Case of pigmented neurofibroma with hypertrichosis with no association to neurofibromatosis.
Pigmented neurofibroma (PNF) is a rare cutaneous tumor that has been observed in patients with or without neurofibromatosis (NF). This tumor is histologically characterized by the coexistence of scattered melanin-laden cells and benign spindle cells with neural differentiations. Hypertrichosis is the excessive growth of hair on non-androgen-dependent areas of the body. It has been reported that hypertrichosis may sometimes overlie a neurofibroma. We highlight a case of PNF with hypertrichosis on a 17-year-old woman with no associated NF. We also discuss the possible underlying pathogenic mechanism of a localized hypertrichosis in PNF patients.
Department of Dermatology, Chosun University, Gwangju, Korea.
Chan Ho
CH
Na
In Guk
IG
Song
Byoung Soo
BS
Chung
Bong Seok
BS
Shin
D000293:Adolescent; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D006983:Hypertrichosis / Q000150:complications*; D009333:Neck / Q000473:pathology*; D009455:Neurofibroma / Q000150:complications / Q000473:pathology*; D012880:Skin Pigmentation