Effect of Saccharomyces cerevisiae fermentation product on immune functions of broilers challenged with Eimeria tenella.
Three hundred sixty 1-d-old male Arbor Acres broilers were randomly allotted to 6 groups with a 2x3 factorial arrangement of treatments. Three supplemental levels (0, 0.25, and 0.50%) of Saccharomyces cerevisiae fermentation product (XP) were fed to control and Eimeria tenella-infected broilers. Growth performance and immune response criteria were measured after coccidian infection. Broiler ADG was lowered (P<0.01) by coccidian infection and improved by XP supplementation (P=0.04). Supplementation of XP increased CD3+, CD4+, and CD8+ T-lymphocyte counts (P<0.05) and the ratio CD4+:CD8+ in blood (P=0.06) and spleen (P=0.04) as well as ileum intraepithelial lymphocyte count, cecal tonsil secretory IgA counts, serum lysozyme content (P<0.01), and albumin:globulin ratio (P=0.02). These results suggest that dietary XP supplementation could improve immune function and growth performance in coccidia-infected broilers.
Gao
J
J
Feed Research Institute, Chinese Academy of Agricultural Sciences & Key Laboratory of Feed Biotechnology, Ministry of Agriculture of China, Beijing 100081, China.
Zhang
H J
HJ
Wu
S G
SG
Yu
S H
SH
Yoon
I
I
Moore
D
D
Gao
Y P
YP
Yan
H J
HJ
Qi
G H
GH
D000818:Animals; D015703:Antigens, CD / Q000097:blood; D002432:Cecum / Q000469:parasitology; D002645:Chickens; D003048:Coccidiosis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D016786:Eimeria tenella / Q000276:immunology*; D007082:Ileum / Q000469:parasitology; D007070:Immunoglobulin A / Q000032:analysis; D007411:Intestinal Diseases, Parasitic / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D008297:Male; D009113:Muramidase / Q000097:blood; D011201:Poultry Diseases / Q000276:immunology / Q000469:parasitology*; D011897:Random Allocation; D012441:Saccharomyces cerevisiae / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology / Q000469:parasitology; D013601:T-Lymphocytes / Q000276:immunology / Q000469:parasitology
D015703:Antigens, CD; D007070:Immunoglobulin A; D009113:Muramidase