Lung cancer in never smokers: a call to action.
The causative association between tobacco use and lung cancer is a well-established fact. However, lung cancer also occurs, at surprisingly high rates, in lifelong never smokers. In fact, lung cancer in never smokers is among the leading causes of cancer-related mortality. This CCR Focus summarizes recent data, identifies knowledge deficits, and suggests future research directions with regard to this critically important subset of lung cancer patients.
Rudin
Charles M
CM
Johns Hopkins University, Baltimore, Maryland 21231, USA. rudin@jhmi.edu
Avila-Tang
Erika
E
Samet
Jonathan M
JM
D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects / Q000032:analysis
D014028:Tobacco Smoke Pollution