[Diabetes and vascular diabetic disease].
The prevalence of type 2 diabetes mellitus is growing. Vascular disease is here the main cause of morbidity and mortality, and accelerated atherosclerosis is responsible for about 80% of mortality and for about 75% of hospitalizations. In diabetics there is 2-4 times greater risk of ischemic heart disease in comparison to non-diabetics, and this risk is even greater in diabetic-females. Authors put greater attention to pathophysiology of diabetic vascular disease (inflammation and adipose tissue, metabolic and other--AGEs, ADMA--abnormalities, their contribution to endothelial dysfunction). The main concern is devoted to the treatment possibilities of diabetic vascular disease.
I. interná klinika Lekárskej fakulty UK Bratislava, Slovenská republika. murin@faneba.sk
J
J
Murín
M
M
Yaghy
D003924:Diabetes Mellitus, Type 2; D003925:Diabetic Angiopathies / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans