Confronting morphogen gradients: how important are they for growth?
Morphogens are crucial for regulating the patterning and the growth of organs. In the developing fly wing, graded distributions of the morphogens Decapentaplegic and Wingless are essential for tissue patterning, but when it comes to growth, evidence suggests that it may not be so.
Hamaratoglu
Fisun
F
Biozentrum der Universität Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland. hamaratoglu@unibas.ch
Basler
Konrad
K
Affolter
Markus
M
D000818:Animals; D019521:Body Patterning; D029721:Drosophila Proteins / Q000502:physiology; D004331:Drosophila melanogaster / Q000196:embryology*; D009024:Morphogenesis; D051155:Wnt1 Protein / Q000502:physiology
D029721:Drosophila Proteins; D051155:Wnt1 Protein; C064196:dpp protein, Drosophila; C074622:wg protein, Drosophila