title: The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment.
abstract: Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.
authors.affiliation: Molecular Imaging Program, National Cancer Institute National Institutes of Health, Bethesda, Maryland, USA. bturkbey@yahoo.com
authors.forename: Bariş
authors.initials: B
authors.lastname: Türkbey
authors.forename: David
authors.initials: D
authors.lastname: Thomasson
authors.forename: Yuxi
authors.initials: Y
authors.lastname: Pang
authors.forename: Marcelino
authors.initials: M
authors.lastname: Bernardo
authors.forename: Peter L
authors.initials: PL
authors.lastname: Choyke
mesh_terms: D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009362:Neoplasm Metastasis / Q000175:diagnosis; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000473:pathology