GSEL version 2, an online genome-wide query system of operon organization and regulatory sequence elements of Geobacter sulfurreducens.
Geobacter sulfurreducens is a model organism within the delta-Proteobacterial family Geobacteraceae, members of which can participate in environmental bioremediation of metal and organic waste contaminants and in production of bioenergy. In this report, we describe a new, significantly expanded and updated, version 2 of the GSEL (Geobacter Sequence Elements) database ( http://geobacter.org/research/gsel2/ and http://geobacter.org/refs/gsel2/ ) and its accompanying online query system, which compiles information on operon organization and regulatory sequence elements in the genome of G. sulfurreducens. It incorporates a new online graphical browser, provides novel search capabilities, and includes updated operon predictions along with new information on predicted and experimentally validated genome regulatory sites. The GSEL database and online search system provides a unique and comprehensive tool cataloging information about gene regulation in G. sulfurreducens, aiding in investigation of mechanisms that regulate its ability to generate electric power, bioremediate environmental waste, and adapt to environmental changes.
Qu
Yanhua
Y
Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Brown
Peter
P
Barbe
Jose F
JF
Puljic
Marko
M
Merino
Enrique
E
Adkins
Ronald M
RM
Lovley
Derek R
DR
Krushkal
Julia
J
D001483:Base Sequence; D030541:Databases, Genetic; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial; D045302:Geobacter / Q000235:genetics*; D006801:Humans; D020407:Internet; D009862:Online Systems; D009876:Operon; D012045:Regulatory Sequences, Nucleic Acid; D012984:Software; D014584:User-Computer Interface