title: Impact of drug eluting stents on target vessel revascularization. A report from the Western Denmark heart registry from 2000 to 2004.
abstract: BACKGROUND
  Limited information is available on target lesion revascularization (TLR) after percutaneous coronary intervention (PCI) in unselected patients at the beginning of the drug eluting stent (DES) era.
  
  
  RESULTS
  From January 2000 to September 2004 data from all PCI procedures in Western Denmark were recorded in the Western Danish Heart Registry. A total of 24,701 lesions were treated in 15,542 patients. Lesion length, stent length, frequency of complex lesions and age increased from 2000 to 2004. The use of DES increased from 0% in 2000, 2001, 2002 to 34% in 2003 and 54.0% in 2004 of all stents used. The clinical driven TLR declined from 9.4% in 2000 to 5.4% in 2004. The use of DES (OR 0.60; 95% CI 0.39-0.92, p=0.018) and procedure year (OR 0.89; 95% CI 0.83-0.97, p=0.008) and restenotic lesion (OR 1.51; 95% CI 1.18-1.93, p=0.001) were independent predictors of a TLR. Similar TLR rates were observed in diabetics (7.7%) and non-diabetic (7.0), p=NS.
  
  
  CONCLUSIONS
  In unselected PCI patients the TLR rate declined from 2000 to 2004. The use of DES was an independent predictor of TLR.
authors.affiliation: Department of Cardiology Odense University Hospital, Odense, Denmark.
authors.forename: Lisette Okkels
authors.initials: LO
authors.lastname: Jensen
authors.forename: Michael
authors.initials: M
authors.lastname: Maeng
authors.forename: Per
authors.initials: P
authors.lastname: Thayssen
authors.forename: Jens Flensted
authors.initials: JF
authors.lastname: Lassen
authors.forename: Hans Erik
authors.initials: HE
authors.lastname: Bøtker
authors.forename: Klaus
authors.initials: K
authors.lastname: Rasmussen
authors.forename: Leif
authors.initials: L
authors.lastname: Thuesen