title: [Correlation between left ventricular stroke work loss index and aortic valve area in patients with aortic stenosis].
abstract: In echocardiographic evaluation of patients with aortic stenosis (AS), prospective studies have demonstrated that left ventricular stoke work loss index (LVSWLI) provide a more clinical efficacy than calculate of aortic valve area (AVA) by continuity equation to estimate severity of stenosis. The aim of this study was assess in our population of patients with AS the correlation between LVSWLI and AVA in regard to severity.
  
  
  METHODS
  Forty nine patients with moderate and severe AS were evaluated by transthoracic echocardiography. Grades of AS were assessed by transaortic flow velocity (Vmax) and mean aortic transvalvular gradient (deltaP). AVA and LVSWLI were calculated and Pearson's and Spearman's correlation coefficients between both methods were assessed. Significance level was set at <0.05.
  
  
  RESULTS
  The age of the patients was 66 +/- 13 (31-84 years). Thirty four (69%) patients had severe AS and 15 (31%) moderate AS. The Pearson's correlation coefficient between LVSWLI and AVA was 0.79 (p<0.04) and between LVSWLI and deltaP was 0.90 (p<0.03). The Spearman's correlation coefficient between LVSWLI and symptomatic status was 0.70 (rho = 0.70, p < 0.003).
  
  
  CONCLUSIONS
  In patients with moderate and severe AS, the correlation between LVSWLI and deltaP is higher than correlation between LVSWLI and AVA. Moreover LVSWLI has a higher correlation with presence of symptoms than AVA.
authors.affiliation: Servicio de Medicina Interna, Hospital General "Dr. Gaudencio González Garza", Centro Médico Nacional "La Raza", Instituto Mexicano del Seguro Social (IMSS), México, D.F. México. gustavodiazarrieta@yahoo.com
authors.forename: Gustavo
authors.initials: G
authors.lastname: Díaz-Arrieta
authors.forename: Noé Fernando
authors.initials: NF
authors.lastname: Zamorano-Velázquez
authors.forename: José Gustavo
authors.initials: JG
authors.lastname: Hernández-Martínez
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez-Hernández
authors.forename: Jorge Guillermo
authors.initials: JG
authors.lastname: Arenas-Fonseca
authors.forename: Alicia Haydeé
authors.initials: AH
authors.lastname: Mendoza-Carmona
authors.forename: Margarita
authors.initials: M
authors.lastname: Téllez-Bautista
authors.forename: Alicia
authors.initials: A
authors.lastname: Contreras-Rodríguez
authors.forename: Francisco
authors.initials: F
authors.lastname: Martínez-Baca-López
authors.forename: Beda
authors.initials: B
authors.lastname: Espinosa-Caleti
authors.forename: María Elsa
authors.initials: ME
authors.lastname: Mendoza-Hernández
authors.forename: Luis David
authors.initials: LD
authors.lastname: Sánchez-Velázquez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000473:pathology*; D001024:Aortic Valve Stenosis / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D013318:Stroke Volume