title: Efficacy of a bioactive glass-ceramic (Biosilicate) in the maintenance of alveolar ridges and in osseointegration of titanium implants.
abstract: OBJECTIVE
  The aims of this research were to evaluate the efficacy of a bioactive glass-ceramic (Biosilicate) and a bioactive glass (Biogran) placed in dental sockets in the maintenance of alveolar ridge and in the osseointegration of Ti implants.
  
  
  METHODS
  Six dogs had their low premolars extracted and the sockets were implanted with Biosilicate, Biogran particles, or left untreated. After the extractions, measurements of width and height on the alveolar ridge were taken. After 12 weeks a new surgery was performed to take the final ridge measurements and to insert bilaterally three Ti implants in biomaterial-implanted and control sites. Eight weeks post-Ti implant placement block biopsies were processed for histological and histomorphometric analysis. The percentages of bone-implant contact (BIC), of mineralized bone area between threads (BABT), and of mineralized bone area within the mirror area (BAMA) were determined.
  
  
  RESULTS
  The presence of Biosilicate or Biogran particles preserved alveolar ridge height without affecting its width. No significant differences in terms of BIC, BAMA, and BABT values were detected among Biosilicate, Biogran, and the non-implanted group.
  
  
  CONCLUSIONS
  The results of the present study indicate that filling of sockets with either Biosilicate or Biogran particles preserves alveolar bone ridge height and allows osseointegration of Ti implants.
authors.affiliation: Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
authors.forename: Virgílio M
authors.initials: VM
authors.lastname: Roriz
authors.forename: Adalberto L
authors.initials: AL
authors.lastname: Rosa
authors.forename: Oscar
authors.initials: O
authors.lastname: Peitl
authors.forename: Edgar D
authors.initials: ED
authors.lastname: Zanotto
authors.forename: Heitor
authors.initials: H
authors.lastname: Panzeri
authors.forename: Paulo T
authors.initials: PT
authors.lastname: de Oliveira
mesh_terms: D000539:Alveolar Process / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D002516:Ceramics; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D004285:Dogs; D005898:Glass; D016348:Osseointegration / Q000187:drug effects*; D014025:Titanium; D020390:Tooth Socket / Q000601:surgery
chemical_list: D001672:Biocompatible Materials; C073544:Biogran; D015921:Dental Implants; D014025:Titanium