Degradation of sulfur mustard on KF/Al2O3 supports: insights into the products and the reactions mechanisms.
The degradation of the warfare agent sulfur mustard (HD) adsorbed onto KF/Al(2)O(3) sorbents is described. These processes were explored by MAS NMR, using (13)C-labeled sulfur mustard (HD*) and LC-MS techniques. Our study on the detoxification of this blister agent showed the formation of nontoxic substitution and less-toxic elimination products (t(1/2) = 3.5-355 h). Interestingly, the reaction rates were found to be affected by MAS conditions, i.e., by a centrifugation effect. The products and the mechanisms of these processes are discussed.
Zafrani
Yossi
Y
Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona 74100, Israel. yossiz@iibr.gov.il
Goldvaser
Michael
M
Dagan
Shai
S
Feldberg
Liron
L
Mizrahi
Dana
D
Waysbort
Daniel
D
Gershonov
Eytan
E
Columbus
Ishay
I
D000537:Aluminum Oxide / Q000737:chemistry*; D002853:Chromatography, Liquid; D005459:Fluorides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009151:Mustard Gas / Q000737:chemistry*; D017680:Potassium Compounds / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D017680:Potassium Compounds; C033320:potassium fluoride; D000537:Aluminum Oxide; D005459:Fluorides; D009151:Mustard Gas