title: Cardiovascular nursing on human genomics: what do cardiovascular nurses need to know about congestive heart failure?
abstract: This paper presents the main causes of heart failure (HF) and an update on the genetics studies on each cause. The review includes a delineation of the etiology and fundamental pathophysiology of HF and provides rational for treatment for the patient and family. Various cardiomyopathies are discussed, including primary cardiomyopathies, mixed cardiomyopathies, cardiomyopathies that involve altered cardiac muscle along with generalized multiorgan disorders, and various cardiovascular conditions, such as coronary artery disease (ischemic cardiomyopathy) and hypertension (hypertensive cardiomyopathy). A brief review of pharmacogenetics and HF is presented. The application of the genetic components of cardiomyopathy and pharmacogenetics is included to enhance cardiovascular nursing care.
authors.affiliation: The University of Texas Health Science Center School of Nursing at Houston, 6901 Bertner, Houston, TX 77030, USA. lorraine.frazier@uth.tmc.edu
authors.forename: Lorraine
authors.initials: L
authors.lastname: Frazier
authors.forename: Shu-Fen
authors.initials: SF
authors.lastname: Wung
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Sparks
authors.forename: Cathy
authors.initials: C
authors.lastname: Eastwood
mesh_terms: D009202:Cardiomyopathies / Q000235:genetics / Q000451:nursing / Q000503:physiopathology; D005820:Genetic Testing; D015894:Genome, Human; D006333:Heart Failure / Q000235:genetics / Q000451:nursing* / Q000503:physiopathology; D006801:Humans; D024802:Nurse's Role; D010597:Pharmacogenetics; D012307:Risk Factors