title: The relationship of self-reported pain and functional impairment to gait mechanics in overweight and obese persons with knee osteoarthritis.
abstract: OBJECTIVE
  To examine the degree to which 2 commonly used measures of pain and disability, the Arthritis Impact Measurement Scales (AIMS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), relate to objective gait measurements.
  
  
  METHODS
  A descriptive study of the influence of self-reported pain and perceived functional impairment on gait mechanics in osteoarthritic adults.
  
  
  METHODS
  A university clinical research laboratory.
  
  
  METHODS
  Overweight/obese adults with radiographic knee osteoarthritis (OA) as well as pain and disability associated with the disease (N=179).
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  The AIMS and WOMAC were administered to determine self-report measures of pain and disability. Speed, stride length, support time, knee angle, and peak vertical force (PVF) were determined from 3-dimensional kinematic and kinetic data collected on subjects walking at self-selected normal and fast speeds. Anthropometric data and radiographic levels of OA were also collected.
  
  
  RESULTS
  Pearson correlation analysis showed that the AIMS physical disability score was inversely correlated with speed, stride length, and knee range of motion at both speeds and PVF at the fast speed. The WOMAC function score was inversely correlated with speed and stride length at both speeds and with PVF at fast speed. The WOMAC pain score was inversely correlated with speed and PVF at the fast speed. Regression analysis revealed that the AIMS physical disability score and body mass index accounted for the greatest variation in speed at the normal speed. Overall, AIMS physical disability and WOMAC function explained a larger proportion of variance in gait mechanics than radiographic measures of OA disease severity.
  
  
  CONCLUSIONS
  Taken together, the results suggest that the AIMS physical disability and WOMAC function scores are associated with some important measures of gait impairment.
authors.affiliation: Department of Biological Anthropology and Anatomy, Duke University, Durham, NC, USA.
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Nebel
authors.forename: Ershela L
authors.initials: EL
authors.lastname: Sims
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Keefe
authors.forename: Virginia B
authors.initials: VB
authors.lastname: Kraus
authors.forename: Farshid
authors.initials: F
authors.lastname: Guilak
authors.forename: David S
authors.initials: DS
authors.lastname: Caldwell
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Pells
authors.forename: Robin
authors.initials: R
authors.lastname: Queen
authors.forename: Daniel
authors.initials: D
authors.lastname: Schmitt
mesh_terms: D004185:Disability Evaluation; D006233:Persons with Disabilities; D005260:Female; D005684:Gait / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D020370:Osteoarthritis, Knee / Q000503:physiopathology*; D050177:Overweight; D010146:Pain / Q000209:etiology* / Q000503:physiopathology*; D010147:Pain Measurement; D012044:Regression Analysis; D012650:Self Disclosure