Synthesis and hybridization of oligonucleotides attached to a redox reporter via ethenyl linker at 5-position of pyrimidine base.
We describe a new ferrocene-based redox-reporter that electronically couples to the DNA Pi-electron system.
Hasegawa
Yusuke
Y
Department of Materials Science and Chemistry, Universty of Hyogo, Himeji, Hyogo 671-2201, Japan.
Nakamura
Mitsunobu
M
Takada
Tadao
T
Yamana
Kazushige
K
D020137:Base Pair Mismatch; D004247:DNA / Q000737:chemistry; D004252:DNA Mutational Analysis / Q000379:methods*; D055664:Electrochemical Techniques; D005296:Ferrous Compounds / Q000737:chemistry; D000075163:Metallocenes; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D013050:Spectrometry, Fluorescence; D014529:Uridine / Q000031:analogs & derivatives* / Q000737:chemistry
D005296:Ferrous Compounds; D000075163:Metallocenes; D015345:Oligonucleotide Probes; D004247:DNA; C004998:ferrocene; D014529:Uridine