title: Synthesis and biological activity of novel oxazolidinones.
abstract: A number of 5-substituted derivatives of Ranbezolid, a novel oxazolidinone were synthesized. Antibacterial activity of the compounds against a number of sensitive and resistant bacteria showed promising results.
authors.affiliation: Department of Medicinal Chemistry, New Drug Discovery Research, Ranbaxy Research Laboratories, Plot-20, Sector-18, Udyog Vihar, Gurgaon 122001, India. biswajit.das@ranbaxy.com
authors.forename: Biswajit
authors.initials: B
authors.lastname: Das
authors.forename: A V S
authors.initials: AV
authors.lastname: Rajarao
authors.forename: Sonali
authors.initials: S
authors.lastname: Rudra
authors.forename: Ajay
authors.initials: A
authors.lastname: Yadav
authors.forename: Abhijit
authors.initials: A
authors.lastname: Ray
authors.forename: Manisha
authors.initials: M
authors.lastname: Pandya
authors.forename: Ashok
authors.initials: A
authors.lastname: Rattan
authors.forename: Anita
authors.initials: A
authors.lastname: Mehta
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D001419:Bacteria; D015195:Drug Design; D005663:Furans; D008826:Microbial Sensitivity Tests; D010080:Oxazoles; D023303:Oxazolidinones / Q000138:chemical synthesis / Q000494:pharmacology*; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D005663:Furans; D010080:Oxazoles; D023303:Oxazolidinones; C476340:ranbezolid