title: Autopsy findings of a case with oxalosis.
abstract: Oxalosis, deposition of calcium oxalate in tissues, is the final stage of hyperoxaluric syndromes. Being a rare entity, it is often missed, or the diagnosis is delayed, since the definitive diagnosis requires special laboratory tests. Kidneys, the walls of blood vessels, and bones are the major sites for crystal deposition. We report the autopsy findings of a 4-year-old girl who presented with end-stage renal disease in which the clinical presentation was consistent with primary hyperoxaluria Type I. The case is unusual, as there was extensive crystal deposition throughout the body, including in tissues that are rarely involved, such as ovaries, fallopian tubes, uterus, thymus, salivary glands, pancreas, and bladder.
authors.affiliation: Ege University, Faculty of Medicine, Department of Pathology, Izmir, Turkey. bdoganavsargil@yahoo.com
authors.forename: Basak
authors.initials: B
authors.lastname: Doganavsargil
authors.forename: Ipek
authors.initials: I
authors.lastname: Akil
authors.forename: Sait
authors.initials: S
authors.lastname: Sen
authors.forename: Sevgi
authors.initials: S
authors.lastname: Mir
authors.forename: Gulcin
authors.initials: G
authors.lastname: Basdemir
mesh_terms: D002129:Calcium Oxalate / Q000378:metabolism*; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D007668:Kidney / Q000378:metabolism / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D008859:Microscopy, Polarization
chemical_list: D002129:Calcium Oxalate