title: [Pedigree analysis and prosthodontic treatment of patients with dentinogenesis imperfecta type II].
abstract: OBJECTIVE
  To study the heritable character and explore the prosthodontic treatment of opalescent dentin, also known as dentinogenesis imperfecta type II(DGI-II).
  
  
  METHODS
  Pedigree analysis was performed in the family members of patients with DGI-II found in Shanghai. The proband was treated with ceramometal restorations and investigated the treatment status of the DGI-II affected individuals in the family.
  
  
  RESULTS
  Five sequential generations with DGI-II were found in this family. The prevalence of later generation was approximately 50%. The rate of prosthodontic treatment was 90% nearly, including ceramometal restorations in the most of the patients and removable partial dentures in the others. The esthetic and mastication functions of the patients were good after treatment.
  
  
  CONCLUSIONS
  DGI-II showed a autosomal dominant pattern of inheritance. Ceramaometal restorations can prevent the affected teeth from abrasive and fracture, and also can help rehabilitate the esthetic and mastication functions of the teeth.
authors.affiliation: Department of Prosthodontics, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China. gan_honggh@126.com
authors.forename: Hong
authors.initials: H
authors.lastname: Gan
authors.forename: Xiu-yin
authors.initials: XY
authors.lastname: Zhang
authors.forename: Xiao-cen
authors.initials: XC
authors.lastname: Xu
mesh_terms: D002681:China; D003811:Dentinogenesis Imperfecta; D016326:Extracellular Matrix Proteins; D006801:Humans; D010375:Pedigree; D010750:Phosphoproteins; D011476:Prosthodontics
chemical_list: D016326:Extracellular Matrix Proteins; D010750:Phosphoproteins