[Controllable bio-fabrication based on microbes].
Microorganisms in nature have rich variety, whose sizes are from nano scale to micro scale. Therefore, microbes can be used as natural "building blocks" in nano/micro multi-level fabrication processes. At present, most of the bio-manufacturing methods do not apply to direct control of living microbes. Their microbiological global functions and superiorities are not available. In this paper, two novel nano/micro bio-fabrication approaches, micro-fluidic control method and magnetic control method have been established. The living microbes could be manipulated to form micro-scaled patterns or to move orientedly. By these approaches, living microbes are taken as nano/micro robots. We could employ their specific biological functions and regulate their controllable self-assembly, which is expected to design and create a series of new special functional materials and devices.
National Engineering Research Center for Nano-Medicine, College of Life Science & Technology, Huazhong University of Science & Technology Wuhan 430074, China.
Xudian
X
Shi
Gang
G
Wang
Darning
D
Wang
Longjiang
L
Yu
Guang
G
Yang
D001419:Bacteria / Q000378:metabolism*; D032701:Biomimetics / Q000379:methods*; D001709:Biotechnology; D005658:Fungi / Q000378:metabolism*; D041822:Gluconacetobacter xylinus / Q000378:metabolism; D007218:Industrial Microbiology; D046210:Microfluidic Analytical Techniques / Q000379:methods; D008870:Microtubules; D036103:Nanotechnology; D012441:Saccharomyces cerevisiae / Q000378:metabolism