Update: prostate cancer early detection clinical practice guidelines.
Histopathologic analysis of a biopsy specimen of the prostate, examined to ascertain the presence of malignancy, can result in 4 possible diagnostic scenarios: (1) prostate cancer, (2) no evidence of cancer, (3) high-grade prostatic intraepithelial neoplasia, and (4) atypical small-gland proliferation suggestive of malignancy but not diagnostic. Until new studies provide a better method for selecting patients to undergo rebiopsy, patients diagnosed with high-grade prostatic intraepithelial neoplasia from a single core biopsy should undergo rebiopsy. A diagnosis of atypical glands suggestive of malignancy indicates that a rebiopsy should be performed because the chances of finding an invasive carcinoma are high.
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. aayala@mail.mdanderson.org
Alberto G
AG
Ayala
D055088:Early Detection of Cancer; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D011471:Prostatic Neoplasms / Q000175:diagnosis*