Prognostic analysis for carcinoid tumours of the rectum: a single institutional analysis of 106 patients.
OBJECTIVE
Rectal carcinoid is a rare rectal tumour with a good prognosis. The aim of this study was to assess its clinicopathological characteristics and prognostic factors in a single institution.


METHODS
Clinical and pathological information was retrospectively collected in a single institution, and patients' outcomes were determined. Multivariate analyses were performed to find independent prognostic factors attributed to overall survival.


RESULTS
A total of 106 patients with rectal carcinoid were included. In all, 66% of the patients underwent transanal local excision and 34% had transabdominal surgery. The 5-year survival rate was 87%. Muscularis invasion was the only independent prognostic factor for predicting 5-year survival (P = 0.00046). Tumour size was found to be significantly associated with muscular invasion (P = 0.00003). The area under the curve of tumour size in the receiver operating characteristic curve for predicting muscular invasion was 0.92.


CONCLUSIONS
Patients with rectal carcinoid have a good prognosis. Muscular invasion is an independent risk factor of survival.
Department of Colorectal Surgery, Cancer Hospital of Fudan University, Shanghai, China.
M
M
Wang
J
J
Peng
W
W
Yang
W
W
Chen
S
S
Mo
S
S
Cai
D002276:Carcinoid Tumor / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery