[Retinal vein occlusion followed by ischemic optic neuropathy with anticardiolipin IgG antibody: a case report].
BACKGROUND
Anticardiolipin antibodies in the autoimmune mechanism can cause vasculitis, leading to hypercoagulability-related thrombosis. We report a case of retinal vein occlusion followed by ischemic optic neuropathy in a young woman with anticardiolipin IgG antibody.


METHODS
A 17-year-old woman with dilatation and tortuosity of the retinal veins and retinal hemorrhage in the superior quadrant of the retina OS. Fluorescein retinal angiography showed a delay of filling time in the upper quadrant of the retina and a 3mm-continuous stain along the superior retinal vein. Laboratory tests were repeatedly positive for anticardiolipin IgG antibodies. Although the retinal hemorrhage disappeared 2 months after subtennon injection of 20 mg triamcinolone acetonide (TA), ischemic optic neuropathy occurred 9 months later.


CONCLUSIONS
The staining of the vessel wall and the effectiveness of TA suggest that vasculitis may be associated with the pathology of this condition. The presence of anticardiolipin IgG antibodies suggests that autoimmune mechanism is involved in the vasculitis.
Yamamoto
Takami
T
Ideta Eye Hospital. takami_y@hotmail.co.jp
Mimura
Osamu
O
Kawasaki
Tsutomu
T
Ideta
Ryuichi
R
Ideta
Hidenao
H
D000293:Adolescent; D001323:Autoantibodies / Q000097:blood*; D002308:Cardiolipins / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D018917:Optic Neuropathy, Ischemic / Q000209:etiology* / Q000276:immunology; D012170:Retinal Vein Occlusion / Q000150:complications* / Q000276:immunology
D001323:Autoantibodies; D002308:Cardiolipins; D007074:Immunoglobulin G