Lichenoid drug eruption.
A 78-year-old man presented with an eight-month history of folliculocentric, pink, hyperkeratotic papules and plaques with thick white scale that involved the entire body, with confluence on the buttocks and genitalia. A biopsy specimen demonstrated superficial and focal, mild perivascular and perifollicular, band-like lymphocytic infiltrate and eosinophils. There were lymphocytes extending to the dermo-epidermal junction with vacuolar changes. A diagnosis of lichenoid drug eruption secondary to a proton-pump inhibitor was made. To the best of our knowledge, only one other case of lichenoid drug eruption secondary to a proton-pump inhibitor has been reported.
Brauer
Jeremy
J
Department of Dermatology, New York University, USA.
Votava
Henry J
HJ
Meehan
Shane
S
Soter
Nicholas A
NA
D000368:Aged; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D006801:Humans; D017512:Lichenoid Eruptions / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D009853:Omeprazole / Q000009:adverse effects*; D054328:Proton Pump Inhibitors / Q000009:adverse effects*
D054328:Proton Pump Inhibitors; D009853:Omeprazole