[Somatostatin receptor scintigraphy in pediatric bronchial carcinoid tumor].
BACKGROUND
Carcinoid tumor is a rare neuroendocrine neoplasm with different locations, the most frequent ones during the pediatric age being the appendix and lung. Scintigraphy with (111)In-DTPA-d-Phe(1)-octreotide has led to an importance advance in the diagnosis of extension in carcinoid tumor patients. We present three pediatric patients with bronchial carcinoid studied with somatostatin analogue scintigraphy (SSRS).


METHODS
The first patient (9 years) was studied using the SSRS after surgery due to carcinoid tumor in the right lower lobe in which tumor remains was observed (this being clearer in the tomography study). The second patient (10 years) presented due to endobronchial tumor in the left lower lobe together with atelectasis of the LUL and emphysema of the LLL. Radiology imaging techniques suggested the differential diagnosis between the endobronchial carcinoid tumor or plasma cells or foreign body gramuloma. The SSRS showed an abnormal deposit of activity in the left hemithorax consisted with carcinoid tumor. No other areas suggesting metastasis were observed. After the surgery (endobronchial resection), new controls with SSRS showed absence of disease. The third patient (12 years) came after a lobectomy (RUL) due to bronchial carcinoid. The SSRS did not show any abnormal areas of activity. In the subsequent control (3 months), a deposit of activity was observed in the middle third of the right hemithorax, after which a lobectomy was performed (RLL and ML) that showed small remains of neuroendocrine carcinoid. Subsequent controls were negative.


CONCLUSIONS
The SSRS has demonstrated great utility in the diagnosis, follow-up and staging of pediatric patients, carriers of neuroendocrine carcinoid tumors.
Hervás Benito
I
I
Hospital Universitario La Fe, Valencia, España. hervas_isaben@gva.es
Bello Arques
P
P
Loaiza
J L
JL
Vercher
J L
JL
Velasco
R P
RP
Rivas Sánchez
A
A
Ruiz Llorca
C
C
Martí Vidal
J F
JF
Mateo Navarro
A
A
D014408:Biomarkers, Tumor / Q000032:analysis*; D001984:Bronchial Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000601:surgery; D002276:Carcinoid Tumor / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000601:surgery; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008175:Lung Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis*; D015282:Octreotide / Q000031:analogs & derivatives; D011013:Pneumonectomy; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D001261:Pulmonary Atelectasis / Q000209:etiology; D011656:Pulmonary Emphysema / Q000209:etiology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin / Q000032:analysis*; D012086:Reoperation
D014408:Biomarkers, Tumor; D007205:Indium Radioisotopes; D009363:Neoplasm Proteins; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; C094279:indium-111-octreotide; D015282:Octreotide