Science, technology, and innovation: nursing responsibilities in clinical research.
Clinical research is a systematic investigation of human biology, health, or illness involving human beings. It builds on laboratory and animal studies and often involves clinical trials, which are specifically designed to test the safety and efficacy of interventions in humans. Nurses are critical to the conduct of ethical clinical research and face clinical, ethical, and regulatory challenges in research in many diverse roles. Understanding and addressing the ethical challenges that complicate clinical research is integral to upholding the moral commitment that nurses make to patients, including protecting their rights and ensuring their safety as patients and as research participants.
Department of Bioethics, National Institutes of Health Clinical Center, Building 10/1C118, Bethesda, MD 20892, USA. cgrady@nih.gov
Christine
C
Grady
Maureen
M
Edgerly
D000328:Adult; D035843:Biomedical Research / Q000941:ethics* / Q000458:organization & administration; D002986:Clinical Trials as Topic / Q000941:ethics* / Q000379:methods / Q000451:nursing*; D032781:Codes of Ethics; D003219:Confidentiality / Q000941:ethics; D003220:Conflict, Psychological; D005260:Female; D006801:Humans; D007258:Informed Consent / Q000941:ethics; D008297:Male; D024802:Nurse's Role; D009937:Organizational Objectives; D010344:Patient Advocacy / Q000941:ethics*; D012107:Research Design; D012108:Research Personnel / Q000941:ethics / Q000458:organization & administration