Cladophialophora bantiana and Candida albicans mixed infection in cerebral abscess of an HIV-negative patient.
Cladophialophora bantiana is a black fungus recorded rarely as a cause of brain abscess. We describe the first case seen in Vietnam. A 35-year-old, previously healthy male, HIV negative, came to the hospital with a clinical diagnosis of brain tumor. He underwent surgery to remove the well-delineated circumscribed lesion. Pathology, directed physical examination and mycological examination revealed an abscess due to Cladophialophora bantiana, and Candida albicans. After two weeks of treatment with Fluconazole 400 mg per day intravenously, the clinical response remained unsatisfactory. Therapy was then withheld per the family's request.
Pham
Linh Van
LV
Department of Surgery, Hue College of Medicine and Pharmacy and University Hospital, Hue, Vietnam. phuonganh_tonnu@yahoo.com
Quang
Anh Truong
AT
Ton Nu
Phuong Anh
PA
Duc
Thai Tran
TT
Thi
Hoa Nguyen
HN
D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D001921:Brain / Q000187:drug effects / Q000382:microbiology / Q000473:pathology; D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy; D001932:Brain Neoplasms / Q000175:diagnosis; D002176:Candida albicans / Q000187:drug effects / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D015725:Fluconazole / Q000008:administration & dosage; D006261:Headache; D006429:Hemiplegia; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009181:Mycoses / Q000175:diagnosis / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy; D004718:Saccharomycetales / Q000187:drug effects / Q000302:isolation & purification*; D012640:Seizures; D017211:Treatment Failure; D014744:Vietnam
D000935:Antifungal Agents; D015725:Fluconazole