title: Impact of plasmatic lipids in glycemic control and its influence in the cardiometabolic risk in morbidly obese subjects.
abstract: OBJECTIVE
  To evaluate whether biochemical parameters are associated with a good glycemic control and to identify the occurrence of cardiometabolic risk variables.
  
  
  METHODS
  One hundred forty Brazilians were evaluated. The subjects were characterized with regard to glycemic control as good, fair and poor and were divided into tertiles by TG and HbA(1c). We use the ROC curve to determine which variables were predicted of poor glycemic control and the factor analyses to identify the domains that segregated among the risk variables.
  
  
  RESULTS
  Fasting glucose and insulin levels, TG level, VLDL-C and HOMA-IR increased significantly across HbA(1c) tertiles. The best marker for identification of poor glycemic control was triglycerides. The presence of cardiometabolic abnormalities did not alter the glycemic control, but HOMA-IR was significantly higher in subjects with abnormalities.
  
  
  CONCLUSIONS
  The use of TG levels offers a reasonable degree of clinical utility. In morbidly obese subjects insulin resistance is associated with individual cardiometabolic factors.
authors.affiliation: Faculdade de Medicina do ABC, Santo André, SP, Brasil.
authors.forename: Ary
authors.initials: A
authors.lastname: Serpa Neto
authors.forename: Felipe Martin Bianco
authors.initials: FM
authors.lastname: Rossi
authors.forename: Rodrigo Dal Moro
authors.initials: RD
authors.lastname: Amarante
authors.forename: Nara Alves
authors.initials: NA
authors.lastname: Buriti
authors.forename: Marçal
authors.initials: M
authors.lastname: Rossi
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology; D015243:Cholesterol, VLDL / Q000097:blood; D005215:Fasting / Q000097:blood; D005260:Female; D006706:Homeostasis; D006801:Humans; D007328:Insulin / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000209:etiology; D009767:Obesity, Morbid / Q000097:blood* / Q000150:complications; D012372:ROC Curve; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D015243:Cholesterol, VLDL; D007328:Insulin; D008055:Lipids; D014280:Triglycerides