title: Reactions to resin-based dental materials in patients--type, time to onset, duration, and consequence of the reaction.
abstract: OBJECTIVE
  The aim of the present study was to determine the types of side-effects occurring and for how long they lasted in a group of patients with side-effects assessed to be caused by resin-based materials.
  
  
  METHODS
  A total of 618 reports were received by the Swedish National Register of Side-Effects to Dental Materials, among which 36 were on patients with reactions assessed to be caused by resin-based restorative materials. The group examined consisted of 25 women and 11 men, with a mean age of 47.8 +/- 15.6 years. A follow-up was done through a structured telephone interview.
  
  
  RESULTS
  The majority of symptoms were intra-oral or a combination of intra-oral and extra-oral symptoms that appeared within the first 24 hr after treatment. The most common adverse effects reported were skin problems, oral ulcers, and burning mouth. Within less than a week, the reactions had disappeared in 50% of the patients.
  
  
  CONCLUSIONS
  Immediate reactions to resin-based materials were more prevalent than delayed allergic reactions, and the mechanism of the immediate reactions is probably non-allergic in most cases. There is a need for developing provocation tests to verify the association between the reaction and the material, and also to identify the offending component.
authors.affiliation: Faculty of Medicine, Institute of Clinical Dentistry, University of Tromsø/Public Dental Service Competence Centre of Northern Norway, 9018 Tromsø, Norway. anders.tillberg@uit.no
authors.forename: Anders
authors.initials: A
authors.lastname: Tillberg
authors.forename: Berndt
authors.initials: B
authors.lastname: Stenberg
authors.forename: Anders
authors.initials: A
authors.lastname: Berglund
mesh_terms: D000293:Adolescent; D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D002648:Child; D003188:Composite Resins / Q000009:adverse effects*; D003764:Dental Materials / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000150:complications / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D016273:Occupational Exposure; D010328:Patch Tests; D012042:Registries; D013997:Time Factors
chemical_list: D003188:Composite Resins; D003764:Dental Materials