Evaluation of anterior-segment inflammation and retinal thickness change following cataract surgery.
OBJECTIVE
To investigate the physiological retinal response to uneventful cataract surgery using conventional time-domain (TD-OCT) and current spectral-domain optical coherence tomography (SD-OCT) in combination with an assessment of the anterior chamber inflammatory reaction by laser flare/cell meter (LCFM).


METHODS
Thirty-four patients scheduled for cataract surgery were included in this prospective pilot study. Retinal parameters were examined according to a standardized examination procedure using TD-OCT (Stratus; Carl Zeiss Meditec, Dublin, California, USA) and SD-OCT (Cirrus; Carl Zeiss Meditec) devices. The inflammatory reaction of the anterior chamber was measured by LFCM (Kowa FC-1000, Kowa Co. Ltd, Tokyo, Japan). Examinations were carried out preoperatively and at day 2, week 1 and week 4 postoperatively.


RESULTS
A slight decrease of central retinal thickness values was identified at day 2 postoperatively followed by an increase of these parameters at week 4. LFCM showed peak values in all patients at day 2 postoperatively with a constant decrease at the following visits. No visible pathological retinal changes were seen after surgery.


CONCLUSIONS
A biphasic retinal response after surgery could be shown with SD-OCT and TD-OCT technology. By using the advantages of rasterscanning mode, SD-OCT technology is superior to TD-OCT imaging in the investigation of the physiological retinal response to cataract surgery.
Stock
Geraldine
G
Department of Ophthalmology, Medical University Vienna, Austria.
Ahlers
Christian
C
Dunavoelgyi
Roman
R
Kahraman
Guenal
G
Schauersberger
Joerg
J
Schmidt-Erfurth
Ursula
U
Amon
Michael
M
D000368:Aged; D000369:Aged, 80 and over; D000869:Anterior Eye Segment / Q000473:pathology*; D019923:Capsulorhexis; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D010865:Pilot Projects; D011183:Postoperative Complications; D011446:Prospective Studies; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014606:Uveitis, Anterior / Q000175:diagnosis*