title: [Vacuum sealing drainage for infection wound in earthquake].
abstract: OBJECTIVE
  To investigate the effect of vacuum sealing drainage (VSD) technology on prevention and treatment of infection wound and to repair the infectious fracture wound in earthquake.
  
  
  METHODS
  Twenty-two patients with limb fractures and open infection wound received VSD from May 12, 2008 to June 19, 2008 in West China Hospital of Sichuan University. Before the VSD, we debrided all wounds and gave effective systemic antibiotics. A -18 ~ -14 kPa pressure was exerted to the wound, and the VSD was used for 8-10 days. We took a germiculture regularly. The capacity, color, and nature of negative pressure drainage, the regression of limb swelling, and systemic inflammatory responses were observed.
  
  
  RESULTS
  There was no active bleeding wound or transparent film off in all patients. Three patients had drainage clogging, and were kept flowing freely using the sterile saline pipe to remove the blockage of necrotic tissues. During the VSD, granulation tissues grew well in the 13 patients with bone exposure of the wounded. Two patients whose symptom of inflammatory was not obviously eased had another debridement to completely remove the necrosis, and the symptom was relieved. After 3-5 days of VSD, swelling and fever in the other 20 patients significantly subsided.
  
  
  CONCLUSIONS
  VSD can alleviate the wound inflammation, facilitate the growth of the fresh granulation tissue from the surrounding to the center, and reduce the flap transfer area for the Stage II coverage of the exposed bone.
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Dengbin
authors.initials: D
authors.lastname: Liao
authors.forename: Ning
authors.initials: N
authors.lastname: Ning
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Liu
authors.forename: Chunlan
authors.initials: C
authors.lastname: Gan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004190:Disasters; D055866:Earthquakes; D005260:Female; D050723:Fractures, Bone / Q000601:surgery*; D005597:Fractures, Open / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D013396:Suction / Q000379:methods; D014618:Vacuum; D014946:Wound Infection / Q000601:surgery*; D055815:Young Adult