title: A renal mass in a patient with melanoma.
abstract: A 61-year-old man presented to the emergency room with significant weight loss. Laboratory analysis revealed elevations in blood urea nitrogen, creatinine, and white blood cell count. Computed tomography imaging showed a large, infiltrative mass in the right renal vein, with metastasis to the brain. Biopsy of soft tissue mass and kidney revealed positive staining for malignant melanoma. Malignant melanoma to the kidney is extremely rare, and imaging modalities alone cannot differentiate neoplasms in the kidney. It is therefore necessary to use specific immunocytochemical staining along with imaging modalities to make a specific diagnosis when the primary origin of the tumor is unknown.
authors.affiliation: Hematology and Medical Oncology, Fairview Hospital, Moll Pavilion, Cleveland Clinic Foundation, OH 44111, USA.
authors.forename: Kirsten M
authors.initials: KM
authors.lastname: Boughan
authors.forename: Sebouh
authors.initials: S
authors.lastname: Setrakian
authors.forename: Chi Hoon
authors.initials: CH
authors.lastname: Lee
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Spiro
authors.forename: Hamed A
authors.initials: HA
authors.lastname: Daw
mesh_terms: D000368:Aged; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D003404:Creatinine