title: Pulsed-field gel electrophoresis, virulence determinants and antimicrobial susceptibility profiles of type Ia group B streptococci isolated from humans in Brazil.
abstract: Group B streptococci (GBS) infections occur worldwide. Although serotyping has been used for epidemiologic purposes, this does not accurately characterize enough members of a genetically heterogeneous bacterial population. The aims of this work were to evaluate the genetic diversity of 45 type Ia GBS strains isolated in Brazil by pulsed-field gel electrophoresis as well as to evaluate antimicrobial susceptibility profiles and identify virulence genes. Twenty-four strains were assigned to cluster A. All strains under study contained the hylB and scpB genes. The bca gene was detected in only 10 strains and none of the streptococci carried the bac gene. Thirty-nine strains were resistant to tetracycline.
authors.affiliation: Instituto de Microbiologia, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brasil.
authors.forename: Ana Beatriz de A
authors.initials: AB
authors.lastname: Corrêa
authors.forename: Ivi Cristina M de
authors.initials: IC
authors.lastname: Oliveira
authors.forename: Tatiana de C A
authors.initials: Tde C
authors.lastname: Pinto
authors.forename: Marcos C de
authors.initials: MC
authors.lastname: Mattos
authors.forename: Leslie C
authors.initials: LC
authors.lastname: Benchetrit
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D004279:DNA, Viral / Q000032:analysis*; D052978:Disk Diffusion Antimicrobial Tests; D016521:Electrophoresis, Gel, Pulsed-Field; D005814:Genes, Viral / Q000235:genetics*; D014644:Genetic Variation; D006801:Humans; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D004279:DNA, Viral