[Application of thermoplastic elastomer in hot-melt pressure sensitive adhesives for transtermal drug delivery].
Development of drug dosage forms to a great extent depends on the development of drug auxiliary materials. The development of a new type of polymeric drug auxiliary materials will bring on the developing of a novel dosage forms technology and a flood of new drug dosage forms. Thermoplastic elastomer is a new type of drug polymeric auxiliary materials, at present, which has a broad application in the field of hot-melt pressure sensitive adhesives. This review mainly discussed a new transtermal Chinese drug delivery system, including matrix composition of the formula, modified thermoplastic elastomer for hot-melt pressure sensitive adhesives and their development prospects in the traditional Chinese drug delivery system. It suggested that thermoplastic elastomer of hot-melt pressure sensitive adhesives has broad development prospects in the field of the transtermal drug delivery system for traditional Chinese medicine.
China Academy of Chinese Medicine Sciences Xiyuan Hospital, Beijing 100091, China.
Xiaoping
X
Yan
Rui
R
Zheng
Shijie
S
Guan
Bowen
B
Yi
D000269:Adhesives / Q000737:chemistry; D000277:Adjuvants, Pharmaceutic / Q000737:chemistry*; D000279:Administration, Cutaneous; D016503:Drug Delivery Systems / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D020724:Elastomers / Q000737:chemistry; D006801:Humans; D012869:Skin Absorption
D000269:Adhesives; D000277:Adjuvants, Pharmaceutic; D004365:Drugs, Chinese Herbal; D020724:Elastomers