Time-resolved multichannel imaging of fluorescent objects embedded in turbid media.
We present a multichannel detection technique for three-dimensional imaging of objects embedded in turbid media by using time-resolved fluorescence. By using a streak camera, we can obtain the experimental data in a single measurement. The data, analyzed by means of a triangulation algorithm, provide accurate localization of a fluorescent object for path lengths of up to 120 scattering mean free paths. The results demonstrate the feasibility of combining fluorescence spectroscopy with time-resolved optical tomography for localizing and identifying embedded objects.
Wu
J
J
Wang
Y
Y
Perelman
L
L
Itzkan
I
I
Dasari
R R
RR
Feld
M S
MS