The catalase-peroxidase KatG is required for virulence of Xanthomonas campestris pv. campestris in a host plant by providing protection against low levels of H2O2.
Xanthomonas campestris pv. campestris katG encodes a catalase-peroxidase that has a role in protecting the bacterium against micromolar concentrations of H(2)O(2). A knockout mutation in katG that causes loss of catalase-peroxidase activity correlates with increased susceptibility to H(2)O(2) and a superoxide generator and is avirulent in a plant model system. katG expression is induced by oxidants in an OxyR-dependent manner.
Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Thichakorn
T
Jittawuttipoka
Sarinya
S
Buranajitpakorn
Paiboon
P
Vattanaviboon
Skorn
S
Mongkolsuk
D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D015139:Blotting, Southern; D002374:Catalase / Q000235:genetics / Q000378:metabolism*; D006861:Hydrogen Peroxide / Q000633:toxicity*; D010544:Peroxidases / Q000235:genetics / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D031224:Raphanus / Q000382:microbiology; D014774:Virulence / Q000187:drug effects* / Q000235:genetics; D016959:Xanthomonas campestris / Q000187:drug effects / Q000201:enzymology / Q000472:pathogenicity
D001426:Bacterial Proteins; D006861:Hydrogen Peroxide; D010544:Peroxidases; D002374:Catalase