title: Ultrasonic focusing through the ribs using the DORT method.
abstract: Thermal ablation induced by high intensity focused ultrasound has produced promising clinical results to treat hepatocarcinoma and other liver tumors. However skin burns have been reported due to the high absorption of ultrasonic energy by the ribs. This study proposes a method to produce an acoustic field focusing on a chosen target while sparing the ribs using the decomposition of the time-reversal operator (DORT method). The idea is to apply an excitation weight vector to the transducers array which is orthogonal to the subspace of emissions focusing on the ribs. A linear array of transducers has been used to measure the set of singular vectors associated with a chest phantom, made of three human ribs immersed in water, and to produce the desired acoustic fields. The resulting propagating fields have been measured both in the focal plane and in the plane of the ribs using a needle hydrophone. The ratio of the energies absorbed at the focal point and on the ribs has been enhanced up to 100-fold, as demonstrated by the measured specific absorption rates.
authors.affiliation: Laboratoire Ondes et Acoustique, CNRS UMR 7587, Université Paris VII, Inserm, ESPCI, 10 rue Vauquelin, 75005 Paris, France. brazuzan@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Cochard
authors.forename: C
authors.initials: C
authors.lastname: Prada
authors.forename: J F
authors.initials: JF
authors.lastname: Aubry
authors.forename: M
authors.initials: M
authors.lastname: Fink
mesh_terms: D000042:Absorption; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D012272:Ribs; D013909:Thorax; D013997:Time Factors; D014464:Ultrasonic Therapy / Q000379:methods*