[Effects of trivalent antimony on the rat hormonal status under experimental conditions].
The paper gives the data of experimental studies of oral trivalent antimony used at 1 and 20 maximum permissible concentrations (MPC) on the rat hormonal status. The findings are indicative of the specific features of changes in the hormonal status of experimental animals depending on the dose of trivalent antimony. The concentration of trivalent antimony at the level of 20 MPC is shown to act as a role of a reprotoxic agent that causes a change in the serum content of hormones, such as follicle-stimulating and luteinizing ones.
Kotliar
N N
NN
Koshkina
V S
VS
Setko
N P
NP
D000284:Administration, Oral; D000818:Animals; D000965:Antimony / Q000008:administration & dosage* / Q000633:toxicity; D004195:Disease Models, Animal; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008452:Maximum Allowable Concentration; D051381:Rats; D017208:Rats, Wistar; D012098:Reproduction / Q000187:drug effects*; D012735:Sexual Dysfunction, Physiological / Q000097:blood* / Q000139:chemically induced
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D000965:Antimony