title: Assessment of ovarian stromal artery Doppler characteristics and serum hormone levels in patients with Behçet disease.
abstract: OBJECTIVE
  The aim of the study was to examine serum hormone levels, ovarian volume, stromal artery Doppler parameters of patients with Behçet disease (BD) to assess whether there are vascular changes in the gonads of these patients.
  
  
  METHODS
  Twenty patients with BD and 31 healthy controls aged between 18-45 years were examined in the early follicular phase of the menstrual cycle (day 2-3) with transvaginal ultrasound to evaluate ovarian volume and ovarian stromal artery Doppler parameters. On the same day, blood was drawn for determining serum hormone levels.
  
  
  RESULTS
  Patients with BD and the controls were comparable with regard to age and body mass index at study inclusion. Although comparison of the ovarian stromal artery Doppler velocimetric parameters did not show significant differences, resistivity, pulsatility indexes and systolic/diastolic ratio were higher, while peak systolic and end diastolic velocities were lower, in BD patients compared to controls. The mean ovarian volume of patients with BD was smaller than the controls but this difference did not reach statistical significance. There were no statistically significant differences between serum hormone levels of either group. We did not find any correlations between hormone levels and mean ovarian stromal artery Doppler parameters of patients with BD.
  
  
  CONCLUSIONS
  Ovarian stromal artery Doppler parameters of patients with BD did not show any significant differences compared to healthy controls. Therefore, we conclude that ovarian stromal artery is not involved in patients with BD as assessed by transvaginal Doppler ultrasound and serum hormone levels do not differ from the levels of healthy controls.
authors.affiliation: Department of Obstetrics and Gynecology, Kırıkkale University School of Medicine, Kırıkkale, Turkey.
authors.forename: Aylin Pelin
authors.initials: AP
authors.lastname: Cil
authors.forename: Ayşe Anıl
authors.initials: AA
authors.lastname: Karabulut
authors.forename: Mukadder
authors.initials: M
authors.lastname: Koçak
mesh_terms: D000293:Adolescent; D000328:Adult; D001158:Arteries / Q000000981:diagnostic imaging*; D001528:Behcet Syndrome / Q000097:blood* / Q000473:pathology; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D009929:Organ Size; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000473:pathology; D010908:Pituitary Hormones, Anterior / Q000097:blood*; D011388:Prolactin / Q000097:blood; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D018608:Ultrasonography, Doppler / Q000379:methods*; D055815:Young Adult
chemical_list: D012739:Gonadal Steroid Hormones; D010908:Pituitary Hormones, Anterior; D013739:Testosterone; D004958:Estradiol; D019314:Dehydroepiandrosterone Sulfate; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin