title: Intracameral recombinant tissue plasminogen activator for refractory glaucoma secondary to a fungal corneal abscess.
abstract: We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery.
authors.affiliation: Wills Eye Institute, 840 Walnut Street, Philadelphia, USA.
authors.forename: L Jay
authors.initials: LJ
authors.lastname: Katz
authors.forename: Oana
authors.initials: O
authors.lastname: Stirbu
authors.forename: Garth
authors.initials: G
authors.lastname: Willis
authors.forename: Parul
authors.initials: P
authors.lastname: Ichhpujani