Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols.
Hamels
Didier
D
Chimie ParisTech (Ecole Nationale Supérieure de Chimie de Paris), Laboratoire Charles Friedel, UMR CNRS 7223, 11 rue P. et M. Curie, 75231 Paris cedex 05, France.
Dansette
Patrick M
PM
Hillard
Elizabeth A
EA
Top
Siden
S
Vessières
Anne
A
Herson
Patrick
P
Jaouen
Gérard
G
Mansuy
Daniel
D
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D005296:Ferrous Compounds / Q000737:chemistry*; D006801:Humans; D045563:Indolequinones / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D000075163:Metallocenes; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry*; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D005296:Ferrous Compounds; D045563:Indolequinones; D000075163:Metallocenes; D010636:Phenols; C068040:quinone methide; C004998:ferrocene