title: Axiphenylalaninium and axityrosinium, modified amino acids from the Mediterranean marine sponge Axinella polypoides.
abstract: Two new modified amino acids, axiphenylalaninium (1) and axityrosinium (2), along with four known metabolites, C2-alpha-D-mannosylpyranosyl-L-tryptophan (3), N3,5'-cycloxanthosine (4), palythine (5), and taurine, were isolated from the marine sponge Axinella polypoides collected in the Mediterranean Sea. The structures were determined by spectroscopic studies and confirmed by X-ray analysis and chemical modifications.
authors.affiliation: Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Gabant
authors.forename: Marie-Thérèse
authors.initials: MT
authors.lastname: Martin
authors.forename: Céline
authors.initials: C
authors.lastname: Moriou
authors.forename: Ludmila
authors.initials: L
authors.lastname: Ermolenko
authors.forename: Vincent
authors.initials: V
authors.lastname: Guérineau
authors.forename: Pascal
authors.initials: P
authors.lastname: Retailleau
authors.forename: Odile
authors.initials: O
authors.lastname: Thoison
authors.forename: Nicole
authors.initials: N
authors.lastname: Boury-Esnault
authors.forename: Thierry
authors.initials: T
authors.lastname: Pérez
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Mourabit
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000302:isolation & purification*; D000818:Animals; D047089:Axinella / Q000737:chemistry*; D008386:Marine Biology; D008522:Mediterranean Sea; D015394:Molecular Structure
chemical_list: D000596:Amino Acids; C545047:axiphenylalaninium; C545048:axityrosinium