Positron emission tomography correlates of visually-scored electroencephalographic waveforms during non-Rapid Eye Movement sleep.
Visually-scored, non-Rapid Eye Movement (REM) sleep electroencephalographic (EEG) waveform activity for each 30-s sleep scored epoch-including the number of sleep spindles, the number of K-complexes, and the percentage of delta waves occupying the epoch-was correlated with H(2)(15)O positron emission tomography. Sleep spindle correlations included positive correlations in the thalamus and right hippocampus. K-complex correlations included positive correlations in the frontomedian prefrontal cortex and cerebellum. Delta wave correlations included negative correlations in the thalamus, frontomedian prefrontal cortex, dorsal pons, and primary visual cortex. Each pattern of correlations may suggest a functional significance for these waveforms that relates to a waking outcome.
Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA. dante.picchioni@amedd.army.mil
Dante
D
Picchioni
William D S
WD
Killgore
Thomas J
TJ
Balkin
Allen R
AR
Braun
D000328:Adult; D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D002531:Cerebellum / Q000033:anatomy & histology / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography / Q000379:methods*; D005071:Evoked Potentials / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology; D006624:Hippocampus / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D011149:Pons / Q000033:anatomy & histology / Q000502:physiology; D049268:Positron-Emission Tomography / Q000379:methods*; D017397:Prefrontal Cortex / Q000033:anatomy & histology / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D012890:Sleep / Q000502:physiology*; D013788:Thalamus / Q000033:anatomy & histology / Q000502:physiology; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology; D014851:Wakefulness / Q000502:physiology; D055815:Young Adult