Synthesis and reactivity of beta-methoxymethyl enecarbamates.
Beta-methoxymethyl enecarbamates (e.g., 1) have been prepared in a single step from alpha-methoxy carbamates. In the presence of a mild Lewis acid, compound 1 underwent substitution with a variety of nucleophiles including indoles, electron-rich aromatics, silyl enol ethers, and 2-trimethylsilyloxyfuran.
O'Connor
Patrick D
PD
Department of Chemistry, The University of Auckland, 23 Symonds Street, Auckland, New Zealand.
Marino
Michael G
MG
Guéret
Stéphanie M
SM
Brimble
Margaret A
MA
D002219:Carbamates / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D002219:Carbamates