Focal liver lesions hyperintense on T1-weighted magnetic resonance images.
This article reviews focal liver lesions hyperintense on T1-weighted magnetic resonance (MR) images and describes the underlying etiologies associated with their T1 signal intensity. Although focal liver lesions are commonly detected because of their iso- or hypointensity on T1-weighted images, lesions (benign or malignant) may present with T1 hyperintensity when they contain T1 shortening elements--such as fat, hemorrhage, copper, melanin, and highly concentrated proteins. Our discussion includes the description of state-of-the-art T1-weighted MR sequences and the imaging features of lesions on pre- and postcontrast MR images that are characteristic for lesion composition and useful for making accurate diagnosis.
University of Pittsburgh Medical Center, Department of Radiology, 3362 Fifth Avenue, Pittsburgh, PA 15213, USA. furlana@upmc.edu
Alessandro
A
Furlan
Daniele
D
Marin
Kyongtae T
KT
Bae
Roberto
R
Lagalla
Francesco
F
Agnello
Massimo
M
Bazzocchi
Giuseppe
G
Brancatelli
D003287:Contrast Media; D003937:Diagnosis, Differential; D006801:Humans; D021621:Imaging, Three-Dimensional; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*
D003287:Contrast Media