title: Severe acute renal failure in a patient with diabetic ketoacidosis.
abstract: Acute renal failure (ARF) is a rare but potentially fatal complication of diabetic ketoacidosis (DKA). Early recognition and aggressive treatment of ARF during DKA may im-prove the prognosis of these patients. We present a case report of a 12 year old female admitted to the hospital with severe DKA as the 1s t manifestation of her diabetes mellitus. She presented with severe metabolic acidosis, hypophosphatemia, and oliguric ARF. In addition, rhabdomyolysis was noted during the course of DKA which probably contributed to the ARF. Management of DKA and renal replacement therapy resulted in quick recovery of renal function. We suggest that early initiation of renal replacement therapy for patients with DKA developing ARF may improve the potentially poor outcome of patients with ARF associated with DKA.
authors.affiliation: Department of Pediatrics, Division of Nephrology, Children's Hospital of Eastern Ontario, Ottawa, Canada.
authors.forename: Jamila
authors.initials: J
authors.lastname: Al-Matrafi
authors.forename: Jennifer
authors.initials: J
authors.lastname: Vethamuthu
authors.forename: Janusz
authors.initials: J
authors.lastname: Feber
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016883:Diabetic Ketoacidosis / Q000150:complications* / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D017674:Hypophosphatemia / Q000209:etiology; D009846:Oliguria / Q000209:etiology; D017582:Renal Replacement Therapy; D012206:Rhabdomyolysis / Q000209:etiology; D012720:Severity of Illness Index; D016896:Treatment Outcome