Subtyping of emm1 group A Streptococci causing invasive infections in France.
By combining PCR amplification of toxin-encoding genes and sic gene sequencing, we distinguished 24 genotypes among 47 M/emm1 group A streptococci isolated from children and adults in France in 9 cases of infection comprising four clusters and 38 unrelated invasive infection cases used as controls.
Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant, Université Paris VII, UFR Médicale, EA 3105, Assistance Publique-Hôpitaux de Paris, Paris, France.
P
P
Bidet
E
E
Lesteven
C
C
Doit
S
S
Liguori
P
P
Mariani-Kurkdjian
S
S
Bonacorsi
E
E
Bingen
D000293:Adolescent; D000328:Adult; D000942:Antigens, Bacterial / Q000235:genetics*; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015373:Bacterial Typing Techniques; D002352:Carrier Proteins / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005098:Exotoxins / Q000235:genetics / Q000378:metabolism; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D055815:Young Adult
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D005098:Exotoxins; C097739:SIC protein, Streptococcus; C027951:erythrogenic toxin; C014689:streptococcal M protein