title: Dynamic patterns in a supported lipid bilayer driven by standing surface acoustic waves.
abstract: In the past decades supported lipid bilayers (SLBs) have been an important tool in order to study the physical properties of biological membranes and cells. So far, controlled manipulation of SLBs is very limited. Here we present a new technology to create lateral patterns in lipid membranes controllable in both space and time. Surface acoustic waves (SAWs) are used to generate lateral standing waves on a piezoelectric substrate which create local "traps" in the lipid bilayer and lead to a lateral modulation in lipid concentration. We demonstrate that pattern formation is reversible and does not affect the integrity of the lipid bilayer as shown by extracting the diffusion constant of fluid membranes. The described method could possibly be used to design switchable interfaces for the lateral transport and organization of membrane bound macromolecules to create dynamic bioarrays and control biofilm formation.
authors.affiliation: Center for Nanoscience, CeNS, Ludwig-Maximilians-Universität, Fakultät für Physik, Geschwister Scholl Platz 1, D-80539 München, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Hennig
authors.forename: Jürgen
authors.initials: J
authors.lastname: Neumann
authors.forename: Achim
authors.initials: A
authors.lastname: Wixforth
authors.forename: Joachim O
authors.initials: JO
authors.lastname: Rädler
authors.forename: Matthias F
authors.initials: MF
authors.lastname: Schneider
mesh_terms: D000162:Acoustics; D004867:Equipment Design; D056656:Lab-On-A-Chip Devices; D008051:Lipid Bilayers / Q000737:chemistry*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D008856:Microscopy, Fluorescence; D008962:Models, Theoretical
chemical_list: D008051:Lipid Bilayers