Use of 5-aminolevulinic acid for visualization and resection of a benign pediatric brain tumor.
5-Aminolevulinic acid has been used successfully to facilitate resection of adult malignant gliomas. The authors report their experience in the treatment of a 9-year-old girl who underwent fluorescence-guided resection of a right temporal lobe pleomorphic xanthoastrocytoma using 5-aminolevulinic acid. Intraoperatively, the residual tumor fluoresced, allowing for better visualization. No serious side effects or complications occurred.
Ruge
John R
JR
Department of Neurosurgery, Advocate Lutheran General Children's Hospital, Park Ridge, Chicago, Illinois, USA. jruge@voyager.net
Liu
Jonathan
J
D000622:Aminolevulinic Acid / Q000009:adverse effects; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D002648:Child; D017029:Epilepsy, Complex Partial / Q000209:etiology; D005260:Female; D005453:Fluorescence; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000379:methods*; D025321:Surgery, Computer-Assisted; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery
D000622:Aminolevulinic Acid