Celiac disease, Behçet, and idiopathic thrombocytopenic purpura in siblings of a patient with multiple sclerosis.
Multiple sclerosis (MS) is a demyelinating disease of uncertain etiology. Many genetic and environmental risk factors have been associated with this disease including certain human leukocyte antigen haplotypes, Epstein-Barr virus infection, and vitamin D deficiency. We report a 30-year-old woman with MS, the product of consanguineous marriage, and three siblings with three different autoimmune diseases: idiopathic thrombocytopenic purpura, celiac disease, and Behçet's disease.
Yamout
Bassem
B
Department of Internal Medicine, American University of Beirut, Medical Center, Beirut, Lebanon.
Usta
Jinan
J
Itani
Salam
S
Yaghi
Shadi
S
D000328:Adult; D001327:Autoimmune Diseases / Q000235:genetics; D001528:Behcet Syndrome / Q000235:genetics*; D001921:Brain / Q000473:pathology; D002446:Celiac Disease / Q000235:genetics*; D003241:Consanguinity; D003711:Demyelinating Diseases / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000235:genetics*; D010375:Pedigree; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000235:genetics*; D035781:Siblings