Imagining the possibilities: ripples, routes, and reactivation.
Hippocampal place cells fire selectively when a rat occupies a particular location. Under certain conditions, the cells briefly represent trajectories along locations away from the rat's current location. New results lend important insight into this phenomenon and demonstrate spatiotemporally coherent, cognitive representations that are independent of current sensory input.
Knierim
James J
JJ
Zanvyl Krieger Mind/Brain Institute and Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21218, USA. jknierim@jhu.edu
D000818:Animals; D003071:Cognition / Q000502:physiology*; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D006801:Humans; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D051381:Rats; D013037:Spatial Behavior / Q000502:physiology*