Reduced short-term memory span in aphasia and susceptibility to interference: contribution of material-specific maintenance deficits.
Semantic short-term memory (STM) deficits have been traditionally defined as an inability to maintain semantic representations over a delay (Martin et al., 1994b). Yet some patients with semantic STM deficits make numerous intrusions of items from previously presented lists, thus presenting an interesting paradox: why should an inability to maintain semantic representations produce an increase in intrusions from earlier lists? In this study, we investigated the relationship between maintenance deficits and susceptibility to interference in a group of 20 aphasic patients characterized with weak semantic or weak phonological STM. Patients and matched control participants performed a modified item-recognition task designed to elicit semantic or phonological interference from list items located one, two, or three trials back (Hamilton & Martin, 2007). Controls demonstrated significant effects of interference in both versions of the task. Interference in patients was predicted by the type and severity of their STM deficit; that is, shorter semantic spans were associated with greater semantic interference and shorter phonological spans were associated with greater phonological interference. We interpret these results through a new perspective, the reactivation hypothesis, and we discuss their importance for accounts emphasizing the contribution of maintenance mechanisms for STM impairments in aphasia as well as susceptibility to interference.
Barde
Laura H F
LH
Moss Rehabilitation Research Institute, Philadelphia, PA, United States; University of Pennsylvania, Philadelphia, PA, United States. lbarde@stanford.edu
Schwartz
Myrna F
MF
Chrysikou
Evangelia G
EG
Thompson-Schill
Sharon L
SL
D000328:Adult; D000368:Aged; D001037:Aphasia / Q000503:physiopathology / Q000523:psychology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000503:physiopathology / Q000523:psychology*; D008570:Memory, Short-Term; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D011597:Psychomotor Performance; D011930:Reaction Time; D012660:Semantics; D012691:Serial Learning; D012720:Severity of Illness Index