Kindling as a model of human epilepsy.
The evidence supporting the suggestion that kindling is a good model of human temporal lobe epilepsy is briefly reviewed. Parallels between the human condition, involving both partial and secondarily generalized seizures, and kindling in rats and other animals are drawn and contrasted.
McIntyre
Dan C
DC
Department of Psychology, Institute of Neuroscience, Carleton University, Ottawa, Ontario, Canada.
Gilby
Krista L
KL
D000818:Animals; D004195:Disease Models, Animal; D004558:Electric Stimulation; D004569:Electroencephalography / Q000379:methods; D004827:Epilepsy / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007696:Kindling, Neurologic / Q000502:physiology*; D051381:Rats