title: Paraneoplastic production of heparin-like anticoagulant in a patient with metastatic transitional cell carcinoma.
abstract: It has been reported that patients with bladder cancer have widely varying paraneoplastic consequences, including metabolic, dermatologic, myopathic and neurologic disturbances. We report a case of a 52-year-old man with advanced transitional cell carcinoma and liver metastases, who developed a severe coagulopathy following robotic radical cystoprostatectomy due to circulating heparin-like substances prior to onset of liver failure. Heparin-like anticoagulant production is a rare paraneoplastic effect documented in concert with transitional cell carcinoma, breast carcinoma and hematological malignancies.
authors.affiliation: Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY.
authors.forename: Kelly N
authors.initials: KN
authors.lastname: Fahl
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Poon
authors.forename: Ketan K
authors.initials: KK
authors.lastname: Badani
authors.forename: Mitchell C
authors.initials: MC
authors.lastname: Benson