title: Single drop microextraction--development, applications and future trends.
abstract: Single drop microextraction (SDME) has emerged over the last 10-15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.
authors.affiliation: Department of Chemistry, St. Cloud State University, 366 Wick Science Building, 720 4th Ave. S., St. Cloud, MN 56301-4498, USA. mjeannot@stcloudstate.edu
authors.forename: Michael A
authors.initials: MA
authors.lastname: Jeannot
authors.forename: Andrzej
authors.initials: A
authors.lastname: Przyjazny
authors.forename: John M
authors.initials: JM
authors.lastname: Kokosa
mesh_terms: D005591:Chemical Fractionation / Q000295:instrumentation* / Q000379:methods*; D005544:Forecasting; D009994:Osmolar Concentration; D012997:Solvents / Q000737:chemistry; D013696:Temperature
chemical_list: D012997:Solvents