THE MODIFYING EFFECTS OF CERTAIN SUBSTANCES OF BACTERIAL ORIGIN ON THE COURSE OF INFECTION WITH PNEUMONIA VIRUS OF MICE (PVM).
Evidence is presented which indicates that certain polysaccharide preparations derived from various bacterial species, as well as similar materials not of bacterial origin, are capable of lessening the severity of infection with pneumonia virus of mice (PVM) and inhibiting multiplication of the virus in mouse lungs infected with this agent. It seems probable that modification with respect to the virus is mediated by a substance which may be polysaccharide in nature.
Horsfall
F L
FL
Hospital of The Rockefeller Institute for Medical Research.
McCarty
M
M
D000818:Animals; D010450:Endopeptidases; D006867:Hydrolases; D007106:Immune Sera; D051379:Mice; D029122:Murine pneumonia virus; D010447:Peptide Hydrolases; D011014:Pneumonia; D011134:Polysaccharides; D044967:Serum; D014780:Viruses
D007106:Immune Sera; D011134:Polysaccharides; D006867:Hydrolases; D010450:Endopeptidases; D010447:Peptide Hydrolases