The yeast Golgi apparatus: insights and mysteries.
The Golgi apparatus is known to modify and sort newly synthesized secretory proteins. However, fundamental mysteries remain about the structure, operation, and dynamics of this organelle. Important insights have emerged from studying the Golgi in yeasts. For example, yeasts have provided direct evidence for Golgi cisternal maturation, a mechanism that is likely to be broadly conserved. Here, we highlight features of the yeast Golgi as well as challenges that lie ahead.
Papanikou
Effrosyni
E
The University of Chicago, Molecular Genetics and Cell Biology, 920 East 58th St., Chicago, IL 60637, USA.
Glick
Benjamin S
BS
D022181:COP-Coated Vesicles / Q000378:metabolism; D049109:Cell Proliferation; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000378:metabolism