title: Peripheral blood CD8+DR+ T-cell count: a potential new immunologic marker of unexplained recurrent abortion.
abstract: A case-control study was performed to assess whether T-cell activation profile of CD8+ T-cells is associated with unexplained recurrent abortion. Women with abortion had significantly higher percentages (32 +/- 11 vs. 24 +/- 13%) and absolute numbers (160 +/- 78 vs. 114 +/- 83 cells/mm(3)) of CD8+DR+ T-cells than controls.
authors.affiliation: Department of Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain. jcarbone.hgugm@salud.madrid.org
authors.forename: Javier
authors.initials: J
authors.lastname: Carbone
authors.forename: Antonio
authors.initials: A
authors.lastname: Gallego
authors.forename: Nallibe
authors.initials: N
authors.lastname: Lanio
authors.forename: Carmen
authors.initials: C
authors.lastname: Chean
authors.forename: Joaquin
authors.initials: J
authors.lastname: Navarro
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Sarmiento
mesh_terms: D000026:Abortion, Habitual / Q000097:blood* / Q000175:diagnosis / Q000276:immunology*; D000328:Adult; D015415:Biomarkers / Q000097:blood; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006684:HLA-DR Antigens / Q000096:biosynthesis* / Q000097:blood; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000276:immunology / Q000378:metabolism; D018655:Lymphocyte Count; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D006684:HLA-DR Antigens