Spider bite (latrodectism) in Mashhad, Iran.
BACKGROUND
Spider (Latrodectus tredecimguttatus) bites are relatively common in North East Iran. They induce morbidity and rarely mortality. We aimed to investigate clinical, electrocardiographic and para-clinical changes in patients with this bite.


METHODS
All consecutive patients admitted with suspected spider bites between September 2005 and September 2006 were studied prospectively.


RESULTS
Spider bites accounted for 56 cases (0.5% of all poisoning, 21% of all admitted envenomated). The patients' mean (SD) age was 32 (16) years. The most common findings were pain (90%) mainly in their back (45%), stomach (35%), lower limbs (33%), upper limbs (19%) and chest (14%). Other clinical findings included were sweating (55%), chills (29%), dyspnea (25%), flushing (14%), spasm (12%), headache (12%), nausea (12%) and vertigo (12%). On electrocardiograph (ECG); ST segments were depressed in 25% of cases in at least two of the pre-cordial leads. Laboratory findings were in normal ranges. All the patients recovered following supportive and symptomatic treatment (no anti-toxin available in Iran), with a mean hospitalization period of 1.9 (1.3) days.


CONCLUSIONS
Spider (L. Tredecimguttatus) bite is relatively common in Mashhad, which induces latrodectism with relatively different findings and cardiac toxicity. ECG monitoring should be considered, particularly when specific anti-toxin is not available.
Afshari
R
R
Medical Toxicology Research Centre, Imam Reza (p) University Hospital, Mashhad University of Medical Sciences, Mashhad, I.R. Iran. AfshariR@mums.ac.ir
Khadem-Rezaiyan
M
M
Balali-Mood
M
M
D000293:Adolescent; D000328:Adult; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D001098:Spider Bites / Q000453:epidemiology* / Q000503:physiopathology