THE EFFECTS OF BLOOD LOSS AND BLOOD DESTRUCTION UPON THE ERYTHROID CELLS IN THE BONE MARROW OF RABBITS.
The relative proportion of the various sorts of erythroid cells of the bone marrow has been determined after acute and chronic hemorrhage and after damage to the marrow with acetyl phenylhydrazine. The normal erythroid pattern shows megaloblasts and erythroblasts in the lowest percentage, then normoblasts, reticulocytes, and mature erythrocytes respectively, in increasing proportions. All three states studied show an increasing "shift to the left" up to a condition after acetyl phenylhydrazine, in which the erythroblasts and megaloblasts exceed the mature erythrocytes. The marrow pattern finds direct expression in terms of the cells of the blood.
Lilly Laboratory for Clinical Research, Indianapolis City Hospital, and the Department of Medicine, Indiana University School of Medicine, Indianapolis.
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Steele