Distribution and phylogeny of light-oxygen-voltage-blue-light-signaling proteins in the three kingdoms of life.
Plants and fungi respond to environmental light stimuli via the action of different photoreceptor modules. One such class, responding to the blue region of light, is constituted by photoreceptors containing so-called light-oxygen-voltage (LOV) domains as sensor modules. Four major LOV families are currently identified in eukaryotes: (i) the plant phototropins, regulating various physiological effects such as phototropism, chloroplast relocation, and stomatal opening; (ii) the aureochromes, mediating photomorphogenesis in photosynthetic stramenopile algae; (iii) the plant circadian photoreceptors of the zeitlupe (ZTL)/adagio (ADO)/flavin-binding Kelch repeat F-box protein 1 (FKF1) family; and (iv) the fungal circadian photoreceptors white-collar 1 (WC-1). Blue-light-sensitive LOV signaling modules are also widespread throughout the prokaryotic world, and physiological responses mediated by bacterial LOV photoreceptors were recently reported. Thus, the question arises as to the evolutionary relationship between the pro- and eukaryotic LOV photoreceptor systems. We used Bayesian and maximum-likelihood tree reconstruction methods to infer evolutionary scenarios that might have led to the widespread appearance of LOV domains among the pro- and eukaryotes. The phylogenetic study presented here suggests a bacterial origin for the LOV domains of the four major eukaryotic LOV photoreceptor families, whereas the LOV sensor domains were most likely recruited from the bacteria in the course of plastid and mitochondrial endosymbiosis.
Institut für Molekulare Enzymtechnologie, Heinrich-Heine Universität Düsseldorf, Forschungszentrum Jülich, Jülich, Germany. u.krauss@fz-juelich.de
Ulrich
U
Krauss
Bui Quang
BQ
Minh
Aba
A
Losi
Wolfgang
W
Gärtner
Thorsten
T
Eggert
Arndt
A
von Haeseler
Karl-Erich
KE
Jaeger
D020418:Algal Proteins / Q000235:genetics; D029681:Arabidopsis Proteins / Q000145:classification / Q000235:genetics; D001419:Bacteria / Q000145:classification*; D001426:Bacterial Proteins / Q000235:genetics; D001499:Bayes Theorem; D004268:DNA-Binding Proteins / Q000145:classification / Q000235:genetics; D005656:Fungal Proteins / Q000145:classification / Q000235:genetics; D005658:Fungi / Q000145:classification*; D016013:Likelihood Functions; D056949:Phototropins / Q000145:classification / Q000235:genetics; D010802:Phylogeny; D010940:Plant Proteins / Q000235:genetics; D010944:Plants / Q000145:classification*; D014157:Transcription Factors / Q000145:classification / Q000235:genetics
D020418:Algal Proteins; D029681:Arabidopsis Proteins; D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C410504:FKF1 protein, Arabidopsis; D005656:Fungal Proteins; D056949:Phototropins; D010940:Plant Proteins; D014157:Transcription Factors; C410503:ZTL protein, Arabidopsis; C105589:wc-1 protein, Neurospora crassa