Invasive aspergillosis in paediatric oncology patients.
Invasive aspergillosis predominantly occurs in immunocompromised patients and is often resistant to different therapeutically strategies. However, mortality significantly increases if the central nervous system is affected. In this report we describe two cases of invasive aspergilosis, one with kidney involvement with a successful treatment while the other with pulmonary and cerebral involvement with a grave outcome.
Muda
Z
Z
Haematology-Oncology Unit, Hospital Kuala Lumpur, Malaysia. zuedr@yahoo.com
Ibrahim
H
H
Abdulrahman
E J
EJ
Menon
B S
BS
Zahari
Z
Z
Zaleha
A M
AM
Talib
A
A
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery*; D000077336:Caspofungin; D002648:Child; D002675:Child, Preschool; D054714:Echinocandins / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007668:Kidney / Q000382:microbiology / Q000601:surgery; D007674:Kidney Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D015470:Leukemia, Myeloid, Acute / Q000382:microbiology*; D055666:Lipopeptides; D008168:Lung / Q000382:microbiology / Q000601:surgery; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; C068538:liposomal amphotericin B; D000666:Amphotericin B; D000077336:Caspofungin