12-Hydroxystearic acid lipid tubes under various experimental conditions.
There is a growing interest for constructing supramolecular hollow tubes from amphiphilic molecules. Aqueous solutions of the ethanolamine salt of 12-hydroxystearic acid are known to form tubes of several tens of micrometers in length with a temperature-tunable diameter. However, the phase behavior of this system has not been fully studied. Herein, we report the variation of various physico-chemical parameters on the self-assembling properties of this system. The effects of the ionic strength, ethanol, doping with other lipids, pH, concentration, and the fatty acid/ethanolamine molar ratio R were investigated by both phase-contrast microscopy and DSC. We observed the formation of tubes in a wide range of parameters. For instance, the molar ratio R can be modified from 2/3 to 5/2 without altering the formation of tubes. In some but not all cases, the tube diameter still varied with temperature. These findings show that tubes form under various experimental conditions. This should increase the interest in producing such self-assemblies from low-cost fatty acids.
Fameau
Anne-Laure
AL
UR1268 Biopolymères Interactions Assemblages Inra, rue de la Géraudière, 44316 Nantes, France.
Houinsou-Houssou
Bérénice
B
Novales
Bruno
B
Navailles
Laurence
L
Nallet
Frédéric
F
Douliez
Jean-Paul
JP
D006863:Hydrogen-Ion Concentration; D008055:Lipids / Q000737:chemistry*; D044367:Phase Transition; D013229:Stearic Acids / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry; D014867:Water / Q000737:chemistry
D008055:Lipids; D013229:Stearic Acids; D013501:Surface-Active Agents; D014867:Water