Ultrasound assisted green synthesis of bis(indol-3-yl)methanes catalyzed by 1-hexenesulphonic acid sodium salt.
1-Hexenesulphonic acid sodium salt as catalyst for green synthesis of bis(indol-3-yl)methanes was described. The reaction of indole with various aldehydes in water using ultrasound irradiation at ambient temperature for appropriate time using 1-hexenesulphonic acid sodium salt furnish the desired product in good to excellent yield. Utilization of aqueous medium, simple reaction conditions, isolation, and purification makes this manipulation very interesting from an economic and environmental perspective.
Joshi
Ratnadeep S
RS
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India.
Mandhane
Priyanka G
PG
Diwakar
Santosh D
SD
Gill
Charansingh H
CH
D000447:Aldehydes / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D000840:Anisoles / Q000138:chemical synthesis*; D002625:Chemistry, Organic / Q000379:methods; D055772:Green Chemistry Technology; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008697:Methane / Q000737:chemistry; D008956:Models, Chemical; D012997:Solvents / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors; D014465:Ultrasonics; D014867:Water / Q000737:chemistry
C545255:1,1-bis(3'-indolyl)-1-(p-anisyl)methane; D000447:Aldehydes; D000475:Alkenes; D000840:Anisoles; D007211:Indoles; D012997:Solvents; D013451:Sulfonic Acids; D014867:Water; C117224:1-hexene; D008697:Methane