title: Generalized discoid lupus erythematosus.
abstract: A 79-year-old woman presented with a four-year history of generalized, erythematous, indurated plaques on the malar areas, back, and extremities. The lesions had been recalcitrant in the past to topical glucocorticoid therapy. A skin biopsy specimen was diagnostic of discoid lupus erythematosus (DLE). A minority of patients with DLE progress to develop systemic lupus erythematosus although generalized DLE is more frequently associated with systemic involvement than is limited disease. Standard therapy of cutaneous lupus includes broad spectrum sunscreens, topical and intralesional glucocorticoids, and antimalarial agents.
authors.affiliation: Department of Dermatology, New York University, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Farley-Loftus
authors.forename: Matthew
authors.initials: M
authors.lastname: Mahlberg
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Merola
authors.forename: Henry J
authors.initials: HJ
authors.lastname: Votava
authors.forename: Shane
authors.initials: S
authors.lastname: Meehan
authors.forename: Jennifer
authors.initials: J
authors.lastname: Stein
authors.forename: Jerome L
authors.initials: JL
authors.lastname: Shupack
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000473:pathology*