Atorvastatin: beyond lipid-lowering effects in the diabetic population.
Statins are the mainstay of therapy in coronary artery disease and hypercholesterolemia. Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor that is taken once daily. It has been shown to considerably reduce cardiovascular mortality events. Recently, several trials have demonstrated that atorvastatin has pleiotropic effects beyond its lipid-lowering capacities. Atorvastatin is especially beneficial in diabetics for stroke prevention and improving cardiovascular mortality risk.
Ramos
Julie
J
Emory University School of Medicine, Division of Cardiology, 69 Jesse Hill Drive SE, No. C247, Atlanta, GA 30303, USA.
Khan
Qamar A
QA
Thoenes
Martin
M
Khan
Bobby V
BV