[Hypokalemic paralysis revealing Sjögren's syndrome associated with auto-immune thyroiditis].
We report a case of 36-year-old woman, admitted for hypotonic tetraparesis. Laboratory tests revealed severe hypokalaemia, acidosis, hyperchloremia and alkaline urinary pH allowing the diagnosis of distal tubular acidosis. Additional investigations led to the diagnosis of primary Sjögren's syndrome associated with Hashimoto's thyroïditis. The evolution was favorable under potassium citrate alkalinisation, the corticosteroid therapy and hormonal substitution. Based on this observation, the pathogenesis of distal tubular acidosis during auto-immune diseases (Sjögren's syndrome, monoclonal hypergammaglobulinemia, hypothyroidism) was discussed as well as its consequences and management.
Baaj
Mohamed
M
Service de médecine interne, hôpital militaire Moulay Ismaïl, Meknès, Maroc.
Safi
Somaya
S
Hassikou
Hassna
H
Tabache
Fatima
F
Mouden
Karim
K
Hadri
Larbi
L
D000328:Adult; D005260:Female; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013967:Thyroiditis, Autoimmune / Q000150:complications*