title: A pilot respiratory health assessment of nail technicians: symptoms, lung function, and airway inflammation.
abstract: BACKGROUND
  Recent surveys suggest nail technicians, particularly artificial nail applicators, have increased respiratory symptoms and asthma risk.
  
  
  METHODS
  We examined lung function (n = 62) and a marker of airway inflammation, i.e., exhaled nitric oxide (ENO) (n = 43), in a subset of nail technician and control participants in a pilot health assessment.
  
  
  RESULTS
  Bivariate analysis of technicians demonstrated that job latency was inversely correlated with FEV1 percent predicted (FEV1PP) (r = -0.34, P = 0.03) and FVCPP (r = -0.32, P = 0.05). Acrylic gel contact hours were inversely correlated with FEV1PP (r = -0.38, P = 0.02) and FVCPP (r = -0.47, P = 0.003). Current smoking was inversely and significantly (P <or= 0.05) associated with ENO in bivariate analysis. Log 10 ENO levels were directly correlated with job latency (P = 0.012) and gel nail application (P = 0.026) in multivariable analyses.
  
  
  CONCLUSIONS
  These positive pilot respiratory test results warrant additional future investigation.
authors.affiliation: Biomonitoring and Health Assessment Branch (BHAB), Division of Applied Research and Technology (DART), National Institute for Occupational Safety and Health (NIOSH), Cincinnati, Ohio 45226-1998, USA. swr0@cdc.gov
authors.forename: Susan R
authors.initials: SR
authors.lastname: Reutman
authors.forename: Amy M
authors.initials: AM
authors.lastname: Rohs
authors.forename: John C
authors.initials: JC
authors.lastname: Clark
authors.forename: Belinda C
authors.initials: BC
authors.lastname: Johnson
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Sammons
authors.forename: Christine A
authors.initials: CA
authors.lastname: Toennis
authors.forename: Shirley A
authors.initials: SA
authors.lastname: Robertson
authors.forename: Barbara A
authors.initials: BA
authors.lastname: MacKenzie
authors.forename: James E
authors.initials: JE
authors.lastname: Lockey
mesh_terms: D000328:Adult; D001505:Beauty Culture; D001944:Breath Tests; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009262:Nails; D009569:Nitric Oxide / Q000032:analysis; D016272:Occupational Health; D010865:Pilot Projects; D013147:Spirometry; D055815:Young Adult
chemical_list: D009569:Nitric Oxide