Parenchyma-sparing resections for pancreatic neoplasms.
OBJECTIVE
In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency.


METHODS
A review of the literature and authors experience was undertaken.


RESULTS
Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results.


CONCLUSIONS
Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.
Crippa
Stefano
S
Department of Surgery, Chirurgia Generale B, Policlinico GB Rossi, University of Verona, Piazzale LA Scuro 10, 37134, Verona, Italy.
Boninsegna
Letizia
L
Partelli
Stefano
S
Falconi
Massimo
M
D006801:Humans; D010535:Laparoscopy; D009364:Neoplasm Recurrence, Local; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000601:surgery*; D016896:Treatment Outcome