Langerhans cell histiocytosis revealed by painful hip: a case report.
Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.
Sabeur
Hammami
H
Paediatric Department, Fattouma Bourguiba Hospital, Monastir, Tunisia. hamami_sabeur@yahoo.fr
Chebil
B Meriem
BM
Karim
B Ameur
BA
Samir
Hadded
H
Leila
Ghédira
G
Chiraz
Hafsa
H
Slaheddine
Chouchane
C
Néji
Guediche Mohamed
GM
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D007839:Functional Laterality; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D010026:Osteosclerosis / Q000000981:diagnostic imaging; D010031:Otitis / Q000175:diagnosis; D010146:Pain / Q000209:etiology; D011859:Radiography; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones