title: African American female with renal failure presenting with skin lesions: a case report.
abstract: Calciphylaxis is a lethal disorder seen in patients with end-stage renal disease and is characterized by painful necrotic skin lesions. The pathophysiology is still unknown. Elevated calcium, phosphorous and parathormone appear to play a role in causing small and medium sized vasculopathy. Diagnosis is delayed, prognosis is poor and mortality remains high. In this article we describe the case of calciphylaxis in a patient with chronic renal failure and multiple medical comorbidities, and discuss diagnostic management, prognosis and treatment options.
authors.affiliation: Department of Family Medicine and Public Health Sciences, Wayne State University 1100, W. University Drive, Rochester Hills, Michigan 48307 USA. smaniyam@med.wayne.edu
authors.forename: Sajitha Mf
authors.initials: SM
authors.lastname: Rahman
authors.forename: Nejla
authors.initials: N
authors.lastname: Israel
authors.forename: Tsveti
authors.initials: T
authors.lastname: Markova