title: Saline infusion sonohysterography - an effective tool for evaluation of the endometrial cavity in women with abnormal uterine bleeding.
abstract: We evaluated the diagnostic accuracy of saline infusion sonohysterography (SISH) over transvaginal sonography (TVS) for the detection of intrauterine abnormalities using hysteroscopy as the gold standard in a retrospective study of 70 women mostly presenting with abnormal uterine bleeding. TVS was normal in 32 women, while in the others polyps or fibroids projecting into the cavity (n = 19) or a thick endometrium (n = 19) were suspected. On performing SISH the uterine cavity was found to be normal in 29 women, while 35 had suspected polyps/fibroids and 6 had other abnormalities. Hysteroscopy proved to be normal in 28 women, 35 had polyps/fibroids and 7 had other abnormalities. The sensitivity, specificity, positive and negative predictive values for TVS were 72.4%, 100%, 100% and 74%, respectively, while for SISH the corresponding figures were 91.4%, 92.6%, 89.3% and 94.1%. SISH is a simple, minimally invasive and cost-effective investigative tool enhancing the diagnostic accuracy of TVS and can be an effective screening test prior to hysteroscopy.
authors.affiliation: Department of Obstetrics and Gynecology, Sultan Qaboos University, Muscat, Oman.
authors.forename: Mariam
authors.initials: M
authors.lastname: Mathew
authors.forename: Vaidyanathan
authors.initials: V
authors.lastname: Gowri
authors.forename: Syed Gauhar
authors.initials: SG
authors.lastname: Rizvi
mesh_terms: D004714:Endometrial Hyperplasia / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000379:methods*; D015907:Hysteroscopy; D007889:Leiomyoma / Q000000981:diagnostic imaging; D008595:Menorrhagia / Q000000981:diagnostic imaging*; D008796:Metrorrhagia / Q000000981:diagnostic imaging*; D011127:Polyps / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000008:administration & dosage; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging; D014621:Vagina / Q000000981:diagnostic imaging
chemical_list: D012965:Sodium Chloride