title: Pathologic diagnosis and resection of suspicious thoracic metastases in patients with cervical cancer through thoracotomy or video-assisted thoracic surgery.
abstract: OBJECTIVE
  The purpose of this study was to clarify the role of resection for suspicious thoracic metastasis in cervical cancer patients with thoracotomy or video-assisted thoracic surgery (VATS).
  
  
  METHODS
  A retrospective study was performed involving patients with primary and recurrent cervical cancer who underwent surgical resections for suspicious thoracic metastatic lesions at a single academic institution between January 2003 and February 2009.
  
  
  RESULTS
  Twenty-three pulmonary resections were performed on 21 patients via thoracotomies (n=10), VATS (n=11), and thoracotomies following VATS (n=2). All suspicious pulmonary lesions were completely resected in all 3 surgical groups. A total of 49 surgical procedures were performed, as follows: 25 wedge resections, 9 lobectomies, 12 mediastinal lymph node dissections, 1 segmentectomy, 1 diaphragmatic resection, and 1 pleurectomy. The pathologic evaluation revealed metastasis from cervical cancer, primary lung cancer, no pathologic abnormality, and tuberculosis in 14, 7, 2, and 1 of the surgical specimens, respectively; 1 patient had primary lung cancer and mediastinal lymph node metastasis from cervical cancer. Different pathologic diagnoses were rendered in 6 patients compared to the image-based diagnoses. After pulmonary metastasectomy, 2 patients died from the disease, 3 patients were alive with disease, and 16 patients were alive without disease, with a median follow-up of 16 months (range, 2-67 months).
  
  
  CONCLUSIONS
  Resection of suspicious thoracic metastasis with thoracotomy or VATS permits accurate pathologic diagnosis and favorable curative resection in selected patients with cervical cancer.
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Korea. mclim@ncc.re.kr
authors.forename: Myong Cheol
authors.initials: MC
authors.lastname: Lim
authors.forename: Hyun-Sung
authors.initials: HS
authors.lastname: Lee
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Seo
authors.forename: Moon Soo
authors.initials: MS
authors.lastname: Kim
authors.forename: Joo-Young
authors.initials: JY
authors.lastname: Kim
authors.forename: Jae Ill
authors.initials: JI
authors.lastname: Zo
authors.forename: Sang Yoon
authors.initials: SY
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery*; D008875:Middle Aged; D012189:Retrospective Studies; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*