Protein conjugates of SH3-domain ligands and ATP-competitive inhibitors as bivalent inhibitors of protein kinases.
Tiwari
Rakesh
R
Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, 41 Lower College Road, Kingston, RI 02881, USA.
Parang
Keykavous
K
D000255:Adenosine Triphosphate / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000595:Amino Acid Sequence; D001667:Binding, Competitive; D006147:Guanine / Q000031:analogs & derivatives / Q000737:chemistry; D006801:Humans; D008024:Ligands; D019853:O(6)-Methylguanine-DNA Methyltransferase / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D018909:src Homology Domains
D008024:Ligands; D047428:Protein Kinase Inhibitors; C064976:O(6)-benzylguanine; D006147:Guanine; D000255:Adenosine Triphosphate; D019853:O(6)-Methylguanine-DNA Methyltransferase