Use of Onyx (a patented ethylene-vinyl alcohol copolymer formulation) embolisation of cerebral arteriovenous malformations in Hong Kong: initial experience.
OBJECTIVE
To review the experience with Onyx embolisation of cerebral arteriovenous malformation.


METHODS
Prospective study.


METHODS
A regional neurosurgical centre in Hong Kong.


METHODS
Data of patients with cerebral arteriovenous malformation who underwent Onyx embolisation over a 14-month period were prospectively collected.


RESULTS
Eleven sessions of Onyx embolisation were performed in nine patients with cerebral arteriovenous malformations, seven of which had ruptured. Total occlusion was achieved in three (33%) of the patients, and subtotal occlusion (over 80% occlusion) in three out of four with Spetzler-Martin grade-III/IV malformations. One patient developed mild permanent neurological deficit.


CONCLUSIONS
Onyx embolisation of cerebral arteriovenous malformations is feasible in Hong Kong. Careful patient and target selection are important.
Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong. georgewong@surgery.cuhk.edu.hk
George K C
GK
Wong
Simon C H
SC
Yu
X L
XL
Zhu
Michael K M
MK
Kam
W S
WS
Poon
D000293:Adolescent; D000328:Adult; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006723:Hong Kong; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011145:Polyvinyls / Q000627:therapeutic use*; D011446:Prospective Studies; D016896:Treatment Outcome; D055815:Young Adult
C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide