Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a significant regression in the uterine and leiomyoma volumes.
Levonorgestrel- (LNG) releasing intrauterine device (IUD) insertion revealed significant reduction in visual bleeding scores and spotting with an increase in amenorrhea and uterine pulsatility index scores. LNG-IUD can be considered as a simple and effective alternative to surgical treatment in the management of leiomyoma-dependent menorrhagia of reproductive-age women.
Murat Naki
Mehmet
M
Obstetrics and Gynecology Department, Dr Lutfi Kirdar Kartal Research and Training Hospital, Kartal, Istanbul, Turkey. mmuratnaki@yahoo.com
Tekcan
Cevahir
C
Ozcan
Nahit
N
Cebi
Meliha
M
D000328:Adult; D000367:Age Factors; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007436:Intrauterine Devices, Medicated; D007889:Leiomyoma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D016912:Levonorgestrel / Q000008:administration & dosage*; D008595:Menorrhagia / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D014599:Uterus / Q000187:drug effects* / Q000473:pathology; D055815:Young Adult
D003692:Delayed-Action Preparations; D016912:Levonorgestrel