Donor factors that affect the number of organs transplanted per donor.
BACKGROUND
Demographic factors and factors from donors' medical and social history influence the number of organs transplanted per donor. The goal for organ procurement organizations is 4.30 organs transplanted per standard criteria donor.


OBJECTIVE
To examine the influence of factors related to donors' demographics and donors' medical and social histories on the number of organs transplanted per donor.


METHODS
The medical and social histories of 772 deceased donors were reviewed to assess demographic factors (eg, age, sex), diseases (eg, heart disease, hepatitis, diabetes, hypertension), and other factors (eg, body mass index, high-risk behavior, alcohol abuse). Statistics were calculated by using MarketSight software.


RESULTS
Between 2003 and 2007, 2409 organs were recovered and transplanted from 772 donors (number of organs per donor, mean [SD], 3.12 [1.73]) in our designated service area. Some demographic factors (eg, age, sex) were associated with significantly fewer organs transplanted per donor. Other factors from donors' medical and social histories also played a major role, with each added factor significantly decreasing the number of organs transplanted per donor. The number of organs transplanted differed significantly between donors with 0 vs 1, 1 vs 2, and 2 vs 3 or more factors related to their medical and social histories.


CONCLUSIONS
Demographic factors and other factors in donors' medical and social histories significantly reduced the number of organs transplanted per donor. An algorithm that uses all potential demographic factors and factors related to medical and social history nested within each other could be developed to predict number of organs transplanted.
Olson
Leslie
L
LifeCenter Northwest, Bellevue, WA 98004, USA. leso@lcnw.org
Cravero
Lynn
L
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000465:Algorithms; D000704:Analysis of Variance; D015992:Body Mass Index; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D046148:Donor Selection / Q000458:organization & administration*; D005260:Female; D006085:Graft Survival; D006304:Health Status; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D018709:Statistics, Nonparametric; D019966:Substance-Related Disorders / Q000150:complications; D009927:Tissue and Organ Procurement / Q000458:organization & administration*; D014481:United States / Q000453:epidemiology