title: Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds.
abstract: Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.
authors.affiliation: Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
authors.forename: Junichiro
authors.initials: J
authors.lastname: Shimizu
authors.forename: Kyohei
authors.initials: K
authors.lastname: Mochida
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kitamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Miori
authors.initials: M
authors.lastname: Kishimoto
authors.forename: Ki-Ja
authors.initials: KJ
authors.lastname: Lee
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Yoh-Ichi
authors.initials: Y
authors.lastname: Miyake
authors.forename: Masanari
authors.initials: M
authors.lastname: Nakayama
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Yamada
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000378:metabolism / Q000473:pathology*; D004285:Dogs; D005260:Female; D007249:Inflammation / Q000378:metabolism / Q000662:veterinary*; D007405:Intervertebral Disc Displacement / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D008297:Male