title: Atractylis gummifera and Centaurea ornata in the Province of Badajoz (Extremadura, Spain)-Ethnopharmacological importance and toxicological risk.
abstract: BACKGROUND
  Atractylis gummifera L. and Centaurea ornata Willd. are locally marketed herbal remedies, even though in Spain it is forbidden to sell toxic plants like Atractylis gummifera. Intoxications in Spain are mainly due to accidental substitution of Centaurea ornata with Atractylis gummifera which may be fatal.
  
  
  OBJECTIVE
  The aim of this article is to analyse the current use and marketing of Atractylis gummifera and Centaurea ornata in Badajoz and analyse the ethnopharmacological relevance of two recent cases of Atractylis gummifera poisoning.
  
  
  METHODS
  An ethnopharmacological survey was conducted in the area where one of the poisoned patients lives and in Guadiana del Caudillo. The use, knowledge and naming of the species involved in the poisoning was assessed. This information was complemented with an exhaustive search in Spanish ethnobotanical works on the ethnopharmacological uses of both species.
  
  
  RESULTS
  Intoxications are due to species' substitutions. The two species are similar in name and use in the area, and both are locally marketed. AG is mainly used to heal wounds and calcaneal spurs, and CO to treat gastric ulcers and wounds.
  
  
  CONCLUSIONS
  New intoxications are likely since consumers often have limited knowledge of the plants they consume. Also, it is common to think that all medicinal plants are harmless. As the use of Atractylis gummifera seems to increase in the area, preventive measures need to be taken.
authors.affiliation: Grupo de Investigación en Humanidades Médicas, Facultad de Medicina, Universidad de Extremadura, 06071 Badajoz, Spain.
authors.forename: J R
authors.initials: JR
authors.lastname: Vallejo
authors.forename: D
authors.initials: D
authors.lastname: Peral
authors.forename: P
authors.initials: P
authors.lastname: Gemio
authors.forename: M C
authors.initials: MC
authors.lastname: Carrasco
authors.forename: M
authors.initials: M
authors.lastname: Heinrich
authors.forename: M
authors.initials: M
authors.lastname: Pardo-de-Santayana
mesh_terms: D036083:Atractylis / Q000506:poisoning*; D031179:Centaurea; D004340:Drug Contamination; D020834:Ethnopharmacology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008875:Middle Aged; D008517:Phytotherapy / Q000009:adverse effects / Q000706:statistics & numerical data; D010936:Plant Extracts / Q000506:poisoning*; D010947:Plants, Toxic / Q000506:poisoning; D013030:Spain
chemical_list: D010936:Plant Extracts