title: [Subluxation of hydrophilic acrylate intraocular lenses due to massive capsular fibrosis].
abstract: BACKGROUND
  Compared with other biomaterials, hydrophilic acrylate provides better uveal biocompatibility, lower adhesion rates of bacteria and silicone oil, and less glare. Because of reduced capsular biocompatibility, increased fibrosis may initiate dislocation of the intraocular lens (IOL).
  
  
  METHODS
  In six eyes of four patients, enhanced fibroses led to IOL dislocation, leading to an IOL exchange an average of 40 weeks after implantation of the same hydrophilic acrylate lens type.
  
  
  CONCLUSIONS
  Predisposing factors were found in 90% of all reported cases of IOL dislocation in the literature, but not in the cases described here. The lens type that was implanted was unable to adapt to the massive fibrosis induced by its hydrophilic biomaterial.
  
  
  CONCLUSIONS
  The pattern of lens opacification should receive attention when one is choosing an IOL type. Eyes showing pseudoexfoliation syndrome as well as post-uveitis eyes might require a hydrophilic IOL for less cellular reaction, whereas a posterior subcapsular cataract might need a hydrophobic IOL to prevent a massive capsular fibrosis. In the case of increased capsular contraction, unreflected YAG laser capsulotomy may result in IOL subluxation when the lens design cannot handle capsule shrinkage, as demonstrated here.
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Homburg/Saar, Kirrberger Strasse, 66421, Homburg/Saar, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Kramer
authors.forename: A C
authors.initials: AC
authors.lastname: Schröder
authors.forename: K
authors.initials: K
authors.lastname: Brückner
authors.forename: C
authors.initials: C
authors.lastname: Jonescu-Cuypers
authors.forename: B
authors.initials: B
authors.lastname: Seitz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005355:Fibrosis / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007906:Lens Subluxation / Q000175:diagnosis* / Q000209:etiology*; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male