title: Non-accidental chlorpyrifos poisoning-an unusual cause of profound unconsciousness.
abstract: Chlorpyrifos is an organophosphorus anticholinesterase insecticide, and organophosphate intoxication can induce symptoms such as miosis, urination, diarrhea, diaphoresis, lacrimation, excitation of central nervous system, salivation, and consciousness disturbance (MUDDLES). Although accidental poisoning of children with drugs and chemicals is a common cause for consciousness disturbance in children, the possibility of deliberate poisoning is rarely considered. We report on a healthy 5-year 6-month-old boy with recurrent organophosphate intoxication. Reports of chlorpyrifos intoxication in children are quite rare. This case report demonstrates decision-making process and how to disclose deliberate chlorpyrifos poisoning of the toddler by the stepmother, another example of Munchausen syndrome by proxy.
authors.affiliation: Division of Pediatric Neurology, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, #5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
authors.forename: Jiun-Chang
authors.initials: JC
authors.lastname: Lee
authors.forename: Kuang-Lin
authors.initials: KL
authors.lastname: Lin
authors.forename: Jainn-Jim
authors.initials: JJ
authors.lastname: Lin
authors.forename: Shao-Hsuan
authors.initials: SH
authors.lastname: Hsia
authors.forename: Chang-Teng
authors.initials: CT
authors.lastname: Wu
mesh_terms: D002649:Child Abuse; D002675:Child, Preschool; D004390:Chlorpyrifos / Q000506:poisoning*; D003937:Diagnosis, Differential; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D016735:Munchausen Syndrome by Proxy / Q000175:diagnosis*; D014474:Unconsciousness / Q000175:diagnosis* / Q000209:etiology*
chemical_list: D007306:Insecticides; D004390:Chlorpyrifos