[Familial predisposition to stroke].
Fifty-five patients with ischemic stroke, 22 women, 33 men, mean age 61.14 +/- 11.8 years, have been interviewed. A control group included siblings of patients' spouses. In the group of relatives, the frequency of arterial hypertension was higher by 30.8%, diabetes mellitus--by 76%, ischemic heart disease--by 59.4% and stroke--by 41% compared to the controls. In the combined group, the relative risk (RR) of factors studied was substantially higher for relatives by blood. When effect of sex on RR has been determined, the higher RR values for all risk factors in male relatives of patients have been found. In conclusion, the study of familial predisposition to stroke revealed that family members of patients with stroke are a target group for stroke prevention programs.
Chinybaeva
L A
LA
Karazhanova
L K
LK
Kapakova
M A
MA
D000328:Adult; D017677:Age Distribution; D000368:Aged; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D020521:Stroke / Q000453:epidemiology / Q000235:genetics*