title: Laser corneal biofilm disruption for infectious crystalline keratopathy.
abstract: Crystalline keratopathy can be successfully treated by the Nd:YAG laser. We present two cases of crystalline keratopathy managed this way. A 36-year-old female contact lens wearer presented with crystalline keratopathy following recent treatment with topical steroids and antibiotics for a corneal abscess. In this case crystalline keratopathy developed despite the intensive topical antibiotic treatment. A 55-year-old man with a history of acne rosacea, chronic myelomonocytic leukaemia, asthma and Crohn's disease presented with crystalline keratopathy following an episode of infectious keratitis. Treatment with the Nd:YAG laser to the area of involvement was instituted in both cases. Noticeable resolution occurred within days, with subsequent full recovery. No side-effects from the use of the Nd:YAG laser were noted. There have been only two cases previously reported using this treatment modality.
authors.affiliation: The Department of Ophthalmology, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Katherine
authors.initials: K
authors.lastname: Masselos
authors.forename: Hughie H C
authors.initials: HH
authors.lastname: Tsang
authors.forename: Ju-Lee
authors.initials: JL
authors.lastname: Ooi
authors.forename: Neil S
authors.initials: NS
authors.lastname: Sharma
authors.forename: Minas T
authors.initials: MT
authors.lastname: Coroneo
mesh_terms: D000328:Adult; D018441:Biofilms; D003316:Corneal Diseases / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D003319:Corneal Stroma / Q000382:microbiology / Q000601:surgery; D015818:Eye Infections, Bacterial / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology / Q000473:pathology / Q000601:surgery*