title: The changing trend of diverticular disease in a developing nation.
abstract: OBJECTIVE
  Left-sided diverticular disease (LDD) is associated with reduced dietary intake, whereas right-sided diverticular disease (RDD) is more common amongst Oriental populations. We aimed to determine whether the prevalence, site and distribution of diverticular disease in our Oriental population has changed over the past two decades.
  
  
  METHODS
  A total of 1663 barium enema studies performed between January 2001 and August 2002 were reviewed retrospectively. The site of disease was correlated with age, gender and ethnicity of the patient.
  
  
  RESULTS
  Forty-five per cent of patients in the study population had diverticular disease. Older patients were more likely to have LDD, whereas the Chinese ethnic group was more likely to have RDD. Right-sided diverticular disease peaks at in the sixth decade, while for LDD this occurred in the seventh and eighth decades. Right-sided diverticular disease was more common in all age groups overall. When compared with two barium enema studies carried out in Singapore two decades earlier, there was a statistically significant increase in the incidence of RDD and LDD.
  
  
  CONCLUSIONS
  There is a positive association of RDD and LDD with Chinese race and increasing age. There is an increasing incidence of both LDD and RDD compared with two decades previously.
authors.affiliation: Department of General Surgery, Tan Tock Seng Hospital, Singapore. fongss@gmail.com
authors.forename: S S
authors.initials: SS
authors.lastname: Fong
authors.forename: E Y
authors.initials: EY
authors.lastname: Tan
authors.forename: A
authors.initials: A
authors.lastname: Foo
authors.forename: R
authors.initials: R
authors.lastname: Sim
authors.forename: D M O
authors.initials: DM
authors.lastname: Cheong
mesh_terms: D000367:Age Factors; D000704:Analysis of Variance; D044466:Asian People / Q000706:statistics & numerical data*; D001466:Barium Sulfate; D002432:Cecum / Q000473:pathology*; D016009:Chi-Square Distribution; D003106:Colon / Q000473:pathology*; D003906:Developing Countries / Q000706:statistics & numerical data*; D043963:Diverticulosis, Colonic / Q000453:epidemiology*; D004241:Diverticulum, Colon / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D004733:Enema; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012846:Singapore / Q000453:epidemiology
chemical_list: D001466:Barium Sulfate