The successful use of intralipid for treatment of local anesthetic-induced central nervous system toxicity: Some considerations for administration of intralipid in an emergency.
Intralipid has been proposed as a treatment option for local anesthetic (LA) toxicity, which does not respond to traditional resuscitation methods. This paper presents a case report of a patient who developed signs of local anesthetic toxicity and was subsequently treated with 20% Intralipid with a positive response. Some background and practical applications regarding this treatment are discussed.
Espinet
Anthony J
AJ
Gold Coast Hospital, Bond University, Southport, Australia. anthony.espinet@hotmail.com
Emmerton
Mark T
MT
D000328:Adult; D000779:Anesthetics, Local / Q000009:adverse effects*; D002493:Central Nervous System Diseases / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy*; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D000779:Anesthetics, Local; D005217:Fat Emulsions, Intravenous