Esthetic outcome of surgical excision versus antibiotic therapy for nontuberculous mycobacterial cervicofacial lymphadenitis in children.
One hundred children with microbiologically proven nontuberculous mycobacterial cervicofacial lymphadenitis were randomly assigned to excision of the involved lymph nodes, or antibiotic therapy consisting of clarithromycin and rifabutin. The esthetic outcome was rated using a revised and weighted Observer Scar Assessment Scale. The median weighted esthetic outcome in surgical patients was significantly better (30.6) than that for patients treated with antibiotics (42.2).
Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam, The Netherlands. j.a.lindeboom@amc.uva.nl
Jerome A
JA
Lindeboom
Robert
R
Lindeboom
Elisabeth S
ES
Bruijnesteijn van Coppenraet
Ed J
EJ
Kuijper
Jacco
J
Tuk
Jan M
JM
Prins
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017291:Clarithromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008197:Lymph Node Excision; D008199:Lymphadenitis / Q000188:drug therapy* / Q000601:surgery*; D008297:Male; D009164:Mycobacterium Infections / Q000188:drug therapy* / Q000601:surgery*; D017828:Rifabutin / Q000627:therapeutic use; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D017828:Rifabutin; D017291:Clarithromycin