Adrenocortical cancer.
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy causing up to 0.2% of all cancer deaths This article reviews the incidence, presentation, and pathology of ACC. Particular attention is paid to the molecular oncogenesis of this disease, and the surgical and therapeutic options available for its cure.
Wandoloski
Melissa
M
Translational Genomics Research Institute, Clinical Translational Research Division, Phoenix, AZ 85004, USA.
Bussey
Kimberly J
KJ
Demeure
Michael J
MJ
D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D020022:Genetic Predisposition to Disease; D006801:Humans; D008939:Mitotane / Q000627:therapeutic use
D018931:Antineoplastic Agents, Hormonal; D008939:Mitotane