Physicochemical properties and antioxidant activities of luteolin-phospholipid complex.
A luteolin and phospholipid complex was prepared to improve the lipophilic properties of luteolin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD) and differential scanning calorimetry (DSC). The results showed that luteolin and phospholipid in the complex were joined by non-covalent-bonds and did not form a new compound. It was found that the complex was an effective scavenger of DPPH radicals, with an IC(50) value of 28.33 microg/mL. In the Rancimat antioxidant test using lard oil as substrate, the complex also showed the strong antioxidant activity.
College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, China. kyxky@163.com
Keyong
K
Xu
Benguo
B
Liu
Yuxiang
Y
Ma
Jiquan
J
Du
Guanglei
G
Li
Han
H
Gao
Yuan
Y
Zhang
Zhengxiang
Z
Ning
D000975:Antioxidants / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000378:metabolism; D002152:Calorimetry, Differential Scanning; D016166:Free Radical Scavengers / Q000494:pharmacology; D047311:Luteolin / Q000737:chemistry* / Q000494:pharmacology*; D010743:Phospholipids / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010743:Phospholipids; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D047311:Luteolin