title: Cefuroxime dilution error.
abstract: OBJECTIVE
  To present clinical findings of a cluster of cases of inadvertent high-dose intracameral cefuroxime injection after uneventful phacoemulsification cataract surgery.
  
  
  METHODS
  Six eyes of 6 patients (mean age 68.33 years, range 61-75, 4 male, 2 female) were operated on the same day by the same surgeon. At the end of surgery, 3 mg in 0.1 mL cefuroxime (30 mg/mL, Zinnat, GlaxoSmithKline) was erroneously injected into anterior chamber of 6 eyes. Incorrect dilution of cefuroxime was noticed at the end of operation day.
  
  
  RESULTS
  The 6 patients were followed up very closely every day during the first week. No adverse reaction or inflammation was observed at postoperative examination. All patients achieved 20/20 or better vision at the end of the first week.
  
  
  CONCLUSIONS
  Inadvertent intracameral (3 mg in 0.1 mL) cefuroxime injection did not cause any detectable adverse effect on ocular tissues.
authors.affiliation: Gozmer Eye Center, Denizli, Turkey. yasarsakarya@yahoo.com
authors.forename: Yasar
authors.initials: Y
authors.lastname: Sakarya
authors.forename: Rabia
authors.initials: R
authors.lastname: Sakarya
mesh_terms: D000368:Aged; D000867:Anterior Chamber; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002444:Cefuroxime / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D009877:Endophthalmitis / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008508:Medication Errors; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D019999:Pharmaceutical Solutions; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D019999:Pharmaceutical Solutions; D002444:Cefuroxime