[Myosins in nucleus].
Myosins, actin-dependent molecular motors are expressed in almost all eukaryotic cells where are engaged in a panoply of cellular processes such as muscle contraction, cell migration and adhesion, intracellular trafficking, cytokinesis, endocytosis and secretion. In recent years a number of reports has been published revealing nuclear localization of myosins as well as actin and actin-binding proteins. Namely, nuclear form of myosin IC (NMI), myosin VI, myosin XVIB and myosin XVIIIB were found in nucleus. NMI and myosin VI seem to be involved in gene transcription and possibly intranuclear transport. In this paper, current knowledge on the role of myosin motors in nucleus has been presented.
Sobczak
Magdalena
M
Pracownia Molekularnych Podstaw Ruchów Komórkowych, Zakład Biochemii, Instytut Biologii Doświadczalnej im. M. Nenckiego PAN, Warszawa.
Majewski
Łukasz
Ł
Redowicz
Maria Jolanta
MJ
D000199:Actins / Q000378:metabolism; D021581:Active Transport, Cell Nucleus / Q000502:physiology; D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002467:Cell Nucleus / Q000378:metabolism*; D006801:Humans; D008840:Microfilament Proteins / Q000378:metabolism; D009119:Muscle Contraction / Q000502:physiology; D018995:Myosin Heavy Chains / Q000378:metabolism; D009218:Myosins / Q000378:metabolism*; D014158:Transcription, Genetic / Q000502:physiology
D000199:Actins; D008840:Microfilament Proteins; C089785:myosin VI; D018995:Myosin Heavy Chains; D009218:Myosins