title: The clinical and imaging characteristics of breast cancers in patients with interstitial mammoplasty.
abstract: OBJECTIVE
  The aims of this study are to demonstrate the clinical characteristics and various imaging findings of breast cancers in patients with interstitial mammoplasty.
  
  
  METHODS
  A total of six patients, who had breast cancer and had received liquid silicone or paraffin injection for augmentation, were included in this study. Mammography, ultrasonography, dynamic breast MRI, and PET/CT were performed for 5, 3, 6, and 2 patients, respectively. The clinical course was reviewed, and the imaging findings were retrospectively evaluated according to the ACR BI-RADS atlas.
  
  
  RESULTS
  The mean maximal diameter of the detected breast cancers on enhanced breast MRI was 5.5 cm (range 4.8-7.1 cm). Although the breast cancers were all of a large size, subjective breast symptoms exhibited in only four of six patients. Mammographic examinations exhibited variable associate findings such as skin thickening, ipsilateral volume increase, and increase densities, but could not demonstrate main breast masses. A few sonographic examinations exhibited masses with associate findings such as skin thickening. On breast MRI, enhancing breast cancers with associate findings were detected in all the patients. On PET-CT, breast cancers and distant metastases were detected.
  
  
  CONCLUSIONS
  Breast cancers in these patients were detected at the advanced stage. Dynamic breast MRI was useful for detecting breast cancer in these patients. Mammography failed to demonstrate the breast cancer, but cancer detection was facilitated by associated findings: skin thickening, asymmetric volume increase, and increased density.
authors.affiliation: Department of Radiology, The Catholic University of Korea, 505 Banpo-dong, Seocho-ku, Seoul, 137-040, Korea.
authors.forename: Bong Joo
authors.initials: BJ
authors.lastname: Kang
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Jae Jeong
authors.initials: JJ
authors.lastname: Choi
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Lee
authors.forename: Eun Suk
authors.initials: ES
authors.lastname: Cha
authors.forename: Hyun Suk
authors.initials: HS
authors.lastname: Kim
authors.forename: Chang Suk
authors.initials: CS
authors.lastname: Park
authors.forename: In Young
authors.initials: IY
authors.lastname: Whang
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007267:Injections; D008279:Magnetic Resonance Imaging; D016462:Mammaplasty / Q000009:adverse effects* / Q000379:methods; D008327:Mammography; D008875:Middle Aged; D010232:Paraffin / Q000008:administration & dosage*; D012189:Retrospective Studies; D012828:Silicones / Q000008:administration & dosage*; D016217:Ultrasonography, Mammary
chemical_list: D012828:Silicones; D010232:Paraffin