title: Secondary amyloidosis associated with multiple sclerosis.
abstract: BACKGROUND
  Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS.
  
  
  METHODS
  A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS.
  
  
  CONCLUSIONS
  This is the first report of secondary amyloidosis associated with MS.
authors.affiliation: Department of Neurology, Hanyang University College of Medicine, Guri, Korea.
authors.forename: Seok Jae
authors.initials: SJ
authors.lastname: Kang
authors.forename: Joo-Hark
authors.initials: JH
authors.lastname: Yi
authors.forename: Hyun-Seok
authors.initials: HS
authors.lastname: Hong
authors.forename: Si-Hyung
authors.initials: SH
authors.lastname: Jang
authors.forename: Moon-Hyang
authors.initials: MH
authors.lastname: Park
authors.forename: Ho-Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Lee
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Sang-Woong
authors.initials: SW
authors.lastname: Han
authors.forename: Seong-Ho
authors.initials: SH
authors.lastname: Koh