Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor.
As granulosa cell tumors of the adult type are extremely uncommon testicular neoplasms, relatively few case reports and case series have been published. Treatment for localized, small-volume, or oligometastatic disease is generally surgical resection alone. Visceral or widely metastatic disease is relatively rare, so there is no consensus approach to treatment. We report the case of an advanced granulosa cell tumor of the testis with a confirmed partial response to an angiogenesis inhibitor after initial resistance to cytotoxic chemotherapy.
Section of Hematology/Oncology, Department of Medicine, University of Wisconsin, UW Carbone Cancer Center, Madison, Wisconsin, USA. mrharris@medicine.wisc.edu
Michael R
MR
Harrison
Wei
W
Huang
Glenn
G
Liu
Jason
J
Gee
D000328:Adult; D000368:Aged; D006106:Granulosa Cell Tumor / Q000098:blood supply / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007191:Indazoles; D008297:Male; D009389:Neovascularization, Pathologic / Q000517:prevention & control*; D011743:Pyrimidines / Q000627:therapeutic use*; D016879:Salvage Therapy; D013449:Sulfonamides / Q000627:therapeutic use*; D013736:Testicular Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed
D007191:Indazoles; D011743:Pyrimidines; D013449:Sulfonamides; C516667:pazopanib