Intrinsic neutral and anionic structures of glutathione.
Gas-phase intrinsic structures of intact neutral and anionic glutathione (GSH) have been determined by means of a combination of negative ion photo-electron spectroscopy and quantum chemistry calculations. The inferred structures of the neutral parents of those peptide anions are canonical (non-zwitterionic). These intrinsic structures are compared to those already known in aqueous solution or determined by crystallography in binding sites of enzymes.
Ko
Yeon Jae
YJ
Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, USA.
Wang
Haopeng
H
Li
Xiang
X
Bowen
Kit H
KH
Lecomte
Frédéric
F
Desfrançois
Charles
C
Poully
Jean-Christophe
JC
Grégoire
Gilles
G
Schermann
Jean Pierre
JP
D000838:Anions / Q000737:chemistry; D005740:Gases; D005978:Glutathione / Q000737:chemistry*; D015394:Molecular Structure; D011789:Quantum Theory; D013057:Spectrum Analysis
D000838:Anions; D005740:Gases; D005978:Glutathione