title: Predictors of adherence to cognitive-behavioural therapy in first-episode psychosis.
abstract: OBJECTIVE
  To investigate predictors of adherence with a cognitive-behavioural intervention in first-episode psychosis (FEP) patients.
  
  
  METHODS
  Predictors of adherence to cognitive-behavioural therapy (CBT) were longitudinally investigated in the experimental arm of a randomized controlled trial designed to evaluate the effectiveness of a CBT intervention for relapse prevention early in the course of psychosis when compared with treatment as usual within 2 high quality, youth oriented, specialist FEP programs (the EPISODE II trial).
  
  
  RESULTS
  Longer duration of untreated psychosis (DUP) and poorer level of insight predicted poor adherence to CBT. This association remained significant after controlling for potential confounders.
  
  
  CONCLUSIONS
  Treatment delay may decrease adherence with CBT in FEP patients. Reducing DUP and promoting insight early in the course of psychosis are likely to enhance adherence with CBT.
authors.affiliation: ORYGEN Youth Health Research Centre, Melbourne, Victoria, Australia. malvarez@unimelb.edu.au
authors.forename: Mario
authors.initials: M
authors.lastname: Alvarez-Jiménez
authors.forename: John F
authors.initials: JF
authors.lastname: Gleeson
authors.forename: Sue
authors.initials: S
authors.lastname: Cotton
authors.forename: Darryl
authors.initials: D
authors.lastname: Wade
authors.forename: Donna
authors.initials: D
authors.lastname: Gee
authors.forename: Tracey
authors.initials: T
authors.lastname: Pearce
authors.forename: Kingsley
authors.initials: K
authors.lastname: Crisp
authors.forename: Daniela
authors.initials: D
authors.lastname: Spiliotacopoulos
authors.forename: Belinda
authors.initials: B
authors.lastname: Newman
authors.forename: Patrick D
authors.initials: PD
authors.lastname: McGorry
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001364:Awareness; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D005196:Family Therapy; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010349:Patient Compliance / Q000523:psychology*; D011379:Prognosis; D011446:Prospective Studies; D011618:Psychotic Disorders / Q000523:psychology / Q000628:therapy*; D055502:Secondary Prevention; D016037:Single-Blind Method; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents