First case of extensive spinal cord infection with Aspergillus nidulans in a child with chronic granulomatous disease.
Chronic granulomatous disease (CGD) is characterized by a defect in phagocytic cells that lead to recurrent bacterial and fungal infections. The etiology of most common fungal infections in CGD are Aspergillus species. Aspergillus nidulans is one of several species of Aspergillus with low pathogenicity. However, it was reported to cause fatal invasive Aspergillosis in patients with CGD. Here we report the first cured invasive Aspergillus nidulans infection with extensive involvement of the spinal cord in a five-year-old child with CGD.
Bukhari
Elham
E
Department of Paediatrics, College of Medicine and King Khalid University Hospital, Riyadh, Saudi Arabia. ebukhari@yahoo.com
Alrabiaah
Abdulkarim
A
D001233:Aspergillus nidulans / Q000302:isolation & purification*; D002675:Child, Preschool; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D008297:Male; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D011859:Radiography; D013116:Spinal Cord / Q000000981:diagnostic imaging / Q000382:microbiology*