title: Synthesis of phthalocyanines-ALA conjugates: water-soluble compounds with low aggregation.
abstract: Syntheses of two water-soluble phthalocyanines (Pc) containing 5-aminolevulinic acid (ALA) linked to the core structure are described. These compounds were prepared by using original functionalizations, and they present remarkable structural and photophysical features, indicating that they could be applied to photodynamic therapy (PDT).
authors.affiliation: Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Av. Bandeirantes 3900, 14040-901, Ribeirão Preto-SP, Brazil. kleber.oliveira@ufabc.edu.br
authors.forename: Kleber T
authors.initials: KT
authors.lastname: de Oliveira
authors.forename: Francisco F
authors.initials: FF
authors.lastname: de Assis
authors.forename: Anderson O
authors.initials: AO
authors.lastname: Ribeiro
authors.forename: Claudio R
authors.initials: CR
authors.lastname: Neri
authors.forename: Adjaci U
authors.initials: AU
authors.lastname: Fernandes
authors.forename: Mauricio S
authors.initials: MS
authors.lastname: Baptista
authors.forename: Norberto P
authors.initials: NP
authors.lastname: Lopes
authors.forename: Osvaldo A
authors.initials: OA
authors.lastname: Serra
authors.forename: Yassuko
authors.initials: Y
authors.lastname: Iamamoto
mesh_terms: D000622:Aminolevulinic Acid / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D054833:Isoindoles; D015394:Molecular Structure; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D007211:Indoles; D054833:Isoindoles; D014867:Water; D000622:Aminolevulinic Acid; C013647:phthalocyanine