Day-surgery patients anesthetized with propofol have less postoperative pain than those anesthetized with sevoflurane.
BACKGROUND
There have been recent studies suggesting that patients anesthetized with propofol have less postoperative pain compared with patients anesthetized with volatile anesthetics.


METHODS
In this randomized, double-blind study, 80 patients undergoing day-case diagnostic laparoscopic gynecological surgery were either anesthetized with IV propofol or sevoflurane. The primary outcome measured was pain on a visual analog scale.


RESULTS
Patients anesthetized with propofol had less pain compared with patients anesthetized with sevoflurane (P = 0.01). There was no difference in any of the other measured clinical outcomes.


CONCLUSIONS
The patients anesthetized with propofol appeared to have less pain than patients anesthetized with sevoflurane.
Tan
Terry
T
Department of Anaesthesia and Perioperative Medicine, Coombe Women and Infants University Hospital, Cork St., Dublin 8, Ireland. tutan@me.com
Bhinder
Rajesh
R
Carey
Michael
M
Briggs
Liam
L
D000328:Adult; D015760:Alfentanil / Q000627:therapeutic use; D000556:Ambulatory Surgical Procedures / Q000379:methods*; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008738:Methyl Ethers; D016343:Monitoring, Intraoperative; D009020:Morphine / Q000008:administration & dosage / Q000627:therapeutic use; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy / Q000453:epidemiology*; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology; D015742:Propofol; D011446:Prospective Studies; D000077149:Sevoflurane
D000701:Analgesics, Opioid; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000894:Anti-Inflammatory Agents, Non-Steroidal; D008738:Methyl Ethers; D015760:Alfentanil; D000077149:Sevoflurane; D009020:Morphine; D015742:Propofol