Coinfection by human immunodeficiency virus, hepatitis B virus and hepatitis C virus in injecting drug users.
Detection of hepatitis B surface antigen (HBsAg), anti hepatitis C virus (HCV) antibody and anti human immunodeficiency virus (HIV) antibody was carried out in serum samples from 250 injecting drug users (IDUs) from a deaddiction centre, Shalom, in Churachanpur district, Manipur during the period of August-October, 2002. One hundred and forty-nine (59.6%) IDUs were positive for HIV antibody, 226 (90.4%) were positive for anti HCV antibody and 27 (10.8%) were positive for HBsAg. There was coinfection of HIV, hepatitis B virus (HBV) and HCV in 15 (6%) of the IDUs. The coinfection of HBV and HCV was found in 12 cases (4.8%) and coinfection of HIV and HCV was found in 131 cases (52.4%). HIV and HCV were the highest among the coinfection of IDUs. The IDUs were in sexually active age group with a risk of infection to their sexual partner.
Devi
Kh Sulochana
KhS
Department of Microbiology, Regional Institute of Medical Sciences, Imphal 795004.
Singh
Ng Brajachand
NB
Singh
H Lokhendro
HL
Singh
Y Manihar
YM
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D005260:Female; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000635:transmission; D016174:Hepacivirus / Q000276:immunology*; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000276:immunology*; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology / Q000635:transmission; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D012189:Retrospective Studies; D017678:Sex Distribution; D015819:Substance Abuse, Intravenous / Q000097:blood / Q000150:complications*; D055815:Young Adult
D015483:HIV Antibodies; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies