Allergen avoidance approaches in food allergy management.
Dietary elimination of causative food ingredients, usually food proteins, is the basis of treating food hypersensitivity. Proper diagnostic assessment is essential to avoid burdening children with unnecessary dietary restrictions with potential adverse effects. Diagnosis requires a detailed history, allergen elimination, and re-challenge with suspected foods. Complete elimination of causative food components depends on professional counseling and training of the patient and family, and transparent labeling of food products. Elimination diets carry the risk of inducing insufficient supplies of critical nutrients with adverse effects on health and wellbeing, particularly in children with exclusion of foods that provide a major part of dietary supply and patients with multiple food allergies. Infants and young children with cow's milk allergy, who have not been fully breastfed, require milk substitutes based on extensively hydrolyzed protein or amino acids. Elimination diets must be supervised and monitored to a similar degree as drug treatments, and the need for continued dietary elimination should be reviewed on a regular basis and re-challenges considered.
Koletzko
Sibylle
S
Division of Paediatric Gastroenterology and Hepatology, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany. sibylle.koletzko@med.uni-muenchen.de
Koletzko
Berthold
B
D000485:Allergens / Q000008:administration & dosage / Q000009:adverse effects* / Q000032:analysis; D017028:Caregivers / Q000193:education; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions; D005504:Food Analysis; D005506:Food Contamination; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000178:diet therapy*; D005515:Food Labeling; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000008:administration & dosage / Q000737:chemistry; D007231:Infant, Newborn; D044342:Malnutrition / Q000517:prevention & control; D016269:Milk Hypersensitivity / Q000178:diet therapy; D009752:Nutritional Status
D000485:Allergens