Cashmirols A and B, new lipoxygenase inhibiting triterpenes from Sorbus cashmiriana.
Two new triterpenes, cashmirols A and B, along with three known compounds have been isolated from the AcOEt-soluble fraction of Sorbus cashmiriana, and their structures were elucidated by spectroscopic techniques including two-dimensional NMR. Both compounds displayed lipoxygenase enzyme inhibitory potential.
Department of Applied Chemistry, University of Karachi, Karachi-75270, Pakistan.
Mehdi Hassan
MH
Kazmi
Ejaz
E
Ahmed
Saira
S
Hameed
Abdul
A
Malik
Itrat
I
Fatima
Muhammad
M
Ashraf
D008084:Lipoxygenase / Q000737:chemistry* / Q000378:metabolism; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D031994:Sorbus / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D016859:Lipoxygenase Inhibitors; D014315:Triterpenes; C546100:cashmirol A; C546101:cashmirol B; D008084:Lipoxygenase