A new liquid agent for endovascular embolization: initial clinical experience.
We developed a new water-soluble thermosensitive embolic agent, poly (N-isopropylacrylamide) and performed renal embolization in two cases with renal carcinoma by using this agent. Bleeding stopped immediately after the procedure and did not recur in follow-up intervals except fever because of postinfarction syndrome in these two patients. In one case with bilateral pulmonary metastasis, there was partial recanalization in superior segmental artery 1 month later, and this patient died 5 months after embolization due to deterioration in his general condition. The other patient refused further treatment and remained alive during 5-month follow-up interval. We believe that this agent has a great potentiality and will become a new liquid embolic material in endovascular treatment of renal carcinoma and vascular diseases.
Wang
Jianjun
J
Department of Neurosurgery, Provincial Hospital affiliated to Shandong University, Jinan, People's Republic of China.
Pang
Qi
Q
Liu
Zuoqin
Z
Sheng
Xizhong
X
D000178:Acrylamides / Q000627:therapeutic use*; D000328:Adult; D000792:Angiography; D002277:Carcinoma / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012077:Renal Artery / Q000187:drug effects / Q000473:pathology; D014656:Vascular Surgical Procedures / Q000379:methods
D000178:Acrylamides; C067295:N-isopropylacrylamide