Maternal levels of xenobiotics that affect fetal development and childhood health.
Children are not only being born into a chemically toxic world, they are exposed to these toxins throughout their gestational development. They are exposed to hundreds of toxic compounds via cord blood and release many of them in the meconium. These toxins include numerous neuro-, immuno-, and endocrine-toxic compounds present during the critical stages of hormonal, immunological, and neurological development. Outcome studies have shown that animal and human offspring who are so exposed can not only be born with birth defects, but suffer from lifelong health and behavior problems. This article discusses the effect of xenobiotics on fetal and child health, essential information for any health care provider working with women of childbearing age. Recommendations for maternal testing and dietary changes to avoid the greatest sources of exposure are also included.
Crinnion
Walter J
WJ
w.crinnion@scnm.edu
D002274:Carcinogens, Environmental / Q000633:toxicity*; D004785:Environmental Pollutants / Q000097:blood / Q000633:toxicity*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D047109:Fetal Development / Q000187:drug effects*; D006801:Humans; D007855:Lead Poisoning / Q000097:blood; D018811:Maternal Exposure; D008431:Maternal-Fetal Exchange; D008630:Mercury Poisoning / Q000097:blood; D011247:Pregnancy; D015262:Xenobiotics / Q000097:blood / Q000633:toxicity*
D002274:Carcinogens, Environmental; D004785:Environmental Pollutants; D015262:Xenobiotics