[Yeast susceptibility isolated from blood cultures of patients at the National Cardiology Institute Ignacio Chávez].
BACKGROUND
With the increasing prevalence of bloodstream infections caused by Candida sp. is necessary to establish the susceptibility of resistant strains in various geographical regions.


OBJECTIVE
To determine the in vitro susceptibility to fluconazole, itraconazole, voriconazole and amphotericin B in yeasts isolated from blood through E test method.


METHODS
In the period from 1992 to 2007, a total 112 strains of Candida species were isolated from blood of patients at the National Institute of Cardiology Ignacio Chavez. Susceptibility of these strains was performed to know the level of resistance to Itraconazole, Fluconazole, Voriconazole and Amphotericine B by E test method.


RESULTS
C. albicans was the most common species (60.2%), followed by C. tropicalis (9.8%). A five percent of resistance to itraconazole, 1.8% to fluconazole; and 0.9% to amphotericine B and voriconazole were found. C. glabrata was the most resistant species to the four antifungal agents.


CONCLUSIONS
The yeasts resistance to the four antifungal agents is still lower in our patients.
Hernández-Dueñas
Ana María del Rocío
AM
Departamento de Infectología y Microbiología Clínica, Instituto Nacional de Cardiología Ignacio Chávez. anishernandez@hotmail.com
Vázquez-Larios
Ma del Rosario
Mdel R
Soto-Nieto
Gabriel Israel
GI
Rivera-Martínez
Eduardo
E
D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology*; D001769:Blood / Q000382:microbiology; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
D000935:Antifungal Agents