title: Reduced interhemispheric coherence in dyslexic adults.
abstract: BACKGROUND
  Developmental dyslexia has been associated with reduced interhemispheric neural connectivity in children. The present study investigated functional interhemispheric connectivity in male dyslexic adults.
  
  
  METHODS
  A group of 19 dyslexic men were compared to a group of 15 controls on interhemispheric coherence of the dominant frequency in the power spectrum during a visuo-spatial attention task. The coherence between a left hemisphere central-parietal electrode and the respective right hemisphere electrode and surrounding sites was analysed.
  
  
  RESULTS
  Compared to controls, the dyslexic group demonstrated reduced, and more diffuse, interhemispheric coherence of alpha activity in the central-parietal cortex. No group differences in interhemispheric coherence were found on frontal, temporal or central sites.
  
  
  CONCLUSIONS
  The deviant pattern of functional connectivity in dyslexics is suggestive of an altered development of neural circuitry that may lead to deficits in magnocellular processing.
authors.affiliation: BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands. Monica.Dhar@UGent.be
authors.forename: Monica
authors.initials: M
authors.lastname: Dhar
authors.forename: Pieter H
authors.initials: PH
authors.lastname: Been
authors.forename: Ruud B
authors.initials: RB
authors.lastname: Minderaa
authors.forename: Monika
authors.initials: M
authors.lastname: Althaus
mesh_terms: D000328:Adult; D000513:Alpha Rhythm; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D004410:Dyslexia / Q000503:physiopathology*; D004569:Electroencephalography; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D013028:Space Perception / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult