title: Facile synthesis of 1,1-difluoroallenes via the difluorovinylidenation of aldehydes and ketones.
abstract: 2-Bromo-3,3-difluoroallylic acetates were readily prepared by the reaction of carbonyl compounds with 1-bromo-2,2-difluorovinyllithium, generated from 1,1-dibromo-2,2-difluoroethylene, followed by acetylation. On treatment with butyllithium, the bromoacetates underwent selective 1,2-elimination of lithium acetate to afford mono- and disubstituted 1,1-difluoroallenes in high yields.
authors.affiliation: Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8571, Japan.
authors.forename: Misaki
authors.initials: M
authors.lastname: Yokota
authors.forename: Kohei
authors.initials: K
authors.lastname: Fuchibe
authors.forename: Mikiko
authors.initials: M
authors.lastname: Ueda
authors.forename: Yuka
authors.initials: Y
authors.lastname: Mayumi
authors.forename: Junji
authors.initials: J
authors.lastname: Ichikawa