Neurocognitive diagnosis and cut-off scores of the Screen for Cognitive Impairment in Psychiatry (SCIP-S).
OBJECTIVE
To demonstrate the ability of the Screen for Cognitive Impairment in Psychiatry (SCIP-S) to discriminate between cognitively-impaired individuals and those with adequate functioning in a sample of schizophrenic and bipolar patients, as well as in a control group.


METHODS
The SCIP-S, together with a full neuropsychological battery, was administered to three groups: patients with schizophrenia, patients diagnosed with bipolar disorder I, and controls. The battery scores were used to perform a standardization with respect to the control group and this served to determine the comparison groups (cognitively impaired versus unimpaired) for each of the subtests of the SCIP-S. A full analysis of decision validity was conducted on the basis of receiver operating characteristic curves (sensitivity and specificity, +LR and -LR, PPV and NPV).


RESULTS
All the subtests yielded adequate values for sensitivity and specificity with the proposed cut-off points, while the total score of the SCIP (<70) was associated with a sensitivity of 87.9 and specificity of 80.6.


CONCLUSIONS
The SCIP-S shows adequate decision validity as a screening tool for cognitive deficit in patients diagnosed with schizophrenia or bipolar disorder.
Rojo
Emilio
E
Department of Psychiatry, Benito Menni CASM, Granollers Hospital General, Granollers, Barcelona, Spain.
Pino
Oscar
O
Guilera
Georgina
G
Gómez-Benito
Juana
J
Purdon
Scot E
SE
Crespo-Facorro
Benedicto
B
Cuesta
Manuel J
MJ
Franco
Manuel
M
Martínez-Arán
Anabel
A
Segarra
Nuria
N
Tabarés-Seisdedos
Rafael
R
Vieta
Eduard
E
Bernardo
Miguel
M
Mesa
Francisco
F
Rejas
Javier
J
D000328:Adult; D001714:Bipolar Disorder / Q000150:complications*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012372:ROC Curve; D012559:Schizophrenia / Q000150:complications*; D012720:Severity of Illness Index