Recent extensions of the Morita-Baylis-Hillman reaction.
Significant progress in the development of the Morita-Baylis-Hillman (MBH) reaction has been made in the past decade. Many new variations of the MBH reaction have been well exploited, affording unexpected products and novel cyclized adducts in some cases, known as "abnormal MBH reactions". The formation of abnormal MBH adducts depends on the nature of the substrates and the employed catalytic system. This article will summarize recent advances in and mechanistic insights into such "abnormal" MBH reactions, including double-MBH reactions, sila-MBH reactions, abnormal aza-MBH reactions and tandem MBH pathways.
Ma
Guang-Ning
GN
Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.
Jiang
Jia-Jun
JJ
Shi
Min
M
Wei
Yin
Y