Effects of scalp acupuncture versus upper and lower limb acupuncture on signal activation of blood oxygen level dependent (BOLD) fMRI of the brain and somatosensory cortex.
OBJECTIVE
The objective of this article is to investigate brain activity of scalp acupuncture (SA) as compared to upper and lower limb acupuncture (ULLA) using functional magnetic resonance imaging (fMRI).


METHODS
Ten (10) healthy right-handed female volunteers aged 20-35 were divided into 2 groups: a SA group and an ULLA group. The SA group had needles inserted at the left Sishencong (HN1), GB18, GB9, TH20, and the ULLA group at the right LI1, LI10, LV3, ST36 for 20 minutes, respectively. Both groups had tactile stimulation in the order of the right LI1, LI10, LV3, ST36 before and after acupuncture for a block of 21 seconds repeated 3 times. The blood oxygen level dependent (BOLD) fMRI was used to observe the brain and somatosensory cortex signal activation.


RESULTS
We compared the signal activation before and after acupuncture needling, and the images showed signal activation after removing the acupuncture needles and the contralateral somatosensory association cortex, the postcentral gyrus, and the parietal lobe were more activated in the SA group. The right occipital lobe, the lingual gyrus, the visual association cortex, the right parahippocampal gyrus, the limbic lobe, the hippocampus, the left anterior lobe, the culmen, and the cerebellum were activated in the ULLA group.


CONCLUSIONS
We concluded that there were different signal activations of BOLD fMRI before and after SA versus ULLA, which can be thought to be caused by the sensitivity of acupoints and the different sensory receptors to acupuncture needling.
Park
Seong-Uk
SU
Department of Cardiovascular & Neurologic Disease (Stroke Center), East-West Neo Medical Center, College of Oriental Medicine, Kyunghee University, Seoul, Korea.
Shin
Ae-Sook
AS
Jahng
Geon-Ho
GH
Moon
Sang-Kwan
SK
Park
Jung-Mi
JM
D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D035002:Lower Extremity; D008279:Magnetic Resonance Imaging; D009339:Needles; D010100:Oxygen / Q000097:blood*; D012016:Reference Values; D012535:Scalp; D034941:Upper Extremity; D055815:Young Adult
D010100:Oxygen