Quantitative analysis of chemical constituents in different commercial parts of Notopterygium incisum by HPLC-DAD-MS.
BACKGROUND
Notopterygium incisum used as an antirheumatic and analgesic medicine for the treatment of rheumatism, headache, cold, etc., is not only a traditional Qiang medicine, but also a traditional Tibetan remedy for thousands of years.


OBJECTIVE
In order to use this herbal medicine in a more effective way, in the present investigation, we analyzed the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.


METHODS
All crude Notopterygium incisum samples used in this study were collected in Sichuan province of China. We used HPLC-DAD-MS to analyze quantitatively the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.


RESULTS
According to different commercial parts, 10 Notopterygium incisum samples collected from two main production areas have been investigated, and four main constituents have been quantitatively analyzed.


CONCLUSIONS
The quality of rhizomes is better than that of main roots. Unexpectedly, the content of two main constituents, notopterol and isoimperaorin, in fibrous roots is higher than any other parts of Notopterygium incisum. This result implied that the fibrous root may also have value, and we should study it to explore its potential.
Liu
Xin
X
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China.
Jiang
Shunyuan
S
Xu
Kaijie
K
Sun
Hui
H
Zhou
Yi
Y
Xu
Xuemin
X
Yi
Jinhai
J
Gu
Yucheng
Y
Ding
Lisheng S
LS
D019661:Apiaceae / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D015203:Reproducibility of Results; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*