title: Segmental mediolytic arteriopathy with post-transplant lymphoproliferative disorder of the lung: case report and review of the literature.
abstract: Segmental mediolytic arteriopathy (SMA) is an extremely rare condition of uncertain etiology causing degeneration of arterial media, intramural dissection or the rupture of aneurysms. It is recognized as a rare cause of fatal intra-abdominal bleeding. We report the first case of recurrent intra-abdominal bleeding secondary to SMA in a lung transplant patient, with a further complication of lymphoproliferative disease in the transplanted lung. We discuss the pathogenesis, clinical presentation, imaging characteristics and the complexities of management in this case.
authors.affiliation: Department of Transplant, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK. n_u_khan@hotmail.com
authors.forename: Nouman U
authors.initials: NU
authors.lastname: Khan
authors.forename: Ursalan
authors.initials: U
authors.lastname: Khan
authors.forename: Mohamed
authors.initials: M
authors.lastname: Al-Aloul
authors.forename: Nizar
authors.initials: N
authors.lastname: Yonan
authors.forename: Noman
authors.initials: N
authors.lastname: Khasati
authors.forename: Ali
authors.initials: A
authors.lastname: Machaal
authors.forename: Helen
authors.initials: H
authors.lastname: Doran
authors.forename: Colm
authors.initials: C
authors.lastname: Leonard
mesh_terms: D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D004646:Emphysema / Q000209:etiology / Q000601:surgery*; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects / Q000379:methods*; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D014019:Tissue Donors / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications / Q000601:surgery*