[Alkaloids from Macleaya cordata].
OBJECTIVE
To study the alkaloids of Macleaya cordata.


METHODS
The alkaloids were isolated and purified by various column chromatography as well as recrystallization. Their structures were identified by physico-chemical properties and spectral analysis.


RESULTS
Thirteen alkaloids were isolated and identified as 6-methoxy-dihydrosanguinarine (1), norsanguinarine (2), 6-acetonyl-dihyrochelerythrine (3), 6-acetonyl-dihyrosanguinnarine (4), sanguidimerine (5), chelidimerine (6), (+/-) -bocconarborine A (7), (+/-)-bocconarborine B (8), cryptopine (9), dihydrosanguinarine (10), dihydrochelerythrine (11), protopine (12), alpha-allocryptopine (13).


CONCLUSIONS
Compounds 2, 3, 5 - 9 were firstly isolated from the genus Macleaya and compound 1 was obtained from M. cordata for the first time.
Ye
Fengzhi
F
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
Feng
Feng
F
Liu
Wenyuan
W
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D028101:Papaveraceae / Q000737:chemistry*
D000470:Alkaloids; D004365:Drugs, Chinese Herbal