Characterization of plasmids encoding CMY-2 AmpC beta-lactamases from Escherichia coli in Canadian intensive care units.
The dissemination of CMY-2 AmpC beta-lactamases among Escherichia coli in Canadian intensive care units occurs through a combination of clonal spread of virulent strains and the horizontal transfer of genetically similar IncI1, IncA/C, and IncK/B plasmids.
Baudry
Patricia J
PJ
Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada R3A 1R9. trishbaudry@hotmail.com
Mataseje
Laura
L
Zhanel
George G
GG
Hoban
Daryl J
DJ
Mulvey
Michael R
MR
D001426:Bacterial Proteins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D002170:Canada; D016000:Cluster Analysis; D003428:Cross Infection / Q000382:microbiology*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000032:analysis*; D001618:beta-Lactamases / Q000235:genetics*
D001426:Bacterial Proteins; D004269:DNA, Bacterial; C048795:AmpC beta-lactamases; D001618:beta-Lactamases