Diagnostic and treatment algorithms of ulcerative colitis in Ukraine.
Questions concerning the diagnosis and treatment of ulcerative colitis (UC) in Ukraine are described. In recent years, there has been considerable progress in conservative therapy and new drugs have been developed that provide persistent remission of the inflammatory process after long-term application in many cases. The results of our own investigation on the efficiency of rebamipide in the complex treatment of UC patients are presented. Optimization of treatment with substitution of mesalazine in tablet or granule form, especially with an additional rebamipide prescription and a once-daily administration of budesonide, leads to an increased effectiveness of treatment and improvement of quality of life in UC patients. In the future, development of new approaches in the pharmacotherapy of UC will use medications as a basic therapy with the purpose of achieving high-quality and effective 'convalescence of mucous membrane', including cytoprotectors, bilious acids, endogenous substances, stabilization of membranes, antihypoxants and correction of microbiocenosis disorders.
Skrypnyk
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IN
Therapy Department, Postgraduate Education Faculty, Ukrainian Medical Stomatological Academy, Poltava, Ukraine. scrin69@yandex.ru
D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D014455:Ukraine / Q000453:epidemiology