Correlations between polyphenolic composition and antioxidant activity of Venetian propolis.
Four propolis samples have been picked up in the Venetian region, from different orography and habitative density areas with the purpose to: (i) evaluate propolis' antioxidant activity, measured by inhibition of lipid peroxidation; (ii) determine the polyphenolic components--flavonoids and caffeic acid derivatives--which give antioxidant activity to propolis; (iii) verify the potential correlations between antioxidant activity, polyphenolic content, that has been determined by Folin-Ciocalteu, enzymatic, DPPH quenching, TEAC-like assays, and spectroscopic characteristics of propolis and (iv) correlate chemical structure and antioxidant efficacy of each of the major components. The possible localization of the lipophylic components of propolis into the phospholipidic bilayer by thermal analysis (DSC) and spin label EPR techniques has also been investigated.
Gregoris
Elena
E
Department of Physical Chemistry, University of Venice, Dorsoduro 2137, Venice 30123, Italy.
Stevanato
Roberto
R
D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D002109:Caffeic Acids / Q000737:chemistry / Q000494:pharmacology; D002152:Calorimetry, Differential Scanning; D002392:Catechin / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D004578:Electron Spin Resonance Spectroscopy; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology*; D007202:Indicators and Reagents; D007558:Italy; D015227:Lipid Peroxidation / Q000187:drug effects; D008081:Liposomes / Q000737:chemistry; D013058:Mass Spectrometry; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D059808:Polyphenols; D011429:Propolis / Q000737:chemistry*; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
D000975:Antioxidants; D001713:Biphenyl Compounds; D002109:Caffeic Acids; D005419:Flavonoids; D007202:Indicators and Reagents; D008081:Liposomes; D010636:Phenols; D010851:Picrates; D059808:Polyphenols; D002392:Catechin; D011429:Propolis; C004931:1,1-diphenyl-2-picrylhydrazyl