title: Findings and risk factors of early mortality of endoscopic retrograde cholangiopancreatography in different cohorts of elderly patients.
abstract: OBJECTIVE
  To analyze experience of endoscopic retrograde cholangiopancreatography (ERCP) in patients with of different age cohorts and discuss the risk factors of early mortality after ERCP.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Tertiary care medical center.
  
  
  METHODS
  Two hundred sixty-four patients with pancreatobiliary diseases divided into cohorts according to decades as young-old (YO, 65-74, n=143), old-old (OO, 75-84, n=88), and very-old (VO, >or=85, n=33).
  
  
  METHODS
  The indications, results, and complications of ERCP in these three groups were demonstrated and compared.
  
  
  RESULTS
  Three hundred three ERCP procedures were performed. The leading indication for ERCP was common bile duct (CBD) obstruction or dilation. Diabetes mellitus was significantly more prevalent in the YO group (39.2%) than in the other two groups (OO, 15.9%; VO, 24.2%; P=.001). The most common finding of ERCP was CBD dilatation. There was no difference in incidence of malignant diseases between the three groups. Acute pancreatitis was the most frequently identified post-ERCP complication. There was no significant difference in early mortality between the three cohorts. Patients with malignancy had higher early mortality than those with benign disease (71.4% vs 11.2%; P=.001).
  
  
  CONCLUSIONS
  The findings and incidences of complication of ERCP in different elderly cohorts were similar. Underlying malignancy seemed to bear some relation to early mortality after the ERCP procedure.
authors.affiliation: Department of Internal Medicine, Division of Gastroenterology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Kuang-Chun
authors.initials: KC
authors.lastname: Hu
authors.forename: Wen-Hsiung
authors.initials: WH
authors.lastname: Chang
authors.forename: Cheng-Hsin
authors.initials: CH
authors.lastname: Chu
authors.forename: Horng-Yuan
authors.initials: HY
authors.lastname: Wang
authors.forename: Shee-Chan
authors.initials: SC
authors.lastname: Lin
authors.forename: Tsang-En
authors.initials: TE
authors.lastname: Wang
authors.forename: Shou-Chuan
authors.initials: SC
authors.lastname: Shih
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects* / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors