CD24 gene polymorphism is associated with the disease progression and susceptibility to multiple sclerosis in the Iranian population.
The impact of a single nucleotide polymorphism (SNP) in the CD24 gene on the risk and progression of multiple sclerosis (MS) was investigated in the Iranian population. Our data revealed that the susceptibility and the progression of MS in individuals with the CD24V/V genotype were greater than in those with the CD24A/V and CD24A/A genotypes.
Ronaghi
Mohammad
M
Department of Biology, The University of Isfahan, Isfahan, Iran.
Vallian
Sadeq
S
Etemadifar
Masoud
M
D000704:Analysis of Variance; D051927:CD24 Antigen / Q000235:genetics*; D016009:Chi-Square Distribution; D018450:Disease Progression; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007492:Iran; D009103:Multiple Sclerosis / Q000235:genetics* / Q000503:physiopathology*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D044382:Population Groups / Q000235:genetics
D051927:CD24 Antigen