title: Sustainable effects on suicidality were found for the Nuremberg alliance against depression.
abstract: During an intense four-level community-based intervention program conducted in Nuremberg (490,000 inhabitants) in 2001 and 2002 [Nuremberg Alliance Against Depression (NAD)], the number of suicidal acts (main outcome completed + attempted suicides) had dropped significantly (-21.7%), a significant effect compared with the baseline year and the control region (Wuerzburg, about 290,000 inhabitants). To assess the sustainability of the intervention effects the number of suicidal acts was assessed in the follow-up year (2003), after the termination of the 2-year intervention. Also, in the follow-up year (2003), the reduction in suicidal acts compared with the baseline year in Nuremberg (2000 vs. 2003: -32.4%) was significantly larger than that in the control region (P = 0.0065). The reduction was even numerically larger than that of the intervention years (2001, 2002). Thus, 1 year after the end of the main intervention, preventive effects on suicidality of the NAD remain at least stable. The four-level intervention concept appears to be cost-effective and is presently implemented in many European regions.
authors.affiliation: Department of Psychiatry, University of Leipzig, Semmelweisstr. 10, 04103, Leipzig, Germany. Ulrich.Hegerl@medizin.uni-leipzig.de
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hegerl
authors.forename: Roland
authors.initials: R
authors.lastname: Mergl
authors.forename: Inga
authors.initials: I
authors.lastname: Havers
authors.forename: Armin
authors.initials: A
authors.lastname: Schmidtke
authors.forename: Hartmut
authors.initials: H
authors.lastname: Lehfeld
authors.forename: Günter
authors.initials: G
authors.lastname: Niklewski
authors.forename: David
authors.initials: D
authors.lastname: Althaus
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D012044:Regression Analysis; D012189:Retrospective Studies; D013405:Suicide / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D000092864:Suicide Prevention
chemical_list: D000928:Antidepressive Agents