title: The 'stem cell' concept: is it holding us back?
abstract: Developmental biology, regenerative medicine and cancer biology are increasingly occupied with the molecular characterization of stem cells. Yet recent work adds to a growing body of literature suggesting that 'stemness' cannot be reduced to the molecular features of cell types, and is instead an emergent property of cell lineages under feedback control.
authors.affiliation: Center for Complex Biological Systems, Department of Developmental and Cell Biology, and Department of Biomedical Engineering, University of California at Irvine, Irvine, CA 92697-2300, USA. adlander@uci.edu
authors.forename: Arthur D
authors.initials: AD
authors.lastname: Lander
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D049109:Cell Proliferation; D015509:Developmental Biology; D004777:Environment; D025461:Feedback, Physiological; D006801:Humans; D044968:Regenerative Medicine; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D009626:Terminology as Topic