SH
Lee
Byeong-Chul
BC
Kim
Tong-Soo
TS
Lee
Jong-Koo
JK
D000349:Africa; D000595:Amino Acid Sequence; D000818:Animals; D003428:Cross Infection / Q000469:parasitology / Q000635:transmission*; D017809:Fatal Outcome; D006801:Humans; D007723:Korea; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission*; D008297:Male; D020066:Merozoite Surface Protein 1 / Q000737:chemistry / Q000235:genetics; D008875:Middle Aged; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification*; D015800:Protozoan Proteins / Q000737:chemistry / Q000235:genetics; D016415:Sequence Alignment; D014195:Travel
D020066:Merozoite Surface Protein 1; D015800:Protozoan Proteins