A case of luteinizing thecoma with sclerosing peritonitis: revisiting a link with anti-epileptic drugs.
Luteinizing thecoma with sclerosing peritonitis (LTSP) is a rare ovarian tumor of unclear etiology and pathogenesis. The diagnostic entity was proposed in 1994, but a number of earlier reports described possible cases, and some suggested an association with anti-epileptic drugs (AEDs). In presenting a new case we review the literature of previous cases to evaluate the possibility of such a link. When cases in reproductively immature patients are considered, evidence for an association between LTSP and AEDs is strongly suggested despite the rarity of the condition.
Nauen
David W
DW
Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. dwnauen@pitt.edu
Martin
Allison
A
Katz
Aviva
A
Cohen
Debra
D
Ranganathan
Sarangarajan
S
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D010051:Ovarian Neoplasms / Q000139:chemically induced* / Q000473:pathology; D010538:Peritonitis / Q000139:chemically induced* / Q000473:pathology; D012598:Sclerosis; D013798:Thecoma / Q000139:chemically induced* / Q000473:pathology
D000927:Anticonvulsants