title: Studies on the Bohr Effect of Sheep Hemoglobin.
abstract: A simple method is described for the measurement of pH changes in hemoglobin solutions on oxygenation and reduction. Data are presented establishing the absence of a Bohr effect in p-chloromercuribenzoate [PCMB] treated hemoglobin. The influence of a number of sulfhydryl inhibitors on the Bohr effect of a hemoglobin solution is reported and an interpretation based on steric factors in the protein is proposed.
authors.affiliation: Departments of Biochemistry and Physiology, Yale University School of Medicine, New Haven.
authors.forename: D G
authors.initials: DG
authors.lastname: Smyth
authors.forename: F C
authors.initials: FC
authors.lastname: Battaglia
authors.forename: G
authors.initials: G
authors.lastname: Meschia