STUDIES ON A LUNG TISSUE COMPONENT WHICH COMBINES WITH PNEUMONIA VIRUS OF MICE (PVM).
Evidence has been obtained which indicates that the lung tissues of mammalian species susceptible to infection with PVM contain a specific component which combines with the virus. The concentration of this tissue component appears to be directly proportional to the suceptibility of the species; in its absence infection with PVM cannot be established. The available evidence suggests that the presence of the virus-combining component in lung tissue may play a decisive ro1e in the initiation of infection with this pneumotropic virus.
Volkert
M
M
Hospital of The Rockefeller Institute for Medical Research.
Horsfall
F L
FL
D000818:Animals; D008168:Lung; D051379:Mice; D029122:Murine pneumonia virus; D011014:Pneumonia