Non-steroidal anti-inflammatory drugs in orthopaedic and perioperative practice.
Non-steroidal anti-inflammatory drugs are powerful and effective anti-inflammatory, analgesic and anti-pyretic drugs. They are routinely used in orthopaedic conditions and in the perioperative setting. They are however associated with potentially life-threatening side-effects and it is important to appreciate these before these medicines are administered. There is evidence suggesting that these drugs adversely affect bone formation, and this has implications for their use in patients with fractures and other pathologies that involve bone remodelling.
Academic Orthopaedic Registrar, University College London Institute of Orthopaedic and Musculoskeletal Research, Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, UK. wasimkhan@doctors.org.uk
Wasim
W
Khan
Mamun
M
Al-Rashid
David R
DR
Marsh
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D009985:Orthopedics; D019990:Perioperative Care
D000894:Anti-Inflammatory Agents, Non-Steroidal