Impact of drug eluting stents on target vessel revascularization. A report from the Western Denmark heart registry from 2000 to 2004.
BACKGROUND
Limited information is available on target lesion revascularization (TLR) after percutaneous coronary intervention (PCI) in unselected patients at the beginning of the drug eluting stent (DES) era.


RESULTS
From January 2000 to September 2004 data from all PCI procedures in Western Denmark were recorded in the Western Danish Heart Registry. A total of 24,701 lesions were treated in 15,542 patients. Lesion length, stent length, frequency of complex lesions and age increased from 2000 to 2004. The use of DES increased from 0% in 2000, 2001, 2002 to 34% in 2003 and 54.0% in 2004 of all stents used. The clinical driven TLR declined from 9.4% in 2000 to 5.4% in 2004. The use of DES (OR 0.60; 95% CI 0.39-0.92, p=0.018) and procedure year (OR 0.89; 95% CI 0.83-0.97, p=0.008) and restenotic lesion (OR 1.51; 95% CI 1.18-1.93, p=0.001) were independent predictors of a TLR. Similar TLR rates were observed in diabetics (7.7%) and non-diabetic (7.0), p=NS.


CONCLUSIONS
In unselected PCI patients the TLR rate declined from 2000 to 2004. The use of DES was an independent predictor of TLR.
Jensen
Lisette Okkels
LO
Department of Cardiology Odense University Hospital, Odense, Denmark.
Maeng
Michael
M
Thayssen
Per
P
Lassen
Jens Flensted
JF
Bøtker
Hans Erik
HE
Rasmussen
Klaus
K
Thuesen
Leif
L