Preliminary study of human breast tissue using synchrotron radiation combining WAXS and SAXS techniques.
Using synchrotron radiation, we combined simultaneously wide angle X-ray scattering (WAXS) and small angle X-ray scattering (SAXS) techniques to obtain the scattering profiles of normal and neoplastic breast tissues samples at the momentum transfer range 6.28 nm(-1)<or=Q(=4pi x sin(theta/2)/lambda)<or=50.26 nm(-1) and 0.15 nm(-1)<or=Q<or=1.90 nm(-1), respectively. The results obtained show considerable differences between the scattering profiles of these tissues. We verified that the combination of some parameters (ratio between glandular and adipose peak intensity and third-order axial peak intensity) extracted from scattering profiles can be used for identifying breast cancer.
Departamento de Física e Matemática, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
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D001940:Breast / Q000503:physiopathology*; D001943:Breast Neoplasms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D010865:Pilot Projects; D053838:Scattering, Small Angle; D017356:Synchrotrons; D014961:X-Ray Diffraction / Q000379:methods*