MRI-guided focused ultrasound treatments.
Focused ultrasound (FUS) allows noninvasive focal delivery of energy deep into soft tissues. The focused energy can be used to modify and eliminate tissue for therapeutic purposes while the energy delivery is targeted and monitored using magnetic resonance imaging (MRI). MRI compatible methods to deliver these exposures have undergone rapid development over the past 10 years such that clinical treatments are now routinely performed. This paper will review the current technical and clinical status of MRI-guided focused ultrasound therapy and discuss future research and development opportunities.
Hynynen
Kullervo
K
Sunnybrook Health Sciences Centre, Imaging Research, Department of Medical Biophysics, University of Toronto, 2075 Bayview Ave., Toronto, ON, Canada M4N 3M5. khynynen@sri.utoronto.ca
D016503:Drug Delivery Systems; D005544:Forecasting; D015316:Genetic Therapy; D006801:Humans; D006979:Hyperthermia, Induced; D053783:Magnetic Resonance Imaging, Interventional; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D015912:Thrombolytic Therapy; D014464:Ultrasonic Therapy / Q000379:methods*; D014463:Ultrasonography