title: Genentech obtains proof of concept for hedgehog inhibition.
authors.forename: Cormac
authors.initials: C
authors.lastname: Sheridan
mesh_terms: D000813:Anilides / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004331:Drosophila melanogaster; D004345:Drug Industry; D053823:Hedgehog Proteins / Q000037:antagonists & inhibitors*; D006801:Humans; D008024:Ligands; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000473:pathology; D011725:Pyridines / Q000494:pharmacology / Q000627:therapeutic use; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000813:Anilides; D000970:Antineoplastic Agents; D053823:Hedgehog Proteins; C538724:HhAntag691; D008024:Ligands; D011725:Pyridines