title: Desymmetrization of cyclic meso-epoxides with silicon tetrachloride catalyzed by PINDOX, a chiral bipyridine mono-N-oxide.
abstract: PINDOX 8 has been identified as a chiral organocatalyst for the enantioselective ring-opening of cyclic meso-epoxides with SiCl(4) to produce chlorohydrins in up to 90% ee. The catalyst is most effective with saturated cyclic substrates containing more than seven carbon units.
authors.affiliation: Department of Chemistry, WestChem, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK. a.malkoV@lboro.ac.uk
authors.forename: Andrei V
authors.initials: AV
authors.lastname: Malkov
authors.forename: Malcolm R
authors.initials: MR
authors.lastname: Gordon
authors.forename: Sigitas
authors.initials: S
authors.lastname: Stoncius
authors.forename: Javid
authors.initials: J
authors.lastname: Hussain
authors.forename: Pavel
authors.initials: P
authors.lastname: Kocovský