title: [Study on refining process of Flos Chrysanthemi extract with macroporous resin].
abstract: OBJECTIVE
  To determine the parameters of refining process of Flos Chrysanthemi extract with macroporous adsorption resin.
  
  
  METHODS
  According to the chlorogenic acid and total flavonoids, to investigate the kind of macoroporous resin, the maximum quantity of physic liquor, and the type and quantity of elution solvent. Then combining with the retention rate of luteolin, to verify the parameters of the process.
  
  
  RESULTS
  The maximum adsorption quantity of chlorogenic acid was 10.8 mg/g dry resin, and the elution solvent was 5-fold column volume of 80% alcohol; the purity of total flavonoids, chlorogenic acid and luteolin were 589.2%, 605.4%, 650.1%, respectively.
  
  
  CONCLUSIONS
  The resin F can enrich the active components of Flos Chrysanthemi effectively.
authors.affiliation: HE Xian Memorial Hospital, Panyu District of Guangzhou City, Guangzhou 511400, China. gzpyyhy@126.com
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Yu
authors.forename: Yan-Qing
authors.initials: YQ
authors.lastname: Li
authors.forename: Li-Xiong
authors.initials: LX
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Gang
authors.initials: G
authors.lastname: Wei
mesh_terms: D000327:Adsorption; D002726:Chlorogenic Acid / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D031202:Chrysanthemum / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D000431:Ethanol / Q000737:chemistry; D005419:Flavonoids / Q000032:analysis; D035264:Flowers / Q000737:chemistry*; D047311:Luteolin / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry; D012117:Resins, Synthetic / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D012117:Resins, Synthetic; D002726:Chlorogenic Acid; D000431:Ethanol; D047311:Luteolin