A cyclohexenone derivative from Diaporthaceous fungus PSU-H2.
One new cyclohexenone derivative (1) was isolated from Diaporthaceous fungus PSU-H2 together with six known compounds, dothiorelone A (2), dothiorelone C (3), 2,3-dihydromycoepoxydiene (4), (+)-mycoepoxydiene (5), deacetylmycoepoxydiene (6) and tyrosol (7). The structures were elucidated by spectroscopic methods. Their cytotoxic activity against human breast cancer cell line, MCF-7, was evaluated.
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand.
Ubonta
U
Sommart
Vatcharin
V
Rukachaisirikul
Yaowapa
Y
Sukpondma
Souwalak
S
Phongpaichit
Nongporn Hutadilok
NH
Towatana
Potchanapond
P
Graidist
Zuboidah
Z
Hajiwangoh
Jariya
J
Sakayaroj
D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005658:Fungi / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy
D000970:Antineoplastic Agents; D003512:Cyclohexanones