title: Seroprevalence of canine leishmaniasis and American trypanosomiasis in dogs from Grenada, West Indies.
abstract: Canine leishmaniasis and American trypanosomiasis (AT) are caused by related hemoflagellated parasites, Leishmania spp. and Trypanosoma cruzi, which share several common host species. Dogs are reservoirs for human infections by both pathogens. We determined the prevalence of antibodies to Leishmania spp. and T. cruzi in dogs from Grenada, West Indies. We examined 70 dog sera using the qualitative immunochromatographic dipstick tests (ICTs) based on recombinant antigens specific for visceral leishmaniasis and AT. Antibodies to visceral Leishmania were not detected in Grenadian dogs by ICT. Using the canine dipsticks for AT, antibodies to T. cruzi were determined in 3 (4.3%) of the 70 dogs. Results from this study indicate that dogs in Grenada are exposed in low levels to T. cruzi , but not to visceral Leishmania spp. at all.
authors.affiliation: Department of Natural Sciences and Mathematics, College of Science, Technology, Engineering and Mathematics, Johnson C. Smith University, 100 Beatties Ford Road, Charlotte, North Carolina 28216, USA. acrosypal@jcsu.edu
authors.forename: Alexa C
authors.initials: AC
authors.lastname: Rosypal
authors.forename: Shanesha
authors.initials: S
authors.lastname: Tripp
authors.forename: Christopher
authors.initials: C
authors.lastname: Kinlaw
authors.forename: R N
authors.initials: RN
authors.lastname: Sharma
authors.forename: D
authors.initials: D
authors.lastname: Stone
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D014355:Chagas Disease / Q000453:epidemiology / Q000662:veterinary*; D004197:Disease Reservoirs; D004283:Dog Diseases / Q000453:epidemiology* / Q000469:parasitology; D004285:Dogs; D019425:Grenada / Q000453:epidemiology; D007891:Leishmania / Q000276:immunology; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology / Q000662:veterinary*; D016036:Seroepidemiologic Studies; D012698:Serologic Tests / Q000379:methods / Q000662:veterinary; D014349:Trypanosoma cruzi / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan