[Perioperative antiplatelet therapy of patients with coronary stents].
The most feared complication after coronary stent implantation is the acutely occurring stent thrombosis, which usually leads to a myocardial infarction with its relatively high mortality. Dual antiplatelet therapy with acetylsalicylic acid and clopidogrel is currently the standard therapy after coronary stent implantation to prevent a life-threatening stent thrombosis. Surgery appears to increase the risk of stent thrombosis, myocardial infarction, and death, particularly when patients undergo surgery early after stent implantation. The incidence of complications is further increased when dual-antiplatelet therapy is discontinued preoperatively. This article reviews the current data of perioperative problems in patients after percutaneous coronary intervention.
HerzZentrum Hirslanden Zentralschweiz, Klinik St. Anna, Luzern. tushar.chatterjee@hirslanden.ch
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T
Chatterjee
I
I
Akin
T C
TC
Rehders
A
A
Chatterjee
C
C
Schüpfer
C A
CA
Nienaber
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H
Ince
D000284:Administration, Oral; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D000077144:Clopidogrel; D015331:Cohort Studies; D003327:Coronary Disease / Q000628:therapy*; D006801:Humans; D015201:Meta-Analysis as Topic; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects; D013927:Thrombosis / Q000209:etiology / Q000517:prevention & control*; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D013997:Time Factors
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin