title: Alcohol consumption and development of acute respiratory distress syndrome: a population-based study.
abstract: This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA. lokendrat2001@yahoo.com
authors.forename: Lokendra
authors.initials: L
authors.lastname: Thakur
authors.forename: Marija
authors.initials: M
authors.lastname: Kojicic
authors.forename: Sweta J
authors.initials: SJ
authors.lastname: Thakur
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Pieper
authors.forename: Rahul
authors.initials: R
authors.lastname: Kashyap
authors.forename: Cesar A
authors.initials: CA
authors.lastname: Trillo-Alvarez
authors.forename: Fernandez
authors.initials: F
authors.lastname: Javier
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Cartin-Ceba
authors.forename: Ognjen
authors.initials: O
authors.lastname: Gajic
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000503:physiopathology*; D012189:Retrospective Studies