Perianal presentation of Langerhans cell histiocytosis in children.
Langerhans cell histiocytosis, previously known as histiocytosis X, is a disease whose clinical presentation varies. Although it is uncommon, Langerhans cell histiocytosis may involve the perianal region. We report the case of a 2-year-old boy who presented with perianal ulcerated vegetative lesions and seborrheic dermatitis of the scalp. Biopsy of the lesions showed Langerhans cell histiocytosis. This patient did not have any other organ involvement, which is rare. The outcome was favourable with vinblastine and corticoids.
Department of Pediatrics B, Children's Hospital of Tunis, Boulevard 9 avril, 1007 Jabbary, Bab Saadoun, Tunis, Tunisia. faten.tinsa@hotmail.fr
F
F
Tinsa
I
I
Brini
M
M
Kharfi
K
K
Mrad
K
K
Boussetta
S
S
Bousnina
D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001004:Anus Diseases / Q000188:drug therapy / Q000209:etiology*; D002675:Child, Preschool; D012628:Dermatitis, Seborrheic / Q000188:drug therapy / Q000209:etiology; D005938:Glucocorticoids / Q000627:therapeutic use; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014747:Vinblastine / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D005938:Glucocorticoids; D014747:Vinblastine; D011241:Prednisone