LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin.
Regan M
RM
Memmott
Phillip A
PA
Dennis
D000091162:AMP-Activated Protein Kinase Kinases; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D008687:Metformin / Q000494:pharmacology / Q000627:therapeutic use*; D020360:Neoadjuvant Therapy; D011494:Protein Kinases / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D058570:TOR Serine-Threonine Kinases
D008687:Metformin; D011494:Protein Kinases; C546842:MTOR protein, human; D017346:Protein Serine-Threonine Kinases; C109790:STK11 protein, human; D058570:TOR Serine-Threonine Kinases; D000091162:AMP-Activated Protein Kinase Kinases