Development of a new disinfectant with very strong anti-influenza viral activity: a preliminary report.
OBJECTIVE
We evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses.


METHODS
The effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated.


RESULTS
This new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro.


CONCLUSIONS
This new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.
Takakuwa
Hiroki
H
Avian Influenza Research Centre, Kyoto Sangyo University, Motoyama Kamigamo, Kita-ku, Kyoto, 603-8555, Japan.
Maruoka
Toshiyuki
T
Hata
Tadayo
T
Miyazawa
Masaaki
M
Hata
Tomoyo
T
Toshimori
Hitoshi
H
Otsuki
Koichi
K