The Mediterranean red alga Asparagopsis: a source of compounds against Leishmania.
Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds. Extracts from both species revealed remarkable antiprotozoal activity against Leishmania, revealing such algae as a great source of natural antiprotozoal products.
Genovese
Giuseppa
G
Department of Life Sciences M. Malpighi-Botany, University of Messina, Salita Sperone, 31, 98166 Messina, Italy.
Tedone
Laura
L
Hamann
Mark T
MT
Morabito
Marina
M
D000666:Amphotericin B / Q000008:administration & dosage / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D007558:Italy; D007891:Leishmania / Q000187:drug effects*; D007896:Leishmaniasis / Q000188:drug therapy; D008522:Mediterranean Sea; D010419:Pentamidine / Q000008:administration & dosage / Q000494:pharmacology; D000461:Rhodophyta / Q000737:chemistry*; D014344:Trypanocidal Agents / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*
D014344:Trypanocidal Agents; D010419:Pentamidine; D000666:Amphotericin B