In vitro genotoxicity of wastewaters from the town of Settat, Morocco.
In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution by household and industrial wastewaters, which are released into the Boumoussa River without any preliminary treatment. The river valley crosses the community of Mzamza 8 km to the north of the town. Years of drought forced members of the community to use this polluted ground water for irrigation and put themselves and the environment at risk.The aim of this study was to determine the physicochemical and metal profile of Settat wastewaters and to assess their impact on the water table. The second objective was to investigate the genotoxic potential of wastewater on human peripheral blood lymphocytes in vitro, using the micronucleus test and cellular proliferation index.This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes in vitro.
El Asslouj
Jaouad
J
Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco.
Amahdar
Loubna
L
Glouib
Kamal
K
Kholtei
Sanae
S
El Amrani Paaza
Namira
N
Verschaeve
Luc
L
Hilali
Abderraouf
A
D000328:Adult; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D007220:Industrial Waste / Q000032:analysis; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D019216:Metals, Heavy / Q000032:analysis; D015162:Micronucleus Tests; D009018:Morocco; D014865:Waste Disposal, Fluid; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*; D014881:Water Supply / Q000032:analysis*
D007220:Industrial Waste; D019216:Metals, Heavy; D014874:Water Pollutants, Chemical