Robust embryo identification using first polar body single nucleotide polymorphism microarray-based DNA fingerprinting.
This study sought to validate a novel, minimally invasive system for embryo tracking by single nucleotide polymorphism microarray-based DNA fingerprinting of the first polar body. First polar body-based assignments of which embryos implanted and were delivered after multiple ET were 100% consistent with previously validated embryo DNA fingerprinting-based assignments.
Treff
Nathan R
NR
Reproductive Medicine Associates of New Jersey, Morristown, New Jersey, USA. ntreff@rmanj.com
Su
Jing
J
Kasabwala
Natasha
N
Tao
Xin
X
Miller
Kathleen A
KA
Scott
Richard T
RT
D000328:Adult; D001706:Biopsy; D001755:Blastocyst / Q000166:cytology* / Q000378:metabolism* / Q000473:pathology; D001757:Blastomeres / Q000166:cytology / Q000378:metabolism / Q000473:pathology; D004247:DNA / Q000302:isolation & purification / Q000378:metabolism; D016172:DNA Fingerprinting / Q000379:methods*; D004624:Embryo Transfer / Q000379:methods; D005260:Female; D005307:Fertilization in Vitro; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D046228:Microarray Analysis / Q000379:methods*; D009061:Mouth Mucosa / Q000737:chemistry / Q000378:metabolism; D010355:Patient Identification Systems / Q000379:methods; D020641:Polymorphism, Single Nucleotide; D011247:Pregnancy; D035781:Siblings
D004247:DNA