title: Acute tubular necrosis associated with non-hemorrhagic Dengue fever: a case report.
abstract: Dengue fever (DF) is an arthropod-born viral infection affecting humans. Dengue viruses are transmitted through the bites of the mosquito Aedes aegypti. Acute renal failure (ARF) is reported in patients who are affected mainly with Dengue hemorrhagic fever (DHF), which is a severe presentation of the disease. We report the case of a 24-year-old Omani female with no past history of particular medical problems. She was referred to our hospital for the further management of acute renal failure. She had clinical features of DF without DHF. The kidney biopsy showed features of acute tubular necrosis (ATN). She had a complete recovery after 25 days and required three sessions of hemodialysis. We conclude that DF even without DHF may lead to ATN and ARF. Clinicians should be aware of this etiology. Treatment is supportive and may require dialysis. The prognosis could be favorable.
authors.affiliation: Department of Nephrology, Royal Hospital, P.O. Box 1331, PC 111, Muscat, Oman. nabmoh@omantel.net
authors.forename: N
authors.initials: N
authors.lastname: Mohsin
authors.forename: E
authors.initials: E
authors.lastname: Mohamed
authors.forename: M
authors.initials: M
authors.lastname: Gaber
authors.forename: I
authors.initials: I
authors.lastname: Obaidani
authors.forename: M
authors.initials: M
authors.lastname: Budruddin
authors.forename: S
authors.initials: S
authors.lastname: Al Busaidy
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D003715:Dengue / Q000150:complications*; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000473:pathology*; D009336:Necrosis; D006435:Renal Dialysis; D055815:Young Adult