title: [The time course of changes in cell immunological parameters during administration of live dry plague vaccine].
abstract: The study of the time course of changes in cell immunological parameters by a magnetic separation technique in human beings during the administration of plague vaccine in relation to the immunological load revealed the higher blood levels of all T lymphocyte subpopulations on day 14 after vaccination. These changes are most typical of a primary vaccinated cohort. The increased frequency of plague vaccine administration and multiple immunizations with live plague, anthrax, and tularemia vaccines produce the time-course of changes in T lymphocyte populations (subpopulations) in response to the regular administration of plague vaccine. A high immunological load in man also promotes a significant reduction in the level of B lymphocytes.
authors.forename: N V
authors.initials: NV
authors.lastname: Bogacheva
authors.forename: I V
authors.initials: IV
authors.lastname: Darmov
authors.forename: I V
authors.initials: IV
authors.lastname: Borisevich
authors.forename: A V
authors.initials: AV
authors.lastname: Kriuchkov
authors.forename: D V
authors.initials: DV
authors.lastname: Pechenkin
mesh_terms: D022122:Anthrax Vaccines / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology; D005604:Francisella tularensis / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D010930:Plague / Q000276:immunology / Q000517:prevention & control*; D010931:Plague Vaccine / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D014611:Vaccination; D014613:Vaccines, Attenuated / Q000276:immunology
chemical_list: D022122:Anthrax Vaccines; D001428:Bacterial Vaccines; D010931:Plague Vaccine; D014613:Vaccines, Attenuated