title: [Analysis of endobronchial aspergillosis in patients without obvious systemic predisposing factors].
abstract: BACKGROUND
  Endobronchial aspergillosis is still an insufficiently recognized concept.
  
  
  METHODS
  Ten patients who did not have obvious predisposing factors and parenchymal fungal infection were analyzed. They were confirmed to have endobronchial Aspergillus by histology and culture, and were classified according to the presence of bronchiectasis, allergic reaction, and asthmatic symptom.
  
  
  RESULTS
  Bronchiectasis was detected in all 10 patients, IgE elevation (>370 IU/ml) in 7, Aspergillus specific IgE-RAST in 8, eosinophilia in 7, and asthmatic symptom in 5. Cases were classified into allergic bronchopulmonary aspergillosis (ABPA) (5 cases), ABPA not fulfilling Rosenberg's criteria (2 cases), and endobronchial aspergilloma (3 cases).
  
  
  CONCLUSIONS
  We proposed classifying endobronchial aspergillosis without obvious systemic predisposing factors into "ABPA", "ABPA without asthma", "ABPA-S (seropositive)", and "Endobronchial aspergilloma". A fifth subtype of endobronchial aspergillosis containing "saprophyte" is warranted.
authors.affiliation: Division of Respiratory Medicine, Department of Medicine, National Defense Medical College.
authors.forename: Hisayuki
authors.initials: H
authors.lastname: Osoreda
authors.forename: Hideo
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Soichiro
authors.initials: S
authors.lastname: Kanoh
authors.forename: Kazuo
authors.initials: K
authors.lastname: Motoyoshi
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ozeki
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055732:Pulmonary Aspergillosis / Q000145:classification / Q000175:diagnosis*