Comparison of pregnancy outcomes in anonymous shared versus exclusive donor oocyte in vitro fertilization cycles.
OBJECTIVE
To determine whether there is a difference in pregnancy outcomes between women undergoing a shared versus exclusive donor oocyte cycle.


METHODS
Retrospective analysis.


METHODS
University IVF center.


METHODS
Women undergoing either a shared (n=656 cycles), exclusive (n=225 cycles), or shared converted to exclusive (n=22 cycles) donor oocyte cycle from January 2000-December 2005.


METHODS
None.


METHODS
Number of eggs retrieved, eggs fertilized, embryos transferred, embryos cryopreserved, clinical pregnancy rates (PR), live birth rates, spontaneous abortion rates.


RESULTS
Pregnancy outcomes in 656 shared cycles were compared with 225 exclusive cycles and 22 shared converted to exclusive donor oocyte cycles. Overall, there was no difference in the clinical PR among the three groups; however, the exclusive group did have a significantly greater number of embryos cryopreserved and this event occurred more frequently in such a cycle.


CONCLUSIONS
Women undergoing a donor oocyte IVF cycle can choose to share the donor's oocytes with another recipient without compromising their PR; however, the probability of cryopreservation in such a shared donor oocyte cycle is significantly reduced. Therefore, the recipient must weigh the financial burden of an exclusive cycle with the desires for cryopreservation in an IVF cycle.
Mullin
Christine M
CM
NYU Fertility Center, New York University, 660 First Avenue, 5th Floor, New York, NY 10016, USA. christine.mullin@gmail.com
Fino
M Elizabeth
ME
Talebian
Sheeva
S
Keegan
Debbra
D
Grifo
Jamie A
JA
Licciardi
Frederick
F
D000328:Adult; D015925:Cryopreservation / Q000379:methods; D004624:Embryo Transfer / Q000379:methods; D004717:Endometrium / Q000033:anatomy & histology; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D005498:Follicular Phase / Q000502:physiology; D005615:Freezing; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology; D008875:Middle Aged; D018587:Oocyte Donation / Q000145:classification* / Q000706:statistics & numerical data; D054315:Oocyte Retrieval; D009865:Oocytes / Q000166:cytology / Q000502:physiology; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D018873:Pregnancy Rate; D012189:Retrospective Studies; D056826:Single Embryo Transfer
D004958:Estradiol