title: Subcutaneous metastasis of prostate cancer.
abstract: OBJECTIVE
  Prostate cancer tends to spread to regional lymph nodes and bone, and, to a lesser degree, to lung, liver, and brain. Metastases in other locations are exceptional. To review the frequency and clinical characteristics of metastasis to subcutaneous cellular tissue in adenocarcinoma of the prostate.
  
  
  METHODS
  The case of a 71-year-old man diagnosed of adenocarcinoma of the prostate is reported. The patient underwent radical prostatectomy and artificial sphincter for stress urinary incontinence.
  
  
  RESULTS
  During follow-up the patient showed biochemical progression, local recurrence, and bone metastasis. The disease metastasized in the subcutaneous tissue around the reservoir of the artificial sphincter.
  
  
  CONCLUSIONS
  Prostate cancer is highly prevalent in our part of the world. The clinical finding of metastasis in organs other than bone or regional lymph nodes is accompanied by a short survival. Metastases in subcutaneous tissue may be underdiagnosed due to its indolent clinical course and possible absence of PSA elevation. In any case, subcutaneous metastases have an unfavorable prognosis.
authors.affiliation: Urology Department I, Central University Hospital of Asturias, Oviedo, Spain. mirandaaranzubia@gmail.com
authors.forename: Oscar Miranda
authors.initials: OM
authors.lastname: Aranzubía
authors.forename: Jorge García
authors.initials: JG
authors.lastname: Rodríguez
authors.forename: Blanca Vivanco
authors.initials: BV
authors.lastname: Allende
authors.forename: Jesús María Fernández
authors.initials: JM
authors.lastname: Gómez
authors.forename: Raquel Sacristán
authors.initials: RS
authors.lastname: González
authors.forename: Miguel Alvarez
authors.initials: MA
authors.lastname: Múgica
authors.forename: Francisco Javier Regadera
authors.initials: FJ
authors.lastname: Sejas
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D040521:Subcutaneous Tissue