Proton magnetic resonance spectroscopy and diffusion-weighted imaging of tumefactive demyelinating plaque.
Proton magnetic resonance spectroscopy, diffusion-weighted axonography, and diffusion tensor tractography in a patient with tumefactive demyelination plaque (TDP) were evaluated for differential diagnosis from glioblastoma. The findings of glutamate and glutamine elevations on magnetic resonance spectroscopy and apparent tracts within the lesion on axonography and tractography were unlikely to represent glioblastoma, and were thus useful for the preoperative diagnosis of TDP.
Department of Neurosurgery, Iwate Medical University, Morioka, Iwate.
Kazuki
K
Masu
Takaaki
T
Beppu
Shunrou
S
Fujiwara
Hideki
H
Kizawa
Hiroshi
H
Kashimura
Akira
A
Kurose
Kuniaki
K
Ogasawara
Makoto
M
Sasaki
D014408:Biomarkers, Tumor / Q000032:analysis; D001921:Brain / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000175:diagnosis*; D002634:Chemotaxis, Leukocyte; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D038524:Diffusion Magnetic Resonance Imaging; D056324:Diffusion Tensor Imaging; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D011237:Predictive Value of Tests; D011699:Putamen / Q000473:pathology; D011712:Pyramidal Tracts / Q000473:pathology; D012680:Sensitivity and Specificity
D014408:Biomarkers, Tumor