Dendrite formation of cerebellar Purkinje cells.
During postnatal cerebellar development, Purkinje cells form the most elaborate dendritic trees among neurons in the brain, which have been of great interest to many investigators. This article overviews various examples of cellular and molecular mechanisms of formation of Purkinje cell dendrites as well as the methodological aspects of investigating those mechanisms.
Tanaka
Masahiko
M
Department of Cellular Biophysics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan. mtanaka@phar.nagoya-cu.ac.jp
D000818:Animals; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2 / Q000502:physiology; D002352:Carrier Proteins / Q000502:physiology; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000254:growth & development*; D003712:Dendrites / Q000502:physiology*; D005822:Genetic Vectors; D000072233:Homer Scaffolding Proteins; D006801:Humans; D009419:Nerve Tissue Proteins; D011401:Promoter Regions, Genetic / Q000502:physiology; D011689:Purkinje Cells / Q000502:physiology*
D002352:Carrier Proteins; D000072233:Homer Scaffolding Proteins; D009419:Nerve Tissue Proteins; C091104:Purkinje cell protein L7; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2