title: Probabilistic finite element analysis of the uncemented hip replacement--effect of femur characteristics and implant design geometry.
abstract: In the present study, a probabilistic finite element tool was assessed using an uncemented total hip replacement model. Fully bonded and frictional interfaces were investigated for combinations of three proximal femurs and two implant designs, the Proxima short stem and the IPS hip stem prostheses. The Monte Carlo method was used with two performance indicators: the percentage of bone volume that exceeded specified strain limits and the maximum nodal micromotion. The six degrees of freedom of bone-implant relative position, magnitude of the hip contact force (L), and spatial direction of L were the random variables. The distal portion of the proximal femurs was completely constrained and some of the main muscle forces acting in the hip were applied. The coefficients of the linear approximation between the random variables and the output were used as the sensitivity values. In all cases, bone-implant position related parameters were the most sensitive parameters. The results varied depending on the femur, the implant design and the interface conditions. Values of maximum nodal micromotion agreed with results from previous studies, confirming the robustness of the implemented computational tool. It was demonstrated that results from a single model study should not be generalised to the entire population of femurs and that bone variability is an important factor that should be investigated in such analyses.
authors.affiliation: Bioengineering Research Group, School of Engineering Sciences, University of Southampton, United Kingdom. cdg@soton.ac.uk
authors.forename: Carolina
authors.initials: C
authors.lastname: Dopico-González
authors.forename: Andrew M
authors.initials: AM
authors.lastname: New
authors.forename: Martin
authors.initials: M
authors.lastname: Browne
mesh_terms: D002484:Cementation; D003198:Computer Simulation; D017076:Computer-Aided Design; D019544:Equipment Failure Analysis; D005269:Femur / Q000503:physiopathology* / Q000601:surgery*; D020342:Finite Element Analysis; D006622:Hip Prosthesis; D006801:Humans; D008954:Models, Biological; D015233:Models, Statistical; D011474:Prosthesis Design; D025321:Surgery, Computer-Assisted / Q000379:methods