[Mirtazapine--pharmacologic action and clinical advantages].
Mirtazapine is an effective antidepressant with unique and special mechanism of action characterized by high response and remission rates, relatively early onest of action and favourable side-effect profile. The present paper reviews some special points of the clinical use of mirtazapine, which is on the market in Hungary for almost 10 years, including its sleep-improving and anxiolytic effets. This review will also touch the management of the most commonly occuring side-effects.
Rihmer
Zoltán
Z
Semmelweis Egyetem, Klinikai es Kutatási Mentá lhigiéné s Osztály, Budapest. rihmerz@kut.sote.hu
Purebl
György
G
D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D003863:Depression / Q000188:drug therapy; D003865:Major Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D008803:Mianserin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D000078785:Mirtazapine; D012890:Sleep / Q000187:drug effects*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012895:Sleep, REM / Q000187:drug effects; D013405:Suicide; D016896:Treatment Outcome
D000317:Adrenergic alpha-Antagonists; D014151:Anti-Anxiety Agents; D018687:Antidepressive Agents, Second-Generation; D008803:Mianserin; D000078785:Mirtazapine