Bilateral epibulbar xanthomas--a case report.
OBJECTIVE
To report bilateral epibulbar xanthomatous lesions in an adult with a normal serum lipid profile and no cutaneous or systemic features of a histiocytic disease.


METHODS
Clinicopathologic report.


RESULTS
A 44-year-old man presented with gradually enlarging yellow epibulbar masses in both eyes. The lesions had recurred after excisions performed 2 years previously. Systemic evaluation was normal. Excisional biopsies were performed, and histological examination revealed numerous foamy histiocytes with scattered Touton giant cells and lymphocytes. No recurrence was observed after 1 year of follow-up.


CONCLUSIONS
Xanthomatous epibulbar lesions are exceedingly rare and may occur as an isolated finding. Evaluation should be directed toward detecting underlying non-Langerhans cell histiocytic diseases and disorders of lipid metabolism. Recurrent lesions may be successfully treated by surgical excision.
Satchi
Khami
K
Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Loughnan
Michael S
MS
McKelvie
Penelope A
PA
McNab
Alan A
AA
D000328:Adult; D003229:Conjunctival Diseases / Q000473:pathology* / Q000601:surgery; D005128:Eye Diseases / Q000473:pathology* / Q000601:surgery; D007839:Functional Laterality; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D014792:Visual Acuity; D014973:Xanthomatosis / Q000473:pathology* / Q000601:surgery