Arcopallium, NMDA antagonists and ingestive behaviors in pigeons.
This study investigated the effects of local injections of 6,7-dinitroquinoxaline-2,3(1H,4H)-dione (DNQX, AMPA-kainate receptor antagonist, 0.8 and 2.7 nmol) and MK-801 (NMDA receptor antagonist, 1.8 and 6.0 nmol) into the nucleus taeniae of the amygdala (TnA) and the arcopallium intermedium (AI) on ingestive and non-ingestive behaviors in free-feeding pigeons. Injections of DNQX into the TnA or into the AI failed to consistently affect feeding behavior; DNQX vehicle (DMSO) affected drinking when injected into the TnA. MK-801 injections into the AI produced a delayed increase in food and water intake. In the TnA, MK-801 increased water intake in the first two hours after the treatment. These data indicate that glutamatergic circuits in arcopallial structures in the pigeon, comparable to the mammalian medial amygdala, are involved in the inhibitory control of ingestive behaviors, suggesting that this can represent a conserved functional attribute in the amniote prosencephalon.
Department of Physiological Sciences, Centre of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900 Florianópolis, SC, Brazil.
Amanda Alcaraz
AA
da Silva
Luciane Coutinho de Azevedo
LC
Campanella
Mayara Caldas
MC
Ramos
Caroline
C
Parreira
Moacir Serralvo
MS
Faria
José
J
Marino-Neto
Marta Aparecida
MA
Paschoalini
D000679:Amygdala / Q000187:drug effects / Q000502:physiology; D000704:Analysis of Variance; D000818:Animals; D010856:Columbidae / Q000502:physiology*; D016291:Dizocilpine Maleate / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects; D004435:Eating / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects*; D008297:Male; D016548:Prosencephalon / Q000187:drug effects* / Q000502:physiology; D011810:Quinoxalines / Q000494:pharmacology*; D011930:Reaction Time / Q000187:drug effects; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors*
D011810:Quinoxalines; D016194:Receptors, N-Methyl-D-Aspartate; C056723:FG 9041; D016291:Dizocilpine Maleate