title: Chemical injuries of the oesophagus: aetiopathological issues in Nigeria.
abstract: BACKGROUND
  Chemical injuries of the oesophagus occur worldwide. There is paucity of information on aetiopathological profile of chemical injuries of the oesophagus in Nigeria.
  
  
  OBJECTIVE
  The aim of the study was to determine the aetiopathological pattern of chemical injuries of the oesophagus in Nigeria.
  
  
  METHODS
  This is a multi-centre hospital based study in Lagos metropolis spanning a period of 10 years.The patients' bio data, substances ingested, sources of corrosives, reasons for ingesting corrosives and patients' mental state were recorded.
  
  
  RESULTS
  In all, there were 78 patients (61 Males, 17 Females). The offending agents were acids in 55.1% of cases and it was accidental ingestion in 62 patients. The highest incidence of 57.6% was found in the middle 1/3 of the oesophagus.
  
  
  CONCLUSIONS
  Accidental ingestion of acids is the commonest cause of oesophageal injuries in Nigeria. The incidence of severe strictures necessitating oesophageal substitution could be reduced if early management of corrosive oesophagitis improves in Nigeria.
authors.affiliation: Lagos University Teaching Hospital/College of Medicine of University of Lagos, Nigeria. oluwafemithomas@yahoo.com
authors.forename: Martins O
authors.initials: MO
authors.lastname: Thomas
authors.forename: Ezekiel O
authors.initials: EO
authors.lastname: Ogunleye
authors.forename: Oladapo
authors.initials: O
authors.lastname: Somefun
mesh_terms: D000143:Acids / Q000633:toxicity; D000293:Adolescent; D000328:Adult; D000468:Alkalies / Q000633:toxicity; D002057:Burns, Chemical / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D002424:Caustics / Q000633:toxicity*; D004947:Esophagus / Q000293:injuries*; D005260:Female; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000143:Acids; D000468:Alkalies; D002424:Caustics