title: Neonatal outcomes with the use of lamotrigine for bipolar disorder in pregnancy and breastfeeding: a case series and review of the literature.
abstract: The treatment of bipolar disorder in pregnant women and the postpartum period is a complex clinical issue requiring careful consideration of the risks involved in using psychotropic medications versus the benefits of successfully managing this chronic illness. We present three cases of women exposed to lamotrigine during pregnancy and breastfeeding, with follow up of their infants until 15-18 months of development.
authors.affiliation: Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Wakil
authors.forename: C Neill
authors.initials: CN
authors.lastname: Epperson
authors.forename: Juan
authors.initials: J
authors.lastname: Gonzalez
authors.forename: John P
authors.initials: JP
authors.lastname: O'Reardon
authors.forename: Deborah R
authors.initials: DR
authors.lastname: Kim
mesh_terms: D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D001942:Breast Feeding; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D000077213:Lamotrigine; D008297:Male; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D014227:Triazines / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D018692:Antimanic Agents; D014227:Triazines; D000077213:Lamotrigine