Serum (1-->3) beta-D-glucan as a noninvasive adjunct marker for the diagnosis of Pneumocystis pneumonia in patients with AIDS.
High serum (1-->3) beta-D-glucan levels are described in patients with Pneumocystis pneumonia (PCP). We evaluated the diagnostic value of beta-D-glucan in 111 patients with AIDS who had PCP and confirmed its usefulness. However, it does not correlate with disease severity and is not suitable for monitoring response to treatment.
Watanabe
Tamayo
T
AIDS Clinical Center, International Medical Center of Japan, Tokyo, Japan.
Yasuoka
Akira
A
Tanuma
Junko
J
Yazaki
Hirohisa
H
Honda
Haruhito
H
Tsukada
Kunihisa
K
Honda
Miwako
M
Gatanaga
Hiroyuki
H
Teruya
Katsuji
K
Kikuchi
Yoshimi
Y
Oka
Shinichi
S
D000328:Adult; D015415:Biomarkers; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011509:Proteoglycans; D047071:beta-Glucans / Q000097:blood*
D015415:Biomarkers; D011509:Proteoglycans; D047071:beta-Glucans; C010770:polysaccharide-K