[Regional audit on fluoroquinolones usage in the hospital and the community: are these antibiotics over-used?].
OBJECTIVE
The ecological impact of an over-use or a mis-use of fluoroquinolones (FQs) appears of great importance according to published data. With the objective to set up a regional antibiotic stewardship program, we conducted a regional audit on FQs usage.


METHODS
[corrected] Ninety general practionners and 15 health care facilities participated to this prospective study. Overall, 511 prescriptions were evaluated (276 from hospital physicians and 235 [46%] from general practionners). The compliance of FQs prescription with national recommendations and with a regional referential was assessed. This regional referential was established in order to preserve FQs.


RESULTS
Only 14,3% of the prescriptions complied with the regional referential, even if the choice of FQs were in accordance with national recommendations in 56,8% of the prescriptions. Urinary tract infections (mostly non-complicated) were the most common indication for FQs prescription.


CONCLUSIONS
Analysis of FQs prescriptions shows that there is a significant potential for FQs preservation in Franche-Comté.
Leroy
J
J
Service des maladies infectieuses et tropicales, pôle gestion du risque infectieux et sanitaire, CHU de Besançon, 25030 Besançon, France.
Patry
I
I
Faure
C
C
Ariskina
E
E
Gaume
J-P
JP
Hénon
T
T
Ruyer
O
O
Faller
J-P
JP
Hoen
B
B
Bertrand
X
X
Talon
D
D
D000890:Anti-Infective Agents / Q000008:administration & dosage*; D054869:Clinical Audit; D024841:Fluoroquinolones / Q000008:administration & dosage*; D058006:General Practice; D019983:Guideline Adherence; D006761:Hospitals; D006801:Humans; D010818:Practice Patterns, Physicians'; D055553:Prescription Drugs
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D055553:Prescription Drugs