Hemispheric synchronized sounds and perioperative analgesic requirements.
BACKGROUND
Data on the effect of Hemisync sounds on perioperative analgesic requirements are scant.


METHODS
We randomized surgical outpatients into a treatment group that received Hemisync sounds (n = 20), a music group that received music (n = 20), and a control group that had a blank cassette tape (n = 20). All subjects underwent a controlled standardized propofol-nitrous-vecuronium and fentanyl general anesthesia.


RESULTS
The treatment group had significantly reduced intraoperative fentanyl consumption (P < 0.05). Postoperatively, pain visual analog scale scores were significantly lower in the Hemisync group at 1 h (P = 0.02) and 24 h (P = 0.005). Subjects in the Hemisync group were also discharged earlier (P = 0.048).


CONCLUSIONS
The use of Hemisync sounds before and during general anesthesia reduces intraoperative analgesic requirements, postoperative pain scores, and discharge time.
Department of Anesthesiology, Yale University School of Medicine, USA.
Susan
S
Dabu-Bondoc
Nalini
N
Vadivelu
Judy
J
Benson
Danielle
D
Perret
Zeev N
ZN
Kain
D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000700:Analgesics / Q000008:administration & dosage* / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D000768:Anesthesia, General; D003344:Cortical Synchronization; D004311:Double-Blind Method; D023381:Endpoint Determination; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy* / Q000517:prevention & control; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control; D019990:Perioperative Care; D055815:Young Adult
D000700:Analgesics; D000701:Analgesics, Opioid; D005283:Fentanyl