Hereditary prothrombin deficiency.
Hereditary prothrombin deficiency is one of the rare congenital coagulation defects. We report a case of 4 months old child who initially presented at 11/2 month of age with high-grade fever, generalized convulsions and brownish aspirate through nasogastric tube, diagnosed and managed as meningitis and sepsis. He was readmitted at 4 months of age with bruises over legs. Coagulation profile was suggestive of common pathway defect. Further evaluation revealed absent prothrombin level while other factors were within normal limits.
Ejaz
Muzamil Shabana
MS
Department of Pediatrics, Civil Hospital, Karachi.
Latif
Nazia
N
Memon
Ashraf
A
D006801:Humans; D007020:Hypoprothrombinemias / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D007223:Infant; D008297:Male