title: Retinal drusen: harbingers of age, safe havens for trouble.
abstract: Drusen are small focal extracellular deposits underneath the retina, visible ophthalmoscopically as yellow dots. The more hard drusen there are, the greater the risk of developing soft drusen and retinal pigmentary changes, which in turn increase the risk of developing advanced age-related macular degeneration. Much remains to be discovered about drusen. For the patient with drusen, basic advice on diet and smoking and maintenance of a high level of vigilance for visual changes is appropriate management.
authors.affiliation: Department of Geriatric Medicine, Whitla Medical Building, Queen's University of Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK. mikewilliams99@hotmail.com
authors.forename: M A
authors.initials: MA
authors.lastname: Williams
authors.forename: D
authors.initials: D
authors.lastname: Craig
authors.forename: P
authors.initials: P
authors.lastname: Passmore
authors.forename: G
authors.initials: G
authors.lastname: Silvestri
mesh_terms: D000375:Aging / Q000502:physiology; D018450:Disease Progression; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000503:physiopathology; D010857:Pigment Epithelium of Eye / Q000473:pathology; D015593:Retinal Drusen / Q000175:diagnosis / Q000503:physiopathology; D014792:Visual Acuity