Different phenotypes of polycystic ovary syndrome by Rotterdam criteria are differently steroidogenic but similarly insulin resistant.
In traditional Chinese medicine, polycystic ovary syndrome (PCOS) is considered an anovulation disorder related to ovarian insulin resistance. The three phenotypes of PCOS, according to the Rotterdam criteria, are differently steroidogenic but similarly insulin resistant, suggesting a similar involvement of insulin resistance/hyperinsulinemia in different compartments of the PCOS ovary, namely, overactive theca and/or granulosa cells.
Medical School, Nanjing University, Nanjing, People's Republic of China.
Yong
Y
Wang
JunWei
J
Qu
XiaoKe
X
Wu
Lihui
L
Hou
Risto
R
Erkkola
Yongyan
Y
Wang
D000328:Adult; D003955:Diagnostic Tests, Routine / Q000592:standards; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000235:genetics*; D010053:Ovary / Q000473:pathology; D010641:Phenotype; D010865:Pilot Projects; D011085:Polycystic Ovary Syndrome / Q000145:classification / Q000175:diagnosis* / Q000235:genetics*