Association of common carotid intimal medial thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus.
OBJECTIVE
To determine the association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus.


METHODS
This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart disease, hypertension and smoking was recorded. Body mass index, glycosylated haemoglobin (HbA1c), total cholesterol, triglyceride and high density (HDL) cholesterol were determined in all the patients. CCA-IMT determination was done by Carotid Doppler Ultrasonography.


RESULTS
There were 120 (60%) males and 80 females (40%). Ages ranged from 28 to 79, mean 59.5 +/- 9.07 years. IMT on right side ranged from 0.4 mm to 2.4 mm, mean 0.88 mm and on left side mean IMT was 0.93 mm, range 0.5 mm to 2.5 mm. Duration of DM and BMI were correlated with IMT on both the sides (p < .05), statistically inverse correlation was seen with HDL cholesterol (p < .05). No significant correlation was seen with other variables.


CONCLUSIONS
Duration of DM, BMI and HDL cholesterol were associated with CCA-IMT in patients with type 2 DM. No significant association was seen with other risk factors.
Butt
Mujeeb-ur-Rehman Abid
MU
Department of Medicine, Combined Military Hospital (CMH), Lahore.
Zakaria
Manzar
M
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D017536:Carotid Artery, Common / Q000473:pathology*; D008076:Cholesterol, HDL; D003324:Coronary Artery Disease / Q000453:epidemiology*; D003925:Diabetic Angiopathies / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D017539:Tunica Intima / Q000473:pathology; D017540:Tunica Media / Q000473:pathology
D008076:Cholesterol, HDL