Diversity and origin of dengue virus serotypes 1, 2, and 3, Bhutan.
To determine the serotype and genotype of dengue virus (DENV) in Bhutan, we conducted phylogenetic analyses of complete envelope gene sequences. DENV-2 (Cosmopolitan genotype) predominated in 2004, and DENV-3 (genotype III) predominated in 2005-2006; these viruses were imported from India. Primary dengue infections outnumbered secondary infections, suggesting recent emergence.
Dorji
Tandin
T
Ministry of Health, Thimphu, Bhutan.
Yoon
In-Kyu
IK
Holmes
Edward C
EC
Wangchuk
Sonam
S
Tobgay
Tashi
T
Nisalak
Ananda
A
Chinnawirotpisan
Piyawan
P
Sangkachantaranon
Kanittha
K
Gibbons
Robert V
RV
Jarman
Richard G
RG
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000453:epidemiology* / Q000821:virology*; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D010802:Phylogeny; D012703:Serotyping; D055815:Young Adult