Infarction in the territory of anterior inferior cerebellar artery: spectrum of audiovestibular loss.
OBJECTIVE
To define the detailed spectrum of audiovestibular dysfunction in anterior inferior cerebellar artery territory infarction.


METHODS
Over 8.5 years, we prospectively identified 82 consecutive patients with anterior inferior cerebellar artery territory infarction diagnosed by MRI. Each patient completed a standardized audiovestibular questionnaire and underwent a neuro-otologic evaluation, including bithermal caloric tests and pure tone audiogram.


RESULTS
All but 2 (80 of 82 [98%]) patients had acute prolonged vertigo and vestibular dysfunction of peripheral, central, or combined origin. The most common pattern of audiovestibular dysfunction was the combined loss of auditory and vestibular function (n=49 [60%]). A selective loss of vestibular (n=4 [5%]) or cochlear (n=3 [4%]) function was rarely observed. We could classify anterior inferior cerebellar artery territory infarction into 7 subgroups according to the patterns of neuro-otological presentations: (1) acute prolonged vertigo with audiovestibular loss (n=35); (2) acute prolonged vertigo with audiovestibular loss preceded by an episode(s) of transient vertigo/auditory disturbance within 1 month before the infarction (n=13); (3) acute prolonged vertigo and isolated auditory loss without vestibular loss (n=3); (4) acute prolonged vertigo and isolated vestibular loss without auditory loss (n=4); (5) acute prolonged vertigo but without documented audiovestibular loss (n=24); (6) acute prolonged vertigo and isolated audiovestibular loss without any other neurological symptoms/signs (n=1); and (7) nonvestibular symptoms with normal audiovestibular function (n=2).


CONCLUSIONS
Infarction in the anterior inferior cerebellar artery territory can present with a broad spectrum of audiovestibular dysfunctions. Unlike a viral cause, labyrinthine dysfunction of a vascular cause usually leads to combined loss of both auditory and vestibular functions.
Department of Neurology, Keimyung University School of Medicine, 194 Dongsan dong, Daegu, 700-712 South Korea. hlee@dsmc.or.kr
Hyung
H
Lee
Ji Soo
JS
Kim
Eun-Ji
EJ
Chung
Hyon-Ah
HA
Yi
In-Sung
IS
Chung
Seong-Ryong
SR
Lee
Je-Young
JY
Shin
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001299:Audiometry; D001488:Basilar Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D001933:Brain Stem / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D020526:Brain Stem Infarctions / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D002150:Caloric Tests; D002526:Cerebellar Diseases / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D002531:Cerebellum / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011859:Radiography; D011795:Surveys and Questionnaires; D014715:Vertebrobasilar Insufficiency / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D014717:Vertigo / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D015837:Vestibular Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D055815:Young Adult