Do men and women respond differently to percutaneous renal artery interventions?
BACKGROUND
Women have higher risk of contrast-induced nephropathy than men. The purpose of this study was to determine the relative impact of gender on long-term renal function after percutaneous renal interventions (PRI).


RESULTS
We included all patients undergoing PRI. Men (n = 72) and women (n = 28) had similar age, men had more diabetes, coronary and peripheral artery disease, higher serum creatinine and similar glomerular filtration rate (GFR), and prevalence of chronic kidney disease (CKD) stage > or =3 when compared with females. At follow-up, men had a significant improvement in GFR and systolic blood pressure, while females did not. The presence of severe CKD and male gender were the only predictors of long-term GFR improvement.


CONCLUSIONS
Male patients and patients with poor baseline renal function showed an important benefit with PRI, suggesting that it is not too late for renal revascularization if properly indicated.
Albertal
M
M
Research Department, Instituto Cardiovascular de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina. marianoalbertal@gmail.com
Nau
G
G
Padilla
L T
LT
Cura
F A
FA
Thierer
J
J
Belardi
J A
JA
D000368:Aged; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000098:blood supply; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012078:Renal Artery Obstruction / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D012737:Sex Factors; D015607:Stents
D003404:Creatinine