title: Synthesis of deuterated benzyladenine and its application as a surrogate.
abstract: Palladium on carbon-ethylenediamine complex [Pd/C(en)] catalyzed deuteration of N(6)-benzyladenine-d(5), which is a plant growth regulator, to introduce 5 deuterium atoms, while use of Pd/C as a catalyst led to a complete removal of N(6)-benzyl group. The corresponding deuterated N(6)-benzyladenine was successfully used as a surrogate compound for the quantitative analysis of residual benzyladenine in crops using LC/MS/MS.
authors.affiliation: Department of Organic and Medicinal Chemistry, Laboratory of Organic Chemistry, Gifu Pharmaceutical University, Gifu 502-8585, Japan.
authors.forename: Nkaelang
authors.initials: N
authors.lastname: Modutlwa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tada
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Sugahara
authors.forename: Koichi
authors.initials: K
authors.lastname: Shiraki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hara
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Deyashiki
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ando
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Maegawa
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Monguchi
authors.forename: Hironao
authors.initials: H
authors.lastname: Sajiki
mesh_terms: D001593:Benzyl Compounds; D002853:Chromatography, Liquid; D003903:Deuterium; D007701:Kinetin / Q000032:analysis* / Q000138:chemical synthesis* / Q000737:chemistry; D010937:Plant Growth Regulators / Q000032:analysis* / Q000138:chemical synthesis* / Q000737:chemistry; D011687:Purines; D053719:Tandem Mass Spectrometry
chemical_list: D001593:Benzyl Compounds; D010937:Plant Growth Regulators; D011687:Purines; D003903:Deuterium; C480551:benzylaminopurine; D007701:Kinetin