title: Nucleic acid-induced aggregation and pyrene excimer formation.
abstract: Nucleic acid was found to induce the aggregation of the positively charged pyrene probe (compound 1); as a result, strong pyrene excimer emission was observed. The intensity of the excimer emission was dependent on the concentration of the pyrene probe and the oligonucleotide length, sequence, and concentration. These results suggest a new strategy for label-free nucleic acid-based biosensing applications.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Ruixing
authors.initials: R
authors.lastname: Zhang
authors.forename: Dan
authors.initials: D
authors.lastname: Tang
authors.forename: Ping
authors.initials: P
authors.lastname: Lu
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Yang
authors.forename: Dongli
authors.initials: D
authors.lastname: Liao
authors.forename: Yujing
authors.initials: Y
authors.lastname: Zhang
authors.forename: Mingjun
authors.initials: M
authors.lastname: Zhang
authors.forename: Cong
authors.initials: C
authors.lastname: Yu
authors.forename: Vivian W W
authors.initials: VW
authors.lastname: Yam
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D009696:Nucleic Acids / Q000737:chemistry*; D011721:Pyrenes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D009696:Nucleic Acids; D011721:Pyrenes; C030984:pyrene