Splenectomy-induced long-term remission in a patient with multicentric Castleman's disease.
Castleman's disease (CD) is a rare lymphoproliferative disorder with a poorly understood pathogenesis. Multicentric CD can progress in different patterns, none of which can be cured with the current treatment options. We present a patient with multicentric CD in complete remission, eight years after a splenectomy without any other systemic treatment. We discuss the possible mechanism causing this long episode of complete remission in this patient.
Bos
M M E M
MM
Department of Internal Medicine, Reinier de Graaf Group, Delft, the Netherlands. Bos@rdgg.nl
van den Berg
L M
LM
van Leeuwen
A W F M
AW
Posthuma
E F M
EF
D000328:Adult; D005871:Castleman Disease / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D013156:Splenectomy; D013997:Time Factors