Clinical comparison of the plaque removal efficacy of a manual toothbrush with criss-cross bristle design.
OBJECTIVE
To compare the plaque removal efficacy of two manual toothbrushes: Oral-B Exceed and Asian Colgate 36 degrees manual toothbrush.


METHODS
The study used an examiner-blind, two-treatment, randomized, four-period (visits) crossover design. Subjects used each brush twice during the study. At the first visit, 41 subjects who met inclusion criteria and provided informed consent received a baseline plaque examination using the Turesky Modified Quigley-Hein Plaque Index. Subjects then used their assigned toothbrush for 1 minute with a marketed toothpaste without access to a mirror. Brushing was monitored. A post-brushing plaque exam was then performed. Subjects were rescheduled for their next visit in approximately 3 days. At visits 2, 3 and 4 the same disclosing, brushing and plaque grading procedures were followed. Subjects used their own products at home between visits.


RESULTS
39 subjects presented data for all four study periods; two subjects missed one period each. Baseline plaque scores were balanced between the two groups. Adjusted mean plaque removal (baseline minus post-brushing) scores were 0.479 for the Exceed toothbrush and 0.425 for the Asian Colgate 360 degrees toothbrush (P < 0.002). This translates to 12.7% greater plaque removal for the Exceed toothbrush versus the Asian Colgate 360 degrees toothbrush. No adverse events were reported during the study.
He
Tao
T
P&G Health Care Research Center, 8700 Mason-Montgomery Road, Mason, OH 45040, USA. he.t@pg.com
Li
Sarah
S
Sun
Lily
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D000328:Adult; D004396:Coloring Agents; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000473:pathology / Q000628:therapy*; D003774:Dental Plaque Index; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D013499:Surface Properties; D014099:Toothbrushing / Q000295:instrumentation*; D014100:Toothpastes / Q000627:therapeutic use; D055815:Young Adult
D004396:Coloring Agents; D014100:Toothpastes