[Experimental study of skin toxicity of Xiaoer Reqing massage gel].
OBJECTIVE
To study the skin toxicity of Xiaoer Reqing massage gel in guinea pigs.


METHODS
Acute skin toxicity and skin hypersensitivity tests of the gel were performed in healthy juvenile guinea pigs, and skin irritation test was carried out in healthy juvenile rabbits.


RESULTS
Xiaoer Reqing massage gel produced no acute toxicity or cutaneous stimulation to intact or damaged skin of guniea pigs and rabbits, nor did the gel elicited hypersensitivity response in the intact skin of the guinea pigs.


CONCLUSIONS
Xiaoer Reqing massage gel is safe as an adjuvant of acute upper respiratory infection in children.
Liu
Li
L
College of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China. shyshll@163.com
Liu
Qiang
Q
D000279:Administration, Cutaneous; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000633:toxicity*; D005260:Female; D005782:Gels; D006168:Guinea Pigs; D008297:Male; D011817:Rabbits; D011897:Random Allocation; D012867:Skin / Q000187:drug effects*; D018675:Toxicity Tests
D004365:Drugs, Chinese Herbal; D005782:Gels