Preparation of novel organovermiculites with antibacterial activity using chlorhexidine diacetate.
The novel antibacterial organovermiculites with different mass ratios of chlorhexidine diacetate (CA) were successfully prepared by ion exchange reactions. The resultant organovermiculites were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and thermal properties of prepared organovermiculites were investigated by simultaneous thermogravimetry (TG) and differential thermal analysis (DTA). The antibacterial activity of prepared organovermiculites against Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa was evaluated by finding minimum inhibitory concentration (MIC). Antibacterial studies showed that the organovermiculites strongly inhibited the growth of variety of microorganisms.
Holesová
Sylva
S
Nanotechnology Centre, VSB-Technical University of Ostrava, 17.listopadu 15/2172, 708 33 Ostrava-Poruba, Czech Republic. sylva.holesova@vsb.cz
Valásková
Marta
M
Plevová
Eva
E
Pazdziora
Erich
E
Matejová
Katerina
K
D000538:Aluminum Silicates / Q000737:chemistry* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002710:Chlorhexidine / Q000737:chemistry* / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D014961:X-Ray Diffraction
D000538:Aluminum Silicates; D000900:Anti-Bacterial Agents; C003760:vermiculite; D002710:Chlorhexidine