title: An acute ischemic stroke secondary to sphenoid sinusitis.
abstract: Acute isolated sphenoid sinusitis is a relatively uncommon entity. Because its symptoms and clinical findings are nonspecific, it can be easily misdiagnosed. Left unrecognized and untreated, it can lead to several well-known and severe complications, including meningitis, cerebral abscess, cavernous sinus thrombosis, and epidural or subdural empyema. We report the case of a 28-year-old woman with acute sphenoid sinusitis complicated by ischemic stroke in the left caudate nucleus, lentiform nucleus, and posterior part of the internal capsule. The stroke was diagnosed on magnetic resonance imaging. Also, magnetic resonance angiography showed a narrowing of the internal carotid artery and a narrowing of the first part of the left anterior and middle cerebral arteries (A1 and M1 segments). The patient was treated with medical therapy, including antibiotics, and surgical drainage of the sphenoid sinus via an endoscopic approach. Her outcome was good, and she experienced minimal neurologic sequelae. We discuss the possible explanations for this rare complication.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Albert Michallon University Hospital, Grenoble, Cedex 09, France. Crighini@chu-grenoble.fr
authors.forename: Christian Adrien
authors.initials: CA
authors.lastname: Righini
authors.forename: Fabrice
authors.initials: F
authors.lastname: Bing
authors.forename: Pierre
authors.initials: P
authors.lastname: Bessou
authors.forename: Kamel
authors.initials: K
authors.lastname: Boubagra
authors.forename: Emile
authors.initials: E
authors.lastname: Reyt
mesh_terms: D000208:Acute Disease; D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002340:Carotid Artery Diseases; D002439:Cefotaxime / Q000627:therapeutic use; D017985:Dalteparin / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D018810:Magnetic Resonance Angiography; D015524:Sphenoid Sinusitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000925:Anticoagulants; D000998:Antiviral Agents; D005938:Glucocorticoids; D014640:Vancomycin; D003907:Dexamethasone; D002439:Cefotaxime; D017985:Dalteparin; D000212:Acyclovir