Staphylococcus aureus host cell invasion and post-invasion events.
Staphylococcus aureus is now recognized as a facultative intracellular pathogen. The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin.
Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Strasse 2, Bldg. E1, D-97080 Würzburg, Germany. bsinha@hygiene.uni-wuerzburg.de
Bhanu
B
Sinha
Martin
M
Fraunholz
D000818:Animals; D001427:Bacterial Toxins / Q000378:metabolism; D016923:Cell Death; D054884:Host-Pathogen Interactions; D006801:Humans; D010586:Phagocytes / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*; D010588:Phagosomes / Q000276:immunology / Q000378:metabolism / Q000382:microbiology; D013203:Staphylococcal Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000472:pathogenicity / Q000502:physiology*; D014774:Virulence
D001427:Bacterial Toxins