Hematologic manifestation of avian influenza patients in hasan sadikin hospital.
OBJECTIVE
To investigate the hematologic manifestation and the relationship of the abnormalities with mortality.


METHODS
We examined hematologic data from 10 Avian influenza patients in Hasan Sadikin Hospital Bandung between November 2005 and March 2007.


RESULTS
The mortality rate was 70%. Anemia was found in 30% (3 of 10 patients). Leukopenia was found in 60% (6 of 10 patients. Lymphopenia and neutropenia were found in 50% (4 of 8 patients) and 62.5% (5 of 8 patients). Sixty percent (6 of 10 patients) had thrombocytopenia. Anemia was not correlated with mortality (OR=0.08). Leukopenia, neutropenia and lymphopenia were correlated with mortality (OR=5, OR=8 and OR=12, respectively). Thrombocytopenia was also correlated with mortality (OR=5).


CONCLUSIONS
Leukopenia, neutropenia, lymphopenia and thrombocytopenia were common findings among avian influenza patients in Hasan Sadikin Hospital. Decreased white blood cells and platelets were correlated with mortality.
Oehadian
Amaylia
A
Department of Internal Medicine, Faculty of Medicine, Padjadjaran University - dr. Hasan Sadikin Hospital, Bandung 40161, Indonesia. amaylia_oehadian@yahoo.com
Jusuf
Hadi
H
Pranggono
Emmy
E
Parwati
Ida
I
Setiabudi
Djatnika
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007214:Indonesia / Q000453:epidemiology; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics*; D007251:Influenza, Human / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D007970:Leukopenia / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D055815:Young Adult
D004279:DNA, Viral