Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.
The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
Silvestre
Rodrigo Vellasco Duarte
RV
Departamento de Anatomia Patológica, Hospital Universitário João de Barros Barreto, Instituto de Ciências Biológicas, Universidade Federal do Pará, Campus Universitário do Guamá, 66075-900 Belém, PA, Brasil. .
Leal
Mariana Ferreira
MF
Demachki
Samia
S
Nahum
Márcia Cristina de Souza
MC
Bernardes
Julio Guilherme Balieiro
JG
Rabenhorst
Silvia Helena Barem
SH
Smith
Marília de Arruda Cardoso
Mde A
Mello
Wyller Alencar de
WA
Guimarães
Adriana Costa
AC
Burbano
Rommel Rodríguez
RR
D004279:DNA, Viral / Q000032:analysis; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000821:virology; D016133:Polymerase Chain Reaction; D011470:Prostatic Hyperplasia / Q000821:virology*; D011471:Prostatic Neoplasms / Q000821:virology*
D004279:DNA, Viral