title: Rational design of improved pharmabiotics.
abstract: Herein we review the most recent advances in probiotic research and applications with particular emphasis on the novel concept of patho-biotechnology: the application of pathogen-derived (ex vivo and in vivo) stress survival strategies for the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications.
authors.affiliation: Alimentary Pharmabiotic Centre, University College Cork, Ireland. roy.sleator@cit.ie
authors.forename: Roy D
authors.initials: RD
authors.lastname: Sleator
authors.forename: Colin
authors.initials: C
authors.lastname: Hill
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods*; D006801:Humans; D019936:Probiotics / Q000737:chemistry* / Q000494:pharmacology*