Comprehensive noninvasive arterial vascular evaluation.
Noninvasive evaluation of the health of the vasculature is an increasingly important approach to identifying individuals at risk for cardiovascular morbid events. Vascular health assessment involves functional and structural examination of the large and small arteries. Endothelial dysfunction, which alters small artery function, is a key contributor to progressive structural vascular changes. Ultrasonography of conduit arteries and aortic pulse-wave velocity provide information limited to structural changes in large arteries. Comprehensive assessment of the large and small arteries is best carried out by pulse-contour analysis. This can provide insight into functional and structural abnormalities in the small as well as the large arteries, and may be useful in monitoring response to therapy.
Cohn
Jay N
JN
Cardiovascular Division, Mayo Mail Code 508, Minneapolis, MN 55455, USA. cohnx001@umn.edu
Duprez
Daniel A
DA
Finkelstein
Stanley M
SM
D001161:Arteriosclerosis / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D001783:Blood Flow Velocity; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D003971:Diastole; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000473:pathology / Q000503:physiopathology; D009569:Nitric Oxide; D018384:Oxidative Stress; D011674:Pulse; D012307:Risk Factors; D013599:Systole; D014463:Ultrasonography
D009569:Nitric Oxide