MR imaging of endometrial carcinoma for preoperative staging at 3.0 T: comparison with imaging at 1.5 T.
OBJECTIVE
To prospectively compare magnetic resonance imaging (MRI) at 3.0 T and 1.5 T in the same patients for preoperative evaluation of endometrial carcinoma.


METHODS
Thirty consecutive patients with endometrial carcinoma underwent MRI at both 3.0 T and 1.5 T as well as surgery. Quantitative and qualitative analyses were performed. Two radiologists independently evaluated images. MR findings were compared with surgicopathologic findings.


RESULTS
Image homogeneity of T2-weighted images at 3.0 T was significantly inferior to that at 1.5 T (P = 0.007). The scores of image homogeneity and susceptibility artifacts were not significantly different between 3.0 T gadolinium-enhanced imaging and 1.5 T imaging (P = 0.09 and 0.36). Kappa statistics showed good interobserver agreement between the two radiologists for local-regional staging on T2-weighted images (kappa>0.6). The area under the receiver operating characteristic curve (Az) values for T2-weighted imaging in terms of myometrial invasion, cervical invasion, and lymph node metastases were 0.88 (3.0 T) versus 0.91 (1.5 T), 0.84 versus 0.83, and 0.94 versus 0.95 for reader 1, respectively. There were no significant differences between imaging at 3.0 T and at 1.5 T in Az values for either reader (P > 0.35).


CONCLUSIONS
3.0 T MRI is an equivalent imaging modality to 1.5 T imaging for presurgical evaluation of endometrial carcinoma, although not significantly superior to 1.5 T imaging.
Hori
Masatoshi
M
Department of Radiology, Osaka University Graduate School of Medicine, Osaka, Japan. mhori@radiol.med.osaka-u.ac.jp
Kim
Tonsok
T
Murakami
Takamichi
T
Imaoka
Izumi
I
Onishi
Hiromitsu
H
Nakamoto
Atsushi
A
Nakaya
Yasuhiro
Y
Tomoda
Kaname
K
Tsutsui
Tateki
T
Enomoto
Takayuki
T
Kimura
Tadashi
T
Nakamura
Hironobu
H
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D019540:Area Under Curve; D016477:Artifacts; D018196:Carcinoma, Adenosquamous / Q000473:pathology* / Q000601:surgery; D003287:Contrast Media; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery; D004717:Endometrium / Q000473:pathology / Q000601:surgery; D005260:Female; D005682:Gadolinium; D006571:Heterocyclic Compounds; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D008875:Middle Aged; D009367:Neoplasm Staging; D015588:Observer Variation; D009942:Organometallic Compounds; D011300:Preoperative Care / Q000379:methods*; D011446:Prospective Studies; D015203:Reproducibility of Results
D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C062402:gadoteridol; D005682:Gadolinium