[Adult-onset Still's disease with liver failure requiring liver transplantation].
We present the case of a 23-year-old man with fever of unknown origin, who developed acute liver failure 2 months after symptom onset, requiring an urgent liver transplantation. The diagnosis of adult-onset Still's disease was established after the reappearance of symptoms after transplantation, and high doses of corticosteroids were used to control disease activity. Subsequently, given the impossibility of tapering the steroid dose, interleukin-1 receptor blocking treatment was started with satisfactory outcome. We also review the published literature.
Terán
Alvaro
A
Servicio de Aparato Digestivo, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.
Casafont
Fernando
F
Fábrega
Emilio
E
Martínez-Taboada
Víctor Manuel
VM
Rodríguez-Valverde
Vicente
V
Pons-Romero
Fernando
F
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D004630:Emergencies; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein / Q000627:therapeutic use; D017093:Liver Failure / Q000209:etiology* / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D055815:Young Adult
D000305:Adrenal Cortex Hormones; D053590:Interleukin 1 Receptor Antagonist Protein