Zinc and copper concentrations in human preterm milk.
Zinc and copper are important trace elements in the nutrition of preterm infants. This study determined and compared the concentrations of zinc and copper in preterm milk of mothers receiving and not receiving zinc supplementation diets. The effects of maternal supplementation on the blood levels and anthropometric parameters were evaluated. Thirty-eight mothers and their preterm infants were enrolled in the study. Eighteen mothers were given a daily supplementation of 50 mg zinc, whereas the other 20 were not. Zinc and copper levels in milk were determined at 15-day intervals, as were blood zinc levels along with anthropometric parameters. Zinc and copper contents were determined by atomic absorption spectrophotometry. No significant differences were found between groups either for zinc values in maternal milk and infant blood or for anthropometric measurements. A pronounced decrease in copper levels was observed in mothers receiving supplemental zinc. Zinc supplementation given to mothers who were breastfeeding preterm infants had no significant effect on zinc secretion in milk.
Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil. carmensi@terra.com.br
Carmen Silvia Martimbianco
CS
de Figueiredo
Durval Batista
DB
Palhares
Petr
P
Melnikov
Aby Jaine da Cruz Montes
AJ
Moura
Sandra Christo
SC
dos Santos
D000293:Adolescent; D000328:Adult; D001942:Breast Feeding; D003300:Copper / Q000032:analysis* / Q000097:blood; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D008895:Milk, Human / Q000737:chemistry*; D015032:Zinc / Q000008:administration & dosage / Q000032:analysis* / Q000097:blood
D003300:Copper; D015032:Zinc