title: Exogenous leptin administration decreases sperm count and increases the fraction of abnormal sperm in adult rats.
abstract: Daily intraperitoneal injection of 5-30 microg/kg body weight of leptin for 42 days to adult rats decreases sperm count and increases the fraction of abnormal sperm.
authors.affiliation: Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
authors.forename: Mohd Nizam
authors.initials: MN
authors.lastname: Haron
authors.forename: Urban J A
authors.initials: UJ
authors.lastname: D'Souza
authors.forename: Hasnan
authors.initials: H
authors.lastname: Jaafar
authors.forename: Rahimah
authors.initials: R
authors.lastname: Zakaria
authors.forename: Harbindar Jeet
authors.initials: HJ
authors.lastname: Singh
mesh_terms: D000818:Animals; D007274:Injections, Intraperitoneal; D020738:Leptin / Q000008:administration & dosage*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D011994:Recombinant Proteins / Q000008:administration & dosage; D012671:Seminiferous Tubules / Q000187:drug effects / Q000473:pathology; D013076:Sperm Count; D013094:Spermatozoa / Q000187:drug effects* / Q000473:pathology; D013997:Time Factors
chemical_list: D020738:Leptin; D011994:Recombinant Proteins