Plasmablastic lymphoma in the anal canal.
Plasmablastic lymphoma (PBL) of the oral cavity is an acquired immunodeficiency syndrome-related lymphoma. The immunophenotype of this disease is associated with poor expression of B-cell markers but a positive reactivity for plasma cell markers. PBL is highly aggressive and responds poorly to treatment. Although originally described in the oral cavity, this disease can occur in other body niches. Here, we describe a very rare case of PBL in the anal canal of a 40-year-old woman with human immunodeficiency virus infection. The malignant cells were positive for Epstein-Barr virus and human herpes virus 8.
Lim
Joo Han
JH
Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
Lee
Moon Hee
MH
Lee
Man Jong
MJ
Kim
Chul Soo
CS
Lee
Jin Soo
JS
Choi
Suk Jin
SJ
Yi
Hyeon Gyu
HG