title: 18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging findings of primary intracranial histiocytic sarcoma in a dog.
abstract: A 10-year-old, neutered male, Maltese dog presented with a three week history of intention tremor, right hind limb rigidity, poor coordination, and occasional circling to the left. On magnetic resonance imaging (MRI) of the brain, a mass was identified in the right occipital lobe and cerebellum. Three weeks after the initial MRI scan, we performed an (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) of the brain. The FDG-PET demonstrated areas of hypermetabolism in the right occipital lobe, cerebellum, pons, and medulla oblongata. When the standardized uptake value was calculated, the hypermetabolic lesion was higher than the gray matter values. The anatomical location of the hypermetabolic lesion was more precisely identified by the PET-MRI fusion images. The dog was definitively diagnosed as a primary histiocytic sarcoma of the brain. This is the first report of PET findings of an intracranial histiocytic sarcoma in a dog.
authors.affiliation: BK21 Program of Basic and Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwang-jin-gu, Seoul.
authors.forename: Byeong-Teck
authors.initials: BT
authors.lastname: Kang
authors.forename: Chul
authors.initials: C
authors.lastname: Park
authors.forename: Jong-Hyun
authors.initials: JH
authors.lastname: Yoo
authors.forename: Su-Hyun
authors.initials: SH
authors.lastname: Gu
authors.forename: Dong-Pyo
authors.initials: DP
authors.lastname: Jang
authors.forename: Young-Bo
authors.initials: YB
authors.lastname: Kim
authors.forename: Eung-Je
authors.initials: EJ
authors.lastname: Woo
authors.forename: Dae-Young
authors.initials: DY
authors.lastname: Kim
authors.forename: Zang-Hee
authors.initials: ZH
authors.lastname: Cho
authors.forename: Hee-Myung
authors.initials: HM
authors.lastname: Park
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D019788:Fluorodeoxyglucose F18; D054747:Histiocytic Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D049268:Positron-Emission Tomography / Q000662:veterinary*
chemical_list: D019788:Fluorodeoxyglucose F18