Sclerosing angiomatoid nodular transformation of the spleen: CT, MR, PET, and ⁹⁹(m)Tc-sulfur colloid SPECT CT findings with gross and histopathological correlation.
Sclerosing angiomatoid nodular transformation (SANT) is a benign, proliferative vascular lesion affecting the spleen. Few reports detailing the cross sectional and PET appearance of this lesion are available, and the lesion's behavior with ⁹⁹(m)Tc-sulfur colloid scintigraphy is previously unreported. Sclerosing nodular transformation of the spleen shows increased tracer accumulation on positron emission tomography, and a central scar-like appearance with an enhancing capsule and radiating septae on CT and MR studies that reflects the gross and histopathological features of the lesion may be visible. An understanding of this pathological finding may allow prospective recognition of the sclerosing nodular transformation of the spleen on cross sectional imaging studies.
Thacker
Curtis
C
Scottsdale Medical Imaging, Ltd, AZ 85258, USA.
Korn
Ronald
R
Millstine
John
J
Harvin
Howard
H
Van Lier Ribbink
Jeffrey A
JA
Gotway
Michael B
MB
D000369:Aged, 80 and over; D000798:Angiomatosis / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012598:Sclerosis / Q000175:diagnosis / Q000473:pathology; D013156:Splenectomy; D013158:Splenic Diseases / Q000175:diagnosis* / Q000473:pathology; D013671:Technetium Tc 99m Sulfur Colloid; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D013671:Technetium Tc 99m Sulfur Colloid