Enzymatic synthesis of UDP-GlcNAc/UDP-GalNAc analogs using N-acetylglucosamine 1-phosphate uridyltransferase (GlmU).
Reports the generation of a library composed of UDP-GlcNAc/UDP-GalNAc and investigates the substrate specificity of Escherichia coli GlcNAc-1-P uridyltransferase GlmU.
Guan
Wanyi
W
National Glycoengineering Research Center and The State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong 250100, People's Republic of China.
Cai
Li
L
Fang
Junqiang
J
Wu
Baolin
B
George Wang
Peng
P
D000117:Acetylglucosamine / Q000737:chemistry*; D004926:Escherichia coli / Q000201:enzymology; D009713:Nucleotidyltransferases / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity; D014530:Uridine Diphosphate / Q000737:chemistry*; D014539:Uridine Diphosphate Sugars / Q000096:biosynthesis* / Q000737:chemistry
D014539:Uridine Diphosphate Sugars; D014530:Uridine Diphosphate; D009713:Nucleotidyltransferases; C023226:UDPacetylglucosamine pyrophosphorylase; D000117:Acetylglucosamine