Recovery from spatial neglect and hemiplegia in a child despite a large anterior circulation stroke and Wallerian degeneration.
Prognosis after stroke in children is difficult given the paucity of literature regarding motor and cognitive recovery. Spatial neglect has been described in children after stroke, yet little evidence exists to guide clinicians and parents regarding its resolution. Wallerian degeneration on magnetic resonance imaging (MRI) suggests poor recovery in neonates and adults. We report near complete resolution of spatial neglect in 4 weeks and significant improvement in hemiplegia in a 9-year-old boy with a right anterior cerebral artery and middle cerebral artery infarction, despite Wallerian degeneration apparent on diffusion-weighted imaging. Serial assessment of neglect documenting the rapid course of recovery is the unique feature of this case and may help serve as a guide to pediatricians and neurologists in assessment of young patients and counseling of parents. The lack of published outcome data suggests a need for larger studies about the recovery of spatial neglect and other cognitive symptoms following pediatric stroke.
Department of Neurology, John Hopikns University School of Medicine, Baltimore, MD 21287, USA.
Jonathan T
JT
Kleinman
Philippe
P
Gailloud
Lori C
LC
Jordan
D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D020520:Brain Infarction / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D006801:Humans; D020243:Infarction, Anterior Cerebral Artery / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D020244:Infarction, Middle Cerebral Artery / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D010468:Perceptual Disorders / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D011379:Prognosis; D020127:Recovery of Function / Q000502:physiology; D012720:Severity of Illness Index; D013028:Space Perception / Q000502:physiology; D014796:Visual Perception / Q000502:physiology; D014855:Wallerian Degeneration / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology