Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropenia.
Rhizomucor variabilis and Hormographiella aspergillata rarely cause human infections. This report details a fatal case of a 14-year-old female with leukemia posthematopoietic cell transplant and relapse with refractory pancytopenia. The patient first developed an R. variabilis var. regularior palate infection and later developed a cutaneous H. aspergillata infection while on posaconazole and caspofungin therapy.
Abuali
Mayssa M
MM
Pediatric Infectious Diseases, Mount Sinai Medical Center, New York, New York, USA. mayssa.abu-ali@mssm.edu
Posada
Roberto
R
Del Toro
Gustavo
G
Roman
Elizabeth
E
Ramani
Rama
R
Chaturvedi
Sudha
S
Chaturvedi
Vishnu
V
LaBombardi
Vincent J
VJ
D000293:Adolescent; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003302:Coprinus / Q000145:classification / Q000302:isolation & purification; D003881:Dermatomycoses / Q000175:diagnosis / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000628:therapy; D009091:Mucormycosis / Q000175:diagnosis / Q000382:microbiology; D009181:Mycoses / Q000175:diagnosis / Q000382:microbiology; D009503:Neutropenia / Q000150:complications*; D010159:Palate / Q000382:microbiology; D020103:Rhizomucor / Q000145:classification / Q000302:isolation & purification