title: Survey on warfarin pharmacogenetic testing among anticoagulation providers.
abstract: OBJECTIVE
  Our study aimed to assess anticoagulation providers' perception and knowledge of warfarin pharmacogenetic testing, and to identify barriers to using it in their clinical practice.
  
  
  METHODS
  An online survey that included 5 perception and 5 knowledge questions about the testing was conducted on anticoagulation providers in North America. Participants were also asked to rank the three most significant barriers to using it.
  
  
  RESULTS
  The survey response rate was 22%. Over 40% of 448 providers participating in the study were undecided about the testing's potential clinical benefits. On average, providers correctly answered 2 out of 5 knowledge questions. Self confidence in interpreting test results significantly predicted the providers' accuracy of the interpretation. The top three barriers were inadequate literature evidence, testing's impracticality and unproven applicability.
  
  
  CONCLUSIONS
  Most of the providers did not respond to the survey. Our study suggests inadequate literature evidence influences providers' perception and their use of the testing. In addition, provider education on warfarin pharmacogenetics may be necessary for testing's widespread use.
authors.affiliation: Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA 94143-0622, USA.
authors.forename: Maha
authors.initials: M
authors.lastname: Kadafour
authors.forename: Roshanak
authors.initials: R
authors.lastname: Haugh
authors.forename: Monica
authors.initials: M
authors.lastname: Posin
authors.forename: Steven R
authors.initials: SR
authors.lastname: Kayser
authors.forename: Jaekyu
authors.initials: J
authors.lastname: Shin
mesh_terms: D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000494:pharmacology*; D005260:Female; D006801:Humans; D019359:Knowledge; D008297:Male; D008875:Middle Aged; D010597:Pharmacogenetics; D010818:Practice Patterns, Physicians'; D014859:Warfarin / Q000494:pharmacology*
chemical_list: D000925:Anticoagulants; D014859:Warfarin