title: Recurrent hoarseness due to inflammatory vocal fold lesions in a patient with Crohn's disease.
abstract: Crohn's disease is a chronic inflammatory bowel disease characterized by discontinuous chronic inflammation that may affect virtually all organs, including the head and neck. Laryngeal involvement in Crohn's disease is very rare, and only 9 cases have been reported. All 9 patients complained of difficulty in breathing due to edema and ulceration from the larynx to the hypopharynx. The present patient was a 31-year-old woman who had experienced the intestinal symptoms of Crohn's disease starting 20 months earlier and complained of hoarseness, sore throat, and odynophagia. The hoarseness worsened gradually because of limited ulceration of the vocal fold without edema. We describe the first case in which limited ulceration occurred on the vocal fold without airway involvement.
authors.affiliation: Division of Otolaryngology, Social Insurance Central General Hospital, Tokyo, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Hasegawa
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Ishimoto
authors.forename: Masakazu
authors.initials: M
authors.lastname: Takazoe
authors.forename: Koichi
authors.initials: K
authors.lastname: Tsunoda
authors.forename: Youko
authors.initials: Y
authors.lastname: Fujimaki
authors.forename: Aiko
authors.initials: A
authors.lastname: Shiraishi
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Kazunari
authors.initials: K
authors.lastname: Okada
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications / Q000473:pathology* / Q000628:therapy; D005260:Female; D006685:Hoarseness / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D012008:Recurrence; D014827:Vocal Cords / Q000473:pathology*