Total synthesis of the 2,6-sialylated immunoglobulin G glycopeptide fragment in homogeneous form.
The 2,6-sialylated tridecasaccharide 1 associated with the Fc fragment of intravenous immunoglobulin has been synthesized.
Wang
Ping
P
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065, USA.
Zhu
Jianglong
J
Yuan
Yu
Y
Danishefsky
Samuel J
SJ
D006020:Glycopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000276:immunology*; D007141:Immunoglobulin Fc Fragments / Q000737:chemistry*; D016756:Immunoglobulins, Intravenous / Q000737:chemistry*; D011134:Polysaccharides / Q000138:chemical synthesis* / Q000737:chemistry / Q000276:immunology*
D006020:Glycopeptides; D007141:Immunoglobulin Fc Fragments; D016756:Immunoglobulins, Intravenous; D011134:Polysaccharides