A role for the ribosome in development.
Development of a multicellular organism involves coordinated cell division, growth and specialization to generate different cell types that contribute to organized tissues, distinct organs and a higher order body plan. This coordinated process requires tight regulation of gene expression, which is mediated by multiple transcriptional, post-transcriptional, translational and post-translational control mechanisms. As I discuss here, recent studies on ribosomal protein genes and ribosome assembly genes indicate that the basic translational machinery of the cell, the ribosome, has a regulatory role in plant development. A comparison between plants and animals reveals both divergent trends in the genome content of ribosomal proteins and intriguing potential overlaps in the role of the ribosome in development.
Byrne
Mary E
ME
John Innes Centre, Norwich Research Park, Colney, Norwich NR47UH, UK. mary.byrne@bbsrc.ac.uk
D000818:Animals; D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D005057:Eukaryotic Cells / Q000378:metabolism; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D012269:Ribosomal Proteins / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism*
D012269:Ribosomal Proteins