Predictors of medication adherence in high risk youth of color living with HIV.
OBJECTIVE
To test predictors of medication adherence in high-risk racial or ethnic minority youth living with HIV (YLH) using a conceptual model of social cognitive predictors including a continuous measure of motivational readiness.


METHODS
Youth were participants in a multi-site clinical trial examining the efficacy of a motivational intervention. Racial-minority YLH (primarily African American) who were prescribed antiretroviral medication were included (N = 104). Data were collected using computer-assisted personal interviewing method via an Internet-based application and questionnaires.


RESULTS
Using path analysis with bootstrapping, most youth reported suboptimal adherence, which predicted higher viral load. Higher motivational readiness predicted optimal adherence, and higher social support predicted readiness. Decisional balance was indirectly related to adherence.


CONCLUSIONS
The model provided a plausible framework for understanding adherence in this population. Culturally competent interventions focused on readiness and social support may be helpful for improving adherence in YLH.
Macdonell
Karen E
KE
Wayne State University, Pediatric Prevention Research Center, Hutzel Building Suite w534, 4707 St. Antoine, Detroit, MI 48201, USA. kkolmodin@med.wayne.edu
Naar-King
Sylvie
S
Murphy
Debra A
DA
Parsons
Jeffrey T
JT
Harper
Gary W
GW
D000293:Adolescent; D001741:Black or African American / Q000523:psychology; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D006679:HIV Seropositivity / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D009042:Motivation; D012944:Social Support; D011795:Surveys and Questionnaires; D019562:Viral Load; D055815:Young Adult
D044966:Anti-Retroviral Agents