Aryl hydrazide beyond as surrogate of aryl hydrazine in the Fischer indolization: the synthesis of N-Cbz-indoles, N-Cbz-carbazoles, and N,N'-bis-Cbz-pyrrolo[2,3-f]indoles.
Aryl hydrazides underwent the Fischer indolization reactions, while the N-carbamate group(s) remained intact to directly provide N-Cbz-indoles. This new method allowed the synthesis of various N-Cbz-carbazoles and N,N'-bis-Cbz-pyrrolo[2,3-f]indoles.
Park
In-Keol
IK
Department of Chemistry, Hanyang University, Seoul 133-791, Korea.
Suh
Sung-Eun
SE
Lim
Byeong-Yun
BY
Cho
Cheon-Gyu
CG
D002219:Carbamates / Q000737:chemistry; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
D002219:Carbamates; D002227:Carbazoles; D006834:Hydrazines; D007211:Indoles; D011758:Pyrroles