[Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation].
Hepatitis A is generally known as a mild, self-limiting disease of the liver, but in rare instances it can progress to fulminant hepatitis, which may require liver transplantation for recovery. Such cases are known to be related to old age and underlying liver disease. We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (>/=39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis.
Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
Se Hoon
SH
Oh
Joon Hyoek
JH
Lee
Ji Won
JW
Hwang
Hye Young
HY
Kim
Chang Hoon
CH
Lee
Geum Youn
GY
Gwak
Moon Seok
MS
Choi
Kwang Chul
KC
Koh
Seung Woon
SW
Paik
Byung Chul
BC
Yoo
D058186:Acute Kidney Injury / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D000367:Age Factors; D005260:Female; D006505:Hepatitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis*; D006529:Hepatomegaly / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000209:etiology; D016031:Liver Transplantation; D008297:Male; D014057:Tomography, X-Ray Computed