Granulomatous interstitial nephritis due to tuberculosis-a rare presentation.
Granulomatous interstitial nephritis (GIN) is an uncommon form of acute interstitial nephritis. We report a young male who presented to us with a rapidly progressing renal failure and massive proteinuria. A renal biopsy revealed GIN, and we were able to demonstrate the presence of tuberculous DNA in the biopsy specimen. The patient was started on anti-tuberculous therapy and steroids besides 11 sessions of hemodialysis. He recovered and is currently doing well. This case highlights an uncommon manifestation of renal tuberculosis, namely massive proteinuria, acute renal failure, and granulomatous interstitial lesions.
Sampathkumar
Krishnaswamy
K
Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Lake Area, Melur Road, Madurai, Tamil Nadu, India. drksampath@gmail.com
Sooraj
Yesudas S
YS
Mahaldar
Amol R
AR
Ramakrishnan
Muthiah
M
Rajappannair
Ajeshkumar
A
Nalumakkal
Seethalekshmy V
SV
Erode
Elango
E
D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D003131:Combined Modality Therapy; D004269:DNA, Bacterial / Q000302:isolation & purification; D004359:Drug Therapy, Combination; D006099:Granuloma / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D009395:Nephritis, Interstitial / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D011507:Proteinuria / Q000382:microbiology; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000382:microbiology; D013256:Steroids / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome; D014398:Tuberculosis, Renal / Q000150:complications / Q000382:microbiology* / Q000473:pathology / Q000628:therapy
D000995:Antitubercular Agents; D004269:DNA, Bacterial; D013256:Steroids