title: Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment.
authors.affiliation: NeuroCure Clinical Research Center, Charité-Universitaetsmedizin Berlin, 10117 Berlin, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Dörr
authors.forename: A
authors.initials: A
authors.lastname: Bitsch
authors.forename: K J G
authors.initials: KJ
authors.lastname: Schmailzl
authors.forename: A
authors.initials: A
authors.lastname: Chan
authors.forename: N
authors.initials: N
authors.lastname: von Ahsen
authors.forename: M
authors.initials: M
authors.lastname: Hummel
authors.forename: R
authors.initials: R
authors.lastname: Varon
authors.forename: C M
authors.initials: CM
authors.lastname: Lill
authors.forename: H-P
authors.initials: HP
authors.lastname: Vogel
authors.forename: F
authors.initials: F
authors.lastname: Zipp
authors.forename: Friedemann
authors.initials: F
authors.lastname: Paul
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000503:physiopathology; D024061:Collagen Type III / Q000032:analysis / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004351:Drug Resistance / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006333:Heart Failure / Q000139:chemically induced* / Q000503:physiopathology; D006801:Humans; D008942:Mitoxantrone / Q000009:adverse effects*; D009103:Multiple Sclerosis / Q000188:drug therapy*; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D009363:Neoplasm Proteins / Q000235:genetics; D011110:Polymorphism, Genetic / Q000235:genetics; D011654:Pulmonary Edema / Q000139:chemically induced / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000503:physiopathology
chemical_list: C513055:ABCB1 protein, human; C116614:ABCG2 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters; D000970:Antineoplastic Agents; D024061:Collagen Type III; D009363:Neoplasm Proteins; D008942:Mitoxantrone