title: Simultaneous vertical guided bone regeneration and guided tissue regeneration in the posterior maxilla using recombinant human platelet-derived growth factor: a case report.
abstract: This clinical case report describes and demonstrates successful use of recombinant human platelet-derived growth factor (rhPDGF-BB) in conjunction with autogenous bone, anorganic bone mineral, and barrier membranes to reconstruct severe alveolar bone defects. A combined sinus augmentation and vertical alveolar ridge augmentation was successfully performed. In addition, a significant amount of periodontal bone gain was achieved in close apposition to a previously denuded root surface, which is significant from a periodontal standpoint, given the possibility of vertical periodontal regeneration.
authors.affiliation: Loma Linda University, Loma Linda, Calif, USA. istvan@implant.hu
authors.forename: Istvan
authors.initials: I
authors.lastname: Urban
authors.forename: Nicholas
authors.initials: N
authors.lastname: Caplanis
authors.forename: Jaime L
authors.initials: JL
authors.lastname: Lozada
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery; D000540:Alveolar Ridge Augmentation; D001861:Bone Regeneration / Q000187:drug effects*; D018786:Bone Substitutes; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008437:Maxilla / Q000601:surgery; D008443:Maxillary Sinus / Q000601:surgery*; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000494:pharmacology; D014716:Vertical Dimension
chemical_list: D018786:Bone Substitutes; D010982:Platelet-Derived Growth Factor; D011994:Recombinant Proteins