title: The demographic characteristics of histological types of gastric cancer with gender, age, and tumor location.
abstract: OBJECTIVE
  The objective of this paper is to study demographic characteristics of different histological types with patient's gender, age, and tumor location in gastric cancer.
  
  
  METHODS
  Three hundred and fifty-one patients who had gastric cancer and undergone a D2 or greater gastrectomy were analyzed retrospectively. The association between gender and age, tumor location and histological types, including tubular adenocarcinoma (TUB), poorly differentiated adenocarcinoma (POR), signet-ring cell carcinoma (SIG), mucinous adenocarcinoma, and undifferentiated carcinoma (UND), were analyzed by chi-square test or Fisher exact test.
  
  
  RESULTS
  The proportion of TUB in males was higher than that in females (52.4% vs 30.1%, p value of 0.000), and the proportion of SIG in females was higher than that in males (26.2% vs 12.9%, p = 0.002). The prevalence of TUB in patients aged >60 years (54.9%) was significantly higher than that in patients aged 40-60 years (42.2%) and <40 years (24.1%). The prevalence of SIG in the group aged <40 years was significantly higher than that in the other two age groups (44.8% vs 15.6%, 12.7%, p = 0.000). Among the three age groups, the proportion of UND was highest in patients aged 40-60 years (7.8% vs 0%, 1.4%, p = 0.012). The proportion of TUB was highest in the upper part of the stomach as compared to the middle and lower parts of the stomach (56.1% vs 30.8%, 48.2%, p = 0.016). POR was commonly found in the middle part of the stomach as compared to the upper and lower parts (44.6% vs 26.1%, 14.6%, p = 0.002).
  
  
  CONCLUSIONS
  TUB was commonly found in the upper part of the stomach in old, male patients, and SIG was the most common histological type in young, female patients. UND was common in middle-aged patients, and POR was mainly found in the middle part of the stomach.
authors.affiliation: Department of General Surgery, Liaocheng People's Hospital, 67, West Dongchang Road, Liaocheng, Shandong Province 252000, China. junxiuyu@hotmail.com
authors.forename: Junxiu
authors.initials: J
authors.lastname: Yu
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhao
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D002277:Carcinoma / Q000453:epidemiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000473:pathology*