title: On the causes of outliers in Affymetrix GeneChip data.
abstract: We describe various types of outliers seen in Affymetrix GeneChip data. We have been able to utilise the data in the Gene Expression Omnibus to screen GeneChips across a range of scales, from single probes, to spatially adjacent fractions of arrays, to whole arrays, to whole experiments. In this review we describe a number of causes for why some reported intensities might be misleading on GeneChips.
authors.affiliation: University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK.
authors.forename: Graham J G
authors.initials: GJ
authors.lastname: Upton
authors.forename: Olivia
authors.initials: O
authors.lastname: Sanchez-Graillet
authors.forename: Joanna
authors.initials: J
authors.lastname: Rowsell
authors.forename: Jose M
authors.initials: JM
authors.lastname: Arteaga-Salas
authors.forename: Neil S
authors.initials: NS
authors.lastname: Graham
authors.forename: Maria A
authors.initials: MA
authors.lastname: Stalteri
authors.forename: Farhat N
authors.initials: FN
authors.lastname: Memon
authors.forename: Sean T
authors.initials: ST
authors.lastname: May
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Harrison
mesh_terms: D016477:Artifacts; D001483:Base Sequence; D015342:DNA Probes / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods* / Q000706:statistics & numerical data*; D013223:Statistics as Topic
chemical_list: D015342:DNA Probes