First and convergent synthesis of hybrid sulfonophosphinopeptides.
Hybrid sulfonophosphinopeptides were first and convergently synthesized in satisfactory to good yields via the Mannich-type reaction of N-protected 2-aminoalkanesulfonamides, aromatic aldehydes, and aryldichlorophosphines and subsequent aminolysis with amino esters.
He
Fengdan
F
Department of Chemistry, Capital Normal University, Beijing100048, PR China.
Meng
Fanhua
F
Song
Xiuqing
X
Hu
Wenxiang
W
Xu
Jiaxi
J
D000447:Aldehydes / Q000737:chemistry*; D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D004952:Esters; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D010721:Phosphinic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
D000447:Aldehydes; D000596:Amino Acids; D004952:Esters; D010455:Peptides; D010721:Phosphinic Acids; D013449:Sulfonamides