title: Copper nitrate catalyzed three-component one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones.
abstract: An efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones from aldehydes, 1,3-dicarbonyl compounds, and urea using copper nitrate under refluxing temperature in ethanol was described. Compared with other Lewis copper salts, copper nitrate proved to be the most efficient. The advantages of the new method were good yields (61-93%), short reaction time (0.4-3 h), and inexpensive catalyst.
authors.affiliation: College of Chemistry and Chemical Engineering, Bohai University, Jinzhou, Liaoning, P. R. China. minwangszg@yahoo.com.cn
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Heng
authors.initials: H
authors.lastname: Jiang
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Song
authors.forename: Hong
authors.initials: H
authors.lastname: Gong
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D009566:Nitrates / Q000737:chemistry*; D011744:Pyrimidinones / Q000138:chemical synthesis*; D014508:Urea / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D009566:Nitrates; D011744:Pyrimidinones; D003300:Copper; D014508:Urea