Penumbra, the basis of neuroimaging in acute stroke treatment: current evidence.
In modern medicine brain imaging is an essential prerequisite not only to acute stroke triage but also to determining the specific therapy indicated. This article reviews the need for imaging the brain in acute stroke, penumbral pathophysiology, penumbral imaging techniques, as well as current status of various imaging modalities that are being employed to select patients for specific therapeutic approaches.
Kumar
Gyanendra
G
Department of Neurology, University of Missouri-Healthcare Columbia, Columbia, CE 507 Five Hospital Drive, Columbia, Missouri 65212, USA. kumargy@health.missouri.edu
Goyal
Munish Kumar
MK
Sahota
Pradeep Kumar
PK
Jain
Rajan
R
D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed