title: Near-infrared image-guided laser ablation of dental decay.
abstract: Image-guided laser ablation systems are now feasible for dentistry with the recent development of nondestructive high-contrast imaging modalities such as near-IR (NIR) imaging and optical coherence tomography (OCT) that are capable of discriminating between sound and demineralized dental enamel at the early stages of development. Our objective is to demonstrate that images of demineralized tooth surfaces have sufficient contrast to be used to guide a CO(2) laser for the selective removal of natural and artificial caries lesions. NIR imaging and polarization-sensitive optical coherence tomography (PS-OCT) operating at 1310-nm are used to acquire images of natural lesions on extracted human teeth and highly patterned artificial lesions produced on bovine enamel. NIR and PS-OCT images are analyzed and converted to binary maps designating the areas on the samples to be removed by a CO(2) laser to selectively remove the lesions. Postablation NIR and PS-OCT images confirmed preferential removal of demineralized areas with minimal damage to sound enamel areas. These promising results suggest that NIR and PS-OCT imaging systems can be integrated with a CO(2) laser ablation system for the selective removal of dental caries.
authors.affiliation: University of California, San Francisco, San Francisco School of Dentistry, Department of Preventive and Restorative Dental Sciences, 707 Parnassus Avenue, San Francisco, California 94143-0758, USA.
authors.forename: You-Chen
authors.initials: YC
authors.lastname: Tao
authors.forename: Daniel
authors.initials: D
authors.lastname: Fried
mesh_terms: D000818:Animals; D002417:Cattle; D003731:Dental Caries / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D066298:In Vitro Techniques; D053685:Laser Therapy / Q000379:methods*; D008964:Molar, Third / Q000473:pathology / Q000601:surgery; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*