title: Isohalitulin and haliclorensins B and C, three marine alkaloids from Haliclona tulearensis.
abstract: Three new alkaloids, designated isohalitulin (4), haliclorensin B (5), and haliclorensin C (6), were isolated from two specimens of the Madagascan sponge Haliclona tulearensis, collected at two locations in Salary Bay, north of Tulear. Their structures were elucidated by extensive spectroscopic means. Alkaloids 4-6 exhibited mild toxicity in the brine shrimp test.
authors.affiliation: School of Chemistry, Tel-Aviv University, Ramat Aviv, 69978, Israel.
authors.forename: Hagit
authors.initials: H
authors.lastname: Sorek
authors.forename: Amira
authors.initials: A
authors.lastname: Rudi
authors.forename: Maurice
authors.initials: M
authors.lastname: Aknin
authors.forename: Emile M
authors.initials: EM
authors.lastname: Gaydou
authors.forename: Yoel
authors.initials: Y
authors.lastname: Kashman
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D001156:Artemia / Q000187:drug effects; D047129:Haliclona / Q000737:chemistry*; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000470:Alkaloids; C484766:haliclorensin; C548931:haliclorensin B; C548932:haliclorensin C; C548930:isohalitulin