Multiresidue analysis of pesticides in soil by high-performance liquid chromatography with tandem mass spectrometry.
An analytical multiresidue method using HPLC/MS/MS with a triple-quadrupole mass spectrometer in the multiple reaction monitoring mode for the simultaneous determination of 54 pesticides in soil has been developed. The procedure involved initial single-phase extraction of soil sample with acetonitrile by sonication, followed by liquid-liquid partitioning after addition of NaCI. The average recovery by the HPLC/MS/MS method obtained for these compounds varied from 63.2 to 113.8%, with an RSD between 1.9 and 7.1%. The method gave good linearity over the assay range of 10-500 microg/L (except famoxadone, 50-1000 microg/L); the LOD and LOQ for the pesticides varied from 0.02 to 13.2 and from 0.1 to 43.9 microg/kg, respectively. The proposed method was used to determine pesticide levels in soil samples from two experimental vineyards and two tomato greenhouses.
Fenoll
José
J
Instituto Murciano de Investigación y Desarrollo Agrario y Alimentario, IMIDA, C/Mayor s/n, La Alberca 30150 Murcia, Spain. jose.fenoll@carm.es
Hellín
Pilar
P
Martínez
Carmen M
CM
Flores
Pilar
P
D000383:Agriculture / Q000379:methods; D002138:Calibration; D002623:Chemistry Techniques, Analytical; D002713:Chlorine / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D012965:Sodium Chloride / Q000737:chemistry; D012987:Soil; D012989:Soil Pollutants / Q000032:analysis*; D012997:Solvents; D013010:Sonication
D010573:Pesticide Residues; D010575:Pesticides; D012987:Soil; D012989:Soil Pollutants; D012997:Solvents; D012965:Sodium Chloride; D002713:Chlorine