title: Polyester connecting ring improves outcome in nitinol composite artificial esophagus.
abstract: In a previous study, we replaced a thoracic esophagus with nitinol composite artificial esophagus. Two major problems of anastomotic leakage and early sloughing of the grafted prostheses were noted. We have developed a new type of nitinol composite artificial esophagus with polyester connecting ring, and in this study, we test the effectiveness of replacing a thoracic esophagus with this new type of tube. We experimented with two groups: with polyester connecting ring (experimental) and without (control). The shedding time of artificial esophagus in the experimental group was significantly delayed compared with the control group (127.2 +/- 51.8 days vs. 27.6 +/- 15.7 days, respectively, p < 0.05). The incidence of the two major postoperative complications in the experimental group was significantly decreased compared with the control group: anastomotic leakage (0% vs. 33.3%, respectively, p < 0.05) and severe neoesophageal stenosis after prostheses sloughing (10% vs. 50%, respectively, p < 0.05). The long-term survival rate (>6 months) in the experimental group was significantly increased compared with the control group (100% vs. 10%, respectively, p < 0.05). These results suggest that the polyester connecting ring improves outcome of replacement of the thoracic esophagus with nitinol composite artificial esophagus.
authors.affiliation: Department of Chest Surgery, the Second Affiliated Hospital of Guangzhou Medical College, Institute of Guangzhou Cardiovascular Diseases, Guangzhou, China. liangJH2006@163.com
authors.forename: Jian-hui
authors.initials: JH
authors.lastname: Liang
authors.forename: Xing
authors.initials: X
authors.lastname: Zhou
authors.forename: Zhao-bing
authors.initials: ZB
authors.lastname: Zheng
authors.forename: Xian-liang
authors.initials: XL
authors.lastname: Liang
mesh_terms: D000497:Alloys; D000714:Anastomosis, Surgical / Q000295:instrumentation; D000818:Animals; D001187:Artificial Organs; D004947:Esophagus / Q000601:surgery*; D020007:Implants, Experimental / Q000009:adverse effects; D011091:Polyesters; D011183:Postoperative Complications / Q000209:etiology; D013552:Swine
chemical_list: D000497:Alloys; D011091:Polyesters; C013616:nitinol