title: [Severe disseminated toxoplasmosis with atypical chorioretinitis. A case of primary infection].
abstract: The clinical diagnosis of ocular toxoplasmosis is based on clinical features and biological tests: polymerase chain reaction (PCR) and the determination of intraocular specific antibody secretion (Goldmann-Witmer coefficient) on aqueous humor. Older patients may have a higher prevalence of ocular involvement and more severe ocular disease during the acute phase of recently acquired systemic infection because of altered cell-mediated immunity. Moreover, the genotype of the infecting parasite (particularly involving neotropical Type I Toxoplasma gondii strain), appears to be an important determinant of disease severity.
authors.affiliation: Service d'Ophtalmologie, Hôpital Lariboisière, Assistance Publique Hôpitaux de Paris, Paris, France.
authors.forename: M H
authors.initials: MH
authors.lastname: Errera
authors.forename: S
authors.initials: S
authors.lastname: Chahed
authors.forename: H
authors.initials: H
authors.lastname: Man
authors.forename: Y J F
authors.initials: YJ
authors.lastname: Garin
authors.forename: J F
authors.initials: JF
authors.lastname: Bergmann
authors.forename: A
authors.initials: A
authors.lastname: Gaudric
authors.forename: P
authors.initials: P
authors.lastname: Massin
mesh_terms: D002825:Chorioretinitis / Q000000981:diagnostic imaging / Q000469:parasitology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012720:Severity of Illness Index; D014126:Toxoplasmosis, Ocular / Q000000981:diagnostic imaging