[Relationship between psychological distress and T lymphocyte in HIV/AIDS patients].
OBJECTIVE
To explore the relationship between psychological distress and T lymphocyte counts in HIV/AIDS patients.


METHODS
A total of 102 HIV/AIDS patients were measured by symptom check list (SCL-90), self-rating depressive scale (SDS) and self-rating anxiety scale (SAS). Patients were divided into 2 groups based on CD4+ T lymphocyte counts < 0.2 x 10(9)/L (group A) and > or = 0.2 x 10(9)/L(group B).


RESULTS
77 cases (75.49%) had psychological problems, including depression, relationship problems, psychosis, force etc. The prevalence of depression and anxiety were 67.65% (69/102) and 43.13% (44/102) respectively. The symptom of depression and anxiety of patients in group A were severer than those in group B (P < 0.05). The CD4+ T lymphocyte counts were significantly negatively correlated with the total score, depression score, paranoid score and psychosis score of SCL-90 (all P <0.05).


CONCLUSIONS
Most of the HIV/AIDS patients were in an obviously abnormal psychological status. The psychological distress symptom of HIV/AIDS patients might had negative effects on the number of CD4+ T lymphocyte.
Guangzhou No.8 People's Hospital, Guangzhou 510060, China.
Si-Han
SH
Lu
Xiao-Ping
XP
Tang
Xi-Long
XL
Deng
Wei-Lie
WL
Chen
Rong-Xin
RX
Hu
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000276:immunology / Q000523:psychology; D001007:Anxiety / Q000209:etiology; D018791:CD4 Lymphocyte Count; D003863:Depression / Q000209:etiology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000276:immunology* / Q000523:psychology*; D006801:Humans; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology*