STUDIES ON THE RELATIONSHIP OF THE CHEMICAL CONSTITUENTS OF BLOOD AND CEREBROSPINAL FLUID.
1. If due allowance is made for the slow rate of elaboration of cerebrospinal fluid and for the time that it takes for newly formed fluid to emerge from a needle in the cistema, the amount of sugar, chloride, and non-protein nitrogen in the fluid seems to follow in a general way their concentrations in the blood stream. 2. It is equally evident, however, that for any substance other factors besides its concentration in the blood stream play a part in its distribution between blood and cerebrospinal fluid.
Department of Physiology of the Johns Hopkins Medical School and the Laboratory of Internal Medicine of the Henry Phipps Psychiatric Clinic of the Johns Hopkins Hospital, Baltimore.
L S
LS
Kubie
G M
GM
Shults