title: [Streptococcus pyogenes or group A streptococcal infections in child: French national reference center data].
abstract: Since the 1980s, infections due to Streptococcus pyogenes or group A streptococci (GAS) were marked by the increase in invasive infections and the emergence of clones which were resistant to macrolides. Those challenges led the French national reference center for streptococci to enhance the epidemiological survey and the characterization of GAS strains, in collaboration with the National Institute for Public Health Surveillance. Active surveillance is of major importance for implementation of therapeutic and prophylactic guidelines and for evaluation of future streptococcal vaccines.
authors.affiliation: Centre national de référence des streptocoques (CNR-Strep), service de bacteriologie, hôpital Saint-Vincent-de-Paul, 75014 Paris, France. philippe.bidet@rdb.aphp.fr
authors.forename: P
authors.initials: P
authors.lastname: Bidet
authors.forename: C
authors.initials: C
authors.lastname: Plainvert
authors.forename: C
authors.initials: C
authors.lastname: Doit
authors.forename: P
authors.initials: P
authors.lastname: Mariani-Kurkdjian
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
authors.forename: A
authors.initials: A
authors.lastname: Lepoutre
authors.forename: A
authors.initials: A
authors.lastname: Bouvet
authors.forename: C
authors.initials: C
authors.lastname: Poyart
authors.forename: E
authors.initials: E
authors.lastname: Bingen
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks / Q000517:prevention & control; D004334:Drug Administration Schedule; D024901:Drug Resistance, Multiple, Bacterial; D005060:Europe; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005602:France; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D017410:Practice Guidelines as Topic; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D013297:Streptococcus pyogenes / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity; D014069:Tonsillitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D037521:Virulence Factors / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D037521:Virulence Factors