Endometriosis: associations with menopause, hormone replacement therapy and cancer.
Endometriosis is an estrogen-dependent condition and is characterized by the presence of ectopic endometrial tissue. The pathogenesis of this condition remains an enigma. Endometriosis has well known associations with menopause both in terms of secondary outcomes from medical and surgical therapy in premenopausal women, as well as a natural occurrence/recurrence of the disease in women going through menopause naturally. This review article aims to discuss the current day modalities of management of endometriosis with their pros and cons especially in the context of menopause and cancer.
Palep-Singh
Manisha
M
Department of Gynaecology, Saint Mary's University Hospital, CMMC NHS Trust, Hathersage Road, Manchester M13 0JH, UK. Manisha.Palep-Singh@cmft.nhs.uk
Gupta
Sujata
S
D004715:Endometriosis / Q000150:complications / Q000628:therapy*; D005260:Female; D005833:Genital Neoplasms, Female / Q000209:etiology*; D020249:Hormone Replacement Therapy; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010052:Ovariectomy; D017698:Postmenopause; D017697:Premenopause