New terpenoids from the soft corals Sinularia capillosa and Nephthea chabroli.
Two new terpenoids, capillosanol (1) and chabranol (2), possessing unprecedented terpenoid skeletons, were isolated from the soft corals Sinularia capillosa and Nephthea chabroli, respectively. The structures of 1 and 2 were elucidated through extensive spectroscopic analyses. The cytotoxicities of these compounds were tested in vitro.
Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Shi-Yie
SY
Cheng
Ki-Jhih
KJ
Huang
Shang-Kwei
SK
Wang
Zhi-Horng
ZH
Wen
Chi-Hsin
CH
Hsu
Chang-Feng
CF
Dai
Chang-Yih
CY
Duh
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000970:Antineoplastic Agents; D013729:Terpenes; C545601:capillosanol; C545600:chabranol