Stereotactic radiotherapy for vestibular schwannoma.
Vestibular schwannomas are benign tumors of the Schwann cells of the eighth (VIII) cranial nerve. Precision radiotherapy techniques used to manage these tumors include stereotactic radiotherapy (SRT), which can be delivered with either a conventional or hypofractionated regimen. The radio-biologic rationale and reported clinical outcomes of patients treated with SRT are reviewed.
Sweeney
Patrick
P
Illinois Gamma Knife Center, Alexian Neurosciences Institute, Alexian Brothers Medical Center, 800 Biesterfield Road, Elk Grove Village, IL 60007, USA. psweeney@chicagocancer.org
Yajnik
Santosh
S
Hartsell
William
W
Bovis
George
G
Venkatesan
Jagannath
J
D000818:Animals; D001707:Biopsy, Needle; D019583:Dose Fractionation, Radiation; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D051379:Mice; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology*; D009367:Neoplasm Staging; D009464:Neuroma, Acoustic / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011379:Prognosis; D011832:Radiation Injuries / Q000517:prevention & control*; D011853:Radiobiology; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods; D018570:Risk Assessment; D013238:Stereotaxic Techniques; D016019:Survival Analysis; D016896:Treatment Outcome