Indirect mechanisms of carcinogenesis via downregulation of PTEN function.
Leslie
Nick R
NR
Division of Molecular Physiology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Spinelli
Laura
L
Tibarewal
Priyanka
P
Zilidis
Georgios
G
Weerasinghe
Nimmi
N
Lim
Joseph C
JC
Maccario
Helene
H
Downes
C Peter
CP
D000818:Animals; D002471:Cell Transformation, Neoplastic; D015536:Down-Regulation; D056827:Endosomal Sorting Complexes Required for Transport / Q000235:genetics / Q000378:metabolism; D020690:GTPase-Activating Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D024701:Myosin Type V / Q000235:genetics / Q000378:metabolism; D000075702:Nedd4 Ubiquitin Protein Ligases; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D054731:PDZ Domains; D051059:PTEN Phosphohydrolase / Q000235:genetics / Q000378:metabolism*; D010750:Phosphoproteins / Q000235:genetics / Q000378:metabolism; D011485:Protein Binding; D015398:Signal Transduction / Q000502:physiology; D017923:Sodium-Hydrogen Exchangers / Q000235:genetics / Q000378:metabolism; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism; D051636:X-Linked Inhibitor of Apoptosis Protein / Q000235:genetics / Q000378:metabolism
D056827:Endosomal Sorting Complexes Required for Transport; D020690:GTPase-Activating Proteins; D009363:Neoplasm Proteins; D010750:Phosphoproteins; D017923:Sodium-Hydrogen Exchangers; D025521:Tumor Suppressor Proteins; D051636:X-Linked Inhibitor of Apoptosis Protein; C093376:sodium-hydrogen exchanger regulatory factor; D000075702:Nedd4 Ubiquitin Protein Ligases; D044767:Ubiquitin-Protein Ligases; D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human; D024701:Myosin Type V