title: Anesthetic management of acute mesenteric ischemia in elderly patients.
abstract: Ischemic insult to the splanchnic vasculature can jeopardize bowel viability and lead to devastating consequences, including bowel necrosis and gangrene. Although acute mesenteric ischemia (AMI) may occur at any age, the elderly are most commonly affected due to their higher incidence of underlying systemic pathology, most notably atherosclerotic cardiovascular disease. Treatment options include pharmacology-based actions, endovascular, and surgical interventions. AMI remains a life-threatening condition with a mortality rate of 60% to 80%, especially if intestinal infarction has occurred and surgical intervention becomes emergent. Early recognition and an aggressive therapeutic approach are essential if the usually poor outcome is to be improved. Anesthetic management is complex and must account for comorbid disease as well as the patient's presumptive acute deterioration. Blood pressure support typically involves careful, but often massive, fluid resuscitation and may also additionally require pharmacologic support.
authors.affiliation: Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195-6540, USA. vitin@u.washington.edu
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Vitin
authors.forename: Julia I
authors.initials: JI
authors.lastname: Metzner
mesh_terms: D000208:Acute Disease; D000368:Aged; D000758:Anesthesia; D005440:Fluid Therapy; D006801:Humans; D007511:Ischemia / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery / Q000628:therapy*; D008297:Male; D011183:Postoperative Complications / Q000628:therapy; D011300:Preoperative Care; D012151:Resuscitation; D013152:Splanchnic Circulation; D017131:Thrombectomy