Saucy-Marbet Rearrangements of Alkynyl Halides in the Synthesis of Highly Enantiomerically Enriched Allenyl Halides.
A stereospecific Saucy-Marbet rearrangement of alkynyl halides is described here. These rearrangements provide an entry to highly enantiomerically enriched allenyl bromides and chlorides through excellent chirality transfer and the reservation of optical integrity of alkynyl halides.
Tang
Yu
Y
Division of Pharmauetical Sciences and Department of Chemistry, 777 Highland Avenue, University of Wisconsin, Madison, WI 53705.
Shen
Lichun
L
Dellaria
Becky J
BJ
Hsung
Richard P
RP