The expression levels of the pro-apoptotic XAF-1 gene modulate the cytotoxic response to Nutlin-3 in B chronic lymphocytic leukemia.
Secchiero
P
P
di Iasio
M G
MG
Melloni
E
E
Voltan
R
R
Celeghini
C
C
Tiribelli
M
M
Dal Bo
M
M
Gattei
V
V
Zauli
G
G
D048868:Adaptor Proteins, Signal Transducing; D000328:Adult; D000368:Aged; D051017:Apoptosis Regulatory Proteins; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D047908:Intracellular Signaling Peptides and Proteins; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000235:genetics*; D010879:Piperazines / Q000494:pharmacology*; D013237:Stereoisomerism
D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D007093:Imidazoles; D047908:Intracellular Signaling Peptides and Proteins; D009363:Neoplasm Proteins; D010879:Piperazines; C417551:XAF1 protein, human; C482205:nutlin 3