[Two en-kaurene diterpenoids from Tibetan medicine Caryopteris toroetii].
OBJECTIVE
To study the chemical constituents of Tibetan medicine Caryopteris toroetii.


METHODS
The crude drug was extracted with 95% EtOH and isolated by repeated chromatographic methods. The structures of the isolated compounds were elucidated on the basis of spectral analysis.


RESULTS
Two en-kaurene diterpenoid compounds: oridonin (1) and nodosin (2), were obtained from C. toroetii and their 1H and 13C-NMR data in CD3OD were reported for the first time.


CONCLUSIONS
The en-kaurene diterpenoid compounds were obtained from genus Caryopteris for the first time.
Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. qsyang96@163.com
Sheng
S
Que
Yuying
Y
Zhao
Yong
Y
Zhou
Qingying
Q
Zhang
D045786:Diterpenes, Kaurane / Q000737:chemistry* / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D019686:Lamiaceae / Q000737:chemistry*; D038861:Medicine, Tibetan Traditional
D045786:Diterpenes, Kaurane; D004365:Drugs, Chinese Herbal