title: Ultrastable iron oxide nanoparticle colloidal suspensions using dispersants with catechol-derived anchor groups.
abstract: We have found catechol-derivative anchor groups which possess irreversible binding affinity to iron oxide and thus can optimally disperse superparamagnetic nanoparticles under physiologic conditions. This not only leads to ultrastable iron oxide nanoparticles but also allows close control over the hydrodynamic diameter and interfacial chemistry. The latter is a crucial breakthrough to assemble functionalized magnetic nanoparticles, e.g., as targeted magnetic resonance contrast agents.
authors.affiliation: Laboratory of Surface Science and Technology, ETH Zurich, Switzerland.
authors.forename: Esther
authors.initials: E
authors.lastname: Amstad
authors.forename: Torben
authors.initials: T
authors.lastname: Gillich
authors.forename: Idalia
authors.initials: I
authors.lastname: Bilecka
authors.forename: Marcus
authors.initials: M
authors.lastname: Textor
authors.forename: Erik
authors.initials: E
authors.lastname: Reimhult
mesh_terms: D002396:Catechols / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D007501:Iron / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008280:Magnetics; D008422:Materials Testing; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D013499:Surface Properties; D013535:Suspensions / Q000737:chemistry
chemical_list: D002396:Catechols; D046911:Macromolecular Substances; D013535:Suspensions; D007501:Iron; C034221:catechol