title: [Fasting leptinemia in eutrophic children and adolescents].
abstract: OBJECTIVE
  To determine, in a group of eutrophic children and adolescents, the values of fasting leptinemia and its correlation with age and body mass index.
  
  
  METHODS
  A cross-sectional study conducted in two public schools in Ribeirao Preto, Brazil. Anthropometric measurements and venous blood samples were obtained for determination of fasting leptinemia of 448 eutrophic and medium mature children and adolescents, of both genders, aged between 7 and 17.9 years. Using the Mann-Whitney test, comparisons were made between the concentrations obtained for boys and girls in each age group. Subsequently, using the Kruskal-Wallis test, values were compared in each age group and, using the Spearman correlation test, the correlations between fasting leptinemia and age and between fasting leptinemia and the z-scores of body mass index were assessed.
  
  
  RESULTS
  Fasting leptinemia values differed between boys and girls in all age groups and it was higher for girls. Among boys, the values of leptinemia did not show statistically significant variation; among girls, there was variability, with gradual increase according to age group. The correlation study showed positive correlation between leptinemia and z-scores of body mass index in both genders and between leptinemia and age only for girls.
  
  
  CONCLUSIONS
  The data show the necessity of establishing reference curves for fasting leptinemia taking into account gender age and body mass index.
authors.affiliation: Centro de Estudos em Saúde e Nutrição Infanto-Juvenil (CESNI) da Universidade de Ribeirão Preto, S. Paulo, SP, Brazil.
authors.forename: Carlos Alberto Nogueira de
authors.initials: CA
authors.lastname: Almeida
authors.forename: Adriana Pelegrino Pinho
authors.initials: AP
authors.lastname: Ramos
authors.forename: Iguatemy Lourenço
authors.initials: IL
authors.lastname: Brunetti
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Pepato
authors.forename: Rubens Garcia
authors.initials: RG
authors.lastname: Ricco
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000367:Age Factors; D015992:Body Mass Index; D002648:Child; D003430:Cross-Sectional Studies; D005215:Fasting / Q000097:blood*; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D017678:Sex Distribution; D018709:Statistics, Nonparametric
chemical_list: D020738:Leptin