title: Granzyme A is a proinflammatory protease.
authors.forename: Julián
authors.initials: J
authors.lastname: Pardo
authors.forename: Markus M
authors.initials: MM
authors.lastname: Simon
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Froelich
mesh_terms: D019943:Amino Acid Substitution; D017209:Apoptosis / Q000235:genetics / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000201:enzymology / Q000276:immunology*; D020169:Caspases / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D004249:DNA Damage / Q000276:immunology*; D004260:DNA Repair / Q000235:genetics / Q000276:immunology*; D015870:Gene Expression; D053804:Granzymes / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D020014:K562 Cells; D020125:Mutation, Missense; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D017434:Protein Structure, Tertiary / Q000502:physiology
chemical_list: C499320:PARP1 protein, human; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases; D053804:Granzymes; C509212:GZMA protein, human; D020169:Caspases