Simultaneous occurrence of renal oncocytoma and B small cell lymphoma in the same kidney: report of two cases.
Two cases of simultaneous occurrence of oncocytoma (OC) associated with small B-cell lymphoma in the same kidney were investigated. Computed tomography, performed for staging purposes, incidentally revealed a small hypo- and hyperattenuating renal mass. Diagnosis of OC was performed on the specimen by morphology, immunohistochemistry and electron microscopy. The patients are in complete remission after a vaccinotherapy with follicular dendritic cells. The occurrence of OC and non-Hodgkin lymphoma in the same kidney has never been reported. These case reports outline that computerized tomography is a sensitive method in the staging of lymphoma. However, when some solid, small hyper- or hypoattenuating masses occur in the kidney, the diagnosis by computed tomography alone is always a challenge and other malignant neoplasms may be considered. Immunohistochemistry and electron microscopy allow a definitive diagnosis of OC.
Nigro
Michele
M
Institute of Anatomic Pathology, Legnago Hospital, Legnago, Italy.
Piscioli
Irene
I
Franceschetti
Ilaria
I
Barberini
Francesco
F
Lupattelli
Luciano
L
Scialpi
Michele
M
D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000628:therapy; D000369:Aged, 80 and over; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000628:therapy; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000628:therapy