Similarity/dissimilarity studies of protein sequences based on a new 2D graphical representation.
A (two-dimensional) 2D graphical representation of protein sequences based on six physicochemical properties of amino acids is outlined. The numerical characterization of protein graphs is given as descriptors of protein sequences. It is not only useful for comparative study of proteins but also for encoding innate information about the structure of proteins. The coefficient of determination is proposed as a new similarity/dissimilarity measure. Finally, a simple example is taken to highlight the behavior of the new similarity/dissimilarity measure on protein sequences taken from the ND6 (NADH dehydrogenase subunit 6) proteins for eight different species. The results demonstrate the approach is convenient, fast, and efficient.
Yao
Yu-Hua
YH
College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, People's Republic of China. yaoyuhua2288@163.com
Dai
Qi
Q
Li
Ling
L
Nan
Xu-Ying
XY
He
Ping-An
PA
Zhang
Yao-Zhou
YZ
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry*; D000818:Animals; D003196:Computer Graphics; D006801:Humans; D008969:Molecular Sequence Data; D009245:NADH Dehydrogenase / Q000737:chemistry*; D021122:Protein Subunits / Q000737:chemistry; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein
D000596:Amino Acids; D021122:Protein Subunits; D009245:NADH Dehydrogenase