Alternative routes of insulin delivery.
Parenteral route of insulin administration has been the mode of treatment for all Type 1 diabetics and Type 2 diabetics with complications. Patient compliance has really been a major concern for this route of administration. Several alternative routes of administration are under consideration for effective glycemic control, including oral, inhaled, buccal, nasal, and patch routes. One of the approaches involving inhaled insulin has now reached the market. Several other candidates may reach the market in the near future, the promising one being oral insulin.
Krishnankutty
Ranjith K
RK
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Mathew
Aju
A
Sedimbi
Saikiran K
SK
Suryanarayan
Shrikumar
S
Sanjeevi
Carani B
CB
D000278:Administration, Buccal; D000280:Administration, Inhalation; D000281:Administration, Intranasal; D000284:Administration, Oral; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004333:Drug Administration Routes; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*
D007004:Hypoglycemic Agents; D007328:Insulin