No brain, no pain: does the injured brain stack up opioids?
Christine
C
Dictus
Oliver W
OW
Sakowitz
D018528:ATP-Binding Cassette Transporters / Q000502:physiology; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001812:Blood-Brain Barrier / Q000502:physiology*; D001921:Brain / Q000378:metabolism*; D002543:Cerebral Hemorrhage / Q000134:cerebrospinal fluid*; D016292:Procedural Sedation; D003422:Critical Care; D004305:Dose-Response Relationship, Drug; D016489:Head Injuries, Closed / Q000134:cerebrospinal fluid*; D006801:Humans; D015850:Interleukin-6 / Q000134:cerebrospinal fluid; D008657:Metabolic Clearance Rate / Q000502:physiology; D009020:Morphine / Q000008:administration & dosage / Q000493:pharmacokinetics*; D009022:Morphine Derivatives / Q000134:cerebrospinal fluid*; D013345:Subarachnoid Hemorrhage / Q000134:cerebrospinal fluid*
D018528:ATP-Binding Cassette Transporters; D000701:Analgesics, Opioid; D015850:Interleukin-6; D009022:Morphine Derivatives; C035349:morphine-6-glucuronide; D009020:Morphine; C018108:morphine-3-glucuronide