Creatine metabolism in skeletal muscles during hypokinesia.
Reduction of creatine and creatine-phosphate level was revealed in skeletal muscles of mice during 28-day tail suspension test. Addition of a mixture of amino acids-precursors of creatine and branch-chained amino acids in the ratio 1:1 to ration prevented creatine and creatine-phosphate loss in muscles under the used experimental conditions.
Stogov
M V
MV
G. A. Ilizarov Russian Research Center for Restorative Traumatology and Ortopaedics, Federal Agency for High Technology Medical Aid, Kurgan, Russia. office@ilizarov.ru
D000818:Animals; D003401:Creatine / Q000378:metabolism*; D019417:Hindlimb Suspension; D018476:Hypokinesia / Q000378:metabolism*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D018482:Muscle, Skeletal / Q000378:metabolism*
D003401:Creatine