[Glycosaminoglycanes of cartilage tissue of rats after the mechanical trauma: the influence of low-molecular fraction from the cord blood and blood of dairy calves].
Influence of low-molecular fraction (to 5 kDa) from cord blood (FCB) compared with "Actovegin" derived from the blood of veal calves on the content of the matrix polysaccharide components from and proteins of the cartilage connecting tissue after the mechanical trauma was investigated. It is established, that intramuscular administration of FCB essentially stimulates the accumulation of the basic components of the matrix: hexosamine, uronic acid, hyaluronic acid, chondroitinsulfate and heparin, and also the most important components of structural proteins in the cartilage regenerate of the rat knee joint.
Gulevskiĭ
A K
AK
Grishchenko
V I
VI
Ivanov
E G
EG
D000818:Animals; D002358:Cartilage, Articular / Q000187:drug effects / Q000293:injuries / Q000378:metabolism*; D002417:Cattle; D016326:Extracellular Matrix Proteins / Q000378:metabolism; D005312:Fetal Blood / Q000737:chemistry*; D050724:Fractures, Cartilage / Q000188:drug therapy* / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism*; D006418:Heme / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000627:therapeutic use; D008297:Male; D064235:Matrilin Proteins; D008970:Molecular Weight; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014020:Tissue Extracts / Q000302:isolation & purification / Q000627:therapeutic use*
D016326:Extracellular Matrix Proteins; D006023:Glycoproteins; D006025:Glycosaminoglycans; D064235:Matrilin Proteins; D014020:Tissue Extracts; D006418:Heme; C015646:Actovegin