Gamma oscillations in the primary motor cortex studied with MEG.
In recent years, there has been a growing interest on the role of gamma band (>30 Hz) neural oscillations in motor control, although the function of this activity in motor control is unknown clearly. With the goal of discussing the high frequency sources non-invasively and precisely during unilateral index finger movement, we investigated gamma band oscillations in 20 right-handed normal adults with magnetoencephalography (MEG). The results showed that gamma band activity appeared only during finger movement. Nineteen subjects displayed consistently contralateral event-related synchronization (C-ERS) within high gamma band (70-150 Hz) in primary motor cortex (M1) of both hemispheres. Interestingly, 15 subjects displayed ipsilateral event-related desynchronization (I-ERD) and C-ERS within broad gamma band (30-150 Hz). The locations of the broad gamma band I-ERD and C-ERS revealed hemispherical symmetry in M1. These findings demonstrate that there are consistent high gamma C-ERS and inconsistent low gamma I-ERD during a simple finger movement in the motor cortex. This study provides new evidence for the use of high gamma frequency oscillations as biomarkers in the analyses of functional brain activity and the localization of the motor cortex.
Huo
Xiaolin
X
Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. huoxl@mail.iee.ac.cn
Xiang
Jing
J
Wang
Yingying
Y
Kirtman
Elijah G
EG
Kotecha
Rupesh
R
Fujiwara
Hisako
H
Hemasilpin
Nat
N
Rose
Douglas F
DF
Degrauw
Ton
T
D000328:Adult; D015415:Biomarkers; D001931:Brain Mapping; D003344:Cortical Synchronization; D004569:Electroencephalography; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D005385:Fingers / Q000294:innervation; D007839:Functional Laterality; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology*; D010507:Periodicity; D055815:Young Adult
D015415:Biomarkers