Paced mating behavior persists in rats with vaginocervical Lidocaine.
The present study tested whether the topical application of a local anesthetic (Lidocaine) to the vaginocervical region altered the pattern of paced mating behavior displayed by gonadectomized, hormone-primed female rats. Both rats receiving Lidocaine and rats receiving vehicle exhibited the expected lengthening of contact-return latency as the intensity of the mating stimuli increased (mount<intromission<ejaculation). Although rats given Lidocaine versus vehicle received a greater number of intromissions, no other group differences were observed. The present study found no evidence for a change in behavioral responsiveness following the vaginocervical application of Lidocaine.
Department of Psychological and Brain Sciences, Dartmouth College, Hanover NH 03755, United States.
Sarah H
SH
Meerts
Eilish M
EM
Boisvert
Kersti A
KA
Spjut
Ann S
AS
Clark
D000779:Anesthetics, Local / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D005260:Female; D008012:Lidocaine / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051381:Rats; D020318:Rats, Long-Evans; D011930:Reaction Time / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D014621:Vagina / Q000187:drug effects* / Q000294:innervation*
D000779:Anesthetics, Local; D008012:Lidocaine