[Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery].
Radionecrosis with brain edema is a complication of radiosurgery. Three female patients harbouring a frontal pole, petrous and parasagital parietoocipital meningiomas respectively who had been treated with LINAC radiosurgery are presented. Those patients developed, between two and eight months later, a severe symptomatic radionecrosis with a huge brain edema resistant to the usual steroid therapy. Only after 40 sessions of hyperbaric oxygen, a good remission of the lesions was obtained. There are few cases reported in the literature with such a good outcome. Consequentely, this therapy must be taken into account to treat this type of radiosurgical complication before considering surgery.
Pérez-Espejo
M A
MA
Servicios de Neurocirugía. Hospital Universitario "Virgen Arrixaca". Murcia. España.
García-Fernández
R
R
Tobarra-González
B M
BM
Palma-Copete
J D
JD
González-López
A
A
De la Fuente-Muñoz
I
I
Salinas-Ramos
J
J
Felipe-Murcia
M
M
Martínez-Lage
J F
JF
Fernández-Pérez
J
J
Romero
J M
JM
D000368:Aged; D001925:Brain Damage, Chronic / Q000209:etiology / Q000517:prevention & control; D001929:Brain Edema / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D001930:Brain Injuries / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D002528:Cerebellar Neoplasms / Q000601:surgery; D002530:Cerebellopontine Angle / Q000473:pathology / Q000528:radiation effects; D004730:Endothelium, Vascular / Q000473:pathology / Q000528:radiation effects; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000601:surgery; D008579:Meningioma / Q000601:surgery; D008875:Middle Aged; D009336:Necrosis; D010296:Parietal Lobe / Q000473:pathology / Q000528:radiation effects; D011832:Radiation Injuries / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D016634:Radiosurgery / Q000009:adverse effects*; D016896:Treatment Outcome