Hypothalamic nonapeptidergic regulation of cell and tissue homeostasis: interactions of pro- and eukaryotes.
Data on the structural-functional organization of the hypothalamic nonapeptidergic neurosecretory system in mammals and its role in regulating the adaptive reactions of animals are presented; reports describing the biological features of interactions between pro- and eukaryotes in in situ conditions and on cultivation and in experimental pathology are summarized. Morphofunctional criteria are established on the basis of contemporary morphological approaches to allow effective evaluation of the range of histoblastic and organotypic potentials of the visceral organs and their compensatory-adaptive capacities realized under hypothalamic neuroendocrine control and seen on interactions with bacterial pathogens. Emphasis is placed on experimental histological grounds for new methods for the complex treatment of wound and purulent-necrotic processes, including the use of hypothalamic nonapeptides (oxytocin).
Stadnikov
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Department of Histology, Cytology, and Embryology, Orenburg State Medical Academy, Orenburg, Russia. orgma@esoo.ru
D000818:Animals; D001412:Bacillus subtilis / Q000502:physiology; D018988:Bacterial Translocation; D011992:Endosomes / Q000382:microbiology / Q000502:physiology; D004848:Epithelium / Q000382:microbiology / Q000502:physiology; D004912:Erythrocytes / Q000382:microbiology; D006056:Golgi Apparatus / Q000378:metabolism / Q000382:microbiology; D006706:Homeostasis; D007031:Hypothalamus / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000382:microbiology; D009474:Neurons / Q000378:metabolism; D009490:Neurosecretory Systems / Q000502:physiology*; D013203:Staphylococcal Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology; D013210:Staphylococcus / Q000502:physiology