title: How well do pre- and peritransplant variables predict the long-term results of kidney transplantation?
abstract: In organ transplantation, several clinical risk factors that are available before or immediately following the time of surgery have been shown to affect long-term transplant outcomes. We examined their ability to predict long-term survival accurately using a novel statistical method and data from the Données Informatisees et Validées en Transplantation on 3,227 kidney transplant recipients between 1996-2006 at 5 French transplant centers. The results clearly illustrate that the correlation of these parameters with survival is not sufficient to constitute a prognostic marker. In kidney transplantation, classical pre- and peritransplant clinical risk factors of graft loss are poor predictive markers for medical decision-making.
authors.affiliation: ITERT IUN and INSERM U643, CHU de Nantes, Université de Nantes, France.
authors.forename: Yohann
authors.initials: Y
authors.lastname: Foucher
authors.forename: Pascal
authors.initials: P
authors.lastname: Daguin
authors.forename: Michèle
authors.initials: M
authors.lastname: Kessler
authors.forename: Marc
authors.initials: M
authors.lastname: Ladriere
authors.forename: Christophe
authors.initials: C
authors.lastname: Legendre
authors.forename: Henri
authors.initials: H
authors.lastname: Kreis
authors.forename: Dominique
authors.initials: D
authors.lastname: Durand
authors.forename: Laurence
authors.initials: L
authors.lastname: Laveyssiere
authors.forename: Georges
authors.initials: G
authors.lastname: Mourad
authors.forename: Valérie
authors.initials: V
authors.lastname: Garrigue
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Soulillou
authors.forename: Magali
authors.initials: M
authors.lastname: Giral
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006084:Graft Rejection / Q000209:etiology / Q000517:prevention & control*; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011237:Predictive Value of Tests; D012372:ROC Curve; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D017211:Treatment Failure; D055815:Young Adult