Cardiac tumor in juvenile onset Behçet's disease: case report and review of the literature.
Behçet's disease is a chronic multisystemic inflammatory disorder characterized by orogenital ulcerations, uveitis, and occasional cardiac involvement. This report describes an atypical presentation of pediatric Behçet's disease with pulmonary emboli and a cardiac mass. A 16-year-old boy with a 2-year history of oral ulcers presented with weight loss, fever, joint pain, and a large tumor adhering to the free wall of the heart's right ventricle. Surgical biopsy demonstrated endomyocarditis with thrombus formation and led to the diagnosis. At the 2-year follow-up evaluation, intracardiac thrombus and pulmonic emboli had not recurred. Symptom control with immunosuppressive therapy was good.
Department of Pediatric Cardiology, Penn State Hershey Children's Hospital, Mailbox HP14, 500 University Drive, Hershey, PA 17033, USA.
Elizabeth E
EE
Adams
Vincent P R
VP
Aluquin
C April
CA
Bingham
James R
JR
Stone
Linda B
LB
Pauliks
D000293:Adolescent; D001528:Behcet Syndrome / Q000150:complications* / Q000473:pathology / Q000628:therapy; D004452:Echocardiography; D004696:Endocarditis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy