[Isolation and identification of chemical constituents from peels of Citrus changshan-huyou Y.B. Chang].
OBJECTIVE
To study the chemical constituents of the peels collected from Citrus changshan-huyou Y. B. Chang, and further screen the bioactive components as the lead structures.


METHODS
These compounds were isolated by repeated flash column chromatography on silica gel and Sephadex LH-20. The structures of isolated compounds were elucidated by using IR, EIMS, and NMR analyses.


RESULTS
One novel compound along with nine known compounds were obtained and identified as huyoujiasu(I), 3-hydroxy-4-methoxybenzoic acid(II), 3, 4-dihydroxybenzoic acid(III), fatty acid(IV), glyceride(V), 6, 7-dimethoxycoumarin(VI), 6', 7'-dihydroxybergamottin(VII), daucossterol A(VIII), daucossterol B(IX) and huyou-triterpenoid(X).


CONCLUSIONS
One new compound, Huyoujiasu, was obtained from these peels by repeated column chromatography, and the other known compounds were isolated from this fruit for the first time as well.
Zhao
Xue Mei
XM
Pharmacy College, Taishan Medical University, Taian 271016, China. zhaoxuem@eyou.com
Ye
Xing Qian
XQ
Zhu
Da Yuan
DY
D002845:Chromatography / Q000379:methods; D002957:Citrus / Q000737:chemistry* / Q000145:classification; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry*; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification
D003374:Coumarins; D062385:Hydroxybenzoates; D010636:Phenols; D012855:Sitosterols; C546741:huyouyisu; C009091:protocatechuic acid; C018145:scoparone; C011015:lyoniside