Fine needle aspiration of pleomorphic lipoma of the neck: report of two cases.
Pleomorphic lipoma is a rare lipocytic neoplasm that most commonly occurs in the head and neck region in middle-aged to elderly men. Clinically, it presents as a slow-growing, well-circumscribed subcutaneous mass. Histopathologically and cytogenetically, it has some features overlapping with other benign and malignant tumors, such as benign spindle cell lipoma, atypical lipomatous tumor, liposarcoma, and malignant fibrous histiocytoma. However, cure rates are high when pleomorphic lipoma is treated with complete surgical excision with clear margins. Therefore, an accurate preoperative diagnosis is very important for proper treatment. Due to the rarity of this tumor, few cases diagnosed by cytology have been reported in the English literature. Here, we report two cases of pleomorphic lipoma, the diagnoses of which were suggested on fine needle aspiration biopsies and subsequently confirmed by surgical excisions.
Department of Pathology, Division of Cytopathology, Columbia University Medical Center, New York, New York 10032, USA. xc2159@columbia.edu
Xiaowei
X
Chen
Kathy
K
Yu
Guo-Xia
GX
Tong
Melanie
M
Hood
Ian
I
Storper
Diane
D
Hamele-Bena
D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000378:metabolism; D044963:Biopsy, Fine-Needle; D002869:Chromosome Aberrations; D002902:Chromosomes, Human, 16-18; D002882:Chromosomes, Human, Pair 13; D003937:Diagnosis, Differential; D005218:Fat Necrosis / Q000175:diagnosis; D006258:Head and Neck Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008067:Lipoma / Q000235:genetics / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000473:pathology; D016896:Treatment Outcome
D014408:Biomarkers, Tumor