A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers.
A versatile and high yielding one-pot hydroformylation/Strecker synthesis is reported for the synthesis of various alpha-aminonitriles. This methodology allows functionalization of dendrimers (e.g. polyamines 4-7) and hyper branched polymers (e.g. polyallyl glycerol 12) to give corresponding dendritic structures with alpha-aminonitriles and/or amino acids in the outer shell in good to excellent yields.
Subhani
Muhammad Afzal
MA
Universität Dortmund, Fachbereich Chemie, Organische Chemie I, Otto-Hahn-Str. 6, 44227, Dortmund, Germany.
Müller
Kai-Sven
KS
Koç
Fikret
F
Eilbracht
Peter
P
D000475:Alkenes / Q000737:chemistry; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry*; D006856:Hydrogen Cyanide / Q000737:chemistry; D009570:Nitriles / Q000737:chemistry; D011073:Polyamines / Q000737:chemistry; D013237:Stereoisomerism
D000475:Alkenes; D050091:Dendrimers; D009570:Nitriles; D011073:Polyamines; D006856:Hydrogen Cyanide