G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer: greater selectivity than monomer.
Macrocyclic hexaoxazole (6OTD) dimers were designed as candidates for potent G-quadruplex binders and synthesized.
Iida
Keisuke
K
Department of Biotechnology and Life Science Faculty of Technology, Tokyo University of Agriculture and Technology (TUAT), Koganei, Tokyo 184-8588, Japan.
Tera
Masayuki
M
Hirokawa
Takatsugu
T
Shin-ya
Kazuo
K
Nagasawa
Kazuo
K
D019281:Dimerization; D054856:G-Quadruplexes; D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D016615:Telomere / Q000737:chemistry / Q000378:metabolism
D047028:Macrocyclic Compounds; D010080:Oxazoles