Factors affecting calcium balance in Chinese adolescents.
Chinese dietary reference intakes (DRIs) for calcium were developed mainly from studies conducted amongst Caucasians, yet a recent review showed that reference calcium intakes for Asians are likely to be different from those of Caucasians (Lee and Jiang, 2008). In order to develop calcium DRIs for Chinese adolescents, it is necessary to explore the characteristics and potential influencing factors of calcium metabolic balance in Chinese adolescents. A total of 80 students (15.1+/-0.8 years) were recruited stratified by gender from a 1-year calcium supplementation study. Subjects were randomly designed to four groups and supplemented with calcium carbonate tablets providing elemental calcium at 63, 354, 660, and 966 mg/day, respectively. Subjects consumed food from a 3-day cycle menu prepared by staff for 10 days. Elemental calcium in samples of foods, feces, and urine was determined in duplicates by inductively coupled plasma atomic emission spectrometry. The total calcium intake ranged from 352 to 1323 mg/day. The calcium apparent absorption efficiency and retention in boys were significantly higher than that in girls (68.7% vs. 46.4%, 480 mg/day vs. 204 mg/day, P<0.05). Calcium retention increased with calcium intakes, but did not reach a plateau. Calcium absorption efficiency in boys increased with calcium intake up to 665 mg/day, and decreased after that. In girls, calcium absorption efficiency decreased with calcium intake. Calcium absorption efficiency increased within 1 year after first spermatorrhea in boys, but decreased with pubertal development in girls. Sex, calcium intake, age, and pubertal development were the most important determinants of calcium absorption (R(2)=0.508, P<0.01) and retention (R(2)=0.745, P<0.05). This study indicates that sex, calcium intake, age, and pubertal development are important factors for calcium retention and absorption during growth, which should be considered for the development of calcium DRIs for Chinese adolescents.
Yin
Jing
J
National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 7 Pan Jia Yuan Nan Li, Beijing 100021, China.
Zhang
Qian
Q
Liu
Ailing
A
Du
Weijing
W
Wang
Xiaoyan
X
Hu
Xiaoqi
X
Ma
Guansheng
G
D000293:Adolescent; D002118:Calcium / Q000378:metabolism*; D002119:Calcium Carbonate / Q000378:metabolism; D002136:Calcium, Dietary / Q000378:metabolism*; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology; D008297:Male
D002136:Calcium, Dietary; D002119:Calcium Carbonate; D002118:Calcium