Familial furunculosis associated with community-acquired leukocidin-positive methicillin-susceptible Staphylococcus aureus ST152.
Panton-Valentine leukocidin (PVL) is associated with staphylococcal skin and pulmonary infections. Community dissemination of PVL-producing Staphylococcus aureus strains constitutes a public health concern. Family transmission and spread of community-acquired leukocidin-positive methicillin-susceptible S. aureus ST152 isolates associated with severe clinical symptoms are herein described. Remarkably, ST152 isolates usually are methicillin resistant.
Pérez-Roth
E
E
Unidad de Investigación, Hospital Universitario NS Candelaria, Ctra. del Rosario 100, 38010 Santa Cruz de Tenerife, Spain.
Alcoba-Flórez
J
J
López-Aguilar
C
C
Gutiérrez-González
I
I
Rivero-Pérez
B
B
Méndez-Alvarez
S
S
D000293:Adolescent; D000328:Adult; D001426:Bacterial Proteins / Q000096:biosynthesis; D015373:Bacterial Typing Techniques; D002648:Child; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D016172:DNA Fingerprinting; D005192:Family Health; D005667:Furunculosis / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D005838:Genotype; D006801:Humans; D007956:Leukocidins / Q000096:biosynthesis; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012150:Polymorphism, Restriction Fragment Length; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D037521:Virulence Factors / Q000096:biosynthesis
D001426:Bacterial Proteins; D007956:Leukocidins; D037521:Virulence Factors