Successful pregnancy in an ovarian agenesis patient after modified natural cycle IVF oocyte donation.
The recovery of a mature oocyte from a modified natural cycle followed by in-vitro fertilization (nIVF) is an attractive alternative to conventional IVF, involving ovarian stimulation, in the treatment of female infertility. Ovarian agenesis is a rare disorder resulting in primary amenorrhoea and infertility in affected females. A couple sought help for infertility due to ovarian agenesis of the female partner and decided to pursue treatment utilizing oocyte donation. Modified natural-cycle egg retrieval was carried out on the donor; one mature oocyte was retrieved and underwent IVF using a sperm sample from the male partner. A good-quality embryo was transferred, A viable pregnancy was confirmed by ultrasound scan and resulted in the delivery of a healthy baby boy at 36 weeks' gestation. This is the second published report of an ongoing clinical pregnancy and subsequent birth resulting from oocyte donation recovered during a modified natural cycle. The use of less invasive assisted reproduction techniques such as nIVF can be used in oocyte donation cycles successfully.
Kadoch
Isaac Jacques
IJ
University of Montreal, Department of Obstetrics and Gynecology, Saint Luc Hospital (CHUM), 1058 rue Saint-Denis, Montreal, Québec, Canada. ij.kadoch@umontreal.ca
Jamal
Wael
W
Phillips
Simon J
SJ
Hemmings
Robert
R
Lapensée
Louise
L
Couturier
Bernard
B
Bissonnette
François
F
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D009865:Oocytes; D010053:Ovary / Q000473:pathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D014019:Tissue Donors