Methionine can favor DNA platination by trans-coordinated platinum antitumor drugs.
Li
Chan
C
Department of Chemistry, University of Science and Technology of China, Hefei Anhui, China.
Li
Zhanyong
Z
Sletten
Einar
E
Arnesano
Fabio
F
Losacco
Maurizio
M
Natile
Giovanni
G
Liu
Yangzhong
Y
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D002945:Cisplatin / Q000737:chemistry / Q000494:pharmacology; D004247:DNA / Q000187:drug effects; D004249:DNA Damage; D006801:Humans; D008715:Methionine / Q000737:chemistry*; D009944:Organoplatinum Compounds / Q000737:chemistry* / Q000494:pharmacology
D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D004247:DNA; D008715:Methionine; D002945:Cisplatin