Chemical and structural biology to direct the repurposing of sulindac.
Simard
Jeffrey R
JR
Chemical Genomics Centre of the Max-Planck-Society, Dortmund, Germany.
Rauh
Daniel
D
D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry* / Q000378:metabolism; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry*; D001665:Binding Sites; D003198:Computer Simulation; D016861:Cyclooxygenase Inhibitors / Q000737:chemistry; D000072261:Dishevelled Proteins; D010750:Phosphoproteins / Q000737:chemistry* / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D017434:Protein Structure, Tertiary; D015398:Signal Transduction; D013467:Sulindac / Q000737:chemistry*; D051153:Wnt Proteins / Q000378:metabolism
D048868:Adaptor Proteins, Signal Transducing; D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D000072261:Dishevelled Proteins; D010750:Phosphoproteins; D051153:Wnt Proteins; D013467:Sulindac; D011451:Prostaglandin-Endoperoxide Synthases