Axiphenylalaninium and axityrosinium, modified amino acids from the Mediterranean marine sponge Axinella polypoides.
Two new modified amino acids, axiphenylalaninium (1) and axityrosinium (2), along with four known metabolites, C2-alpha-D-mannosylpyranosyl-L-tryptophan (3), N3,5'-cycloxanthosine (4), palythine (5), and taurine, were isolated from the marine sponge Axinella polypoides collected in the Mediterranean Sea. The structures were determined by spectroscopic studies and confirmed by X-ray analysis and chemical modifications.
Gabant
Marion
M
Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Martin
Marie-Thérèse
MT
Moriou
Céline
C
Ermolenko
Ludmila
L
Guérineau
Vincent
V
Retailleau
Pascal
P
Thoison
Odile
O
Boury-Esnault
Nicole
N
Pérez
Thierry
T
Al-Mourabit
Ali
A
D000596:Amino Acids / Q000737:chemistry* / Q000302:isolation & purification*; D000818:Animals; D047089:Axinella / Q000737:chemistry*; D008386:Marine Biology; D008522:Mediterranean Sea; D015394:Molecular Structure
D000596:Amino Acids; C545047:axiphenylalaninium; C545048:axityrosinium