title: Detection of Helicobacter pylori using PCR in dental plaque of patients with and without gastritis.
abstract: OBJECTIVE
  Helicobacter pylori (H.pylori) accounts for gastritis, peptic ulcer and is a probable cause of gastric cancer. Since its detection in the oral cavity, concerns have been raised about dental plaque as a reservoir for reinfection. The aim of this study was to detect the organism in the dental plaque and to determine the association, if any, between H. pylori gastritis and dental plaque contamination causing H.pylori.
  
  
  METHODS
  A polymerase chain reaction-based method was used for detection of H. pylori in clinical specimens. Supra and subgingival samples were collected from 67 patients with chronic periodontitis, 23 of whom were also suffering from gastritis. The data were analyzed with Chi square and Fisher exact test and the statistical significance was set to 0.05.
  
  
  RESULTS
  H.pylori was scarce in patients with periodontitis(5.9%). There was a significant association between the presence of H.pylori in the dental plaque and gastritis (p=0.012).
  
  
  CONCLUSIONS
  Although rarely seen, H.pylori infected dental plaque may be a source for reinfection. It is therefore suggested that professional plaque removal and oral hygiene procedures be performed, along with the antibiotic treatment of H.pylori.
authors.affiliation: Department of Periodentics, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. amirr22@yahoo.com
authors.forename: Amir
authors.initials: A
authors.lastname: Eskandari
authors.forename: Ali
authors.initials: A
authors.lastname: Mahmoudpour
authors.forename: Nader
authors.initials: N
authors.lastname: Abolfazli
authors.forename: Ardeshir
authors.initials: A
authors.lastname: Lafzi
mesh_terms: D000328:Adult; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D005756:Gastritis / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction