title: [35-year experience in research of peptide regulation of aging].
abstract: The results of 35-year-long studies on mechanisms of aging and on efficacy of peptide bioregulators in prevention of age-related pathology are presented in this review paper. The data have been obtained with most advanced methods in collaboration with research laboratories of Russia, USA, UK, Germany, Italy, Spain, France. The molecular model of complementary interrelation of short peptides with promoter site of genes which is a background of protein biosynthesis initiation has been suggested. The prospects of clinical use of peptide bioregulators for prevention of premature aging of the active population in Russia are discussed.
authors.forename: V Kh
authors.initials: VKh
authors.lastname: Khavinson
authors.forename: V N
authors.initials: VN
authors.lastname: Anisimov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000187:drug effects* / Q000502:physiology; D019588:Aging, Premature / Q000188:drug therapy; D000818:Animals; D006801:Humans; D008875:Middle Aged; D009842:Oligopeptides / Q000627:therapeutic use*
chemical_list: D009842:Oligopeptides