Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in a newly established Greek hospital.
One hundred and sixty-four Acinetobacter baumannii isolates, collected from patients hospitalized in a newly established hospital in Northern Greece during the 8-year period (2001-2008) of its operation, were tested for the presence of Ambler class A and D carbapenemases and typed by random amplified polymorphic DNA and pulsed-field gel electrophoresis. Isolates were clustered into five distinct clones. The majority of isolates were carrying the bla(OXA-58) gene, while a new clone emerged in 2008.
Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. annap@med.auth.gr
Anna
A
Papa
Vassiliki
V
Koulourida
Efimia
E
Souliou
D000151:Acinetobacter Infections / Q000453:epidemiology; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000235:genetics; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001426:Bacterial Proteins / Q000235:genetics; D015780:Carbapenems / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D019105:Random Amplified Polymorphic DNA Technique; D055815:Young Adult; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases; C534889:beta-lactamase OXA-58, Acinetobacter baumannii; C063912:carbapenemase