Clinical observation on treatment of 32 patients with measles by qingzhen decoction.
OBJECTIVE
To observe the clinical effect of Qingzhen Decoction (QZD) on measles.


METHODS
Adopting the randomizing digital table, 62 patients with measles were assigned to two groups, 32 in the treated group and 30 in the control group. All patients were treated with routine therapy, but QZD was given to the treated group additionally for 5 days. Changes of clinical symptoms, blood routine and liver function before and after treatment were observed, and the medical cost was calculated.


RESULTS
After the 5-day treatment, the normalization rate of irritative cough in the treated and the control group was 88.9% (24/27) and 56.0% (14/25) respectively, that of conjunctival congestion was 90.0% (27/30) and 65.5% (19/29) respectively, showing significant differences between groups (P<0.05). The liver function normalization rate in the two groups was 28.6% (2/7) and 25.0% (2/8), and the average medical cost yen 740.7 and yen 749.3, respectively. The total effective rate in the two groups was 96.9% and 93.3% respectively, showing insignificant difference between groups (P>0.05).


CONCLUSIONS
QZD could actively improve the respiratory symptoms like irritative cough and the inflammatory symptoms of eye like conjunctival congestion in patients with measles.
Shanghai Pudong Infectious Disease Hospital, Shanghai, China.
Sheng-jie
SJ
Zhang
Chun-fang
CF
Wang
Yan-yan
YY
Qi
Jian-jie
JJ
Chen
D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008111:Liver Function Tests; D008297:Male; D008457:Measles / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D016896:Treatment Outcome
D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; C546212:qingzhen