title: Recovery following propofol-associated brugada electrocardiogram.
abstract: Brugada syndrome is a genetic disorder associated with an increased risk of sudden cardiac death that has typical electrocardiographic (ECG) patterns. Recently, there have been reports of Brugada ECG patterns seen in critically ill patients who received propofol,(1) and this pattern was associated with a very high imminent mortality. We report a case in which a critically ill patient developed a Brugada ECG pattern following high-dose propofol infusion. Once the ECG pattern was recognized, the propofol was discontinued and the ECG pattern resolved, and the patient was discharged home with no arrhythmic sequelae.
authors.affiliation: Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
authors.forename: Justin B
authors.initials: JB
authors.lastname: Weiner
authors.forename: Elias V
authors.initials: EV
authors.lastname: Haddad
authors.forename: Satish R
authors.initials: SR
authors.lastname: Raj
mesh_terms: D000525:Alprazolam / Q000009:adverse effects; D053840:Brugada Syndrome / Q000139:chemically induced / Q000175:diagnosis*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D015742:Propofol / Q000008:administration & dosage / Q000009:adverse effects*; D014147:Tramadol / Q000009:adverse effects; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006993:Hypnotics and Sedatives; D014147:Tramadol; D015742:Propofol; D000525:Alprazolam