Dynamic behavior of giant liposomes at desired osmotic pressures.
To apply accurate and uniform osmotic pressures to liposomes, they can be formed using the spontaneous transfer method in solutions with different osmolarities. The majority of liposomes unexpectedly opened large holes (several micrometers in diameter) in response to the osmotic pressure regardless of its strength, that is, the difference between the outside and inside solute (sucrose or KCl) concentrations. However, the lag time for any response, including the opening of a hole, after the formation of the liposome decreased with increasing osmotic pressure.
Ohno
Masae
M
Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
Hamada
Tsutomu
T
Takiguchi
Kingo
K
Homma
Michio
M
D008081:Liposomes / Q000737:chemistry*; D009997:Osmotic Pressure; D011189:Potassium Chloride / Q000737:chemistry; D012996:Solutions; D013395:Sucrose / Q000737:chemistry; D013997:Time Factors; D014867:Water / Q000737:chemistry
D008081:Liposomes; D012996:Solutions; D014867:Water; D013395:Sucrose; D011189:Potassium Chloride