Ceftazidime activity in experimental pseudomonas pyelonephritis in rats.
In albino rats with experimental unilateral pyelonephritis caused by a strain of Pseudomonas aeruginosa, the intramuscular administration of 25 mg/kg or 50 mg/kg of ceftazidime three times a day for 3 days reduced the bacterial counts in the damaged kidney, the undamaged kidney and in the bladder urine.
Ritzerfeld
W
W
Hygiene-Institut der Universität Münster, Westring 10, 4400 Münster/W, West Germany.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002442:Ceftazidime / Q000627:therapeutic use*; D015169:Colony Count, Microbial; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D011552:Pseudomonas Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D011704:Pyelonephritis / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D051381:Rats
D000900:Anti-Bacterial Agents; D002442:Ceftazidime