[Allergic bronchopulmonary mycosis induced by Schizophyllum commune--case report and review of the literature].
A 55-year-old man was admitted to our hospital because of pyrexia, cough and sputum. He suffered from bronchial asthma. Chest X-ray showed infiltrates in the left upper and right lower lung fields. Chest CT scans showed mucoid impaction and consolidation predominantly in the left upper lobe. Laboratory tests showed peripheral eosinophilia, elevated level of serum IgE, and the increased eosinophils in his sputum. Schizophyllum commune was isolated from the bronchoscopically-removed mucous plug. A diagnosis of allergic bronchopulmonary mycosis (ABPM) due to S. commune was made. Simultaneous daily administration of 400 mg itraconazole (ITCZ) and corticosteroid (prednisolone; 30 mg daily) provided sufficient improvement. However recurrence was recognized on chest CT scan findings one year later. There are not enough case reports concerning S. commune-induced ABPM to establish a therapeutic approach to the condition.
Amemiya
Yuka
Y
Department of Internal Medicine 2, Oita University Faculty of Medicine.
Shirai
Ryo
R
Tokimatsu
Issei
I
Oka
Hiroaki
H
Iwata
Atsuko
A
Otani
Satoshi
S
Umeki
Kenji
K
Sakashita
Hiroyuki
H
Ishii
Hiroshi
H
Gendo
Yoshiko
Y
Kishi
Kenji
K
Hiramatsu
Kazufumi
K
Kadota
Jun-ichi
J
D006801:Humans; D008172:Lung Diseases, Fungal / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012567:Schizophyllum / Q000276:immunology*