Nursing some sense out of Myc.
Data recently published in BMC Biology provide insights into the normal physiological function of c-myc in the development and regeneration of the mammary gland and indicate a key role in epithelial cell proliferation, elaboration of ductal alveoli, and the biosynthetic capacity and milk production of the mature organ.
Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143-0502, USA.
Nicole M
NM
Sodir
Gerard I
GI
Evan
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D049109:Cell Proliferation; D004847:Epithelial Cells / Q000166:cytology; D005260:Female; D006801:Humans; D007774:Lactation; D042361:Mammary Glands, Human / Q000196:embryology / Q000502:physiology*; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics; D016271:Proto-Oncogene Proteins c-myc / Q000037:antagonists & inhibitors / Q000502:physiology*; D012038:Regeneration
D000970:Antineoplastic Agents; D016271:Proto-Oncogene Proteins c-myc