Quantitation of respiratory viruses in relation to clinical course in children with acute respiratory tract infections.
Quantitation of respiratory viruses by PCR could potentially aid in clinical interpretation of PCR results. We conducted a study in children admitted with acute respiratory tract infections to study correlations between the clinical course of illness and semiquantitative detection of 14 respiratory viruses. Clinical improvement was associated with reduction of viral quantity after 3 days of hospitalization.
Department of Medical Microbiology, Academical Medical Centre, University of Amsterdam, room L1-245, Meibergdreef 9, 1105 AZ Amsterdam, TheNetherlands. R.R.Jansen@amc.uva.nl
Rogier R
RR
Jansen
Janke
J
Schinkel
Irene
I
Dek
Sylvie M
SM
Koekkoek
Caroline E
CE
Visser
Menno D
MD
de Jong
Richard
R
Molenkamp
Dasja
D
Pajkrt
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009305:Nasopharynx / Q000821:virology*; D016133:Polymerase Chain Reaction / Q000379:methods; D012141:Respiratory Tract Infections / Q000473:pathology* / Q000821:virology*; D012720:Severity of Illness Index; D013223:Statistics as Topic; D019562:Viral Load; D014777:Virus Diseases / Q000473:pathology* / Q000821:virology*; D014780:Viruses / Q000302:isolation & purification*