title: Emergence of high level azithromycin-resistant Neisseria gonorrhoeae strain isolated in Argentina.
abstract: One Neisseria gonorrhoeae strains highly resistant to azithromycin AzHLR (MIC >2048 mg/L) was isolated in Argentina in 2001 and it has been characterized by N. gonorrhoeae multiantigen sequence typing (NG-MAST) as ST696, suggesting a different event to other isolates in Europe. Neither, mtrR mutations or presence of mef gene were detected.
authors.affiliation: Centro Nacional de Referencia en Enfermedades de Transmisión Sexual (CNR-ETS), Instituto Nacional de Enfermedades Infecciosas-ANLIS Dr. Carlos G. Malbrán, 1281 Buenos Aires, Argentina. pgalarza@anlis.gov.ar
authors.forename: Patricia G
authors.initials: PG
authors.lastname: Galarza
authors.forename: Belén
authors.initials: B
authors.lastname: Alcalá
authors.forename: Celia
authors.initials: C
authors.lastname: Salcedo
authors.forename: Liliana Fernández
authors.initials: LF
authors.lastname: Canigia
authors.forename: Luis
authors.initials: L
authors.lastname: Buscemi
authors.forename: Irene
authors.initials: I
authors.lastname: Pagano
authors.forename: Claudia
authors.initials: C
authors.lastname: Oviedo
authors.forename: Julio A
authors.initials: JA
authors.lastname: Vázquez
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001118:Argentina / Q000453:epidemiology; D017963:Azithromycin / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006069:Gonorrhea / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D017963:Azithromycin