title: Development of two certified reference materials for acrylamide determination in foods.
abstract: Certified reference materials (CRMs) are a versatile tool for quality assurance in the chemical laboratory. In the case of acrylamide analysis, the availability of appropriate materials was rather limited. This lack of acrylamide matrix CRMs has now been overcome by the development of two European reference materials (ERM) for the determination of acrylamide in food (crispbread, ERM-BD272, and rusk, ERM-BD274). This article describes the preparation of the materials, provides the results of the homogeneity and stability studies, and presents and discusses the outcome of the certification studies. Expert laboratories from different European countries took part in the certification studies using various analytical methods. The acrylamide mass fractions were certified to 980 microg kg(-1) for crispbread and 74 microg kg(-1) for rusk.
authors.affiliation: BAM Federal Institute for Materials Research and Testing, Richard-Willstaetter-Strasse 11, D-12489 Berlin, Germany. matthias.koch@bam.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Koch
authors.forename: Wolfram
authors.initials: W
authors.lastname: Bremser
authors.forename: Robert
authors.initials: R
authors.lastname: Koeppen
authors.forename: David
authors.initials: D
authors.lastname: Siegel
authors.forename: Antje
authors.initials: A
authors.lastname: Toepfer
authors.forename: Irene
authors.initials: I
authors.lastname: Nehls
mesh_terms: D020106:Acrylamide / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D005060:Europe; D005504:Food Analysis / Q000592:standards*; D008401:Gas Chromatography-Mass Spectrometry; D007753:Laboratories / Q000592:standards; D011786:Quality Control; D012015:Reference Standards; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D020106:Acrylamide