The microscopic agglutination test (MAT) is an unreliable predictor of infecting Leptospira serovar in Thailand.
A prospective study in Thailand identified 106 patients with culture-proven leptospirosis. The accuracy of the microscopic agglutination test (MAT) in predicting the infecting serovar was evaluated in 78/106 (74%) patients with a diagnostic titer. MAT correctly determined the infecting serovar in 26 cases (33%), indicating that this assay is a poor predictor of infecting serovar in our setting.
Smythe
Lee D
LD
WHO/FAO/OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Disease Unit, Queensland Health Scientific Services, Brisbane, Australia.
Wuthiekanun
Vanaporn
V
Chierakul
Wirongrong
W
Suputtamongkol
Yupin
Y
Tiengrim
Surapee
S
Dohnt
Michael F
MF
Symonds
Meegan L
ML
Slack
Andrew T
AT
Apiwattanaporn
Apichat
A
Chueasuwanchai
Sunee
S
Day
Nicholas P
NP
Peacock
Sharon J
SJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D000372:Agglutination Tests / Q000379:methods*; D005260:Female; D006801:Humans; D007919:Leptospira / Q000145:classification*; D007922:Leptospirosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D008297:Male; D008853:Microscopy / Q000379:methods*; D008875:Middle Aged; D011237:Predictive Value of Tests; D013785:Thailand / Q000453:epidemiology; D055815:Young Adult