Evaluation of sentinel lymph nodes for melanoma metastases by pathologists.
The pathologic evaluation of sentinel lymph nodes for melanoma metastases is not without significant challenges. It is affected by significant variation in approaches, which may compromise the final interpretation, leading to nonrepresentative spurious results. This article discusses various approaches along with recommended dos and don'ts for optimum evaluation of sentinel lymph nodes for melanoma metastases.
Shidham
Vinod B
VB
Department of Pathology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007432:Intraoperative Period; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery
D014408:Biomarkers, Tumor