Synthesis of polysubstituted tetrahydrofurans via Pd-catalyzed carboetherification reactions.
Pd-catalyzed carboetherifications of 1-, 2-, or 3-substituted γ-hydroxy internal alkenes afford tetrahydrofuran products bearing three stereocenters in good yield with moderate to good stereoselectivity.
Hay
Michael B
MB
University of Michigan, Department of Chemistry, 930 N. University Ave, Ann Arbor, Michigan, 48109-1055.
Wolfe
John P
JP