Endovascular intervention for renal artery stenosis.
Renovascular diseases are common conditions with important implications on cardiovascular morbidity and mortality. Renal artery stenosis (RAS) is present in 1-5% of patients with hypertension (HTN) in the US with the vast majority of caused by atherosclerosis. Atherosclerotic RAS is related not only to uncontrolled HTN, but also to renal dysfunction. Atherosclerotic RAS in the USA has been reported to account for approximately 14-16% of new patients requiring dialysis each year. Hence a concerted effort was made in the last decade to treat renovascular stenosis using newly developed endovascular therapies to improve cardiovascular morbidity and renal function. A review on new advances in the endovascular management of renal artery stenosis with low profile stents, embolic protection devices, and drug eluting stents is presented.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Mallik
M
Thatipelli
Sanjay
S
Misra
D017130:Angioplasty / Q000379:methods; D050197:Atherosclerosis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D002986:Clinical Trials as Topic; D003952:Diagnostic Imaging; D054855:Drug-Eluting Stents; D057505:Embolic Protection Devices; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D006978:Hypertension, Renovascular / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D015995:Prevalence; D015641:Radiography, Interventional; D012078:Renal Artery Obstruction / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy*; D006435:Renal Dialysis; D014481:United States / Q000453:epidemiology