CRISPI: a CRISPR interactive database.
CONCLUSIONS
The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers.


BACKGROUND
CRISPI free access at http://crispi.genouest.org


BACKGROUND
croussea@irisa.fr; jnicolas@irisa.fr
IRISA-INRIA, Campus de Beaulieu, 35042 Rennes cedex, France. croussea@irisa.fr; jnicolas@irisa.fr
Christine
C
Rousseau
Mathieu
M
Gonnet
Marc
M
Le Romancer
Jacques
J
Nicolas
D001105:Archaea / Q000235:genetics; D001419:Bacteria / Q000235:genetics; D030561:Databases, Nucleic Acid; D019143:Evolution, Molecular; D020745:Genome, Archaeal; D016680:Genome, Bacterial; D023281:Genomics / Q000379:methods; D012091:Repetitive Sequences, Nucleic Acid; D012984:Software