title: Influence of narrow band imaging (NBI) videobronchoscopy on the assessment of central lung cancer extension and therapeutic decision.
abstract: OBJECTIVE
  Determination of specificity and sensitivity of narrow band imaging (NBI) in the assessment of tumor extension in centrally located lung cancer, when compared to white light bronchoscopy (WLB) alone, and evaluation of possible influence of NBI on therapeutic decision in patients with lung cancer.
  
  
  METHODS
  We evaluated 36 patients with suspected lung cancer. All patients underwent WLB followed by NBI bronchoscopy. We were using videobronchoscope BF-1T180 and EVIS LUCERA SPECTRUM processor unit.
  
  
  RESULTS
  Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for NBI in the assessment of tumor extension were 97.8, 85, 93.7, and 94.4%, respectively; and for WLB 92.3, 60, 69.6, and 88.9%, respectively. In 14 patients, NBI revealed more extensive tumor than WLB (p =.0057). In eight patients, NBI showed significant influence on therapeutic decision (p =.001).
  
  
  CONCLUSIONS
  NBI videobronchoscopy had better specificity and sensitivity in the assessment of tumor extension in centrally located lung cancer, and it might play a significant role in the therapeutic decision.
authors.affiliation: Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad, Serbia. bojanzaric@neobee.net
authors.forename: Zaric
authors.initials: Z
authors.lastname: Bojan
authors.forename: Perin
authors.initials: P
authors.lastname: Branislav
authors.forename: Jovelic
authors.initials: J
authors.lastname: Aleksandra
authors.forename: Stojanovic
authors.initials: S
authors.lastname: Goran
authors.forename: Ilic D
authors.initials: ID
authors.lastname: Miroslav
authors.forename: Andrijevic
authors.initials: A
authors.lastname: Ilija
authors.forename: Eri
authors.initials: E
authors.lastname: Zivka
authors.forename: Panjkovic
authors.initials: P
authors.lastname: Milana
authors.forename: Secen
authors.initials: S
authors.lastname: Nevena
authors.forename: Antonic
authors.initials: A
authors.lastname: Milan
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D001999:Bronchoscopy / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D018579:Patient Selection; D011013:Pneumonectomy; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014741:Video Recording