Autophagy can contribute to cell death when combining targeted therapy.
Amaravadi
Ravi
R
Abramson Cancer Center, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Ravi.amaravadi@uphs.upenn.edu
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D001343:Autophagy / Q000187:drug effects*; D016923:Cell Death / Q000187:drug effects*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D045325:HCT116 Cells; D006801:Humans; D007211:Indoles; D000077341:Lapatinib; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000037:antagonists & inhibitors; D011758:Pyrroles / Q000008:administration & dosage; D011799:Quinazolines / Q000008:administration & dosage
D007211:Indoles; D019253:Proto-Oncogene Proteins c-bcl-2; D011758:Pyrroles; D011799:Quinazolines; D000077341:Lapatinib; C520962:obatoclax