Stem cell transplantation for type 1 diabetes mellitus.
BACKGROUND
The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide beta cell regeneration.


CONCLUSIONS
High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus.
Voltarelli
Júlio C
JC
Department of Clinical Medicine, Ribeirão Preto School of Medicine, University of São Paulo, Brazil. jcvoltar@fmrp.usp.br.
Couri
Carlos Eduardo Barra
CE