title: A methodology to study the effects of prosthesis misfit over time: an in vivo model.
abstract: OBJECTIVE
  Passive fit of implant-supported superstructures cannot currently be achieved. The aim of this investigation was to create a methodology that can be used to study the effects of prosthesis misfit in humans.
  
  
  METHODS
  An edentulous patient received two interforaminal implants and a screw-retained bar for the retention of the mandibular denture. A corresponding in vitro model with strain gauges placed mesially and distally, adjacent to the implants, was fabricated to serve as a standardizing control. Over a period of 6 months, a total of 10 measurements on both the in vitro model and in the patient's mouth were conducted with newly fixed strain gauges on the bar.
  
  
  RESULTS
  The in vitro experiments showed that no component wear at the abutment-bar interface had occurred and that repositioning of the strain gauges on the bar caused deviations in strain measurements up to 10.55%. In vivo, a reduction in strain development, from 445 to 383 Mum/m, was observed in the initial phase up to 12 weeks after bar insertion. Subsequently, the measurement values increased, and after a period of 24 weeks, they nearly reached the initial strain level (443 microm/m). Only minor changes in strain development of the bar could be detected; these might be a result of limited dynamic loading and the cortical architecture of the surrounding bone. Deviations in measurement accuracy caused by repositioning of the bar strain gauge are a limitation of this technique and should be eliminated in future studies.
  
  
  CONCLUSIONS
  The present methodology can be applied to study changes in static implant loading over time in humans.
authors.affiliation: Department of Prosthodontics, School of Dental Medicine, University of Erlangen-Nuremberg, Erlangen, Germany. karl_matthias@web.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Karl
authors.forename: Friedrich
authors.initials: F
authors.lastname: Graef
authors.forename: Siegfried
authors.initials: S
authors.lastname: Heckmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Taylor
mesh_terms: D001696:Biomechanical Phenomena; D000044:Dental Abutments / Q000592:standards / Q000706:statistics & numerical data; D015921:Dental Implants / Q000592:standards / Q000706:statistics & numerical data; D018772:Dental Marginal Adaptation / Q000592:standards*; D019094:Dental Prosthesis, Implant-Supported / Q000592:standards / Q000706:statistics & numerical data; D019554:Dental Restoration Wear; D003779:Denture Design / Q000592:standards / Q000706:statistics & numerical data; D003781:Denture Retention / Q000592:standards / Q000706:statistics & numerical data; D003826:Denture, Complete, Lower; D003828:Denture, Overlay; D006801:Humans; D007575:Jaw, Edentulous / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery; D008334:Mandible / Q000503:physiopathology / Q000601:surgery; D008422:Materials Testing; D008875:Middle Aged; D008953:Models, Anatomic; D013314:Stress, Mechanical; D019415:Torque; D014159:Transducers
chemical_list: D015921:Dental Implants