title: Ultrasound promoted efficient method for the cleavage of 3-aryl-2,3-epoxyl-1-phenyl-1-propanone with indole.
abstract: An efficient synthesis of 3-aryl-3-hydroxy-2-(1H-indol-3-yl)-1-phenyl-1-propanone via the cleavage of epoxides with indole promoted by ultrasound irradiation was carried out in good yields by using montmorillonite K10-ZnCl(2) within 2-5h at room temperature. This method provides several advantages such as operational simplicity, high yield and mild conditions.
authors.affiliation: College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Key Laboratory of Medical Chemistry and Molecular Diagnosis, Ministry of Education, Baoding, PR China. lijitai@hbu.cn
authors.forename: Ji-Tai
authors.initials: JT
authors.lastname: Li
authors.forename: Ming-Xuan
authors.initials: MX
authors.lastname: Sun
authors.forename: Ying
authors.initials: Y
authors.lastname: Yin
mesh_terms: D001546:Bentonite / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D002712:Chlorides / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D013696:Temperature; D013997:Time Factors; D014465:Ultrasonics; D017967:Zinc Compounds / Q000737:chemistry
chemical_list: D002712:Chlorides; D004852:Epoxy Compounds; D007211:Indoles; D017967:Zinc Compounds; D001546:Bentonite; C016837:zinc chloride