Fetal cardiac troponin T as a marker of poor prognosis in nonimmune hydrops fetalis.
OBJECTIVE
Severe fetal anemia and cardiac compromise are important causes of nonimmune hydrops fetalis, and fetal recovery also depends on the degree of fetal heart compromise. The aim of this study was to report the fetal cardiac troponin T (cTnT) levels in cases of nonimmune fetal hydrops.


METHODS
Fetal cTnT was analyzed on 7 occasions in 5 cases of nonimmune fetal hydrops (twice in 2 cases).


RESULTS
In 3 of 4 fetuses in which intrauterine death occurred, fetal cTnT levels were increased. The only fetus that survived in this series showed decreased levels of cTnT before birth.


CONCLUSIONS
Fetal cTnT levels may be a marker of fetal prognosis in cases of fetal hydrops.
Nomura
Roseli Mieko Yamamoto
RM
Department of Obstetrics and Gynecology, São Paulo University Medical School, São Paulo, Brazil. roseli.nomura@terra.com.br
Brizot
Maria de Lourdes
Mde L
Liao
Adolfo Wenjaw
AW
Andrade
Joelma Queiroz
JQ
Zugaib
Marcelo
M
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D017218:Cordocentesis; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D011247:Pregnancy; D011379:Prognosis; D020107:Troponin T / Q000097:blood*; D014463:Ultrasonography
D015415:Biomarkers; D020107:Troponin T