title: Identification and validation of a potent type II inhibitor of inactive polo-like kinase 1.
authors.affiliation: Department of Obstetrics & Gynecology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Sarah
authors.initials: S
authors.lastname: Keppner
authors.forename: Ewgenij
authors.initials: E
authors.lastname: Proschak
authors.forename: Gisbert
authors.initials: G
authors.lastname: Schneider
authors.forename: Birgit
authors.initials: B
authors.lastname: Spänkuch
mesh_terms: D001596:Benzylamines / Q000737:chemistry / Q000494:pharmacology*; D001665:Binding Sites; D018797:Cell Cycle Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D006367:HeLa Cells; D006801:Humans; D006860:Hydrogen Bonding; D008956:Models, Chemical; D010627:Phenethylamines / Q000737:chemistry / Q000494:pharmacology*; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D017434:Protein Structure, Tertiary; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D000097869:Polo-Like Kinase 1
chemical_list: D001596:Benzylamines; D018797:Cell Cycle Proteins; D010627:Phenethylamines; D047428:Protein Kinase Inhibitors; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D011725:Pyridines; D000097869:Polo-Like Kinase 1; C549033:SBE13 compound