Influence of Trypanosoma evansi in blood, plasma, and brain cholinesterase of experimentally infected cats.
Changes in blood, plasma and brain cholinesterase activities in Trypanosoma evansi-infected cats were investigated. Seven animals were infected with 10(8) trypomastigote forms each and six were used as control. Animals were monitored for 56 days by examining daily blood smears. Blood samples were collected at days 28 and 56 post-inoculation to determine the activity of acetylcholinesterase (AChE) in blood and the activity of butyrylcholinesterase (BChE) in plasma. AChE was also evaluated in total brain. The activity of AChE in blood and brain, and the activity of BChE in plasma significantly reduced in the infected cats. Therefore, the infection by T. evansi influenced cholinesterases of felines indicating changes in the responses of the cholinergic system.
Da Silva
A S
AS
Universidade Federal de Santa Maria, Faixa de Camobi, Km 9, Campus Universitário, 97105-900 Santa Maria, RS, Brazil. aleksandro_ss@yahoo.com.br
Spanevello
R
R
Stefanello
N
N
Wolkmer
P
P
Costa
M M
MM
Zanette
R A
RA
Lopes
S T A
ST
Santurio
J M
JM
Schetinger
M R C
MR
Monteiro
S G
SG
D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology*; D002371:Cat Diseases / Q000097:blood / Q000201:enzymology* / Q000469:parasitology; D002415:Cats; D005260:Female; D014345:Trypanosoma / Q000302:isolation & purification*; D014352:Trypanosomiasis / Q000097:blood / Q000201:enzymology / Q000662:veterinary*
D000110:Acetylcholinesterase