Alasmontamine A, A first tetrakis monoterpene indole alkaloid from Tabernaemontana elegans.
A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.
Hirasawa
Yusuke
Y
Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo 142-8501, Japan.
Miyama
Saori
S
Hosoya
Takahiro
T
Koyama
Koichiro
K
Rahman
Abdul
A
Kusumawati
Idha
I
Zaini
Noor Cholies
NC
Morita
Hiroshi
H
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D046948:Secologanin Tryptamine Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D030014:Tabernaemontana / Q000737:chemistry
D000972:Antineoplastic Agents, Phytogenic; D046948:Secologanin Tryptamine Alkaloids; C546676:alasmontamine A