title: [Evaluation of antibiotic curative treatments in a French orthopedic surgery unit].
abstract: BACKGROUND
  The aim of this study was to evaluate the technical quality and the relevance of antibiotics used in an orthopedic unit.
  
  
  METHODS
  A prospective and descriptive assessment was made of patients hospitalized in the orthopedic surgery department of our general hospital, receiving antimicrobial therapy. The relevance of antibiotics was evaluated using as a reference local guidelines previously validated by the antibiotics committee.
  
  
  RESULTS
  During the period of study, 37 of the 249 hospitalized patients received antibiotics (14.9 %). The reasons for hospitalization were mainly lower limb trauma (38 %) and an infectious disease (35 %). Hospital-acquired infections accounted for 16.2 % of antibiotic prescriptions. During the study, we observed that the dose regimen was inappropriate in 9 % of the cases, that the expected length of treatment was not indicated (76 %), and that the mode of administration was not mentioned in 8 % of the cases. Twenty five percent of combinations were not relevant. Finally, 27.3 % of prescriptions were not in conformity with guidelines.
  
  
  CONCLUSIONS
  The quality and relevance of antibiotics used as curative treatments in the orthopedic surgery unit seem satisfactory for the dose regimen, the route and dose of administration and combinations used. We identified a few points which need to be improved: update and improvement of local antibiotherapy guidelines, promotion of training sessions for new prescribers in the institution.
authors.affiliation: Commission des antibiotiques, centre hospitalier général d'Avranches-Granville, rue des Menneries, BP 629, 50406 Granville cedex, France. guy-claude.borderan@ch-avranches-granville.fr
authors.forename: G-C
authors.initials: GC
authors.lastname: Borderan
authors.forename: L
authors.initials: L
authors.lastname: Mignot
authors.forename: J
authors.initials: J
authors.lastname: Bonnan
authors.forename: P
authors.initials: P
authors.lastname: Faure
authors.forename: S
authors.initials: S
authors.lastname: Blanc
authors.forename: I
authors.initials: I
authors.lastname: Lelievre
authors.forename: E
authors.initials: E
authors.lastname: Piednoir
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D011307:Drug Prescriptions / Q000592:standards / Q000706:statistics & numerical data; D005260:Female; D005602:France; D006757:Hospital Units; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D010818:Practice Patterns, Physicians'; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents