title: Ultrasonographic diagnosis of fetal structural abnormalities in prenatal screening at 11-14 weeks.
abstract: OBJECTIVE
  The aim of the study was to determine the detection rate of structural abnormalities at the 11-14 week ultrasound examination as a part of two-stage screening process in low-risk pregnancies.
  
  
  METHODS
  A total of 1085 consecutive low-risk pregnant women participated in screening by two-stage ultrasonography for the estimation of the sensitivity of the first and second trimester ultrasound scans in the detection of major anomalies as a part of routine screening.
  
  
  RESULTS
  Of 1085 pregnancies, 21 (1.93%) fetuses had at least one major structural defect considered detectable by routine ultrasound screening; 14 (1.29%) were identified at early screening and an additional 5 (0.47%) at late screening. Two abnormalities were not detected prenatally, and data were obtained from the patients after delivery.
  
  
  CONCLUSIONS
  The majority of fetal structural abnormalities can be detected by sonographic screening at 11-14 weeks, but detailed fetal anatomic survey performed at 18-22 weeks should not be abandoned.
authors.affiliation: Department of Radiology, Bozyaka Training and Research Hospital, Izmir, Turkey.
authors.forename: Ozgür
authors.initials: O
authors.lastname: Oztekin
authors.forename: Deniz
authors.initials: D
authors.lastname: Oztekin
authors.forename: Sivekar
authors.initials: S
authors.lastname: Tinar
authors.forename: Zehra
authors.initials: Z
authors.lastname: Adibelli
mesh_terms: D000028:Abortion, Induced; D002869:Chromosome Aberrations / Q000196:embryology*; D005260:Female; D006554:Hernia, Umbilical / Q000000981:diagnostic imaging / Q000196:embryology; D016142:Holoprosencephaly / Q000000981:diagnostic imaging / Q000196:embryology; D006801:Humans; D007621:Karyotyping; D011237:Predictive Value of Tests; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal