Four new lignans from Viburnum foetidum var. foedidum.
The 70% aqueous acetone extract of the aerial part of Viburnum foetidum var. foedidum afforded four new lignans (1-4) together with six known ones. The structures of the four new compounds were elucidated on the basis of 1D (dimensional), 2D-NMR, and mass spectral analysis. The structure of compound 1, with a novel spirocyclic moiety, was also confirmed by X-ray diffraction analysis. Compounds 1-10 were evaluated for their cytotoxic activity. However, none of the compounds showed significant cytotoxic activity.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650204, PR China.
Xuan-Qin
XQ
Chen
Yan
Y
Li
Juan
J
He
Kou
K
Wang
Ming-Ming
MM
Li
Zheng-Hong
ZH
Pan
Li-Yan
LY
Peng
Xiao
X
Cheng
Qin-Shi
QS
Zhao
D018360:Crystallography, X-Ray; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D027925:Viburnum / Q000737:chemistry*
D017705:Lignans; D010936:Plant Extracts