The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque.
Shiri
S
Kalet-Litman
Pedro R
PR
Moreno
Andrew P
AP
Levy
D000818:Animals; D001057:Apolipoproteins E / Q000235:genetics; D050197:Atherosclerosis / Q000378:metabolism* / Q000473:pathology; D005838:Genotype; D006242:Haptoglobins / Q000235:genetics*; D006454:Hemoglobins / Q000737:chemistry / Q000378:metabolism*; D007501:Iron / Q000032:analysis / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000737:chemistry; D051379:Mice; D008810:Mice, Inbred C57BL; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000235:genetics*; D011110:Polymorphism, Genetic
D001057:Apolipoproteins E; D006242:Haptoglobins; D006454:Hemoglobins; D007502:Iron Chelating Agents; D007501:Iron