Physicochemical properties and antioxidant activities of luteolin-phospholipid complex.
A luteolin and phospholipid complex was prepared to improve the lipophilic properties of luteolin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD) and differential scanning calorimetry (DSC). The results showed that luteolin and phospholipid in the complex were joined by non-covalent-bonds and did not form a new compound. It was found that the complex was an effective scavenger of DPPH radicals, with an IC(50) value of 28.33 microg/mL. In the Rancimat antioxidant test using lard oil as substrate, the complex also showed the strong antioxidant activity.
Xu
Keyong
K
College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, China. kyxky@163.com
Liu
Benguo
B
Ma
Yuxiang
Y
Du
Jiquan
J
Li
Guanglei
G
Gao
Han
H
Zhang
Yuan
Y
Ning
Zhengxiang
Z
D000975:Antioxidants / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000378:metabolism; D002152:Calorimetry, Differential Scanning; D016166:Free Radical Scavengers / Q000494:pharmacology; D047311:Luteolin / Q000737:chemistry* / Q000494:pharmacology*; D010743:Phospholipids / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010743:Phospholipids; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D047311:Luteolin