title: [The problem of myocardial heterogeneity].
abstract: In this paper, we present a review of modern data on the myocardial heterogeneity. Data obtained by different authors as well as our own results clearly show that cardiac muscle is an essentially heterogeneous system at every level of organization: from molecular to organ. Cardiomyocyte function in the myocardial system is closely coordinated: both temporarily and spatially, with complex motion of cardiac chamber walls. Spatio-temporal heterogeneity of left ventricular wall motion is considered as its fundamental attribute. An index of spatio-temporal heterogeneity of left ventricular wall motion suggested by authors is shown to reflect an essential variable that regulates or modulates left ventricular mechanical function.
authors.forename: V S
authors.initials: VS
authors.lastname: Markhsin
authors.forename: O
authors.initials: O
authors.lastname: Solov'eva
authors.forename: T V
authors.initials: TV
authors.lastname: Chumarnaia
authors.forename: S V
authors.initials: SV
authors.lastname: Sukhareva
mesh_terms: D000818:Animals; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction / Q000502:physiology*; D009206:Myocardium; D032383:Myocytes, Cardiac / Q000502:physiology*