Infective endocarditis caused by Salmonella enteritidis in a dialysis patient: a case report and literature review.
BACKGROUND
Infective endocarditis is significantly more common in haemodialysis patients as compared with the general population, the causative pathogen is generally Staphylococcus aureus; there have been no previously reported cases of infective endocarditis caused by a Salmonella species in haemodialysis patients.


METHODS
We report the case of a 68 year-old woman on haemodialysis who developed infective endocarditis as a result of Salmonella enteritidis. Although we treated the patient with ceftriaxone combined with ciprofloxacin, infective endocarditis was not detected early enough and unfortunately developed into cerebral septic emboli, which ultimately resulted in death.


CONCLUSIONS
Although there are several reports that Salmonella endocarditis without cardiac failure can be successfully treated with antibiotics alone, early surgical intervention is essential for some cases to prevent life-threatening complications. Transesophageal echocardiography should be performed in any patient with high clinical suspicion of infective endocarditis. To the best of our knowledge, this is the first case-report of Salmonella endocarditis in a haemodialysis patient.
Department of Nephrology, Division of Internal Medicine, St. Luke's International Hospital, Tokyo, Japan. yusuke@luke.or.jp
Yusuke
Y
Tsugawa
Miyuki
M
Futatsuyama
Keiichi
K
Furukawa
Fumika
F
Taki
Yuji
Y
Nishizaki
Keiichi
K
Tamagaki
Yuki
Y
Kaneshiro
Yasuhiro
Y
Komatsu
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D006435:Renal Dialysis; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy; D012477:Salmonella enteritidis / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002443:Ceftriaxone