title: Permethylated beta-cyclodextrin in liquid poly(oxyethylene) as a stationary phase for capillary gas chromatography.
abstract: This paper reports the study of poly(oxyethylene) as a solvent for heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin (PM-beta-CD) and the potential of these mixtures for constructing enantioselective gas chromatography columns. Enantioseparations of volatile racemic mixtures using capillaries coated with 10-50% PM-beta-CD diluted in Carbowax 20M were evaluated. The influence of the polymer type on retention, separation and reproducibility over a period of time is critically discussed. The poly(oxyethylene)-based columns were also compared to columns prepared by dilution of PM-beta-CD in two polysiloxanes, SE-30 and SE-54, at several temperatures. Finally, we evaluated a new stationary phase prepared by crosslinking the chiral selector to the poly(oxyethylene) matrix.
authors.affiliation: División Química Analítica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata y CIDEPINT, 47 y 115, 1900 La Plata, Argentina.
authors.forename: Jaiver Osorio
authors.initials: JO
authors.lastname: Grisales
authors.forename: Pablo J
authors.initials: PJ
authors.lastname: Lebed
authors.forename: Sonia
authors.initials: S
authors.lastname: Keunchkarian
authors.forename: Francisco R
authors.initials: FR
authors.lastname: González
authors.forename: Cecilia B
authors.initials: CB
authors.lastname: Castells
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D008745:Methylation; D011092:Polyethylene Glycols / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D047392:beta-Cyclodextrins; D011092:Polyethylene Glycols