Prognostic factors in non-exertional heatstroke.
OBJECTIVE
To identify the prognostic factors associated with mortality in heat-related illness.


METHODS
Multi-center observational cohort-study in 16 emergency departments (ED) belonging to the teaching hospital network of the Paris area. The cohort comprised all patients admitted to one of the EDs during the August 2003 heat wave in Paris and having a core temperature >38.5 degrees C. Baseline clinical and biological data in ED, patient's course and 1-year survival rate were recorded. Potential prognostic factors associated with death were assessed by Cox proportional-hazards analysis.


RESULTS
A total of 1,456 patients were included. Mean age was 79 +/- 19 years. Critically ill conditions were noted in 391 patients (27%), but only 72 (5%) were admitted into an intensive care unit. The survival rate was 57% at 1 year as compared to an expected 90% (P < 0.001). Nine independent prognostic factors were identified: previous treatment with diuretics, living in an institution, age >80 years, cardiac disease, cancer, core temperature >40 degrees C, systolic arterial pressure <100 mmHg, Glasgow coma scale <12 and transportation to hospital by ambulance. We defined three risk groups: low, intermediate and high risk, with a 1-year survival rate of 85, 61 and 18%, respectively.


CONCLUSIONS
We observed a low survival rate and developed a risk score based on easily obtained variables that may be useful to clinicians managing casualties from future heat waves.
Hausfater
Pierre
P
Emergency Department, Centre Hospitalo-Universitaire(CHU) Pitié-Salpêtrière Assistance-Publique Hôpitaux de Paris, UPMC Univ Paris 06, Paris, France. pierre.hausfater@psl.aphp.fr
Megarbane
Bruno
B
Dautheville
Sandrine
S
Patzak
Anabella
A
Andronikof
Marc
M
Santin
Aline
A
André
Stéphanie
S
Korchia
Ludovic
L
Terbaoui
Nabila
N
Kierzek
Gérald
G
Doumenc
Benoît
B
Leroy
Christophe
C
Riou
Bruno
B
D000368:Aged; D001831:Body Temperature; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D008297:Male; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology*; D011379:Prognosis; D011446:Prospective Studies; D015996:Survival Rate