Urinary uric acid in preterm neonates.
OBJECTIVE
Study of uric acid level in spot urine of normal preterm AGA (appropriate for gestational age) babies in day one of their life.


METHODS
Spot urine samples were collected from 45 normal preterm neonates within 24 hours of their birth for estimation of uric acid.


RESULTS
The mean uric acid level was 36.50 +/- 5.99 mg/dl in normal preterm neonates as compared to 18.40 +/- 0.45 mg/dl in normal term babies (documented in another study) (p < 0.001). Also a significant negative linear correlation between body weight and urinary uric acid level was found {r (correlation coefficient) = - 0.970, P (probability) < 0.001 }.


CONCLUSIONS
Higher mean uric acid level was found in spot urine samples of preterm normal neonates than that of normal term babies on day one. Further, urinary uric acid levels were found inversely proportional to the body weight or to the gestational age (as they are AGA) of the babies.
Department of Biochemistry, Burdwan Medical College and Hospital, Burdwan, West Bengal, India. basu_pallab@yahoo.co.in
Pallab
P
Basu
Sabyasachi
S
Som
Nabendu
N
Choudhuri
Harendranath
H
Das
D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000652:urine*; D016014:Linear Models; D008297:Male; D014527:Uric Acid / Q000652:urine*
D014527:Uric Acid