Alpha,gamma-cyclic peptide ensembles with a hydroxylated cavity.
Here we describe a self-assembling alpha,gamma-cyclic tetrapeptide that contains the 4-amino-3-hydroxytetrahydrofuran-2-carboxylic acid, in which the hydroxy group is pointing towards the inner cavity of the resulting dimers.
Reiriz
César
C
Departamento de Química Orgánica, Laboratorios del CSIC, Facultad de Química, Universidad de Santiago, 15782, Santiago de Compostela, Spain.
Amorín
Manuel
M
García-Fandiño
Rebeca
R
Castedo
Luis
L
Granja
Juan R
JR
D000596:Amino Acids / Q000737:chemistry; D019281:Dimerization; D006900:Hydroxylation; D007536:Isomerism; D008958:Models, Molecular; D008968:Molecular Conformation; D010456:Peptides, Cyclic / Q000737:chemistry*
D000596:Amino Acids; D010456:Peptides, Cyclic