title: A surgically treated case of Lhermitte-Duclos disease with a precise natural history and high uptake of FDG on PET.
abstract: We describe herein a surgically treated case of Lhermitte-Duclos disease in a 33-year-old man. The clinical presentation seemed typical in terms of symptoms, neurological signs, and neuroimaging. High and heterogenous fluorodeoxyglucose uptake in positron emission tomography study is presented and discussed. Furthermore, we performed volumetric analysis of the tumor with sequential magnetic resonance imaging over the course of 7 years before surgery, making this report the first with a long-term natural history, revealing that this rare disease entity may have a neoplastic nature.
authors.affiliation: Department of Neurosurgery, Osaka University Graduate School of Medicine, Yamadaoka 2-2, E6 Suita, Osaka 565-0871, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Goto
authors.forename: Naoya
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Okita
authors.forename: Tetsu
authors.initials: T
authors.lastname: Goto
authors.forename: Carter
authors.initials: C
authors.lastname: Rabo
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hirayama
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Horikawa
authors.forename: Manabu
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Naoki
authors.initials: N
authors.lastname: Kagawa
authors.forename: Toshiki
authors.initials: T
authors.lastname: Yoshimine
mesh_terms: D000328:Adult; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006223:Hamartoma Syndrome, Multiple / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods*
chemical_list: D019788:Fluorodeoxyglucose F18