Nonbonding interactions and stereoselection in the Corey-Bakshi-Shibata reduction.
Deuterium kinetic isotope effect measurements upon enantiotopic methyl groups for the Corey-Bakshi-Shibata reduction of 2',5'-dimethylphenyl isopropyl ketone suggest a complex role for nonbonding interactions in the mediation of stereoselection.
University of California, Merced, School of Natural Sciences, P.O. Box 2039, Merced, California 95344, USA. mmeyer@ucmerced.edu
Matthew P
MP
Meyer
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D001896:Boron Compounds / Q000737:chemistry; D003198:Computer Simulation; D004988:Ethers, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D007700:Kinetics; D008956:Models, Chemical; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000438:Alcohols; D001896:Boron Compounds; D004988:Ethers, Cyclic; D007659:Ketones