title: Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide.
abstract: Covalently cross-linked homodimeric Abeta peptides have been prepared by solid-phase peptide synthesis by exploiting 'site-site interactions', and exhibit substantially increased oligomerisation and fibrillisation properties compared with the corresponding monomers.
authors.affiliation: School of Chemistry, The University of Melbourne, Parkville, VIC 3010, Australia.
authors.forename: W Mei
authors.initials: WM
authors.lastname: Kok
authors.forename: Denis B
authors.initials: DB
authors.lastname: Scanlon
authors.forename: John A
authors.initials: JA
authors.lastname: Karas
authors.forename: Luke A
authors.initials: LA
authors.lastname: Miles
authors.forename: Deborah J
authors.initials: DJ
authors.lastname: Tew
authors.forename: Michael W
authors.initials: MW
authors.lastname: Parker
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Barnham
authors.forename: Craig A
authors.initials: CA
authors.lastname: Hutton
mesh_terms: D000595:Amino Acid Sequence; D016229:Amyloid beta-Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D003432:Cross-Linking Reagents; D008969:Molecular Sequence Data; D055503:Protein Multimerization
chemical_list: D016229:Amyloid beta-Peptides; D003432:Cross-Linking Reagents