title: Pharmacological profile and clinical efficacy of minodronic acid hydrate as a new therapeutic agent for osteoporosis.
authors.affiliation: mak.tanaka@ono.co.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Tanaka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mori
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Shimizu
authors.lastname: Toshiyuki
authors.lastname: Matsuoka
authors.forename: Hajime
authors.initials: H
authors.lastname: Yamamotoya
authors.forename: Toshiomi
authors.initials: T
authors.lastname: Minamide
authors.forename: Masamichi
authors.initials: M
authors.lastname: Mori
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Nozaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Usui
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Shimokawa
authors.forename: Hiromi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Koji
authors.initials: K
authors.lastname: Aoyama
authors.forename: Aishi
authors.initials: A
authors.lastname: Kimoto
authors.forename: Masao
authors.initials: M
authors.lastname: Sasamata
authors.forename: Keiji
authors.initials: K
authors.lastname: Miyata
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use*; D016723:Bone Remodeling / Q000187:drug effects; D001862:Bone Resorption / Q000188:drug therapy; D002986:Clinical Trials as Topic; D004164:Diphosphonates / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use*; D019204:GTP-Binding Proteins / Q000378:metabolism; D051228:Geranyltranstransferase / Q000037:antagonists & inhibitors; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use*; D008798:Mevalonic Acid / Q000378:metabolism; D010024:Osteoporosis / Q000188:drug therapy*; D016103:Spinal Fractures / Q000517:prevention & control
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; C087958:YM 529; D051228:Geranyltranstransferase; D019204:GTP-Binding Proteins; D008798:Mevalonic Acid