title: Cascade synthesis of (E)-2-alkylidenecyclobutanols.
abstract: A facile, one-pot reaction cascade condenses 1,1,1-trichloroalkanes with alpha,beta-unsaturated ketones to unexpectedly furnish moderate to good yields of (E)-2-alkylidenecyclobutanols.
authors.affiliation: Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. j.falck@utsouthwestern.edu
authors.forename: J R
authors.initials: JR
authors.lastname: Falck
authors.forename: Anish
authors.initials: A
authors.lastname: Bandyopadhyay
authors.forename: Narender
authors.initials: N
authors.lastname: Puli
authors.forename: Abhijit
authors.initials: A
authors.lastname: Kundu
authors.forename: L Manmohan
authors.initials: LM
authors.lastname: Reddy
authors.forename: Deb K
authors.initials: DK
authors.lastname: Barma
authors.forename: Anyu
authors.initials: A
authors.lastname: He
authors.forename: Hongming
authors.initials: H
authors.lastname: Zhang
authors.forename: Dhurke
authors.initials: D
authors.lastname: Kashinath
authors.forename: Rachid
authors.initials: R
authors.lastname: Baati
mesh_terms: D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D003503:Cyclobutanes; D007659:Ketones; C538814:cyclobutanol