Molecular identification and susceptibility profile in vitro of the emerging pathogen Candida kefyr.
Candida kefyr has been increasingly associated with bloodstream infections. This study reports on the identification and antifungal susceptibility pattern of 33 Candida isolates, identified biochemically as C. kefyr. One strain was finally identified as Candida sphaerica (Kluyveromyces lactis) by ITS sequencing. Both species seem to be emerging pathogens and highly susceptible in vitro to currently licensed antifungal compounds.
Gomez-Lopez
Alicia
A
Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain. aliciagl@isciii.es
Pan
Dinorah
D
Cuesta
Isabel
I
Alastruey-Izquierdo
Ana
A
Rodriguez-Tudela
Juan L
JL
Cuenca-Estrella
Manuel
M
D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects* / Q000235:genetics* / Q000472:pathogenicity; D002177:Candidiasis / Q000382:microbiology; D021901:DNA, Intergenic / Q000235:genetics; D016469:Fungemia / Q000382:microbiology; D005800:Genes, Fungal / Q000235:genetics; D006801:Humans; D007716:Kluyveromyces / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D008826:Microbial Sensitivity Tests; D017422:Sequence Analysis, DNA / Q000379:methods*
D000935:Antifungal Agents; D021901:DNA, Intergenic