Effect of chirality of L/D-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(alpha-amino acid)-thymidine dimers.
The chirality of the amide linker in dimer blocks was found to have a profound effect on the orientation of base stacking interactions as studied by CD and NMR spectroscopy.
Bagmare
Seema
S
Division of Organic Chemistry, National Chemical Laboratory, Pune 411008, India.
D'Costa
Moneesha
M
Kumar
Vaijayanti A
VA
D002942:Circular Dichroism; D019281:Dimerization; D005998:Glycine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011392:Proline / Q000737:chemistry*; D013237:Stereoisomerism; D013936:Thymidine / Q000737:chemistry*
D011392:Proline; D005998:Glycine; D013936:Thymidine