title: Splenic abscess due to brucellosis.
abstract: Splenic abscess due to Brucella spp. is extremely rare. We report a case of a splenic abscess due to Brucella spp. in a 61-year-old male patient. Brucella slide and tube agglutination tests (Wright) were positive while blood culture and culture from splenic tissue yielded negative results. The abdominal ultrasonography revealed a hypoechoic intrasplenic mass 15x12 mm in diameter at the middle portion of the spleen. The splenic lesions disappeared after prolonged treatment for 7 months with a combination of doxycycline, and rifampicin, followed by TMP-SXT. Brucella spp. should be considered in the differential diagnosis of splenic abscess in countries where brucellosis is endemic. The results of this case and literature review shows that a conservative approach using optimum antibiotics alone without surgical intervention can be successful in the treatment of patients with splenic brucellosis.
authors.affiliation: Infectious Disease Department, Ankara Oncology Hospital, Ankara, Turkey.
authors.forename: Kamuran
authors.initials: K
authors.lastname: Sayilir
authors.forename: Gülşen
authors.initials: G
authors.lastname: Iskender
authors.forename: Mustafa Cihat
authors.initials: MC
authors.lastname: Oğan
authors.forename: Filiz
authors.initials: F
authors.lastname: Erdil
mesh_terms: D018784:Abdominal Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D000372:Agglutination Tests; D000890:Anti-Infective Agents / Q000008:administration & dosage; D002006:Brucellosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004318:Doxycycline / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004791:Enzyme Inhibitors / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage; D013154:Spleen / Q000000981:diagnostic imaging / Q000187:drug effects; D013158:Splenic Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage; D014463:Ultrasonography
chemical_list: D000890:Anti-Infective Agents; D004791:Enzyme Inhibitors; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D004318:Doxycycline; D012293:Rifampin