[Leukoplakia and erythroplakia--two orale precursor lesions].
The oral leukoplakia/erythroplakia is one of the most common epithelial precursor lesions of the oral squamous cell carcinoma. A clinical distinction is drawn between homogeneous and non-homogeneous as well as proliferative verrucous leukoplakia and erythroplakia. Due to the fact that the oral squamous cell carcinoma has a poor prognosis it is very important to decrease morbidity and mortality by systematic primary, secondary and tertiary prevention of the oral leukoplakia/erythroplakia. On the basis of histological classification systems the risk of malignant transformation can be evaluated, a defined therapy can be induced and the prognosis can be derived.
Grajewski
S
S
Institut für Arbeitsmedizin, Berlin. sonja.grajewski@charite.de
Groneberg
D
D
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D004919:Erythroplasia / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D006801:Humans; D017733:Leukoplakia, Hairy / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000517:prevention & control; D007972:Leukoplakia, Oral / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D011230:Precancerous Conditions / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D011379:Prognosis; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects