title: Nomenclature of ISCRl elements capable of mobilizing antibiotic resistance genes present in complex class 1 integrons.
abstract: The dissemination of many antibiotic resistance genes has arisen among members of the family Enterobacteriaceae. The dissemination mechanism of these antibiotic resistance genes is closely linked with insertion sequence common region 1 (ISCRl). Thus, caution must be taken in clinical settings to prevent further dissemination of these antibiotic resistance genes. A nomenclature system of ISCRl variants, important for the antibiotic resistance dissemination, was proposed. The proposed system can designate all ISCRl variants on the basis of the detection time and by considering amino-acid substitution(s) compared with ISCRla. This nomenclature system of ISCRl variants can be applied to 19 groups (ISCRl to ISCR19) of the ISCR family and help some researchers to correctly designate new ISCR subgroups.
authors.affiliation: Drug Resistance Proteomics Laboratory, Department of Biological Sciences, Myongji University, Gyeonggido 449-728, Republic of Korea.
authors.forename: Seung Ghyu
authors.initials: SG
authors.lastname: Sohn
authors.forename: Jae Jin
authors.initials: JJ
authors.lastname: Lee
authors.forename: Jae Seok
authors.initials: JS
authors.lastname: Song
authors.forename: Jung Hun
authors.initials: JH
authors.lastname: Lee
authors.forename: Ha Ik
authors.initials: HI
authors.lastname: Sun
authors.forename: Kwang Seung
authors.initials: KS
authors.lastname: Park
authors.forename: Ii Kwon
authors.initials: IK
authors.lastname: Bae
authors.forename: Jung-Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Byeong Chul
authors.initials: BC
authors.lastname: Jeong
authors.forename: Sang Hee
authors.initials: SH
authors.lastname: Lee
mesh_terms: D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects / Q000235:genetics*; D032023:Integrons; D008969:Molecular Sequence Data; D009626:Terminology as Topic