title: Three dimensional active contours for the reconstruction of abdominal aortic aneurysms.
abstract: An aneurysm is a gradual and progressive ballooning of a blood vessel due to wall degeneration. Rupture of abdominal aortic aneurysm (AAA) constitutes a significant portion of deaths in the US. In this study, we describe a technique to reconstruct AAA geometry from CT images in an inexpensive and streamlined fashion. A 3D reconstruction technique was implemented with a GUI interface in MATLAB using the active contours technique. The lumen and the thrombus of the AAA were segmented individually in two separate protocols and were then joined together into a hybrid surface. This surface was then used to obtain the aortic wall. This method can deal with very poor contrast images where the aortic wall is indistinguishable from the surrounding features. Data obtained from the segmentation of image sets were smoothed in 3D using a Support Vector Machine technique. The segmentation method presented in this paper is inexpensive and has minimal user-dependency in reconstructing AAA geometry (lumen and wall) from patient image sets. The AAA model generated using this segmentation algorithm can be used to study a variety of biomechanical issues remaining in AAA biomechanics including stress estimation, endovascular stent-graft performance, and local drug delivery studies.
authors.affiliation: Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, AZ 85721, USA.
authors.forename: Avinash
authors.initials: A
authors.lastname: Ayyalasomayajula
authors.forename: Andrew
authors.initials: A
authors.lastname: Polk
authors.forename: Anirban
authors.initials: A
authors.lastname: Basudhar
authors.forename: Samy
authors.initials: S
authors.lastname: Missoum
authors.forename: Lavi
authors.initials: L
authors.lastname: Nissim
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Vande Geest
mesh_terms: D001012:Aorta, Abdominal / Q000000981:diagnostic imaging* / Q000503:physiopathology; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008955:Models, Cardiovascular; D014057:Tomography, X-Ray Computed / Q000379:methods*