title: Ependymoblastoma in a Japanese Black heifer.
abstract: An 18-month-old, Japanese Black heifer had ananastasia over a two-week period. The heifer was euthanized and necropsied. Grossly, a brown and soft mass was found in the left cerebellar hemisphere, which originated from the fourth ventricle in the pons. Multiple papillary masses were also found on the wall of the fourth ventricle. There was massive dilatation of the cerebral aqueduct, and also in the third and lateral ventricles. Histologically, the neoplastic cells formed numerous ependymoblastic rosettes and perivascular pseudorosettes. In the fourth ventricle, the normal ependymal cells were replaced by papillary proliferation of the neoplastic cells. Ultrastructually, the neoplastic cells had a feature differentiating to the ependymal cell showing a few basal bodies in the cytoplasm and connecting to adjacent cells with junctional complexes. We diagnosed the present case as ependymoblastoma with its origins in the fourth ventricle.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, Kagoshima University, 1-21-24, Korimoto, Kagoshima 890-0065, Japan. miyoshi@agri.kagoshima-u.ac.jp
authors.forename: Noriaki
authors.initials: N
authors.lastname: Miyoshi
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kawaguchi
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Uchida
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yasuda
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D005260:Female; D017599:Neuroectodermal Tumors / Q000473:pathology / Q000662:veterinary*