New treatment with human atrial natriuretic peptide for postoperative myonephropathic metabolic syndrome.
A 49-year-old man had sudden chest pain and paralysis of the lower right limb. An acute aortic dissection was diagnosed in a computed tomography scan and the patient underwent an emergency operation. After the operation, myonephropathic metabolic syndrome developed, and human atrial natriuretic peptide was administered for 11 days until the volume of daily urine output reached at least 10,000 mL, which would facilitate limb salvage and the preservation of life without hemodialysis. This report documents that postoperative myonephropathic metabolic syndrome improved due to the strong diuretic action of human atrial natriuretic peptide without hemodialysis.
Sezai
Akira
A
The Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan. asezai@med.nihon-u.ac.jp
Hata
Mitsumasa
M
Niino
Tesuya
T
Yoshitake
Isamu
I
Unosawa
Satoshi
S
Umezawa
Hisaki
H
Minami
Kazutomo
K
D000208:Acute Disease; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D009320:Atrial Natriuretic Factor / Q000008:administration & dosage*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008659:Metabolic Diseases / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D011183:Postoperative Complications; D011859:Radiography; D012206:Rhabdomyolysis / Q000188:drug therapy* / Q000209:etiology; D013577:Syndrome
D009320:Atrial Natriuretic Factor