title: Sirolimus-eluting stent placement for refractory renal artery in-stent restenosis: sustained patency and clinical benefit at 24 months.
abstract: Renal artery stenosis may cause or exacerbate hypertension and renal failure. Percutaneous transluminal renal artery stent placement, increasingly the first-line therapy for ostial atherosclerotic renal artery stenosis, can be complicated by in-stent restenosis weeks to months after the procedure. There is currently no consensus for the treatment of in-stent restenosis. Sirolimus-eluting stents have been shown to be effective to treat in-stent restenosis in the coronary circulation. We report a case of sustained 24-month patency after repair of recurrent renal artery in-stent restenosis with use of a sirolimus-eluting stent.
authors.affiliation: Division of Interventional Radiology, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029, USA. robert.lookstein@msnyuhealth.org
authors.forename: Robert A
authors.initials: RA
authors.lastname: Lookstein
authors.forename: Adam D
authors.initials: AD
authors.lastname: Talenfeld
authors.forename: Roman
authors.initials: R
authors.lastname: Raju
authors.forename: David A
authors.initials: DA
authors.lastname: Vorchheimer
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Olin
authors.forename: Michael L
authors.initials: ML
authors.lastname: Marin
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000295:instrumentation*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D054855:Drug-Eluting Stents; D006801:Humans; D006978:Hypertension, Renovascular / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008670:Metals; D011474:Prosthesis Design; D011859:Radiography; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D055502:Secondary Prevention; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D002317:Cardiovascular Agents; D008670:Metals; D020123:Sirolimus