title: Omega-3 polyunsaturated Fatty Acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation.
abstract: OBJECTIVE
  To assess if patients treated with omega-3(n-3) polyunsaturated fatty acids (PUFAS) had lower procedural failure rates compared to an untreated population.
  
  
  RESULTS
  From January 2004 to 2007, 1500 PVAI patients underwent catheter ablation. Two hundred and eighty five (19%) patients were treated with PUFAs. These patients were matched in a nested case controlled analysis. After matching, there were 129 patients in the PUFA group and 129 in the control group. Thirty-five (27.1%) patients in the study group had early recurrence vs. 57 (44.1%) in the control group p-value< 0.0001. Twenty-nine (23.2%) patients in the PUFA group vs. 41 (31.7%) in the non-PUFA group had procedural failure (p-value < 0.003). There were no significant differences in complications in the PUFA and non-PUFA groups.
  
  
  CONCLUSIONS
  Patients treated with PUFAs had lower incidences of early recurrence and procedural failure compared to an untreated population.
authors.affiliation: Texas Cardiac Arrhythmia, St. David's Medical Center, Austin, Texas, USA. dimpi.patel.afib@gmail.com
authors.forename: Dimpi
authors.initials: D
authors.lastname: Patel
authors.forename: Mazen
authors.initials: M
authors.lastname: Shaheen
authors.forename: Preeti
authors.initials: P
authors.lastname: Venkatraman
authors.forename: Luciana
authors.initials: L
authors.lastname: Armaganijan
authors.forename: Javier E
authors.initials: JE
authors.lastname: Sanchez
authors.forename: Rodney P
authors.initials: RP
authors.lastname: Horton
authors.forename: Luigi
authors.initials: L
authors.lastname: Di Biase
authors.forename: Prasant
authors.initials: P
authors.lastname: Mohanty
authors.forename: Robert
authors.initials: R
authors.lastname: Canby
authors.forename: Shane M
authors.initials: SM
authors.lastname: Bailey
authors.forename: J David
authors.initials: JD
authors.lastname: Burkhardt
authors.forename: G Joseph
authors.initials: GJ
authors.lastname: Gallinghouse
authors.forename: Jason D
authors.initials: JD
authors.lastname: Zagrodzky
authors.forename: Marketa
authors.initials: M
authors.lastname: Kozeluhova
authors.forename: Andrea
authors.initials: A
authors.lastname: Natale