Tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP): efficient catalysts for the cyanosilylation and cyanocarbonation of aldehydes and ketones.
A variety of aldehydes and ketones were transformed to their corresponding cyanohydrin silyl ethers in good to excellent yields in the presence of 1-5 mol% of tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP). Cyanohydrin carbonates were also readily prepared using 5-10 mol% of TTMPP as an organocatalyst.
Department of Science Education, Faculty of Education, Ibaraki University, Ibaraki, 310-8512 Japan. smatsuka@mx.ibaraki.ac.jp
Satoru
S
Matsukawa
Izumi
I
Sekine
Ayumi
A
Iitsuka
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
D000447:Aldehydes; D007659:Ketones; D009570:Nitriles; D010720:Phosphines; D012821:Silanes; C544519:tris(2,4,6-trimethoxyphenyl)phosphine