Synthesis and NMR properties of the first boron analogues of uracil.
Synthesis of 4-hydroxyborauracil and 4-hydroxy-3-methylborauracil, the first boron analogues of uracil, and comparison of their 1H and 13C NMR properties with those of uracil, are presented. The analyses of NMR-monitored boron compound-alcohol and boron compound-amine interactions pointed to the existence of sp3-hybridized, B,B-bis-methoxyborauracils and pyridine-/n-butylamine-borauracils ate-complexes in solution.
Rzeszów University of Technology, Faculty of Chemistry, Department of Biochemistry and Biotechnology, 6 Powstańców Warszawy Ave., 35-959 Rzeszów, Poland. tomruman@prz.edu.pl
Tomasz
T
Ruman
Karolina
K
Długopolska
Wojciech
W
Rode
D001895:Boron / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D014498:Uracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
C548923:4-hydroxy-3-methylborauracil; C548924:4-hydroxyborauracil; D014498:Uracil; D001895:Boron