title: [Hypokalemic paralysis revealing Sjögren's syndrome associated with auto-immune thyroiditis].
abstract: We report a case of 36-year-old woman, admitted for hypotonic tetraparesis. Laboratory tests revealed severe hypokalaemia, acidosis, hyperchloremia and alkaline urinary pH allowing the diagnosis of distal tubular acidosis. Additional investigations led to the diagnosis of primary Sjögren's syndrome associated with Hashimoto's thyroïditis. The evolution was favorable under potassium citrate alkalinisation, the corticosteroid therapy and hormonal substitution. Based on this observation, the pathogenesis of distal tubular acidosis during auto-immune diseases (Sjögren's syndrome, monoclonal hypergammaglobulinemia, hypothyroidism) was discussed as well as its consequences and management.
authors.affiliation: Service de médecine interne, hôpital militaire Moulay Ismaïl, Meknès, Maroc.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Baaj
authors.forename: Somaya
authors.initials: S
authors.lastname: Safi
authors.forename: Hassna
authors.initials: H
authors.lastname: Hassikou
authors.forename: Fatima
authors.initials: F
authors.lastname: Tabache
authors.forename: Karim
authors.initials: K
authors.lastname: Mouden
authors.forename: Larbi
authors.initials: L
authors.lastname: Hadri
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013967:Thyroiditis, Autoimmune / Q000150:complications*