New caloporoside derivatives and their inhibition of fungal spore germination.
In our ongoing screening culture fluid extracts of Gloeoporus (Caloporus) dichrous strain 83065 inhibited the germination of Magnaporthe grisea and Fusarium graminearum spores. While isolating the active metabolites two new caloporosides, caloporoside G and caloporoside H, in addition to the known caloporoside derivatives F-16438G, caloporoside A, and 2-hydroxy-6-(16-hydroxyheptadecyl)benzoic acid were obtained.
University of Kaiserslautern, Paul-Ehrlich-Str. 23, D-67663 Kaiserslautern, Germany.
Anja
A
Schüffler
Johannes C
JC
Liermann
Heinz
H
Kolshorn
Till
T
Opatz
Timm
T
Anke
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D019169:Jurkat Cells / Q000187:drug effects; D007939:Leukemia L1210 / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D008358:Mannose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D051379:Mice; D012459:Salicylates / Q000737:chemistry / Q000494:pharmacology*; D013172:Spores, Fungal / Q000187:drug effects / Q000502:physiology*; D010738:Type C Phospholipases / Q000037:antagonists & inhibitors
D000935:Antifungal Agents; D012459:Salicylates; C091111:caloporoside; D010738:Type C Phospholipases; D008358:Mannose