title: Langerhans cell histiocytosis revealed by painful hip: a case report.
abstract: Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.
authors.affiliation: Paediatric Department, Fattouma Bourguiba Hospital, Monastir, Tunisia. hamami_sabeur@yahoo.fr
authors.forename: Hammami
authors.initials: H
authors.lastname: Sabeur
authors.forename: B Meriem
authors.initials: BM
authors.lastname: Chebil
authors.forename: B Ameur
authors.initials: BA
authors.lastname: Karim
authors.forename: Hadded
authors.initials: H
authors.lastname: Samir
authors.forename: Ghédira
authors.initials: G
authors.lastname: Leila
authors.forename: Hafsa
authors.initials: H
authors.lastname: Chiraz
authors.forename: Chouchane
authors.initials: C
authors.lastname: Slaheddine
authors.forename: Guediche Mohamed
authors.initials: GM
authors.lastname: Néji
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D007839:Functional Laterality; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D010026:Osteosclerosis / Q000000981:diagnostic imaging; D010031:Otitis / Q000175:diagnosis; D010146:Pain / Q000209:etiology; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones