[Antitumor drug delivery system: the progress of researches on block copolymer micelle and its compositive materials].
In antitumor drug delivery system, the block copolymer micelle is a sort of new colloidal state drug carrier in recent years, and it has lots of remarkable properties such as high stability in vitro and in vivo, favourable biocompatibility, controlling of drug release, and targeting to tumor tissue. At present, a great deal of researches have been madeon its compositive materials. Except commonly used micelle materials, the new developmental intelligent micelle materials have been becoming the hotspots of researches on block copolymer micelle. This review is presented with emphasis on the block copolymer micelle and its compositive materials.
Yan
Ke
K
College of Pharmacy, Chongqing University of Medical Sciences, Chongqing 400016, China.
Wang
Chi
C
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D003692:Delayed-Action Preparations / Q000008:administration & dosage / Q000493:pharmacokinetics; D004337:Drug Carriers / Q000008:administration & dosage / Q000493:pharmacokinetics; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008823:Micelles; D009369:Neoplasms / Q000188:drug therapy; D011108:Polymers / Q000737:chemistry*
D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D008823:Micelles; D011108:Polymers