Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives.
The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.
Fülöp
F
F
Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary. fulop@pharm.u-szeged.hu
Szatmári
I
I
Vámos
E
E
Zádori
D
D
Toldi
J
J
Vécsei
L
L
D003920:Diabetes Mellitus / Q000188:drug therapy; D006801:Humans; D007511:Ischemia / Q000188:drug therapy; D007736:Kynurenic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D051437:Renal Insufficiency / Q000188:drug therapy; D012559:Schizophrenia / Q000188:drug therapy
D007736:Kynurenic Acid