Gene therapy with vascular endothelial growth factors.
Therapeutic angiogenesis is a promising new concept for the treatment of myocardial and peripheral ischaemia. Members of the VEGF (vascular endothelial growth factor) family are among the most powerful modulators of angiogenesis. They regulate vascular growth and maintenance during embryogenesis and in adults. The present review summarizes the current status of therapeutic angiogenesis using VEGF, with special reference to preclinical studies.
Ylä-Herttuala
Seppo
S
Department of Medicine, AI Virtanen Institute, University of Kuopio, Kuopio, Finland. seppo.ylaherttuala@uku.fi
D000818:Animals; D015316:Genetic Therapy; D006439:Hemodynamics; D006801:Humans; D023421:Models, Animal; D018919:Neovascularization, Physiologic; D012039:Regional Blood Flow; D042442:Vascular Endothelial Growth Factors / Q000235:genetics / Q000627:therapeutic use
D042442:Vascular Endothelial Growth Factors