[Impact of micronutrients on immunocyte and microelements status among people living with HIV].
OBJECTIVE
To explore the impact of micronutrients supplement on immunocyte and microelements status in HIV positive people.


METHODS
Volunteers aged 25-49 years old were randomly selected and distributed into two groups. Supplement and placebo were given to the two groups. At the beginning of the trial, data on physical examination, immunocyte and microelements level in serum of the two groups were collected and showed no significant difference (P > 0.05).


RESULTS
After 6 months, the amount of immunocyte (CD4+, CD8+, CD3+) were (2078 +/- 108) mm3, (582 +/- 75) mm3, (1287 +/- 97) mm3 in the study group while they were (1436 +/- 105) mm3, (472 +/- 61) mm3, (998 +/- 84) mm3 in the control group, with statistically significant difference (P < 0.05). Amounts of serum Zn, Ca, Mg, Fe showed (144.89 +/- 9.78) micromol/L, (1.89 +/- 0.19) micromol/L, (1.68 +/- 0.12) micromol/L, (152.61 +/- 8.94) micromol/L in the study group and they were (102.67 +/- 5.45) micromol/L, (1.13 +/- 0.07) micromol/L, (0.85 +/- 0.05) micromol/L, (89.24 +/- 3.91) micromol/L in the control group, with statistically significant difference (P < 0.05).


CONCLUSIONS
Supplementation of micronutrients could increase the levels of Zn, Ca, Mg, Fe so as to increase the immune function in people living with HIV.
School of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Fei
F
Zhao
Zhe
Z
Wang
Wen-jie
WJ
Li
D000163:Acquired Immunodeficiency Syndrome / Q000178:diet therapy* / Q000276:immunology* / Q000503:physiopathology; D000328:Adult; D015496:CD4-Positive T-Lymphocytes; D018414:CD8-Positive T-Lymphocytes; D002118:Calcium / Q000097:blood; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood; D008274:Magnesium / Q000097:blood; D008297:Male; D018977:Micronutrients / Q000627:therapeutic use*; D008875:Middle Aged; D015032:Zinc / Q000097:blood
D018977:Micronutrients; D007501:Iron; D008274:Magnesium; D015032:Zinc; D002118:Calcium