THE IMMUNIZING ANTIGEN OF THE PNEUMOCOCCUS : III. THE PURIFICATION OF THE WATER-SOLUBLE ANTIGEN.
Actively immunizing fractions of protein nature have been isolated from broth culture filtrates of Pneumococcus Type I by ultrafiltration, precipitation at a definite hydrion concentration, and the separation of a soluble picrate fraction. The method appears to be suitable for the initial purification of this antigen.
Perlzweig
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Chemical Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.
Keefer
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CS