title: Mask-like metastasis: report of 2 cases of 4 eyelid metastases and review of the literature.
abstract: Bilateral periorbital edema and swelling are frequent in clinical practice and are commonly attributed to orbital contact dermatitis due to different drugs and cosmetic products. However, when there is a background of a solid cancer, the possibility of eyelid metastasis should be also considered. Metastases to the eyelids are rare, and in most cases, these lesions are unilateral. Because only a few cases of bilateral involvement have been reported in the literature, clinical and morphological data of this variant are under recognized. We report the clinical and histopathological characteristics of 2 patients with 4 eyelid metastasis and review the previous cases reported in the literature.
authors.affiliation: Servicio de Dermatología, Fundación Instituto Valenciano de Oncología, Valencia, España. antmarto@hotmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Martorell-Calatayud
authors.forename: Celia
authors.initials: C
authors.lastname: Requena
authors.forename: José Luis
authors.initials: JL
authors.lastname: Díaz-Recuero
authors.forename: Rosario
authors.initials: R
authors.lastname: Haro
authors.forename: José Luis
authors.initials: JL
authors.lastname: Sarasa
authors.forename: Onofre
authors.initials: O
authors.lastname: Sanmartín
authors.forename: Rafael
authors.initials: R
authors.lastname: Botella-Estrada
authors.forename: Mar Burgués
authors.initials: MB
authors.lastname: Calderón
authors.forename: Carlos Guillén
authors.initials: CG
authors.lastname: Barona
authors.forename: Luis
authors.initials: L
authors.lastname: Requena
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology*; D018275:Carcinoma, Lobular / Q000188:drug therapy / Q000556:secondary*; D004487:Edema / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism; D005142:Eyelid Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor