QTL mapping in intercross and backcross populations.
In the past two decades, various statistical approaches have been developed to identify quantitative trait locus with experimental organisms. In this chapter, we introduce several commonly used QTL mapping methods for intercross and backcross populations. Important issues related to QTL mapping, such as threshold and confidence interval calculations are also discussed. We list and describe five public domain QTL software packages commonly used by biologists.
Zou
Fei
F
Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA.
D000818:Animals; D002874:Chromosome Mapping / Q000379:methods*; D003433:Crosses, Genetic; D005828:Genetics, Population / Q000379:methods*; D006801:Humans; D008957:Models, Genetic; D011153:Population / Q000235:genetics; D040641:Quantitative Trait Loci / Q000235:genetics*; D012984:Software