A simple and rapid protocol for the synthesis of phenacyl derivatives using macroporous polymer-supported reagents.
This article describes the use of Amberlite IRA-910 with different counter ions as excellent polymer-supported reagents in nucleophilic substitution reactions. The versatility of this protocol allowed the synthesis of a diversified library of phenacyl derivatives with high yields. The polymeric reagents can be reloaded several times with no loss of their efficiency.
Kiasat
Ali R
AR
Chemistry Department, College of Science, Shahid Chamran University, Ahvaz, 61357-4-3169, Iran. akiasat@scu.ac.ir
Sayyahi
Soheil
S
D000098:Acetophenones / Q000138:chemical synthesis* / Q000737:chemistry; D017605:Bromine Compounds / Q000138:chemical synthesis / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D012117:Resins, Synthetic / Q000737:chemistry*; D013861:Thiocyanates / Q000737:chemistry*
D000098:Acetophenones; D017605:Bromine Compounds; D007659:Ketones; D012117:Resins, Synthetic; D013861:Thiocyanates; C046797:amberlite