[Application of thermoplastic elastomer in hot-melt pressure sensitive adhesives for transtermal drug delivery].
Development of drug dosage forms to a great extent depends on the development of drug auxiliary materials. The development of a new type of polymeric drug auxiliary materials will bring on the developing of a novel dosage forms technology and a flood of new drug dosage forms. Thermoplastic elastomer is a new type of drug polymeric auxiliary materials, at present, which has a broad application in the field of hot-melt pressure sensitive adhesives. This review mainly discussed a new transtermal Chinese drug delivery system, including matrix composition of the formula, modified thermoplastic elastomer for hot-melt pressure sensitive adhesives and their development prospects in the traditional Chinese drug delivery system. It suggested that thermoplastic elastomer of hot-melt pressure sensitive adhesives has broad development prospects in the field of the transtermal drug delivery system for traditional Chinese medicine.
Yan
Xiaoping
X
China Academy of Chinese Medicine Sciences Xiyuan Hospital, Beijing 100091, China.
Zheng
Rui
R
Guan
Shijie
S
Yi
Bowen
B
D000269:Adhesives / Q000737:chemistry; D000277:Adjuvants, Pharmaceutic / Q000737:chemistry*; D000279:Administration, Cutaneous; D016503:Drug Delivery Systems / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D020724:Elastomers / Q000737:chemistry; D006801:Humans; D012869:Skin Absorption
D000269:Adhesives; D000277:Adjuvants, Pharmaceutic; D004365:Drugs, Chinese Herbal; D020724:Elastomers