Constructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles.
As history has demonstrated, post-approval obstacles can impede a vaccine's use and potentially lead to its withdrawal. Addressing these potential obstacles when changes in a vaccine's technology can still be easily made may improve a vaccine's chances of success. Augmented vaccine target product profiles (TPPs) can help vaccine scientists better understand and anticipate these obstacles and galvanize conversations among various vaccine stakeholders (e.g., scientists, marketers, business development managers, policy makers, public health officials, health care workers, third party payors, etc.) earlier in a vaccine's development.
Lee
Bruce Y
BY
School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. BYL1@pitt.edu
Burke
Donald S
DS
D006801:Humans; D011358:Product Surveillance, Postmarketing / Q000379:methods*; D014612:Vaccines / Q000009:adverse effects* / Q000276:immunology*
D014612:Vaccines