STUDIES ON THE PREVENTION OF CHOLESTEROL ATHEROSCLEROSIS IN RABBITS : II. THE INFLUENCE OF THYROIDECTOMY UPON THE PROTECTIVE ACTION OF POTASSIUM IODIDE.
1. Thyroidectomy in itself does not cause a rise in blood cholesterol or the development of atherosclerosis in young rabbits. 2. Feeding cholesterol produces hypercholesterolemia and atherosclerotic lesions in rabbits regardless of the presence or absence of the thyroid glands. 3. Potassium iodide prevents the usual hypercholesterolemia and atherosclerosis of the aorta in normal rabbits fed cholesterol, but when the thyroids are removed this protective action disappears.
Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York, and the Department of Medicine, American University of Beirut, Beirut, Syria.
K B
KB
Turner
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GB
Khayat