title: Synthesis and characterization of mannosylated oligoribonucleotides.
abstract: Oligoribonucleotide (RNA)-carbohydrate conjugates bearing mono- and divalent mannosides were readily obtained using 3,4-diethoxy-3-cyclobutene-1,2-dione as the linking agent in the presence of trace amount of triethylamine. The glycoconjugates were purified by HPLC and characterized by electrospray mass spectroscopy.
authors.affiliation: Department of Chemistry, Brock University, Catharines, Ontario, Canada L2S 3A1.
authors.forename: Yuyan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Kha
authors.initials: K
authors.lastname: Tram
authors.forename: Hongbin
authors.initials: H
authors.lastname: Yan
mesh_terms: D003713:Dendritic Cells / Q000378:metabolism; D037181:Lectins, C-Type / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D008358:Mannose / Q000737:chemistry* / Q000378:metabolism; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins / Q000378:metabolism; D009843:Oligoribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D011134:Polysaccharides / Q000737:chemistry; D011956:Receptors, Cell Surface / Q000378:metabolism
chemical_list: D037181:Lectins, C-Type; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D009843:Oligoribonucleotides; D011134:Polysaccharides; D011956:Receptors, Cell Surface; D008358:Mannose