title: Thyroid function and infertility in the dog: a survey in five breeds.
abstract: In our study, a clinical and reproductive examination was undertaken in 204 dogs of five different breeds. Thyroxine and thyroid-stimulating hormone plasma concentrations were assayed in order to assess the real incidence of hypothyroidism associated with reproductive disease. Among these animals, only two breeds were affected by hypothyroidism (4.5% of the Dogue de Bordeaux and 2.4% of the Leonbergers). Moreover, these animals did not suffer from any reproductive disease. Our study showed also that 70% of the male Dogue de Bordeaux were hypothyroxinemic compared with Great Danes, English Mastiff and Leonbergers whose male population was 100% normothyroidic. We found the same tendency in bitches. In our data, there was no difference in thyroxin plasma concentrations between normo- and hypofertile dogs, but our results were not statistically significant.
authors.affiliation: Reproduction Animale, Alfort Veterinary College, Paris, France. vsegalini@hotmail.fr
authors.forename: V
authors.initials: V
authors.lastname: Segalini
authors.forename: T
authors.initials: T
authors.lastname: Hericher
authors.forename: A
authors.initials: A
authors.lastname: Grellet
authors.forename: D
authors.initials: D
authors.lastname: Rosenberg
authors.forename: F
authors.initials: F
authors.lastname: Garnier
authors.forename: A
authors.initials: A
authors.lastname: Fontbonne
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000209:etiology* / Q000378:metabolism; D004285:Dogs; D005260:Female; D007037:Hypothyroidism / Q000150:complications / Q000662:veterinary*; D007246:Infertility / Q000150:complications / Q000662:veterinary*; D008297:Male; D011247:Pregnancy; D013960:Thyroid Function Tests / Q000662:veterinary; D013961:Thyroid Gland / Q000502:physiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D013974:Thyroxine