Linking inflammation to natural killer T cell activation.
Immune activation is often associated with inflammation, but inflammation's role in the expansion of antigen-specific immune responses remains unclear. This primer focuses on recent findings that show how specific natural killer T cells are activated by inflammatory messengers, thus illuminating the cellular and molecular links between immunity and inflammation.
Salio
Mariolina
M
Nuffield Department of Clinical Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Cerundolo
Vincenzo
V
D000818:Animals; D017951:Antigen Presentation; D055610:Antigens, CD1d / Q000276:immunology; D015551:Autoimmunity; D006801:Humans; D007249:Inflammation / Q000276:immunology*; D008213:Lymphocyte Activation; D008244:Lysophosphatidylcholines / Q000276:immunology; D055611:Natural Killer T-Cells / Q000276:immunology*
D055610:Antigens, CD1d; D008244:Lysophosphatidylcholines