title: Diterpene esters and phenolic compounds from Sapium insigne (ROYLE) BENTH. ex HOOK. fil.
abstract: From the leaves of Sapium insigne (ROYLE) BENTH. ex HOOK. fil., two new phorbol derivatives, such as 16-hydroxyphorbol-16-acetate (4) and 4beta-deoxy-16-hydroxyphorbol-16-acetate (5) along with twelve known phenolic compounds such as 3-O-caffeoyl quinic acid (1), 1-O-galloyl-beta-D-glucose (2), 1,3-di-O-galloyl-beta-D-glucose (3), rutin (6), 1,3,4,6-tetra-O-galloyl-beta-D-glucose (7), quercetin (8), guaijaverin (9), nicotiflorin (10), scopolin (11), methyl gallate (12), corilagin (13) and 1,3,6-tri-O-galloyl-beta-D-glucose (14) were isolated. All of these compounds have been isolated for the first time from this plant.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.
authors.forename: Hari Prasad
authors.initials: HP
authors.lastname: Devkota
authors.forename: Purusotam
authors.initials: P
authors.lastname: Basnet
authors.forename: Shoji
authors.initials: S
authors.lastname: Yahara
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification*; D010703:Phorbol Esters / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C546238:16-hydroxyphorbol-16-acetate; C546239:4beta-deoxy-16-hydroxyphorbol-16-acetate; D004224:Diterpenes; D004952:Esters; D010636:Phenols; D010703:Phorbol Esters