title: [Acute toxicity of high doses of methotrexate in treatment of ALL in children: a case study].
authors.forename: L
authors.initials: L
authors.lastname: Periáñez-Párraga
authors.forename: O
authors.initials: O
authors.lastname: Pérez-Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: do Pazo-Oubiña
authors.forename: M
authors.initials: M
authors.lastname: Crespí-Monjo
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000188:drug therapy; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002648:Child; D005334:Fever / Q000139:chemically induced* / Q000188:drug therapy; D005493:Folic Acid Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D005665:Furosemide / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease; D006579:Heterozygote; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D015448:Leukemia, B-Cell / Q000188:drug therapy*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics; D020125:Mutation, Missense; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D011623:gamma-Glutamyl Hydrolase / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D005493:Folic Acid Antagonists; D005665:Furosemide; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D011623:gamma-Glutamyl Hydrolase; D002955:Leucovorin; D008727:Methotrexate