title: [Valve-sparing aortic root replacement for young female patients with Marfan syndrome].
abstract: Annuloaortic ectasia is frequently related with Marfan syndrome, and Bentall procedure or aortic root replacement with valved conduit has been the conventional standard operation for this disease. Recently, some institutes have adopted valve-sparing aortic root replacement (VSARR) instead of Bentall procedure. Young female patients with Marfan syndrome who wishes for childbearing seem to be a group of good candidates of this type of operation, because it let them free from morbidities after artificial valve implantation. Valve-sparing operation should be taken into consideration when the size of Valsalva sinus reaches 45 mm for patients with Marfan syndrome and when it reaches 40 mm for patients with past histories or family histories of aortic dissection or aortic rupture. Since pregnancy is one of the most serious risk factors for aortic events, Valsalva sinus of 40 mm or larger could be the new standard for surgical indication if VSARR is applicable.
authors.affiliation: Department of Cardiothoracic Surgery, Tokyo University, Tokyo, Japan.
authors.forename: Kan
authors.initials: K
authors.lastname: Nawata
authors.forename: T
authors.initials: T
authors.lastname: Morota
mesh_terms: D000328:Adult; D001011:Aorta / Q000601:surgery*; D001021:Aortic Valve; D013504:Cardiovascular Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D008382:Marfan Syndrome / Q000601:surgery*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy