SUNCT syndrome successfully treated with the combination of oxcarbazepine and gabapentin.
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is a syndrome of intermittent, brief, unilateral, severe paroxysms of orbital-temporal pain recurring multiple times per day. The pain modulation is often very difficult. The reported SUNCT patient is the first who responded to a combination treatment of oxcarbazepine and gabapentin.
University Munster, Department of Neurology, Munster, Germany.
Martin
M
Marziniak
Regina
R
Breyer
Stefan
S
Evers
D000368:Aged; D000588:Amines / Q000008:administration & dosage*; D000700:Analgesics / Q000008:administration & dosage*; D000927:Anticonvulsants / Q000008:administration & dosage*; D002220:Carbamazepine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D003509:Cyclohexanecarboxylic Acids / Q000008:administration & dosage*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D000077206:Gabapentin; D006801:Humans; D008297:Male; D009915:Orbit / Q000294:innervation / Q000503:physiopathology; D050798:SUNCT Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D013788:Thalamus / Q000473:pathology / Q000503:physiopathology; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000187:drug effects / Q000503:physiopathology; D014277:Trigeminal Neuralgia / Q000150:complications / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage*
D000588:Amines; D000700:Analgesics; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; C476610:oxcarbamazepine; D002220:Carbamazepine; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin