Lipoedema: from clinical presentation to therapy. A review of the literature.
Lipoedema is an infrequently recognized disorder in women. Lipoedema is characterized by bilateral enlargement of the legs due to abnormal depositions of subcutaneous fat associated with often mild oedema. There is substantial variability in disease severity. The diagnosis should be made as early as possible to prevent complications of the disorder, which is associated with increasing functional and cosmetic morbidity. This review describes clinical manifestations, pathogenesis, technical investigations, management and therapies of lipoedema, with the aim of optimizing management and care of patients with lipoedema.
Langendoen
S I
SI
Department of Dermatology, Erasmus Medical Center, 3000 CA Rotterdam, the Netherlands. s.langendoen@erasmusmc.nl
Habbema
L
L
Nijsten
T E C
TE
Neumann
H A M
HA
D003240:Connective Tissue Diseases / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D003937:Diagnosis, Differential; D004487:Edema / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000473:pathology*; D008297:Male; D050151:Subcutaneous Fat / Q000473:pathology*