title: Immune thrombocytopenic purpura associated with pulmonary tuberculosis.
abstract: Over the past decade, tuberculosis has been recognized worldwide as a public health problem of increasing proportions. We report a patient who presented with epistaxis and generalized petechiae. The diagnosis was immune thrombocytopenia and the patient was treated with intravenous immunoglobulin and pulse steroid. The bleeding continued and thrombocyte level was low despite therapy. Chest X-ray and a computed tomography scan of the thorax showed right upper lobe opacities and bilateral interstitial infiltrates. The patient also had a history of close contact with an individual with active tuberculosis. The thrombocytopenia was resistant to standard therapy, but resolved after antituberculosis treatment. This report is the first case of a child with immune thrombocytopenia secondary to pulmonary tuberculosis.
authors.affiliation: Department of Pediatric Intensive Care, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Başak
authors.initials: B
authors.lastname: Akyildiz
authors.forename: Nedret
authors.initials: N
authors.lastname: Uzel
authors.forename: Diana
authors.initials: D
authors.lastname: Yanni
authors.forename: Agop
authors.initials: A
authors.lastname: Citak
authors.forename: Metin
authors.initials: M
authors.lastname: Karaböcüoğlu
authors.forename: Raif
authors.initials: R
authors.lastname: Uçsel
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D002675:Child, Preschool; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage; D007262:Infusions, Intravenous; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D010976:Platelet Count; D020551:Pulse Therapy, Drug; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D005938:Glucocorticoids; D007136:Immunoglobulins; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin