[Viscoelastic properties of isolated papillary muscle: contributions of connective tissue skeleton and intracellular matrix].
Peculiarities of viscoelastic behavior of rabbit papillary muscle in passive state are studied by transversal versus longitudinal deformation curves, stress-strain and hysteresis curves, and stress relaxation curves under ramp stretching. The papillary muscle was chosen because of mostly longitudinal orientation of fibers and its elongated shape, which both make it as an appropriate model for uniaxial tests. The problem of evaluation of connective tissue protein structures and intracellular matrix contribution into the properties under consideration is solved by using the maceration method to remove intracellular structures. The different contribution of intracellular and extracellular protein features into total properties of a papillary muscle leads to nonlinearity of myocardial viscoelastic properties, such as the increase of differential elastic module and relaxation time with deformation.
Protsenko
Iu L
IuL
Kobelev
A V
AV
Lukin
O N
ON
Balakin
A A
AA
Smoliuk
L T
LT
D000818:Animals; D001696:Biomechanical Phenomena; D003238:Connective Tissue / Q000502:physiology* / Q000648:ultrastructure; D003599:Cytoskeleton / Q000502:physiology* / Q000648:ultrastructure; D055119:Elastic Modulus; D004548:Elasticity; D006321:Heart / Q000502:physiology*; D066298:In Vitro Techniques; D010210:Papillary Muscles / Q000502:physiology / Q000648:ultrastructure; D011817:Rabbits; D013314:Stress, Mechanical