title: [Reproducibility of the fetal nasal bone measurement by means of bidimensional and three-dimensional ecography during the second trimester of the pregnancy].
abstract: OBJECTIVE
  The utility of the valuation-measurement of the nasal bone in the prognosis of chromosomopaties during the second trimester of the pregnancy is demonstrated.
  
  
  OBJECTIVE
  To evaluate the repeatability of nasal bone measurement during second trimester with bidimensional and three-dimensional sonography.
  
  
  METHODS
  Nasal bone was measured in 50 single pregnancies. First observer carried out two measures of nasal bone with bidimensional sonography, and 1 measure with three-dimensional sonography. Second observer carried out just one measure with bidimensional sonography (2D) and just another one with three-dimensional sonography (3D). We studied the intraobserver variability with 2D sonography, and the interobserver variability with 2D and 3D sonography.
  
  
  RESULTS
  2D-sonography: nasal bone measurement showed excellent intraobserver correlation with a correlation coefficient of 0,87 (CI 95%: 0,78-0,93) and a little means difference of 0,18 (SD: 0,74). Indeed, there was a good interobserver correlation with a correlation coefficient of 0,92 (CI 95%: 0,85-0,95), and a means difference of 0,14 (SD: 0,56). 3D-sonography: there was a acceptable interobserver correlation with correlation coefficient of 0,70 (CI 95%: 0,52-0,82).
  
  
  CONCLUSIONS
  Nasal bone measurement is highly reproducible by means of bidimensional sonography while using three-dimensional sonography, the results are just acceptable.
authors.affiliation: Departamento de Obstetricia y Ginecología, Hospital Universitario Santa Cristina, Madrid, España.
authors.forename: Virginia
authors.initials: V
authors.lastname: Engels Calvo
authors.forename: Ignacio
authors.initials: I
authors.lastname: Zapardiel Gutiérrez
authors.forename: Javier
authors.initials: J
authors.lastname: Valero de Bernabé
authors.forename: Luís
authors.initials: L
authors.lastname: San Frutos Llorente
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Bajo Arenas
mesh_terms: D000328:Adult; D000886:Anthropometry; D005260:Female; D005865:Gestational Age; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000706:statistics & numerical data; D009666:Nose / Q000000981:diagnostic imaging* / Q000196:embryology*; D015588:Observer Variation; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D015203:Reproducibility of Results; D016216:Ultrasonography, Prenatal / Q000379:methods / Q000706:statistics & numerical data