Multiple system atrophy masking multiple sclerosis.
Multiple system atrophy (MSA) and multiple sclerosis (MS) are progressive neurological disorders with overlapping clinical signs and symptoms. However, due to the course of the disease and the age of onset both disorders are rarely differential diagnosis for each other. We here report the remarkable association of the two diseases in one patient. As MSA dominated the clinical presentation, diagnosis and therapy of MS were delayed. We discuss the clinical symptoms in our patient and highlight the features that allow to differentiate both diseases.
Finke
Carsten
C
Department of Neurology, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, D-10117 Berlin, Germany. carsten.finke@charite.de
Siebert
Eberhard
E
Plotkin
Michail
M
Wenning
Gregor K
GK
Reuter
Uwe
U
D000368:Aged; D004417:Dyspnea / Q000150:complications; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D019578:Multiple System Atrophy / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D009460:Neurologic Examination; D012791:Shy-Drager Syndrome / Q000209:etiology; D015899:Tomography, Emission-Computed, Single-Photon