Effects of acupuncture at Neiguan (PC 6) on electroencephalogram.
The aim of this study was to investigate if there were any effects on the electroencephalogram (EEG) of human brain by the manual stimulation of Neiguan (PC 6) acupuncture site. In this paper, two groups of six healthy male volunteers of ages 27.6 +/- 14.2 (mean +/- SD) and 28.5 +/- 13.0 (mean +/- SD) and no neurological disease participated in this study. A digital storage of 12-channel EEG recorder was used and spectral analyses of the data set of 18 trials were obtained before, during, and after sham/ manual acupuncture. To minimize artefacts, all data were collected with the subjects alert but eyes closed. No significant changes (P > 0.05) were obtained for the sham acupuncture group. As for the manual acupuncture group, the needle was inserted perpendicularly into the PC 6 acupuncture site and manually stimulated about 15 to 30 seconds to achieve De Qi sensation. Needles were left in place for 30 min and then removed. Analysis of the EEG data due to acupuncture was compared to the baseline data and changes were obtained. First, all trials had an increase in the amplitude and power of the alpha band during manual acupuncture (P < 0.05) when compared with the baseline data. Secondly, in the mean time, the frequency peaks in alpha band of 12-channels were all synchronized with much smaller standard deviation (P < 0.01). Thirdly, the manual acupuncture effects of higher power and synchronized frequencies persisted for at least 10 minutes after the experiment (P < 0.05) and did not disappear immediately for all 18 experiments. Finally, we hypothesized that the higher power and synchronized rhythms in brain oscillations may have to do with autonomic nervous system.
Chang
Shyang
S
Department of Electrical Engineering, National Tsing Hua University, Hsinchu 300, Taiwan, ROC. shyang@ee.nthu.edu.tw
Chang
Zhe-Gung
ZG
Li
Shiun-Jeng
SJ
Chiang
Meng-Ju
MJ
Ma
Chia-Mei
CM
Cheng
Hsiu-Yao
HY
Hsieh
Sheng-Hwu
SH
D015669:Acupuncture Points; D000293:Adolescent; D000328:Adult; D000513:Alpha Rhythm; D016477:Artifacts; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D006801:Humans; D008297:Male; D055815:Young Adult