title: [A clinical and therapeutic analysis in acute megakaryoblastic leukemia].
abstract: OBJECTIVE
  to show clinical and therapeutic findings in patients with diagnosis of acute megakaryoblastic leukemia (AML).
  
  
  METHODS
  twenty four patients with diagnosis AML was carried out. Clinical, laboratory survey results and treatment response were studied. Nineteen patients had primary form and five secondary, attended during a period of eight years. The diagnosis was established by a highly clinical suspicious, with immunophenotype cytometry flow or/and bone biopsy with immunohistochemistry study which proves definitely AML.
  
  
  RESULTS
  Fourteen were women, the median age was 43 years, 18 were treated with antineoplasic agents, ten obtained response, six complete and four partial. The response may improve with schemes with high dose of cytosine arabinoside.
  
  
  CONCLUSIONS
  our results with the treatment showed that 27 % patients are alive under maintenance treatment long 18 months. The allogeneic bone marrow transplant seems to be one more option in long term.
authors.affiliation: Servicio de Hematología, Hospital de Especialidades, Centro Médico Nacional de Occidente, Guadalajara Instituto Mexicano del Seguro Social, Jalisco, Mexico. delgado_lamas2002@hotmail.com
authors.forename: José Luis
authors.initials: JL
authors.lastname: Delgado-Lamas
authors.forename: Oscar Miguel
authors.initials: OM
authors.lastname: Garcés-Ruiz
authors.forename: Lilia Beatriz
authors.initials: LB
authors.lastname: Aguilar-López
authors.forename: César
authors.initials: C
authors.lastname: Borjas-Gutiérrez
authors.forename: María Rosa
authors.initials: MR
authors.lastname: Flores-Márquez
authors.forename: Hilda
authors.initials: H
authors.lastname: Luna-Zaizar
authors.forename: Raúl
authors.initials: R
authors.lastname: Delgado-Chávez
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007947:Leukemia, Megakaryoblastic, Acute / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult