[Up-to-date algorithms for diagnosis and treatment of chronic hepatitis B].
Chronic viral hepatitis B (CHB) is one of the main causes of chronic diffuse diseases of liver. CHB virus (HBV) is identified in 350-400 mln subjects or 5% of the Earth's population including 2.1 mln Russian residents. HBV carriers are at high risk of cirrhosis, hepatic insufficiency and carcinoma which accounts for the estimated 25-40% mortality rate among the infected subjects. The paper presents data on epidemiology and pathogenesis of CHB, its diagnostic and treatment with the use of modern technologies and antiviral agents.
Maev
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Polunina
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Polunina
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D000465:Algorithms; D000998:Antiviral Agents / Q000627:therapeutic use*; D001706:Biopsy; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D006515:Hepatitis B virus / Q000502:physiology*; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D016896:Treatment Outcome; D014779:Virus Replication / Q000187:drug effects*
D000998:Antiviral Agents; D004279:DNA, Viral; D007155:Immunologic Factors