Case of mistaken identity: bullous congenital ichthyosiform erythroderma mistaken as epidermolysis bullosa simplex.
Distinguishing clinically similar dermatologic disorders can be challenging and the differential diagnosis of a blistering eruption in the newborn period can be extensive. Several genodermatosis, such as bullous congenital ichthyosiform erythroderma (BCIE) and epidermolysis bullosa simplex (EBS), autoimmune bullous disorders, infectious diseases, sucking blisters, and bullous mastocytosis must be considered. We present a case of BCIE misdiagnosed as EBS and review characteristic clinical and histopathological features of each disorder as well as the basic approach to treatment.
Alikhan
Ali
A
University of California Davis, School of Medicine, Sacramento, California, USA.
Farshidi
Dina
D
Shwayder
Tor
T
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001452:Balneology; D001706:Biopsy; D015362:Child Nutrition Disorders / Q000150:complications / Q000628:therapy; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003951:Diagnostic Errors; D004203:Disinfection; D004643:Emollients / Q000627:therapeutic use; D004750:Enteral Nutrition; D016110:Epidermolysis Bullosa Simplex / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D005183:Failure to Thrive / Q000209:etiology; D006801:Humans; D017488:Hyperkeratosis, Epidermolytic / Q000175:diagnosis* / Q000473:pathology; D007382:Intermediate Filaments / Q000648:ultrastructure; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008854:Microscopy, Electron; D013207:Staphylococcal Skin Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy
D000900:Anti-Bacterial Agents; D004643:Emollients