Dynamic kinetic resolution in the asymmetric synthesis of atropisomeric biaryl[4] and [5]helicene quinones.
Total control of axial and helical chirality elements of a (2-biphenyl)-substituted tetrahydro[5]helicene quinone and the configurationally stable dihydro[4]helicene analogue was achieved in a dynamic kinetic resolution process of an axially chiral racemic diene promoted by an enantiopure sulfinyl benzoquinone.
Departamento de Química Orgánica (C-I), Universidad Autónoma de Madrid, 28049-Madrid, Spain.
Alfonso
A
Latorre
Antonio
A
Urbano
M Carmen
MC
Carreño
D007536:Isomerism; D007700:Kinetics; D008958:Models, Molecular; D011809:Quinones / Q000737:chemistry*
D011809:Quinones