Lymphatic filariasis: patients and the global elimination programme.
The defining images of lymphatic filariasis are the horrendous disfigurements of lymphoedema, elephantiasis and hydrocele. These clinical presentations, although obviously important and life changing, are not, however, the only outcomes of this wide-spread filarial infection. The other effects of the disease range from severe, acute but short-term bouts of sickness to psychological impairment, poverty and family hardship. It is important to support cases of the disease through all means available, such as reparative hydrocelectomy, hygiene training and facilitation, and the provision of adequate chemotherapy. Although only a minority of the residents in any endemic community is affected with the severe clinical manifestations of this parasitic infection, these cases are central to, and important advocates for, the current global effort to eliminate the infection through mass drug administrations (MDA). Their clinical improvement acts as an important catalyst for the general population and encourages high compliance in the MDA. This communication discusses the central role that filariasis patients have played in the Tanzania Lymphatic Filariasis Elimination Programme to date, and covers some of the clinical successes achieved in the past 10 years. The abolition of the clinical manifestations of filarial infection remains the ultimate goal of the Global Programme to Eliminate Lymphatic Filariasis, and maintaining a focus on the affected individuals and their clinical condition is vital to that programme's overall success.
Mackenzie
C D
CD
Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA. mackenz8@msu.edu
Lazarus
W M
WM
Mwakitalu
M E
ME
Mwingira
U
U
Malecela
M N
MN
D000818:Animals; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000523:psychology / Q000534:rehabilitation; D005260:Female; D005369:Filaricides / Q000191:economics / Q000627:therapeutic use*; D014943:Global Health; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008209:Lymphedema / Q000188:drug therapy / Q000517:prevention & control / Q000523:psychology; D008297:Male; D008393:Marriage / Q000523:psychology; D016730:Program Development; D011788:Quality of Life; D013636:Tanzania; D006848:Testicular Hydrocele / Q000188:drug therapy / Q000523:psychology; D016896:Treatment Outcome; D014958:Wuchereria bancrofti
D005369:Filaricides