Effect of biomedical organic compounds on the setting reaction of calcium phosphates.
In the present study, the effect of biomedical organic compounds (starch, sodium alginate, chitosan and gelatin) on the hydration of calcium phosphates was studied using X-ray diffraction, infrared spectroscopy, scanning electron microscopy and XPS analysis. Amorphous calcium phosphate (ACP) was prepared by a mechanochemical route and mixed with biomedical organic compounds. A solidification reaction occurred between ACP and dicalcium phosphate dihydrate (DCPD); the hydration product was poorly crystallized hydroxyapatite (HA). During the setting reaction of ACP and DCPD, the presence of biomedical organic compounds had an effect on the hydration product: the bonding energies of the primary elements (Ca, P) in the hydration product (HA) were changed; also different hydration morphologies, self-setting properties, rheological properties and mechanical strength of the cement were obtained. This work will allow advances in the synthesis of bionic composite calcium phosphate cement (CPC).
Yu
Tao
T
Key Laboratory of Specially Functional Materials of Ministry of Education and School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China.
Ye
Jiandong
J
Gao
Chengying
C
Yu
Long
L
Wang
Yingjun
Y
D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength / Q000187:drug effects; D003738:Dental Cements / Q000737:chemistry; D005780:Gelatin / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D009930:Organic Chemicals / Q000494:pharmacology*; D056951:Photoelectron Spectroscopy; D011134:Polysaccharides / Q000494:pharmacology*; D012212:Rheology / Q000187:drug effects; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014961:X-Ray Diffraction
D002130:Calcium Phosphates; D003738:Dental Cements; D009930:Organic Chemicals; D011134:Polysaccharides; D005780:Gelatin