As many as six tandem reactions in one step! Unprecedented formation of highly functionalized benzothiophenes.
A novel reaction pathway involving 1,3-diketones and 2,2'-dithiodibenzoylchloride that gives access to benzothiophenes with spiroketal, lactone, carbonyl, hydroxyl and carboxylic acid functionalities is discussed.
Gopinath
Pushparathinam
P
Department of Chemistry, Indian Institute of Technology Madras, Chennai, 600 036, India.
Nilaya
Surapaneni
S
Debi
Tripathy Ranjan
TR
Ramkumar
Venkatachalam
V
Muraleedharan
Kannoth Manheri
KM
D002264:Carboxylic Acids; D005663:Furans; D007659:Ketones / Q000737:chemistry; D007783:Lactones; D008722:Methods; D013141:Spiro Compounds; D013876:Thiophenes / Q000138:chemical synthesis*
D002264:Carboxylic Acids; D005663:Furans; D007659:Ketones; D007783:Lactones; D013141:Spiro Compounds; D013876:Thiophenes; C520774:spiroketal; C088015:benzothiophene