Cross-coupling of alkenyl/aryl carboxylates with Grignard reagent via Fe-catalyzed C-O bond activation.
Iron-catalyzed cross-coupling of alkenyl/aryl carboxylates with primary alkyl Grignard reagent was described. This reaction brought a new family of electrophiles to iron catalysis. The combination of an inexpensive carboxylate electrophile and an iron catalyst would generate ample advantages.
Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
Bi-Jie
BJ
Li
Li
L
Xu
Zhen-Hua
ZH
Wu
Bing-Tao
BT
Guan
Chang-Liang
CL
Sun
Bi-Qin
BQ
Wang
Zhang-Jie
ZJ
Shi
D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D007202:Indicators and Reagents / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
D000475:Alkenes; D002264:Carboxylic Acids; D007202:Indicators and Reagents; D002244:Carbon; D007501:Iron; D010100:Oxygen