Activity of antioxidant enzymes in the wound in patients with deep burns.
Analysis of wound discharge in children with deep burns over 3 weeks after the injury revealed gradual increase in catalase activity. The increase in activities of myeloperoxidase, glutathione-S-transferase, and catalase was maximum in patients with the most severe burns. Local complications were observed during the period of maximum myeloperoxidase activity, while the beginning of epithelialization was associated with its reduction. Analysis of wound impressions confirms long-term persistence of neutrophils in the wound.
Mikhal'chik
E V
EV
Russian State Medical University, Moscow, Russia. lemik2007@yandex.ru
Piterskaya
J A
JA
Lipatova
V A
VA
Pen'kov
L Yu
LY
Ibragimova
G A
GA
Korkina
L G
LG
D000293:Adolescent; D000975:Antioxidants / Q000378:metabolism*; D002056:Burns / Q000201:enzymology* / Q000503:physiopathology; D002374:Catalase / Q000378:metabolism*; D002648:Child; D005982:Glutathione Transferase / Q000378:metabolism*; D006801:Humans; D009504:Neutrophils / Q000378:metabolism / Q000502:physiology; D009195:Peroxidase / Q000378:metabolism*
D000975:Antioxidants; D002374:Catalase; D009195:Peroxidase; D005982:Glutathione Transferase