18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging findings of primary intracranial histiocytic sarcoma in a dog.
A 10-year-old, neutered male, Maltese dog presented with a three week history of intention tremor, right hind limb rigidity, poor coordination, and occasional circling to the left. On magnetic resonance imaging (MRI) of the brain, a mass was identified in the right occipital lobe and cerebellum. Three weeks after the initial MRI scan, we performed an (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) of the brain. The FDG-PET demonstrated areas of hypermetabolism in the right occipital lobe, cerebellum, pons, and medulla oblongata. When the standardized uptake value was calculated, the hypermetabolic lesion was higher than the gray matter values. The anatomical location of the hypermetabolic lesion was more precisely identified by the PET-MRI fusion images. The dog was definitively diagnosed as a primary histiocytic sarcoma of the brain. This is the first report of PET findings of an intracranial histiocytic sarcoma in a dog.
Kang
Byeong-Teck
BT
BK21 Program of Basic and Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwang-jin-gu, Seoul.
Park
Chul
C
Yoo
Jong-Hyun
JH
Gu
Su-Hyun
SH
Jang
Dong-Pyo
DP
Kim
Young-Bo
YB
Woo
Eung-Je
EJ
Kim
Dae-Young
DY
Cho
Zang-Hee
ZH
Park
Hee-Myung
HM
D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D019788:Fluorodeoxyglucose F18; D054747:Histiocytic Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D049268:Positron-Emission Tomography / Q000662:veterinary*
D019788:Fluorodeoxyglucose F18