title: [Vasomotor innervation of the human pia mater in arterial hypertension].
abstract: Materials of forensic-medical autopsies of men, aged 18-44 year, who died from trauma, have been studied. Arteries of the pia mater have been taken from 26 men with arterial hypertension (AH), stages I-III, and 12 men without AH. Histochemical methods have been used to study the structure of nerve plexus of medial brain artery branches of different diameters. In AH, there were changes of the nerve plexus structure in brain arterial branches, the intensity of which was related to the vessel diameter and disease stage; the decrease of density of periadventicial adrenergic nerve plexus compared to controls, which was most intensive in AH, stage I, and in the vessels of smaller size. The changes in concentration of distinctly seen bulges (varicosities) were more significant compared to those of nervous fibers. The effectiveness of nitrooxidergic innervation was also decreased in large vessels and its structure did not visibly change in small arterial branches. In conclusion, there is a formation of vasomotor innervation dysfunction in AH.
authors.forename: A E
authors.initials: AE
authors.lastname: Kotsiuba
authors.forename: E V
authors.initials: EV
authors.lastname: Babich
authors.forename: V M
authors.initials: VM
authors.lastname: Chertok
mesh_terms: D000293:Adolescent; D000320:Adrenergic Fibers / Q000473:pathology*; D000328:Adult; D002102:Cadaver; D006801:Humans; D006973:Hypertension / Q000473:pathology*; D008297:Male; D020768:Middle Cerebral Artery / Q000294:innervation*; D010841:Pia Mater / Q000473:pathology*; D055815:Young Adult