title: Fatal co-infection with swine origin influenza virus A/H1N1 and community-acquired methicillin-resistant Staphylococcus aureus.
abstract: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) co-infection has been described previously in association with respiratory tract infection caused by seasonal influenza A viruses, but not with swine origin influenza A (H1N1) virus (S-OIV). We report the clinical and pathological findings of the first death with fulminant co-infection by CA-MRSA. Since early empirical treatment with beta-lactam plus fluoroquinolone or macrolides is often initiated before specimen collections, bacterial co-infection in S-OIV may have been under-reported.
authors.affiliation: Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong, China.
authors.forename: Vincent C C
authors.initials: VC
authors.lastname: Cheng
authors.forename: Yuk-Kong
authors.initials: YK
authors.lastname: Lau
authors.forename: Kwok-Lun
authors.initials: KL
authors.lastname: Lee
authors.forename: Kwan-Ho
authors.initials: KH
authors.lastname: Yiu
authors.forename: Kwok-Hung
authors.initials: KH
authors.lastname: Chan
authors.forename: Pak-Leung
authors.initials: PL
authors.lastname: Ho
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
mesh_terms: D000328:Adult; D000956:Antigens, Viral / Q000302:isolation & purification; D017714:Community-Acquired Infections / Q000150:complications* / Q000175:diagnosis; D017809:Fatal Outcome; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000175:diagnosis; D008168:Lung / Q000382:microbiology / Q000473:pathology / Q000821:virology; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D013203:Staphylococcal Infections / Q000150:complications* / Q000175:diagnosis
chemical_list: D000956:Antigens, Viral