Mitosis: KLP61F goes wee!
Kinesin-5s help assemble the bipolar spindle by crosslinking and sliding apart antiparallel microtubules. A recent study has uncovered a novel pathway for the phospho-regulation of these motors.
Sharp
David J
DJ
Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461, USA. dsharp@aecom.yu.edu
Rath
Uttama
U
D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism; D004330:Drosophila / Q000378:metabolism / Q000502:physiology; D029721:Drosophila Proteins / Q000378:metabolism; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D008938:Mitosis / Q000502:physiology; D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000378:metabolism; D009687:Nuclear Proteins / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D008941:Spindle Apparatus / Q000502:physiology
D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; C084034:Klp61F protein, Drosophila; D008869:Microtubule-Associated Proteins; D020409:Molecular Motor Proteins; D009687:Nuclear Proteins; D011505:Protein-Tyrosine Kinases; C508847:Wee1 protein, Drosophila