title: Mucormycosis infection of the lacrimal sac.
abstract: Biopsy of the lacrimal sac for patients with primary acquired nasolacrimal duct obstruction has been a topic of debate for many years. The authors present a case of a 72-year-old immunocompetent woman with a 2-month history of epiphora secondary to nasolacrimal duct obstruction. During an uneventful dacryorhinocystostomy, a routine lacrimal sac biopsy was performed and revealed mucormycosis. After appropriate infectious disease consultation, intensive antifungal therapy was given uneventfully. The patient has not had any signs of active Mucor infection after treatment in 6 months of follow up. This case demonstrates the utility of routine lacrimal sac biopsy and stands as an example of the potential to miss a serious diagnosis.
authors.affiliation: Departments of Ophthalmology and Visual Sciences, University of Illinois at Chicago College of Medicine, Chicago, Illinois 60612, U.S.A.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Kapur
authors.forename: Vinay K
authors.initials: VK
authors.lastname: Aakalu
authors.forename: Carey Z
authors.initials: CZ
authors.lastname: August
authors.forename: Robert A
authors.initials: RA
authors.lastname: Weiss
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D003608:Dacryocystorhinostomy; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007765:Lacrimal Apparatus / Q000187:drug effects / Q000382:microbiology*; D007767:Lacrimal Duct Obstruction / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D009091:Mucormycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B