title: SAD kinase keeps centrosomes lonely.
abstract: Centrosome duplication is under strict control such that it occurs only once per cell cycle. New insights into the molecular mechanisms that control centrosome number come from the discovery of a role for SADB kinase in centrosome biogenesis.
authors.forename: Daici
authors.initials: D
authors.lastname: Chen
authors.forename: Jackie
authors.initials: J
authors.lastname: Vogel
mesh_terms: D000818:Animals; D018385:Centrosome / Q000201:enzymology*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008954:Models, Biological; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014404:Tubulin / Q000737:chemistry / Q000378:metabolism
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D014404:Tubulin; D010768:Phosphoserine; C523084:BRSK1 protein, human; C496826:Brsk1 protein, mouse; D017346:Protein Serine-Threonine Kinases