title: Resistance of turkeys to experimental infection with an early 2009 Italian human influenza A(H1N1)v virus isolate.
abstract: We performed an experimental infection of 21- and 70-day-old meat turkeys with an early human isolate of the 2009 pandemic H1N1 influenza virus exhibiting an alpha-2,3 receptor binding profile. Virus was not recovered by molecular or conventional methods from blood, tracheal and cloacal swabs, lungs, intestine or muscle tissue. Seroconversion was detected in a limited number of birds with the homologous antigen only. Our findings suggest that in its present form, the pandemic H1N1 influenza virus is not likely to be transmitted to meat turkeys and does therefore not represent an animal health or food safety issue for this species.
authors.affiliation: OIE/FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating centre for infectious diseases at the human-animal interface, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Legnaro, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Terregino
authors.forename: R
authors.initials: R
authors.lastname: De Nardi
authors.forename: R
authors.initials: R
authors.lastname: Nisi
authors.forename: F
authors.initials: F
authors.lastname: Cilloni
authors.forename: A
authors.initials: A
authors.lastname: Salviato
authors.forename: M
authors.initials: M
authors.lastname: Fasolato
authors.forename: I
authors.initials: I
authors.lastname: Capua
mesh_terms: D000818:Animals; D004198:Disease Susceptibility; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D005585:Influenza in Birds / Q000276:immunology*; D007558:Italy; D014422:Turkeys / Q000276:immunology*