title: Blood pressure and pulse wave velocity values in the institutionalized elderly aged 80 and over: baseline of the PARTAGE study.
abstract: OBJECTIVE
  The aim of the longitudinal study PARTAGE (predictive values of blood pressure and arterial stiffness in institutionalized very aged population) was to determine the predictive value of blood pressure (BP) and arterial stiffness for overall mortality, major cardiovascular events and cognitive decline in a large population of institutionalized patients aged 80 and over. In the study herein, we present the baseline data values of this study.
  
  
  METHODS
  A total of 1130 patients were recruited (878 women), living in French and Italian nursing homes. Clinical and 3-day self-measurements of BP were conducted. Aortic and upper limb pulse wave velocity were obtained using a PulsePen tonometer.
  
  
  RESULTS
  Of this population, 76% of women and 60% of men had a known hypertension and over 91% of the patients were under antihypertensive treatment; 51% of the treated hypertensive patients were well controlled (systolic BP <140 mmHg). No significant differences were found between clinical and self-measured BP. With age, there was an increase in pulse pressure (P < 0.001) due to a decrease in diastolic BP (P < 0.001), without any increase in systolic BP. Aortic but not peripheral pulse wave velocity significantly increased with age (P < 0.005).
  
  
  CONCLUSIONS
  Baseline values obtained herein demonstrate that elderly patients living in nursing homes present hemodynamic characteristics which are different to those described in community-living elderly populations, and indicate the interest of assessing, in longitudinal studies, the role of BP and arterial stiffness in morbidity and mortality in this population.
authors.affiliation: Department of Geriatrics, University Hospital of Nancy, Nancy, France. a.benetos@chu-nancy.fr
authors.forename: Athanase
authors.initials: A
authors.lastname: Benetos
authors.forename: Severine
authors.initials: S
authors.lastname: Buatois
authors.forename: Paolo
authors.initials: P
authors.lastname: Salvi
authors.forename: Francesca
authors.initials: F
authors.lastname: Marino
authors.forename: Olivier
authors.initials: O
authors.lastname: Toulza
authors.forename: Delphine
authors.initials: D
authors.lastname: Dubail
authors.forename: Patrick
authors.initials: P
authors.lastname: Manckoundia
authors.forename: Filippo
authors.initials: F
authors.lastname: Valbusa
authors.forename: Yves
authors.initials: Y
authors.lastname: Rolland
authors.forename: Olivier
authors.initials: O
authors.lastname: Hanon
authors.forename: Sylvie
authors.initials: S
authors.lastname: Gautier
authors.forename: Darko
authors.initials: D
authors.lastname: Miljkovic
authors.forename: Francis
authors.initials: F
authors.lastname: Guillemin
authors.forename: Mauro
authors.initials: M
authors.lastname: Zamboni
authors.forename: Carlos
authors.initials: C
authors.lastname: Labat
authors.forename: Christine
authors.initials: C
authors.lastname: Perret-Guillaume
mesh_terms: D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001011:Aorta / Q000502:physiology*; D001775:Blood Circulation / Q000502:physiology; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination; D005260:Female; D005602:France / Q000453:epidemiology; D006339:Heart Rate / Q000502:physiology; D006707:Homes for the Aged; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D007558:Italy / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D009735:Nursing Homes; D011237:Predictive Value of Tests; D011673:Pulsatile Flow / Q000502:physiology; D012648:Self Care
chemical_list: D000959:Antihypertensive Agents