title: Magnetic resonance imaging assessment of subchondral bone and soft tissues in knee osteoarthritis.
abstract: Knee osteoarthritis (OA) has to be considered a whole joint disease. Magnetic resonance imaging (MRI) allows superior assessment of all joint tissues that may be involved in OA, such as the subchondral bone, synovium, ligaments, and periarticular soft tissues. Reliable MRI-based scoring systems are available to assess and quantify these structures and associated pathology. Cross-sectional and longitudinal evaluation has enabled practitioners to understand their relevance in explaining pain and structural progression.
authors.affiliation: Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118, USA. michelcrema@gmail.com
authors.forename: Michel D
authors.initials: MD
authors.lastname: Crema
authors.forename: Frank W
authors.initials: FW
authors.lastname: Roemer
authors.forename: Monica D
authors.initials: MD
authors.lastname: Marra
authors.forename: Ali
authors.initials: A
authors.lastname: Guermazi
mesh_terms: D001842:Bone and Bones / Q000473:pathology; D002061:Bursa, Synovial / Q000473:pathology; D006801:Humans; D007719:Knee Joint / Q000473:pathology*; D008022:Ligaments / Q000473:pathology; D008279:Magnetic Resonance Imaging; D020370:Osteoarthritis, Knee / Q000473:pathology*; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000473:pathology*