Two new taxoids from the leaves and stems of Taxus chinensis.
Two new taxoids called 7,13-dideacetyl-9,10-debenzoyl-7beta,9alpha-p-hydroxylbenzylidenedioxy-taxchinin C (1) and 7,13-dideacetyl-2,9,10-debenzoyl-2-tigloyl-7beta,9alpha-p-hydroxylbenzylidenedioxy-taxchinin C (2) were isolated from the leaves and stems of Taxus chinensis. They represent the first examples of taxoids containing the 5/7/6-membered ring system with 7beta,9alpha-p-hydroxylbenzylidenedioxy groups, the structures of which were elucidated based on spectroscopic analyses, especially 1D and 2D NMR spectra.
Wang
Fu-Sheng
FS
College of Pharmacy, Dali University, PR, China. fshwdl@yahoo.com.cn
Shi
Gui-Rong
GR
D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D043823:Taxoids / Q000737:chemistry* / Q000302:isolation & purification; D020946:Taxus / Q000737:chemistry*
C545021:7,13-dideacetyl-9,10-debenzoyl-7beta,9alpha-p-hydroxylbenzylidenedioxy-taxchinin C; D043823:Taxoids