title: Neurologic manifestations of transplant complications.
abstract: Neurologic complications affect posttransplant recovery of more than 20% of transplant recipients. Etiology is usually related to surgical procedure of transplantation, primary disorders causing failure of transplanted organ, opportunistic infections, and neurotoxicity of immunosuppressive medications. Risk of opportunistic infections and immunosuppressant neurotoxicity is greatest within the first six months, but it persists along with long-term maintenance immunosuppression required to prevent graft rejection. Neurotoxicity may require alteration of immunosuppressive regimen, and prompt therapy of opportunistic infections improves outcomes.
authors.affiliation: Neurology Service, VA Pittsburgh Healthcare System, University Drive C, Pittsburgh, PA 15240, USA. zivkovics@upmc.edu
authors.forename: Sasa A
authors.initials: SA
authors.lastname: Zivković
authors.forename: Hoda
authors.initials: H
authors.lastname: Abdel-Hamid
mesh_terms: D000328:Adult; D002648:Child; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D014180:Transplantation / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents