Analysis of clarithromycin resistance and CagA status in Helicobacter pylori by use of feces from children in Thailand.
The clarithromycin resistance and CagA status of Helicobacter pylori in Thai children were investigated using fecal samples. Of the 284 samples, H. pylori was detected in 120 samples, and the clarithromycin resistance rate was 29.2%. The cagA gene was detected in 59 samples, and only 6.8% of these samples contained the East Asian CagA type.
Tanuma
Michiya
M
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Rimbara
Emiko
E
Noguchi
Norihisa
N
Boonyaritichaikij
Surasak
S
Kuwabara
Kentaro
K
Fukunaga
Yoshitaka
Y
Sasatsu
Masanori
M
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000942:Antigens, Bacterial / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D017291:Clarithromycin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology*; D005260:Female; D016480:Helicobacter pylori / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D013785:Thailand / Q000453:epidemiology
D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C080866:cagA protein, Helicobacter pylori; D017291:Clarithromycin