title: [Examination of accuracy and factors influencing optical coherence tomography(OCT)measurements].
abstract: BACKGROUND
  Optical coherence tomography (OCT) is a new imaging modality with increasing clinical application. In the present study, we examined the accuracy and factors influencing the OCT measurements (luminal diameter, area, and stent strut thickness).
  
  
  METHODS
  We evaluated several luminal sizes of phantom model by OCT with several situations (frame-rate: 8.2 or 15.6 F/s; pullback-speed: 1.0 or 2.0 mm/s; position of Image Wire: in-center; off-center) and compared them with the actual value and the intravascular ultrasound measurements. We also evaluated the accuracy of the stent strut thickness (5 bare metal stents and 2 drug eluting stents) in stents that were implanted to phantom models.
  
  
  RESULTS
  The accuracy of OCT measurements was affected by frame-rate and the position of OCT Image Wire. The distortion and the change in brightness of the OCT image were detected when the Image Wire was positioned off-center, especially at low frame-rate. In this condition, OCT measured the luminal diameter and area larger than the actual size. As for the strut thickness, when we unified the measurement points of the stent strut surface, the precision of the OCT measurements was satisfactory.
  
  
  CONCLUSIONS
  We revealed that the precision of the OCT measurements was satisfactory. However, we should note that the OCT measurements were affected by frame-rate and position of the Image Wire.
authors.affiliation: Department of Radiology, Kobe University Hospital.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Negi
authors.forename: Masanobu
authors.initials: M
authors.lastname: Koto
authors.forename: Junya
authors.initials: J
authors.lastname: Shite
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sawada
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kawamitsu
mesh_terms: D019047:Phantoms, Imaging; D015607:Stents; D041623:Tomography, Optical Coherence / Q000592:standards*