title: Impact of xerostomia on the quality of life of adolescents with type 1 diabetes mellitus.
abstract: OBJECTIVE
  To evaluate the impact of xerostomia on the quality of life (QOL) of adolescents with type 1 diabetes mellitus (DM1).
  
  
  METHODS
  The sample was comprised of 51 adolescents with DM1. Diabetic status was determined by glycosylated hemoglobin (HbG) and capillary glucose (CG) tests. Poor metabolic control was defined as HbG >8.0% and CG <90 mg/dL or >130 mg/dL. Measurement of salivary flow was performed by means of stimulated saliva collection. Xerostomia was detected by asking a question about the sensation of having "dry mouth," and OHIP-14 was used to measure the impact of xerostomia on QOL.
  
  
  RESULTS
  A total of 52.9% of subjects presented with xerostomia and 40.8% with hyposalivation. Significant differences between the subjects with and without xerostomia regarding metabolic control levels were not observed (P > .05). However, OHIP-14 scores were significantly different between the subjects with and without xerostomia (P < .001).
  
  
  CONCLUSIONS
  Xerostomia is frequent and has a negative impact on QOL of adolescents with DM1.
authors.affiliation: Postgraduate student, Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
authors.forename: Ivana Maria Saes
authors.initials: IM
authors.lastname: Busato
authors.forename: Sérgio Aparecido
authors.initials: SA
authors.lastname: Ignácio
authors.forename: João Armando
authors.initials: JA
authors.lastname: Brancher
authors.forename: Ana Maria Trindade
authors.initials: AM
authors.lastname: Grégio
authors.forename: Maria Angela Naval
authors.initials: MA
authors.lastname: Machado
authors.forename: Luciana Reis
authors.initials: LR
authors.lastname: Azevedo-Alanis
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D003430:Cross-Sectional Studies; D003679:Deglutition / Q000502:physiology; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000523:psychology*; D004326:Drinking / Q000502:physiology; D004435:Eating / Q000502:physiology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D011788:Quality of Life; D012463:Saliva / Q000378:metabolism; D012636:Secretory Rate / Q000502:physiology; D012917:Social Adjustment; D013060:Speech / Q000502:physiology; D013312:Stress, Physiological / Q000502:physiology; D013649:Taste / Q000502:physiology; D014987:Xerostomia / Q000503:physiopathology / Q000523:psychology*; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin