Microwave assisted efficient synthesis of imidazole-based privileged structures.
A simple and efficient microwave assisted synthesis of imidazobenzoxazines, imidazobenzoxazin-5-ones, and imidazobenzoxazin-5-thiones with broad chemistry scope is described. The molecules were prepared both under conventional as well as microwave heating conditions, to provide in high yields with clean and scalable reactions a small library of imidazole-based privileged structures for drug discovery.
Fantini
Marco
M
Dipartimento Farmaceutico, Università degli Studi di Parma, Parma, Italy.
Zuliani
Valentina
V
Spotti
Mario A
MA
Rivara
Mirko
M
D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D007093:Imidazoles / Q000138:chemical synthesis*; D008872:Microwaves; D015394:Molecular Structure
D007093:Imidazoles