Skeletal muscle sings a choral stem cell lullaby.
Constraint of stem cell number in skeletal muscle is investigated by Abou-Khalil et al. (2009), in this issue of Cell Stem Cell. Their results attribute it both to autocrine positive feedback and to paracrine signals from the surrounding cellular community.
Duguez
Stephanie
S
Center for Genetic Medicine, Children's National Medical Center, Washington, D.C. 20010, USA.
Partridge
Terry
T
D042683:Angiopoietin-1 / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D019898:Autocrine Communication / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D051379:Mice; D019899:Paracrine Communication / Q000187:drug effects; D042787:Receptor, TIE-2 / Q000378:metabolism; D032496:Satellite Cells, Skeletal Muscle / Q000166:cytology* / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D013234:Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism
D042683:Angiopoietin-1; D042787:Receptor, TIE-2