title: Advances in absorbable biomaterials and nasal packing.
abstract: Absorbable biomaterials are commonly used after endoscopic sinus surgery, both for hemostatic and wound healing considerations. Although removable nasal packing is the traditional method of controlling ongoing bleeding and modulating wound healing, it is uncomfortable for patients and associated with several complications. Currently available absorbable agents frequently incite an inflammatory reaction and have been shown in animal and human trials to adversely affect the wound healing process. Newer agents offer distinct advantages because of their unique composition and rapid clearance profiles. The selection of packing material used in any given sinus procedure should be based on surgeon preference and the details of the specific case.
authors.affiliation: Department of Surgery-Otorhinolaryngology, Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, 28 Woodville Road, Woodville, Adelaide, SA 5011, Australia.
authors.forename: Rowan
authors.initials: R
authors.lastname: Valentine
authors.forename: Peter-John
authors.initials: PJ
authors.lastname: Wormald
authors.forename: Raj
authors.initials: R
authors.lastname: Sindwani
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use; D002483:Cellulose, Oxidized; D004195:Disease Models, Animal; D004724:Endoscopy; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006488:Hemostasis, Surgical / Q000379:methods / Q000639:trends; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D013517:Otorhinolaryngologic Surgical Procedures; D010256:Paranasal Sinuses / Q000601:surgery*; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D000267:Tissue Adhesions / Q000517:prevention & control; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D002483:Cellulose, Oxidized; C411004:FloSeal Matrix; D006490:Hemostatics; C013695:Surgicel