[Clinical experience of successful management of a human case with A/H5N1 infection in Hunan Province].
OBJECTIVE
To study the clinical features and successful management of a survived human case with A/H5N1 infection.


METHODS
The data of a confirmed case of human case with A/H5N1 infection in Hunan province were collected and analyzed.


RESULTS
This patient with A/H5N1 infection in Hunan province was confirmed by reverse-transcription polymerase chain reaction (RT-PCR) for A/H5N1 in airway secretions. The main clinical presentations included fever, cough and dyspnea. An extensive pulmonary infiltration developed quickly, followed by multi-organ dysfunction. Early administration of oseltamivir, early protection of organ function and extensive support were effective for the cure of the disease in this case.


CONCLUSIONS
Early administration of oseltamivir, early protection of organ function and adequate support therapy may be useful for the treatment of human A/H5N1 infection.
ICU, Xiangya Hospital of Central Southern University, Changsha 410008, China.
Shuang-ping
SP
Zhao
Zhen-huan
ZH
Hai
De-ming
DM
Tan
Gui-lin
GL
Xiao
Qi-hua
QH
Gu
Min
M
Li
Xiang-min
XM
Li
Cheng-ping
CP
Hu
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D002681:China; D005260:Female; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype; D007251:Influenza, Human / Q000628:therapy* / Q000821:virology; D009102:Multiple Organ Failure / Q000209:etiology / Q000628:therapy*; D053139:Oseltamivir / Q000627:therapeutic use; D016896:Treatment Outcome
D000998:Antiviral Agents; D053139:Oseltamivir