title: Influenza virus B-associated hemophagocytic syndrome and recurrent pericarditis in a patient with systemic lupus erythematosus.
abstract: We report a 24-year-old male with systemic lupus erythematosus (SLE) who developed influenza virus B-associated hemophagocytic syndrome and cardiac tamponade. Although the patient's general condition improved after steroid pulse therapy and pericardiocentesis, pericardial effusion re-accumulated. Colchicine and aspirin were administered, together with prednisolone, after which no further relapses occurred. This was a rare case of severe influenza-associated hemophagocytic syndrome and steroid-resistant pericardial effusion in an SLE patient.
authors.affiliation: Department of Internal Medicine and Rheumatology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan. yoshirohorai0518@qmed.hosp.go.jp
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Horai
authors.forename: Tomoya
authors.initials: T
authors.lastname: Miyamura
authors.forename: Soichiro
authors.initials: S
authors.lastname: Takahama
authors.forename: Koshiro
authors.initials: K
authors.lastname: Sonomoto
authors.forename: Masataka
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ando
authors.forename: Rumi
authors.initials: R
authors.lastname: Minami
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Eiichi
authors.initials: E
authors.lastname: Suematsu
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D009981:Influenza B virus; D007251:Influenza, Human / Q000150:complications*; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000473:pathology; D008297:Male; D010493:Pericarditis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D001241:Aspirin; D003078:Colchicine