The impacts of type 2 diabetes mellitus on bone markers in the elderly Thai women.
A comparison study of bone turnover between the diabetic type 2 and the non-diabetic patients was conducted by using the age matching technique. The bone markers of the diabetic type 2 patients showed CTx = 0.48 ng/ml, NMID osteocalcin = 24.62 ng/ml and PINP = 38.61 ng/ml. All study parameters of bone markers were higher than the control group. Thus, the diabetic cases with high bone turnover assuredly predisposed to osteoporosis. The bone change consistently monitored particularly in the diabetic cases could prevent osteoporosis. The high calcium diets and regular exercises were recommended for the diabetic patients.
Pooruk
Phasook
P
Department of Family Medicine, Buddhachinaraj Hospital, Phitsanulok, Thailand.
Kittimanon
Nipat
N
Janthorn
Pilanthana
P
Bunyaratavej
Narong
N
D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D015519:Bone Density; D003094:Collagen / Q000097:blood*; D024042:Collagen Type I / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011347:Procollagen / Q000097:blood*; D013785:Thailand
D015415:Biomarkers; D024042:Collagen Type I; D010446:Peptide Fragments; D011347:Procollagen; C047202:procollagen Type I N-terminal peptide; D015675:Osteocalcin; D003094:Collagen