Salmonella colonisation of laying hens following vaccination with killed and live attenuated commercial Salmonella vaccines.
The aim of this study was to determine the efficacy of a killed Salmonella vaccine and three live vaccines in preventing caecal colonisation of Hy-line Brown pullets by Salmonella Enteritidis PT 4. The lowest number of Salmonella-positive birds following the largest challenge (10(8) cfu) was recorded for live vaccine 1. However, birds treated with the killed vaccine had a significantly lower number of salmonellae in their caeca compared with both the control group and the other vaccine groups (P<0.05).
Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5LX. robert.atterbury@nottingham.ac.uk
R J
RJ
Atterbury
J J
JJ
Carrique-Mas
R H
RH
Davies
V M
VM
Allen
D000818:Animals; D002432:Cecum / Q000382:microbiology; D002645:Chickens; D015169:Colony Count, Microbial / Q000662:veterinary; D004334:Drug Administration Schedule; D037901:Euthanasia, Animal; D005260:Female; D011201:Poultry Diseases / Q000517:prevention & control*; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D022562:Salmonella Vaccines / Q000008:administration & dosage / Q000592:standards*; D012477:Salmonella enteritidis / Q000254:growth & development / Q000276:immunology*; D006113:United Kingdom; D014613:Vaccines, Attenuated / Q000592:standards; D015164:Vaccines, Inactivated / Q000592:standards
D022562:Salmonella Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated