Depression and diabetes among low-income Hispanics: design elements of a socioculturally adapted collaborative care model randomized controlled trial.
OBJECTIVE
This article describes design elements of the Multifaceted Depression and Diabetes Program (MDDP) randomized clinical trial. The MDDP trial hypothesizes that a socioculturally adapted collaborative care depression management intervention will reduce depressive symptoms and improve patient adherence to diabetes self-care regimens, glycemic control, and quality-of-life. In addition, baseline data of 387 low-income, 96% Hispanic, enrolled patients with major depression and diabetes are examined to identify study population characteristics consistent with trial design adaptations.


METHODS
The PHQ-9 depression scale was used to identify patients meeting criteria for major depressive disorder (1 cardinal depression symptom + a PHQ-9 score of > or = 10) from two community safety net clinics. Design elements included sociocultural adaptations in recruitment and efforts to reduce attrition and collaborative depression care management.


RESULTS
Of 1,803 diabetes patients screened, 30.2% met criteria for major depressive disorder. Of 387 patients enrolled in the clinical trial, 98% had Type 2 diabetes, and 83% had glycated hemoglobin (HbA1c) levels > or = 7%. Study recruitment rates and baseline data analyses identified socioeconomic and clinical factors that support trial design and intervention adaptations. Depression severity was significantly associated with diabetes complications, medical comorbidity, greater anxiety, dysthymia, financial worries, social stress, and poorer quality-of-life.


CONCLUSIONS
Low-income Hispanic patients with diabetes experience high prevalence of depressive disorder and depression severity is associated with socioeconomic stressors and clinical severity. Improving depression care management among Hispanic patients in public sector clinics should include intervention components that address self-care of diabetes and socioeconomic stressors.
Ell
Kathleen
K
School of Social Work, University of Southern California, Los Angeles, CA 90089-0411, USA. ell@usc.edu
Katon
Wayne
W
Cabassa
Leopoldo J
LJ
Xie
Bin
B
Lee
Pey-Jiuan
PJ
Kapetanovic
Suad
S
Guterman
Jeffry
J
D000328:Adult; D000368:Aged; D002140:California; D003131:Combined Modality Therapy; D003299:Cooperative Behavior; D054521:Cultural Competency; D003866:Depressive Disorder / Q000208:ethnology* / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology* / Q000628:therapy; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D033183:Interdisciplinary Communication; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D020380:Needs Assessment; D010348:Patient Care Team; D010353:Patient Education as Topic; D011203:Poverty / Q000208:ethnology*; D011613:Psychotherapy; D012947:Social Work