SimCT: a generic tool to visualize ontology-based relationships for biological objects.
We present a web-based service, SimCT, which allows to graphically display the relationships between biological objects (e.g. genes or proteins) based on their annotations to a biomedical ontology. The result is presented as a tree of these objects, which can be viewed and explored through a specific java applet designed to highlight relevant features. Unlike the numerous tools that search for overrepresented terms, SimCT draws a simplified representation of biological terms present in the set of objects, and can be applied to any ontology for which annotation data is available. Being web-based, it does not require prior installation, and provides an intuitive, easy-to-use service.


BACKGROUND
http://tagc.univ-mrs.fr/SimCT.


BACKGROUND
Supplementary data are available at Bioinformatics online.
Herrmann
Carl
C
TAGC-U928 Inserm, Faculté des Sciences, Université de la Méditerranée, Campus de Luminy Case 928, Marseille, France. carl.herrmann@univmed.fr
Bérard
Sèverine
S
Tichit
Laurent
L
D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D003628:Database Management Systems; D016247:Information Storage and Retrieval; D012984:Software; D014584:User-Computer Interface