title: Membrane biogenesis: networking at the ER with atlastin.
abstract: The peripheral endoplasmic reticulum forms a dynamic network of interconnected membrane tubules. Although some determinants of this striking architecture are known, the mechanism underlying fusion of individual tubules has remained elusive. Two studies now identify atlastin proteins as key mediators of homotypic fusion of endoplasmic reticulum membranes.
authors.affiliation: Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland.
authors.forename: Hesso
authors.initials: H
authors.lastname: Farhan
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Hauri
mesh_terms: D004721:Endoplasmic Reticulum / Q000737:chemistry / Q000502:physiology*; D020558:GTP Phosphohydrolases / Q000378:metabolism*; D019204:GTP-Binding Proteins; D007425:Intracellular Membranes / Q000378:metabolism*; D008565:Membrane Proteins; D008958:Models, Molecular; D013045:Species Specificity
chemical_list: D008565:Membrane Proteins; C440006:ATL1 protein, human; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins