title: [The epidemiology of congenital heart disease in Asturias (Spain) during the period 1990-2004].
abstract: BACKGROUND
  Congenital heart diseases (CHDs) are the most common type of birth defect.
  
  
  OBJECTIVE
  The purpose of this investigation was to assess the prevalence and trends of CHDs, and to describe the associated malformations and syndromes or sequences in a geographically defined population.
  
  
  METHODS
  Data were collected from the Asturias Registry of Congenital Defects. The period studied was from 1990 to 2004, and the study population was the 103,452 births of mothers living in the region. Total prevalence and birth prevalence were calculated.
  
  
  RESULTS
  A total of 3035 cases with congenital defects were recorded, of these 778 had CHDs. The total prevalence was 75.2 per 10,000 births, with an upward trend during this period. The most common CHDs were: ventricular septal defects (28.8 per 10,000 births), atrial septal defects (10.3 per 10,000 births) and patent ductus arteriosus (6.0 per 10,000 births). A total of 73.6% of CHDs occurred as isolated defects, 12.5% with other congenital defects and 14% were syndromes or sequences. Prenatal diagnosis was effective in only 7.3% (3.8% in isolated cases).
  
  
  CONCLUSIONS
  The prevalence of CHDs in Asturias over this period falls within the range reported for other European registries. The apparent increase in prevalence of CHD results mainly from improved diagnosis of minor defects, but there has been no change over time in birth prevalence of more serious defects.
authors.affiliation: Servicio de Pediatría, Hospital San Agustín, Avilés, Asturias, España. crdehli@yahoo.es
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez Dehli
authors.forename: F
authors.initials: F
authors.lastname: Ariza Hevia
authors.forename: I
authors.initials: I
authors.lastname: Riaño Galán
authors.forename: C
authors.initials: C
authors.lastname: Moro Bayón
authors.forename: E
authors.initials: E
authors.lastname: Suárez Menéndez
authors.forename: C
authors.initials: C
authors.lastname: Mosquera Tenreiro
authors.forename: E
authors.initials: E
authors.lastname: García López
mesh_terms: D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology*; D006331:Heart Diseases / Q000151:congenital* / Q000453:epidemiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013030:Spain / Q000453:epidemiology; D013997:Time Factors