title: [A case of primary small cell carcinoma of the esophagus responding remarkably to carboplatin (CBDCA) + etoposide (VP-16) combination therapy and radiation therapy].
abstract: A 78-year-old man was admitted to hour hospital because of dysphagia, and primary small cell carcinoma of the esophagus was diagnosed. Carboplatin (CBDCA) + etoposide (VP-16) combination chemotherapy and radiation therapy was performed. After this therapy, endoscopic examination and computed tomographic scan showed the disappearance of the primary esophageal tumor. Endoscopic examination with biopsy confirmed the disappearance of malignant cells. Severe adverse reactions were not observed during this therapy. This patient is alive without recurrence for 6 years and 3 months. This case seems to provide suggestions on deciding on the operative indications for small cell carcinoma of esophagus.
authors.affiliation: Division of Gastroenterology and Hepatology, The Jikei University Aoto Hospital. r-aizawa@jikei.ac.jp
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Aizawa
authors.forename: Kazuki
authors.initials: K
authors.lastname: Takakura
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Kubo
authors.forename: Kai
authors.initials: K
authors.lastname: Yoshizawa
authors.forename: Takuya
authors.initials: T
authors.lastname: Kitahara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Abe
authors.forename: Mika
authors.initials: M
authors.lastname: Matsuoka
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Aizawa
authors.forename: Hisao
authors.initials: H
authors.lastname: Tajiri
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D018288:Carcinoma, Small Cell / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008297:Male
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D005047:Etoposide; D016190:Carboplatin