title: Ancestral RNA: the RNA biology of the eukaryotic ancestor.
abstract: Our knowledge of RNA biology within eukaryotes has exploded over the last five years. Within new research we see that some features that were once thought to be part of multicellular life have now been identified in several protist lineages. Hence, it is timely to ask which features of eukaryote RNA biology are ancestral to all eukaryotes. We focus on RNA-based regulation and epigenetic mechanisms that use small regulatory ncRNAs and long ncRNAs, to highlight some of the many questions surrounding eukaryotic ncRNA evolution.
authors.affiliation: Allan Wilson Centre for Molecular Ecology and Evolution, Institute for Molecular BioSciences, Massey University, Palmerston North, New Zealand.
authors.forename: Lesley J
authors.initials: LJ
authors.lastname: Collins
authors.forename: Xiaowei Sylvia
authors.initials: XS
authors.lastname: Chen
mesh_terms: D044127:Epigenesis, Genetic; D056890:Eukaryota; D019143:Evolution, Molecular; D012313:RNA / Q000235:genetics; D022661:RNA, Untranslated / Q000235:genetics*; D038621:Regulatory Sequences, Ribonucleic Acid
chemical_list: D022661:RNA, Untranslated; D038621:Regulatory Sequences, Ribonucleic Acid; D012313:RNA