[Apelin--a new protein-regulator in the cardiovascular system].
Apelin is an endogenic ligand of apelin (APJ) receptors widely expressed in human tissues. This protein is a peripheral vasodilator having a powerful positive inotropic action on myocardial contractility. This review describes mechanisms of interaction and apelin role in health and pathology.
Tereshchenko
S N
SN
Masenko
V P
VP
Cherkavskaia
O V
OV
Shashkova
N V
NV
D000804:Angiotensin II / Q000378:metabolism*; D000818:Animals; D000073861:Apelin; D000075244:Apelin Receptors; D002318:Cardiovascular Diseases / Q000378:metabolism*; D002319:Cardiovascular System / Q000378:metabolism*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics / Q000378:metabolism*
C115436:APLN protein, human; C104575:APLNR protein, human; D000073861:Apelin; D000075244:Apelin Receptors; D036341:Intercellular Signaling Peptides and Proteins; D043562:Receptors, G-Protein-Coupled; D000804:Angiotensin II