Endoscopy-assisted surgery with topical mitomycin for a cholesterol granuloma in the petrous apex.
OBJECTIVE
We present the case of a 21-year-old woman who underwent endoscopy-assisted surgery with topical mitomycin for a large cholesterol granuloma in the petrous apex that involved the eustachian tube.


METHODS
Case report.


METHODS
Minimally invasive surgery was performed on the cholesterol granuloma with endoscopic assistance, and topical mitomycin (0.4 mg/mL) was administered to prevent scarring of the newly created drainage/ventilation route. With the endoscopic approach, the drainage/ventilation route was secured not only from the tympanic cavity, but also using a guidewire inserted from the pharyngeal orifice of the eustachian tube.


RESULTS
The drainage/ventilation route between the nasopharynx and middle ear cavity involving the cholesterol granuloma has been preserved more than for 9 months postoperatively. Her hearing has recovered.


CONCLUSIONS
This less invasive technique is a surgical option for patients with a large cholesterol granuloma in the petrous apex involving the eustachian tube.
Department of Otolaryngology, Osaka Medical College, Takatsuki, Japan.
Shin-Ichi
S
Haginomori
Atsuko
A
Mori
Atsuko
A
Kanazawa
Hiroshi
H
Takenaka
D000287:Administration, Topical; D002784:Cholesterol; D002921:Cicatrix / Q000517:prevention & control*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D015745:Granuloma, Foreign-Body / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007432:Intraoperative Period; D008279:Magnetic Resonance Imaging; D016685:Mitomycin / Q000008:administration & dosage*; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage; D010579:Petrous Bone; D014057:Tomography, X-Ray Computed; D055815:Young Adult
D019384:Nucleic Acid Synthesis Inhibitors; D016685:Mitomycin; D002784:Cholesterol