Sex on the brain.
Release of testosterone during early development is necessary for masculinization of brain structures in rodents. Wu et al. (2009) now elucidate the neuronal changes caused by aromatase-mediated conversion of testosterone into estrogen in perinatal mice and the ensuing effects on adult behavior.
Gagnidze
Khatuna
K
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Pfaff
Donald W
DW
D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000502:physiology*; D004967:Estrogens / Q000096:biosynthesis*; D012727:Sex Characteristics
D004967:Estrogens