Breast cancer during pregnancy.
Breast cancer in pregnancy is an uncommon situation but poses dilemmas for patients and their physicians. There is a paucity of prospective studies regarding diagnosis and treatment of breast cancer during pregnancy. Women diagnosed with breast cancer during pregnancy have similar disease characteristics to age-matched controls. Current evidence suggests that diagnosis may be carried out with limitations regarding staging. Surgical treatment may be performed as for non-pregnant women. Radiotherapy and endocrine or antibody treatment should be postponed until after delivery. Chemotherapy is allowed after the first trimester. Physicians should be aggressive in the workup of breast symptoms in the pregnant population to expedite diagnosis and allow multidisciplinary treatment without delay.
Vinatier
Edouard
E
Service de Chirurgie Gynécologique, Hôpital Jeanne de Flandre, 59037 Lille cedex, France.
Merlot
Benjamin
B
Poncelet
Edouard
E
Collinet
Pierre
P
Vinatier
Denis
D
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D004358:Drug Therapy; D005260:Female; D013502:General Surgery; D006801:Humans; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D011878:Radiotherapy; D012307:Risk Factors