title: Monitoring biological interactions using perforated evanescent-field-coupled waveguide-mode nanobiosensors.
abstract: Evanescent-field-coupled (EFC) waveguide-mode sensors recently been shown to be suitable for detecting various biomolecules. In the present studies, we demonstrated that both nucleic acids hybridization and nucleic acids-protein interactions can be analyzed using perforated evanescent-field-coupled waveguide-mode nanobio-sensors.
authors.affiliation: Center for Applied Near Field Optics Research (CAN-FOR), National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8562, Japan. gopi-subashchandrabose@aist.go.jp
authors.forename: Subash C B
authors.initials: SC
authors.lastname: Gopinath
authors.forename: Koichi
authors.initials: K
authors.lastname: Awazu
authors.forename: Makoto
authors.initials: M
authors.lastname: Fujimaki
authors.forename: Junji
authors.initials: J
authors.lastname: Tominaga
authors.forename: Kailash C
authors.initials: KC
authors.lastname: Gupta
authors.forename: Penmetcha K R
authors.initials: PK
authors.lastname: Kumar
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D001710:Biotin / Q000032:analysis; D008024:Ligands; D009693:Nucleic Acid Hybridization; D019809:Streptavidin / Q000032:analysis
chemical_list: D008024:Ligands; D001710:Biotin; D019809:Streptavidin