In vivo biofilm composition of Aspergillus fumigatus.
The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus during host invasion is reported here for the first time. A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with the aspergillosis pathologies.
Loussert
Céline
C
Electron Microscopy Platform, Institut Pasteur, Paris, France.
Schmitt
Christine
C
Prevost
Marie-Christine
MC
Balloy
Viviane
V
Fadel
Elie
E
Philippe
Bruno
B
Kauffmann-Lacroix
Catherine
C
Latgé
Jean Paul
JP
Beauvais
Anne
A
D000818:Animals; D001232:Aspergillus fumigatus / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D018441:Biofilms / Q000254:growth & development*; D005109:Extracellular Matrix / Q000737:chemistry*; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D008351:Mannans / Q000032:analysis; D051379:Mice; D011134:Polysaccharides / Q000032:analysis
D008351:Mannans; D011134:Polysaccharides; C062157:galactosaminogalactan; C012990:galactomannan; D005690:Galactose