title: [Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps].
abstract: OBJECTIVE
  To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps.
  
  
  METHODS
  Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age.
  
  
  RESULTS
  Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps.
  
  
  CONCLUSIONS
  Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.
authors.forename: I I
authors.initials: II
authors.lastname: Dolgushin
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Andreeva
authors.forename: A I
authors.initials: AI
authors.lastname: Ryzhkova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Savochkina
authors.forename: E A
authors.initials: EA
authors.lastname: Mezentseva
authors.forename: K V
authors.initials: KV
authors.lastname: Nikushkina
authors.forename: O S
authors.initials: OS
authors.lastname: Abramovskikh
authors.forename: S I
authors.initials: SI
authors.lastname: Marachev
authors.forename: D N
authors.initials: DN
authors.lastname: Matveeva
mesh_terms: D000328:Adult; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D009092:Mucous Membrane / Q000276:immunology; D009504:Neutrophils / Q000276:immunology* / Q000648:ultrastructure; D014621:Vagina / Q000276:immunology
chemical_list: D001428:Bacterial Vaccines; C039045:SolcoTrichovac