title: Creutzfeldt-Jakob disease affecting the maxillofacial region: a case report.
abstract: Creutzfeldt-Jakob disease (CJD) is a rare disorder caused by prions that can affect any part of the central nervous system. It is characterised by an initial non-specific illness of varying duration, followed by progressive neurological decline. We report a patient with sporadic CJD who presented with neurological symptoms and bilateral dislocation of the temporomandibular joints (TMJs). To our knowledge this is the first report of sporadic CJD that involved the maxillofacial region.
authors.affiliation: Bradford Teaching Hospitals NHS Foundation Trust, St. Luke's Hospital, Bradford, United Kingdom. khalidabdelgalil@doctors.org.uk
authors.forename: Khalid
authors.initials: K
authors.lastname: Abdel-Galil
authors.forename: Christy
authors.initials: C
authors.lastname: Williams
authors.forename: Paul
authors.initials: P
authors.lastname: Chambers
mesh_terms: D048948:14-3-3 Proteins / Q000134:cerebrospinal fluid; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D004204:Joint Dislocations / Q000175:diagnosis*; D008875:Middle Aged; D009127:Muscle Rigidity / Q000175:diagnosis; D009207:Myoclonus / Q000175:diagnosis; D009418:S100 Proteins / Q000134:cerebrospinal fluid; D013705:Temporomandibular Joint Disorders / Q000175:diagnosis*
chemical_list: D048948:14-3-3 Proteins; D009418:S100 Proteins