title: Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity.
abstract: Staphylococcal toxic shock syndrome (TSS) has rarely been reported without rash and desquamation. This study describes a patient who met all criteria for TSS except erythroderma and desquamation. The associated staphylococcal superantigen was enterotoxin B. We demonstrate that erythroderma depends on preexisting T cell hypersensitivity amplified by superantigenicity.
authors.affiliation: Department of 1Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
authors.forename: Chandy C
authors.initials: CC
authors.lastname: John
authors.forename: Micah
authors.initials: M
authors.lastname: Niermann
authors.forename: Bazak
authors.initials: B
authors.lastname: Sharon
authors.forename: Marnie L
authors.initials: ML
authors.lastname: Peterson
authors.forename: David M
authors.initials: DM
authors.lastname: Kranz
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Schlievert
mesh_terms: D000293:Adolescent; D003873:Dermatitis, Exfoliative / Q000175:diagnosis / Q000209:etiology*; D004768:Enterotoxins / Q000276:immunology; D005260:Female; D006801:Humans; D012772:Shock, Septic / Q000175:diagnosis / Q000209:etiology*; D012882:Skin Tests; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology*; D018089:Superantigens / Q000276:immunology*
chemical_list: D004768:Enterotoxins; D018089:Superantigens; C031818:enterotoxin B, staphylococcal