title: Validation of analytical methods and instrumentation for beryllium measurement: review and summary of available guides, procedures, and protocols.
abstract: This document provides a listing of available sources that can be used to validate analytical methods and/or instrumentation for beryllium determination. A literature review was conducted of available standard methods and publications used for method validation and/or quality control. An annotated listing of the articles, papers, and books reviewed is given in the Appendix. Available validation documents and guides are listed therein; each has a brief description of application and use. In the referenced sources, there are varying approaches to validation and varying descriptions of the validation process at different stages in method development. This discussion focuses on validation and verification of fully developed methods and instrumentation that have been offered for use or approval by other laboratories or official consensus bodies such as ASTM International, the International Standards Organization, the International Electrotechnical Commission, and the Association of Official Analytical Chemists. This review was conducted as part of a collaborative effort to investigate and improve the state of validation for measuring beryllium in the workplace and the environment. Documents and publications from the United States and Europe are included.
authors.affiliation: Savannah River National Laboratory, Aiken, South Carolina 29808, USA. amy.ekechukwu@srnl.doe.gov
authors.forename: Amy
authors.initials: A
authors.lastname: Ekechukwu
authors.forename: Warren
authors.initials: W
authors.lastname: Hendricks
authors.forename: Kenneth T
authors.initials: KT
authors.lastname: White
authors.forename: Albert
authors.initials: A
authors.lastname: Liabastre
authors.forename: Melecita
authors.initials: M
authors.lastname: Archuleta
authors.forename: Mark D
authors.initials: MD
authors.lastname: Hoover
mesh_terms: D001608:Beryllium / Q000032:analysis*; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods*; D017408:Guidelines as Topic; D016273:Occupational Exposure / Q000032:analysis*; D015203:Reproducibility of Results
chemical_list: D001608:Beryllium