title: Dividing the goods: co-ordination of chromosome biorientation and mitotic checkpoint signalling by mitotic kinases.
abstract: Error-free chromosome segregation during cell division relies on chromosome biorientation and mitotic checkpoint activity. A group of unrelated kinases controls various aspects of both processes. The present short review outlines our current understanding of the roles of these kinases in maintaining chromosomal stability.
authors.affiliation: Department of Physiological Chemistry and Cancer Genomics Centre, UMC Utrecht, Utrecht, The Netherlands. g.j.p.l.kops@umcutrecht.nl
authors.forename: Geert J P L
authors.initials: GJ
authors.lastname: Kops
mesh_terms: D018797:Cell Cycle Proteins / Q000378:metabolism*; D045584:Chromosome Positioning; D020090:Chromosome Segregation; D006801:Humans; D018386:Kinetochores / Q000378:metabolism; D008938:Mitosis / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D008941:Spindle Apparatus / Q000378:metabolism*
chemical_list: D018797:Cell Cycle Proteins; D017346:Protein Serine-Threonine Kinases