Disseminated histoplasmosis in AIDS: a report of three patients.
Histoplasmosis is a fungal infection caused by Histoplasma capsulatum. Although uncommon, it should be considered among the list of important opportunistic infections in severely immunocompromised patients. Patients living with AIDS are at particular risk of disseminated histoplasmosis. Diagnosis requires a high level of clinical suspicion. The infection is best confirmed by demonstration of the organism in tissue specimens or by culture. Amphotericin B is the most effective drug for severe disseminated histoplasmosis. Response is good but life-long maintenance is required to prevent relapse.
Department of Medicine, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysian, Jalan Tenteram, Cheras, 56000 Kuala Lumpur.
H J
HJ
Tan
I
I
Cheong
W M
WM
Muhaizan
D017088:AIDS-Related Opportunistic Infections; D000328:Adult; D006658:Histoplasma / Q000187:drug effects / Q000472:pathogenicity; D006660:Histoplasmosis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged