Influence of environmental enrichment on an object recognition task in CF1 mice.
Environmental enrichment (EE) is an experimental model for studying neuroplasticity. EE is used to investigate behavioral modifications associated with gene-environmental interaction. The object recognition task (ORT) evaluates animals' ability to learn about their environment, which depends on their innate instinct. By using young CF1 mice, the present study evaluated the effect of 8 weeks of EE on the ORT. Our results indicate that EE decreased the time the animals spent exploring familiar and unfamiliar objects and total time spent exploring both objects, without affecting the capacity of discrimination of objects. These findings indicate a more propitious behavior for species survival in animals subjected to EE, including rapid exploration and learning about the environment.
Viola
Giordano Gubert
GG
Departamento de Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90035 003, Brazil. giorgviola@gmail.com
Botton
Paulo Henrique
PH
Moreira
Júlia Dubois
JD
Ardais
Ana Paula
AP
Oses
Jean Pierre
JP
Souza
Diogo Onofre
DO
D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism; D004192:Discrimination, Psychological / Q000502:physiology; D004777:Environment; D005106:Exploratory Behavior / Q000502:physiology; D005786:Gene Expression Regulation / Q000502:physiology; D006624:Hippocampus / Q000378:metabolism; D008297:Male; D051379:Mice; D020813:Receptor, trkB / Q000378:metabolism; D021641:Recognition, Psychology / Q000502:physiology*
D019208:Brain-Derived Neurotrophic Factor; D020813:Receptor, trkB