Vascular wall invasion in neurofibromatosis-induced aortic rupture.
Neurofibromatosis type 1 (NF-1) is an autosomal dominant disease primarily characterized by cutaneous café au lait macules, benign neurofibromas, and iris hamartomas. A spectrum of vascular abnormalities is associated with NF-1. We present a case of a 49-year-old female with NF-1 and spontaneous rupture of the infrarenal aorta caused by invasion of a neurofibroma and treated with endovascular stent grafting.
Falcone
John L
JL
Division of Vascular Surgery, Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Go
Michael R
MR
Baril
Donald T
DT
Oakley
Gerard J
GJ
Makaroun
Michel S
MS
Chaer
Rabih A
RA
D001012:Aorta, Abdominal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D001027:Aortography / Q000379:methods; D001344:Autopsy; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D017809:Fatal Outcome; D005260:Female; D006406:Hematoma / Q000209:etiology; D006801:Humans; D002534:Hypoxia, Brain / Q000209:etiology; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome