Chemical synthesis in microreactors.
To develop a new generation of drugs, pharmaceutical companies need to be able to synthesise and screen novel chemicals with enhanced speed. New technology that would enable a cost neutral step change in the number of potential drug candidates would provide a distinct competitive advantage. Indeed the miniaturisation of chemical reactors offers many fundamental and practical advantages of relevance to the pharmaceutical industry, who are constantly searching for controllable, information-rich, high-throughput, environmentally friendly methods of producing products with a high degree of chemical selectivity. This chapter reviews the current and future applications of microreactors that could enhance the drug discovery process.
Watts
Paul
P
Department of Chemistry, University of Hull, Hull, UK.
Haswell
Stephen J
SJ
D053841:Electroosmosis / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D008832:Microchemistry / Q000295:instrumentation* / Q000379:methods*; D010455:Peptides / Q000138:chemical synthesis; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000302:isolation & purification; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods
D010455:Peptides; D004364:Pharmaceutical Preparations