Effect of peptides of the insulin superfamily on glucose-6-phosphate dehydrogenase activity in skeletal muscles of river lamprey (Lampetra fluviatilis) during prespawning starvation.
Glucose-6-phosphate dehydrogenase activity in skeletal muscles of the lamprey (Lampetra fluviatilis) decreased during prespawning starvation (September-May). The observed changes were particularly pronounced in January. Insulin, insulin-like growth factor 1, and relaxin produce an in vitro stimulatory effect on the enzyme. Insulin was most potent in this respect. Inactivation of the enzyme was accompanied by a decrease in its sensitivity to the stimulatory effect of insulin and insulin-like growth factor 1.
Chistyakova
O V
OV
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia. chiosana@yandex.ru
Kuznetsova
L A
LA
D000818:Animals; D001947:Breeding; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D007328:Insulin / Q000737:chemistry / Q000494:pharmacology*; D007798:Lampreys / Q000502:physiology*; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000201:enzymology; D010446:Peptide Fragments / Q000494:pharmacology*; D013217:Starvation
D007328:Insulin; D010446:Peptide Fragments; D005954:Glucosephosphate Dehydrogenase