title: [Epidemiological characteristics and risk factors for apparent life-threatening events].
abstract: BACKGROUND
  To report our experience with a guideline approach for the assessment of apparent life-threatening events (ALTE) in our pediatric emergency departments (PED), to know their incidence, epidemiological characteristics and the yield of laboratory investigations (LI).
  
  
  METHODS
  Prospective, case-control study of a guideline approach for infants under age 12 months who suffered an ALTE between 01/06/06 and 31/05/07 and were attended at our PEDs. We ordered LI as a function of the clinical history. All the cases were admitted for a minimum of 12h. We conducted a telephone interview at 12 months.
  
  
  RESULTS
  Fifty ALTE were included, corresponding to an incidence of 5 per thousand live births. The median age was 8.46+/-8.7 weeks. Compared to controls they had significantly more primogenits and previous behavioral abnormalities. Only 13 presented significant abnormalities at examination, and 6 had recurrent ALTE at the PED. LI were abnormal in 41 (82%), but only in 8 cases did they contribute to a secondary diagnosis. There were 29 idiopathic ALTE (58%). Twenty one (42%) had associated conditions, who had smoked significantly more during pregnancy, age older than 12 weeks and abnormalities at examination. Four had recurrence of the episodes: one suffered a sudden infant death syndrome (SIDS). At 12 months the cases had a significantly higher incidence of recurrent vomiting, breath holding spells and weight-psychomotor retardation.
  
  
  CONCLUSIONS
  The ALTE incidence was 5 per thousand live births. Primogenits and/or behavioral abnormalities were most frequent during the first weeks after birth and/or thereafter at 12 months of age. A total of 42% had a related diagnosis: associated with age older than 12 weeks, maternal smoking habits and abnormalities at examination. There was one case of SIDS. Laboratory investigations had a low yield.
authors.affiliation: Servicio de Urgencias de Pediatría, Hospital de Cruces, Barakaldo, Bizkaia, España. jesus_sanchez_etxaniz@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Sánchez Etxaniz
authors.forename: M
authors.initials: M
authors.lastname: Santiago Burruchaga
authors.forename: A
authors.initials: A
authors.lastname: González Hermosa
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez Serrano
authors.forename: E
authors.initials: E
authors.lastname: Astobiza Beobide
authors.forename: M I
authors.initials: MI
authors.lastname: Vega Martín
mesh_terms: D016022:Case-Control Studies; D004630:Emergencies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors