title: Prospective assessment of overactive bladder symptoms in women who have undergone transvaginal surgery for advanced vaginal wall prolapse: a preliminary report.
abstract: OBJECTIVE
  To evaluate the changes in symptoms of overactive bladder (OAB) on the advanced cystocele after restoration of prolapse using the Perigee system.
  
  
  METHODS
  This prospective clinical study recorded 16 women for the Perigee procedure due to advanced cystocele with OAB symptoms. Prolapse assessment was measured according to the pelvic organ prolapse quantization system. Complete urodynamic examination was performed before and six months after the operation. Subjects were also asked to fill in a questionnaire before and after the operation for a quantitative assay of OAB symptoms. Additional pelvic reconstructive surgeries including the Apogee procedure, retropubic tension-free vaginal tape and posterior colporrhaphy with tension-free vaginal tape were performed concurrently on 10 patients.
  
  
  RESULTS
  Eleven cases were available for data analysis. Results showed significant improvement at points Aa and Ba after the operation. The Perigee procedure could restore the advanced cystocele adequately, with points Aa and Ba almost back to their normal physiological and anatomical positions. However, urodynamics showed two subjects with motor urgency and one with sensory urgency having objective improvement in urge sensation. Questionnaire results of postoperative subjective symptoms revealed a significant improvement with respect to coping, concern and sleep as compared to preoperative symptoms.
  
  
  CONCLUSIONS
  This preliminary report reveals that the Perigee procedure is an efficient and effective surgical approach for the treatment of anterior vaginal wall prolapse. It can also improve the subjective symptoms of OAB.
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung, Taiwan.
authors.forename: Hung-Yen
authors.initials: HY
authors.lastname: Chin
authors.forename: Chi-Hsin
authors.initials: CH
authors.lastname: Chiang
authors.forename: Kuan-Cheng
authors.initials: KC
authors.lastname: Lin
authors.forename: Chin-Jung
authors.initials: CJ
authors.lastname: Wang
authors.forename: Chyi-Long
authors.initials: CL
authors.lastname: Lee
authors.forename: Yung-Kuei
authors.initials: YK
authors.lastname: Soong
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D013526:Surgical Mesh / Q000009:adverse effects; D053201:Urinary Bladder, Overactive / Q000503:physiopathology / Q000601:surgery*; D014554:Urination; D014563:Urodynamics; D014621:Vagina / Q000601:surgery*; D014623:Vaginal Diseases / Q000503:physiopathology / Q000601:surgery*