Persistent intermediate uveitis associated with latent manifestation of facial large B-cell non-Hodgkin lymphoma.
OBJECTIVE
To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy.


METHODS
Retrospective, interventional case report.


METHODS
A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive.


RESULTS
Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity.


CONCLUSIONS
NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.
Sabet-Peyman
E Jason
EJ
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Eberhart
Charles G
CG
Janjua
Kashif
K
Shah
Syed Mahmood
SM
Do
Diana V
DV
Nguyen
Quan Dong
QD
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005153:Facial Neoplasms / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000150:complications* / Q000188:drug therapy; D012189:Retrospective Studies; D016896:Treatment Outcome; D015867:Uveitis, Intermediate / Q000209:etiology*