title: New-onset dissociative disorder after electroconvulsive therapy.
abstract: Electroconvulsive therapy (ECT) is an exceptionally effective treatment for a number of psychiatric conditions; however, a common adverse effect is temporary cognitive impairment, especially memory loss. The dissociative disorders also involve disturbances of memory, as well as consciousness and personal identity, but are rarely iatrogenic. We report a case in which dissociative symptoms developed after ECT. A 51-year-old woman with hypothyroidism, migraine headaches, bipolar disorder, and anorexia by history was admitted for worsening depression with suicidal ideation. After a course of 7 right-sided ECT treatments, she experienced remarkable personality change, claiming that it was 1976 and behaving as though she was 30 years younger. Neuropsychological tests were normal, and her memory and former personality spontaneously returned 2 weeks later. This case illustrates that such events may be seen in patients with certain psychiatric profiles, and further studies are needed to determine the risk factors for the occurrence of dissociative episodes after ECT.
authors.affiliation: Adult Outpatient Psychiatry Service, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, Cambridge, MA, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Zaidner
authors.forename: R Andrew
authors.initials: RA
authors.lastname: Sewell
authors.forename: Evan
authors.initials: E
authors.lastname: Murray
authors.forename: Allen
authors.initials: A
authors.lastname: Schiller
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Price
authors.forename: Miles G
authors.initials: MG
authors.lastname: Cunningham
mesh_terms: D001714:Bipolar Disorder / Q000628:therapy; D004213:Dissociative Disorders / Q000150:complications*; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008569:Memory Disorders / Q000150:complications; D008875:Middle Aged