Synchronous myeloproliferative and inflammatory disease of the nasal cavity and paranasal sinuses: an interesting differential diagnostic problem.
The authors present a case of synchronous manifestation of a myeloproliferative--extramedullary plasmocytoma--and a chronic inflammatory disease of the nose and the paranasal sinuses. They emphasise the importance of imaging techniques and immunohistochemistry in the differential diagnosis. They discuss on the basis of published articles the new classification, clinical manifestations, diagnostic and therapeutical approaches of this tumour belonging to the group of monoclonal gammopathies, which originates from an abnormal proliferation of mature B-lymphocytes, and is a rarity in the literature even nowadays.
University of Szeged, Department of Otorhinolaryngology, Head and Neck Surgery, Szeged, Hungary. office@orl.szote.u-szeged.hu
Iván
I
László
Vass
V
Gábor
Bella
B
Zsolt
Tiszlavicz
T
László
Jóri
J
József
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000175:diagnosis* / Q000532:radiotherapy; D009668:Nose Diseases / Q000175:diagnosis* / Q000532:radiotherapy; D009669:Nose Neoplasms / Q000175:diagnosis; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000532:radiotherapy; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis; D010954:Plasmacytoma / Q000175:diagnosis; D014057:Tomography, X-Ray Computed