The evolution of ketamine applications in children.
Ketamine has found many applications in pediatric anesthetic practice. Insights into the mechanism of action and the pharmacokinetics and pharmacodynamics of its isomers have led to a re-evaluation of this drug, expanding the range of applications in children. Ketamine is a remarkably versatile drug that can be administered through almost any route. It can also be used for different purposes. The aim of this review is to look at the possible applications of this drug in children.
Division of Anesthesiology and Sedation, University of the Western Cape, Cape Town, South Africa. jaroelofse@uwc.ac.za
James A
JA
Roelofse
D000698:Analgesia; D000765:Anesthesia, Conduction; D000768:Anesthesia, General; D000778:Anesthetics, Dissociative / Q000493:pharmacokinetics / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007649:Ketamine / Q000493:pharmacokinetics / Q000494:pharmacology*
D000778:Anesthetics, Dissociative; D007649:Ketamine