[Treatment of refractory status epilepticus with topiramate. Report of three cases].
Refractory status epilepticus is a catastrophic illness of the central nervous system, with a mortality rate that reaches 50%. We report three patients admitted with refractory status epilepticus: a 24 year-old male that discontinued antiepileptic medications, a 46 year-old male with a focal epilepsy secondary to an encephalitis that discontinued medications due to gastrointestinal problems and a 59 year-old male with an ischemic encephalopathy AH were treated with topiramate, delivered through a nasogastric tube with a good response.
Soler
Bernardita
B
Departamento de Neurología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago de Chile.
Godoy
Jaime
J
Mellado Talesnik
Patricio
P
D000284:Administration, Oral; D000927:Anticonvulsants / Q000627:therapeutic use; D005632:Fructose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications; D008297:Male; D008875:Middle Aged; D010352:Patient Dropouts; D013226:Status Epilepticus / Q000188:drug therapy* / Q000209:etiology; D000077236:Topiramate; D055815:Young Adult
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose