TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p.
Jasek
M
M
Gondek
L P
LP
Bejanyan
N
N
Tiu
R
R
Huh
J
J
Theil
K S
KS
O'Keefe
C
C
McDevitt
M A
MA
Maciejewski
J P
JP
D002872:Chromosome Deletion; D002886:Chromosomes, Human, Pair 17; D018628:Gene Dosage; D016158:Genes, p53; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D019656:Loss of Heterozygosity; D009154:Mutation; D009190:Myelodysplastic Syndromes / Q000235:genetics*