title: Management of Frey syndrome using botulinum neurotoxin: a case report.
abstract: Frey syndrome is manifested clinically by hemifacial flushing and sweating after a gustatory stimulus. Frey syndrome is usually secondary to traumatic injury in the parotid region and is thought to be the result of misdirected re-sprouting of damaged autonomic nerve fibres. In this case report, we highlight the clinical and psychosocial aspects of Frey syndrome from a patient"s perspective, outline the pathophysiology of the condition and current management strategies, and describe the use of botulinum neurotoxin in the treatment of Frey syndrome.
authors.affiliation: Oral oncology/dentistry clinic, British Columbia Cancer Agency, Vancouver, British Columbia. dr.s.ng@opusoralhealth.ca
authors.forename: Samson
authors.initials: S
authors.lastname: Ng
authors.forename: Cathy
authors.initials: C
authors.lastname: Torjek
authors.forename: Allan
authors.initials: A
authors.lastname: Hovan
mesh_terms: D008949:Adenoma, Pleomorphic / Q000601:surgery; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007202:Indicators and Reagents; D007455:Iodine; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D010307:Parotid Neoplasms / Q000601:surgery; D011183:Postoperative Complications; D013213:Starch; D013547:Sweating, Gustatory / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D007202:Indicators and Reagents; D009465:Neuromuscular Agents; D013213:Starch; D007455:Iodine; D019274:Botulinum Toxins, Type A