title: Consistent recovery of sensory stimuli encoded with MIMO neural circuits.
abstract: We consider the problem of reconstructing finite energy stimuli encoded with a population of spiking leaky integrate-and-fire neurons. The reconstructed signal satisfies a consistency condition: when passed through the same neuron, it triggers the same spike train as the original stimulus. The recovered stimulus has to also minimize a quadratic smoothness optimality criterion. We formulate the reconstruction as a spline interpolation problem for scalar as well as vector valued stimuli and show that the recovery has a unique solution. We provide explicit reconstruction algorithms for stimuli encoded with single as well as a population of integrate-and-fire neurons. We demonstrate how our reconstruction algorithms can be applied to stimuli encoded with ON-OFF neural circuits with feedback. Finally, we extend the formalism to multi-input multi-output neural circuits and demonstrate that vector-valued finite energy signals can be efficiently encoded by a neural population provided that its size is beyond a threshold value. Examples are given that demonstrate the potential applications of our methodology to systems neuroscience and neuromorphic engineering.
authors.affiliation: Department of Electrical Engineering, Columbia University, New York, NY 10027, USA. aurel@ee.columbia.edu
authors.forename: Aurel A
authors.initials: AA
authors.lastname: Lazar
authors.forename: Eftychios A
authors.initials: EA
authors.lastname: Pnevmatikakis
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000465:Algorithms; D000818:Animals; D004594:Electrophysiology; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology*