title: [Syndrome of cholestasis: modern concepts].
abstract: Definition of cholestasis syndrome is proposed, anatomic and physiological aspects of bile production and excretion are discussed, modern data on etiology and pathogenesis of intra- and extrahepatic chollestasis are presented along with the working classification of its forms. Much attention is given to clinical manifestations of the disease, its laboratory, instrumental, and morphological diagnosis. Major disorders clinically resembling cholestasis syndrome are briefly reviewed. Special emphasis is laid on up-to-date means and methods for the management of the disease.
authors.forename: Ia S
authors.initials: IaS
authors.lastname: Tsimmerman
mesh_terms: D001646:Bile / Q000378:metabolism; D002756:Cholagogues and Choleretics / Q000627:therapeutic use*; D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D019299:Decompression, Surgical / Q000379:methods*; D003938:Diagnostic Techniques, Digestive System; D004781:Environmental Exposure / Q000009:adverse effects; D006801:Humans; D013577:Syndrome
chemical_list: D002756:Cholagogues and Choleretics