title: [Splenectomy in hereditary hemolytic anemia: 82 Tunisian cases].
abstract: BACKGROUND
  Splenectomy is frequently advised in hereditary hemolytic anemia. Severe complications could occur after splenectomy.
  
  
  OBJECTIVE
  To provide the indication and benefit of splenectomy
  
  
  METHODS
  clinical and biological patterns were performed in a retrospective study of 82 patients: 17 homozygous beta thalassemia, 17 thalassemia intermedia, 33 heterozygote Hb/S beta thalassemia and 15 hereditary spherocytosis.
  
  
  RESULTS
  Splenectomy was performed for: Hypertransfusion in homozygous thalassemia, hereditary spherocytosis; hypersplenism in Thalassemia intermedia and splenic sequestration in heterozygote HbS/beta thalassemia. The benefit of splenectomy was proved in hereditary spherocytosis (100%), heterozygote HbS/beta thalassemia (90%) and thalassemia intermedia (75%); nevertheless in homozygous beta thalassemia. Post splenectomical complication are often thrombocytosis, thrombosis and infections.
  
  
  CONCLUSIONS
  Splenectomy should be performed in hereditary hemolytic anemia to reduce and avoid transfusion.
authors.affiliation: Service d'Hématologie biologique Hôpital Aziza Othmana, Tunis.
authors.forename: Raouf
authors.initials: R
authors.lastname: Hafsia
authors.forename: Sami
authors.initials: S
authors.lastname: Zriba
authors.forename: Emna
authors.initials: E
authors.lastname: Gouider
authors.forename: Naouel
authors.initials: N
authors.lastname: Ben Salah
authors.forename: Wejdane
authors.initials: W
authors.lastname: Borji
authors.forename: Abdejelil
authors.initials: A
authors.lastname: Zaouche
mesh_terms: D000293:Adolescent; D000328:Adult; D000745:Anemia, Hemolytic, Congenital / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013156:Splenectomy; D014416:Tunisia; D055815:Young Adult