Silver(I)-catalyzed dual activation of propargylic alcohol and aziridine/azetidine: triggering ring-opening and endo-selective ring-closing in a cascade.
[Ag(COD)(2)]PF(6) catalyzes the reaction between propargyl alcohols and N-tosylaziridines/azetidines leading to a diverse range of N,O-heterocycles, namely, oxazines, oxazepines, and oxazocines via ring-opening and ring-closing in a cascade.
Bera
Milan
M
Organometallics & Catalysis Laboratory, Chemistry Department, Indian Institute of Technology, Kharagpur 721302, India.
Roy
Sujit
S
D000480:Alkynes / Q000737:chemistry*; D001384:Azetidines / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010077:Oxazepines / Q000138:chemical synthesis / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D001384:Azetidines; D001388:Aziridines; D009942:Organometallic Compounds; D010077:Oxazepines; D020005:Propanols; C082735:azetidine; D012834:Silver; C033132:aziridine; C028255:propargyl alcohol