Salivary gland tumours as second neoplasms: two cases and literature review.
OBJECTIVE
Patients who survive malignant tumours have an increased risk of second neoplasms, including those of the salivary glands. Mucoepidermoid carcinoma of the parotid gland is by far the most common type of second salivary gland tumour; other types have rarely been reported. We describe here two patients with a second tumour of the salivary glands.


METHODS
The first patient was a 22-year-old woman with a low grade mucoepidermoid carcinoma of the parotid gland, which developed 21 years after completion of chemoradiotherapy for acute lymphoblastic leukaemia. The second patient was a 40-year-old woman with an epithelial-myoepithelial carcinoma of the buccal mucosa, which arose 11 years after treatment for two malignant neoplasms - retroperitoneal liposarcoma and squamous cell carcinoma of the uterine cervix.


CONCLUSIONS
It is mandatory that survivors of cancer should be monitored carefully, so that the complications related to their previous disease and therapy are detected early and managed properly.
Zidar
N
N
Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia. nina.zidar@mf.uni-lj.si
Gale
N
N
Zupevc
A
A
Zargi
M
M
D000328:Adult; D018277:Carcinoma, Mucoepidermoid / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D012468:Salivary Gland Neoplasms / Q000209:etiology* / Q000473:pathology; D055815:Young Adult