[Genetic polymorphisms of six X-short tandem repeats loci in Chinese Korean].
OBJECTIVE
To investigate the genetic polymorphisms of DXS7132, DXS6854, DXS6797, DXS9898, DXS8378 and GATA31E08 short tandem repeats (STRs) loci in Chinese Korean ethnic group of Yanbian, Jilin, and to construct a preliminary database.


METHODS
The allele frequencies of the six STRs loci in Chinese Korean ethnic individuals were analyzed by multiplex polymerase chain reaction (PCR) and polyacrylamide gel electrophoresis (PAGE).


RESULTS
Total of 8, 6, 8, 8, 5 and 10 alleles were observed in each locus respectively. All loci (in female) met Hardy-Weinberg equilibrium (P > 0.05). The statistical analysis of the 6 STR loci showed the heterozygosities were more than 0.4660, the polymorphic information contents (PIC) were more than 0.5293, the haplotype diversity were more than 0.9993, power of discrimination (PD) in females and males were more than 0.7737 and 0.6107, respectively.


CONCLUSIONS
The results showed that, all the 6 STR loci in this study were found to have high heterozygosity and polymorphic information content, so they could provide useful markers for genetic purposes. These results could serve as valuable data to enrich the Chinese Korean ethnic group genetic database and play an important role in genetic study of Chinese population.
Zhang
Yong-ji
YJ
Department of Forensic Medicine, Yanbian University College of Medicine, Yanji, Jilin, 133000, PR China.
Li
Zhe
Z
Xu
Jing-nan
JN
Zhang
Mei-hua
MH
Han
Song-ying
SY
D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D005260:Female; D006801:Humans; D007723:Korea; D008297:Male; D018895:Microsatellite Repeats; D011110:Polymorphism, Genetic