title: Physical and chemical properties of superparamagnetic Fe-incorporated nano hydroxyapatite.
abstract: Nano hydroxyapatite (n-HA) crystals carrying incorporated Fe ions were designed and synthesized by a co-precipitation method. The microstructure and morphology as well as magnetic property of the Fe-incorporated n-HA crystals (denoted as n-Fe-HA) were characterized by TEM, XRD and VSM. The results showed that lattice substitution or incorporation had occurred between Fe ions and n-HA, which was quite different from the mechanical mixture of Fe3O4 nanoparticles and n-HA crystals. The n-Fe-HA with a synthetic molar ratio of 1:2 (calculated by Fe3O4:HA) exhibited a needle like crystal shape and relatively good crystallinity. However, when the molar ratio was up to 1:1, some Fe3O4 nanoparticles were separated from n-Fe-HA crystals. The magnetization measurements showed that n-Fe-HA crystals were in superparamagnetic state, proving that the existence of Fe ions in n-HA crystals contributed to the magnetic properties of n-Fe-HA crystals. As one component of biomedical composite, n-Fe-HA has a potential to promote bone regeneration.
authors.affiliation: Research Center for Nano Biomaterials, Analytical and Testing Center Sichuan University, Chengdu 610064, PR China.
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.forename: Yubao
authors.initials: Y
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Zuo
authors.forename: Weihu
authors.initials: W
authors.lastname: Yang
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Jidong
authors.initials: J
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Qin
authors.initials: Q
authors.lastname: Zou
authors.forename: Lin
authors.initials: L
authors.lastname: Cheng
authors.forename: Junfeng
authors.initials: J
authors.lastname: Li
mesh_terms: D003460:Crystallization / Q000379:methods*; D017886:Durapatite / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008280:Magnetics; D008422:Materials Testing; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D046911:Macromolecular Substances; D017886:Durapatite; D007501:Iron