Test-retest reliability of p13n23 and n34p44 components of vestibular evoked myogenic potentials in a large healthy population.
OBJECTIVE
The aim of this study is to evaluate the reliability of the VEMP characteristics recorded in a large number of healthy subjects.


METHODS
VEMP response was obtained on 75 healthy volunteers. Thirty-nine (39) of them were males and 36 were females. Their age varied between 25 and 63 years (mean value 43). Recording was achieved using monaural acoustic stimulation and ipsilateral muscle contraction. Latencies of p13, n23, n34, p44 peaks, p13n23 and n34p44 amplitudes and the interaural amplitude differences (IAD) were assessed.


RESULTS
The stability of latencies, amplitudes of the first p12-n23 and second n34-p44 waveforms was verified. The second complex was present in 76%. No factor indicates statistically significant side difference for both runs. IAD variable was not statistically different from zero in all cases. Results show very good reliability for amplitudes, good for some latencies, poor for some other latencies and IAD34-44 and very poor for IAD13-23. No strong and significant correlations were also found between IAD34-44 and IAD13-23 and between p13n23 and n34p44 amplitudes.


CONCLUSIONS
It is the first time that optimal latencies and amplitudes for early and late components of VEMP are described in a large sample of healthy subjects. The p13, n23, n34 and p44 latencies and p13-n23, and n34-p44 amplitudes were reliable, verifying that the method is reproducible and feasible. The IAD13-23 has the disadvantage of low reliability.
Eleftheriadou
Anna
A
ENT Department, Hippokration Hospital, Athens National University, Athens, Greece. aegika@yahoo.gr
Deftereos
Spyros
S
Zarikas
Vasilios
V
Panagopoulos
Grigoris
G
Sfetsos
Sotirios
S
Karageorgiou
Klimentini
K
Ferekidou
Elisa
E
Korres
Stavros
S
Kandiloros
Dimitrios
D
D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D005071:Evoked Potentials / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D011930:Reaction Time; D015203:Reproducibility of Results; D014724:Vestibular Function Tests; D014722:Vestibule, Labyrinth / Q000502:physiology*