title: Friction of F-actin knots.
abstract: We use the existing data of force-extension experiments on F-actin molecules tied into knots to compute a value of 0.15 for the static friction coefficient for contact between different parts of the same molecule with itself. This estimate for protein-protein friction is relevant for the stabilization of the 273 known proteins with knots, one percent of the structures deposited in the Protein Data Bank.
authors.affiliation: INM-Leibniz Institute for New Materials, Saarbrücken, Germany.
authors.forename: Helmut O
authors.initials: HO
authors.lastname: Kirchner
authors.forename: Sebastien
authors.initials: S
authors.lastname: Neukirch
mesh_terms: D000199:Actins / Q000737:chemistry*; D003198:Computer Simulation; D030562:Databases, Protein; D017276:Friction
chemical_list: D000199:Actins