Multiple two-component systems of Streptococcus mutans regulate agmatine deiminase gene expression and stress tolerance.
Induction of the agmatine deiminase system (AgDS) of Streptococcus mutans requires agmatine and is optimal at low pH. We show here that the VicRK, ComDE, and CiaRH two-component systems influence AgDS gene expression in response to acidic and thermal stresses.
Department of Oral Biology, University of Florida, Gainesville, FL 32610, USA.
Yaling
Y
Liu
Robert A
RA
Burne
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D006867:Hydrolases / Q000235:genetics / Q000378:metabolism*; D009876:Operon / Q000235:genetics; D013295:Streptococcus mutans / Q000235:genetics / Q000378:metabolism*; D013312:Stress, Physiological; D013696:Temperature
D001426:Bacterial Proteins; C119939:YycF protein, Bacteria; D006867:Hydrolases; C019626:agmatine deiminase