Chondroid syringoma with tyrosine crystals: case report and review of the literature.
Chondroid syringoma (CS) is a relatively rare cutaneous mixed tumor arising from sweat glands. It usually presents in the head and neck area as an asymptomatic, slow-growing, firm, circumscribed, lobulated nodule within the dermis or subcutaneous fat. CSs share morphologic similarities with their salivary gland counterparts, pleomorphic adenomas (benign mixed tumors). Although the presence of tyrosine-rich crystalloids in mixed tumors of the salivary gland is well recognized, to our knowledge, this finding has not been previously described in mixed tumors of the skin. We report a case of tyrosine crystalline structures in a CS and review the pertinent literature.
Department of Pathology and Laboratory Medicine, University of California Los Angeles, USA.
Monica B
MB
Constantinescu
Jessica B
JB
Chan
David S
DS
Cassarino
D000328:Adult; D003460:Crystallization; D005260:Female; D006801:Humans; D012867:Skin / Q000378:metabolism / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D018252:Syringoma / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D014443:Tyrosine / Q000378:metabolism*
D014443:Tyrosine