title: Macroradical initiated polymerisation of acrylic and methacrylic monomers.
abstract: An approach has been developed for the grafting of monomers onto poly(trimethylolpropane trimethacrylate) (polyTRIM) particles using 2,2-diethyl dithiocarbamic acid benzyl ester (DDCABE) as an initiator. A set of polymers was prepared with this technique over different lengths of time and the kinetics of the reaction studied experimentally. It was found that the grafting of initiator to the polymeric support followed a second order reaction, while the subsequent addition of monomers from solution into the polyTRIM macroradicals followed a first order reaction. The living nature of the iniferter modified macroradicals permits easy consecutive grafting of multiple polymeric layers, allowing straightforward functionalisation of particles. However, the effectiveness of the grafted initiator decreased with each cycle of polymerisation. This technique can be used for a wide range of applications in analytical and biochemistry.
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, Bedfordshire, UK.
authors.forename: Irene
authors.initials: I
authors.lastname: Mijangos
authors.forename: António
authors.initials: A
authors.lastname: Guerreiro
authors.forename: Elena
authors.initials: E
authors.lastname: Piletska
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Whitcombe
authors.forename: Kal
authors.initials: K
authors.lastname: Karim
authors.forename: Iva
authors.initials: I
authors.lastname: Chianella
authors.forename: Sergey
authors.initials: S
authors.lastname: Piletsky
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D002219:Carbamates / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D005609:Free Radicals / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry*; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D016062:Porosity; D014466:Ultraviolet Rays
chemical_list: D000179:Acrylates; D002219:Carbamates; D004952:Esters; D005609:Free Radicals; D008689:Methacrylates; D011108:Polymers; C004919:ethylene dimethacrylate; C036658:acrylic acid; C070766:carbamic acid; C028643:trimethylolpropane trimethacrylate