Organic-inorganic composites for bone drug delivery.
This review paper attempts to provide an overview in the fabrication and application of organic-inorganic based composites in the field of local drug delivery for bone. The concept of local drug delivery exists for a few decades. However, local drug delivery in bone and specially application of composites for delivery of drugs to bone is an area for potential research interest in the recent time. The advantages attained by an organic-inorganic composite when compared to its individual components include their ability to release drug, adopting to the natural environment and supporting local area until complete bone regeneration, which make them carriers of interest for local drug delivery for bone.
Soundrapandian
Chidambaram
C
Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India.
Sa
Biswanath
B
Datta
Someswar
S
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001673:Biodegradation, Environmental; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000378:metabolism*; D016503:Drug Delivery Systems; D004655:Emulsions; D005612:Freeze Drying; D006133:Growth Substances / Q000008:administration & dosage; D006801:Humans; D044367:Phase Transition; D012995:Solubility; D013678:Technology, Pharmaceutical; D014835:Volatilization
D000900:Anti-Bacterial Agents; D004655:Emulsions; D006133:Growth Substances