title: [Macular edema without fluorescein leakeage].
abstract: OBJECTIVE
  To study the OCT (optical coherence tomography) features of cases of unexplained macular edema, which were not combined with fluorescein leakage on angiography.
  
  
  METHODS
  We report a retrospective series of three patients who presented with visual acuity impairment due to unilateral macular thickening visible on OCT examination. All eyes studied underwent OCT and angiography and electrophysiological examinations. None of the patients had a medical record and none of the eyes studied was highly myopic.
  
  
  RESULTS
  OCT profiles shared characteristics of myopic foveoschisis or X-linked retinoschisis. No fluorescein leakage was detected on angiography. The electrooculogram was impaired in one eye while other electrophysiological investigations were normal in all eyes.
  
  
  CONCLUSIONS
  Most frequently, macular edemas are associated with a fluorescein leakage on angiography. Macular edemas without angiographic leakage may correspond to unilateral idiopathic retinoschisis or macular edemas, with an atypical mechanism of intraretinal fluid accumulation.
authors.affiliation: Service d'ophtalmologie, Université Louis Pasteur, Nouvel Hôpital Civil, Strasbourg, France. david.gaucher@chru-strasbourg.fr
authors.forename: D
authors.initials: D
authors.lastname: Gaucher
authors.forename: M
authors.initials: M
authors.lastname: Saleh
authors.forename: A
authors.initials: A
authors.lastname: Sauer
authors.forename: C
authors.initials: C
authors.lastname: Speeg-Schatz
authors.forename: T
authors.initials: T
authors.lastname: Bourcier
authors.forename: A
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence