An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes.
An efficient and practical method for the synthesis of indolyl-nitroalkane derivatives catalyzed by N-bromosuccinimide is described. The generality of this method was demonstrated by synthesizing an array of diverse 3-substituted indole derivatives by the reaction of different beta-nitrostyrenes with various substituted indoles. Simple reaction conditions accompanied by good yields of indolyl-nitroalkanes are the merits of this methodology.
Kuo
Chun-Wei
CW
Department of Chemistry, National Taiwan Normal University, 88, Sec. 4, Tingchow Road, Taipei 116, Taiwan.
Wang
Chun-Chao
CC
Fang
Hu-Lin
HL
Raju
B Rama
BR
Kavala
Veerababurao
V
Habib
Pateliya Mujjamil
PM
Yao
Ching-Fa
CF
D000473:Alkanes / Q000138:chemical synthesis*; D001974:Bromosuccinimide / Q000737:chemistry*; D002384:Catalysis; D026121:Indole Alkaloids / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis*
D000473:Alkanes; D026121:Indole Alkaloids; D007211:Indoles; D001974:Bromosuccinimide