NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives.
The 1H and 13C NMR resonances of 22 5-(5-substituted-2-nitrophenyl)-1H-pyrrole-2-carboxamides, 22 5-(5-substituted-2-aminophenyl)-1H-pyrrole-2-carboxamides, and 9 5-phenyl-1H-pyrrole-2-carboxamides were assigned completely using the concerted application of one- and two-dimensional experiments (DEPT, gs-HMQC and gs-HMBC). NOE studies and conformational analysis confirm the preferred conformations of such compounds.
López-Cara
Luisa C
LC
Departamento de Química Farmacéutica y Orgánica, Facultad de Farmacia, Universidad de Granada, 18071 Granada, Spain.
Pineda de las Infantas
M José
MJ
Carrión
M Dora
MD
Camacho
M Encarnación
ME
Gallo
Miguel A
MA
Espinosa
Antonio
A
Entrena
Antonio
A
D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011522:Protons; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D012015:Reference Standards; D013237:Stereoisomerism
D002247:Carbon Isotopes; D011522:Protons; D011720:Pyrazoles