Two "childhood" malignancies in an elderly individual: a case report and discussion.
Rhabdomyosarcoma (RMS) is the most common soft-tissue tumor in childhood, but is extremely rare in elderly. We present a rare case of cardiac RMS, which developed 1 year after the diagnosis and management of acute lymphoblastic leukemia in a 68-year-old female. The occurrence of such phenomena is intriguing, especially in an individual without prior history of malignancy at a younger age. Through the review of the existing literature, we attempt to approach the pathogenesis and clinical manifestations of this rare clinical entity.
Bachegowda
Lohith S
LS
Department of Internal Medicine, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, PA 19102, USA.
Nagaraj
Gayathri
G
Grivas
Petros D
PD
Chen
Lingyi
L
Choi
Eugene
E
Styler
Michael
M
D017668:Age of Onset; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000209:etiology; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D013997:Time Factors