title: Phenylpropanoid glycosides from Heterosmilax erythrantha and their antioxidant activity.
abstract: By various chromatographic methods, one new phenylpropanoid glycoside, heterosmilaside (1), two known phenylpropanoid glycosides, helonioside B (2), and 2',6'-diacetyl-3,6-diferuloyl sucrose (3), and three known flavonoids, isoquercetin (4), quercetin-3-O-beta-D-glucuronopyranoside (5), and quercetin-3-O-(2''-alpha-L-rhamnopyranosyl)-beta-D-glucuronopyranoside (6) were isolated from the methanolic extract of the aerial part of Heterosmilax erythrantha Baill. Their structures were elucidated on the basis of spectroscopic analyses. All the isolated compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 5 and 6 showed significant antioxidant activity with SC(50) values of 3.7 and 6.5 microg/mL, respectively.
authors.affiliation: Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi, Vietnam.
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Nhiem
authors.forename: Phan
authors.initials: P
authors.lastname: Van Kiem
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
authors.forename: Ninh Khac
authors.initials: NK
authors.lastname: Ban
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Cuong
authors.forename: Bui Huu
authors.initials: BH
authors.lastname: Tai
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D010851:Picrates / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D029642:Smilacaceae / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; D020005:Propanols; C439395:1-phenylpropanol; C004931:1,1-diphenyl-2-picrylhydrazyl