title: Familial hypercholesterolaemia: different perspectives.
abstract: Familial hypercholesterolaemia is a genetic condition characterised by high cholesterol levels in the blood and an increased risk of premature coronary heart disease. In this article, the authors review the clinical features, pathology, epidemiology and clinical management of this often underdiagnosed condition.
authors.affiliation: Royal Brompton and Harefield NHS Trust, Middlesex.
authors.forename: Jane L
authors.initials: JL
authors.lastname: Jones
authors.forename: Edin
authors.initials: E
authors.lastname: Lakasing
authors.forename: Stefanos
authors.initials: S
authors.lastname: Archontakis
mesh_terms: D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001384:Azetidines / Q000627:therapeutic use; D008078:Cholesterol, LDL / Q000235:genetics; D000069438:Ezetimibe; D005799:Genes, Dominant; D006579:Heterozygote; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006938:Hyperlipoproteinemia Type II / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics; D009154:Mutation; D011973:Receptors, LDL / Q000235:genetics
chemical_list: D000924:Anticholesteremic Agents; D001384:Azetidines; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011973:Receptors, LDL; D000069438:Ezetimibe