title: Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions.
abstract: Bone defects represent a difficult problem for the clinician. They entail a sustained increase in hospitalization, risk of complications, and associated increase in expenses. This article discusses bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions.
authors.affiliation: Department of Orthopedic Trauma, Aachen University Medical Center, Pauwelsstr. 30, Aachen 52074, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Wiese
authors.forename: Hans C
authors.initials: HC
authors.lastname: Pape
mesh_terms: D001862:Bone Resorption / Q000209:etiology*; D001842:Bone and Bones / Q000293:injuries*; D005593:Fracture Fixation, Internal / Q000379:methods*; D005599:Fractures, Ununited / Q000150:complications / Q000601:surgery*; D006801:Humans; D010019:Osteomyelitis / Q000209:etiology* / Q000517:prevention & control; D011379:Prognosis; D015599:Trauma Severity Indices; D014947:Wounds and Injuries / Q000150:complications / Q000601:surgery*