Vulvar pyoderma gangrenosum in a child.
We present a case of a 10-year-old girl with a diagnosis of vulvar pyoderma gangrenosum. Intravenous methylprednisolone was started and on tapering the steroid regimen, the lesion showed significant enlargement and purulent discharge without any remission of fever and inflammatory activity, so she was treated with oral cyclosporin A in combination with low-dose steroid. A response to treatment was achieved after 2 weeks and clinical and laboratory follow-up at 12 months did not show any disease relapse or inflammation.
Department of Dermatology, Catholic University, A. Gemelli Hospital, Rome, Italy.
Simon
S
Garcovich
Antonio
A
Gatto
Pietro
P
Ferrara
Antonio
A
Garcovich
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001706:Biopsy; D002648:Child; D016572:Cyclosporine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008775:Methylprednisolone / Q000008:administration & dosage*; D017511:Pyoderma Gangrenosum / Q000188:drug therapy* / Q000473:pathology; D014847:Vulvitis / Q000188:drug therapy* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D008775:Methylprednisolone