Preliminary report: a serious link between adiponectin levels and metabolic syndrome in a Korean nondiabetic population.
This large-scale cross-sectional investigation highlights the relationships between adiponectin levels and a number of metabolic syndrome components in a nondiabetic Korean population (N = 6634). In a multivariate logistic regression model, after adjustment for age, homeostasis model assessment of insulin resistance, body mass index, smoking history, C-reactive protein, and low-density lipoprotein cholesterol, adiponectin levels were inversely related with metabolic syndrome in men and women (P < .05). Adiponectin level was found to be a significant contributor to metabolic syndrome. Our findings suggest that adiponectin is an important biomarker even in a nondiabetic population at high risk of metabolic syndrome.
Koh
Sang-Back
SB
Department of Preventive Medicine, Wonju College of Medicine, Yonsei University, Wonju 220-710, South Korea.
Park
Jong-Ku
JK
Yoon
Jin-Ha
JH
Chang
Sei-Jin
SJ
Oh
Sung-Soo
SS
Kim
Jang-Young
JY
Ryu
So-Yeon
SY
Kim
Ki-Soon
KS
Lee
Tae-Yong
TY
You
Joshua Sung H
JS
D052242:Adiponectin / Q000097:blood*; D000368:Aged; D000886:Anthropometry; D015415:Biomarkers; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D015331:Cohort Studies; D005260:Female; D006706:Homeostasis; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology*; D008875:Middle Aged; D010641:Phenotype; D056910:Republic of Korea / Q000453:epidemiology
D052242:Adiponectin; D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids