title: Is the body fat of the lizard Tupinambis merianae effective against bacterial infections?
abstract: OBJECTIVE
  Tupinambis merianae is one of the animals that is most frequently used for medicinal purposes in Brazil as its body fat has many therapeutic indications in local folk medicine. This work presents the chemical compositions of the body fat of Tupinambis merianae and evaluates the antibacterial activity of the body fat as well as the ecological implications of its use in traditional medicine.
  
  
  METHODS
  Oil (OTM) was extracted from body fat located in the ventral region of Tupinambis merianae using hexane as a solvent. Fatty acids were determined indirectly using their corresponding methyl esters. The antibacterial activity of OTM was tested against standard as well as multi-resistant lines of Escherichia coli and Staphylococcus aureus, either alone or in combination with antibiotics and UV-A light.
  
  
  RESULTS
  Body fat of Tupinambis merianae presents 57% and 43% of unsaturated and saturated fatty acids respectively. Our results indicated that OTM did not demonstrate relevant antibacterial activity against any of the lines of Escherichia coli or Staphylococcus aureus, nor when combined with antibiotics or with UV-A light.
  
  
  CONCLUSIONS
  In light of these results, we recommend (i) development of management plans for a sustainable and rational use of Tupinambis merianae reducing the possible pressure on this species; and (ii) more studies be focused on the use of OTM and other natural products derived from animals that are used to treat other illnesses.
authors.affiliation: Universidade Federal da Paraíba - UFPB, Centro de Ciências Exatas e da Natureza, Departamento de Sistemática e Ecologia, Campus I, João Pessoa, PB, Brazil. ferreira fs@yahoo.com.br
authors.forename: Felipe S
authors.initials: FS
authors.lastname: Ferreira
authors.forename: Samuel V
authors.initials: SV
authors.lastname: Brito
authors.forename: José G M
authors.initials: JG
authors.lastname: Costa
authors.forename: Rômulo R N
authors.initials: RR
authors.lastname: Alves
authors.forename: Henrique D M
authors.initials: HD
authors.lastname: Coutinho
authors.forename: Waltécio de O
authors.initials: Wde O
authors.lastname: Almeida
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001424:Bacterial Infections / Q000188:drug therapy*; D001938:Brazil; D004926:Escherichia coli / Q000187:drug effects / Q000528:radiation effects; D005227:Fatty Acids / Q000032:analysis*; D008116:Lizards; D008519:Medicine, Traditional; D009821:Oils / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D013211:Staphylococcus aureus / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D009821:Oils