Iridium-catalyzed coupling reaction of primary alcohols with 1-aryl-1-propynes leading to secondary homoallylic alcohols.
We report iridium-catalyzed coupling of 2-alkynes such as 1-aryl-1-propynes with primary alcohols leading to secondary homoallylic alcohols as products. This reaction involves an iridium-catalyzed novel catalytic transformation of 2-alkynes and primary alcohols through the formation of hydrido(pi-allyl)iridium as a possible key intermediate.
Obora
Yasushi
Y
Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, High Technology Research Center, and ORDIST, Kansai University, Suita, Osaka 564-8680, Japan. obora@ipcku.kansai-u.ac.jp
Hatanaka
Shintaro
S
Ishii
Yasutaka
Y