title: [Experimental study of skin toxicity of Xiaoer Reqing massage gel].
abstract: OBJECTIVE
  To study the skin toxicity of Xiaoer Reqing massage gel in guinea pigs.
  
  
  METHODS
  Acute skin toxicity and skin hypersensitivity tests of the gel were performed in healthy juvenile guinea pigs, and skin irritation test was carried out in healthy juvenile rabbits.
  
  
  RESULTS
  Xiaoer Reqing massage gel produced no acute toxicity or cutaneous stimulation to intact or damaged skin of guniea pigs and rabbits, nor did the gel elicited hypersensitivity response in the intact skin of the guinea pigs.
  
  
  CONCLUSIONS
  Xiaoer Reqing massage gel is safe as an adjuvant of acute upper respiratory infection in children.
authors.affiliation: College of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China. shyshll@163.com
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000633:toxicity*; D005260:Female; D005782:Gels; D006168:Guinea Pigs; D008297:Male; D011817:Rabbits; D011897:Random Allocation; D012867:Skin / Q000187:drug effects*; D018675:Toxicity Tests
chemical_list: D004365:Drugs, Chinese Herbal; D005782:Gels