Focal liver lesions hyperintense on T1-weighted magnetic resonance images.
This article reviews focal liver lesions hyperintense on T1-weighted magnetic resonance (MR) images and describes the underlying etiologies associated with their T1 signal intensity. Although focal liver lesions are commonly detected because of their iso- or hypointensity on T1-weighted images, lesions (benign or malignant) may present with T1 hyperintensity when they contain T1 shortening elements--such as fat, hemorrhage, copper, melanin, and highly concentrated proteins. Our discussion includes the description of state-of-the-art T1-weighted MR sequences and the imaging features of lesions on pre- and postcontrast MR images that are characteristic for lesion composition and useful for making accurate diagnosis.
Furlan
Alessandro
A
University of Pittsburgh Medical Center, Department of Radiology, 3362 Fifth Avenue, Pittsburgh, PA 15213, USA. furlana@upmc.edu
Marin
Daniele
D
Bae
Kyongtae T
KT
Lagalla
Roberto
R
Agnello
Francesco
F
Bazzocchi
Massimo
M
Brancatelli
Giuseppe
G
D003287:Contrast Media; D003937:Diagnosis, Differential; D006801:Humans; D021621:Imaging, Three-Dimensional; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*
D003287:Contrast Media