title: Homocysteine and cerebrovascular accidents.
abstract: Hyperhomocysteinaemia is rapidly emerging as an important risk factor for coronary artery disease, possibly because of its propensity to accelerate atherosclerosis. Whether it is also a risk factor for cerebrovascular accidents (CVA) is a matter of debate till now, as there are conflicting results of the various prospective studies. The present study was performed to correlate the levels of plasma homocysteine levels with that of ischaemic and haemorrhagic CVA. Forty-two cases of CVA were randomly selected over a period of one year, and their risk factors were assessed. It was observed that serum homocysteine levels were significantly raised in those with intracerebral infarcts when compared to those with intracerebral haemorrhage, although homocysteine levels didn't prove to be prognostically significant.
authors.affiliation: Department of Medicine, NRS Medical College, Kolkata 700014.
authors.forename: Saikat
authors.initials: S
authors.lastname: Datta
authors.forename: Salil K
authors.initials: SK
authors.lastname: Pal
authors.forename: Hirak
authors.initials: H
authors.lastname: Mazumdar
authors.forename: Biswanath
authors.initials: B
authors.lastname: Bhandari
authors.forename: Sharmistha
authors.initials: S
authors.lastname: Bhattacherjee
authors.forename: Sudipta
authors.initials: S
authors.lastname: Pandit
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications*; D015994:Incidence; D049449:Luminescence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D020521:Stroke / Q000097:blood* / Q000453:epidemiology / Q000209:etiology