title: Efficient method for the synthesis of functionalized pyrazoles by catalyst-free one-pot tandem reaction of nitroalkenes with ethyl diazoacetate.
abstract: The one-pot synthesis of multisubstituted pyrazole derivatives was achieved via catalyst-free 1,3-dipolar cycloaddition of ethyl diazoacetate and nitroalkenes as the key step and elimination of the leaving group (NO(2) or Br) followed by intramolecular proton transfer with satisfactory yields.
authors.affiliation: Department of Chemistry and Life Science, Zhejiang Normal University, Jinhua, 321004, China. xiejw@zjnu.cn
authors.forename: Jian-Wu
authors.initials: JW
authors.lastname: Xie
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Yang
authors.forename: Li-Chun
authors.initials: LC
authors.lastname: Kong
authors.forename: Dong-Cheng
authors.initials: DC
authors.lastname: Xu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003979:Diazonium Compounds / Q000737:chemistry*; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D003979:Diazonium Compounds; D011720:Pyrazoles; C032111:diazoacetic ester