title: Ventricular tachycardia during hyperthermic intraperitoneal chemotherapy.
abstract: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is used for selected gastrointestinal carcinomas. We report a case of ventricular tachycardia during HIPEC with cisplatin that persisted as long as the chemotherapy solution remained in the intra-abdominal cavity. We hypothesise that high plasma levels of cisplatin with concomitant low magnesium levels caused the arrhythmia.
authors.affiliation: Department of Anaesthesiology and Critical Care Medicine, Tuebingen University Hospital, Tuebingen, Germany.
authors.forename: C A
authors.initials: CA
authors.lastname: Thix
authors.forename: I
authors.initials: I
authors.lastname: Königsrainer
authors.forename: R
authors.initials: R
authors.lastname: Kind
authors.forename: P
authors.initials: P
authors.lastname: Wied
authors.forename: T H
authors.initials: TH
authors.lastname: Schroeder
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007263:Infusions, Parenteral; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D017180:Tachycardia, Ventricular / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin