Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli.
The catabolism of phosphonic acids occurs in Escherichia coli by the carbon-phosphorus lyase pathway, which is governed by the 14-cistron phn operon. Here, several compounds are shown to accumulate in strains of E. coli with genetic blocks in various phn cistrons when the strains are fed with phosphonate.
Department of Biology, University of Copenhagen, 5 Ole Maaløes Vej, DK-2200 Copenhagen N, Denmark. hove@mermaid.molbio.ku.dk
Bjarne
B
Hove-Jensen
Tina J
TJ
Rosenkrantz
David L
DL
Zechel
Martin
M
Willemoës
D002855:Chromatography, Thin Layer; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D008190:Lyases / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D009876:Operon / Q000235:genetics / Q000502:physiology*; D063065:Organophosphonates / Q000378:metabolism*; D010761:Phosphorus Radioisotopes / Q000378:metabolism
D029968:Escherichia coli Proteins; D063065:Organophosphonates; D010761:Phosphorus Radioisotopes; D008190:Lyases; C051328:carbon-phosphorus lyase