title: Cases of pediatric ingestion of celecoxib reported to Texas poison control centers in 2000-2007.
abstract: Little data exist regarding pediatric celecoxib ingestions. This study described the pattern of pediatric celecoxib ingestions reported to poison control centers. Cases were isolated celecoxib ingestions by patients aged 0-5 years during 2000-2007 reported to Texas poison control centers. The distribution of cases was described with respect to demographic and clinical factors. Of the 177 total patients, dose ingested in milligrams was reported for 92 patients. Mean reported dose was 305.5 mg (range 10-2300 mg). Of those 92 cases, distribution by management site was 89.1% on site, 6.5% already at/en route to healthcare facility and 4.3% referred to healthcare facility. Final medical outcome was no effect for 95.7% cases and minor effect for 4.3% cases. Specific clinical effects reported (in only one case each) were rash, abdominal pain, vomiting, agitation/irritability, and drowsiness. All of the pediatric celecoxib ingestions reported to Texas poison control centers resulted in no or minor effect.
authors.affiliation: Epidemiology and Disease Surveillance Unit, Texas Department of State Health Services, Austin, Texas 78756, USA. mathias.forrester@dshs.state.tx.us
authors.forename: M B
authors.initials: MB
authors.lastname: Forrester
mesh_terms: D000367:Age Factors; D000068579:Celecoxib; D002675:Child, Preschool; D052246:Cyclooxygenase 2 Inhibitors / Q000009:adverse effects / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011039:Poison Control Centers; D011041:Poisoning / Q000453:epidemiology; D011720:Pyrazoles / Q000009:adverse effects / Q000506:poisoning*; D013449:Sulfonamides / Q000009:adverse effects / Q000506:poisoning*; D013781:Texas / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D011720:Pyrazoles; D013449:Sulfonamides; D000068579:Celecoxib