Incidence of HIV-1, syphilis, hepatitis B, and hepatitis C virus infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men in Beijing, China.
OBJECTIVE
To investigate the incidence of HIV-1, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV) infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men (MSM) in Beijing, China.


METHODS
A total of 507 eligible seronegative MSM were enrolled. Study participants were tested for HIV-1, syphilis, HBV, and HCV and counseled at the baseline, 6-month, and 12-month follow-up visits. The retention rates were analyzed as a function of demographic, behavioral, and recruitment variables.


RESULTS
Of the 507 participants, 86.2% (437) were retained in the cohort at the 12-month follow-up visit. The incidence rates were 2.6 per 100 person-years [95% confidence interval (CI): 1.1% to 4.1%] for HIV-1 infection, 16.9 per 100 person-years for syphilis (95% CI: 12.4% to 21.3%), 3.3 per 100 person-years for HBV (95% CI: 1.5% to 5.1%), and 0.2 per 100 person-years for HCV (95% CI: 0% to 0.7%). Higher education (adjusted odds ratio = 1.94, 95% CI: 1.03 to 3.66) and appearing at the 6-month follow-up visit (adjusted odds ratio = 26.15, 95% CI: 13.44 to 50.89) were significantly associated with 12-month retention.


CONCLUSIONS
HIV, syphilis, and HBV incidence are high among MSM. Intensified intervention is needed urgently. Widespread screening for HIV, syphilis, HBV, and HCV in this group should be considered as measures for control.
Ruan
Yuhua
Y
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/sexually transmitted disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing, P. R. China.
Jia
Yujiang
Y
Zhang
Xiaoxi
X
Liang
Hongyuan
H
Li
Qingchun
Q
Yang
Ye
Y
Li
Dongliang
D
Zhou
Zhenhai
Z
Luo
Fengji
F
Shi
Wei
W
Shao
Yiming
Y
D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D005500:Follow-Up Studies; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1; D006509:Hepatitis B / Q000453:epidemiology*; D006526:Hepatitis C / Q000453:epidemiology*; D018451:Homosexuality, Male; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D013587:Syphilis / Q000453:epidemiology*; D014505:Urban Population; D055815:Young Adult