[Correlations between heart rate variability, renin activity and plasma aldosteron concentration in chronic glomerulonephritis with intact function of the kidneys].
OBJECTIVE
To study correlations between heart rate variability (HRV), renin activity and blood aldosteron in chronic glomerulonephritis (CGN) with intact renal function.


METHODS
A total of 136 CGN patients with intact renal function were examined (100 hypertensive and 36 normotensive patients). HRV was studied with 24-h ECG monitoring. Active renin (AR) and aldosteron in blood plasma was studied with radioimmunoassay.


RESULTS
The analysis of HRV detected a progressive attenuation of vegetative impacts on the cardiovascular system with aggravation of hypertension in CGN patients with intact renal function. In hypertension of the second and third degree AR and aldosteron levels increased.


CONCLUSIONS
With arterial hypertension progression in CGN patients with intact renal function, vegetative impacts on the cardiovascular system diminished while the levels of active renin and aldosterone rose.
N Iu
NIu
Borovkova
N N
NN
Borovkov
B N
BN
Sidnev
E O
EO
Obukhova
D000328:Adult; D000450:Aldosterone / Q000097:blood*; D001341:Autonomic Nervous System / Q000502:physiology; D002319:Cardiovascular System / Q000294:innervation; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000097:blood / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D007668:Kidney / Q000294:innervation / Q000502:physiology; D007677:Kidney Function Tests; D012083:Renin / Q000097:blood*; D012084:Renin-Angiotensin System / Q000502:physiology; D012720:Severity of Illness Index
D000450:Aldosterone; D012083:Renin