[Sensitivity of Plasmodium vivax to chloroquine in Laza City, Myanmar].
Fourty-eight patients infected by Plasmodium vivax were randomly divided into chloroquine regimen groups A and B. Each case in group A received a total dosage of 1 200 mg(base) over a 3-day period (600 mg on the first day then 300 mg daily). Cases in group B each received total dosage of 1 500 mg (base) in 3 days (750 mg on the first day then 375 mg daily). Body temperature and blood smears were examined on days 0, 1, 2, 3, 7, 14, 21 and 28, respectively. All patients were negative for asexual parasites within 3 days. The cure rate on day 28 was 100%. Results showed that P. vivax is sensitive to chloroquine in Laza, Myanmar, and chloroquine can still be used for the imported vivax malaria cases at the China-Myanmar border.
Liang
Gui-Liang
GL
College of Basic Medicine/Institute of Vectors and Pathogens, Dali University, Dali 671000, China.
Sun
Xiao-Dong
XD
Wang
Jian
J
Zhang
Zai-Xing
ZX
D000293:Adolescent; D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016780:Malaria, Vivax / Q000188:drug therapy* / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D002052:Myanmar; D010966:Plasmodium vivax; D016896:Treatment Outcome; D055815:Young Adult
D000962:Antimalarials; D002738:Chloroquine