Cortical enlightenment: are attentional gamma oscillations driven by ING or PING?
The response of a neuron to sensory stimuli can only give correlational support for functional hypotheses. To experimentally test causal function, the neural activity needs to be manipulated in a cell-type-specific as well as spatially and temporally precise way. We review recent optogenetic experiments on parvalbumin-positive cortical interneurons that link modeling studies of synchronization to experimental studies on attentional modulation of gamma oscillations in primates.
Donders Centre for Neuroscience, Radboud University Nijmegen, Nijmegen, The Netherlands.
Paul
P
Tiesinga
Terrence J
TJ
Sejnowski
D000818:Animals; D001288:Attention / Q000502:physiology*; D001683:Biological Clocks / Q000502:physiology*; D002540:Cerebral Cortex / Q000166:cytology*; D006801:Humans; D007395:Interneurons / Q000502:physiology*; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D013028:Space Perception / Q000502:physiology*