title: Socio-demographic and clinical features of Irish iatrogenic hepatitis C patients: a cross-sectional survey.
abstract: BACKGROUND
  A discrete sub-group of iatrogenically-acquired hepatitis C virus (HCV)-infected individuals exists in the Irish population on whom limited current research data is available. The aim of this study was to establish a current profile of the socio-demographic and clinical characteristics of the Irish iatrogenic hepatitis C population and to determine factors predicting symptoms experienced.
  
  
  METHODS
  An anonymous, national, cross-sectional survey was conducted to explore this populations' self-reported health and social attributes. Data were collected on 290 respondents.
  
  
  RESULTS
  Mean time since infection was 26 years. Eighty-four percent (n = 237) of respondents were female (mean age = 55.9 +/- 9.6 years). Hepatic and extra-hepatic symptoms were common (62% and 99% respectively). Fatigue and pain were frequent complaints while 89% reported diagnosed co-morbid disease. On logistic regression, female gender, age and co-morbid disease emerged as independent predictors of self-reported symptoms.
  
  
  CONCLUSIONS
  This study describes the current status of the iatrogenically infected patient cohort in Ireland, adding to existing knowledge regarding the clinical course and consequences of HCV infection. Changing healthcare needs were shown by comparison with earlier surveys in this same population, in terms of disease progression, development of co-morbid disease and ageing.
authors.affiliation: UCD School of Physiotherapy and Performance Science, University College Dublin, Belfield, Dublin 4, Ireland. olivia.mckenna@hse.ie
authors.forename: Olivia
authors.initials: O
authors.lastname: McKenna
authors.forename: Caitriona
authors.initials: C
authors.lastname: Cunningham
authors.forename: Catherine
authors.initials: C
authors.lastname: Blake
mesh_terms: D000328:Adult; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004651:Employment; D005221:Fatigue / Q000523:psychology / Q000628:therapy; D005260:Female; D006305:Health Status Indicators; D016174:Hepacivirus / Q000502:physiology; D006526:Hepatitis C / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology* / Q000517:prevention & control; D007494:Ireland / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D020380:Needs Assessment; D010146:Pain / Q000523:psychology; D059408:Pain Management; D017678:Sex Distribution; D012923:Social Class; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013997:Time Factors