Cross-coupling of alkenyl/aryl carboxylates with Grignard reagent via Fe-catalyzed C-O bond activation.
Iron-catalyzed cross-coupling of alkenyl/aryl carboxylates with primary alkyl Grignard reagent was described. This reaction brought a new family of electrophiles to iron catalysis. The combination of an inexpensive carboxylate electrophile and an iron catalyst would generate ample advantages.
Li
Bi-Jie
BJ
Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
Xu
Li
L
Wu
Zhen-Hua
ZH
Guan
Bing-Tao
BT
Sun
Chang-Liang
CL
Wang
Bi-Qin
BQ
Shi
Zhang-Jie
ZJ
D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D007202:Indicators and Reagents / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
D000475:Alkenes; D002264:Carboxylic Acids; D007202:Indicators and Reagents; D002244:Carbon; D007501:Iron; D010100:Oxygen