Fe-catalyzed highly selective ring expansion of alkynylcyclopropyl alkanols to cyclobutanols.
A Fe-catalytic highly selective ring expansion reaction of alkynylcyclopropyl alkanols to alkynylcyclobutanols via a 1,2-carbon shift under mild conditions was developed. A new class of homogeneous FeCl(2)/O(2) catalytic system was employed in these novel transformations.
Chen
Anjun
A
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China.
Lin
Riyuan
R
Liu
Qingjian
Q
Jiao
Ning
N
D002384:Catalysis; D003503:Cyclobutanes / Q000138:chemical synthesis*; D004988:Ethers, Cyclic / Q000737:chemistry*; D005296:Ferrous Compounds; D010100:Oxygen
D003503:Cyclobutanes; D004988:Ethers, Cyclic; D005296:Ferrous Compounds; C538814:cyclobutanol; C043657:cyclopropanol; C029451:ferrous chloride; D010100:Oxygen