New caloporoside derivatives and their inhibition of fungal spore germination.
In our ongoing screening culture fluid extracts of Gloeoporus (Caloporus) dichrous strain 83065 inhibited the germination of Magnaporthe grisea and Fusarium graminearum spores. While isolating the active metabolites two new caloporosides, caloporoside G and caloporoside H, in addition to the known caloporoside derivatives F-16438G, caloporoside A, and 2-hydroxy-6-(16-hydroxyheptadecyl)benzoic acid were obtained.
Schüffler
Anja
A
University of Kaiserslautern, Paul-Ehrlich-Str. 23, D-67663 Kaiserslautern, Germany.
Liermann
Johannes C
JC
Kolshorn
Heinz
H
Opatz
Till
T
Anke
Timm
T
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D019169:Jurkat Cells / Q000187:drug effects; D007939:Leukemia L1210 / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D008358:Mannose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D051379:Mice; D012459:Salicylates / Q000737:chemistry / Q000494:pharmacology*; D013172:Spores, Fungal / Q000187:drug effects / Q000502:physiology*; D010738:Type C Phospholipases / Q000037:antagonists & inhibitors
D000935:Antifungal Agents; D012459:Salicylates; C091111:caloporoside; D010738:Type C Phospholipases; D008358:Mannose