Eyebrow papule in an elderly man.
A 70-year-old Caucasian man presented with a several-month history of a solitary, asymptomatic papule on the left eyebrow. His medical history included stage 1A lentigo maligna melanoma and multiple non-melanoma skin cancers. Physical examination demonstrated a solitary 5-mm smooth, dome-shaped skin colored papule with subtle central erosion on the left eyebrow. No overlying telangiectasias were noted. A biopsy of the lesion was performed. The lesion was composed of plump spindle cells arranged in a plexiform pattern in the background of thick, keloidal collagen bundles. The lesional cells were NKI/C3-positive and S-100-negative. A diagnosis of cellular neurothekeoma was made.
Clark
F Landon
FL
Department of Dermatology, Stanford University Medical Center, USA.
Somoano
Brian
B
Taube
Janis
J
Egbert
Barbara
B
Kim
Jinah
J
D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002294:Carcinoma, Squamous Cell; D005138:Eyebrows / Q000473:pathology*; D005153:Facial Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D018327:Hutchinson's Melanotic Freckle; D008297:Male; D008545:Melanoma; D016609:Neoplasms, Second Primary / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D018321:Neurothekeoma / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D010980:Platelet Membrane Glycoproteins / Q000032:analysis; D012878:Skin Neoplasms; D060149:Tetraspanin 30
D015703:Antigens, CD; D014408:Biomarkers, Tumor; C554586:CD63 protein, human; D010980:Platelet Membrane Glycoproteins; D060149:Tetraspanin 30