title: [Proctological surgery: advantages derived from the use of an innovative detergent in the post-operative period].
abstract: BACKGROUND
  This study was aimed to verify the efficacy, in terms of healing, reepithelization and discomfort, of a detergent cream to be locally used after surgery for the most frequent pathologies of anal canal and perineal region.
  
  
  METHODS
  The study was carried out on a "presentation sample" of 40 patients, 30 with clinico-instrumental diagnosis of III-IV degree haemorrhoids, 10 with diagnosis of chronic anal fissures, provided by 5 Colonproctological Centers, who entered a clinical follow-up after colonproctological surgery for their respective pathologies. The tested detergent cream (Anonet liquid) is composed by natural substances, such as Aloe vera, Hamamelis, Calendule e Hippocastane, as the lenitive and antiinflammatory principles, and Elastine, as a stimulatory agent of dermal elastic fibers, plus zincus oxide that has a protective, reparative and lenitive action, rice's starch with an anti-inflammatory action, liver fish oil and potassium glicirizzinate with high lenitive and anti-inflammatory action. The product does not contain strong tensioactive substances as well as preservants. The patients were asked to apply the cream on the perianal and perineal region twice a day for at least 12 days after surgery.
  
  
  RESULTS
  The study demonstrated that in 84% of tested patients the prescribed cream has favoured the prevention of infective complications by stimulating a normal reepithelization, and diminished the anal discomfort related to burning and pruritus. The cream did not cause irritative and allergic manifestations, skin damage as well as pharmacological toxicity.
  
  
  CONCLUSIONS
  The post-surgical use of the tested detergent cream, composed by the above-cited active principles, is recommended for locally preventing the infections, promoting the reepithelization, minimizing the perineal discomfort in patients operated of haemorrhoids and anal fissures.
authors.affiliation: Dipartimento di Chirurgia Generale e Trapianti d'Organo, Istituto 'Paride Stefanini', Università Sapienza, Roma, Italia. fagaj@tin.it
authors.forename: F
authors.initials: F
authors.lastname: Gaj
authors.forename: P
authors.initials: P
authors.lastname: Crispino
mesh_terms: D000328:Adult; D003902:Detergents / Q000627:therapeutic use*; D013505:Digestive System Surgical Procedures; D005260:Female; D005401:Fissure in Ano / Q000601:surgery*; D006484:Hemorrhoids / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care
chemical_list: D003902:Detergents