title: Production of (R)-1-phenylethanols through bioreduction of acetophenones by a new fungus isolate Trichothecium roseum.
abstract: A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding (R)-alcohols. Among these strains, isolate Trichothecium roseum EBK-18 was highly effective in the production of (R)-alcohols with excellent enantioselectivity (ee > 99%). Gram scale preparation of (R)-1-phenylethanol is reported.
authors.affiliation: Faculty of Sciences, Department of Chemistry, Ataturk University, Erzurum 25240, Turkey.
authors.forename: Kani
authors.initials: K
authors.lastname: Zilbeyaz
authors.forename: Mesut
authors.initials: M
authors.lastname: Taskin
authors.forename: Esabi B
authors.initials: EB
authors.lastname: Kurbanoglu
authors.forename: Namudar I
authors.initials: NI
authors.lastname: Kurbanoglu
authors.forename: Hamdullah
authors.initials: H
authors.lastname: Kilic
mesh_terms: D000098:Acetophenones / Q000378:metabolism*; D006999:Hypocreales / Q000302:isolation & purification* / Q000378:metabolism*; D010084:Oxidation-Reduction; D010626:Phenylethyl Alcohol / Q000737:chemistry* / Q000378:metabolism*; D012988:Soil Microbiology; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000098:Acetophenones; D010626:Phenylethyl Alcohol; C038699:acetophenone