title: Time domain algorithm for accelerated determination of the first  order moment of photo current fluctuations in high speed laser  Doppler perfusion imaging.
abstract: Advances in optical array sensor technology allow for the real time acquisition of dynamic laser speckle patterns generated by tissue perfusion, which, in principle,allows for real time laser Doppler perfusion imaging(LDPI). Exploitation of these developments is enhanced with the introduction of faster algorithms to transform photo currents into perfusion estimates using the first moment of the power spectrum. A time domain (TD)algorithm is presented for determining the first-order spectral moment. Experiments are performed to compare this algorithm with the widely used Fast Fourier Transform(FFT). This study shows that the TD-algorithm is twice as fast as the FFT-algorithm without loss of accuracy.Compared to FFT, the TD-algorithm is efficient in terms of processor time, memory usage and data transport.
authors.affiliation: MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands.
authors.forename: Matthijs
authors.initials: M
authors.lastname: Draijer
authors.forename: Erwin
authors.initials: E
authors.lastname: Hondebrink
authors.forename: Ton
authors.initials: T
authors.lastname: van Leeuwen
authors.forename: Wiendelt
authors.initials: W
authors.lastname: Steenbergen
mesh_terms: D000465:Algorithms; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D012039:Regional Blood Flow; D012815:Signal Processing, Computer-Assisted