BIOMETRY OF CALCIUM, INORGANIC PHOSPHORUS, CHOLESTEROL, AND LIPOID PHOSPHORUS IN THE BLOOD OF RABBITS : II. REPEATED OBSERVATIONS ON NORMAL ANIMALS.
A series of determinations of inorganic phosphorus, calcium, cholesterol, and lecithin were made on a group of 10 animals living in the laboratory from Oct. 27, 1927, to May 17, 1928. A marked difference in both the trend and absolute values was noted in animals living in the laboratory when compared with the values obtained for animals living out-of-doors. With animals living in the open, the trend of variation for calcium was found to be the same. However, animals living in the laboratory maintained a higher level over the same period of time. The inorganic phosphorus and lecithin both showed a marked decrease and both maintained a lower level than was found in animals just received from the dealer. The cholesterol content of whole blood exhibited a similar trend in both groups of animals. However, it was found that animals living in the laboratory maintained a lower level than animals living out-of-doors. The mean value for calcium was found to be 15.7 +/-0.05, for inorganic phosphorus 4.65 +/-0.05 mg. per 100 cc. of blood serum, and for cholesterol 58.2 +/-0.39 and lecithin 118.4 +/-1.13 mg. per 100 cc. of whole blood. The coefficients of correlation having the highest degree of mathematical significance were obtained from the mean values for individual animals.
Laboratories of The Rockefeller Institute for Medical Research.
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Harnes