Bipolar affective disorder associated with thenar hypoplasia: is lithium safe?
Thenar hypoplasia has been described to occur as a part of radial longitudinal deficiency syndromes and occasionally related to Holt-Oram syndrome in which both cardiac and skeletal abnormalities co-occur. We describe a case with bilateral thenar hypoplasia, which resembles a milder variety of Holt-Oram syndrome, who developed bradycardia after exposure to lithium at therapeutic doses.
Praharaj
Samir Kumar
SK
Department of Psychiatry, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. samirpsyche@yahoo.co.in
Siddiqui
Aleem
A
Sinha
Vinod Kumar
VK
D000328:Adult; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D001919:Bradycardia / Q000139:chemically induced*; D006228:Hand Deformities, Congenital / Q000150:complications; D006801:Humans; D018020:Lithium Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D013577:Syndrome
D018020:Lithium Compounds