title: Primary open angle glaucoma and intraocular pressure in patients with systemic hypertension.
abstract: OBJECTIVE
  To investigate the association between Primary Open Angle Glaucoma (POAG), Intraocular Pressure (IOP) and systemic hypertension.
  
  
  METHODS
  Cross-sectional, convenient and controlled study.
  
  
  METHODS
  Eye Clinic of the Lagos University Teaching hospital, Idi-Araba, Lagos, Nigeria.
  
  
  METHODS
  Consecutive newpatients with documented history of hypertension medication of over three months and current attendees at hypertension clinic of the same hospital were enrolled into the study.
  
  
  RESULTS
  A total of 150 hypertensive patients and 50 age-sex matched controls were studied. Age range of hypertensives was 34-54 years and controls 31-71 years. The mean age for hypertensive group was 56 years (+/- 12.95) and controls 54.76 years (+/- 9.65) p > 0.1. The mean IOP was 28.45 mmHg (+/- 10.3) in hypertensive group and 15.2 mmHg (+/- 5.09) in controls (P < 0.001). POAG was present in 58 (38.7%) of the hypertensive patients whilst only nine (18.0%) had POAG in control group (p < 0.01 odds ratio: 22). lOP > 21 mmHg was found in 28 (18.7) of hypertensive group and two (4.0%) of the control (p < 0.01 odds ratio 4.7).
  
  
  CONCLUSIONS
  Systemic hypertension showed a modest positive association with elevated intraocular pressure. The strong relationship with IOP in part supports the association with POAG.
authors.affiliation: Guinness Eye Centre, Lagos University Teaching Hospital/College of Medicine, University of Lagos, Idi-Araba, PMB 12003, Lagos, Nigeria.
authors.forename: A O
authors.initials: AO
authors.lastname: Onakoya
authors.forename: J N
authors.initials: JN
authors.lastname: Ajuluchukwu
authors.forename: H L
authors.initials: HL
authors.lastname: Alimi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D016017:Odds Ratio; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents