title: [First episode of psychosis intensive early intervention programme versus standard treatment--secondary publication].
abstract: A total of 547 patients with a first episode of psychosis were randomised to two years of intensive early intervention programme (OPUS) versus standard treatment. OPUS treatment consisted of Assertive Community Treatment (ACT) with manuals for family involvement and social skills training. Standard treatment comprised contact with a community mental health centre. OPUS treatment improved the clinical outcome after two years of treatment, but the effects were not sustainable up to five years after. The secondary outcome measures showed a difference on supported housing and use of bed-days at the five-year follow-up in favour of OPUS treatment.
authors.affiliation: Bispebjerg, Psykiatrisk Center Sct Hans, og Arhus Universitetshospital, Risskov.
authors.forename: Mette
authors.initials: M
authors.lastname: Bertelsen
authors.forename: Pia
authors.initials: P
authors.lastname: Jeppesen
authors.forename: Lone
authors.initials: L
authors.lastname: Petersen
authors.forename: Anne
authors.initials: A
authors.lastname: Thorup
authors.forename: Johan
authors.initials: J
authors.lastname: Øhlenschlaeger
authors.forename: Phuong
authors.initials: P
authors.lastname: le Quach
authors.forename: Torben Østergaard
authors.initials: TØ
authors.lastname: Christensen
authors.forename: Gertrud
authors.initials: G
authors.lastname: Krarup
authors.forename: Per
authors.initials: P
authors.lastname: Jørgensen
authors.forename: Merete
authors.initials: M
authors.lastname: Nordentoft
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001242:Assertiveness; D003155:Community Mental Health Centers; D003156:Community Mental Health Services; D005196:Family Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D012008:Recurrence; D012951:Socialization; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents