Khaini chewing damages chromosomes 2q, 3p and 21q: occurrence in a South Asian population.
Chewing Khaini damages chromosomes, in the form of loss of heterozygosity (LOH), identified on the long arm of chromosome 2 (2q), the short arm of chromosome 3 (3p) and the long arm of chromosome 21 (21q) of oral cancer cases who had quid chewing habit of more than 10 years duration, and chewed 10-15 times a day.
Choudhury
Chitta R
CR
International Centre for Tropical Oral Health, Poole Hospital NHS and Bournemouth University, England.
Chowdhury
Avidyuti
A
Prasad
Rajendra B
RB
Shibahara
Takahiko
T
D001208:Asia; D002869:Chromosome Aberrations / Q000187:drug effects*; D002889:Chromosomes, Human, Pair 2; D002891:Chromosomes, Human, Pair 21; D002893:Chromosomes, Human, Pair 3; D006801:Humans; D019656:Loss of Heterozygosity / Q000187:drug effects*; D014030:Tobacco, Smokeless / Q000009:adverse effects*