EBV-associated hepatic smooth muscle tumor after lung transplantation: report of a case and review of the literature.
Post-transplant smooth muscle tumors (PTSMTs) are a rare and recently recognized neoplasm associated with Epstein-Barr virus (EBV). We describe the clinicopathologic, immunohistochemical and molecular features of a new case of EBV-associated PTSMT arising in the liver of a 55-year-old lung transplant recipient for lymphangioleiomyomatosis. To our knowledge, this is the third smooth muscle tumor (the second one proved to be associated with EBV) after lung transplantation. The 2 previous cases are reviewed and the differential diagnosis is also discussed.
Department of Pathology, Hospital Infanta Sofía, Po. de Europa n-34, San Sebastián de los Reyes, Madrid, Spain. javisalamanca_23@hotmail.com
Javier
J
Salamanca
Dolores Suárez
DS
Massa
D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D004854:Herpesvirus 4, Human; D006801:Humans; D008113:Liver Neoplasms / Q000821:virology*; D016040:Lung Transplantation / Q000009:adverse effects*; D018192:Lymphangioleiomyomatosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome