[Familial clustering, genetic roots and insights into the pathogenesis of autoimmune diseases].
Genome-wide association studies have dramatically increased our knowledge about the genetic contribution to autoimmune diseases. The identified genes are indicators for signal transduction pathways involved in disease pathogenesis and could contribute to potential new therapeutic approaches.
Medizinische Klinik II, Sektion Rheumatologie, Universität Leipzig, 04103 Leipzig.
M
M
Pierer
C
C
Baerwald
U
U
Wagner
D001327:Autoimmune Diseases / Q000175:diagnosis / Q000235:genetics*; D016000:Cluster Analysis; D008040:Genetic Linkage / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005820:Genetic Testing / Q000379:methods*; D006579:Heterozygote; D006801:Humans; D008957:Models, Genetic; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
D005819:Genetic Markers