Clinical effects of hypertension on the mortality of patients with acute myocardial infarction.
The incidence of ischemic heart disease has been increased rapidly in Korea. However, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class > or =III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade < or =2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
Kwangju Christian Hospital, Gwangju, Korea.
Dong Goo
DG
Kang
Myung Ho
MH
Jeong
Yongkeun
Y
Ahn
Shung Chull
SC
Chae
Seung Ho
SH
Hur
Taek Jong
TJ
Hong
Young Jo
YJ
Kim
In Whan
IW
Seong
Jei Keon
JK
Chae
Jay Young
JY
Rhew
In Ho
IH
Chae
Myeong Chan
MC
Cho
Jang Ho
JH
Bae
Seung Woon
SW
Rha
Chong Jin
CJ
Kim
Yang Soo
YS
Jang
Junghan
J
Yoon
Ki Bae
KB
Seung
Seung Jung
SJ
Park
D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D002561:Cerebrovascular Disorders / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D005260:Female; D006333:Heart Failure / Q000209:etiology; D017052:Hospital Mortality; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality* / Q000628:therapy; D016491:Peripheral Vascular Diseases / Q000209:etiology; D011237:Predictive Value of Tests; D012042:Registries; D012737:Sex Factors