Eyeing up new Wnt pathway players.
The Wnt signaling pathway controls cell fate decisions during animal development and the self-renewal and repair of adult tissues. In this issue, Ye et al. (2009) and Junge et al. (2009) reveal how an unusual Wnt receptor-ligand complex associated with a spectrum of retinal diseases instructs vascular development in the retina.
Clevers
Hans
H
Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. h.clevers@hubrecht.eu
D000818:Animals; D006801:Humans; D055495:Neurogenesis; D012160:Retina / Q000378:metabolism*; D012164:Retinal Diseases / Q000378:metabolism; D015398:Signal Transduction; D051153:Wnt Proteins / Q000378:metabolism*
D051153:Wnt Proteins