Diversity of the bla(SHV) genes.
We investigated the diversity of nucleotide sequences of 297 SHV-encoding genes, based on nucleotide synonymous mutations and the presence or absence of the nonsynonymous mutation T92A. The analysis of this diversity allowed us to develop and propose a classification to differentiate the nucleotide sequence variants of the bla(SHV) genes.
Mendonça
Nuno
N
Antibiotic Resistance Unit, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, 1649-016 Lisbon, Portugal.
Nicolas-Chanoine
Marie-Hélène
MH
Caniça
Manuela
M
D019943:Amino Acid Substitution / Q000235:genetics; D001426:Bacterial Proteins / Q000145:classification / Q000235:genetics*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics*; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics; D005796:Genes; D014644:Genetic Variation; D020125:Mutation, Missense; D017354:Point Mutation; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000145:classification / Q000235:genetics*
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D001618:beta-Lactamases