Colorimetric detection of thiols using a chromene molecule.
A new thiol-containing colorimetric probe has been developed by using a chromene derivative, 7-nitro-2,3-dihydro-1H-cyclopenta[b]chromen-1-one (1). The molecule exhibited high selectivity and sensitivity for detecting thiol species as cysteine, homocysteine, and glutathione in aqueous solution through a rapid visual color change from colorless to yellow.
Huo
Fang-Jun
FJ
Research Institute of Applied Chemistry, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, 030006, China.
Sun
Yuan-Qiang
YQ
Su
Jing
J
Chao
Jian-Bin
JB
Zhi
Hai-Juan
HJ
Yin
Cai-Xia
CX
D001578:Benzopyrans / Q000138:chemical synthesis / Q000737:chemistry*; D003124:Colorimetry / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000032:analysis*
C545766:7-nitro-2,3-dihydro-1H-cyclopenta(b)chromen-1-one; D001578:Benzopyrans; D005456:Fluorescent Dyes; D013438:Sulfhydryl Compounds