Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: synthesis of 2-alkynyl-4-arylquinolines.
A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.
Reddy
Ellanki Amarender
EA
Dr. Reddy's Laboratories Limited, Bollaram Road, Miyapur, Hyderabad 500049, Andhra Pradesh, India.
Islam
Aminul
A
Mukkanti
K
K
Bandameedi
Venkanna
V
Bhowmik
Dipal Ranjan
DR
Pal
Manojit
M