[Prognostic value of B-type natriuretic peptide in unstable angina and non-ST-elevation myocardial infarction].
OBJECTIVE
The B-type natriuretic peptide (BNP) has recently emerged as a prognostic marker in acute coronary syndromes (ACS). This role is based on results from randomized trials and other high selected population studies. The aim of this study was to determine the prognostic value of BNP in unselected patients with non-ST-elevated-ACS.


METHODS
BNP plasma concentrations were measured in 100 consecutive patients admitted in 2007 with non-ST-elevated-ACS, taking as cut-off value 80pg/ml (high BNP levels on 48% of patients).


RESULTS
After one year-of follow-up, 21 major adverse cardiovascular events occurred: 12 ACS, 7 hospitalizations for heart failure and 2 sudden cardiac deaths. No relationship was found between BNP levels and events on follow-up. BNP >80pg/ml was the only independent predictor of heart failure and death. No relationship was found between high levels of BNP and coronary events during the follow-up.


CONCLUSIONS
BNP was an independent predictor of heart failure and mortality in unselected patients with non-ST-elevated-ACS.
Molina-Mora
María José
MJ
Servicio de Cardiología, Hospital Universitario Virgen de la Victoria, Málaga, España. mj.molina.mora@gmail.com
Cabrera-Bueno
Fernando
F
Jiménez-Navarro
Manuel
M
Linde-Estrella
Antonio
A
García-Pinilla
José Manuel
JM
Teresa-Galván
Eduardo de
Ed
D000368:Aged; D000789:Angina, Unstable / Q000097:blood* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality / Q000503:physiopathology; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011379:Prognosis; D011446:Prospective Studies
D020097:Natriuretic Peptide, Brain