A consensus statement on the management of pregnancy and delivery in women who are carriers of or have bleeding disorders.
Pregnancy and delivery are critical times for women with bleeding disorders, with mothers, and possibly their affected infants, being exposed to a variety of haemostatic challenges. Management of women with bleeding disorders during pregnancy involves a multidisciplinary team including, but not limited to, an obstetrician, an anaesthetist and a haematologist. This consensus document from the Australian Haemophilia Centre Directors' Organisation (AHCDO) provides practical information for clinicians managing women with bleeding disorders during pregnancy. Included are: the expected physiological response in pregnancy in such women; management of pregnancy, labour and delivery, as well as obstetric anaesthesia issues, postpartum care, and reducing and treating postpartum haemorrhage; and management of infants at risk of a bleeding disorder and of bleeding in neonates. The guidelines were developed after extensive consultation, face-to-face meetings and revisions. The final document represents a consensus opinion of all AHCDO members. Where evidence is lacking, recommendations are based on clinical experience and consensus opinion.
Dunkley
Scott M
SM
Institute of Haematology, Royal Prince Alfred Hospital, Sydney, NSW, Australia. scott.dunkley@sswahs.nsw.gov.au
Russell
Susan J
SJ
Rowell
John A
JA
Barnes
Chris D
CD
Baker
Ross I
RI
Sarson
Megan I
MI
Street
Alison M
AM
D000773:Anesthesia, Obstetrical / Q000592:standards; D025861:Blood Coagulation Disorders, Inherited / Q000150:complications / Q000628:therapy*; D001779:Blood Coagulation Factors / Q000627:therapeutic use*; D005260:Female; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D010348:Patient Care Team; D006473:Postpartum Hemorrhage / Q000517:prevention & control*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy*
D001779:Blood Coagulation Factors; D006490:Hemostatics