Epithelioid angiomyolipoma associated with a classic angiomyolipoma.
We report a case of renal epithelioid angiomyolipoma that arose in association with a classic angiomyolipoma in a 54-year-old Japanese man without tuberous sclerosis. Histologically, the tumor was composed of polygonal cells exhibiting diffuse hemorrhage, multifocal necroses, and vascular invasion. Immunohistochemical staining was positive for melanoma specific antibody and focally positive for smooth muscle actin. On the basis of a review of the literature, we suggest that large epithelioid angiomyolipoma may have malignant potential and therefore requires close follow up.
Department of Urology, Toyota Memorial Hospital, Toyota, Japan.
Seiichi
S
Kato
Kensaku
K
Seike
Takako
T
Masue
Naoki
N
Yamamoto
Shinichi
S
Maeda
D018207:Angiomyolipoma / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D015622:Epithelioid Cells / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed