title: Chromoblastomycosis in Sarawak, East malaysian Borneo.
abstract: A retrospective study was conducted to determine the clinical characteristics and treatment outcomes of 11 new patients with a histological diagnosis of chromoblastomycosis at Sarawak General Hospital, Malaysia, between 1996 and 2008. The majority (81.8%) were males, and the median age at presentation was 40 years. Over half the patients were farmers. All the patients had irregular verrucous lesions, mostly on the lower limbs (90.9%), and had initially been misdiagnosed. The mean duration of the lesions was 13.8 years. Oral terbinafine and itraconazole were administered to all the patients; clinical cure was seen in 54.5%, and partial response in 18.2%. Concomitant electrocautery and cryotherapy were only effective for small lesions.
authors.affiliation: Department of Dermatology, Sarawak General Hospital, 93586 Kuching, Sarawak, Malaysia. woodzlamp@yahoo.com
authors.forename: Felix Boon Bin
authors.initials: FB
authors.lastname: Yap
mesh_terms: D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D001893:Borneo; D002862:Chromoblastomycosis / Q000473:pathology / Q000628:therapy*; D017679:Cryotherapy; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use; D012189:Retrospective Studies; D000077291:Terbinafine; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D017964:Itraconazole; D000077291:Terbinafine