title: Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease?
abstract: The safety of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with inflammatory bowel disease (IBD) remains unclear. This report discusses potential mechanisms whereby NSAIDs might exacerbate IBD and reviews the available clinical data on the role of NSAIDs in causing exacerbations of ulcerative colitis (UC) and Crohn's disease (CD).
authors.affiliation: Divisions of Gastroenterology (111B1) and Hepatology, VA North Texas Health Care System and the University of Texas Southwestern Medical Center at Dallas, 4500 South Lancaster Road, Dallas, TX 75216, USA. LindaA.Feagins@va.gov
authors.forename: Linda A
authors.initials: LA
authors.lastname: Feagins
authors.forename: Byron L
authors.initials: BL
authors.lastname: Cryer
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D041981:Gastrointestinal Tract / Q000187:drug effects*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000209:etiology*; D012008:Recurrence; D012307:Risk Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal