Enuresis in hyperthyroidism: a temporary lack of central control mechanism leads to nocturnal enuresis.
We report on a 9-year-old boy who suffered from hyperthyroidism and a new appearance of enuresis. Bedwetting ceased and prepulse inhibition (PPI) - measured as a parameter of central control - increased during the course of therapy.


CONCLUSIONS
The increase in PPI is an indication that enuresis in hyperthyroidism could be as a result of a temporary loss of central control on brainstem reflexes. The case conveys new insights into the correlation between thyroid hormones and micturition patterns and the aetiology of enuresis.
Meir
J
J
Hospital for Children and Adolescents, University Leipzig, Leipzig, Germany.
Roessner
D
D
Eggert
P
P
D013956:Antithyroid Agents / Q000627:therapeutic use; D001933:Brain Stem / Q000503:physiopathology*; D002648:Child; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008713:Methimazole / Q000627:therapeutic use; D009433:Neural Inhibition; D053206:Nocturnal Enuresis / Q000209:etiology*; D013216:Reflex, Startle
D013956:Antithyroid Agents; D008713:Methimazole