[Bioproduction of pharmaceutical proteins: review and perspectives].
The increase in importance of the biopharmaceutical market generates enormous needs in production of therapeutic molecules. The world capacities of production, mainly therapeutic proteins, impossible to obtain by chemical synthesis, are at present insufficient. Besides the economic aspects in set, play, the question of the technologies used to produce these molecules is important: the tried(felt) technologies (bacteria, yeasts, cells of mammals), used for a long time rather widely remain expensive, or see their limited field of application; the innovative technologies (avian cells, animal and plant transgenic, among others), as for them, again have to show their ability.
Dumas
Joëlle
J
Genopole Campus 1, Evry, France. joelle.dumas@genopole.fr
Robert
Bénédicte
B
D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics*; D001709:Biotechnology / Q000592:standards / Q000639:trends; D002626:Chemistry, Pharmaceutical / Q000639:trends; D006801:Humans; D030821:Plants, Genetically Modified / Q000235:genetics*; D011506:Proteins / Q000235:genetics*; D012106:Research / Q000639:trends; D013678:Technology, Pharmaceutical / Q000639:trends
D011506:Proteins