Subtyping of emm1 group A Streptococci causing invasive infections in France.
By combining PCR amplification of toxin-encoding genes and sic gene sequencing, we distinguished 24 genotypes among 47 M/emm1 group A streptococci isolated from children and adults in France in 9 cases of infection comprising four clusters and 38 unrelated invasive infection cases used as controls.
Bidet
P
P
Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant, Université Paris VII, UFR Médicale, EA 3105, Assistance Publique-Hôpitaux de Paris, Paris, France.
Lesteven
E
E
Doit
C
C
Liguori
S
S
Mariani-Kurkdjian
P
P
Bonacorsi
S
S
Bingen
E
E
D000293:Adolescent; D000328:Adult; D000942:Antigens, Bacterial / Q000235:genetics*; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015373:Bacterial Typing Techniques; D002352:Carrier Proteins / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005098:Exotoxins / Q000235:genetics / Q000378:metabolism; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D055815:Young Adult
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D005098:Exotoxins; C097739:SIC protein, Streptococcus; C027951:erythrogenic toxin; C014689:streptococcal M protein