title: Blocking leukotrienes optimize asthma control: the BLOC survey.
abstract: OBJECTIVE
  The aim of this study was to evaluate asthma control after the introduction of a leukotriene modifier (Montelukast), in addition to the current controller asthma therapies, in patients with inadequately controlled mild-to-moderate persistent asthma. Asthma control and patient perception were assessed prior to, and 4 weeks after, the introduction of Montelukast, and the pre-introduction and post-introduction results were compared.
  
  
  METHODS
  A cross-sectional, observational study collected information on 1,490 eligible adult asthmatic patients in Saudi Arabia. The eligibility criteria included patients aged 15 years or more with symptomatic mild-to-moderate persistent asthma despite treatment with inhaled corticosteroids with or without long-acting beta agonist; also, the patient should attend the initial visit and follow-up visits after at least 4 weeks.
  
  
  RESULTS
  Of the 1,490 eligible patients, 79.5% received inhaled corticosteroids alone, and the remaining 20.5% received combination of inhaled corticosteroids and long-acting bronchodilator. Despite the treatment with daily controller medications, asthma symptoms persisted in more than two-thirds of the study population. Upon adding Montelukast, more than 80% of patients reported improvement in symptoms, which was consistent in all patients irrespective of corticosteroid type or dose (stratum) or the addition of long-acting beta2-agonist. At the follow-up visit, 92.2% of patients reported that they felt better on Montelukast.
  
  
  CONCLUSIONS
  Leukotriene modifier Montelukast has significant additive benefits in the management of patients who suffer from mild-to-moderate asthma and who are inadequately controlled on inhaled corticosteroids therapy with or without long-acting bronchodilator.
authors.affiliation: Riyadh Military Hospital, Riyadh, Saudi Arabia. majidrees@gmail.com
authors.forename: Majdy M
authors.initials: MM
authors.lastname: Idrees
authors.forename: Mohamed S
authors.initials: MS
authors.lastname: Al Moamary