Magnetic resonance imaging and clinical findings in a miniature Schnauzer with hypodipsic hypernatremia.
A 6-month-old miniature Schnauzer presented with hypernatremia and clinical signs of vomiting, diarrhea, inappetence, and lethargy. The dog did not consume water on its own. Hypernatremia and the related clinical signs were resolved by fluid administration. Endocrinological investigations and urinalysis excluded the possibility of diabetes insipidus and hyperaldosteronism. Therefore, the dog was diagnosed with hypodipsic hypernatremia. Magnetic resonance imaging revealed dysgenesis of the corpus callosum and other forebrain structures. On the basis of these findings, congenital brain malformation associated with failure of the osmoreceptor system was suspected.
Shimokawa Miyama
Takako
T
Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
Iwamoto
Emiko
E
Umeki
Saori
S
Nakaichi
Munekazu
M
Okuda
Masaru
M
Mizuno
Takuya
T
D000818:Animals; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000151:congenital / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004326:Drinking / Q000502:physiology*; D005260:Female; D006955:Hypernatremia / Q000151:congenital / Q000473:pathology / Q000662:veterinary*; D008279:Magnetic Resonance Imaging / Q000662:veterinary*