Performance of a new interference-resistant glucose meter.
OBJECTIVE
Glucose meters are widely used in self and hospital monitoring of blood glucose. We examined the analytical performance of a StatStrip glucose monitoring system.


METHODS
Linearity, % recovery and within-run imprecision were studied using glucose-spiked whole blood. A total of 120 heparinized samples were used in method comparison using a plasma hexokinase on the Dimension RxL MAX analyzer as the comparison method. Common interferences were tested on the StatStrip, Accu-Chek Advantage and the MediSense Optium glucose meters at low, middle and high glucose levels.


RESULTS
The StatStrip assay showed excellent linearity and recovery. The coefficient of variations for imprecision were <5%. This meter correlated well with the comparison method (y=0.994X+0.03; r=0.995, S(y/x)=0.05 mmol/L, bias=-0.01 mmol/L). Of the three meters tested, only the StatStrip showed interference <10% for all spiked levels of acetaminophen, ascorbic acid, maltose and hematocrit at three levels of glucose tested.


CONCLUSIONS
The StatStrip meter showed good performance and is suitable for point-of-care hospital glucose testing.
Vanavanan
Somlak
S
Faculty of Medicine, Division of Clinical Chemistry, Department of Pathology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Santanirand
Pitak
P
Chaichanajarernkul
Upsorn
U
Chittamma
Anchalee
A
Dubois
Jeffrey A
JA
Shirey
Terry
T
Heinz
Mark
M
D000082:Acetaminophen / Q000032:analysis; D001205:Ascorbic Acid / Q000032:analysis; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D001774:Blood Chemical Analysis / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D006801:Humans; D008320:Maltose / Q000032:analysis; D019095:Point-of-Care Systems; D011934:Reagent Strips; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D001786:Blood Glucose; D011934:Reagent Strips; D000082:Acetaminophen; D008320:Maltose; D001205:Ascorbic Acid