Intravascular T-cell lymphoma of the vulva, CD30 positive: a case report.
Primary non-Hodgkin's lymphoma involving the vulva is very rare. It affects predominantly the labia major but it can also present as a clitoral mass or can even be located in the Bartholin's gland. Vulvar lymphoma is an aggressive disease. We describe a case of a 48-year-old woman who presented to our hospital with fever and a slow growing mass in the vulva. She had no other clinical symptoms. CT-scan showed no evidence of disease in any other organ or lymph node tissue. A local excision of the mass followed and the final diagnosis was primary intravascular vulvar lymphoma, of T-cell origin, CD30 positive. In general, intravascular lymphomas are clinically and immunophenotypically heterogenous and may represent more than one entity. They are predominantly of B cell lineage, involving most commonly the skin and rarely other systems or organs. Because of the fact that the vulva is a cutaneous site the development of intravascular lymphoma in this region is possible.
Zizi-Sermpetzoglou
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A
Department of Pathology, Tzaneion General Hospital of Pireaus, Pireaus, Greece. adserbet@yahoo.gr
Petrakopoulou
N
N
Tepelenis
N
N
Savvaidou
V
V
Vasilakaki
T
T
D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D019043:Vascular Neoplasms / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000601:surgery