Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure.
Cristiano
C
Fava
Martina
M
Montagnana
Olle
O
Melander
D000818:Animals; D001794:Blood Pressure / Q000235:genetics; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism*; D000072470:Cytochrome P450 Family 4; D004195:Disease Models, Animal; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000378:metabolism*; D006973:Hypertension / Q000201:enzymology* / Q000235:genetics / Q000503:physiopathology; D051379:Mice; D008822:Mice, Transgenic; D013045:Species Specificity; D015854:Up-Regulation
D006893:Hydroxyeicosatetraenoic Acids; C055987:20-hydroxy-5,8,11,14-eicosatetraenoic acid; D003577:Cytochrome P-450 Enzyme System; D000072470:Cytochrome P450 Family 4; C117480:CYP4F2 protein, human