title: Abdominal wall reconstruction: lessons learned from 200 "components separation" procedures.
abstract: OBJECTIVE
  To determine the efficacy and describe the evolution of the "components separation" technique for abdominal wall repair in 200 consecutive patients.
  
  
  METHODS
  Retrospective medical record review.
  
  
  METHODS
  Northwestern Memorial Hospital, Chicago, Illinois.
  
  
  METHODS
  Two hundred consecutive patients who underwent ventral hernia repair using the components separation technique.
  
  
  METHODS
  Biological and permanent meshes were used in select patients to augment the repair of the midline fascial closure but were not used as "bridging" materials.
  
  
  METHODS
  Hernia recurrence rates and major and minor complication rates for the overall series and for the different techniques.
  
  
  RESULTS
  Primary components separation (n = 158) yielded a 22.8% recurrence rate. Closure of the midline tissues with augmentation of the repair using an acellular cadaveric dermis underlay (n = 18) had a 33.3% recurrence rate requiring a second operation, whereas intra-abdominal soft polypropylene mesh (n = 18) had 0% recurrence (P = .04). Elevated body mass index was a significant risk factor predicting hernia recurrence (P = .003). Contamination (P = .04) and enterocutaneous fistula (P = .02) at the time of surgery were associated with increased major complications, whereas body mass index (P = .01) and diabetes mellitus (P = .04) were associated with increased minor complications.
  
  
  CONCLUSIONS
  Large complex hernias can be reliably repaired using the components separation technique despite the presence of open wounds, the need for bowel surgery, and numerous comorbidities. The long-term strength of the hernia repair is not augmented by acellular cadaveric dermis but seems to be improved with soft polypropylene mesh.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Jason H
authors.initials: JH
authors.lastname: Ko
authors.forename: Edward C
authors.initials: EC
authors.lastname: Wang
authors.forename: David M
authors.initials: DM
authors.lastname: Salvay
authors.forename: Benjamin C
authors.initials: BC
authors.lastname: Paul
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Dumanian
mesh_terms: D034861:Abdominal Wall / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D000367:Age Factors; D000368:Aged; D002102:Cadaver; D015331:Cohort Studies; D020405:Dermis / Q000637:transplantation; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011126:Polypropylenes / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000503:physiopathology / Q000601:surgery; D011336:Probability; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000379:methods*; D017568:Rectus Abdominis / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D013526:Surgical Mesh; D013536:Suture Techniques; D013718:Tensile Strength; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D011126:Polypropylenes