title: Prognostic role of tumor-head volume ratio in fetal sacrococcygeal teratoma.
abstract: OBJECTIVE
  To evaluate the ability of a tumor-head volume ratio to predict outcome and incidence of hydrops in fetuses with sacrococcygeal teratoma.
  
  
  METHODS
  Seventy-one sonograms were reviewed retrospectively from 28 fetuses with sacrococcygeal teratoma managed in our institution. Head volume (HV) and total tumor volume were calculated from sonograms. Amount of cystic tumor was estimated to determine solid tumor volume (STV) for the STV/HV ratio.
  
  
  RESULTS
  Twenty percent of sonograms with STV/HV <1 and 97.3% with STV/HV >1 were associated with 1 or more abnormal sonographic signs (p = 0.000). Overall mortality was 11/27 (41%). There was no mortality in fetuses with a ratio of <1, while 11/18 (61%) of fetuses with ratio >1 died (p = 0.003).
  
  
  CONCLUSIONS
  The STV/HV ratio may be used to identify fetuses with a high risk of a poor outcome due to high-output cardiac failure and hydrops, and may help guide management.
authors.affiliation: Department of Surgery, National Cheng Kung University Hospital, Tainan, Taiwan, ROC.
authors.forename: Edgar D
authors.initials: ED
authors.lastname: Sy
authors.forename: Roy A
authors.initials: RA
authors.lastname: Filly
authors.forename: Mei-Leng
authors.initials: ML
authors.lastname: Cheong
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Clifton
authors.forename: Raul A
authors.initials: RA
authors.lastname: Cortes
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Ohashi
authors.forename: Katsunari
authors.initials: K
authors.lastname: Takifuji
authors.forename: Denise Estefan
authors.initials: DE
authors.lastname: Ventura
authors.forename: Erich J
authors.initials: EJ
authors.lastname: Grethel
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Wagner
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Gress
authors.forename: Robert H
authors.initials: RH
authors.lastname: Ball
authors.forename: Hanmin
authors.initials: H
authors.lastname: Lee
authors.forename: Michael R
authors.initials: MR
authors.lastname: Harrison
mesh_terms: D015331:Cohort Studies; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000453:epidemiology; D015994:Incidence; D011379:Prognosis; D012445:Sacrococcygeal Region / Q000000981:diagnostic imaging / Q000473:pathology*; D013724:Teratoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D016216:Ultrasonography, Prenatal