A convenient ultrasound-promoted regioselective synthesis of fused polycyclic 4-aryl-3-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridines.
Fused polycyclic 4-aryl-3-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridines were obtained in a three-component regioselective reaction of 5-amino-3-methyl-1H-pyrazole, 2H-indene-1,3-dione and arylaldehydes in ethanol under ultrasound irradiation. This rapid method produced the products in short reaction times (4-5min) and excellent yields (88-97%).
Nikpassand
Mohammad
M
Department of Chemistry, Faculty of Sciences, University of Guilan, Rasht, Iran.
Mamaghani
Manouchehr
M
Shirini
Farhad
F
Tabatabaeian
Khalil
K
D002625:Chemistry, Organic / Q000379:methods; D002626:Chemistry, Pharmaceutical / Q000379:methods; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D014465:Ultrasonics
C478081:1H-pyrazolo(3,4-b)pyridine; D011720:Pyrazoles; D011725:Pyridines