Candida rugosa: a distinctive emerging cause of candidaemia. A case report and review of the literature.
Candida rugosa is a rare cause of candidaemia, but important to recognize because of frequent azole-resistance and its association with catheters and total parenteral nutrition. Recommended therapy is an echinocandin or amphotericin, and catheter discontinuation. Fluconazole might be substituted based on susceptibility testing and a clinical response to initial therapy.
Minces
Lucio R
LR
Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. mincesL2@upmc.edu
Ho
Ken S
KS
Veldkamp
Peter J
PJ
Clancy
Cornelius J
CJ
D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology*; D002408:Catheters, Indwelling / Q000382:microbiology; D003424:Crohn Disease; D015725:Fluconazole / Q000494:pharmacology / Q000627:therapeutic use; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016896:Treatment Outcome
D000935:Antifungal Agents; D015725:Fluconazole