Activation of NFkB and coagulation in lung injury by hyperoxia and excessive mechanical ventilation: one more reason "low and slow" is the way to go?
Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
Jeffrey R
JR
Jacobson
Konstantin G
KG
Birukov
D055371:Acute Lung Injury / Q000378:metabolism*; D000818:Animals; D004195:Disease Models, Animal; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D018496:Hyperoxia / Q000150:complications* / Q000378:metabolism; D051379:Mice; D016328:NF-kappa B / Q000378:metabolism*; D017395:Plasminogen Activator Inhibitor 1 / Q000378:metabolism; D012121:Respiration, Artificial / Q000009:adverse effects* / Q000379:methods
D016328:NF-kappa B; D017395:Plasminogen Activator Inhibitor 1; C051321:SERPINE1 protein, human