title: Hand hygiene for the prevention of nosocomial infections.
abstract: BACKGROUND
  The WHO regards hand hygiene as an essential tool for the prevention of nosocomial infection, but compliance in clinical practice is often low.
  
  
  METHODS
  The relevant scientific literature and national and international evidence-based recommendations (Robert Koch Institute [Germany], WHO) were evaluated.
  
  
  RESULTS
  Hygienic hand disinfection has better antimicrobial efficacy than hand-washing and is the procedure of choice to be performed before and after manual contact with patients. The hands should be washed, rather than disinfected, only when they are visibly soiled. Skin irritation is quite common among healthcare workers and is mainly caused by water, soap, and prolonged wearing of gloves. Compliance can be improved by training, by placing hand-rub dispensers at the sites where they are needed, and by physicians setting a good example for others.
  
  
  CONCLUSIONS
  Improved compliance in hand hygiene, with proper use of alcohol-based hand rubs, can reduce the nosocomial infection rate by as much as 40%.
authors.affiliation: Bode Chemie GmbH, Hamburg.
authors.forename: Günter
authors.initials: G
authors.lastname: Kampf
authors.forename: Harald
authors.initials: H
authors.lastname: Löffler
authors.forename: Petra
authors.initials: P
authors.lastname: Gastmeier
mesh_terms: D003428:Cross Infection / Q000453:epidemiology* / Q000517:prevention & control*; D005858:Germany / Q000453:epidemiology; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006235:Hand Disinfection; D006801:Humans; D017757:Infectious Disease Transmission, Professional-to-Patient / Q000517:prevention & control* / Q000706:statistics & numerical data*; D038622:Internationality; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome