The effect of 50 hz magnetic field of different shape on oxygen metabolism in blood platelets: in vitro studies.
OBJECTIVE
The aim of the study was to assess the influence that the shape of low frequency magnetic field may have on catalase and superoxide dismutase activity, malondialdehyde concentration and free radicals generation in human blood platelets.


METHODS
The suspension of human blood platelets was exposed for 15 min to 50 Hz magnetic field of different shape, and flux density of 10 mT.


RESULTS
The determinations of free radicals, malondialdehyde and catalase showed increased values compared with the initial level, regardless of the shape of the magnetic field applied. In contrast, superoxide dismutase activity was lower than at the onset of the experiment.


CONCLUSIONS
The findings indicate that the oxidative stress resulting from exposure to 50 Hz magnetic field of 10 mT induction may produce a number of adverse effects within the cell and thus may lead to systemic disturbances in the human body.
Henrykowska
Gabriela
G
Health Education and Promotion Department, Medical University of Łódź, Łódź, Poland. gabriela.henrykowska@umed.lodz.pl
Jankowski
Wojciech
W
Pacholski
Krzysztof
K
Lewicka
Małgorzata
M
Smigielski
Janusz
J
Dziedziczak-Buczyńska
Maria
M
Buczyński
Andrzej
A
D001792:Blood Platelets / Q000378:metabolism / Q000528:radiation effects*; D002374:Catalase / Q000378:metabolism; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D008315:Malondialdehyde / Q000378:metabolism; D010100:Oxygen / Q000097:blood*; D013482:Superoxide Dismutase / Q000378:metabolism
D005609:Free Radicals; D008315:Malondialdehyde; D002374:Catalase; D013482:Superoxide Dismutase; D010100:Oxygen