title: New genotype of dengue type 3 virus circulating in Brazil and Colombia showed a close relationship to old Asian viruses.
abstract: Dengue type 3 genotype V viruses have been recently detected in Brazil and Colombia. In this study, we described another Brazilian isolate belonging to this genotype. Phylogenetic analysis including dengue type 3 viruses isolated worldwide showed that Brazilian and Colombian viruses were closely related to viruses isolated in Asia more than two decades ago. The characteristic evolutionary pattern of dengue type 3 virus cannot explain the close similarity of new circulating viruses with old viruses. Further studies are needed to confirm the origin of the new dengue type III genotype circulating in Brazil and Colombia.
authors.affiliation: Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brasil. vhugo@fcfrp.usp.br
authors.forename: Victor Hugo
authors.initials: VH
authors.lastname: Aquino
authors.forename: Alberto Anastacio
authors.initials: AA
authors.lastname: Amarilla
authors.forename: Helda Liz
authors.initials: HL
authors.lastname: Alfonso
authors.forename: Weber Cheli
authors.initials: WC
authors.lastname: Batista
authors.forename: Luiz Tadeu Moraes
authors.initials: LT
authors.lastname: Figueiredo
mesh_terms: D020413:3' Untranslated Regions; D001938:Brazil; D003105:Colombia; D003715:Dengue / Q000097:blood / Q000821:virology*; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics*; D019143:Evolution, Molecular; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D014759:Viral Envelope Proteins / Q000235:genetics; D017361:Viral Nonstructural Proteins / Q000235:genetics; D014780:Viruses / Q000235:genetics*
chemical_list: D020413:3' Untranslated Regions; C084188:E protein, Dengue virus type 3; C546113:NS1 protein, Dengue virus type 3; D012367:RNA, Viral; D014759:Viral Envelope Proteins; D017361:Viral Nonstructural Proteins