1H-NMR spectroscopic study of the effect of aging vascular prostheses made of poly(ethylene terephthalate) on the macromolecular weight.
Trichloroacetyl isocyanate reacts rapidly and quantitatively with both acid and hydroxyl chain ends to form derivatives that can be readily determined by (1)H-NMR spectroscopy. This method provides a convenient mean for characterization of polyethylene terephthalate (PET) end-groups. The (1)H-NMR spectroscopy has been applied to describe the chemical aging of the PET vascular prostheses by determination of the hydroxyl and carboxyl end-group concentrations and therefore the macromolecular weight. To validate (1)H-NMR results, we used chemical titration of the end-groups and classical viscosimetric method as complementary techniques. The analyses made on the explants of different lifetime demonstrated a significant deterioration compared with the virgin prostheses. A high degradation of macromolecular weight is observed. This phenomenon is explained by a random scission of the ester linkages.
Chaouch
W
W
Laboratoire de Physique et Mécanique Textile CNRS-UMR 7189, Université de Haute Alsace, 11 rue Alfred Werner, Mulhouse cedex 68093, France. walid.chaouch@uha.fr
Dieval
F
F
Le Nouen
D
D
Defoin
A
A
Chakfe
N
N
Durand
B
B
D001807:Blood Vessel Prosthesis; D006801:Humans; D006868:Hydrolysis; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008422:Materials Testing; D008956:Models, Chemical; D008970:Molecular Weight; D011093:Polyethylene Terephthalates / Q000737:chemistry*; D011475:Prosthesis Failure; D013997:Time Factors; D014783:Viscosity
D046911:Macromolecular Substances; D011093:Polyethylene Terephthalates