title: Strategies for broad global access to pandemic influenza vaccines.
abstract: The global need for a pandemic influenza vaccine is large. High-income countries have stated their intent to provide universal access for pandemic influenza vaccine to their populations. Assuming that a two-dose schedule would be needed, providing universal coverage globally would represent approximately 6.5 billion two-dose courses or 13 billion doses. In the best case scenario, should an outbreak of pandemic influenza occur in the near term, using H5N1 as a proxy for the pandemic virus, the total available doses for the global population within six months of an out break would be only 1.2 billion courses or 2.4 billion doses. In addition, current stockpiles of pandemic influenza vaccine are limited. However, promising developments are occurring with respect to global capacity, technological innovation, and global conviction that offer potential solutions to the problem of pandemic influenza vaccine supply for the world's population.
authors.affiliation: Vanderbilt Vaccine Research Program, Vanderbilt University School of Medicine, 1161 21st Avenue South, CCC-5323 Medical Center North, Nashville, TN 37232, USA. kathryn.edwards@vanderbilt.edu
authors.forename: Kathryn M
authors.initials: KM
authors.lastname: Edwards
authors.forename: Adam
authors.initials: A
authors.lastname: Sabow
authors.forename: Andrew
authors.initials: A
authors.lastname: Pasternak
authors.forename: John W
authors.initials: JW
authors.lastname: Boslego
mesh_terms: D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D007252:Influenza Vaccines / Q000191:economics / Q000276:immunology* / Q000600:supply & distribution; D007251:Influenza, Human / Q000517:prevention & control*; D014611:Vaccination
chemical_list: D007252:Influenza Vaccines