Engineered nanoparticle surfaces for improved mass spectrometric analyses.
Engineering of nanoparticle surface functionality provides controlled interactions with biomolecules such as cell membrane lipids, proteins and nucleic acids. Concurrently, this surface chemistry control also opens up new avenues for improving mass spectral analyses. In this Minireview, we highlight some of the emerging work that integrates surface-engineered nanoparticles with mass spectrometry to improve the analysis of a wide variety of chemical and biological systems.
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Zheng-Jiang
ZJ
Zhu
Vincent M
VM
Rotello
Richard W
RW
Vachet
D002616:Chemical Engineering; D013058:Mass Spectrometry / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D013499:Surface Properties