title: Spectral analysis of heart rate variability for early prediction of pregnancy-induced hypertension.
abstract: The early prediction of pregnancy-induced hypertension (PIH), a common morbid disorder of pregnancy is unsatisfactory. Therefore, in the present study we have investigated the role of spectral analysis of heart rate variability (HRV) in the early prediction of PIH. Spectral analysis of HRV was performed in three groups of subjects (Group I: normal pregnant women; Group II: pregnant women with risk factors, but did not develop PIH; Group III: pregnant women with risk factors and developed PIH). It was observed that the LF-HF ratio, the most sensitive indicator of sympathovagal balance, was significantly high (p < 0.01) since early pregnancy in group III compared to other groups, which was significantly correlated with heart rate and blood pressure. It was suggested that the predictive knowledge of sympathovagal imbalance should be utilized in designing the prevention and management of PIH.
authors.affiliation: Department of Physiology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry - 605 006, India. gopalpravati@sify.com
authors.forename: G K
authors.initials: GK
authors.lastname: Pal
authors.forename: P
authors.initials: P
authors.lastname: Shyma
authors.forename: S
authors.initials: S
authors.lastname: Habeebullah
authors.forename: P
authors.initials: P
authors.lastname: Shyjus
authors.forename: Pravati
authors.initials: P
authors.lastname: Pal
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D016022:Case-Control Studies; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology*; D007194:India; D011237:Predictive Value of Tests; D011247:Pregnancy / Q000502:physiology*; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology*; D011261:Pregnancy Trimester, First / Q000502:physiology; D011262:Pregnancy Trimester, Second / Q000502:physiology; D011263:Pregnancy Trimester, Third / Q000502:physiology; D012307:Risk Factors; D013057:Spectrum Analysis; D013564:Sympathetic Nervous System / Q000503:physiopathology; D014630:Vagus Nerve / Q000503:physiopathology