title: Treating partial responders to antidepressant treatment.
abstract: Many patients with major depressive disorder only partially respond to initial antidepressant treatment. Residual depressive symptoms need to be addressed so that patients can achieve full remission and return to presymptomatic levels of functioning. This case vignette presents Ms M, a 26-year-old woman who continues to experience depression, fatigue, and sleepiness after adequate antidepressant therapy, and discusses pharmacologic strategies to relieve residual symptoms.
authors.affiliation: Mood Disorders Research Program and Clinic, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
authors.forename: Madhukar H
authors.initials: MH
authors.lastname: Trivedi
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D012074:Remission Induction; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents