title: Hemiterpene glucosides and other constituents from Spiraea canescens.
abstract: Five glycosides, 2-(trans-cinnamoyloxy-methyl)-1-butene-4-O-beta-D-glucopyranoside (1), 4-(6'-O-trans-cinnamoyl)-(2-hydroxymethyl-4-hydroxy-butenyl-beta-D-glucopyranoside (2), 6''-O-trans-p-coumaroyl-(4-hydroxybenzoyl)-beta-D-glucopyranoside (3), 6'-O-(4-methoxy-trans-cinnamoyl) alpha/beta-D-glucopyranose (4) 6'-O-(4''-methoxy-trans-cinnamoyl)-kaempferol-3-beta-D-glucopyranoside (7) along with six known compounds, (+)-isolariciresinol 3a-O-beta-D-glucopyranoside (8) (+)-lyoniresinol 3a-O-beta-D-glucopyranoside (9), apigenin 7-O-beta-D-glucopyranoside (10), quercetin 3-O-beta-D-glucopyranoside (11), 6'-O-cinnamoyl-alpha/beta-D-glucopyranose (6) 6'-O-p-coumaroyl-alpha/beta-D-glucopyranose (5) were isolated from the whole plant of Spiraea canescens. Some of these compounds showed potent radical scavenging activity in relevant non-physiological assays. Their structures were determined by NMR spectroscopic and CID mass spectrometric techniques.
authors.affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. hej@cyber.net.pk
authors.forename: M Iqbal
authors.initials: MI
authors.lastname: Choudhary
authors.forename: Nadra
authors.initials: N
authors.lastname: Naheed
authors.forename: Ahmed
authors.initials: A
authors.lastname: Abbaskhan
authors.forename: Sajjad
authors.initials: S
authors.lastname: Ali
authors.lastname: Atta-ur-Rahman
mesh_terms: D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D002934:Cinnamates / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D009005:Monosaccharides / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D031992:Spiraea / Q000737:chemistry*; D013729:Terpenes / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: C546008:2-(trans-cinnamoyloxy-methyl)-1-butene-4-O-beta-D-glucopyranoside; D000975:Antioxidants; D002934:Cinnamates; D006027:Glycosides; D009005:Monosaccharides; D010936:Plant Extracts; D013729:Terpenes