title: Effects of obesity on lower urinary tract symptoms in Korean BPH patients.
abstract: We analyzed the effects of obesity on lower urinary tract symptoms (LUTSs) in Korean benign prostatic hyperplasia (BPH) patients. This is a multicenter, cross-sectional, prospective study conducted in four centers in Korea. A total of 602 men with LUTSs secondary to BPH were included. BPH/LUTSs cases were men aged >/= 40 years with international prostate symptom scores (IPSS) > or = 8 points. Height, weight and waist circumference were measured. Among the 602 patients, 156 patients had a waist circumference above 90 cm, representing central obesity, and 215 patients had a body mass index above 25 kg m(-2). Waist circumference was positively correlated with prostate volume (P = 0.034). Men with waist circumference > 90 cm experienced a 1.36-fold increased risk of severe LUTSs (95% CI 0.82-2.41) compared with men with waist circumference < or = 90 cm. Prostate volume was positively correlated with urgency and nocturia in men with central obesity. In this population of Korean men diagnosed with BPH, central obesity rather than overall obesity seems to be the more important predictor of LUTSs correlated with BPH.
authors.affiliation: Department of Urology, Yonsei University Health System, Seoul 135-720, Korea.
authors.forename: Seung Hwan
authors.initials: SH
authors.lastname: Lee
authors.forename: Joon Chul
authors.initials: JC
authors.lastname: Kim
authors.forename: Ji-Youl
authors.initials: JY
authors.lastname: Lee
authors.forename: Jang Hwan
authors.initials: JH
authors.lastname: Kim
authors.forename: Cheol Young
authors.initials: CY
authors.lastname: Oh
authors.forename: Seung Wook
authors.initials: SW
authors.lastname: Lee
authors.forename: Se Jeong
authors.initials: SJ
authors.lastname: Yoo
authors.forename: Byung Ha
authors.initials: BH
authors.lastname: Chung
mesh_terms: D000328:Adult; D044466:Asian People; D003430:Cross-Sectional Studies; D006801:Humans; D007723:Korea; D008297:Male; D009765:Obesity / Q000150:complications*; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D055105:Waist Circumference