TriTrypDB: a functional genomic resource for the Trypanosomatidae.
TriTrypDB (http://tritrypdb.org) is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs. TriTrypDB is a collaborative project, utilizing the GUS/WDK computational infrastructure developed by the Eukaryotic Pathogen Bioinformatics Resource Center (EuPathDB.org) to integrate genome annotation and analyses from GeneDB and elsewhere with a wide variety of functional genomics datasets made available by members of the global research community, often pre-publication. Currently, TriTrypDB integrates datasets from Leishmania braziliensis, L. infantum, L. major, L. tarentolae, Trypanosoma brucei and T. cruzi. Users may examine individual genes or chromosomal spans in their genomic context, including syntenic alignments with other kinetoplastid organisms. Data within TriTrypDB can be interrogated utilizing a sophisticated search strategy system that enables a user to construct complex queries combining multiple data types. All search strategies are stored, allowing future access and integrated searches. 'User Comments' may be added to any gene page, enhancing available annotation; such comments become immediately searchable via the text search, and are forwarded to curators for incorporation into the reference annotation when appropriate.
Aslett
Martin
M
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
Aurrecoechea
Cristina
C
Berriman
Matthew
M
Brestelli
John
J
Brunk
Brian P
BP
Carrington
Mark
M
Depledge
Daniel P
DP
Fischer
Steve
S
Gajria
Bindu
B
Gao
Xin
X
Gardner
Malcolm J
MJ
Gingle
Alan
A
Grant
Greg
G
Harb
Omar S
OS
Heiges
Mark
M
Hertz-Fowler
Christiane
C
Houston
Robin
R
Innamorato
Frank
F
Iodice
John
J
Kissinger
Jessica C
JC
Kraemer
Eileen
E
Li
Wei
W
Logan
Flora J
FJ
Miller
John A
JA
Mitra
Siddhartha
S
Myler
Peter J
PJ
Nayak
Vishal
V
Pennington
Cary
C
Phan
Isabelle
I
Pinney
Deborah F
DF
Ramasamy
Gowthaman
G
Rogers
Matthew B
MB
Roos
David S
DS
Ross
Chris
C
Sivam
Dhileep
D
Smith
Deborah F
DF
Srinivasamoorthy
Ganesh
G
Stoeckert
Christian J
CJ
Subramanian
Sandhya
S
Thibodeau
Ryan
R
Tivey
Adrian
A
Treatman
Charles
C
Velarde
Giles
G
Wang
Haiming
H
D000818:Animals; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D018503:Genome, Protozoan; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D007891:Leishmania / Q000235:genetics*; D017434:Protein Structure, Tertiary; D015800:Protozoan Proteins / Q000235:genetics; D012984:Software; D014345:Trypanosoma / Q000235:genetics*; D014584:User-Computer Interface
D015800:Protozoan Proteins