title: Alasmontamine A, A first tetrakis monoterpene indole alkaloid from Tabernaemontana elegans.
abstract: A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo 142-8501, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: Saori
authors.initials: S
authors.lastname: Miyama
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hosoya
authors.forename: Koichiro
authors.initials: K
authors.lastname: Koyama
authors.forename: Abdul
authors.initials: A
authors.lastname: Rahman
authors.forename: Idha
authors.initials: I
authors.lastname: Kusumawati
authors.forename: Noor Cholies
authors.initials: NC
authors.lastname: Zaini
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D046948:Secologanin Tryptamine Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D030014:Tabernaemontana / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D046948:Secologanin Tryptamine Alkaloids; C546676:alasmontamine A