Recovery of succinic acid from fermentation broth.
Succinic acid is of high interest as bio-feedstock for the chemical industry. It is a precursor for a variety of many other chemicals, e.g. 1,4-butandiol, tetrahydrofuran, biodegradable polymers and fumaric acid. Besides optimized production strains and fermentation processes it is indispensable to develop cost-saving and energy-effective downstream processes to compete with the current petrochemical production process. Various methods such as precipitation, sorption and ion exchange, electrodialysis, and liquid-liquid extraction have been investigated for the recovery of succinic acid from fermentation broth and are reviewed critically here.
Kurzrock
Tanja
T
Institute of Biochemical Engineering, Technische Universität München, Boltzmannstr. 15, 85748, Garching, Germany.
Weuster-Botz
Dirk
D
D001709:Biotechnology / Q000379:methods*; D011232:Chemical Precipitation; D005285:Fermentation; D007474:Ion Exchange; D019802:Succinic Acid / Q000302:isolation & purification*; D014462:Ultrafiltration
D019802:Succinic Acid