X-ray reflectivity study on the structure and phase stability of mixed phospholipid multilayers.
Vertically oriented multilayers composed of two saturated phospholipids, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphoserine (DPPS), were deposited on silicon. X-ray reflectivity was used to investigate the structures of the variously mixed phospholipid multilayers as a function of composition. Then, the phase stability was investigated at various annealing temperatures under humid conditions. The results indicated that the lipid spacing of the mixed phospholipid multilayers varied systematically as a function of the DPPC/DPPS ratio and that no macroscopic phase separation occurred during the annealing process under both dry and humid conditions.
Jing
H Y
HY
Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang-HANARO Joint Center for Biological Interfaces, Sogang University, Seoul 121-742, Korea.
Hong
D H
DH
Kwak
B D
BD
Choi
D J
DJ
Shin
K
K
Yu
C J
CJ
Kim
J W
JW
Noh
D Y
DY
Seo
Y S
YS
D004583:Electrons; D010743:Phospholipids / Q000737:chemistry*; D014961:X-Ray Diffraction
D010743:Phospholipids