title: Synthesis of exciton-controlled fluorescent probes for RNA imaging.
abstract: The excitonic interaction of thiazole orange dyes is known to suppress fluorescence emission. We have developed hybridization-sensitive fluorescent probes utilizing the excitonic interaction of two thiazole orange dyes connected to the probes. Here, we report nuclease-resistant hybridization-sensitive probes for long-term intracellular RNA imaging.
authors.affiliation: RIKEN Advanced Science Institute, Wako, Saitama 351-0198, Japan.
authors.forename: Shuji
authors.initials: S
authors.lastname: Ikeda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kubota
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yanagisawa
authors.forename: Mizue
authors.initials: M
authors.lastname: Yuki
authors.forename: Akimitsu
authors.initials: A
authors.lastname: Okamoto
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D012313:RNA / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012313:RNA