Spondyloarthritis, diffuse idiopathic skeletal hyperostosis (DISH) and chondrocalcinosis.
The authors describe the main clinical and radiological findings of common enthesopathic disorders-spondylarthritis (SpA), chondrocalcinosis/calcium pyrophosphate dehydrate crystal deposition disease (CPPD CDD) and diffuse idiopathic skeletal hyperostosis (DISH), stressing similarities and differences which may help in the differential diagnosis. They emphasize the clinical presentation of the "pseudoankylosing spondylitis" forms of CPPD CDD. They also review the most relevant genes and molecular mechanisms associated with these conditions and with another enthesopathic disorder with high prevalence in the Japanese population-ossification of the posterior longitudinal ligament (OPLL).
Armas
Jácome Brugues
JB
SEEBMO, Hospital de Santo Espirito de Angra do Heroísmo, Azores, Portugal. jacome.armas@netc.pt
Couto
Ana Rita
AR
Bettencourt
Bruno Filipe
BF
D000818:Animals; D002114:Calcinosis; D002805:Chondrocalcinosis / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease; D006801:Humans; D004057:Hyperostosis, Diffuse Idiopathic Skeletal / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology; D017887:Ossification of Posterior Longitudinal Ligament / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D011859:Radiography; D025241:Spondylarthritis / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology