A new iridoid glycoside from Scrophularia ningpoensis.
A new iridoid glycoside, named 6'-O-cinnamoylharpagide (1), has been isolated from the roots of Scrophularia ningpoensis (Scrophulariaceae) together with nine known compounds, harpagide (2), harpagoside (3), 8-O-feruloylharpagide (4), 8-O-(p-coumaroyl)harpagide (5), 6-O-methylcatalpol (6), aucubin (7), buergerinin B (8), teuhircoside (9) and 6-O-cinnamoyl-D-glucopyranose (10). Compound 10 was obtained as an inseparable mixture of 6-O-cinnamoyl-alpha-D-glucopyranose and 6-O-cinnamoyl-beta-D-glucopyranose at a ratio of 1 : 1, which is presumably formed by cleavage of compound 1. Their structures were elucidated on the basis of chemical and spectral analysis.
Niu
Zheng-Rui
ZR
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Centre, Beijing, P.R. China.
Wang
Ru-Feng
RF
Shang
Ming-Ying
MY
Cai
Shao-Qing
SQ
D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry*; D039823:Iridoids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D032266:Scrophularia / Q000737:chemistry*
D006027:Glycosides; D039823:Iridoids