title: Acid-mediated formation of trifluoromethyl sulfonates from sulfonic acids and a hypervalent iodine trifluoromethylating agent.
abstract: A variety of sulfonic acids have been trifluoromethylated using 1-trifluoromethyl-1,2-benziodoxol-3(1H)-one under mild conditions in good to excellent yields. Initial mechanistic investigations of this reaction show a clean second-order kinetics and only very weak substrate electronic effects.
authors.affiliation: Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zurich, 8093 Zurich, Switzerland.
authors.forename: Raffael
authors.initials: R
authors.lastname: Koller
authors.forename: Quentin
authors.initials: Q
authors.lastname: Huchet
authors.forename: Philip
authors.initials: P
authors.lastname: Battaglia
authors.forename: Jan M
authors.initials: JM
authors.lastname: Welch
authors.forename: Antonio
authors.initials: A
authors.lastname: Togni
mesh_terms: D000476:Alkanesulfonates / Q000737:chemistry*; D000498:Allyl Compounds; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D007455:Iodine; D008745:Methylation; D015394:Molecular Structure; D013451:Sulfonic Acids / Q000737:chemistry*
chemical_list: C546303:1-trifluoromethyl-1,2-benziodoxol-3(1H)-one; D000476:Alkanesulfonates; D000498:Allyl Compounds; D006846:Hydrocarbons, Halogenated; D013451:Sulfonic Acids; D007455:Iodine