title: The structure of N,N'-bis(2-hydroxyethyl)ethane-1,2-diamine and its complexes with Zn(II) and Cd(II).
abstract: The crystal structure of the nitrate salt of N,N'-bis(2-hydroxyethyl)-ethane-1,2-diamine (BHEEN), and its complex with Zn(II) and Cd(II) are reported. (H(2)BHEEN)(NO(3))(2) packs in a layered structure with a herringbone pattern within each layer arising from H-bonding between amino and alcohol protons and NO(3)(-) counterions. In [Zn(BHEEN)(2)]Cl(2), each ligand coordinates to Zn(II) through its two N-donors producing a distorted tetrahedral geometry at the metal centre. The two hydroxyethyl arms of each ligand are trans to each other and the crystals obtained contained a racemic mixture of the bis-trans-R,R and the bis-trans-S,S isomers. All four hydroxyl groups are H-bonded to chloride counter ions, creating a layered structure. Whilst distant from the metal ion (average 3.00 A), the four O atoms of the pendent hydroxylamino groups appear positioned to interact with the metal. The orientation of the arms is preserved in a B3LYP gas phase calculation of the structure. An analysis using Bader's Atoms in Molecules indicates that the Zn-N bonds are predominantly ionic with some covalent character and that there is a weak interaction between the metal and the hydroxyl groups. Several other weak interactions including four O...HN, five O...HC and a H-H dihydrogen bond were identified. The Cd(II) complex of BHEEN crystallised as a dimer [(mu-Cl)(2)(Cd(BHEEN)Cl)(2))] with two asymmetrically-bound bridging Cl(-) ligands and a terminally-coordinated Cl(-) on each metal ion. One hydroxyl group of each ligand is coordinated to the metal and the uncoordinated hydroxyl group is H-bonded to the H atom of the coordinated hydroxyl group of the second ligand in the complex. The ESI-MS spectrum shows the presence of di-cadmium complexes, but the most intense peaks are due to mono-cadmium complexes. The gas phase B3LYP structure of the dimer energy-minimises into two monomers and the longer bond between Cd(II) and bridging Cl(-) breaks. Hence, dimerisation may be a consequence of the crystallisation process and the dimer may not be the predominant species in solution.
authors.affiliation: Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, 2050, South Africa. alvaro.desousa@wits.ac.za
authors.forename: Alvaro S
authors.initials: AS
authors.lastname: de Sousa
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Reisinger
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Fernandes
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Perry
authors.forename: Pradeep R
authors.initials: PR
authors.lastname: Varadwaj
authors.forename: Helder M
authors.initials: HM
authors.lastname: Marques
mesh_terms: D002104:Cadmium / Q000737:chemistry*; D003460:Crystallization; D003959:Diamines / Q000737:chemistry*; D019281:Dimerization; D006860:Hydrogen Bonding; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D015032:Zinc / Q000737:chemistry*
chemical_list: D003959:Diamines; D008024:Ligands; D009942:Organometallic Compounds; D002104:Cadmium; D015032:Zinc