Geometric analysis of melamine crystal: a problematic molecule inducing renal failure in melamine intoxication.
In 2007, there was emerging toxic nephropathy due to melamine. Renal failure due to melamine crystal is noted in cases of melamine intoxication. In this article, the author studies the melamine crystal by the molecular docking technique and found that the size of crystal is a possible explanation for why the infantile population is more prone to develop renal failure after intoxication.
Wiwanitkit
Viroj
V
Wiwanitkit House, Bangkhae, Bangkok, Thailand. wviroj@yahoo.com
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000503:physiopathology; D000818:Animals; D001669:Biochemical Phenomena; D003460:Crystallization; D006801:Humans; D011041:Poisoning / Q000209:etiology* / Q000503:physiopathology; D013329:Structure-Activity Relationship; D014227:Triazines / Q000737:chemistry* / Q000633:toxicity*
D014227:Triazines; C011907:melamine