title: Spontaneous hematomyelia in a child with hemophilia A: a case report.
abstract: Hemorrhagic complications in patients with hemophilia have been occasionally reported in the spinal column and the spinal cord. Treatment is based on prompt replacement therapy as the occurrence and development of neurologic dysfunction are related to the length of time between the onset of symptoms and the factor replacement. We report case of a 7-year-old hemophilic boy who presented with flaccid paraparesis resulting from thoracic hematomyelia. The patient showed gradual improvement on medical management with cryoprecipitate infusions. This case calls attention to the need for prompt diagnosis of rarely reported spinal hematomyelia based on clinical manifestations and radiologic features and highlights its management options in patients with hemophilia.
authors.affiliation: Hemato-Oncology and Genetics Units, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab, India.
authors.forename: Roosy
authors.initials: R
authors.lastname: Aulakh
authors.forename: Inusha
authors.initials: I
authors.lastname: Panigrahi
authors.forename: Kirti
authors.initials: K
authors.lastname: Naranje
authors.forename: Sheetal
authors.initials: S
authors.lastname: Sharda
authors.forename: Ram K
authors.initials: RK
authors.lastname: Marwaha
mesh_terms: D002648:Child; D005169:Factor VIII / Q000627:therapeutic use; D005340:Fibrinogen / Q000627:therapeutic use; D006395:Hemarthrosis; D006467:Hemophilia A / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020758:Spinal Cord Vascular Diseases / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: C026912:cryoprecipitate coagulum; D005169:Factor VIII; D005340:Fibrinogen