title: Intracellular biogenic silver nanoparticles for the generation of carbon supported antiviral and sustained bactericidal agents.
abstract: Intracellular silver nanoparticles produced by exposing silver ions to the fungus Aspergillus ochraceus were heat-treated in nitrogen environment to yield silver nanoparticles embedded in carbonaceous supports. This carbonaceous matrix embedded silver nanoparticles showed antimicrobial properties against both bacteria (Gram-positive and Gram-negative) and virus (M 13 phage virus). The bactericidal effects were noticed even after washing and repeated exposure of these carbon supported silver nanoparticles to fresh bacterial cultures, revealing their sustained activity.
authors.affiliation: Materials Chemistry Division, National Chemical Laboratory, Pune, 08, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Vijayakumar
authors.forename: B L V
authors.initials: BL
authors.lastname: Prasad
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001235:Aspergillus ochraceus / Q000166:cytology / Q000378:metabolism; D001412:Bacillus subtilis / Q000187:drug effects; D017104:Bacteriophage M13 / Q000187:drug effects; D002244:Carbon / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D042541:Intracellular Space / Q000378:metabolism*; D053768:Metal Nanoparticles / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000378:metabolism* / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D012834:Silver; D002244:Carbon