title: [Distribution of potentially hairpin-loop structures in the genome of bovine retroviruses].
abstract: Inverted repeats which can form hairpin-loop structures in the genomic RNA and cruciform structures in the proviral DNA of bovine leukemia virus (BLV) and bovine immunodeficiency virus (BIV) have been determined. Localization diagrams have been made up for hairpins (one of the elements of signaling genome function). The retroviruses BLV and BIV, about 8.5 kbp in length, are characterized by the varying quantitative and qualitative composition of hairpin-loop structures. The BLV and BIV genomes have been found to have 7 and 18 hairpins with energy (-deltaG) of more than 10 kcal/mol, respectively. Furthermore, in the BIV genome, there are 3 thermodynamically stable (i.e. detectable on model systems in vitro) hairpins (with the loop up to 6 nucleotides), two of them are perfect. But thermodynamically stable hairpins have not been found in the BLV genome.
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Limanskaia
authors.forename: A P
authors.initials: AP
authors.lastname: Limanskiĭ
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle; D004279:DNA, Viral / Q000737:chemistry* / Q000235:genetics; D016679:Genome, Viral / Q000235:genetics*; D016087:Immunodeficiency Virus, Bovine / Q000235:genetics*; D055029:Inverted Repeat Sequences / Q000235:genetics*; D001909:Leukemia Virus, Bovine / Q000235:genetics*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation
chemical_list: D004279:DNA, Viral