title: Radiation-induced spindle cell sarcoma: a rare case report.
abstract: Ionizing radiation has been known to induce malignant transformation in human beings. Radiation-induced sarcomas are a late sequel of radiation therapy. Most sarcomas have been reported to occur after exposure to a radiation dose of 55 Gray (Gy) and above, with a dose ranging from 16 to 112 Gys. Spindle cell sarcomas, arising after radiotherapy given to treat the carcinoma of head and neck region is a very uncommon sequel. This is a rare case report of spindle cell sarcoma of left maxilla, in a 24-year-old male, occurring as a late complication of radiotherapy with Cobalt-60 given for the treatment of retinoblastoma of the left eye 21 years back.
authors.affiliation: Department of Oral Medicine and Radiology, Government Dental College and Research Institute, Bangalore, India.
authors.forename: Mubeen
authors.initials: M
authors.lastname: Khan
authors.forename: Rupa
authors.initials: R
authors.lastname: Chandramala
authors.forename: Ridhima
authors.initials: R
authors.lastname: Sharma
authors.forename: K R
authors.initials: KR
authors.lastname: Vijayalakshmi
mesh_terms: D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D011829:Radiation Dosage; D011839:Radiation, Ionizing; D011878:Radiotherapy / Q000009:adverse effects; D035583:Rare Diseases; D019572:Retinal Neoplasms / Q000532:radiotherapy*; D012175:Retinoblastoma / Q000532:radiotherapy*; D012509:Sarcoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult