title: Neurofibromatosis 1 and dental caries.
abstract: A total of 110 patients with neurofibromatosis 1 (NF1) were evaluated for their dental health. Appropriate cohorts from national Finnish databases were used as reference. The results showed that NF1 patients presented lower rate of caries compared to controls in age groups under 35 years. The differences between NF1 patients and the reference population diminished by age. In conclusion, (1) NF1 per se does not predispose to caries; and (2) even if NF1 had an adverse effect on dental health, poor outcome can be counteracted with good personal dental care supported by well organized primary health care. The results of the present study are important to report since a common anecdotal perception is that the rate of caries may be higher in NF1 compared to reference population.
authors.affiliation: Department of Cell Biology and Anatomy, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. vivvis@utu.fi
authors.forename: Vivian
authors.initials: V
authors.lastname: Visnapuu
authors.forename: Kaisu
authors.initials: K
authors.lastname: Pienihäkkinen
authors.forename: Sirkku
authors.initials: S
authors.lastname: Peltonen
authors.forename: Risto-Pekka
authors.initials: RP
authors.lastname: Happonen
authors.forename: Juha
authors.initials: J
authors.lastname: Peltonen
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries / Q000150:complications*; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications*; D009909:Oral Health; D055815:Young Adult