Metabolism by remote control.
Drosophila melanogaster produce insulin-like peptides in specialized neuroendocrine cells to regulate growth, metabolism, aging, and reproduction. In this issue of Cell Metabolism, Géminard et al. (2009) describe how secretion of insulin-like peptides is remotely controlled by the fat body (an adipose, liver-like tissue) in response to dietary amino acids.
Tatar
Marc
M
Brown University, Providence, RI 02912, USA. marc_tatar@brown.edu
D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000378:metabolism*; D050417:Insulin-Secreting Cells / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D009479:Neuropeptides / Q000378:metabolism*
D029721:Drosophila Proteins; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; C518293:raptor protein, Drosophila