title: [Trends in colorectal cancer in Spain from 1951-2007 and alcohol and cigarette consumption].
abstract: OBJECTIVE
  To analyze trends in colorectal cancer in Spain from 1951-2007, and their relationship with alcohol and cigarette consumption.
  
  
  METHODS
  We performed a correlation analysis between incidence, mortality and potential years of life lost rates, the mean age at death, and per capita consumption of alcohol and cigarettes with a time span of 15 years.
  
  
  RESULTS
  In contrast with the tendency in other countries, the incidence of colorectal cancer steadily increased in both genders. Mortality increased from 1951-2000 and then stabilized in men and decreased in women. Years of potential life lost showed a similar pattern to mortality, while the mean age at death continuously increased during the study period in both genders. For alcohol consumption, the coefficients in both genders ranged from 0.41 to 0.67, with the highest incidence values being obtained for Zaragoza. For cigarette consumption, the correlation coefficients showed positive values close to 1 in the incidence in Zaragoza and Navarre, and somewhat lower values for mortality and potential years of life lost in both genders.
  
  
  CONCLUSIONS
  Legislative measures on alcohol and cigarette consumption should be urgently applied by authorities in the field of education and health promotion to decrease the incidence, mortality and potential years of life lost rates for colorectal cancer.
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España. lmbprado@us.es
authors.forename: Luis
authors.initials: L
authors.lastname: Béjar
authors.forename: Miguel
authors.initials: M
authors.lastname: Gili
authors.forename: Julio
authors.initials: J
authors.lastname: López
authors.forename: Gloria
authors.initials: G
authors.lastname: Ramírez
authors.forename: Juan
authors.initials: J
authors.lastname: Cabanillas
authors.forename: Concepción
authors.initials: C
authors.lastname: Cruz
mesh_terms: D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology* / Q000331:legislation & jurisprudence / Q000517:prevention & control; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D003627:Data Interpretation, Statistical; D004032:Diet; D005260:Female; D006266:Health Education; D006293:Health Promotion; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D050177:Overweight; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology* / Q000331:legislation & jurisprudence; D000074606:Smoking Prevention; D013030:Spain / Q000453:epidemiology; D013997:Time Factors