The effect of deep sclerectomy on intraocular pressure of normal-tension glaucoma patients: 1-year results.
OBJECTIVE
To study the intraocular pressure (IOP)-reducing effect of deep sclerectomy on normal-tension glaucoma (NTG) patients.


METHODS
We retrospectively analysed 21 eyes of 18 consecutive NTG patients who had undergone deep sclerectomy with mitomycin-C and a collagen implant.


RESULTS
Median (range) preoperative IOP was 15.1 mmHg (9.3-20.8) and median follow-up time 13 months (12-18). At the 1-year follow-up visit, median IOP was significantly (P < 0.001) reduced to 10.5 mmHg (4-15) with median IOP reduction from preoperative values of 37% (12-78). Laser goniopuncture was performed in 10 eyes (48%) 1-16 months postoperatively. After 13 months' follow-up, a complete success at 20%, 25% and 30% IOP reduction levels was achieved in 67%, 62% and 52% of eyes, respectively. Few complications were encountered, but these included reduced visual acuity, problems with conjunctiva, microperforation, hyphaema, Dellen formation and encapsulated bleb. We encountered no complications related to postoperative hypotony.


CONCLUSIONS
Deep sclerectomy with a collagen implant and mitomycin-C was a safe and effective method for reducing IOP in NTG patients during 1-year follow-up.
Suominen
Sakari
S
Department of Ophthalmology, Helsinki University Central Hospital, Finland. sakari.suominen@hus.fi
Harju
Mika
M
Ihanamäki
Tapio
T
Vesti
Eija
E
D020341:Absorbable Implants; D000368:Aged; D000867:Anterior Chamber / Q000601:surgery; D003094:Collagen / Q000008:administration & dosage; D003229:Conjunctival Diseases / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006988:Hyphema / Q000209:etiology; D007429:Intraocular Pressure; D007430:Intraoperative Care; D007431:Intraoperative Complications; D053685:Laser Therapy; D057066:Low Tension Glaucoma / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D011183:Postoperative Complications; D011184:Postoperative Period; D011677:Punctures; D012086:Reoperation; D012189:Retrospective Studies; D012599:Sclerostomy / Q000009:adverse effects / Q000379:methods*; D014792:Visual Acuity
D016685:Mitomycin; D003094:Collagen