Discovery and early development of squaraine rotaxanes.
The chemical and photophysical properties of a fluorescent squaraine dye are greatly enhanced when it is mechanically encapsulated inside a tetralactam macrocycle. This feature article describes the synthesis, structure, and photophysical performance of first-generation squaraine rotaxanes, and shows how they can be used as fluorescent imaging probes and chemosensors.
Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Jeremiah J
JJ
Gassensmith
Jeffrey M
JM
Baumes
Bradley D
BD
Smith
D000818:Animals; D018360:Crystallography, X-Ray; D003503:Cyclobutanes / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D051379:Mice; D008819:Mice, Nude; D008968:Molecular Conformation; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry*; D043862:Rotaxanes / Q000138:chemical synthesis / Q000737:chemistry*
D003503:Cyclobutanes; D005456:Fluorescent Dyes; D010636:Phenols; D043862:Rotaxanes; C480596:squaraine