Sp-sp(3) C-C bond formation via Fe(OTf)(3)/TfOH cocatalyzed coupling reaction of terminal alkynes with benzylic alcohols.
An Fe(OTf)(3)/TfOH cocatalyzed sp-sp(3) C-C bond formation through the coupling of benzylic alcohols with terminal alkynes in the absence of base has been developed. H(2)O is the sole by-product.
Xiang
Shi-Kai
SK
State Key Laboratory of Natural and Biomimetic Drugs, Peking University, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China.
Zhang
Li-He
LH
Jiao
Ning
N
D000480:Alkynes / Q000737:chemistry*; D001592:Benzyl Alcohols / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D058085:Iron Compounds / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*
D000480:Alkynes; D001592:Benzyl Alcohols; D058085:Iron Compounds; D008698:Mesylates; D002244:Carbon