Ximaosteroids A-D, new steroids from the Hainan soft coral Scleronephthya sp.
One novel uncommon steroid, ximaosteroid A (1), possessing an unusual tetrahydrofuran moiety and three new pregnane steroids, ximaosteroids B-D (2-4), were isolated from the Hainan soft coral Scleronephthya sp. Their structures were elucidated on the basis of detailed spectroscopic (IR, MS, and 2D NMR) analysis and by comparison with those reported in the literature.
Yan
Xiao-Hong
XH
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhang Jiang High-Tech Park, Shanghai, PR China.
Liu
Hai-Li
HL
Guo
Yue-Wei
YW
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D045744:Cell Line, Tumor; D005663:Furans / Q000737:chemistry*; D006801:Humans; D051379:Mice; D011278:Pregnanes / Q000737:chemistry* / Q000494:pharmacology
D000970:Antineoplastic Agents; D005663:Furans; D011278:Pregnanes; C018674:tetrahydrofuran