title: [Severe tick-borne encephalomyelitis with lack of cerebrospinal fluid pleocytosis].
abstract: Tick borne encephalitis (TBE) is an important viral encephalitis in central and eastern Europe. Cerebrospinal fluid (CSF) pleocytosis has been described in all published patients so far. This may be due to selection bias, however, as CSF pleocytosis is often used as a case definition parameter. The frequency of TBE without CSF pleocytosis is unknown. We report two cases who developed severe TBE without CSF pleocytosis. A normal CSF cell count should therefore not discourage from the differential diagnosis of TBE and deter from serological testing in patients with a clinical constellation suggesting TBE.
authors.affiliation: Klinik für Neurologie der Universität Regensburg. peter.poeschl@medbo.de
authors.forename: P
authors.initials: P
authors.lastname: Pöschl
authors.forename: I
authors.initials: I
authors.lastname: Kleiter
authors.forename: S
authors.initials: S
authors.lastname: Grubwinkler
authors.forename: E
authors.initials: E
authors.lastname: Bumes
authors.forename: U
authors.initials: U
authors.lastname: Bogdahn
authors.forename: G
authors.initials: G
authors.lastname: Dobler
authors.forename: A
authors.initials: A
authors.lastname: Steinbrecher
mesh_terms: D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid; D002452:Cell Count; D003071:Cognition; D003937:Diagnosis, Differential; D004675:Encephalitis, Tick-Borne / Q000134:cerebrospinal fluid* / Q000523:psychology; D006801:Humans; D007958:Leukocyte Count; D007964:Leukocytosis / Q000134:cerebrospinal fluid*; D008297:Male
chemical_list: D000914:Antibodies, Viral