[Analysis of endobronchial aspergillosis in patients without obvious systemic predisposing factors].
BACKGROUND
Endobronchial aspergillosis is still an insufficiently recognized concept.


METHODS
Ten patients who did not have obvious predisposing factors and parenchymal fungal infection were analyzed. They were confirmed to have endobronchial Aspergillus by histology and culture, and were classified according to the presence of bronchiectasis, allergic reaction, and asthmatic symptom.


RESULTS
Bronchiectasis was detected in all 10 patients, IgE elevation (>370 IU/ml) in 7, Aspergillus specific IgE-RAST in 8, eosinophilia in 7, and asthmatic symptom in 5. Cases were classified into allergic bronchopulmonary aspergillosis (ABPA) (5 cases), ABPA not fulfilling Rosenberg's criteria (2 cases), and endobronchial aspergilloma (3 cases).


CONCLUSIONS
We proposed classifying endobronchial aspergillosis without obvious systemic predisposing factors into "ABPA", "ABPA without asthma", "ABPA-S (seropositive)", and "Endobronchial aspergilloma". A fifth subtype of endobronchial aspergillosis containing "saprophyte" is warranted.
Osoreda
Hisayuki
H
Division of Respiratory Medicine, Department of Medicine, National Defense Medical College.
Kobayashi
Hideo
H
Kanoh
Soichiro
S
Motoyoshi
Kazuo
K
Ozeki
Yuichi
Y
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055732:Pulmonary Aspergillosis / Q000145:classification / Q000175:diagnosis*