Functional profiling, identification, and inhibition of plasmepsins in intraerythrocytic malaria parasites.
Liu
Kai
K
Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore.
Shi
Haibin
H
Xiao
Huogen
H
Chong
Alvin G L
AG
Bi
Xuezhi
X
Chang
Young-Tae
YT
Tan
Kevin S W
KS
Yada
Rickey Y
RY
Yao
Shao Q
SQ
D000962:Antimalarials / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D001665:Binding Sites; D020134:Catalytic Domain; D003198:Computer Simulation; D010963:Plasmodium falciparum / Q000187:drug effects / Q000201:enzymology*
D000962:Antimalarials; D016282:Aspartic Acid Endopeptidases; C089643:plasmepsin