Secoiridoid glucosides and unusual recyclized secoiridoid aglycones from Ligustrum vulgare.
Phytochemical investigation of the dried leaves and twigs of Ligustrum vulgare has led to the isolation of the secoiridoid glucosides, (2''R)- and (2''S)-10-hydroxy-2''-methoxyoleuropeins (1 and 2), and the secoiridoid aglycones, ligustrohemiacetals A (3) and B (4). Their structures were elucidated by spectroscopic and chemical means. Enzymatic hydrolysis of 10-hydroxyoleuropein to the analog of ligustrohemiacetals A and B led to the structural revision of jasmolactones.
Tanahashi
Takao
T
Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan. tanahash@kobepharma-u.ac.jp
Takenaka
Yukiko
Y
Okazaki
Naoaki
N
Koge
Megumi
M
Nagakura
Naotaka
N
Nishi
Toyoyuki
T
D006868:Hydrolysis; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification; D031659:Ligustrum / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves; D018547:Plant Stems
D039823:Iridoids; D010936:Plant Extracts