1,2,4-Oxadiazole rearrangements involving an NNC side-chain sequence.
The thermal rearrangement of N-1,2,4-oxadiazol-3-yl-hydrazones into 1,2,4-triazole derivatives is reported. This represents the first example of a three-atom side-chain rearrangement involving an NNC sequence linked at the C(3) of the oxadiazole. The reactions carried out under solvent-free conditions produced good to high yields of the final products.
Piccionello
Antonio Palumbo
AP
Dipartimento di Chimica Organica E. Paternò, Università degli Studi di Palermo,Viale delle Scienze - Parco d'Orleans II, I-90128 Palermo, Italy. apalumbo@unipa.it
Pace
Andrea
A
Buscemi
Silvestre
S
Vivona
Nicolò
N