title: NNDB: the nearest neighbor parameter database for predicting stability of nucleic acid secondary structure.
abstract: The Nearest Neighbor Database (NNDB, http://rna.urmc.rochester.edu/NNDB) is a web-based resource for disseminating parameter sets for predicting nucleic acid secondary structure stabilities. For each set of parameters, the database includes the set of rules with descriptive text, sequence-dependent parameters in plain text and html, literature references to experiments and usage tutorials. The initial release covers parameters for predicting RNA folding free energy and enthalpy changes.
authors.affiliation: Department of Chemistry and Center for RNA Biology, Box 0216, University of Rochester, Rochester, NY 14627-0216, USA.
authors.forename: Douglas H
authors.initials: DH
authors.lastname: Turner
authors.forename: David H
authors.initials: DH
authors.lastname: Mathews
mesh_terms: D000465:Algorithms; D001483:Base Sequence; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D012313:RNA / Q000737:chemistry*; D012984:Software; D013816:Thermodynamics
chemical_list: D012313:RNA