Treatment of subcutaneous phaeohyphomycosis and prospective follow-up of 17 kidney transplant recipients.
BACKGROUND
Subcutaneous phaeohyphomycosis in solid organ recipients may have an adverse outcome.


OBJECTIVE
We sought to describe the disease course, treatment, and outcome of allograft function in kidney transplant recipients with phaeohyphomycosis.


METHODS
Seventeen patients were followed for a mean period of 25.4 months to analyze the clinical response to treatment.


RESULTS
There was no treatment failure or relapsing disease among 12 patients who completed treatment. Two patients were still in treatment with disease remission. One patient discontinued the study during treatment with partial remission, one died after finishing treatment with disease remission, and one was dropped from the study because contact was lost. Immunosuppressive regimens were not changed. Two of 17 patients had a significant reduction in allograft function.


CONCLUSIONS
The follow-up time was short and the number of patients was small.


CONCLUSIONS
The outcome of phaeohyphomycosis in kidney transplant recipients was favorable with minimal impact on renal allograft function.
Ogawa
Marília Marufuji
MM
Department of Dermatology, Federal University of São Paulo, São Paulo, Brazil.
Galante
Nelson Zocoler
NZ
Godoy
Patrício
P
Fischman-Gompertz
Olga
O
Martelli
Flavia
F
Colombo
Arnaldo Lopes
AL
Tomimori
Jane
J
Medina-Pestana
José Osmar
JO
D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003404:Creatinine / Q000097:blood; D003881:Dermatomycoses / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000503:physiopathology; D016030:Kidney Transplantation / Q000276:immunology* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000175:diagnosis / Q000628:therapy
D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D003404:Creatinine