Metabolic depression during aestivation in Cyclorana alboguttata.
The green striped burrowing frog, Cyclorana alboguttata, spends, on average, nine to ten months of every year in aestivation. Recently, C. alboguttata has been the focus of much investigation regarding the physiological processes involved in aestivation, yet our understanding of this frog's capacity to metabolically depress remains limited. This study aimed to extend our current knowledge of metabolic depression during aestivation in C. alboguttata. C. alboguttata reduced whole animal metabolism by 82% within 5weeks of aestivation. The effects of aestivation on mass specific in vitro tissue metabolic rate (VO(2)) varied among individual organs, with muscle and liver slices showing significant reductions in metabolism; kidney VO(2) was elevated and there was no change in the VO(2) of small intestine tissue slices. Organ size was also affected by aestivation, with significant reductions in the mass of all tissues, except the gastrocnemius. These reductions in organ size, combined with changes in mass specific VO(2) of tissue slices, resulted in further energy savings to aestivating animals. This study shows that C. alboguttata is capable of selectively down- or up-regulating individual tissues, using both changes in metabolic rate and morphology. This strategy allows maximal energy savings during aestivation without compromising organ functionality and survival at arousal.
Kayes
Sara M
SM
School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Cramp
Rebecca L
RL
Franklin
Craig E
CE
D000818:Animals; D001481:Basal Metabolism; D004956:Estivation; D066298:In Vitro Techniques; D010101:Oxygen Consumption; D011898:Ranidae / Q000378:metabolism* / Q000502:physiology