Effect of electrochemically deposited nanohydroxyapatite on bone bonding of sandblasted/dual acid-etched titanium implant.
OBJECTIVE
The aim of this study was to evaluate the effect of an electrochemically deposited nanohydroxyapatite (EDHA) coating on the bone bonding of sandblasted and dual acid-etched titanium implants.


METHODS
One hundred EDHA-coated and uncoated sandblasted/dual acid-etched implants (3 mm in diameter, 10 mm long) were inserted into the femoral condyles of 50 rabbits. The osteotomy sites were enlarged to 3 mm in diameter via a sequence of drills. After 2, 4, 6, 8, and 12 weeks of bone healing, removal torque testing was performed to evaluate the interfacial shear strength of each implant type. The removed implants were prepared and observed with an electron microscope equipped with an energy dispersive electron probe x-ray microanalyzer.


RESULTS
The mean removal torque values for the EDHA-coated implants were 39.6 Ncm at 2 weeks and 40.4 Ncm at 4 weeks; corresponding values for the control implants were 21.1 Ncm and 24.1 Ncm. Removal torque values of the EDHA-coated implants were 87% higher than those of control implants after 2 weeks of healing (P = .015). However, the mean removal torque values for both types of implants were similar after 6, 8, or 12 weeks of healing (no significant differences between the implant surfaces; P > .05).


CONCLUSIONS
The EDHA nanocrystal coating had a beneficial effect on interfacial shear strength during the early stages of bone healing.
Department of Implantology, Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Fuming
F
He
Guoli
G
Yang
Xiaoxiang
X
Wang
Shifang
S
Zhao
D000134:Acid Etching, Dental / Q000379:methods*; D000818:Animals; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D045662:Dental Etching / Q000379:methods*; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D017267:Dental Prosthesis Design; D017886:Durapatite / Q000737:chemistry*; D004577:Electron Probe Microanalysis; D004595:Electroplating; D005269:Femur / Q000601:surgery; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry*; D016348:Osseointegration / Q000502:physiology*; D011817:Rabbits; D033081:Shear Strength; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium / Q000737:chemistry*; D019415:Torque; D014945:Wound Healing / Q000502:physiology; D014961:X-Ray Diffraction
D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D017886:Durapatite; D014025:Titanium