[Methotrexate: mainstay of rheumatoid arthritis treatment].
Some accidents due to methotrexate (MTX) have been reported to the Dutch Health Authorities. However, for modern, intensive treatment of patients with rheumatoid arthritis and various other chronic autoimmune diseases, we cannot do without the drug, because of its broad applications and unique properties. Fortunately, it is a safe drug, if used by doctors experienced in using it and who follow MTX guidelines.
Jacobs
J W G Hans
JW
Universitair Medisch Centrum Utrecht, afd. Reumatologie en Klinische Immunologie, Utrecht, The Netherlands. j.w.g.jacobs@umcutrecht.nl
Bijlsma
J W J Hans
JW
D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004334:Drug Administration Schedule; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
D018501:Antirheumatic Agents; D008727:Methotrexate