Potent and selective inhibition of acid sphingomyelinase by bisphosphonates.
Roth
Anke G
AG
Institut für Chemie, Humboldt Universität zu Berlin, Brook-Taylor-Strasse 2, 12489 Berlin, Germany.
Drescher
Daniela
D
Yang
Yang
Y
Redmer
Susanne
S
Uhlig
Stefan
S
Arenz
Christoph
C
D000818:Animals; D017209:Apoptosis; D002478:Cells, Cultured; D004164:Diphosphonates / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000378:metabolism; D015394:Molecular Structure; D051381:Rats; D017208:Rats, Wistar; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004164:Diphosphonates; D007527:Isoenzymes; D013108:Sphingomyelin Phosphodiesterase