[In vitro studies of the mechanical load capability of resorbable monofilament suture materials].
In a vast spectrum of wound closures there is an indication for resorbable suture materials. For surgeons detailed knowledge of the physicochemical properties is important in order to find the right suture for each indication. For this purpose, various new monofilament polymers were employed. The objective of the present study was to investigate the effects of hydrolysis and gamma-irradiation on the linear strength. The final analysis of all tested suture materials concluded that gamma-irradiation had no effects on linear strength. However, the analysis showed significant discrepancies between individual polymers with regard to loss of tensile strength associated with hydrolysis. Polydioxanone- and caprolactone-lactid-based resorbable suture materials both displayed adequate tensile strength after a five-week period of hydrolysis. In comparison the triblock-copolymer is subject to rapid degradation. Polydioxanone- and caprolactone-lactid-based resorbable suture materials are indicated for use in tissues which require mechanical support over a longer period. Monosyn is more suitable for short-term wound support.
Bremer
Felicia
F
Klinik für Zahnärztliche Prothetik und Biomedizinische Werkstoffkunde, Medizinische Hochschule Hannover. Bremer.Felicia@mh-hannover.de
Gellrich
Nils-Claudius
NC
Stiesch
Meike
M
D000042:Absorption; D002208:Caproates; D004146:Dioxanes; D005720:Gamma Rays; D006868:Hydrolysis; D007773:Lactates; D007783:Lactones; D008422:Materials Testing; D019563:Mechanics; D011091:Polyesters; D011092:Polyethylene Glycols; D011108:Polymers; D013537:Sutures; D013718:Tensile Strength; D013997:Time Factors
C473020:2,2'-bis(2-oxazoline)-linked poly(epsilon-caprolactone); D002208:Caproates; D004146:Dioxanes; D007773:Lactates; D007783:Lactones; D011091:Polyesters; D011108:Polymers; C432470:polylactic acid-dioxanone-polyethylene glycol block copolymer; D011092:Polyethylene Glycols; C443643:trimethylene carbonate; C121056:caprolactone