Retrospective diagnosis of congenital cytomegalovirus infection at a school for the deaf by using preserved dried umbilical cord.
A retrospective diagnosis of congenital cytomegalovirus infection was made for 3 of 26 students (12%) with either bilateral profound or severe sensorineural hearing loss at a School for the Deaf in Japan by detecting viral DNA with real-time polymerase chain reaction from dried umbilical cords that had been preserved at home.
Department of Pediatrics, Nagasaki University Hospital, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Masato
M
Tagawa
Hideo
H
Tanaka
Masako
M
Moriuchi
Hiroyuki
H
Moriuchi
D000293:Adolescent; D002648:Child; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005312:Fetal Blood / Q000821:virology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D015997:Neonatal Screening; D019986:Persons with Hearing Disabilities; D015995:Prevalence; D012189:Retrospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D013334:Students; D013997:Time Factors
D004279:DNA, Viral