title: 3-(2-aminophenyl)-4-methyl-1,3-thiazole-2(3H)-thione as an ecofriendly sulphur transfer agent to prepare alkanethiols in high yield and high purity.
abstract: A new process is described for preparing very pure linear alkanethiols and linear alpha,omega-alkanedithiols using a sequential alkylation of the title compound, followed by a ring closure to quantitatively give the corresponding 3-methyl[1,3]thiazolo[3,2-a]-[3,1]benzimidazol-9-ium salt and the alkanethiol derivative under mild conditions. The alkanethiol and the heteroaromatic salt are easily separated by a simple extraction process. The intermediate thiazolium quaternary salts resulting from the first reaction step can be isolated in quantitative yields, affording an odourless protected form of the thiols.
authors.affiliation: Département de Chimie, Faculté de Sciences, Université d'Oran-es-Senia, Algeria. mmehdid@yahoo.fr
authors.forename: Mohammed Amine
authors.initials: MA
authors.lastname: Mehdid
authors.forename: Ayada
authors.initials: A
authors.lastname: Djafri
authors.forename: Christian
authors.initials: C
authors.lastname: Roussel
authors.forename: Federico
authors.initials: F
authors.lastname: Andreoli
mesh_terms: D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*; D053778:Thiazolidines / Q000138:chemical synthesis / Q000737:chemistry; D014050:Toluene / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D013438:Sulfhydryl Compounds; D053778:Thiazolidines; D014050:Toluene; C033089:thiazoline-2-thione; D013455:Sulfur; C004848:dithiol