Effect of age on changes in anterior chamber depth and volume after laser in situ keratomileusis.
OBJECTIVE
To evaluate the effect of age on anterior chamber depth (ACD) and anterior chamber volume (ACV) after laser in situ keratomileusis (LASIK) for myopia.


METHODS
Department of Ophthalmology, Keio University School of Medicine, and a private clinic, Tokyo, Japan.


METHODS
In this retrospective study, patients who had uneventful LASIK for myopia or myopic astigmatism were divided into 2 groups: younger (younger than 40 years) and older (40 years and older). Central corneal thickness, central corneal true net power, ACV, and central ACD were measured using a rotating Scheimpflug camera preoperatively and 1 month postoperatively. These parameters were compared between the 2 groups.


RESULTS
The study evaluated 161 eyes of 83 patients (mean age 34.5 years +/- 8.3 [SD]). The decreases in central ACD and ACV after LASIK were statistically significant in the younger group (P<.0001 and P = .0050, respectively) but not in the older group.


CONCLUSIONS
Central ACD and the ACV decreased significantly after LASIK in younger patients (<40 years) but not in older patients, indicating that age influences changes in ACD and ACV after LASIK.
Nishimura
Ryo
R
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Negishi
Kazuno
K
Dogru
Murat
M
Saiki
Megumi
M
Arai
Hiroyuki
H
Toda
Ikuko
I
Yamaguchi
Takefumi
T
Tsubota
Kazuo
K
D000328:Adult; D000375:Aging / Q000502:physiology*; D000867:Anterior Chamber / Q000473:pathology*; D001251:Astigmatism / Q000601:surgery; D003315:Cornea / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery; D011184:Postoperative Period; D057234:Preoperative Period; D012189:Retrospective Studies; D055815:Young Adult