Relationship between serum butyrylcholinesterase and obesity in dogs: a preliminary report.
The aim of this study was to analyse serum butyrylcholinesterase (BChE) values in experimentally developed obesity in Beagle dogs. A short-term fattening protocol was applied to 11 dogs to obtain a wide range of bodyweight (BW) gains and body condition scores (BCS) of 4 and 5; four other dogs with BCS scores of 3 were used as controls. A significant increase in serum BChE activity in overweight dogs was observed when compared with the group of optimal weight dogs. Significant correlation was detected between BChE and BCS (r=0.911), BW (r=0.538) and morphological parameters (waist and thorax circumference, r=0.563 and r=0.552, respectively). Serum BChE concentration had a negative correlation with adiponectin concentration (r=0.719) and a positive correlation with serum lipid profile (cholesterol (r=0.781), HDL-cholesterol (r=0.763), LDL-cholesterol (r=0.878)). It was concluded that serum BChE activity is increased in experimentally overweight dogs and is correlated with other physical and biochemical markers of obesity.
Tvarijonaviciute
Asta
A
Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Murcia, 30100 Espinardo, Murcia, Spain.
Tecles
Fernando
F
Ceron
José J
JJ
D052242:Adiponectin / Q000097:blood; D000818:Animals; D015415:Biomarkers / Q000097:blood; D001824:Body Constitution; D001835:Body Weight; D002091:Butyrylcholinesterase / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs; D005260:Female; D008297:Male; D009765:Obesity / Q000097:blood / Q000662:veterinary*; D013909:Thorax / Q000033:anatomy & histology; D055105:Waist Circumference
D052242:Adiponectin; D015415:Biomarkers; D002784:Cholesterol; D002091:Butyrylcholinesterase