Susceptibilities of 23 Desulfovibrio isolates from humans.
Antimicrobial susceptibilities of 23 strains of Desulfovibrio spp. were tested by Etest. Generally, Desulfovibrio spp. were highly susceptible to sulbactam-ampicillin, meropenem, clindamycin, metronidazole, and chloramphenicol: MIC(90)s of 6, 4, 0.19, 0.25, and 8 microg/ml, respectively. In addition, these strains generally showed high MICs to piperacillin and piperacillin-tazobactam. Desulfovibrio fairfieldensis (eight strains) was the species least susceptible to most agents, especially beta-lactams, and was the only species resistant to fluoroquinolones. Desulfovibrio desulfuricans strain Essex 6 isolates were less susceptible to beta-lactams than D. desulfuricans strain MB isolates.
Nakao
Ken-ichi
K
Department of Oral and Maxillofacial Sciences, Graduate School of Medicine, Gifu University, Gifu, Japan.
Tanaka
Kaori
K
Ichiishi
Suguru
S
Mikamo
Hiroshige
H
Shibata
Toshiyuki
T
Watanabe
Kunitomo
K
D000667:Ampicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002701:Chloramphenicol; D002981:Clindamycin / Q000494:pharmacology; D003901:Desulfovibrio / Q000145:classification* / Q000187:drug effects*; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D010878:Piperacillin / Q000494:pharmacology; D000077725:Piperacillin, Tazobactam Drug Combination; D013407:Sulbactam / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D008795:Metronidazole; D000077725:Piperacillin, Tazobactam Drug Combination; D002981:Clindamycin; D002701:Chloramphenicol; D000667:Ampicillin; D010397:Penicillanic Acid; D013407:Sulbactam; D010878:Piperacillin