First report of a mixed infection due to Acanthamoeba genotype T3 and Vahlkampfia in a cosmetic soft contact lens wearer in Iran.
Acanthamoeba keratitis cases have emerged in the recent years in Iran. In this case, an amoebic keratitis due to a mixed infection with Acanthamoeba and Vahlkampfia species is reported. Corneal scrapes, contact lenses and contact lens cases obtained from the patient were analysed and were positive for cysts of Acanthamoeba and Vahlkampfia genera. Genus-specific PCR was carried out for both genera, confirming the microscopic observations. To our knowledge, this is the first reported case of a possible mixed amoebic infection due to Acanthamoeba and Vahlkampfia and raises awareness within contact lens wearers in Iran.
Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Maryam
M
Niyyati
Jacob
J
Lorenzo-Morales
Sasan
S
Rezaie
Firoozeh
F
Rahimi
Carmen M
CM
Martín-Navarro
Mehdi
M
Mohebali
Amir H
AH
Maghsood
Shohreh
S
Farnia
Basilio
B
Valladares
Mostafa
M
Rezaeian
D000048:Acanthamoeba / Q000145:classification* / Q000235:genetics; D015823:Acanthamoeba Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D000328:Adult; D000562:Amebiasis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001550:Benzamidines / Q000627:therapeutic use; D003263:Contact Lenses, Hydrophilic / Q000469:parasitology*; D003315:Cornea / Q000469:parasitology; D005260:Female; D005838:Genotype; D006801:Humans; D007492:Iran; D008969:Molecular Sequence Data; D016847:Schizopyrenida / Q000145:classification / Q000235:genetics / Q000502:physiology*
D000981:Antiprotozoal Agents; D001550:Benzamidines; C046651:propamidine isethionate