Simple chiral chain dienes as ligands for Rh(I)-catalyzed conjugated additions.
This paper describes that a simple and readily available chain diene (3R,4R)-hexa-1,5-diene-3,4-diol (L1) was successfully utilized as a novel steering ligand for Rh(I)-catalyzed asymmetric conjugated additions. Encouraging yields and ee's have been achieved, which may provide a new and practical direction for designing chiral diene ligands in the future.
Hu
Xichao
X
Beijing National Laboratory of Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Zhuang
Minyang
M
Cao
Ziping
Z
Du
Haifeng
H