MOUSE-PROTECTIVE TITERS OF SERA OF VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES.
1. Sera of human subjects immunized with pneumococci or their type-specific polysaccharides showed type-specific antibody by mouse protection tests as well as on determinations of the specifically precipitable nitrogen. 2. The ratio, mouse-protective units to antibody nitrogen, was less in human sera of low potency than in more potent human or animal sera.
Walter
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AW
Bureau of Laboratories of the Department of Health of the City of New York, New York.
Schenkein
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EL
Sutliff
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WD