Clinical and electrophysiological difference between idiopathic right ventricular outflow tract arrhythmias and pulmonary artery arrhythmias.
BACKGROUND
The precise incidence and characteristics of ventricular arrhythmias originating from the pulmonary artery have not been fully described. The purpose of this prospective study was to clarify these points.


METHODS
Thirty-three consecutive patients with an idiopathic left bundle branch block and inferior-axis deviation type ventricular arrhythmia were included. All patients underwent detailed electroanatomical mapping (CARTO, Biosense-Webster, Diamond Bar, CA, USA) during sinus rhythm prior to the catheter ablation. The precise location of the catheter tip at the successful ablation site was confirmed by both electroanatomical mapping and contrast radiography. The clinical and electrophysiological data were compared between the right ventricular outflow tract (RVOT) arrhythmia patients (RVOT group) and PA arrhythmia patients (PA group).


RESULTS
Eight patients (8/33 patients: 24.2%) had their ventricular arrhythmias successfully ablated within the PA. The local bipolar electrogram at the successful ablation sites in the PA group exhibited a significantly greater duration (P < 0.05) and lower amplitude (P < 0.05) than did those in the RVOT group (n = 19). In the PA group, all patients exhibited a multicomponent electrograms composed of a spiky potential and a dull potential, which might have consisted of near-field PA activation and a far-field ventricular activation, respectively, at the successful ablation site. Direct ablation to the spiky electrogram was able to eliminate the arrhythmias in all the PA group patients.


CONCLUSIONS
PA arrhythmias may be more common than previously recognized. Careful mapping and interpretation of low amplitude and multicomponent electrograms are important for recognizing ventricular arrhythmias originating from the PA.
Yamashina
Yoshihiro
Y
Division of Cardiology, Sendai City Hospital, Sendai, Japan.
Yagi
Tetsuo
T
Namekawa
Akio
A
Ishida
Akihiko
A
Sato
Hirokazu
H
Nakagawa
Takashi
T
Sakuramoto
Manjirou
M
Sato
Eiji
E
Yambe
Tomoyuki
T
D018780:Body Surface Potential Mapping / Q000379:methods*; D002037:Bundle-Branch Block / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000209:etiology*; D014694:Ventricular Outflow Obstruction / Q000150:complications* / Q000175:diagnosis*