title: [Delayed puberty].
abstract: Delayed puberty is defined in girls by the absence of breast development beyond 13 years old and in boys by the absence of testicular enlargement (< 4 ml) beyond 14 years old. Simple investigations lead to the diagnosis of central or peripheral hypogonadism and constitutional delay of puberty. In girls, delayed puberty is rare and often organic, and then Turner syndrome should be systematically suspected. In boys, delayed puberty is often constitutional and functional. Treatment is etiologic when possible, hormonal replacement therapy (oestrogen in girls and testosterone in boys) and psychological management.
authors.affiliation: Unité d'endocrinologie pédiatrique, maladies osseuses, génétique et gynécologie médicale, hôpital des enfants de Purpan, CHU de Toulouse, TSA, 31059 Toulouse cedex 9, France. edouard.t@chu-toulouse.fr
authors.forename: T
authors.initials: T
authors.lastname: Edouard
authors.forename: M
authors.initials: M
authors.lastname: Tauber
mesh_terms: D000293:Adolescent; D000365:Age Determination by Skeleton; D003937:Diagnosis, Differential; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D007713:Klinefelter Syndrome / Q000175:diagnosis / Q000628:therapy; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011379:Prognosis; D011628:Puberty, Delayed / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012016:Reference Values; D014424:Turner Syndrome / Q000175:diagnosis / Q000628:therapy
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone