title: Aging: fruit flies break the chain to a longer life.
abstract: Mitochondria have long had an enigmatic role in the biology of aging. New research in Drosophila reveals an evolutionarily conserved function for the mitochondrial electron transport chain in the modulation of animal lifespan.
authors.affiliation: University of Michigan Geriatrics Center, Department of Molecular and Integrative Physiology, Basic Sciences and Research Building, Ann Arbor, MI 49108, USA.
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Linford
authors.forename: Scott D
authors.initials: SD
authors.lastname: Pletcher
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D004330:Drosophila / Q000502:physiology*; D045222:Electron Transport Chain Complex Proteins / Q000235:genetics / Q000502:physiology*; D008136:Longevity / Q000235:genetics / Q000502:physiology*; D010641:Phenotype; D034622:RNA Interference
chemical_list: D045222:Electron Transport Chain Complex Proteins