Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge.
BACKGROUND
As intraductal papilloma (IP) includes both benign and malignant lesions, it is difficult to decide whether the patient should merely be followed up. The purpose of this study is to validate the ultrasound (US)-guided vacuum-assisted breast biopsy system (Mammotome) for diagnosis and minimally invasive excision of IP.


METHODS
Six women with breast cystic-solid lesions without nipple discharge underwent B-US-guided 8-gauge Mammotome biopsy. Interval US surveillance was performed at a median time of 7 months (range 5-12 months).


RESULTS
All lesions were removed accurately and thoroughly with satisfactory cosmetic outcomes. All of them were histologically diagnosed as IP. No clinically significant hematoma developed.


CONCLUSIONS
The US-guided 8-gauge Mammotome biopsy provides an accurate pathologic diagnosis and successful complete excision of cystic-solid breast lesions. This technique appears to be an alternative to surgical biopsy in IP patients without nipple discharge.
Department of General Surgery, Changhai Hospital, Second Military Medical University, 200433 Shanghai, China. huweicj@163.com
Hu
H
Wei
Fan
F
Jiayi
Zhang
Z
Qinping
Shi
S
Junyi
Shen
S
Yuan
Li
L
Li
Su
S
Dongwei
Qing
Q
Liying
D000328:Adult; D001706:Biopsy / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D018300:Papilloma, Intraductal / Q000473:pathology* / Q000601:surgery*; D016217:Ultrasonography, Mammary; D014618:Vacuum