Quantitation of respiratory viruses in relation to clinical course in children with acute respiratory tract infections.
Quantitation of respiratory viruses by PCR could potentially aid in clinical interpretation of PCR results. We conducted a study in children admitted with acute respiratory tract infections to study correlations between the clinical course of illness and semiquantitative detection of 14 respiratory viruses. Clinical improvement was associated with reduction of viral quantity after 3 days of hospitalization.
Jansen
Rogier R
RR
Department of Medical Microbiology, Academical Medical Centre, University of Amsterdam, room L1-245, Meibergdreef 9, 1105 AZ Amsterdam, TheNetherlands. R.R.Jansen@amc.uva.nl
Schinkel
Janke
J
Dek
Irene
I
Koekkoek
Sylvie M
SM
Visser
Caroline E
CE
de Jong
Menno D
MD
Molenkamp
Richard
R
Pajkrt
Dasja
D
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009305:Nasopharynx / Q000821:virology*; D016133:Polymerase Chain Reaction / Q000379:methods; D012141:Respiratory Tract Infections / Q000473:pathology* / Q000821:virology*; D012720:Severity of Illness Index; D013223:Statistics as Topic; D019562:Viral Load; D014777:Virus Diseases / Q000473:pathology* / Q000821:virology*; D014780:Viruses / Q000302:isolation & purification*