title: Anastomoses of the lower gastrointestinal tract.
abstract: Patients with gastrointestinal anastomoses are treated by physicians of multiple specialties, including gastroenterologists, radiologists and surgeons. This Review provides an overview of the surgical principles and techniques involved in the creation of lower intestinal anastomoses, including some of the mechanisms of healing. Anatomical configurations of small and large bowel anastomoses are illustrated. Stapled, hand-sewn, and sutureless anstomotic techniques are also discussed. Laparoscopy has revolutionized our approach to surgery of the gastrointestinal tract and we describe some of the current and future minimally invasive techniques for creating anastomoses. The article also highlights principles important in minimizing potential short-term and long-term complications such as anastomotic leaks and strictures. Common risk factors for dehiscence include poor nutrition, immunosuppression, microvascular disease, obesity and technical errors. An evidence-based review of perioperative and postoperative management of intestinal anastomoses is provided to help optimize patient care. The routine use of nasogastric tubes and mechanical bowel preparation has no documented benefits and could contribute to postoperative complications. Upcoming strategies that might prove useful to reinforce anastomoses are also reviewed.
authors.affiliation: Department of Surgery, Weill Cornell Medical College, 525 East 68th Street, New York, NY 10021, USA. doctorgovind@ gmail.com
authors.forename: Govind
authors.initials: G
authors.lastname: Nandakumar
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Stein
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Michelassi
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D003251:Constriction, Pathologic / Q000209:etiology; D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D010535:Laparoscopy; D041741:Lower Gastrointestinal Tract / Q000601:surgery*; D017792:Surgical Stapling; D013529:Surgical Wound Dehiscence / Q000209:etiology; D013536:Suture Techniques; D014945:Wound Healing / Q000502:physiology