Clinicopathological review of tubercular laryngitis in 32 cases of pulmonary Kochs.
OBJECTIVE
The aim is to study the current clinical features of tubercular laryngitis in adult patients with pulmonary involvement in the absence of other nontubercular comorbidities.


METHODS
Medical records of histopathology confirmed cases with pulmonary Kochs in a tertiary medical center of a developing country from 1993 to 2007.


RESULTS
Thirty-two biopsy-proven cases of laryngeal tuberculosis with pulmonary involvement were found. Patients' ages ranged from 16 to 65 years. The male-to-female ratio was 4.3:1. Hoarseness of voice was the commonest symptom. Most of them were associated with advanced fibrocavitary tuberculosis of the lungs. In the larynx, multiple, granulomatous, bilateral lesions were the commonest. Most of these lesions could be reversed with appropriate antituberculous treatment.


CONCLUSIONS
Laryngeal tuberculosis with classic presentation continues to exist in developing countries. It can be the very first indication that the patient has tuberculosis. Hence, the otolaryngologist needs to remain vigilant to consider it in the differential diagnosis of chronic laryngeal disease.
Bhat
Vikram K
VK
Department of Otolaryngology, Head and Neck Surgery, Karnataka Institute of Medical Sciences, Hubli, India. vikram.ent@gmail.com
Latha
Pushpa
P
Upadhya
Divya
D
Hegde
Jyotirmay
J
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D003906:Developing Countries; D003937:Diagnosis, Differential; D005260:Female; D006685:Hoarseness / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012737:Sex Factors; D014387:Tuberculosis, Laryngeal / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D055815:Young Adult
D000995:Antitubercular Agents