title: A systematic approach to the investigation and diagnosis of a unilateral pleural effusion.
abstract: Fluid in the pleural space is a common sequela of a wide range of diseases which may be pulmonary, pleural or extrapulmonary. As the differential diagnosis is wide, a systematic approach to investigation and diagnosis is recommended. This review highlights the important features and recommendations for the investigation of a unilateral pleural effusion, a common condition encountered by the general physician. The aim of this study was to assist with a speedy diagnosis of the underlying pathology, using appropriate investigative techniques, while minimising the use of invasive procedures.
authors.affiliation: Department of Respiratory Medicine, Northern General Hospital, Sheffield S5 7AU, UK. e.mcgrath@sheffield.ac.uk
authors.forename: E E
authors.initials: EE
authors.lastname: McGrath
authors.forename: Z
authors.initials: Z
authors.lastname: Blades
authors.forename: J
authors.initials: J
authors.lastname: Needham
authors.forename: P B
authors.initials: PB
authors.lastname: Anderson
mesh_terms: D001706:Biopsy / Q000379:methods; D001999:Bronchoscopy; D002913:Chyle / Q000737:chemistry; D002916:Chylothorax / Q000175:diagnosis; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D005122:Exudates and Transudates / Q000737:chemistry; D006801:Humans; D008487:Medical History Taking; D010808:Physical Examination; D010994:Pleura / Q000473:pathology; D010996:Pleural Effusion / Q000175:diagnosis* / Q000209:etiology; D012017:Referral and Consultation