[Severe disseminated toxoplasmosis with atypical chorioretinitis. A case of primary infection].
The clinical diagnosis of ocular toxoplasmosis is based on clinical features and biological tests: polymerase chain reaction (PCR) and the determination of intraocular specific antibody secretion (Goldmann-Witmer coefficient) on aqueous humor. Older patients may have a higher prevalence of ocular involvement and more severe ocular disease during the acute phase of recently acquired systemic infection because of altered cell-mediated immunity. Moreover, the genotype of the infecting parasite (particularly involving neotropical Type I Toxoplasma gondii strain), appears to be an important determinant of disease severity.
Errera
M H
MH
Service d'Ophtalmologie, Hôpital Lariboisière, Assistance Publique Hôpitaux de Paris, Paris, France.
Chahed
S
S
Man
H
H
Garin
Y J F
YJ
Bergmann
J F
JF
Gaudric
A
A
Massin
P
P
D002825:Chorioretinitis / Q000000981:diagnostic imaging / Q000469:parasitology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012720:Severity of Illness Index; D014126:Toxoplasmosis, Ocular / Q000000981:diagnostic imaging