The impact of networks on clinical trials in the United Kingdom.
The conduct of clinical trials in the UK has been affected by the recent introduction of managed clinical networks, clinical research networks and rigorous governance regulations. This commentary considers the challenges that these changes have posed for clinical triallists in the UK, based on experiences derived in the conduct of a multicentre neonatal clinical trial under the conditions that now prevail. We conclude that the considerable skills and knowledge that are now required to be an effective Principal Investigator should be recognised and that application processes, including issuing honorary contracts, should be simplified and centralised.
Ng
Sze May
SM
School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool, UK. M.Ng@liverpool.ac.uk
Weindling
Alan Michael
AM
D035843:Biomedical Research; D002986:Clinical Trials as Topic / Q000379:methods; D006801:Humans; D012107:Research Design; D006113:United Kingdom