Acute monocytic leukemia in pregnancy. Report of a case treated with 6-mercaptopurine in the first trimester.
6-Mercaptopurine given during pregnancy to a patient suffering from acute monocytic leukemia (histiocytic or Schilling's type) permitted the birth of a premature but otherwise normal infant. The drug was given from the sixth to the eighth week and from the twenty-eighth to the thirty-first week of pregnancy, in doses sufficient to cause two remissions and two episodes of hypoplastic anemia.
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D005260:Female; D006801:Humans; D007223:Infant; D007948:Leukemia, Monocytic, Acute / Q000188:drug therapy*; D015122:Mercaptopurine / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D011261:Pregnancy Trimester, First
D015122:Mercaptopurine