Study on the changes of thrombosis-associated factors in patients with coronary heart disease of turbidity-phlegm blocking syndrome.
OBJECTIVE
To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism.


METHODS
Plasma levels of thrombosis-associated factors, including Von Willebrand factor: (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared.


RESULTS
Levels of the three factors were increased in all the CHD: patients, and were higher in TPB patients than in non-TPB patients (P<0.01 or P<0.05).


CONCLUSIONS
The TPB: syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in pre-thrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for thrombosis differentiation of TPB syndrome in CHD patients.
Wang
Yun-long
YL
Traditional Chinese Medicine College of Xinjiang Medical University, Urumiqi, China.
An
Dong-qing
DQ
Ma
Ning
N
Zhu
Meng
M
Sun
Hong-yan
HY
D016022:Case-Control Studies; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology*; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D013927:Thrombosis / Q000097:blood / Q000503:physiopathology*; D014841:von Willebrand Factor / Q000378:metabolism
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D014841:von Willebrand Factor; D005340:Fibrinogen