title: [Effect of Helicobacter pylori eradication on childhood acute idiopathic thrombocytopenic purpura].
abstract: OBJECTIVE
  To evaluate the effect of Helicobacter pylor (Hp) eradication in children with acute idiopathic thrombocytopenic purpura (ITP).
  
  
  METHODS
  Ninety-three children with acute ITP and Hp infection were divided into two groups and treated with prednisone and Hp eradication (group A, 51 cases) or with prednisone without Hp eradication (group B, 42 cases).
  
  
  RESULTS
  The Hp eradication rate was 94.1% in group A. No difference was found in the therapeutic effects on IPT between the two groups, but the recurrence rate in one year in group A was significantly lower than that in group B.
  
  
  CONCLUSIONS
  NHp eradication does not obviously enhance the therapeutic effect on childhood acute ITP, but can decrease the relapse rate in one year. HP eradication therapy is recommended in children with acute ITP and Hp infection.
authors.affiliation: Department of Pediatrics, Second Hospital of Yueyang City, Yueyang, China. lizhaoxia08@sina.com
authors.forename: Chao-Xia
authors.initials: CX
authors.lastname: Li
authors.forename: Di-Jun
authors.initials: DJ
authors.lastname: Liu
authors.forename: Chun-Qiu
authors.initials: CQ
authors.lastname: Pan
authors.forename: Xian-Fu
authors.initials: XF
authors.lastname: Sang
authors.forename: Xu
authors.initials: X
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects* / Q000276:immunology; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000276:immunology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D011241:Prednisone