title: Intra-hepatic splenosis as an unexpected cause of a focal liver lesion in a patient with hepatitis C and liver cirrhosis: a case report.
abstract: BACKGROUND
  Splenosis is the heterotopic autotransplantation of splenic tissue, mostly found after splenic trauma or surgery in the abdominal, pelvic or thoracic cavity. Here we report a patient with a history of splenectomy after polytrauma with chronic hepatitis C and liver cirrhosis presenting with an hepatic mass of unknown origin.
  
  
  METHODS
  The lesion could not be exactly classified by ultrasound, computed tomography, angiography and biopsy, classical features of malignancy were not fulfilled, and on the other hand a neoplastic process could neither be excluded. After revision of a MRI performed in our centre it appeared that the liver mass contrasted in the same way as the remaining accessory spleens in the left upper quadrant. A selective Tc-99m-labelled heat-denatured autologous red blood cells scintigraphy of the spleen was performed and showed both the accessory spleens in the left upper quadrant and spleen-typical tissue in projection to the left liver lobe and confirmed the diagnosis of splenosis.
  
  
  CONCLUSIONS
  Although intrahepatic splenosis represents an extremely rare condition, this diagnosis should always be taken into consideration in patients with history of abdominal trauma with splenic involvement presenting with an indeterminate focal liver lesion. The diagnosis of splenosis may then be reliably confirmed by Tc-99m-DRBC scintigraphy.
authors.affiliation: Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Marianne
authors.initials: M
authors.lastname: Menth
authors.affiliation: Institute of Clinical Radiology, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Karin
authors.initials: K
authors.lastname: Herrmann
authors.affiliation: Department of Nuclear Medicine, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Haug
authors.affiliation: Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Bijan
authors.initials: B
authors.lastname: Raziorrouh
authors.affiliation: Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Reinhart
authors.initials: R
authors.lastname: Zachoval
authors.affiliation: Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Christina-Maria
authors.initials: CM
authors.lastname: Jung
authors.affiliation: Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Otto