title: Pregnancy and multiple sclerosis: the initial results from a Brazilian database.
abstract: OBJECTIVE
  Pregnancy management poses an extra challenge to physicians and their multiple sclerosis (MS) patients. There are few papers reporting databases on the subject.
  
  
  METHODS
  Brazilian database from nine MS clinical and research units, with complete data on 47 pregnant women (49 pregnancies).
  
  
  RESULTS
  Despite relatively high exposure to MS medications, no birth defects were reported. Low birth weight and prematurity were similar to those for developing countries. Three complications may have been associated with these medications, while three others were considered to be of purely obstetric nature.
  
  
  CONCLUSIONS
  Our results confirm previous findings on lower relapse rate during pregnancy and add to the present literature informing on data related to drug exposure.
authors.affiliation: Universidade Metropolitana de Santos, Santos, SP, Brazil. yara@bsnet.com.br
authors.forename: Yara Dadalti
authors.initials: YD
authors.lastname: Fragoso
authors.forename: Alessandro
authors.initials: A
authors.lastname: Finkelsztejn
authors.forename: Elizabeth Regina
authors.initials: ER
authors.lastname: Comini-Frota
authors.forename: Paulo Diniz
authors.initials: PD
authors.lastname: da Gama
authors.forename: Ansderson Kuntz
authors.initials: AK
authors.lastname: Grzesiuk
authors.forename: Jussara Mathias Netto
authors.initials: JM
authors.lastname: Khouri
authors.forename: Soniza Vieira
authors.initials: SV
authors.lastname: Alves-Leon
authors.forename: Rogério de Rizo
authors.initials: Rde R
authors.lastname: Morales
authors.forename: Marco Aurélio
authors.initials: MA
authors.lastname: Lana-Peixoto
authors.forename: Cristiane Franklin da
authors.initials: CF
authors.lastname: Rocha
mesh_terms: D000328:Adult; D001938:Brazil; D016208:Databases, Factual; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome