title: Behavior of bioactive glass-ceramic implanted into long bone defects: a scintigraphic study.
abstract: The purpose of the study was to assess the long-term behavior and incorporation of the bioactive oxyhydroxyapatite glass-ceramic used to fill defects of long bones after curettage of bone cysts in 17 patients. The method of evaluation was a three-phase bone scintigraphy combined with radiographic and clinical evaluation. At a mean follow-up of 7 years, the glass-ceramic material had been completely incorporated. Mean uptake ratio was 1.31+/-0.25 after implantation of glass-ceramic in the metaphyseal region and 2.07+/-0.62 after implantation of glass-ceramic in the diaphyseal region (P<0.05). Mean uptake ratio was 1.40+/-0.30 in patients without persistent pain and 2.07+/-0.69 in patients who complained of pain in the area of synthetic filling (P<0.05). The bioactive glass-ceramic can be implanted into the metaphyseal defects of long bones, but this material is not suitable for filling the diaphyseal defects.
authors.affiliation: Departments of Orthopaedic Surgery, Charles University, University Hospital, Hradec Králové, Czech Republic. sponer.p@seznam.cz
authors.forename: Pavel
authors.initials: P
authors.lastname: Sponer
authors.forename: Karel
authors.initials: K
authors.lastname: Urban
authors.forename: Elen
authors.initials: E
authors.lastname: Urbanová
authors.forename: Karel
authors.initials: K
authors.lastname: Karpas
authors.forename: Pradeep George
authors.initials: PG
authors.lastname: Mathew
mesh_terms: D000293:Adolescent; D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D018786:Bone Substitutes; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000601:surgery*; D002516:Ceramics; D002648:Child; D003475:Curettage; D005260:Female; D006801:Humans; D008297:Male; D016348:Osseointegration; D019736:Prostheses and Implants; D011877:Radionuclide Imaging; D055815:Young Adult
chemical_list: C081271:BAS O glass ceramic; D018786:Bone Substitutes