title: The challenges of colorectal cancer survivorship.
abstract: With advances in treatment, colorectal cancer (CRC) is being transformed from a deadly disease into an illness that is increasingly curable. With this transformation has come increased interest in the unique problems, risks, needs, and concerns of survivors who have completed treatment and are cancer-free. Research has shown that physical and mental quality of life for CRC survivors was inferior compared with age-matched individuals without cancer. Although issues and symptoms were most prominent during the first 3 years, long-term effects of treatment can persist and include fatigue, sleep difficulty, fear of recurrence, anxiety, depression, negative body image, sensory neuropathy, gastrointestinal problems, urinary incontinence, and sexual dysfunction. The unique challenges and issues of CRC survivors can and should be addressed by health care providers and the research community to ensure effective interventions and models of care to manage these problems. This article discusses what is known about the long-term effects of CRC treatment on quality of life, the care of survivors, and existing models of survivorship care.
authors.affiliation: Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA. crystal.denlinger@fccc.edu
authors.forename: Crystal S
authors.initials: CS
authors.lastname: Denlinger
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Barsevick
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000150:complications* / Q000523:psychology*; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D006304:Health Status; D006801:Humans; D011788:Quality of Life / Q000523:psychology*; D011878:Radiotherapy / Q000009:adverse effects; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data
chemical_list: D000970:Antineoplastic Agents