THE INFLUENCE OF PLASMA PROTEIN ON THE CHLORIDE CONTENT OF THE CEREBROSPINAL FLUID.
1. When the plasma protein of dogs is lowered by plasmapheresis, the concentration of chloride and sodium in the plasma and the cerebrospinal fluid tends to become the same, a diminishing of the usual disparity which exists in the presence of a normal plasma protein. 2. This is in accord with the theory that the cerebrospinal fluid is a dialysate, with the choroid plexus acting as a simple dialyzing membrane.
Laboratory for Surgical Research and the Department of Biochemistry, Harvard Medical School, Boston.
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Coombs
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Thompson