[Pharmaceutical therapy for the severe hemodynamic depression with carotid artery stenting].
OBJECTIVE
To evaluate the efficacy of pharmaceutical therapy for the severe hemodynamic depression with carotid artery stenting(CAS).


METHODS
Clinical data were retrospectively analyzed on CAS over the last 5 years. Severe hemodynamic depression was defined as periprocedural hypotension (blood pressure <90/60 mmHg) or bradycardia (heart rate <50 beats/min) persisting for at least 1 hour. 13 patients were included in the research.


RESULTS
Dopamine was pumped intravenously in all the 13 patients .The dose was from 2 microg/min/kg to 10 microg/min/kg, the duration was from 4 to 48 hours. Dobutamine was used in 2 patients and dose from 5 microg/min/kg to 7 microg/min/kg, duration was from 24 to 36 hours. None of the patients developed any permanent neurological complications. One acute coronary syndrome occured during the postprocedure period.


CONCLUSIONS
Severe hemodynamic depression can be controlled with vasopressors (dopamine or dobutamine) and the associated complications can be prevented.
Yang
Min
M
Department of Intervention and Vascular Surgery, Peking University First Hospital, Beijing 100034, China.
Song
Li
L
Wang
Jian
J
Tong
Xiao-qiang
XQ
Zou
Ying-hua
YH
D000368:Aged; D000369:Aged, 80 and over; D001919:Bradycardia / Q000188:drug therapy* / Q000209:etiology; D016893:Carotid Stenosis / Q000628:therapy*; D004280:Dobutamine / Q000008:administration & dosage; D004298:Dopamine / Q000008:administration & dosage*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects*
D004280:Dobutamine; D004298:Dopamine