Rosai-Dorfman disease of the lung.
Rosai-Dorfman disease is a rare disorder which seems to involve not only the lymph nodes but most other organs of the body. The case history is presented of a woman who was thought to have atypical carcinoma of the lung but in whom a diagnosis of Rosai-Dorfman disease was eventually made following a range of investigations including CT scans, positron emission tomography (PET) and histological analysis of open lung biopsy specimens. She remains well with no further progression of the disease without treatment. Rosai-Dorfman disease can mimic lung carcinoma and shows increased activity on PET scanning, so histological confirmation should be sought in all cases.
Ali
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Department of Respiratory Medicine, Good Hope Hospital, Heart of England NHS Trust, Sutton Coldfield, West Midlands B75 7RR, UK. asad935@yahoo.co.uk
Mackay
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D000328:Adult; D001706:Biopsy / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis*; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed