One-pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogenation condition with supported gold nanoparticles.
One-pot sequences of hydrogenation/hydroamination to form indoles from (2-nitroaryl)alkynes and hydrogenation/reductive amination to form aniline derivatives from nitroarenes and aldehydes were catalyzed by Au nanoparticles supported on Fe(2)O(3). Nitro group selective hydrogenations and successive reactions were efficiently catalyzed under the conditions.
Yamane
Yoshihiro
Y
Department of Chemistry, Graduate School of Science, Kyushu University, Fukuoka 812-8581, Japan.
Liu
Xiaohao
X
Hamasaki
Akiyuki
A
Ishida
Tamao
T
Haruta
Masatake
M
Yokoyama
Takushi
T
Tokunaga
Makoto
M
D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006865:Hydrogenation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry*; D015394:Molecular Structure; D009578:Nitrobenzenes / Q000737:chemistry*; D010316:Particle Size; D013237:Stereoisomerism; D013499:Surface Properties
D000814:Aniline Compounds; D007211:Indoles; D009578:Nitrobenzenes; D006046:Gold; C023650:aniline