title: Juvenile xanthogranuloma with bilateral ocular involvement: complete response after treatment with vinblastine: case report.
abstract: OBJECTIVE
  To present an infant with bilateral ocular and skin involvement by juvenile xanthogranuloma and the results of treatment with vinblastine.
  
  
  METHODS
  Analysis of the clinical and histopathologic data and the results of the treatment.
  
  
  RESULTS
  After 14 months' evolution with no response to other treatments, the lesions responded to a course of vinblastine (6 mg/m2/weekly, corrected for weight), which was followed by a maintenance treatment for 52 weeks.
  
  
  CONCLUSIONS
  The treatment protocol used in the present case may prove useful for similar patients. We found no other report describing these results.
authors.affiliation: Oncology Unit, "Superiora Sor María Ludovica" Children's Hospital, La Plata - Argentina. danielpo@netverk.com.ar
authors.forename: Daniel
authors.initials: D
authors.lastname: Pollono
authors.forename: Marta
authors.initials: M
authors.lastname: Galan
authors.forename: Adriana
authors.initials: A
authors.lastname: Curuchet
authors.forename: Ricardo
authors.initials: R
authors.lastname: Drut
authors.forename: Agustina
authors.initials: A
authors.lastname: Pollono
authors.forename: Jacinto
authors.initials: J
authors.lastname: Rodriguez
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005128:Eye Diseases / Q000188:drug therapy / Q000209:etiology*; D007839:Functional Laterality; D006801:Humans; D007223:Infant; D008297:Male; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology; D014747:Vinblastine / Q000627:therapeutic use*; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000188:drug therapy
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine