Septo-optic dysplasia with bilateral congenital corneal anesthesia.
Septo-optic dysplasia, or de Morsier syndrome, is characterized by optic nerve hypoplasia with an absent septum pellucidum and/or pituitary abnormalities. Congenital corneal anesthesia is a rare disorder that has been associated with many neurological disorders. Here we present a patient with both conditions who was successfully treated with permanent lateral tarsorrhaphy and aggressive lubrication. To our knowledge, congenital corneal anesthesia has not been reported in association with septo-optic dysplasia. The purpose of this report is to make pediatric ophthalmologists aware of a potential association since the diagnosis of congenital corneal anesthesia is often difficult and delayed.
Chow
Clement C
CC
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA.
Kapur
Rashmi
R
Wood
Michael G
MG
Setabutr
Pete
P
Tu
Elmer Y
EY
D003316:Corneal Diseases / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009900:Optic Nerve / Q000002:abnormalities; D000699:Pain Insensitivity, Congenital / Q000150:complications* / Q000473:pathology; D025962:Septo-Optic Dysplasia / Q000150:complications* / Q000473:pathology; D012688:Septum Pellucidum / Q000002:abnormalities