title: Surgical management of hepatic metastases of colorectal origin.
abstract: Colorectal cancer is the most frequent digestive cancer. Prognosis is greatly depending on the TNM stage at the time of diagnosis. Fifty percent of all patients shall develop, synchronously or metachronously, liver metastases. Different means such as chemotherapy, targeted therapies, radiofrequency ablation, portal vein embolization and two-stage hepatectomy may be used to make these metastases eventually resectable and to increase overall survival. This is a short review of these different methods used to increase resectability but also on the integration of these parameters in a larger approach of colorectal liver metastasis surgery especially insisting on multidisciplinary discussion.
authors.affiliation: Service de chirurgie abdominale, sénologique, endocrine et de transplantation, CHU de Liège, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: Gilson
authors.forename: C
authors.initials: C
authors.lastname: Honoré
authors.forename: O
authors.initials: O
authors.lastname: Detry
authors.forename: A
authors.initials: A
authors.lastname: De Roover
authors.forename: C
authors.initials: C
authors.lastname: Coimbra
authors.forename: L
authors.initials: L
authors.lastname: Kohnen
authors.forename: M
authors.initials: M
authors.lastname: Polus
authors.forename: P
authors.initials: P
authors.lastname: Piront
authors.forename: D
authors.initials: D
authors.lastname: Van Daele
authors.forename: P
authors.initials: P
authors.lastname: Honoré
authors.forename: M
authors.initials: M
authors.lastname: Meurisse
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*