title: Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.
abstract: Base-mediated double conjugate addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for an efficient and scalable synthesis of beta-carbonyl silyl-1,3-dithianes.
authors.affiliation: Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA.
authors.forename: Sumit
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Dimitra
authors.initials: D
authors.lastname: Kontokosta
authors.forename: Aditi
authors.initials: A
authors.lastname: Patil
authors.forename: Sivakumar
authors.initials: S
authors.lastname: Rallapalli
authors.forename: Daesung
authors.initials: D
authors.lastname: Lee
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008722:Methods; D011807:Quinolizines / Q000138:chemical synthesis*; D012821:Silanes; D013457:Sulfur Compounds / Q000138:chemical synthesis*; D014050:Toluene / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D000447:Aldehydes; D000480:Alkynes; D007659:Ketones; D011807:Quinolizines; D012821:Silanes; D013457:Sulfur Compounds; C438055:dithiane; D014050:Toluene; C004848:dithiol