title: [A comparative study of PTT and CT tests for coagulation evaluation of cardiovascular system external communicating devices].
abstract: Based on GB/T16886.4-2003 Standard, the coagulation effects of 5 cardiovascular system external communicating devices made consist of metal and polymer were assessed using the partial thromboplastin time (PTT) and Lee-White coagulation time (CT) tests. The results indicate that PTT test is a stable and valuble method for evaluating the coagulating pathway disturbance of the devices. In line with GB/T 16886.4-2003 Standard, PTT test is a recommendable method for evaluating the external communicating devices Based on GB/T14233.2-2005 Standard, CT test is a method more liable to variation, compared with PTT test. This is due to the complex relativity in the test itself, due to all the factors of coagulating cascade, and due to the individual difference of animal. The question of how to select proper negative control for coagulation evaluation of the Cardiovascular System External Communicating Devices in clinical setting for CT test should be addressed and studied.
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
authors.forename: Tun
authors.initials: T
authors.lastname: Yuan
authors.forename: Jing
authors.initials: J
authors.lastname: San
authors.forename: Liping
authors.initials: L
authors.lastname: Zheng
authors.forename: Weijing
authors.initials: W
authors.lastname: Zhu
authors.forename: Jie
authors.initials: J
authors.lastname: Liang
mesh_terms: D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002309:Cardiology / Q000295:instrumentation*; D004869:Equipment Safety; D006801:Humans; D008670:Metals / Q000009:adverse effects; D010314:Partial Thromboplastin Time; D011108:Polymers / Q000009:adverse effects; D011300:Preoperative Care
chemical_list: D008670:Metals; D011108:Polymers