[Spontaneous activity of cortical neurons in vitro and its regulation under the effect of acetylcholine].
In somatosensory cortical slices it was obtained that neuronal firing excitation evoked by iontophoretically applied acetylcholine was depended on the rate of spontaneous activity. The spontaneous firing rate was regulated simultaneously with dendritic properties and expression of cholinergic reaction. All of these findings may be a reflection of changing in K+ membrane permeability.
Mednikova
Iu S
IuS
Kopytova
F V
FV
Zhadin
M N
MN
D000109:Acetylcholine / Q000494:pharmacology* / Q000502:physiology; D000200:Action Potentials; D000818:Animals; D003712:Dendrites / Q000187:drug effects / Q000502:physiology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009044:Motor Cortex / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*
D000109:Acetylcholine