Coronary flow velocity reserve and aortic distensibility indices in hypertensive patients with hypercholesterolaemia and normal epicardial coronary arteries.
The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 1(8) high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 + or - 0.75 vs. 1.97 + or - 0.60, p < 0.05), increased aortic elastic modulus (in 10(3) mmHg) (0.56 + or - 0.41 vs. 0.77 + or - 0.29, p < 0.05) and Young's modulus (in 10(3) mmHg) (5.42 + or - 4.03 vs. 8.57 + or - 4.79, p < 0.05) were found in hypercholesterolaemia.
Nemes
Attila
A
2nd Department of Medicine and Cardiology Center, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.
Forster
Tamás
T
Csanády
Miklós
M
D000328:Adult; D000368:Aged; D001011:Aorta / Q000473:pathology / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D002784:Cholesterol / Q000097:blood; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006973:Hypertension / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010496:Pericardium; D012039:Regional Blood Flow / Q000502:physiology; D013312:Stress, Physiological / Q000502:physiology
D002784:Cholesterol