title: Increased yields and simplified purification with a second-generation cobalt catalyst for the oxidative formation of trans-THF rings.
abstract: The synthesis of a second-generation cobalt catalyst for the formation of trans-THF products via the Mukaiyama aerobic oxidative cyclization is reported. Two procedures have been developed with the new water-soluble catalyst that give superior yields and greatly simplify purification compared to the previous catalysts.
authors.affiliation: The University of Western Ontario, Department of Chemistry, London, Ontario, N6A 5B7.
authors.forename: Cory
authors.initials: C
authors.lastname: Palmer
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Morra
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Stevens
authors.forename: Barbora
authors.initials: B
authors.lastname: Bajtos
authors.forename: Ben P
authors.initials: BP
authors.lastname: Machin
authors.forename: Brian L
authors.initials: BL
authors.lastname: Pagenkopf
mesh_terms: D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012995:Solubility; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D003035:Cobalt