Secondary amyloidosis associated with multiple sclerosis.
BACKGROUND
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS.


METHODS
A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS.


CONCLUSIONS
This is the first report of secondary amyloidosis associated with MS.
Kang
Seok Jae
SJ
Department of Neurology, Hanyang University College of Medicine, Guri, Korea.
Yi
Joo-Hark
JH
Hong
Hyun-Seok
HS
Jang
Si-Hyung
SH
Park
Moon-Hyang
MH
Kim
Ho-Jung
HJ
Lee
Kyu-Yong
KY
Lee
Young-Joo
YJ
Han
Sang-Woong
SW
Koh
Seong-Ho
SH