title: The putative role of the venous system in the genesis of vascular malformations.
abstract: Recent clinical and experimental evidence has challenged the traditional concept of the venous system as a "passive" element in the genesis and evolution of intracranial vascular malformations. The authors review the clinical and experimental evidence linking the venous system and its anomalies to the genesis of various intracranial vascular malformations, including dural arteriovenous fistulas, cavernous malformations, parenchymal arteriovenous malformations, and capillary telangiectasia. They also describe the potential significance of different associations of these vascular anomalies.
authors.affiliation: Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Mariam S
authors.initials: MS
authors.lastname: Aboian
authors.forename: David J
authors.initials: DJ
authors.lastname: Daniels
authors.forename: Stylianos K
authors.initials: SK
authors.lastname: Rammos
authors.forename: Eugenio
authors.initials: E
authors.lastname: Pozzati
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lanzino
mesh_terms: D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology; D020785:Central Nervous System Vascular Malformations / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D002533:Cerebral Angiography; D002550:Cerebral Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D015897:Comorbidity; D006801:Humans; D015994:Incidence; D019635:Neurosurgical Procedures; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000453:epidemiology