title: Marchiafava-Bignami disease: Role of neuroimaging in the diagnosis and management of acute disease.
abstract: Marchiafava-Bignami disease (MBD), a rare disorder most commonly seen in patients with a history of alcohol consumption, involves progressive demyelination and subsequent necrosis of the corpus callosum. Because clinical signs are nonspecific, the role of computed tomography and magnetic resonance imaging is essential to confirm the diagnosis. Early diagnosis with imaging and prompt treatment may improve the prognosis of MBD.
authors.affiliation: Department of Radiodiagnosis, Dr. Ram Manohar Lohia Hospital and PGIMER, New Delhi, India. dr_shahinaindia@yahoo.com
authors.forename: Shahina
authors.initials: S
authors.lastname: Bano
authors.forename: Shibani
authors.initials: S
authors.lastname: Mehra
authors.forename: Sacchida Nand
authors.initials: SN
authors.lastname: Yadav
authors.forename: Vikas
authors.initials: V
authors.lastname: Chaudhary
mesh_terms: D000208:Acute Disease; D000328:Adult; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D054319:Marchiafava-Bignami Disease / Q000175:diagnosis* / Q000628:therapy*; D015898:Tomography Scanners, X-Ray Computed