Potential role of statin therapy in heart failure, atrial fibrillation and aortic stenosis.
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, or statins, are widely prescribed throughout the world, and considerable evidence has indicated their powerful effects in ischemic forms of cardiovascular disease. Recently, several trials have demonstrated that statins have pleiotropic effects beyond their lipid-lowering capacities. These findings may play a role in the use of statins to manage forms of cardiovascular disease that may or may not have an ischemic etiology: congestive heart failure, atrial fibrillation and aortic stenosis.
Nagamia
Sameer
S
Emory University School of Medicine, Division of Cardiology, In Vascular Therapeutics, & Atlanta Vascular Research Foundation, 69 Jesse Hill Drive SE, C247 Atlanta, GA 30303, USA. sameer.nagamia@invasc.net
Thoenes
Martin
M
Khan
Qamar A
QA
Pandian
Anbu
A
Khan
Bobby V
BV