title: Spectrofluorimetric assessment of Ramipril using optical sensor Samarium ion-doxycycline complex doped in sol-gel matrix.
abstract: A new, simple, sensitive and selective spectrofluorimetric method for the determination of Ramipril is developed. The Ramipril can remarkably quench the luminescence intensity of the Sm(3+) ion in Sm(3+)-doxycycline complex at lambda(ex)=375 nm in sol-gel matrix. In the same time the intensity of the emission band of the Ramipril in DMSO at 454 nm is increased due to the energy transfer from the Sm(3+)-doxycycline complex to Ramipril in the excited stated. The quenching of luminescence intensity of Sm(3+)-doxycycline complex doped in the sol-gel matrix and the enhancement of the emission band of Ramipril at 454 nm are directly proportion to the concentration of Ramipril with a dynamic ranges of 3.4x10(-9) - 1.0x10(-7)mol l(-1) and 2.4x10(-9) - 1.0x10(-7)mol l(-1) and detection limits of 6.0x10(-10) and 5.2x10(-10)mol l(-1), respectively.
authors.affiliation: Department of Chemistry, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt. Mohamed sam@yahoo.com
authors.forename: M S
authors.initials: MS
authors.lastname: Attia
mesh_terms: D004318:Doxycycline / Q000737:chemistry; D006801:Humans; D007202:Indicators and Reagents / Q000737:chemistry; D017257:Ramipril / Q000032:analysis*; D012493:Samarium / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013607:Tablets
chemical_list: D007202:Indicators and Reagents; D013607:Tablets; D012493:Samarium; D017257:Ramipril; D004318:Doxycycline