Optical signal comparison of single fluorescent molecules and Raman active gold nanostars.
The relevant photophysical properties of single fluorescent molecules and single SERS active surface-coated gold nanostars tagged with the Raman reporter molecule 4-mercaptopyridine are compared for imaging purposes. Mean count rate distributions are built from the single molecule/single probe level. The individually observed variance and count rates of both systems are compared as well as the behavior over multiple image acquisitions.
Allgeyer
Edward S
ES
Department of Physics and Astronomy, Department of Chemical and Biological Engineering, University of Maine, Orono, Maine 04469, USA.
Pongan
Adam
A
Browne
Michael
M
Mason
Michael D
MD