title: [Stent-graft treatment of the descending thoracic aorta in high risk patients].
abstract: OBJECTIVE
  To report our experience with endovascular stent-graft repair of descending thoracic aorta diseases in high risk patients.
  
  
  METHODS
  Between 2000 and 2007, 49 high surgical risk patients (mean age: 64.6 years) underwent stent-graft placement, including 24 cases presenting acutely. Mean follow-up was 25.4 months. Etiologies included 15 aneurysms, 11 dissections, 10 penetrating ulcers, 9 false aneurysms, 2 ruptures of the aortic isthmus, 2 intramural hematomas.
  
  
  RESULTS
  Access failure occurred in one patient. The overall mortality was 27.1% (n=13), nine related to the presenting pathology or treatment. Thirty-day mortality was 10.4% (n=5). Complications included vascular injury at the iliac or femoral artery access (10.2%), 1 case of flaccid paraplegia, 2 cases of transient paraparesis, 2 strokes, 2 stent migrations and 1 stent rupture. The rate of early endoleak was 39.6% while the rate of delayed endoleak was 14.6%. Seven patients (14.6%) required repeat endovascular interventions. Explantation was required in 2 cases. The latest available follow-up showed no lesion enlargement in 70.7% (n=29/41) of our patients.
  
  
  CONCLUSIONS
  Descending thoracic aortic pathology can be treated using endografts in high risk patients, although significant morbidity and mortality remain. Because of the high rate of endoleaks, close follow-up is required.
authors.affiliation: Service de Radiologie, CHU Pontchaillou, 2, rue H. Le Guillou, 35033 Rennes cedex 9.
authors.forename: P A
authors.initials: PA
authors.lastname: Lentz
authors.forename: J P
authors.initials: JP
authors.lastname: Verhoye
authors.forename: A
authors.initials: A
authors.lastname: Larralde
authors.forename: J
authors.initials: J
authors.lastname: David
authors.forename: J F
authors.initials: JF
authors.lastname: Heautot
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000601:surgery*; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013902:Radiography, Thoracic; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods