title: Idiopathic focal segmental glomerulosclerosis.
abstract: This study was conducted to determine the prognostic value of some clinical, laboratory, histopathologic and therapeutic factors in 62 children with focal segmental glomerulosclerosis. There were no significant differences between the factors studied, except for severe interstitial fibrosis, which was more frequent in patients with chronic kidney disease (P=0.03). The prevalence of chronic kidney disease in nonresponder groups was significantly higher (P <0.05). We found therapy with cyclophosphamide to be promising in patients with focal segmental glomerulosclerosis.
authors.affiliation: Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran. Naserim@mums.ac.ir
authors.forename: Mitra
authors.initials: M
authors.lastname: Naseri
authors.forename: Abbas
authors.initials: A
authors.lastname: Madani
authors.forename: Nematolah
authors.initials: N
authors.lastname: Attaii
authors.forename: Homa
authors.initials: H
authors.lastname: Naseri
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007492:Iran; D053208:Kaplan-Meier Estimate; D008297:Male; D009404:Nephrotic Syndrome; D015995:Prevalence; D018709:Statistics, Nonparametric; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013256:Steroids; D003520:Cyclophosphamide