title: In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa.
abstract: In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested.
authors.affiliation: Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Chachanidze
authors.forename: Aixa
authors.initials: A
authors.lastname: Curbelo-Irizarry
authors.forename: Deborah
authors.initials: D
authors.lastname: Ashcraft
authors.forename: George
authors.initials: G
authors.lastname: Pankey