Actinic keratosis: precancer, squamous cell carcinoma, or marker of field cancerization?
The early detection, recognition, and progression of the actinic keratosis (AK) and its relationship with squamous cell carcinoma have long been an area of debate. Recent advancements in medicine have examined the role of field cancerization in a variety of tumors. The role of AK as a marker for field cancerization will be here discussed.
Deltondo
J A
JA
Departments of Pathology and Dermatology, Penn State-Milton S. Hershey Medical Center, Hershey, PA, USA.
Helm
K F
KF
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D055623:Keratosis, Actinic / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*