title: A divergent strategy to the withasomnines.
abstract: A concise synthesis of three members of the withasomnine family of natural products is reported. The synthesis features a regioselective sydnone-alkynylboronate cycloaddition followed by Suzuki cross coupling and silyl group removal, and marks the first divergent approach to this family of pyrazole based natural products.
authors.affiliation: Department of Chemistry, University of Sheffield, Sheffield, UK S3 7HF.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Foster
authors.forename: Jianhui
authors.initials: J
authors.lastname: Huang
authors.forename: Jérôme F
authors.initials: JF
authors.lastname: Vivat
authors.forename: Duncan L
authors.initials: DL
authors.lastname: Browne
authors.forename: Joseph P A
authors.initials: JP
authors.lastname: Harrity
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry*; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity; D013558:Sydnones / Q000737:chemistry
chemical_list: D000470:Alkaloids; D001688:Biological Products; D011720:Pyrazoles; D013558:Sydnones