Seroprevalence of Bordetella pertussis infection during pregnancy measured by IgG antibodies against pertussis toxin.
Bordetella pertussis infection may cause severe illness in newborns. Mothers with B. pertussis infection during delivery can infect newborns. The seroprevalence of B. pertussis infection in pregnancy was measured in pregnant women by detection of immunoglobulin G against pertussis toxin; 6.3% had serological evidence of infection. Maternal vaccination should be considered to prevent pertussis in newborns.
Nooitgedagt
Judith E
JE
Department of Pediatrics, Groene Hart Ziekenhuis, Gouda. je.nooitgedagt@cukz.umcn.nl
de Greeff
Sabine C
SC
Elvers
Bert H
BH
de Melker
Hester E
HE
Notermans
Daan W
DW
van Huisseling
Hans
H
Versteegh
Florens G A
FG
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D000992:Antitoxins / Q000097:blood*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007231:Infant, Newborn; D037342:Pertussis Toxin / Q000276:immunology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D016036:Seroepidemiologic Studies; D014917:Whooping Cough / Q000453:epidemiology*; D055815:Young Adult
D000907:Antibodies, Bacterial; D000992:Antitoxins; D007074:Immunoglobulin G; D037342:Pertussis Toxin