Novel and improved technologies for tuberculosis diagnosis: progress and challenges.
Despite a decade of success in improving cure rates for tuberculosis (TB), diagnosis and case detection remain a major obstacle to TB control. This article reviews the existing evidence base on TB diagnostics, describes the progress of new technologies, and ends with a review of cost-effectiveness and modeling studies on the potential effect of new diagnostics in TB control.
Pai
Madhukar
M
Department of Epidemiology, Biostatistics & Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, H3A 1A2, Canada. madhukar.pai@mcgill.ca
Minion
Jessica
J
Sohn
Hojoon
H
Zwerling
Alice
A
Perkins
Mark D
MD
D001431:Bacteriological Techniques / Q000639:trends*; D019937:Diagnostic Techniques and Procedures / Q000639:trends*; D006801:Humans; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis*