title: Chiral salen Mn(III) complex-based enantioselective potentiometric sensor for L-mandelic acid.
abstract: A new enantioselective potentiometric sensor containing chiral salen Mn(III) as the chiral selector was designed for the assay of L-mandelic acid (L-MA). Optimized membrane electrodes displayed linear dynamic range from 1x10(-5) to 1x10(-1) mol L(-1) with a detection limit of 7.2x10(-6) mol L(-1) and a Nernstian response of -58.1+/-0.5 mV decade(-1) towards L-MA within pH range 7.0-10.2. The potentiometric enantioselectivity coefficient (logK(L,D)(Pot)) of this sensor was -4.0, indicating that the chiral salen Mn(III) complex-based electrode exhibited fairly good discrimination toward L-MA over counter isomer D-MA. The mechanism of chiral recognition for L-MA is discussed by using HF/STO-3G calculation method simulation.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Beibei Tiansheng Road 2#, Chongqing 400715, PR China. xulan@swu.edu.cn
authors.forename: Lan
authors.initials: L
authors.lastname: Xu
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Yang
authors.forename: Yaqiong
authors.initials: Y
authors.lastname: Wang
authors.forename: Jiuzhi
authors.initials: J
authors.lastname: Gao
mesh_terms: D004563:Electrochemistry; D004566:Electrodes; D005029:Ethylenediamines / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008333:Mandelic Acids / Q000032:analysis*; D008345:Manganese / Q000737:chemistry*; D008567:Membranes, Artificial; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D011199:Potentiometry; D013237:Stereoisomerism
chemical_list: D005029:Ethylenediamines; D008333:Mandelic Acids; D008567:Membranes, Artificial; D009942:Organometallic Compounds; D008345:Manganese; C011452:disalicylaldehyde ethylenediamine; C037938:mandelic acid