Alcohol consumption and development of acute respiratory distress syndrome: a population-based study.
This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
Thakur
Lokendra
L
Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA. lokendrat2001@yahoo.com
Kojicic
Marija
M
Thakur
Sweta J
SJ
Pieper
Matthew S
MS
Kashyap
Rahul
R
Trillo-Alvarez
Cesar A
CA
Javier
Fernandez
F
Cartin-Ceba
Rodrigo
R
Gajic
Ognjen
O
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000503:physiopathology*; D012189:Retrospective Studies