title: [Hemoaggregation dynamics in human-operator during percutaneous laser blood irradiation].
abstract: The experiment with essentially healthy male subjects no older than 50 involved functional load testing and irradiation by a low-energy helium-neon laser according to the standard therapeutic regimen (0.2 ml/V/ 30 min/10 sessions). Biomedical evaluation of hemoaggregation was made by 30 parameters of a multifunctional diagnostic system characterizing three blood aggregation levels: rheological (biophysical), coagulolytic (biochemical) and system (mathematical). The investigation resulted in delineation of a single-vector hypodynamic transformation of biophysical and biochemical modules, i.e. decrease in the rheological and coagulative potential mediated by a moderate platelets disaggregation (24.6%) and hyperactivation of plasmin proferments in euglobulin fraction (126.76 %). Added sessions of percutaneous laser irradiation of blood were shown to induce a medium imbalance of biophysical and biochemical hemoaggregation. At the same time, low-energy laser did not modulate significantly the general functional state of human operator as the rheological and coagulative protective potential of organism remained reasonably high (88.89 and 87.5 %, respectively).
authors.forename: L A
authors.initials: LA
authors.lastname: Subbotina
authors.forename: S N
authors.initials: SN
authors.lastname: Radchenko
authors.forename: O L
authors.initials: OL
authors.lastname: Golovkina
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Bubeev
mesh_terms: D001769:Blood / Q000528:radiation effects*; D001777:Blood Coagulation / Q000502:physiology / Q000528:radiation effects*; D001778:Blood Coagulation Disorders / Q000097:blood / Q000532:radiotherapy; D005500:Follow-Up Studies; D006801:Humans; D054020:Lasers, Gas / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000528:radiation effects*; D012016:Reference Values