Synthesis and biological activity of novel oxazolidinones.
A number of 5-substituted derivatives of Ranbezolid, a novel oxazolidinone were synthesized. Antibacterial activity of the compounds against a number of sensitive and resistant bacteria showed promising results.
Das
Biswajit
B
Department of Medicinal Chemistry, New Drug Discovery Research, Ranbaxy Research Laboratories, Plot-20, Sector-18, Udyog Vihar, Gurgaon 122001, India. biswajit.das@ranbaxy.com
Rajarao
A V S
AV
Rudra
Sonali
S
Yadav
Ajay
A
Ray
Abhijit
A
Pandya
Manisha
M
Rattan
Ashok
A
Mehta
Anita
A
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D001419:Bacteria; D015195:Drug Design; D005663:Furans; D008826:Microbial Sensitivity Tests; D010080:Oxazoles; D023303:Oxazolidinones / Q000138:chemical synthesis / Q000494:pharmacology*; D020713:Vancomycin Resistance
D000900:Anti-Bacterial Agents; D005663:Furans; D010080:Oxazoles; D023303:Oxazolidinones; C476340:ranbezolid