title: Next generation software for functional trend analysis.
abstract: FuncAssociate is a web application that discovers properties enriched in lists of genes or proteins that emerge from large-scale experimentation. Here we describe an updated application with a new interface and several new features. For example, enrichment analysis can now be performed within multiple gene- and protein-naming systems. This feature avoids potentially serious translation artifacts to which other enrichment analysis strategies are subject.
  
  
  BACKGROUND
  The FuncAssociate web application is freely available to all users at http://llama.med.harvard.edu/funcassociate.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue and Center for Cancer Systems Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.
authors.forename: Gabriel F
authors.initials: GF
authors.lastname: Berriz
authors.forename: John E
authors.initials: JE
authors.lastname: Beaver
authors.forename: Can
authors.initials: C
authors.lastname: Cenik
authors.forename: Murat
authors.initials: M
authors.lastname: Tasan
authors.forename: Frederick P
authors.initials: FP
authors.lastname: Roth
mesh_terms: D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D011506:Proteins / Q000737:chemistry; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins