title: Effect of age on changes in anterior chamber depth and volume after laser in situ keratomileusis.
abstract: OBJECTIVE
  To evaluate the effect of age on anterior chamber depth (ACD) and anterior chamber volume (ACV) after laser in situ keratomileusis (LASIK) for myopia.
  
  
  METHODS
  Department of Ophthalmology, Keio University School of Medicine, and a private clinic, Tokyo, Japan.
  
  
  METHODS
  In this retrospective study, patients who had uneventful LASIK for myopia or myopic astigmatism were divided into 2 groups: younger (younger than 40 years) and older (40 years and older). Central corneal thickness, central corneal true net power, ACV, and central ACD were measured using a rotating Scheimpflug camera preoperatively and 1 month postoperatively. These parameters were compared between the 2 groups.
  
  
  RESULTS
  The study evaluated 161 eyes of 83 patients (mean age 34.5 years +/- 8.3 [SD]). The decreases in central ACD and ACV after LASIK were statistically significant in the younger group (P<.0001 and P = .0050, respectively) but not in the older group.
  
  
  CONCLUSIONS
  Central ACD and the ACV decreased significantly after LASIK in younger patients (<40 years) but not in older patients, indicating that age influences changes in ACD and ACV after LASIK.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Nishimura
authors.forename: Kazuno
authors.initials: K
authors.lastname: Negishi
authors.forename: Murat
authors.initials: M
authors.lastname: Dogru
authors.forename: Megumi
authors.initials: M
authors.lastname: Saiki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Arai
authors.forename: Ikuko
authors.initials: I
authors.lastname: Toda
authors.forename: Takefumi
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology*; D000867:Anterior Chamber / Q000473:pathology*; D001251:Astigmatism / Q000601:surgery; D003315:Cornea / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery; D011184:Postoperative Period; D057234:Preoperative Period; D012189:Retrospective Studies; D055815:Young Adult