[A study on relationship between distortion product otoacoustic emissions and therapeutic effects in tinnitus].
OBJECTIVE
To find mechanism of tinnitus and explore effective treatment for tinnitus.


METHODS
The 133 tinnitus patients were assigned into two groups by relationship between Distortion product otoacoustic emissions and frequencies of tinnitus: relationship group (73 cases) and non-relationship group (60 cases). All 133 cases were treated with drug, such as injection of Lipo PGE1, Vitamin B1 and Vitamin B12. After 14 days of treatment the efficacy of the medicines in two groups was observed.


RESULTS
The effective rate of two groups mentioned above were 75.3% and 36.7% respectively (P < 0.01). Furthermore, effective rate was correlative to the course of the tinnitus.


CONCLUSIONS
Drug therapy can be a choice for patients who have relationship between DPOAEs and frequencies of tinnitus, especially for acute tinnitus. Personalized treatment should be provided.
Zhang
Jing
J
Department of Otorhinolaryngology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Zhou
Huifang
H
Xu
Yi
Y
Zhang
Geng
G
D000328:Adult; D001301:Audiometry, Pure-Tone; D005260:Female; D006801:Humans; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous; D014012:Tinnitus / Q000188:drug therapy* / Q000503:physiopathology*; D016896:Treatment Outcome