THE RESISTANCE OF RABBITS TO TUBERCULOSIS AFTER VACCINATION WITH PARTIALLY DEFATTED TUBERCLE BACILLI.
1. A vaccine prepared from partially defatted bovine tubercle bacilli influenced favorably the survival time after inoculation with living virulent bovine tubercle bacilli. 2. Accompanying this increased resistance was a sustained lymphocytosis in the vaccinated animals. 3. The vaccine induced a transitory anemia and leucopenia. 4. A similar preparation of partially defatted human tubercle bacilli possessed the power to sensitize guinea pigs to tuberculo-protein.
Smithburn
K C
KC
Laboratories of The Rockefeller Institute for Medical Research.