title: [Pediatric Mediterranean spotted fever].
abstract: In France, Mediterranean spotted fever due to Rickettsia conorii is mainly observed in the South-east. Rhipicephalus sanguineus, the brown dog tick, is the vector and the reservoir of the disease. Clinical diagnosis relies on the association of fever, rash and inoculation's scar during summertime. Pathological lesion is a diffuse vasculitis. Severity is often explained by a delay in diagnosis, but prognosis is good in pediatrics. Treatment relies on doxycycline and on macrolids in children under eight.
authors.affiliation: Service de Pédiatrie, CHU Nord, chemin des Bourrelly, 13015 Marseillle. jean-marc.garnier@ap-hm.fr
authors.forename: J-M
authors.initials: JM
authors.lastname: Garnier
authors.forename: A-L
authors.initials: AL
authors.lastname: Jurquet
authors.forename: K
authors.initials: K
authors.lastname: Retornaz
authors.forename: P-E
authors.initials: PE
authors.lastname: Fournier
authors.forename: P
authors.initials: P
authors.lastname: Minodier
mesh_terms: D000818:Animals; D001907:Boutonneuse Fever / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D002648:Child; D004197:Disease Reservoirs; D004285:Dogs / Q000382:microbiology*; D004318:Doxycycline / Q000627:therapeutic use*; D005602:France / Q000453:epidemiology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000627:therapeutic use; D018942:Macrolides / Q000627:therapeutic use; D011379:Prognosis; D020114:Rickettsia conorii / Q000302:isolation & purification*; D015047:Zoonoses / Q000635:transmission
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D018942:Macrolides; D004318:Doxycycline