[Risk factors for non-response in inpatient depression treatment].
OBJECTIVE
The aim of this study was to identify predictors of non-response in inpatient depression treatment by means of routinely collected data from 10 psychiatric clinics.


METHODS
Evaluation was carried out through univariate analyses first; subsequently a model was developed by means of multivariate analyses.


RESULTS
About one third (31.5 %) of the 511 patients included in the study was classified as non-responder. Concerning patient level, psychic comorbidity, severity of depression symptoms and serious impairment of lifestyle as indication for hospitalisation have an impact on treatment outcome. In contrast, socio-demographic characteristics are not suitable as predictors. On the level of process characteristics, psychotherapy and patient compliance to medication enhanced the chance of profiting from inpatient treatment.


CONCLUSIONS
The results can be integrated into a well interpretable model of the current inpatient depression treatment. Non-response is not yet sufficiently predictable through routine data.
Hölzel
Lars
L
Universitätsklinikum Freiburg, Abteilung für Psychiatrie und Psychotherapie, Sektion Klinische Epidemiologie und Versorgungsforschung.
Wolff
Alessa von
Av
Kriston
Levente
L
Härter
Martin
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010043:Outcome and Process Assessment, Health Care / Q000706:statistics & numerical data; D010343:Patient Admission; D010349:Patient Compliance; D010555:Personality Inventory; D011613:Psychotherapy; D012008:Recurrence; D017211:Treatment Failure; D055815:Young Adult
D000928:Antidepressive Agents