title: Granular cell tumor of the breast: a case report and review of literature.
abstract: A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.
authors.affiliation: Institute of Pathology, Medical Faculty, University of "St Cyrill and Methodius" Street Vodnjanska bb, Skopje, 1000 Republic of Macedonia. v_filipovski@yahoo.com
authors.forename: Vanja
authors.initials: V
authors.lastname: Filipovski
authors.forename: Saso
authors.initials: S
authors.lastname: Banev
authors.forename: Vesna
authors.initials: V
authors.lastname: Janevska
authors.forename: Blagica
authors.initials: B
authors.lastname: Dukova