Association between initial and final transient heart rate responses in exercise testing.
BACKGROUND
The rest-exercise-rest transition is accompanied by rapid and slow heart rate (HR) changes modulated by the branches of the autonomic nervous system. Vagal participation seems to be distinct in these different transitions. Additionally, it is methodologically difficult to determine the best moment and how to measure resting HR.


OBJECTIVE
To determine the association between initial (rapid and slow) and final transient HR responses during exercise, considering different forms of measuring resting HR.


METHODS
We retrospectively studied 103 non-athlete adults (76 males) who underwent 4-second exercise test to obtain the rapid transient HR response as measured by the cardiac vagal index (CVI), and completed a maximal cardiopulmonary exercise test in exactly 10 minutes. HR changes were measured in the first few minutes of exercise (DeltaHR) and recovery (dHR).


RESULTS
Modest associations were found between CVI and the three forms of measuring DeltaHR, r between 0.27 and 0.31 (p<0.05), and a more significant association between dHR and CVI, r=0.53 (p<0.05). The means of the three measurements of resting HR were different (p<0.05) and showed only reasonable correlations between them (r between 0.64 and 0.76; p<0.05).


CONCLUSIONS
It is important to standardize the measurement of resting HR for the analysis of transient HR responses; small or moderate association between the results of the different transients suggests that partially distinct autonomic mechanisms are involved and that their measurements may provide different and potentially complementary clinical information.
Mattioli
Gisele Messias
GM
Universidade Gama Filho, Rio de Janeiro, RJ, Brasil.
Araújo
Claudio Gil Soares de
CG
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012146:Rest; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult