title: [Two cases of complex sleep apnea syndrome].
abstract: Continuous positive airway pressure (CPAP) therapy of obstructive sleep apnea syndrome (OSAS) is widely accepted. Recently it is reported that central type apnea increases in some patients with OSAS with the application of CPAP, and this type of sleep-disordered breathing is called complex sleep apnea syndrome (comp. SAS). However, until now its concept, mechanism and therapy have not been fully established. We treated 2 cases of comp. SAS with CPAP therapy. When we performed a polysomnography (PSG) examination in case 1 one year later, the symptoms had diminished and the central apnea had decreased, indicating the effectiveness CPAP therapy in case 1. In case 2, the symptoms had not diminished one year later. We therefore performed Adaptive Servo-Ventilation (ASV) therapy, resulting in improvement of symptoms and decrease of the central apnea. CPAP is not always effective in comp. SAS, and ASV can be suitable in such cases.
authors.affiliation: Department of Pulmonary Medicine, Kyoto Prefectural University of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yamada
authors.forename: Taichiro
authors.initials: T
authors.lastname: Arimoto
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Koyama
authors.forename: Asami
authors.initials: A
authors.lastname: Masui
authors.forename: Nobuyo
authors.initials: N
authors.lastname: Tamiya
authors.forename: Shigekuni
authors.initials: S
authors.lastname: Hosogi
authors.forename: Atushi
authors.initials: A
authors.lastname: Hiramatu
authors.forename: Masaki
authors.initials: M
authors.lastname: Nakanishi
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Kohno
authors.forename: Mikio
authors.initials: M
authors.lastname: Ueda
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Marunaka
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011175:Positive-Pressure Respiration / Q000379:methods*; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome