title: Detrusor underactivity: To tone or not to tone the bladder?
abstract: OBJECTIVE
  The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity.
  
  
  METHODS
  We searched all relevant data from Medline and peer-reviewed journals available online on the use of bethanechol in patients with detrusor underactivity.
  
  
  RESULTS
  Most reports that suggest a therapeutic clinical benefit with use of bethanechol have all been anecdotal reports and there is no definite clinical evidence available till date to support its clinical usefulness.
  
  
  CONCLUSIONS
  The current available data have shown to offer no definite benefit with the use of parasympathomimetic agents in patients with DU. One of the meta-analysis has shown bethanechol to be ineffective in promoting bladder emptying.
authors.affiliation: Department of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Sriram
authors.initials: S
authors.lastname: Krishnamoorthy
authors.forename: Nitin S
authors.initials: NS
authors.lastname: Kekre