title: A small supernumerary marker chromosome present in a Turner syndrome patient not derived from X- or Y-chromosome: a case report.
abstract: BACKGROUND
  Small supernumerary marker chromosomes (sSMC) can be present in numerically abnormal karyotypes like in a 'Turner-syndrome karyotype' mos 45,X/46,X,+mar.
  
  
  RESULTS
  Here we report the first case of an sSMC found in Turner syndrome karyotypes (sSMCT) derived from chromosome 14 in a Turner syndrome patient. According to cytogenetic and molecular cytogenetic characterization the karyotype was 46,X,+del(14)(q11.1). The present case is the third Turner syndrome case with an sSMCT not derived from the X- or the Y-chromosome.
  
  
  CONCLUSIONS
  More comprehensive characterization of such sSMCT might identify them to be more frequent than only ~0.6% in Turner syndrome cases according to available data.
authors.affiliation: Jena University Hospital, Institute of Human Genetics and Anthropology, Kollegiengasse 10, D-07743 Jena, Germany. i8lith@mti.uni-jena.de.
authors.forename: Frenny
authors.initials: F
authors.lastname: Sheth
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Ewers
authors.forename: Nadezda
authors.initials: N
authors.lastname: Kosyakova
authors.forename: Anja
authors.initials: A
authors.lastname: Weise
authors.forename: Jayesh
authors.initials: J
authors.lastname: Sheth
authors.forename: Manisha
authors.initials: M
authors.lastname: Desai
authors.forename: Joris
authors.initials: J
authors.lastname: Andrieux
authors.forename: Joris
authors.initials: J
authors.lastname: Vermeesch
authors.forename: Ahmed B
authors.initials: AB
authors.lastname: Hamid
authors.forename: Monika
authors.initials: M
authors.lastname: Ziegler
authors.forename: Thomas
authors.initials: T
authors.lastname: Liehr