title: Perioral abscess associated with isotretinoin.
abstract: Severe scarring acne is frequently treated with isotretinoin. Patients treated with this drug may expect some of the more common complications including mucositis. Less common complications may also occur in a small number of patients. While undergoing treatment, patients may become colonized with Staphylococcus bacteria. However, the incidence of perioral abscess formation in patients taking isotretinoin is not commonly reported and the onset of this adverse event may masquerade as angioedema or severe mucositis.This article presents a case of a significant perioral abscess and discuss the need for prompt recognition as well as treatment of the infection.The case reported is unique due to the extent and severity of the abscess.
authors.affiliation: University of Miami, Department of Dermatology, Miami, FL, USA. Kenbeer@aol.com
authors.forename: Kenneth
authors.initials: K
authors.lastname: Beer
authors.forename: Hillary
authors.initials: H
authors.lastname: Oakley
authors.forename: Jill
authors.initials: J
authors.lastname: Waibel
mesh_terms: D000038:Abscess / Q000139:chemically induced* / Q000188:drug therapy / Q000382:microbiology; D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002921:Cicatrix / Q000188:drug therapy / Q000209:etiology; D003879:Dermatologic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D008047:Lip Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D012720:Severity of Illness Index; D013203:Staphylococcal Infections / Q000139:chemically induced / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D015474:Isotretinoin