Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells.
Chen
Alex M
AM
Department of Chemistry Rutgers, The State of New Jersey, Newark, NJ 07102, USA.
Zhang
Min
M
Wei
Dongguang
D
Stueber
Dirk
D
Taratula
Oleh
O
Minko
Tamara
T
He
Huixin
H
D000970:Antineoplastic Agents / Q000008:administration & dosage; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D004317:Doxorubicin / Q000008:administration & dosage*; D019008:Drug Resistance, Neoplasm; D005260:Female; D019254:Genes, bcl-2; D006801:Humans; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D036103:Nanotechnology; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D034741:RNA, Small Interfering / Q000008:administration & dosage* / Q000235:genetics*; D012822:Silicon Dioxide
D000970:Antineoplastic Agents; D034741:RNA, Small Interfering; D012822:Silicon Dioxide; D004317:Doxorubicin