Nuclear magnetic resonance approaches to the rationalization of chromatographic enantiorecognition processes.
NMR spectroscopy represents a valuable tool for obtaining information about structure and dynamics at a molecular level on the diastereoisomeric complexes formed by enantiomeric substrates and chromatographic chiral selectors or modifiers. Some examples collected from the literature show the potentialities of solution NMR spectroscopy in the rationalization of chromatographic enantiorecognition processes and the different NMR approaches needed according to the chiral selector features.
Uccello-Barretta
Gloria
G
Università degli Studi di Pisa, Dipartimento di Chimica e Chimica Industriale, Via Risorgimento 35, I-56126 Pisa, Italy. gub@dcci.unipi.it
Vanni
Letizia
L
Balzano
Federica
F
D002845:Chromatography / Q000379:methods*; D003505:Cyclodextrins / Q000737:chemistry / Q000302:isolation & purification; D008823:Micelles; D008958:Models, Molecular; D054802:Molecular Imprinting; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism
D003505:Cyclodextrins; D008823:Micelles; D011134:Polysaccharides