New (9betaH)-lanostanes and lanostanes from Mikania aff. jeffreyi (Asteraceae).
Four new (9betaH)-lanostanes, i.e., (9betaH)-3beta-acetoxylanosta-7,24-diene, (9betaH)-3-oxolanosta-7,24-diene, (9betaH,24R)-3beta-acetoxy-24-hydroxylanosta-7,25-diene, and (9betaH,24S)-3beta-acetoxy-24-hydroxylanosta-7,25-diene, two new lanostanes, i.e., (24R)-3beta-acetoxy-24-hydroxylanosta-8,25-diene and (24S)-3beta-acetoxy-24-hydroxylanosta-8,25-diene, and two known lanostanes, i.e., 3beta-acetoxylanosta-8,24-diene and 3-oxolanosta-8,24-diene, were obtained from a new Mikania species (Asteraceae) besides pentacyclic triterpenes, steroids, and diterpenes. The structures of the compounds were determined by spectroscopic methods. This is the second study about acetyl-lanosterols from higher plants. Moreover, (9betaH)-lanostanes are very rare metabolites from dicotyledone angiosperms. The occurrence of these terpenes together in the same plant makes the species a good source for lanostane- and (9betaH)-lanostane-biosynthesis studies.
Mendes
Carla C
CC
Instituto de Química, Universidade Federal da Bahia, Campus Universitário de Ondina, CEP 40170-290, Salvador-Bahia, Brazil.
Sandes
Luciana Q
LQ
Cruz
Frederico G
FG
Roque
Nídia F
NF
D009682:Magnetic Resonance Spectroscopy; D035742:Mikania / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D014315:Triterpenes