Familial hypercholesterolaemia: different perspectives.
Familial hypercholesterolaemia is a genetic condition characterised by high cholesterol levels in the blood and an increased risk of premature coronary heart disease. In this article, the authors review the clinical features, pathology, epidemiology and clinical management of this often underdiagnosed condition.
Jones
Jane L
JL
Royal Brompton and Harefield NHS Trust, Middlesex.
Lakasing
Edin
E
Archontakis
Stefanos
S
D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001384:Azetidines / Q000627:therapeutic use; D008078:Cholesterol, LDL / Q000235:genetics; D000069438:Ezetimibe; D005799:Genes, Dominant; D006579:Heterozygote; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006938:Hyperlipoproteinemia Type II / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics; D009154:Mutation; D011973:Receptors, LDL / Q000235:genetics
D000924:Anticholesteremic Agents; D001384:Azetidines; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011973:Receptors, LDL; D000069438:Ezetimibe