Iridium-catalyzed enantioselective hydrogenation of vinyl boronates.
The first Ir-catalyzed asymmetric hydrogenations of vinyl boronates have been performed using low catalyst loadings (0.5 mol%) and pressure (as low as 1 bar). Good selectivities (76-98% ee) were obtained for a range of substrates.
Paptchikhine
Alexander
A
Dept. of Biochemistry and Organic Chemistry, Uppsala University, Husargatan 3, Uppsala, Sweden.
Cheruku
Pradeep
P
Engman
Mattias
M
Andersson
Pher G
PG
D002384:Catalysis; D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D008958:Models, Molecular; D009943:Organophosphorus Compounds; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
D009943:Organophosphorus Compounds; D014753:Vinyl Compounds; D007495:Iridium