A facile synthesis of deuteroporphyrins derivatives under ultrasound irradiation.
A facile, efficient and general method for preparing deuteroporphyrin derivatives by using concentrated H(2)SO(4) and alcohol under ultrasound irradiation has been developed. A series of new deuteroporphyrin derivatives bearing different propionic ester groups have been synthesized in good yields starting from readily accessible deuterohemin. The characterization of these compounds confirms the synthetic methodology. Compared with conventional methods, the main advantages of the present procedure are shorter reaction time and higher yields.
Hu
Bingcheng
B
School of Chemical Engineering, Nanjing University of Science and Technology, Jiangsu Province, China. hubingcheng@yahoo.com
Zhou
Weiyou
W
Tang
Ying
Y
Huang
Chengmei
C
Liu
Zuliang
Z
D000438:Alcohols / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods; D003905:Deuteroporphyrins / Q000138:chemical synthesis*; D004952:Esters / Q000737:chemistry; D006427:Hemin / Q000031:analogs & derivatives* / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D008956:Models, Chemical; D011166:Porphyrins / Q000737:chemistry; D013464:Sulfuric Acids / Q000737:chemistry; D014465:Ultrasonics
D000438:Alcohols; D003905:Deuteroporphyrins; D004952:Esters; D008670:Metals; D011166:Porphyrins; D013464:Sulfuric Acids; C011219:deuterohemin; C028839:deuteroporphyrin-IX; D006427:Hemin; C033158:sulfuric acid