title: [Methods of correcting hepatic arterial blood supply for subsequent implantation of the "port-catheter" infusion system].
abstract: The study was undertaken to investigate the feasibility of using surgical and roentgenoendovascular redistribution of the hepatic arterial blood flow for adequate implantation of the "port-catheter" infusion system. Between December 2001 and March 2008, we performed surgical (n = 25) or transcutaneous (n = 22) implantations of the infusion systems for carrying out regional chemotherapy in a total of forty-seven patients presenting with hepatic metastases of colorectal carcinoma. Anatomical variants of the hepatic arteries were observed in eleven cases. The blood stream was corrected by means of either transcatheter embolization (n = 7), ligation (n = 2), or transposition (n = 2) of the aberrant arteries. No complications were encountered. In all the cases, the "port-catheter" system was implanted successfully, with adequate hepatic perfusion achieved. Both transcatheter embolization and surgical reconstruction turned out to be efficient methods in correction of the blood flow in various anatomical structures of the hepatic arteries, thus favourably contributing to increased efficacy of regional chemotherapy.
authors.forename: M I
authors.initials: MI
authors.lastname: Generalov
authors.forename: P V
authors.initials: PV
authors.lastname: Balakhnin
authors.forename: I O
authors.initials: IO
authors.lastname: Rutkin
authors.forename: D N
authors.initials: DN
authors.lastname: Maĭstrenko
authors.forename: V A
authors.initials: VA
authors.lastname: Tsurkan
authors.forename: A A
authors.initials: AA
authors.lastname: Polikarpov
authors.forename: P G
authors.initials: PG
authors.lastname: Tarazov
authors.forename: D A
authors.initials: DA
authors.lastname: Granov
authors.forename: V N
authors.initials: VN
authors.lastname: Polysalov
authors.forename: O A
authors.initials: OA
authors.lastname: Krotova
mesh_terms: D000368:Aged; D000792:Angiography; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols; D002408:Catheters, Indwelling; D016461:Chemoembolization, Therapeutic; D003097:Collateral Circulation; D015179:Colorectal Neoplasms; D003287:Contrast Media / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006499:Hepatic Artery / Q000002:abnormalities / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000706:statistics & numerical data*; D007459:Iodized Oil / Q000008:administration & dosage; D008026:Ligation; D008099:Liver / Q000098:blood supply*; D008102:Liver Circulation; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon; D036542:Tomography, Spiral Computed; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D003287:Contrast Media; D007459:Iodized Oil; D004317:Doxorubicin