title: [Genetic polymorphism of CYP-450 in drug development].
authors.affiliation: nonen@phs.osaka-u.ac.jp
authors.forename: Shinpei
authors.initials: S
authors.lastname: Nonen
authors.forename: Junichi
authors.initials: J
authors.lastname: Azuma
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics* / Q000378:metabolism; D017321:Clinical Trials, Phase I as Topic; D065731:Cytochrome P-450 CYP2C19; D065729:Cytochrome P-450 CYP2C9; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism; D055808:Drug Discovery; D010597:Pharmacogenetics; D010599:Pharmacokinetics; D011110:Polymorphism, Genetic; D057285:Precision Medicine
chemical_list: C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D019389:Cytochrome P-450 CYP2D6