title: [A case of advanced cancer of the gastric remnant with complete response to S-1 plus docetaxel chemotherapy as confirmed histopathologically].
abstract: A 64-year-old man underwent a probe laparotomy for unresectable gastric remnant cancer (GRC) involving the pancreas and retroperitoneum. Combination chemotherapy with S-1 and docetaxel was given after surgery. Computed tomography and endoscopy showed tumor shrinkage after two courses of chemotherapy. After 6 courses, endoscopic examination revealed a small ulcer. Although no cancer cells were found in a biopsy specimen, we were unable to conclude that such cells had disappeared completely. The patient underwent resection of GRC with pancreatosplenectomy. The remnant stomach could not be dissected from the pancreas, and we suspected the presence of residual cancer cells. The tumor was found to have had a complete response (CR) to combination chemotherapy on histopathological examination.
authors.affiliation: Dept. of Esophago-Gastric Surgery, Tokyo Medical and Dental University.
authors.forename: Mikito
authors.initials: M
authors.lastname: Inokuchi
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Kojima
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamada
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Sugita
authors.forename: Sho
authors.initials: S
authors.lastname: Otsuki
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Kawano
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sugihara
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000077143:Docetaxel; D004338:Drug Combinations; D018530:Gastric Stump; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D010180:Pancreatectomy; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid