Pulse EPR spectroscopy reveals the coordination sphere of copper(II) ions in the 1-16 amyloid-beta peptide: a key role of the first two N-terminus residues.
Dorlet
Pierre
P
CNRS, Laboratoire du Stress Oxydant et Détoxication, URA 2096, 91191 Gif-sur-Yvette, France. pierre.dorlet@cea.fr
Gambarelli
Serge
S
Faller
Peter
P
Hureau
Christelle
C
D000544:Alzheimer Disease / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000737:chemistry*; D000818:Animals; D003300:Copper / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D006801:Humans; D007477:Ions / Q000737:chemistry*; D015394:Molecular Structure; D017382:Reactive Oxygen Species / Q000737:chemistry
D016229:Amyloid beta-Peptides; D007477:Ions; D017382:Reactive Oxygen Species; D003300:Copper