title: Two modes of autoregulation of the murR repressor in Escherichia coli.
abstract: The murPQ operon of Escherichia coli encoding the enzymes for degradation of MurNAc is derepressed by MurR (YfeT) in the presence of MurNAc-6-phosphate. MurR also represses its own expression. We found that murR is stimulated in rich medium. This activation involves MurR and most of the IIBC components of the phosphotransferase system, suggesting auto-induction of murR by an activated form of MurR.
authors.affiliation: Department of Frontier Bioscience, Hosei University, Tokyo, Japan.
authors.forename: Daiki
authors.initials: D
authors.lastname: Ishii
authors.forename: Akira
authors.initials: A
authors.lastname: Ishihama
authors.forename: Kaneyoshi
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics* / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D009876:Operon / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics* / Q000378:metabolism*; D015533:Transcriptional Activation
chemical_list: D029968:Escherichia coli Proteins; C547205:MurR protein, E coli; D012097:Repressor Proteins