Cord blood transplantation for haematological malignancies: conditioning regimens, double cord transplant and infectious complications.
Growing evidence supports the efficacy of cord blood transplantation (CBT) to treat patients with haematological malignancies, and the number of CBTs is rapidly increasing. Herein, we review considerations regarding conditioning regimens for CBT, the impact of double unit transplantation on CBT outcomes, and data regarding infectious complications following CBT.
Fred Hutchinson Cancer Research Center, University of Washington, D2-100, 1100 Fairview Ave North, Seattle, WA 98109, USA. sdelaney@fhcrc.org
Colleen
C
Delaney
Jonathan A
JA
Gutman
Frederick R
FR
Appelbaum
D000465:Algorithms; D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods*; D046148:Donor Selection / Q000379:methods; D019337:Hematologic Neoplasms / Q000628:therapy*; D006801:Humans; D009894:Opportunistic Infections / Q000209:etiology*; D019172:Transplantation Conditioning / Q000379:methods*; D014916:Whole-Body Irradiation / Q000379:methods