title: Sensitive label-free and compact biosensor based on concentric silicon-on-insulator microring resonators.
abstract: We propose an ultracompact parallel label-free biosensor based on concentric silicon-on-insulator microring resonators. Our numerical studies show that the proposed biosensor offers higher sensitivity and a larger detection area than conventional single-ring-based sensors. We analyze the detection sensitivity of the DNA hybridization by immobilizing the probe on top of the double concentric ring resonators and in the ring-ring air gap. For a concentric double-ring system with an area of 27.646 microm2, the bulk detection sensitivity is 683 nm RIU(-1). The sensitive uniformity of the system related to the optical field distribution is also studied.
authors.affiliation: Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Li
authors.forename: Ziyang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Shenying
authors.initials: S
authors.lastname: Qin
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Fangfei
authors.initials: F
authors.lastname: Liu
authors.forename: Min
authors.initials: M
authors.lastname: Qiu
authors.forename: Yikai
authors.initials: Y
authors.lastname: Su
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation*; D008904:Miniaturization; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012825:Silicon / Q000737:chemistry*; D013194:Staining and Labeling; D014159:Transducers; D014732:Vibration
chemical_list: D012825:Silicon