title: High prevalence of orthostatic hypotension in mild dementia.
abstract: OBJECTIVE
  Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia.
  
  
  METHODS
  Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria.
  
  
  RESULTS
  OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects.
  
  
  CONCLUSIONS
  OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls.
authors.affiliation: Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway. soho@sus.no
authors.forename: Hogne
authors.initials: H
authors.lastname: Sonnesyn
authors.forename: Dennis W
authors.initials: DW
authors.lastname: Nilsen
authors.forename: Arvid
authors.initials: A
authors.lastname: Rongve
authors.forename: Sabine
authors.initials: S
authors.lastname: Nore
authors.forename: Clive
authors.initials: C
authors.lastname: Ballard
authors.forename: Ole B
authors.initials: OB
authors.lastname: Tysnes
authors.forename: Dag
authors.initials: D
authors.lastname: Aarsland
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D015331:Cohort Studies; D003704:Dementia / Q000150:complications* / Q000453:epidemiology*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications* / Q000453:epidemiology*; D020961:Lewy Body Disease / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology; D008133:Long QT Syndrome / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D009483:Neuropsychological Tests; D011446:Prospective Studies