title: [Cochlear implantation in patients with large vestibular aqueduct syndrome].
abstract: OBJECTIVE
  To evaluate the hearing and speech recognition in patients with large vestibular aqueduct syndrome undergoing multi-channel cochlear implantation.
  
  
  METHODS
  From 2005 to 2008, multi-channel cochlear implantation surgeries were performed in 22 patients with large vestibular aqueduct syndrome. All the patients received multi-channel cochlear implantation through transmastoid facial recess approach. The postoperative outcomes of the patients were compared with those of 22 patients with non-malformed cochlear.
  
  
  RESULTS
  Severe gusher occurred in 3 cases during the implantation, and perilymph fluctuation was found in another 15 cases, with a rate of anomalies of 81.8%. All the electrodes were totally inserted into the cochlear, and no facial paralysis or cerebrospinal fluid leakage occurred after the operation. The hearing threshold in these patients was similar to that in patients with normal cochlear receiving the implantation. After speech rehabilitation for over 6 months, all the patients showed improved hearing and verbal ability.
  
  
  CONCLUSIONS
  Multi-channel cochlear implantation can be performed in patients with large vestibular aqueduct syndrome, but preoperative hearing assessment and radiographic examinations should be performed.
authors.affiliation: Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. wanliangcai@126.com
authors.forename: Liang-cai
authors.initials: LC
authors.lastname: Wan
authors.forename: Meng-he
authors.initials: MH
authors.lastname: Guo
authors.forename: Yu-hong
authors.initials: YH
authors.lastname: Qian
authors.forename: Shuang-xiu
authors.initials: SX
authors.lastname: Liu
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Jian
authors.initials: J
authors.lastname: Gong
authors.forename: Shuai-jun
authors.initials: SJ
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D004566:Electrodes; D005260:Female; D006309:Hearing; D034381:Hearing Loss / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D013060:Speech; D014057:Tomography, X-Ray Computed; D014723:Vestibular Aqueduct / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D055815:Young Adult