title: FIGfams: yet another set of protein families.
abstract: We present FIGfams, a new collection of over 100,000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried out, ensuring a previously unattained degree of throughput and consistency. FIGfams are based on over 950,000 manually annotated proteins and across many hundred Bacteria and Archaea. Associated with each FIGfam is a two-tiered, rapid, accurate decision procedure to determine family membership for new proteins. FIGfams are freely available under an open source license. These can be downloaded at ftp://ftp.theseed.org/FIGfams/. The web site for FIGfams is http://www.theseed.org/wiki/FIGfams/
authors.affiliation: Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, USA. folker@anl.gov
authors.forename: Folker
authors.initials: F
authors.lastname: Meyer
authors.forename: Ross
authors.initials: R
authors.lastname: Overbeek
authors.forename: Alex
authors.initials: A
authors.lastname: Rodriguez
mesh_terms: D019843:Archaeal Proteins / Q000145:classification; D001426:Bacterial Proteins / Q000145:classification; D011506:Proteins / Q000145:classification* / Q000235:genetics; D012269:Ribosomal Proteins / Q000145:classification; D012984:Software
chemical_list: D019843:Archaeal Proteins; D001426:Bacterial Proteins; D011506:Proteins; D012269:Ribosomal Proteins