title: [Macrovascular diabetic complications: clinical characteristics, diagnosis and management].
abstract: Diabetes mellitus (DM) is an independent risk factor for coronary heart disease, stroke, peripheral arterial disease and heart failure, which are the main causes of death in these patients. Moreover, patients with DM and cardiovascular disease have a worse prognosis than nondiabetics, present lower short-term survival, higher risk of recurrence of the disease and a worse response to the treatments proposed. In the last decades, diagnostic and therapeutic progress had already shown benefits concerning cardiovascular risk reduction in these patients, but their absolute mortality risk is still twice that of non-diabetic patients. Because of this, the adoption of intensive treatment, with strict cardiovascular risk factor control, is a priority. The present study presents the main clinical characteristics and also the practical approach for screening, diagnosis and treatment of patients with diabetic macrovascular disease.
authors.affiliation: Programa de Pós-graduação em Ciências Médicas: Endocrinologia e Metabologia, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Cristina
authors.initials: C
authors.lastname: Triches
authors.forename: Beatriz D'Agord
authors.initials: BD
authors.lastname: Schaan
authors.forename: Jorge Luiz
authors.initials: JL
authors.lastname: Gross
authors.forename: Mirela Jobim de
authors.initials: MJ
authors.lastname: Azevedo
mesh_terms: D003324:Coronary Artery Disease / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D003925:Diabetic Angiopathies / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis / Q000209:etiology / Q000628:therapy