New access to trisubstituted 3-pyrrolines under phosphine catalysis.
Conjugated dienes, properly activated by electron-withdrawing groups on both ends, are shown to be suitable substrates for phosphine-promoted organocatalytic processes. Their reactions with imines, under phosphine catalysis, afford a new and efficient synthetic approach to functionalized 3-pyrrolines.
Schuler
Marie
M
Institut de Chimie des Substances Naturelles, CNRS, UPR 2301. 1, av. de la Terrasse-91198 Gif-sur-Yvette Cedex.
Duvvuru
Deepti
D
Retailleau
Pascal
P
Betzer
Jean-François
JF
Marinetti
Angela
A
D002384:Catalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D010720:Phosphines; D011758:Pyrroles; C044646:phosphine