title: Large bronchial granular cell tumor.
abstract: We report a 20-year-old woman who underwent complete resection of a granular cell tumor (GCT). On chest computed tomography (CT) scan, a mass with a maximum diameter of 36 mm at the lower bronchus with atelectasis of the right lower lobe was noted. Bronchoscopic examination revealed a whitish mass in the truncus intermedius, and the middle and lower bronchus were unable to be seen. A cytopathological examination of the mass revealed GCT. A right middle and lower lobectomy was performed via a posterolateral thoracotomy. Microscopically, the tumor was composed of polygonal cells with oxyphilic granular cytoplasm and small ovoid nuclei. The cytoplasm of the neoplastic cells was positive for S-100 protein and neuron-specific enolase. The patient's postoperative course was uneventful, and she was asymptomatic after 4 months. A large bronchial GCT is rare, which is why we report this case.
authors.affiliation: Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. hirohiko@med.niigata-u.ac.jp
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Shinohara
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsuchida
authors.forename: Takehisa
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Seijirou
authors.initials: S
authors.lastname: Satoh
authors.forename: Mariko
authors.initials: M
authors.lastname: Takeshige
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Hayashi
mesh_terms: D001984:Bronchial Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000601:surgery*; D001999:Bronchoscopy; D005260:Female; D016586:Granular Cell Tumor / Q000737:chemistry / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D011013:Pneumonectomy; D009418:S100 Proteins / Q000032:analysis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase