Thymoma developing 30 years after mantle radiation for Hodgkin's lymphoma.
Treatment-related malignancies are widely reported in the medical literature. They are usually chemotherapy-related leukemias or radiation-induced solid tumors. Here we present a case of a 47-year-old woman treated with mantle radiation for Hodgkin's lymphoma who later developed a thymoma in the setting of a venous thrombosis. A review of the literature including surveillance recommendations for secondary malignancies will be discussed.
Goldstein
Mark G
MG
University of Connecticut, Department of Hematology/Oncology, Farmington, USA.
Siegel
Robert
R
D005260:Female; D006689:Hodgkin Disease / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D013945:Thymoma / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013953:Thymus Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013997:Time Factors