Topical chlormethine hydrochloride causing bullous reaction.
We describe a woman misusing chlormethine hydrochloride lotion for vitiligo with dermatological complications of local urticarial and bullous reactions. Presentations, complications, and management of topical chlormethine hydrochloride overdose are discussed. Surface decontamination and follow-up for potential complications are major treatments.
Ngai
Ka Yan
KY
Caritas Medical Centre, Hong Kong, SAR, China. a9820898@graduate.hku.hk
Chan
Ho Yin
HY
Ng
Fu
F
D000279:Administration, Cutaneous; D000328:Adult; D000477:Alkylating Agents / Q000008:administration & dosage / Q000506:poisoning*; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D001768:Blister / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D003666:Decontamination; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D004890:Erythema / Q000139:chemically induced; D005260:Female; D006801:Humans; D008466:Mechlorethamine / Q000008:administration & dosage / Q000506:poisoning*; D004366:Nonprescription Drugs / Q000506:poisoning; D012651:Self Medication; D013743:Tetanus Antitoxin / Q000627:therapeutic use; D016896:Treatment Outcome; D014820:Vitiligo / Q000188:drug therapy*
D000477:Alkylating Agents; D018926:Anti-Allergic Agents; D004366:Nonprescription Drugs; D013743:Tetanus Antitoxin; D008466:Mechlorethamine