Findings and risk factors of early mortality of endoscopic retrograde cholangiopancreatography in different cohorts of elderly patients.
OBJECTIVE
To analyze experience of endoscopic retrograde cholangiopancreatography (ERCP) in patients with of different age cohorts and discuss the risk factors of early mortality after ERCP.


METHODS
Retrospective study.


METHODS
Tertiary care medical center.


METHODS
Two hundred sixty-four patients with pancreatobiliary diseases divided into cohorts according to decades as young-old (YO, 65-74, n=143), old-old (OO, 75-84, n=88), and very-old (VO, >or=85, n=33).


METHODS
The indications, results, and complications of ERCP in these three groups were demonstrated and compared.


RESULTS
Three hundred three ERCP procedures were performed. The leading indication for ERCP was common bile duct (CBD) obstruction or dilation. Diabetes mellitus was significantly more prevalent in the YO group (39.2%) than in the other two groups (OO, 15.9%; VO, 24.2%; P=.001). The most common finding of ERCP was CBD dilatation. There was no difference in incidence of malignant diseases between the three groups. Acute pancreatitis was the most frequently identified post-ERCP complication. There was no significant difference in early mortality between the three cohorts. Patients with malignancy had higher early mortality than those with benign disease (71.4% vs 11.2%; P=.001).


CONCLUSIONS
The findings and incidences of complication of ERCP in different elderly cohorts were similar. Underlying malignancy seemed to bear some relation to early mortality after the ERCP procedure.
Hu
Kuang-Chun
KC
Department of Internal Medicine, Division of Gastroenterology, Mackay Memorial Hospital, Taipei, Taiwan.
Chang
Wen-Hsiung
WH
Chu
Cheng-Hsin
CH
Wang
Horng-Yuan
HY
Lin
Shee-Chan
SC
Wang
Tsang-En
TE
Shih
Shou-Chuan
SC
D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects* / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors