title: Local complications after cosmetic breast augmentation: results from the Danish Registry for Plastic Surgery of the breast.
abstract: BACKGROUND
  Prospective long-term data on the occurrence of complications following breast augmentation are sparse and the reported frequencies differ substantially.
  
  
  METHODS
  The Danish Registry for Plastic Surgery of the Breast has prospectively registered preoperative, perioperative, and postoperative data for women undergoing breast augmentation in Denmark since 1999. From the Registry, the authors identified 5373 women with a primary cosmetic breast augmentation between 1999 and 2007. The authors calculated incidence proportions of adverse clinical outcomes within three time intervals (0 to 30 days, 0 to 3 years, and 0 to 5 years) after primary implantation. Outcomes of primary interest were capsular contracture, asymmetry/displacement of the implant, hematoma, and infection.
  
  
  RESULTS
  During the entire follow-up period (mean, 3.8 years; range, 0.1 to 8.7 years), 16.7 percent of the women were registered with an adverse event and 4.8 percent of the women were registered with a surgery-requiring complication. The most common adverse events within 30 days were hematoma (1.1 percent) and infections (1.2 percent), whereas the most common adverse events within 5 years were change of tactile sense (8.7 percent) and asymmetry/displacement of implant (5.2 percent). Within 5 years, 1.7 percent of the women had a record of severe capsular contracture. Displacement/asymmetry and capsular contracture were the most frequent indications for reoperation with removal or exchange of the implant.
  
  
  CONCLUSIONS
  Population-based complication frequencies among women with cosmetic breast augmentation in a Danish nationwide implant registry were generally lower than those reported in other studies, although frequencies of complications increased with length of follow-up.
authors.affiliation: Copenhagen, Herlev, and Roskilde, Denmark; Rockville, Md.; and Nashville, Tenn. From the Institute of Cancer Epidemiology, Danish Cancer Society; the Danish Registry for Plastic Surgery of the Breast; the Department of Plastic Surgery, Herlev University Hospital; the Department of Plastic Surgery, Roskilde Hospital; the International Epidemiology Institute; and the Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center.
authors.forename: Gitte B
authors.initials: GB
authors.lastname: Hvilsom
authors.forename: Lisbet R
authors.initials: LR
authors.lastname: Hölmich
authors.forename: Trine F
authors.initials: TF
authors.lastname: Henriksen
authors.forename: Loren
authors.initials: L
authors.lastname: Lipworth
authors.forename: Joseph K
authors.initials: JK
authors.lastname: McLaughlin
authors.forename: Søren
authors.initials: S
authors.lastname: Friis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019928:Breast Implantation / Q000009:adverse effects*; D018427:Breast Implants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects*; D008875:Middle Aged; D055815:Young Adult