title: Anatomic resection of segment VIII of liver for hepatocellular carcinoma in cirrhotic patients based on an intrahepatic Glissonian approach.
abstract: BACKGROUND
  Isolated segmentectomy VIII is a technically demanding operative procedure and is reported only rarely. To our knowledge, no reports on anatomic segmentectomy based on an intrahepatic approach have been described. For cirrhotic patients with hepatocellular carcinoma (HCC) limited to segment VIII, this is a parenchyma-preserving hepatectomy that can be tolerated.
  
  
  METHODS
  Eighteen patients with HCC underwent anatomic segment VIII segmentectomy from January 2005 to January 2008 in our institution. The operative techniques, postoperative, and oncologic outcomes were reviewed.
  
  
  RESULTS
  Anatomic segmentectomy VIII was feasible with the technology described herein in all patients. The perioperative and oncologic outcomes were comparable with those of other similar hepatic resections. The median follow-up time was 28 months. The 3-year survival rate was 65%.
  
  
  CONCLUSIONS
  Although complex and technically demanding, an intrahepatic Glissonian approach for anatomic segmentectomy of segment VIII is an oncologically radical but parenchyma-sparing hepatic resection. In terms of preserving greater functioning liver parenchyma, it may be a safe and effective alternative to extensive hepatectomy.
authors.affiliation: Department of General Surgery, the Second Affiliated Hospital, XiangYa Medical College, Central South University, ChangSha, Hunan Province, China.
authors.forename: Ji-Xiong
authors.initials: JX
authors.lastname: Hu
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Dai
authors.forename: Xiong-Ying
authors.initials: XY
authors.lastname: Miao
authors.forename: De-Wu
authors.initials: DW
authors.lastname: Zhong
authors.forename: Sheng-Fu
authors.initials: SF
authors.lastname: Huang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wen
authors.forename: Shou-Zhi
authors.initials: SZ
authors.lastname: Xiong
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000601:surgery*; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008099:Liver / Q000601:surgery*; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome