Diversity and origin of dengue virus serotypes 1, 2, and 3, Bhutan.
To determine the serotype and genotype of dengue virus (DENV) in Bhutan, we conducted phylogenetic analyses of complete envelope gene sequences. DENV-2 (Cosmopolitan genotype) predominated in 2004, and DENV-3 (genotype III) predominated in 2005-2006; these viruses were imported from India. Primary dengue infections outnumbered secondary infections, suggesting recent emergence.
Ministry of Health, Thimphu, Bhutan.
Tandin
T
Dorji
In-Kyu
IK
Yoon
Edward C
EC
Holmes
Sonam
S
Wangchuk
Tashi
T
Tobgay
Ananda
A
Nisalak
Piyawan
P
Chinnawirotpisan
Kanittha
K
Sangkachantaranon
Robert V
RV
Gibbons
Richard G
RG
Jarman
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000453:epidemiology* / Q000821:virology*; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D010802:Phylogeny; D012703:Serotyping; D055815:Young Adult