title: Permanent central diabetes insipidus after mild traumatic brain injury.
abstract: OBJECTIVE
  The patients in the permanent diabetes insipidus (DI) group are more likely to have more severe TBI, which is defined by a post-resuscitational and pre-sedational Glasgow Coma Scale (GCS) score of 8/15 or less. This study presents a case of permanent, central DI following mild traumatic brain injury with post-resuscitation GCS 13/15.
  
  
  METHODS
  A 17-year-old boy suffered from mild brain injury and experienced permanent DI without any anatomical changes on image in the early stage of traumatic brain injury. However, 1 year later, magnetic resonance imaging (MRI) of the brain in this patient has revealed some sequel of contusion. Moreover, the patient still has DI after treatment with diamino-8-D-arginine vasopressin (DDAVP).
  
  
  CONCLUSIONS
  This patient had a rare clinical presentation of permanent, central DI, following a mild traumatic brain injury. Identification of head trauma as the aetiology of hypopituitarism may be overlooked if there is a long delay in onset after trauma. Since anterior hypopituitarism can develop decades after the episode of head trauma, monitoring for endocrine dysfunction during follow-up of these patients is important.
authors.affiliation: Department of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, Taiwan, PR China.
authors.forename: Yi-Chun
authors.initials: YC
authors.lastname: Chou
authors.forename: Tzu-Yuan
authors.initials: TY
authors.lastname: Wang
authors.forename: Pey-Yu
authors.initials: PY
authors.lastname: Yang
authors.forename: Nai-Hsin
authors.initials: NH
authors.lastname: Meng
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Chou
mesh_terms: D000063:Accidents, Traffic; D000293:Adolescent; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis; D020790:Diabetes Insipidus, Neurogenic / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D012720:Severity of Illness Index; D013997:Time Factors