title: Growth factors and corneal epithelial wound healing.
abstract: In this article, we briefly review recent findings in the effects of growth factors including the EGF family, KGF, HGF, IGF, insulin, and TGF-beta on corneal epithelial wound healing. We discuss the essential role of EGFR in inter-receptor cross-talk in response to wounding in corneal epithelium and bring forward a concept of "alarmins" to the field of wound healing research.
authors.affiliation: Kresge Eye Institute, Departments of Ophthalmology and Anatomy and Cell Biology, Wayne State University School of Medicine, 4717 St. Antoine Blvd., Detroit, MI, 48201, USA. fyu@med.wayne.edu
authors.forename: Fu-Shin X
authors.initials: FS
authors.lastname: Yu
authors.forename: Jia
authors.initials: J
authors.lastname: Yin
authors.forename: Keping
authors.initials: K
authors.lastname: Xu
authors.forename: Jenny
authors.initials: J
authors.lastname: Huang
mesh_terms: D000818:Animals; D003316:Corneal Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D019573:Epithelium, Corneal / Q000503:physiopathology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000145:classification / Q000502:physiology*; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
chemical_list: D036341:Intercellular Signaling Peptides and Proteins