Panton Valentine leukocidin MSSA leading to multi-organ failure.
We report a case of a 15-year-old boy who developed multiple organ failure secondary to a sport injury leading to infection with a Panton Valentine Leukocidin (PVL) secreting Community-Acquired Methicillin Sensitive Staphylococcus Aureus (CA MSSA). Aggressive antibiotic therapy eventually led to recovery.
Low
T B
TB
Department of Respiratory Medicine, RCSI Education & Research Center, Smurfit Building, Beaumont Hospital, Dublin 9. teckboonlow1@rcsi.ie
Harty
L
L
Murray
M
M
Andrews
C
C
O'Neill
S J
SJ
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001265:Athletic Injuries / Q000150:complications*; D001427:Bacterial Toxins; D017714:Community-Acquired Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D005098:Exotoxins / Q000378:metabolism; D005436:Floxacillin / Q000627:therapeutic use; D006801:Humans; D007956:Leukocidins / Q000378:metabolism; D008297:Male; D016139:Martial Arts / Q000293:injuries; D016106:Methicillin Resistance / Q000187:drug effects; D009102:Multiple Organ Failure / Q000209:etiology*; D012293:Rifampin / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000378:metabolism; D014859:Warfarin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000904:Antibiotics, Antitubercular; D000925:Anticoagulants; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D005436:Floxacillin; D014859:Warfarin; D012293:Rifampin