title: Practical disk diffusion test for detecting group B streptococcus with reduced penicillin susceptibility.
abstract: Although group B streptococcus (GBS) has been considered to be uniformly susceptible to beta-lactams, the presence of GBS with reduced penicillin susceptibility (PRGBS) was recently confirmed genetically. We developed a feasible and reliable method for screening PRGBS in clinical microbiology laboratories using a combination of ceftibuten, oxacillin, and ceftizoxime disks.
authors.affiliation: Department of Bacteriology II, National Institute of Infectious Disease, Tokyo 208-0011, Japan.
authors.forename: Kouji
authors.initials: K
authors.lastname: Kimura
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Wachino
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kurokawa
authors.forename: Satowa
authors.initials: S
authors.lastname: Suzuki
authors.forename: Kunikazu
authors.initials: K
authors.lastname: Yamane
authors.forename: Naohiro
authors.initials: N
authors.lastname: Shibata
authors.forename: Yoshichika
authors.initials: Y
authors.lastname: Arakawa
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000077722:Ceftibuten; D015296:Ceftizoxime / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests / Q000379:methods*; D006801:Humans; D010068:Oxacillin / Q000494:pharmacology; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins; D015296:Ceftizoxime; D000077722:Ceftibuten; D010068:Oxacillin