A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity.
ESI mass spectrometry was used to assess the ability of metal complexes to inhibit binding of a transcription factor to a DNA molecule containing its recognition sequence.
Talib
Jihan
J
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.
Beck
Jennifer L
JL
Urathamakul
Thitima
T
Nguyen
Cuong D
CD
Aldrich-Wright
Janice R
JR
Mackay
Joel P
JP
Ralph
Stephen F
SF
D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D009944:Organoplatinum Compounds / Q000737:chemistry*; D011485:Protein Binding; D011518:Proto-Oncogene Proteins / Q000737:chemistry* / Q000378:metabolism; D012428:Ruthenium / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D015534:Trans-Activators / Q000737:chemistry* / Q000378:metabolism; D000099232:Proto-Oncogene Protein Spi-1
D004247:DNA; D008670:Metals; D009942:Organometallic Compounds; D009944:Organoplatinum Compounds; D011518:Proto-Oncogene Proteins; D012428:Ruthenium; D015534:Trans-Activators; D000099232:Proto-Oncogene Protein Spi-1