title: Free vascularized fibular grafting in combination with a locking plate for the reconstruction of a large tibial defect secondary to osteomyelitis in a child: a case report and literature review.
abstract: Although a large skeletal defect secondary to osteomyelitis in children is not an uncommon problem, there are no descriptions of the management of such a defect with a free vascularized fibular graft in combination with a locking plate. We performed such a technique, after radical debridement and systemic antibiotic treatment, on a 13-year-old boy suffering from a large 10 cm tibial defect secondary to osteomyelitis. Primary union of the graft was achieved at 6 months. No recurrence of osteomyelitis occurred in the 29-month follow-up period, and limb salvage and eradication of the infection were achieved successfully.
authors.affiliation: Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Wei-Tao
authors.initials: WT
authors.lastname: Jia
authors.forename: Chang-Qing
authors.initials: CQ
authors.lastname: Zhang
authors.forename: Jia-Gen
authors.initials: JG
authors.lastname: Sheng
authors.forename: Dong-Xu
authors.initials: DX
authors.lastname: Jin
authors.forename: Xiang-Guo
authors.initials: XG
authors.lastname: Cheng
authors.forename: Sheng-Bao
authors.initials: SB
authors.lastname: Chen
authors.forename: Bing-Fang
authors.initials: BF
authors.lastname: Zeng
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001860:Bone Plates; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D002444:Cefuroxime / Q000627:therapeutic use; D003646:Debridement; D005360:Fibula / Q000098:blood supply / Q000637:transplantation*; D006801:Humans; D023821:Limb Salvage / Q000379:methods*; D008297:Male; D016348:Osseointegration; D010019:Osteomyelitis / Q000150:complications / Q000473:pathology / Q000628:therapy*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D002444:Cefuroxime