title: Hyperechoic congenital lung lesions in a non-selected population: from prenatal detection till perinatal management.
abstract: OBJECTIVE
  To present longitudinal observations of hyperechoic lung lesions (HLL) in a non-selected population from the time of prenatal diagnosis by ultrasound (US) until postnatal surgery.
  
  
  METHODS
  We conducted a retrospective study of all fetuses diagnosed with an HLL between 1990 and 2005 in our Fetal Medicine Unit.
  
  
  RESULTS
  We observed 21 cases of HLL. Among the 17 fetuses with unilateral lesion, two cyst punctures were attempted on fetuses with signs of fetal compromise. Termination of pregnancy (TOP) was performed on seven fetuses. Fourteen fetuses were followed till birth. First Chest X-ray was abnormal in ten cases, while delayed CT scans revealed a lung lesion in 12 cases. Two neonates required emergency surgery and died post operatively. Surgery was successfully performed in all other cases (n = 10). Pathological examination revealed congenital high airway obstruction syndrome, CHAOS (n = 4), lower airway stenosis (n = 2), bronchogenic cyst (n = 1), congenital lobar emphysema (n = 1), and congenital cystic adenomatoid malformation, CCAM (n = 11) including two cases associated with a sequestration.
  
  
  CONCLUSIONS
  HLL cover a wide spectrum of lung abnormalities of various severities. Post natal management should always include an early chest X-ray and CT scan to allow appropriate selection for surgery.
authors.affiliation: CHU Clermont-Ferrand, Department of Pediatric Pulmonology, 63003 Clermont-Ferrand Cedex, France.
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Lecomte
authors.forename: Hélène
authors.initials: H
authors.lastname: Hadden
authors.forename: Karen
authors.initials: K
authors.lastname: Coste
authors.forename: Denis
authors.initials: D
authors.lastname: Gallot
authors.forename: Hélène
authors.initials: H
authors.lastname: Laurichesse
authors.forename: Didier
authors.initials: D
authors.lastname: Lemery
authors.forename: Thierry
authors.initials: T
authors.lastname: Scheye
authors.forename: Pierre
authors.initials: P
authors.lastname: Dechelotte
authors.forename: André
authors.initials: A
authors.lastname: Labbé
mesh_terms: D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D008168:Lung / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal