Dietary intake and urinary excretion of lignans in Finnish men.
Intake of lignans has been assessed in different study populations, but so far none of the studies has compared the daily intake of lignans and the urinary excretion of plant and enterolignans. We assessed the intake of lariciresinol, pinoresinol, secoisolariciresinol and matairesinol in 100 Finnish men consuming their habitual omnivorous diet, and measured the 24 h urinary excretion of plant and enterolignans to compare the intake and metabolism. Dietary determinants of lignan intake and their urinary excretion were also determined. The mean intake of lignans was 1224 (sd 539) mug/d, of which lariciresinol and pinoresinol covered 78 %. Almost half (47 %) of the intake of lignans was explained by the intake of rye products, berries, coffee, tea and roots. The urinary excretion of plant lignans corresponded to 17 % and enterolignans to 92 % of the intake of lignans. The urinary excretion of plant lignans was explained 14 % by the intake of rye products and intake of coffee, and consequently 3-7 % by the intake of water-insoluble fibre. The urinary excretion of enterolactone was explained 11 % by the intake of vegetables and rye products, 14 % by the intake of water-soluble fibre and only 4 % by the intake of lariciresinol. Although the assessed intake of lignans corresponded well with the urinary excretion of lignans, the enterolactone production in the human body depended more on the dietary sources of lignans than the absolute intake of lignans.
Nurmi
Tarja
T
Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, PO Box 1627, FI-70211 Kuopio, Finland. tarja.nurmi@uku.fi
Mursu
Jaakko
J
Peñalvo
José L
JL
Poulsen
Henrik E
HE
Voutilainen
Sari
S
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000652:urine; D003069:Coffee; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage; D005387:Finland; D005638:Fruit; D006801:Humans; D017705:Lignans / Q000008:administration & dosage* / Q000652:urine*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage* / Q000652:urine*; D018517:Plant Roots; D012434:Secale; D013662:Tea
D003069:Coffee; D004043:Dietary Fiber; D017705:Lignans; D010936:Plant Extracts; D013662:Tea; D015107:4-Butyrolactone; C029497:2,3-bis(3'-hydroxybenzyl)butyrolactone