title: Detection of atherosclerotic progression with rupture of degenerated in-stent intima five years after bare-metal stent implantation using optical coherence tomography.
abstract: In-stent intimal hyperplasia peaks in the early phase (6-12 months) after bare-metal stent (BMS) implantation. However, late luminal re-narrowing due to atherosclerotic progression of in-stent intima is reported beyond 4 years. We report the optical coherence tomographic findings of a case of late restenosis of BMS 5 years after implantation. Remarkable in-stent intimal growth was observed, demonstrating a heterogeneous appearance including low-intensity areas and accompanied by intimal rupture. These findings were similar to the morphology of ruptured fibroatheroma in the native coronary artery, and suggested that atherosclerotic change in the in-stent intima occurred over the 5 years following BMS implantation.
authors.affiliation: Division of Cardiovascular Medicine, Toyohashi Heart Center, 21-1 Gobudori, Oyama-cho, Toyohashi, 441-8530, Japan.
authors.forename: Maoto
authors.initials: M
authors.lastname: Habara
authors.forename: Mitsuyasu
authors.initials: M
authors.lastname: Terashima
authors.forename: Takahiko
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000473:pathology*; D054059:Coronary Occlusion / Q000628:therapy; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012421:Rupture / Q000175:diagnosis / Q000473:pathology; D015607:Stents / Q000009:adverse effects*; D041623:Tomography, Optical Coherence; D017539:Tunica Intima / Q000293:injuries*