Oxidative carboxylation of arylaldehydes with water by a sulfoxylalkyl-substituted N-heterocyclic carbene catalyst.
The N-Heterocyclic carbene-catalysed oxidative carboxylation of arylaldehydes with water successfully proceeded when a sulfoxylalkyl-substituted imidazolium salt was used as the catalyst. The reactions can be run in the absence of oxidant, and a variety of arylaldehydes having an electron-withdrawing group were converted to the corresponding carboxylic acids.
Yoshida
Masahiro
M
Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Sho-machi, Tokushima, Japan. yoshida@ph.tokushima-u.ac.jp
Katagiri
Yuki
Y
Zhu
Wen-Bin
WB
Shishido
Kozo
K
D000447:Aldehydes / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D007093:Imidazoles / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D010084:Oxidation-Reduction; D014867:Water / Q000737:chemistry*
D000447:Aldehydes; D002264:Carboxylic Acids; D007093:Imidazoles; D014867:Water; C030011:carbene; C029899:imidazole; D008697:Methane