Human Plasmodium knowlesi infection detected by rapid diagnostic tests for malaria.
We describe a PCR-confirmed case of Plasmodium knowlesi infection with a high parasitemia level and clinical signs of severe malaria in a migrant worker from Malaysian Borneo in the Netherlands. Investigations showed that commercially available rapid antigen tests for detection of human Plasmodium infections can detect P. knowlesi infections in humans.
Erasmus University Medical Center, Rotterdam, the Netherlands.
Jaap J
JJ
van Hellemond
Marijke
M
Rutten
Rob
R
Koelewijn
Anne Marie
AM
Zeeman
Jaco J
JJ
Verweij
Pieter J
PJ
Wismans
Clemens H
CH
Kocken
Perry J J
PJ
van Genderen
D000328:Adult; D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis; D001893:Borneo; D006801:Humans; D008288:Malaria / Q000175:diagnosis* / Q000469:parasitology; D008297:Male; D009426:Netherlands; D018512:Parasitemia / Q000175:diagnosis / Q000469:parasitology; D016790:Plasmodium knowlesi / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000379:methods; D011933:Reagent Kits, Diagnostic; D013045:Species Specificity; D013997:Time Factors; D014171:Transients and Migrants
D000953:Antigens, Protozoan; D011933:Reagent Kits, Diagnostic