Solvent-free direct reductive amination by catalytic use of an organotin reagent incorporated on an ionic liquid.
An organotin reagent supported on an ionic liquid was used as a highly effective catalyst (down to 0.1 mol%) for the direct reductive amination of aldehydes and ketones using PhSiH3; this solvent-free method facilitates purification of the products, thus minimizing the contamination by tin.
Pham
Phuoc Dien
PD
Laboratoire de Synthèse Organique, UCO2M, UMR CNRS 6011, Université du Maine, Avenue Olivier Messiaen, 72085 Le Mans Cedex 9, France.
Bertus
Philippe
P
Legoupy
Stéphanie
S
D000447:Aldehydes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D052578:Ionic Liquids / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D014001:Tin / Q000737:chemistry*
D000447:Aldehydes; D052578:Ionic Liquids; D007659:Ketones; D014001:Tin