Bilateral deepening of upper lid sulcus from topical bimatoprost therapy.
OBJECTIVE
To report a new adverse effect related to treatment with bimatoprost.


METHODS
Case report. A 43-year-old Asian female with bilateral glaucoma was noticed to have bilateral deepening of upper lid sulcus 3 months after beginning treatment with bimatoprost 0.03%.


RESULTS
Bimatoprost was discontinued due to cosmetic reasons, and there was improvement of the lid sulcus deepening bilaterally 4 weeks after stopping the drug.


CONCLUSIONS
Deepening of upper lid sulcus is one of the adverse effects related to treatment with bimatoprost. This effect may be more prominent in Asians who have relatively full upper lid sulcus.
Department of Ophthalmology, Tung Wah Eastern Hospital, Prince of Wales Hospital, Hong Kong, People's Republic of China. jasonyam418@yahoo.com.hk
Jason C S
JC
Yam
Nancy S Y
NS
Yuen
Clement W N
CW
Chan
D000287:Administration, Topical; D000328:Adult; D000577:Amides / Q000009:adverse effects* / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D044466:Asian People; D000069580:Bimatoprost; D003008:Cloprostenol / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005141:Eyelid Diseases / Q000139:chemically induced*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions
D000577:Amides; D000959:Antihypertensive Agents; D009883:Ophthalmic Solutions; D003008:Cloprostenol; D000069580:Bimatoprost