Scanning fiber angle-resolved low coherence interferometry.
We present a fiber-optic probe for Fourier-domain angle-resolved low coherence interferometry for the determination of depth-resolved scatterer size. The probe employs a scanning single-mode fiber to collect the angular scattering distribution of the sample, which is analyzed using the Mie theory to obtain the average size of the scatterers. Depth sectioning is achieved with low coherence Mach-Zehnder interferometry. In the sample arm of the interferometer, a fixed fiber illuminates the sample through an imaging lens and a collection fiber samples the backscattered angular distribution by scanning across the Fourier plane image of the sample. We characterize the optical performance of the probe and demonstrate the ability to execute depth-resolved sizing with subwavelength accuracy by using a double-layer phantom containing two sizes of polystyrene microspheres.
Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA.
Yizheng
Y
Zhu
Neil G
NG
Terry
Adam
A
Wax
D004867:Equipment Design; D005336:Fiber Optic Technology; D005583:Fourier Analysis; D006801:Humans; D007368:Interferometry / Q000379:methods*; D055100:Optical Fibers; D055095:Optics and Photonics; D019047:Phantoms, Imaging; D012031:Refractometry / Q000379:methods; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012984:Software; D013053:Spectrophotometry / Q000379:methods