title: [Erlotinib and nonsmall cell lung cancer with brain metastases: a case study with a complete and prolonged response over 17 months].
abstract: The prognosis of stage IV nonsmall cell lung cancer, in particular with brain metastases, is extremely poor. The impact of targeted therapy, in particular erlotinib, on patient survival has still not been determined. The authors report the case of a patient diagnosed with nonsmall cell lung cancer with bone and brain metastases. The patient presented a complete cerebral response for 17 months with erlotinib prescribed as a third line therapy.
authors.affiliation: Service de Pneumologie, HIA de Percy, 101, Avenue Henri-Barbusse, BP 406, 92141, Clamart Cedex, France. alexamairovitz@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Mairovitz
authors.forename: E
authors.initials: E
authors.lastname: Staub
authors.forename: H
authors.initials: H
authors.lastname: Le Floch
authors.forename: F
authors.initials: F
authors.lastname: Rivière
authors.forename: A
authors.initials: A
authors.lastname: Bonnichon
authors.forename: J
authors.initials: J
authors.lastname: Margery
authors.forename: F
authors.initials: F
authors.lastname: Vaylet
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary; D018450:Disease Progression; D018572:Disease-Free Survival; D000069347:Erlotinib Hydrochloride; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000532:radiotherapy; D008875:Middle Aged; D011379:Prognosis; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011799:Quinazolines / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D000069347:Erlotinib Hydrochloride