title: Prevalence, incidence, morbidity and treatment patterns in a cohort of patients diagnosed with anxiety in UK primary care.
abstract: BACKGROUND
  Anxiety disorders are common and can cause substantial quality of life impairment.
  
  
  OBJECTIVE
  The aim of this study was to investigate the frequency of anxiety in UK primary care. Treatment patterns and factors associated with an anxiety diagnosis were also assessed.
  
  
  METHODS
  The Health Improvement Network was used to identify all patients aged 10-79 years with a new diagnosis of anxiety in 2002-04 (n = 40 873) and age-, sex- and calendar-year-matched controls (n = 50 000). A nested case-control analysis was used to quantify potential risk factors for anxiety by multivariate logistic regression.
  
  
  RESULTS
  The prevalence of anxiety was 7.2% and the incidence was 9.7 per 1000 person-years. Incidence and prevalence were highest in women and young adults (20-29 years). Anxiety was associated with heavy alcohol use, smoking and addiction problems as well as stress, sleep and depression disorders. Anxiety patients used health care services more frequently than controls. Among patients diagnosed with anxiety, 63% were treated pharmacologically. Antidepressants accounted for almost 80% of prescriptions.
  
  
  CONCLUSIONS
  The prevalence and incidence of anxiety are high in UK primary care and are almost twice as high in women than in men. Anxiety is associated with other psychiatric morbidity as well as frequent health care use. Antidepressants are the most commonly used pharmacological treatment.
authors.affiliation: Centro Español de Investigación Farmacoepidemiológica, Almirante 28 (no. 2), Madrid, Spain. elisaceife@telefonica.net
authors.forename: Elisa
authors.initials: E
authors.lastname: Martín-Merino
authors.forename: Ana
authors.initials: A
authors.lastname: Ruigómez
authors.forename: Mari-Ann
authors.initials: MA
authors.lastname: Wallander
authors.forename: Saga
authors.initials: S
authors.lastname: Johansson
authors.forename: Luis Alberto
authors.initials: LA
authors.lastname: García-Rodríguez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D002648:Child; D015331:Cohort Studies; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011320:Primary Health Care; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult