title: Facile formation of dehydroalanine from S-nitrosocysteines.
abstract: A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.
authors.affiliation: Department of Chemistry, Washington State University, Pullman, Washington 99164, USA.
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Jiming
authors.initials: J
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Xian
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000737:chemistry; D002384:Catalysis; D003545:Cysteine / Q000031:analogs & derivatives* / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry; D026403:S-Nitrosothiols / Q000737:chemistry*
chemical_list: D010720:Phosphines; D026403:S-Nitrosothiols; C021315:S-nitrosocysteine; C015102:dehydroalanine; C044646:phosphine; D003545:Cysteine; D000409:Alanine