title: Alternative routes of insulin delivery.
abstract: Parenteral route of insulin administration has been the mode of treatment for all Type 1 diabetics and Type 2 diabetics with complications. Patient compliance has really been a major concern for this route of administration. Several alternative routes of administration are under consideration for effective glycemic control, including oral, inhaled, buccal, nasal, and patch routes. One of the approaches involving inhaled insulin has now reached the market. Several other candidates may reach the market in the near future, the promising one being oral insulin.
authors.affiliation: Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
authors.forename: Ranjith K
authors.initials: RK
authors.lastname: Krishnankutty
authors.forename: Aju
authors.initials: A
authors.lastname: Mathew
authors.forename: Saikiran K
authors.initials: SK
authors.lastname: Sedimbi
authors.forename: Shrikumar
authors.initials: S
authors.lastname: Suryanarayan
authors.forename: Carani B
authors.initials: CB
authors.lastname: Sanjeevi
mesh_terms: D000278:Administration, Buccal; D000280:Administration, Inhalation; D000281:Administration, Intranasal; D000284:Administration, Oral; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004333:Drug Administration Routes; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin