Engineered nanoparticle surfaces for improved mass spectrometric analyses.
Engineering of nanoparticle surface functionality provides controlled interactions with biomolecules such as cell membrane lipids, proteins and nucleic acids. Concurrently, this surface chemistry control also opens up new avenues for improving mass spectral analyses. In this Minireview, we highlight some of the emerging work that integrates surface-engineered nanoparticles with mass spectrometry to improve the analysis of a wide variety of chemical and biological systems.
Zhu
Zheng-Jiang
ZJ
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Rotello
Vincent M
VM
Vachet
Richard W
RW
D002616:Chemical Engineering; D013058:Mass Spectrometry / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D013499:Surface Properties