Autopsy findings of a case with oxalosis.
Oxalosis, deposition of calcium oxalate in tissues, is the final stage of hyperoxaluric syndromes. Being a rare entity, it is often missed, or the diagnosis is delayed, since the definitive diagnosis requires special laboratory tests. Kidneys, the walls of blood vessels, and bones are the major sites for crystal deposition. We report the autopsy findings of a 4-year-old girl who presented with end-stage renal disease in which the clinical presentation was consistent with primary hyperoxaluria Type I. The case is unusual, as there was extensive crystal deposition throughout the body, including in tissues that are rarely involved, such as ovaries, fallopian tubes, uterus, thymus, salivary glands, pancreas, and bladder.
Doganavsargil
Basak
B
Ege University, Faculty of Medicine, Department of Pathology, Izmir, Turkey. bdoganavsargil@yahoo.com
Akil
Ipek
I
Sen
Sait
S
Mir
Sevgi
S
Basdemir
Gulcin
G
D002129:Calcium Oxalate / Q000378:metabolism*; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D007668:Kidney / Q000378:metabolism / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D008859:Microscopy, Polarization
D002129:Calcium Oxalate