Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70.
van Eden
Willem
W
D000818:Animals; D004224:Diterpenes / Q000494:pharmacology / Q000627:therapeutic use*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000188:drug therapy*; D004852:Epoxy Compounds / Q000494:pharmacology / Q000627:therapeutic use; D005786:Gene Expression Regulation / Q000187:drug effects; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D007166:Immunosuppressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D051379:Mice; D010616:Phenanthrenes / Q000494:pharmacology / Q000627:therapeutic use*
D004224:Diterpenes; D004852:Epoxy Compounds; D018840:HSP70 Heat-Shock Proteins; D007166:Immunosuppressive Agents; D010616:Phenanthrenes; C001899:triptolide