Paraneoplastic cerebellar degeneration mimicking acute post-infectious cerebellitis.
Acute cerebellitis is a monophasic non-progressive encephalitis restricted to the cerebellum, while paraneoplastic cerebellar degeneration is a subacute progressive disorder, which may either accompany or herald Hodgkin's disease. In the present report, we describe a young man with clinical and laboratory features of acute post-infectious cerebellitis in whom the progressive relapsing course subsequently led to the diagnosis of Hodgkin's disease. Dynamic changes observed on repeated MRIs during the protracted clinical course imply the presence of early active inflammation and subsequent neuronal atrophy.
Karmon
Yuval
Y
Department of Neurology, Meir General Hospital, Kfar Saba, Israel
Inbar
Edna
E
Cordoba
Mario
M
Gadoth
Natan
N
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000378:metabolism; D002531:Cerebellum / Q000473:pathology* / Q000503:physiopathology / Q000821:virology; D004660:Encephalitis / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D020362:Paraneoplastic Cerebellar Degeneration / Q000175:diagnosis*
D019268:Antibodies, Antineutrophil Cytoplasmic; D017730:Ki-1 Antigen