Primary amine-metal Lewis acid bifunctional catalysts: the application to asymmetric direct aldol reactions.
The first example of metal Lewis acid-primary amine bifunctional cooperative catalyst derived from primary amino acids was developed, and it was found to catalyze aldol reactions of cyclic ketones highly efficiently with very good to excellent stereoselectivities.
Xu
Zhenghu
Z
Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA.
Daka
Philias
P
Wang
Hong
H