STUDIES ON THE MECHANISM OF RECOVERY IN PNEUMOCOCCAL PNEUMONIA : III. FACTORS INFLUENCING THE PHAGOCYTOSIS OF PNEUMOCOCCI IN THE LUNG DURING SULFONAMIDE THERAPY.
The phagocytosis which occurs in the lungs of rats receiving sulfonamide is due neither to an opsonizing action of the sulfonamides nor to type-specific antibody. The evidence presented indicates that the destruction of the pneumococci is brought about by a phagocytic mechanism independent of both opsonization and capsular injury.
Wood
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Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore.
McLeod
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D000818:Animals; D003289:Convalescence; D007239:Infections; D008168:Lung; D010586:Phagocytes; D010587:Phagocytosis; D011008:Pneumococcal Infections; D011014:Pneumonia / Q000628:therapy*; D011018:Pneumonia, Pneumococcal; D051381:Rats; D013296:Streptococcus pneumoniae; D000077145:Sulfanilamide; D013424:Sulfanilamides; D013449:Sulfonamides / Q000494:pharmacology*
D013424:Sulfanilamides; D013449:Sulfonamides; D000077145:Sulfanilamide