title: [Long survival of a case of unresected duodenal cancer treated by S-1 before and after duodenojejunostomy].
abstract: A 52-year-old woman visited our hospital with epigastralgia. Detailed examination revealed a duodenal cancer of the ascending limbs. Since she refused the resection, the administration of S-1 alone was commenced. After one course of this treatment, oral intake became impossible. Duodenography and endoscopy showed duodenal obstruction, and she underwent surgery. The tumor proved to be unresectable due to direct invasion of the inferior vena cava. Duodenojejunostomy was performed. After surgery, she was treated by S-1 and survived 2 years and 11 months, which resulted in 3 years and 2 months' long survival from her first visit. The intervals of the intake and home stay, after the operation, were 2 years and 8 months and 2 years and 5 months, respectively. The combination of S-1 administration and bypass operation provides a useful alternative for the treatment of unresectable duodenal cancer with stenosis.
authors.affiliation: Dept. of Surgery, Saisei-kai Yokohama-shi Nanbu Hospital.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Matsuzu
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ike
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Cho
authors.forename: Akio
authors.initials: A
authors.lastname: Ashida
authors.forename: Hirohito
authors.initials: H
authors.lastname: Fujikawa
authors.forename: Beni
authors.initials: B
authors.lastname: Saito
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hayashi
authors.forename: Keita
authors.initials: K
authors.lastname: Fujii
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kojima
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Narui
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Fujii
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Makino
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Wada
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Rino
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004338:Drug Combinations; D004379:Duodenal Neoplasms / Q000628:therapy*; D004385:Duodenostomy; D005260:Female; D006801:Humans; D007582:Jejunostomy; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid