Neurofibroma adjacent to the thyroid gland and a thyroid papillary carcinoma in a patient with neurofibromatosis type 1: report of a case.
Neurofibromatosis (NF) type 1, also known as von Recklinghausen's disease, is an autosomal-dominant inherited disorder. Some tumors may develop in these patients, including optic pathway gliomas, astrocytomas, brainstem gliomas, chronic myeloid leukemia, and rhabdomyosarcoma. Patients with neurofibromatosis type 1 show also an increased risk of endocrine tumors, especially pheochromocytomas, whereas thyroid carcinoma is very rare. It is also rare for a neurofibroma to arise in the tissue neighboring the thyroid gland, and mimicking a nonfunctional thyroid nodule. This report presents a case of a neurofibroma adherent to the thyroid gland with thyroid papillary carcinoma in a 26-year-old woman with NF type 1.
Koksal
Yavuz
Y
Department of Pediatric Oncology, Selcuk University, Konya 42080, Turkey.
Sahin
Mustafa
M
Koksal
Hande
H
Esen
Hasan
H
Sen
Metin
M
D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009455:Neurofibroma / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000473:pathology*; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology*; D016896:Treatment Outcome