[Liver transplantation in a patient with alcoholic cirrhosis: discussion about nonabstinence].
Liver transplantation is the recognized treatment for serious cases of alcoholic cirrhosis. However, due to their poor image within society, patients with alcoholic cirrhosis are often less referred to transplant centres. This is even more surprising since in terms of patient' and graft's survival, the results of transplantation are comparable, if not better, than in other indications. Transplantation is the treatment for the liver disease, not a treatment for alcoholism. In the case of severe alcoholic disease, a relapse is neither surprising nor unacceptable or insignificant if severe. In this case, it has an impact on the long-term survival, notably due to mortality by cancer. All the medical teams carrying out transplants agree that abstinence is necessary when a patient is being evaluated for liver transplantation. However, it is not proven that a set period of 6 months' abstinence prior to the transplantation can modify the results. The problem of alcoholism must be treated specifically in terms of addiction both before and after transplantation.
Pageaux
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Pôle digestif, service d'hépatogastroentérologie et transplantation hépatique, CHU Saint-Eloi, 80 rue Augustin-Fliche, Montpellier cedex 5, France. gp-pageaux@chu-montpellier.fr
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Chermak
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Bismuth
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Bouyabrine
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D000437:Alcoholism / Q000534:rehabilitation; D006085:Graft Survival; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D012307:Risk Factors; D055502:Secondary Prevention; D013695:Temperance; D013997:Time Factors; D016896:Treatment Outcome