Evidence that active transmission of porcine cysticercosis occurs in Venezuela.
There is a paucity of quantitative data on the status of porcine cysticercosis in Venezuela, information which is essential for understanding the level of disease transmission. This study was, therefore, conducted in a typical small rural community in Yaracuy State, Venezuela, where previous cases of human Taenia solium taeniasis/cysticercosis had been reported and where the free-ranging pig management practices and the lack of rudimentary sanitary facilities indicated an obvious risk for transmission of the disease. Serum samples from 52 village pigs were screened by enzyme-linked immunosorbent assays for anti-cysticercal antibodies (Ab-ELISA), using T. solium cyst fluid as the antigen and the HP10, monoclonal antibody-based, antigen trapping ELISA for parasite antigen (HP10 Ag-ELISA). Significantly, a high proportion of the animals (65.4% for the Ab-ELISA and 42.3% for the HP10 Ag-ELISA) were sero-positive. Five of the pigs, which were selected on that basis of positive tongue palpation, were killed for autopsy, and large numbers of viable cysticerci were found in the carcases. This unequivocal documentation of porcine cysticercosis in Venezuelan pigs presents clear evidence that T. solium is actively transmitted in Venezuela. Further detailed studies and implementation of appropriate control measures are therefore indicated.
Instituto de Investigaciones Biomédicas Facultad de Ciencias de Salud, Sede Aragua, Universidad de Carabobo, Final C/Cecilio Acosta, Av. Las Delicias, Urb. La Rinconada, Maracay, Estado Aragua P O Box 2351, Maracay, Venezuela. milacortez3@yahoo.com
Maria M
MM
Cortez Alcobedes
Gonzalo
G
Boggio
Ma de Lourdes
Mde L
Guerra
Magda Rodríguez
MR
de Gavidia
Glenda C
GC
Rojas Reyes
Elizabeth
E
Ferrer
Maria
M
Lares
Yenny
Y
Alviarez
Leslie J S
LJ
Harrison
R Michael E
RM
Parkhouse
D000822:Animal Husbandry; D000818:Animals; D003551:Cysticercosis / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D016036:Seroepidemiologic Studies; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000469:parasitology / Q000635:transmission*; D014687:Venezuela / Q000453:epidemiology