[Steroids from Monascus purpureus metabolite].
OBJECTIVE
To study the chemical constituents of Monascus purpureus metabolite.


METHODS
The compounds were isolated by column chromatography methods, and their structures were determined by spectroscopic methods.


RESULTS
Eight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one (1), 3-oxo-24-methylenecycloarane (2), stigmasterol (3), 7beta-hydroxystigmasterol (4), 3beta-hydroxystigmast-5-en-7-one (5), 3beta-hydroxystigmast-5,22-dien-7-one (6), 5alpha, 8alpha-epidioxyergosta-6,22-dien-3beta-ol (7), sitosterol (8).


CONCLUSIONS
All of the compounds were isolated from this genu for the first time except compound 3 and 7.
Shang
Xiaoya
X
Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100083, China. shangxiaoya@tgi.edu.cn
Wang
Ruolan
R
Yin
Suqin
S
Li
Jinjie
J
Jin
Zonglian
Z
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D032741:Monascus / Q000737:chemistry* / Q000378:metabolism*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*
D004365:Drugs, Chinese Herbal; D013256:Steroids