[Bone regenerate structural organization in experimentally reproduced defects of mandible branches under xenogenic stromal cells influence].
In experiment on rabbits by histomorphometric method it was shown that after the use during 4 months of titanium plate with the culture of marrow mesenchymal stromal cells there happened full infill of mandible defect by lamellar bone tissue. In control group (titanium plate with inactivated culture of cells) the defect was replaced by regenerate, the most part of it was rough fibrous connective tissue. In experimental group in the central parts of the defect regenerate were characterized by bigger weight of lamellar bone matrix if compared with the peripheral parts of the defect that testified to higher level of its differentiation. Use of stem cells on titanium carrier led in 4 months experiment to full infill of jaw defect by lamellar bone tissue.
Mal'ginov
N N
NN
Grigor'ian
A S
AS
Frolova
E N
EN
Lebedenko
I Iu
IIu
Matveeva
V N
VN
Volozhin
A I
AI
D000818:Animals; D001857:Bone Matrix; D001861:Bone Regeneration; D002478:Cells, Cultured; D003627:Data Interpretation, Statistical; D008334:Mandible / Q000166:cytology / Q000601:surgery*; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D011817:Rabbits; D013997:Time Factors; D014025:Titanium
D014025:Titanium