Layered carbon nanotube-polyelectrolyte electrodes outperform traditional neural interface materials.
The safety, function, and longevity of implantable neuroprosthetic and cardiostimulating electrodes depend heavily on the electrical properties of the electrode-tissue interface, which in many cases requires substantial improvement. While different variations of carbon nanotube materials have been shown to be suitable for neural excitation, it is critical to evaluate them versus other materials used for bioelectrical interfacing, which have not been done in any study performed so far despite strong interest to this area. In this study, we carried out this evaluation and found that composite multiwalled carbon nanotube-polyelectrolyte (MWNT-PE) multilayer electrodes substantially outperform in one way or the other state-of-the-art neural interface materials available today, namely activated electrochemically deposited iridium oxide (IrOx) and poly(3,4-ethylenedioxythiophene) (PEDOT). Our findings provide the concrete experimental proof to the much discussed possibility that carbon nanotube composites can serve as excellent new material for neural interfacing with a strong possibility to lead to a new generation of implantable electrodes.
Jan
Edward
E
Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Hendricks
Jeffrey L
JL
Husaini
Vincent
V
Richardson-Burns
Sarah M
SM
Sereno
Andrew
A
Martin
David C
DC
Kotov
Nicholas A
NA
D000200:Action Potentials / Q000502:physiology*; D003460:Crystallization / Q000379:methods; D004553:Electric Conductivity; D004573:Electrolytes / Q000737:chemistry*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008839:Microelectrodes; D008968:Molecular Conformation; D036103:Nanotechnology / Q000295:instrumentation*; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure*; D009474:Neurons / Q000502:physiology*; D010316:Particle Size; D013499:Surface Properties
D004573:Electrolytes; D046911:Macromolecular Substances; D037742:Nanotubes, Carbon