title: Synthetic graft use in vaginal prolapse surgery: objective   and subjective outcomes.
abstract: OBJECTIVE
  This study reports 1-year outcomes in women who underwent transvaginal pelvic organ prolapse (POP) surgery with Prolift transvaginal mesh.
  
  
  METHODS
  Pre- and postoperative objective vaginal Pelvic Organ Prolapse Quantification (POP-Q) and subjective symptom and impact assessments (Pelvic Floor Distress Inventory (PFDI)-20 and Pelvic Floor Impact Questionnaire (PFIQ)-7, respectively) were performed. Postoperative vaginal tenderness, stricture, and patient satisfaction were also obtained. Paired t tests were utilized for analysis.
  
  
  RESULTS
  Mean age was 61.8 +/- 9.8 years; mean follow-up interval was 425.0 +/- 80.0 days (range, 237-717). POP-Q measurements of Ba, Bp, and C were significantly improved (all p values <or= 0.001). PFDI and PFIQ subscale scores significantly improved (all p values <or= 0.004). Thirty-five of 48 (73%) were completely satisfied, and two (4%) were not satisfied. Complications (n (percent)) included graft exposure (1 (2%)), dyspareunia (2 (4%)), and granulation tissue (3 (6%)).
  
  
  CONCLUSIONS
  Women undergoing transvaginal repair of POP with the Prolift mesh system showed significant improvement in 1-year anatomic and subjective measures.
authors.affiliation: Division of Women's Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, AL, USA.
authors.forename: Luisa A
authors.initials: LA
authors.lastname: Wetta
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Gerten
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Wheeler
authors.forename: Robert L
authors.initials: RL
authors.lastname: Holley
authors.forename: R Edward
authors.initials: RE
authors.lastname: Varner
authors.forename: Holly E
authors.initials: HE
authors.lastname: Richter
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D006306:Health Surveys; D006801:Humans; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D012189:Retrospective Studies; D053825:Suburethral Slings / Q000009:adverse effects; D013526:Surgical Mesh / Q000009:adverse effects; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*