Simultaneous glycoproteomics on the basis of structure using ion mobility-mass spectrometry.
Simultaneous glycoproteomic characterization using rapid (mus to ms) structural separations provided by ion mobility-mass spectrometry (IM-MS) is described. Advantages from using both ESI and MALDI ion sources are presented with future implications toward high throughput glycan and glycoconjugate characterization.
Fenn
Larissa S
LS
Department of Chemistry, Vanderbilt Institute of Chemical Biology, Vanderbilt Institute of Integrative Biosystems Research and Education, Vanderbilt University, 7330 Stevenson Center, Nashville, TN 37235, USA.
McLean
John A
JA
D006023:Glycoproteins / Q000737:chemistry* / Q000378:metabolism*; D013058:Mass Spectrometry / Q000379:methods*; D008962:Models, Theoretical; D040901:Proteomics / Q000379:methods*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods
D006023:Glycoproteins