title: NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives.
abstract: The 1H and 13C NMR resonances of 22 5-(5-substituted-2-nitrophenyl)-1H-pyrrole-2-carboxamides, 22 5-(5-substituted-2-aminophenyl)-1H-pyrrole-2-carboxamides, and 9 5-phenyl-1H-pyrrole-2-carboxamides were assigned completely using the concerted application of one- and two-dimensional experiments (DEPT, gs-HMQC and gs-HMBC). NOE studies and conformational analysis confirm the preferred conformations of such compounds.
authors.affiliation: Departamento de Química Farmacéutica y Orgánica, Facultad de Farmacia, Universidad de Granada, 18071 Granada, Spain.
authors.forename: Luisa C
authors.initials: LC
authors.lastname: López-Cara
authors.forename: M José
authors.initials: MJ
authors.lastname: Pineda de las Infantas
authors.forename: M Dora
authors.initials: MD
authors.lastname: Carrión
authors.forename: M Encarnación
authors.initials: ME
authors.lastname: Camacho
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Gallo
authors.forename: Antonio
authors.initials: A
authors.lastname: Espinosa
authors.forename: Antonio
authors.initials: A
authors.lastname: Entrena
mesh_terms: D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011522:Protons; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D012015:Reference Standards; D013237:Stereoisomerism
chemical_list: D002247:Carbon Isotopes; D011522:Protons; D011720:Pyrazoles