title: Antigenemia in patients with mediterranean visceral leishmaniasis.
abstract: Antigenemia in patients with Mediterranean visceral leishmaniasis (MVL) due to Leishmania infantum was retrospectively assessed by sandwich enzyme-linked immunosorbent assay (ELISA). Circulating Leishmania antigens, partially in free form, were in evidence in 53% of serum samples from immunocompetent individuals with MVL. Following successful therapy, antigenemia decline as measured by ELISA was more pronounced than antibody decrease.
authors.affiliation: Bâtiment Universitaire Archimed, INSERM U895, C3M, Equipe 6, 151 Route St Antoine de Ginestière, BP 2 3194, 06204 Nice Cedex 3, France. ferrua@unice.fr
authors.forename: Bernard
authors.initials: B
authors.lastname: Ferrua
authors.forename: Nicolas
authors.initials: N
authors.lastname: Rol
authors.forename: Grégory
authors.initials: G
authors.lastname: Michel
authors.forename: Pierre
authors.initials: P
authors.lastname: Marty
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000953:Antigens, Protozoan / Q000097:blood*; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D018314:Leishmania infantum / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000097:blood* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000953:Antigens, Protozoan; D000981:Antiprotozoal Agents