Cytomegalovirus retinitis associated with Good's syndrome.
OBJECTIVE
To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.


METHODS
A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.


RESULTS
Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.


CONCLUSIONS
CMV retinitis can be associated with Good's syndrome.
Mateo-Montoya
Aranzazu
A
Ophthalmology Service, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Stanescu
Dinu
D
Wolff
Benjamin
B
Sahel
José-Alain
JA
Bonnel
Sébastien
S
D000212:Acyclovir / Q000008:administration & dosage; D000361:Agammaglobulinemia / Q000150:complications*; D000998:Antiviral Agents / Q000008:administration & dosage; D001082:Aqueous Humor / Q000821:virology; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D017726:Cytomegalovirus Retinitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004279:DNA, Viral / Q000235:genetics; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D015774:Ganciclovir / Q000008:administration & dosage; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D013577:Syndrome; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*; D014792:Visual Acuity; D014822:Vitreous Body
D000998:Antiviral Agents; D004279:DNA, Viral; D015774:Ganciclovir; D000212:Acyclovir