Juvenile xanthogranuloma with bilateral ocular involvement: complete response after treatment with vinblastine: case report.
OBJECTIVE
To present an infant with bilateral ocular and skin involvement by juvenile xanthogranuloma and the results of treatment with vinblastine.


METHODS
Analysis of the clinical and histopathologic data and the results of the treatment.


RESULTS
After 14 months' evolution with no response to other treatments, the lesions responded to a course of vinblastine (6 mg/m2/weekly, corrected for weight), which was followed by a maintenance treatment for 52 weeks.


CONCLUSIONS
The treatment protocol used in the present case may prove useful for similar patients. We found no other report describing these results.
Pollono
Daniel
D
Oncology Unit, "Superiora Sor María Ludovica" Children's Hospital, La Plata - Argentina. danielpo@netverk.com.ar
Galan
Marta
M
Curuchet
Adriana
A
Drut
Ricardo
R
Pollono
Agustina
A
Rodriguez
Jacinto
J
D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005128:Eye Diseases / Q000188:drug therapy / Q000209:etiology*; D007839:Functional Laterality; D006801:Humans; D007223:Infant; D008297:Male; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology; D014747:Vinblastine / Q000627:therapeutic use*; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000188:drug therapy
D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine