Primary cutaneous nodular amyloidosis: case report and review of the literature.
Primary cutaneous nodular amyloidosis (PCNA) is a rare form of primary cutaneous amyloidosis. It presents as waxy yellow-red nodules that are located preferentially on the lower extremities, face, scalp, and genitals. Recognition of this condition is of particular importance, as primary systemic amyloidosis can have a similar cutaneous presentation. We report a case of PCNA in a 52-year-old woman with systemic lupus erythematosus (SLE) and Sjögren syndrome (SS). We discuss the need to evaluate for systemic disease and provide a concise review of the literature focusing on clinical presentation, disease associations, and management.
Schwendiman
Mark N
MN
Des Moines University College of Osteopathic Medicine and Surgery, Iowa, USA.
Beachkofsky
Thomas M
TM
Wisco
Oliver J
OJ
Owens
Nicole M
NM
Hodson
Darryl S
DS
D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*