Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora.
Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.
Ferheen
Sadia
S
Pharmaceutical Research Centre, PCSIR Laboratories Complex, Karachi 75280, Pakistan.
Afza
Nighat
N
Malik
Abdul
A
Iqbal
Lubna
L
Azam Rasool
Muhammad
M
Irfan Ali
Muhammad
M
Bakhsh Tareen
Rasool
R
D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018514:Plant Structures / Q000737:chemistry; D014510:Urease / Q000037:antagonists & inhibitors
D000975:Antioxidants; D044950:Flavanones; D005960:Glucosides; D010936:Plant Extracts; C547298:galinsoside A; C547299:galinsoside B; D014510:Urease