title: Consideration of endoscopic retrograde cholangiopancreatography in cases of acute biliary pancreatitis.
abstract: OBJECTIVE
  The important question to be answered in all cases of ABP is whether or not a calculous biliary obstruction is still present. Answering this question conditions subsequent management, including the need for endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study was to determine the relationship between persistent common bile duct stone (CBDS) and laboratory values, and dilation of bile duct in order to find possible significant associations in patients with acute biliary pancreatitis (ABP).
  
  
  METHODS
  Retrospectively, statistical evaluation of a group of 76 patients with ABP who had received early ERCP.
  
  
  RESULTS
  The prevalence of choledocholithiasis in patients > 70 years old was 54.2%, in patients < or = 70 years old it was 36.5%. Following cholecystectomy, CBDS was present in 81.8% of patients, p = 0.005. The probability of CBDS occurrence in patients > 70 years old with bile duct dilation was 81.3%; in the absence of bile duct dilation CBDS was not present, p < 0.001. The probability of CBDS occurrence in patients 70 years old with bile duct dilation was 57.7%, in the absence of bile duct dilation CBDS was present in 15.4%, p = 0.002. In patients with bile duct dilation predictive factors are as follows: bilirubin (Bi), after excluding patients with acute cholecystitis and cholangitis, p = 0.05; alanine aminotransferase (ALT) in patients 70 years old, p = 0.004; gamma-glutamyl transferase (GMT) in patients > 70 years old, p = 0.02.
  
  
  CONCLUSIONS
  ERCP is indicated in patients with ABP if biliary obstruction is present and the presence of a ductal stone is suspected. From our results it is clear that the predictive parameter for choledocholithiasis is the dilation of the bile duct and previous cholecystectomy. In patients with bile duct dilation possible predictive factors are Bi, ALT, and GMT (Tab. 1, Fig. 8, Ref. 20).
authors.affiliation: Internal Gastroenterology Clinic, University Hospital, Martin, Slovakia. martahorakova@zoznam.sk
authors.forename: M
authors.initials: M
authors.lastname: Horakova
authors.forename: I
authors.initials: I
authors.lastname: Vadovicova
authors.forename: I
authors.initials: I
authors.lastname: Katuscak
authors.forename: J
authors.initials: J
authors.lastname: Janik
authors.forename: P
authors.initials: P
authors.lastname: Makovnik
authors.forename: J
authors.initials: J
authors.lastname: Sadlonova
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde; D042883:Choledocholithiasis / Q000150:complications* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000000981:diagnostic imaging* / Q000209:etiology; D055815:Young Adult