Synthesis of the protein phosphatase 2A inhibitor (4S,5S,6S,10S,11S,12S)-cytostatin.
Bialy
Laurent
L
Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Waldmann
Herbert
H
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002625:Chemistry, Organic / Q000379:methods; D002626:Chemistry, Pharmaceutical / Q000379:methods; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry*; D006801:Humans; D020128:Inhibitory Concentration 50; D008956:Models, Chemical; D010755:Organophosphates / Q000138:chemical synthesis / Q000737:chemistry*; D010766:Phosphorylation; D054648:Protein Phosphatase 2 / Q000037:antagonists & inhibitors* / Q000737:chemistry; D011753:Pyrones / Q000138:chemical synthesis / Q000737:chemistry*; D013302:Streptomyces / Q000378:metabolism
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D010755:Organophosphates; D011753:Pyrones; C088526:cytostatin; D054648:Protein Phosphatase 2