title: Preview. Inhibition of Tgf-beta signaling improves mouse fibroblast reprogramming.
abstract: Circumventing genomic modification in induced pluripotent stem cell (iPSC) derivation is a clear requirement to realize safe clinical applications. In this issue of Cell Stem Cell, Ichida et al., (2009) describe a small molecule capable of replacing Sox2, offering insight into the reprogramming process.
authors.affiliation: Ontario Human Induced Pluripotent Stem Cell Facility, Toronto, Canada. woltjen@lunenfeld.ca
authors.forename: Knut
authors.initials: K
authors.lastname: Woltjen
authors.forename: William L
authors.initials: WL
authors.lastname: Stanford