title: The mechanisms of failure of totally implantable central venous access system: analysis of 73 cases with fracture of catheter.
abstract: BACKGROUND
  Totally implantable access ports are often used for the administration of chemotherapy or prolonged intravenous infusions in patients with cancer. The technique has been well described. However, some complications would happen. The pinch-off-syndrome is one of these complications. We report another presentation of pinch-off-syndrome and how to prevent.
  
  
  METHODS
  From January 2005 to December 2007, 73 patients of catheter fracture were collected. The duration of Port-A implantation ranged from January 2003 to October 2007. During this period, 3358 port-catheters were implanted. There were three brands of Port-A implanted included 46% BardPort (Bard, Salt Lake City, UT, USA), 42% A Port (Arrow international, Reading, PA, USA) and 12% PORT-A CATH (Deltec, St. Paul, MN, USA).
  
  
  RESULTS
  The most common clinical presentation was difficulty in injection in 32 cases (43.8%). The incidence of brand C was far lower than brand A and B. The most common site of fracture was at the proximal part (anastomosis between injection port and catheter) in 68 cases (93.2%). The incidence of fracture of Port-A was 6 in 738 (0.81%) in cut-down method; 67 in 2620 (2.56%) in percutaneous subclavian method. Most of the cases (34%) were no more than six months.
  
  
  CONCLUSIONS
  The most frequent location of fracture Port-A was in proximal part - anastomosis between injection port and catheter. The cause of easily fracture may be associated with pinch-off-syndrome and design of Port-A. This kind of fracture could be prevented by cut-down method and fixed one stitch in proximal part.
authors.affiliation: Department of Surgery, Show Chwan Memorial Hospital, Changhua, Taiwan, ROC.
authors.forename: C H
authors.initials: CH
authors.lastname: Lin
authors.forename: H S
authors.initials: HS
authors.lastname: Wu
authors.forename: D C
authors.initials: DC
authors.lastname: Chan
authors.forename: C B
authors.initials: CB
authors.lastname: Hsieh
authors.forename: M H
authors.initials: MH
authors.lastname: Huang
authors.forename: J C
authors.initials: JC
authors.lastname: Yu
mesh_terms: D000328:Adult; D000368:Aged; D002405:Catheterization, Central Venous / Q000295:instrumentation*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D004867:Equipment Design; D004868:Equipment Failure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged