HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a patient with systemic lupus erythematosus and antiphospholipid syndrome.
We report a case of HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a woman in the 17th week of pregnancy with SLE and APS who had been in remission on a regimen of low-dose prednisolone and aspirin. An increase in the dosage of corticosteroid together with intravenous heparin infusion led to improvement of the clinical symptoms, laboratory parameters, and multifocal low-density liver lesions detected by computed tomography. Early onset and signs of severe organ involvement are the characteristic features of HELLP syndrome associated with APS, and patients that are at risk should be followed up carefully.
Wada
Yoko
Y
Clinical Nephrology and Rheumatology, Department of Medicine II, Niigata University Graduate School of Medical and Dental Sciences, Niigata. yoko.wada@gmail.com
Sakamaki
Yuichi
Y
Kobayashi
Daisuke
D
Ajiro
Junya
J
Moro
Hiroshi
H
Murakami
Shuichi
S
Ooki
Izumi
I
Kikuchi
Akira
A
Takakuwa
Koichi
K
Tanaka
Kenichi
K
Sato
Takehiro
T
Nakano
Masaaki
M
Narita
Ichiei
I
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005313:Fetal Death / Q000175:diagnosis*; D017359:HELLP Syndrome / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000175:diagnosis*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*