title: Treatment of venous thromboembolism in patients with cancer: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET).
abstract: BACKGROUND
  The treatment of venous thromboembolism (VTE) in cancer patients remains controversial.
  
  
  OBJECTIVE
  The Italian Society for Thrombosis and Haemostasis (SISET) commissioned a project to develop clinical practice guidelines for the therapy of VTE in patients with malignancies.
  
  
  METHODS
  Key questions about the treatment of VTE in patients with malignancies were formulated by a multidisciplinary working group consisting of experts in clinical medicine and research. After a systematic review and discussion of the literature, recommendations were formulated and graded according to the supporting evidence. For those questions for which the literature search did not yield any definitive answer (absence of evidence evidence of low quality, and contradictory evidence), a formal consensus method was used to issue clinical recommendations.
  
  
  RESULTS
  The results of the available literature on VTE treatment in cancer patients were reviewed and clinical recommendations were drafted.
  
  
  CONCLUSIONS
  We describe the results of a systematic literature review and an explicit approach to consensus techniques which resulted in recommendations for the key therapeutic issues in cancer patients with VTE.
authors.affiliation: Emergency Department, Piacenza Hospital, Italy. d.imberti@ausl.pc.it
authors.forename: Davide
authors.initials: D
authors.lastname: Imberti
authors.forename: Marcello
authors.initials: M
authors.lastname: Di Nisio
authors.forename: Maria Benedetta
authors.initials: MB
authors.lastname: Donati
authors.forename: Anna
authors.initials: A
authors.lastname: Falanga
authors.forename: Angelo
authors.initials: A
authors.lastname: Ghirarduzzi
authors.forename: Daniele
authors.initials: D
authors.lastname: Guarneri
authors.forename: Franco
authors.initials: F
authors.lastname: Piovella
authors.forename: Rita Carlotta
authors.initials: RC
authors.lastname: Santoro
authors.forename: Edoardo
authors.initials: E
authors.lastname: Baldini
authors.forename: Stefania
authors.initials: S
authors.lastname: Zampogna
mesh_terms: D006801:Humans; D007558:Italy; D009369:Neoplasms / Q000097:blood / Q000150:complications*; D016896:Treatment Outcome; D054556:Venous Thromboembolism / Q000150:complications* / Q000628:therapy*