Retrospective diagnosis of congenital cytomegalovirus infection at a school for the deaf by using preserved dried umbilical cord.
A retrospective diagnosis of congenital cytomegalovirus infection was made for 3 of 26 students (12%) with either bilateral profound or severe sensorineural hearing loss at a School for the Deaf in Japan by detecting viral DNA with real-time polymerase chain reaction from dried umbilical cords that had been preserved at home.
Tagawa
Masato
M
Department of Pediatrics, Nagasaki University Hospital, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Tanaka
Hideo
H
Moriuchi
Masako
M
Moriuchi
Hiroyuki
H
D000293:Adolescent; D002648:Child; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005312:Fetal Blood / Q000821:virology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D015997:Neonatal Screening; D019986:Persons with Hearing Disabilities; D015995:Prevalence; D012189:Retrospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D013334:Students; D013997:Time Factors
D004279:DNA, Viral