title: Novel system for decarboxylative bromination of alpha,beta-unsaturated carboxylic acids with diacetoxyiodobenzene.
abstract: A simple and mild method for the conversion of varieties of alpha,beta-unsaturated carboxylic acids to the corresponding bromoalkenes using diacetoxyiodobenzene (IBD) in combination with tetraethyl-ammonium bromide (TEAB) at room temperature is discussed. Advantages of this system are short reaction time, easy work up and gave good to excellent yields.
authors.affiliation: Department of Pharmaceutical Chemistry, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Maharashtra, India.
authors.forename: Ravindra Abhykumar
authors.initials: RA
authors.lastname: Fursule
authors.forename: Pravin Onkar
authors.initials: PO
authors.lastname: Patil
authors.forename: Bharti Devaji
authors.initials: BD
authors.lastname: Shewale
authors.forename: Satish Bhaskar
authors.initials: SB
authors.lastname: Kosalge
authors.forename: Prashant Krishnarao
authors.initials: PK
authors.lastname: Deshmukh
authors.forename: Dilip Ashok
authors.initials: DA
authors.lastname: Patil
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D003653:Decarboxylation; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis* / Q000737:chemistry; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D019789:Tetraethylammonium / Q000737:chemistry
chemical_list: D002264:Carboxylic Acids; D006842:Hydrocarbons, Brominated; D007462:Iodobenzenes; D019789:Tetraethylammonium