title: A longitudinal investigation of the impact of typology of urinary incontinence on quality of life during midlife: results from a British prospective study.
abstract: Using prospective data from 983 British women born in 1946, the study aims to describe the profiles of symptoms of stress, urge, and severe incontinence, and to relate these to change in quality of life. Based on the longitudinal patterns of symptoms experienced, four groups of women were defined: 'low symptom', 'onset', 'recovering', and 'chronic'. Childhood enuresis was associated with being in the 'chronic' group for urge and severe incontinence. Women in the 'recovering' group for stress incontinence experienced an improvement in the physical health domain (regression coefficient (95% CI): 0.1(0.02, 0.18)) compared with women without symptoms. This relationship existed beyond the effects of ageing, menopausal status, current life stress, and reproductive, lifestyle, and social factors. More research is needed to understand the mechanism that link childhood enuresis to being in the 'chronic' group for urge and severe incontinence.
authors.affiliation: MRC unit for Lifelong Health and Ageing, University College and Royal Free Medical School, 33 Bedford Place, London WC1B5JU, United Kingdom. g.mishra@nshd.mrc.ac.uk
authors.forename: Gita D
authors.initials: GD
authors.lastname: Mishra
authors.forename: Tim
authors.initials: T
authors.lastname: Croudace
authors.forename: Linda
authors.initials: L
authors.lastname: Cardozo
authors.forename: Diana
authors.initials: D
authors.lastname: Kuh
mesh_terms: D002648:Child; D002908:Chronic Disease; D005260:Female; D006304:Health Status; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D006113:United Kingdom; D014549:Urinary Incontinence / Q000145:classification*