Two new triterpenoid isomers from Nerium oleander leaves.
Two new triterpenoid isomers alpha-neriursate (1) and beta-neriursate (2) have been isolated from the fresh, uncrushed leaves of Nerium oleander and their structures elucidated as 3alpha-acetophenoxy-urs-12-en-28-oic acid and 3beta-acetophenoxy-urs-12-en-28-oic acid, respectively. The structure elucidation is based on spectroscopic methods, including 1D ((1)H NMR, (13)C NMR) and 2D ((1)H-(1)H COSY, NOESY, HMQC, HMBC and J-resolved) NMR data and chemical transformation.
HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan. bina@khi.comsats.net.pk
Bina S
BS
Siddiqui
Nasima
N
Khatoon
Sabira
S
Begum
Saima A
SA
Durrani
D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D030007:Nerium / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D010936:Plant Extracts; D014315:Triterpenes