Assessment of depth perception using psychophysical thresholds and stereoscopically evoked brain activity.
Dynamic random-dot stereograms (dRDS) elicit brain activity generated exclusively by cortical neurons sensitive to binocular horizontal disparity. We studied 20 adults with stereovision deficiency but otherwise normal vision. Psychophysical thresholds were determined with static RDS and with the three-rod experiment. VEP was recorded from seven occipital channels. Stimuli were presented on a monitor by dRDS as stereoscopic checkerboard patterns that moved in depth with 8 depth reversals per second. Horizontal disparity ranged from 7 to 24.5 min of arc. Stimuli were displayed at the center, or in the left or right half field. We determined electrophysiological thresholds as well as the disparity where largest responses occurred. Subjective and electrophysiological thresholds showed a significant positive correlation. In addition, the right visual field was more sensitive to dRDS stimuli than other locations. Squint angle was related to the disparity thresholds. Our data illustrate correlations between clinical symptoms, perceptual deficiency, and VEP parameters.
Institute of Physiology, Justus-Liebig University, Aulweg 129, 35392, Giessen, Germany. wolfgang.skrandies@physiologie.med.uni-giessen.de
Wolfgang
W
Skrandies
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D003867:Depth Perception / Q000502:physiology*; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D009474:Neurons / Q000502:physiology; D010468:Perceptual Disorders / Q000503:physiopathology; D010775:Photic Stimulation; D011601:Psychophysics; D012684:Sensory Thresholds; D013285:Strabismus / Q000503:physiopathology; D015357:Vision Disparity; D015348:Vision, Binocular / Q000502:physiology; D014794:Visual Fields