title: Validity and reliability of the Hamilton depression rating scale (5 items) for manic and mixed bipolar disorders.
abstract: Depressive symptoms during mania have prognostic value in bipolar disorder. For depressive symptoms, it has been proposed that shorter scales should be cost-effective and practical. To determine the usefulness of 5-item Hamilton Depression Rating Scale (HAMD-5) in manic and mixed bipolar disorder, we used a four-week follow-up prospective, observational study. Convergent and discriminant validity, internal consistency, and reliability were analyzed and compared with HAMD-21, HAMD-5, and HAMD-21 cut-off points were calculated versus CGI-BP. A total of 173 manic and mixed patients were evaluated. HAMD-5 showed appropriate convergent validity, discriminant validity, internal consistency, and test-retest reliability. Discriminant validity was higher for HAMD-5 than HAMD-21. Best cut-off point of remission was: HAMD-21 < or =5 and HAMD-5 < or =1. HAMD-5 presents appropriate validity and reliability estimates. It is comparable to HAMD-21 and focuses more specifically on depressive symptoms.
authors.affiliation: CIBERSAM Stanley Institute International Mood Disorders Research Center, Hospital Santiago Apóstol, University of the Basque Country, Vitoria, Alava, Spain. anamaria.gonzalez-pintoarrillaga@osakidetza.net
authors.forename: Ana
authors.initials: A
authors.lastname: González-Pinto
authors.forename: Fernando
authors.initials: F
authors.lastname: Mosquera
authors.forename: Catherine
authors.initials: C
authors.lastname: Reed
authors.forename: Diego
authors.initials: D
authors.lastname: Novick
authors.forename: Sara
authors.initials: S
authors.lastname: Barbeito
authors.forename: Patricia
authors.initials: P
authors.lastname: Vega
authors.forename: Jordan
authors.initials: J
authors.lastname: Bertsch
authors.forename: Susana
authors.initials: S
authors.lastname: Alberich
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Haro
mesh_terms: D000328:Adult; D017668:Age of Onset; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care / Q000592:standards; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales / Q000592:standards / Q000706:statistics & numerical data*; D011594:Psychometrics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires