Severe cutaneous adverse reactions: emergency approach to non-burn epidermolytic syndromes.
BACKGROUND
Although severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome and toxic epidermal necrolysis, are rare, they are associated with considerable morbidity and mortality.


METHODS
The current knowledge regarding background, differential diagnoses, critical care and implications for inter-hospital emergency medical service (EMS) transport of these patients is discussed.


CONCLUSIONS
SCAR patients will substantially benefit from early interdisciplinary care and thorough consideration of complications during EMS transport and intensive care treatment.
Department of Plastic and Hand Surgery, Burn Trauma Center, Bergmannstrost Hospital, Merseburger Str 165, 06112 Halle/Saale, Germany. manuelstruck@web.de
Manuel Florian
MF
Struck
Peter
P
Hilbert
Maja
M
Mockenhaupt
Beate
B
Reichelt
Michael
M
Steen
D020099:Coated Materials, Biocompatible / Q000627:therapeutic use; D003422:Critical Care / Q000379:methods; D003937:Diagnosis, Differential; D004632:Emergency Medical Services; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D014945:Wound Healing
C042816:Biobrane; D020099:Coated Materials, Biocompatible; D007155:Immunologic Factors