Synergistic effects of ACE (I/D) and ApoE (HhaI) gene polymorphisms among the adult Asian Indians with and without metabolic syndrome.
A total of 350 (184 males and 166 females) adults participated in the study. A sample of 138 individuals was selected randomly for genotyping. The synergistic effect of ACE (I/D) and ApoE (HhaI) on metabolic syndrome (MS) showed that individuals with e4/4+D/D combination had the highest occurrence of metabolic abnormalities.
Department of Anthropology, Sree Chaitanya College, West Bengal, India.
Mithun
M
Das
Susil
S
Pal
Arnab
A
Ghosh
D000328:Adult; D001057:Apolipoproteins E / Q000235:genetics*; D044466:Asian People / Q000235:genetics; D001794:Blood Pressure; D015992:Body Mass Index; D004247:DNA / Q000097:blood / Q000235:genetics / Q000302:isolation & purification; D050171:Dyslipidemias / Q000453:epidemiology / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007194:India; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000201:enzymology / Q000235:genetics*; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic; D049629:Waist-Hip Ratio
D001057:Apolipoproteins E; D008055:Lipids; D004247:DNA; D007703:Peptidyl-Dipeptidase A