Microbial transformation of a monoterpene, geraniol, by the marine-derived fungus Hypocrea sp.
Geraniol (1) is the biogenetic precursor of a number of monoterpenes. We tested various marine-derived microorganisms to determine their ability to biotransform 1. Only Hypocrea sp. was capable of transforming 1 into its oxidized derivative, 1,7-dihydroxy-3,7-dimethyl-(E)-oct- 2-ene (2). The structure of the metabolite obtained was assigned on the basis of detailed spectroscopic data analyses.
Leutou
Alain S
AS
Department of Chemistry, Pukyong National University, Busan 608-737, Korea.
Yang
Guohua
G
Nenkep
Viviane N
VN
Siwe
Xavier N
XN
Feng
Zhile
Z
Khong
Thang T
TT
Choi
Hong Dae
HD
Kang
Jung Sook
JS
Son
Byeng Wha
BW
D000080462:Acyclic Monoterpenes; D001711:Biotransformation; D035901:Hypocrea / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D039821:Monoterpenes / Q000737:chemistry / Q000378:metabolism*; D012623:Seawater / Q000382:microbiology*; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism*
D000080462:Acyclic Monoterpenes; D039821:Monoterpenes; D013729:Terpenes; C007836:geraniol