title: Fluorodeoxyglucose-positron-emission tomography imaging of head and neck squamous cell cancer.
abstract: The hybrid technique of PET/CT has significantly impacted the imaging and management of HNSCC since its introduction in 2001 and has become the technique of choice for imaging of this cancer. Diagnostic FDG-PET/CT is useful for identification of an unknown primary tumor, delineation of extent of primary tumor, detection of regional lymph node involvement even in a normal-sized node, detection of distant metastases and occasional synchronous primary tumor, assessment of therapy response, and long-term surveillance for recurrence and metastases. The role of PET/CT is evolving in radiation therapy planning. Combined diagnostic PET/CT provides the best anatomic and metabolic in vivo information for the comprehensive management of HNSCC.
authors.affiliation: Department of Radiology, Boston Medical Center and Boston University, Massachusetts 02118, USA. rathan.subramaniam@bmc.org
authors.forename: R M
authors.initials: RM
authors.lastname: Subramaniam
authors.forename: M
authors.initials: M
authors.lastname: Truong
authors.forename: P
authors.initials: P
authors.lastname: Peller
authors.forename: O
authors.initials: O
authors.lastname: Sakai
authors.forename: G
authors.initials: G
authors.lastname: Mercier
mesh_terms: D044963:Biopsy, Fine-Needle; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary / Q000628:therapy; D018450:Disease Progression; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D018365:Neoplasm, Residual / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging; D010039:Otorhinolaryngologic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary / Q000628:therapy; D049268:Positron-Emission Tomography; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden; D014463:Ultrasonography
chemical_list: D019788:Fluorodeoxyglucose F18