title: Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles.
abstract: Quinidine derivative (QD)(2)PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, PR China.
authors.forename: Zi-Qing
authors.initials: ZQ
authors.lastname: Qian
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.forename: Tai-Ping
authors.initials: TP
authors.lastname: Du
authors.forename: Bo-Lun
authors.initials: BL
authors.lastname: Wang
authors.forename: Miao
authors.initials: M
authors.lastname: Ding
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Zhao
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
mesh_terms: D000586:Amination; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D000078183:Oxindoles; D013237:Stereoisomerism
chemical_list: D000588:Amines; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole