QUANTITATIVE EXPERIMENTS WITH ANTIBODIES TO SPECIFIC PRECIPITATES. II.
1. Antisera have been produced in chickens with specific precipitates from Type II pneumococcus horse and rabbit antisera. 2. Specific precipitates from anti-Types I and II pneumococcus horse sera removed the same amount of antibody from the chicken anti-horse specific precipitate serum. Specific precipitates from horse antisera to diphtheria toxin and to crystalline egg albumin removed about one-half of the antibody. 3. Specific precipitates from anti-egg albumin, antipneumococcus C substance, and anti-Type II pneumococcus rabbit sera removed the same amount of antibody from the chicken anti-rabbit specific precipitate serum. 4. No antibody was removed from the chicken anti-horse specific precipitate serum by rabbit specific precipitates or from the chicken anti-rabbit specific precipitate serum by horse specific precipitates. 5. It is concluded that the antigenic specificities of antibodies from the horse and rabbit are not influenced by their particular antibody functions.
Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York City.
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Treffers
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Heidelberger