Hygiene and urinary tract infections after cystectomy in 452 Swedish survivors of bladder cancer.
OBJECTIVE
To determine whether or not an improved hygiene can lessen the incidence of symptomatic urinary tract infections (UTIs) in patients treated by cystectomy for urinary bladder cancer.


METHODS
We attempted to contact during their follow-up all men and women aged 30-80 years who had undergone cystectomy and urinary diversion at seven Swedish hospitals. During a qualitative phase we identified hygienic measures and included them in a study-specific questionnaire. The patients completed the questionnaire at home. Outcome variables were dichotomized and the results presented as relative risks (RR) with 95% confidence interval.


RESULTS
We received the questionnaire from 452 (92%) of 491 identified patients. The proportion of patients who had a symptomatic UTI in the previous year was 22% for orthotopic neobladder and cutaneous continent reservoir, and 23% for non-continent urostomy diversion. The RR for a UTI was 1.1 (0.5-2.5) for 'never washing hands' before handling with catheters or ostomy material. Patients with diabetes mellitus had a RR of 2.1 (1.4-3.2) for having a symptomatic UTI.


CONCLUSIONS
We could not confirm lack of hygiene measures as a cause of UTI for men and women who had a cystectomy with urinary diversion. Patients with diabetes mellitus have a greater risk of contracting a UTI.
Division of Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden. helena.thulin@ki.se
Helena
H
Thulin
Gunnar
G
Steineck
Ulrika
U
Kreicbergs
Erik
E
Onelöv
Christer
C
Ahlstrand
Malcolm
M
Carringer
Sten
S
Holmäng
Börje
B
Ljungberg
Per-Uno
PU
Malmström
David
D
Robinsson
Hans
H
Wijkström
N Peter
NP
Wiklund
Lars
L
Henningsohn
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015653:Cystectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006920:Hygiene; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D011788:Quality of Life; D017741:Survivors / Q000706:statistics & numerical data*; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014547:Urinary Diversion; D016476:Urinary Reservoirs, Continent; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*