title: Left ventricular geometric patterns in normotensive type 2 diabetic patients in Nigeria: an echocardiographic study.
abstract: Left ventricular hypertrophy has been linked with diabetes mellitus and abnormal glucose tolerance in several studies. Most previous studies have been carried out in the western world with dearth of data in native Africans. A total of 122 type 2 diabetic patients with a mean age of 55.0+/-8.5 years and another 90 normal patients with a mean age of 55.4+/-8.7 years were recruited for the study. Two-dimensional guided M-mode echocardiography was performed on each patient. In the diabetic patients, 49.2% had normal geometry, 23.0% had concentric hypertrophy, 13.0% had concentric remodeling, and 14.8% had eccentric hypertrophy. In the control group, 72.2% had normal geometry, 4.4% had concentric hypertrophy, 11.2% had concentric remodeling, and 12.2% had eccentric hypertrophy. In a multiple regression analysis, there was significant difference in the geometric pattern of the diabetics and controls (chi(2)=11.09, P<.001). Diabetes mellitus is independently associated with left ventricular structural changes in Nigerian diabetics.
authors.affiliation: Division of Cardiovascular Medicine, Department of Medicine, University College Hospital, Ibadan, Nigeria. dikeojji@yahoo.co.uk
authors.forename: Dike B
authors.initials: DB
authors.lastname: Ojji
authors.forename: Adewole A
authors.initials: AA
authors.lastname: Adebiyi
authors.forename: Olulola O
authors.initials: OO
authors.lastname: Oladapo
authors.forename: Jokotade A
authors.initials: JA
authors.lastname: Adeleye
authors.forename: Akinyemi
authors.initials: A
authors.lastname: Aje
authors.forename: Okechukwu S
authors.initials: OS
authors.lastname: Ogah
authors.forename: Adedeji K
authors.initials: AK
authors.lastname: Adebayo
authors.forename: Ayodele O
authors.initials: AO
authors.lastname: Falase
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000000981:diagnostic imaging; D020257:Ventricular Remodeling