Measurements of neutron distribution in neutrons-gamma-rays mixed field using imaging plate for neutron capture therapy.
The imaging plate (IP) technique is tried to be used as a handy method to measure the spatial neutron distribution via the (157)Gd(n,gamma)(158)Gd reaction for neutron capture therapy (NCT). For this purpose, IP is set in a water phantom and irradiated in a mixed field of neutrons and gamma-rays. The Hiroshima University Radiobiological Research Accelerator is utilized for this experiment. The neutrons are moderated with 20-cm-thick D(2)O to obtain suitable neutron field for NCT. The signal for IP doped with Gd as a neutron-response enhancer is subtracted with its contribution by gamma-rays, which was estimated using IP without Gd. The gamma-ray response of Gd-doped IP to non-Gd IP is set at 1.34, the value measured for (60)Co gamma-rays, in estimating the gamma-ray contribution to Gd-doped IP signal. Then measured distribution of the (157)Gd(n,gamma)(158)Gd reaction rate agrees within 10% with the calculated value based on the method that has already been validated for its reproducibility of Au activation. However, the evaluated distribution of the (157)Gd(n,gamma)(158)Gd reaction rate is so sensitive to gamma-ray energy, e.g. the discrepancy of the (157)Gd(n,gamma)(158)Gd reaction rate between measurement and calculation becomes 30% for the photon energy change from 33keV to 1.253MeV.
Tanaka
Kenichi
K
Center of Medical Education, Sapporo Medical University, 17, Minami 1 Jo, Chuo-ku, Sapporo 060-8556, Japan. tanakaken@sapmed.ac.jp
Endo
Satoru
S
Hoshi
Masaharu
M
D003198:Computer Simulation; D005682:Gadolinium; D005720:Gamma Rays; D007554:Isotopes; D017247:Neutron Capture Therapy / Q000295:instrumentation / Q000379:methods*; D009502:Neutrons; D019047:Phantoms, Imaging; D011868:Radioisotopes
D007554:Isotopes; D011868:Radioisotopes; D005682:Gadolinium