title: Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates: a randomized phase II, placebo-controlled trial.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakase
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Fujiyama
authors.forename: Nobuhide
authors.initials: N
authors.lastname: Oshitani
authors.forename: Toru
authors.initials: T
authors.lastname: Oga
authors.forename: Kimiko
authors.initials: K
authors.lastname: Nonomura
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Esaki
authors.forename: Toshinori
authors.initials: T
authors.lastname: Murayama
authors.forename: Satoshi
authors.initials: S
authors.lastname: Teramukai
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Chiba
authors.forename: Shuh
authors.initials: S
authors.lastname: Narumiya
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004311:Double-Blind Method; D004351:Drug Resistance; D005260:Female; D006537:Heptanoates / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D019804:Mesalamine / Q000627:therapeutic use*; D008875:Middle Aged; D010919:Placebos; D018078:Receptors, Prostaglandin E / Q000819:agonists*; D058309:Receptors, Prostaglandin E, EP4 Subtype; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D006537:Heptanoates; C487764:ONO4819; C545650:PTGER4 protein, human; D010919:Placebos; D018078:Receptors, Prostaglandin E; D058309:Receptors, Prostaglandin E, EP4 Subtype; D019804:Mesalamine