title: N-heterocyclic carbene-catalyzed hydroacylation of unactivated double bonds.
abstract: An intramolecular N-heterocyclic carbene (NHC)-catalyzed hydroacylation of unactivated double bonds is reported. Systematic variation of the catalyst structure revealed an N-mesitylthiazolylidene annulated with a seven-membered ring to be especially reactive. This NHC enables a unique C-C bond-forming reaction to afford substituted chroman-4-ones in moderate to excellent yields, even ones containing all-carbon quaternary centers.
authors.affiliation: Organisch-Chemisches Institut der Westfälischen Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hirano
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju
authors.forename: Isabel
authors.initials: I
authors.lastname: Piel
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius