title: Floating-Harbor syndrome and intramedullary spinal cord ganglioglioma: case report and observations from the literature.
abstract: We report on a 5-year-old male with expressive language delay, developmental delay, short stature, and facial anomalies consistent with Floating-Harbor syndrome (FHS). In addition, he developed an intramedullary ganglioglioma. This is the first reported case of a tumor associated with FHS, and may represent an as yet undefined genetic link between spinal cord tumors and FHS, adding this syndrome to the growing list of disorders with a predisposition for tumor development.
authors.affiliation: Department of Pediatrics, University of California at Davis, Sacramento, California 95817, USA.
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Nelson
authors.forename: Michelle
authors.initials: M
authors.lastname: McNamara
authors.forename: William
authors.initials: W
authors.lastname: Ellis
authors.forename: Rebecca
authors.initials: R
authors.lastname: Stein-Wexler
authors.forename: Billur
authors.initials: B
authors.lastname: Moghaddam
authors.forename: Theodore
authors.initials: T
authors.lastname: Zwerdling
mesh_terms: D002675:Child, Preschool; D019465:Craniofacial Abnormalities / Q000150:complications* / Q000175:diagnosis; D002658:Developmental Disabilities / Q000150:complications* / Q000175:diagnosis; D018303:Ganglioglioma / Q000150:complications* / Q000175:diagnosis; D006130:Growth Disorders / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007805:Language Development Disorders / Q000150:complications / Q000175:diagnosis; D008297:Male; D013120:Spinal Cord Neoplasms / Q000150:complications* / Q000175:diagnosis; D013577:Syndrome