Candida albicans isolated from human fungaemia induces apoptosis in an experimental endocarditis model.
Candida albicans is the most common fungal pathogen known to cause endovascular infections, such as vascular catheter sepsis, infections of vascular prostheses and infective endocarditis. A C. albicans isolate was used to determine the apoptotic potential of the fungus in a rat endocarditis model. This study confirms the ability of C. albicans to induce apoptosis in myocardial tissue.
Hernández-Cañaveral
Iván
I
Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Becerra
Gerardo
G
Jiménez-Cordero
Alberto
A
Michel
Jean-Baptiste
JB
Plascencia
Arturo
A
Domínguez-Hernández
Miguel
M
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002176:Candida albicans / Q000472:pathogenicity*; D002177:Candidiasis / Q000382:microbiology*; D004195:Disease Models, Animal; D004696:Endocarditis / Q000382:microbiology*; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D051381:Rats; D013997:Time Factors