[Research on piezoelectric protein sensor array for rapid detecting HIV(1+2) antibody].
To research piezoelectric immunosensor array for rapid detecting HIV(1+2), piezoelectric immunosensor array matrix was designed. HIV(1+2)C1 antigen was immobilized onto the silver electrodes of quartz-crystal microbalance, which was modified with adsorption and cross-linked method. In the clean air flow and monitoring environment, standard quality control and clinical serum sample were detected. The linear range for the measurement of HIV(1+2) was 0.01-0.2 NCU/ml. The sensitivity, specificity and accuracy of HIV(1+2) piezoelectric protein sensor array were 91.7%, 93.3% and 92.7% respectively.
Wen
Ying
Y
Department of Blood Transfusion, General Hospital of Guangzhou Command, Guangzhou 510010, China. yingw07@126.com
Shan
Guiqiu
G
Pu
Jinhui
J
Liu
Zhongming
Z
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D006678:HIV / Q000302:isolation & purification; D015483:HIV Antibodies / Q000097:blood*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D040081:Protein Array Analysis / Q000295:instrumentation* / Q000379:methods; D011791:Quartz; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D015483:HIV Antibodies; D011791:Quartz