title: Incidental extracolonic findings on bright lumen MR colonography in a population at increased risk for colorectal carcinoma.
abstract: OBJECTIVE
  Incidental extracolonic findings affect patient treatment and cost. Therefore, to consider magnetic resonance colonography (MRC) as a tool for colorectal cancer and polyps screening, more knowledge is needed on extracolonic findings. In this study, we sought to determine the prevalence and the spectrum of extracolonic findings in patients with an increased risk colorectal cancer that underwent bright lumen MRC.
  
  
  METHODS
  MRC examinations were performed in 210 patients. A gadolinium solution was administered rectally for distension of the colon. Extracolonic findings were scored by two radiologists and classified by using C-RADS Reporting System. All findings (with advice regarding work-up) were reported to the patient's physician and followed up for 4.5 years on average.
  
  
  RESULTS
  Extracolonic findings were found in 125 (59.5%) patients. Ten (4.8%) had "potentially important" findings (C-RADS category E4). Twenty-five patients (11.9%) had "likely unimportant" findings (E3), 90 (42.8%) had "clinically unimportant" findings (E2) and 85 (40.5%) had a normal exam (E1). In 14 (6.7%) patients additional work-up was performed for their incidentally discovered lesions. In three of them surgery was performed. After work-up, only in two (1.0%) patients a malignancy was found.
  
  
  CONCLUSIONS
  The number of new relevant extracolonic findings is small and the required additional work-up is limited. This should be considered for implementation of 'bright lumen' MRC as a screening tool.
authors.affiliation: Department of Radiology, Academic Medical Center, Amsterdam, Postbus 22660, 1100 DD Amsterdam, The Netherlands. angga.yusuf@gmail.com
authors.forename: Erlangga
authors.initials: E
authors.lastname: Yusuf
authors.forename: Jasper
authors.initials: J
authors.lastname: Florie
authors.forename: Chung Yung
authors.initials: CY
authors.lastname: Nio
authors.forename: Sebastian
authors.initials: S
authors.lastname: Jensch
authors.forename: Rutger A J
authors.initials: RA
authors.lastname: Nievelstein
authors.forename: Lubbertus
authors.initials: L
authors.lastname: Baak
authors.forename: Jaap
authors.initials: J
authors.lastname: Stoker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA