Breast cancer in the Thai Cohort Study: an exploratory case-control analysis.
Breast cancer incidence may be increasing in Thailand but very little research has assessed core breast cancer risk factors in this country. We used baseline questionnaire data from a national cohort study of Thai Open University students in an exploratory case-control study of breast cancer. The study included 43 female cases and 860 age-matched controls selected from the remaining 47,271 female cohort participants. Odds ratios and 95% confidence intervals were calculated using conditional logistic regression. The women were predominantly premenopausal. Taller women had an increased risk of breast cancer (OR=2.3, 95% CI 1.1-4.8, for height >or=160cm vs <or=154cm) as did women with non-insulin dependent diabetes mellitus (OR=8.4, 95% CI 1.7-41). Women with older siblings had a reduced risk of breast cancer compared to those firstborn (OR=0.3, 95% CI 0.2-0.7). Although limited by small case numbers, our findings suggest substantial increases in breast cancer rates in Thailand could be expected in the future.
Jordan
Susan
S
School of Population Health, University of Queensland, Herston QLD, Brisbane, Australia. s.jordan@uq.edu.au
Lim
Lynette
L
Vilainerun
Duangkae
D
Banks
Emily
E
Sripaiboonkij
Nintita
N
Seubsman
Sam-ang
SA
Sleigh
Adrian
A
Bain
Christopher
C
D001722:Birth Order; D001827:Body Height; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000453:epidemiology*; D016022:Case-Control Studies; D015331:Cohort Studies; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D004032:Diet; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D010298:Parity; D011247:Pregnancy; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology