title: Photo-polymeriable chitosan derivative prepared by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA).
abstract: N-Alkyled photo-polymeriable chitosan derivative (PEGDA-CS) was synthesized by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA) under mild reaction conditions. The chemical structure and physical properties of PEGDA-CS were characterized by FT-IR, (1)H NMR, XRD and TG techniques. The degree of substitution (DS) of PEGDA-CS could be calculated from (1)H NMR. PEGDA-CS exhibited good solubility in distilled water. XRD analysis showed that PEGDA-CS was amorphous. TG results demonstrated that thermal stability of the derivate was lower than that of chitosan. Antimicrobial test showed that PEGDA-CS had the antimicrobial activity on Escherichia coli. It could photopolymerize under ultraviolet light with 2959 as initiator.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang, Beijing 100029, PR China.
authors.forename: Guiping
authors.initials: G
authors.lastname: Ma
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Han
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Song
authors.forename: Jun
authors.initials: J
authors.lastname: Nie
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D002625:Chemistry, Organic / Q000379:methods; D048271:Chitosan / Q000737:chemistry*; D004926:Escherichia coli / Q000378:metabolism; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008956:Models, Chemical; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013818:Thermogravimetry / Q000379:methods; D014466:Ultraviolet Rays; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D011108:Polymers; C437167:poly(ethylene glycol)diacrylate; D014867:Water; D011092:Polyethylene Glycols; D048271:Chitosan