A new look at detrusor underactivity: impaired contractility versus afferent dysfunction.
Detrusor underactivity (DU) is a clinical condition that describes a bladder dysfunction marked by failure of the bladder to generate sufficient contraction strength to empty over a reasonable time period. DU affects both the elderly and patients with disease processes such as diabetes mellitus. Once assumed to be a motor contractility problem, the etiology of DU now appears to be more dynamic, necessitating a new look at afferent dysfunction.
Suskind
Anne M
AM
Department of Surgery, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06034, USA.
Smith
Phillip P
PP
D000344:Afferent Pathways / Q000503:physiopathology*; D006801:Humans; D009119:Muscle Contraction; D001745:Urinary Bladder Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*