[Influence of active forms of oxygen on antilysozyme activity of bacteria].
OBJECTIVE
To study the effect of active forms of oxygen on bacterial population structure on antilysozyme characteristic.


METHODS
Antilysozyme activity of bacterial clones obtained after their treatment by hydrogen peroxide and hydroxyl radical in sublethal (LD10) and non-lethal concentrations.


RESULTS
Shift of bacterial population structure in direction to increased proportion of clones with high level of antilysozyme activitywith elevating average population level of this characteristic under the influence of sublethal (LD10) concentrations of hydrogen peroxide and hydroxyl radical was established. Using of non-lethal concentrations of active forms of oxygen resulted in decrease of average population level of antilysozyme activity and emergence of clones with lower level of expression of this characteristic than in control population.


CONCLUSIONS
It was assumed that active forms of oxygen provide variety of types of interaction of microorganisms with each other and with macroorganism due to change of intrapopulation heterogeneity of biological characteristics of bacteria, which enables them to realize their persistence potential.
Sgibnev
A V
AV
Cherkasov
S V
SV
D004926:Escherichia coli / Q000187:drug effects / Q000472:pathogenicity*; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism* / Q000494:pharmacology; D017665:Hydroxyl Radical / Q000378:metabolism* / Q000494:pharmacology; D009113:Muramidase / Q000037:antagonists & inhibitors*; D010100:Oxygen / Q000378:metabolism / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000472:pathogenicity*
D017665:Hydroxyl Radical; D006861:Hydrogen Peroxide; D009113:Muramidase; D010100:Oxygen