Sperm function and seminal oxidative stress as tools to identify sperm pathologies in infertile men.
Routine semen analysis, which includes assessment of sperm motility, viability, and morphology, does not always provide complete diagnostic information as men demonstrating standard scores on these specific parameters sometimes remain infertile. In infertile men who had been subgrouped on the basis of sperm count, motility, morphology, and presence of leukocytes, an evaluation of sperm function and reactive oxygen species (ROS) was found to be effective tools to detect sperm pathologies.
Ramya
T
T
Department of Reproductive Biomedicine, National Institute of Health and Family Welfare, New Delhi, India.
Misro
Man Mohan
MM
Sinha
Devabrata
D
Nandan
Deoki
D
D000975:Antioxidants / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D016022:Case-Control Studies; D002374:Catalase / Q000378:metabolism; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism* / Q000473:pathology; D007962:Leukocytes / Q000378:metabolism; D008297:Male; D018384:Oxidative Stress; D011237:Predictive Value of Tests; D017382:Reactive Oxygen Species / Q000378:metabolism*; D055101:Semen Analysis / Q000379:methods*; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000378:metabolism* / Q000473:pathology; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D015415:Biomarkers; D017382:Reactive Oxygen Species; D002374:Catalase; D013482:Superoxide Dismutase