Structural changes of fovea during remission of Behçet's disease as imaged by spectral domain optical coherence tomography.
OBJECTIVE
To acquire the image of the fovea during remission of ocular Behçet's disease using spectral domain optical coherence tomography (SD-OCT) and to further assess the correlation between best-corrected visual acuity (BCVA) and SD-OCT findings.


METHODS
A total of 24 eyes of 14 patients with ocular Behçet's disease were examined with SD-OCT. The relationships between BCVA and other clinical characteristics, including foveal thickness and status of external limiting membrane (ELM) or the junction between photoreceptor inner and outer segments (IS/OS), were analysed for statistical significance.


RESULTS
BCVA in eyes with intact IS/OS was significantly better than that in eyes with ill-defined IS/OS (P=0.0001). Foveal thickness (P=0.0001) and male sex (P=0.03) were also significantly different between eyes with and without complete IS/OS line.


CONCLUSIONS
Definition of the IS/OS line by SD-OCT, but not status of the ELM line, appears to be associated with BCVA in patients with ocular Behçet's disease. Accordingly, SD-OCT may prove useful in the evaluation of visual function after ocular attacks of Behçet's disease.
Department of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
N
N
Unoki
K
K
Nishijima
M
M
Kita
R
R
Hayashi
N
N
Yoshimura
D000328:Adult; D000368:Aged; D001528:Behcet Syndrome / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult