title: Genotypes, superantigen gene profiles, and presence of exfoliative toxin genes in clinical methicillin-susceptible Staphylococcus aureus isolates.
abstract: We compared genotype and virulence gene profiles for strains from carriers with autologous invasive infection (n = 56), nasal isolates from matched carriers (n = 108), and invasive strains from noncarriers (n = 34). Superantigen gene profiles and presence of exfoliative toxin genes A and D were associated with clonal complex rather than with invasive disease.
authors.affiliation: Maasstad Hospital, HT Rotterdam, The Netherlands. m.vantrijp@erasmusmc.nl
authors.forename: Marijke J C A
authors.initials: MJ
authors.lastname: van Trijp
authors.forename: Damian C
authors.initials: DC
authors.lastname: Melles
authors.forename: Susan V
authors.initials: SV
authors.lastname: Snijders
authors.forename: Heiman F L
authors.initials: HF
authors.lastname: Wertheim
authors.forename: Henri A
authors.initials: HA
authors.lastname: Verbrugh
authors.forename: Alex
authors.initials: A
authors.lastname: van Belkum
authors.forename: Willem J
authors.initials: WJ
authors.lastname: van Wamel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D002353:Carrier State / Q000382:microbiology; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D005083:Exfoliatins / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification; D018089:Superantigens / Q000235:genetics*; D037521:Virulence Factors / Q000235:genetics
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D005083:Exfoliatins; D018089:Superantigens; D037521:Virulence Factors