Polarized diffuse reflectance measurements on cancerous and noncancerous tissues.
We report the measurement of polarization parameters (linear retardance, diattenuation and depolarization) of normal and malignant tissue from human oral cavity and breast over the spectral range 390 nm to 550 nm. These parameters were determined using the 3 x 3 Mueller matrix, the elements of which could be determined using linear polarization measurements only. The significant differences observed in the polarization parameters of the normal and malignant tissues appear to arise because of the changes in the collagen matrix in the two tissue types.
Laser Biomedical Applications and Instrumentation Division, R & D Block-D, Raja Ramanna Centre for Advanced Technology, Indore - 452013, India.
Sandeep
S
Manhas
Mahesh K
MK
Swami
Hari S
HS
Patel
Abha
A
Uppal
Nirmalya
N
Ghosh
Pradeep K
PK
Gupta
D000465:Algorithms; D001940:Breast / Q000166:cytology* / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003094:Collagen / Q000737:chemistry; D005109:Extracellular Matrix / Q000737:chemistry; D005260:Female; D006801:Humans; D008027:Light; D009055:Mouth / Q000166:cytology* / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000473:pathology*; D055620:Optical Phenomena; D010783:Photometry / Q000379:methods; D012542:Scattering, Radiation
D003094:Collagen