Amplifying different [2]catenanes in an aqueous donor-acceptor dynamic combinatorial library.
Two donor-acceptor [2]catenanes have been synthesized and characterized from a single dynamic combinatorial library in water. One of these catenanes is different from earlier related interlocked molecules in that two donor units stack on each other in an unexpected order. Shifting the equilibrium by choosing the right conditions resulted in a significant increase in the yields of the individual catenanes.
Au-Yeung
Ho Yu
HY
University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Dan Pantoş
G
G
Sanders
Jeremy K M
JK
D043863:Catenanes / Q000138:chemical synthesis*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D008968:Molecular Conformation
D043863:Catenanes