title: Refining the intrinsic chimera flap: a review.
abstract: Reconstruction of complex tissue deficiencies in which each missing component is in a different spatial relationship to each other can be particularly challenging, especially in patients with limited recipient vessels. The chimera flap design is uniquely suited to reconstruct these deformities. Chimera flaps have been previously defined in many ways with 2 main categories: prefabricated or intrinsic. Herein we attempt to clarify the definition of a true intrinsic chimeric flap and provide examples of how these constructs provide a method for reconstruction of complex defects. The versatility of the intrinsic chimera flap and its procurement from 7 different vascular systems is described. A clarification of the definition of a true intrinsic chimera flap is described. In addition, construction of flaps from the lateral femoral circumflex, deep circumflex iliac, inferior gluteal, peroneal, subscapular, thoracodorsal, and radial arterial systems is described to showcase the versatility of these chimera flaps. A true intrinsic chimera flap must consist of more than a single tissue type. Each of the tissue components receives its blood flow from separate vascular branches or perforators that are connected to a single vascular source. These vascular branches must be of appropriate length to allow for insetting with 3-dimensional spatial freedom. There are a multitude of sites from which true intrinsic chimera flaps may be harvested.
authors.affiliation: Division of Plastic and Reconstructive Surgery, University of Utah, Salt Lake City, UT, USA.
authors.forename: Jayant P
authors.initials: JP
authors.lastname: Agarwal
authors.forename: Shailesh
authors.initials: S
authors.lastname: Agarwal
authors.forename: Neta
authors.initials: N
authors.lastname: Adler
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Gottlieb
mesh_terms: D002678:Chimera / Q000145:classification* / Q000235:genetics; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006801:Humans; D007083:Iliac Artery / Q000601:surgery; D008297:Male; D008866:Microsurgery / Q000379:methods; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000637:transplantation; D017534:Radial Artery / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D012680:Sensitivity and Specificity; D013524:Surgical Flaps / Q000098:blood supply*