Proton magnetic resonance spectroscopy and diffusion-weighted imaging of tumefactive demyelinating plaque.
Proton magnetic resonance spectroscopy, diffusion-weighted axonography, and diffusion tensor tractography in a patient with tumefactive demyelination plaque (TDP) were evaluated for differential diagnosis from glioblastoma. The findings of glutamate and glutamine elevations on magnetic resonance spectroscopy and apparent tracts within the lesion on axonography and tractography were unlikely to represent glioblastoma, and were thus useful for the preoperative diagnosis of TDP.
Masu
Kazuki
K
Department of Neurosurgery, Iwate Medical University, Morioka, Iwate.
Beppu
Takaaki
T
Fujiwara
Shunrou
S
Kizawa
Hideki
H
Kashimura
Hiroshi
H
Kurose
Akira
A
Ogasawara
Kuniaki
K
Sasaki
Makoto
M
D014408:Biomarkers, Tumor / Q000032:analysis; D001921:Brain / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000175:diagnosis*; D002634:Chemotaxis, Leukocyte; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D038524:Diffusion Magnetic Resonance Imaging; D056324:Diffusion Tensor Imaging; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D011237:Predictive Value of Tests; D011699:Putamen / Q000473:pathology; D011712:Pyramidal Tracts / Q000473:pathology; D012680:Sensitivity and Specificity
D014408:Biomarkers, Tumor