title: ENFIN--A European network for integrative systems biology.
abstract: Integration of biological data of various types and the development of adapted bioinformatics tools represent critical objectives to enable research at the systems level. The European Network of Excellence ENFIN is engaged in developing an adapted infrastructure to connect databases, and platforms to enable both the generation of new bioinformatics tools and the experimental validation of computational predictions. With the aim of bridging the gap existing between standard wet laboratories and bioinformatics, the ENFIN Network runs integrative research projects to bring the latest computational techniques to bear directly on questions dedicated to systems biology in the wet laboratory environment. The Network maintains internally close collaboration between experimental and computational research, enabling a permanent cycling of experimental validation and improvement of computational prediction methods. The computational work includes the development of a database infrastructure (EnCORE), bioinformatics analysis methods and a novel platform for protein function analysis FuncNet.
authors.affiliation: EMBL - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom. pkahlem@ebi.ac.uk
authors.forename: Pascal
authors.initials: P
authors.lastname: Kahlem
authors.forename: Andrew
authors.initials: A
authors.lastname: Clegg
authors.forename: Florian
authors.initials: F
authors.lastname: Reisinger
authors.forename: Ioannis
authors.initials: I
authors.lastname: Xenarios
authors.forename: Henning
authors.initials: H
authors.lastname: Hermjakob
authors.forename: Christine
authors.initials: C
authors.lastname: Orengo
authors.forename: Ewan
authors.initials: E
authors.lastname: Birney
mesh_terms: D003195:Computer Communication Networks / Q000458:organization & administration*; D003299:Cooperative Behavior; D003628:Database Management Systems; D016208:Databases, Factual; D005060:Europe; D020407:Internet; D011506:Proteins / Q000502:physiology; D012106:Research; D049490:Systems Biology / Q000458:organization & administration*; D018511:Systems Integration
chemical_list: D011506:Proteins