title: Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue.
abstract: The authors describe a 9 month old female with recurrent atypical central neurocytoma and leptomeningeal spread treated with high dose chemotherapy, autologous stem cell rescue, and adjuvant therapy. She had a complete response to therapy and was disease free at 4 years of age until a recurrence 6 months later. The use of intensive chemotherapy followed by autologous stem cell rescue for atypical neurocytoma may be considered as an adjunct to surgical therapy in young patients with atypical neurocytoma not amenable to radiation therapy.
authors.affiliation: Department of Pediatric Hematology, Children's Hospital of Orange County, 455 S Main Street, Orange, CA 92868, USA. dbuchbinder@choc.org
authors.forename: David
authors.initials: D
authors.lastname: Buchbinder
authors.forename: Moise
authors.initials: M
authors.lastname: Danielpour
authors.forename: William H
authors.initials: WH
authors.lastname: Yong
authors.forename: Noriko
authors.initials: N
authors.lastname: Salamon
authors.forename: Joseph
authors.initials: J
authors.lastname: Lasky
mesh_terms: D001932:Brain Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D018306:Neurocytoma / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000379:methods