title: [Hypersensitity pneumonitis in a greenhouse rose grower].
abstract: A 54-year-old woman presented with chronic cough. She had been engaged in growing roses in plastic greenhouses. Chest CT scan showed bilateral diffuse ground-glass attenuation. Bronchoalveolar lavage fluid demonstrated the increase of total cell counts with predominant lymphocyte cells, and transbronchial lung biopsy specimen revealed lymphocyte alveolitis with granuloma. Precipitating antibody against the extract of the Penicillium species obtained in the greenhouses was detected by the double immunodiffusion test, which led to a diagnosis of hypersensitivity pneumonitis caused by Penicillium species. This case suggests the risk of hypersensitivity pneumonitis caused by fungi in closed spaces with high temperature and humidity such as greenhouses.
authors.affiliation: Department of Respiratory Medicine, the University of Tokyo Hospital.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Amano
authors.forename: Munehiro
authors.initials: M
authors.lastname: Enomoto
authors.forename: Masashi
authors.initials: M
authors.lastname: Bando
authors.forename: Masanori
authors.initials: M
authors.lastname: Kawakami
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D000382:Agricultural Workers' Diseases / Q000209:etiology; D000542:Alveolitis, Extrinsic Allergic / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology; D010407:Penicillium / Q000276:immunology; D027826:Rosa