title: Polyomaviruses KI and WU in children with respiratory tract infection.
abstract: The polyomaviruses KI (KIPyV) and WU (WUPyV) have recently been discovered in specimens from patients with respiratory tract infections. To analyze the frequency and clinical impact in a cohort of pediatric patients in a German University Children's Hospital. Nasopharyngeal aspirates or bronchoalveolar lavage specimens of 229 children with acute respiratory tract infection were screened for KIPyV and WUPyV using polymerase chain reaction-based methods. KIPyV was detected in 2 (0.9%) and WUPyV in 1 (0.4%) patients, without co-infections with other respiratory viruses but with co-detection of CMV, EBV and HHV 6 in one immunocompromised patient. Only a very small proportion (1.3%) of positive samples for KIPyV and WUPyV was documented in this study; the clinical relevance of these viruses remains unclear and requires further evaluation.
authors.affiliation: Department of Pediatrics, University of Bonn, Bonn, Germany. a.mueller@ukb.uni-bonn.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Mueller
authors.forename: Arne
authors.initials: A
authors.lastname: Simon
authors.forename: Julia
authors.initials: J
authors.lastname: Gillen
authors.forename: Verena
authors.initials: V
authors.lastname: Schildgen
authors.forename: Ramona Liza
authors.initials: RL
authors.lastname: Tillmann
authors.forename: Karl
authors.initials: K
authors.lastname: Reiter
authors.forename: Oliver
authors.initials: O
authors.lastname: Schildgen
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000821:virology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005858:Germany; D006801:Humans; D011120:Polyomavirus; D027601:Polyomavirus Infections / Q000821:virology*; D012141:Respiratory Tract Infections / Q000821:virology*; D012189:Retrospective Studies