Treatment of tardive dyskinesia with aripiprazole.
Tardive dyskinesia (TD) is a severe and potential irreversible side effect of antipsychotic treatment. Treatment of established TD is often unsuccessful. In this article, we report three cases of psychogeriatric patients who suffered from TD as a side effect of long-term treatment with haloperidol that resolved after switching treatment to aripiprazole. Potential psychopharmacological mechanisms explaining this finding are briefly discussed.
Osorio
Ricardo S
RS
Multidisciplinary Support Unit, Alzheimer's Disease Research Unit, Reina Sofia & CIEN Foundations, Carlos III Institute of Health, Unidad de Investigacion Proyecto Alzheimer, Fundacion Reina Sofia-Fundacion CIEN, c/Valderrebollo 5, Madrid, Spain. rosorio@fundacioncien.es
Agüera-Ortiz
L
L
Hurtado de Mendoza
A
A
Ramos
I
I
Palomo
T
T
D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000068180:Aripiprazole; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000188:drug therapy; D010879:Piperazines / Q000627:therapeutic use*; D015363:Quinolones / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D010879:Piperazines; D015363:Quinolones; D000068180:Aripiprazole