Silver-containing hydrofiber dressing is an effective adjunct in the treatment of pemphigus vulgaris.
Pemphigus vulgaris is a life-threatening autoimmune bullous dermatosis and its management represents a major challenge to medical teams. The primary treatments for pemphigus vulgaris are oral steroids and immunosuppressants, but topical approaches also play a role in disease management. Here, we report a patient with pemphigus vulgaris involving 62% of the total body surface area, with initial poor clinical response to systemic steroids and topical silver sulfadiazine therapy. However, a marked improvement in wound healing and decreased patient discomfort were observed after application of silver-containing hydrofiber dressings (Aquacel-Ag). Therefore, silver-containing hydrofiber dressings may offer an effective adjunct in the treatment of patients with pemphigus vulgaris with extensive skin involvement. Our encouraging experience with these dressing patches may be extended to manage other large exudation wounds.
Department of Dermatology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chieh-Shan
CS
Wu
Hui-Yu
HY
Hsu
Stephen Chu-Sung
SC
Hu
Hsiu-Hui
HH
Chiu
Gwo-Shing
GS
Chen
D000287:Administration, Topical; D002266:Carboxymethylcellulose Sodium / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy* / Q000503:physiopathology; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D014945:Wound Healing
D002266:Carboxymethylcellulose Sodium; D012837:Silver Sulfadiazine