title: Recent developments and applications of microextraction techniques in drug analysis.
abstract: Sample preparation is important for isolating desired components from complex matrices and greatly influences their reliable and accurate analysis. Recent trends in sample preparation include miniaturization, automation, high-throughput performance, online coupling with analytical instruments, and low-cost operation through extremely low or no solvent consumption. Microextraction techniques, such as liquid-phase microextraction and solid-phase microextraction, have these advantages over the traditional approaches of liquid-liquid extraction and conventional solid-phase extraction. This review focuses primarily on these microextraction techniques developed over the last decade, and presents a summary of the characteristics of various approaches in drug analysis.
authors.affiliation: School of Pharmacy, Shujitsu University, Nishigawara, Okayama, 703-8516, Japan. hkataoka@shujitsu.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kataoka
mesh_terms: D002626:Chemistry, Pharmaceutical; D052617:Solid Phase Microextraction / Q000379:methods* / Q000639:trends