Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis.
An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.
Motosugi
Utaroh
U
Department of Radiology, University of Yamanashi, Chuo, Japan. utarohmotosugi@nifty.com
Ichikawa
Tomoaki
T
Yamaguchi
Hiroshi
H
Nakazawa
Tadao
T
Katoh
Ryohei
R
Itakura
Jun
J
Fujii
Hideki
H
Sato
Tadashi
T
Araki
Tsutomu
T
Shimizu
Michio
M
D001327:Autoimmune Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D050500:Pancreatitis, Chronic / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010950:Plasma Cells / Q000378:metabolism / Q000473:pathology; D012598:Sclerosis; D016896:Treatment Outcome
D007074:Immunoglobulin G