ANAPHYLACTIC SENSITIZATION WITH CHEMICALLY DEFINITE COMPOUNDS.
Injection of sodium atoxyl-diazoamino-sulfoanthranilate into guinea pigs produces an anaphylactic hypersensitiveness to the corresponding azoprotein (Schultz-Dale test). This leads to the conclusion that the injected sodium atoxyl-diazoamino-sulfoanthranilate first decomposes and then couples in vivo with the body protein to form the corresponding azoprotein and that therefore it is this compound, produced within the organism itself, which sensitizes.
Chemical Laboratory, Federal Polytechnic Institute, and the Dermatological Clinic of the University of Zurich, Zurich, Switzerland.
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Fierz
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Jadassohn
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Stoll