Sugar perception and signaling--an update.
Sugars act as potent signaling molecules in plants. Several sugar sensors, including the highly studied glucose sensor HEXOKINASE1 (HXK1), have been identified or proposed. Many additional sensors likely exist, as plants respond to other sugars and sugar metabolites, such as sucrose and trehalose 6-phosphate. Sugar sensing and signaling is a highly complex process resulting in many changes in physiology and development and is integrated with other signaling pathways in plants such as those for inorganic nutrients, hormones, and different stress factors. Importantly, KIN10 and KIN11 protein kinases are central in coordinating several of the responses to sugars and stress. bZIP transcription factors were found to mediate effects of sugar signaling on gene expression and metabolite content.
Hanson
Johannes
J
Department of Molecular Plant Physiology, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands. s.j.hanson@uu.nl
Smeekens
Sjef
S
D050976:Basic-Leucine Zipper Transcription Factors / Q000378:metabolism; D050260:Carbohydrate Metabolism; D018506:Gene Expression Regulation, Plant; D006593:Hexokinase / Q000378:metabolism; D063245:Plant Development; D010940:Plant Proteins / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D013395:Sucrose / Q000378:metabolism; D013403:Sugar Phosphates / Q000378:metabolism; D014199:Trehalose / Q000031:analogs & derivatives / Q000378:metabolism
D050976:Basic-Leucine Zipper Transcription Factors; D010940:Plant Proteins; D013403:Sugar Phosphates; C082722:trehalose-6-phosphate; D013395:Sucrose; D014199:Trehalose; D006593:Hexokinase