Direct one-pot reductive amination of aldehydes with nitroarenes in a domino fashion: catalysis by gum-acacia-stabilized palladium nanoparticles.
This note describes the direct reductive amination of carbonyl compounds with nitroarenes using gum acacia-palladium nanoparticles, employing molecular hydrogen as the reductant. This methodology is found to be applicable to both aliphatic and aromatic aldehydes and a wide range of nitroarenes. The operational simplicity and the mild reaction conditions add to the value of this method as a practical alternative to the reductive amination of carbonyl compounds.
Indian Institute of Chemical Technology, Council of Scientific and Industrial Research, Hyderabad-500007, India. sreedharb@iict.res.in
B
B
Sreedhar
P Surendra
PS
Reddy
D Keerthi
DK
Devi
D000045:Acacia / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D053768:Metal Nanoparticles / Q000737:chemistry*; D009578:Nitrobenzenes / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013499:Surface Properties
D000447:Aldehydes; D000588:Amines; D009578:Nitrobenzenes; D010165:Palladium