A systematic review of intracranial chondrosarcoma and survival.
Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.
Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, California 94143, USA.
Orin G
OG
Bloch
Brian J
BJ
Jian
Isaac
I
Yang
Seunggu J
SJ
Han
Derick
D
Aranda
Brian J
BJ
Ahn
Andrew T
AT
Parsa
D016009:Chi-Square Distribution; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000401:mortality* / Q000628:therapy; D016208:Databases, Factual / Q000706:statistics & numerical data; D006801:Humans; D008137:Longitudinal Studies; D011379:Prognosis; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000401:mortality* / Q000628:therapy; D015996:Survival Rate