[Subcutaneous implantation of embryonic skin cells to construct a model of hair development in nude mice].
OBJECTIVE
To observe the hair development after subcutaneous implantation of embryonic skin cells in nude mice, and construct a model of hair development.


METHODS
Dermal and epidermal cells isolated from embryonic mouse skin were mixed at a given ratio and injected subcutaneously in nude mice, and hair formation after the implantation was observed under a microscope.


RESULTS
Formation of the hair follicles and fibers under the skin of the recipient nude mice and emergence of the hair shaft were observed microscopically.


CONCLUSIONS
Embryonic skin cells be used to construct a complete model of hair development after implantation in vivo.
Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. doctor.cmj13520 @yahoo.com.cn
Ming-juan
MJ
Chen
Zhi-qi
ZQ
Hu
Ting
T
Tan
Xi-jin
XJ
Sun
Yong
Y
Miao
D000818:Animals; D017690:Cell Transplantation; D002478:Cells, Cultured; D020405:Dermis / Q000166:cytology / Q000637:transplantation; D004622:Embryo, Mammalian; D000078404:Epidermal Cells; D004817:Epidermis / Q000637:transplantation; D006197:Hair / Q000254:growth & development*; D051379:Mice; D008810:Mice, Inbred C57BL; D008819:Mice, Nude; D023421:Models, Animal; D012867:Skin / Q000166:cytology*