An outbreak of highly pathogenic H5N1 avian influenza in Korea, 2008.
In spite of intensive surveillance programs for the control of HPAI, an outbreak of highly pathogenic avian influenza (HPAI) H5N1 in Korea in April 2008 caused serious damage to poultry farms, as did previous outbreaks in 2003/2004 and 2006/2007. Six viruses were selected from the Korean 2008 isolates for genetic analysis, and all eight gene segments from each of the influenza viruses were sequenced. A phylogenetic analysis showed that all of the viruses were of the same virus type and that the hemagglutinin (HA) gene was clustered with that of clade 2.3.2 viruses. However, the internal and neuraminidase (NA) genes were closely related to those of the clade 2.3.4 viruses (recent human and bird isolates from Southeast Asia).
Kim
Hye-Ryoung
HR
National Veterinary Research and Quarantine Service, 335 Joongangro Manangu Anyangsi, Gyeonggido 430-824, Republic of Korea. kimhr@nvrqs.go.kr
Park
Choi-Kyu
CK
Lee
Youn-Jeong
YJ
Woo
Gye-Hyeong
GH
Lee
Kyoung-Ki
KK
Oem
Jae-Ku
JK
Kim
Seong-Hee
SH
Jean
Young-Hwa
YH
Bae
Yu-Chan
YC
Yoon
Soon-Seek
SS
Roh
In-Soon
IS
Jeong
Ok-Mi
OM
Kim
Ha-Young
HY
Choi
Jeong-Soo
JS
Byun
Jae-Won
JW
Song
Yun-Kyung
YK
Kwon
Jun-Hun
JH
Joo
Yi-Seok
YS
D000818:Animals; D004196:Disease Outbreaks; D004372:Ducks; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D005585:Influenza in Birds / Q000453:epidemiology*; D007723:Korea / Q000453:epidemiology; D009439:Neuraminidase / Q000235:genetics; D016865:Reassortant Viruses
D009439:Neuraminidase