Granulocytic sarcoma of the oral cavity in a chronic myeloid leukemia patient: an unusual presentation.
Intraoral granulocytic sarcoma is an unusual manifestation of chronic or acute leukemia. The oral manifestations often involve enlargements of the gingival and mucosal tissue from direct leukemic cell infiltration. Only 38 cases have been reported in scientific literature to date. We present the case of a 47 year-old female who was diagnosed with chronic myeloid leukemia (CML) in December 2006. She was referred to a dentist for further evaluation, revealing generalized gingival overgrowth as well as periodontal, apical disease, and bleeding of the gums. An oral biopsy was performed and histological features revealed immature blast-like cells.
da Silva-Santos
Paulo-Sérgio
PS
Department of Oral Pathology, School of Dentistry, University of São Paulo, São Paulo, Brazil. paulosergiosilvasantos@gmail.com
Silva
Brunno-Santos-de Freitas
BS
Coracin
Fábio-Luiz
FL
Yamamoto
Fernanda-Paula
FP
Pinto-Junior
Décio-dos Santos
DD
Magalhães
Marina G
MG
D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology*; D023981:Sarcoma, Myeloid / Q000209:etiology*