Diffusion and signaling revisited.
In this issue of Immunity, Andrews et al. (2009) used single-molecule fluorescence microscopy to demonstrate that the IgE receptor FcepsilonRI in the plasma membrane can signal in a mobile state.
Varma
Rajat
R
Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 Center Drive, Bethesda, MD 20892, USA. varmarajat@niaid.nih.gov
D000941:Antigens / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D055503:Protein Multimerization; D021381:Protein Transport; D017455:Receptors, IgE / Q000276:immunology* / Q000378:metabolism; D015398:Signal Transduction
D000941:Antigens; D017455:Receptors, IgE; D007073:Immunoglobulin E