Recurrent pulmonary embolism associated with a hemostatic drug: tranexamic acid.
Tranexamic acid (TA) used in a variety of conditions associated with bleeding has been associated with potential thrombotic side effects such as formation of thrombi and pulmonary embolism (PE). We describe a case of a woman with chronic hemoptysis and a history of PE, who recently used TA as a prophylactic measure, which could have resulted in a new episode of PE. Tranexamic acid probably played a contributory role in the development of her second PE.
Krivokuca
I
I
Department of Respiratory Medicine, Division of Heart & Lungs, University Medical Centre Utrecht, Heidelberglaan, Utrecht, Netherlands. i.krivokuca@umcutrecht.nl
Lammers
J-W J
JW
D000933:Antifibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D006469:Hemoptysis / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000139:chemically induced*; D012008:Recurrence; D014148:Tranexamic Acid / Q000008:administration & dosage / Q000009:adverse effects*
D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid