title: Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora.
abstract: Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.
authors.affiliation: Pharmaceutical Research Centre, PCSIR Laboratories Complex, Karachi 75280, Pakistan.
authors.forename: Sadia
authors.initials: S
authors.lastname: Ferheen
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Lubna
authors.initials: L
authors.lastname: Iqbal
authors.forename: Muhammad
authors.initials: M
authors.lastname: Azam Rasool
authors.forename: Muhammad
authors.initials: M
authors.lastname: Irfan Ali
authors.forename: Rasool
authors.initials: R
authors.lastname: Bakhsh Tareen
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018514:Plant Structures / Q000737:chemistry; D014510:Urease / Q000037:antagonists & inhibitors
chemical_list: D000975:Antioxidants; D044950:Flavanones; D005960:Glucosides; D010936:Plant Extracts; C547298:galinsoside A; C547299:galinsoside B; D014510:Urease