title: Family-focused cognitive behaviour therapy versus psycho-education for chronic fatigue syndrome in 11- to 18-year-olds: a randomized controlled treatment trial.
abstract: BACKGROUND
  Only one previous randomized controlled trial (RCT) has examined the efficacy of cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) in children. The aim of this study was to compare family-focused CBT with psycho-education for CFS in adolescents.
  
  
  METHODS
  Sixty-three 11- to 18-year-olds (43 girls, 20 boys) with CFS were randomly assigned to either family-focused CBT or psycho-education delivered over 6 months. School attendance was the main outcome, which was assessed at the end of treatment and at 3, 6 and 12 months follow-up.
  
  
  RESULTS
  At the main outcome point (the 6-month follow-up) both groups had improved similarly. However, although those who received family-focused CBT were attending school for longer than those who received psycho-education, at discharge from treatment and at 3 months follow-up, they improved less quickly across the follow-up period.
  
  
  CONCLUSIONS
  Adolescents with CFS get back to school more quickly after family-focused CBT. This is important as they are at a crucial stage of their development. However, the finding that psycho-education was as effective as family-focused CBT at 6 and 12 months follow-up has important implications for health service delivery.
authors.affiliation: Department of Psychological Medicine and Psychiatry, King's College London, Weston Education Centre, London, UK. trudie.chalder@kcl.ac.uk
authors.forename: T
authors.initials: T
authors.lastname: Chalder
authors.forename: V
authors.initials: V
authors.lastname: Deary
authors.forename: K
authors.initials: K
authors.lastname: Husain
authors.forename: R
authors.initials: R
authors.lastname: Walwyn
mesh_terms: D000041:Absenteeism; D000223:Adaptation, Psychological; D000293:Adolescent; D002648:Child; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005196:Family Therapy / Q000379:methods*; D015673:Fatigue Syndrome, Chronic / Q000523:psychology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010353:Patient Education as Topic / Q000379:methods*; D010552:Personality Assessment; D012803:Sick Role; D012917:Social Adjustment