title: HIV, HCV, HBV and syphilis rate of positive donations among blood donations in Mali: lower rates among volunteer blood donors.
abstract: Good data on background seroprevalence of major transfusion transmitted infections is lacking in Mali. We gathered data on the rate of positive donations of human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV) and syphilis among blood donations in Mali for calendar year 2007. Donations with repeatedly reactive results on screening enzyme immunoassay (EIA) were considered to be seropositive. Rate of positive donations per blood unit collected was 2.6% for HIV, 3.3% for HCV, 13.9% for hepatitis B surface antigen (HBsAg) and 0.3% for syphilis. For HIV, HBsAg and syphilis, rate of positive donations was significantly (p<0.001) higher among donations from replacement donors than those from volunteer donors, while HCV rate of positive donations was similar in the two groups. Rate of positive donations was also significantly (p<0.0001) lower in blood units from regular than from first-time donors. These data reinforce WHO recommendations for increasing the number of regular, volunteer blood donors in Africa.
authors.affiliation: Centre national de transfusion sanguine, 24, rue Achkhabad, Quinzambougou, BP E-344, Bamako, Mali. amadoubdiarra@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Diarra
authors.forename: B
authors.initials: B
authors.lastname: Kouriba
authors.forename: M
authors.initials: M
authors.lastname: Baby
authors.forename: E
authors.initials: E
authors.lastname: Murphy
authors.forename: J-J
authors.initials: JJ
authors.lastname: Lefrere
mesh_terms: D001782:Blood Donors; D017848:Blood-Borne Pathogens; D015658:HIV Infections / Q000097:blood*; D006509:Hepatitis B / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000097:blood*; D006805:Human Experimentation / Q000706:statistics & numerical data; D006801:Humans; D008302:Mali / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D013587:Syphilis / Q000097:blood*
chemical_list: D006514:Hepatitis B Surface Antigens