title: Clinical applicability of a 1 450 nm diode laser as adjunctive treatment for refractory acne.
abstract: Acne is a multifactorial disease of the pilosebaceous units of the face and trunk, most commonly affecting young adolescents. Acne still represents the most common concern in dermatologic consultations and despite aggressive multi-treatment regimens, many patients demonstrate a poor response. A number of recent studies have evaluated the role of laser and light therapy in the treatment of acne vulgaris, with variable clinical outcomes. Among them, a 1450 nm diode laser has been shown to improve refractory acne in a clinical setting. The content of this manuscript draws upon current literature and will critically review the role of mid-infrared lasers as adjunctive therapy for acne.
authors.affiliation: Department of Dermatology, Charité University Medicine Berlin, Berlin, Germany. susanne.astner@charite.de
authors.forename: S
authors.initials: S
authors.lastname: Astner
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy / Q000532:radiotherapy*; D000293:Adolescent; D000328:Adult; D000818:Animals; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D054023:Lasers, Semiconductor / Q000009:adverse effects / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000009:adverse effects; D008297:Male; D011817:Rabbits; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D016032:Randomized Controlled Trials as Topic; D012627:Sebaceous Glands / Q000528:radiation effects; D012880:Skin Pigmentation; D016896:Treatment Outcome; D055815:Young Adult