title: Three-dimensional flow characteristics in aortic coarctation and poststenotic dilatation.
abstract: The authors present findings from a scientific study in a 36-year-old male patient who was transferred for the evaluation of a restenosis in aortic coarctation that was initially treated by surgical repair. Contrast-enhanced magnetic resonance angiography and comprehensive flow-sensitive 4-dimensional magnetic resonance imaging for the evaluation of 3-dimensional blood flow in the entire thoracic aorta demonstrated distinct flow pattern changes associated with the disease, demonstrating a potential link between altered vascular hemodynamics and the development of vascular disease.
authors.affiliation: Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Albert-Ludwigs, University Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany. michael.markl@uniklinik-freiburg.de
authors.forename: Michael
authors.initials: M
authors.lastname: Markl
authors.forename: Raoul
authors.initials: R
authors.lastname: Arnold
authors.forename: Daniel
authors.initials: D
authors.lastname: Hirtler
authors.forename: Constantin
authors.initials: C
authors.lastname: von Zur Muhlen
authors.forename: Andreas
authors.initials: A
authors.lastname: Harloff
authors.forename: Mathias
authors.initials: M
authors.lastname: Langer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hennig
authors.forename: Alex
authors.initials: A
authors.lastname: Frydrychowicz
mesh_terms: D000328:Adult; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D001017:Aortic Coarctation / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D001783:Blood Flow Velocity; D004108:Dilatation, Pathologic / Q000175:diagnosis / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D011859:Radiography; D012008:Recurrence; D012039:Regional Blood Flow