title: Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.
authors.affiliation: Universite Paul Sabatier Toulouse III, Faculte des Sciences Pharmaceutiques, Laboratoire de Pharmacochimie des Substances Naturelles et Pharmacophores Redox, UMR152 IRD-UT3, 31062 Toulouse cedex 09, France. romain.duval@ird.fr
authors.forename: Romain
authors.initials: R
authors.lastname: Duval
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Kolb
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Braud
authors.forename: David
authors.initials: D
authors.lastname: Genest
authors.forename: Christiane
authors.initials: C
authors.lastname: Garbay
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000032:analysis* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D020687:cdc25 Phosphatases / Q000037:antagonists & inhibitors*
chemical_list: D004791:Enzyme Inhibitors; D011743:Pyrimidines; D013844:Thiazoles; D014230:Triazoles; D020687:cdc25 Phosphatases