3.3 Trovafloxacin: a case study of idiosyncratic or iatrogenic liver toxicity - molecular mechanisms and lessons for pharmacotoxicity.
Borlak
J
J
Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany. borlak@item.fraunhofer.de
D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D056486:Chemical and Drug Induced Liver Injury / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D024841:Fluoroquinolones / Q000633:toxicity*; D005786:Gene Expression Regulation / Q000187:drug effects; D005796:Genes / Q000187:drug effects; D022781:Hepatocytes / Q000187:drug effects / Q000473:pathology; D006801:Humans; D007049:Iatrogenic Disease; D009287:Naphthyridines / Q000633:toxicity*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; C080163:trovafloxacin