title: Pelvic lymphadenectomy in endometrial cancer: our current experience.
abstract: OBJECTIVE
  Lymph node involvement is the single most important factor in the prognosis of endometrial cancer, because it is predictive of locoregional and distant metastases. The purpose of our study was to determine whether lymphadenectomy is useful in the surgical staging of endometrial cancer and if it may help establish a more accurate prognosis and reduce the need for postoperative therapy in patients without surgical complications.
  
  
  METHODS
  We conducted a retrospective study on 55 patients with diagnosis of endometrial cancer.
  
  
  RESULTS
  Surgical staging of patients undergoing pelvic lymphadenectomy (47/55) showed that 59.6% of cases (n = 28) had Stage I cancer (IA in 4, IB in 16, IC in 8), 17.02% (n = 8) Stage II (IIA in 3, IIB in 5), 21.2% (n = 10) Stage III (IIIB in 5, IIIC in 5), and 2.1% (n = 1) Stage IVA. In the remaining eight patients with a very high anesthesiologic risk (ASA 4), surgical staging was incomplete because they underwent only node palpation.
  
  
  CONCLUSIONS
  In conclusion, as we wait for the sentinel lymph node technique to demonstrate satisfactory results and be standardized also for endometrial cancer, we believe that surgical lymph node dissection plays a crucial role in debulking this type of cancer. When performed by a good surgical oncology team, it does not entail a significantly increased operative risk.
authors.affiliation: Department of Gynecology, Obstetrics and Neonatology, University of Parma, Italy. titopatrelli@hotmail.com
authors.forename: T S
authors.initials: TS
authors.lastname: Patrelli
authors.forename: R
authors.initials: R
authors.lastname: Berretta
authors.forename: M
authors.initials: M
authors.lastname: Rolla
authors.forename: F
authors.initials: F
authors.lastname: Vandi
authors.forename: G
authors.initials: G
authors.lastname: Capobianco
authors.forename: D
authors.initials: D
authors.lastname: Gramellini
authors.forename: A
authors.initials: A
authors.lastname: Bacchi Modena
authors.forename: G B
authors.initials: GB
authors.lastname: Nardelli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D009367:Neoplasm Staging; D010388:Pelvis / Q000601:surgery; D012189:Retrospective Studies