title: Spectrally tunable leakage-free gold nanocontainers.
abstract: Drug delivery with precise spatial and temporal control is of broad current interest in biology and medicine. Despite recent advances achieved by combining drugs or drug carriers with NIR light responsive plasmonic nanomaterials, existing technologies are not capable of preventing drug leakage or degradation. We report a new class of monodisperse gold nanocontainer that can stably encapsulate cargo molecules, yet is compact in size and tunable in spectral responses.
authors.affiliation: Department of Bioengineering, University of Washington, William H. Foege Building N530M, Seattle, Washington 98195, USA.
authors.forename: Yongdong
authors.initials: Y
authors.lastname: Jin
authors.forename: Xiaohu
authors.initials: X
authors.lastname: Gao
mesh_terms: D000327:Adsorption; D005452:Fluoresceins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D009841:Oligonucleotides / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D005452:Fluoresceins; D005456:Fluorescent Dyes; D008081:Liposomes; D009841:Oligonucleotides; C024098:6-carboxyfluorescein; D006046:Gold