Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans.
Candida albicans Hwp1, Hwp2, and Rbt1 are related cell wall proteins expressed during the programs of sexual differentiation and filamentous growth. In this study, we compare strains lacking either single factors or a combination of these genes, and we demonstrate distinct but overlapping roles in mating and biofilm formation.
Ene
Iuliana V
IV
Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
Bennett
Richard J
RJ
D018441:Biofilms / Q000254:growth & development*; D002176:Candida albicans / Q000166:cytology / Q000235:genetics* / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism; D005656:Fungal Proteins / Q000378:metabolism*; D049770:Genes, Mating Type, Fungal; D008562:Membrane Glycoproteins / Q000378:metabolism*
D005656:Fungal Proteins; C118102:HWP1 protein, Candida albicans; D008562:Membrane Glycoproteins