Embryogenesis: Degenerate phosphatases control the oocyte-to-embryo transition.
The oocyte-to-embryo transition requires drastic reorganizations within a short timeframe. Recent studies show that, in the nematode Caenorhabditis elegans, phosphotyrosine-binding pseudo-phosphatases are key regulators of this critical developmental transition.
Heighington
Cassandra S
CS
Departments of Genetics, University of Georgia, Athens, 30602, USA.
Kipreos
Edward T
ET
D000818:Animals; D001665:Binding Sites; D017173:Caenorhabditis elegans / Q000166:cytology / Q000196:embryology* / Q000201:enzymology; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D047108:Embryonic Development / Q000502:physiology*; D019000:Phosphotyrosine / Q000378:metabolism; D017027:Protein Tyrosine Phosphatases / Q000737:chemistry / Q000502:physiology*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism* / Q000502:physiology
D029742:Caenorhabditis elegans Proteins; C545208:EGG-4 protein, C elegans; C545209:EGG-5 protein, C elegans; D019000:Phosphotyrosine; C478059:MBK-2 protein, C elegans; D011505:Protein-Tyrosine Kinases; C525138:EGG-3 protein, C elegans; D017027:Protein Tyrosine Phosphatases