title: Detection of traumatic cerebral microbleeds by susceptibility-weighted image of MRI.
abstract: OBJECTIVE
  Susceptibility-weighted image (SWI) is a sensitive magnetic resonance image (MRI) technique to detect cerebral microbleeds (MBLs), which would not be detected by conventional MRI. We performed SWI to detect MBLs and investigated its usefulness in the evaluation of mild traumatic brain injury (MTBI) patients.
  
  
  METHODS
  From December 2006 to June 2007, twenty-one MTBI patients without any parenchymal hemorrhage on conventional MRI were selected. Forty-two patients without trauma were selected for control group. According to the presence of MBLs, we divided the MTBI group into MBLs positive [SWI (+)] and negative [SWI (-)] group. Regional distribution of MBLs and clinical factors were compared between groups.
  
  
  RESULTS
  Fifty-one MBLs appeared in 16 patients of SWI (+) group and 16 MBLs in 10 patients of control group [control (+)], respectively. In SWI (+) group, MBLs were located more frequently in white matters than in deep nucleus different from the control (+) group (p < 0.05). Nine patients (56.3%) of SWI (+) group had various neurological deficits (disorientation in 4, visual field defect in 2, hearing difficulty in 2 and Parkinson syndrome in 1). Initial Glasgow Coma Scale (GCS)/mean Glasgow Outcome Scale (GOS) were 13.9 +/- 1.5 / 4.7 +/- 0.8 and 15.0 +/- 0.0 / 5.0 +/- 0.0 in SWI (+) and SWI (-) groups, respectively (p < 0.05).
  
  
  CONCLUSIONS
  Traumatic cerebral MBLs showed characteristic regional distribution, and seemed to have an importance on the initial neurological status and the prognosis. SWI is useful for detection of traumatic cerebral MBLs, and can provide etiologic evidences for some post-traumatic neurologic deficits which were unexplainable with conventional MRI.
authors.affiliation: Department of Neurosurgery, College of Medicine, Chung-Ang University, Yongsan Hospital, Seoul, Korea.
authors.forename: Jong-Hwa
authors.initials: JH
authors.lastname: Park
authors.forename: Seung-Won
authors.initials: SW
authors.lastname: Park
authors.forename: Suk-Hyung
authors.initials: SH
authors.lastname: Kang
authors.forename: Taek-Kyun
authors.initials: TK
authors.lastname: Nam
authors.forename: Byung-Kook
authors.initials: BK
authors.lastname: Min
authors.forename: Sung-Nam
authors.initials: SN
authors.lastname: Hwang