title: MAP-ping unconventional protein-DNA interactions.
abstract: Control of gene expression depends on a myriad of protein-DNA interactions, and the number of proteins involved just got larger. In this issue, Hu et al. (2009) identify hundreds of human proteins that bind to DNA, including many surprises such as the protein kinase ERK2 (MAPK1) that now appears to control gene expression directly.
authors.affiliation: Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.
authors.forename: Elhadji M
authors.initials: EM
authors.lastname: Dioum
authors.forename: Eric M
authors.initials: EM
authors.lastname: Wauson
authors.forename: Melanie H
authors.initials: MH
authors.lastname: Cobb
mesh_terms: D004247:DNA / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005786:Gene Expression Regulation; D006801:Humans; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; D004247:DNA; D019950:Mitogen-Activated Protein Kinase 1