title: [Study on the influence on the content of dehydrocavidine and total alkaloids in Corydalis saxicola by different drying methods].
abstract: OBJECTIVE
  To evaluate the influence of five different drying methods on the contents of dehydrocavidine, a main active constituent, and total alkaloids in Corydalis saxicola.
  
  
  METHODS
  The whole plant samples of C. saxicola were harvested at its florescence stage, and then immediately divided into four parts of root, stem, leaf, and inflorescence. Each part of sample was dried by the following five methods, drying in a sunshine, drying in a shade, oven-drying at 60 degrees C, vacuum-drying at room temperature and frozen vacuum-drying, respectively. Then the contents of dehydrocavidine and total alkaloids were determined by RP-HPLC and ultraviolet spectrophotometry.
  
  
  RESULTS
  The contents of dehydrocavidine and total alkaloids in all the four parts of the sample processed by drying in a shade were significantly higher than those in the samples processed by the other four drying mehods.
  
  
  CONCLUSIONS
  Different drying methods could significantly influence the contents of dehydrocavidine and total alkaloids in C. saxicola. The process of drying in a shade for a long time would be the best.
authors.affiliation: College of Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510080, China. Isswdm@mail.sysu.edu.cn
authors.forename: Dong-Mei
authors.initials: DM
authors.lastname: Wang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Tang
authors.forename: Zhi-Chao
authors.initials: ZC
authors.lastname: He
authors.forename: Xuan-Xuan
authors.initials: XX
authors.lastname: Cheng
authors.forename: Zhong-Fu
authors.initials: ZF
authors.lastname: Wei
authors.forename: De-Po
authors.initials: DP
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Jiang
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D001600:Berberine Alkaloids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D031311:Corydalis / Q000737:chemistry*; D003890:Desiccation / Q000379:methods*; D005612:Freeze Drying; D010598:Pharmacognosy; D035261:Plant Components, Aerial / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature
chemical_list: D000470:Alkaloids; D001600:Berberine Alkaloids; C011188:cavidine