title: Allergic reactions to human insulin: a review of current knowledge and treatment options.
abstract: Although the incidence of insulin allergy decreased after the introduction of recombinant human insulin preparations, it is still a major problem which may be life-threatening in some cases. In this article, we attempted to review current knowledge concerning allergic reactions to human insulin and discuss the available treatment options of insulin allergy.
authors.affiliation: Division of Endocrinology of Metabolism, Department of Internal Medicine, Dokuz Eylul University Medical School, Inciralti, 35340 Izmir, Turkey. baris.akinci@deu.edu.tr
authors.forename: Baris
authors.initials: B
authors.lastname: Akinci
authors.forename: Serkan
authors.initials: S
authors.lastname: Yener
authors.forename: Firat
authors.initials: F
authors.lastname: Bayraktar
authors.forename: Sena
authors.initials: S
authors.lastname: Yesil
mesh_terms: D048909:Diabetes Complications / Q000276:immunology / Q000628:therapy; D004342:Drug Hypersensitivity / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D055104:Infusions, Subcutaneous; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives / Q000627:therapeutic use; D007330:Insulin Antibodies / Q000097:blood / Q000276:immunology*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D007330:Insulin Antibodies