title: Predictors of health status in nondepressed and nondemented individuals with Parkinson's disease.
abstract: Recent studies have shown that self-perceived health status (HS) in Parkinson's disease (PD) is associated with motor, cognitive, or mood symptoms, with the greatest association typically occurring with mood. The purpose of this study was to determine if these associations are present in nondepressed and nondemented individuals with PD by using sensitive neuropsychological measures and statistically derived factors from mood and motor scales. The best predictors of poor HS in PD participants (N = 32) without dementia or depression were mood symptoms, specific to self-reported cognitive impairment and anxiety. Bivariate correlations between HS and number of correct categories on the Wisconsin Card Sorting Test and the gait-balance factor from the Unified Parkinson's Disease Rating Scale Part III were also significant or approached significance. These findings suggest that specific mood and cognitive symptoms continue to be important factors in HS in those individuals who lack clinical levels of depression or dementia.
authors.affiliation: Department of Psychiatry, Univeristy of California of San Diego, San Diego, CA, USA.
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Schiehser
authors.forename: S Duke
authors.initials: SD
authors.lastname: Han
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lessig
authors.forename: David D
authors.initials: DD
authors.lastname: Song
authors.forename: Vanessa
authors.initials: V
authors.lastname: Zizak
authors.forename: J Vincent
authors.initials: JV
authors.lastname: Filoteo
mesh_terms: D000339:Affect; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000150:complications / Q000175:diagnosis; D003704:Dementia / Q000150:complications; D003863:Depression / Q000150:complications / Q000523:psychology; D004185:Disability Evaluation; D005260:Female; D005684:Gait; D020233:Gait Disorders, Neurologic / Q000150:complications; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D011597:Psychomotor Performance; D011788:Quality of Life / Q000523:psychology*; D012044:Regression Analysis; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires