Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation.
Miki
Chikao
C
Gunson
Bridget K
BK
Buckels
John A C
JA
Uchida
Keiichi
K
Mohri
Yasuhiko
Y
Kusunoki
Masato
M
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001926:Brain Death / Q000503:physiopathology; D018932:Chemokine CCL2 / Q000097:blood; D004731:Endotoxins / Q000097:blood; D005260:Female; D006801:Humans; D007249:Inflammation / Q000453:epidemiology / Q000517:prevention & control; D007376:Interleukin-2 / Q000097:blood; D053645:Interleukin-2 Receptor alpha Subunit / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D007378:Interleukins / Q000097:blood; D016031:Liver Transplantation / Q000009:adverse effects / Q000276:immunology*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D011184:Postoperative Period; D015427:Reperfusion Injury / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D014019:Tissue Donors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D000893:Anti-Inflammatory Agents; D018932:Chemokine CCL2; D004731:Endotoxins; D007376:Interleukin-2; D053645:Interleukin-2 Receptor alpha Subunit; D015850:Interleukin-6; D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha; D008775:Methylprednisolone