First synthesis of dimethyl-1H-isochromeno[3,4-b]carbazoles.
The first synthesis of isochromene fused carbazols, (4aS, 13bR)-2,5,5-trimethyl-3,4,4a,5,8,13b-hexahydroisochromeno[3,4-b]carbazole (2) and its epi-isomer 3 by condensation of citral and 2-hydroxycarbazole using Ti(OEt)4 and MeAlC12 as catalysts is described.
Cuong
Nguyen Manh
NM
Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Rd., Caugiay, Hanoi, Vietnam. nmcuong@ich.vast.ac.vn
Wilhelm
Heike
H
Porzel
Andrea
A
Wessjohann
Ludger
L
D001578:Benzopyrans / Q000138:chemical synthesis*; D002227:Carbazoles / Q000138:chemical synthesis*; D002384:Catalysis; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
D001578:Benzopyrans; D002227:Carbazoles; D007202:Indicators and Reagents