title: Bileaflet mechanical heart valve closing sounds: in vitro classification by phonocardiographic analysis.
abstract: Bileaflet mechanical heart valves, which exhibit hemodynamic performance fairly similar to that of native valves, can be investigated by the analysis of their closing sounds. Signal spectra calculated from the closing sounds are characterized by specific features that are suitable for the functional evaluation of the valves. Five commercial bileaflet mechanical heart valves were studied under different conditions that were simulated in vitro using a Sheffield pulse duplicator for the aortic position. The closing sounds were acquired by means of a phonocardiographic apparatus, analyzed by a specifically implemented algorithm, and were statistically compared. This article was aimed at classifying the investigated valves on the basis of their signal spectra: different profiles were identified, depending on the working conditions; moreover, closing sound reproducibility and intensity allowed the ranking of valve performances with respect to the "noise" produced by valve closure. In particular, results demonstrated which valves were characterized by the lowest noise (i.e., the Medtronic Advantage and St. Jude Regent valves) and which were characterized by the highest reproducibility (OnX, Medtronic Advantage, and St. Jude Regent valves) under the examined experimental conditions.
authors.affiliation: Department of Chemical Process Engineering, University of Padua, Padua, Italy. andrea.bagno@unipd.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Bagno
authors.forename: Federico
authors.initials: F
authors.lastname: Anzil
authors.forename: Roberto
authors.initials: R
authors.lastname: Buselli
authors.forename: Elena
authors.initials: E
authors.lastname: Pesavento
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Tarzia
authors.forename: Vittorio
authors.initials: V
authors.lastname: Pengo
authors.forename: Tomaso
authors.initials: T
authors.lastname: Bottio
authors.forename: Gino
authors.initials: G
authors.lastname: Gerosa
mesh_terms: D001696:Biomechanical Phenomena; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006439:Hemodynamics; D006801:Humans; D008422:Materials Testing; D010701:Phonocardiography; D011474:Prosthesis Design; D012815:Signal Processing, Computer-Assisted; D013016:Sound