[Clinical observation of Flos magnoliae volatile oil nano-liposome nasal drops in treating pediatric allergic rhinitis].
OBJECTIVE
To observe the clinical efficacy of Flos Magnoliae volatile oil nano-liposome nasal drops (FMO) in treating pediatric allergic rhinitis (PAR).


METHODS
Adopting parallel controlled method, the 191 patients with PAR were randomized into two groups. The observation group was treated with FMO, and the control group with Cetirizine. The clinical efficacy, main symptoms, signs, syndromes scores of Chinese medicine, and peripheral eosinophil (EOS) count were observed after 3-week treatment.


RESULTS
In the observation group, the total effective rate was 94.84%, which was higher than that in the control group (78.72%); the effective rate on alleviating main symptoms (sneezing, nasal obstruction), signs (nasal mucosa edema, pallor) and the EOS count were significantly lowered, all were better than those in the control group (P <0.05).


CONCLUSIONS
FMO has some positive effects on PAR, it might be realized by lowering the peripheral EOS.
Department of Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University, Shanghai. minwu@eastday.com
Min
M
Wu
Jing-Yan
JY
Zhang
Xin
X
Zhang
D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal; D004804:Eosinophils; D005260:Female; D006801:Humans; D008081:Liposomes / Q000627:therapeutic use; D008297:Male; D009822:Oils, Volatile / Q000627:therapeutic use*; D008517:Phytotherapy; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D008081:Liposomes; D009822:Oils, Volatile