title: The UCSC Genome Browser database: update 2010.
abstract: The University of California, Santa Cruz (UCSC) Genome Browser website (http://genome.ucsc.edu/) provides a large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users' own annotation data. As of September 2009, genomic sequence and a basic set of annotation 'tracks' are provided for 47 organisms, including 14 mammals, 10 non-mammal vertebrates, 3 invertebrate deuterostomes, 13 insects, 6 worms and a yeast. New data highlights this year include an updated human genome browser, a 44-species multiple sequence alignment track, improved variation and phenotype tracks and 16 new genome-wide ENCODE tracks. New features include drag-and-zoom navigation, a Wiki track for user-added annotations, new custom track formats for large datasets (bigBed and bigWig), a new multiple alignment output tool, links to variation and protein structure tools, in silico PCR utility enhancements, and improved track configuration tools.
authors.affiliation: Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA. rhead@soe.ucsc.edu
authors.forename: Brooke
authors.initials: B
authors.lastname: Rhead
authors.forename: Donna
authors.initials: D
authors.lastname: Karolchik
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kuhn
authors.forename: Angie S
authors.initials: AS
authors.lastname: Hinrichs
authors.forename: Ann S
authors.initials: AS
authors.lastname: Zweig
authors.forename: Pauline A
authors.initials: PA
authors.lastname: Fujita
authors.forename: Mark
authors.initials: M
authors.lastname: Diekhans
authors.forename: Kayla E
authors.initials: KE
authors.lastname: Smith
authors.forename: Kate R
authors.initials: KR
authors.lastname: Rosenbloom
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Raney
authors.forename: Andy
authors.initials: A
authors.lastname: Pohl
authors.forename: Michael
authors.initials: M
authors.lastname: Pheasant
authors.forename: Laurence R
authors.initials: LR
authors.lastname: Meyer
authors.forename: Katrina
authors.initials: K
authors.lastname: Learned
authors.forename: Fan
authors.initials: F
authors.lastname: Hsu
authors.forename: Jennifer
authors.initials: J
authors.lastname: Hillman-Jackson
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Harte
authors.forename: Belinda
authors.initials: B
authors.lastname: Giardine
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Dreszer
authors.forename: Hiram
authors.initials: H
authors.lastname: Clawson
authors.forename: Galt P
authors.initials: GP
authors.lastname: Barber
authors.forename: David
authors.initials: D
authors.lastname: Haussler
authors.forename: W James
authors.initials: WJ
authors.lastname: Kent
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D014644:Genetic Variation; D016678:Genome; D016681:Genome, Fungal; D023281:Genomics; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D007448:Invertebrates; D008958:Models, Molecular; D010641:Phenotype; D012984:Software