SAD kinase keeps centrosomes lonely.
Centrosome duplication is under strict control such that it occurs only once per cell cycle. New insights into the molecular mechanisms that control centrosome number come from the discovery of a role for SADB kinase in centrosome biogenesis.
Chen
Daici
D
Vogel
Jackie
J
D000818:Animals; D018385:Centrosome / Q000201:enzymology*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008954:Models, Biological; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014404:Tubulin / Q000737:chemistry / Q000378:metabolism
D047908:Intracellular Signaling Peptides and Proteins; D014404:Tubulin; D010768:Phosphoserine; C523084:BRSK1 protein, human; C496826:Brsk1 protein, mouse; D017346:Protein Serine-Threonine Kinases