Improvement of respiratory compromise through abductor reinnervation and pacing in a patient with bilateral vocal fold impairment.
OBJECTIVE
To determine whether respiratory compromise from bilateral vocal fold impairment (paralysis) can be objectively alleviated by reinnervation and pacing.


METHODS
A patient with paramedian vocal folds and synkinesis had a tracheotomy for stridor after bilateral laryngeal nerve injury and Miller Fisher syndrome. One posterior cricoarytenoideus (PCA) received a nerve-muscle pedicle fitted with a perineural electrode for pacemaker stimulation. The airway was evaluated endoscopically and by spirometry for up to 1 year.


RESULTS
Bilateral vocal fold patency during quiet breathing was reversed to active vocal fold adduction during tracheal occlusion. Peak inspiratory flows (PIFs) were significantly higher (P < .001) after reinnervation. PIFs and glottic apertures increased further under stimulation (42 Hz, 1-4 mA, 42-400 microsec). although the differences were not significant.


CONCLUSIONS
Based on our preliminary data, PCA reinnervation and pacing offer promise for amelioration of respiratory compromise after paradoxical adduction in bilateral vocal fold impairment.
Broniatowski
Michael
M
Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. mbron@prodigy.net
Grundfest-Broniatowski
Sharon
S
Hadley
Aaron J
AJ
Shah
Nemath S
NS
Barbu
Anca M
AM
Phillipbar
Sue Ann
SA
Strohl
Kingman P
KP
Tucker
Harvey M
HM
Tyler
Dustin J
DJ
D006801:Humans; D007821:Laryngeal Muscles / Q000294:innervation*; D007828:Laryngoscopy; D012143:Respiratory Physiological Phenomena; D012135:Respiratory Sounds / Q000503:physiopathology; D013147:Spirometry; D046608:Synkinesis / Q000503:physiopathology; D014826:Vocal Cord Paralysis / Q000503:physiopathology* / Q000601:surgery*