title: Unexpected preferential dehydration of artemisinin in ionic liquids.
abstract: Thermodynamic measurements (at 298 K) reveal that a crucial step in the extraction process of the key antimalarial drug artemisinin by ionic liquids (ILs), namely, precipitation through the addition of water, is driven by artemisinin dehydration due to the differences in the water's interaction with the bulk ILs, rather than with the artemisinin itself.
authors.forename: Marc W
authors.initials: MW
authors.lastname: Sanders
authors.forename: Lawrence
authors.initials: L
authors.lastname: Wright
authors.forename: Lauren
authors.initials: L
authors.lastname: Tate
authors.forename: Gayle
authors.initials: G
authors.lastname: Fairless
authors.forename: Lorna
authors.initials: L
authors.lastname: Crowhurst
authors.forename: Neil C
authors.initials: NC
authors.lastname: Bruce
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Walker
authors.forename: Guy A
authors.initials: GA
authors.lastname: Hembury
authors.forename: Seishi
authors.initials: S
authors.lastname: Shimizu
mesh_terms: D037621:Artemisinins / Q000737:chemistry*; D003681:Dehydration; D052578:Ionic Liquids / Q000737:chemistry*; D013816:Thermodynamics; D014867:Water / Q000737:chemistry
chemical_list: D037621:Artemisinins; D052578:Ionic Liquids; D014867:Water; C031327:artemisinin