SPI-7: Salmonella's Vi-encoding Pathogenicity Island.
Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease. As well as encoding genes which may aid its own transmission, it carries genes for potential virulence factors such as Vi antigen, SopE effector and type IVB pili. The stability of SPI-7 is of interest with respect to typhoid fever and related vaccines.
Seth-Smith
Helena M B
HM
Pathogen Sequencing Unit, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, United Kingdom. hss@sanger.ac.uk
D001426:Bacterial Proteins / Q000235:genetics; D036781:Fimbriae Proteins / Q000235:genetics; D044404:Genomic Islands; D006801:Humans; D011135:Polysaccharides, Bacterial / Q000235:genetics*; D012485:Salmonella typhi / Q000145:classification / Q000235:genetics*
D001426:Bacterial Proteins; D011135:Polysaccharides, Bacterial; C103987:SopE protein, Salmonella; C054154:capsular polysaccharide, Salmonella; C508415:type IVB pili, Salmonella typhi; D036781:Fimbriae Proteins