title: Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis.
abstract: Chikungunya virus (CHIKV) causes an acute symptomatic illness with fever, skin rash (hypersensitivity vasculitis), incapacitating arthralgia which can evolve to chronic arthritis in elderly patients. Clinical observations from cohort studies have been corroborated with data from experimental infection in several mouse and non-human primate models as discussed herein.
authors.affiliation: Infection Research Grouping, University of la Réunion, St Denis, Ile de la Réunion.
authors.forename: Marie Christine
authors.initials: MC
authors.lastname: Jaffar-Bandjee
authors.forename: Trina
authors.initials: T
authors.lastname: Das
authors.forename: Jean Jacques
authors.initials: JJ
authors.lastname: Hoarau
authors.forename: Pascale
authors.initials: P
authors.lastname: Krejbich Trotot
authors.forename: Mélanie
authors.initials: M
authors.lastname: Denizot
authors.forename: Anne
authors.initials: A
authors.lastname: Ribera
authors.forename: Pierre
authors.initials: P
authors.lastname: Roques
authors.forename: Philippe
authors.initials: P
authors.lastname: Gasque
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018354:Alphavirus Infections / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D000818:Animals; D001168:Arthritis / Q000821:virology*; D002646:Chikungunya virus / Q000472:pathogenicity*; D004195:Disease Models, Animal; D006801:Humans; D007231:Infant, Newborn; D051379:Mice