title: Optical coherence tomography of macular thickness after biaxial vs coaxial microincision clear corneal cataract surgery.
abstract: OBJECTIVE
  To evaluate macular thickness changes after biaxial microincision versus coaxial small incision cataract surgery using optical coherence tomography (OCT).
  
  
  METHODS
  This prospective, randomized, marked study comprised 70 patients (70 eyes) undergoing biaxial microincision surgery or conventional coaxial phacoemulsification. Patients were evaluated by Stratus OCT preoperatively and 1 day, 4 weeks, and 8 weeks postoperatively. Best-corrected visual acuity (BCVA), phacoemulsification power, and effective phacoemulsification time (EPT) were evaluated.
  
  
  RESULTS
  In the biaxial group, median foveal thickness changed from 160 microm preoperatively to 168 microm 8 weeks postoperatively (p=0.018), while median macular volume increased from 2.43 mm3 to 2.57 mm3 (p<0.001). In the coaxial group, median foveal thickness increased from 164 microm preoperatively to 170 microm 8 weeks postoperatively (p=0.082), while median macular volume changed from 2.45 mm3 to 2.55 mm3 (p<0.001). No significant differences in the intraindividual increase of foveal thickness and macular volume were found between groups at 8 weeks. A statistically significant difference between groups was found in median foveal thickness at day 1 postoperatively (p=0.027). No significant differences between groups in median macular volume were found at day 1 or at 4 and 8 weeks postoperatively. Median phacoemulsification power was 7.1% and EPT 2.4 seconds in the biaxial group versus 10.6% and 3.2 seconds in the coaxial group (p<0.001 and p=0.078).
  
  
  CONCLUSIONS
  No clinically relevant differences in foveal thickness or macular volume were observed after biaxial microincision and coaxial small incision clear corneal cataract surgery. The blood-retinal barrier did not seem to be influenced by either procedure.
authors.affiliation: Department of Ophthalmology, Johannes Gutenberg-University, Mainz - Germany. Sab.Schmitz@t-online.de
authors.forename: Sabine
authors.initials: S
authors.lastname: Kurz
authors.forename: Frank
authors.initials: F
authors.lastname: Krummenauer
authors.forename: Hagen
authors.initials: H
authors.lastname: Thieme
authors.forename: H Burkhard
authors.initials: HB
authors.lastname: Dick
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001813:Blood-Retinal Barrier; D003315:Cornea / Q000601:surgery*; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D008266:Macula Lutea / Q000473:pathology*; D008269:Macular Edema / Q000175:diagnosis* / Q000517:prevention & control; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology