Construction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations.
Nitrogen-centered radical cyclizations onto silyl enol ethers were utilized for the syntheses of protected polyhydroxylated pyrrolidines 2-hydroxymethyl-3-hydroxypyrrolidine and 1,4-dideoxy-1,4-imino-L-ribitol.
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, Canada V6T 1Z1.
Huimin
H
Zhai
Maria
M
Zlotorzynska
Glenn
G
Sammis
D000470:Alkaloids / Q000737:chemistry; D001089:Arabinose / Q000737:chemistry; D003500:Cyclization; D050113:Imino Furanoses / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry*; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000737:chemistry*; D013402:Sugar Alcohols / Q000737:chemistry
D000470:Alkaloids; D050113:Imino Furanoses; D011759:Pyrrolidines; D013402:Sugar Alcohols; C058137:1,4-dideoxy-1,4-iminoarabinitol; D001089:Arabinose; D009584:Nitrogen