title: [Stress gastrointestinal bleeding in critically ill patients and its effect on the prognosis].
abstract: OBJECTIVE
  To investigate stress gastrointestinal bleeding in critically ill patients and its effect on the prognosis.
  
  
  METHODS
  Clinical data of 1148 critically ill patients consecutively admitted to Intensive Care Unit of East Campuses of Peking Union Medical College Hospital during 2008 were analyzed retrospectively. The main contents of investigation included morbility and mortality of stress gastrointestinal bleeding in critically ill patients and its relationship with multiple organ dysfunction.
  
  
  RESULTS
  Among the 1148 critically ill patients, organ dysfunction occurred in 254 cases, including 57 cases with shock, 124 with respiratory dysfunction, 46 with acute renal dysfunction, 192 with coagulation dysfunction and 40 with stress gastrointestinal bleeding. The patients with stress gastrointestinal bleeding took up 15.7% among organ dysfunction patients and 3.5% among critically ill patients. 97.5% stress gastrointestinal bleeding accompanied with other organ dysfunction. The mortality of stress gastrointestinal bleeding was 40.0%, which was higher than that of shock (28.1%), respiratory dysfunction (22.6%), renal dysfunction (30.4%) and coagulation dysfunction (13.5%) (all P<0.05). Binary Logistic regression analysis found that stress gastrointestinal bleeding was an independent risk factor associated with mortality (P<0.05).
  
  
  CONCLUSIONS
  The patients with stress gastrointestinal bleeding usually have a poor prognosis.
authors.affiliation: Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Wen-zhao
authors.initials: WZ
authors.lastname: Chai
authors.forename: Xiao-ting
authors.initials: XT
authors.lastname: Wang
authors.forename: Xiu-kai
authors.initials: XK
authors.lastname: Chen
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Da-wei
authors.initials: DW
authors.lastname: Liu
mesh_terms: D016638:Critical Illness; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D016015:Logistic Models; D011379:Prognosis; D012189:Retrospective Studies; D040701:Stress Disorders, Traumatic, Acute / Q000150:complications*