title: Histology-based treatment of basal cell carcinoma.
abstract: Basal cell carcinoma is the most common type of skin cancer and its incidence is still rising. In recent years, new treatment modalities have been developed and existing modalities refined. The aim of this article is to give a histology-based overview of the available evidence-based research. The literature was searched for randomized controlled trials from which the efficacy of investigated treatments was obtained. Where possible, treatment modalities were evaluated specifically. Selection criteria were histological subtype, primary or recurrent basal cell carcinoma and tumour localization. Although surgery remains the preferred treatment for most basal cell carcinomas, patient and tumour characteristics should be taken into account when choosing the most suitable treatment.
authors.affiliation: Department of Dermatology, University Hospital Maastricht, Maastricht, The Netherlands. k.mosterd@mumc.nl
authors.forename: Klara
authors.initials: K
authors.lastname: Mosterd
authors.forename: Aimee H M M
authors.initials: AH
authors.lastname: Arits
authors.forename: Monique R T
authors.initials: MR
authors.lastname: Thissen
authors.forename: Nicole W J
authors.initials: NW
authors.lastname: Kelleners-Smeets
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002280:Basal Cell Carcinoma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D017679:Cryotherapy; D019317:Evidence-Based Medicine; D006801:Humans; D015580:Mohs Surgery; D009361:Neoplasm Invasiveness; D018579:Patient Selection; D010778:Photochemotherapy; D016032:Randomized Controlled Trials as Topic; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents