Steady state fluorescence spectroscopic technique to reveal the thermodynamics of fragmentation of compound induced alpha-cyclodextrin nanotubular suprastructures.
Calorimetric titration technique using flow devices is generally used to understand the thermodynamics of nanotubular suprastructure formations, however high concentrations of the guest molecules used may disrupt the suprastructures. This report shows thermodynamic information can also be obtained by the implementation of fluorescence spectroscopy. Denaturants break nanotubular assembly created by the guest molecule leading to change in guest fluorescence on altering the denaturant concentration. This phenomenon can be monitored to get the relative change in enthalpy in the process of fragmentation of the nanotubular structures along with the change in the standard free energy. The fluorescence technique uses appropriate concentration of the guest molecules required to form nanotubular suprastructures.
Jaffer
Syed S
SS
Department of Chemistry, Birla Institute of Technology and Science, Pilani 333 031, Rajasthan, India.
Purkayastha
Pradipta
P