title: Carcinoma ex pleomorphic adenoma in a minor salivary gland: report of a case.
abstract: BACKGROUND
  Carcinoma ex pleomorphic adenoma is exceedingly rare in minor salivary glands of the oral cavity. We present a case of carcinoma ex pleomorphic adenoma (CEPA) of the buccal mucosa in a 47-year-old Turkish patient. The buccal mass was of a size of 1.5 cm located in the left cheek. Pleomorphic adenoma was the tentative diagnosis.
  
  
  METHODS
  The tumor was removed under local anesthesia. Histopathologic evaluation revealed a preexisting pleomorphic adenoma associated with adenoid tumor component with tubulo-cystic and papillary or pseudopapillary structures; CEPA was diagnosed. Capsular integrity was incomplete with infiltration by islands of metaplastic/dysplastic epithelium.
  
  
  RESULTS
  Secondary surgery of the site was performed. No tumor tissue could be detected in the resection specimen. The patient is free of recurrence since 9 months.
authors.affiliation: Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Reichart
authors.forename: Steffen
authors.initials: S
authors.lastname: Kalz
authors.forename: Annette
authors.initials: A
authors.lastname: Rabel
authors.forename: Michael M
authors.initials: MM
authors.lastname: Bornstein
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D002610:Cheek; D006801:Humans; D008046:Lip; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D012086:Reoperation; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D012470:Salivary Glands, Minor / Q000473:pathology* / Q000601:surgery