title: Hospital-based surveillance of rotavirus and other viral agents of diarrhea in children and adults in Russia, 2005-2007.
abstract: During a 2-year period in 2005-2007, we conducted surveillance of group A rotaviruses and other enteric agents among patients hospitalized with acute gastroenteritis in 8 different cities of the Russian Federation. Fecal specimens were gathered from 3208 children (including 2848 children aged <5 years) and 1354 adults who were admitted to hospitals in Moscow, St. Petersburg, Chelyabinsk, Nizhnii Novgorod, Tyumen, Khabarovsk, Makhachkala, and Yakutsk. Polymerase chain reaction was performed to detect rotaviruses of groups A and C, noroviruses of genogroups I and II, astrovirus, sapovirus, and enteric adenoviruses (group F). Group A rotavirus was the most common viral pathogen detected among children aged <5 years (43.6%), followed by norovirus (12.5%), whereas norovirus was the pathogen most commonly detected in adults (11.9%). P and G genotypes were determined for 515 rotavirus specimens, and the most prevalent genotypes were G1P[8] (44.9%), G4P[8] (40.0%), G2P[4] (8.5%), and G3P[8] (6.6%). This study is the first multicenter study of rotaviruses in the Russian Federation and documents the important burden of disease caused by this pathogen, which soon may be preventable by vaccination.
authors.affiliation: Central Research Institute of Epidemiology, Moscow, Russia. apodkolzin@pcr.ru
authors.forename: A T
authors.initials: AT
authors.lastname: Podkolzin
authors.forename: E B
authors.initials: EB
authors.lastname: Fenske
authors.forename: N Yu
authors.initials: NY
authors.lastname: Abramycheva
authors.forename: G A
authors.initials: GA
authors.lastname: Shipulin
authors.forename: O I
authors.initials: OI
authors.lastname: Sagalova
authors.forename: V N
authors.initials: VN
authors.lastname: Mazepa
authors.forename: G N
authors.initials: GN
authors.lastname: Ivanova
authors.forename: A V
authors.initials: AV
authors.lastname: Semena
authors.forename: Z G
authors.initials: ZG
authors.lastname: Tagirova
authors.forename: M N
authors.initials: MN
authors.lastname: Alekseeva
authors.forename: V P
authors.initials: VP
authors.lastname: Molochny
authors.forename: U D
authors.initials: UD
authors.lastname: Parashar
authors.forename: J
authors.initials: J
authors.lastname: Vinjé
authors.forename: V V
authors.initials: VV
authors.lastname: Maleev
authors.forename: R I
authors.initials: RI
authors.lastname: Glass
authors.forename: V I
authors.initials: VI
authors.lastname: Pokrovsky
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology*; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D012401:Rotavirus / Q000145:classification / Q000235:genetics; D012400:Rotavirus Infections / Q000453:epidemiology*; D012426:Russia / Q000453:epidemiology; D012621:Seasons; D013997:Time Factors