[Marjolin's ulcer: malignant transformation of a crural ulcer due to posttraumatic chronic osteomyelitis].
We report on the case of an 81-year-old female patient who developed a squamous cell carcinoma in a long-lasting therapy-resistant crural ulcer of the lower leg due to posttraumatic chronic osteomyelitis. Eventually the lower leg had to be amputated because of massive destruction of soft tissue and the tibia bone. Based on the desolate wound conditions plastic reconstruction by a pivoted muscle flap and surgical covering with mesh graft plastic was also necessary.The amputation stump had completely healed 6 months after surgery and the patient is fitted with an artificial limb ensuring independent mobility even outside the home. Up to the present there is no evidence of any tumor recurrence or progression.
Klinik für Unfall-, Wiederherstellungs- und Handchirurgie, Städtisches Klinikum Dresden-Friedrichstadt, 01067, Dresden, Deutschland. bula-ph@khdf.de
P
P
Bula
J
J
Bula-Sternberg
U
U
Wollina
G
G
Haroske
F
F
Bonnaire
D000369:Aged, 80 and over; D000671:Amputation, Surgical; D001186:Artificial Limbs; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002908:Chronic Disease; D018450:Disease Progression; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007869:Leg Injuries / Q000473:pathology* / Q000601:surgery*; D007871:Leg Ulcer / Q000473:pathology* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D009367:Neoplasm Staging; D010019:Osteomyelitis / Q000473:pathology* / Q000601:surgery*; D011552:Pseudomonas Infections / Q000473:pathology* / Q000601:surgery*; D011550:Pseudomonas aeruginosa; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology* / Q000601:surgery; D013977:Tibia / Q000473:pathology / Q000601:surgery*; D014950:Wounds, Penetrating / Q000473:pathology* / Q000601:surgery*