title: Chemical composition and antimicrobial activity of the essential oils of Lavandula stoechas L. ssp. stoechas growing wild in Turkey.
abstract: The chemical compositions of the essential oils obtained by hydrodistillation from the dried leaves and flowers of Lavandula stoechas L. ssp. stoechas were separately identified by GC-FID and GC-MS analyses. The main components were alpha-fenchone (41.9 +/- 1.2%), 1,8-cineole (15.6 +/- 0.8%), camphor (12.1 +/- 0.5%), and viridiflorol (4.1 +/- 0.4%) in the leaves; and alpha-fenchone (39.2 +/- 0.9%), myrtenyl acetate (9.5 +/- 0.4%), alpha-pinene (6.1 +/- 0.09%), camphor (5.9 +/- 0.05%) and 1,8-cineole (3.8 +/- 0.1%) in the flowers. Overall, 55 and 66 constituents were identified in the leaf and flower essential oils representing more than 90% and 94% of the total, respectively. In addition, the essential oils were evaluated for their antibacterial and anticandidal activities by broth microdilution. The flower essential oil was found to be relatively more active than the leaf oil towards the tested pathogenic microorganisms. Methicillin-resistant Staphylococcus aureus was more susceptible to the flower oil (MIC = 31.2 microg/mL). The oils, evaluated for their free radical scavenging activity using a TLC-DPPH assay, were inactive at a concentration of 2 mg/mL.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Yeditepe University, TR-34755, Kayişdaği, Istanbul, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Kirmizibekmez
authors.forename: Betül
authors.initials: B
authors.lastname: Demirci
authors.forename: Erdem
authors.initials: E
authors.lastname: Yeşilada
authors.forename: K Hüsnü Can
authors.initials: KH
authors.lastname: Başer
authors.forename: Fatih
authors.initials: F
authors.lastname: Demirci
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002175:Candida / Q000187:drug effects; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D027523:Lavandula / Q000737:chemistry*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009822:Oils, Volatile