title: [Approaches to the treatment of malignant and progressive multiple sclerosis].
abstract: Disease-modifying therapy of multiple sclerosis (MS) with malignant and progressive course of the disease currently is not fully covered at present. Data on the use of some immunosupressors and cytostatics in the treatment of MS with rapid progression of disability are reviewed.
authors.forename: F V
authors.initials: FV
authors.lastname: Avdeev
authors.forename: A N
authors.initials: AN
authors.lastname: Boĭko
mesh_terms: D054697:Cytostatic Agents / Q000627:therapeutic use*; D004185:Disability Evaluation; D018450:Disease Progression; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000534:rehabilitation; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D054697:Cytostatic Agents; D007166:Immunosuppressive Agents