[The inhibition of the Sonic Hedgehog (SHh) pathway improves the effects of chemotherapy in a model of ductal carcinoma of the pancreas in mice].
Larsen
Christian-Jacques
CJ
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000493:pharmacokinetics / Q000627:therapeutic use; D021441:Carcinoma, Pancreatic Ductal / Q000188:drug therapy* / Q000378:metabolism; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000493:pharmacokinetics / Q000627:therapeutic use; D053823:Hedgehog Proteins / Q000037:antagonists & inhibitors*; D051379:Mice; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D014704:Veratrum Alkaloids / Q000627:therapeutic use*; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D053823:Hedgehog Proteins; C541444:IPI-926; D009363:Neoplasm Proteins; C465570:Shh protein, mouse; D014704:Veratrum Alkaloids; D003841:Deoxycytidine; D000093542:Gemcitabine