Stroke diagnosis with lab-on-a-chip.
A magnetic-based sensing platform with increased sensitivity has been developed for integration into lab-on-a-chip systems. The methodology consists of moving the magnetic particles to the most sensitive spot of the sensor. To demonstrate its effectiveness, the protein S100betabeta, a diagnostic marker for stroke, was used as target protein.
IMEC, Leuven, Belgium.
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Parton
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Lagae
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Borghs
D015374:Biosensing Techniques / Q000295:instrumentation*; D001774:Blood Chemical Analysis / Q000295:instrumentation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation* / Q000379:methods; D018189:Immunomagnetic Separation / Q000295:instrumentation*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D009414:Nerve Growth Factors / Q000097:blood*; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood*; D020521:Stroke / Q000097:blood* / Q000175:diagnosis*
D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins