Intermediate-term outcome in lung transplantation from a donor with glioblastoma multiforme.
A 19-year-old man with cystic fibrosis, who was on extracorporeal membrane oxygenation, underwent bilateral lung transplantation from a donor with glioblastoma multiforme. Because the risk of tumor transmission from donor-related central nervous system malignancies remains unclear, the use of these extended donors remains controversial. In fact, there are few reports on the outcomes of lung transplantation from donors with central nervous system malignancy. This patient was critically ill with extracorporeal membrane oxygenation support before transplantation, but is well without any sign of malignancy 20 months after transplantation.
Toronto Lung Transplant Program, Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
Fengshi
F
Chen
Wojtek
W
Karolak
Marcelo
M
Cypel
Shaf
S
Keshavjee
Andrew
A
Pierre
D000328:Adult; D001932:Brain Neoplasms; D003550:Cystic Fibrosis / Q000601:surgery*; D005909:Glioblastoma; D006801:Humans; D008171:Lung Diseases / Q000601:surgery*; D016040:Lung Transplantation; D008297:Male; D012307:Risk Factors; D014019:Tissue Donors; D016896:Treatment Outcome