Depression and epilepsy: a review of multiple facets of their close relation.
Depressive disorders are the most frequent comorbidity of PWE. As discussed in this article, the depressive disorder is another expression of a neurologic disorder with psychiatric symptoms. The high comorbidity of both conditions can be explained by the existence of common pathogenic mechanisms whereby one condition facilitates the occurrence of the other. The negative impact of depressive disorders in the life of PWE is significant; hence, a prompt recognition should be followed by a treatment designed to yield complete symptom remission.
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA; Department of Psychiatry, Rush University Medical Center, Armour Academic Center, 600 South Paulina Street, Suite 202 Chicago, IL 60612, USA; Laboratory of Electroencephalography and Video-EEG-Telemetry, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA; Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. Electronic address: akanner@rush.edu.
Andres M
AM
Kanner
D003863:Depression / Q000150:complications* / Q000473:pathology / Q000523:psychology*; D004827:Epilepsy / Q000150:complications* / Q000473:pathology / Q000523:psychology*; D006801:Humans; D011788:Quality of Life