title: [Systemic lupus erythematosus and Epstein-Barr virus].
abstract: We determined the prevalence of antibodies to Epstein-Barr virus (EBV) in 44 patients with systemic lupus erythematosus (SLE) and 44 healthy blood donors matched for sex and age as controls. Of the cases, 39 were women; mean age was 33 years. Four cases (9%) and 5 controls (11%) were positive for IgM anti-viral capsid antigen (VCA) (P = 0.9). All the cases were positive for IgG anti-VCA compared with 91% of the controls (P = 0.12). The mean immunity ratio for this antibody was 2.341 in cases and 1.873 in controls (P = 0.068). Forty (91%) cases were positive for IgG anti-EBNA1 (EB nuclear antigen1) compared with 42 (95%) controls (P = 0.6).
authors.affiliation: Laboratoire d'Hématologie, CHU Ibn Rochd, Casablanca, Maroc. Tazi_illias@hotmail.com
authors.forename: I
authors.initials: I
authors.lastname: Tazi
authors.forename: S
authors.initials: S
authors.lastname: Fehri
authors.forename: K
authors.initials: K
authors.lastname: Elghrari
authors.forename: T
authors.initials: T
authors.lastname: Ouazzani
authors.forename: N
authors.initials: N
authors.lastname: Benchemsi
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000276:immunology; D036022:Capsid Proteins / Q000276:immunology; D016022:Case-Control Studies; D020031:Epstein-Barr Virus Infections / Q000097:blood / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D019309:Epstein-Barr Virus Nuclear Antigens / Q000276:immunology; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000453:epidemiology / Q000276:immunology / Q000821:virology*; D008297:Male; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D036022:Capsid Proteins; D019309:Epstein-Barr Virus Nuclear Antigens; C041788:Epstein-Barr viral capsid antigen; D007074:Immunoglobulin G; D007075:Immunoglobulin M; C417029:EBV-encoded nuclear antigen 1