Therapeutic failure in a renal transplant patient with Pneumocystis jiroveci pneumonia: a case report.
OBJECTIVE
Pneumocystis jiroveci pneumonia is common in immunocompromised individuals.


METHODS
This case report describes an immunosuppressed patient who acquired P jiroveci pneumonia 6 months after renal transplant surgery.


RESULTS
The patient experienced many pneumonia-related complications and adverse effects from drug therapy, and despite treatment with various antibiotic agents, he died on the 62nd day after his admission to the intensive care unit.


CONCLUSIONS
The therapeutic failure of the drug of choice (co-trimoxazole) was evident. This case raises questions about the development of P jiroveci resistance to current therapies.
Archontoulis
Nikolaos K
NK
Intensive Care Unit, Laiko General Hospital, Aretaieio Hospital, 11528 Athens, Greece.
Staikou
Chryssoula V
CV
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D045363:Pneumocystis carinii / Q000472:pathogenicity*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000276:immunology; D017211:Treatment Failure; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination