title: Non-Rotavirus infection causing apnea in a neonate.
abstract: Apnea in a premature infant is not always due to immaturity and caffeine is not always the answer. We report a case of apnea in a preterm infant who presented at two weeks of life with increase in frequency of apnea that did not respond to caffeine. Family history was significant for diarrhea in a sibling. Stool PCR was positive for Norovirus Genogroup II. Enteric isolation was instituted and the apnea resolved spontaneously with conservative management. Re-emergence of apnea or persistent apnea necessitates further investigation to elucidate the etiology.
authors.affiliation: Department of Pediatrics, University of Calgary & Peter Lougheed Hospital, AB, Canada. Majeeda.Kamaluddeen@CalgaryHealthRegion.ca
authors.forename: Majeeda
authors.initials: M
authors.lastname: Kamaluddeen
authors.forename: Abhay
authors.initials: A
authors.lastname: Lodha
authors.forename: Albert
authors.initials: A
authors.lastname: Akierman
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D001049:Apnea / Q000188:drug therapy / Q000209:etiology*; D004279:DNA, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D005759:Gastroenteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D008297:Male; D029322:Norovirus / Q000302:isolation & purification*; D011247:Pregnancy; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral