Fatal co-infection with swine origin influenza virus A/H1N1 and community-acquired methicillin-resistant Staphylococcus aureus.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) co-infection has been described previously in association with respiratory tract infection caused by seasonal influenza A viruses, but not with swine origin influenza A (H1N1) virus (S-OIV). We report the clinical and pathological findings of the first death with fulminant co-infection by CA-MRSA. Since early empirical treatment with beta-lactam plus fluoroquinolone or macrolides is often initiated before specimen collections, bacterial co-infection in S-OIV may have been under-reported.
Cheng
Vincent C C
VC
Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong, China.
Lau
Yuk-Kong
YK
Lee
Kwok-Lun
KL
Yiu
Kwan-Ho
KH
Chan
Kwok-Hung
KH
Ho
Pak-Leung
PL
Yuen
Kwok-Yung
KY
D000328:Adult; D000956:Antigens, Viral / Q000302:isolation & purification; D017714:Community-Acquired Infections / Q000150:complications* / Q000175:diagnosis; D017809:Fatal Outcome; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000175:diagnosis; D008168:Lung / Q000382:microbiology / Q000473:pathology / Q000821:virology; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D013203:Staphylococcal Infections / Q000150:complications* / Q000175:diagnosis
D000956:Antigens, Viral