Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods.
Hirano
Kiriko
K
International Graduate School of Arts and Sciences, Yokohama City University, 22-2, Seto, Kanazawa-ku, Yokohama, 236-0027, Japan.
Macmillan
Derek
D
Tezuka
Katsunari
K
Tsuji
Takashi
T
Kajihara
Yasuhiro
Y
D055598:Chemical Phenomena; D015195:Drug Design; D004921:Erythropoietin / Q000031:analogs & derivatives* / Q000737:chemistry; D004926:Escherichia coli / Q000378:metabolism; D006801:Humans; D009844:Oligosaccharides / Q000737:chemistry*; D014176:Protein Biosynthesis
D009844:Oligosaccharides; C016735:sialooligosaccharides; D004921:Erythropoietin