title: Polymyxin B and colistimethate are comparable as to efficacy and renal toxicity.
abstract: We compared 41 patients who received colistimethate with 41 who received polymyxin B for the treatment of serious infections caused by carbapenem-resistant Acinetobacter spp. and found both polymyxins have similar efficacy and toxicity.
authors.affiliation: Department of Infection Control of Hospital das Clínicas, Rua Dr. Ovídio Pires de Campos, São Paulo-SP 05403-010, Brazil.
authors.forename: Maura S
authors.initials: MS
authors.lastname: Oliveira
authors.forename: Gladys V B
authors.initials: GV
authors.lastname: Prado
authors.forename: Silvia F
authors.initials: SF
authors.lastname: Costa
authors.forename: Renato S
authors.initials: RS
authors.lastname: Grinbaum
authors.forename: Anna S
authors.initials: AS
authors.lastname: Levin
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D003091:Colistin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011112:Polymyxin B / Q000009:adverse effects* / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; C004691:colistinmethanesulfonic acid; D011112:Polymyxin B; D003091:Colistin