Practical disk diffusion test for detecting group B streptococcus with reduced penicillin susceptibility.
Although group B streptococcus (GBS) has been considered to be uniformly susceptible to beta-lactams, the presence of GBS with reduced penicillin susceptibility (PRGBS) was recently confirmed genetically. We developed a feasible and reliable method for screening PRGBS in clinical microbiology laboratories using a combination of ceftibuten, oxacillin, and ceftizoxime disks.
Kimura
Kouji
K
Department of Bacteriology II, National Institute of Infectious Disease, Tokyo 208-0011, Japan.
Wachino
Jun-Ichi
J
Kurokawa
Hiroshi
H
Suzuki
Satowa
S
Yamane
Kunikazu
K
Shibata
Naohiro
N
Arakawa
Yoshichika
Y
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000077722:Ceftibuten; D015296:Ceftizoxime / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests / Q000379:methods*; D006801:Humans; D010068:Oxacillin / Q000494:pharmacology; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins; D015296:Ceftizoxime; D000077722:Ceftibuten; D010068:Oxacillin