title: Disinfection by-products from halogenation of aqueous solutions of terpenoids.
abstract: We report the formation of trihalomethanes and other disinfection by-products from four polyfunctional terpenoids during simulated chlorination of natural waters. Complex suites of products were identified by closed loop stripping analysis (CLSA)/gas chromatography-mass spectrometry (GC-MS) from halogenation of beta-carotene and retinol. beta-Ionone appeared to be a key intermediate in the halogenation of beta-carotene and retinol, reacting further under the reaction conditions to produce trans-beta-ionone-5,6-epoxide and beta-cyclocitral. Halogenation of the four terpenoids also produced trihalomethanes (THMs), most likely through haloform reaction on methyl ketone groups within many of the intermediates. Since halogenation of retinol produced a significant quantity of THMs at a slow reaction rate, retinol-based structures may possibly contribute to the slow reacting phase of THM formation in natural waters. Two polyhydroxyphenol model compounds were halogenated for comparison. The only products identified by CLSA/GC-MS from halogenation of 4',5,7-trihydroxyflavanone and ellagic acid were THMs. 4',5,7-Trihydroxyflavanone rapidly produced THMs, with an extremely high molar yield (94%) at pH 7. Terpenoids of the beta-ionone and retinol type should be considered to be significant THM precursors, while 4',5,7-trihydroxyflavanone has been shown to be an extremely significant THM precursor, potentially present within natural organic matter in water treatment processes and distribution systems.
authors.affiliation: Curtin Water Quality Research Centre, Department of Applied Chemistry, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia. C.Joll@curtin.edu.au
authors.forename: Cynthia A
authors.initials: CA
authors.lastname: Joll
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Alessandrino
authors.forename: Anna
authors.initials: A
authors.lastname: Heitz
mesh_terms: D004203:Disinfection; D054879:Halogenation; D013729:Terpenes / Q000032:analysis / Q000737:chemistry*; D022882:Trihalomethanes / Q000032:analysis / Q000737:chemistry; D014877:Water Pollution, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis*
chemical_list: D013729:Terpenes; D022882:Trihalomethanes