Fertility issues in women with diabetes.
Diabetes mellitus Type 1 and Type 2 should be considered in the differential diagnosis of menstrual abnormalities and infertility. The reproductive period of diabetic women may be reduced due to delayed menarche and premature menopause. During the reproductive years, diabetes has been associated with menstrual abnormalities, such as oligomenorrhea and secondary amenorrhea. It was found that better glycemic control and prevention of diabetic complications improves these irregularities and increases fertility rates close to those that are seen in the general population. Women with persistent menstrual abnormalities despite adequate treatment need to be approached by broader evaluation, which will include the examination of the hypothalamic-pituitary-ovarian axis and the hormonal status, presence of autoimmune thyroid disease and antiovarian autoantibodies, and hyperandrogenism.
Livshits
Anna
A
Department of Obstetrics & Gynecology, Chaim Sheba Medical Center, 52621 Tel-Hashomer, Israel.
Seidman
Daniel S
DS
D001327:Autoimmune Diseases / Q000150:complications; D001786:Blood Glucose; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000517:prevention & control; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D008593:Menopause; D008599:Menstruation Disturbances / Q000150:complications*; D009765:Obesity / Q000150:complications; D012735:Sexual Dysfunction, Physiological / Q000150:complications
D001786:Blood Glucose