title: The use of covariance models to annotate RNAs in whole genomes.
abstract: In this review we discuss bioinformatic issues in non-coding RNA analysis, in particular the annotation of genome sequences using covariance models. Some recent innovations for improving the speed and accuracy of covariance models is discussed.
authors.affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK. pg5@sanger.ac.uk
authors.forename: Paul P
authors.initials: PP
authors.lastname: Gardner
mesh_terms: D000818:Animals; D019295:Computational Biology; D016678:Genome; D006801:Humans; D008957:Models, Genetic; D015233:Models, Statistical; D022661:RNA, Untranslated / Q000032:analysis / Q000235:genetics*; D017423:Sequence Analysis, RNA
chemical_list: D022661:RNA, Untranslated