Control of lung epithelial growth by a nicotinic acetylcholine receptor: the other side of the coin.
This Commentary provides a perspective on an article in the current issue of the American Journal of Pathology by Maouche et al, which demonstrates that alpha7 nicotinic acetylcholine receptors play a key role in regulating airway regeneration by limiting basal epithelial cell proliferation.
Roman
Jesse
J
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Koval
Michael
M
D000818:Animals; D002038:Bungarotoxins / Q000378:metabolism; D004847:Epithelial Cells / Q000166:cytology / Q000502:physiology*; D006801:Humans; D009538:Nicotine / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000378:metabolism*; D020545:Respiratory Mucosa / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism
D002038:Bungarotoxins; D011978:Receptors, Nicotinic; D009538:Nicotine