Recent synthetic studies leading to structural revisions of marine natural products.
Because of the highly unique structures of marine natural products, there are many examples of structures that were originally proposed based on spectral analyses but later proven incorrect. In many cases, the total syntheses of the originally proposed structures of marine natural products has confirmed their incorrectness and the subsequent total syntheses of the newly proposed structures proved the revised structures. This review will show such cases appearing after 2005 and demonstrate how the true structures were elucidated.
Usami
Yoshihide
Y
Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. usami@egly.oups.ac.jp
D000818:Animals; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry*; D055808:Drug Discovery / Q000379:methods*; D008386:Marine Biology / Q000379:methods; D009792:Oceans and Seas; D013057:Spectrum Analysis / Q000379:methods*; D013237:Stereoisomerism
D001688:Biological Products