title: [Study of the microbial spectrum of ulcerative-and-necrotic lesions in gerontological patients with lower limb chronic ischaemia].
abstract: The present work deals with a comprehensive study of the microbial spectrum of an ischaemic trophic ulcer in gerontological patients with degree IV lower limb chronic ischaemia in order to improve therapeutic outcomes by means of selecting individual antibacterial therapy for a possible prognosis of the results of treatment for an ulcerative-and-necrotic lesion of distal portions of the lower extremities depending on the spectrum of the microflora vegetating in the wound. Based on examining a total of 130 patients aged 70 years and older suffering from lower limb chronic critical ischaemia, we revealed that the pathogen of secondary wound infection isolated in trophic ulcers of the lower extremities influences the total outcomes of surgical management. A conclusion was made on the necessity of a compulsory dynamic scrutiny of the microbial flora of the lower-limb atherosclerotic ulcer, which makes it possible to carefully select individual antibacterial bactericidal therapy with due regard for microbial sensitivity to bactericidal agents.
authors.forename: N B
authors.initials: NB
authors.lastname: Ismailov
authors.forename: A V
authors.initials: AV
authors.lastname: Vesnin
mesh_terms: D000367:Age Factors; D000368:Aged; D001162:Arteriosclerosis Obliterans / Q000382:microbiology* / Q000473:pathology; D001419:Bacteria / Q000302:isolation & purification*; D002908:Chronic Disease; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D007511:Ischemia / Q000382:microbiology* / Q000473:pathology; D007866:Leg / Q000098:blood supply* / Q000382:microbiology / Q000473:pathology; D007871:Leg Ulcer / Q000382:microbiology* / Q000473:pathology; D008828:Microbiological Techniques; D009336:Necrosis