title: Point/Counterpoint. The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery.
authors.affiliation: Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA. kirkp001@mc.duke.edu
authors.forename: John P
authors.initials: JP
authors.lastname: Kirkpatrick
authors.forename: David J
authors.initials: DJ
authors.lastname: Brenner
authors.forename: Colin G
authors.initials: CG
authors.lastname: Orton
mesh_terms: D019583:Dose Fractionation, Radiation; D006801:Humans; D016014:Linear Models; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism; D011829:Radiation Dosage; D016634:Radiosurgery / Q000379:methods*
chemical_list: D010100:Oxygen