title: Radiofrequency ablation of metastatic pheochromocytoma.
abstract: In the present report on the preliminary safety and effectiveness of radiofrequency (RF) ablation for pheochromocytoma metastases, seven metastases were treated in six patients (mean size, 3.4 cm; range, 2.2-6 cm). alpha- and beta-adrenergic and catecholamine synthesis inhibition and intraprocedural anesthesia monitoring were used. Safety was assessed by recording ablation-related complications. Complete ablation was defined as a lack of enhancement within the ablation zone on follow-up computed tomography. No serious adverse sequelae were observed. Complete ablation was achieved in six of seven metastases (mean follow-up, 12.3 months; range, 2.5-28 months). In conclusion, RF ablation may be safely performed for metastatic pheochromocytoma given careful attention to peri-procedural management.
authors.affiliation: Center for Interventional Oncology, Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland 20892, USA. venkatesana@cc.nih.gov
authors.forename: Aradhana M
authors.initials: AM
authors.lastname: Venkatesan
authors.forename: Julia
authors.initials: J
authors.lastname: Locklin
authors.forename: Edwin W
authors.initials: EW
authors.lastname: Lai
authors.forename: Karen T
authors.initials: KT
authors.lastname: Adams
authors.forename: Antonio Tito
authors.initials: AT
authors.lastname: Fojo
authors.forename: Karel
authors.initials: K
authors.lastname: Pacak
authors.forename: Bradford J
authors.initials: BJ
authors.lastname: Wood
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome