title: [Adrenal vein thrombosis during pregnancy].
abstract: Pregnancy represents an inner transitional prothrombotic state; that is why other coagulation abnormalities may be revealed during this time. Factor V Leiden mutation is the most frequent inherited thrombophilia in the general population. We report the case of a patient by whom this mutation has been revealed during pregnancy by an adrenal vein thrombosis. Through this case, we will review the physiopathology of resistance to activated protein C and its consequences.
authors.affiliation: Service de gynécologie obstétrique, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Schmitt
authors.forename: M-P
authors.initials: MP
authors.lastname: Debord
authors.forename: C
authors.initials: C
authors.lastname: Grange
authors.forename: A
authors.initials: A
authors.lastname: Ben Cheikh
authors.forename: J-P
authors.initials: JP
authors.lastname: Krauth
authors.forename: O
authors.initials: O
authors.lastname: Dupuis
authors.forename: F
authors.initials: F
authors.lastname: Golfier
authors.forename: D
authors.initials: D
authors.lastname: Raudrant
mesh_terms: D020016:Activated Protein C Resistance / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D000311:Adrenal Glands / Q000098:blood supply*; D005165:Factor V / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D017354:Point Mutation; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D020246:Venous Thrombosis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D055815:Young Adult
chemical_list: C095381:factor V Leiden; D005165:Factor V