title: Relationship between the prevalence of the dentigerous cyst and the odontogenic keratocyst tumor and the current etiologic hypothesis.
abstract: Cysts are considered as nonneoplastic benign lesions that, when present for a long period of time, can cause some discomfort, especially related to the treatment form. Among the types of cysts of the maxilla, the dentigerous cyst (DC) presents substances between the dental follicle and the crown of the tooth with high potential for resorption, and the odontogenic keratocyst tumor (OKT) characterizes for its noticed rapid growth pattern and the possibility to develop carcinomas in the lesion wall. The DC is the most common type among the developing odontogenic cystic lesions, while the OKT represents 10% of these lesions. The prevalence of the OKT found in the current study was superior to the DC, opposing data of the evaluated literature, as well as the predominance in relation to the age group. Dentigerous cyst cases were found mostly in younger individuals, whereas the OKT was observed mainly in individuals between the third and fourth decades of life. This fact reflects the fragility of these features while establishing the presumptive diagnosis and insinuates the strong relation with a probable genetic predisposition. In relation to sex and race, the findings in this article were similar to those found in the literature, highlighting the possibility of a hormonal involvement. However, the anatomopathologic examination remains essential to define the main diagnosis of the lesions observed by means of imaging examinations, providing for safer diagnoses to plan the treatment.
authors.affiliation: Department of Diagnosis and Surgery, Araraquara Dental School, São Paulo State University, Araraquara, São Paulo, Brazil.
authors.forename: Erica Dorigatti
authors.initials: ED
authors.lastname: de Avila
authors.forename: Rafael Scaf
authors.initials: RS
authors.lastname: de Molon
authors.forename: Elaine Maria S
authors.initials: EM
authors.lastname: Massucato
authors.forename: Eduardo
authors.initials: E
authors.lastname: Hochuli-Vieira
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002471:Cell Transformation, Neoplastic; D002648:Child; D003803:Dentigerous Cyst / Q000150:complications / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D007573:Jaw Neoplasms / Q000150:complications / Q000453:epidemiology* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000150:complications / Q000453:epidemiology* / Q000235:genetics; D015995:Prevalence; D012189:Retrospective Studies; D012744:Sex Ratio; D014095:Tooth, Impacted / Q000209:etiology; D055815:Young Adult