TLR2 joins the interferon gang.
The induction of type I interferon is a critical checkpoint in antiviral immunity. Toll-like receptor 2 can unexpectedly induce type I interferon in the subset of inflammatory monocytes during infection with vaccinia virus.
Bauernfeind
Franz
F
Hornung
Veit
V
D000818:Animals; D007370:Interferon Type I / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D009000:Monocytes / Q000276:immunology*; D051195:Toll-Like Receptor 2 / Q000276:immunology* / Q000378:metabolism; D014615:Vaccinia / Q000276:immunology*; D014616:Vaccinia virus / Q000276:immunology
D007370:Interferon Type I; C493486:Tlr2 protein, mouse; D051195:Toll-Like Receptor 2