Ring-extended derivatives of gramicidin S with furanoid sugar amino acids in the turn region have enhanced antimicrobial activity.
Leiden Institute of Chemistry, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.
Annemiek D
AD
Knijnenburg
Emile
E
Spalburg
Albert J
AJ
de Neeling
Roos H
RH
Mars-Groenendijk
Daan
D
Noort
Gijsbert M
GM
Grotenbreg
Gijsbert A
GA
van der Marel
Herman S
HS
Overkleeft
Mark
M
Overhand
D000596:Amino Acids / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002241:Carbohydrates / Q000737:chemistry; D004912:Erythrocytes / Q000187:drug effects; D006096:Gramicidin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D017433:Protein Structure, Secondary
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D002241:Carbohydrates; D006096:Gramicidin