title: Specific absorbed fractions for internal electron emitters derived for a set of anatomically realistic reference pregnant female models.
abstract: The specific absorbed fraction (Phi), defined by the Medical Internal Radiation Dose Committee, is generally applied to evaluate the average absorbed dose in a target organ as a result of radioactive materials deposited in a source organ. This paper reports a new set of Phi values for internal electron emitters ranging from 10 keV to 4 MeV from various internal organs of the mother to the fetus based on three newly developed pregnant female tomographic models, called RPI-P3, RPI-P6 and RPI-P9. The results show a linear log relationship between Phi values and electron energy. The linear log coefficients have been derived and reported. The relationship between Phi values and mean distances between source organs and the fetus were also determined to allow for individual dosimetry. Since the RPI-P models have finer details of human anatomy and more realistic organ volumes and geometries, which follow the latest ICRP reference values, the newly derived Phi values could be used as reference values in determination of the dose to the fetus from internal electron emitters.
authors.affiliation: Radiation Oncology, University of Texas Health Science Center at San Antonio, Ste G240, San Antonio, TX 78229, USA.
authors.forename: Bingqi
authors.initials: B
authors.lastname: Guo
authors.forename: X George
authors.initials: XG
authors.lastname: Xu
authors.forename: Chengyu
authors.initials: C
authors.lastname: Shi
mesh_terms: D000328:Adult; D001822:Body Burden; D003198:Computer Simulation; D004583:Electrons; D005260:Female; D006801:Humans; D038622:Internationality; D008953:Models, Anatomic; D008954:Models, Biological; D011247:Pregnancy / Q000502:physiology*; D011829:Radiation Dosage; D012016:Reference Values; D012062:Relative Biological Effectiveness; D014915:Whole-Body Counting / Q000379:methods* / Q000592:standards*