title: Choroidal metastases from lung adenocarcinoma.
abstract: A 32-year-old woman presented with an unknown visual deficit. Fundus examination revealed a lesion compatible with a metastatic focus. Diagnostic workup revealed a lung mass and the biopsy was compatible with lung adenocarcinoma. The intraocular lesion was the only metastatic site at the time of diagnosis. She received local choroidal treatment and further systemic therapy. A pneumonectomy was performed. Five months later she progressed systemically and has since then received several lines of chemotherapy. Choroidal metastases are an infrequent site of systemic dissemination and associated with a poor prognosis, with a median survival of around 2 months if it is the first manifestation of a lung neoplasm. Here we review the literature on choroidal metastases, their treatment options and epidemiology.
authors.affiliation: Department of Hematology and Medical Oncology, Hospital Clínico Universitario, Valencia, Spain. paloma_martin@comv.es
authors.forename: Paloma
authors.initials: P
authors.lastname: Martín Martorell
authors.forename: José F
authors.initials: JF
authors.lastname: Marí Cotino
authors.forename: Amelia
authors.initials: A
authors.lastname: Insa
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents