Homeostasis in infected epithelia: stem cells take the lead.
To maintain tissue homeostasis and avoid disease, epithelial cells damaged by pathogens need to be readily replenished, and this is mainly achieved by the activation of stem cells. In this Short Review, we discuss recent developments in the exciting field of host epithelia-pathogen interaction in Drosophila as well as in mammals.
Pitsouli
Chrysoula
C
Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
Apidianakis
Yiorgos
Y
Perrimon
Norbert
N
D000818:Animals; D004330:Drosophila / Q000502:physiology*; D004848:Epithelium / Q000502:physiology*; D006706:Homeostasis; D008322:Mammals / Q000502:physiology*; D012038:Regeneration; D013234:Stem Cells / Q000502:physiology*