title: Ultrasound-assisted one-pot, three-component synthesis of spiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2,6'(1'H)-diones in water.
abstract: A simple, facile, efficient and three-component procedure for the synthesis of spiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2,6'(1'H)-diones by the reaction of 4-hydroxycumarin, isatins and 1H-pyrazol-5-amines in water under ultrasonic irradiation is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of water as a solvent that is considered to be relatively environmentally benign.
authors.affiliation: Department of Chemistry, Shahid Beheshti University G.C., Tehran, Iran. a_bazgir@sbu.ac.ir
authors.forename: Ayoob
authors.initials: A
authors.lastname: Bazgir
authors.forename: Somayeh
authors.initials: S
authors.lastname: Ahadi
authors.forename: Ramin
authors.initials: R
authors.lastname: Ghahremanzadeh
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Khavasi
authors.forename: Peiman
authors.initials: P
authors.lastname: Mirzaei
mesh_terms: D015110:4-Hydroxycoumarins / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D055772:Green Chemistry Technology; D007211:Indoles / Q000737:chemistry; D007510:Isatin / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D011720:Pyrazoles / Q000737:chemistry; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D014465:Ultrasonics; D014867:Water / Q000737:chemistry*
chemical_list: D015110:4-Hydroxycoumarins; D007211:Indoles; D011720:Pyrazoles; D011728:Pyridones; D013141:Spiro Compounds; D014867:Water; D007510:Isatin; C068805:4-hydroxycoumarin