[Therapeutic strategy for pheochromocytoma].
Pheochromocytoma is the most common type of neuroendocrine tumor arising from the adrenal gland. Pheochromocytoma has been termed a 10% tumor because roughly 10% of such tumors are malignant, multifocal, bilateral, and arise in extra-adrenal sites. During the last decade, laparoscopic adrenalectomy has been the standard method to remove pheochromocytomas. Adrenal-sparing laparoscopic surgery is a treatment of choice for bilateral pheochromocytomas. Cyclophosphamide, vincristine and dacarbazine combined chemotherapy and (131)I-MIBG therapy are required for the treatment of metastatic or unresectable malignant pheochromocytoma.
Iihara
Masatoshi
M
Dept. of Endocrine Surgery, Tokyo Women's Medical University, Shinjuka-ku, Tokyo, Japan.
D000310:Adrenal Gland Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery*; D000315:Adrenalectomy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006801:Humans; D010535:Laparoscopy; D010673:Pheochromocytoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery*