High-resolution optical coherence tomography correlates in ischemic radiation retinopathy.
OBJECTIVE
To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT).


METHODS
We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were done using information both at the fovea and 2.5 mm temporal to the fovea.


RESULTS
The layers that were reduced in thickness included the inner plexiform layer (47 microm vs. 74 microm), the inner nuclear layer (17 microm vs. 48 microm), and the outer plexiform layer (25 microm vs. 45 microm), whereas the layers with comparable thickness included the nerve fiber layer (24 microm vs. 25 microm), the outer nuclear layer (42 microm vs. 43 microm), the outer segment-inner segment junction (52 microm vs. 54 microm), and the retinal pigment epithelium (RPE) choriocapillaris layer (30 microm vs. 28 microm).


CONCLUSIONS
This report suggests that the radiation-induced damage was confined to the inner layers of the retina. However, secondary outer retinal layer changes may also occur, as suggested by functional derangements.
Raman
Rajiv
R
Shri Bhagwan Mahavir Vitreoretinal Services, Tamil Nadu, India. rajivpgraman@gmail.com
Pal
Swakshyar Saumya
SS
Krishnan
Tandava
T
Laxmi
Gella
G
Radke
Nishant
N
Sharma
Tarun
T
D000328:Adult; D005134:Eye Neoplasms / Q000532:radiotherapy*; D005451:Fluorescein Angiography; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000532:radiotherapy*; D008297:Male; D011832:Radiation Injuries / Q000209:etiology / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects; D012160:Retina / Q000473:pathology* / Q000528:radiation effects; D012164:Retinal Diseases / Q000209:etiology / Q000473:pathology*; D041623:Tomography, Optical Coherence