title: Efficient synthesis of dendrimers via a thiol-yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs.
abstract: A combination of thiol-yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.
authors.affiliation: Centre for Advanced Macromolecular Design (CAMD), School of Chemical Science and Engineering, The University of New South Wales, Sydney, NSW 2052, Australia.
authors.forename: Gaojian
authors.initials: G
authors.lastname: Chen
authors.forename: Jatin
authors.initials: J
authors.lastname: Kumar
authors.forename: Andrew
authors.initials: A
authors.lastname: Gregory
authors.forename: Martina H
authors.initials: MH
authors.lastname: Stenzel
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D050091:Dendrimers / Q000138:chemical synthesis*; D004337:Drug Carriers / Q000138:chemical synthesis*; D004951:Esterification; D017671:Platinum Compounds / Q000008:administration & dosage; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D050091:Dendrimers; D004337:Drug Carriers; D017671:Platinum Compounds; D013438:Sulfhydryl Compounds