title: Fibromatosis in a young Bernese Mountain Dog: clinical, imaging, and histopathological findings.
abstract: A young, intact, male Bernese Mountain Dog was presented to the animal hospital for lameness and diffuse thickening of the soft tissue in the right hind limb. Magnetic resonance imaging revealed multiple, multilobular, space-occupying lesions within and between the muscles of the right femur. Biopsies taken from the lesions revealed an infiltrative mass composed mainly of collagen fibers and a low density of benign-appearing fibroblasts. These findings were compatible with a diagnosis of a fibromatosis. Taking the age of onset into account, infantile fibromatosis was most likely. A deep fibromatosis, similar to that seen in adults, could not be excluded based on histology.
authors.affiliation: Institute of Animal Pathology, Vetsuisse Faculty, University of Berne, Bern, Switzerland. monika.welle@itpa.unibe.ch
authors.forename: Monika M
authors.initials: MM
authors.lastname: Welle
authors.forename: Esther
authors.initials: E
authors.lastname: Sutter
authors.forename: Yasminda
authors.initials: Y
authors.lastname: Malik
authors.forename: Martin
authors.initials: M
authors.lastname: Konar
authors.forename: Silvia
authors.initials: S
authors.lastname: Rüfenacht
authors.forename: Judith E K
authors.initials: JE
authors.lastname: Howard
mesh_terms: D000818:Animals; D001706:Biopsy; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D004285:Dogs; D005350:Fibroma / Q000473:pathology / Q000662:veterinary*; D006614:Hindlimb / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D014746:Vimentin / Q000032:analysis
chemical_list: D014746:Vimentin