Role of chelates in magnetic resonance imaging studies.
Imaging studies are tests performed with a variety of techniques that produce pictures of the inside of a patient's body. Magnetic resonance imaging (MRI) is an imaging technique based on the principles of nuclear magnetic resonance. MRI uses a powerful magnetic field, radio waves, and a computer to produce detailed pictures of organs, soft tissues, bone, and virtually all other internal body structures. Chelates have a wide application in such imaging techniques. Chelates in imaging studies are used alone as radioactive agents or conjugated to monoclonal antibodies or to DNA as radioactive agents. Technetium chelates and gadolinium chelates are being widely used as magnetic resonance contrast media.
Department of Pharmaceutical Chemistry, SD College of Pharmacy and Vocational Studies, Muzaffarnagar, India. tripathilaxmi@rediffmial.com
Laxmi
L
Tripathi
Praveen
P
Kumar
Ranjit
R
Singh
D000911:Antibodies, Monoclonal; D002614:Chelating Agents / Q000737:chemistry; D003287:Contrast Media; D004247:DNA; D003952:Diagnostic Imaging / Q000379:methods*; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging; D019275:Radiopharmaceuticals; D013667:Technetium
D000911:Antibodies, Monoclonal; D002614:Chelating Agents; D003287:Contrast Media; D019275:Radiopharmaceuticals; D013667:Technetium; D004247:DNA; D005682:Gadolinium