title: [Is there an interest in para-aortic lymphadenectomy in operable endometrial cancer?].
abstract: The indication and extent of lymph node dissection in the surgical management of endometrial cancer remains controversial especially concerning the para-aortic lymph nodes. The therapeutic benefit of the lymph node dissection is criticized mainly for low-risk patients for extra-uterine spread. Surgically staging patients is the best method to predict node involvement and it allows an optimal decision for adjuvant therapy to be taken. The different prognostic factors for para-aortic lymph nodes metastasis are histological grade and size of the tumour, myometrial wall invasion and lymphovascular dissemination, as well as positive pelvic lymph nodes. However, these elements are not correctly evaluated before and during the surgery. Positive para-aortic lymph nodes can be found without a lymphatic spread to the pelvic area. Even though the prevalence of para-aortic node involvement is weak, it seems legitimate to propose in selected cases of important lymph node involvement, it's complete dissection if a pelvic lymphadenectomy is indicated and if it is surgically possible.
authors.affiliation: Service de gynécologie, hôpital Lariboisière (AP-HP), 2, rue Ambroise-Paré, 75010 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Bouquier
authors.forename: A
authors.initials: A
authors.lastname: Bricou
authors.forename: Y
authors.initials: Y
authors.lastname: Delpech
authors.forename: L
authors.initials: L
authors.lastname: Tulpin
authors.forename: G
authors.initials: G
authors.lastname: Akerman
authors.forename: E
authors.initials: E
authors.lastname: Barranger
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D001011:Aorta; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects / Q000379:methods; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D010388:Pelvis; D012187:Retroperitoneal Space; D012307:Risk Factors; D021701:Sentinel Lymph Node Biopsy; D047368:Tumor Burden