Probe for i-motif structure and G-rich strands using end-stacking ability.
We suggest a novel method for probing human i-motif structure based on a pi-stacking interaction between a base pair of two cytosines and a non-polar aromatic fluorophore, PyA, at the end position.
Lee
Il Joon
IJ
Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, South Korea.
Yi
Jeong Wu
JW
Kim
Byeang Hyean
BH
D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D003839:Deoxyadenosines / Q000138:chemical synthesis / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D020862:GC Rich Sequence; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D011721:Pyrenes / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D016615:Telomere / Q000737:chemistry; D044366:Transition Temperature
D004277:DNA, Single-Stranded; D003839:Deoxyadenosines; D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D011721:Pyrenes; D004247:DNA; C030984:pyrene