Cortical enlightenment: are attentional gamma oscillations driven by ING or PING?
The response of a neuron to sensory stimuli can only give correlational support for functional hypotheses. To experimentally test causal function, the neural activity needs to be manipulated in a cell-type-specific as well as spatially and temporally precise way. We review recent optogenetic experiments on parvalbumin-positive cortical interneurons that link modeling studies of synchronization to experimental studies on attentional modulation of gamma oscillations in primates.
Tiesinga
Paul
P
Donders Centre for Neuroscience, Radboud University Nijmegen, Nijmegen, The Netherlands.
Sejnowski
Terrence J
TJ
D000818:Animals; D001288:Attention / Q000502:physiology*; D001683:Biological Clocks / Q000502:physiology*; D002540:Cerebral Cortex / Q000166:cytology*; D006801:Humans; D007395:Interneurons / Q000502:physiology*; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D013028:Space Perception / Q000502:physiology*