title: Alternative mechanisms for tn5 transposition.
abstract: Bacterial transposons are known to move to new genomic sites using either a replicative or a conservative mechanism. The behavior of transposon Tn5 is anomalous. In vitro studies indicate that it uses a conservative mechanism while in vivo results point to a replicative mechanism. To explain this anomaly, a model is presented in which the two mechanisms are not independent--as widely believed--but could represent alternate outcomes of a common transpositional pathway.
authors.affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada. asada@ualberta.ca
authors.forename: Asad
authors.initials: A
authors.lastname: Ahmed
mesh_terms: D001419:Bacteria / Q000235:genetics*; D004251:DNA Transposable Elements; D008957:Models, Genetic
chemical_list: D004251:DNA Transposable Elements