title: EANM-EORTC general recommendations for sentinel node  diagnostics in melanoma.
abstract: The accurate diagnosis of a sentinel node in melanoma includes a sequence of procedures from different medical specialities (nuclear medicine, surgery, oncology, and pathology). The items covered are presented in 11 sections and a reference list: (1) definition of a sentinel node, (2) clinical indications, (3) radiopharmaceuticals and activity injected, (4) dosimetry, (5) injection technique, (6) image acquisition and interpretation, (7) report and display, (8) use of dye, (9) gamma probe detection, (10) surgical techniques in sentinel node biopsy, and (11) pathological evaluation of melanoma-draining sentinel lymph nodes. If specific recommendations given cannot be based on evidence from original, scientific studies, referral is given to "general consensus" and similar expressions. The recommendations are designed to assist in the practice of referral to, performance, interpretation and reporting of all steps of the sentinel node procedure in the hope of setting state-of-the-art standards for good-quality evaluation of possible spread to the lymphatic system in intermediate-to-high risk melanoma without clinical signs of dissemination.
authors.affiliation: Department of Plastic Surgery and Burns Unit, Rigshospitalet, Copenhagen, Denmark. annette.hougaard.chakera@live.dk
authors.forename: Annette H
authors.initials: AH
authors.lastname: Chakera
authors.forename: Birger
authors.initials: B
authors.lastname: Hesse
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Burak
authors.forename: James R
authors.initials: JR
authors.lastname: Ballinger
authors.forename: Allan
authors.initials: A
authors.lastname: Britten
authors.forename: Corrado
authors.initials: C
authors.lastname: Caracò
authors.forename: Alistair J
authors.initials: AJ
authors.lastname: Cochran
authors.forename: Martin G
authors.initials: MG
authors.lastname: Cook
authors.forename: Krzysztof T
authors.initials: KT
authors.lastname: Drzewiecki
authors.forename: Richard
authors.initials: R
authors.lastname: Essner
authors.forename: Einat
authors.initials: E
authors.lastname: Even-Sapir
authors.forename: Alexander M M
authors.initials: AM
authors.lastname: Eggermont
authors.forename: Tanja Gmeiner
authors.initials: TG
authors.lastname: Stopar
authors.forename: Christian
authors.initials: C
authors.lastname: Ingvar
authors.forename: Martin C
authors.initials: MC
authors.lastname: Mihm
authors.forename: Stanley W
authors.initials: SW
authors.lastname: McCarthy
authors.forename: Nicola
authors.initials: N
authors.lastname: Mozzillo
authors.forename: Omgo E
authors.initials: OE
authors.lastname: Nieweg
authors.forename: Richard A
authors.initials: RA
authors.lastname: Scolyer
authors.forename: Hans
authors.initials: H
authors.lastname: Starz
authors.forename: John F
authors.initials: JF
authors.lastname: Thompson
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Trifirò
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Viale
authors.forename: Sergi
authors.initials: S
authors.lastname: Vidal-Sicart
authors.forename: Roger
authors.initials: R
authors.lastname: Uren
authors.forename: Wendy
authors.initials: W
authors.lastname: Waddington
authors.forename: Arturo
authors.initials: A
authors.lastname: Chiti
authors.forename: Alain
authors.initials: A
authors.lastname: Spatz
authors.forename: Alessandro
authors.initials: A
authors.lastname: Testori
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D000075202:Contraindications; D005260:Female; D006801:Humans; D007223:Infant; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008545:Melanoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000000981:diagnostic imaging; D011835:Radiation Protection; D019275:Radiopharmaceuticals; D021701:Sentinel Lymph Node Biopsy / Q000295:instrumentation / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals