title: Nerve fiber layer thickness in exudative age-related macular degeneration in Japanese patients.
abstract: OBJECTIVE
  To examine the peripapillary retinal nerve fiber (RNFL) thickness in Japanese patients with two major forms of exudative age-related macular degeneration (AMD), i.e., typical AMD and polypoidal choroidal vasculopathy (PCV).
  
  
  METHODS
  This is a prospective observational consecutive study. One hundred patients diagnosed with unilateral exudative AMD, with the fellow eyes free of exudative change, were included. Peripapillary RNFL thickness was measured using three-dimensional Fourier-domain optical coherence tomography (3D-OCT). Peripapillary RNFL thickness was compared between the affected eyes and fellow eyes in 100 patients.
  
  
  RESULTS
  RNFL thickness in the eyes with exudative AMD did not differ significantly from the fellow eyes. There was also no association between the lesion size and the peripapillary RNFL thickness.
  
  
  CONCLUSIONS
  There is no relationship between exudative AMD and peripapillary RNFL thickness in Japanese patients.
authors.affiliation: Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yuda
authors.forename: Yuji
authors.initials: Y
authors.lastname: Inoue
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tomidokoro
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tamaki
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yanagi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000208:ethnology; D002829:Choroid / Q000098:blood supply; D005122:Exudates and Transudates; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D008268:Macular Degeneration / Q000175:diagnosis* / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000208:ethnology; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence