Catalytic enantioselective boron conjugate addition to cyclic carbonyl compounds: a new approach to cyclic beta-hydroxy carbonyls.
The highly enantioselective conjugate boration of six-membered and seven-membered cyclic enones and unsaturated esters was achieved by the use of a copper-(R,S)-Taniaphos complex with up to 99% ee under optimal conditions.
Department of Chemistry and Institute of Basic Science, Sungkyunkwan University, Suwon 440-746, Korea.
Xinhui
X
Feng
Jaesook
J
Yun