[Effects of high volume hemofiltration on postoperative multiple organ dysfunction syndrome in severe abdominal infection patients].
OBJECTIVE
To evaluate the clinical efficacy of high-volume hemofiltration (HVHF) on treating postoperative multiple organ dysfunction syndrome in severe abdominal infection patients.


METHODS
Data of 17 severe abdominal infection patients treated with HVHF were collected and the differences on oxygenation indices, APACHE-II scores before and after HVHF therapy were observed.


RESULTS
After the first HVHF treatment, the oxygenation index improved, and the APACHE-II scores, TNF-alpha, IL-6, and IL-8 decreased significantly (P<0.05). After several HVHF treatments, the oxygenation index improved, and the APACHE-II scores decreased significantly (P<0.05).


CONCLUSIONS
HVHF can improve both the respiratory function and vital signs of severe sepsis patients and relieve the severity of the illness.
Yu
Zhi-ge
ZG
Department of General Surgery, General Hospital, Tianjin Medical University, Tianjin 300052, China.
Xu
Yi-lin
YL
Zhu
Li-wei
LW
D034841:Abdominal Cavity / Q000382:microbiology; D000368:Aged; D001424:Bacterial Infections / Q000150:complications*; D016207:Cytokines / Q000097:blood; D005260:Female; D006440:Hemofiltration; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000628:therapy*; D011183:Postoperative Complications / Q000628:therapy*
D016207:Cytokines