Sjögren-Larsson syndrome in two brothers: a case report.
Sjögren-Larsson syndrome is a rare autosomal recessive disorder that was originally recognized in the coexistence of congenital ichthyosis, spastic diplegia or quadriplegia and mental retardation. We recently saw two cases with characteristic features of this rare syndrome. Two brothers aged 21 and 25 years presented with triad of congenital ichthyosis, mental retardation and spastic diplegia. Magnetic resonance imaging showed demyelinating disease in one of these cases. Electrodiagnostic studies were normal in all cases.
Moghaddam
Farid Rezaei
FR
Department of Physical Medicine and Rehabilitation, Army University of Medical Sciences, 501 Hospital, Etemadzadeh Street, Western Fatemi Street, Tehran, Iran. faridrezaeimoghaddam@gmail.com
Safar
Farid
F
Asheghan
Mahsa
M
Soltani
Zahra Reza
ZR
Zade
Fatemeh Dehghani
FD