Surface-mediated DNA self-assembly.
This communication reports a strategy for solid surface-mediated DNA self-assembly. DNA molecules weakly interact with solid surfaces; thus are confined to solid surfaces. The confinement reduces the flexibility of DNA nanomotifs and promotes the DNA 2D crystals to grow on solid surfaces. As a demonstration, periodic DNA nanoarrays have been directly assembled onto mica surfaces. Such in situ assembly eliminates the sample transfer process between assembly and characterization and possible applications.
Sun
Xuping
X
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.
Hyeon Ko
Seung
S
Zhang
Chuan
C
Ribbe
Alexander E
AE
Mao
Chengde
C
D000538:Aluminum Silicates / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D020411:Oligonucleotide Array Sequence Analysis; D012996:Solutions; D013499:Surface Properties; D013696:Temperature
D000538:Aluminum Silicates; D012996:Solutions; D004247:DNA; C011934:mica