[Molecular dynamics of zervamicin II and its analogues in water and methanol].
A comparative study of the molecular dynamics of zervamicin II (an antimicrobial peptide from the peptaibol group, which has the channel-forming activity) in water and methanol has been performed. The influence of amino acid substitutions on the dynamics and stability of the peptide structure has been investigated. The amino acid sequence responsible for the absence of swivel motions in short peptaibols has been determined.
Levtsova
O V
OV
Antonov
M Iu
MIu
Shaĭtan
A K
AK
Orshanskiĭ
I A
IA
Nikolaev
I N
IN
Shaĭtan
K V
KV
D000432:Methanol / Q000737:chemistry*; D054848:Peptaibols / Q000737:chemistry*; D017433:Protein Structure, Secondary; D013816:Thermodynamics; D014867:Water / Q000737:chemistry*
D054848:Peptaibols; D014867:Water; D000432:Methanol