title: [Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?].
abstract: The occurrence of metabolic syndrome (MS) and osteoporosis is essentials danger for public health. It seems that one of epidemiological factors of those diseases is age-depending adrenal androgens deficiency.
  
  
  OBJECTIVE
  was to evaluate relationships between DHEA/DHEAS serum levels and BMD along with frequency of MS in ageing Caucasian men.
  
  
  METHODS
  In 271 randomly chosen men aged 40 to 80 years living in Lubuskie district (Poland) adrenal androgens, anthropometrical indices in addition to densitometry were estimated.
  
  
  RESULTS
  DHEA/DHEAS serum levels showed positive correlation with BMD (r = 0.16 and r = 0.18, respectively, p < 0.001). Statistic essential dependencies between decreased adrenal androgens and coexistence of neoplastic diseases (p < 0.001), hypertension (p < 0.05), peripheral perfusion disturbances (p < 0.005) and dementia (p < 0.0001) were also observed.
  
  
  CONCLUSIONS
  The evaluation of DHEA/DHEAS serum level is useful in estimation of general health status of ageing men, but does not identify participants suffering from metabolic syndrome.
authors.affiliation: HERMED Out-Patient Clinic in Wschowa, Poland. wherman@wschowa.com.pl
authors.forename: Waldemar Adam
authors.initials: WA
authors.lastname: Herman
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Seńko
authors.forename: Izabela
authors.initials: I
authors.lastname: Korczowska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Łacka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D015897:Comorbidity; D003687:Dehydroepiandrosterone / Q000097:blood*; D003704:Dementia / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D054526:Men's Health; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology; D010024:Osteoporosis / Q000097:blood* / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D003687:Dehydroepiandrosterone