Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide.
Regioselective synthesis of halohydrin esters was achieved by (1) the reaction of acyl halides with epoxides and (2) the rhodium-catalyzed three-component coupling reaction of alkyl halides, carbon monoxide, and epoxides.
Nakano
Koji
K
Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Kodama
Shunsuke
S
Permana
Yessi
Y
Nozaki
Kyoko
K
D002248:Carbon Monoxide / Q000737:chemistry*; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D004952:Esters; D006219:Halogens / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D004852:Epoxy Compounds; D004952:Esters; D006219:Halogens; D011725:Pyridines; D002248:Carbon Monoxide; D012238:Rhodium; C023666:pyridine