title: [Multiple carcinoids in the midgut causing intestinal gangrene--a case report].
abstract: METHODS
  We report the case of multiple midgut carcinoids causing segmental intestinal ischaemia in a 77-year-old man. He was admitted to our hospital because of a 2-month history of postprandial abdominal pain with nausea / vomiting and anaemia. The extensive diagnostic examinations (blood tests, ultrasound, computed tomography, hydro magnetic resonance) did not reveal any pathological findings. The small-bowel capsule endoscopy demonstrated multiple areas of bleeding. A laparotomy showed a local ischaemia of the small bowel, a segmental resection of the jejunum / ileum was performed. There were no signs of occlusion of the mesenteric artery. The pathological examination revealed 8 carcinoids of the midgut (jejunum / ileum). Immune histology demonstrated serotonin-synaptophysin-chromogranin-producing carcinoids. The patient was re-operated because of suspected ongoing mesenteric ischaemia, but no further pathologies were found. The postoperative course was uneventful. A subsequent octreotide scan was negative for metastases.
  
  
  CONCLUSIONS
  Carcinoids may become symptomatic mimicking intestinal ischaemia. Although this coincidence is considered to be typical, it is still a rare event. The diagnosis is often delayed. EVS ("elastic vascular sclerosis") of the mesenteric artery is pathognomonic for these carcinoids but, as our case demonstrates, not mandatory. According to the literature, the stage of the disease corresponds to the extent of the intestinal ischaemia.
authors.affiliation: Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäss- und Kinderchirurgie, Universitätsklinikum Würzburg, Oberdürrbacher Strasse 6, Würzburg, Germany. Graunke_f@chirurgie.uni-wuerzburg.de
authors.forename: F
authors.initials: F
authors.lastname: Graunke
authors.forename: H U
authors.initials: HU
authors.lastname: Völker
authors.forename: A
authors.initials: A
authors.lastname: Larena-Avellaneda
authors.forename: C T
authors.initials: CT
authors.lastname: Germer
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005734:Gangrene; D006471:Gastrointestinal Hemorrhage / Q000473:pathology / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology / Q000601:surgery*; D007082:Ileum / Q000098:blood supply* / Q000473:pathology*; D007511:Ischemia / Q000473:pathology / Q000601:surgery*; D007580:Jejunal Neoplasms / Q000473:pathology / Q000601:surgery*; D007583:Jejunum / Q000098:blood supply* / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D011183:Postoperative Complications / Q000473:pathology / Q000601:surgery; D012086:Reoperation