Severe hyperphosphatemia in a newborn with renal insufficiency because of an erroneous medical prescription.
We report on an 8-day-old boy with renal failure attributable to bilateral vesicoureteral reflux and dysplastic kidneys. He developed hyperphosphatemia because of his oral phosphate intake. Because he had mild metabolic acidosis, alkaline therapy was planned, but through a medical prescription error he was given a phosphate instead of an alkaline solution. He developed carpopedal spasm, with calcium and phosphate at 5.3mg/dL and 26.0mg/dL, respectively. His phosphate levels gradually decreased via diuretic and calcium gluconate therapy, without dialysis.
Dissaneewate
Supaporn
S
Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand.
Vachvanichsanong
Prayong
P
D000138:Acidosis / Q000188:drug therapy; D002125:Calcium Gluconate / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D054559:Hyperphosphatemia / Q000139:chemically induced*; D007231:Infant, Newborn; D008297:Male; D008508:Medication Errors / Q000009:adverse effects*; D010710:Phosphates / Q000008:administration & dosage* / Q000009:adverse effects*; D051437:Renal Insufficiency / Q000188:drug therapy*; D012720:Severity of Illness Index
D004232:Diuretics; D010710:Phosphates; D002125:Calcium Gluconate