Citrobacter koseri meningitis: a neurosurgical condition?
A 2-month-old girl developed meningitis, ventriculitis and brain abscess in the course of Citrobacter koseri infection. She was successfully treated with the combined use of antibiotics, intra-cavitary urokinase and surgery, thus avoiding the development of hydrocephalus and of ventricular loculation. C. koseri is a Gram-negative pathogen with a strong predilection for the neonatal brain. Brain abscesses develop in roughly 77% of cases, causing severe neurological sequels in one-half and death in one-third of patients. The authors aim to report the role of neurosurgical treatment for managing the severe complications that may arise in the course of C. koseri brain infection and the use of urokinase for preventing the development of loculated hydrocephalus.
Martínez-Lage
Juan F
JF
Regional Service of Neurosurgery, Virgen de la Arrixaca University Hospital, 30120 El Palmar, Murcia, Spain. juanf.martinezlage@cablemurcia.com
Martínez-Lage Azorín
Laura
L
Almagro
María José
MJ
Bastida
María Encarnación
ME
Reyes
Susana
S
Tellez
Cinthia
C
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D041041:Citrobacter koseri / Q000472:pathogenicity*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant
D000900:Anti-Bacterial Agents