Hyperbaric oxygen therapy for radiation-induced brain necrosis in a patient with primary central nervous system lymphoma.
A 45-year-old man who developed brain radionecrosis in the right frontal and left temporoparietal lobes after receiving whole brain radiotherapy and stereotactic radiosurgery for primary central nervous system lymphoma. Since high dose steroid treatment failed and he declined to undergo surgery, he was referred to hyperbaric oxygen (HBO) therapy. Both clinical and radiological findings improved after HBO therapy. Steroid requirements were also reduced. HBO therapy may have a potential value in treatment of brain radionecrosis.
Cihan
Yasemin Benderli
YB
Department of Radiation Oncology, Kayseri Training and Research Hospital, Kayseri, Turkey. cihany@erciyes.edu.tr
Uzun
Günalp
G
Yildiz
Senol
S
Dönmez
Halil
H
D001921:Brain / Q000473:pathology / Q000528:radiation effects*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D016371:Cranial Irradiation / Q000009:adverse effects*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008228:Lymphoma, Non-Hodgkin / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D011832:Radiation Injuries / Q000628:therapy*; D016634:Radiosurgery