title: MAXIMA IN RATE-CONCENTRATION CURVES AND THEIR RELATION TO THE STRUCTURAL ASPECTS OF CELLULAR METABOLISM.
abstract: 1. Reproducible maxima are exhibited in the rate-concentration curves obtained by studying the effects of ethyl- and phenylurethanes on regeneration rates of hydranths in Tubularia. 2. The general problem of maxima in rate-concentration curves is analyzed in terms of reaction kinetics of relatively simple systems. 3. Certain systems were shown to exhibit this phenomenon. A comparison is made of these with similar ones which fail to do so. 4. The possible rôle in this phenomenon of cellular structure and its attendant geometrical constraints is discussed in terms of the above comparison.
authors.affiliation: Department of Bacteriology and Immunology, Washington University School of Medicine, St. Louis, Missouri, Department of Physiology, University of Minnesota, Minneapolis, Minnesota, and the Marine Biological Laboratory, Woods Hole, Massachusetts.
authors.forename: S
authors.initials: S
authors.lastname: Spiegelman
authors.forename: J M
authors.initials: JM
authors.lastname: Reiner