title: Irritable bowel syndrome and chronic constipation in patients with endometriosis.
abstract: OBJECTIVE
  The aim of this study was to evaluate how many patients with endometriosis have concomitant irritable bowel syndrome (IBS) and/or constipation according to the Rome III criteria. Furthermore, the value of an additional gastroenterological consultation with therapeutic advice was evaluated.
  
  
  METHODS
  Patients with proven endometriosis were included in a prospective, single-centre study. A questionnaire was undertaken regarding IBS and chronic constipation. Patients with symptoms consistent with the Rome III criteria for IBS were referred to our gastroenterological outpatient clinic.
  
  
  RESULTS
  In total 101 patients were included. Endometriosis was diagnosed surgically in 97% and visually in the vagina in 3%. Fifteen per cent of the patients with endometriosis also had IBS and 14% of the patients with endometriosis had functional constipation without IBS. Of the 22 patients finally presenting to the gastroenterologist, five had a significant stenotic rectosigmoid lesion and were treated surgically. The remaining 17 patients were treated conservatively. Defecation symptoms improved in 86% and pain was reduced in 64%.
  
  
  CONCLUSIONS
  In patients with endometriosis, 29% also had IBS or constipation. Referral to a gastroenterologist resulted in improvement of defaecation in 86%, and 64% reported a reduction in the degree of pain.
authors.affiliation: Department of Gastroenterology and Hepatology, VU Medical Centre, Amsterdam, the Netherlands. M.Szojda@vumc.nl
authors.forename: M M
authors.initials: MM
authors.lastname: Meurs-Szojda
authors.forename: V
authors.initials: V
authors.lastname: Mijatovic
authors.forename: R J F
authors.initials: RJ
authors.lastname: Felt-Bersma
authors.forename: P G A
authors.initials: PG
authors.lastname: Hompes
mesh_terms: D000328:Adult; D003248:Constipation / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D004715:Endometriosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D016896:Treatment Outcome