title: Essential oil composition and antioxidant capacity of Lippia schomburgkiana.
abstract: The leaves and fine stems of Lippia schomburgkiana recorded an essential yield of 1.8%, the main constituents of which were 1,8-cineole (64.1%) and alpha-terpineol (12.0%). The methanol extract of L. schomburgkiana inhibited the DPPH radical, resulting in an EC50 value of 16.1 +/- 0.7 microg x mL(-1), which is only three times lower than that of trolox (4.7 +/- 0.4 microg x mL(-1)), signifying a high antioxidant activity for the species. The amount of total phenolics (376.7 +/- 35.5 mg GAE/g) and the trolox equivalent antioxidant capacity (327.0 +/- 24.8 mg TE/g) of the methanol extract confirmed the significant antioxidative capacity of this plant. The brine shrimp bioassay carried out on the oil (49.6 +/- 0.4 microg x mL(-1)) showed high toxicity, providing important evidence of its biological activity. The sensory evaluation of the leaves of L. schomburgkiana showed a percentage acceptance value very close to commercial oregano, indicating that the plant can be used in spice and condiment products.
authors.affiliation: Programa de Pós-Graduação em Química, Universidade Federal do Pará, 66075-900 Belém, PA, Brazil.
authors.forename: Nathalie A
authors.initials: NA
authors.lastname: da Silva
authors.forename: Joyce Kelly R
authors.initials: JK
authors.lastname: da Silva
authors.forename: Eloisa Helena A
authors.initials: EH
authors.lastname: Andrade
authors.forename: Lea Maria M
authors.initials: LM
authors.lastname: Carreira
authors.forename: Pergentino José C
authors.initials: PJ
authors.lastname: Sousa
authors.forename: José Guilherme S
authors.initials: JG
authors.lastname: Maia
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001156:Artemia; D001713:Biphenyl Compounds / Q000378:metabolism; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007928:Lethal Dose 50; D032411:Lippia / Q000737:chemistry*; D008297:Male; D051379:Mice; D009822:Oils, Volatile / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010851:Picrates / Q000378:metabolism; D035261:Plant Components, Aerial / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*; D013047:Specific Pathogen-Free Organisms; D013649:Taste; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018675:Toxicity Tests
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D009822:Oils, Volatile; D010636:Phenols; D010851:Picrates; D010938:Plant Oils; D013729:Terpenes; C004931:1,1-diphenyl-2-picrylhydrazyl