title: A case of unforeseen intractable severe bacteremia due to Acinetobacter baumannii--an efficacy of sulbactam--.
abstract: We report the case of a 62-year-old woman with Acinetobacter baumannii bacteremia. She was admitted to our hospital with ventricular tachycardia and was subsequently diagnosed with idiopathic ventricular tachycardia, with no structural heart disease. However, 12 days after admission, she suddenly developed a high-grade fever with chills and diarrhea. Her blood cultures revealed A. baumannii, and the patient was treated with meropenem and amikacin sulfate. Yet, the patient's symptoms and clinical signs became worse. We then began to administer a large quantity of intravenous ampicillin-sulbactam, and the patient improved dramatically. Although rare, bloodstream infection caused by A. baumannii tends to be severe. Therefore, when A. baumannii is found in a patient's bloodstream, clinicians should start appropriate treatment immediately and should recall ampicillin-sulbactam as a sensible option for treatment.
authors.affiliation: Fourth Department of Internal Medicine, Shimane University Faculty of Medicine, Shimane 693-8501, Japan. yukihiro@med.shimane-u.ac.jp
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Toshio
authors.initials: T
authors.lastname: Shimada
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Tanabe
authors.forename: Masatake
authors.initials: M
authors.lastname: Sato
authors.forename: Jun
authors.initials: J
authors.lastname: Kitamura
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Sato
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yoshitomi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sakane
mesh_terms: D000151:Acinetobacter Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D040981:Acinetobacter baumannii / Q000254:growth & development / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D001769:Blood / Q000382:microbiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D013407:Sulbactam / Q000627:therapeutic use*; D016896:Treatment Outcome; D047090:beta-Lactams / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D013407:Sulbactam