title: Bilayers coating on titanium surface: the impact on the hydroxyapatite initiation.
abstract: Most of the actual orthopaedic devices, widely made of titanium and its alloys, present different weaknesses like ions release and risks of loosening over a long period. To solve such problems, new developments in surface modification are crucial. This work is an extension of our recent effort on the development and improvement of a multifunctional inorganic/organic bilayers coating. A thin tantalum oxide layer is formed by sol-gel synthesis followed by the modification with organophosphonic acids of the tantalum oxide layer. We focus in particular on the effect of the bilayers coating on corrosion resistance and hydroxyapatite growth rate by immersion in a simulated body fluid solution. It is also highlighted that the structure of the organophosphonic acid is of major importance on the osteoinduction character of the material.
authors.affiliation: Laboratory of Chemistry and Electrochemistry of Surfaces, University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium.
authors.forename: Christelle
authors.initials: C
authors.lastname: Arnould
authors.forename: Jessica
authors.initials: J
authors.lastname: Denayer
authors.forename: Michael
authors.initials: M
authors.lastname: Planckaert
authors.forename: Joseph
authors.initials: J
authors.lastname: Delhalle
authors.forename: Zineb
authors.initials: Z
authors.lastname: Mekhalif
mesh_terms: D017886:Durapatite / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D063065:Organophosphonates / Q000737:chemistry; D010087:Oxides / Q000737:chemistry*; D013499:Surface Properties; D013635:Tantalum / Q000737:chemistry*
chemical_list: D063065:Organophosphonates; D010087:Oxides; D013635:Tantalum; D017886:Durapatite; C078151:tantalum oxide