title: Central neurocytoma: a multi-disciplinary review.
abstract: Benign central neurocytoma (CN) is a rare neuronal tumour of the central nervous system recognised since the early eighties. More than 300 articles have been published in the literature, mostly comprising of case reports and short series from individual specialties. These tumours, though normally benign, are more often likely to recur after surgery than previously thought. A multi-modality team involvement, therefore, has become increasingly necessary for their optimum management. In this article, the authors from various neurosciences sub-specialties, with a specific interest and experience in managing CN, review the epidemiology, clinical features, pathological findings, radiological characteristics and surgical treatment, with an emphasis on the latest developments in their histology, molecular biology and adjuvant treatment modalities for recurrent or residual disease.
authors.affiliation: Department of Neurosurgery, Regional Neurosciences Unit, Royal Victoria Hospital, Belfast BT126BA, United Kingdom. kchoudhari@hotmail.com
authors.forename: Kishor A
authors.initials: KA
authors.lastname: Choudhari
authors.forename: Chandrasekaran
authors.initials: C
authors.lastname: Kaliaperumal
authors.forename: Ayushi
authors.initials: A
authors.lastname: Jain
authors.forename: Chitra
authors.initials: C
authors.lastname: Sarkar
authors.forename: Mark Yoi Sun
authors.initials: MY
authors.lastname: Soo
authors.forename: Dirk
authors.initials: D
authors.lastname: Rades
authors.forename: Jagmohan
authors.initials: J
authors.lastname: Singh
mesh_terms: D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D018306:Neurocytoma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D019635:Neurosurgical Procedures / Q000379:methods; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome