[What is the significance of extended spectrum betalactamases in clinical practice?].
Extended spectrum betalactamases (ESBL) confer resistance to most commonly used betalactam antibiotics. Their emergence in Gram negative bacteria was observed after the widespread use of cephalosporins and quinolones. They can cause severe infections in the hospital as well as in the community. Carbapenems remain the first choice of treatment for these infections. Appropriate use of antibiotics could decrease the spread of ESBLs.
Vora
S
S
s.vora@bluewin.ch
Auckenthaler
R
R
D024881:Drug Resistance, Bacterial; D006801:Humans; D001618:beta-Lactamases / Q000502:physiology*
D001618:beta-Lactamases