Pregnancy and Crimean-Congo haemorrhagic fever.
Crimean-Congo Hemorrhagic fever (CCHF) is a potentially fatal viral infection with reported case fatality rates of 5-30%. Humans become infected through tick bites, by contact with a patient with CCHF during the acute phase of infection, or by contact with blood or tissues from viraemic livestock. In this first report in the literature, we present the characteristics of three pregnant women with CCHF infection and the outcome of their babies. Transmission of the CCHF infection could be either intrauterine or perinatal. In endemic regions, CCHF infection should be considered in the differential diagnosis of HELLP syndrome (haemolytic anaemia, elevated liver enzymes, low platelet count), and obstetricians should be familiar with the characteristics of CCHF infection. In the aetiology of necrotising enterocolitis, CCHF should be considered.
Ankara Numune Education and Research Hospital-Infectious Diseases, Ankara, Turkey. onderergonul@yahoo.com
O
O
Ergonul
A
A
Celikbas
U
U
Yildirim
A
A
Zenciroglu
D
D
Erdogan
I
I
Ziraman
F
F
Saracoglu
N
N
Demirel
O
O
Cakmak
B
B
Dokuzoguz
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000302:isolation & purification*; D006479:Hemorrhagic Fever, Crimean / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D018445:Infectious Disease Transmission, Vertical; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D012367:RNA, Viral / Q000235:genetics; D016896:Treatment Outcome
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012367:RNA, Viral