Ulcerated dermatofibroma with osteoclast-like giant cells.
BACKGROUND
Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion.


METHODS
We report the clinical, histopathological and immunohistochemical findings of a 38-year-old man with an ulcerated dermatofibroma (DF) on the sole containing OLGC.


CONCLUSIONS
DF, or cutaneous fibrous histiocytoma, is a frequent dermatological lesion with many clinicopathological variants. Therefore, a correct diagnosis is not always straightforward, especially when two rare features co-exist in the same lesion. Differential diagnosis was performed with cutaneous and even non-cutaneous lesions. An explanation for the clinicopathological findings is also described.
González-Vilas
Daniel
D
Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, Santiago de Compostela, Spain. jaime.toribio@usc.es
García-Gavín
Juan
J
Ginarte
Manuel
M
Rodríguez-Blanco
Isabel
I
Toribio
Jaime
J
D000328:Adult; D003937:Diagnosis, Differential; D005534:Foot Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D016523:Foot Ulcer / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D015726:Giant Cells / Q000378:metabolism / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery