Neonatal outcomes with the use of lamotrigine for bipolar disorder in pregnancy and breastfeeding: a case series and review of the literature.
The treatment of bipolar disorder in pregnant women and the postpartum period is a complex clinical issue requiring careful consideration of the risks involved in using psychotropic medications versus the benefits of successfully managing this chronic illness. We present three cases of women exposed to lamotrigine during pregnancy and breastfeeding, with follow up of their infants until 15-18 months of development.
Wakil
Laura
L
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Epperson
C Neill
CN
Gonzalez
Juan
J
O'Reardon
John P
JP
Kim
Deborah R
DR
D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D001942:Breast Feeding; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D000077213:Lamotrigine; D008297:Male; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D014227:Triazines / Q000009:adverse effects / Q000627:therapeutic use*
D018692:Antimanic Agents; D014227:Triazines; D000077213:Lamotrigine