title: Changes in postmenopausal hormone replacement therapy use among women with high cardiovascular risk.
abstract: After randomized trials failed to support the use of hormone replacement therapy (HRT) for preventing cardiovascular disease (CVD), HRT use for postmenopausal women declined. Our analysis of 1999-2000 and 2003-2004 National Health and Nutrition Surveys (NHANES) shows that HRT use decreased 19% (from 27.6 to 8.4%; P<.001) among women with CVD versus 3% (from 19.8 to 16.8%; P=.68) among low-risk women, suggesting that most of the drop in HRT use may be among women prescribed HRT as an unproven treatment to prevent CVD.
authors.affiliation: Columbia Presbyterian Medical Center, New York, NY 10032, USA.
authors.forename: Angela
authors.initials: A
authors.lastname: Hsu
authors.forename: Andrea
authors.initials: A
authors.lastname: Card
authors.forename: Susan Xiaoqin
authors.initials: SX
authors.lastname: Lin
authors.forename: Sean
authors.initials: S
authors.lastname: Mota
authors.forename: Olveen
authors.initials: O
authors.lastname: Carrasquillo
authors.forename: Andrew
authors.initials: A
authors.lastname: Moran
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D015914:Estrogen Replacement Therapy / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009749:Nutrition Surveys; D012307:Risk Factors; D014481:United States