Safety of using iodized oil in chemoembolization for liver tumors in patients with previous adverse reactions to iodinated contrast media.
OBJECTIVE
To evaluate the safety of using iodized oil in chemoembolization for liver tumors in patients with previous adverse reactions to iodinated contrast media.


METHODS
Records were retrospectively reviewed for all patients with a history of an adverse reaction to iodinated contrast media who underwent angiography using gadolinium-based contrast media and/or carbon dioxide at our institution from January 1998 to September 2006. Patients who underwent chemoembolization or hepatic artery infusion for liver tumors using iodized oil were identified.


RESULTS
There were 84 procedures with use of iodized oil performed in 36 patients. Mild adverse reactions potentially related to iodized oil were seen in two procedures (2.4%). There were no moderate or severe adverse reactions (0.0%).


CONCLUSIONS
Iodized oil can be safely used in patients with previous adverse reactions to iodinated contrast media.
Kunishima
Kanako
K
Department of Radiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Takao
Hidemasa
H
Akahane
Masaaki
M
Yoshioka
Naoki
N
Ohtomo
Kuni
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000706:statistics & numerical data*; D003287:Contrast Media; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D005260:Female; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D007455:Iodine; D007459:Iodized Oil / Q000627:therapeutic use*; D007564:Japan / Q000453:epidemiology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
D003287:Contrast Media; D006490:Hemostatics; D007459:Iodized Oil; D007455:Iodine