title: Profound teratospermia does not influence sex chromosomal aneuploidy rate in in vitro fertilization-preimplantation genetic diagnosis cycles.
abstract: Because spermatocyte meiotic error results in embryonic sex chromosomal aneuploidy, it is speculated that teratospermia correlates with increased embryonic sex chromosomal abnormalities. Our findings contradict this theory, suggesting that morphology does not correlate with sex chromosomal genotype.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Fertility and IVF, Washington, DC, USA. Mdayal@mfa.gwu.edu
authors.forename: Molina B
authors.initials: MB
authors.lastname: Dayal
authors.forename: Paul R
authors.initials: PR
authors.lastname: Gindoff
authors.forename: Shvetha
authors.initials: S
authors.lastname: Zarek
authors.forename: Douglas
authors.initials: D
authors.lastname: Peak
authors.forename: Anil
authors.initials: A
authors.lastname: Dubey
authors.forename: David
authors.initials: D
authors.lastname: Frankfurter
mesh_terms: D000293:Adolescent; D000328:Adult; D000782:Aneuploidy; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D005640:Follicle Stimulating Hormone / Q000097:blood; D005838:Genotype; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use; D008297:Male; D008423:Maternal Age; D054315:Oocyte Retrieval / Q000379:methods; D010062:Ovulation Induction / Q000379:methods; D010331:Paternal Age; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000379:methods*; D012729:Sex Chromosome Aberrations / Q000706:statistics & numerical data*; D013094:Spermatozoa / Q000002:abnormalities*; D017211:Treatment Failure
chemical_list: D006063:Chorionic Gonadotropin; D005300:Fertility Agents, Female; D004958:Estradiol; D005640:Follicle Stimulating Hormone; D016729:Leuprolide