Origin of enantioselectivity in the Jacobsen epoxidation of olefins.
It is proposed that facial selectivity in the Jacobsen epoxidation is determined by electrostatic and steric factors with a two-step pathway involving a carbocationic intermediate.
Kürti
László
L
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Blewett
Megan M
MM
Corey
E J
EJ
D000475:Alkenes / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D000475:Alkenes; D004852:Epoxy Compounds