[Relationship between body mass index and colon cancer].
OBJECTIVE
Obesity is associated with increased risk of colorectal cancer. Many studies showed that body mass index (BMI) is related to the incidence of colon cancer. This study was to explore the relationship between BMI and colon cancer in Chinese population and provide evidences for the prevention of colon cancer.


METHODS
Clinical data, including BMI, of 707 colon cancer patients and 709 healthy subjects were compared.


RESULTS
The mean BMI was significantly higher in colon cancer patients than in healthy subjects [(24.52+/-4.56) kg/m2 vs. (23.75+/-3.14) kg/m2, t=-3.72, P<0.001]. When stratified by sex and age, the BMI was always higher in colon cancer patients than in healthy subjects. Logistic regression analyses showed that BMI was an important risk factor of colon cancer (odds ratio=1.059, 95% confidence interval=1.029-1.090).


CONCLUSIONS
The occurrence of colon cancer in Chinese population is related to BMI.
Zheng
Mei-Chun
MC
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, PR China.
Kong
Ling-Heng
LH
Lu
Zhen-Hai
ZH
Fang
Yu-Jing
YJ
Pan
Zhi-Zhong
ZZ
Zhu
Ya-Ping
YP
Wen
Yong-Shan
YS
Wan
De-Sen
DS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002681:China / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D016017:Odds Ratio; D012307:Risk Factors; D055815:Young Adult