Mechanical properties and cytotoxicity of experimental soft lining materials based on urethane acrylate oligomers.
The purpose of this investigation was to determine whether experimental light-curing soft lining materials (ESLMs) based on commercially available urethane acrylate oligomers (UA-160TM, UV-3200B, UV-3500BA, and UV-3700B) are suitable for clinical use by measuring their viscosity, compressive modulus, Shore A hardness, tensile strength, adhesive strength, and cytotoxicity. The viscosities of the four ESLMs at 25 degrees C were 10.5 Pa.s, UV-3500BA; 144.0 Pa.s, UA-160TM; 328.8 Pa.s, UV-3700B; and 1079.7 Pa.s, UV-3200B. Polymerized UV-3700B was very soft, whereas the softness of the other ESLMs was similar to that of conventional soft lining materials. No significant difference in adhesive strength was observed between UV-3500BA and UV-3700B at 1 day and those at 12 months. Cytotoxicity was measured by a MTT-based assay using HeLa S3 and Ca9-22 cells. UV-3200B and UV-3700B oligomers and all four polymerized ESLMs showed cell viability over 95.2% (p < 0.05).
Kanie
Takahito
T
Department of Biomaterials Science, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan. einak@ms.kagoshima-u.ac.jp
Tomita
Koichi
K
Tokuda
Masayuki
M
Arikawa
Hiroyuki
H
Fujii
Koichi
K
Ban
Seiji
S
D000180:Acrylic Resins / Q000633:toxicity; D000268:Adhesiveness; D045744:Cell Line, Tumor / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D019245:Compressive Strength; D003799:Dental Stress Analysis; D003822:Denture Liners / Q000009:adverse effects; D006244:Hardness; D006801:Humans; D055115:Light-Curing of Dental Adhesives; D008422:Materials Testing; D011140:Polyurethanes / Q000633:toxicity; D013718:Tensile Strength; D014783:Viscosity
D000180:Acrylic Resins; D011140:Polyurethanes; C050845:urethane acrylate