title: The Coalition Against Major Diseases: developing tools for an integrated drug development process for Alzheimer's and Parkinson's diseases.
abstract: Aiming to emulate the successful accelerated development of HIV/AIDS drugs, the Critical Path Institute (C-Path), in collaboration with the Engelberg Center for Health Care Reform at the Brookings Institution, has formed the Coalition Against Major Diseases (CAMD). Members include 6 nonprofit groups representing patients' interests, 15 leading pharmaceutical companies, the US Food and Drug Administration (FDA), the European Medicines Agency (EMEA), 2 institutes of the National Institutes of Health (NIH)-the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS)-and representatives from academia. The coalition's purpose is to transform the drug development paradigm for neurodegenerative diseases and serve as a model for other major diseases.
authors.affiliation: Coalition Against Major Diseases, Critical Path Institute, Tucson, Arizona, USA. kromero@c-path.org
authors.forename: K
authors.initials: K
authors.lastname: Romero
authors.forename: M
authors.initials: M
authors.lastname: de Mars
authors.forename: D
authors.initials: D
authors.lastname: Frank
authors.forename: M
authors.initials: M
authors.lastname: Anthony
authors.forename: J
authors.initials: J
authors.lastname: Neville
authors.forename: L
authors.initials: L
authors.lastname: Kirby
authors.forename: K
authors.initials: K
authors.lastname: Smith
authors.forename: R L
authors.initials: RL
authors.lastname: Woosley
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D015415:Biomarkers; D035843:Biomedical Research / Q000379:methods*; D018450:Disease Progression; D004345:Drug Industry; D006801:Humans; D007373:Interinstitutional Relations; D010300:Parkinson Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D055818:Public-Private Sector Partnerships
chemical_list: D015415:Biomarkers