title: Orofacial dystonia triggered by mouth closure.
abstract: Focal task-specific dystonia affects one part of the body, occurring only during the performance of a specific task. It usually affects the hand, though it can rarely affect the orofacial region. Treatment with oral medications and botulinum toxin (BTX) usually produces only modest benefit, owing to the complexity of the movements involved. We describe a patient with an unusual form of focal task-specific orofacial dystonia, manifested by asynchronous twitching of the right and left lower hemiface upon closure of the mouth and pursing of the lips. Injection of BTX produced complete resolution of task-specific dystonia for 4.5 months.
authors.affiliation: National University Health System, National University of Singapore, Singapore.
authors.forename: Chong-Han
authors.initials: CH
authors.lastname: Pek
authors.forename: Raymond C S
authors.initials: RC
authors.lastname: Seet
authors.forename: Jing-Hui
authors.initials: JH
authors.lastname: Yik
authors.forename: Erle C H
authors.initials: EC
authors.lastname: Lim
mesh_terms: D001905:Botulinum Toxins / Q000627:therapeutic use; D004421:Dystonia / Q000209:etiology*; D005158:Facial Paralysis / Q000209:etiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009055:Mouth / Q000502:physiology*; D009069:Movement Disorders / Q000209:etiology*; D013035:Spasm / Q000150:complications
chemical_list: D001905:Botulinum Toxins