title: Early bone formation around immediately restored implants with and without occlusal contact: a human histologic and histomorphometric evaluation. Case report.
abstract: Human biopsy of immediately loaded implants is the most definitive means to determine the occurrence of osseointegration. This case report discusses the histologic and histomorphometric analysis of the bone-titanium interface in immediately restored implants with and without occlusal contact, retrieved after a healing period of 5 weeks. The two implants had been inserted in the posterior mandible; both were freestanding. One implant had been put into functional loading (in occlusal contact) with a fixed provisional prosthesis on the day of implant surgery (implant A), whereas the other implant was restored without occlusal contact (implant B). Both implants were retrieved with a 5-mm trephine after 5 weeks. Before retrieval, both implants appeared to be clinically osseointegrated, and no mobility was present. Both implants were surrounded by newly formed bone lamellae. In both implants about 0.5 to 1 mm of pre-existing and newly formed bone was found coronal to the implant shoulder, with no resorption of the pre-existing coronal bone. The bone-implant contact percentage in implant A was 51.2% +/- 4.5%, whereas in implant B it was 55.1% +/- 2.3%. Within the limitations of this study, the histologic findings indicated that no differences were found in the histologic response around immediately restored implants with and without occlusal contact.
authors.affiliation: Dental School, University of Chieti-Pescara, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Degidi
authors.forename: Adriano
authors.initials: A
authors.lastname: Piattelli
authors.forename: Jamil A
authors.initials: JA
authors.lastname: Shibli
authors.forename: Vittoria
authors.initials: V
authors.lastname: Perrotti
authors.forename: Giovanna
authors.initials: G
authors.lastname: Iezzi
mesh_terms: D001706:Biopsy; D001732:Bite Force; D015519:Bone Density / Q000502:physiology; D001853:Bone Marrow / Q000098:blood supply / Q000473:pathology; D001857:Bone Matrix / Q000473:pathology; D002196:Capillaries / Q000473:pathology; D000044:Dental Abutments; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D003766:Dental Occlusion; D017267:Dental Prosthesis Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation / Q000601:surgery; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D010006:Osteoblasts / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
chemical_list: D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium