Primary intracranial leiomyomas: Report of two cases and review of the literature.
A leiomyoma is a benign neoplasm composed of smooth muscle cells that commonly occurs in the genitourinary and gastrointestinal tracts. Primary intracranial leiomyoma, however, is extremely rare and only a few cases have been reported to date. In this study, we present two cases of primary intracranial leiomyomas in middle-aged men. Magnetic resonance images (MRI) showed lesions with homogeneous low signals on T1-, T2-, diffusion-weighted, and FLAIR sequences. Tumors were totally removed and there was no evidence of recurrence in the follow-up study. Pathological analysis with immunohistochemistry revealed that tumors had characteristics of benign smooth muscles. A review of relevant literature has been conducted.
Hua
Wei
W
Department of Neurosurgery, Huashan Hospital, Fudan University, 12# Middle Wulumuqi Road, Shanghai 200040, PR China.
Xu
Feng
F
Mao
Ying
Y
Zhang
JiaWen
J
Wang
Yin
Y
Mao
RenLing
R
Zhou
LiangFu
L
D000328:Adult; D015415:Biomarkers; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D003399:Craniotomy; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000378:metabolism; D019635:Neurosurgical Procedures; D014057:Tomography, X-Ray Computed
D015415:Biomarkers; D009419:Nerve Tissue Proteins