Bimanual motor coordination in agenesis of the corpus callosum.
The nature and extent of deficiencies in bimanual motor coordination in individuals with agenesis of the corpus callosum (ACC) was studied using the computerized Bimanual Coordination Test (cBCT). Compared with previous bimanual tasks, the cBCT is more specifically reliant on interhemispheric interactions of lateralized motor control, allows more precise measurement, and permits examination of performance over a wider range of bimanual challenges. The cBCT performance of 13 high-functioning individuals with complete ACC was compared to 21 age- and IQ-matched controls. The groups did not differ in unimanual response speed. On trials involving angled paths that require bimanual coordination, the ACC group performed significantly slower and less accurately across all angles. The largest group differences in speed occurred on trials where the hands must respond symmetrically, while mirror-image (vs. parallel) responding produced the greatest deficits in accuracy. These data confirm previous findings of deficits in bimanual coordination in callosal absence, but using significantly improved measurement technology. Deficits in bimanual coordination in ACC are present across different demands for interhand interactions in the speed and direction of movement.
Mueller
Kendra L Oakes
KL
Travis Research Institute, Fuller Graduate School of Psychology, Pasadena, California 91101, USA.
Marion
Sarah DeBoard
SD
Paul
Lynn K
LK
Brown
Warren S
WS
D055673:Acrocallosal Syndrome / Q000503:physiopathology*; D000293:Adolescent; D000328:Adult; D061085:Agenesis of Corpus Callosum; D000704:Analysis of Variance; D003337:Corpus Callosum / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000502:physiology*; D009483:Neuropsychological Tests; D009949:Orientation; D012042:Registries