The value of measurement of macular carotenoid pigment optical densities and distributions in age-related macular degeneration and other retinal disorders.
There is increasing recognition that the optical and antioxidant properties of the xanthophyll carotenoids lutein and zeaxanthin play an important role in maintaining the health and function of the human macula. In this review article, we assess the value of non-invasive quantification of macular pigment levels and distributions to identify individuals potentially at risk for visual disability or catastrophic vision loss from age-related macular degeneration, and we consider the strengths and weaknesses of the diverse measurement methods currently available.
Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA. paul.bernstein@hsc.utah.edu
Paul S
PS
Bernstein
François C
FC
Delori
Stuart
S
Richer
Frederik J M
FJ
van Kuijk
Adam J
AJ
Wenzel
D002338:Carotenoids / Q000378:metabolism*; D006801:Humans; D014975:Lutein / Q000097:blood; D008268:Macular Degeneration / Q000097:blood / Q000378:metabolism*; D010857:Pigment Epithelium of Eye / Q000737:chemistry*; D012164:Retinal Diseases / Q000378:metabolism; D012307:Risk Factors; D024341:Xanthophylls / Q000097:blood; D065146:Zeaxanthins
D024341:Xanthophylls; D065146:Zeaxanthins; D002338:Carotenoids; D014975:Lutein