title: Early changes in pulmonary functions after mitral valve replacement.
abstract: BACKGROUND
  This study evaluates changes in pulmonary functions before and after mitral valve replacement (MVR).
  
  
  METHODS
  Twenty-five patients with rheumatic mitral lesions who had undergone MVR were divided into three groups, based on New York Heart Association (NYHA) class. They were evaluated for changes in pulmonary functions, preoperatively and postoperatively at 1 week, 1 month and 3 months to find any improvements after MVR.
  
  
  RESULTS
  Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow rates were universally found to be decreased preoperatively. Total lung capacity (TLC) and diffusion capacity (DLCO) were significantly reduced preoperatively in NYHA Class III and IV. The pulmonary functions further declined at 1 week after surgery. Except for FVC in NYHA Class IV (32.3% improvement, P < 0.05), the changes were statistically insignificant.
  
  
  CONCLUSIONS
  Pulmonary functions deteriorate immediately after surgery and then recover gradually over a period of 3 months. However, they remain below the predicted values.
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Saxena
authors.forename: Suvitesh
authors.initials: S
authors.lastname: Luthra
authors.forename: Rajinder Singh
authors.initials: RS
authors.lastname: Dhaliwal
authors.forename: Surinder Singh
authors.initials: SS
authors.lastname: Rana
authors.forename: Digambar
authors.initials: D
authors.lastname: Behera