A 2-arylbenzofuran derivative from Hopea mengarawan.
A new 2-arylbenzofuran derivative (diptoindonesin G) (1), along with nine known oligostilbenes, have been isolated and identified from the acetone extract of the tree bark of Hopea mengarawan. The structures of these compounds were determined based on spectroscopic data, including 2D NMR and HREIMS spectra. On cytotoxic evaluation of the isolated compounds against murin leukemia P-388 cells, compound 1 was the strongest in inhibiting the growth of the cells.
Juliawaty
Lia D
LD
Natural Products Research Group, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia.
Sahidin
Hakim
Euis H
EH
Achmad
Sjamsul A
SA
Syah
Yana M
YM
Latip
Jalifah
J
Said
Ikram M
IM
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D053958:Dipterocarpaceae / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D024301:Plant Bark / Q000737:chemistry; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
D000972:Antineoplastic Agents, Phytogenic; D001572:Benzofurans; D012997:Solvents; C543798:diptoindonesin G