Mechanisms of COPI vesicle formation.
Coat Protein I (COPI) is one of the most intensely investigated coat complexes. Numerous studies have contributed to a general understanding of how coat proteins act to initiate intracellular vesicular transport. This review highlights key recent findings that have shaped our current understanding of how COPI vesicles are formed.
Hsu
Victor W
VW
Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA 02115, USA. vhsu@rics.bwh.harvard.edu
Yang
Jia-Shu
JS
D020823:ADP-Ribosylation Factor 1 / Q000378:metabolism; D000818:Animals; D020755:Coat Protein Complex I / Q000378:metabolism*; D022162:Cytoplasmic Vesicles / Q000378:metabolism*; D020690:GTPase-Activating Proteins / Q000378:metabolism; D020662:Guanine Nucleotide Exchange Factors / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism
D020755:Coat Protein Complex I; D020690:GTPase-Activating Proteins; D020662:Guanine Nucleotide Exchange Factors; D020823:ADP-Ribosylation Factor 1