title: Penumbra, the basis of neuroimaging in acute stroke treatment: current evidence.
abstract: In modern medicine brain imaging is an essential prerequisite not only to acute stroke triage but also to determining the specific therapy indicated. This article reviews the need for imaging the brain in acute stroke, penumbral pathophysiology, penumbral imaging techniques, as well as current status of various imaging modalities that are being employed to select patients for specific therapeutic approaches.
authors.affiliation: Department of Neurology, University of Missouri-Healthcare Columbia, Columbia, CE 507 Five Hospital Drive, Columbia, Missouri 65212, USA. kumargy@health.missouri.edu
authors.forename: Gyanendra
authors.initials: G
authors.lastname: Kumar
authors.forename: Munish Kumar
authors.initials: MK
authors.lastname: Goyal
authors.forename: Pradeep Kumar
authors.initials: PK
authors.lastname: Sahota
authors.forename: Rajan
authors.initials: R
authors.lastname: Jain
mesh_terms: D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed