Sphenoid sinus development in choanal atresia.
OBJECTIVE
To study the growth and size of the sphenoid sinuses in choanal atresia patients.


METHODS
Case-control single blinded retrospective study.


METHODS
Fifteen non-syndromic patients (ages 0-26 years old) were selected because they had at least one suitable CT scan (nine bilateral and 11 unilateral=total 20 scans). Twenty age-matched CT scans were used as controls. The following linear measurements were obtained: (1) fronto-zygomatic width, (2) zygomatic width, (3) width of the maxillary sinuses, (4) width of the sphenoid sinuses. Statistical analysis was performed with the exact permutation test in the framework of a parametric analysis of a randomized completed block.


RESULTS
The width measurements of the choanal atresia CT scans did not show any statistically significant difference when compared to their control CT scans except for the zygomatic width in the bilateral choanal atresia patients. In the latter, the width was smaller (p=0.03).


CONCLUSIONS
In unilateral and bilateral choanal atresia patients, there is normal growth of the width of the sphenoid sinuses.
Leclerc
Jacques E
JE
Department of Otolaryngology - Head & Neck Surgery, Laval University, Quebec City, Canada. jeleclerc@ccapcable.com
Leclerc
Jean Thomas
JT
D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D002648:Child; D002657:Child Development / Q000502:physiology; D002675:Child, Preschool; D002754:Choanal Atresia / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008443:Maxillary Sinus / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000254:growth & development*; D011336:Probability; D012016:Reference Values; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D013101:Sphenoid Sinus / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000254:growth & development*; D014057:Tomography, X-Ray Computed; D055815:Young Adult