title: Correction of adjuvant arthritis with delphinium extracts and alkaloids.
abstract: Antiinflammatory effects of water-alcohol extracts and sum of alkaloids from the aerial part of delphinium under conditions of immune inflammation caused by Freund's complete adjuvant were comparable to activity of orthophen, a classical antiinflammatory drug. Normalizing effects of the studied extracts on hematological and biochemical parameters were demonstrated.
authors.affiliation: Laboratory of Phytopharmacology, Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Russia. ilz@pharm.tsu.ru
authors.forename: Yu V
authors.initials: YV
authors.lastname: Nesterova
authors.forename: T N
authors.initials: TN
authors.lastname: Povetieva
authors.forename: Yu G
authors.initials: YG
authors.lastname: Nagornyak
authors.forename: N I
authors.initials: NI
authors.lastname: Suslov
authors.forename: T V
authors.initials: TV
authors.lastname: Vetoshkina
authors.forename: T I
authors.initials: TI
authors.lastname: Andreeva
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000627:therapeutic use*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000627:therapeutic use*; D001169:Arthritis, Experimental / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D031882:Delphinium / Q000737:chemistry*; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D005121:Extremities; D005620:Freund's Adjuvant / Q000494:pharmacology*; D006940:Hyperemia / Q000139:chemically induced / Q000188:drug therapy; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use*; D051381:Rats
chemical_list: D000470:Alkaloids; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D005620:Freund's Adjuvant