Familial Takayasu's arteritis in female siblings.
Takayasu's arteritis (TA) is a rare chronic vasculitis of the aorta and its main branches. Infectious agents or autoimmunity are thought to influence the pathophysiology. Ethnic preponderance in East Asia and usually affects young Asian women suggesting a possible role of genetic factor in the etiology. We present a rare case of familial TA in female siblings with the involvement of the main branches of aortic arch and renal arteries described by three-dimensional computed tomography (3D-CT). This case is rare familial TA in female siblings with CT angiography, which is feasible in diagnosis and informative for the stage of TA.
Department of Neurology, Seoul Medical Center, Seoul, Republic of Korea.
Jae-Hyeok
JH
Heo
Manho
M
Kim
D000328:Adult; D001013:Aorta, Thoracic / Q000473:pathology; D001241:Aspirin / Q000627:therapeutic use; D000077144:Clopidogrel; D005192:Family Health; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012077:Renal Artery / Q000473:pathology; D035781:Siblings; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin