[Parkinsonism due to the medication].
Parkinsonism is an extrapyramidal disorder characterised by tremor, muscle rigidity, bradykinesia and postural instability. The most common cause of parkinsonism is idiopathic Parkinson disease. Another common cause is drug-induced parkinsonism. Various drugs can cause parkinsonian symptoms. Many patients exhibiting these side-effects are mistakenly treated with dopaminergic medication. We present two patients with drug-induced parkinsonism induced by sodium valproate and cinnarizine, respectively. The symptoms disappeared after they stopped taking this medication.
Louter
Maartje
M
St Antonius Ziekenhuis, Afd. Neurologie, locatie Nieuwegein, The Netherlands.
Tromp
Selma C
SC
D000368:Aged; D000369:Aged, 80 and over; D002936:Cinnarizine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000175:diagnosis; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D002936:Cinnarizine; D014635:Valproic Acid