miRNA control of tumor cell invasion and metastasis.
MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post-translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion, migration and metastasis. In this review, we briefly describe the role of various miRNAs in invasion, migration and metastasis which are essential steps during cancer progression.
Baranwal
Somesh
S
Department of Biochemistry and Molecular Biology, LSU Health Science Center, New Orleans, LA 70112, USA.
Alahari
Suresh K
SK
D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D008954:Models, Biological; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology*; D025521:Tumor Suppressor Proteins / Q000235:genetics
D014408:Biomarkers, Tumor; D035683:MicroRNAs; D025521:Tumor Suppressor Proteins