Primary hypergonadotrophic hypogonadism, alopecia totalis, and müllerian hypoplasia: a clinical study.
Two sisters with primary hypergonadotrophic hypogonadism associated with alopecia totalis, streak ovaries, absent or rudimentary uterus and markedly hypo plastic internal and external genitalia are presented. Their parents were first cousins.
Zaman
Shaikh Muhammad
SM
National Institute of Diabetes and Endocrinology, Ojha Campus, Dow University of Health Sciences, Karachi, Pakistan.
Nisar
Mehwish
M
D000328:Adult; D000506:Alopecia Areata / Q000175:diagnosis* / Q000235:genetics; D003241:Consanguinity; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis* / Q000235:genetics; D009095:Mullerian Ducts / Q000002:abnormalities / Q000473:pathology*; D010053:Ovary / Q000002:abnormalities; D010375:Pedigree; D014599:Uterus / Q000002:abnormalities