Synthesis of deuterated benzyladenine and its application as a surrogate.
Palladium on carbon-ethylenediamine complex [Pd/C(en)] catalyzed deuteration of N(6)-benzyladenine-d(5), which is a plant growth regulator, to introduce 5 deuterium atoms, while use of Pd/C as a catalyst led to a complete removal of N(6)-benzyl group. The corresponding deuterated N(6)-benzyladenine was successfully used as a surrogate compound for the quantitative analysis of residual benzyladenine in crops using LC/MS/MS.
Modutlwa
Nkaelang
N
Department of Organic and Medicinal Chemistry, Laboratory of Organic Chemistry, Gifu Pharmaceutical University, Gifu 502-8585, Japan.
Tada
Hiroyuki
H
Sugahara
Yoshiki
Y
Shiraki
Koichi
K
Hara
Nobuyuki
N
Deyashiki
Yoshihiro
Y
Ando
Takayuki
T
Maegawa
Tomohiro
T
Monguchi
Yasunari
Y
Sajiki
Hironao
H
D001593:Benzyl Compounds; D002853:Chromatography, Liquid; D003903:Deuterium; D007701:Kinetin / Q000032:analysis* / Q000138:chemical synthesis* / Q000737:chemistry; D010937:Plant Growth Regulators / Q000032:analysis* / Q000138:chemical synthesis* / Q000737:chemistry; D011687:Purines; D053719:Tandem Mass Spectrometry
D001593:Benzyl Compounds; D010937:Plant Growth Regulators; D011687:Purines; D003903:Deuterium; C480551:benzylaminopurine; D007701:Kinetin