title: [Neurosjögren: an unusual presentation with central nervous system involvement].
abstract: BACKGROUND
  Neurological manifestations in Sjögren's syndrome are variable. The peripheral nervous system is generally involved. We report a rare case of an unusual central neurological manifestation.
  
  
  METHODS
  A 54-year-old woman was admitted with headache and tetraparesia. The physical examination revealed a tetrapyramidal syndrome and a bilateral parotidomegaly. The patient's general condition was nevertheless quite good. Brain MRI showed an heterogeneous pontine lesion with multiple nodular formations in the periventricular white matter. Blood tests revealed anti-SSA and anti-SSB antibodies. A labial salivary gland biopsy was grade IV in Chisholm scoring system and Schirmer's test was positive.
  
  
  CONCLUSIONS
  A latent Sjögren's syndrome can lead to a wide variety of focal brain MRI abnormalities and should be evoked when the etiology is not clear.
authors.affiliation: Service de Médecine Interne, Hôpital Ibn Tofail, CHU Mohamed VI, Marrakech, Maroc.
authors.forename: L
authors.initials: L
authors.lastname: Essaadouni
authors.forename: F
authors.initials: F
authors.lastname: Jghaimi
authors.forename: N
authors.initials: N
authors.lastname: Kissani
mesh_terms: D001706:Biopsy; D002493:Central Nervous System Diseases / Q000209:etiology / Q000473:pathology*; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010306:Parotid Gland / Q000473:pathology; D011149:Pons / Q000473:pathology; D011782:Quadriplegia / Q000209:etiology; D012859:Sjogren's Syndrome / Q000150:complications / Q000473:pathology*