title: Comparison of standard vs high-definition, wide-angle colonoscopy for polyp detection: a randomized controlled trial.
abstract: OBJECTIVE
  We sought to compare the performance of colonoscopy using a high-definition, wide-angle endoscope vs a standard colonoscope for the detection of polyps.
  
  
  METHODS
  A total of 390 patients were prospectively randomized into high-definition colonoscopy group (HD, n = 193) and standard colonoscopy group (SC, n = 197).
  
  
  RESULTS
  Analysis demonstrated that there were significant differences between the two groups, as far as the overall rate of polyps (SC, 1.31 ± 1.90; HD, 1.76 ± 2.31; P = 0.03) and the rate of small hyperplastic polyps (size < 5 mm; SC, 0.10 ± 0.36; HD, 0.25 ± 0.61; P = 0.003) were concerned. No significant differences between the two groups were observed, regarding large polyps (size ≥ 10 mm; SC, 0.39 ± 0.89; HD, 0.48 ± 0.80; P = 0.10), medium polyps (10 mm > size ≥ 5 mm; SC, 0.60 ± 1.46; HD, 0.58 ± 1.25; P = 0.31) and small polyps (size < 5 mm; SC, 0.32 ± 0.86; HD, 0.71 ± 1.65; P = 0.09). Similarly, no significant differences were demonstrated in the detection rate of adenomas and hyperplastic polyps, large adenomas, medium adenomas, small adenomas and large and medium hyperplastic polyps.
  
  
  CONCLUSIONS
  High-definition colonoscopy led to a significant increase in the polyp detection.
authors.affiliation: Department of Gastroenterology, Benizelion General Hospital, Heraklion, Crete, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Tribonias
authors.forename: A
authors.initials: A
authors.lastname: Theodoropoulou
authors.forename: K
authors.initials: K
authors.lastname: Konstantinidis
authors.forename: E
authors.initials: E
authors.lastname: Vardas
authors.forename: K
authors.initials: K
authors.lastname: Karmiris
authors.forename: N
authors.initials: N
authors.lastname: Chroniaris
authors.forename: G
authors.initials: G
authors.lastname: Chlouverakis
authors.forename: G A
authors.initials: GA
authors.lastname: Paspatis
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D000368:Aged; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003111:Colonic Polyps / Q000175:diagnosis* / Q000473:pathology; D020685:Colonoscopes; D003113:Colonoscopy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013997:Time Factors; D013996:Time and Motion Studies