Rapid induction of the immediate early gene c-fos in a chick forebrain system involved in memory.
Previous work has shown that expression of Fos protein in neurons of the intermediate and medial mesopallium (IMM), a memory region in the forebrain of the domestic chick, increases in a learning-related manner after behavioural imprinting. We show here, using in situ hybridisation, that when chicks are trained for 15 min with an imprinting stimulus, expression of c-fos mRNA in the IMM rises to a maximum at or before the end of this training period. The results suggest that the learning-related increase in Fos protein production, which occurs in identifiable neuronal sub-populations in the IMM, reflects events that make an early contribution to learning and/or memory processing.
Suge
Rie
R
Sub-Department of Animal Behaviour, University of Cambridge, Cambridge, UK.
Kato
Hidemasa
H
McCabe
Brian J
BJ
D000161:Acoustic Stimulation; D000818:Animals; D001307:Auditory Perception / Q000502:physiology; D030161:Avian Proteins / Q000378:metabolism; D002645:Chickens; D017781:Genes, Immediate-Early; D016762:Genes, fos; D007173:Imprinting, Psychological / Q000502:physiology*; D017403:In Situ Hybridization; D008568:Memory / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D010775:Photic Stimulation; D016548:Prosencephalon / Q000502:physiology*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D013997:Time Factors; D014796:Visual Perception / Q000502:physiology
D030161:Avian Proteins; D016760:Proto-Oncogene Proteins c-fos; D012333:RNA, Messenger