Fatal hemorrhage due to thrombosis and rupture of the portal vein and hepatic artery.
Portal vein thrombosis is a fairly common clinical condition that is usually not fatal but may give rise to serious complications. We report the case of a woman who was always in good health until the age of 50, when she developed acute gastroenterocolitis with inflammation of the portal vein (pylephlebitis or septic portal thrombophlebitis), resulting in thrombus formation, rupture of the vascular wall and exsanguination. At autopsy, no signs of thrombosis or inflammation were found elsewhere in the body and there was no evidence of any other disease or abnormality. Pylephlebitis may occur following intra-abdominal sepsis from any source. It is a rare condition that carries a high mortality. Rupture of the inflamed portal vein and possibly the adjacent artery is an extremely rare complication.
Department of Gastroenterology, Division of Internal Medicine, University Medical Center Ljubljana, Slovenia. ivan.ferkolj@kclj.si
Ivan
I
Ferkolj
Jadranka
J
Vrh-Jermancic
Borut
B
Stabuc
D017809:Fatal Outcome; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006499:Hepatic Artery / Q000293:injuries*; D006801:Humans; D008875:Middle Aged; D011169:Portal Vein / Q000293:injuries*; D012421:Rupture / Q000150:complications / Q000175:diagnosis; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*