WormBase: a comprehensive resource for nematode research.
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.
Harris
Todd W
TW
Ontario Institute For Cancer Research, Toronto, ON, Canada. info@toddharris.net
Antoshechkin
Igor
I
Bieri
Tamberlyn
T
Blasiar
Darin
D
Chan
Juancarlos
J
Chen
Wen J
WJ
De La Cruz
Norie
N
Davis
Paul
P
Duesbury
Margaret
M
Fang
Ruihua
R
Fernandes
Jolene
J
Han
Michael
M
Kishore
Ranjana
R
Lee
Raymond
R
Müller
Hans-Michael
HM
Nakamura
Cecilia
C
Ozersky
Philip
P
Petcherski
Andrei
A
Rangarajan
Arun
A
Rogers
Anthony
A
Schindelman
Gary
G
Schwarz
Erich M
EM
Tuli
Mary Ann
MA
Van Auken
Kimberly
K
Wang
Daniel
D
Wang
Xiaodong
X
Williams
Gary
G
Yook
Karen
K
Durbin
Richard
R
Stein
Lincoln D
LD
Spieth
John
J
Sternberg
Paul W
PW
D000483:Alleles; D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000235:genetics*; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D010641:Phenotype; D017434:Protein Structure, Tertiary; D012984:Software; D014157:Transcription Factors
D014157:Transcription Factors