Calycinumines A and B, two novel alkaloids from Daphniphyllum calycinum.
Two novel alkaloids, calycinumines A (1) and B (2), were isolated from the twigs of Daphniphyllum calycinum. Calycinumine A (1) is the first example of C-22-nor yuzurimine-type alkaloids, and calycinumine B (2) features an unprecedented heteroatom-containing adamantane-like western hemisphere of the alkaloid. Their structures were elucidated by spectroscopic methods, and that of 1 was confirmed by a single-crystal X-ray diffraction.
Zhang
Chuan-Rui
CR
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
Liu
Hong-Bing
HB
Dong
Shi-Hui
SH
Zhu
Jian-Yong
JY
Wu
Yan
Y
Yue
Jian-Min
JM
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D029624:Ferns / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation
D000470:Alkaloids; C545741:calycinumine A; C545742:calycinumine B