[Risk factors of multiple sclerosis development in the population of the Rostov region].
Based on the results of the descriptive epidemiological investigation, which has revealed the increase in the prevalence of multiple sclerosis (MS) in the Rostov region, a hypothesis on the role of genotype-environment interaction in MS is put forward. The analytical epidemiological case-control study of 122 couples has found significant correlations between MS and pneumonia, with the age at onset under 7 years, food allergy at the age between 7 and 15, the presence of industrial plants in the area of habitation (5 km), the trauma of head and spine at the age over 15, the predominance of animal fat in the diet. The influence of some climate, geographical and ecological factors on the MS prevalence in the population of the Rostov region was assessed.
Goncharova
Z A
ZA
Baliazin
V A
VA
D000293:Adolescent; D002648:Child; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics; D010641:Phenotype; D011159:Population Surveillance; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology