title: [Study on fingerprint of Maodongqing injection by HPLC].
abstract: OBJECTIVE
  To establish the fingerprint of Maodongqing injection by HPLC.
  
  
  METHODS
  The column of ODS-2 Hypersil C18 (4.6 mm x 200 mm, 5 microm) was used. The mobile phase consisted of acetonitrile-0.05% phosphoric acid with gradient elution. The flow rate was 1 mL/min, the column temperature was 30 degrees C, and the detection wavelength was 325 nm.
  
  
  RESULTS
  The fingerprint of Maodongqing injection was established, and 8 samples of different batches of Maodongqing injection were detected. Thirteen peaks in the chromatogram were marked by "Similarity Evaluation System for Chromatographic Fingerprints of Traditional Chinese Medicine (Version 2004 A)". There was a high similarity and each chromatographic peak was obtained with good separation and correlation according to the technical requirements of the fingerprints of Chinese traditional medicine.
  
  
  CONCLUSIONS
  This method is accurate, reliable and provides a scientific basis for controlling the quality of Maodongqing injection.
authors.affiliation: Guangdong Institute for Drug Control, Guangzhou 510180, China. laishan_77@163.com
authors.forename: Shan
authors.initials: S
authors.lastname: Lai
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Yang
authors.forename: Guo-Deng
authors.initials: GD
authors.lastname: Ou
authors.forename: Yong-Xue
authors.initials: YX
authors.lastname: Li
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D030017:Ilex / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D015203:Reproducibility of Results
chemical_list: D004365:Drugs, Chinese Herbal