Rash, fever and proteinuria after amoxicillin in a SLE patient.
We report a case of severe type IV hypersensitivity reaction to amoxicillin, which occurred in a person with a 12-year history of SLE. The present case illustrates the wide differential diagnosis in a SLE patient who presents with an allergic drug reaction. The attribution of the presenting symptoms to the underlying SLE and/or to the drugs used to treat SLE and coexisting conditions is a major challenge.
Couto
M
M
Rheumatology Fellow at the Department of Rheumatology, Coimbra University Hospital, Portugal. maura_couto@yahoo.com
Duarte
C
C
Geraldes
A
A
Medeiros
Colleen
C
Inês
L
L
Malcata
A
A
D000328:Adult; D000658:Amoxicillin / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D005076:Exanthema / Q000139:chemically induced*; D005260:Female; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011507:Proteinuria / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D000658:Amoxicillin