Early experience with a simplified technique for transcatheter closure of the patent foramen ovale.
BACKGROUND
Although generally safe, transcatheter patent foramen ovale (PFO) closure typically involves catheter exchanges and manipulations within the left atrium (LA) that may result in complications. We describe the development of a simplified technique for PFO closure, further to modification of our earlier approaches.


METHODS
Early in our experience, LA angiography and/or balloon sizing of the PFO was routine prior to device closure. Subsequently, the simplified technique described herein became our standard approach. We reviewed immediate and medium term results in 27 consecutive patients who underwent closure in a 24-month time frame.


RESULTS
All procedures used general anaesthesia, TEE guidance and CardioSEAL septal occluder. Device delivery was successful in all patients. The median fluoroscopy time was significantly shorter with the simplified technique (median difference 6.7min, p<0.05) with a 98.3% median confidence interval (4.5, 19.9min). There were four complications, all occurring in the early group of patients. There have been no recurrent neurological events or device related adverse events on medium term follow-up.


CONCLUSIONS
Successful transcatheter PFO closure is feasible without LA angiography or catheter-based balloon sizing, utilising echocardiographic guidance for device selection and placement. Simplification of PFO closure technique could potentially decrease complications and shorten fluoroscopy times.
University of Nebraska/Creighton University Joint Division of Pediatric Cardiology, Children's Hospital and Medical center, Omaha, United States.
Shelby
S
Kutty
David G
DG
Nykanen
Evan M
EM
Zahn
D000293:Adolescent; D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization / Q000295:instrumentation*; D016001:Confidence Intervals; D005240:Feasibility Studies; D005260:Female; D054092:Foramen Ovale, Patent / Q000628:therapy*; D006325:Heart Atria; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D055989:Septal Occluder Device; D013997:Time Factors; D055815:Young Adult