title: Adrenocortical cancer.
abstract: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy causing up to 0.2% of all cancer deaths This article reviews the incidence, presentation, and pathology of ACC. Particular attention is paid to the molecular oncogenesis of this disease, and the surgical and therapeutic options available for its cure.
authors.affiliation: Translational Genomics Research Institute, Clinical Translational Research Division, Phoenix, AZ 85004, USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Wandoloski
authors.forename: Kimberly J
authors.initials: KJ
authors.lastname: Bussey
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Demeure
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D020022:Genetic Predisposition to Disease; D006801:Humans; D008939:Mitotane / Q000627:therapeutic use
chemical_list: D018931:Antineoplastic Agents, Hormonal; D008939:Mitotane