title: Structural studies of an immunoenhancing water-soluble glucan isolated from hot water extract of an edible mushroom, Pleurotus florida, cultivar Assam Florida.
abstract: An immunoenhancing polysaccharide isolated from the hot water extract of the fruiting bodies of an edible mushroom Pleurotus florida, cultivar Assam Florida, was found to consist of only d-glucose as a monosaccharide constituent. On the basis of total acid hydrolysis, methylation analysis, periodate oxidation, Smith degradation, and NMR experiments ((1)H, (13)C, DEPT-135, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC), the structure of the repeating unit of the polysaccharide was established as This glucan stimulates macrophages, splenocytes, and thymocytes.
authors.affiliation: Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721 102, West Bengal, India.
authors.forename: Sadhan K
authors.initials: SK
authors.lastname: Roy
authors.forename: Debsankar
authors.initials: D
authors.lastname: Das
authors.forename: Subhas
authors.initials: S
authors.lastname: Mondal
authors.forename: Debabrata
authors.initials: D
authors.lastname: Maiti
authors.forename: Bibhas
authors.initials: B
authors.lastname: Bhunia
authors.forename: Tapas K
authors.initials: TK
authors.lastname: Maiti
authors.forename: Syed S
authors.initials: SS
authors.lastname: Islam
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000818:Animals; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D005936:Glucans / Q000737:chemistry* / Q000276:immunology*; D005947:Glucose / Q000032:analysis; D008262:Macrophage Activation / Q000187:drug effects; D008264:Macrophages / Q000166:cytology / Q000276:immunology; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D012995:Solubility; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology; D014867:Water
chemical_list: D005936:Glucans; D014867:Water; D005947:Glucose