Recent progress in luteinizing hormone/human chorionic gonadotrophin hormone research.
The role of luteinizing hormone (LH) and human chorionic gonadotrophin hormone (hCG) in the regulation of normal reproductive functions in males and females is quite well established. Besides the use of hCG in the development of diagnostic immunoassays, it has been successfully used in the induction of final follicular maturation and ovulation in the assisted reproductive technologies. The basic and clinical research on the nongonadal actions of LH/hCG in the recent years has extended the potential of using these hormones in several clinical indications. Hereby we will analyze the advances in the LH/hCG research (briefly emphasizing the nongonadal research), which has the potential for multiple novel therapies in reproductive and the other areas of medicine.
Rahman
Nafis A
NA
Department of Physiology, Faculty of Medicine, Institute of Biomedicine, University of Turku, FIN-20520 Turku, Finland. nafis.rahman@utu.fi
Rao
C V
CV
D006063:Chorionic Gonadotropin / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D008297:Male; D010062:Ovulation Induction; D012098:Reproduction / Q000502:physiology; D027724:Reproductive Techniques, Assisted / Q000639:trends
D006063:Chorionic Gonadotropin; D007986:Luteinizing Hormone