Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates.
The addition of a Lewis acidic metal triflate salt Mg(OTf)(2) as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.
Linder
David
D
Département de Chimie Organique, Université de Genève, Quai Ernest Ansermet 30, 1211 Genève 4, Switzerland.
Austeri
Martina
M
Lacour
Jérôme
J