Gastric bypass and glucose metabolism.
Roux-en-Y gastric bypass leads to a marked improvement of glucose control. The mechanisms are only partly known. Gastrointestinal hormones may play a role. Of these, glucagon-like peptide 1 and peptide YY have been most consistently associated with the beneficial effects of gastric bypass on glucose metabolism and weight. In this paper, a short review of the topic is presented and a suggestion of the improvement of glucose metabolism is made based on the current published work.
Ukkola
O
O
Department of Internal Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland. olavi.ukkola@oulu.fi
D000818:Animals; D015390:Gastric Bypass / Q000379:methods* / Q000639:trends; D005768:Gastrointestinal Hormones / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D038321:Glycemic Index / Q000502:physiology; D006801:Humans; D009765:Obesity / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery; D015431:Weight Loss / Q000502:physiology
D005768:Gastrointestinal Hormones; D005947:Glucose