Resolution of anti-neutrophil cytoplasmic antibody-associated vasculitis after resection of gastric cancer.
We report a case of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis in a 62-year-old patient with gastric cancer. The myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) level was threefold above normal preoperatively. Vasculitis was seen on renal biopsy. Gastric resection revealed well-differentiated adenocarcinoma and vasculitis. The MPO-ANCA level returned to normal post-operatively. Although ANCA-associated vasculitis occasionally accompanies malignant tumors, this is the first documented case of concurrent gastric cancer-associated and ANCA-associated vasculitis, with post-operative resolution of the vasculitis.
Department of Surgery, Jichi Medical University, 3311-1 Shimotsuke, Tochigi, 329-0498, Japan.
Yoshinori
Y
Hosoya
Seiji
S
Minota
Alan
A
Lefor
Kazuya
K
Sakuma
Yoko
Y
Aoki
Takeshi
T
Kamimura
Yasunori
Y
Niwa
Eiji
E
Kajii
Nobuyuki
N
Kanai
Yoshikazu
Y
Yasuda
D000230:Adenocarcinoma / Q000097:blood / Q000473:pathology* / Q000601:surgery; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000097:blood / Q000473:pathology*; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology; D012075:Remission, Spontaneous; D013274:Stomach Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery
D019268:Antibodies, Antineutrophil Cytoplasmic; D009195:Peroxidase