title: [Blood lipid spectrum in hypertensive patients and normotensive subjects living in the Khanty-Mansiysk region].
abstract: OBJECTIVE
  To evaluate basic parameters of lipid metabolism in patients with arterial hypertension (AH) stage I and II and normotensive subjects living in the far North of the Russian Federation (Khanty-Mansiysk Autonomic Region, Nyagan).
  
  
  METHODS
  Lipid spectrum was studied in 70 males and females with AH stage I and II, 280 normotensive males and females matched for sex, age, time of residence in the North.
  
  
  RESULTS
  Sex-related differences by concentrations of blood lipids become less pronounced with progression of AH while a concentration of atherogenic lipid fractions in AH patients rises. High prevalence of dyslipidemia, primarily hypercholesterolemia, in hypertensive and normotensive subjects is a prognostic factor of coronary atherosclerosis. Paired correlations indirectly confirm the effect of climatic factors on blood lipids.
  
  
  CONCLUSIONS
  It is necessary to correct lipid spectrum and risk factors in hypertensive and normotensive subjects as a prophylactic measure.
authors.forename: I M
authors.initials: IM
authors.lastname: Mikhaĭlova
authors.forename: L I
authors.initials: LI
authors.lastname: Gapon
authors.forename: V V
authors.initials: VV
authors.lastname: Belousov
authors.forename: O N
authors.initials: ON
authors.lastname: Startseva
authors.forename: S V
authors.initials: SV
authors.lastname: Alekseeva
mesh_terms: D000328:Adult; D001158:Arteries / Q000503:physiopathology; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000453:epidemiology*; D006973:Hypertension / Q000097:blood* / Q000453:epidemiology*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D012800:Siberia / Q000453:epidemiology
chemical_list: D008055:Lipids