Chitosan may decrease serum valproate and increase the risk of seizure reappearance.
Unit of Muscular and Neurodegenerative Diseases, G Gaslini Institute, University of Genova, Genova. pstriano@email.it
Pasquale
P
Striano
Federico
F
Zara
Carlo
C
Minetti
Salvatore
S
Striano
D000328:Adult; D019440:Anti-Obesity Agents / Q000009:adverse effects*; D000927:Anticonvulsants / Q000097:blood / Q000627:therapeutic use*; D048271:Chitosan / Q000009:adverse effects*; D019587:Dietary Supplements / Q000009:adverse effects*; D004347:Drug Interactions; D004829:Epilepsy, Generalized / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D010634:Phenobarbital / Q000097:blood / Q000627:therapeutic use; D012008:Recurrence; D012307:Risk Factors; D014635:Valproic Acid / Q000097:blood / Q000627:therapeutic use*
D019440:Anti-Obesity Agents; D000927:Anticonvulsants; D014635:Valproic Acid; D048271:Chitosan; D010634:Phenobarbital