title: Late cutaneous metastases to the face from malignant pleural mesothelioma: a case report and review of the literature.
abstract: BACKGROUND
  Malignant Mesothelioma is a rare primary neoplasm affecting the serosal membranes. During its relative short course, this malignant neoplasm can give local and, rarely, distant haematogenous metastases in different organs. The reported metastatic sites include liver, lung, heart, brain, thyroid, adrenals, kidneys, pancreas, bone, soft tissue, skin and lymph nodes.
  
  
  METHODS
  We report a sixty one year-old man with a history of malignant pleural epithelioid mesothelioma treated with six cycles of Pemetrexed and Carboplatin completed 03/11/04 followed by radiotherapy to the drain site 250 Kv/TD20Gy/5F completed 13/12/2004. Then he developed multiple facial skin lesions 4 years later. These lesions were proved to be metastatic malignant sarcomatoid mesothelioma.
  
  
  CONCLUSIONS
  Mesothelioma metastases should be suspected in any known Mesothelioma patient with newly developed skin lesion.
authors.affiliation: Clinical Oncology Department, Mid Essex Hospital Services NHS Trust, Broomfield Hospital, Court Road, Chelmsford, CM1 7ET, UK. aelbahaie@nhs.net
authors.forename: Alaaeldeen M
authors.initials: AM
authors.lastname: Elbahaie
authors.forename: Dia E
authors.initials: DE
authors.lastname: Kamel
authors.forename: Julia
authors.initials: J
authors.lastname: Lawrence
authors.forename: Neville G
authors.initials: NG
authors.lastname: Davidson
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000556:secondary* / Q000628:therapy; D005971:Glutamates / Q000627:therapeutic use; D006147:Guanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D000068437:Pemetrexed; D010997:Pleural Neoplasms / Q000473:pathology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000556:secondary* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine; D016190:Carboplatin