title: Genomic tandem repeat analysis proves laboratory-acquired brucellosis in veterinary (camel) diagnostic laboratory in the United Arab Emirates.
abstract: We report a case of a 64-year-old veterinarian working in a state camel veterinary laboratory who was diagnosed with and treated for acute brucellosis with complicating epididymo-orchitis. Genomic tandem repeat analysis (MLVA-16) revealed identical Brucella strains in patient cultures and from different dromedary milk samples positive for Brucella melitensis, thereby confirming the diagnosis of a laboratory acquired infection. The case illustrates the high (airborne) infectivity of brucellosis in laboratory settings and the need to implement vigorous bio-safety measures in veterinary laboratories handling camel specimen diagnostic veterinary laboratory.
authors.affiliation: Medizinische Klinik, Bernhard-Nocht-Klinik für Tropenmedizin, Zentrum für Innere Medizin, Universitätsklinikum Hamburg Eppendorf, Germany. julianszw@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Schulze zur Wiesch
authors.forename: D
authors.initials: D
authors.lastname: Wichmann
authors.forename: I
authors.initials: I
authors.lastname: Sobottka
authors.forename: H
authors.initials: H
authors.lastname: Rohde
authors.forename: G
authors.initials: G
authors.lastname: Schmoock
authors.forename: R
authors.initials: R
authors.lastname: Wernery
authors.forename: S
authors.initials: S
authors.lastname: Schmiedel
authors.forename: G
authors.initials: G
authors.lastname: Dieter Burchard
authors.forename: F
authors.initials: F
authors.lastname: Melzer
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D002162:Camelus; D006801:Humans; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D020080:Tandem Repeat Sequences / Q000235:genetics*; D014479:United Arab Emirates / Q000453:epidemiology; D015047:Zoonoses / Q000453:epidemiology* / Q000635:transmission
chemical_list: D000900:Anti-Bacterial Agents