[Eosinophilia--pathogenesis, classification and therapy].
Eosinophilia represents a complex clinical problem, the management of which is based on case history and clinical examination. Allergy, parasitic infection or inflammation may then be identified or malignancy suspected. In some cases, representing a haematologic disorder, clonality is demonstrated only by specific tests. The diagnostic and therapeutic approach, including a new classification for eosinophilia, is reviewed, and the importance of molecular biological technique is highlighted. Unexplained eosinophilia should be managed in collaboration with a haematology department.
Andersen
Christen Lykkegaard
CL
Rigshospitalet, Haematologisk Klinik, Vejle og Give Sygehuse, Haematologisk Afdeling, Herlev Hospital, Denmark. christenla@gmail.com
Vestergaard
Hanne
H
Nørgaard
Peter
P
Felding
Peter
P
Pallisgaard
Niels
N
Rasmussen
Inge Hellegaard
IH
Hasselbalch
Hans Carl
HC
Bjerrum
Ole Weis
OW
D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000473:pathology; D025202:Molecular Diagnostic Techniques; D012307:Risk Factors