Topiramate induced acute transient myopia: a case report.
BACKGROUND
Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and for prophylaxis of migraine. This article describes a case of topiramate induced acute transient myopia. The underlying mechanism and management is discussed.


METHODS
A 34-year-old female complained of sudden onset of blurred vision, 9 days prior to this she had commenced topiramate therapy for migraine prophylaxis. Visual acuity was reduced to 6/36 right eye and 2/60 left eye. Examination revealed ocular anatomical and myopic refractive changes which resolved quickly following discontinuation of the drug.


CONCLUSIONS
Ophthalmologists need to be aware of the potential ocular side effects of topiramate. Although relatively rare prompt recognition is key so appropriate management can be instituted.
Gawley
Sandra D
SD
St Paul's Eye Unit, The Royal Liverpool University Hospital Prescot Street, Liverpool, Merseyside UK. sandragawley@hotmail.com