title: Disseminated Trichosporon spp infection in preterm newborns: a case report.
abstract: OBJECTIVE
  To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients.
  
  
  METHODS
  A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.
  
  
  CONCLUSIONS
  The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.
authors.affiliation: Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. dnp@via-rs.net
authors.forename: Denise N
authors.initials: DN
authors.lastname: Pereira
authors.forename: Silvana S
authors.initials: SS
authors.lastname: Nader
authors.forename: Paulo
authors.initials: P
authors.lastname: Nader
authors.forename: Patrícia G
authors.initials: PG
authors.lastname: Martins
authors.forename: Silvana P
authors.initials: SP
authors.lastname: Furlan
authors.forename: Cláudia R
authors.initials: CR
authors.lastname: Hentges
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood; D008297:Male; D009181:Mycoses / Q000382:microbiology*; D014250:Trichosporon / Q000302:isolation & purification*