title: Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles.
abstract: A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.
authors.affiliation: Department of Molecular Therapeutics and Translational Research Institute, The Scripps Research Institute, Scripps Florida, 130 Scripps Way No. A2A, Jupiter, Florida 33458, USA.
authors.forename: Romain
authors.initials: R
authors.lastname: Noël
authors.forename: Xinyi
authors.initials: X
authors.lastname: Song
authors.forename: Rong
authors.initials: R
authors.lastname: Jiang
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Chalmers
authors.forename: Patrick R
authors.initials: PR
authors.lastname: Griffin
authors.forename: Theodore M
authors.initials: TM
authors.lastname: Kamenecka
mesh_terms: D000640:Amitrole / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000640:Amitrole