Follow-up of collagen meniscus implant patients: clinical, radiological, and magnetic resonance imaging results at 5 years.
This study investigated at medium term follow-up the clinical outcomes and any progression of knee osteoarthritis in a population of patients that underwent arthroscopic placement of a collagen meniscus implant. Thirty-four patients underwent arthroscopic placement of a collagen meniscus implant for a symptomatic deficiency of medial meniscal tissue. Follow-up evaluation included Lysholm II score and Tegner activity scores and MR arthrography of the knee at 2 and 5 years after surgery. Plain radiographs were also obtained at 5 years. Six patients were excluded. In eight cases arthroscopic second look evaluation was performed. Lysholm and Tegner activity scores at 2 and 5 years after surgery improved significantly compared to the preoperative score. These patients showed good to excellent clinical results after 5 years from a CMI placement. The chondral surfaces of the medial compartment had not degenerated further since placement of the CMI. MR signal had continued to mature between 2 and 5 years after implant, progressively decreasing signal intensity but in any case comparable to the low signal of a normal meniscus. In most of cases the CMI-new tissue complex had a slight reduction in size, compared to a normal medial meniscus, but the new tissue had no apparent negative effects.
Department of Orthopedics and Trauma M. Boni, Insubria University, Viale Borri 57, Varese, Italy.
Paolo
P
Bulgheroni
Luigi
L
Murena
Chiara
C
Ratti
Erica
E
Bulgheroni
Mario
M
Ronga
Paolo
P
Cherubino
D000328:Adult; D001182:Arthroscopy; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000473:pathology*; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008592:Menisci, Tibial / Q000601:surgery* / Q000637:transplantation*; D008875:Middle Aged; D011859:Radiography; D020127:Recovery of Function; D000070600:Tibial Meniscus Injuries; D023822:Tissue Engineering; D014184:Transplantation, Homologous; D055815:Young Adult
D003094:Collagen