[Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation].
Hepatitis A is generally known as a mild, self-limiting disease of the liver, but in rare instances it can progress to fulminant hepatitis, which may require liver transplantation for recovery. Such cases are known to be related to old age and underlying liver disease. We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (>/=39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis.
Oh
Se Hoon
SH
Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
Lee
Joon Hyoek
JH
Hwang
Ji Won
JW
Kim
Hye Young
HY
Lee
Chang Hoon
CH
Gwak
Geum Youn
GY
Choi
Moon Seok
MS
Koh
Kwang Chul
KC
Paik
Seung Woon
SW
Yoo
Byung Chul
BC
D058186:Acute Kidney Injury / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D000367:Age Factors; D005260:Female; D006505:Hepatitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis*; D006529:Hepatomegaly / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000209:etiology; D016031:Liver Transplantation; D008297:Male; D014057:Tomography, X-Ray Computed