title: Competing domino processes: path-discriminating ability of epoxide stereochemistry at the angular position.
abstract: Structurally different products can be reached selectively from unsaturated vicinal bicyclic diols, which differ only by the epoxide configuration at the angular position. It is possible to modify the regiochemical outcome of the domino process in such a way as to create a different pathway, [4 + 2] versus [4 + 3 + 2], and control product distribution by using the configuration bias. No previous example of a domino variant of the [4 + 3 + 2] process appears to have been documented.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS, F-91198 Gif-sur-Yvette, France.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Aquino
authors.forename: Imad
authors.initials: I
authors.lastname: Safir
authors.forename: Zobida
authors.initials: Z
authors.lastname: Elkhayat
authors.forename: Zoila
authors.initials: Z
authors.lastname: Gandara
authors.forename: Manuel
authors.initials: M
authors.lastname: Perez
authors.forename: Pascal
authors.initials: P
authors.lastname: Retailleau
authors.forename: Siméon
authors.initials: S
authors.lastname: Arseniyadis
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D004852:Epoxy Compounds / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D004852:Epoxy Compounds