Asymmetric addition of alkenylstannanes to alkylidene Meldrum's acids.
Herein, we describe enantioselective addition of alkenyltin reagents possessing a reactive and sensitive allylic functionality not readily available to other classes of alkenyl metals. This method is enabled by the use of highly electrophilic alkylidene Meldrum's acids as acceptors and a cationic Rh(I)-diene complex as catalyst.
Department of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Stuart J
SJ
Mahoney
Aaron M
AM
Dumas
Eric
E
Fillion