title: Seven years of chronological changes of serum chromium levels after Metasul metal-on-metal total hip arthroplasty.
abstract: Although many authors have reported the serum concentrations of metal ions in patients who had metal-on-metal coupling prostheses, most of the studies were not longitudinal, and the follow-up periods were short. We evaluated the longitudinal changes of serum chromium levels in 44 patients who had undergone unilateral metal-on-metal total hip arthroplasty for a minimum of 7 years postoperatively. Although there was a consistent increase in the mean serum chromium level until 3 years after implantation, there was little difference in the levels from years 3 to 7 postoperatively. Although the serum chromium concentration was low throughout postoperative follow-up for 7 years in about 25% of patients, the serum chromium level stayed high or showed gradual elevation in 16.3% of our patients.
authors.affiliation: Department of Orthopaedic Surgery, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan.
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Maezawa
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nozawa
authors.forename: Takahito
authors.initials: T
authors.lastname: Yuasa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Aritomi
authors.forename: Keiji
authors.initials: K
authors.lastname: Matsuda
authors.forename: Katsuo
authors.initials: K
authors.lastname: Shitoto
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000601:surgery; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation*; D002857:Chromium / Q000097:blood*; D002858:Chromium Alloys; D005260:Female; D005271:Femur Head Necrosis / Q000601:surgery; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008670:Metals; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery
chemical_list: D002858:Chromium Alloys; D008670:Metals; D002857:Chromium