title: Design of membrane proteins: toward functional systems.
abstract: Over the years, membrane-soluble peptides have provided a convenient model system to investigate the folding and assembly of integral membrane proteins. Recent advances in experimental and computational methods are now being translated into the design of functional membrane proteins. Applications include artificial modulators of membrane protein function, inhibitors of protein-protein interactions, and redox membrane proteins.
authors.affiliation: Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85827, United States. gghirlanda@asu.edu
authors.forename: Giovanna
authors.initials: G
authors.lastname: Ghirlanda
mesh_terms: D000818:Animals; D015195:Drug Design; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism*; D010084:Oxidation-Reduction; D011485:Protein Binding; D017510:Protein Folding
chemical_list: D008565:Membrane Proteins