Imaging in the evaluation of renovascular disease.
Renovascular disease (RVD) is an important cause of hypertension in children, as it often is amenable to potentially curative treatment. Imaging aimed at finding RVD therefore needs to have high sensitivity so as not to miss important findings. Digital subtraction angiography is the gold standard investigation. Doppler ultrasonography, computed tomography (CT) angiography and magnetic resonance (MR) angiography can all be helpful, but none has, at present, high enough sensitivity to rule out RVD in a child with a suggestion of that diagnosis.
Tullus
Kjell
K
Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK. TulluK@gosh.nhs.uk
Roebuck
Derek J
DJ
McLaren
Clare A
CA
Marks
Stephen D
SD
D015901:Angiography, Digital Subtraction; D002648:Child; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis*; D007674:Kidney Diseases / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler