THE SULFONIUM SALT OF MUSTARD GAS: BIS-beta-[BIS(beta-HYDROXYETHYL) SULFONIUM] ETHYLSULFIDE DICHLORIDE (H.2TDG).
1. The sulfonium salt H.2TDG is formed when H is mixed with even dilute solutions of TDG. Crystalline H.2TDG was isolated from such a reaction mixture. A simple method of preparation of this salt is outlined. 2. A material which differs from H.2TDG in that it hydrolyzes faster, is formed when H hydrolyzes in water. This material is probably H.1TDG but it was not isolated. Approximately 5 to 8 per cent of the original H is converted to this sulfonium salt. 3. The hydrolysis constant of M/100 H.2TDG has been determined at 20 degrees , 25.5 degrees , 37 degrees , 75 degrees , and 100 degrees C., a temperature coefficient, Q(10), of 3-4 was obtained. The effect of temperature is in agreement with that predicted by the Arrhenius equation. An activation energy of 26,000 calories was calculated.
Herriott
R M
RM
Laboratories of The Rockefeller Institute for Medical Research, Princeton, New Jersey.
D006868:Hydrolysis; D009151:Mustard Gas; D012965:Sodium Chloride; D013440:Sulfides
D013440:Sulfides; D012965:Sodium Chloride; D009151:Mustard Gas