[Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps].
OBJECTIVE
To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps.


METHODS
Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age.


RESULTS
Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps.


CONCLUSIONS
Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.
Dolgushin
I I
II
Andreeva
Iu S
IuS
Ryzhkova
A I
AI
Savochkina
A Iu
AIu
Mezentseva
E A
EA
Nikushkina
K V
KV
Abramovskikh
O S
OS
Marachev
S I
SI
Matveeva
D N
DN
D000328:Adult; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D009092:Mucous Membrane / Q000276:immunology; D009504:Neutrophils / Q000276:immunology* / Q000648:ultrastructure; D014621:Vagina / Q000276:immunology
D001428:Bacterial Vaccines; C039045:SolcoTrichovac