title: [The efficiency of ultraviolet autologous blood irradiation used in the complex therapy of infiltrative pulmonary tuberculosis in children and adolescents].
abstract: The purpose of the investigation was to study the clinical efficiency of ultraviolet autoblood irradiation (UVABI) used in the complex therapy of children and adolescents with infiltrative pulmonary tuberculosis. A controlled randomized study of the results of treatment in two groups of patients who had or had not received UVABI during the standard complex therapy was carried out by the experiment-control principle. The groups were randomized (first - second). In 91.9% of the children and adolescents with infiltrative tuberculosis, the process was accompanied by impaired immune defense with bacterial isolation in 68.0 to 54.1% of cases; every two patients had drug-resistant Mycobacterium tuberculosis. The use of UVABI in the complex therapy of patients with tuberculosis was ascertained to promote a rapid, two-fold more frequent bacterial isolation cessation resulting in a epidemic danger reduction in the patients, to have a positive impact on the formation of immune defense, mainly of a phagocytic link, in children and adolescents, to exert a detoxifying effect, to favor a better tolerability of antituberculous drugs, to cause positive X-ray changes, and to improve the quality of life. The clinical and laboratory effectiveness and safety of UVABI allow recommendation that the latter be introduced into a treatment protocol for children and adolescents with infiltrative pulmonary tuberculosis.
authors.forename: A A
authors.initials: AA
authors.lastname: Shurygin
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use; D001769:Blood / Q000528:radiation effects*; D001804:Blood Transfusion, Autologous / Q000379:methods*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000628:therapy*; D014467:Ultraviolet Therapy / Q000379:methods*
chemical_list: D000995:Antitubercular Agents