Difference between fasting and nonfasting triglyceridemia; the influence of waist circumference.
OBJECTIVE
Postprandial hypertriglyceridemia is recognized as an independent risk factor for cardiovascular disease. The aim of this study was to identify differences between fasting and postprandial TG levels, focusing on the influence of waist circumference.


METHODS
Subjects included 1,505 men and 798 women aged 3865 years who were not taking medications for diabetes or dyslipidemia. Fasting TG levels were measured after an overnight fast, and postprandial TG levels were measured 2 hours after a standardized rice-based lunch (total 740 kcal, 20 g fat, 30 g protein, and 110 g carbohydrates) in the afternoon on the same day.


RESULTS
Fasting and postprandial TG levels were highly correlated in both men (r=0.86, p<0.001) and women (r=0.84, p<0.001). Waist circumference was positively correlated with fasting TG (r=0.38 in men and r=0.36 in women) and postprandial TG (r=0.42 in men and r=0.45 in women), respectively. On multiple regression analyses, the association of waist circumference with postprandial TG was still significant (standardized beta=0.10 in men and standardized beta=0.15 in women, p<0.001) after the inclusion of HbA1c, age, high-density-lipoprotein (HDL)-cholesterol, alcohol consumption, and fasting TG in the regression model.


CONCLUSIONS
Postprandial TG has a better relation with waist circumference than fasting TG.
Oka
Rie
R
Department of Internal Medicine, Hokuriku Central Hospital, Japan. ririoka@goo.jp
Kobayashi
Junji
J
Miura
Katsuyuki
K
Nagasawa
Shinya
S
Moriuchi
Tadashi
T
Hifumi
Senshu
S
Miyamoto
Susumu
S
Kawashiri
Masa-Aki
MA
Nohara
Atsushi
A
Inazu
Akihiro
A
Takeda
Yoshiyu
Y
Mabuchi
Hiroshi
H
Yagi
Kunimasa
K
Yamagishi
Masakazu
M
D000328:Adult; D000368:Aged; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference
D014280:Triglycerides