Is it recurrent cryptococcal meningitis or immune reconstitution inflammatory syndrome?
We report a case of a 45-year-old patient with a history of cryptococcal meningitis who was started on antiretroviral therapy. The patient presented four months later with complaints of fever and memory loss. Lumbar puncture revealed positive cryptococcal antigen and therefore the patient was treated for recurrent cryptococcal meningitis. Unfortunately, the patient did not improve even after two weeks. The diagnosis of immune reconstitution was made at this time and steroids were started. The patient showed remarkable improvement.
Lodha
A
A
Maimonides Medical Center, Brooklyn, NY 11219, USA. ankurlodha@gmail.com
Haran
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D023241:Antiretroviral Therapy, Highly Active; D003937:Diagnosis, Differential; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000175:diagnosis*; D008297:Male; D016919:Meningitis, Cryptococcal / Q000175:diagnosis*; D008875:Middle Aged; D012008:Recurrence