title: Cell phenotyping in saliva of individuals under psychological stress.
abstract: Total leukocytes, NK cells, B and T lymphocytes present in the saliva of medical students with or without stress were quantified by flow cytometry in 10,000 events. The symptoms of psychological stress were monitored with Lipp's Inventory of Stress Symptoms for Adults (ISSL). No significant differences were observed in the number of cells phenotyped in students with and those without psychological stress. However, a negative correlation was observed between the number of NK cells and T lymphocytes in students with stress (r=-0.8173; p=0.0058), suggesting that innate immunity is predominant in the adaptation phase.
authors.affiliation: Laboratório de Imunologia, Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal do Amazonas, Manaus Amazonas, Brazil. mcsantos@ufam.edu.br
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Dos-Santos
authors.forename: Nathália
authors.initials: N
authors.lastname: Matos-Gomes
authors.forename: Fabiano Hiromichi
authors.initials: FH
authors.lastname: Makimoto
authors.forename: Marilise
authors.initials: M
authors.lastname: Katsurayama
authors.forename: Linda Luciana Oliveira
authors.initials: LL
authors.lastname: Santana
authors.forename: Maria Alice d'Avila
authors.initials: MA
authors.lastname: Becker
authors.forename: Edijane
authors.initials: E
authors.lastname: Paredes-Garcia
authors.forename: Alvaro L
authors.initials: AL
authors.lastname: Bertho
mesh_terms: D000222:Adaptation, Physiological / Q000276:immunology*; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D003430:Cross-Sectional Studies; D005434:Flow Cytometry; D006801:Humans; D007113:Immunity, Innate; D007694:Killer Cells, Natural / Q000276:immunology; D007962:Leukocytes / Q000276:immunology; D008297:Male; D010641:Phenotype; D012463:Saliva / Q000166:cytology / Q000276:immunology*; D013315:Stress, Psychological / Q000276:immunology* / Q000523:psychology; D013337:Students, Medical / Q000523:psychology; D013601:T-Lymphocytes / Q000276:immunology; D055815:Young Adult