[Dependence of atropin-induced amnesia fluctuations on the state of pineal gland].
Atropin produces weakening of the memory on the model of passive avoidance reaction in rats, the effect being more pronounced in evening hours. The drug effect is increased in pinealectomized animals and attenuated by the pineal hormone melatonin, also differently in daytime.
Arushanian
E B
EB
Beĭer
E V
EV
skorniakoc
A A
AA
D000647:Amnesia / Q000139:chemically induced / Q000378:metabolism* / Q000503:physiopathology; D000818:Animals; D001285:Atropine / Q000009:adverse effects* / Q000494:pharmacology; D001362:Avoidance Learning / Q000187:drug effects*; D001522:Behavior, Animal / Q000187:drug effects; D002492:Central Nervous System Depressants / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D008550:Melatonin / Q000378:metabolism* / Q000494:pharmacology; D010276:Parasympatholytics / Q000009:adverse effects* / Q000494:pharmacology; D010870:Pineal Gland / Q000378:metabolism* / Q000503:physiopathology; D051381:Rats
D002492:Central Nervous System Depressants; D010276:Parasympatholytics; D001285:Atropine; D008550:Melatonin