Syntheses of glycoclusters containing a phosphocholine residue related to a glycosphingolipid from the earthworm Pheretima hilgendorfi.
Three types of glycoclusters related to an amphoteric glycosphingolipid found in the earthworm Pheretima hilgendorfi were synthesized. The glycoclusters were prepared from a common precursor and a simple approach for the rational design of a glycocluster was developed.
Hada
Noriyasu
N
Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan. hada-nr@pha.keio.ac.jp
Shida
Yukihiko
Y
Negishi
Natsuko
N
Schweizer
Frank
F
Takeda
Tadahiro
T
D000818:Animals; D005697:Galactosides / Q000138:chemical synthesis* / Q000737:chemistry; D006028:Glycosphingolipids / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009835:Oligochaeta / Q000737:chemistry*; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
D005697:Galactosides; D006028:Glycosphingolipids; C545762:N,N',N'-tri-(6-(6-O-phosphorylcoline-b-D-galactopyranosyl-(1'-6)-b - D-galactopyranosyloxy)hexyl)-1,3,5-benzenetriamide; D010767:Phosphorylcholine