Controlling myocyte cGMP: phosphodiesterase 1 joins the fray.
Takimoto
Eiki
E
D000804:Angiotensin II / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling / Q000187:drug effects / Q000528:radiation effects*; D002147:Calmodulin / Q000378:metabolism*; D006332:Cardiomegaly / Q000139:chemically induced / Q000201:enzymology*; D002316:Cardiotonic Agents / Q000009:adverse effects / Q000494:pharmacology; D002478:Cells, Cultured; D006152:Cyclic GMP / Q000378:metabolism*; D054677:Cyclic Nucleotide Phosphodiesterases, Type 1 / Q000096:biosynthesis*; D004791:Enzyme Inhibitors / Q000009:adverse effects / Q000494:pharmacology; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects / Q000502:physiology; D006352:Heart Ventricles / Q000201:enzymology; D006801:Humans; D007545:Isoproterenol / Q000009:adverse effects / Q000494:pharmacology; D008297:Male; D051379:Mice; D032383:Myocytes, Cardiac / Q000201:enzymology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015290:Second Messenger Systems / Q000187:drug effects / Q000502:physiology*
D002147:Calmodulin; D002316:Cardiotonic Agents; D004791:Enzyme Inhibitors; D000804:Angiotensin II; D054677:Cyclic Nucleotide Phosphodiesterases, Type 1; C527988:Pde1A protein, mouse; C517263:Pde1a protein, rat; D006152:Cyclic GMP; D007545:Isoproterenol; D002118:Calcium