Fulminant necrotizing fasciitis due to Vibrio parahaemolyticus.
Necrotizing soft-tissue infection due to Vibrio parahaemolyticus is unusual. We report a case of necrotizing fasciitis due to V. parahaemolyticus in a 92-year-old woman with a history of chronic renal failure, diabetes mellitus and malnutrition. Clinical evolution was fulminant and the patient died 6 h after admission. A review of all cases previously reported showed that the infection occurred in patients with underlying diseases through ingestion of raw oysters or inoculation via traumatic injury in marine environments. The mortality rate of all reviewed cases was 42.8 %. In conclusion, V. parahaemolyticus should be considered a possible causative agent of necrotizing fasciitis, especially in patients with underlying disease. Early diagnosis and prompt aggressive debridement associated with antibiotic therapy are essential in order to save the patient's life, because clinical evolution can be fulminant and mortality rates are high.
Section of Microbiology, University Hospital of Guadalajara, Guadalajara, Spain.
Daniel
D
Tena
Section of Microbiology, University Hospital of Guadalajara, Guadalajara, Spain.
Marta
M
Arias
Service of Geriatrics, University Hospital of Guadalajara, Guadalajara, Spain.
Bárbara Teresa
BT
Álvarez
Service of Geriatrics, University Hospital of Guadalajara, Guadalajara, Spain.
Coro
C
Mauleón
Service of Geriatrics, University Hospital of Guadalajara, Guadalajara, Spain.
Mari Paz
MP
Jiménez
Section of Microbiology, University Hospital of Guadalajara, Guadalajara, Spain.
Julia
J
Bisquert
D000369:Aged, 80 and over; D019115:Fasciitis, Necrotizing / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D014735:Vibrio Infections / Q000382:microbiology*; D014736:Vibrio parahaemolyticus / Q000302:isolation & purification*