title: Time sequence of bone healing around two implant systems in minipigs: preliminary histologic results.
abstract: The aim of this study was to evaluate the early phases of bone healing around two different implant surfaces. For this purpose, four minipigs were used. Implants with rough titanium surfaces (ITI sandblasted/acid-etched and Branemark TiUnite) were placed in the maxillae of the animals and sacrifice was scheduled in such a way that healing times of 3 days, 1 week, 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6 weeks, and 7 weeks were obtained. Histologic analysis revealed that a similar pattern was observed in the phases of bone healing around both types of implants between 3 days and 7 weeks. This pattern consisted of the replacement of blood clot and bone debris with a provisional connective tissue in the first few weeks and with mineralized tissue and marrow spaces later on. Both rough surfaces allowed for "contact osteogenesis" to take place. (Int J Periodontics Restorative Dent 2009;29:549-555.).
authors.affiliation: Dental Clinic, Department of Medicine, Surgery and Dentistry, Milano, Italy. daniela.carmagnola@unimi.it
authors.forename: Daniela
authors.initials: D
authors.lastname: Carmagnola
authors.forename: Silvio
authors.initials: S
authors.lastname: Abati
authors.forename: Alessandro
authors.initials: A
authors.lastname: Addis
authors.forename: Giovanni
authors.initials: G
authors.lastname: Ferrieri
authors.forename: Matteo
authors.initials: M
authors.lastname: Chiapasco
authors.forename: Eugenio
authors.initials: E
authors.lastname: Romeo
authors.forename: Giorgio
authors.initials: G
authors.lastname: Vogel
mesh_terms: D000818:Animals; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D008297:Male; D016348:Osseointegration; D013499:Surface Properties; D013552:Swine; D013556:Swine, Miniature; D013997:Time Factors
chemical_list: D015921:Dental Implants