title: HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.
abstract: HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.
authors.affiliation: Division of Viral Products, Center for Biologics Evaluation and Research, FDA, 8800 Rockville Pike, Bethesda, MD 20892, USA.
authors.forename: Surender
authors.initials: S
authors.lastname: Khurana
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Norris
authors.forename: Michael P
authors.initials: MP
authors.lastname: Busch
authors.forename: Barton F
authors.initials: BF
authors.lastname: Haynes
authors.forename: Susan
authors.initials: S
authors.lastname: Park
authors.forename: Pretty
authors.initials: P
authors.lastname: Sasono
authors.forename: Koleka
authors.initials: K
authors.lastname: Mlisana
authors.forename: Abdool Karim
authors.initials: AK
authors.lastname: Salim
authors.forename: Frederick M
authors.initials: FM
authors.lastname: Hecht
authors.forename: Joseph
authors.initials: J
authors.lastname: Mulenga
authors.forename: Elwyn
authors.initials: E
authors.lastname: Chomba
authors.forename: Eric
authors.initials: E
authors.lastname: Hunter
authors.forename: Susan
authors.initials: S
authors.lastname: Allen
authors.forename: George
authors.initials: G
authors.lastname: Nemo
authors.forename: Isaac R
authors.initials: IR
authors.lastname: Rodriguez-Chavez
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Margolick
authors.forename: Hana
authors.initials: H
authors.lastname: Golding
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D005260:Female; D015658:HIV Infections / Q000175:diagnosis*; D006679:HIV Seropositivity; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D008297:Male; D012680:Sensitivity and Specificity
chemical_list: D000914:Antibodies, Viral