title: Compative study of bladder versus enteric drainage in pancreas transplantation.
abstract: BACKGROUND
  There is some controversy concerning the choice of best technique for drainage of exocrine secretions in pancreas transplantation. We compared patients with bladder drainage (BD) versus those with enteric drainage (ED).
  
  
  METHODS
  From March 1995 to September 2008, 118 patients (68 men and 50 women) of overall mean age of 37.8 +/- 7.8 years underwent pancreas transplantation. There were 109 simultaneous pancreas-kidney, and 9 pancreas after kidney procedures. Recipients were divided in a BD (n = 66 patients) and an ED group (n = 52).
  
  
  RESULTS
  Donor characteristics were similar in both groups. Thirty-two patients (48.5%) of the BD group versus none in the ED group experienced urinary tract infections (UTI; P < .001), and 16 patients (24.2%) BD versus 15 (29.4%) ED developed intraabdominal infections (P = NS). The overall rate of relaparotomies was 33.9% (n = 40): 34.8% (n = 23) in the BD versus 32.7% (n = 17) in the ED group (P = NS). Thirty patients (25.4%) lost their pancreas grafts: 21 (31.8%) in the BD group versus 9 (17.3%) in the ED group (P = .055). The acute rejection rates were 12.7%; namely, 15.2% in the BD versus 9.8% in the ED (P = NS). Three-year patient and graft survivals were equivalent in both groups: 96.1% and 65.3% in the BD versus 89.0% and 74.0% in the ED group, respectively (P = NS).
  
  
  CONCLUSIONS
  ED is a good alternative to BD for drainage of pancreatic graft exocrine secretions because both techniques have the same patient and graft survival, but BD is associated with a significantly higher rate of UTI and urologic complications.
authors.affiliation: Servicio de Cirugía General y Trasplante de Organos Abdominales, Hospital Doce de Octubre, Madrid, Spain. carlos.jimenez@inforboe.es
authors.forename: C
authors.initials: C
authors.lastname: Jiménez-Romero
authors.forename: A
authors.initials: A
authors.lastname: Manrique
authors.forename: J C
authors.initials: JC
authors.lastname: Meneu
authors.forename: F
authors.initials: F
authors.lastname: Cambra
authors.forename: A
authors.initials: A
authors.lastname: Andrés
authors.forename: J M
authors.initials: JM
authors.lastname: Morales
authors.forename: E
authors.initials: E
authors.lastname: González
authors.forename: E
authors.initials: E
authors.lastname: Hernández
authors.forename: E
authors.initials: E
authors.lastname: Morales
authors.forename: M
authors.initials: M
authors.lastname: Praga
authors.forename: E
authors.initials: E
authors.lastname: Gutierrez
authors.forename: E
authors.initials: E
authors.lastname: Moreno
mesh_terms: D000328:Adult; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery; D003928:Diabetic Nephropathies / Q000601:surgery; D004322:Drainage / Q000379:methods*; D005260:Female; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D014019:Tissue Donors / Q000706:statistics & numerical data; D001743:Urinary Bladder / Q000601:surgery*; D014552:Urinary Tract Infections / Q000453:epidemiology; D014570:Urologic Diseases / Q000453:epidemiology