Cis-regulatory elements in plant cell signaling.
Plant cell signaling pathways are in part dependent on transcriptional regulatory networks comprising circuits of transcription factors (TFs) and regulatory DNA elements that control the expression of target genes. Here, we describe experimental and bioinformatic approaches for identifying potential cis-regulatory elements. We also discuss recent integrative genomics studies aimed at elucidating the functions of cis-regulatory elements in aspects of plant biology, including the circadian clock, interactions with the environment, stress responses, and regulation of growth and development by phytohormones. Finally, we discuss emerging technologies and approaches that offer great potential for accelerating the discovery and functional characterization of cis-elements and interacting TFs--which will help realize the promise of systems biology.
Priest
Henry D
HD
Department of Botany and Plant Pathology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331, USA.
Filichkin
Sergei A
SA
Mockler
Todd C
TC
D001683:Biological Clocks; D002940:Circadian Rhythm; D019295:Computational Biology; D018744:DNA, Plant / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D010937:Plant Growth Regulators / Q000378:metabolism; D010944:Plants / Q000235:genetics* / Q000378:metabolism; D050436:Regulatory Elements, Transcriptional; D015398:Signal Transduction; D013312:Stress, Physiological
D018744:DNA, Plant; D010937:Plant Growth Regulators