title: Therapeutic failure in a renal transplant patient with Pneumocystis jiroveci pneumonia: a case report.
abstract: OBJECTIVE
  Pneumocystis jiroveci pneumonia is common in immunocompromised individuals.
  
  
  METHODS
  This case report describes an immunosuppressed patient who acquired P jiroveci pneumonia 6 months after renal transplant surgery.
  
  
  RESULTS
  The patient experienced many pneumonia-related complications and adverse effects from drug therapy, and despite treatment with various antibiotic agents, he died on the 62nd day after his admission to the intensive care unit.
  
  
  CONCLUSIONS
  The therapeutic failure of the drug of choice (co-trimoxazole) was evident. This case raises questions about the development of P jiroveci resistance to current therapies.
authors.affiliation: Intensive Care Unit, Laiko General Hospital, Aretaieio Hospital, 11528 Athens, Greece.
authors.forename: Nikolaos K
authors.initials: NK
authors.lastname: Archontoulis
authors.forename: Chryssoula V
authors.initials: CV
authors.lastname: Staikou
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D045363:Pneumocystis carinii / Q000472:pathogenicity*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000276:immunology; D017211:Treatment Failure; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination