Serum clinical chemistry and hematology reference values in outbred stocks of albino mice from three commonly used vendors and two inbred strains of albino mice.
Reference values for serum clinical chemistry and hematology parameters are often sought after when attempting to interpret clinical pathology data. Furthermore, the values of parameters may vary between laboratories depending on the techniques being used. Accordingly, laboratories should strive to generate a historical reference value database based upon the methods used. Published reference values can provide an investigator with a useful tool with which to begin the evaluation of data, especially if the laboratory of concern does not have sufficient historical data on the inbred strain or outbred stock of mouse being evaluated. We present the hematology and serum chemistry values of eight different outbred stocks and two separate inbred strains of mice in order to provide reference values that may aid in the scientific and medical interpretation of murine clinical pathology data.
Serfilippi
Laurie M
LM
Calvert Laboratories, Inc., Olyphant, Pennsylvania 18447, USA.
Pallman
Danielle R Stackhouse
DR
Russell
Bonita
B
D000818:Animals; D001772:Blood Cell Count; D001774:Blood Chemical Analysis / Q000662:veterinary*; D005260:Female; D006824:Hybridization, Genetic; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012016:Reference Values; D012727:Sex Characteristics