Fertility preservation: definition, history, and prospect.
Exposure to gonadotoxic agents for treating cancer and other diseases or postponement of maternity jeopardize the prospects of genetic parenthood and are major factors driving the development of fertility preservation technologies. Although its mainstays, cryopreservation and vitrification, have been adopted from infertility medicine for fertility preservation purposes, there is a need for additional specialized procedures, protocols, and biomedical devices. As its multidisciplinary character and aims diverge compared with other branches of reproductive medicine, we are witnessing the emergence of a field in its own right.
Gosden
Roger G
RG
Ronald O Perelman & Claudia Cohen Center for Reproductive Medicine & Infertility, Weill Medical College of Cornell University, New York, New York 10021, USA. Rgg2004@med.cornell.edu
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects; D015925:Cryopreservation; D005260:Female; D005298:Fertility / Q000187:drug effects / Q000528:radiation effects; D049673:History, 20th Century; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000266:history / Q000503:physiopathology / Q000517:prevention & control*; D007248:Infertility, Male / Q000209:etiology / Q000266:history / Q000503:physiopathology / Q000517:prevention & control*; D008297:Male; D054315:Oocyte Retrieval; D010062:Ovulation Induction; D011878:Radiotherapy / Q000009:adverse effects; D027724:Reproductive Techniques, Assisted / Q000266:history; D012662:Semen Preservation; D013074:Sperm Banks
D000970:Antineoplastic Agents