title: [Therapy of overactive bladder with propiverine ER: results of a non-interventional study with a propiverine retard formulation and comparison to clinical studies].
abstract: BACKGROUND
  The aim of this non-interventional study was to evaluate the efficacy and tolerability of propiverine ER under real life conditions.
  
  
  METHODS
  The treatment of 5,565 patients with urge urinary incontinence, urgency or mixed urinary incontinence was documented over a 12-week period. Incontinence episodes, voiding frequency and voided volume were recorded at 3 visits (admission, after 4 and 12 weeks). Additionally the tolerability was evaluated at visits 2 and 3.
  
  
  RESULTS
  The average incontinence episodes/24 h decreased during therapy from 4.23 to 2.89. The frequency of micturitions/24 h decreased by 5.50. The voided volume improved by 69 ml. Approximately 92 % of investigators and patients assessed the efficacy similarly with "very good" and "good". Dry mouth was the most frequent adverse drug reaction and decreased from 16.5 % after 4 weeks to 13.6 % after 12 weeks of treatment.
  
  
  CONCLUSIONS
  The efficacy and tolerability of propiverine ER were confirmed under real life conditions.
authors.affiliation: Praxis für Urologie, Greifswald, Deutschland. petra.kesslerzumpe@web.de
authors.forename: P L
authors.initials: PL
authors.lastname: Kessler-Zumpe
authors.forename: S
authors.initials: S
authors.lastname: Murgas
authors.forename: G
authors.initials: G
authors.lastname: Neumann
authors.forename: A E
authors.initials: AE
authors.lastname: Richter
mesh_terms: D000368:Aged; D001561:Benzilates / Q000009:adverse effects / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000009:adverse effects / Q000627:therapeutic use*; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*; D053202:Urinary Incontinence, Urge / Q000188:drug therapy; D014563:Urodynamics / Q000187:drug effects
chemical_list: D001561:Benzilates; D003692:Delayed-Action Preparations; D010276:Parasympatholytics; C015586:propiverine