title: Osteotomy of distal radius fracture malunion using a fast remodeling bone substitute consisting of calcium sulphate and calcium phosphate.
abstract: Malunion after a distal radius fracture can be treated with an osteotomy of the distal radius. Autologous iliac crest bone graft is often used to fill the gap, but the procedure is associated with donor site morbidity. In this study a novel fast resorbing biphasic bone substitute consisting of a mixture of calcium sulphate and calcium phosphate is used (Cerament BoneSupport AB, Sweden). Fifteen consecutive patients, with a mean age of 52 (27-71) years were included. All had a malunion after a distal radius fracture and underwent an osteotomy. A fragment specific fixation system, TriMed (TriMed, Valencia, CA), consisting of a Buttress Pin and a Radial Pin Plate were used for fixation and a calcium sulphate and calcium phosphate mixture as bone substitute. The patients were followed for 1 year. Grip strength increased from 61 (28-93)% of the contralateral hand to 85 (58-109)%, p < 0.001. DASH scores decreased from 37 (22-61) to 24 (2-49) p = 0.003. Radiographically all osteotomies healed. An increase of ulnar variance was noted during healing from 1.8 mm immediately postoperatively to 2.6 mm at final follow up. Osteotomy can increase grip strength and decease disability after a malunited fracture. In the present series the bone substitute was replaced by bone, but a minor loss of the achieved radiographic correction was noted in some patients during osteotomy healing. A more rigid fixation may improve the radiographic outcome with this kind of bone substitute.
authors.affiliation: Department of Orthopaedics, Clinical Sciences, Lund University, Lund, Sweden. tony.abramo@med.lu.se
authors.forename: Antonio
authors.initials: A
authors.lastname: Abramo
authors.forename: Mats
authors.initials: M
authors.lastname: Geijer
authors.forename: Philippe
authors.initials: P
authors.lastname: Kopylov
authors.forename: Magnus
authors.initials: M
authors.lastname: Tägil
mesh_terms: D000328:Adult; D000368:Aged; D016723:Bone Remodeling; D018786:Bone Substitutes; D002130:Calcium Phosphates / Q000737:chemistry*; D002133:Calcium Sulfate / Q000737:chemistry*; D004338:Drug Combinations; D017886:Durapatite / Q000737:chemistry*; D005240:Feasibility Studies; D005592:Fracture Fixation; D006801:Humans; D008875:Middle Aged; D010027:Osteotomy; D011446:Prospective Studies
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D004338:Drug Combinations; C582328:cerament; D017886:Durapatite; C020243:calcium phosphate; D002133:Calcium Sulfate