title: [Highly efficient chemoprophylaxis of perinatal transmission of HIV 1 infection in HIV-infected pregnant women].
abstract: Prevention of HIV infection perinatal transmission with specific anti-HIV agents is at present effective and resultant. The use of retrovir and nevirapin in such cases is well known and approved. The Russian anti-HIV drug nicavir (phosphazide) also proved its high efficacy, that was evident from the results of its use in chemoprophylaxis of perinatal HIV infection transmission in HIV-infected pregnant women. The discussion of the results is presented.
authors.forename: G A
authors.initials: GA
authors.lastname: Galegov
mesh_terms: D000818:Animals; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D001386:Azides / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D051379:Mice; D019829:Nevirapine / Q000627:therapeutic use*; D063065:Organophosphonates / Q000627:therapeutic use*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control* / Q000821:virology; D011817:Rabbits; D051381:Rats; D013607:Tablets; D013936:Thymidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: C405002:3'-azido-3'-deoxythymidine-5'-H-phosphonate; D019380:Anti-HIV Agents; D001386:Azides; D063065:Organophosphonates; D013607:Tablets; D019829:Nevirapine; D013936:Thymidine