title: Nonadherence and the transition to adulthood.
abstract: 1. Rates of nonadherence among pediatric transplant recipients are as high as 50% to 65%, and this places adolescent transplant recipients at increased risk. 2. Adherence to immunosuppressant medications is a critical factor in the transition process as poor medication adherence is associated with an increased risk of poor long-term health outcomes. 3. Before transferring to adult-centered care, the pediatric transplant recipient should demonstrate adequate regimen knowledge and self-management skills. 4. Future research is needed to identify factors and interventions that affect long-term health outcomes in pediatric transplant recipients, including factors related to nonadherence and the successful transfer from pediatric care to adult-centered care.
authors.affiliation: University of Michigan, 1924 Taubman Center, Ann Arbor, MI 48109-5318, USA. emfred@med.umich.edu
authors.forename: Emily M
authors.initials: EM
authors.lastname: Fredericks
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003266:Continuity of Patient Care; D006085:Graft Survival / Q000187:drug effects*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016031:Liver Transplantation / Q000534:rehabilitation; D055118:Medication Adherence; D010372:Pediatrics; D012307:Risk Factors; D012648:Self Care / Q000523:psychology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents