[Associations of waist circumference and body mass index with hypoadiponectinemia in older adults in major cities in China].
OBJECTIVE
To assess and compare the associations of body mass index (BMI) and waist circumference with plasma adiponectin levels in older adults in major Chinese cities.


METHODS
A total of 2049 adults aged 60 - 96 years from 18 major cities of the China National Nutrition and Health Survey in 2002 were included. Plasma adiponectin concentrations were measured and the associations of adiponectin with waist circumference and BMI were analyzed.


RESULTS
Adiponectin concentrations increased with increasing age and were higher in women than in men. Adiponectin concentrations decreased with increasing BMI and waist circumference. After adjusting for age and sex, the adiponectin concentration decreased 15%, 26% and 28% in the 2nd the 3rd and the 4th BMI quartile groups, and 25%, 31% and 35% for the 2nd, 3rd and 4th in waist circumference quartiles, respectively, relative to the values in the corresponding 1st quartiles. One standard deviation (SD) increase in BMI and waist circumference was associated with 13% and 15% decrease in the adiponectin concentrations, respectively. After adjusting for waist circumference, BMI was no longer significantly associated with adiponectin while the association between waist circumference and adiponectin remained significant after adjusting for BMI. Odds ratios for hypoadiponectinemia were 1.46 (95% CI: 1.32 - 1.62) and 1.32 (95% CI: 1.19 - 1.47) corresponding to 1 SD increase in waist circumference and BMI, respectively.


CONCLUSIONS
The association between waist circumference and adiponectin is stronger than the association between BMI and adiponectin in older Chinese adults. This implies that adiponectin level is more correlated with visceral obesity than with whole body obesity.
Zhuo
Qin
Q
Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Wang
Zhiqiang
Z
Fu
Ping
P
Piao
Jianhua
J
Tian
Yuan
Y
Xu
Jie
J
Yang
Xiaoguang
X
D052242:Adiponectin / Q000097:blood*; D000368:Aged; D015992:Body Mass Index; D002681:China; D002947:Cities; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055105:Waist Circumference
D052242:Adiponectin