[The no-reflow phenomenon following percutaneous coronary intervention].
The no-reflow phenomenon after successful coronary artery perfusion is caused by a myocardial perfusion defect due to impaired blood flow in the microvascular bed. This phenomenon is more prevalent among acute myocardial infarction patients who have additional cardiovascular risk factors, and its presence constitutes an independent negative prognostic sign. The impaired microvascular myocardial blood flow is caused by microemboli and by intracellular processes taking place during the reperfusion phase. In the last few years, many studies have been published regarding new diagnostic and treatment modalities based on a better understanding of the pathophysiological processes implicated.
Schwartzenberg
Shmuel
S
Department of Cardiology, Sourasky Tel Aviv Medical Center, Tel Aviv, Israel. sschwartzenberg@gmail.com
Halkin
Amir
A
Finkelstein
Ariel
A
Keren
Gad
G
Banai
Shmuel
S
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D003326:Coronary Circulation / Q000502:physiology*; D006801:Humans; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D015427:Reperfusion Injury / Q000503:physiopathology