Phylogeny and disease association of Shiga toxin-producing Escherichia coli O91.
The diversity and relatedness of 100 Shiga toxin-producing Escherichia coli O91 isolates from different patients were examined by multilocus sequence typing. We identified 10 specific sequence types (ST) and 4 distinct clonal groups. ST442 was significantly associated with hemolytic uremic syndrome.
Mellmann
Alexander
A
Institute of Hygiene and the National Consulting Laboratory on Hemolytic Uremic Syndrome, Münster, Germany. mellmann@uni-muenster.de
Fruth
Angelika
A
Friedrich
Alexander W
AW
Wieler
Lothar H
LH
Harmsen
Dag
D
Werber
Dirk
D
Middendorf
Barbara
B
Bielaszewska
Martina
M
Karch
Helge
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D015373:Bacterial Typing Techniques; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000032:analysis; D003967:Diarrhea / Q000503:physiopathology / Q000821:virology; D004926:Escherichia coli / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000503:physiopathology / Q000821:virology; D029968:Escherichia coli Proteins / Q000235:genetics*; D006463:Hemolytic-Uremic Syndrome / Q000503:physiopathology / Q000821:virology; D006801:Humans; D007223:Infant; D008875:Middle Aged; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D012720:Severity of Illness Index; D054323:Shiga-Toxigenic Escherichia coli / Q000235:genetics*; D014774:Virulence; D055815:Young Adult
D004269:DNA, Bacterial; D029968:Escherichia coli Proteins