Emerging treatments for PTSD.
Recent innovations in posttraumatic stress disorder (PTSD) research have identified new treatments with significant potential, as well as novel enhancements to empirically-validated treatments. This paper reviews emerging psychotherapeutic and pharmacologic interventions for the treatment of PTSD. It examines the evidence for a range of interventions, from social and family-based treatments to technological-based treatments. It describes recent findings regarding novel pharmacologic approaches including propranolol, ketamine, prazosin, and methylenedioxymethamphetamine. Special emphasis is given to the description of virtual reality and D-cycloserine as enhancements to prolonged exposure therapy.
Weill Cornell Medical College, New York, NY 10065, USA. juc2010@med.cornell.edu
Judith
J
Cukor
Josh
J
Spitalnick
Joann
J
Difede
Albert
A
Rizzo
Barbara O
BO
Rothbaum
D015928:Cognitive Behavioral Therapy; D003130:Combat Disorders / Q000628:therapy*; D003198:Computer Simulation; D003523:Cycloserine / Q000627:therapeutic use; D006801:Humans; D007171:Implosive Therapy; D007398:Interpersonal Relations; D007649:Ketamine / Q000627:therapeutic use; D008016:Life Change Events; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000627:therapeutic use; D011224:Prazosin / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D013313:Stress Disorders, Post-Traumatic / Q000628:therapy*; D013315:Stress, Psychological / Q000628:therapy; D014584:User-Computer Interface
D007649:Ketamine; D003523:Cycloserine; D011433:Propranolol; D018817:N-Methyl-3,4-methylenedioxyamphetamine; D011224:Prazosin