Comparison of chronic-stage histopathological findings among 3 coronary stents implanted in the same patient.
A 73-year-old woman suffering from anterior thoracic pain on exertion presented to our hospital. We performed coronary angiography and noted three stenotic legions in each coronary artery. For each angiographic finding, we implanted a bare metal stent (BMS), sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) into the right coronary artery, left anterior descending and left circumflex coronary arteries, respectively. Nine months later, she died of lung disease, and we could compare the histopathological findings among the three coronary stents. In the drug-eluting stents, very thin intima, infiltration of inflammatory cells, and fibrin deposition were observed, while thick intima and no inflammatory findings were observed in the BMS. Fibrin deposition was more marked in the PES than in the SES. This report shows marked differences in the subsequent pathological course among three stents in the same patient.
Niki
Toshiyuki
T
Wakatsuki
Tetsuzo
T
Yamaguchi
Koji
K
Kusunose
Kenya
K
Koshiba
Kunihiko
K
Yagi
Shusuke
S
Taketani
Yoshio
Y
Iwase
Takashi
T
Tomita
Noriko
N
Yamada
Hirotsugu
H
Soeki
Takeshi
T
Akaike
Masashi
M
Sata
Masataka
M
D000368:Aged; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005260:Female; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage* / Q000009:adverse effects; D011859:Radiography; D020123:Sirolimus / Q000008:administration & dosage* / Q000009:adverse effects; D015607:Stents / Q000009:adverse effects
D017239:Paclitaxel; D020123:Sirolimus