title: Glycogen synthase kinase 3 in the world of cell migration.
abstract: Glycogen synthase kinase 3 (GSK3) is one of the few master switch kinases that regulate many aspects of cell functions. Recent studies on cell polarization and migration have shown that GSK3 is also essential for proper regulation of these processes. GSK3 influences cell migration as one of the regulators of the spatiotemporally controlled dynamics of the actin cytoskeleton, microtubules, and cell-to-matrix adhesions. In this mini-review, the effects of GSK3 on these three aspects of cell migration will be discussed.
authors.affiliation: Department of Biological Sciences, Florida International University, Miami, FL 33199, USA.
authors.forename: Tong
authors.initials: T
authors.lastname: Sun
authors.forename: Marbelys
authors.initials: M
authors.lastname: Rodriguez
authors.forename: Leung
authors.initials: L
authors.lastname: Kim
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology; D002465:Cell Movement / Q000235:genetics / Q000502:physiology*; D003599:Cytoskeleton / Q000235:genetics / Q000378:metabolism; D005109:Extracellular Matrix / Q000378:metabolism / Q000502:physiology; D038362:Glycogen Synthase Kinase 3 / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008870:Microtubules / Q000378:metabolism / Q000502:physiology; D008954:Models, Biological
chemical_list: D038362:Glycogen Synthase Kinase 3