title: Abnormal fluorine-18-fluorodeoxyglucose uptake in benign esophageal leiomyoma.
abstract: A benign esophageal leiomyoma with abnormally increased fluorine-18-fluorodeoxyglucose uptake on positron emission tomography (PET) was resected thoracoscopically. The tumor, of which the maximum standardized uptake value of the lesion was 4.7, was well defined and 38 mm in diameter. Neither mitotic activity nor degeneration was found histologically; and immunoreactivity for CD34, CD117, MIB-1, and glucose transporter-1 was negative immunohistochemically. A diagnosis of gastrointestinal stromal tumor was ruled out by an oncogenic kinase gene mutation study. This case cautions against PET-dependent evaluation for malignant potential of esophageal submucosal tumors.
authors.affiliation: Department of Cancer and Thoracic Surgery, Okayama University, Shikata-cho, Japan. kmiyosh@almond.ocn.ne.jp
authors.forename: Kentaroh
authors.initials: K
authors.lastname: Miyoshi
authors.forename: Minoru
authors.initials: M
authors.lastname: Naito
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Ueno
authors.forename: Shinji
authors.initials: S
authors.lastname: Hato
authors.forename: Hideo
authors.initials: H
authors.lastname: Ino
mesh_terms: D003937:Diagnosis, Differential; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013906:Thoracoscopy; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18