Laparoscopic cholecystectomy in patients with cirrhosis of the liver and symptomatic cholelithiasis.
BACKGROUND
The indications and benefits of laparoscopic cholecystectomy (LC) in patients with liver cirrhosis and symptomatic cholelithiasis have not been satisfactorily documented. The aim of this study was to investigate its efficacy and safety in such patients.


METHODS
Medical records of 38 patients with liver cirrhosis (stages Child-Pugh A and B) who underwent LC were retrospectively reviewed. Demographic characteristics and other parameters including initial presentation, conversion rate, complication rate, mortality, and duration of hospital stay were investigated and compared with noncirrhotic patients' parameters in our database.


RESULTS
Cirrhotic patients who underwent LC were older than noncirrhotic patients (P=0.021). Both the conversion rate (15.78%) and the duration of hospital stay were increased in the cirrhotic group, but without significant differences. Major complications occurred more often in the cirrhotic group (P=0.027), increasing morbidity; however, the mortality was zero.


CONCLUSIONS
LC can be safely performed in Child-Pugh A and B cirrhotic patients with symptomatic gallstone disease, with acceptable complication and conversion rates. The increased risk for a major complication, however, demands more attention than usual.
Pavlidis
Theodoros E
TE
Second Propedeutical Department of Surgery, Aristotle University of Thessaloniki, Hippocration Hospital, Greece. pavlidth@med.auth.gr
Symeonidis
Nikolaos G
NG
Psarras
Kyriakos
K
Skouras
Christos
C
Kontoulis
Theodoros M
TM
Ballas
Konstantinos
K
Rafailidis
Savas F
SF
Marakis
Georgios N
GN
Sakantamis
Athanasios K
AK
D016009:Chi-Square Distribution; D017081:Cholecystectomy, Laparoscopic; D002769:Cholelithiasis / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome