Beyond specific pathogen-free: biology and effect of common viruses in macaques.
Macaque models have contributed to key advances in our basic knowledge of behavior, anatomy, and physiology as well as to our understanding of a wide variety of human diseases. This issue of Comparative Medicine focuses on several of the viral agents (members of Retroviridae, Herpesviridae and 2 small DNA viruses) that can infect both nonhuman primates and humans as well as confound research studies. Featured articles also address the challenges of developing colonies of macaques and other nonhuman primates that are truly specific pathogen-free for these and other adventitious infectious agents.
California National Primate Research Center, University of California, Davis, CA, USA.
Nicholas W
NW
Lerche
Joe H
JH
Simmons
D000818:Animals; D004266:DNA Virus Infections / Q000235:genetics / Q000662:veterinary; D020022:Genetic Predisposition to Disease; D016679:Genome, Viral; D006566:Herpesviridae Infections / Q000235:genetics / Q000662:veterinary; D006801:Humans; D008251:Macaca / Q000235:genetics / Q000821:virology*; D012328:RNA Viruses / Q000235:genetics; D012106:Research / Q000639:trends; D012190:Retroviridae / Q000235:genetics; D012192:Retroviridae Infections / Q000235:genetics / Q000662:veterinary; D013047:Specific Pathogen-Free Organisms / Q000502:physiology*; D014777:Virus Diseases / Q000235:genetics / Q000662:veterinary*