Sun proteins enlighten nuclear movement in development.
Regulation of nuclear movement is a critical event in neurogenesis and neuronal migration during brain development. In this issue of Neuron, Zhang et al. identify a role for SUN and the KASH-domain-containing nuclear membrane proteins as the long-sought linker between microtubules and the nucleus during brain development.
Koizumi
Hiroyuki
H
Department of Neurosciences, Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA.
Gleeson
Joseph G
JG
D000818:Animals; D001921:Brain / Q000166:cytology / Q000196:embryology*; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D021381:Protein Transport / Q000235:genetics / Q000502:physiology*
D009687:Nuclear Proteins