Mobilization of PML/RARalpha negative peripheral blood stem cells with a combination of G-CSF and CXCR4 blockade in relapsed acute promyelocytic leukemia pre-treated with arsenic trioxide.
Stölzel
Friedrich
F
Wermke
Martin
M
Röllig
Christoph
C
Thiede
Christian
C
Platzbecker
Uwe
U
Bornhäuser
Martin
M
D000328:Adult; D000077237:Arsenic Trioxide; D001152:Arsenicals / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000037:antagonists & inhibitors; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000235:genetics / Q000517:prevention & control / Q000628:therapy*; D009687:Nuclear Proteins / Q000235:genetics; D010087:Oxides / Q000627:therapeutic use*; D036102:Peripheral Blood Stem Cell Transplantation / Q000379:methods*; D000071156:Promyelocytic Leukemia Protein; D019718:Receptors, CXCR4 / Q000037:antagonists & inhibitors; D018168:Receptors, Retinoic Acid / Q000235:genetics; D000072482:Retinoic Acid Receptor alpha; D055502:Secondary Prevention; D014157:Transcription Factors / Q000235:genetics; D025521:Tumor Suppressor Proteins / Q000235:genetics
D001152:Arsenicals; C527276:CXCR4 protein, human; D009687:Nuclear Proteins; D010087:Oxides; D000071156:Promyelocytic Leukemia Protein; C000607071:RARA protein, human; D019718:Receptors, CXCR4; D018168:Receptors, Retinoic Acid; D000072482:Retinoic Acid Receptor alpha; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; D016179:Granulocyte Colony-Stimulating Factor; C070576:PML protein, human; D000077237:Arsenic Trioxide