Cord blood transplantation for haematological malignancies: conditioning regimens, double cord transplant and infectious complications.
Growing evidence supports the efficacy of cord blood transplantation (CBT) to treat patients with haematological malignancies, and the number of CBTs is rapidly increasing. Herein, we review considerations regarding conditioning regimens for CBT, the impact of double unit transplantation on CBT outcomes, and data regarding infectious complications following CBT.
Delaney
Colleen
C
Fred Hutchinson Cancer Research Center, University of Washington, D2-100, 1100 Fairview Ave North, Seattle, WA 98109, USA. sdelaney@fhcrc.org
Gutman
Jonathan A
JA
Appelbaum
Frederick R
FR
D000465:Algorithms; D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods*; D046148:Donor Selection / Q000379:methods; D019337:Hematologic Neoplasms / Q000628:therapy*; D006801:Humans; D009894:Opportunistic Infections / Q000209:etiology*; D019172:Transplantation Conditioning / Q000379:methods*; D014916:Whole-Body Irradiation / Q000379:methods