Lingual carcinoma metastases presenting as spontaneous pneumothorax.
Spontaneous pneumothorax is a rare manifestation of primary lung cancer or metastasis. We report a 39-year-old man with well-differentiated squamous cell carcinoma of the tongue and cervical lymph node metastases. He developed lung metastases and spontaneous pneumothorax 22 months later after intra-arterial infusion chemotherapy. The patient was managed with partial lung resection under thoracotomy. The pneumothorax resolved completely after the operation. Histological examination demonstrated metastatic squamous cell carcinoma, which had led to a bronchopleural fistula with subsequent induction of pneumothorax. The patient recovered uneventfully and continued to receive adjuvant chemotherapy in the oncology surgery outpatient department. Unfortunately, the tumors of the tongue and cervical lymph nodes progressively enlarged despite treatment. Eventually, the patient died of respiratory failure 5 months later. In most of the previously reported cases, pulmonary metastases associated with spontaneous pneumothorax usually originate from osteogenic or soft-tissue sarcomas. Although rare, pulmonary metastasis should be considered in the etiology of spontaneous pneumothorax. Despite advanced disease, surgical treatment may be feasible.
Hsu
Jui-Sheng
JS
Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chou
Shah-Hwa
SH
Tsai
Kun-Bow
KB
Chuang
Ming-Tsung
MT
D000328:Adult; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D011030:Pneumothorax / Q000209:etiology*; D014062:Tongue Neoplasms / Q000473:pathology*