Primary cutaneous aspergillosis due to Aspergillus niger in an immunocompetent patient.
Primary cutaneous aspergillosis is a rare entity, usually caused by A. fumigatus and A. flavus . Here, we present such a case, manifested by ulceration due to A. niger, which remained undiagnosed for a prolonged period. The immunological status was intact, although the patient had associated severe fungal infection. Recurrence of the lesion occurred despite repeated anti-fungal therapies. Anti fungal testing was done based on the broth dilution (M-38A, NCCLS, USA) method. The culture isolate was found to be sensitive to fluconazole and amphotericin B. Continuation of antifungal therapy improved the symptoms, reducing the size of the lesion.
Mohapatra
S
S
Department of Microbiology, All India Institute of Medical Sciences, New Delhi - 110 029, India.
Xess
I
I
Swetha
J V
JV
Tanveer
N
N
Asati
D
D
Ramam
M
M
Singh
M K
MK
D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D001234:Aspergillus niger / Q000302:isolation & purification*; D003881:Dermatomycoses / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D012008:Recurrence; D012883:Skin Ulcer / Q000382:microbiology / Q000473:pathology
D000935:Antifungal Agents