title: [Locomotion and posture disabilities in Down syndrome].
abstract: Down syndrome is the most common of the non-hereditary genetic syndromes causing mental retardation. In addition to the phenotype characteristics, the syndrome is accompanied by multi-system pathological conditions, both congenital and acquired. These conditions involve the abnormal function of the musculo-skeletal system and affect movement in general and gait component more specifically. The abnormal gait develops from early childhood and continues into adulthood. This review focuses on the characteristics of this syndrome as concerning the damage to the lower extremities and trunk and the typical gait patterns.
authors.affiliation: Department of Orthopedics B, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv. amirhaim@gmail.com
authors.forename: Amir
authors.initials: A
authors.lastname: Haim
authors.forename: Anat
authors.initials: A
authors.lastname: Lahav
authors.forename: Tamir
authors.initials: T
authors.lastname: Pritsch
authors.forename: Michael
authors.initials: M
authors.lastname: Drexler
authors.forename: Ziva
authors.initials: Z
authors.lastname: Yizhar
mesh_terms: D000328:Adult; D004314:Down Syndrome / Q000235:genetics / Q000503:physiopathology*; D020234:Gait Ataxia / Q000209:etiology*; D005838:Genotype; D006801:Humans; D008124:Locomotion / Q000502:physiology*; D009069:Movement Disorders / Q000209:etiology; D011187:Posture