Arylation of benzo-fused 1,4-quinones by the addition of boronic acids under dicationic Pd(II)-catalysis.
The first examples of the direct arylation of benzo-fused 1,4-quinones by the dicationic Pd(II)-catalyzed addition of arylboronic acids are reported. The addition reaction is carried out under very mild conditions (dioxane-H(2)O, rt, open air atmosphere) and is tolerant of free OH groups. In addition, the reaction shows high regioselectivity when using nonsymmetrical quinones as starting materials.
Instituto de Química Médica (CSIC), C/Juan de la Cierva, 3, 28006-Madrid, Spain. mtmolina@iqm.csic.es
María Teresa
MT
Molina
Cristina
C
Navarro
Ana
A
Moreno
Aurelio G
AG
Csákÿ
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011809:Quinones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D001897:Boronic Acids; D011809:Quinones; D010165:Palladium