Practical experience in some aspects of bone markers.
The biochemical bone markers are the firmly approved means for bone assessment with high accuracy for detecting the status of bone functions in real time. The values obtained from the bone markers are continuously fluctuating. The interpretation, thus, needs to be based on the controlled clinical criteria such as fasting blood venous puncture required at 8:00-9:00, gender age and information of previously medicated treatments. These characteristic values are compared with the normal ones derived by the healthy young adult persons. The bone markers are essentially requested when diagnosing the bone state. Both formation and resorption markers represent bone turnover. The low values of bone markers are the signs of being low bone turnover as well as the high values show high bone turnover. The bone markers strongly support the diagnosis of bone metabolism, bone diseases and the evaluation of medication and bone metastasis.
Bunyaratavej
Narong
N
Department of Orthopaedic Surgery, Siriraj Hospital, Mahidol University, Bangkok, Thailand. todrnarong@yahoo.com
D015415:Biomarkers / Q000378:metabolism*; D015519:Bone Density / Q000502:physiology; D001846:Bone Development / Q000502:physiology*; D001847:Bone Diseases / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism*; D006801:Humans
D015415:Biomarkers