title: [Wavefront-guided and wavefront-optimised LASEK--comparison of clinical results].
abstract: OBJECTIVE
  The aim of this study was to compare refractive outcomes and wavefront results in eyes undergoing wavefront-optimised and wavefront-guided LASEK.
  
  
  METHODS
  In this contralateral eye study wavefront-guided LASEK and wavefront-optimised LASEK have been carried out on 30 eyes each. Preoperatively, 1 month, 3 months and 6 months after surgery a full ophthalmological examination was carried out. Preoperatively and 6 months postoperatively additional wavefront measurement have been carried out on all patients.
  
  
  RESULTS
  The mean preoperative refraction in the wavefront-guided group was -4.41 D (SD 1.38 D) and in the wavefront-optimised group -4.62 D (SD 1.86 D). The postoperative refraction was very good in both groups (wavefront-guided -0.06 D, SD 0.18 D; wavefront-optimised -0.03 D, SD 0.21 D). In both groups RMS of higher orders were increased slightly (wavefront-guided from 0.26 to 0.31 microm, wavefront-optimised from 0.27 to 0.32 microm) and also spherical aberrations increased slightly (wavefront-guided from 0.18 to 0.23 microm, wavefront-optimised from 0.16 to 0.21 microm).
  
  
  CONCLUSIONS
  The refractive results with the Concept System 500 in patients with preoperatively low amounts of higher order aberrations after wavefront-guided and wavefront-optimised LASEK are comparable. As good wavefront measurements need a lot of experience and take a lot of time, there is no advantage of wavefront-guided ablation in patients with low preoperative aberrations.
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, 81675 München. christoph.wvm@web.de
authors.forename: C Winkler
authors.initials: CW
authors.lastname: von Mohrenfels
authors.forename: R
authors.initials: R
authors.lastname: Khoramnia
authors.forename: J
authors.initials: J
authors.lastname: Salgado
authors.forename: M M
authors.initials: MM
authors.lastname: Maier
authors.forename: C
authors.initials: C
authors.lastname: Lohmann
mesh_terms: D000328:Adult; D057108:Corneal Wavefront Aberration / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D012029:Refraction, Ocular; D014792:Visual Acuity; D055815:Young Adult