title: [Hyperbaric oxygenation: utility in intensive therapy - part 2].
abstract: Gangrene, non-clostridial myonecroses and intracranial abscesses are clinical entities for which hyperbaric oxygenation can be used therapeutically. Mortality and invalidity can be reduced by this means. Except for gangrene, HBO is used merely as an adjuvant for these diseases when conventional surgical, antibiotic and intensive therapy measures are not sufficient. The action of HBO is based on several points of attack: it reduces the formation of oedema, inhibits the production of alpha-toxins of the Clostridia, has a bacteriotoxic action, increases the effectivity of antibiotics and improves the immune defense system. An early start is decisive for the success of HBO therapy.
authors.affiliation: Anästhesiologie und Intensivmedizin am Bundeswehrkrankenhaus Ulm.
authors.forename: Lorenz
authors.initials: L
authors.lastname: Lampl
authors.forename: Günter
authors.initials: G
authors.lastname: Frey
authors.forename: Dietmar
authors.initials: D
authors.lastname: Fischer
authors.forename: Silke
authors.initials: S
authors.lastname: Fischer
mesh_terms: D001922:Brain Abscess / Q000382:microbiology / Q000628:therapy; D003015:Clostridium Infections / Q000188:drug therapy / Q000382:microbiology; D003422:Critical Care / Q000379:methods*; D005738:Gas Gangrene / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans; D006931:Hyperbaric Oxygenation