Primary and secondary immune response to measles vaccine strain.
The rates of primary and secondary cell-mediated immune responses and their correlation with humoral responses were estimated. Cell-mediated reactions were evaluated by the leucocyte migration inhibition test. No significant differences were found in the intensity of primary and secondary cellular responses. The cell-mediated response was not intensified by complete Freund adjuvant, which stimulated the humoral response. The kinetics of changes in cell-mediated reaction was comparable with that observed for other viruses.
Department of Virology, National Institute of Hygiene, Chocimska 24, 00-791 Warszawa, Poland.
W
W
Abramow-Newerly
B
B
Litwińska
J
J
Litwińska
W
W
Sadowski
M
M
Kańtoch
D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D054441:Cell Migration Assays, Leukocyte; D005620:Freund's Adjuvant / Q000008:administration & dosage; D006168:Guinea Pigs; D007117:Immunization, Secondary; D008458:Measles Vaccine / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D008458:Measles Vaccine; D005620:Freund's Adjuvant