[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?].
The occurrence of metabolic syndrome (MS) and osteoporosis is essentials danger for public health. It seems that one of epidemiological factors of those diseases is age-depending adrenal androgens deficiency.


OBJECTIVE
was to evaluate relationships between DHEA/DHEAS serum levels and BMD along with frequency of MS in ageing Caucasian men.


METHODS
In 271 randomly chosen men aged 40 to 80 years living in Lubuskie district (Poland) adrenal androgens, anthropometrical indices in addition to densitometry were estimated.


RESULTS
DHEA/DHEAS serum levels showed positive correlation with BMD (r = 0.16 and r = 0.18, respectively, p < 0.001). Statistic essential dependencies between decreased adrenal androgens and coexistence of neoplastic diseases (p < 0.001), hypertension (p < 0.05), peripheral perfusion disturbances (p < 0.005) and dementia (p < 0.0001) were also observed.


CONCLUSIONS
The evaluation of DHEA/DHEAS serum level is useful in estimation of general health status of ageing men, but does not identify participants suffering from metabolic syndrome.
Herman
Waldemar Adam
WA
HERMED Out-Patient Clinic in Wschowa, Poland. wherman@wschowa.com.pl
Seńko
Aleksandra
A
Korczowska
Izabela
I
Łacka
Katarzyna
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D015897:Comorbidity; D003687:Dehydroepiandrosterone / Q000097:blood*; D003704:Dementia / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D054526:Men's Health; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology; D010024:Osteoporosis / Q000097:blood* / Q000453:epidemiology; D012307:Risk Factors
D003687:Dehydroepiandrosterone