title: Headache in kidney transplantation.
abstract: The aim of this retrospective study was to determine the relevance of the symptom "headache" in kidney transplanted patients, since few studies have considered headache as a clinically significant complication in this condition. A total of 83 consecutive kidney transplant patients underwent to neurological examination and a detailed headache history was taken. The headache history considered the period before kidney disease, during renal failure, during dialysis treatment and after transplantation. Diagnosis was made according to International Headache Criteria (ICDH-II) (2004). Our results reveal an occurrence of headache after kidney transplantation in 44.5% of the patients, which is higher than rates reported for the general population and in the only specific comparable study on liver transplant patients. These data suggest the need for prospective studies to explore the causal mechanisms by which headache develops with frequency in kidney transplant patients, and in particular to determine the role of immunosuppressive therapy.
authors.affiliation: Headache Centre, Department of Neurosciences, University of Padua, Via Giustiniani, 5, 35128 Padua, Italy. ferdinando.maggioni@unipd.it
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Maggioni
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Mantovan
authors.forename: Paolo
authors.initials: P
authors.lastname: Rigotti
authors.forename: Roberto
authors.initials: R
authors.lastname: Cadrobbi
authors.forename: Federico
authors.initials: F
authors.lastname: Mainardi
authors.forename: Edoardo
authors.initials: E
authors.lastname: Mampreso
authors.forename: Mario
authors.initials: M
authors.lastname: Ermani
authors.forename: Silvia
authors.initials: S
authors.lastname: Cortelazzo
authors.forename: Giorgio
authors.initials: G
authors.lastname: Zanchin
mesh_terms: D000293:Adolescent; D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects; D015984:Causality; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects; D003956:Dialysis / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D020773:Headache Disorders / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D051437:Renal Insufficiency / Q000150:complications; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone