title: Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues.
abstract: PDMS-based microfluidic devices combined with lanthanide-based immunocomplexes have been successfully tested for the multiplex detection of biomarkers on cancerous tissues, revealing an enhanced sensitivity compared to classical organic dyes.
authors.affiliation: Laboratory of Lanthanide Supramolecular Chemistry (LCSL), Ecole Polytechnique Fédérale de Lausanne, BCH 1404, 1015 Lausanne, Switzerland.
authors.forename: Bo
authors.initials: B
authors.lastname: Song
authors.forename: Venkataragavalu
authors.initials: V
authors.lastname: Sivagnanam
authors.forename: Caroline D B
authors.initials: CD
authors.lastname: Vandevyver
authors.forename: Ilkka
authors.initials: I
authors.lastname: Hemmilä
authors.forename: Hans-Anton
authors.initials: HA
authors.lastname: Lehr
authors.forename: Martin A M
authors.initials: MA
authors.lastname: Gijs
authors.forename: Jean-Claude G
authors.initials: JC
authors.lastname: Bünzli
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis* / Q000276:immunology; D045744:Cell Line, Tumor; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D006801:Humans; D007118:Immunoassay; D056656:Lab-On-A-Chip Devices; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008163:Luminescent Measurements; D009369:Neoplasms / Q000473:pathology*; D013997:Time Factors
chemical_list: D014408:Biomarkers, Tumor; D004129:Dimethylpolysiloxanes; D028581:Lanthanoid Series Elements; C013830:baysilon