[Link between diabetes and diastolic dysfunction and the diagnostic role of echocardiography].
Diabetes mellitus, a disease that has been reaching epidemic proportions, is an important risk factor to the development of cardiovascular complication. The left ventricular diastolic dysfunction represents the earliest pre-clinical manifestation of diabetic cardiomyopathy, preceding systolic dysfunction and being able to evolve to symptomatic heart failure. In early stages, these changes appear reversible with tight metabolic control, but as pathologic processes become organized, the changes are irreversible and contribute to an excess risk of heart failure among diabetic patients. Doppler echocardiography provides reliable data in the stages of diastolic function, as well as for systolic function. Combination of pulsed tissue Doppler study of mitral annulus with transmitral inflow may be clinically valuable for obtaining information about left ventricular filling pressure and unmasking Doppler inflow pseudonormal pattern, a hinge point for the progression toward advanced heart failure. Subsequently we give an overview about diabetes and its complications, their clinical relevance and the role of echocardiography in detection of diastolic heart failure in diabetes.
Nagy
András
A
Fovárosi Onkormányzat Uzsoki utcai Kórház I. Belgyógyászati-Kardiológiai Osztály, Budapest. nagycsaba@uzsoki.hu
Cserép
Zsuzsanna
Z
D001783:Blood Flow Velocity; D048909:Diabetes Complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D015150:Echocardiography, Doppler; D054144:Heart Failure, Diastolic / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D007333:Insulin Resistance; D008943:Mitral Valve / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000503:physiopathology