Neuroimaging demonstration of evolving small vessel ischemic injury in cerebral amyloid angiopathy.
OBJECTIVE
Cerebral amyloid angiopathy is a small to medium vasculopathy most commonly associated with symptomatic intracerebral hemorrhage and microbleeds. Summary of Case- We present a patient with cerebral microbleeds and likely amyloid angiopathy with evolving ischemic lesions visualized on diffusion-weighted imaging.


CONCLUSIONS
This case captures with serial MRI the evolving and dynamic nature of cerebral amyloid angiopathy and particularly illustrates the subclinical, yet progressive, ischemic aspects of this vasculopathic process.
Menon
Ravi S
RS
Department of Neurology and Stroke Center, Georgetown University, Washington, DC 20007, USA. ravi.menon@gunet.georgetown.edu
Kidwell
Chelsea S
CS
D001160:Arterioles / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D002545:Brain Ischemia / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D015984:Causality; D016657:Cerebral Amyloid Angiopathy / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D002536:Cerebral Arteries / Q000473:pathology* / Q000503:physiopathology; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D002985:Clinical Protocols; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D018450:Disease Progression; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D018810:Magnetic Resonance Angiography / Q000379:methods; D008297:Male; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010975:Platelet Aggregation Inhibitors