Three new phenolic glycosides and a new triterpenoid from the stems of Scolopia chinensis.
Three new phenolic glycosides, scolochinenosides C-E ( 1- 3), and a new triterpenoid, scolopianate A ( 4), were isolated from the stems of SCOLOPIA CHINENSIS, along with 15 known compounds. The structures of the new compounds were elucidated by means of extensive spectroscopic and chemical methods. Compound 3 contains a novel highly oxygenated lactone bridge ring attached at the aglycone. Six lanostane triterpenoids ( 10- 15) were discovered for the first time in a species other than GANODERMA LUCIDUM (Polyporaceae). In addition, the phenolic glycosides were evaluated for their inhibitory activity against snake venom phosphodiesterase I.
Lu
Ya-Nan
YN
Chai
Xing-Yun
XY
Xu
Zheng-Ren
ZR
Bi
Dan
D
Ren
Hong-Yan
HY
Zhao
Min
M
Tu
Peng-Fei
PF
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D043264:Phosphodiesterase I / Q000037:antagonists & inhibitors*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018547:Plant Stems; D031308:Salicaceae / Q000737:chemistry*; D012911:Snakes; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D004365:Drugs, Chinese Herbal; D004791:Enzyme Inhibitors; D005960:Glucosides; D006873:Hydroquinones; D010936:Plant Extracts; D014315:Triterpenes; C551644:scolochinenoside C; C551645:scolopianate A; D043264:Phosphodiesterase I; C470790:phosphodiesterase I, snake venom