title: [Relationship between body mass index and colon cancer].
abstract: OBJECTIVE
  Obesity is associated with increased risk of colorectal cancer. Many studies showed that body mass index (BMI) is related to the incidence of colon cancer. This study was to explore the relationship between BMI and colon cancer in Chinese population and provide evidences for the prevention of colon cancer.
  
  
  METHODS
  Clinical data, including BMI, of 707 colon cancer patients and 709 healthy subjects were compared.
  
  
  RESULTS
  The mean BMI was significantly higher in colon cancer patients than in healthy subjects [(24.52+/-4.56) kg/m2 vs. (23.75+/-3.14) kg/m2, t=-3.72, P<0.001]. When stratified by sex and age, the BMI was always higher in colon cancer patients than in healthy subjects. Logistic regression analyses showed that BMI was an important risk factor of colon cancer (odds ratio=1.059, 95% confidence interval=1.029-1.090).
  
  
  CONCLUSIONS
  The occurrence of colon cancer in Chinese population is related to BMI.
authors.affiliation: State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, PR China.
authors.forename: Mei-Chun
authors.initials: MC
authors.lastname: Zheng
authors.forename: Ling-Heng
authors.initials: LH
authors.lastname: Kong
authors.forename: Zhen-Hai
authors.initials: ZH
authors.lastname: Lu
authors.forename: Yu-Jing
authors.initials: YJ
authors.lastname: Fang
authors.forename: Zhi-Zhong
authors.initials: ZZ
authors.lastname: Pan
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Zhu
authors.forename: Yong-Shan
authors.initials: YS
authors.lastname: Wen
authors.forename: De-Sen
authors.initials: DS
authors.lastname: Wan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002681:China / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D016017:Odds Ratio; D012307:Risk Factors; D055815:Young Adult