Hemispheric synchronized sounds and perioperative analgesic requirements.
BACKGROUND
Data on the effect of Hemisync sounds on perioperative analgesic requirements are scant.


METHODS
We randomized surgical outpatients into a treatment group that received Hemisync sounds (n = 20), a music group that received music (n = 20), and a control group that had a blank cassette tape (n = 20). All subjects underwent a controlled standardized propofol-nitrous-vecuronium and fentanyl general anesthesia.


RESULTS
The treatment group had significantly reduced intraoperative fentanyl consumption (P < 0.05). Postoperatively, pain visual analog scale scores were significantly lower in the Hemisync group at 1 h (P = 0.02) and 24 h (P = 0.005). Subjects in the Hemisync group were also discharged earlier (P = 0.048).


CONCLUSIONS
The use of Hemisync sounds before and during general anesthesia reduces intraoperative analgesic requirements, postoperative pain scores, and discharge time.
Dabu-Bondoc
Susan
S
Department of Anesthesiology, Yale University School of Medicine, USA.
Vadivelu
Nalini
N
Benson
Judy
J
Perret
Danielle
D
Kain
Zeev N
ZN
D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000700:Analgesics / Q000008:administration & dosage* / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D000768:Anesthesia, General; D003344:Cortical Synchronization; D004311:Double-Blind Method; D023381:Endpoint Determination; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy* / Q000517:prevention & control; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control; D019990:Perioperative Care; D055815:Young Adult
D000700:Analgesics; D000701:Analgesics, Opioid; D005283:Fentanyl