title: Relationship between cigarette use and mood/anxiety disorders among pregnant methadone-maintained patients.
abstract: This study investigates the association between cigarette use and current mood/anxiety disorders among pregnant opioid-dependent patients. Pregnant methadone-maintained women (N = 122) completed the Addiction Severity Index and Structured Clinical Interview for DSM-IV. Participants were categorized based on past 30 days cigarette use: no (n = 15) and any smoking (n = 107); this latter group was then subdivided into light (one to ten cigarettes/day; n = 55), and heavy smokers (11+ cigarettes/day; n = 52). Any smoking was significantly associated with any current mood/anxiety disorder (p < 0.001), any current mood disorder (p = 0.007), and any current anxiety disorder (p < 0.001). No significant association was found between specific level of cigarette use and mood/anxiety disorders. This association between smoking and psychiatric disorders has implications for the mental and physical health of methadone-maintained women and their children, and may contribute to the understanding of the physiological mechanisms underlying smoking and nicotine dependence.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. mchisol1@jhmi.edu
authors.forename: Margaret S
authors.initials: MS
authors.lastname: Chisolm
authors.forename: Michelle
authors.initials: M
authors.lastname: Tuten
authors.forename: Emily C
authors.initials: EC
authors.lastname: Brigham
authors.forename: Eric C
authors.initials: EC
authors.lastname: Strain
authors.forename: Hendrée E
authors.initials: HE
authors.lastname: Jones
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D019964:Mood Disorders / Q000150:complications*; D009292:Narcotic Antagonists / Q000627:therapeutic use; D009293:Opioid-Related Disorders / Q000150:complications* / Q000534:rehabilitation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D012907:Smoking / Q000523:psychology*
chemical_list: D009292:Narcotic Antagonists; D008691:Methadone