A clinical survey of uveitis in HTLV-1 endemic region.
OBJECTIVE
To investigate a clinical survey of uveitis in southern Kyushu of Japan, where human T-lymphotropic virus type 1 (HTLV-1) and toxoplasmosis is highly endemic.


METHODS
The clinical records of patients with uveitis between 1975 and 2007 at Miyata Eye Hospital were reviewed.


RESULTS
A total number of 1338 patients (2012 eyes), consisting of 526 men and 812 women with mean age of 50.5 years old, were analyzed. The most common clinical entity was HTLV-1 uveitis (17.1%), followed by Vogt-Koyanagi-Harada disease (9.9%), sarcoidosis (7.2%), toxoplasmosis (7.1%), Behçet's disease (4.3%) and others. Unclassified uveitis comprised 41.1% in the series. Anterior uveitis was seen in 30.8%, intermediate uveitis in 17.3%, posterior uveitis in 9.3%, and pan-uveitis in 42.6%.


CONCLUSIONS
HTLV-1 uveitis and toxoplasmosis were the major clinical entities in southern Kyushu of Japan. This relates to the high seroprevalence of the infectious agents in this region of Japan.
Miyanaga
Masaru
M
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan.
Shimizu
Kentaro
K
Kawaguchi
Tatsushi
T
Miyata
Kazunori
K
Mochizuki
Manabu
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001528:Behcet Syndrome / Q000150:complications; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D015490:HTLV-I Infections / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications; D014123:Toxoplasmosis / Q000150:complications; D014605:Uveitis / Q000453:epidemiology* / Q000209:etiology* / Q000821:virology; D014606:Uveitis, Anterior / Q000453:epidemiology / Q000209:etiology; D015867:Uveitis, Intermediate / Q000453:epidemiology / Q000209:etiology; D015866:Uveitis, Posterior / Q000453:epidemiology / Q000209:etiology; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications; D055815:Young Adult