title: Effect of Hibiscus sabdariffa L. dried calyx ethanol extract on fat absorption-excretion, and body weight implication in rats.
abstract: The effect of Hibiscus sabdariffa L. (Hs) calyx extract on fat absorption-excretion and body weight in rats, was investigated. Rats were fed with either a basal diet (SDC = Control diet) or the same diet supplemented with Hs extracts at 5%, 10% and 15% (SD(5), SD(10) and SD(15)). Only SD(5) did not show significant increases in weight, food consumption and efficiency compared to SD(C). The opposite occurred in SD(15) group which showed a significant decrease for these three parameters. The SD(10) responses were similar to SD(15), with the exception of food consumption. In both SD(C) and SD(5) groups, no body weight loss was observed; however, only in the latter group was there a significantly greater amount of fatty acids found in feces. A collateral effect emerging from the study is that components of Hs extract at the intermediate and greater concentrations used in this experiment could be considered possible antiobesity agents.
authors.affiliation: Biochemical and Nutrition Chemistry Area, University of Veracruz, Boca del Río, CP 94294 Veracruz, Mexico. ocarvajal@uv.mx
authors.forename: O
authors.initials: O
authors.lastname: Carvajal-Zarrabal
authors.forename: P M
authors.initials: PM
authors.lastname: Hayward-Jones
authors.forename: Z
authors.initials: Z
authors.lastname: Orta-Flores
authors.forename: C
authors.initials: C
authors.lastname: Nolasco-Hipólito
authors.forename: D M
authors.initials: DM
authors.lastname: Barradas-Dermitz
authors.forename: M G
authors.initials: MG
authors.lastname: Aguilar-Uscanga
authors.forename: M F
authors.initials: MF
authors.lastname: Pedroza-Hernández
mesh_terms: D000042:Absorption; D000704:Analysis of Variance; D000818:Animals; D000431:Ethanol / Q000737:chemistry; D005227:Fatty Acids / Q000378:metabolism* / Q000652:urine; D005243:Feces / Q000737:chemistry; D035264:Flowers / Q000737:chemistry*; D031584:Hibiscus / Q000737:chemistry*; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D005227:Fatty Acids; D010936:Plant Extracts; D000431:Ethanol