title: Specific features of molecular postsynaptic excitation processes of different sensory modalities in edible snail neurons.
abstract: Stimulations of different sensory modalities result in selective activation of second messengers and genes controlled by them in defensive behavior command neurons (LPl-1 and RPl-1) in edible snail. Excitation induced by stimulation of chemoreceptors of snail head results in cAMP accumulation in command neurons and induction of associated transcriptional factors of immediate early gene C/EBP, whereas regulating mechanisms of another sensory input mediating excitation after tactile head stimulation, involve protein kinase C and associated transcriptional factor SRF. These findings reflect specific features of postsynaptic processes providing excitation of different sensory modalities converging to defensive behavior command neurons in edible snails.
authors.affiliation: P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow. nikitin.vp@mail.ru
authors.forename: V P
authors.initials: VP
authors.lastname: Nikitin
authors.forename: K V
authors.initials: KV
authors.lastname: Sudakov
authors.forename: V V
authors.initials: VV
authors.lastname: Sherstnev
mesh_terms: D000818:Animals; D022762:CCAAT-Enhancer-Binding Proteins / Q000378:metabolism / Q000502:physiology; D000242:Cyclic AMP / Q000378:metabolism / Q000502:physiology; D051766:Early Growth Response Protein 1 / Q000378:metabolism / Q000502:physiology; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology*; D006372:Helix, Snails / Q000378:metabolism / Q000502:physiology*; D008954:Models, Biological; D009473:Neuronal Plasticity / Q000502:physiology; D009474:Neurons / Q000378:metabolism / Q000502:physiology; D011493:Protein Kinase C / Q000378:metabolism / Q000502:physiology; D026362:Serum Response Factor / Q000378:metabolism / Q000502:physiology
chemical_list: D022762:CCAAT-Enhancer-Binding Proteins; D051766:Early Growth Response Protein 1; D026362:Serum Response Factor; D000242:Cyclic AMP; D011493:Protein Kinase C