title: Histopathological screening of tonsillectomy and/or adenoidectomy specimens: a report from southern Iran.
abstract: BACKGROUND
  The need for pathologic examination of all tonsillectomy and/or adenoidectomy (T&A) specimens is controversial. Microscopic pathologic examination of these specimens is costly, but neglecting this step may miss diagnoses of significant diseases, especially malignancies. This study was designed to determine the rate of unexpected malignancies among patients who underwent T&A.
  
  
  METHODS
  All patients who underwent T&A at Shiraz University of Medical Sciences between February 2004 and February 2008 were included in a prospective study. Gross and microscopic pathologic examinations were done on all the specimens. The charts of the patients with significant pathological finding were reviewed. Information about pre-operative signs, symptoms, and risk factors were used to verify unexpected pathologic findings.
  
  
  RESULTS
  A total of 5058 patients were included. The age distribution was 10 months to 92 years (mean 14.0 years). There were 2498 males (49.4) and 2560 females (50.6%). Significant pathological findings were detected in 54 patients (1%). One unexpected malignancy (0.019%) was found in an adult patient. No unexpected malignancies were found in pediatric patients.
  
  
  CONCLUSIONS
  All T&A specimens in the adult population should be sent for microscopic pathological examination. Also specimens of nonroutine T&A in children (with positive findings in the medical history or on physical examination) should be sent for microscopic pathological examination. In children without positive findings in their history or on physical examination, gross pathological evaluation of routine T&A specimens by a pathologist is sufficient.
authors.affiliation: Department of Otolaryngology Head-Neck Surgery, Shiraz University of Medical Sciences, Shiraz, Iran. Faramarzi@sums.ac.ir
authors.forename: A
authors.initials: A
authors.lastname: Faramarzi
authors.forename: M J
authors.initials: MJ
authors.lastname: Ashraf
authors.forename: B
authors.initials: B
authors.lastname: Hashemi
authors.forename: S T
authors.initials: ST
authors.lastname: Heydari
authors.forename: I
authors.initials: I
authors.lastname: Saif
authors.forename: N
authors.initials: N
authors.lastname: Azarpira
authors.forename: M
authors.initials: M
authors.lastname: Shishegar
authors.forename: F
authors.initials: F
authors.lastname: Eghtedari
authors.forename: B
authors.initials: B
authors.lastname: Khademi
authors.forename: M
authors.initials: M
authors.lastname: Kaviani
authors.forename: P V
authors.initials: PV
authors.lastname: Kumar
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology* / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007492:Iran; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000473:pathology*; D014066:Palatine Tonsil / Q000473:pathology* / Q000601:surgery; D014067:Tonsillar Neoplasms / Q000473:pathology*; D014068:Tonsillectomy; D055815:Young Adult