Subcutaneous metastasis of prostate cancer.
OBJECTIVE
Prostate cancer tends to spread to regional lymph nodes and bone, and, to a lesser degree, to lung, liver, and brain. Metastases in other locations are exceptional. To review the frequency and clinical characteristics of metastasis to subcutaneous cellular tissue in adenocarcinoma of the prostate.


METHODS
The case of a 71-year-old man diagnosed of adenocarcinoma of the prostate is reported. The patient underwent radical prostatectomy and artificial sphincter for stress urinary incontinence.


RESULTS
During follow-up the patient showed biochemical progression, local recurrence, and bone metastasis. The disease metastasized in the subcutaneous tissue around the reservoir of the artificial sphincter.


CONCLUSIONS
Prostate cancer is highly prevalent in our part of the world. The clinical finding of metastasis in organs other than bone or regional lymph nodes is accompanied by a short survival. Metastases in subcutaneous tissue may be underdiagnosed due to its indolent clinical course and possible absence of PSA elevation. In any case, subcutaneous metastases have an unfavorable prognosis.
Aranzubía
Oscar Miranda
OM
Urology Department I, Central University Hospital of Asturias, Oviedo, Spain. mirandaaranzubia@gmail.com
Rodríguez
Jorge García
JG
Allende
Blanca Vivanco
BV
Gómez
Jesús María Fernández
JM
González
Raquel Sacristán
RS
Múgica
Miguel Alvarez
MA
Sejas
Francisco Javier Regadera
FJ
D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D040521:Subcutaneous Tissue