Biocatalytic promiscuity of lipase in chemoselective oxidation of aryl alcohols/acetates: a unique synergism of CAL-B and [hmim]Br for the metal-free H2O2 activation.
A unique synergistic combination of lipase and ionic liquid [hmim]Br is reported for metal-free H(2)O(2) activation, which is the first example of biocatalytic promiscuity of CAL-B for chemoselective oxidation of aryl alcohols/acetates. The catalytic system exhibits excellent functional group compatibility under neutral conditions besides reusability up to ten cycles thereby making the process economically and environmentally viable.
Natural Plant Products Division, Institute of Himalayan Bioresource Technology, CSIR, Palampur-176061 (H.P.), India.
Upendra K
UK
Sharma
Nandini
N
Sharma
Rakesh
R
Kumar
Rajesh
R
Kumar
Arun K
AK
Sinha
D000085:Acetates / Q000737:chemistry*; D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D005656:Fungal Proteins; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008049:Lipase / Q000378:metabolism*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000085:Acetates; D000438:Alcohols; D005656:Fungal Proteins; D006861:Hydrogen Peroxide; D008049:Lipase; C431349:lipase B, Candida antarctica