The UK scheme for mandatory continuous monitoring of early transplant outcome in all kidney transplant centers.
Mandatory continuous monitoring of early transplant outcome with centralized oversight was introduced in 2004 for all 23 UK adult kidney transplant units. Risk-adjusted cumulative sum charts are used to assess 30-day graft and patient survival against past performance for each center, and change in transplant center performance is assessed by tabular cumulative sum charts. The monitoring scheme has performed as predicted from simulations used to establish outcome thresholds and has been validated by comparison with 1- and 5-year outcome data for all UK transplant centers. The value and limitations of the scheme are discussed along with changes that may improve its utility as a tool for self-assessment and central oversight.
Statistics and Clinical Audit, NHS Blood and Transplant, Bristol, United Kingdom. dave.collett@nhsbt.nhs.uk
Dave
D
Collett
Nokuthaba
N
Sibanda
Sue
S
Pioli
J Andrew
JA
Bradley
Chris
C
Rudge
D000293:Adolescent; D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality / Q000502:physiology*; D037141:Mandatory Programs / Q000331:legislation & jurisprudence*; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods / Q000592:standards*; D011237:Predictive Value of Tests; D019057:Quality-Adjusted Life Years; D013223:Statistics as Topic; D016019:Survival Analysis; D017741:Survivors; D013997:Time Factors; D016896:Treatment Outcome; D006113:United Kingdom; D055815:Young Adult