title: Atypical presentation of an apical pseudoaneurysm in a patient on prolonged left ventricular mechanical support.
abstract: Prolonged support with left ventricular assist system (LVAS) increases the risk of device-related infection. We experienced a rare complication of LVAS: an infectious aneurysm at the apical cannula, which appeared with atypical presentation. A 27-year-old male, who developed acute aggravation of dilated cardiomyopathy, was placed on extra-corporeal type LVAS. Six months later, the patient suffered from methicillin-resistant Staphylococcus aureus (MRSA) sepsis that lasted for as long as three months despite intensive antibiotic therapy. At 17 months after the implantation, he presented with obstructive ileus. Monthly assessment with transthoracic echocardiography (TTE) did not document any abnormalities around the ventricle. A contrast computed tomographic (CT) scan revealed a huge apical aneurysm protruding into the preperitoneal space. The aneurysm oppressed the transverse colon, resulting in obstructive ileus. Aneurysmectomy was carried out and MRSA was identified from the resected tissue. We reached the precise diagnosis with a CT-scan, although routine assessment with TTE failed to reveal abnormalities. Knowledge of this complication is essential in LVAS management. This is certainly rare, but possibly occurs in all the patients on prolonged LVAS support. Early and accurate diagnosis together with aggressive intervention would bring favorable outcome in such serious cases.
authors.affiliation: Department of Cardiovascular Surgery, Kyushu University Heart Center, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Taketoshi
authors.initials: T
authors.lastname: Maeda
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Tanoue
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Nakashima
authors.forename: Ryuji
authors.initials: R
authors.lastname: Tominaga
mesh_terms: D000328:Adult; D017541:Aneurysm, False / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002311:Cardiomyopathy, Dilated / Q000628:therapy*; D003108:Colonic Diseases / Q000209:etiology; D003248:Constipation / Q000209:etiology; D004452:Echocardiography; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D045823:Ileus / Q000209:etiology; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
chemical_list: D000900:Anti-Bacterial Agents