title: Cytotoxic activity of a flavanone from the stem of Bauhinia variegata Linn.
abstract: A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representing leukaemia, non-small cell lung, colon, central nervous system, melanoma, ovarian, renal, prostate and breast cancers. The results showed that the flavanone has cytotoxic activity against human tumour cell lines.
authors.affiliation: Department of Pharmacology, St. John's Pharmacy College, Bangalore, India. rajkapoorb1975@yahoo.com
authors.forename: Balasubramanian
authors.initials: B
authors.lastname: Rajkapoor
authors.forename: Narayanan
authors.initials: N
authors.lastname: Murugesh
authors.forename: Devarakonda
authors.initials: D
authors.lastname: Rama Krishna
mesh_terms: D036481:Bauhinia / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D044950:Flavanones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D044950:Flavanones; C028610:flavanone