Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR.
Only limited information regarding the antimicrobial susceptibilities of Mycoplasma genitalium is available because of difficulties in isolating M. genitalium strains from clinical specimens. Antimicrobial susceptibilities of 15 clinical isolates, 7 ATCC strains, and an early passage of the M30 strain were examined by the broth dilution method. Azithromycin, clarithromycin, sitafloxacin, and moxifloxacin were the most active drugs against M. genitalium, and their MIC(90)s were 0.002, 0.008, 0.125, and 0.125 mg/liter, respectively.
Hamasuna
Ryoichi
R
Department of Urology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807-8555, Japan. hamaryo@med.uoeh-u.ac.jp
Jensen
Jørgen Skov
JS
Osada
Yukio
Y
D008826:Microbial Sensitivity Tests / Q000379:methods*; D045704:Mycoplasma genitalium / Q000187:drug effects*; D016133:Polymerase Chain Reaction / Q000379:methods*