title: Transmission of an extended-spectrum-beta-lactamase-producing Escherichia coli (sequence type ST131) strain between a father and daughter resulting in septic shock and Emphysematous pyelonephritis.
abstract: Probable transmission of an extended-spectrum-beta-lactamase-producing Escherichia coli strain (sequence type ST131) between a father and daughter was documented. The father developed severe, recurrent pyelonephritis with multiple small abscesses; the daughter later developed septic shock, bacteremia, and extensive emphysematous pyelonephritis. This multidrug-resistant E. coli clone appears to be highly pathogenic and transmissible.
authors.affiliation: St. Luke's Hospital, 801 Ostrum Street, Bethlehem, PA 18015, USA. enderp@hotmail.com
authors.forename: Peter T
authors.initials: PT
authors.lastname: Ender
authors.forename: Deepakraj
authors.initials: D
authors.lastname: Gajanana
authors.forename: Brian
authors.initials: B
authors.lastname: Johnston
authors.forename: Connie
authors.initials: C
authors.lastname: Clabots
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Tamarkin
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
mesh_terms: D000038:Abscess / Q000382:microbiology; D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000382:microbiology; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D030561:Databases, Nucleic Acid; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000635:transmission*; D005192:Family Health; D005220:Fathers; D005260:Female; D005838:Genotype; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009679:Nuclear Family; D011704:Pyelonephritis / Q000150:complications* / Q000382:microbiology; D011860:Radiography, Abdominal; D012772:Shock, Septic / Q000150:complications* / Q000382:microbiology; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D004269:DNA, Bacterial; D001618:beta-Lactamases