title: Chiral amidophosphane-rhodium(i)-catalyzed asymmetric conjugate arylation of acyclic enones with arylboronic acids.
abstract: A catalytic asymmetric conjugate arylation of acyclic alpha,beta-unsaturated ketones with arylboronic acids was catalyzed by 3 mol% of chiral amidomonophosphane 1-rhodium(I) in the presence of potassium hydroxide in a mixture of 1,4-dioxane and water at 70 degrees C to afford 1,4-conjugate arylated acyclic ketones with high enantiomeric excess in high chemical yield. Thirteen examples of the reaction demonstrate the general applicability of the catalytic system.
authors.affiliation: The Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.forename: Masami
authors.initials: M
authors.lastname: Kuriyama
authors.forename: Xinyu
authors.initials: X
authors.lastname: Hao
authors.forename: Takahiro
authors.initials: T
authors.lastname: Soeta
authors.forename: Yasutomo
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Yamada
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tomioka
mesh_terms: D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D007659:Ketones / Q000737:chemistry; D010720:Phosphines / Q000138:chemical synthesis / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D007659:Ketones; D010720:Phosphines; D012238:Rhodium