title: Cytological comparison of fine-needle aspirates of liver and spleen of normal dogs and of dogs with cutaneous mast cell tumours and an ultrasonographically normal appearing liver and spleen.
abstract: Staging of dogs with cutaneous mast cell tumours (MCTs) is an important diagnostic step. Aspiration of the liver and the spleen is often part of routine staging. This study cytologically compared mast cell numbers in fine-needle aspirates of liver and spleen of clinically normal unaffected dogs with those of dogs with cutaneous MCT and an ultrasonographically normal appearing liver and spleen. The unaffected dogs (n = 32) were selected from humane society dogs, and the affected dogs (n = 51) were selected from hospital cases. There were no statistically significant differences in each of the parameters evaluated for the liver aspirates. For splenic aspirates, affected dogs showed significantly more mast cells per cluster (P = 0.04) and more isolated mast cells per slide (P = 0.03) compared with unaffected dogs. However, no clinically important difference existed between the unaffected and affected dogs; thus, routine aspiration of an ultrasonographically normal appearing liver and spleen of dogs with cutaneous MCT does not appear to be a clinically useful staging tool.
authors.affiliation: Department of Medicine, Animal Medical Center, New York, NY 10021, USA. kfinora@hotmail.com
authors.forename: K
authors.initials: K
authors.lastname: Finora
authors.forename: N F
authors.initials: NF
authors.lastname: Leibman
authors.forename: M J
authors.initials: MJ
authors.lastname: Fettman
authors.forename: B E
authors.initials: BE
authors.lastname: Powers
authors.forename: T A
authors.initials: TA
authors.lastname: Hackett
authors.forename: S J
authors.initials: SJ
authors.lastname: Withrow