Demonstration of x-ray microscopy with an x-ray laser operating near the carbon K edge.
High-brightness and short-pulse-width ( approximately 200 ps) x-ray lasers offer biologists the possibility of high-resolution three-dimensional imaging of specimens in an aqueous environment without the blurring effects associated with natural motions. As a first step toward developing the capabilities of this type of x-ray microscopy we have used a tantalum x-ray laser (lambda = 4.483 nm) together with an x-ray zone plate lens to image a test pattern. The observed image shows a detector-limited resolution of approximately 75 nm and paves the way to three dimensional biological imaging with high spatial resolution (20-30 nm).
Da Silva
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LB
Trebes
J E
JE
Mrowka
S
S
Barbee
T W
TW
Brase
J
J
Koch
J A
JA
London
R A
RA
Macgowan
B J
BJ
Matthews
D L
DL
Minyard
D
D
Stone
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G
Yorkey
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T
Anderson
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E
Attwood
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DT
Kern
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D