[The treatment of fibrous dysplasia involving skull base].
OBJECTIVE
To investigate the diagnosis and treatment of fibrous dysplasia (FD) involving the skull base.


METHODS
The clinical data of 15 patients with fibrous dysplasia involving the skull base was retrospective analysis.


RESULTS
All patients were underwent CT examinations. FD involved orbital roof in 15 patients, ethmoidal bone in 15 patients, middle and lower nasal turbinate in 8 patients, frontal bone in 8 patients, sphenoidal bone in 6 patients, and maxillary bone in a patient. Although the optic canal was affected in 4 patients, only one patient had impaired vision. All the patients were treated by craniofacial approach. One patient with impaired vision was performed decompression of optic canal and had improved in vision. The titanium mesh was use for construction of skull base defect. There were not complications, such as infection, cerebral hemorrhage, etc.


CONCLUSIONS
It should be underwent surgical treatment for fibrous dysplasia involving skull base which resulted in clinical manifestations. Whether prophylactic decompression of optic canal is performed or notr depends on the patients clinical and radiological information.
Zhou
Weiguo
W
Key Laboratory of Otolaryngology-Head and Neck Surgery, Ministry of Education, Tongren Hospital, Capital Medical University, Beijing 100730, China. zhouweiguosky@sohu.com
Ni
Xin
X
Huang
Zhigang
Z
Fang
Jugao
J
Wang
Qi
Q
Chen
Xiaohong
X
Chen
Xuejun
X
Xu
Hongbo
H
D000293:Adolescent; D000328:Adult; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000473:pathology* / Q000601:surgery*; D005624:Frontal Bone / Q000473:pathology; D006801:Humans; D008297:Male; D008437:Maxilla / Q000473:pathology; D009915:Orbit / Q000601:surgery; D012189:Retrospective Studies; D019291:Skull Base / Q000473:pathology*; D013100:Sphenoid Bone / Q000473:pathology; D055815:Young Adult