title: Studies towards enantioselective surface imprinted polymers.
abstract: Molecularly imprinted polymers (MIPs) are tailor-made materials that can specifically rebind desired target molecules. Usually, the template is in solution with monomers that form a specific polymeric cavity around the template. Here, a model system with an amino acid (Fmoc-L-Histidine) is presented. This new approach entails the imprinting of templates that are bound to support materials. It is shown that the new approach leads to materials that exhibit symmetric peak shapes for both enantiomers under isocratic conditions.
authors.affiliation: MIP Technologies AB, Lund, Sweden. ecevit.yilmaz@miptechnologies.com
authors.forename: Ecevit
authors.initials: E
authors.lastname: Yilmaz
authors.forename: Johan
authors.initials: J
authors.lastname: Billing
authors.forename: Brian
authors.initials: B
authors.lastname: Boyd
authors.forename: Per
authors.initials: P
authors.lastname: Möller
authors.forename: Anthony
authors.initials: A
authors.lastname: Rees
mesh_terms: D002851:Chromatography, High Pressure Liquid; D006639:Histidine / Q000737:chemistry; D054802:Molecular Imprinting; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism; D013499:Surface Properties
chemical_list: D011108:Polymers; D006639:Histidine