[Teratogenic risk of low level ionizing radiation. Congenital heart disease in infant].
Congenital heart diseases--the most prevalent and fatal birth defects worldwide--result from a combination of genetic predisposition and environmental factors. Currently, there is a growing body of epidemiological literature on parental and occupational prenatal risk factors. We report a case of a 4-months-old infant whose mother was professionally exposed to the cardiovascular catheterization laboratory during the first 4 weeks of pregnancy. The total radiation dose recorded by dosimeters under apron was 4220 microSiviert equivalent to 210 chest X-rays, suggesting the hypothesis of maternal ionising radiation induced-teratogenic effect.
Cresci
Monica
M
Unità di Ricerca Genetica, Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa.
Foffa
Ilenia
I
Ait-Ali
Lamia
L
Andreassi
Maria Grazia
MG
D000016:Abnormalities, Radiation-Induced / Q000209:etiology*; D005260:Female; D006330:Heart Defects, Congenital / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D018811:Maternal Exposure / Q000009:adverse effects; D016273:Occupational Exposure / Q000009:adverse effects; D012307:Risk Factors