title: [Prevalence of extended-spectrum beta-lactamases of the CTX-M type producing Escherichia coli and Klebsiella pneumoniae in Bretonneau hospitals (CHRU Tours)].
abstract: The CTX-M type extended spectrum beta-lactamases constitute a rapidly growing cluster of enzymes that have disseminated geographically. This study evaluates the prevalence of these enzymes in the university hospital in Tours, in 2007. Twenty-eight strains were studied: 21 Escherichia coli and seven Klebsiella pneumoniae. The gene bla(CTX-M) was detected by real-time PCR for 27 strains. The CTX-M-1 group, including CTX-M-15, was the most frequent CTX-M-type enzyme.
authors.affiliation: Laboratoire de Bactériologie-Virologie, Hôpital Bretonneau, CHRU de Tours, 2 Boulevard Tonnellé, 37044 Tours cedex 9, France.
authors.forename: A
authors.initials: A
authors.lastname: Holstein
authors.forename: A
authors.initials: A
authors.lastname: Grillon
authors.forename: L
authors.initials: L
authors.lastname: Yzon
authors.forename: V
authors.initials: V
authors.lastname: Morange
authors.forename: G
authors.initials: G
authors.lastname: Baty
authors.forename: M-F
authors.initials: MF
authors.lastname: Lartigue
authors.forename: L
authors.initials: L
authors.lastname: Mereghetti
authors.forename: A
authors.initials: A
authors.lastname: Goudeau
authors.forename: P
authors.initials: P
authors.lastname: Lanotte
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D001426:Bacterial Proteins / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D001437:Bacteriuria / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D005602:France / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007710:Klebsiella Infections / Q000453:epidemiology / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013379:Substrate Specificity; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases