title: Synthesis and properties of new RNA molecules incorporating 2'-O-aryluridine derivatives.
abstract: A variety of 2'-O-arylnucleosides with functional groups were synthesized by the microwave-assisted reaction of 2,2'-anhydrouridine with phenol derivatives. The 2'-O-arylnucleosides thus obtained were incorporated into 2'-O-Me RNA or DNA oligomers and their hybridization properties were studied by T(m) measurements.
authors.affiliation: Department of Life Science, Graduate School of Bioscience and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Oeda
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Iijima
authors.forename: Hirosuke
authors.initials: H
authors.lastname: Tsunoda
authors.forename: Akihiro
authors.initials: A
authors.lastname: Okubo
authors.forename: Kohji
authors.initials: K
authors.lastname: Seio
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Sekine
mesh_terms: D004247:DNA / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry; D012313:RNA / Q000138:chemical synthesis / Q000737:chemistry*; D014529:Uridine / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D009705:Nucleosides; D012313:RNA; D004247:DNA; D014529:Uridine