title: Severe acetaminophen poisoning treated with a fractionated plasma separation and absorption system: A case report.
abstract: Acetaminophen is an analgesic drug that is frequently used in suicide attempts. In this paper, we report on a 17-year-old girl who was admitted to an emergency department 15 hours after taking acetaminophen pills in a suicide attempt. Her serum acetaminophen level was 73 mg/L on admission; she had elevated liver enzymes suggesting hepatic necrosis. She was started on N-acetyl cystein (NAC), and treated successfully with a fractionated plasma separation and absorption system.
authors.affiliation: Cukurova University School of Medicine, Department of Emergency Medicine, Balcali-Adana, Turkey. asebe@cu.edu.tr
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sebe
authors.forename: Salim
authors.initials: S
authors.lastname: Satar
authors.forename: N
authors.initials: N
authors.lastname: Rana Alpay
authors.forename: Mesude
authors.initials: M
authors.lastname: Murt
authors.forename: Birol
authors.initials: B
authors.lastname: Güvenç
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D000111:Acetylcysteine / Q000627:therapeutic use; D000293:Adolescent; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D010956:Plasmapheresis; D011041:Poisoning / Q000188:drug therapy / Q000201:enzymology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000082:Acetaminophen; D000111:Acetylcysteine