title: Primary renal lymphoma: report of three new cases and literature review.
abstract: OBJECTIVE
  We report the cases of three patients with primary renal lymphoma. Diagnosis and subsequent treatment are discussed.
  
  
  METHODS
  The literature on the origin, epidemiology, clinical presentation, diagnosis, treatment and prognosis of primary renal lymphoma was reviewed.
  
  
  RESULTS
  The first patient was diagnosed after radical nephrectomy and subsequently was given six cycles of CVP (cyclophosphamide, vincristine, prednisone). The diagnosis of the second patient was established by renal biopsy, and the patient received six cycles of CHOP (cyclophosphamide, adriamycin, vincristine and predisone). The last patient had a lymphoma, secondary to immunosuppression, in a transplanted kidney. In this case transplant nephrectomy sufficed to cure the patient's lymphoma. All patients had B-cell non-Hodgkin lymphoma (an extrarenal origin was ruled out by bone marrow biopsy), and were disease-free 15 months, 7 months, and 6.5 years after diagnosis, respectively.
  
  
  CONCLUSIONS
  Primary renal lymphoma is rare. Diagnosis is established by renal biopsy, although it often presents as a mass simulating renal cell cancer and diagnosis is obtained after radical nephrectomy. Treatment consists of chemotherapy (CHOP). associated with rituximab.
authors.affiliation: Department of Urology, University Hospital Virgen de las Nieves, Granada, Spain. fernando.vazquez.alonso.sspa@juntadeandalucia.es
authors.forename: Fernando
authors.initials: F
authors.lastname: Vázquez Alonso
authors.forename: Carolina
authors.initials: C
authors.lastname: Sánchez Ramos
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Vicente Prados
authors.forename: Manrique
authors.initials: M
authors.lastname: Pascual Geler
authors.forename: Eduardo
authors.initials: E
authors.lastname: Ruiz Carazo
authors.forename: Patricia
authors.initials: P
authors.lastname: Becerra Massare
authors.forename: Carlos
authors.initials: C
authors.lastname: Funes Padilla
authors.forename: Francisco
authors.initials: F
authors.lastname: Rodríguez Herrera
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Cózar Olmo
authors.forename: Miguel
authors.initials: M
authors.lastname: Tallada Buñuel
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000628:therapy; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged