title: The medical and surgical treatment of glaucoma.
abstract: BACKGROUND
  Ongoing demographic changes in Europe are heightening the importance of adequate treatment for glaucoma, a disorder that is markedly more common in the elderly.
  
  
  METHODS
  A selective search for relevant literature, including Cochrane Reviews and the guidelines of the European Glaucoma Society, regarding the topical and surgical treatment of glaucoma.
  
  
  RESULTS
  It is recommended that the intraocular pressure (IOP) should be lowered by 20% to 50% from its baseline value, depending on the extent of already existing damage, the rate of progression, the baseline IOP, and the age of the patient. Topical monotherapy can lower the IOP by 15% to 30%. The success rate of filtration surgery has risen because of the intraoperative application of topical antimetabolites and currently ranges from 50% to 90%, depending on the study.
  
  
  CONCLUSIONS
  The goal of glaucoma treatment is to protect the patient from blindness and visual impairment while keeping the treatment-related decline in quality of life to a minimum. Any type of glaucoma treatment, be it medical or surgical, must further this aim in consideration of the situation of the individual patient.
authors.affiliation: Zentrum für Augenheilkunde der Universität Köln, Köln, Germany, Thomas.Dietlein@uk-koeln.de
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Dietlein
authors.forename: Manuel M
authors.initials: MM
authors.lastname: Hermann
authors.forename: Jens F
authors.initials: JF
authors.lastname: Jordan
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D005901:Glaucoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D009798:Ocular Hypertension / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*
chemical_list: D000959:Antihypertensive Agents