title: A locally acquired falciparum malaria via nosocomial transmission in Korea.
abstract: A 57-year old man who was admitted to an emergency room of a tertiary hospital with hemoptysis developed malarial fever 19 days later and then died from severe falciparum malaria 2 days later. He had not traveled outside of Korea for over 30 years. Through intensive interviews and epidemiological surveys, we found that a foreign patient with a recent history of travel to Africa was transferred to the same hospital with severe falciparum malaria. We confirmed through molecular genotyping of the MSP-1 gene that Plasmodium falciparum genotypes of the 2 patients were identical. It is suggested that a breach of standard infection control precautions resulted in this P. falciparum transmission between 2 patients in a hospital environment. This is the first report of a nosocomial transmission of falciparum malaria in Korea.
authors.affiliation: Division of Malaria and Parasitic Disease, Korea Centers for Disease Control and Prevention (KCDC), Seoul, Korea.
authors.forename: Jung-Yeon
authors.initials: JY
authors.lastname: Kim
authors.forename: Jeong-Su
authors.initials: JS
authors.lastname: Kim
authors.forename: Mi-Hyun
authors.initials: MH
authors.lastname: Park
authors.forename: Young-A
authors.initials: YA
authors.lastname: Kang
authors.forename: Jun-Wook
authors.initials: JW
authors.lastname: Kwon
authors.forename: Shin-Hyeong
authors.initials: SH
authors.lastname: Cho
authors.forename: Byeong-Chul
authors.initials: BC
authors.lastname: Lee
authors.forename: Tong-Soo
authors.initials: TS
authors.lastname: Kim
authors.forename: Jong-Koo
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000349:Africa; D000595:Amino Acid Sequence; D000818:Animals; D003428:Cross Infection / Q000469:parasitology / Q000635:transmission*; D017809:Fatal Outcome; D006801:Humans; D007723:Korea; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission*; D008297:Male; D020066:Merozoite Surface Protein 1 / Q000737:chemistry / Q000235:genetics; D008875:Middle Aged; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification*; D015800:Protozoan Proteins / Q000737:chemistry / Q000235:genetics; D016415:Sequence Alignment; D014195:Travel
chemical_list: D020066:Merozoite Surface Protein 1; D015800:Protozoan Proteins