Nephrotic syndrome: a watershed in the understanding of membranous nephropathy.
Proof has at last been provided that idiopathic membranous nephropathy is caused by autoantibodies to proteins expressed by podocytes. The discovery that autoantibodies to the M-type secretory phospholipase A2 receptor were present in most individuals affected by the condition opens a new era for the management of membranous nephropathy.
Andrew
A
Rees
Renate
R
Kain
D001323:Autoantibodies / Q000276:immunology*; D015433:Glomerulonephritis, Membranous / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D009404:Nephrotic Syndrome / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology*
D001323:Autoantibodies