title: Restless Legs Syndrome in shift workers: A cross sectional study on male assembly workers.
abstract: BACKGROUND
  Restless Legs Syndrome (RLS) is a common neurological movement disorder characterized by symptoms that follow a circadian pattern. Night and rotating shift work schedules exert adverse effects on functions of the human body by disturbing circadian rhythms, and they are known to cause sleep disturbances and insomnia. In this paper, we investigate the possible association between shift work and RLS.
  
  
  METHODS
  This cross sectional study was conducted in an automobile manufacturing factory in Tehran, Iran. A total of 780 male assembly workers were recruited in three groups, each with 260 workers: workers on a permanent morning shift (A) and two different rotating shift schedules (B and C) with morning, afternoon and night shifts. We used the international RLS study group criteria for diagnosis of RLS, and the severity scale for severity assessment in subjects with RLS. Self administered questionnaires were used to gather information on age, smoking, work history, medical condition, and existence and severity of RLS symptoms.
  
  
  RESULTS
  The prevalence of RLS was significantly higher in rotational shift workers (15%) than workers with permanent morning work schedule (8.5%). In workers suffering from RLS, we found greater mean values of age and work experience, higher percentages of drug consumption, smoking, and co-morbid illnesses compared with subjects who did not have RLS, although these differences were statistically significant only for age, work experience and drug consumption.
  
  
  CONCLUSIONS
  Rotational shift work acts as a risk or exacerbating factor for Restless Legs Syndrome.
authors.affiliation: Department of Occupational Medicine, Tehran University of Medical Sciences, Tehran, Iran. mfiroozeh@razi.tums.ac.ir.
authors.forename: Akbar
authors.initials: A
authors.lastname: Sharifian
authors.forename: Marjan
authors.initials: M
authors.lastname: Firoozeh
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Pouryaghoub
authors.forename: Mehran
authors.initials: M
authors.lastname: Shahryari
authors.forename: Mohsen
authors.initials: M
authors.lastname: Rahimi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Hesamian
authors.forename: Ali
authors.initials: A
authors.lastname: Fardi