Ultrasound promoted one-pot synthesis of 3-aza-6,10-diaryl-2-oxa-spiro[4.5]decane-1,4,8-trione.
One-pot synthesis of 3-aza-6,10-diaryl-2-oxa-spiro[4.5]decane-1,4,8-trione from 1,5-diaryl-1,4-pentadien-3-one can be carried out in good yields at 50 degrees C under ultrasound irradiation. This method provided several advantages such as simple work-up procedure, shorter reaction time and higher yield.
Li
Ji-Tai
JT
College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, PR China. lijitai@hbu.cn
Zhai
Xin-Li
XL
Chen
Guo-Feng
GF
D000162:Acoustics; D000473:Alkanes / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D007659:Ketones / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D013053:Spectrophotometry / Q000379:methods; D013141:Spiro Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors; D014465:Ultrasonics; D014867:Water / Q000737:chemistry
C548089:3-aza-6,10-diaryl-2-oxa-spiro(4.5)decane-1,4,8-trione; D000473:Alkanes; D007659:Ketones; D013141:Spiro Compounds; D014867:Water; C012867:decane