The role of EUTox in uremic toxin research.
In this publication, we review the activities of the European Uremic Toxin Work Group (EUTox) in the field of uremic toxin research. Founded in 1999 under the umbrella of the European Society of Artificial Organs (ESAO), and active since 2000, this group focuses essentially on questions related to solute retention and removal during chronic kidney disease, and on the deleterious impact of those solutes on biological/biochemical systems. As of January 1, 2009, the group had met 28 times; it organized the third meeting, "Uremic Toxins in Cardiovascular Disease," which took place in October 2008 in Amiens, France. The current group is composed of 25 members belonging to 23 European research institutions. As of November 1, 2008, in total 69 papers had been published to which at least two different research groups belonging to EUTox have contributed in a collaborative effort. Of these, 40 papers were on original research and eight were specific EUTox reviews or position statements. A website (http://www.eutox.info) summarizes all relevant information concerning the work group. EUTox also developed an interactive uremic toxin database, where concentrations of known toxins are displayed, to be used by researchers in the field. In the future, EUTox intends to continue its focus on bench to bedside research with specific consideration of proteomics, metabonomics, secretomics, and genomics.
Vanholder
Raymond
R
Department of Internal Medicine, Nephrology Section, University Hospital, Gent, Belgium. raymond.vanholder@ugent.be
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Omar
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Argiles
Angel
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Baurmeister
Ulrich
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Beige
Joachim
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Brouckaert
Peter
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Brunet
Philippe
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Cohen
Gerald
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De Deyn
Peter Paul
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Drüeke
Tilman B
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Fliser
Danilo
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Glorieux
Griet
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Herget-Rosenthal
Stefan
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Hörl
Walter H
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Jankowski
Joachim
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Jörres
Achim
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Massy
Ziad A
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Mischak
Harald
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Perna
Alessandra F
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Rodriguez-Portillo
Juan Mariano
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Spasovski
Goce
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Stegmayr
Bernd G
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Stenvinkel
Peter
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Thornalley
Paul J
PJ
Wanner
Christoph
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Wiecek
Andrzej
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D026683:Advisory Committees / Q000458:organization & administration*; D035843:Biomedical Research; D016208:Databases, Factual; D005060:Europe; D006801:Humans; D033181:Information Dissemination; D014118:Toxins, Biological / Q000502:physiology*; D014511:Uremia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy
D014118:Toxins, Biological