Molecular epidemiology of clade 1 influenza A viruses (H5N1), southern Indochina peninsula, 2004-2007.
To determine the origin of influenza A virus (H5N1) epizootics in Cambodia, we used maximum-likelihood and Bayesian methods to analyze the genetic sequences of subtype H5N1 strains from Cambodia and neighboring areas. Poultry movements, rather than repeated reintroduction of subtype H5N1 viruses by wild birds, appear to explain virus circulation and perpetuation.
Buchy
Philippe
P
Institut Pasteur, Virology Unit, Phnom Penh, Cambodia. pbuchy@pasteur-kh.org
Fourment
Mathieu
M
Mardy
Sek
S
Sorn
San
S
Holl
Davun
D
Ly
Sowath
S
Vong
Sirenda
S
Enouf
Vincent
V
Peiris
J S Malik
JS
van der Werf
Silvie
S
D000818:Animals; D000835:Animals, Wild; D001717:Birds; D002160:Cambodia / Q000453:epidemiology; D004196:Disease Outbreaks; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D017720:Molecular Epidemiology; D013997:Time Factors