Amplified detection of protein cancer biomarkers using DNAzyme functionalized nanoprobes.
The high sensitive immunoassay of protein cancer biomarkers is achieved by using of peroxidase-mimicking DNAzyme heavily functionalized gold nanoparticles as catalytic probe.
Zhou
Wen-Hui
WH
College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao, 266003, PR China.
Zhu
Chun-Ling
CL
Lu
Chun-Hua
CH
Guo
Xiuchun
X
Chen
Farong
F
Yang
Huang-Hao
HH
Wang
Xiaoru
X
D014408:Biomarkers, Tumor / Q000032:analysis*; D021881:DNA, Catalytic; D006046:Gold; D006801:Humans; D007118:Immunoassay / Q000379:methods* / Q000592:standards; D053768:Metal Nanoparticles / Q000737:chemistry*; D018716:Molecular Mimicry; D015335:Molecular Probes; D009363:Neoplasm Proteins / Q000032:analysis*; D009195:Peroxidase
D014408:Biomarkers, Tumor; D021881:DNA, Catalytic; D015335:Molecular Probes; D009363:Neoplasm Proteins; D006046:Gold; D009195:Peroxidase