PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAalpha1) prevents the passage of tissue-type plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity.
Roussel
Benoit D
BD
Hommet
Yannick
Y
Macrez
Richard
R
Schulz
Torsten
T
Petersen
Karl-Uwe
KU
Berezowski
Vincent
V
Cecchelli
Roméo
R
Ali
Carine
C
Vivien
Denis
D
D000818:Animals; D019921:Biotinylation; D001812:Blood-Brain Barrier / Q000378:metabolism*; D002685:Chiroptera; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000628:therapy; D051379:Mice; D009474:Neurons / Q000473:pathology*; D010960:Plasminogen Activators / Q000378:metabolism*; D011994:Recombinant Proteins / Q000627:therapeutic use; D020521:Stroke / Q000628:therapy; D010959:Tissue Plasminogen Activator / Q000378:metabolism*
D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; C069588:salivary plasminogen activator alpha 1, Desmodus rotundus; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator