title: A proposal of combined evaluation of waist circumference and BMI for the diagnosis of metabolic syndrome.
abstract: We performed a receiver operator characteristic (ROC) curve analysis of 3915 men and 2032 women. Subjects who were diagnosed with two or more factors among high blood pressure, hyperglycaemia or high triglyceride and/or low HDL were classified as the metabolic syndrome group. By performing a ROC curve analysis, we have determined the cut-off point of waist circumference (WC) and BMI to define metabolic syndrome and further calculated the sensitivity and specificity of these two factors for the diagnosis. Cut-off point for the diagnosis of metabolic syndrome was 85 cm (men) and 80 cm (women) in WC and 24 (men) and 23 (women) in BMI. By combining these two factors, the sensitivity for the diagnosis increased to more than 80%. We conclude that it is beneficial to combine both WC and BMI for diagnosis of metabolic syndrome.
authors.affiliation: Diabetes and Metabolic Disease Research Centre, Hidaka Hospital, Gunma, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Takahashi
authors.forename: Kenju
authors.initials: K
authors.lastname: Shimomura
authors.forename: Peter
authors.initials: P
authors.lastname: Proks
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Craig
authors.forename: Mayumi
authors.initials: M
authors.lastname: Negishi
authors.forename: Masako
authors.initials: M
authors.lastname: Akuzawa
authors.forename: Rikuro
authors.initials: R
authors.lastname: Hayashi
authors.forename: Yohnosuke
authors.initials: Y
authors.lastname: Shimomura
authors.forename: Isao
authors.initials: I
authors.lastname: Kobayashi
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003940:Diagnostic Techniques, Endocrine; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis*; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012372:ROC Curve; D012016:Reference Values; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012727:Sex Characteristics; D055105:Waist Circumference