title: Effect of early intervention on 8-year growth status of low-birth-weight preterm infants.
abstract: OBJECTIVE
  To examine the impact of early educational experience at age 8 years on child growth status. The Infant Health and Development Program has shown positive impacts to age 8 years on intelligence and adaptive functioning of larger preterm infants.
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  Home and center based.
  
  
  METHODS
  Three hundred seventy-seven intervention (INT) and 608 nonintervention (NI) children, stratified by birth-weight categories 2001 to 2500 g and 2000 g or less. Intervention Educational intervention from nursery discharge until age 3 years.
  
  
  METHODS
  Eight-year weight, height, head circumference, and body mass index.
  
  
  RESULTS
  Complete data were available for 313 INT children and 491 NI children. Adjusting for child birth weight, birth-weight category, treatment group x birth-weight category interaction, sex, race, and Neonatal Health Index; maternal education and preconception weight; and site, the INT children at age 8 years were significantly taller (127.6 vs 126.6 cm; P = .02) and had a larger head circumference (52.5 vs 52.1 cm; P < .001) than the NI children. The prevalence of both overweight (9%) and underweight (4.5%) was the same in both treatment groups. Lighter low-birth-weight INT children had greater 8-year weight (28.0 vs 26.8 kg; P = .02), larger head circumference (52.6 vs 52.1 cm; P < .001), and larger height (127.6 vs 126.5 cm; P = .05) compared with their counterparts in the NI group.
  
  
  CONCLUSIONS
  Low-birth-weight preterm children, specifically the lighter low-birth-weight group, who received the Infant Health and Development Program educational intervention were heavier and taller and had greater head circumference compared with NI children in the same birth-weight category.
authors.affiliation: Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA. caseypatrickh@uams.edu
authors.forename: Patrick H
authors.initials: PH
authors.lastname: Casey
authors.forename: Robert H
authors.initials: RH
authors.lastname: Bradley
authors.forename: Leanne
authors.initials: L
authors.lastname: Whiteside-Mansell
authors.forename: Kathleen
authors.initials: K
authors.lastname: Barrett
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Gossett
authors.forename: Pippa M
authors.initials: PM
authors.lastname: Simpson
mesh_terms: D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002508:Cephalometry; D002648:Child; D006801:Humans; D007230:Infant, Low Birth Weight / Q000254:growth & development*; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development*; D010290:Parents / Q000193:education*; D010353:Patient Education as Topic