title: Science to practice: can an enzyme-sensitive MR contrast agent be used to image inflammation in aneurysms?
abstract: DeLeo et al have demonstrated in an animal model that inflammation associated with aneurysms can be evaluated noninvasively with magnetic resonance (MR) imaging and use of activatable contrast agents.
authors.affiliation: Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Harvard Medical School, 55 Fruit St, White 427, Boston, MA 02114, USA. umahmood@mgh.harvard.edu
authors.forename: Umar
authors.initials: U
authors.lastname: Mahmood
mesh_terms: D000818:Animals; D002340:Carotid Artery Diseases / Q000201:enzymology* / Q000473:pathology*; D017536:Carotid Artery, Common / Q000201:enzymology* / Q000473:pathology*; D002533:Cerebral Angiography; D003287:Contrast Media / Q000737:chemistry* / Q000494:pharmacology; D004108:Dilatation, Pathologic / Q000201:enzymology / Q000473:pathology; D004195:Disease Models, Animal; D019786:Gadolinium DTPA / Q000737:chemistry* / Q000494:pharmacology; D007089:Image Enhancement / Q000379:methods; D007249:Inflammation / Q000201:enzymology / Q000473:pathology; D002532:Intracranial Aneurysm / Q000201:enzymology* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009195:Peroxidase / Q000378:metabolism*; D011817:Rabbits
chemical_list: D003287:Contrast Media; D009195:Peroxidase; D019786:Gadolinium DTPA