Immobilization of bis(bipyridine) BINOL ligands and their use in chiral resolution.
An enantiomerically pure bis(bipyridine) BINOL ligand was synthesized which was functionalized with an iodine substituent in its periphery. Using this halogen function, the ligand was immobilized on a commercially available polystyrene gel via Suzuki cross-coupling. The functionalized gel was found to be effective in the chiral resolution of similar bis(bipyridine) ligands based on a Tröger's base core.
Bunzen
Jens
J
Kekulé Institut für Organische Chemie und Biochemie, Rheinische Friedrich-Wilhelms-Universität Bonn, Gerhard-Domagk-Strasse 1, D-53121 Bonn, Germany.
Kiehne
Ulf
U
Benkhäuser-Schunk
Christian
C
Lützen
Arne
A