Changes in multidrug resistance of enteric bacteria following an intervention to reduce antimicrobial resistance in dairy calves.
An intervention study was conducted to determine whether discontinuing the feeding of milk replacer medicated with oxytetracycline and neomycin to preweaned calves reduced antimicrobial resistance in Salmonella, Campylobacter, and Escherichia coli bacteria. Results demonstrated that the intervention did reduce multidrug resistance in these bacteria but that other factors also influenced multidrug resistance.
Kaneene
John B
JB
Center for Comparative Epidemiology, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824-1314, USA. kaneene@cvm.msu.edu
Warnick
Lorin D
LD
Bolin
Carole A
CA
Erskine
Ronald J
RJ
May
Katherine
K
Miller
Roseann
R
D000821:Animal Feed; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D002167:Campylobacter / Q000187:drug effects; D003612:Dairying; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects; D005243:Feces / Q000382:microbiology*; D005260:Female; D006090:Gram-Negative Bacteria / Q000145:classification / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D009355:Neomycin / Q000737:chemistry / Q000494:pharmacology; D010118:Oxytetracycline / Q000737:chemistry / Q000494:pharmacology; D012475:Salmonella / Q000187:drug effects
D000900:Anti-Bacterial Agents; D009355:Neomycin; D010118:Oxytetracycline