[Dietary intake and dyslipidemia arising from combination antiretroviral therapy for HIV infection: a systematic review].
To review and synthesize the available scientific evidence on the relationship between dietary intake and dyslipidemias in HIV-infected patients in combination antiretroviral therapy (ART). A systematic review of literature was carried out. Original and published studies were investigated and two categories of dietary exposure were considered: energy and nutrient intake, and consumption of a test diet. A narrative review of included studies was conducted. The findings were summarized according to category of metabolic outcomes (effect on total cholesterol and LDL-c, effect on HDL-c and effect on triglycerides). Twenty original studies were included in this review, being 13 clinical trials and 7 observational studies. Omega-3 fatty acid supplementation led to a significant decrease in triglycerides. There was very little evidence on the effectiveness of dietary interventions for the prevention and control of dyslipidemias in HIV-infected patients receiving ART.
Almeida
Luara Bellinghausen
LB
Faculdade de Saúde Pública da Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil.
Giudici
Kelly Virecoulon
KV
Jaime
Patricia Constante
PC
D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D002986:Clinical Trials as Topic; D004032:Diet; D050171:Dyslipidemias / Q000097:blood / Q000139:chemically induced / Q000517:prevention & control*; D002149:Energy Intake; D019317:Evidence-Based Medicine; D005247:Feeding Behavior; D015658:HIV Infections / Q000178:diet therapy / Q000188:drug therapy*; D006801:Humans; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides