title: A unique presentation of complex regional pain syndrome type I treated with a continuous sciatic peripheral nerve block and parenteral ketamine infusion: a case report.
abstract: OBJECTIVE
  To successfully treat a patient with complex regional pain syndrome, refractory to standard therapy, to enable a rapid and full return to professional duties.
  
  
  METHODS
  This case report describes the rapid resolution of an unusual presentation of complex regional pain syndrome type I after four days of treatment with a continuous sciatic peripheral nerve block and a concomitant parenteral ketamine infusion. The patient was initially diagnosed with complex regional pain syndrome (CRPS) I of the right lower extremity following an ankle inversion injury. Oral medication with naproxen and gabapentin, as well as desensitization therapy, failed to provide any relief of her symptoms. She was referred to the interventional pain management clinic. A lumbar sympathetic block failed to provide any relief. The patient was diagnosed with CRPS I and was admitted for treatment with a continuous peripheral nerve block and parenteral ketamine.
  
  
  CONCLUSIONS
  This case suggests therapeutic benefit from aggressive treatment of both the peripheral and central components of CRPS.
authors.affiliation: Walter Reed Army Medical Center-Army Regional Anesthesia & Pain Medicine, Washington, DC 20307, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Everett
authors.forename: Brian
authors.initials: B
authors.lastname: Mclean
authors.forename: Anthony
authors.initials: A
authors.lastname: Plunkett
authors.forename: Chester
authors.initials: C
authors.lastname: Buckenmaier
mesh_terms: D000293:Adolescent; D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000627:therapeutic use*; D016512:Ankle Injuries / Q000150:complications; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007649:Ketamine / Q000008:administration & dosage / Q000627:therapeutic use*; D009288:Naproxen / Q000627:therapeutic use; D009407:Nerve Block; D010147:Pain Measurement; D012019:Reflex Sympathetic Dystrophy / Q000175:diagnosis / Q000188:drug therapy*; D012584:Sciatic Nerve
chemical_list: D000778:Anesthetics, Dissociative; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen; D007649:Ketamine