Functional genes and proteins of Clonorchis sinensis.
During the past several decades, researches on parasite genetics have progressed from biochemical and serodiagnostic studies to protein chemistry, molecular biology, and functional gene studies. Nowadays, bioinformatics, genomics, and proteomics approaches are being applied by Korean parasitology researchers. As for Clonorchis sinensis, investigations have been carried out to identify its functional genes using forward and reverse genetic approaches and to characterize the biochemical and biological properties of its gene products. The authors review the proteins of cloned genes, which include antigenic proteins, physiologic and metabolic enzymes, and the gene expression profile of Clonorchis sinensis.
Kim
Tae Im
TI
Department of Medical Environmental Biology and Research Center for Biomolecules and Biosystems, Chung-Ang University College of Medicine, Seoul 156-756, Korea.
Na
Byoung-Kuk
BK
Hong
Sung-Jong
SJ
D000818:Animals; D003003:Clonorchiasis / Q000469:parasitology; D003004:Clonorchis sinensis / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism*; D005786:Gene Expression Regulation; D015801:Helminth Proteins / Q000235:genetics* / Q000378:metabolism*; D006801:Humans
D015801:Helminth Proteins