[Studies on the chemical constituents of Epimedium brevicornum].
OBJECTIVE
To study the chemical constituents of Epimedium breviconum.


METHODS
Compounds were purificated with various chromatographic techniques such as silica vacuum liquid chromatography and Sephadex LH-20 column chromatography. Their structures were elucidated by physico-chemical methods and spectral analysis.


RESULTS
Ten compounds were obtained and indentified as (7R, 8S) 4,9-dihydroxyl-3,3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9'-O-alpha-L-rhamnopyranoside (1), (7R, 8S, 8' R) 4, 4', 8', 9-tetrahydroxyl-3, 3'-dimethyoxyl-7, 9'-monoepoxylignan (2), (+)-cycloolivil (3), (3, 5, 7, 4')-tetrahydroxyl-8-isopentene group flavonoids-3-O-alpha-L-rhamnopyranoside (4), beta-sitosterol (5), p-hydroxybenzaldehyde (6), succinic acid (7) and p-hydroxyphenethyl (8).


CONCLUSIONS
Compound 1 is isolated from this genus for the first time. Compounds 2,3,5 -8 are isolated from the plant for the first time.
Yang
Yun
Y
Pharmacy College of Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China. yyun@china.com.cn
Zhang
Han-Juan
HJ
Zhu
Zhen-Hua
ZH
He
Hai-Hua
HH
D015078:2-Hydroxyphenethylamine; D001547:Benzaldehydes / Q000737:chemistry / Q000302:isolation & purification*; D034181:Epimedium / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009005:Monosaccharides / Q000737:chemistry / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification*; D019802:Succinic Acid / Q000737:chemistry / Q000302:isolation & purification
C483807:(7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside; D001547:Benzaldehydes; D017705:Lignans; D009005:Monosaccharides; D010636:Phenols; D012855:Sitosterols; C542655:cycloolivil; C025473:gamma-sitosterol; D015078:2-Hydroxyphenethylamine; D019802:Succinic Acid; C011483:4-hydroxybenzaldehyde