title: Vision-related quality of life and emotional impact in children with strabismus: a prospective study.
abstract: The potential impact of the surgical correction of strabismus on vision-related quality of life (VRQOL) and the symptoms of anxiety and depression in children with strabismus remain unclear. The present study included 60 children with strabismus: 30 with heterophoria and 30 with heterotropia. A healthy age- and gender-matched control group (n = 60) was also recruited. The psychological instruments that were used were the short-form 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) and the Hospital Anxiety and Depression Scale (HADS). The results demonstrated that eight of the 12 NEI-VFQ-25 subscales were significantly impaired in children with strabismus compared with matched controls. Compared with pre-operative values, significant improvements were noted after surgery in the NEI-VFQ-25 summary score, and the anxiety and depression scores. This study demonstrated that the NEI-VFQ-25 instrument can be used in strabismus children and that surgical interventions can improve VRQOL, anxiety and depression in strabismus patients.
authors.affiliation: Department of Ophthalmology, Jiangxi Children's Hospital, Nanchang, Jiangxi Province, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Chai
authors.forename: Y
authors.initials: Y
authors.lastname: Shao
authors.forename: S
authors.initials: S
authors.lastname: Lin
authors.forename: K-Y
authors.initials: KY
authors.lastname: Xiong
authors.forename: W-S
authors.initials: WS
authors.lastname: Chen
authors.forename: Y-Y
authors.initials: YY
authors.lastname: Li
authors.forename: J-L
authors.initials: JL
authors.lastname: Yi
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: G
authors.initials: G
authors.lastname: Tan
authors.forename: J
authors.initials: J
authors.lastname: Tang
mesh_terms: D000342:Affective Symptoms / Q000523:psychology*; D001007:Anxiety / Q000523:psychology*; D002648:Child; D003863:Depression / Q000523:psychology*; D005260:Female; D006801:Humans; D009316:National Institutes of Health (U.S.); D011446:Prospective Studies; D011594:Psychometrics; D011788:Quality of Life; D012720:Severity of Illness Index; D013285:Strabismus / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014481:United States; D014786:Vision Disorders / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery; D014785:Vision, Ocular