PURE CULTIVATION OF SPIROCHAETA PHAGEDENIS (NEW SPECIES), A SPIRAL ORGANISM FOUND IN PHAGEDENIC LESIONS ON HUMAN EXTERNAL GENITALIA.
1. A hitherto undescribed spiral organism has been isolated in pure culture from a case of mild phagedenic ulcer on the external genitalia of a woman. For this organism the name Spirochoeta phagedenis is proposed. 2. Spirochoeta phagedenis is a strict anaerobe and grows in the presence of fresh tissue in ascitic agar. It produces no apparent change in the media, but a somewhat offensive odor develops in the culture tube. 3. Spirochoeta phagedenis incites a slight inflammatory reaction in the skin of a Macacus rhesus monkey and in the skin and testicles of rabbits. 4. Its etiological relation to the phagedenic lesions on the external genitalia has not yet been determined.
Noguchi
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Laboratories of The Rockefeller Institute for Medical Research, New York.