Aliphatic imines in titanium-mediated reductive cross-coupling: unique reactivity of Ti(O-i-Pr)4/n-BuLi.
A procedure for the coupling of aliphatic imines with allylic and allenic alkoxides is described. The success of these studies was enabled by a unique reactivity profile of Ti(IV) isopropoxide/n-BuLi compared to well-known Ti(IV) isopropoxide/RMgX systems.
Tarselli
Michael A
MA
Department of Chemistry, The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458, USA.
Micalizio
Glenn C
GC
D000438:Alcohols / Q000737:chemistry; D007097:Imines / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D014025:Titanium / Q000737:chemistry*
D000438:Alcohols; D007097:Imines; D009942:Organometallic Compounds; C046771:butyllithium; D014025:Titanium