title: Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12.
abstract: Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12 is reported in the form of its octyl glycoside. Syntheses of the 1,2-cis glycosidic linkages have been accomplished by using NIS in conjunction with H(2)SO(4)-silica, and it was found to be stereoselective and productive. The synthesized tetrasaccharide will be utilized as the substrate for galactofuranosyltransferase, WbbI.
authors.affiliation: Indian Institute of Science Education and Research-Kolkata, Mohanpur Campus, P.O. BCKV Campus Main Office, Mohanpur, Nadia, West Bengal, India.
authors.forename: Bimalendu
authors.initials: B
authors.lastname: Roy
authors.forename: Robert A
authors.initials: RA
authors.lastname: Field
authors.forename: Balaram
authors.initials: B
authors.lastname: Mukhopadhyay
mesh_terms: D002240:Carbohydrate Sequence; D048168:Escherichia coli K12 / Q000276:immunology*; D019081:O Antigens / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis*
chemical_list: D019081:O Antigens; D009844:Oligosaccharides