Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12.
Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12 is reported in the form of its octyl glycoside. Syntheses of the 1,2-cis glycosidic linkages have been accomplished by using NIS in conjunction with H(2)SO(4)-silica, and it was found to be stereoselective and productive. The synthesized tetrasaccharide will be utilized as the substrate for galactofuranosyltransferase, WbbI.
Roy
Bimalendu
B
Indian Institute of Science Education and Research-Kolkata, Mohanpur Campus, P.O. BCKV Campus Main Office, Mohanpur, Nadia, West Bengal, India.
Field
Robert A
RA
Mukhopadhyay
Balaram
B
D002240:Carbohydrate Sequence; D048168:Escherichia coli K12 / Q000276:immunology*; D019081:O Antigens / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis*
D019081:O Antigens; D009844:Oligosaccharides