A case of luteinizing thecoma with sclerosing peritonitis: revisiting a link with anti-epileptic drugs.
Luteinizing thecoma with sclerosing peritonitis (LTSP) is a rare ovarian tumor of unclear etiology and pathogenesis. The diagnostic entity was proposed in 1994, but a number of earlier reports described possible cases, and some suggested an association with anti-epileptic drugs (AEDs). In presenting a new case we review the literature of previous cases to evaluate the possibility of such a link. When cases in reproductively immature patients are considered, evidence for an association between LTSP and AEDs is strongly suggested despite the rarity of the condition.
Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. dwnauen@pitt.edu
David W
DW
Nauen
Allison
A
Martin
Aviva
A
Katz
Debra
D
Cohen
Sarangarajan
S
Ranganathan
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D010051:Ovarian Neoplasms / Q000139:chemically induced* / Q000473:pathology; D010538:Peritonitis / Q000139:chemically induced* / Q000473:pathology; D012598:Sclerosis; D013798:Thecoma / Q000139:chemically induced* / Q000473:pathology
D000927:Anticonvulsants