Merkel cell polyomavirus DNA in persons without merkel cell carcinoma.
Merkel cell polyomavirus (MCPyV) DNA was detected in 88% of Merkel cell carcinomas in contrast to 16% of other skin tumors. MCPyV was also found in anogenital and oral samples (31%) and eyebrow hairs (50%) of HIV-positive men and in forehead swabs (62%) of healthy controls. MCPyV thus appears to be widespread.
Wieland
Ulrike
U
Institute of Virology, University of Cologne, Koeln, Germany. ulrike.wieland@uni-koeln.de
Mauch
Cornelia
C
Kreuter
Alexander
A
Krieg
Thomas
T
Pfister
Herbert
H
D015266:Carcinoma, Merkel Cell / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis / Q000302:isolation & purification*; D005138:Eyebrows / Q000821:virology*; D005546:Forehead / Q000821:virology; D005837:Genitalia, Male / Q000821:virology; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D009055:Mouth / Q000821:virology; D011120:Polyomavirus / Q000235:genetics / Q000302:isolation & purification*; D027601:Polyomavirus Infections / Q000821:virology*; D012867:Skin / Q000821:virology*; D014412:Tumor Virus Infections / Q000821:virology*
D004279:DNA, Viral