title: Smiles rearrangement as a tool for the preparation of dihydrodipyridopyrazines.
abstract: A novel methodology for the synthesis of isomer A of dihydrodipyridopyrazines was developed. The key transformation features a Smiles rearrangement of nitro substituted N,N'-dipyridinylamines, potential precursors of isomer B obtained by the alkylation of compounds prepared by a Pd-catalyzed reaction and subsequent cyclization.
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans, UMR CNRS 6005, France.
authors.forename: Oana-Irina
authors.initials: OI
authors.lastname: Patriciu
authors.forename: Adriana-Luminita
authors.initials: AL
authors.lastname: Fînaru
authors.forename: Stéphane
authors.initials: S
authors.lastname: Massip
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Leger
authors.forename: Christian
authors.initials: C
authors.lastname: Jarry
authors.forename: Gérald
authors.initials: G
authors.lastname: Guillaumet
mesh_terms: D000478:Alkylation; D002384:Catalysis; D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011719:Pyrazines / Q000138:chemical synthesis* / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006575:Heterocyclic Compounds, 3-Ring; D011719:Pyrazines; D011725:Pyridines