[First episode of psychosis intensive early intervention programme versus standard treatment--secondary publication].
A total of 547 patients with a first episode of psychosis were randomised to two years of intensive early intervention programme (OPUS) versus standard treatment. OPUS treatment consisted of Assertive Community Treatment (ACT) with manuals for family involvement and social skills training. Standard treatment comprised contact with a community mental health centre. OPUS treatment improved the clinical outcome after two years of treatment, but the effects were not sustainable up to five years after. The secondary outcome measures showed a difference on supported housing and use of bed-days at the five-year follow-up in favour of OPUS treatment.
Bertelsen
Mette
M
Bispebjerg, Psykiatrisk Center Sct Hans, og Arhus Universitetshospital, Risskov.
Jeppesen
Pia
P
Petersen
Lone
L
Thorup
Anne
A
Øhlenschlaeger
Johan
J
le Quach
Phuong
P
Christensen
Torben Østergaard
TØ
Krarup
Gertrud
G
Jørgensen
Per
P
Nordentoft
Merete
M
D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001242:Assertiveness; D003155:Community Mental Health Centers; D003156:Community Mental Health Services; D005196:Family Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D012008:Recurrence; D012951:Socialization; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
D014150:Antipsychotic Agents