title: One for all: the receptor-associated kinase BAK1.
abstract: The plant receptor kinase BAK1/SERK3 has been identified as a partner of ligand-binding leucine-rich repeat receptor kinases, in particular the brassinosteroid receptor BRI1 and the immune receptor FLS2. BAK1 positively regulates BRI1 receptor function via physical interaction and transphosphorylation. Since its first description in 2001, several independent groups have discovered BAK1/SERK3 as a component of diverse processes, including brassinosteroid signaling, light responses, cell death, and plant innate immunity. Here, we summarize current knowledge of the functional repertoire of BAK1 and discuss how its multiple functions could be integrated, how receptor complexes are potentially formed and how specificity might be determined.
authors.affiliation: Zürich-Basel Plant Science Center, Botanical Institute, University of Basel, 4056 Basel, Switzerland.
authors.forename: Delphine
authors.initials: D
authors.lastname: Chinchilla
authors.forename: Libo
authors.initials: L
authors.lastname: Shan
authors.forename: Ping
authors.initials: P
authors.lastname: He
authors.forename: Sacco
authors.initials: S
authors.lastname: de Vries
authors.forename: Birgit
authors.initials: B
authors.lastname: Kemmerling
mesh_terms: D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D008954:Models, Biological; D010766:Phosphorylation; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D011485:Protein Binding; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D010940:Plant Proteins; D011494:Protein Kinases; C463660:BAK1 protein, Arabidopsis; C108270:BRI1 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases