Regioselective copper-catalyzed chlorination and bromination of arenes with O(2) as the oxidant.
Electron-rich aromatic C-H bonds undergo regioselective chlorination and bromination in the presence of CuX(2), LiX (X = Cl, Br) and molecular oxygen. Preliminary mechanistic insights suggest that the bromination and chlorination reactions proceed by different pathways.
Yang
Lujuan
L
State Key Laboratory of Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.
Lu
Zhan
Z
Stahl
Shannon S
SS