Suzuki-Miyaura coupling reactions in aqueous microdroplets with catalytically active fluorous interfaces.
Using microfluidic techniques and a novel fluorous-tagged palladium catalyst, we generated droplet reactors with catalytically active walls and used these compartments for small molecule synthesis.
Theberge
Ashleigh B
AB
Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW. abt30@cam.ac.uk
Whyte
Graeme
G
Frenzel
Max
M
Fidalgo
Luis M
LM
Wootton
Robert C R
RC
Huck
Wilhelm T S
WT
D002384:Catalysis; D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D010165:Palladium / Q000737:chemistry*; D054852:Small Molecule Libraries / Q000138:chemical synthesis*
D054852:Small Molecule Libraries; D010165:Palladium