Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis.
An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.
Department of Radiology, University of Yamanashi, Chuo, Japan. utarohmotosugi@nifty.com
Utaroh
U
Motosugi
Tomoaki
T
Ichikawa
Hiroshi
H
Yamaguchi
Tadao
T
Nakazawa
Ryohei
R
Katoh
Jun
J
Itakura
Hideki
H
Fujii
Tadashi
T
Sato
Tsutomu
T
Araki
Michio
M
Shimizu
D001327:Autoimmune Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D050500:Pancreatitis, Chronic / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010950:Plasma Cells / Q000378:metabolism / Q000473:pathology; D012598:Sclerosis; D016896:Treatment Outcome
D007074:Immunoglobulin G