Molecular epidemiology of clade 1 influenza A viruses (H5N1), southern Indochina peninsula, 2004-2007.
To determine the origin of influenza A virus (H5N1) epizootics in Cambodia, we used maximum-likelihood and Bayesian methods to analyze the genetic sequences of subtype H5N1 strains from Cambodia and neighboring areas. Poultry movements, rather than repeated reintroduction of subtype H5N1 viruses by wild birds, appear to explain virus circulation and perpetuation.
Institut Pasteur, Virology Unit, Phnom Penh, Cambodia. pbuchy@pasteur-kh.org
Philippe
P
Buchy
Mathieu
M
Fourment
Sek
S
Mardy
San
S
Sorn
Davun
D
Holl
Sowath
S
Ly
Sirenda
S
Vong
Vincent
V
Enouf
J S Malik
JS
Peiris
Silvie
S
van der Werf
D000818:Animals; D000835:Animals, Wild; D001717:Birds; D002160:Cambodia / Q000453:epidemiology; D004196:Disease Outbreaks; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D017720:Molecular Epidemiology; D013997:Time Factors