title: Difference between fasting and nonfasting triglyceridemia; the influence of waist circumference.
abstract: OBJECTIVE
  Postprandial hypertriglyceridemia is recognized as an independent risk factor for cardiovascular disease. The aim of this study was to identify differences between fasting and postprandial TG levels, focusing on the influence of waist circumference.
  
  
  METHODS
  Subjects included 1,505 men and 798 women aged 3865 years who were not taking medications for diabetes or dyslipidemia. Fasting TG levels were measured after an overnight fast, and postprandial TG levels were measured 2 hours after a standardized rice-based lunch (total 740 kcal, 20 g fat, 30 g protein, and 110 g carbohydrates) in the afternoon on the same day.
  
  
  RESULTS
  Fasting and postprandial TG levels were highly correlated in both men (r=0.86, p<0.001) and women (r=0.84, p<0.001). Waist circumference was positively correlated with fasting TG (r=0.38 in men and r=0.36 in women) and postprandial TG (r=0.42 in men and r=0.45 in women), respectively. On multiple regression analyses, the association of waist circumference with postprandial TG was still significant (standardized beta=0.10 in men and standardized beta=0.15 in women, p<0.001) after the inclusion of HbA1c, age, high-density-lipoprotein (HDL)-cholesterol, alcohol consumption, and fasting TG in the regression model.
  
  
  CONCLUSIONS
  Postprandial TG has a better relation with waist circumference than fasting TG.
authors.affiliation: Department of Internal Medicine, Hokuriku Central Hospital, Japan. ririoka@goo.jp
authors.forename: Rie
authors.initials: R
authors.lastname: Oka
authors.forename: Junji
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Miura
authors.forename: Shinya
authors.initials: S
authors.lastname: Nagasawa
authors.forename: Tadashi
authors.initials: T
authors.lastname: Moriuchi
authors.forename: Senshu
authors.initials: S
authors.lastname: Hifumi
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyamoto
authors.forename: Masa-Aki
authors.initials: MA
authors.lastname: Kawashiri
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nohara
authors.forename: Akihiro
authors.initials: A
authors.lastname: Inazu
authors.forename: Yoshiyu
authors.initials: Y
authors.lastname: Takeda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mabuchi
authors.forename: Kunimasa
authors.initials: K
authors.lastname: Yagi
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamagishi
mesh_terms: D000328:Adult; D000368:Aged; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference
chemical_list: D014280:Triglycerides