Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor.
OBJECTIVE
Ectomesenchymal chondromyxoid tumor is a rare oral soft tissue neoplasm that should be differentiated from other neural and chondromyxoid entities. The aim of this study was to report the clinical, histological, and immunohistochemical features of 3 additional cases of this condition.


METHODS
Clinical data were obtained from the clinical records and all cases were evaluated through light microscopy and immunohistochemistry to cytokeratins, vimentin, S100 protein, desmin, smooth muscle actin, and glial fibrilary acidic protein.


RESULTS
All 3 cases affected the tongue as a long-lasting submucosal swelling and were managed through conservative surgery. They all showed myxoid and chondroid histological patterns, and vimentin, S100, and glial fibrilary acidic protein immunoexpression.


CONCLUSIONS
These findings reinforce the typical features of ectomesenchymal chondromyxoid tumor previously described, helping to confirm and establish the clinical, histopathological, and immunohistochemical profile of this uncommon lesion.
Pires
Fábio Ramôa
FR
School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, Brazil. ramoafop@yahoo.com
Abrahão
Aline Correa
AC
Cabral
Márcia Grillo
MG
Azevedo
Rebeca Souza
RS
Horta
Martinho Campolina Rebello
MC
Martins
Carlos Roberto
CR
de Almeida
Oslei Paes
OP
Chen
Sow-Yeh
SY
D000293:Adolescent; D000328:Adult; D000951:Antigens, Neoplasm / Q000276:immunology*; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008637:Mesenchymoma / Q000276:immunology / Q000473:pathology*; D008648:Mesoderm / Q000473:pathology; D009208:Myoepithelioma / Q000276:immunology / Q000473:pathology; D009232:Myxoma / Q000276:immunology / Q000473:pathology*; D009373:Neoplasms, Germ Cell and Embryonal / Q000276:immunology / Q000473:pathology*; D014062:Tongue Neoplasms / Q000276:immunology / Q000473:pathology*
D000951:Antigens, Neoplasm