Cerebral aspergillosis caused by Aspergillus granulosus.
Disseminated disease by Aspergillus granulosus has been reported only once previously in a cardiac transplant recipient. We report a fatal central nervous system infection in a lung transplant recipient. Key features of this species in the section Usti include growth at 37 degrees C and large, randomly spaced aggregates of variably shaped Hülle cells.
Sutton
Deanna A
DA
Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA. suttond@uthscsa.edu
Wickes
Brian L
BL
Romanelli
Anna M
AM
Rinaldi
Michael G
MG
Thompson
Elizabeth H
EH
Fothergill
Annette W
AW
Dishop
Megan K
MK
Elidemir
Okan
O
Mallory
George B
GB
Moonnamakal
Siby P
SP
Adesina
Adekunle M
AM
Schecter
Marc G
MG
D000293:Adolescent; D000935:Antifungal Agents / Q000494:pharmacology; D001230:Aspergillus / Q000166:cytology / Q000235:genetics / Q000302:isolation & purification*; D054022:Cerebrum / Q000382:microbiology / Q000473:pathology; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D017809:Fatal Outcome; D020459:Genes, rRNA; D006801:Humans; D016867:Immunocompromised Host; D016040:Lung Transplantation / Q000009:adverse effects; D008297:Male; D008826:Microbial Sensitivity Tests; D008853:Microscopy; D008969:Molecular Sequence Data; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000382:microbiology; D012331:RNA, Fungal / Q000235:genetics; D012339:RNA, Ribosomal, 28S / Q000235:genetics; D017422:Sequence Analysis, DNA
D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D012331:RNA, Fungal; D012339:RNA, Ribosomal, 28S