title: Cytomegalovirus enteritis mimicking Crohn's disease in a lupus nephritis patient: a case report.
abstract: Cytomegalovirus (CMV) infection of the gastrointestinal (GI) tract has been reported in both immunocompetent and, more frequently, in immunocompromised patients. We describe a case of a 19-year-old male who developed CMV infection of the terminal ileum while receiving immunosuppression for lupus nephritis. This was a distinctly unusual site of infection which clinically mimicked Crohn's ileitis. We note that reports of terminal ileal CMV infection have been infrequent. Despite a complicated hospital course, ganciclovir therapy was effective in resolving his symptoms and normalizing his ileal mucosa. This report highlights the importance of accurate histological diagnosis and clinical follow-up of lupus patients with GI symptoms undergoing intense immunosuppression.
authors.affiliation: Department of Nephrology, Westchester Medical Center, Valhalla, NY 10595, USA.
authors.forename: Faisal Nazir
authors.initials: FN
authors.lastname: Khan
authors.forename: Vinod
authors.initials: V
authors.lastname: Prasad
authors.forename: Michael David
authors.initials: MD
authors.lastname: Klein
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003424:Crohn Disease / Q000175:diagnosis; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007079:Ileitis / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D007082:Ileum / Q000821:virology; D008181:Lupus Nephritis / Q000150:complications*; D008297:Male; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir