Psychopathology among preterm infants using the Diagnostic Classification Zero to Three.
OBJECTIVE
To compare the prevalence of psychopathology in infants born preterm with matched full-term infants at the corrected age of 1 year.


METHODS
Between June 2003 and April 2005, a case-control longitudinal cohort study was conducted at the neonatal unit of the University Hospital of Antwerp, Belgium. We prospectively enrolled 123 live-born infants between 25 and 35 weeks of gestation and/or infants with a birth-weight of <1500 g. Thirty full-term infants were recruited among day care centres in the region. Diagnoses were based on the Diagnostic Classification Zero to Three (DC: 0-3), using the MacArthur Communicative Developmental Inventory Dutch version, Infant-Toddler Sensory Profile, Bayley Scales of Infant Development II, Parent Infant Relationship Global Assessment Scale and Functional Emotional Assessment Scale.


RESULTS
At the (corrected) age of 12 months, 89 infants were eligible for follow-up and complete data were available for 69 (77%) infants. Fifty-four percentage of the preterm infants fulfilled one or more DC 0-3 diagnoses. Premature infants had significantly more diagnoses than full-term infants on axis I, axis III and axis V of the DC: 0-3.


CONCLUSIONS
In this study, the prevalence of psychopathology was significantly higher among preterm infants in comparison with full-term infants. This study did not confirm previous findings of higher rates of relationship disorders among preterm infants.
Janssens
A
A
Collaborative Antwerp Psychiatric Research Institute, University of Antwerp, Antwerp, Belgium. astrid.janssens@ua.ac.be
Uvin
K
K
Van Impe
H
H
Laroche
S M F
SM
Van Reempts
P
P
Deboutte
D
D
D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000453:epidemiology*; D019102:Infant, Very Low Birth Weight; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D015997:Neonatal Screening / Q000379:methods*; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D047929:Term Birth