Subthalamic nucleus location: relationships between stereotactic AC-PC-based diagrams and MRI anatomy-based contours.
Subthalamic nucleus (STN) targeting is classically performed based on AC-PC probabilistic position. Nevertheless, MRI allows direct visualization and targeting. We aimed to compare the position localized on MR images with standard stereotactic diagrams. The STN was manually contoured on MR images (22 Parkinson's disease patients); boundaries were simplified in a schematic polygonal form. Front and lateral stereotactic diagrams were constructed according to Talairach and Benabid. We compared x, y and z coordinates of the geometrical center of MRI-based polygons and stereotactic diagrams (Wilcoxon matched-pairs tests). There was significant discordance between MRI-based polygons and AC-PC-based images. MRI shows the STN as more posterior, medial and slightly inferior.
Caire
François
F
Equipe de Recherche en Signal et Imagerie Médicale, EA 3295, Faculté de Médecine, Université Clermont 1, Clermont-Ferrand, France. francois.caire@chu-limoges.fr
Ouchchane
Lemlih
L
Coste
Jérôme
J
Gabrillargues
Jean
J
Derost
Philippe
P
Ulla
Miguel
M
Durif
Franck
F
Lemaire
Jean-Jacques
JJ
D000368:Aged; D046690:Deep Brain Stimulation; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D008953:Models, Anatomic; D008962:Models, Theoretical; D010300:Parkinson Disease / Q000473:pathology / Q000628:therapy; D013238:Stereotaxic Techniques; D020531:Subthalamic Nucleus / Q000473:pathology*; D020542:Third Ventricle / Q000473:pathology*