Multifocal diffuse oral melanoacanthoma: a case report.
Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains uncertain, its clinical behavior and spontaneous remission suggest a non-neoplastic nature. Clinically, it may present as a solitary or multifocal lesion; however these two variants exhibit different features. The clinical appearance of OMA is not pathognomonic and biopsy is mandatory. OMA requires no treatment or periodic observation. Here, we report a case of OMA with diffuse lesions also affecting the tongue in a 74-year-old black woman, whose diagnosis was based essentially on clinical and histological features. The immunohistochemical profile is also presented.
Marocchio
Luciana S
LS
Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil. lumarocchio@usp.br
Júnior
Décio S P
DS
de Sousa
Suzana C O M
SC
Fabre
Rebeca F
RF
Raitz
Ricardo
R
D049309:Acanthoma / Q000473:pathology*; D000368:Aged; D005260:Female; D006801:Humans; D008544:Melanocytes / Q000473:pathology; D008548:Melanosis / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*; D009365:Neoplasm Regression, Spontaneous