title: [Apelin--a new protein-regulator in the cardiovascular system].
abstract: Apelin is an endogenic ligand of apelin (APJ) receptors widely expressed in human tissues. This protein is a peripheral vasodilator having a powerful positive inotropic action on myocardial contractility. This review describes mechanisms of interaction and apelin role in health and pathology.
authors.forename: S N
authors.initials: SN
authors.lastname: Tereshchenko
authors.forename: V P
authors.initials: VP
authors.lastname: Masenko
authors.forename: O V
authors.initials: OV
authors.lastname: Cherkavskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Shashkova
mesh_terms: D000804:Angiotensin II / Q000378:metabolism*; D000818:Animals; D000073861:Apelin; D000075244:Apelin Receptors; D002318:Cardiovascular Diseases / Q000378:metabolism*; D002319:Cardiovascular System / Q000378:metabolism*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics / Q000378:metabolism*
chemical_list: C115436:APLN protein, human; C104575:APLNR protein, human; D000073861:Apelin; D000075244:Apelin Receptors; D036341:Intercellular Signaling Peptides and Proteins; D043562:Receptors, G-Protein-Coupled; D000804:Angiotensin II