title: [Analysis of predictive tools for further axillary involvement in patients with sentinel-lymph-node-positive, small (< or =15 mm) invasive breast cancer].
abstract: Small breast cancers often require different treatment than larger ones. The frequency and predictability of further nodal involvement was evaluated in patients with positive sentinel lymph nodes and breast cancers < or =15 mm by means of 8 different predictive tools. Of 506 patients with such small tumors 138 with positive sentinel nodes underwent axillary dissection and 39 of these had non-sentinel node involvement too. The Stanford nomogram and the micrometastatic nomogram were the predictive tools identifying a small group of patients with low probability of further axillary involvement that might not require completion axillary lymph node dissection. Our data also suggest that the Tenon score can separate subsets of patients with a low and a higher risk of non-sentinel node metastasis. Predictive tools based on multivariate models can help in omitting completion axillary dissection in patients with low risk of non-sentinel lymph node metastasis based on their small tumor size.
authors.affiliation: Bács-Kiskun Megyei Onkormányzat Kórháza Patológiai Osztály Kecskemét Nyíri út 38. 6000.
authors.forename: Gábor
authors.initials: G
authors.lastname: Cserni
authors.forename: Rita
authors.initials: R
authors.lastname: Bori
authors.forename: István
authors.initials: I
authors.lastname: Sejben
authors.forename: Gábor
authors.initials: G
authors.lastname: Boross
authors.forename: Róbert
authors.initials: R
authors.lastname: Maráz
authors.forename: Mihály
authors.initials: M
authors.lastname: Svébis
authors.forename: Mária
authors.initials: M
authors.lastname: Rajtár
authors.forename: Eliza
authors.initials: E
authors.lastname: Tekle Wolde
authors.forename: Eva
authors.initials: E
authors.lastname: Ambrózay
mesh_terms: D000328:Adult; D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D049451:Nomograms; D011237:Predictive Value of Tests; D021701:Sentinel Lymph Node Biopsy