Straightforward synthesis of the near-infrared fluorescent voltage-sensitive dye RH1691 and analogues thereof.
A highly straightforward synthesis of the near-infrared voltage-sensitive dye RH1691 is reported featuring two sequential anionic additions of C-nucleophilic heterocycles on a cyanine. This convergent approach led to the synthesis of four new probes, which also exhibit fluorescence in the near-infrared region.
Lebeuf
Raphaël
R
Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Férézou
Isabelle
I
Rossier
Jean
J
Arseniyadis
Stellios
S
Cossy
Janine
J
D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis; D007259:Infrared Rays; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
D005456:Fluorescent Dyes; D011720:Pyrazoles; C471342:RH1691; D013844:Thiazoles