title: [Pharmaceutical therapy for the severe hemodynamic depression with carotid artery stenting].
abstract: OBJECTIVE
  To evaluate the efficacy of pharmaceutical therapy for the severe hemodynamic depression with carotid artery stenting(CAS).
  
  
  METHODS
  Clinical data were retrospectively analyzed on CAS over the last 5 years. Severe hemodynamic depression was defined as periprocedural hypotension (blood pressure <90/60 mmHg) or bradycardia (heart rate <50 beats/min) persisting for at least 1 hour. 13 patients were included in the research.
  
  
  RESULTS
  Dopamine was pumped intravenously in all the 13 patients .The dose was from 2 microg/min/kg to 10 microg/min/kg, the duration was from 4 to 48 hours. Dobutamine was used in 2 patients and dose from 5 microg/min/kg to 7 microg/min/kg, duration was from 24 to 36 hours. None of the patients developed any permanent neurological complications. One acute coronary syndrome occured during the postprocedure period.
  
  
  CONCLUSIONS
  Severe hemodynamic depression can be controlled with vasopressors (dopamine or dobutamine) and the associated complications can be prevented.
authors.affiliation: Department of Intervention and Vascular Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Min
authors.initials: M
authors.lastname: Yang
authors.forename: Li
authors.initials: L
authors.lastname: Song
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Xiao-qiang
authors.initials: XQ
authors.lastname: Tong
authors.forename: Ying-hua
authors.initials: YH
authors.lastname: Zou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001919:Bradycardia / Q000188:drug therapy* / Q000209:etiology; D016893:Carotid Stenosis / Q000628:therapy*; D004280:Dobutamine / Q000008:administration & dosage; D004298:Dopamine / Q000008:administration & dosage*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects*
chemical_list: D004280:Dobutamine; D004298:Dopamine