F-18 FDG-PET imaging of dysembryoplastic neuroepithelial tumor-like astrocytoma.
Cerebral astrocytoma needs to be distinguished from dysembryoplastic neuroepithelial tumor (DNT) when a well-demarcated, cortically based and pseudo-cystic tumor with minimal mass effect is demonstrated on magnetic resonance imaging. We report an unusual case of DNT-like astrocytoma. 18F fluoro-deoxy-glucose (FDG) positron emission tomography showed a focal increase of FDG uptake in a deep part of the tumor. Histologic examination revealed predominantly microcystic change with oligodendrocyte-like cells, leading to a diagnosis of DNT. However, increased cellularity and nuclear atypia of astrocytes within the tumor were conspicuous as for DNT. Four years after excision, tumor recurrence was detected. FDG-positron emission tomography is useful for identifying the malignant potential of DNT-like astrocytoma.
Shinohara
Yuki
Y
Department of Radiology, Research Institute of Brain and Blood Vessels, Akita, Japan. shino-y@akita-noken.go.jp
Kinoshita
Toshibumi
T
Kinoshita
Fumiko
F
Moroi
Junta
J
Yoshida
Yasuji
Y
Nakazato
Yoichi
Y
D000328:Adult; D001254:Astrocytoma / Q000000981:diagnostic imaging*; D003399:Craniotomy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D018302:Neoplasms, Neuroepithelial / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography
D019788:Fluorodeoxyglucose F18