Plasmodium berghei ookinetes glide and release Pbs25 and circumsporozoite thrombospondin-related protein on solid surface substrata.
Plasmodium spp. development within mosquito vectors includes invasive ookinete and sporozoites stages, which display gliding movements during invasion of the midgut and salivary glands, respectively. Sporozoite gliding has been well documented, and several proteins released during sporozoite's locomotion have been described. However, proteins on the ookinete gliding trails are poorly described. In the present study, we documented that 2 proteins, Pbs25 and circumsporozoite thrombospondin-related protein (CTRP), are released during Plasmodium berghei ookinete gliding on a solid surface substrate.
Lecona
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AN
Centro de Investigaciones Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Ave. Universidad No. 655, Col. Santa María Ahuacatitlán, Cuernavaca, Morelos, México.
Rodríguez
M H
MH
Argotte
R S
RS
Alvarado
A
A
Rodríguez
M C
MC
D000953:Antigens, Protozoan / Q000378:metabolism; D000954:Antigens, Surface / Q000378:metabolism; D019084:Fluorescent Antibody Technique, Indirect; D017780:Malaria Vaccines / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D016253:Microscopy, Immunoelectron; D009068:Movement / Q000502:physiology; D010962:Plasmodium berghei / Q000502:physiology* / Q000648:ultrastructure; D015800:Protozoan Proteins / Q000378:metabolism*; D019699:Thrombospondins / Q000378:metabolism
D000953:Antigens, Protozoan; D000954:Antigens, Surface; D017780:Malaria Vaccines; D008565:Membrane Proteins; D015800:Protozoan Proteins; C121473:Pvs25 protein, P vivax; D019699:Thrombospondins; C041595:circumsporozoite protein, Protozoan; C069428:thrombospondin-related adhesive protein, protozoan