HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.
HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.
Khurana
Surender
S
Division of Viral Products, Center for Biologics Evaluation and Research, FDA, 8800 Rockville Pike, Bethesda, MD 20892, USA.
Norris
Philip J
PJ
Busch
Michael P
MP
Haynes
Barton F
BF
Park
Susan
S
Sasono
Pretty
P
Mlisana
Koleka
K
Salim
Abdool Karim
AK
Hecht
Frederick M
FM
Mulenga
Joseph
J
Chomba
Elwyn
E
Hunter
Eric
E
Allen
Susan
S
Nemo
George
G
Rodriguez-Chavez
Isaac R
IR
Margolick
Joseph B
JB
Golding
Hana
H
D000914:Antibodies, Viral / Q000097:blood*; D005260:Female; D015658:HIV Infections / Q000175:diagnosis*; D006679:HIV Seropositivity; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D008297:Male; D012680:Sensitivity and Specificity
D000914:Antibodies, Viral