title: Inappropriate use of proton pump inhibitors.
abstract: BACKGROUND
  Proton pump inhibitors (PPIs) are widely used expensive medications.
  
  
  OBJECTIVE
  We performed a cross-sectional study to determine the extent and indication of PPI use in Irish acute medical wards.
  
  
  METHODS
  Fifty-five medical charts were reviewed at the beginning and end of 1 month.
  
  
  CONCLUSIONS
  Thirty-three patients were prescribed PPIs; 26 prior to admission. The prescribing of PPIs was concordant with guideline recommendations in only 30% of cases. Two-thirds of PPI use was unlicensed.
authors.affiliation: Department of Pharmacology and Therapeutics, St James's Hospital, Dublin 8, Ireland. debmolloy@eircom.net
authors.forename: D
authors.initials: D
authors.lastname: Molloy
authors.forename: A
authors.initials: A
authors.lastname: Molloy
authors.forename: C
authors.initials: C
authors.lastname: O'Loughlin
authors.forename: M
authors.initials: M
authors.lastname: Falconer
authors.forename: M
authors.initials: M
authors.lastname: Hennessy
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000627:therapeutic use; D000368:Aged; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004415:Dyspepsia / Q000188:drug therapy; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006801:Humans; D007494:Ireland; D064747:Lansoprazole; D008297:Male; D009853:Omeprazole / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data; D054328:Proton Pump Inhibitors / Q000008:administration & dosage* / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors; D013276:Stomach Ulcer / Q000188:drug therapy*
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D064747:Lansoprazole; D009853:Omeprazole