Short-step synthesis of a resveratrol derivative from commercially available 1,3-dimethoxybenzene and 4-vinylanisole.
An efficient synthesis of tri-O-methylated resveratrol is presented using an advanced Heck reaction promoted by Pd(dba)(2) in the presence of P(t-Bu)(3).
Iijima
Takashi
T
Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University, Kami-ina, Nagano, Japan.
Makabe
Hidefumi
H
D000840:Anisoles / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry; D000077185:Resveratrol; D013237:Stereoisomerism; D013267:Stilbenes / Q000138:chemical synthesis* / Q000737:chemistry; D013343:Styrenes / Q000737:chemistry*
D000840:Anisoles; D013267:Stilbenes; D013343:Styrenes; C031201:1,3-dimethoxybenzene; C534356:4-methoxystyrene; D007495:Iridium; D000077185:Resveratrol