title: [Treatment for chronic depression: cognitive behavioral analysis system of psychotherapy (CBASP)].
abstract: BACKGROUND
  Chronic depression is a common disorder in secondary care. Treatment results for this group of depressed patients are often disappointing and the existing treatment protocols are insufficiently tailored to chronic MDD. For this reason, an effective psychotherapeutic treatment will constitute a welcome addition to the range of treatments currently available for chronically depressed patients.
  
  
  OBJECTIVE
  To describe 'cognitive behavioral analysis system of psychotherapy' (CBASP), the first form of psychotherapy specifically designed for the treatment of chronic depression.
  
  
  METHODS
  This article describes the evidence, rational and the most important techniques of CBASP.
  
  
  RESULTS
  In the United States CBASP has proven to be effective in one trial. As a result of these findings, CBASP is recommended in the Dutch treatment guidelines as an evidence-based treatment option for chronic depression. However, the findings have not yet been replicated and little is known about possible ways of implementing CBASP in the Netherlands. For this reason a randomised controlled trial on the effectiveness of CBASP has started in three psychiatric hospitals in the Netherlands.
  
  
  CONCLUSIONS
  CBASP is recommended as a treatment option for chronic depression in the Dutch treatment guidelines, but evidence should be further supported by additional research.
authors.affiliation: Dienst Onderzoek GGZ inGeest/Afdeling Psychiatrie VUmc, Amsterdam. j.wiersma@ggzingeest.nl
authors.forename: J E
authors.initials: JE
authors.lastname: Wiersma
authors.forename: D J F
authors.initials: DJ
authors.lastname: van Schaik
authors.forename: M B J
authors.initials: MB
authors.lastname: Blom
authors.forename: L
authors.initials: L
authors.lastname: Bakker
authors.forename: P
authors.initials: P
authors.lastname: van Oppen
authors.forename: A T F
authors.initials: AT
authors.lastname: Beekman
mesh_terms: D002908:Chronic Disease; D015928:Cognitive Behavioral Therapy; D003866:Depressive Disorder / Q000628:therapy*; D003865:Major Depressive Disorder / Q000628:therapy; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome