Carcinoma ex pleomorphic adenoma in a minor salivary gland: report of a case.
BACKGROUND
Carcinoma ex pleomorphic adenoma is exceedingly rare in minor salivary glands of the oral cavity. We present a case of carcinoma ex pleomorphic adenoma (CEPA) of the buccal mucosa in a 47-year-old Turkish patient. The buccal mass was of a size of 1.5 cm located in the left cheek. Pleomorphic adenoma was the tentative diagnosis.


METHODS
The tumor was removed under local anesthesia. Histopathologic evaluation revealed a preexisting pleomorphic adenoma associated with adenoid tumor component with tubulo-cystic and papillary or pseudopapillary structures; CEPA was diagnosed. Capsular integrity was incomplete with infiltration by islands of metaplastic/dysplastic epithelium.


RESULTS
Secondary surgery of the site was performed. No tumor tissue could be detected in the resection specimen. The patient is free of recurrence since 9 months.
Reichart
Peter A
PA
Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
Kalz
Steffen
S
Rabel
Annette
A
Bornstein
Michael M
MM
D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D002610:Cheek; D006801:Humans; D008046:Lip; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D012086:Reoperation; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D012470:Salivary Glands, Minor / Q000473:pathology* / Q000601:surgery