Laser lipolysis with pulsed 1064 nm Nd:YAG laser for the treatment of gynecomastia.
BACKGROUND
Lipolysis using laser is currently widely used for reducing localized fat. A 1064 nm neodynium-doped yttrium aluminum garnet (Nd:YAG) laser lipolysis was investigated in this study to evaluate its efficacy and safety in the treatment of gynecomastia.


METHODS
Five male patients diagnosed with gynecomastia were enrolled in this study, which was designed as a controlled split-breast trial. One breast of each patient was subjected to laser lipolysis and was then compared with a contralateral breast. Photographs and clinical assessments were obtained before the lipolysis, and at the fourth and eighth weeks thereafter. Computed tomography (CT) scan and ultrasound (US) imaging were used to evaluate the changes in the breasts' thicknesses.


RESULTS
The mean chest circumference was found to have been significantly reduced 8 weeks after the laser lipolysis. The clinical outcomes of the laser lipolysis were considered favorable by both the patients and clinicians. The CT and US scans showed that the thicknesses of the treated right breasts reduced more than those of the left breasts were 8 weeks after the laser lipolysis. The side effects (pain, edema, and ecchymosis) were minimal and disappeared shortly after they first manifested. Limitations The limitations of this study are that it employed small treatment groups and short-term follow-up.


CONCLUSIONS
This study demonstrated that gynecomastia can be treated effectively and safely through 1064 nm Nd:YAG laser lipolysis.
Rho
Yong Kwan
YK
Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, South Korea.
Kim
Beom Joon
BJ
Kim
Myeung Nam
MN
Kang
Kweon Soo
KS
Han
Hee Jin
HJ
D000328:Adult; D006177:Gynecomastia / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D015187:Lipectomy / Q000379:methods*; D008297:Male; D008327:Mammography; D009354:Neodymium; D017060:Patient Satisfaction; D014057:Tomography, X-Ray Computed; D016217:Ultrasonography, Mammary
D009354:Neodymium