title: Seroprevalence of Bordetella pertussis infection during pregnancy measured by IgG antibodies against pertussis toxin.
abstract: Bordetella pertussis infection may cause severe illness in newborns. Mothers with B. pertussis infection during delivery can infect newborns. The seroprevalence of B. pertussis infection in pregnancy was measured in pregnant women by detection of immunoglobulin G against pertussis toxin; 6.3% had serological evidence of infection. Maternal vaccination should be considered to prevent pertussis in newborns.
authors.affiliation: Department of Pediatrics, Groene Hart Ziekenhuis, Gouda. je.nooitgedagt@cukz.umcn.nl
authors.forename: Judith E
authors.initials: JE
authors.lastname: Nooitgedagt
authors.forename: Sabine C
authors.initials: SC
authors.lastname: de Greeff
authors.forename: Bert H
authors.initials: BH
authors.lastname: Elvers
authors.forename: Hester E
authors.initials: HE
authors.lastname: de Melker
authors.forename: Daan W
authors.initials: DW
authors.lastname: Notermans
authors.forename: Hans
authors.initials: H
authors.lastname: van Huisseling
authors.forename: Florens G A
authors.initials: FG
authors.lastname: Versteegh
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D000992:Antitoxins / Q000097:blood*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007231:Infant, Newborn; D037342:Pertussis Toxin / Q000276:immunology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D016036:Seroepidemiologic Studies; D014917:Whooping Cough / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D000992:Antitoxins; D007074:Immunoglobulin G; D037342:Pertussis Toxin