title: Anticancer drugs discovery and development from marine organism.
abstract: The chemical and biological diversity of the different marine evolutionary group is endless and therefore, this is an amazing resource for the discovery of new anticancer drugs. Comprising 34 of the 36 Phyla of life, marine ecosystems are indeed our last genetic diversity and biotechnological boundary; terrestrial systems possess only 17 Phyla. Sponges, coelenterates and microorganisms are the foremost resources of therapeutic compounds. Algae, echinoderms, tunicates, mollusks, bryozoans are also the sources of anticancer drugs from marine resources. We highlight the past and current status of marine anticancer pharmacology using different marine groups.
authors.affiliation: Department of Marine Biotechnology and Resources, College of Marine Science and Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohisung, Taiwan. drchiranjib@yahoo.com
authors.forename: Chiranjib
authors.initials: C
authors.lastname: Chakraborty
authors.forename: Chi-Hsin
authors.initials: CH
authors.lastname: Hsu
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Wen
authors.forename: Chan-Shing
authors.initials: CS
authors.lastname: Lin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D055808:Drug Discovery / Q000639:trends*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D009792:Oceans and Seas
chemical_list: D000970:Antineoplastic Agents