title: Microbial transformation of a monoterpene, geraniol, by the marine-derived fungus Hypocrea sp.
abstract: Geraniol (1) is the biogenetic precursor of a number of monoterpenes. We tested various marine-derived microorganisms to determine their ability to biotransform 1. Only Hypocrea sp. was capable of transforming 1 into its oxidized derivative, 1,7-dihydroxy-3,7-dimethyl-(E)-oct- 2-ene (2). The structure of the metabolite obtained was assigned on the basis of detailed spectroscopic data analyses.
authors.affiliation: Department of Chemistry, Pukyong National University, Busan 608-737, Korea.
authors.forename: Alain S
authors.initials: AS
authors.lastname: Leutou
authors.forename: Guohua
authors.initials: G
authors.lastname: Yang
authors.forename: Viviane N
authors.initials: VN
authors.lastname: Nenkep
authors.forename: Xavier N
authors.initials: XN
authors.lastname: Siwe
authors.forename: Zhile
authors.initials: Z
authors.lastname: Feng
authors.forename: Thang T
authors.initials: TT
authors.lastname: Khong
authors.forename: Hong Dae
authors.initials: HD
authors.lastname: Choi
authors.forename: Jung Sook
authors.initials: JS
authors.lastname: Kang
authors.forename: Byeng Wha
authors.initials: BW
authors.lastname: Son
mesh_terms: D000080462:Acyclic Monoterpenes; D001711:Biotransformation; D035901:Hypocrea / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D039821:Monoterpenes / Q000737:chemistry / Q000378:metabolism*; D012623:Seawater / Q000382:microbiology*; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000080462:Acyclic Monoterpenes; D039821:Monoterpenes; D013729:Terpenes; C007836:geraniol