Effect of anti retroviral therapy (ART) on CD4 T lymphocyte count and the spectrum of opportunistic infections in HIV/AIDS in Manipur.
Reports of variable response to antiretroviral therapy as indicated by CD4 count has been of concern as facilities for viral load estimation/drug resistance testing is not available everywhere. Hence the present study. was done to assess the magnitude of problem in high prevalence state of Manipur as evidenced by the CD4 T lymphocyte count. It was also prudent to study various OIs as extensive awareness campaigns about HIV and related morbidity with support system has been undertaken since the last decade. The study revealed that HAART must be used judiciously as 17.3% showed no improvement in CD4 T lymphocyte count. Among opportunistic infections, fungal infections predominatd in HIV/AIDS.
Chitra
Yengkokpam
Y
Department of Microbiology, Regional Institute of Medical Sciences, Manipur. chandi_yengkokpam@yahoo.com
Urgen
Sherpa
S
Dayananda
Ingudam
I
Brajachand
Singh Ng
SN
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000188:drug therapy* / Q000276:immunology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001424:Bacterial Infections / Q000150:complications / Q000453:epidemiology / Q000276:immunology; D018791:CD4 Lymphocyte Count; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000453:epidemiology / Q000276:immunology; D010272:Parasitic Diseases / Q000150:complications / Q000453:epidemiology / Q000276:immunology