Low or undetectable numbers of Philadelphia chromosome-positive leukemic stem cells (Ph(+)CD34(+)CD38(neg)) in chronic myeloid leukemia patients in complete cytogenetic remission after tyrosine kinase inhibitor therapy.
Mustjoki
S
S
Rohon
P
P
Rapakko
K
K
Jalkanen
S
S
Koskenvesa
P
P
Lundán
T
T
Porkka
K
K
D051997:ADP-ribosyl Cyclase 1 / Q000032:analysis*; D000328:Adult; D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis*; D001549:Benzamides; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008562:Membrane Glycoproteins / Q000032:analysis*; D008875:Middle Aged; D014411:Neoplastic Stem Cells / Q000187:drug effects*; D010677:Philadelphia Chromosome; D010879:Piperazines / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use
D018952:Antigens, CD34; D001549:Benzamides; D008562:Membrane Glycoproteins; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate; C498154:CD38 protein, human; D051997:ADP-ribosyl Cyclase 1