title: Fast and selective extraction of sulfonamides from honey based on magnetic molecularly imprinted polymer.
abstract: A fast and selective method was developed for the determination of sulfonamides (SAs) in honey based on magnetic molecularly imprinted polymer. The extraction was carried out by blending and stirring the sample, extraction solvent and polymers. When the extraction was complete, the polymers, along with the captured analytes, were easily separated from the sample matrix by an adscititious magnet. The analytes eluted from the polymers were determined by liquid chromatography-tandem mass spectrometry. Under the optimal conditions, the detection limits of SAs are in the range of 1.5-4.3 ng g(-1). The relative standard deviations of intra- and interday ranging from 3.7% to 7.9% and from 4.3% to 9.9% are obtained, respectively. The proposed method was successfully applied to determine SAs including sulfadiazine, sulfamerazine, sulfamethoxydiazine, sulfamonomethoxine, sulfadimethoxine, sulfamethoxazole and sulfaquinoxaline in different honey samples. The recoveries of SAs in these samples from 67.1% to 93.6% were obtained.
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Ligang
authors.initials: L
authors.lastname: Chen
authors.forename: Xiaopan
authors.initials: X
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Sun
authors.forename: Yang
authors.initials: Y
authors.lastname: Xu
authors.forename: Qinglei
authors.initials: Q
authors.lastname: Zeng
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Haoyan
authors.initials: H
authors.lastname: Xu
authors.forename: Aimin
authors.initials: A
authors.lastname: Yu
authors.forename: Hanqi
authors.initials: H
authors.lastname: Zhang
authors.forename: Lan
authors.initials: L
authors.lastname: Ding
mesh_terms: D000818:Animals; D001516:Bees; D002853:Chromatography, Liquid; D006722:Honey / Q000032:analysis*; D057230:Limit of Detection; D008280:Magnetics; D054802:Molecular Imprinting; D011108:Polymers / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013449:Sulfonamides / Q000032:analysis / Q000302:isolation & purification*
chemical_list: D011108:Polymers; D013449:Sulfonamides