title: Disseminated histoplasmosis presenting as granulomatous epididymo-orchitis.
abstract: Genital involvement is an unusual manifestation of histoplasmosis. We report a case of histoplasmosis presenting as granulomatous epididymo-orchitis and review 4 cases reported in the literature. Diagnosis of this infection is suggested by a compatible clinical picture and results of specific serology or antigen testing, but confirmation ultimately requires analysis of pathologic specimens. Surgical drainage or resection of involved tissues and systemic antifungals typically result in resolution of infection and improved outcomes.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555, USA. ctichindelean@mhc.net
authors.forename: Carmen
authors.initials: C
authors.lastname: Tichindelean
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: East
authors.forename: Juan C
authors.initials: JC
authors.lastname: Sarria
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004823:Epididymitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009920:Orchitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents