title: Prediction of the chromatographic signal in gradient elution ion chromatography.
abstract: This study describes the development of a signal prediction model in gradient elution ion chromatography. The proposed model is based on a retention model and generalized logistic peak shape function which guarantees simplicity of the model and its easy implementation in method development process. Extensive analysis of the model predictive ability has been performed for ion chromatographic determination of bromate, nitrite, bromide, iodide, and perchlorate, using KOH solutions as eluent. The developed model shows good predictive ability (average relative error of gradient predictions 1.94%). The developed model offers short calculation times as well as low experimental effort (only nine isocratic runs are used for modeling).
authors.affiliation: University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, Croatia. Tomislav.Bolanca@fkit.hr
authors.forename: Tomislav
authors.initials: T
authors.lastname: Bolanca
authors.forename: Stefica Cerjan
authors.initials: SC
authors.lastname: Stefanović
authors.forename: Sime
authors.initials: S
authors.lastname: Ukić
authors.forename: Marko
authors.initials: M
authors.lastname: Rogosić
authors.forename: Melita
authors.initials: M
authors.lastname: Lusa