Ameloblastoma in children and adolescents.
This study first reviewed the data of 37 patients aged 18 years and younger with ameloblastoma over a 16-year period and then reviewed the literature on this subject from 1970 to 2009. Of 37 patients with ameloblastoma, 23 were male and 14 were female, a ratio of 1.6:1. The mean age was 14.8 years. All lesions were in the mandible. Clinical typing included 28 solid type and 9 unicystic type. Ten cases were recurrent (27.0%). A series of literature review disclosed 233 well-documented cases of ameloblastoma in children and adolescents. The ages ranged from 4 to 20 years with a mean age of 14.5 years. The distribution among males and females were almost identical: 53.6% (125/233) males and 46.4% (108/233) females (1.16:1). The mandible was affected in 225 (96.6%), the maxilla in 8 (3.4%). Histologically, solid type (63.1%) predominated over unicystic type (36.9%). Of 226, 123 (54.4%) patients were treated with radical resection, 103 (45.6%) underwent conservative method. Owing to a high recurrent rate of ameloblastoma, solid type of tumors should be approached with radical surgical treatment, while conservative measure can be applied selectively to unicystic type. Long-term follow-up is important because recurrence may appear years after tumor removal.
Department of Orthodontics, School of Stomatology, The Fourth Military Medical University, 145 West Changle Road, Xi'an, PR China. jingz77@163.com
Jing
J
Zhang
Zexu
Z
Gu
Lin
L
Jiang
Jinlong
J
Zhao
Meiyu
M
Tian
Jun
J
Zhou
Yinzhong
Y
Duan
D000293:Adolescent; D000564:Ameloblastoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D008441:Maxillary Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D055815:Young Adult