title: Leg ulceration in chronic venous insufficiency caused by an absent inferior vena cava.
abstract: We report here the case of a 55-year-old Japanese man with a one-year history of multiple ulcers on the left crural region. He had had pronounced varicose veins on both legs and the abdominal region for 35 years. Computed tomography images of the thoracic and abdominal regions showed the absence of an inferior vena cava, with pronounced dilatation of paravertebral venous plexus, cutaneous and azygous veins. Conservative topical treatments led to complete healing of the ulcers in one month. An absent inferior vena cava is an uncommon abnormality, often complicated by cardiac and other visceral malformations. It is a rare cause of chronic leg ulcers.
authors.affiliation: Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan. hamano@showa.gunma-u.ac.jp
authors.forename: Hiroo
authors.initials: H
authors.lastname: Amano
authors.forename: Yayoi
authors.initials: Y
authors.lastname: Nagai
authors.forename: Yukie
authors.initials: Y
authors.lastname: Endo
authors.forename: Tomoko
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishikawa
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage; D001401:Azygos Vein / Q000000981:diagnostic imaging / Q000473:pathology; D002908:Chronic Disease; D004108:Dilatation, Pathologic; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography / Q000379:methods; D012837:Silver Sulfadiazine / Q000008:administration & dosage; D053828:Stockings, Compression; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D054079:Vascular Malformations / Q000150:complications* / Q000000981:diagnostic imaging; D014682:Vena Cava, Inferior / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D012837:Silver Sulfadiazine