title: Public opinion about the importance of privacy in biobank research.
abstract: Concerns about privacy may deter people from participating in genetic research. Recruitment and retention of biobank participants requires understanding the nature and magnitude of these concerns. Potential participants in a proposed biobank were asked about their willingness to participate, their privacy concerns, informed consent, and data sharing. A representative survey of 4659 U.S. adults was conducted. Ninety percent of respondents would be concerned about privacy, 56% would be concerned about researchers having their information, and 37% would worry that study data could be used against them. However, 60% would participate in the biobank if asked. Nearly half (48%) would prefer to provide consent once for all research approved by an oversight panel, whereas 42% would prefer to provide consent for each project separately. Although 92% would allow academic researchers to use study data, 80% and 75%, respectively, would grant access to government and industry researchers. Concern about privacy was related to lower willingness to participate only when respondents were told that they would receive $50 for participation and would not receive individual research results back. Among respondents who were told that they would receive $200 or individual research results, privacy concerns were not related to willingness. Survey respondents valued both privacy and participation in biomedical research. Despite pervasive privacy concerns, 60% would participate in a biobank. Assuring research participants that their privacy will be protected to the best of researchers' abilities may increase participants' acceptance of consent for broad research uses of biobank data by a wide range of researchers.
authors.affiliation: Genetics and Public Policy Center, Johns Hopkins University, Washington, DC 20036, USA. dkaufma2@jhu.edu
authors.forename: David J
authors.initials: DJ
authors.lastname: Kaufman
authors.forename: Juli
authors.initials: J
authors.lastname: Murphy-Bollinger
authors.forename: Joan
authors.initials: J
authors.lastname: Scott
authors.forename: Kathy L
authors.initials: KL
authors.lastname: Hudson
mesh_terms: D000293:Adolescent; D000328:Adult; D018070:Biological Specimen Banks / Q000941:ethics*; D035843:Biomedical Research / Q000941:ethics*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007258:Informed Consent / Q000941:ethics; D008297:Male; D008875:Middle Aged; D018907:Privacy; D011446:Prospective Studies; D011639:Public Opinion; D055815:Young Adult