THE RELATION OF DOSE OF BACTERIA TO GROUP INFECTION.
A study has been made of the peritoneal reaction in mice after injection of different bacteria in graded dose. Organisms were employed to which the animals were fairly resistant. Under these conditions it was found that as the dosage was decreased a more or less critical point was reached below which infection failed to be initiated. The possible clinical bearings of this observation are discussed.
Biological Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.
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Bloomfield
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Felty