Two-photon imaging of multicellular tumor spheroids: a novel method for evaluating the efficacy of CDC25 phosphatase inhibitors.
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Robert
R
Warden
John
J
Saunders
Andrew
A
Tsourkas
D052160:Benzothiazoles / Q000494:pharmacology*; D001583:Benzoxazoles / Q000494:pharmacology*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D017785:Photons; D018874:Spheroids, Cellular / Q000187:drug effects* / Q000473:pathology*; D020687:cdc25 Phosphatases / Q000037:antagonists & inhibitors* / Q000378:metabolism
C535248:2-(2,5-difluorophenyl)-6-((3-(methyl(3-((2-methyl-4,7-dioxo-4,7-dihydro-1,3-benzothiazol-5-yl)amino)propyl)amino)propyl)amino)-1,3-benzoxazole-4,7-dione; D052160:Benzothiazoles; D001583:Benzoxazoles; D020687:cdc25 Phosphatases