Cardiac involvement in dengue virus infections during the 2004/2005 dengue fever season in Sri Lanka.
Sri Lanka experienced a dramatic increase in dengue cases (15,400) in the 2004 - 2005 season. We carried out a prospective study to investigate cardiac involvement in dengue virus infected patients during the 2004 - 2005 season in Peradeniya, Central Province, Sri Lanka. Cardiac involvement was defined as elevated levels of myoglobin, creatine kinase-muscle brain-type, N-terminal pro-brain natriuretic peptide, heart-type fatty acid-binding protein and troponin T. Twenty-five percent of dengue virus infected patients had one or more of the above tests with abnormal results.
Medical Department - Infectious Diseases and Tropical Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany. wichmann@bni-hamburg.de
Dominic
D
Wichmann
Senanayake
S
Kularatne
Stephan
S
Ehrhardt
Sriyal
S
Wijesinghe
Norbert W
NW
Brattig
Walter
W
Abel
Gerd D
GD
Burchard
D000293:Adolescent; D000328:Adult; D000368:Aged; D052279:Creatine Kinase, MB Form / Q000097:blood; D055316:Cystatin C / Q000097:blood; D003715:Dengue / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood; D005260:Female; D006331:Heart Diseases / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D015995:Prevalence; D011446:Prospective Studies; D013188:Sri Lanka / Q000453:epidemiology; D019210:Troponin I / Q000097:blood; D055815:Young Adult
C525030:CST3 protein, human; D055316:Cystatin C; C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins; D010446:Peptide Fragments; D019210:Troponin I; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D052279:Creatine Kinase, MB Form