[Aetiology of epileptic seizures in a rehabilitation centre].
BACKGROUND
Epileptic seizures are a common complication among patients who are admitted to rehabilitation hospitals. This work examines aspects related to their aetiology and progress.


METHODS
The study involved all the patients with a history of epileptic seizures who had been consecutively admitted for rehabilitation during the second semester of 2008. The protocol for data collection included sociodemographic variables, the aetiology, type, frequency and complications of the seizures, and their treatment and side effects.


RESULTS
An analysis was performed on 160 patients (62.5% males; mean age: 43.6 years). The main aetiologies were the following: stroke (41.2%), traumatic brain injury (35%), meningitis/encephalitis (5%), primary brain tumour (3.8%), anoxia (3.8%), static encephalopathy (3.8%) and others (7.6%). 7.6% had a history of epilepsy before suffering the brain injury. 16.3% had had a single epileptic seizure. 6.2% presented treatment failure with two antiepileptic drugs, and 12.5% suffered from more than one seizure per month. 17.5% of the patients had suffered from an epileptic status. In semiological terms, the most common seizures were focal seizures (54.5%), generalised seizures (44.4%) and focal seizures with secondary generalisation (31.9%). 76% of the subjects took antiepileptic drugs on a regular basis, but the caregiver was responsible for medication in 70% of cases. Carbamazepine and valproate were the two most frequently used drugs.


CONCLUSIONS
Epilepsy can limit rehabilitation therapy in patients with stroke or traumatic injury, due to the risk of developing difficult-to-treat epilepsy. Caregivers often have to take responsibility for the pharmacological treatment in disabled patients with brain damage.
Servicio de Neurología, Hospital Sarah, Red Sarah de Hospitales de Rehabilitación, Brasilia DF, Brasil. fjcarod-artal@hotmail.com
F J
FJ
Carod-Artal
A P
AP
Vargas
H M
HM
Mesquita
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000927:Anticonvulsants / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications / Q000534:rehabilitation; D002220:Carbamazepine / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012047:Rehabilitation Centers; D014635:Valproic Acid / Q000627:therapeutic use; D055815:Young Adult
D000927:Anticonvulsants; D002220:Carbamazepine; D014635:Valproic Acid