title: Synthesis and stereochemical determination of batzelladine C methyl ester.
abstract: Batzelladine C (3) is a tricyclic guanidine alkaloid of unknown stereochemistry at one centre as well as unknown absolute stereochemistry. The two possible diastereoisomers of the methyl ester corresponding to this compound have been synthesised, permitting the relative and absolute stereochemistry of this compound to be assigned.
authors.affiliation: AstraZeneca Process R&D Avlon/Charnwood, Avlon Works, Severn Road, Hallen, Bristol BS10 7ZE, UK.
authors.forename: Michael
authors.initials: M
authors.lastname: Butters
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Davies
authors.forename: Mark C
authors.initials: MC
authors.lastname: Elliott
authors.forename: Joseph
authors.initials: J
authors.lastname: Hill-Cousins
authors.forename: Benson M
authors.initials: BM
authors.lastname: Kariuki
authors.forename: Li-ling
authors.initials: LL
authors.lastname: Ooi
authors.forename: John L
authors.initials: JL
authors.lastname: Wood
authors.forename: Stuart V
authors.initials: SV
authors.lastname: Wordingham
mesh_terms: D018360:Crystallography, X-Ray; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry*; D006146:Guanidines / Q000138:chemical synthesis* / Q000737:chemistry*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D004952:Esters; D006146:Guanidines; D006575:Heterocyclic Compounds, 3-Ring; C546991:batzelladine C methyl ester