title: [Symptomatic splenomegaly in a young Japanese man with sarcoidosis accompanied by spleen, liver, kidney, lung and lymph node lesions].
abstract: A 27-year-old man experienced progressive left hypochondralgia. CT with contrast medium enhancement revealed marked splenomegaly, multiple swollen lymph nodes in the mediastinum and abdominal cavity, and multiple nodules in the spleen, liver, kidneys and lungs. Pathological examinations of the lung and liver lesions showed non-caseating granulomatous lesions, and established the diagnosis of sarcoidosis. The symptom and lesions presented by CT regressed dramatically with administration of corticosteroid (30 mg/day oral prednisolone). Symptomatic splenomegaly in a young Japanese man with sarcoidosis seems very rare especially considering that sarcoidosis lesions completely regress spontaneously within a year in 90% patients of young Japanese men with sarcoidosis.
authors.affiliation: Department of Respirology, Graduate School of Medecine, Chiba University.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kitamura
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takiguchi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Sugiura
authors.forename: Satoru
authors.initials: S
authors.lastname: Kitazono
authors.forename: Katsushi
authors.initials: K
authors.lastname: Kurosu
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanabe
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kisimoto
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tatsumi
mesh_terms: D000328:Adult; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology*; D013154:Spleen / Q000473:pathology*; D013163:Splenomegaly / Q000150:complications*