title: Uterine peristalsis in women with repeated IVF failures: possible therapeutic effect of hyoscine bromide.
abstract: BACKGROUND
  Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy.
  
  
  METHODS
  We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer.
  
  
  CONCLUSIONS
  It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto City, Kyoto, Japan.
authors.forename: Aki
authors.initials: A
authors.lastname: Kido
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto City, Kyoto, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
authors.affiliation: Adachi Hospital, Kyoto, Kyoto, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hatayama
authors.affiliation: Adachi Hospital, Kyoto, Kyoto, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakayama
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto City, Kyoto, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Yamamoto
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto City, Kyoto, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Kataoka
authors.affiliation: Department of Obstetrics and Gynecology, McGill University, Montreal QC.
authors.forename: Togas
authors.initials: T
authors.lastname: Tulandi
mesh_terms: D000328:Adult; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D010528:Peristalsis / Q000187:drug effects*; D011247:Pregnancy; D012601:Scopolamine / Q000627:therapeutic use*; D017211:Treatment Failure; D014590:Uterine Contraction / Q000187:drug effects*
chemical_list: D018680:Cholinergic Antagonists; D012601:Scopolamine