Risk factors for the development of ocular tuberculosis in patients with disseminated tuberculosis.
OBJECTIVE
To identify risk factors for the development of ocular tuberculosis in patients with disseminated tuberculosis.


METHODS
A retrospective case-control study. The authors studied all admitted patients with disseminated tuberculosis in two subgroups: patients who developed ocular tuberculosis and those who did not. The potential risk factors analyzed included age, sex, presence of diabetes mellitus, and preexisting immunosuppression.


RESULTS
Of 47 patients, 26 patients (55.3%) developed ocular tuberculosis. Ocular tuberculosis was significantly associated with the presence of preexisting immunosuppression (p = .005) using a logistic regression model. Diabetes mellitus, age, and sex were not risk factors.


CONCLUSIONS
Preexisting immunosuppression is a risk factor.
Mehta
Salil
S
Lilavati Hospital and Research Centre, Ophthalmology Mumbai, India. doc@retinaconsultant.com
D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D014376:Tuberculosis / Q000150:complications* / Q000276:immunology; D014392:Tuberculosis, Ocular / Q000209:etiology*; D055815:Young Adult