Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophoramucronata.
Chemical examination of the endophytic fungus Pestalotiopsis sp., isolated from the leaves of the Chinese mangrove Rhizophora mucronata, yielded 11 new compounds including cytosporones J-N (1-3, 5-6), five new coumarins pestalasins A-E (8-12), and a new alkaloid named pestalotiopsoid A (14), along with the known compounds cytosporone C (4), dothiorelone B (7), and 3-hydroxymethyl-6,8-dimethoxycoumarin (13). The structures of the new compounds were unambiguously elucidated on the basis of extensive spectroscopic data analysis.
Xu
Jing
J
Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universität, Geb. 26.23, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.
Kjer
Julia
J
Sendker
Jandirk
J
Wray
Victor
V
Guan
Huashi
H
Edrada
RuAngelie
R
Müller
Werner E G
WE
Bayer
Mirko
M
Lin
Wenhan
W
Wu
Jun
J
Proksch
Peter
P
D000470:Alkaloids / Q000302:isolation & purification*; D000818:Animals; D001203:Ascomycota / Q000737:chemistry*; D002460:Cell Line; D003374:Coumarins / Q000302:isolation & purification*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D043982:Rhizophoraceae / Q000382:microbiology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D000470:Alkaloids; D003374:Coumarins