[Development and validation of the first Spanish questionnaire of quality of life in patients with prostate cancer, based on the patient's perception].
BACKGROUND
To ensure health related quality of life (HRQOL) during the survival of patients with prostate cancer (PCa) is a priority. The development of specific HRQOL questionnaires aids to assess the disease impact, its treatment and the patient's perception (concerns, expectations and interests) that might go unnoticed.


OBJECTIVE
To develop and validate the first Spanish HRQL questionnaire specific for patients with PCa.


METHODS
The questionnaire CAVIPRES had 3 phases of development: 1.-generation of items (literature research, expert meeting and 2 focus groups with patients), 2.- reduction of items (self-administered survey with a preliminary version and clinimetric and psychometric analyses), 3: validation of the questionnaire (observational study with 2 visits where patients completed the CAVIPRES, SF-36 and UCLA-PCI tests and analysis of psychometric properties in terms of validity, reliability and sensitivity to change).


RESULTS
A preliminary list of 75 potential items was obtained in phase 1.412 patients were recruited and answered this preliminary version in phase 2. 35 items were deleted. 436 patients responded to the definitive-30-items obtained version (CAVIPRES-30) in Phase 3. CAVIPRES-30 showed feasibility (items lost <4%, ceiling effect: 0% floor effect: 0% in the overall score), high reliability in terms of internal consistency (alpha = 0.77) and re-test reliability (ICC = 0.92). There was a good correlation between tests CAVIPRES and SGF-36 and UCLA-PCI for similar domains


CONCLUSIONS
The questionnaire CAVIPRES-30 is a feasible, reliable and sensitive to change, useful in clinical research for prostate cancer.
Veiga
Francisco Gómez
FG
Complejo Hospitalario Universitario, A Coruña, España. fgveiga@telefonica.net
Olmo
José M Cozar
JM
Günthner
Stefan
S
Pallas
Miquel Puyol
MP
Moyano
Angel Silmi
AS
Ramos
Eva Baró
EB
Rebollo
Francisco J
FJ
D006801:Humans; D007802:Language; D008297:Male; D011471:Prostatic Neoplasms / Q000523:psychology*; D011788:Quality of Life; D011795:Surveys and Questionnaires