May sarcoidal reaction and malignant features coexist in regional lymph nodes of non-small cell lung cancer patients?
In the study of Steinfort et al., as well as in previous studies, no cases of co-involvement of malignant features and sarcoidal reactions were seen in non-small cell lung cancer patients undergoing mediastinal staging, leading the authors to state that non-necrotizing granulomas revealed by EBUS-TBNA should serve to indicate the absence of lymph node metastases. We report on a case of stage IIIA pulmonary adenocarcinoma in which TBNA of a subcarinal node showed the presence of both neoplastic cells and non-necrotizing granulomas.
Trisolini
Rocco
R
Cancellieri
Alessandra
A
Patelli
Marco
M
D001707:Biopsy, Needle / Q000379:methods; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology*