Nursing some sense out of Myc.
Data recently published in BMC Biology provide insights into the normal physiological function of c-myc in the development and regeneration of the mammary gland and indicate a key role in epithelial cell proliferation, elaboration of ductal alveoli, and the biosynthetic capacity and milk production of the mature organ.
Sodir
Nicole M
NM
Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143-0502, USA.
Evan
Gerard I
GI
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D049109:Cell Proliferation; D004847:Epithelial Cells / Q000166:cytology; D005260:Female; D006801:Humans; D007774:Lactation; D042361:Mammary Glands, Human / Q000196:embryology / Q000502:physiology*; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics; D016271:Proto-Oncogene Proteins c-myc / Q000037:antagonists & inhibitors / Q000502:physiology*; D012038:Regeneration
D000970:Antineoplastic Agents; D016271:Proto-Oncogene Proteins c-myc