Comparative study on iron release from soybean (Glycine max) seed ferritin induced by anthocyanins and ascorbate.
Anthocyanins have received much attentions due to their various activities. Phytoferritin represents a novel alternative for iron supplementation. In the present study, it was found that all tested anthocyanins such as cyanidin (Cy), delphinidin (Dp), delphinidin-3-O-glucoside (Dp3glc), malvidin (Mv), petunidin (Pt), and petunidin-3-O-glucoside (Pt3glc) had a strong interaction with SSF, respectively, resulting in iron release from soybean seed ferritin (SSF) just as for ascorbate. The order of iron release from SSF is as follows: Dp>Cy>Pt>Mv>Dp3glc>Pt3glc. Their ability to liberate iron from SSF is associated with the size of the molecules and the chemical structures but mainly depends on their chelating activity with Fe2+. Interestingly, these pigments inhibited SSF degradation during the iron release to different extents while ascorbate did not. The difference in protective effects on SFF between ascorbate and the anthocyanins is in good agreement with their different Fe2+-chelating activities.
Deng
Jianjun
J
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, People's Republic of China.
Cheng
Jianjun
J
Liao
Xiayun
X
Zhang
Tuo
T
Leng
Xiaojing
X
Zhao
Guanghua
G
D000872:Anthocyanins / Q000737:chemistry*; D001205:Ascorbic Acid / Q000737:chemistry*; D005293:Ferritins / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D007502:Iron Chelating Agents / Q000737:chemistry*; D007700:Kinetics; D011485:Protein Binding; D012639:Seeds / Q000737:chemistry; D013025:Glycine max / Q000737:chemistry*
D000872:Anthocyanins; D007502:Iron Chelating Agents; D005293:Ferritins; D007501:Iron; D001205:Ascorbic Acid