title: Improved prognosis for localized malignant lymphomas of the head and neck.
abstract: CONCLUSIONS
  In this study we found localized malignant lymphomas of the head and neck to be highly treatable and to have a significantly improved prognosis with recent treatment methods. The head and neck surgeon should keep in mind that the prognosis, especially for diffuse large B-cell lymphoma, has improved if the patient receives the optimal treatment.
  
  
  OBJECTIVE
  The purpose of this study was to ascertain the current prognosis of localized malignant lymphoma of the head and neck given recent advancements in treatment and diagnostic features, as well as adding histological subtypes to the literature according to the 2001 classification.
  
  
  METHODS
  We present a retrospective study including a cohort of 100 consecutive patients who had localized malignant lymphoma within the head and neck region diagnosed at a single centre from 2000 to 2007.
  
  
  RESULTS
  The histology was revised according to the WHO classification and showed 58% with diffuse large B-cell lymphoma. The estimated 5-year overall survival rate was 83%, which should be seen in contrast to survival rates of 40-70% 25 years ago.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. kasperaanaes@hotmail.com
authors.forename: Kasper
authors.initials: K
authors.lastname: Aanaes
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Kristensen
authors.forename: Elisabeth M
authors.initials: EM
authors.lastname: Ralfkiaer
authors.forename: Christian
authors.initials: C
authors.lastname: von Buchwald
authors.forename: Lena
authors.initials: L
authors.lastname: Specht
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult