title: Role of extracellular adenosine in acute lung injury.
abstract: Acute lung injury (ALI) is a lung disease characterized by pulmonary edema and severe hypoxia. The past decade hosted a search for endogenous mechanisms controlling lung inflammation and pulmonary edema during ALI. As such, recent evidence indicates extracellular adenosine in orchestrating the resolution of pulmonary edema and inflammation during ALI.
authors.affiliation: Department of Anesthesiology, Mucosal Inflammation Program, University of Colorado Denver, Aurora, Colorado, USA.
authors.forename: Tobias
authors.initials: T
authors.lastname: Eckle
authors.forename: Michael
authors.initials: M
authors.lastname: Koeppen
authors.forename: Holger K
authors.initials: HK
authors.lastname: Eltzschig
mesh_terms: D000241:Adenosine / Q000502:physiology*; D000818:Animals; D002196:Capillaries / Q000502:physiology; D005110:Extracellular Space / Q000502:physiology*; D006801:Humans; D008171:Lung Diseases / Q000473:pathology*; D009711:Nucleotides / Q000378:metabolism; D011650:Pulmonary Alveoli / Q000502:physiology; D043705:Receptor, Adenosine A2A / Q000502:physiology; D043704:Receptor, Adenosine A2B / Q000502:physiology
chemical_list: D009711:Nucleotides; D043705:Receptor, Adenosine A2A; D043704:Receptor, Adenosine A2B; D000241:Adenosine