New genotype of dengue type 3 virus circulating in Brazil and Colombia showed a close relationship to old Asian viruses.
Dengue type 3 genotype V viruses have been recently detected in Brazil and Colombia. In this study, we described another Brazilian isolate belonging to this genotype. Phylogenetic analysis including dengue type 3 viruses isolated worldwide showed that Brazilian and Colombian viruses were closely related to viruses isolated in Asia more than two decades ago. The characteristic evolutionary pattern of dengue type 3 virus cannot explain the close similarity of new circulating viruses with old viruses. Further studies are needed to confirm the origin of the new dengue type III genotype circulating in Brazil and Colombia.
Aquino
Victor Hugo
VH
Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brasil. vhugo@fcfrp.usp.br
Amarilla
Alberto Anastacio
AA
Alfonso
Helda Liz
HL
Batista
Weber Cheli
WC
Figueiredo
Luiz Tadeu Moraes
LT
D020413:3' Untranslated Regions; D001938:Brazil; D003105:Colombia; D003715:Dengue / Q000097:blood / Q000821:virology*; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics*; D019143:Evolution, Molecular; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D014759:Viral Envelope Proteins / Q000235:genetics; D017361:Viral Nonstructural Proteins / Q000235:genetics; D014780:Viruses / Q000235:genetics*
D020413:3' Untranslated Regions; C084188:E protein, Dengue virus type 3; C546113:NS1 protein, Dengue virus type 3; D012367:RNA, Viral; D014759:Viral Envelope Proteins; D017361:Viral Nonstructural Proteins