title: The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department.
abstract: OBJECTIVE
  To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death.
  
  
  METHODS
  In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (-70 degrees C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement.
  
  
  RESULTS
  Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with < or = two cytokines elevated.
  
  
  CONCLUSIONS
  A cytokine panel might be useful for risk stratification for HF/death.
authors.affiliation: Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. kavsakp@mcmaster.ca
authors.forename: Peter A
authors.initials: PA
authors.lastname: Kavsak
authors.forename: Alice M
authors.initials: AM
authors.lastname: Newman
authors.forename: Dennis T
authors.initials: DT
authors.lastname: Ko
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Macrae
authors.forename: Allan S
authors.initials: AS
authors.lastname: Jaffe
mesh_terms: D000368:Aged; D002637:Chest Pain / Q000097:blood*; D016207:Cytokines / Q000097:blood*; D003643:Death; D004636:Emergency Service, Hospital; D005260:Female; D006333:Heart Failure / Q000097:blood*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors
chemical_list: D016207:Cytokines