title: Recurrent bilateral gingival peripheral calcifying epithelial odontogenic tumor (Pindborg tumor): a case report.
abstract: Calcifying epithelial odontogenic tumor (CEOT) is an extremely rare, benign neoplasm, accounting for approximately 1% of all odontogenic tumors. Peripheral CEOTs commonly resemble oral hyperplastic or reactive lesions and are histologically similar to their intraosseous counterparts. We report an unusual case of multifocal peripheral CEOT. A 40-year-old female presented with bilateral soft, painful, erythematous, gingival swellings localized in premolar areas of the mandibular gingiva. The presumptive diagnosis was bilateral pyogenic granuloma. The masses were surgically excised under local anesthesia without bone curettage and both recurred 12 months later. Morphologic features, and histochemical and immunohistochemical tests revealed bilateral peripheral calcifying odontogenic epithelial tumor. There is no clinical or radiographic evidence of recurrence 3.5 years after excision. This multifocal phenomenon has been reported previously only for intraosseous CEOT. Gingival masses must be carefully evaluated for clinical and histologic evidence of neoplasia.
authors.affiliation: Department of Pathology and Oral Diagnosis, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ac_abrahao@yahoo.com.br
authors.forename: Aline Corrêa
authors.initials: AC
authors.lastname: Abrahão
authors.forename: Danielle Resende
authors.initials: DR
authors.lastname: Camisasca
authors.forename: Beatriz R M Venturi
authors.initials: BR
authors.lastname: Bonelli
authors.forename: Márcia Grillo
authors.initials: MG
authors.lastname: Cabral
authors.forename: Simone Q C
authors.initials: SQ
authors.lastname: Lourenço
authors.forename: Sandra R
authors.initials: SR
authors.lastname: Torres
authors.forename: Décio Santos
authors.initials: DS
authors.lastname: Pinto
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005882:Gingival Diseases / Q000175:diagnosis; D005887:Gingival Neoplasms / Q000175:diagnosis*; D017789:Granuloma, Pyogenic / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D009808:Odontogenic Tumors / Q000175:diagnosis*