Refractory anaemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) and JAK2(V617F) mutation transformed to acute myeloid leukaemia with chromosomal evolution including monosomy 7.
Pich
Achille
A
Godio
Laura
L
D000368:Aged; D000754:Anemia, Refractory, with Excess of Blasts / Q000150:complications / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000473:pathology; D002869:Chromosome Aberrations; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics; D015470:Leukemia, Myeloid, Acute / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D009006:Monosomy; D020125:Mutation, Missense; D013922:Thrombocytosis / Q000209:etiology
C507924:JAK2 protein, human; D053614:Janus Kinase 2