Surgical techniques for multimodality treatment of malignant pleural mesothelioma: extrapleural pneumonectomy and pleurectomy/decortication.
Trimodality treatment of malignant pleural mesothelioma with cytoreductive surgery followed by radiation and chemotherapy has resulted in long-term survival for a select group of patients. Knowledge of the similarities and differences between the two operations that have evolved-extrapleural pneumonectomy and pleurectomy/decortication-is prerequisite to understanding the complex issues associated with patient selection, diagnosis, pathologic staging, preoperative assessment, perioperative management, and adjuvant treatment. Both operations are technically complex and should only be performed at experienced high-volume centers.
Wolf
Andrea S
AS
Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusettes 02115, USA.
Daniel
Jonathan
J
Sugarbaker
David J
DJ
D000758:Anesthesia; D017024:Chemotherapy, Adjuvant; D002983:Clinical Competence; D006801:Humans; D008654:Mesothelioma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D018579:Patient Selection; D010997:Pleural Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011013:Pneumonectomy / Q000009:adverse effects; D018714:Radiotherapy, Adjuvant; D019616:Thoracic Surgical Procedures / Q000009:adverse effects; D016896:Treatment Outcome