Long-term follow-up of craniofacial alterations in juvenile idiopathic arthritis.
OBJECTIVE
To investigate changes in the craniofacial skeleton in relation to the changes in condylar alterations that occur during long-term follow-up in patients with juvenile idiopathic arthritis.


METHODS
Temporomandibular joint (TMJ) involvement is defined as a condylar alteration that is observed on the orthopantomogram. Lateral cephalograms were used to determine linear and angular measurements.


RESULTS
Seventy of 97 patients from the initial study cohort were included, with a mean follow-up of 68 months. The overall prevalence of condylar alterations and posterior rotation of the mandible decreased; however, the prevalence of retrognathia remained the same. Patients showed improvement in the degree of retrognathia and posterior rotation (40% ANB, 51% OP-SN, and 44% GO-GN-SN). Improvement in the degree of retrognathia was seen more often in patients with improved condylar alterations than in patients with persistent alterations and in those without alterations (50%, 33%, and 28%, respectively). The degree of posterior rotation improved almost equally in patients without TMJ involvement and in patients with improved condylar alterations (57% and 50% by OP-SN, and 67% and 38% GO-GN-SN, respectively) and did not improve in patients with stable persistent alterations.


CONCLUSIONS
Both condylar and craniofacial alterations can improve in patients with juvenile idiopathic arthritis.
Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands. m.twilt@erasmusmc.nl
Marinka
M
Twilt
Alcuin J M
AJ
Schulten
Birte
B
Prahl-Andersen
Lisette W A
LW
van Suijlekom-Smit
D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications*; D002508:Cephalometry; D002648:Child; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008335:Mandibular Condyle / Q000473:pathology*; D011862:Radiography, Panoramic; D063173:Retrognathia / Q000145:classification / Q000209:etiology; D012399:Rotation; D013705:Temporomandibular Joint Disorders / Q000150:complications*; D055815:Young Adult