title: Safety of using iodized oil in chemoembolization for liver tumors in patients with previous adverse reactions to iodinated contrast media.
abstract: OBJECTIVE
  To evaluate the safety of using iodized oil in chemoembolization for liver tumors in patients with previous adverse reactions to iodinated contrast media.
  
  
  METHODS
  Records were retrospectively reviewed for all patients with a history of an adverse reaction to iodinated contrast media who underwent angiography using gadolinium-based contrast media and/or carbon dioxide at our institution from January 1998 to September 2006. Patients who underwent chemoembolization or hepatic artery infusion for liver tumors using iodized oil were identified.
  
  
  RESULTS
  There were 84 procedures with use of iodized oil performed in 36 patients. Mild adverse reactions potentially related to iodized oil were seen in two procedures (2.4%). There were no moderate or severe adverse reactions (0.0%).
  
  
  CONCLUSIONS
  Iodized oil can be safely used in patients with previous adverse reactions to iodinated contrast media.
authors.affiliation: Department of Radiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
authors.forename: Kanako
authors.initials: K
authors.lastname: Kunishima
authors.forename: Hidemasa
authors.initials: H
authors.lastname: Takao
authors.forename: Masaaki
authors.initials: M
authors.lastname: Akahane
authors.forename: Naoki
authors.initials: N
authors.lastname: Yoshioka
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000706:statistics & numerical data*; D003287:Contrast Media; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D005260:Female; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D007455:Iodine; D007459:Iodized Oil / Q000627:therapeutic use*; D007564:Japan / Q000453:epidemiology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D003287:Contrast Media; D006490:Hemostatics; D007459:Iodized Oil; D007455:Iodine