title: [Subthreshold micropulse diode laser photocoagulation for diabetic macular edema with hard exudates].
abstract: OBJECTIVE
  To examine the efficacy of subthreshold micropulse diode laser photocoagulation (SMDLP) in eyes with diabetic macular edema (DME) with hard exudates.
  
  
  METHODS
  Ten eyes of 10 patients with diffuse DME were treated with SMDLP (810 nm). Hard exudates had accumulated within the foveal avascular zone (FAZ) in all patients. The mean retinal sensitivity within the central 10 degrees was measured with a fundus-related microperimeter (MP 1); the best corrected visual acuity (BCVA) in logMAR units and optical coherence tomography (OCT)-determined foveal thickness (FT) were recorded before and at 3 months after SMDLP.
  
  
  RESULTS
  The FT did not decrease significantly after SMDLP, but the BCVA improved significantly from 0.51 +/- 0.25 to 0.40 +/- 0.31 logMAR units (p= 0.02). There was no significant change in the mean retinal sensitivity within the central 10 degrees after SMDLP.
  
  
  CONCLUSIONS
  SMDLP can improve the visual acuity even in eyes with DME and hard exudates. However, the therapeutic efficacy of SMDLP in these cases may be limited, because no significant improvement in either the foveal thickness or retinal sensitivity could be seen.
authors.affiliation: Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Japan. koha0302atsu@graduate.chiba-u.jp
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Tatsumi
authors.forename: Miyuki
authors.initials: M
authors.lastname: Arai
authors.forename: Yoko
authors.initials: Y
authors.lastname: Takatsuna
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Mitamura
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D003930:Diabetic Retinopathy / Q000601:surgery*; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D008269:Macular Edema / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014792:Visual Acuity