title: [Effect of arterial hypertension on sexual health of men and their quality of life. Resuts of BOLERO study].
abstract: Analysis of results of epidemiological BOLERO study showed that 2/3 of men with uncontrolled arterial hypertension noted problems in sexual life. Severity of problems in this sphere of life of men correlated positively with age, as well as with presence of difficulties at work, increased fatigability, impossibility to be involved in favorite activity (hobby), disturbances of nocturnal sleep (as assessed by GQLI questionnaire). As a result of 8 weeks therapy which included indapamide retard number of patients noting substantial influence of sexual problems on their habitual way of life (CQLI score >3) decreased almost 2 times (from 25 to 13%, p<0,001). At least 1 point decrease in evaluation of importance of such problems occurred in 33% of cases, 63% of patients did not change their score. An increase of GQLI score was noted in 4% of cases. Multifactorial analysis allowed to reveal that restoration of sexual function went parallel with improvement of quality of life related to recovery of psychosocial relationships and augmentation of physical activity. Moreover it was established that adequate lowering of arterial pressure in men during use of indapamide retard decreased risk of worsening of their sexual function.
authors.forename: R T
authors.initials: RT
authors.lastname: Saĭgitov
authors.forename: M G
authors.initials: MG
authors.lastname: Glezer
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000523:psychology*; D007190:Indapamide / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D012735:Sexual Dysfunction, Physiological / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D011795:Surveys and Questionnaires
chemical_list: D000959:Antihypertensive Agents; D007190:Indapamide