Complete genome sequence of Anaplasma marginale subsp. centrale.
Anaplasma marginale subsp. centrale is a naturally attenuated subtype that has been used as a vaccine for a century. We sequenced the genome of this organism and compared it to those of virulent senso stricto A. marginale strains. The comparison markedly narrows the number of outer membrane protein candidates for development of a safer inactivated vaccine and provides insight into the diversity among strains of senso lato A. marginale.
Animal Diseases Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Pullman, Washington 99164, USA.
David R
DR
Herndon
Guy H
GH
Palmer
Varda
V
Shkap
Donald P
DP
Knowles
Kelly A
KA
Brayton
D042322:Anaplasma marginale / Q000235:genetics*; D016680:Genome, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data