Preview. The Tortoise, the hare, and the FoxO.
Maintaining stem cell quiescence is intimately connected to preserving long-term self-renewal potential. In this issue of Cell Stem Cell,Paik et al. (2009) and Renault et al. (2009) demonstrate a role for FoxO transcription factors in regulating neural stem cell proliferation and in maintaining stem and progenitor cell homeostasis.
Chen
Edmund
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Translational Medicine Branch, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA.
Finkel
Toren
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