title: Up to twenty-five-year survival after aortic valve replacement with size 19 mm valves.
abstract: Long-term survival was investigated in 202 patients who underwent isolated aortic valve replacement (AVR) with 19 mm valves. There were 171 women with a mean age of 69+/-9 years and 31 men with a mean age of 64+/-13 years. Patients had a mean body surface area of 1.61+/-0.13 m(2). Patient-prosthesis mismatch was moderate in 196 and severe in six patients. The mean follow-up for all patients was 78 months. There were 79 late deaths. The actuarial survival rates for all patients were 95+/-1% at 1 year, 75+/-2% at 5 years, 56+/-2% at 10 years, 41+/-2% at 15 years, 34+/-3% at 20 years and 34+/-2% at 25 years. Patients over 70 years old had a lower survival rate (P=0.0001). There were significant differences between ejection fraction (EF) >55% and EF <55% (P=0.0305). AVR with 19 mm valves appeared to provide satisfactory mid-term survival. Age and low EF were risk factors for shorter survival.
authors.affiliation: Department of Cardiovascular Surgery, Clinic and University Hospital of Santiago de Compostela, Spain. framan1@hotmail.com
authors.forename: Jose
authors.initials: J
authors.lastname: Rubio Alvarez
authors.forename: Juan
authors.initials: J
authors.lastname: Sierra Quiroga
authors.forename: Marino
authors.initials: M
authors.lastname: Vega Fernandez
authors.forename: Belen
authors.initials: B
authors.lastname: Adrio Nazar
authors.forename: Francisco
authors.initials: F
authors.lastname: Gude Sampedro
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Martinez Comendador
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Martinez Cereijo
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Alves Perez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D001830:Body Surface Area; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation* / Q000401:mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D011474:Prosthesis Design; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013318:Stroke Volume; D017741:Survivors; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left