title: Establishing legitimacy and function in the new transcriptome.
abstract: The last decade has seen an explosion of interest in new classes of non-coding RNA. While some are now firmly established as new categories of legitimate functional RNAs, the purpose and even existence of others remain to be solidified. Here, we discuss the challenges associated with discovery and characterization of non-traditional categories of non-coding RNA.
authors.affiliation: Banting and Best Department of Medical Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
authors.forename: Harm
authors.initials: H
authors.lastname: van Bakel
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Hughes
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling; D006801:Humans; D011401:Promoter Regions, Genetic; D022661:RNA, Untranslated / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D022661:RNA, Untranslated