PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy.
Molteni
C G
CG
Te Kronnie
G
G
Bicciato
S
S
Villa
T
T
Tartaglia
M
M
Basso
G
G
Biondi
A
A
Cazzaniga
G
G
D002648:Child; D004171:Diploidy; D011905:Genes, ras; D006801:Humans; D009154:Mutation; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Q000235:genetics*
C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11