Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor.
OBJECTIVE
Ectomesenchymal chondromyxoid tumor is a rare oral soft tissue neoplasm that should be differentiated from other neural and chondromyxoid entities. The aim of this study was to report the clinical, histological, and immunohistochemical features of 3 additional cases of this condition.


METHODS
Clinical data were obtained from the clinical records and all cases were evaluated through light microscopy and immunohistochemistry to cytokeratins, vimentin, S100 protein, desmin, smooth muscle actin, and glial fibrilary acidic protein.


RESULTS
All 3 cases affected the tongue as a long-lasting submucosal swelling and were managed through conservative surgery. They all showed myxoid and chondroid histological patterns, and vimentin, S100, and glial fibrilary acidic protein immunoexpression.


CONCLUSIONS
These findings reinforce the typical features of ectomesenchymal chondromyxoid tumor previously described, helping to confirm and establish the clinical, histopathological, and immunohistochemical profile of this uncommon lesion.
School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, Brazil. ramoafop@yahoo.com
Fábio Ramôa
FR
Pires
Aline Correa
AC
Abrahão
Márcia Grillo
MG
Cabral
Rebeca Souza
RS
Azevedo
Martinho Campolina Rebello
MC
Horta
Carlos Roberto
CR
Martins
Oslei Paes
OP
de Almeida
Sow-Yeh
SY
Chen
D000293:Adolescent; D000328:Adult; D000951:Antigens, Neoplasm / Q000276:immunology*; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008637:Mesenchymoma / Q000276:immunology / Q000473:pathology*; D008648:Mesoderm / Q000473:pathology; D009208:Myoepithelioma / Q000276:immunology / Q000473:pathology; D009232:Myxoma / Q000276:immunology / Q000473:pathology*; D009373:Neoplasms, Germ Cell and Embryonal / Q000276:immunology / Q000473:pathology*; D014062:Tongue Neoplasms / Q000276:immunology / Q000473:pathology*
D000951:Antigens, Neoplasm