An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection.
An ultrasensitive DNAzyme-based colorimetric DNA detection strategy was developed by utilizing gold nanoparticles modified with both peroxidase-mimicking DNAzymes and capture DNAs and magnetic nanoparticles modified with another capture DNAs, with a detection limit for a model Chlamydia gene of 50 fM.
Fu
Rongzhan
R
Department of Chemical and Biomolecular Engineering, KAIST, Daejeon 305-701, Korea.
Li
Taihua
T
Park
Hyun Gyu
HG
D002689:Chlamydia / Q000235:genetics / Q000302:isolation & purification; D003124:Colorimetry / Q000379:methods*; D004247:DNA / Q000032:analysis*; D021881:DNA, Catalytic / Q000378:metabolism*; D006046:Gold / Q000737:chemistry; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry
D021881:DNA, Catalytic; D006046:Gold; D004247:DNA