Positively selecting peptides: their job does not end in the thymus.
Peptides able to positively select major histocompatibility complex class II-restricted thymocytes have not yet been defined. Two new reports identify and ascribe important extrathymic functions to several positively selecting peptides for CD4+ T cells.
Wucherpfennig
Kai W
KW
Gagnon
Etienne
E
D015496:CD4-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D008213:Lymphocyte Activation; D010455:Peptides / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology
D000949:Histocompatibility Antigens Class II; D010455:Peptides