title: F-18 FDG PET/CT showing bilateral breast involvement in acute myeloid leukemia relapse.
abstract: Isolated extramedullary relapse with involvement of the breasts by acute myeloid leukemia (AML) after allogeneic stem cell transplantation is an uncommon event. We here report the case of a 27-year-old female patient, who was diagnosed with high-risk AML (FAB M5, complex karyotype). Fourteen months after successful bone marrow transplantation, she presented with asymptomatic masses in both breasts. Ultrasound-guided biopsy was performed and histopathology revealed relapsing AML. F-18 FDG PET/CT was performed for whole-body staging and intense multifocal uptake was seen in both breasts and in the abdomen. Isolated extramedullary disease recurrence was confirmed by bone marrow biopsy.
authors.affiliation: Institutes of Radiology, Hannover Medical School, Hannover, Germany. c.v.falck@gmx.de
authors.forename: Christian
authors.initials: C
authors.lastname: von Falck
authors.forename: Florian
authors.initials: F
authors.lastname: Laenger
authors.forename: Wolfram H
authors.initials: WH
authors.lastname: Knapp
authors.forename: Michael
authors.initials: M
authors.lastname: Galanski
mesh_terms: D000328:Adult; D001940:Breast / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000000981:diagnostic imaging*; D008327:Mammography; D049268:Positron-Emission Tomography; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D019788:Fluorodeoxyglucose F18