title: Research on focal nodular hyperplasia with MSCT and postprocessing.
abstract: OBJECTIVE
  To investigate and evaluate the pathological features and diagnostic value of focal nodular hyperplasia (FNH) with multi-section spiral computed tomography (MSCT) and postprocessing.
  
  
  METHODS
  A total of 25 patients with FNH who had undergone MSCT and postprocessing were included in the investigation. All patients had been pathologically or clinically confirmed with FNH. A number of 75 cases of hepatic carcinomas, hemangiomas and adenomas were randomly selected at a same period for a comparative study.
  
  
  RESULTS
  There was a single focus in 22 cases and multiple foci in 3 cases. On the plain scan, 17 lesions showed hypodensity, 7 isodensity and 4 hyperdensity (the case with fatty liver). With contrast, 28 lesions were enhanced evenly or in the nodules in the arterial phase; 13 lesions still showed hyperdensity, 11 lesions isodensity and 4 lesions hypodensity in the parenchymatous phase; in the delayed phase only 5 lesions showed hyperdensity but 9 lesions showed isodensity or slight hypodensity and 14 lesions showed hypodensity. Twelve lesions of 28 had central asteroid scars. Thickened feeding arteries in postprocessing were seen in 24 lesions, and were integrated into the parenchymatous lesions with a gradual and smooth course. On the contrary, there were no artery penetrated into the lesion found in any of comparative hepatic tumors.
  
  
  CONCLUSIONS
  Doctors could make a correct diagnosis and differentiation of FNH on evaluation of the characteristic appearance on MSCT with postprocessing.
authors.affiliation: Imaging and Interventional Center, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Yuan-Jian
authors.initials: YJ
authors.lastname: Liu
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Fan
authors.forename: Zhi-Dong
authors.initials: ZD
authors.lastname: Yuan
authors.forename: Peng-Cheng
authors.initials: PC
authors.lastname: Liu
authors.forename: Chun-Rong
authors.initials: CR
authors.lastname: Wang
authors.forename: Wei-Qiang
authors.initials: WQ
authors.lastname: Yan
authors.forename: Su-Mei
authors.initials: SM
authors.lastname: Wang
authors.forename: Jun-Hui
authors.initials: JH
authors.lastname: Chen
authors.forename: Zheng
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000236:Adenoma / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000792:Angiography / Q000379:methods*; D003936:Diagnosis, Computer-Assisted; D003937:Diagnosis, Differential; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000473:pathology*; D006391:Hemangioma / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008107:Liver Diseases / Q000175:diagnosis / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed / Q000379:methods*; D014057:Tomography, X-Ray Computed