Dimorphisms in the membrane-spanning domain of EPCR impact systemic coagulation.
Esmon
Charles T
CT
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001777:Blood Coagulation / Q000235:genetics*; D001778:Blood Coagulation Disorders / Q000235:genetics / Q000378:metabolism; D001779:Blood Coagulation Factors / Q000235:genetics / Q000378:metabolism*; D015536:Down-Regulation; D004730:Endothelium, Vascular / Q000378:metabolism*; D005786:Gene Expression Regulation; D006801:Humans; D011485:Protein Binding; D011956:Receptors, Cell Surface / Q000378:metabolism*; D012680:Sensitivity and Specificity; D018180:Thrombomodulin / Q000235:genetics / Q000378:metabolism*
D015415:Biomarkers; D001779:Blood Coagulation Factors; D011956:Receptors, Cell Surface; D018180:Thrombomodulin; C091963:activated protein C receptor