Bag-SPE--a convenient extraction method for screening of pharmaceutical residues in influent and effluent water from sewage treatment plants.
Bag-SPE is a solid-phase extraction (SPE) technique here applied to sample pharmaceutical residues in wastewater. The device, consisting of 20 mg polystyrene-divinylbenzene (PS-DVB) enclosed in a woven polyester fabric was immersed into a 20-mL sample. Extraction of the analytes was performed under gentle rotation (25 rpm) until distribution equilibrium was achieved (4 h). The extraction efficiency for thirteen pharmaceuticals was evaluated for the bag-SPE sampler compared to a conventional SPE cartridge (Oasis HLB). All analyses were determined on an ultra-performance liquid chromatography (UPLC) coupled to a quadrupole time-of-flight (QToF) mass spectrometer. The detection limit of the bag-SPE technique for the analytes in wastewater ranged from 15-100 ng/L with recoveries between 20.7% and 58.2% and ion suppressions between 2.2% and 53.2%. Although the extraction efficiencies were lower with the bag-SPE sampler compared to the SPE technique, the two methods showed similar detection limits due to the lower ion suppression experienced with the bag-SPE. The results demonstrate that bag-SPE is an attractive alternative to the more, in terms of manual handling, demanding SPE technique.
Magnér
J A
JA
Department of Applied Environmental Science, Stockholm University, SE-10691 Stockholm, Sweden. jorgen.magner@itm.su.se
Alsberg
T E
TE
Broman
D
D
D002853:Chromatography, Liquid; D013058:Mass Spectrometry; D015394:Molecular Structure; D015203:Reproducibility of Results; D012722:Sewage / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014867:Water / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification / Q000379:methods*
D012722:Sewage; D014874:Water Pollutants, Chemical; D014867:Water