[Expressed sequence tags (ESTs) analysis of Angiostrongylus cantonensis].
A total of 1,277 ESTs of Angiostrongylus cantonensis were downloaded from GenBank and analyzed with BlastX. SignalP V3.0 analysis was applied to predict potential putative antigen or allergen relative proteins with N-terminal secreted signal peptides or signal anchors. BlastX analysis showed that there were 614 ESTs scored more than 100, of which 14 were identical with A. cantonensis, 60 ESTs did not match any proteins in the databases. The identified 614 ESTs could be grouped into 10 categories, 80 ESTs expressed 22 antigen or allergen relative proteins, in which 12 had N-terminal secreted signal peptides and 3 had signal anchors.
Xu
Shi-San
SS
School of Life Sciences, Xiamen University, Xiamen.
Ni
Fang
F
Luo
Da-Min
DM
D017185:Angiostrongylus cantonensis / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D020224:Expressed Sequence Tags; D015801:Helminth Proteins / Q000235:genetics*; D021382:Protein Sorting Signals / Q000235:genetics*
D015801:Helminth Proteins; D021382:Protein Sorting Signals