THE THERAPEUTIC VALUE OF INTRAMUSCULAR DOSAGE OF TYPE I PNEUMOCOCCUS ANTISERA.
1. Intramuscular dosage of antipneumococcus sera in a standard dermal pneumococcic infection in rabbits is as effective as intravenous dosage provided the degree of blood stream invasion be not unusually high. 2. The immediate bactericidal effect of doses of serum given intramuscularly is equal to that of the same doses given intravenously in the cases of mild and moderately severe bacteremias. 3. The intramuscular method of serum administration in human beings with lobar pneumonia deserves a carefully controlled clinical trial.
Curphey
T J
TJ
Department of Pathology, University and Bellevue Hospital Medical College and the Simon Baruch Foundation for Research in Pneumonia, and the Bureau of Laboratories, Department of Health of the City of New York, New York.
Baruch
H B
HB