title: Axillary silicone lymphadenopathy presenting with a lump and altered sensation in the breast: a case report.
abstract: BACKGROUND
  Silicone lymphadenopathy is a rare but recognised complication of procedures involving the use of silicone. It has a poorly understood mechanism but is thought to occur following the transportation of silicone particles from silicone-containing prostheses to lymph nodes by macrophages.
  
  
  METHODS
  We report of a case involving a 35-year-old woman who presented to the breast clinic with a breast lump and altered sensation below her left nipple 5 years after bilateral cosmetic breast augmentations. A small lump was detected inferior to the nipple but clinical examination and initial ultrasound investigation showed both implants to be intact. However, mammography and magnetic resonance imaging of both breasts revealed both intracapsular and extracapsular rupture of the left breast prosthesis. The patient went on to develop a flu-like illness and tender lumps in the left axilla and right mastoid regions. An excision biopsy of the left axillary lesion and replacement of the ruptured implant was performed. Subsequent histological analysis showed that the axillary lump was a lymph node containing large amounts of silicone.
  
  
  CONCLUSIONS
  The exclusion of malignancy remains the priority when dealing with lumps in the breast or axilla. Silicone lymphadenopathy should however be considered as a differential diagnosis in patients in whom silicone prostheses are present.
authors.affiliation: University Hospital of North Durham North Road, Durham, County Durham DH1 5TW UK.
authors.forename: Simon T
authors.initials: ST
authors.lastname: Adams
authors.forename: Julie
authors.initials: J
authors.lastname: Cox
authors.forename: G Sam
authors.initials: GS
authors.lastname: Rao