title: [Research progress on mechanism of delaying senility of Chinese materia medica in recent years].
abstract: Recently investigating mechanisms on delaying aging of traditional Chinese medicine (TCM) and discovering high effective related medicines have been become hot spot and have achieved some progress. This review comprehensively analyzed the mechanism of TCM on delaying senility in recent years. The modern researches have demonstrated that Chinese materia medica and compound formulas can retard aging process by anti-oxidant activity of free radical, modulating metabolism of neuroendocrine, balancing immunological function, prolonging telomere length and promoting telomerase activity in cells, anti-DNA damage of cells, and controlling expression of gene and protein involved in cell proliferation.
authors.affiliation: Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Huili
authors.initials: H
authors.lastname: Gao
authors.forename: Danqiao
authors.initials: D
authors.lastname: Wang
mesh_terms: D000375:Aging / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D000818:Animals; D004358:Drug Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D008419:Materia Medica / Q000737:chemistry*; D008516:Medicine, Chinese Traditional
chemical_list: D004365:Drugs, Chinese Herbal; D008419:Materia Medica