title: Etiopathogenesis of Behcet's disease.
abstract: Bechet's disease (BD) is an inflammatory, multi systemic disease with spontaneous remissions and relapses similar to various autoimmune diseases. BD leads to organ damage, including the eyes, skin, joints, etc., which produces various clinical manifestations. The central histopathologic characteristic is systemic vasculitis with perivascular inflammatory infiltrates. The etiopathogenesis is unknown, although immunological abnormalities, possibly induced by susceptible microbiological pathogens, have been postulated.
authors.affiliation: Systemic Autoimmune Diseases Research Unit, HGR #36, Instituto Mexicano del Seguro Social, Puebla, Mexico.
authors.forename: Claudia
authors.initials: C
authors.lastname: Mendoza-Pinto
authors.forename: Mario
authors.initials: M
authors.lastname: García-Carrasco
authors.forename: Mario
authors.initials: M
authors.lastname: Jiménez-Hernández
authors.forename: Cesar
authors.initials: C
authors.lastname: Jiménez Hernández
authors.forename: Carlos
authors.initials: C
authors.lastname: Riebeling-Navarro
authors.forename: Arnulfo
authors.initials: A
authors.lastname: Nava Zavala
authors.forename: Mauricio
authors.initials: M
authors.lastname: Vera Recabarren
authors.forename: Gerard
authors.initials: G
authors.lastname: Espinosa
authors.forename: Javier
authors.initials: J
authors.lastname: Jara Quezada
authors.forename: Ricard
authors.initials: R
authors.lastname: Cervera
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004890:Erythema; D020022:Genetic Predisposition to Disease; D015235:HLA-B Antigens / Q000235:genetics; D059949:HLA-B51 Antigen; D006801:Humans; D008877:Middle East; D007703:Peptidyl-Dipeptidase A / Q000235:genetics; D011110:Polymorphism, Genetic; D011516:Prothrombin / Q000235:genetics; D056647:Systemic Vasculitis; D013927:Thrombosis; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics; D014456:Ulcer
chemical_list: D000305:Adrenal Cortex Hormones; D015235:HLA-B Antigens; D059949:HLA-B51 Antigen; D014409:Tumor Necrosis Factor-alpha; D011516:Prothrombin; C488034:ACE protein, human; D007703:Peptidyl-Dipeptidase A