Mechanisms of deficit of visuospatial attention shift in children with developmental coordination disorder: a neurophysiological measure of the endogenous Posner paradigm.
The purpose of this study was to investigate and compare the mechanisms of brain activity, as revealed by a combination of the visuospatial attention shifting paradigm and event-related potentials (ERP) in children with developmental coordination disorder (DCD) and typically developing children. Twenty-eight DCD children and 26 typically developing children were recorded with regard to their behavioral performance and ERP measures during a variant of the endogenous Posner paradigm, in which they should react to visual targets preceded by spatial cues or presented uncued. Children with DCD showed longer reaction time and a deficit in inhibitory response capacity when compared to typically developing children. The electrophysiological characteristics also showed distinct modulatory effects upon attentional orienting, anticipatory mechanisms, and cognitive-to-motor transfer in children with DCD: longer cue-P3 and target-N1 latency, smaller target-P3 amplitude, an elongated interval between N2 and the motor response (N2-RT), and small areas on contingent negative variation (CNV). The combined analysis of behavioral performance and ERP data suggested that children with DCD had deficits of slower target identification (N1), less ability in interhemispheric (P3) and cognitive-to-motor transfer speed (N2-RT), as well as a less mature anticipatory and executive process (CNV).
Tsai
Chia-Liang
CL
Lab of Cognitive Neurophysiology, Institute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan City, Taiwan. andytsai@mail.ncku.edu.tw
Pan
Chien-Yu
CY
Cherng
Rong-Ju
RJ
Hsu
Ya-Wen
YW
Chiu
Hsing-Hui
HH
D000704:Analysis of Variance; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D002648:Child; D002657:Child Development / Q000502:physiology; D003265:Contingent Negative Variation / Q000502:physiology; D003463:Cues; D004569:Electroencephalography; D005074:Evoked Potentials, Visual / Q000502:physiology; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D019957:Motor Skills Disorders / Q000503:physiopathology*; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology; D018579:Patient Selection; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013028:Space Perception / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*