title: Intravascular T-cell lymphoma of the vulva, CD30 positive: a case report.
abstract: Primary non-Hodgkin's lymphoma involving the vulva is very rare. It affects predominantly the labia major but it can also present as a clitoral mass or can even be located in the Bartholin's gland. Vulvar lymphoma is an aggressive disease. We describe a case of a 48-year-old woman who presented to our hospital with fever and a slow growing mass in the vulva. She had no other clinical symptoms. CT-scan showed no evidence of disease in any other organ or lymph node tissue. A local excision of the mass followed and the final diagnosis was primary intravascular vulvar lymphoma, of T-cell origin, CD30 positive. In general, intravascular lymphomas are clinically and immunophenotypically heterogenous and may represent more than one entity. They are predominantly of B cell lineage, involving most commonly the skin and rarely other systems or organs. Because of the fact that the vulva is a cutaneous site the development of intravascular lymphoma in this region is possible.
authors.affiliation: Department of Pathology, Tzaneion General Hospital of Pireaus, Pireaus, Greece. adserbet@yahoo.gr
authors.forename: A
authors.initials: A
authors.lastname: Zizi-Sermpetzoglou
authors.forename: N
authors.initials: N
authors.lastname: Petrakopoulou
authors.forename: N
authors.initials: N
authors.lastname: Tepelenis
authors.forename: V
authors.initials: V
authors.lastname: Savvaidou
authors.forename: T
authors.initials: T
authors.lastname: Vasilakaki
mesh_terms: D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D019043:Vascular Neoplasms / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000601:surgery