title: [Growth hormone and IGF-1 as doping agents in competitive sport].
abstract: Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, there is some evidences for many adverse effects in athletes using this form of doping. Blood tests to detect growth hormone abuse are available since several years. Surprisingly, no one has been proven to use illegal doping agents influencing GH/IGF-1 axis.
authors.affiliation: Zaklad Medycyny Sportu i Zywienia AWF, Wrocław. pjozkow@wp.pl
authors.forename: Paweł
authors.initials: P
authors.lastname: Jóźków
authors.forename: Marek
authors.initials: M
authors.lastname: Medraś
mesh_terms: D054874:Athletic Performance; D004300:Doping in Sports / Q000379:methods; D019382:Human Growth Hormone / Q000008:administration & dosage* / Q000097:blood; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000008:administration & dosage* / Q000009:adverse effects; D053580:Muscle Strength / Q000187:drug effects; D015813:Substance Abuse Detection / Q000379:methods*
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I