title: Pearly penile papules regress in older patients and with circumcision.
abstract: This study assesses the prevalence and correlates of pearly penile papules (PPP) in two non-genitourinary (GU) medicine male cohorts (<25 and >50 years). PPP were categorised in 188 university students (<25 years), based on self-examination, and 70 patients (>50 years), based on clinician examination. PPP were categorised from 1 to 4, based on increasing papule size and distribution. An anonymous questionnaire was used to identify associations with PPP prevalence. The prevalence of PPP was 38.3% in <25 years, and 11.4% in >50 years (P < 0.001). The prevalence of categories 3 and 4 PPP was 8.5% in <25 years, and 1.4% in >50 years (P < 0.05). In the younger age group, the prevalence of PPP was 26.5% in circumcised participants, and 42.4% in uncircumcised participants (P < 0.05), but was unrelated to either frequency of sexual intercourse or time since first sexual intercourse. In conclusion, PPP disappear with age, and any PPP in patients >50 years are less marked than those in patients <25 years. Patients should be advised accordingly. PPP are less prevalent in circumcised men. Patients could be advised to wear the foreskin rolled back - this may maximize exposure of the coronal area to normal abrasion, which may hasten PPP regression.
authors.affiliation: University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.
authors.forename: K
authors.initials: K
authors.lastname: Agha
authors.forename: S
authors.initials: S
authors.lastname: Alderson
authors.forename: S
authors.initials: S
authors.lastname: Samraj
authors.forename: A
authors.initials: A
authors.lastname: Cottam
authors.forename: C
authors.initials: C
authors.lastname: Merry
authors.forename: V
authors.initials: V
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Patel
mesh_terms: D000328:Adult; D000367:Age Factors; D002944:Circumcision, Male; D015331:Cohort Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009365:Neoplasm Regression, Spontaneous; D010412:Penile Neoplasms / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D011795:Surveys and Questionnaires; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult