title: A case of idiopathic adulthood ductopenia.
abstract: Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology characterized by adult onset, an absence of autoantibodies, inflammatory bowel disease, and a loss of interlobular bile ducts. In the present report, a case fulfilling the IAD criteria is described. A 19-year-old man was admitted to the hospital for persistent elevation of transaminases and alkaline phosphatase without clinical symptoms. Viral hepatitis markers and autoantibodies were absent. The patient had a normal extrahepatic biliary tree and had no evidence of inflammatory bowel disease. A liver biopsy specimen showed absence of interlobular bile ducts from 58% of the portal tracts. He was diagnosed with IAD and was treated with ursodeoxycholic acid.
authors.affiliation: Department of Internal Medicine, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Korea.
authors.forename: Byeong Chool
authors.initials: BC
authors.lastname: Park
authors.forename: Seon Mee
authors.initials: SM
authors.lastname: Park
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Choi
authors.forename: Hee Bok
authors.initials: HB
authors.lastname: Chae
authors.forename: Se Jin
authors.initials: SJ
authors.lastname: Yoon
authors.forename: Rohyun
authors.initials: R
authors.lastname: Sung
authors.forename: Sung Koo
authors.initials: SK
authors.lastname: Lee
mesh_terms: D000328:Adult; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D002908:Chronic Disease; D006801:Humans; D008297:Male