A fast and oxygen-promoted protocol for the ligand-free Suzuki reaction of 2-halogenated pyridines in aqueous media.
A fast protocol has been developed for the construction of 2-aryl-substituted pyridine derivatives by the oxygen-promoted, ligand-free, Pd(OAc)2-catalyzed Suzuki reaction of 2-halogenated pyridines in aqueous isopropanol.
Liu
Chun
C
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Zhongshan Road 158, 116012, Dalian, China. chunliu70@yahoo.com
Yang
Weibo
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D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
D006846:Hydrocarbons, Halogenated; D011725:Pyridines; C023666:pyridine; D010100:Oxygen