[Management of serum calcium with cinacelet in parathyroid cancer].
Treatment with cinacalcet and intravenous bisphosphonate has improved the previously often fatal prognosis of parathyroid cancer. We report two cases, of which one did not react to treatment and died within a short time-frame. In the other case, cinacalcet controlled serum calcium during a prolonged time period despite metastases. However, increasing doses of cinacalcet combined with more frequent intravenous bisphosphonate were necessary.
Vestergaard
Peter
P
Medicinsk Afdeling C, Arhus Universitetshospital, Arhus Sygehus, DK-8000 Arhus C. p-vest@post4.tele.dk
Sanden
Anne Katrine
AK
D000368:Aged; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002118:Calcium / Q000097:blood*; D000069449:Cinacalcet; D004164:Diphosphonates / Q000008:administration & dosage / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use*; D010282:Parathyroid Neoplasms / Q000097:blood / Q000188:drug therapy*; D011379:Prognosis; D016896:Treatment Outcome; D000077211:Zoledronic Acid
D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D009281:Naphthalenes; D000077211:Zoledronic Acid; D002118:Calcium; D000069449:Cinacalcet