[Diffuse systemic sclerosis after occupational exposure to trichloroethylene and perchloroethylene].
BACKGROUND
Diffuse systemic sclerosis (DSS) is an autoimmune disease that is most often endogenous but which can also be induced by exogenous substances of occupational origin.


METHODS
We report a case of DSS involving prolonged intermittent occupational exposure to solvents (trichloroethylene [TCE] and perchloroethylene [PCE]). The disease was rapidly fatal with cardiac arrest secondary to myocardial fibrosis.


CONCLUSIONS
In the event of exposure to TCE/PCE, we suggest more systematic prevention and diagnosis of DSS.
Service de dermatologie, centre hospitalier de Valence, 59, boulevard Pinel, 69500 Bron, France.
P
P
Pralong
A
A
Cavailhes
B
B
Balme
V
V
Cottin
F
F
Skowron
D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D045743:Scleroderma, Diffuse / Q000139:chemically induced*; D013750:Tetrachloroethylene / Q000009:adverse effects*; D014241:Trichloroethylene / Q000009:adverse effects*
D014241:Trichloroethylene; D013750:Tetrachloroethylene