The fascination of complex regional pain syndrome.
Complex regional pain syndrome (CRPS) is a pain disorder involving the somatosensory, the somatomotor and the sympathetic nervous systems. Based on experiments conducted by Bove (2009), it is suggested that changes in impulse activity in small-diameter afferents and postganglionic axons generated by neuritis can contribute to signs of early CRPS. The potential mechanisms involved are discussed. These mechanisms include the possibility that CRPS, a disorder of the central nervous system, may be caused by a nerve inflammation.
Jänig
Wilfrid
W
Physiologisches Institut, Christian-Albrechts-Universität zu Kiel, Kiel, Germany. w.janig@physiologie.uni-kiel.de
D000818:Animals; D001338:Autonomic Fibers, Postganglionic / Q000473:pathology* / Q000503:physiopathology*; D001369:Axons / Q000473:pathology / Q000502:physiology; D020918:Complex Regional Pain Syndromes / Q000209:etiology / Q000473:pathology*; D004195:Disease Models, Animal; D006801:Humans; D009443:Neuritis / Q000150:complications; D009474:Neurons / Q000473:pathology* / Q000502:physiology; D051381:Rats