THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE : II. THE TOXIC EFFECT OF KILLED BACTERIA IN ADRENALECTOMIZED RATS.
1. The resistance of rats to bacterial intoxication is greatly decreased after double adrenalectomy. 2. This decreased resistance is dependent upon a functional insufficiency of the adrenal cortex. 3. A dose of killed streptococci or staphylococci can be obtained that is invariably fatal to adrenalectomized rats, before hypertrophy of cortical accessories, but never kills control rats.
Scott
W J
WJ
Laboratory of Surgical Research of Harvard Medical School, Boston.