High gene expression of MDR1 (ABCB1) is associated with medical treatment response and long-term remission in patients with ulcerative colitis.
Yamamoto-Furusho
Jesús K
JK
Villeda-Ramírez
Marco A
MA
Fonseca-Camarillo
Gabriela
G
Sánchez-Muñoz
Fausto
F
Dominguez-Lopez
Aarón
A
Barreto-Zuñiga
Rafael
R
Uribe
Misael
M
D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D016022:Case-Control Studies; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015850:Interleukin-6 / Q000235:genetics / Q000378:metabolism; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D012074:Remission Induction; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016896:Treatment Outcome
C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D015850:Interleukin-6; D012333:RNA, Messenger; D001379:Azathioprine; D011241:Prednisone