title: A web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases (http://www.P450.kvl.dk).
abstract: Gene and genome duplication is a key driving force in evolution of plant diversity. This has resulted in a number of large multi-gene families. Two of the largest multi-gene families in plants are the cytochromes P450 (P450s) and family 1 glycosyltransferases (UGTs). These two families are key players in evolution, especially of plant secondary metabolism, and in adaption to abiotic and biotic stress. In the model plant Arabidopsis thaliana there are 246 and 112 cytochromes P450 and UGTs, respectively. The Arabidopsis P450, cytochromes b(5), NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases website (http://www.P450.kvl.dk) is a sequence repository of manually curated sequences, multiple sequence alignments, phylogenetic trees, sequence motif logos, 3D structures, intron-exon maps, and customized BLAST datasets.
authors.affiliation: Department of Biological Structure, University of Washington, HSB G-520/Box 357420, Seattle, WA 98195-7420, USA.
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Paquette
authors.forename: Kenneth
authors.initials: K
authors.lastname: Jensen
authors.forename: Søren
authors.initials: S
authors.lastname: Bak
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics*; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry / Q000235:genetics*; D042966:Cytochrome-B(5) Reductase / Q000235:genetics*; D015786:Cytochromes b5 / Q000235:genetics*; D018744:DNA, Plant; D019143:Evolution, Molecular; D017343:Genes, Plant; D018745:Genome, Plant; D016695:Glycosyltransferases / Q000235:genetics*; D020407:Internet; D008969:Molecular Sequence Data; D005810:Multigene Family; D010802:Phylogeny; D016415:Sequence Alignment
chemical_list: D018744:DNA, Plant; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; D042966:Cytochrome-B(5) Reductase; D016695:Glycosyltransferases