Comparison of interval breast cancer rates for two-versus single-view screening mammography: a population-based study.
OBJECTIVE
To determine whether the implementation of two-view mammography was followed by a reduction in the rates of interval cancers.


METHODS
We analyzed the data concerning women aged 50-69 who attended the breast cancer screening program between January 1, 1994 and December 31, 2006 in Isère, France. We performed Poisson regressions to estimate age-adjusted rate ratios of women being recalled, cancer detection, and interval cancer for two-view compared to single-view mammography.


RESULTS
After adjusting for age, two-view mammography was associated with a higher risk of cancer detection (1.37 [95% CI, 1.16-1.62]) and with a decreased risk of 12-month (0.46 [95% CI, 0.23-0.92]) and 24-month (0.64 [95% CI, 0.46-0.88]) interval cancer.


CONCLUSIONS
Two-view mammography for first and subsequent screens is associated with lower rates of interval breast cancer. This is at the expense of an increased number of women being recalled for further assessment after subsequent screens.
Seigneurin
A
A
Registre du Cancer de l'Isère, 23 Chemin des Sources, Meylan, France. aseigneurin@chu-grenoble.fr
Exbrayat
C
C
Labarère
J
J
Colonna
M
M
D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000517:prevention & control*; D003951:Diagnostic Errors; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008327:Mammography / Q000379:methods* / Q000592:standards; D008403:Mass Screening / Q000592:standards*; D008875:Middle Aged; D016012:Poisson Distribution