Phenylpropanoid glycosides from Heterosmilax erythrantha and their antioxidant activity.
By various chromatographic methods, one new phenylpropanoid glycoside, heterosmilaside (1), two known phenylpropanoid glycosides, helonioside B (2), and 2',6'-diacetyl-3,6-diferuloyl sucrose (3), and three known flavonoids, isoquercetin (4), quercetin-3-O-beta-D-glucuronopyranoside (5), and quercetin-3-O-(2''-alpha-L-rhamnopyranosyl)-beta-D-glucuronopyranoside (6) were isolated from the methanolic extract of the aerial part of Heterosmilax erythrantha Baill. Their structures were elucidated on the basis of spectroscopic analyses. All the isolated compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 5 and 6 showed significant antioxidant activity with SC(50) values of 3.7 and 6.5 microg/mL, respectively.
Nhiem
Nguyen Xuan
NX
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi, Vietnam.
Van Kiem
Phan
P
Minh
Chau Van
CV
Ban
Ninh Khac
NK
Cuong
Nguyen Xuan
NX
Tai
Bui Huu
BH
Kim
Young Ho
YH
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D010851:Picrates / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D029642:Smilacaceae / Q000737:chemistry*
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; D020005:Propanols; C439395:1-phenylpropanol; C004931:1,1-diphenyl-2-picrylhydrazyl