title: [Non-medicamentous correction of metabolic and functional disorders in the biliary tract of patients with metabolic syndrome].
abstract: This study included 49 patients with coronary heart disease (CHD) and arterial hypertension (AH) in whom comprehensive medical examination revealed metabolic syndrome (MA). The objective of the work was to ascertain the possibility of therapy courses using chloride-hydrocarbonate-sodium mineral water and to evaluate its corrective effect on metabolic processes and functional disturbances of the biliary tract. It was shown that mineral water has beneficial effect in patients with functional incompetence of the biliary tract. Elimination of pain syndrome and resolution of dyspeptic symptoms was associated with the improvement of physico-chemical characteristics of the bile in the majority of the patients. These changes developed 1.5-2 times sooner than in the absence of therapy which substantially improved quality of life of the patients. Another positive result of mineral water consumption was the reduced level of blood lipids, in the first place that of total cholesterol and triglycerides. The efficiency of corrective action of non-medicamentous treatment modalities, such as courses of intake of chloride-hydrocarbonate-sodium mineral water, in patients with functional disturbances of the biliary tract is comparable with that of recommended drug therapy. The hypolipidemic effect of chloride-hydrocarbonate-sodium mineral water demonstrated in the present study allows it to be recommended as a tool for non-medicamentous correction of hyperlipidemia known to be not only a risk factor of CHD and AH but also as a constituent component of metabolic syndrome. The data obtained suggest the possibility to improve efficiency of the treatment of motor dysfunction of the biliary tract and metabolic disorders inherent in metabolic syndrome.
authors.forename: A B
authors.initials: AB
authors.lastname: Krivosheev
authors.forename: A D
authors.initials: AD
authors.lastname: Kuimov
authors.forename: P P
authors.initials: PP
authors.lastname: Khavin
authors.forename: A A
authors.initials: AA
authors.lastname: Morozova
mesh_terms: D000328:Adult; D000368:Aged; D001452:Balneology / Q000379:methods*; D001646:Bile / Q000737:chemistry; D001660:Biliary Tract Diseases / Q000150:complications / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy*; D001663:Bilirubin / Q000097:blood; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy*; D008875:Middle Aged; D008900:Mineral Waters / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D014783:Viscosity
chemical_list: D008900:Mineral Waters; D014280:Triglycerides; D002784:Cholesterol; D001663:Bilirubin