title: Synthesis and biological evaluation of dehydroabietic acid derivatives.
abstract: A series of C18-oxygenated derivatives of dehydroabietic acid were synthesized from commercial abietic acid and evaluated for their cytotoxic, antimycotic, and antiviral activities.
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia, E-46100 Burjassot, Valencia, Spain. miguel.a.gonzalez@uv.es
authors.forename: Miguel A
authors.initials: MA
authors.lastname: González
authors.forename: David
authors.initials: D
authors.lastname: Pérez-Guaita
authors.forename: Julieth
authors.initials: J
authors.lastname: Correa-Royero
authors.forename: Bibiana
authors.initials: B
authors.lastname: Zapata
authors.forename: Lee
authors.initials: L
authors.lastname: Agudelo
authors.forename: Ana
authors.initials: A
authors.lastname: Mesa-Arango
authors.forename: Liliana
authors.initials: L
authors.lastname: Betancur-Galvis
mesh_terms: D045784:Abietanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D005658:Fungi / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D020128:Inhibitory Concentration 50; D008826:Microbial Sensitivity Tests
chemical_list: D045784:Abietanes; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D000998:Antiviral Agents; C013913:dehydroabietic acid; C023710:abietic acid