Aggressive small cell carcinoma of the ovary, hypercalcemic type with hypercalcemia in pregnancy, treated with conservative surgery and chemotherapy.
BACKGROUND
Small cell carcinoma of the ovary, hypercalcemic type is a rare and aggressive malignancy found in reproductive-age women.


METHODS
We report a 22-year-old pregnant woman found to have symptomatic paraneoplastic hypercalcemia associated with small cell carcinoma of the ovary, hypercalcemic type. She was primarily treated with conservative surgery and chemotherapy secondary to desired pregnancy. She died of the disease 10 months from primary diagnosis.


CONCLUSIONS
Small cell carcinoma of the ovary, hypercalcemic type is a very aggressive type of ovarian malignancy with a poor prognosis.
McCormick
Timothy Chad
TC
Department of Obstetrics and Gynecology, University of Missouri-Kansas City, Kansas City, MO 64108, USA. txdoc27@yahoo.com
Muffly
Tyler
T
Lu
George
G
Shoup
Brenda
B
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011379:Prognosis; D055815:Young Adult
D000970:Antineoplastic Agents