Arylation of benzo-fused 1,4-quinones by the addition of boronic acids under dicationic Pd(II)-catalysis.
The first examples of the direct arylation of benzo-fused 1,4-quinones by the dicationic Pd(II)-catalyzed addition of arylboronic acids are reported. The addition reaction is carried out under very mild conditions (dioxane-H(2)O, rt, open air atmosphere) and is tolerant of free OH groups. In addition, the reaction shows high regioselectivity when using nonsymmetrical quinones as starting materials.
Molina
María Teresa
MT
Instituto de Química Médica (CSIC), C/Juan de la Cierva, 3, 28006-Madrid, Spain. mtmolina@iqm.csic.es
Navarro
Cristina
C
Moreno
Ana
A
Csákÿ
Aurelio G
AG
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011809:Quinones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D001897:Boronic Acids; D011809:Quinones; D010165:Palladium