title: Effect of biomedical organic compounds on the setting reaction of calcium phosphates.
abstract: In the present study, the effect of biomedical organic compounds (starch, sodium alginate, chitosan and gelatin) on the hydration of calcium phosphates was studied using X-ray diffraction, infrared spectroscopy, scanning electron microscopy and XPS analysis. Amorphous calcium phosphate (ACP) was prepared by a mechanochemical route and mixed with biomedical organic compounds. A solidification reaction occurred between ACP and dicalcium phosphate dihydrate (DCPD); the hydration product was poorly crystallized hydroxyapatite (HA). During the setting reaction of ACP and DCPD, the presence of biomedical organic compounds had an effect on the hydration product: the bonding energies of the primary elements (Ca, P) in the hydration product (HA) were changed; also different hydration morphologies, self-setting properties, rheological properties and mechanical strength of the cement were obtained. This work will allow advances in the synthesis of bionic composite calcium phosphate cement (CPC).
authors.affiliation: Key Laboratory of Specially Functional Materials of Ministry of Education and School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Yu
authors.forename: Jiandong
authors.initials: J
authors.lastname: Ye
authors.forename: Chengying
authors.initials: C
authors.lastname: Gao
authors.forename: Long
authors.initials: L
authors.lastname: Yu
authors.forename: Yingjun
authors.initials: Y
authors.lastname: Wang
mesh_terms: D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength / Q000187:drug effects; D003738:Dental Cements / Q000737:chemistry; D005780:Gelatin / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D009930:Organic Chemicals / Q000494:pharmacology*; D056951:Photoelectron Spectroscopy; D011134:Polysaccharides / Q000494:pharmacology*; D012212:Rheology / Q000187:drug effects; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; D003738:Dental Cements; D009930:Organic Chemicals; D011134:Polysaccharides; D005780:Gelatin