Synthesis of alpha-cyanocinnamaldehydes from acrylonitrile and benzaldehydes catalyzed by Pd(OAc)(2)/HPMoV/FeCl(3)/O(2) system.
A facile direct synthesis of (E)-alpha-cyanocinnamaldehydes from acrylonitrile and benzaldehydes is successfully achieved in a mixed solvent of EtOH/AcOH by Pd(OAc)(2)/HPMoV/FeCl(3)/O(2) catalyst system. The reaction was found to proceed via the cross-aldol condensation of diethyl acetal derived from acrylonitrile with aldehydes.
Maeda
Sayuki
S
Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering and High Technology Research Center, Kansai University, Suita, Osaka 564-8680, Japan.
Horikawa
Norihide
N
Obora
Yasushi
Y
Ishii
Yasutaka
Y
D000085:Acetates / Q000737:chemistry*; D000171:Acrolein / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000181:Acrylonitrile / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014639:Vanadium / Q000737:chemistry*
D000085:Acetates; D001547:Benzaldehydes; D005290:Ferric Compounds; D009942:Organometallic Compounds; D014639:Vanadium; C516071:palladium(II) acetate; D000171:Acrolein; D008982:Molybdenum; D000181:Acrylonitrile; C012843:cinnamaldehyde