Multifocal diffuse oral melanoacanthoma: a case report.
Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains uncertain, its clinical behavior and spontaneous remission suggest a non-neoplastic nature. Clinically, it may present as a solitary or multifocal lesion; however these two variants exhibit different features. The clinical appearance of OMA is not pathognomonic and biopsy is mandatory. OMA requires no treatment or periodic observation. Here, we report a case of OMA with diffuse lesions also affecting the tongue in a 74-year-old black woman, whose diagnosis was based essentially on clinical and histological features. The immunohistochemical profile is also presented.
Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil. lumarocchio@usp.br
Luciana S
LS
Marocchio
Décio S P
DS
Júnior
Suzana C O M
SC
de Sousa
Rebeca F
RF
Fabre
Ricardo
R
Raitz
D049309:Acanthoma / Q000473:pathology*; D000368:Aged; D005260:Female; D006801:Humans; D008544:Melanocytes / Q000473:pathology; D008548:Melanosis / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*; D009365:Neoplasm Regression, Spontaneous