InBr3: a versatile catalyst for the different types of Friedel-Crafts reactions.
Mild and efficient InBr(3)-catalyzed Friedel-Crafts alkylation of heteroaromatic or electron-rich aromatic compounds with alpha-amido sulfones at room temperature in CH(2)Cl(2) has been developed. The products undergo further Friedel-Crafts alkylation with heteroaromatic or electron-rich aromatic compounds leading to unsymmetrical or bis-symmetrical triaryl methanes in good yield. Alpha-amido sulfones are employed for the synthesis of the unsymmetrical and bis-symmetrical triaryl methanes. The use of mild reaction condition, low catalytic loading, and high yield are the advantages of the present procedures.
Thirupathi
Ponnaboina
P
Department of Chemistry, Inha University, Incheon 402-751, South Korea.
Kim
Sung Soo
SS
D002384:Catalysis; D005025:Ethylene Dichlorides / Q000737:chemistry; D007204:Indium / Q000737:chemistry*; D015394:Molecular Structure
D005025:Ethylene Dichlorides; C530781:indium bromide; D007204:Indium; C024565:ethylene dichloride