[A clinical and therapeutic analysis in acute megakaryoblastic leukemia].
OBJECTIVE
to show clinical and therapeutic findings in patients with diagnosis of acute megakaryoblastic leukemia (AML).


METHODS
twenty four patients with diagnosis AML was carried out. Clinical, laboratory survey results and treatment response were studied. Nineteen patients had primary form and five secondary, attended during a period of eight years. The diagnosis was established by a highly clinical suspicious, with immunophenotype cytometry flow or/and bone biopsy with immunohistochemistry study which proves definitely AML.


RESULTS
Fourteen were women, the median age was 43 years, 18 were treated with antineoplasic agents, ten obtained response, six complete and four partial. The response may improve with schemes with high dose of cytosine arabinoside.


CONCLUSIONS
our results with the treatment showed that 27 % patients are alive under maintenance treatment long 18 months. The allogeneic bone marrow transplant seems to be one more option in long term.
Delgado-Lamas
José Luis
JL
Servicio de Hematología, Hospital de Especialidades, Centro Médico Nacional de Occidente, Guadalajara Instituto Mexicano del Seguro Social, Jalisco, Mexico. delgado_lamas2002@hotmail.com
Garcés-Ruiz
Oscar Miguel
OM
Aguilar-López
Lilia Beatriz
LB
Borjas-Gutiérrez
César
C
Flores-Márquez
María Rosa
MR
Luna-Zaizar
Hilda
H
Delgado-Chávez
Raúl
R
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007947:Leukemia, Megakaryoblastic, Acute / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult