title: Laparoscopic surgery for pelvic pain associated with endometriosis.
abstract: BACKGROUND
  Endometriosis is the presence of endometrial glands or stroma in sites other than the uterine cavity. It is variable in both its surgical appearance and clinical manifestation often with poor correlation between the two. Surgical treatment of endometriosis aims to remove visible areas of endometriosis and restore anatomy by division of adhesions and relieve painful symptoms.
  
  
  OBJECTIVE
  To assess the efficacy of laparoscopic surgery in the treatment of pelvic pain associated with endometriosis.
  
  
  METHODS
  For the update in July 2009 we searched the Cochrane Menstrual Disorders and Subfertility Group's specialised register of trials (searched July 2009), the Cochrane Controlled Trials Register (The Cochrane Library, Issue 2, 2009), MEDLINE (1966 July 2009), EMBASE (1980 July 2009), and reference lists of articles.
  
  
  METHODS
  Randomised controlled trials were selected comparing the effectiveness of laparoscopic surgery used to treat pelvic pain associated with endometriosis, with other treatment modalities or diagnostic laparoscopy only.
  
  
  METHODS
  Assessment of trial quality and extraction of relevant data was performed independently by two reviewers.
  
  
  RESULTS
  Five studies were included in the meta-analysis, including three full papers and two conference reports. All the randomised controlled trials with the exception of Lalchandani 2003 compared different laparoscopic surgical techniques with diagnotic laparoscopy only. Lalchandani 2003 compared laparoscopic coagulation therapy with diagnostic laparoscopy and medical treatment. Three studies (Abbott 2004; Sutton 1994; Tutunaru 2006) reported the pain scores six months post operatively. Meta-analysis demonstrated an advantage of laparoscopic surgery when compared to diagnostic laparoscopy only (OR of 5.72 95%Cl 3.09 to 10.60 ; 171 participants, three trials, Analysis 1.1). A single study (Tutunaru 2006) reported pain scores twelve months after the procedure. Analysis demonstrated an advantage of laparoscopic surgery when compared to diagnostic laparoscopy only (OR of 7.72 95%Cl 2.97 to 20.06 ; 33 participants, one trial, Analysis 1.1).
  
  
  CONCLUSIONS
  Laparoscopic surgery results in improved pain outcomes when compared to diagnostic laparoscopy alone. There were few women diagnosed with severe endometriosis included in the meta-analysis and therefore any conclusions from this meta-analysis regarding treatment of severe endometriosis should be made with caution. It is not possible to draw conclusions from the meta-analysis which specific laparoscopic surgical intervention is most effective.
authors.affiliation: Department of Obstetrics and Gynaecology, South Auckland Clinical School, Middlemore Hospital, Private Bag 93311, Auckland, New Zealand.
authors.forename: Tal Z
authors.initials: TZ
authors.lastname: Jacobson
authors.forename: James M N
authors.initials: JM
authors.lastname: Duffy
authors.forename: David
authors.initials: D
authors.lastname: Barlow
authors.forename: Philippe R
authors.initials: PR
authors.lastname: Koninckx
authors.forename: Ray
authors.initials: R
authors.lastname: Garry
mesh_terms: D004715:Endometriosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D053685:Laser Therapy; D017699:Pelvic Pain / Q000209:etiology / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic; D000267:Tissue Adhesions / Q000601:surgery