Community attitudes towards emergency research and exception from informed consent.
OBJECTIVE
To determine public attitudes towards emergency research, exception from informed consent (EFIC) and a specific proposed clinical trial using EFIC.


METHODS
As part of a planned community consultation activity, a survey was conducted at a popular public venue. Participants answered demographic questions and then were asked their opinions on specifically described consent circumstances in emergency research, including the proposed EFIC trial. Multiple logistic and linear regression were used to determine respondent characteristics associated with specific attitudes.


RESULTS
1901 surveys were completed. The majority of respondents supported emergency research (88%) and the concept of surrogate consent by a legally authorized representative (78%). The concept of EFIC was less well supported (35%) but the application of EFIC was more accepted, especially when EFIC was applied to the respondent themselves (51%). The community believed the proposed EFIC study was acceptable (82%); a minority had concerns but most were related to patient safety and not to EFIC. Respondents with less education and lower incomes were less likely to express opinions about the consent and research concepts described.


CONCLUSIONS
Emergency research and the proposed EFIC trial is supported in this community. The concept of EFIC is less well supported but is more acceptable when a specific trial is described or when respondents consider EFIC for themselves. Specific respondent characteristics are associated with attitudes about research; this can assist in development of meaningful community consultation activities.
Biros
Michelle H
MH
University of Minnesota, Department of Emergency Medicine, 717 Delaware Avenue, Minneapolis, MN 55415, United States. Biros001@umn.Edu
Sargent
Corey
C
Miller
Kathleen
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D035843:Biomedical Research; D002986:Clinical Trials as Topic; D004522:Educational Status; D004635:Emergency Medicine; D005260:Female; D006801:Humans; D007182:Income; D007258:Informed Consent; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011639:Public Opinion; D011795:Surveys and Questionnaires