NeuroCog FX: computerized screening of cognitive functions in patients with epilepsy.
NeuroCog FX, a computerized neuropsychological screening instrument for serial examinations of patients with epilepsy and other neurological diseases, was developed to fill the gap between unspecific ratings and comprehensive assessments. Eight subtests address attention, working memory, verbal and figural memory, and language. The test duration is less than 30min. In research contexts, the test can be applied at multiple sites by nonacademic personnel. Normative data were recorded from healthy subjects (N=244, age range=16-75years; retest: N=44; validation: N=40) and unselected patients from an epileptology unit (N=212; retest: N=94; validation: N=126). Psychometric analyses confirmed sufficient reliability and concurrent validity, particularly in patients. NeuroCog FX memory and overall performance scores showed "fair" to "good" diagnostic utility with respect to deficits revealed by established tests. NeuroCog FX provides reliable and valid measures of cognitive performance and may be used in clinical and research contexts as a screening instrument.
Hoppe
Christian
C
Department of Epileptology, University of Bonn Medical Centre, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. christian.hoppe@ukb.uni-bonn.de
Fliessbach
Klaus
K
Schlegel
Uwe
U
Elger
Christian E
CE
Helmstaedter
Christoph
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001288:Attention; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004827:Epilepsy / Q000150:complications*; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008570:Memory, Short-Term; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011594:Psychometrics; D012016:Reference Values; D015203:Reproducibility of Results; D014706:Verbal Learning; D055815:Young Adult