Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli.
The catabolism of phosphonic acids occurs in Escherichia coli by the carbon-phosphorus lyase pathway, which is governed by the 14-cistron phn operon. Here, several compounds are shown to accumulate in strains of E. coli with genetic blocks in various phn cistrons when the strains are fed with phosphonate.
Hove-Jensen
Bjarne
B
Department of Biology, University of Copenhagen, 5 Ole Maaløes Vej, DK-2200 Copenhagen N, Denmark. hove@mermaid.molbio.ku.dk
Rosenkrantz
Tina J
TJ
Zechel
David L
DL
Willemoës
Martin
M
D002855:Chromatography, Thin Layer; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D008190:Lyases / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D009876:Operon / Q000235:genetics / Q000502:physiology*; D063065:Organophosphonates / Q000378:metabolism*; D010761:Phosphorus Radioisotopes / Q000378:metabolism
D029968:Escherichia coli Proteins; D063065:Organophosphonates; D010761:Phosphorus Radioisotopes; D008190:Lyases; C051328:carbon-phosphorus lyase