title: Obsessive-compulsive disorder: diagnostic and treatment issues.
abstract: This article reviews current issues in the diagnosis and treatment of obsessive-compulsive disorder (OCD). The introduction of the selective serotonin reuptake inhibitors and of cognitive-behavioral therapy were significant advances for treating OCD. Nevertheless, there is a need to improve awareness of OCD and its management, and to develop novel approaches to treatment-refractory patients. Although the diagnostic criteria for OCD have remained unchanged for some time, there are several areas where potential modification may be useful. There is a growing evidence base on OCD symptom dimensions and subtyping, and it is timely to consider incorporating some of these emerging data into diagnostic classification systems.
authors.affiliation: Deparment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. dan.stein@uct.ac.za
authors.forename: Dan J
authors.initials: DJ
authors.lastname: Stein
authors.forename: Damiaan
authors.initials: D
authors.lastname: Denys
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Gloster
authors.forename: Eric
authors.initials: E
authors.lastname: Hollander
authors.forename: James F
authors.initials: JF
authors.lastname: Leckman
authors.forename: Scott L
authors.initials: SL
authors.lastname: Rauch
authors.forename: Katharine A
authors.initials: KA
authors.lastname: Phillips
mesh_terms: D001921:Brain / Q000503:physiopathology; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D039721:Diagnostic and Statistical Manual of Mental Disorders; D018492:Dopamine Antagonists / Q000627:therapeutic use*; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D011613:Psychotherapy / Q000379:methods* / Q000639:trends; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
chemical_list: D018492:Dopamine Antagonists; D017367:Selective Serotonin Reuptake Inhibitors