Etiopathogenesis of Behcet's disease.
Bechet's disease (BD) is an inflammatory, multi systemic disease with spontaneous remissions and relapses similar to various autoimmune diseases. BD leads to organ damage, including the eyes, skin, joints, etc., which produces various clinical manifestations. The central histopathologic characteristic is systemic vasculitis with perivascular inflammatory infiltrates. The etiopathogenesis is unknown, although immunological abnormalities, possibly induced by susceptible microbiological pathogens, have been postulated.
Mendoza-Pinto
Claudia
C
Systemic Autoimmune Diseases Research Unit, HGR #36, Instituto Mexicano del Seguro Social, Puebla, Mexico.
García-Carrasco
Mario
M
Jiménez-Hernández
Mario
M
Jiménez Hernández
Cesar
C
Riebeling-Navarro
Carlos
C
Nava Zavala
Arnulfo
A
Vera Recabarren
Mauricio
M
Espinosa
Gerard
G
Jara Quezada
Javier
J
Cervera
Ricard
R
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004890:Erythema; D020022:Genetic Predisposition to Disease; D015235:HLA-B Antigens / Q000235:genetics; D059949:HLA-B51 Antigen; D006801:Humans; D008877:Middle East; D007703:Peptidyl-Dipeptidase A / Q000235:genetics; D011110:Polymorphism, Genetic; D011516:Prothrombin / Q000235:genetics; D056647:Systemic Vasculitis; D013927:Thrombosis; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics; D014456:Ulcer
D000305:Adrenal Cortex Hormones; D015235:HLA-B Antigens; D059949:HLA-B51 Antigen; D014409:Tumor Necrosis Factor-alpha; D011516:Prothrombin; C488034:ACE protein, human; D007703:Peptidyl-Dipeptidase A