title: Candida albicans isolated from human fungaemia induces apoptosis in an experimental endocarditis model.
abstract: Candida albicans is the most common fungal pathogen known to cause endovascular infections, such as vascular catheter sepsis, infections of vascular prostheses and infective endocarditis. A C. albicans isolate was used to determine the apoptotic potential of the fungus in a rat endocarditis model. This study confirms the ability of C. albicans to induce apoptosis in myocardial tissue.
authors.affiliation: Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
authors.forename: Iván
authors.initials: I
authors.lastname: Hernández-Cañaveral
authors.forename: Gerardo
authors.initials: G
authors.lastname: Becerra
authors.forename: Alberto
authors.initials: A
authors.lastname: Jiménez-Cordero
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Michel
authors.forename: Arturo
authors.initials: A
authors.lastname: Plascencia
authors.forename: Miguel
authors.initials: M
authors.lastname: Domínguez-Hernández
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002176:Candida albicans / Q000472:pathogenicity*; D002177:Candidiasis / Q000382:microbiology*; D004195:Disease Models, Animal; D004696:Endocarditis / Q000382:microbiology*; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D051381:Rats; D013997:Time Factors