Cardiac tumor in juvenile onset Behçet's disease: case report and review of the literature.
Behçet's disease is a chronic multisystemic inflammatory disorder characterized by orogenital ulcerations, uveitis, and occasional cardiac involvement. This report describes an atypical presentation of pediatric Behçet's disease with pulmonary emboli and a cardiac mass. A 16-year-old boy with a 2-year history of oral ulcers presented with weight loss, fever, joint pain, and a large tumor adhering to the free wall of the heart's right ventricle. Surgical biopsy demonstrated endomyocarditis with thrombus formation and led to the diagnosis. At the 2-year follow-up evaluation, intracardiac thrombus and pulmonic emboli had not recurred. Symptom control with immunosuppressive therapy was good.
Adams
Elizabeth E
EE
Department of Pediatric Cardiology, Penn State Hershey Children's Hospital, Mailbox HP14, 500 University Drive, Hershey, PA 17033, USA.
Aluquin
Vincent P R
VP
Bingham
C April
CA
Stone
James R
JR
Pauliks
Linda B
LB
D000293:Adolescent; D001528:Behcet Syndrome / Q000150:complications* / Q000473:pathology / Q000628:therapy; D004452:Echocardiography; D004696:Endocarditis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy