Flow injection and sequential injection on-line pre-column derivatization for liquid chromatography.
Approaches of on-line pre-column derivatization with flow injection (FI) and sequential injection (SI) for liquid chromatography (LC) are reviewed. Considerations in interfacing FI/SI to LC is discussed. Employing such on-line derivatization pre-column pretreatment approaches, applications to organic species (biomedical, food, pharmaceutical, environmental, and other types of samples) as well as metal ions are presented. Further developments in the approaches are recommended.
Burakham
Rodjana
R
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Grudpan
Kate
K