Biocatalytic promiscuity of lipase in chemoselective oxidation of aryl alcohols/acetates: a unique synergism of CAL-B and [hmim]Br for the metal-free H2O2 activation.
A unique synergistic combination of lipase and ionic liquid [hmim]Br is reported for metal-free H(2)O(2) activation, which is the first example of biocatalytic promiscuity of CAL-B for chemoselective oxidation of aryl alcohols/acetates. The catalytic system exhibits excellent functional group compatibility under neutral conditions besides reusability up to ten cycles thereby making the process economically and environmentally viable.
Sharma
Upendra K
UK
Natural Plant Products Division, Institute of Himalayan Bioresource Technology, CSIR, Palampur-176061 (H.P.), India.
Sharma
Nandini
N
Kumar
Rakesh
R
Kumar
Rajesh
R
Sinha
Arun K
AK
D000085:Acetates / Q000737:chemistry*; D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D005656:Fungal Proteins; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008049:Lipase / Q000378:metabolism*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000085:Acetates; D000438:Alcohols; D005656:Fungal Proteins; D006861:Hydrogen Peroxide; D008049:Lipase; C431349:lipase B, Candida antarctica