Design of membrane proteins: toward functional systems.
Over the years, membrane-soluble peptides have provided a convenient model system to investigate the folding and assembly of integral membrane proteins. Recent advances in experimental and computational methods are now being translated into the design of functional membrane proteins. Applications include artificial modulators of membrane protein function, inhibitors of protein-protein interactions, and redox membrane proteins.
Ghirlanda
Giovanna
G
Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85827, United States. gghirlanda@asu.edu
D000818:Animals; D015195:Drug Design; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism*; D010084:Oxidation-Reduction; D011485:Protein Binding; D017510:Protein Folding
D008565:Membrane Proteins