T-cell immune monitoring in organ transplantation.
Chronic allograft injury remains the leading cause of graft loss despite improvements in immunosuppression, clinical risk stratification, and state-of-the-art antibody testing. Emerging results indicate that T-cell immune monitoring by cytokine enzyme-linked immunosorbent spot, as part of a comprehensive risk assessment platform, has the potential to guide decision making and improve outcomes after transplantation.
Dinavahi
Rajani
R
Division of Nephrology, Mount Sinai School of Medicine, Recanati/Miller Transplantation Institute, New York, NY 10029, USA. peter.heeger@mssm.edu
Heeger
Peter S
PS
D015331:Cohort Studies; D016207:Cytokines / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006084:Graft Rejection / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007371:Interferon-gamma / Q000276:immunology; D016030:Kidney Transplantation / Q000276:immunology* / Q000473:pathology; D015166:Monitoring, Immunologic / Q000379:methods*; D006435:Renal Dialysis; D018570:Risk Assessment; D013601:T-Lymphocytes / Q000276:immunology*; D014184:Transplantation, Homologous / Q000276:immunology* / Q000473:pathology*; D017211:Treatment Failure; D016896:Treatment Outcome
D016207:Cytokines; D007371:Interferon-gamma