Preparation and bioapplication of high-quality, water-soluble, biocompatible, and near-infrared-emitting CdSeTe alloyed quantum dots.
A facile method is developed for the preparation of high-quality, water-soluble, and near-infrared (NIR)-emitting CdSeTe alloyed quantum dots (AQdots) with L-cysteine as the capping agent. By changing the size and the composition of AQdots the photoluminescent quantum yield (QY) can reach as high as 53% and the emission color can be tuned between visible and NIR regions (580-814 nm). Furthermore, the prepared NIR-emitting AQdots have been successfully applied for HL-60 cell imaging and glucose and cholesterol assay, which demonstrates the great potential of the AQdots for biological applications.
Liang
Guo-Xi
GX
Key Laboratory of Analytical Chemistry for Life Science (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, People's Republic of China.
Gu
Miao-Miao
MM
Zhang
Jian-Rong
JR
Zhu
Jun-Jie
JJ
D000497:Alloys / Q000138:chemical synthesis / Q000737:chemistry*; D002104:Cadmium / Q000737:chemistry*; D003952:Diagnostic Imaging / Q000379:methods*; D018922:HL-60 Cells; D006801:Humans; D036103:Nanotechnology / Q000379:methods*; D045663:Quantum Dots; D012643:Selenium / Q000737:chemistry*; D013691:Tellurium / Q000737:chemistry*
D000497:Alloys; D002104:Cadmium; D012643:Selenium; D013691:Tellurium