title: Evaluation of novel epothilone analogues by means of a common pharmacophore and a QSAR pseudoreceptor model for taxanes and epothilones.
authors.affiliation: Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Alcide de Gasperi 2, 53100 Siena, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Forli
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Manetti
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Altmann
authors.forename: Maurizio
authors.initials: M
authors.lastname: Botta
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D034261:Epothilones / Q000737:chemistry* / Q000494:pharmacology; D017239:Paclitaxel / Q000737:chemistry / Q000494:pharmacology; D011485:Protein Binding; D021281:Quantitative Structure-Activity Relationship; D043823:Taxoids / Q000737:chemistry* / Q000494:pharmacology; D014404:Tubulin / Q000737:chemistry / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D034261:Epothilones; D043823:Taxoids; D014404:Tubulin; D017239:Paclitaxel; C093788:epothilone B