title: Reply to Sergej V. Jargin: shock wave therapy of ischemic heart disease in the light of general pathology.
abstract: Low energy shock wave therapy has developed as a treatment standard or alternative therapy for a variety of orthopaedic and soft tissue diseases. In experimental studies it shows very promising results for the treatment of ischemic heart disease. Sergei V. Jargin reported on a device on the basis of a modified lithotripter that is currently used in Russia. He supposes the tissue regenerative effect to be an injury-and-repair process, which may end up in myocardial function loss. This hypothesis is contradictory to findings of numerous research groups. Low energy shock waves show in both clinical and experimental studies a safe and highly effective tissue regenerative potential that is mediated by various molecular and sub-molecular effects. Therefore low energy shock wave therapy is a promising treatment option for ischemic heart disease.
authors.affiliation: Dept. of Cardiothoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: johannes.holfeld@meduniwien.ac.at.
authors.forename: Johannes
authors.initials: J
authors.lastname: Holfeld
authors.affiliation: Dept. of Cardiothoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
authors.forename: Daniel
authors.initials: D
authors.lastname: Zimpfer
authors.affiliation: AUVA Trauma Center, Vienna, Austria.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schaden
authors.affiliation: Dept. of Cardiothoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Grimm
mesh_terms: D019220:High-Energy Shock Waves / Q000627:therapeutic use*; D006801:Humans; D017202:Myocardial Ischemia / Q000473:pathology* / Q000628:therapy*