Lewis acid catalyzed inverse-electron-demand Diels-Alder reaction of tropones.
Lewis acid catalyzed inverse-electron-demand Diels-Alder reaction of tropone derivatives was developed. Up to 97% ee was obtained for the chiral dinucleus BINOL-aluminum complex catalyzed reaction between tropones and ketene diethyl acetal to give bicyclo[3.2.2] ring structures, which opens up a unique way of making chiral seven-membered rings.
Li
Pingfan
P
The University of Chicago, Department of Chemistry, 5735 S Ellis Ave, Chicago, Illinois 60637, USA.
Yamamoto
Hisashi
H