title: Current bacteriology of chronic otitis media with effusion: high rate of nosocomial infection and decreased antibiotic sensitivity.
abstract: OBJECTIVE
  Otitis media with effusion is a common disease entity in children, which is frequently managed surgically by insertion of a tympanostomy tube. Children who develop posttympanostomy tube otorrhea (PTTO) can be treated by administration of antibiotics. The abuse and misuse of antibiotics, however, has led to the emergence of resistant bacterial strains. We therefore examined the antibiotic sensitivity of bacterial strains collected from middle ear effusion fluid (MEEF) and PTTO. We also evaluated treatment outcomes in these patients.
  
  
  METHODS
  This study was conducted in 289 patients who underwent tympanostomy tube insertion for chronic otitis media with effusion between March 2004 and February 2008.
  
  
  RESULTS
  Bacterial culture tests during the insertion of tympanostomy tubes showed a high frequency of coagulase(-) Staphylococcus (CNS), followed by Pseudomonas, methicillin resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA). Patients with PTTO had a high frequency of CNS and MRSA, followed by MSSA and Streptococcus pneumoniae. Overall antibiotic sensitivity was lower in postoperatively collected than in intraoperatively collected bacterial strains.
  
  
  CONCLUSIONS
  The bacterial strains detected in MEEF, and their antibiotic sensitivity profiles, differed somewhat from those of PTTO. Antibiotic sensitivity was decreased in bacteria from PTTO compared with those in MEEF.
authors.affiliation: Department of Otolaryngology, College of Medicine, Kyung Hee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul, Republic of Korea.
authors.forename: Hoon
authors.initials: H
authors.lastname: Jung
authors.forename: Sun Kyu
authors.initials: SK
authors.lastname: Lee
authors.forename: Sung-Ho
authors.initials: SH
authors.lastname: Cha
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Byun
authors.forename: Moon Suh
authors.initials: MS
authors.lastname: Park
authors.forename: Seung Geun
authors.initials: SG
authors.lastname: Yeo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D008876:Middle Ear Ventilation / Q000009:adverse effects / Q000706:statistics & numerical data; D010034:Otitis Media with Effusion / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery; D011183:Postoperative Complications / Q000382:microbiology; D011549:Pseudomonas / Q000302:isolation & purification; D013210:Staphylococcus / Q000302:isolation & purification; D013211:Staphylococcus aureus / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents