Constriction infection.
Chronic constrictive pericarditis (CCP) is a clinical syndrome caused by compression of the heart due to a thickened or rigid pericardium. In the affluent West, the majority of cases of CCP are neither tuberculous nor calcific. In an American cohort undergoing pericardectomy for the condition, only 27% had calcification and under 10% had TB [1]. As a result, pericardial calcification (PC) as a marker of CCP has become neglected. We present a 48-year-old male admitted with atrial flutter, acute chest infection and signs of right heart congestion. PC was documented one year previously on a non-contrast CT chest. On this occasion, cardiac catheterisation confirmed hemodynamically significant CCP and cardiac magnetic resonance (cMR) study showed contiguous mass lesions in the pericardium, compression of the right ventricle, enlargement of the right atrium, hepatic enlargement and a pneumonic process in the left lung. He was commenced on antibiotics and anti-tuberculous therapy with a diagnosis of bacterial super-infection of tuberculous CCP. This was confirmed at pericardectomy along with an infected fistula into the left lung. Any finding of PC should be followed up with a thorough haemodynamic and anatomical assessment using any of a wide range of non-invasive imaging modalities.
Purvis
J A
JA
Cardiac Unit, Altnagelvin Hospital, Western HSC Trust, Derry, Northern Ireland, UK. john.purvis@btinternet.com
Roberts
M
M
Harbinson
M T
MT
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D002114:Calcinosis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D006328:Cardiac Catheterization; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010492:Pericardiectomy; D010494:Pericarditis, Constrictive / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D010495:Pericarditis, Tuberculous / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D015163:Superinfection; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D002317:Cardiovascular Agents