Solitary fibrous tumor.
Intracranial solitary fibrous tumors (SFT) are typically dural based, CD34-positive neoplasms of mesenchymal origin. Since they were first described in 1996 at the meninges, fewer than 100 SFT had been reported in both cranial and spinal compartments of the central nervous system. SFT can resemble other spindle cell tumors both radiologically and histopathologically, and differentiation can be best achieved through viewing their ultrastructure and using immunohistochemical techniques. In this report, we present four patients with SFT. Upon diagnosing two patients with SFT located in the cerebellopontine angle and parasagittal areas, we reviewed our pathological files and found two more patients; one having a parasagittal tumor and the other having a convexity tumor, that had been diagnosed with hemangiopericytoma. These tumours proved to be SFT after an immunohistochemical re-examination.
Department of Neurosurgery, Baskent University, Fevzi Cakmak Caddesi, 10. sokak No. 45 C Blok 1. kat 06490 Bahcelievler, Ankara, Turkey. cemy@baskent-ank.edu.tr
Cem
C
Yilmaz
Serdar
S
Kabatas
Ozlem Isiksacan
OI
Ozen
Salih
S
Gulsen
Hakan
H
Caner
Nur
N
Altinors
D000071443:12E7 Antigen; D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D018952:Antigens, CD34 / Q000378:metabolism; D015815:Cell Adhesion Molecules / Q000378:metabolism; D002531:Cerebellum / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D011149:Pons / Q000473:pathology; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D012189:Retrospective Studies; D054364:Solitary Fibrous Tumors / Q000378:metabolism / Q000473:pathology; D014746:Vimentin / Q000378:metabolism
D000071443:12E7 Antigen; D015703:Antigens, CD; D018952:Antigens, CD34; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D019253:Proto-Oncogene Proteins c-bcl-2; D014746:Vimentin