Pearling of lipid vesicles induced by nanoparticles.
We show that cationic nanoparticles encapsulated within vesicles of phosphocholine lipid can induce pearling. The dynamic process occurs as two stages: formation of tubular protrusions followed by pearling instability. The breakup into individual vesicles can be controlled by nanoparticle concentration.
Department of Material Science and Enginering, University of Illinois, Urbana, Illinois 61801, USA.
Yan
Y
Yu
Steve
S
Granick
D008081:Liposomes / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry; D010714:Phosphatidylethanolamines / Q000737:chemistry; D010767:Phosphorylcholine / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry
D008081:Liposomes; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D012235:Rhodamines; C046703:lissamine-rhodamine-phosphatidylethanolamine; D010767:Phosphorylcholine; C020888:1,2-dielaidoylphosphatidylethanolamine; C017251:1,2-oleoylphosphatidylcholine