title: Laparoscopy or laparotomy? A comparison of 240 patients with early-stage endometrial cancer.
abstract: BACKGROUND
  This study aimed to compare the safety and efficacy of laparoscopy and laparotomy in the surgical treatment of early endometrial cancer, especially in obese women.
  
  
  METHODS
  The results obtained after laparoscopic surgical treatment of early endometrial cancer (International Federation of Gynecology and Obstetrics (FIGO) stage 1 or 2) in patients between 1996 and 2007 were compared with an age- and tumour-matched historical group of patients treated with laparotomy between 1988 and 1996. All the patients underwent hysterectomy, bilateral salpingo-oophorectomy, and pelvic + or - paraaortic lymphadenectomy.
  
  
  RESULTS
  Both groups included 120 patients with a preoperative diagnosis of early endometrial cancer. The postoperative diagnosis was endometrial cancer stage 1 or 2 for 89% of the cases in both groups. The mean operating time was 170 min for the laparotomy group compared with 178 min for the laparoscopy group (nonsignificant difference). The estimated intraoperative blood loss was significantly greater in the laparotomy group, and the hospital stay was significantly shorter in the laparoscopy group.
  
  
  CONCLUSIONS
  The results show that early endometrial cancer can be treated effectively by laparoscopy. Because of this study's retrospective design, the results should be interpreted with caution. However, the advantages of this method for obese patients are evident. The age and weight of these patients should not be used as a contraindication for laparoscopy.
authors.affiliation: Department of Obstetrics and Gynecology, Inselspital, Bern University Hospital and University of Bern, Effingerstrasse 102, CH 3012, Bern, Switzerland.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Santi
authors.forename: Annette
authors.initials: A
authors.lastname: Kuhn
authors.forename: Thomas
authors.initials: T
authors.lastname: Gyr
authors.forename: Markus
authors.initials: M
authors.lastname: Eberhard
authors.forename: Silke
authors.initials: S
authors.lastname: Johann
authors.forename: Andreas R
authors.initials: AR
authors.lastname: Günthert
authors.forename: Michael D
authors.initials: MD
authors.lastname: Mueller
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D010535:Laparoscopy / Q000379:methods*; D007813:Laparotomy / Q000379:methods*; D008197:Lymph Node Excision; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D010052:Ovariectomy; D012189:Retrospective Studies; D016896:Treatment Outcome