[Protective effect of melatonin on behavioral and morphological disturbances induced by cerebrocranial trauma in different daytime in rats].
Chronic administration of the pineal hormone melatonin improves the cognitive activity and stimulates locomotion in rats, the effect being more pronounced in evening hours. On the background of melatonin action, local cerebrocranial trauma produces less pronounced behavioral and morphological disturbances, which more rapidly disappear after brain injury in the evening. The protective effect of the hormone is less pronounced in the morning hours.
Arushanian
E B
EB
Naumov
S S
SS
Ponomareva
V A
VA
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001930:Brain Injuries / Q000517:prevention & control*; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D008124:Locomotion / Q000187:drug effects*; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D051381:Rats
D002492:Central Nervous System Depressants; D008550:Melatonin