title: Primary intracranial leiomyomas: Report of two cases and review of the literature.
abstract: A leiomyoma is a benign neoplasm composed of smooth muscle cells that commonly occurs in the genitourinary and gastrointestinal tracts. Primary intracranial leiomyoma, however, is extremely rare and only a few cases have been reported to date. In this study, we present two cases of primary intracranial leiomyomas in middle-aged men. Magnetic resonance images (MRI) showed lesions with homogeneous low signals on T1-, T2-, diffusion-weighted, and FLAIR sequences. Tumors were totally removed and there was no evidence of recurrence in the follow-up study. Pathological analysis with immunohistochemistry revealed that tumors had characteristics of benign smooth muscles. A review of relevant literature has been conducted.
authors.affiliation: Department of Neurosurgery, Huashan Hospital, Fudan University, 12# Middle Wulumuqi Road, Shanghai 200040, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Hua
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
authors.forename: JiaWen
authors.initials: J
authors.lastname: Zhang
authors.forename: Yin
authors.initials: Y
authors.lastname: Wang
authors.forename: RenLing
authors.initials: R
authors.lastname: Mao
authors.forename: LiangFu
authors.initials: L
authors.lastname: Zhou
mesh_terms: D000328:Adult; D015415:Biomarkers; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D003399:Craniotomy; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000378:metabolism; D019635:Neurosurgical Procedures; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D009419:Nerve Tissue Proteins