title: Outcome domains for studies of acute and chronic gout.
abstract: Discussion and voting at OMERACT 9 confirmed 5 essential domains for outcomes of acute gout: pain, joint swelling, joint tenderness, patient global assessment and activity limitations. For studies in chronic gout 7 essential domains are: serum urate, acute gout attacks, tophus burden, health-related quality of life, activity limitations, pain, and patient global assessment. Implications of patient perspectives, discretionary domains for specific studies, measurement instruments and a possible responder index are under study.
authors.affiliation: Rheumatology Section, Veterans Affairs Medical Center, University & Woodland Avenues, Philadelphia, Pennsylvania 19104, USA. schumacr@mail.med.upenn.edu
authors.forename: H Ralph
authors.initials: HR
authors.lastname: Schumacher
authors.forename: William
authors.initials: W
authors.lastname: Taylor
authors.forename: Lawrence
authors.initials: L
authors.lastname: Edwards
authors.forename: Rebecca
authors.initials: R
authors.lastname: Grainger
authors.forename: Naomi
authors.initials: N
authors.lastname: Schlesinger
authors.forename: Nicola
authors.initials: N
authors.lastname: Dalbeth
authors.forename: Francisca
authors.initials: F
authors.lastname: Sivera
authors.forename: Jasvinder
authors.initials: J
authors.lastname: Singh
authors.forename: Robert
authors.initials: R
authors.lastname: Evans
authors.forename: Royce W
authors.initials: RW
authors.lastname: Waltrip
authors.forename: Cesar
authors.initials: C
authors.lastname: Diaz-Torne
authors.forename: Patricia
authors.initials: P
authors.lastname: MacDonald
authors.forename: Fiona
authors.initials: F
authors.lastname: McQueen
authors.forename: Fernando
authors.initials: F
authors.lastname: Perez-Ruiz
mesh_terms: D000208:Acute Disease; D018771:Arthralgia / Q000503:physiopathology; D002908:Chronic Disease; D032921:Consensus; D004185:Disability Evaluation; D006073:Gout / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000592:standards*; D011788:Quality of Life; D012720:Severity of Illness Index; D014527:Uric Acid / Q000097:blood
chemical_list: D014527:Uric Acid