title: Palladium-catalyzed annulation of 2-(1-alkynyl)biphenyls with aryl iodides to disubstituted methylidenefluorenes.
abstract: The palladium-catalyzed annulation reaction of 2-(1-alkynyl)biphenyls (1) with aryl iodides has been developed to prepare a variety of diarylmethylidenefluorenes (2). This method tolerates various functional groups in aryl iodide, such as OCH(3), CH(3), Cl, Br, Cf(3), and NO(2). All proceed in good yield with the exception of 4-iodonitrobenzene.
authors.affiliation: School of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
authors.forename: Chin-Chau
authors.initials: CC
authors.lastname: Chen
authors.forename: Shyh-Chyun
authors.initials: SC
authors.lastname: Yang
authors.forename: Ming-Jung
authors.initials: MJ
authors.lastname: Wu