Downsizing to resectability of a large solid and cystic papillary tumor of the pancreas by single-agent chemotherapy.
Solid and cystic pseudopapillary tumor (SCPT) is an uncommon cancer that typically affects young women. Most patients with SCPT have a favorable prognosis provided a complete resection is attained. There are anecdotal reports of the use of neoadjuvant chemotherapy or radiation therapy for patients with unresectable tumors. We report the case of a 14-year-old female with SCPT who was successfully downsized with gemcitabine before definitive surgical resection.
Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA.
Julie
J
Kanter
David B
DB
Wilson
Steven
S
Strasberg
D000293:Adolescent; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology / Q000627:therapeutic use*; D001706:Biopsy / Q000379:methods; D002291:Carcinoma, Papillary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D018292:Cystadenoma, Papillary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy / Q000379:methods*; D010179:Pancreas / Q000187:drug effects* / Q000473:pathology*; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine