title: A novel LCD (coal tar) solution for psoriasis does not discolor naturally light or color-processed hair in an exaggerated exposure test model.
abstract: BACKGROUND
  Scalp psoriasis is reported to occur in 50-80% of psoriasis sufferers. Treatment of scalp psoriasis requires special consideration of product esthetics and staining potential due to the presence of hair.
  
  
  OBJECTIVE
  To evaluate the potential of a new, marketed liquor carbonis distillate (LCD; coal tar) solution to discolor naturally light or color-processed hair under exaggerated exposure conditions.
  
  
  METHODS
  Samples of naturally light and color-processed hair from a single donor were exposed to LCD solution repeatedly over 14 days and via submergence for 24 h. Color of LCD-treated hair samples was compared with untreated control hair samples.
  
  
  RESULTS
  LCD solution did not discolor naturally light or color-processed hair following repeated exposures and 24 h submergence.
  
  
  CONCLUSIONS
  The marketed LCD solution does not appear to discolor naturally light or color-processed hair.
authors.affiliation: NeoStrata Company, Inc., Princeton, New Jersey 08540, USA.
authors.forename: Colleen
authors.initials: C
authors.lastname: Johnson
authors.forename: Brenda
authors.initials: B
authors.lastname: Edison
authors.forename: Irina
authors.initials: I
authors.lastname: Brouda
authors.forename: Barbara
authors.initials: B
authors.lastname: Green
mesh_terms: D003033:Coal Tar / Q000627:therapeutic use*; D006197:Hair / Q000187:drug effects*; D006200:Hair Color / Q000187:drug effects*; D006202:Hair Dyes / Q000494:pharmacology; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy*; D012535:Scalp / Q000187:drug effects*
chemical_list: D006202:Hair Dyes; D003033:Coal Tar