Studies towards enantioselective surface imprinted polymers.
Molecularly imprinted polymers (MIPs) are tailor-made materials that can specifically rebind desired target molecules. Usually, the template is in solution with monomers that form a specific polymeric cavity around the template. Here, a model system with an amino acid (Fmoc-L-Histidine) is presented. This new approach entails the imprinting of templates that are bound to support materials. It is shown that the new approach leads to materials that exhibit symmetric peak shapes for both enantiomers under isocratic conditions.
Yilmaz
Ecevit
E
MIP Technologies AB, Lund, Sweden. ecevit.yilmaz@miptechnologies.com
Billing
Johan
J
Boyd
Brian
B
Möller
Per
P
Rees
Anthony
A
D002851:Chromatography, High Pressure Liquid; D006639:Histidine / Q000737:chemistry; D054802:Molecular Imprinting; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism; D013499:Surface Properties
D011108:Polymers; D006639:Histidine