A pilot study revealing impaired P50 gating in antisocial personality disorder.
The authors investigated preattentive filtering assessed by P50 gating in nine participants with antisocial personality disorder (ASPD) and seven with adult-onset antisocial behavior (AAB). Relative to 15 comparison subjects, gating was impaired in ASPD, suggesting abnormal pre-attentive filtering in pathological impulsivity.
Department of Psychiatry and Behavioral Sciences, University of Texas, Houston, USA. marijn.lijffijt@uth.tmc.edu
Marijn
M
Lijffijt
F Gerard
FG
Moeller
Nash N
NN
Boutros
S
S
Burroughs
Joel L
JL
Steinberg
Scott D
SD
Lane
Alan C
AC
Swann
D000161:Acoustic Stimulation; D000328:Adult; D017668:Age of Onset; D000704:Analysis of Variance; D000987:Antisocial Personality Disorder / Q000503:physiopathology*; D001307:Auditory Perception / Q000502:physiology; D001921:Brain / Q000503:physiopathology*; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010865:Pilot Projects; D013997:Time Factors