Trends in the epidemiology of human G1P[8] rotaviruses: a hungarian study.
Epidemiological trends of the globally most common rotavirus genotype, G1P[8], were investigated in Hungary during a 16-year period by sequencing and phylogenetic analysis of the surface antigens. Antigen shift among epidemiologically major G1P[8] strains was observed in 6 seasons, as indicated by changes in the sublineages of the G1 VP7 and the P[8] VP4 genes. The temporal clustering of some rotavirus VP4 and VP7 gene sublineages and the periodic emergence and/or resurgence of previously unrecognized rotavirus sublineages in the study population suggest a dynamic nature for these common strains. Recently established international strain surveillance networks may help to identify and track the spread of epidemiologically important rotavirus strains across countries and continents.
Bányai
Krisztián
K
Regional Laboratory of Virology, Baranya County Institute of State Public Health Service, Hungarian Academy of Sciences, Budapest, Hungary. bkrota@hotmail.com
Gentsch
Jon R
JR
Martella
Vito
V
Bogdán
Agnes
A
Havasi
Viktória
V
Kisfali
Péter
P
Szabó
Alíz
A
Mihály
Ilona
I
Molnár
Péter
P
Melegh
Béla
B
Szücs
György
G
D019943:Amino Acid Substitution; D000956:Antigens, Viral / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D012401:Rotavirus / Q000145:classification / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology; D013997:Time Factors
D000956:Antigens, Viral; D036022:Capsid Proteins; C060339:VP4 protein, Rotavirus; C050779:VP7 protein, Rotavirus