title: Cross-sectional validation of diabetes risk scores for predicting diabetes, metabolic syndrome, and chronic kidney disease in Taiwanese.
abstract: OBJECTIVE
  To validate the performance of current diabetes risk scores (DRSs) based on simple clinical information in detecting type 2 diabetes, metabolic syndrome (MetSyn), and chronic kidney disease (CKD).
  
  
  METHODS
  The performance of 10 DRSs was evaluated in a cross-sectional population screening of 2,759 Taiwanese subjects.
  
  
  RESULTS
  All DRSs significantly correlated with measures of insulin resistance, estimated glomerular filtration rate, and urine albumin excretion. The prevalence of screening-detected diabetes (SDM), MetSyn, and CKD increased with higher DRSs. For prediction of SDM, the Cambridge DRS by Griffin et al. and the Finnish DRS outperformed other DRSs in terms of discriminative power and model fit. For prediction of MetSyn and CKD, the Atherosclerosis Risk in Community Study score by Schmidt et al. outperformed other DRSs.
  
  
  CONCLUSIONS
  Risk scores based on simple clinical information are useful to identify individuals at high risk for diabetes, MetSyn, and CKD in different ethnic populations.
authors.affiliation: Metabolic Syndrome and Diabetes Screening Program, National Taiwan University Hospital Yun-Lin Branch, Dou-Liou City, Taiwan.
authors.forename: Jou-Wei
authors.initials: JW
authors.lastname: Lin
authors.forename: Yi-Cheng
authors.initials: YC
authors.lastname: Chang
authors.forename: Hung-Yuan
authors.initials: HY
authors.lastname: Li
authors.forename: Yu-Fen
authors.initials: YF
authors.lastname: Chien
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Wu
authors.forename: Ru-Yi
authors.initials: RY
authors.lastname: Tsai
authors.forename: Yenh-Chen
authors.initials: YC
authors.lastname: Hsieh
authors.forename: Yu-Jen
authors.initials: YJ
authors.lastname: Chen
authors.forename: Juey-Jen
authors.initials: JJ
authors.lastname: Hwang
authors.forename: Lee-Ming
authors.initials: LM
authors.lastname: Chuang
mesh_terms: D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005006:Ethnicity / Q000706:statistics & numerical data; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology*; D024821:Metabolic Syndrome / Q000453:epidemiology*; D011237:Predictive Value of Tests; D012372:ROC Curve; D044469:Racial Groups / Q000706:statistics & numerical data; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology