title: Coarctation of the aorta treated with the Advanta V12 large diameter stent: acute results.
abstract: OBJECTIVE
  To report on the early results of treatment of coarctation of the aorta by dilation with a new polytetrafluoroethylene covered stent.
  
  
  BACKGROUND
  Transcatheter dilation of aortic coarctation carries the risk of aneurysm or rupture. Covered stent implantation reduces this risk but requires a large delivery system. The Advanta V12 LD covered stent is premounted and requires a 9-11 Fr delivery system.
  
  
  METHODS
  Covered stents on balloons of a diameter sufficient to anchor the stent in the coarctation were implanted using the smallest available delivery system. Secondary dilation with larger diameter balloons was performed until the pressure gradient was <20 mm Hg and the stent was opposed to the aortic wall.
  
  
  RESULTS
  Twenty-five patients with aortic coarctation underwent stent implantation. Coarctation diameter increased from (6.3 + or - 3.5) mm to (14.4 + or - 2.3) mm (P < 0.0001). Peak pressure gradient decreased from (25.3 + or - 11.6) mm Hg to (2.5 + or - 3.0) mm Hg (P < 0.0001). The stent achieved the desired diameter in all cases. There were no complications. At short-term median follow-up of 4.9 months, all patients are alive and well with no evidence of recoarctation or aneurysm.
  
  
  CONCLUSIONS
  These initial results show that the covered Advanta V12LD stent is safe and effective in the immediate treatment of coarctation of the aorta through a low profile delivery system of 8-11 Fr. Long term follow up is required.
authors.affiliation: Pediatric Cardiac Catheterization, Schneider Children's Medical Center Israel, Kaplan 14, Petach Tikva, Israel. elchananb@bezeqint.net
authors.forename: Elchanan
authors.initials: E
authors.lastname: Bruckheimer
authors.forename: Einat
authors.initials: E
authors.lastname: Birk
authors.forename: Raul
authors.initials: R
authors.lastname: Santiago
authors.forename: Tamir
authors.initials: T
authors.lastname: Dagan
authors.forename: Carlos
authors.initials: C
authors.lastname: Esteves
authors.forename: Carlos A C
authors.initials: CA
authors.lastname: Pedra
mesh_terms: D000293:Adolescent; D000328:Adult; D001017:Aortic Coarctation / Q000628:therapy*; D006328:Cardiac Catheterization; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D020099:Coated Materials, Biocompatible; D006801:Humans; D011138:Polytetrafluoroethylene; D019919:Prosthesis Implantation; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D020099:Coated Materials, Biocompatible; D011138:Polytetrafluoroethylene