title: Hereditary prothrombin deficiency.
abstract: Hereditary prothrombin deficiency is one of the rare congenital coagulation defects. We report a case of 4 months old child who initially presented at 11/2 month of age with high-grade fever, generalized convulsions and brownish aspirate through nasogastric tube, diagnosed and managed as meningitis and sepsis. He was readmitted at 4 months of age with bruises over legs. Coagulation profile was suggestive of common pathway defect. Further evaluation revealed absent prothrombin level while other factors were within normal limits.
authors.affiliation: Department of Pediatrics, Civil Hospital, Karachi.
authors.forename: Muzamil Shabana
authors.initials: MS
authors.lastname: Ejaz
authors.forename: Nazia
authors.initials: N
authors.lastname: Latif
authors.forename: Ashraf
authors.initials: A
authors.lastname: Memon
mesh_terms: D006801:Humans; D007020:Hypoprothrombinemias / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D007223:Infant; D008297:Male