Primary iris stromal cyst with rapid growth.
OBJECTIVE
To describe the clinical features and the surgical management of primary iris stromal cyst with rapid growth.


METHODS
A 14-year-old Chinese-Mongolian girl was referred to us with a 1-month history of obstructed vision and photophobia. On an examination, a semitransparent cyst with a densely pigmented posterior wall was revealed in the anterior chamber of the left eye. The information regarding the location and extent of the cyst was further analyzed by anterior segment optical coherence tomography and ultrasound biomicroscopy. It arose within the iris stroma, measuring 7.52 x 3.60 mm. Blood vessels on the surface of the lesion were revealed by iris angiography. There was no history of amniocentesis, birth trauma, antecedent ocular injury, or maternal illness during gestation. The diagnosis of primary iris stromal cyst was made. A combination of needle aspiration, piecemeal resection of cyst wall, cryotherapy, and argon laser photocoagulation with overlapped spots was used.


RESULTS
Histopathology of the cyst wall revealed nonkeratinized, multilayered, stratified squamous epithelium with clusters of goblet cells. Complete resolution of the cyst was successfully achieved. The visual acuity improved to 20/25 from counting fingers. At 6 months of follow-up, there was no recurrence.


CONCLUSIONS
Complete eradication and devitalization of any remaining epithelial cells are the key factors for preventing recurrence and diffuse epithelialization of the anterior chamber.
Xiao
Yang
Y
Department of Ophthalmology, Beijing Chaoyang Hospital (West Campus), Affiliate of Capital Medical University, Beijing, People's Republic of China. xiaoyangmd@yahoo.com.cn
Wang
Yu-Hong
YH
Niu
Gai-Ling
GL
Gao
Min
M
D000293:Adolescent; D044466:Asian People; D017679:Cryotherapy / Q000379:methods; D003560:Cysts / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology* / Q000601:surgery; D018450:Disease Progression; D004848:Epithelium / Q000473:pathology; D005260:Female; D020397:Goblet Cells / Q000473:pathology; D006801:Humans; D007499:Iris Diseases / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology* / Q000628:therapy; D033401:Microscopy, Acoustic; D013256:Steroids / Q000627:therapeutic use; D013396:Suction; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity
D013256:Steroids