title: Stereotactic body radiosurgery for pelvic relapse of gynecologic malignancies.
abstract: Clinical management of pelvic relapses from gynecologic malignancies remains challenging. Bulky pelvic relapses often lead to symptomatic cancer-related complications and poor clinical outcomes. Options may be limited by prior surgical, chemotherapeutic, and radiation treatment. Stereotactic body radiosurgery is a novel treatment modality which allows high radiation dose delivery in a non-coplanar fashion with sub-millimeter precision utilizing a linear accelerator mounted on a robotic arm. This study details our clinical experience with stereotactic body radiosurgery for treatment of patients with pelvic relapses of gynecologic malignancies after prior pelvic radiation.
authors.affiliation: Department of Radiation Oncology, Hospital of Cleveland MAILSTOP: LTR 6068 Case Medical Center and Case Western Reserve University Cleveland, OH 44106, USA. charles.kunos@uhhospitals.org
authors.forename: Charles
authors.initials: C
authors.lastname: Kunos
authors.forename: William
authors.initials: W
authors.lastname: Chen
authors.forename: Robert
authors.initials: R
authors.lastname: DeBernardo
authors.forename: Steven
authors.initials: S
authors.lastname: Waggoner
authors.forename: James
authors.initials: J
authors.lastname: Brindle
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jordanna
authors.initials: J
authors.lastname: Williams
authors.forename: Douglas
authors.initials: D
authors.lastname: Einstein
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery*; D011379:Prognosis; D016634:Radiosurgery; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*