Usefulness and influence of age of a novel Rapid HpStAR stool antigen for the diagnosis of Helicobacter pylori infection in children.
A novel rapid monoclonal enzyme immunoassay stool antigen for Helicobacter pylori detection (Rapid HpStAR) was evaluated in 16 infected and 92 noninfected children. The overall sensitivity, specificity, and positive and negative predictive values were 87.5%, 97.8%, 87.5%, and 97.8%, respectively, with an accuracy of 96.2%. The negative predictive value was good in all age groups, reaching 100% in younger children.
Kalach
Nicolas
N
Clinique Pédiatrique Saint Antoine, Hôpital Saint Vincent de Paul, Université Catholique, Boulevard de Belfort, 59020 Lille, France.
Dehecq
Eric
E
Gosset
Pierre
P
Decoster
Anne
A
Bergeret
Michel
M
Dupont
Christophe
C
Raymond
Josette
J
D000293:Adolescent; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000737:chemistry* / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007223:Infant; D008297:Male; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic