EXPERIMENTAL GRANULOPENIA, DUE TO BACTERIAL TOXINS ELABORATED IN VIVO.
Pyogenic organisms, under conditions simulating a focal infection, are capable of producing in rabbits a granulopenia which may allow generalized infection and death. It is suggested that agranulocytosis in man is due to the action of leucocidin, rather than to a specific microorganism.
Dennis
E W
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Department of Bacteriology, School of Medicine, American University of Beirut, Beirut, Syria.