title: Localized multiple glomangiomas on the foot.
abstract: We report a 15-year-old Japanese male with multiple, soft, blue and painless nodules on the left foot. The lesions had developed when the boy was 3 years old, and had enlarged gradually thereafter. None of his family members had any similar eruptions. All the lesions were resected under local anesthesia. Histological examination revealed cystically dilated spaces lined by endothelial cells and a few outer layers of glomus cells in the dermis and fat tissue. Immunohistochemistry demonstrated that the tumor cells were positive for alpha-smooth muscle actin. We diagnosed this case as localized multiple glomangioma. Multiple glomus tumors are much less common than solitary ones, and localized multiple glomus tumors are extremely rare. Because the clinical differential diagnosis of multiple glomangiomas includes common venous malformation, particularly blue rubber bleb nevus syndrome, histopathological studies should be performed.
authors.affiliation: Miyamoto Dermatological Office, School of Medicine, Yokohama City University, Isogo-ku, Yokohama, Japan. brb60130@nifty.com
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miyamoto
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Wada
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D005528:Foot / Q000473:pathology*; D005918:Glomus Tumor / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome