title: QT duration and dispersion in patients with anomalous origins of coronary arteries.
abstract: BACKGROUND
  Coronary artery anomalies have been reported to show various symptoms ranging from chest pain and dyspnea to cardio-respiratory arrest and sudden death. In this study, we attempted to assess the changes in QT interval duration and dispersion in anomalous origins of coronary arteries (AOCA).
  
  
  METHODS
  Nineteen AOCA patients (mean age: 52 +/- 11 years) and 30 healthy control subjects (mean age: 50 +/- 12 years) were included in the study. Minimum and maximum corrected QT intervals, and corrected QT dispersion were calculated. The two groups were compared in terms of QT dispersion and QT duration.
  
  
  RESULTS
  There was no difference between the two groups in terms of baseline demographic characteristics. Maximum corrected QT intervals (QTc max), minimum corrected QT intervals (QTc min), and corrected QT dispersion were higher in AOCA patients than controls (452 +/- 38 vs 411 +/- 25 ms [P = 0.0001], 402 +/- 31 vs 383 +/- 28 ms [P = 0.048], and 51 +/- 30 vs 28 +/- 12 ms [P = 0.001], respectively).
  
  
  CONCLUSIONS
  In the patients with anomalous origins of coronary arteries, QT dispersion that is an indicator of sudden cardiac death and arrhythmias frequency increased. QTc max, QTc min, and corrected QT dispersion are higher in patients with anomalous origin of the coronary artery than in control subjects.
authors.affiliation: Kartal Kosuyolu Yüksek Ihtisas Research Hospital, Cardiology, Istanbul, Turkey. ramazankargin@yahoo.com
authors.forename: Ramazan
authors.initials: R
authors.lastname: Kargin
authors.forename: Selcuk
authors.initials: S
authors.lastname: Pala
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akçakoyun
authors.forename: Ozlem
authors.initials: O
authors.lastname: Esen
authors.forename: Aykut
authors.initials: A
authors.lastname: Demirkiran
authors.forename: Hekim
authors.initials: H
authors.lastname: Karapinar
authors.forename: Mubariz
authors.initials: M
authors.lastname: Rasulzada
authors.forename: Atila
authors.initials: A
authors.lastname: Bitigen
authors.forename: Yunus
authors.initials: Y
authors.lastname: Emiroglu
authors.forename: Nihal
authors.initials: N
authors.lastname: Ozdemir
mesh_terms: D001145:Arrhythmias, Cardiac / Q000150:complications* / Q000175:diagnosis*; D003330:Coronary Vessel Anomalies / Q000150:complications* / Q000175:diagnosis*; D003331:Coronary Vessels; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged