Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles.
A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.
Noël
Romain
R
Department of Molecular Therapeutics and Translational Research Institute, The Scripps Research Institute, Scripps Florida, 130 Scripps Way No. A2A, Jupiter, Florida 33458, USA.
Song
Xinyi
X
Jiang
Rong
R
Chalmers
Michael J
MJ
Griffin
Patrick R
PR
Kamenecka
Theodore M
TM
D000640:Amitrole / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D000640:Amitrole