title: Jatrophalactam, a novel diterpenoid lactam isolated from Jatropha curcas.
abstract: Jatrophalactam (1), a novel diterpenoid lactam possessing an unprecedented 5/13/3 tricyclic skeleton, was isolated from the roots of Jatropha curcas. The structure and relative configuration of jatrophalactam (1) were elucidated by extensive spectroscopic analysis and further determined by a single-crystal X-ray diffraction.
authors.affiliation: Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 199 Guo Shou Jing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
authors.forename: Xia-Chang
authors.initials: XC
authors.lastname: Wang
authors.forename: Zong-Ping
authors.initials: ZP
authors.lastname: Zheng
authors.forename: Xian-Wen
authors.initials: XW
authors.lastname: Gan
authors.forename: Li-Hong
authors.initials: LH
authors.lastname: Hu
mesh_terms: D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D031286:Jatropha / Q000737:chemistry*; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry
chemical_list: D004224:Diterpenes; D007769:Lactams