title: A new concept in the topical treatment of onychomycosis with cyanoacrylate, undecylenic acid, and hydroquinone.
abstract: The authors report a pilot study of a new approach for the topical treatment of onychomycosis using physiologic principles of fungal growth and serial debridement. In total, 154 patients were studied for 1 year with mild, moderate, and severe nail disease. Negative mycologic cultures in these 3 groups were 100%, 65%, and 35%, respectively. All patients reported subjective improvement in the first 3 months.
authors.affiliation: paulrehdergc65@aol.com
authors.forename: Paul
authors.initials: P
authors.lastname: Rehder
authors.forename: Tim T
authors.initials: TT
authors.lastname: Nguyen
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000008:administration & dosage*; D002648:Child; D003487:Cyanoacrylates / Q000008:administration & dosage*; D003646:Debridement; D004359:Drug Therapy, Combination; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy*; D006801:Humans; D006873:Hydroquinones / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D014009:Onychomycosis / Q000188:drug therapy*; D016896:Treatment Outcome; D014476:Undecylenic Acids / Q000008:administration & dosage*; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D003487:Cyanoacrylates; D006873:Hydroquinones; D014476:Undecylenic Acids; C031927:hydroquinone