Free transport of water and CO2 in nonporous hydrophobic clarithromycin form II crystals.
Clarithromycin is a well-known antibiotic that exists in various polymorphic forms. This molecule can be sublimed to afford a guest-free form that displays the unexpected transport of molecules of water or carbon dioxide to voids within the channel-free crystal lattice.
Tian
Jian
J
Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA.
Thallapally
Praveen K
PK
Dalgarno
Scott J
SJ
Atwood
Jerry L
JL
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002245:Carbon Dioxide / Q000737:chemistry*; D017291:Clarithromycin / Q000737:chemistry*; D018360:Crystallography, X-Ray; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D008968:Molecular Conformation; D016062:Porosity; D013696:Temperature; D014867:Water / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D014867:Water; D002245:Carbon Dioxide; D017291:Clarithromycin