title: [Regional audit on fluoroquinolones usage in the hospital and the community: are these antibiotics over-used?].
abstract: OBJECTIVE
  The ecological impact of an over-use or a mis-use of fluoroquinolones (FQs) appears of great importance according to published data. With the objective to set up a regional antibiotic stewardship program, we conducted a regional audit on FQs usage.
  
  
  METHODS
  [corrected] Ninety general practionners and 15 health care facilities participated to this prospective study. Overall, 511 prescriptions were evaluated (276 from hospital physicians and 235 [46%] from general practionners). The compliance of FQs prescription with national recommendations and with a regional referential was assessed. This regional referential was established in order to preserve FQs.
  
  
  RESULTS
  Only 14,3% of the prescriptions complied with the regional referential, even if the choice of FQs were in accordance with national recommendations in 56,8% of the prescriptions. Urinary tract infections (mostly non-complicated) were the most common indication for FQs prescription.
  
  
  CONCLUSIONS
  Analysis of FQs prescriptions shows that there is a significant potential for FQs preservation in Franche-Comté.
authors.affiliation: Service des maladies infectieuses et tropicales, pôle gestion du risque infectieux et sanitaire, CHU de Besançon, 25030 Besançon, France.
authors.forename: J
authors.initials: J
authors.lastname: Leroy
authors.forename: I
authors.initials: I
authors.lastname: Patry
authors.forename: C
authors.initials: C
authors.lastname: Faure
authors.forename: E
authors.initials: E
authors.lastname: Ariskina
authors.forename: J-P
authors.initials: JP
authors.lastname: Gaume
authors.forename: T
authors.initials: T
authors.lastname: Hénon
authors.forename: O
authors.initials: O
authors.lastname: Ruyer
authors.forename: J-P
authors.initials: JP
authors.lastname: Faller
authors.forename: B
authors.initials: B
authors.lastname: Hoen
authors.forename: X
authors.initials: X
authors.lastname: Bertrand
authors.forename: D
authors.initials: D
authors.lastname: Talon
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage*; D054869:Clinical Audit; D024841:Fluoroquinolones / Q000008:administration & dosage*; D058006:General Practice; D019983:Guideline Adherence; D006761:Hospitals; D006801:Humans; D010818:Practice Patterns, Physicians'; D055553:Prescription Drugs
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D055553:Prescription Drugs