title: [Wavefront-guided Lasik for low to moderate myopia: CustomCornea versus Zyoptix].
abstract: OBJECTIVE
  To compare the visual and clinical outcomes of Wavefront-guided laser in situ keratomileusis (Lasik) with Alcon CustomCornea and Zyoptix systems.
  
  
  METHODS
  A prospective, randomized, masked and bilateral study was conducted. Fifty patients with preoperative spherical equivalent ranging from -1.00 to -6.50 D were enrolled for customized ablation in both eyes. All of them were submitted to Lasik CustomCornea treatment in one eye and Zyoptix in the other eye. Uncorrected visual acuity, best correct visual acuity (BCVA), manifest refraction, wavefront measurements, and contrast sensitivity testing were performed preoperatively and postoperatively at 1, 3 and 6 months.
  
  
  RESULTS
  Preoperatively manifest refractive spherical equivalent was -3.29+/-1.56 D in the CustomCornea group and -3.22+/-1.50 D in the Zyoptix group. At 6 months, 86% of CustomCornea eyes and 70% of Zyoptix eyes had UCVA>or=20/20. One hundred percent of the CustomCornea group and 88% of the eyes in the Zyoptix were within 0.50 D of emmetropia. In both groups, the contrast sensitivity improved. Spherical aberration increased in both groups, with the CustomCornea group showing lower levels (p<0.001).
  
  
  CONCLUSIONS
  There were no differences between the systems according to safety and effectiveness. The Zyoptix platform showed greater spherical aberration.
authors.affiliation: Eye Clinic Day Hospital, São Paulo, SP, Brazil. telma.pereira@uol.com.br
authors.forename: Telma Pereira
authors.initials: TP
authors.lastname: Barreiro
authors.forename: Adriana dos Santos
authors.initials: Ados S
authors.lastname: Forseto
authors.forename: Lucila Ferreira Leite
authors.initials: LF
authors.lastname: Pinto
authors.forename: Claudia Maria
authors.initials: CM
authors.lastname: Francesconi
authors.forename: Walton
authors.initials: W
authors.lastname: Nosé
mesh_terms: D000328:Adult; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D009216:Myopia / Q000601:surgery*; D011446:Prospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult