TriTrypDB: a functional genomic resource for the Trypanosomatidae.
TriTrypDB (http://tritrypdb.org) is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs. TriTrypDB is a collaborative project, utilizing the GUS/WDK computational infrastructure developed by the Eukaryotic Pathogen Bioinformatics Resource Center (EuPathDB.org) to integrate genome annotation and analyses from GeneDB and elsewhere with a wide variety of functional genomics datasets made available by members of the global research community, often pre-publication. Currently, TriTrypDB integrates datasets from Leishmania braziliensis, L. infantum, L. major, L. tarentolae, Trypanosoma brucei and T. cruzi. Users may examine individual genes or chromosomal spans in their genomic context, including syntenic alignments with other kinetoplastid organisms. Data within TriTrypDB can be interrogated utilizing a sophisticated search strategy system that enables a user to construct complex queries combining multiple data types. All search strategies are stored, allowing future access and integrated searches. 'User Comments' may be added to any gene page, enhancing available annotation; such comments become immediately searchable via the text search, and are forwarded to curators for incorporation into the reference annotation when appropriate.
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
Martin
M
Aslett
Cristina
C
Aurrecoechea
Matthew
M
Berriman
John
J
Brestelli
Brian P
BP
Brunk
Mark
M
Carrington
Daniel P
DP
Depledge
Steve
S
Fischer
Bindu
B
Gajria
Xin
X
Gao
Malcolm J
MJ
Gardner
Alan
A
Gingle
Greg
G
Grant
Omar S
OS
Harb
Mark
M
Heiges
Christiane
C
Hertz-Fowler
Robin
R
Houston
Frank
F
Innamorato
John
J
Iodice
Jessica C
JC
Kissinger
Eileen
E
Kraemer
Wei
W
Li
Flora J
FJ
Logan
John A
JA
Miller
Siddhartha
S
Mitra
Peter J
PJ
Myler
Vishal
V
Nayak
Cary
C
Pennington
Isabelle
I
Phan
Deborah F
DF
Pinney
Gowthaman
G
Ramasamy
Matthew B
MB
Rogers
David S
DS
Roos
Chris
C
Ross
Dhileep
D
Sivam
Deborah F
DF
Smith
Ganesh
G
Srinivasamoorthy
Christian J
CJ
Stoeckert
Sandhya
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Subramanian
Ryan
R
Thibodeau
Adrian
A
Tivey
Charles
C
Treatman
Giles
G
Velarde
Haiming
H
Wang
D000818:Animals; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D018503:Genome, Protozoan; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D007891:Leishmania / Q000235:genetics*; D017434:Protein Structure, Tertiary; D015800:Protozoan Proteins / Q000235:genetics; D012984:Software; D014345:Trypanosoma / Q000235:genetics*; D014584:User-Computer Interface
D015800:Protozoan Proteins