Predicted environmental concentrations of cocaine and benzoylecgonine in a model environmental system.
A Mackay-type level II fugacity model has been used to predict the behaviour and final concentrations of cocaine (COC) and its main metabolite benzoylecgonine (BE) in a regional environmental system defined according to the European guidelines on Risk Assessment. The model takes into account the initial COC intake, partial degradation of the parent compound to BE, treatment of wastewater and environmental fate of these substances. Predicted environmental concentrations (PECs) lie in the ngL(-1) level, with the exception of the air compartment, where the concentrations are negligible. PECs in the water phase are in accordance with measured experimental concentrations in different European rivers. This case study shows that a simple level II fugacity model is suitable enough for modelling the environmental fate of high water soluble and low volatile organic compounds such as pharmaceuticals and personal care products.
Departament de Química, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain. xavier.domenech@uab.cat
Xavier
X
Domènech
José
J
Peral
Ivan
I
Muñoz
D003042:Cocaine / Q000031:analogs & derivatives* / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis*; D005544:Forecasting; D008956:Models, Chemical
D004785:Environmental Pollutants; C005618:benzoylecgonine; D003042:Cocaine