Plant 14-3-3 proteins catch up with their mammalian orthologs.
Members of the eukaryotic 14-3-3 family are highly conserved proteins that have been implicated in the modulation of distinct biological processes by phosphorylation-dependent protein-protein interactions. In plants, 14-3-3 mediated regulation of house-keeping proteins such as nitrate reductase and the plasma membrane localized H(+)-ATPase has been intensely studied. Recent proteome-wide approaches have indicated that the plant 14-3-3 interactome is comparable in size and functional complexity to its animal counterpart and, furthermore, shifted the focus of attention to signal mediators. In this regard, in vivo analyses of certain signaling proteins, such as BRASSINAZOLE-RESISTANT 1, a transcription factor controlling brassinosteroid responsive gene expression, verified an essential role for 14-3-3s in hormonal signal transduction processes.
Oecking
Claudia
C
Center for Plant Molecular Biology - Plant Physiology, University of Tübingen, Auf der Morgenstelle 5, 72076 Tübingen, Germany. claudia.oecking@zmbp.uni-tuebingen.de
Jaspert
Nina
N
D048948:14-3-3 Proteins / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D004268:DNA-Binding Proteins; D018506:Gene Expression Regulation, Plant; D009687:Nuclear Proteins / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000378:metabolism; D010944:Plants / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D020543:Proteome / Q000378:metabolism; D015398:Signal Transduction
D048948:14-3-3 Proteins; D029681:Arabidopsis Proteins; C454444:BZR1 protein, Arabidopsis; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D010937:Plant Growth Regulators; D020543:Proteome