Radiation techniques and toxicities for locally advanced breast cancer.
Radiation therapy is used in the management of locally advanced breast cancer in the postmastectomy or neoadjuvant chemotherapy and breast-conservation setting to improve local-regional control and survival. Using modern-day technology, the therapeutic ratio has increased and the potential morbidity has decreased. This article reviews the technical aspects of radiation therapy for locally advanced breast cancer with emphasis on 3-dimensional radiotherapy techniques and discusses potential toxicities and how to reduce them.
Moran
Meena S
MS
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520-8040, USA. meena.moran@yale.edu
Haffty
Bruce G
BG
D001365:Axilla; D020516:Brachial Plexus Neuropathies / Q000209:etiology; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006321:Heart / Q000528:radiation effects; D006801:Humans; D008168:Lung / Q000528:radiation effects; D008207:Lymphatic Metastasis; D008209:Lymphedema / Q000209:etiology; D011832:Radiation Injuries; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal; D050397:Radiotherapy, Intensity-Modulated