Potential indications for ovarian autotransplantation based on the analysis of 5,571 autopsy findings of females under the age of 40 in Japan.
Ovarian cryopreservation and autotransplantation could be of potential value for preservation of fertility in the patients with various malignancies. Ovarian tissue should be cryopreserved actively for fertility preservation, but stored tissue should be autotransplanted with much caution until reliable methods are established to detect minimal residual disease in grafts in precise and reproducible manners.
Kyono
Koichi
K
Kyono ART Clinic, Miyagi, Japan. rec-sec@ivf-kyono.or.jp
Doshida
Masakazu
M
Toya
Mayumi
M
Sato
Yuri
Y
Akahira
Junichi
J
Sasano
Hironobu
H
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001344:Autopsy / Q000706:statistics & numerical data; D002648:Child; D003933:Diagnosis; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000473:pathology / Q000628:therapy; D007564:Japan; D008223:Lymphoma / Q000453:epidemiology / Q000473:pathology; D009369:Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000534:rehabilitation; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000556:secondary; D010053:Ovary / Q000473:pathology* / Q000637:transplantation*; D014182:Transplantation, Autologous / Q000706:statistics & numerical data*; D055815:Young Adult