A single slow electron triggers the loss of both chlorine atoms from the anticancer drug cisplatin: implications for chemoradiation therapy.
Kopyra
Janina
J
Chemistry Department, University of Podlasie, 3 Maja 54, 08-110 Siedlce, Poland. kopyra@ap.siedlce.pl
Koenig-Lehmann
Constanze
C
Bald
Ilko
I
Illenberger
Eugen
E
D000970:Antineoplastic Agents / Q000737:chemistry / Q000528:radiation effects*; D002713:Chlorine / Q000737:chemistry*; D002945:Cisplatin / Q000737:chemistry / Q000528:radiation effects*; D018736:DNA Adducts / Q000737:chemistry; D004261:DNA Replication / Q000187:drug effects / Q000528:radiation effects; D004579:Electron Transport / Q000528:radiation effects; D004583:Electrons; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D011838:Radiation-Sensitizing Agents / Q000737:chemistry / Q000528:radiation effects*
D000970:Antineoplastic Agents; D018736:DNA Adducts; D011838:Radiation-Sensitizing Agents; D002713:Chlorine; D002945:Cisplatin