Allergic reactions to human insulin: a review of current knowledge and treatment options.
Although the incidence of insulin allergy decreased after the introduction of recombinant human insulin preparations, it is still a major problem which may be life-threatening in some cases. In this article, we attempted to review current knowledge concerning allergic reactions to human insulin and discuss the available treatment options of insulin allergy.
Akinci
Baris
B
Division of Endocrinology of Metabolism, Department of Internal Medicine, Dokuz Eylul University Medical School, Inciralti, 35340 Izmir, Turkey. baris.akinci@deu.edu.tr
Yener
Serkan
S
Bayraktar
Firat
F
Yesil
Sena
S
D048909:Diabetes Complications / Q000276:immunology / Q000628:therapy; D004342:Drug Hypersensitivity / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D055104:Infusions, Subcutaneous; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives / Q000627:therapeutic use; D007330:Insulin Antibodies / Q000097:blood / Q000276:immunology*
D007004:Hypoglycemic Agents; D007328:Insulin; D007330:Insulin Antibodies