title: Dynamic behavior of giant liposomes at desired osmotic pressures.
abstract: To apply accurate and uniform osmotic pressures to liposomes, they can be formed using the spontaneous transfer method in solutions with different osmolarities. The majority of liposomes unexpectedly opened large holes (several micrometers in diameter) in response to the osmotic pressure regardless of its strength, that is, the difference between the outside and inside solute (sucrose or KCl) concentrations. However, the lag time for any response, including the opening of a hole, after the formation of the liposome decreased with increasing osmotic pressure.
authors.affiliation: Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
authors.forename: Masae
authors.initials: M
authors.lastname: Ohno
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hamada
authors.forename: Kingo
authors.initials: K
authors.lastname: Takiguchi
authors.forename: Michio
authors.initials: M
authors.lastname: Homma
mesh_terms: D008081:Liposomes / Q000737:chemistry*; D009997:Osmotic Pressure; D011189:Potassium Chloride / Q000737:chemistry; D012996:Solutions; D013395:Sucrose / Q000737:chemistry; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D008081:Liposomes; D012996:Solutions; D014867:Water; D013395:Sucrose; D011189:Potassium Chloride