title: Respiratory epithelial adenomatoid hamartoma in a dog.
abstract: A 6-month-old, intact, male Weimaraner dog presented to the veterinary teaching hospital for bilateral mucopurulent ocular and nasal discharge that began at approximately 10 weeks of age. A computed tomography scan showed an expansile soft-tissue mass involving both frontal sinuses, the ethmoid regions, and nasal cavities with lysis of the maxillary turbinates and hyperostosis of the walls of the frontal sinus. The dog was euthanized after complications during a trephination and biopsy procedure. At necropsy, a large, tan, papillary, gelatinous mass filled the entire nasal cavity and frontal sinus. The mass was composed of large fronds of loose fibrovascular stroma covered by a single layer of pseudostratified, columnar, ciliated epithelium and intermixed goblet cells. The cells occasionally formed glandular structures that were continuous with the surface epithelium. The mass was diagnosed as a respiratory epithelial adenomatoid hamartoma based on the morphologic appearance.
authors.affiliation: Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA. tleroith@vt.edu
authors.forename: Tanya
authors.initials: T
authors.lastname: Leroith
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Binder
authors.forename: A Heather
authors.initials: AH
authors.lastname: Graham
authors.forename: Robert B
authors.initials: RB
authors.lastname: Duncan
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D004285:Dogs; D004847:Epithelial Cells / Q000000981:diagnostic imaging / Q000473:pathology; D005065:Euthanasia; D020397:Goblet Cells / Q000000981:diagnostic imaging / Q000473:pathology; D006222:Hamartoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D017154:Stromal Cells / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed