title: Surveillance programs for detection and characterization of emergent pathogens and antimicrobial resistance: results from the Division of Infectious Diseases, UNIFESP.
abstract: Several epidemiological changes have occurred in the pattern of nosocomial and community acquired infectious diseases during the past 25 years. Social and demographic changes possibly related to this phenomenon include a rapid population growth, the increase in urban migration and movement across international borders by tourists and immigrants, alterations in the habitats of animals and arthropods that transmit disease, as well as the raise of patients with impaired host defense abilities. Continuous surveillance programs of emergent pathogens and antimicrobial resistance are warranted for detecting in real time new pathogens, as well as to characterize molecular mechanisms of resistance. In order to become more effective, surveillance programs of emergent pathogens should be organized as a multicenter laboratory network connected to the main public and private infection control centers. Microbiological data should be integrated to guide therapy, adapting therapy to local ecology and resistance patterns. This paper presents an overview of data generated by the Division of Infectious Diseases, Federal University of São Paulo, along with its participation in different surveillance programs of nosocomial and community acquired infectious diseases.
authors.affiliation: Divisão de Doenças Infecciosas, Departamento de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brasil. colomboal@terra.com.br
authors.forename: Arnaldo L
authors.initials: AL
authors.lastname: Colombo
authors.forename: Mario
authors.initials: M
authors.lastname: Janini
authors.forename: Reinaldo
authors.initials: R
authors.lastname: Salomão
authors.forename: Eduardo A S
authors.initials: EA
authors.lastname: Medeiros
authors.forename: Sergio B
authors.initials: SB
authors.lastname: Wey
authors.forename: Antonio C C
authors.initials: AC
authors.lastname: Pignatari
mesh_terms: D001938:Brazil; D021821:Communicable Diseases, Emerging / Q000382:microbiology / Q000517:prevention & control / Q000821:virology; D017714:Community-Acquired Infections / Q000382:microbiology / Q000517:prevention & control / Q000821:virology; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control / Q000821:virology; D024881:Drug Resistance, Bacterial / Q000187:drug effects / Q000235:genetics; D025141:Drug Resistance, Fungal / Q000187:drug effects / Q000235:genetics; D024882:Drug Resistance, Viral / Q000187:drug effects / Q000235:genetics; D015497:HIV-1 / Q000187:drug effects / Q000235:genetics; D006785:Hospitals, University; D006801:Humans; D011159:Population Surveillance