Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy.
Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this fifth of 6 sections of the guidelines of care for psoriasis, we discuss the use of ultraviolet (UV) light therapy for the treatment of patients with psoriasis. Treatment should be tailored to meet individual patients' needs. We will discuss in detail the efficacy and safety as well as offer recommendations for the use of phototherapy, including narrowband and broadband UVB and photochemotherapy using psoralen plus UVA, alone and in combination with topical and systemic agents. We will also discuss the available data for the use of the excimer laser in the targeted treatment of psoriasis. Finally, where available, we will summarize the available data that compare the safety and efficacy of the different forms of UV light therapy.
Menter
Alan
A
Psoriasis Research Center, Baylor University Medical Center, Dallas, Texas.
Korman
Neil J
NJ
Murdough Family Center for Psoriasis, Department of Dermatology, University Hospitals Case Medical Center, Cleveland, Ohio.
Elmets
Craig A
CA
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama.
Feldman
Steven R
SR
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Gelfand
Joel M
JM
Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania.
Gordon
Kenneth B
KB
Division of Dermatology, Evanston Northwestern Healthcare and Department of Dermatology, Northwestern University, Fienberg School of Medicine, Chicago, Illinois.
Gottlieb
Alice
A
Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts.
Koo
John Y M
JYM
Department of Dermatology, University of California-San Francisco, San Francisco, California.
Lebwohl
Mark
M
Department of Dermatology, Mount Sinai School of Medicine, New York, New York.
Lim
Henry W
HW
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Van Voorhees
Abby S
AS
Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Beutner
Karl R
KR
Anacor Pharmaceuticals, Inc, Palo Alto, California; Department of Dermatology, University of California San Francisco, San Francisco, California.
Bhushan
Reva
R
American Academy of Dermatology, Schaumburg, Illinois. Electronic address: rbhushan@aad.org.
D000328:Adult; D015535:Arthritis, Psoriatic / Q000628:therapy*; D002648:Child; D005260:Female; D006801:Humans; D015603:Keratinocytes / Q000473:pathology; D011701:PUVA Therapy; D010778:Photochemotherapy; D010789:Phototherapy / Q000009:adverse effects / Q000379:methods; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy; D011565:Psoriasis / Q000188:drug therapy / Q000628:therapy*