title: Analysis of the structural effects of four novel and a previously known mutations causing factor XI deficiency.
authors.forename: Silvia
authors.initials: S
authors.lastname: Spena
authors.forename: Rosanna
authors.initials: R
authors.lastname: Asselta
authors.forename: Sonia
authors.initials: S
authors.lastname: Caccia
authors.forename: Valeria
authors.initials: V
authors.lastname: Rimoldi
authors.forename: Sofia H
authors.initials: SH
authors.lastname: Giacomelli
authors.forename: Annarita
authors.initials: A
authors.lastname: Tagliaferri
authors.forename: Flora
authors.initials: F
authors.lastname: Peyvandi
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Castaman
authors.forename: Stefano
authors.initials: S
authors.lastname: Duga
mesh_terms: D001778:Blood Coagulation Disorders / Q000235:genetics; D004252:DNA Mutational Analysis; D005172:Factor XI / Q000235:genetics*; D005173:Factor XI Deficiency / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008958:Models, Molecular; D008968:Molecular Conformation; D009154:Mutation; D017434:Protein Structure, Tertiary; D013917:Thrombin / Q000235:genetics
chemical_list: D005172:Factor XI; D013917:Thrombin