Acute ingestion of resistant starch reduces food intake in healthy adults.
Resistant starch (RS), a non-viscous dietary fibre, may have postprandial effects on appetite regulation and metabolism, although the exact effects and mechanisms are unknown. An acute randomised, single-blind crossover study, aimed to determine the effects of consumption of 48 g RS on appetite compared to energy and available carbohydrate-matched placebo. Twenty young healthy adult males consumed either 48 g RS or the placebo divided equally between two mixed meals on two separate occasions. Effects on appetite were assessed, using an ad libitum test meal and 24-h diet diaries for energy intake, and using visual analogue scales for subjective measures. Changes to postprandial glucose, insulin and C-peptide were also assessed. There was a significantly lower energy intake following the RS supplement compared to the placebo supplement at both the ad libitum test meal (5241 (sem 313) v. 5606 (sem 345) kJ, P = 0.033) and over the 24 h (12 603 (sem 519) v. 13 949 (sem 755) kJ, P = 0.044). However, there was no associated effect on subjective appetite measures. Postprandial plasma glucose concentrations were not significantly different between supplements, but there was a significantly lower postprandial insulin response following the RS supplement (P = 0.029). The corresponding C-peptide concentrations were not significantly different, although the ratio of C-peptide to insulin was higher following the RS supplement compared to placebo (P = 0.059). These results suggest that consumption of 48 g RS, over a 24-h period, may be useful in the management of the metabolic syndrome and appetite. Further studies are required to determine the exact mechanisms.
Diabetes and Endocrinology, Postgraduate Medical School, University of Surrey, Guildford, Surrey GU2 7WG, UK. m.robertson@surrey.ac.uk
Caroline L
CL
Bodinham
Gary S
GS
Frost
M Denise
MD
Robertson
D000328:Adult; D001066:Appetite; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002096:C-Peptide / Q000097:blood; D018592:Cross-Over Studies; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004043:Dietary Fiber / Q000008:administration & dosage*; D004063:Digestion; D004435:Eating; D002149:Energy Intake; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D010919:Placebos; D013213:Starch / Q000008:administration & dosage* / Q000378:metabolism
D001786:Blood Glucose; D002096:C-Peptide; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D007328:Insulin; D010919:Placebos; D013213:Starch