Do we have to pay more attention to vitiligo patients? Peculiar histopathological features of primary cutaneous melanoma preceded by vitiligo.
Vitiligo is an acquired depigmenting skin disease characterized by the loss of functioning epidermal melanocytes. Vitiligo can be associated with an autoimmune disorder. An unusual and important aspect of vitiligo is its relationship to melanoma. We present herein a 34-year-old man who developed regional lymph node metastases of malignant melanoma 2 years after the diagnosis of vitiligo.
Onsun
Nahide
N
Department of Dermatology of Vakif Gureba Teaching and Research Hospital, Fatih, Istanbul, Turkey. Nahide.onsun@vakifgureba.gov.tr
Büyükbabani
Nesimi
N
Ummetoğlu
Omer
O
Cebeci
Filiz
F
D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis*; D001707:Biopsy, Needle; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000276:immunology / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D009361:Neoplasm Invasiveness / Q000473:pathology; D009362:Neoplasm Metastasis; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D014820:Vitiligo / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*