title: Methods of design, simulation, and control for the development of new VAD/TAH concepts.
abstract: Cardiovascular diseases are a major cause of death worldwide. If medical treatments fail to restore adequate blood flow in a patient, mechanical support is needed. To date, many different types of blood pumps have been developed, but only few are clinically available. This review article describes the challenges involved in this field of research and gives an overview of the development process. Past developments as well as current and new technologies and approaches applied are summarized. Finally, a perspective for improved devices is discussed.
authors.affiliation: Department of Applied Medical Engineering, RWTH Aachen, Aachen, Germany. finocchiaro@hia.rwth-aachen.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Finocchiaro
authors.forename: Stefanie
authors.initials: S
authors.lastname: Heinke
authors.forename: Mehdi
authors.initials: M
authors.lastname: Behbahani
authors.forename: Marc
authors.initials: M
authors.lastname: Lessmann
authors.forename: Marco
authors.initials: M
authors.lastname: Laumen
authors.forename: Ulrich
authors.initials: U
authors.lastname: Steinseifer
authors.forename: Thomas
authors.initials: T
authors.lastname: Schmitz-Rode
authors.forename: Steffen
authors.initials: S
authors.lastname: Leonhardt
authors.forename: Marek
authors.initials: M
authors.lastname: Behr
authors.forename: Kay
authors.initials: K
authors.lastname: Hameyer
mesh_terms: D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design / Q000379:methods*; D019544:Equipment Failure Analysis / Q000379:methods; D005246:Feedback; D006354:Heart, Artificial; D006801:Humans; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity