Four new lignans from Viburnum foetidum var. foedidum.
The 70% aqueous acetone extract of the aerial part of Viburnum foetidum var. foedidum afforded four new lignans (1-4) together with six known ones. The structures of the four new compounds were elucidated on the basis of 1D (dimensional), 2D-NMR, and mass spectral analysis. The structure of compound 1, with a novel spirocyclic moiety, was also confirmed by X-ray diffraction analysis. Compounds 1-10 were evaluated for their cytotoxic activity. However, none of the compounds showed significant cytotoxic activity.
Chen
Xuan-Qin
XQ
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650204, PR China.
Li
Yan
Y
He
Juan
J
Wang
Kou
K
Li
Ming-Ming
MM
Pan
Zheng-Hong
ZH
Peng
Li-Yan
LY
Cheng
Xiao
X
Zhao
Qin-Shi
QS
D018360:Crystallography, X-Ray; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D027925:Viburnum / Q000737:chemistry*
D017705:Lignans; D010936:Plant Extracts