Predictors of adherence to cognitive-behavioural therapy in first-episode psychosis.
OBJECTIVE
To investigate predictors of adherence with a cognitive-behavioural intervention in first-episode psychosis (FEP) patients.


METHODS
Predictors of adherence to cognitive-behavioural therapy (CBT) were longitudinally investigated in the experimental arm of a randomized controlled trial designed to evaluate the effectiveness of a CBT intervention for relapse prevention early in the course of psychosis when compared with treatment as usual within 2 high quality, youth oriented, specialist FEP programs (the EPISODE II trial).


RESULTS
Longer duration of untreated psychosis (DUP) and poorer level of insight predicted poor adherence to CBT. This association remained significant after controlling for potential confounders.


CONCLUSIONS
Treatment delay may decrease adherence with CBT in FEP patients. Reducing DUP and promoting insight early in the course of psychosis are likely to enhance adherence with CBT.
Alvarez-Jiménez
Mario
M
ORYGEN Youth Health Research Centre, Melbourne, Victoria, Australia. malvarez@unimelb.edu.au
Gleeson
John F
JF
Cotton
Sue
S
Wade
Darryl
D
Gee
Donna
D
Pearce
Tracey
T
Crisp
Kingsley
K
Spiliotacopoulos
Daniela
D
Newman
Belinda
B
McGorry
Patrick D
PD
D000293:Adolescent; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001364:Awareness; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D005196:Family Therapy; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010349:Patient Compliance / Q000523:psychology*; D011379:Prognosis; D011446:Prospective Studies; D011618:Psychotic Disorders / Q000523:psychology / Q000628:therapy*; D055502:Secondary Prevention; D016037:Single-Blind Method; D016896:Treatment Outcome; D055815:Young Adult
D014150:Antipsychotic Agents