title: Persistent intermediate uveitis associated with latent manifestation of facial large B-cell non-Hodgkin lymphoma.
abstract: OBJECTIVE
  To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy.
  
  
  METHODS
  Retrospective, interventional case report.
  
  
  METHODS
  A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive.
  
  
  RESULTS
  Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity.
  
  
  CONCLUSIONS
  NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.
authors.affiliation: Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
authors.forename: E Jason
authors.initials: EJ
authors.lastname: Sabet-Peyman
authors.forename: Charles G
authors.initials: CG
authors.lastname: Eberhart
authors.forename: Kashif
authors.initials: K
authors.lastname: Janjua
authors.forename: Syed Mahmood
authors.initials: SM
authors.lastname: Shah
authors.forename: Diana V
authors.initials: DV
authors.lastname: Do
authors.forename: Quan Dong
authors.initials: QD
authors.lastname: Nguyen
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005153:Facial Neoplasms / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000150:complications* / Q000188:drug therapy; D012189:Retrospective Studies; D016896:Treatment Outcome; D015867:Uveitis, Intermediate / Q000209:etiology*