title: Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molar.
abstract: OBJECTIVE
  We compared the anesthetic efficacy of inferior alveolar nerve block (IANB) plus buccal infiltration (BI) and IANB plus periodontal ligament (PDL) articaine injections in patients with irreversible pulpitis in the mandibular first molar.
  
  
  METHODS
  Fifty-seven volunteers, patients with irreversible pulpitis in the mandibular first molar admitted to the Department of Stomatology, Second Affiliated Hospital, Sun Yat-Sen University, randomly received conventional IANB, containing 1.7 mL 4% articaine/HCl with 1:100,000 epinephrine, plus either BI or PDL injections containing 0.4 mL articaine/HCl with 1:100,000 epinephrine. The patients recorded the pain of the injections and endodontic access on a Heft-Parker visual analog scale (VAS).
  
  
  RESULTS
  According to the VAS scores, all patients experienced no or mild pain with BI and PDL injections after the application of IANB. Anesthetic success occurred in 81.48% for IANB plus BI (IANB/BI) compared with 83.33% for IANB plus PDL injection (IANB/PDL injection). None of the observed differences between the 2 groups was significant (P > .05).
  
  
  CONCLUSIONS
  Both injection combinations resulted in high anesthetic success in patients with irreversible pulpitis in the mandibular first molar.
authors.affiliation: Department of Stomatology, the Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Song
authors.initials: S
authors.lastname: Fan
authors.forename: Wei-liang
authors.initials: WL
authors.lastname: Chen
authors.forename: Cao-bing
authors.initials: CB
authors.lastname: Pan
authors.forename: Zhi-quan
authors.initials: ZQ
authors.lastname: Huang
authors.forename: Min-qian
authors.initials: MQ
authors.lastname: Xian
authors.forename: Zhao-hui
authors.initials: ZH
authors.lastname: Yang
authors.forename: Eduardo
authors.initials: E
authors.lastname: Dias-Ribeiro
authors.forename: Yan-can
authors.initials: YC
authors.lastname: Liang
authors.forename: Jiu-yang
authors.initials: JY
authors.lastname: Jiao
authors.forename: Yu-shan
authors.initials: YS
authors.lastname: Ye
authors.forename: Ting Yu
authors.initials: TY
authors.lastname: Wen
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental / Q000379:methods*; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002355:Carticaine / Q000008:administration & dosage; D002610:Cheek; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008334:Mandible; D008340:Mandibular Nerve; D008875:Middle Aged; D008963:Molar; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D010513:Periodontal Ligament; D011671:Pulpitis / Q000628:therapy*; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local; D002355:Carticaine