title: Microtubule-dependent cell morphogenesis in the fission yeast.
abstract: In many systems, microtubules contribute spatial information to cell morphogenesis, for instance in cell migration and division. In rod-shaped fission yeast cells, microtubules control cell morphogenesis by transporting polarity factors, namely the Tea1-Tea4 complex, to cell tips. This complex then recruits the DYRK kinase Pom1 to cell ends. Interestingly, recent work has shown that these proteins also provide long-range spatial cues to position the division site in the middle of the cell and temporal signals to coordinate cell length with the cell cycle. Here I review how these microtubule-associated proteins form polar morphogenesis centers that control and integrate both spatial and temporal aspects of cell morphogenesis.
authors.affiliation: Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Génopode Building, 1015 Lausanne, Switzerland. sophie.martin@unil.ch
authors.forename: Sophie G
authors.initials: SG
authors.lastname: Martin
mesh_terms: D002455:Cell Division; D006801:Humans; D008870:Microtubules / Q000378:metabolism*; D011485:Protein Binding; D021381:Protein Transport; D012568:Schizosaccharomyces / Q000166:cytology* / Q000254:growth & development / Q000378:metabolism*; D029702:Schizosaccharomyces pombe Proteins / Q000378:metabolism*
chemical_list: D029702:Schizosaccharomyces pombe Proteins