title: Rapid acquisition of in vivo biological images by use of optical coherence tomography.
abstract: The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the highspeed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.
authors.forename: G J
authors.initials: GJ
authors.lastname: Tearney
authors.forename: B E
authors.initials: BE
authors.lastname: Bouma
authors.forename: S A
authors.initials: SA
authors.lastname: Boppart
authors.forename: B
authors.initials: B
authors.lastname: Golubovic
authors.forename: E A
authors.initials: EA
authors.lastname: Swanson
authors.forename: J G
authors.initials: JG
authors.lastname: Fujimoto