title: Gene-directed enzyme prodrug therapy for cancer: a glimpse into the future?
abstract: Gene-directed enzyme prodrug therapy offers a new approach to treating some cancers. Clinical trials have been completed for brain and prostate cancers and the first product for post-surgical treatment of some brain tumors is awaiting marketing approval. Recent innovations provide a glimpse into the possible future evolution of a new gene medicine.
authors.affiliation: Biotech Equity Partners, North Ryde, NSW, 2113, Australia.
authors.forename: Gerald W
authors.initials: GW
authors.lastname: Both
mesh_terms: D005822:Genetic Vectors / Q000235:genetics; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000628:therapy*; D011355:Prodrugs / Q000378:metabolism*
chemical_list: D011355:Prodrugs