Immune thrombocytopenia in children with reference to low-income countries.
Immune thrombocytopenia is a benign and self-limiting disorder. Data about the condition and its incidence from low-income countries is limited. This paper reviews the research about immune thrombocytopenia, comparing low- and high-income countries. Diagnosis is usually based on complete blood count and peripheral smear and, in selected cases, bone marrow aspiration. The disease has a high remission rate both in high- and low-income countries and intracranial haemorrhage is rare. The recommended treatment is simply observation of cases, especially when the platelet count is > 10,000 /mm3. If drug therapy is required, oral steroids are the most economical choice.
Rehman
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Bahawal Victoria Hospital, Bahawalpur, Pakistan. drarehman100@yahoo.com
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001856:Bone Marrow Examination; D015984:Causality; D002648:Child; D002675:Child, Preschool; D019049:Developed Countries / Q000706:statistics & numerical data; D003906:Developing Countries / Q000706:statistics & numerical data; D003937:Diagnosis, Differential; D014943:Global Health; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D015994:Incidence; D007223:Infant; D020300:Intracranial Hemorrhages / Q000453:epidemiology / Q000209:etiology; D010976:Platelet Count; D017410:Practice Guidelines as Topic; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012075:Remission, Spontaneous; D018029:Rho(D) Immune Globulin; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D018029:Rho(D) Immune Globulin