title: [Designing a tool to describe drug interactions and adverse events for learning and clinical routine].
abstract: Pharmacists play an important role in prescription analysis. They are involved in therapeutic drug monitoring, particularly for drugs with a narrow therapeutic index, prevention and management of drug interactions, and may be called in to identify side effects and adverse events related to drug therapy. For the polymedicated patient, the medical file, the list of prescribed drugs and the history of their administration may be insufficient to adequately assign the responsibility of a given adverse effect to one or more drugs. Graphical representations can sometimes be useful to describe and clarify a sequence of events. In addition, as part of their academic course, students have many occasions to hear about "side effects" and "drug interactions". However, in the academic setting, there are few opportunities to observe the evolution and the consequences of these events. In the course of their hospital training, these students are required to perform patient follow-up for pharmacotherapeutic or educational purposes and to comment case reports to physicians. The aim of this paper is to present a tool facilitating the graphic display of drug interaction consequences and side effects. This tool can be a useful aid for causality assessment. It structures the students' training course and helps them better understand the commentaries pharmacists provide for physicians. Further development of this tool should contribute to the prevention of adverse drug events.
authors.affiliation: Service de pharmacie, hôpital de la Croix-Rousse, hospices civils de Lyon, 3, Quai-Célestins, 69002 Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Auzéric
authors.forename: J
authors.initials: J
authors.lastname: Bellemère
authors.forename: O
authors.initials: O
authors.lastname: Conort
authors.forename: R
authors.initials: R
authors.lastname: Roubille
authors.forename: B
authors.initials: B
authors.lastname: Allenet
authors.forename: P
authors.initials: P
authors.lastname: Bedouch
authors.forename: F-X
authors.initials: FX
authors.lastname: Rose
authors.forename: M
authors.initials: M
authors.lastname: Juste
authors.forename: B
authors.initials: B
authors.lastname: Charpiat
mesh_terms: D000935:Antifungal Agents / Q000009:adverse effects; D001296:Audiovisual Aids; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D004513:Education, Pharmacy, Continuing / Q000379:methods*; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007958:Leukocyte Count; D010595:Pharmacists; D011743:Pyrimidines / Q000009:adverse effects; D012984:Software; D013339:Students, Pharmacy; D016559:Tacrolimus / Q000009:adverse effects; D014230:Triazoles / Q000009:adverse effects; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole; D016559:Tacrolimus