Oral pulse granuloma: histological findings by confocal laser scanning microscopy.
Pulse granuloma is a rare benign entity considered to be a foreign-body reaction to vegetables particles. It occurs most frequently in the oral cavity of edentulous patients wearing a complete mobile denture, associated with impacted lower third molar or in postextractive alveolar sockets. The authors analyzed 2 cases by both optical and confocal laser scanning microscopy, a research technique based on laser light microscopic analysis of biological samples stained for fluorescence observation. CLSM allowed improved tissue imaging, bidimensional pictures with better resolution at cellular level, and, in particular, the possibility of a three-dimensional image reconstruction. In conclusion, this study reports the fine definition of pulse granuloma at microscopic level by CLSM and the results warrant the use of this technique for further analyses.
Scivetti
Michele
M
Department of Odontostomatology and Surgery, University of Bari, Bari, Italy. michele.scivetti@libero.it
Lucchese
Alberta
A
Ficarra
Giuseppe
G
Giuliani
Michele
M
Lajolo
Carlo
C
Maiorano
Eugenio
E
Favia
Gianfranco
G
D015745:Granuloma, Foreign-Body / Q000473:pathology* / Q000601:surgery; D006801:Humans; D021621:Imaging, Three-Dimensional; D018613:Microscopy, Confocal; D009059:Mouth Diseases / Q000473:pathology* / Q000601:surgery