[An operated case of retroperitoneal venous hemangioma complicated with Kasabach-Merritt syndrome which was well controlled by danaparoid sodium].
A 32-year-old woman was admitted with intermittent rectal bleeding with disseminated intravascular coagulation (DIC)-like coagulopathy. CT and MRI revealed a retroperitoneal tumor, and we diagnosed giant retroperitoneal hemangioma complicated with Kasabach-Merritt syndrome, following blood pool scintigraphy. Corticosteroid and interferon-alpha were not effective, and gabexate mesilate was also ineffective for coagulopathy. Immediately after receiving danaparoid sodium, she recovered from DIC. We performed tumor resection successfully, and she had no symptoms of coagulopathy thereafter.
Moriguchi
Aya
A
Department of Medicine, Osaka Koseinenkin Hospital.
Iwahashi
Kiyoshi
K
Onishi
Yoshiki
Y
Kita
Hisaaki
H
Nishio
Akira
A
Kanno
Tomoyo
T
Matsuura
Tamiko
T
Ikezawa
Kenji
K
Ono
Akiko
A
Mizuno
Tatsunori
T
Chiba
Miho
M
Maeda
Kosaku
K
Aketa
Hiroshi
H
Naito
Masafumi
M
Michida
Tomoki
T
Katayama
Kazuhiro
K
Yamasaki
Yoshio
Y
Kasugai
Tsutomu
T
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D002809:Chondroitin Sulfates / Q000627:therapeutic use*; D003871:Dermatan Sulfate / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006391:Hemangioma / Q000150:complications* / Q000601:surgery; D006497:Heparan Sulfate / Q000627:therapeutic use*; D006801:Humans; D012186:Retroperitoneal Neoplasms / Q000150:complications* / Q000601:surgery
D000925:Anticoagulants; D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D006497:Heparan Sulfate; C035838:danaparoid