title: Is screening for renal anomalies warranted in neonates with isolated single umbilical artery?
abstract: OBJECTIVE
  To determine the prevalence of renal anomalies in patients with an isolated single umbilical artery (SUA).
  
  
  METHODS
  We performed a retrospective study of all renal ultrasound examinations assessed at our centre between January 1998 and December 2008 in neonates with SUA with or without associated anomalies.
  
  
  RESULTS
  Renal ultrasound examination was performed in 65 neonates with SUA (57 neonates with isolated SUA and 8 neonates with nonisolated SUA). The prevalence of renal anomalies in the group with and without isolated SUA was 2% (1/57) and 38% (3/8), respectively. Only one patient with isolated SUA had a mild renal abnormality without clinical consequences.
  
  
  CONCLUSIONS
  The prevalence of renal anomalies in neonates with isolated SUA is low. We suggest that routine ultrasound screening for renal anomalies is not warranted in neonates with isolated SUA.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Leiden University Medical Centre, NL-2300 RC Leiden, The Netherlands.
authors.forename: M L
authors.initials: ML
authors.lastname: de Boom
authors.forename: J E
authors.initials: JE
authors.lastname: Kist-van Holthe
authors.forename: A
authors.initials: A
authors.lastname: Sramek
authors.forename: S W J
authors.initials: SW
authors.lastname: Lardenoye
authors.forename: F J
authors.initials: FJ
authors.lastname: Walther
authors.forename: E
authors.initials: E
authors.lastname: Lopriore
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000453:epidemiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000151:congenital / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D008297:Male; D015997:Neonatal Screening / Q000706:statistics & numerical data*; D015995:Prevalence; D012189:Retrospective Studies; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000002:abnormalities*; D014551:Urinary Tract / Q000002:abnormalities / Q000000981:diagnostic imaging