title: Breed, gender and neutering status of British dogs with anal sac gland carcinoma.
abstract: This study details the breed, gender and neutering status of a large cohort of British canine patients suffering from histologically confirmed anal sac gland carcinoma. Estimates of the relative risk for the development of this disease attributable to these factors are calculated. To reduce the impact of sampling errors, cases were selected from veterinary histopathology laboratories rather than referral hospital databases, and multiple estimates of the general British canine population were used. The weaknesses of the statistical assumptions made are discussed. There was no evidence to support a gender predisposition for the development of this condition. English cocker spaniels are significantly over-represented, with a mean relative risk estimate of 7.3. The mean relative risk estimate associated with being neutered was 1.4; the effect of neutering appeared to be more significant in male dogs compared with that in female dogs.
authors.affiliation: Davies Veterinary Specialists, Higham Gobion, Herts, UK. gpolton@vetspecialists.co.uk
authors.forename: G A
authors.initials: GA
authors.lastname: Polton
authors.forename: V
authors.initials: V
authors.lastname: Mowat
authors.forename: H C
authors.initials: HC
authors.lastname: Lee
authors.forename: K A
authors.initials: KA
authors.lastname: McKee
authors.forename: T J
authors.initials: TJ
authors.lastname: Scase