The role of tetraspanins in the pathogenesis of infectious diseases.
Tetraspanin proteins on host cells are involved in the pathogenesis of infectious diseases at different stages. In this review, we will focus on tetraspanins expressed in the immune system and the role they play in the defense to viral, bacterial, parasitic and fungal infections.
van Spriel
Annemiek B
AB
Department of Tumor Immunology (TIL 278), Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands. avanspriel@scientist.com
Figdor
Carl G
CG
D000818:Animals; D015703:Antigens, CD / Q000378:metabolism*; D001419:Bacteria / Q000472:pathogenicity; D001424:Bacterial Infections / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D005658:Fungi / Q000472:pathogenicity; D006801:Humans; D007239:Infections / Q000209:etiology* / Q000276:immunology / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism*; D010271:Parasites / Q000472:pathogenicity; D010272:Parasitic Diseases / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D014777:Virus Diseases / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D014780:Viruses / Q000472:pathogenicity
D015703:Antigens, CD; D008565:Membrane Proteins