Outbreak caused by cad-negative Shiga toxin-producing Escherichia coli O111, Oklahoma.
An outbreak of severe diarrheal illness was recently reported in northeastern Oklahoma, and Shiga toxin-producing Escherichia coli serotype O111 was identified as the etiological agent. Our results indicated that this isolate is unable to decarboxylate lysine, a characteristic that is shared with other outbreak-linked O111 isolates. Therefore, further investigation is recommended to determine whether the lysine decarboxylase test could be used to identify a subset of pathogenic E. coli, particularly Shiga toxin-producing E. coli O111 isolates, that have the potential of causing human infections and outbreaks.
Calderon
Veronica E
VE
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas 77555-1070, USA.
Chang
Qing
Q
McDermott
Mike
M
Lytle
Michael B
MB
McKee
Garry
G
Rodriguez
Krystle
K
Rasko
David A
DA
Sperandio
Vanessa
V
Torres
Alfredo G
AG
D002262:Carboxy-Lyases / Q000235:genetics* / Q000378:metabolism; D004196:Disease Outbreaks; D004403:Dysentery / Q000453:epidemiology / Q000382:microbiology; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics; D005517:Foodborne Diseases / Q000453:epidemiology / Q000382:microbiology; D005798:Genes, Bacterial; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008239:Lysine / Q000378:metabolism*; D009825:Oklahoma / Q000453:epidemiology; D009876:Operon; D010641:Phenotype; D016133:Polymerase Chain Reaction; D054323:Shiga-Toxigenic Escherichia coli / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D013045:Species Specificity; D014774:Virulence / Q000235:genetics
D029968:Escherichia coli Proteins; D002262:Carboxy-Lyases; C021520:lysine decarboxylase; D008239:Lysine