Conservative management of low-grade endometrial stromal sarcoma followed by pregnancy and severe recurrence.
BACKGROUND
Since low-grade endometrial stromal sarcoma (LGESS) has the most favourable prognosis in comparison to other sarcomas, fertility-sparing surgery in young women has been reported in rare cases. However, such tumours almost always show positive sex steroid receptors and their evolution in the hormonal milieu of pregnancy remains unpredictable.


METHODS
We report the case of a 34-year-old woman treated conservatively for LGESS who conceived rapidly after hysteroscopic resection of the tumour. In the post partum period, pelvic pain motivated a laparoscopic exploration which revealed severe peritoneal recurrence.


CONCLUSIONS
This case report highlights the possible dramatic evolution of LGESS after pregnancy and suggests that definitive surgery should not be postponed but performed as soon as the diagnosis of ESS has been made.
Koskas
Martin
M
Department of Obstetrics and Gynecology, Hospital Bichat-Claude Bernard, 46 Rue Henri Huchard, 75018 Paris, France. martin.koskas@wanadoo.fr
Morice
Philippe
P
Yazbeck
Chadi
C
Duvillard
Pierre
P
Walker
Francine
F
Madelenat
Patrick
P
D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005298:Fertility; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*; D018203:Sarcoma, Endometrial Stromal / Q000473:pathology / Q000601:surgery*