title: Single and dual glycoside clustering around calix[4]arene scaffolds via click thiol-ene coupling and azide-alkyne cycloaddition.
abstract: We present the first synthesis of calix[4]arene-based S-glycoclusters via photoinduced multiple thiol-ene coupling of tetra- and octa-allyl calix[4]arenes with peracetylated glucosyl thiol (67-88% yields). Moreover we describe the dual clustering at the upper and lower rim of a calix[4]arene with two different sugars (galactose and glucose) via sequential copper(i)-catalyzed azide-alkyne cycloaddition and photoinduced thiol-ene coupling.
authors.affiliation: Dipartimento di Chimica, Laboratorio di Chimica Organica, Università di Ferrara, Via L. Borsari 46, 44100, Ferrara, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Fiore
authors.forename: Angela
authors.initials: A
authors.lastname: Chambery
authors.forename: Alberto
authors.initials: A
authors.lastname: Marra
authors.forename: Alessandro
authors.initials: A
authors.lastname: Dondoni