title: Allergy to nickel: first results on patients administered with an oral hyposensitization therapy.
abstract: Nickel sulphate allergy is the most common contact allergy. In fact, nickel sulphate is an ubiquitous element, contained in various objects and food; it occurs in igneous rocks, as a free metal and together with iron, but it is also a component of living organism, mainly vegetables. We carried out a clinical trial of oral hyposensitization therapy with low doses of nickel in a group of 67 patients affected by systemic allergy to this sensitizer element. We obtained good results on consequent tolerance to nickel in treated patients.
authors.forename: A
authors.initials: A
authors.lastname: Tammaro
authors.forename: G
authors.initials: G
authors.lastname: De Marco
authors.forename: S
authors.initials: S
authors.lastname: Persechino
authors.forename: A
authors.initials: A
authors.lastname: Narcisi
authors.forename: G
authors.initials: G
authors.lastname: Camplone
mesh_terms: D000284:Administration, Oral; D000485:Allergens / Q000008:administration & dosage*; D017449:Dermatitis, Allergic Contact / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D003888:Desensitization, Immunologic; D004334:Drug Administration Schedule; D006801:Humans; D007108:Immune Tolerance; D007428:Intradermal Tests; D009532:Nickel / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D000485:Allergens; C029938:nickel sulfate; D009532:Nickel