title: Mid- to long-term results of irradiated allograft in acetabular reconstruction: a follow-up report.
abstract: Between 1990 and 2000, 123 hips in 110 patients were reconstructed for aseptic loosening using impaction bone grafting with frozen, irradiated, morsellised femoral heads and cemented acetabular components. This series was reported previously at a mean follow-up of five years. We have extended this follow-up and now describe the outcome of 86 hips in 74 patients at a mean of ten years. There have been 19 revisions, comprising nine for infection, seven for aseptic loosening and three for dislocation. In surviving acetabular reconstructions, union of the graft had occurred in 64 of 67 hips (95.5%). Survival analysis for all indications at ten years was 83.3% (95% confidence interval (CI) 68 to 89) and 71.3% (95% CI 58 to 84) at 15 years. Acetabular reconstruction using irradiated allograft and a cemented acetabular component is an effective method of reconstruction, providing results in the medium- to long-term comparable with those of reported series where non-irradiated freshly-frozen bone was used.
authors.affiliation: St Helens and Knowsley, Teaching Hospitals NHS Trust, Warrington Road, Prescot, Merseyside L35 5DR, UK. nick.emms@sthk.nhs.uk
authors.forename: N W
authors.initials: NW
authors.lastname: Emms
authors.forename: S C
authors.initials: SC
authors.lastname: Buckley
authors.forename: I
authors.initials: I
authors.lastname: Stockley
authors.forename: A J
authors.initials: AJ
authors.lastname: Hamer
authors.forename: R M
authors.initials: RM
authors.lastname: Kerry
mesh_terms: D000077:Acetabulum / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005270:Femur Head / Q000528:radiation effects* / Q000637:transplantation; D005500:Follow-Up Studies; D006085:Graft Survival; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation / Q000379:methods; D016019:Survival Analysis; D016896:Treatment Outcome