title: Surgery for bronchogenic cysts: always easy?
abstract: A few cases of major complications after surgery for bronchogenic cyst have been reported. The purpose of this study was to analyze the complicated and unusual cases among 30 consecutive patients with bronchogenic cysts treated surgically at our institution between 1975 and 2007. There were 3 cases of mediastinal bronchogenic cyst characterized by significant surgical complications or very unusual pathological findings. The operations were performed through a thoracotomy in 25 patients, and by video-assisted thoracoscopic surgery in 5. Two patients suffered iatrogenic injury of the contralateral main bronchus during excision of a mediastinal cyst; in one of them, late development of foreign body granuloma was related to migration towards the bronchial wall of cyanoacrylate used to reinforce suturing of the bronchial tear. Histological examination of one resected specimen showed a large-cell anaplastic carcinoma arising from the wall of a mediastinal bronchogenic cyst. Bronchogenic cysts should be excised before they become symptomatic or infected, which leads to more difficult surgery and complications. The small risk of developing malignancy within a bronchogenic cyst also justifies early intervention.
authors.affiliation: Thoracic Surgery Unit, Department of Cardiothoracic and Vascular Surgery, Siena University Hospital, Siena, Italy. felicegranato@yahoo.it
authors.forename: Felice
authors.initials: F
authors.lastname: Granato
authors.forename: Luca
authors.initials: L
authors.lastname: Voltolini
authors.forename: Claudia
authors.initials: C
authors.lastname: Ghiribelli
authors.forename: Luca
authors.initials: L
authors.lastname: Luzzi
authors.forename: Sara
authors.initials: S
authors.lastname: Tenconi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Gotti
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001994:Bronchogenic Cyst / Q000150:complications / Q000601:surgery*; D001999:Bronchoscopy; D018287:Carcinoma, Large Cell / Q000209:etiology* / Q000473:pathology; D003487:Cyanoacrylates / Q000009:adverse effects; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007049:Iatrogenic Disease; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013510:Pulmonary Surgical Procedures / Q000009:adverse effects*; D012086:Reoperation; D012189:Retrospective Studies; D013536:Suture Techniques / Q000009:adverse effects; D020775:Thoracic Surgery, Video-Assisted / Q000009:adverse effects*; D013908:Thoracotomy / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003487:Cyanoacrylates