Clinical effects of hypertension on the mortality of patients with acute myocardial infarction.
The incidence of ischemic heart disease has been increased rapidly in Korea. However, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class > or =III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade < or =2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
Kang
Dong Goo
DG
Kwangju Christian Hospital, Gwangju, Korea.
Jeong
Myung Ho
MH
Ahn
Yongkeun
Y
Chae
Shung Chull
SC
Hur
Seung Ho
SH
Hong
Taek Jong
TJ
Kim
Young Jo
YJ
Seong
In Whan
IW
Chae
Jei Keon
JK
Rhew
Jay Young
JY
Chae
In Ho
IH
Cho
Myeong Chan
MC
Bae
Jang Ho
JH
Rha
Seung Woon
SW
Kim
Chong Jin
CJ
Jang
Yang Soo
YS
Yoon
Junghan
J
Seung
Ki Bae
KB
Park
Seung Jung
SJ
D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D002561:Cerebrovascular Disorders / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D005260:Female; D006333:Heart Failure / Q000209:etiology; D017052:Hospital Mortality; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality* / Q000628:therapy; D016491:Peripheral Vascular Diseases / Q000209:etiology; D011237:Predictive Value of Tests; D012042:Registries; D012737:Sex Factors