Vitreoretinal dysplasia masquerading as Peters' anomaly.
OBJECTIVE
Vitreoretinal dysplasia is characterized by a congenital bilateral nonattachment of the retina. In some cases, anteroposition of the iris and lens can lead to corneolenticular contact and corneal opacity, masquerading as Peters' anomaly. We report 3 cases of vitreoretinal dysplasia initially diagnosed as Peters' anomaly.


METHODS
Case report.


RESULTS
Case 1: In a 3-year-old boy with bilateral corneal opacities, high frequency ultrasound showed iridolenticular adherences as in Peters' anomaly, but color Doppler imaging of the posterior pole revealed a bilateral total retinal detachment. Case 2: In an 18-month-old boy with bilateral corneal opacity and dense cataract, ultrasound revealed a shallow anterior chamber and bilateral vitreous hemorrhage with retinal detachment. Case 3: In a 6-month-old girl with bilateral central corneal opacity, shallow anterior chamber, iridocorneal synechiae, and a cataract, ultrasound revealed a total retinal detachment in the right eye, and was uncertain in the left eye. Corneal transplantation was attempted in the left eye, but a retinal detachment was discovered peroperatively. There were associated central nervous system anomalies.


CONCLUSIONS
Vitreoretinal dysplasia is a potentially evolving disease and can lead to anterior chamber thinning, corneal opacity, and secondary glaucoma. Anterior and posterior segment ultrasound is essential to fix the correct diagnosis and prognosis.
Martinet
Virginie
V
Paediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Dureau
Pascal
P
Bergès
Olivier
O
Caputo
Georges
G
D000869:Anterior Eye Segment / Q000002:abnormalities* / Q000000981:diagnostic imaging; D002675:Child, Preschool; D003318:Corneal Opacity / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005124:Eye Abnormalities / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012160:Retina / Q000002:abnormalities*; D012163:Retinal Detachment / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color; D014822:Vitreous Body / Q000002:abnormalities*