[Phenolic compounds from Galium aparine var. tenerum].
OBJECTIVE
To study the compounds from the whole plant of Galium aparine var. tenerum.


METHODS
The various column chromatographic techniques were applied to isolate the chemical constituents. MS, NMR and 2D-NMR spectroscopic techniques were uesd to identify chemical structures.


RESULTS
Six compounds were isolated from the EtOAc-soluble part of the 95% ethanol extract of the plant, and their chemical structures were identified as 1-(4-hydroxyphenyl)-ethanone (1), vanillic acid (2), 3,4-dihydroxybenzoic acid (3), p-hydroxycinnamic acid (4), gallic acid (5), 4-hydroxytruxillic acid (6).


CONCLUSIONS
The NMR data of compound 6 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMQC and HMBC spectra. This was the first time to report isolation of the compound 6 from natural product. The compounds 1-5 was isolated from the genus Galium for the first time.
Yang
Juan
J
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China. linyj401@tom.com
Cai
Xiaomei
X
Mu
Shuzhen
S
Yang
Xiaosheng
X
D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D032061:Galium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification
D004365:Drugs, Chinese Herbal; D010636:Phenols