Comparison of the effect of tamoxifen on endometrial thickness in women with thin endometrium (<7mm) undergoing ovulation induction with clomiphene citrate.
Infertile women undergoing ovulation induction (OI) with clomiphene citrate (CC) who have adequate follicular recruitment and an endometrial thickness of <7 mm as determined by transvaginal sonography in the late follicular phase were switched to tamoxifen for OI in a subsequent cycle. A comparison between the endometrial thickness on CC and tamoxifen was made with by paired analysis. For women undergoing OI with CC who have adequate follicular recruitment and thin endometrium (<7 mm), switching to tamoxifen in subsequent cycles improves endometrial thickness.
Department of Obstetrics and Gynecology, Bethesda Hospital, Cincinnati, OH 45242, USA.
Kasey
K
Reynolds
Jane
J
Khoury
James
J
Sosnowski
Jennifer
J
Thie
Glen
G
Hofmann
D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use*; D004717:Endometrium / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology*; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D005498:Follicular Phase / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007247:Infertility, Female / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D009929:Organ Size / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods*; D012189:Retrospective Studies; D020845:Selective Estrogen Receptor Modulators / Q000494:pharmacology; D013629:Tamoxifen / Q000494:pharmacology*; D014463:Ultrasonography
D005300:Fertility Agents, Female; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen; D002996:Clomiphene