Pancreatitis and systemic lupus erythematosus.
Gastrointestinal symptoms in patients with SLE are common, specifically abdominal pain. However, the rate of pancreatic diseases is much lower and does not reach 5% according to published series in Europe and the USA. This association between SLE and pancreatic disease is basically at the expense of episodes of acute pancreatitis. An association with chronic pancreatitis is much more uncommon, and only four articles have been published showing this relationship. Three cases of SLE-associated pancreatitis are described, and disease onset, etiological factors, and clinical progression are analyzed. A review of the literature and a brief discussion about pathophysiological mechanisms and the role of corticosteroids are also included.
Gastroenterology Department, University Hospital of Santiago, Santiago de Compostela, A Coruña, Spain. jlarnoi1976@fienad.com
J
J
Lariño Noia
F
F
Macías García
S
S
Seijo Ríos
J
J
Iglesias García
J E
JE
Domínguez Muñoz
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D049448:Cholangiopancreatography, Magnetic Resonance; D018450:Disease Progression; D019160:Endosonography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D010179:Pancreas / Q000503:physiopathology; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D050500:Pancreatitis, Chronic / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones