Unraveling bacterial interactions with toll-like receptors.
Bacterial diversity, tight regulation of Toll-like receptor function, and the variation of cellular phenotypes dependent on the local microenvironment, are increasingly recognized as key factors in maintaining immune homeostasis. Here we discuss bacterial and host factors important for a balanced immune response during infection.
van Putten
Jos P M
JP
Department of Infectious Diseases & Immunology, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands. j.vanputten@uu.nl
Bouwman
Lieneke I
LI
de Zoete
Marcel R
MR
D000818:Animals; D000940:Antigenic Variation; D000942:Antigens, Bacterial / Q000276:immunology*; D001424:Bacterial Infections / Q000276:immunology*; D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013045:Species Specificity; D051193:Toll-Like Receptors / Q000276:immunology*
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; D051193:Toll-Like Receptors