[Intrauterine misoprostol for the prevention of bleeding cesarean].
OBJECTIVE
To evaluate efficacy of misoprostol by intrauterine route for the prevention of the obstetrical hemorrhage and to know its effects collaterals.


METHODS
Clinical and randomized test with 200 patients to those who one took place to them Caesarean. The Group A was applied placebo and the group B misoprostol (group B; 800 microg) intrauterine, after the birth of its newborns. The necessity of additional uterotonics was compared, loss of hemoglobin and hematocrit, and the effects collaterals.


RESULTS
In group B it diminished the necessity of additional uterotonics to 50% and the loss of hemoglobin in 39.6%. In the group greater loss of 3 was registered g of hemoglobin in 13 versus 3% of the patients. With respect to the hematocrit, its loss was reduced in 40.6%. The patients in those who the hematocrit in more fell than 10%, registered themselves in 7 versus 1% cases. The effects collaterals were few and not so serious.


CONCLUSIONS
The intrauterine combination of misoprostol and oxitocin diminishes the postcaesarean sanguineous loss and has brings about few effects collaterals.
Quiroga Díaz
Ricardo
R
Hospital de Ginecología y Obstetricia de Monterrey.
Cantú Mata
Reynaldo
R
Tello Gutiérrez
Héctor E
HE
Puente Villalobos
Mireya
M
Montemayor Garza
Rogelio
R
Martínez Mendoza
Araceli
A
D000328:Adult; D002585:Cesarean Section / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D016595:Misoprostol / Q000008:administration & dosage*; D010120:Oxytocics / Q000008:administration & dosage*; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006473:Postpartum Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D011247:Pregnancy; D014599:Uterus
D010120:Oxytocics; D016595:Misoprostol