Clinical features and survival outcomes in patients with multiple myeloma: analysis of web-based data from the Korean Myeloma Registry.
OBJECTIVE
The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system.


METHODS
We retrospectively analyzed registered data from 3,209 patients since 1999.


RESULTS
The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20-54.06 months). Patients < or =40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT.


CONCLUSIONS
We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.
Kim
Seok Jin
SJ
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim
Kihyun
K
Kim
Byung Soo
BS
Jo
Deog-Yeon
DY
Kang
Hye Jin
HJ
Kim
Jin Seok
JS
Mun
Yeung-Chul
YC
Kim
Chul Soo
CS
Sohn
Sang Kyun
SK
Eom
Hyeon-Seok
HS
Kwak
Jae-Yong
JY
Shim
Hyeok
H
Yoon
Hwi-Joong
HJ
Jin
Jong-Youl
JY
Min
Chang-Ki
CK
Shin
Hyunchoon
H
Won
Jong-Ho
JH
Lee
Je-Jung
JJ
Kwon
Jung Hye
JH
Joo
Young-Don
YD
Do
Young Rok
YR
Kim
Sung-Hyun
SH
Oh
Sukjoong
S
Suh
Cheolwon
C
Lee
Junglim
J
Yoon
Sung-Soo
SS
Kim
Min Kyoung
MK
Bang
Soo-Mee
SM
Ryoo
Hun-Mo
HM
Kim
Bong-Seog
BS
Kim
Hawk
H
Kim
Hyo Jung
HJ
Kim
Yang Soo
YS
Park
Chong Won
CW
Lee
Gyeong-Won
GW
Shin
Ho Jin
HJ
Park
Seong Kyu
SK
Park
Joon Seong
JS
Kim
Ho Young
HY
Lee
Dong Soon
DS
Lee
Jae Hoon
JH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D020407:Internet; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis / Q000235:genetics / Q000401:mortality* / Q000628:therapy; D011379:Prognosis; D012042:Registries / Q000706:statistics & numerical data; D056910:Republic of Korea / Q000453:epidemiology; D033581:Stem Cell Transplantation; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D055815:Young Adult