title: Which is the single most important factor in deciding the management and determining the prognosis of head and neck cancer?
authors.forename: Alfio
authors.initials: A
authors.lastname: Ferlito
authors.forename: Robert P
authors.initials: RP
authors.lastname: Takes
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rinaldo
authors.forename: Kenneth O
authors.initials: KO
authors.lastname: Devaney
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003661:Decision Support Techniques; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010039:Otorhinolaryngologic Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D011379:Prognosis; D015996:Survival Rate; D047368:Tumor Burden