Palladium-catalyzed direct arylation of electron-deficient polyfluoroarenes with arylboronic acids.
The palladium-catalyzed direct arylation of electron-deficient arenes that contain two or more fluorine groups with arylboronic acids was realized. The key to achieving a broad substrate scope with respect to both polyfluorobenzenes and arylboronic acids is the choice of bases depending on acidities of polyfluorobenzenes.
Wei
Ye
Y
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Kan
Jian
J
Wang
Min
M
Su
Weiping
W
Hong
Maochun
M