Organocatalytic aziridine synthesis using F+ salts.
This paper describes a unique application of the fluoronium cation (F+) as an organocatalyst for mediating the reaction between N-substituted imines and ethyl diazoacetate affording excellent yields of N-substituted aziridines.
Bew
Sean P
SP
School of Chemistry, University of East Anglia, Norwich, UK. s.bew@uea.ac.uk
Ashford
Polly-Anna
PA
Fairhurst
Shirley A
SA
Hughes
David L
DL
Legentil
Laurent
L
Liddle
John
J
Pesce
Paolo
P
Nigudkar
Sanket
S
Wilson
Martin A
MA
D000085:Acetates / Q000737:chemistry; D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002412:Cations / Q000737:chemistry; D005461:Fluorine / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D009930:Organic Chemicals / Q000737:chemistry*; D012492:Salts / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D000085:Acetates; D001388:Aziridines; D002412:Cations; D007097:Imines; D009930:Organic Chemicals; D012492:Salts; D005461:Fluorine; C033132:aziridine