Sclerosing haemangioma with a predominant sclerotic pattern: an unusual pulmonary lesion which can be misdiagnosed.
OBJECTIVE
An unusual sclerosing haemangioma of the lung with a predominant sclerotic pattern is described.


CONCLUSIONS
The patient was a 51-year-old male, presenting with a well-circumscribed nodule, 0,6 cm in diameter, located in the lower lobe of the left lung. He is alive and well 9 years after surgical excision of the nodule. Microscopically, the lesion was well demarcated and mostly composed of sclerotic tissue, with numerous irregular entrapped alveolar spaces The characteristic bland, round cells with abundant pale cytoplasm, immunohistochemically positive for TTF-1 and negative for cytokeratin, were limited to small clusters embedded in the stroma at the periphery of the nodule. The most important differential diagnostic considerations of the sclerotic variant of pulmonary sclerosing haemangioma are briefly discussed.
Cavazza
Alberto
A
Unità Operativa di Anatomia Patologica, Ospedale S. Maria Nuova, Viale Risorgimento 80, 42100 Reggio Emilia, Italy. cavazza.alberto@asmn.re.it
Pellegrino
Sandra
S
Putrino
Innocenza
I
De Marco
Loredana
L
Rossi
Giulio
G
D000230:Adenocarcinoma / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000032:analysis; D004268:DNA-Binding Proteins / Q000032:analysis; D003937:Diagnosis, Differential; D006391:Hemangioma / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D047868:Pulmonary Sclerosing Hemangioma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014157:Transcription Factors
D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; C504003:TTF1 protein, human; D014157:Transcription Factors