Developments and applications of capillary microextraction techniques: a review.
Sample preparation is important for isolating desired components from complex matrices and greatly influences their reliable and accurate analysis. Recent trends in sample preparation include miniaturization, automation, high-throughput performance, and reduction in solvent consumption and operation time. This review focuses on novel microextraction techniques using capillaries for off-line and on-line sample preparation. Open-tubular trapping (OTT), in-tube solid-phase microextraction (SPME), wire-in-tube SPME, fiber-in-tube solid-phase extraction (SPE), sorbent-packed capillary in-tube SPME and monolithic capillary in-tube SPME are critically evaluated and applications of these techniques in biological, pharmaceutical, environmental and food analyses are summarized.
Kataoka
Hiroyuki
H
School of Pharmacy, Shujitsu University, 1-6-1, Nishigawara, Okayama 703-8516, Japan. hkataoka@shujitsu.ac.jp
Ishizaki
Atsushi
A
Nonaka
Yuko
Y
Saito
Keita
K
D001331:Automation; D004785:Environmental Pollutants / Q000032:analysis; D005504:Food Analysis; D057166:High-Throughput Screening Assays / Q000379:methods; D008904:Miniaturization; D004364:Pharmaceutical Preparations / Q000032:analysis; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*
D004785:Environmental Pollutants; D004364:Pharmaceutical Preparations