title: Thoracic radiotherapy for mediastinal nodal recurrence.
abstract: Radiotherapy has been used to treat loco-regional recurrences located at various intra-thoracic sites, but long-term survival of these patients has been rarely observed. We report herein a lung adenocarcinoma patient with locoregional recurrence, who was successfully treated with high-dose radiotherapy. The patient could survive with no evidence of recurrence 5 years after thoracic irradiation. It is probably safe to administrate high-dose radiotherapy for some loco-regional recurrent patients with favorable prognostic factors such as good PS, no body weight loss. Further studies will be required to define a favorable subset of patients most likely to benefit from an aggressive approach.
authors.affiliation: Division of Respiratory Medicine, University of Tsukuba, Institute of Clinical Medicine Tsubaka-city, Japan.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Kagohashi
authors.forename: Hidetsugu
authors.initials: H
authors.lastname: Nakayama
authors.forename: Kenji
authors.initials: K
authors.lastname: Kagei
authors.forename: Koichi
authors.initials: K
authors.lastname: Kurishima
authors.forename: Hiroichi
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Satoh
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000556:secondary; D000368:Aged; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D011879:Radiotherapy Dosage