Estimating the contribution of genes to variation in renal drug clearance by active secretion using multiple data from clinical phase I studies.
Fujita
Tomoe
T
Department of Pharmacology, Kitasato University School of Medicine, Kitasato 1-15-1, Sagamihara, Kanagawa 228-8555. fujita-t@kitasato-u.ac.jp
Kumagai
Yuji
Y
Nakahara
Ichimi
I
Ohtani
Yoshio
Y
Majima
Masataka
M
D017321:Clinical Trials, Phase I as Topic; D005796:Genes; D005919:Glomerular Filtration Rate / Q000235:genetics; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D008657:Metabolic Clearance Rate / Q000235:genetics*; D004364:Pharmaceutical Preparations; D010599:Pharmacokinetics
D004364:Pharmaceutical Preparations