title: Chemical composition and in vitro antibacterial activity of the essential oil of Minthostachys mollis (Kunth) Griseb Vaught from the Venezuelan Andes.
abstract: Chemical constituents of the essential oil from the leaves of Minthostachys mollis (Kunth) Griseb Vaught var. mollis collected in January 2008 at Tuñame, Trujillo State, Venezuela, were separated and identified by GC-MS analysis. The essential oil was obtained by hydrodistillation and thirteen components (98.5% of the sample) were identified by comparison with the Wiley GC-MS library data base. The two major components were pulegone (55.2%) and trans-menthone (31.5%). The essential oil showed a significant inhibitory effect against Gram-positive and Gram-negative bacteria, especially Bacillus subtilis and Salmonella typhi (4 microg/mL).
authors.affiliation: Department of Pharmacognosy and Organic Medicaments, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Médrida, Venezuela, 5101. flormv@ula.ve
authors.forename: Flor D
authors.initials: FD
authors.lastname: Mora
authors.forename: María
authors.initials: M
authors.lastname: Araque
authors.forename: Luis B
authors.initials: LB
authors.lastname: Rojas
authors.forename: Rosslyn
authors.initials: R
authors.lastname: Ramirez
authors.forename: Bladimiro
authors.initials: B
authors.lastname: Silva
authors.forename: Alfredo
authors.initials: A
authors.lastname: Usubillaga
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile