Nanosized silver-anionic clay matrix as nanostructured ensembles with antimicrobial activity.
Nanostructured ensembles of silver nanoparticles/zinc-substituted anionic clay matrix (Ag/ZnLDH) were obtained by a simple synthetic route in which reconstruction of the layered clay, synthesis of the silver nanoparticles and their organisation on the clay surface took place in a single step at room temperature. The morphology, composition and phase structure of the prepared powders were characterised by X-ray diffraction, infrared spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and N(2) adsorption. Results showed that the silver-anionic clay nanoarchitecture consists of nanoparticles of silver (average size 7 nm) deposited on the larger nanoparticles of clay (average size 85 nm). The antimicrobial activity was examined by disk diffusion assay and minimal inhibitory concentration determination as a function of x, where x is a controlled variable parameter that represents the length of time since the sample was synthesised. Ag/ZnLDH showed more stable antimicrobial properties than the unsupported nanosized silver.
Carja
Gabriela
G
Department of Chemical Engineering, Faculty of Chemical Engineering and Environment Protection, Technical University Gh Asachi of Iasi, Bd D Mangeron, Iasi, Romania. carja@uaic.ro
Kameshima
Yoshikazu
Y
Nakajima
Akira
A
Dranca
Cristian
C
Okada
Kiyoshi
K
D000538:Aluminum Silicates / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D000838:Anions / Q000737:chemistry / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000077215:Clay; D004926:Escherichia coli / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D012834:Silver / Q000737:chemistry / Q000494:pharmacology*; D013057:Spectrum Analysis; D013211:Staphylococcus aureus / Q000187:drug effects*
D000538:Aluminum Silicates; D000838:Anions; D000890:Anti-Infective Agents; D012834:Silver; D000077215:Clay