An ultrasensitive electrochemical "turn-on" label-free biosensor for Hg2+with AuNP-functionalized reporter DNA as a signal amplifier.
A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNA thymine bases (T-Hg2+-T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.
Kong
Rong-Mei
RM
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
Zhang
Xiao-Bing
XB
Zhang
Liang-Liang
LL
Jin
Xiao-Yong
XY
Huan
Shuang-Yan
SY
Shen
Guo-Li
GL
Yu
Ru-Qin
RQ
D004247:DNA / Q000737:chemistry*; D021881:DNA, Catalytic / Q000737:chemistry; D004785:Environmental Pollutants / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D008628:Mercury / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry*; D013941:Thymine / Q000737:chemistry
D021881:DNA, Catalytic; D004785:Environmental Pollutants; D006046:Gold; D004247:DNA; D008628:Mercury; D013941:Thymine