title: Intravenous leiomyomatosis with intracardiac extension: a single-institution experience.
abstract: OBJECTIVE
  The aim of this study was to outline the surgical management and outcomes for patients diagnosed with intravenous leiomyomatosis with intracardiac extension at a single institution.
  
  
  METHODS
  This was a retrospective review of patients diagnosed with intravenous leiomyomatosis with intracardiac extension between 2002-2008.
  
  
  RESULTS
  Four patients were identified. The surgical approach in 3 (75%) patients was a single-stage operation. Four (100%) patients presented with cardiac symptoms: 3 (75%) with syncope and 1 (25%) with an abnormal electrocardiogram. Mean age at presentation was 48 years (range, 42-58 years). Complete resection of tumor was obtained in 1 (25%) patient and 3 (75%) patients experienced incomplete resection. Mean follow-up, including surveillance imaging, was 25.5 months (range, 8-57 months) and all 4 patients (100%) are currently free of recurrence.
  
  
  CONCLUSIONS
  Surgical excision remains an effective therapy for treating patients with benign metastasizing leiomyomatosis. Incomplete surgical resection may result in favorable response.
authors.affiliation: Department of Obstetrics and Gynecology, New York Presbyterian Hospital-Weill-Cornell Medical College, New York, NY, USA.
authors.forename: Micheal J
authors.initials: MJ
authors.lastname: Worley
authors.forename: Anate
authors.initials: A
authors.lastname: Aelion
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Caputo
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Kent
authors.forename: Arash
authors.initials: A
authors.lastname: Salemi
authors.forename: Karl H
authors.initials: KH
authors.lastname: Krieger
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Goldstein
authors.forename: Dennis Y
authors.initials: DY
authors.lastname: Kuo
authors.forename: Brian M
authors.initials: BM
authors.lastname: Slomovitz
mesh_terms: D000328:Adult; D005260:Female; D006338:Heart Neoplasms / Q000556:secondary / Q000601:surgery*; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery*