title: Free radical scavenging abilities of flavonyl-thiazolidine-2,4-dione compounds.
abstract: Free radical scavenging activity of flavonyl-thiazolidine-2,4-dione compounds has been evaluated using chemiluminescence, electron spin resonance spectroscopy with 5,5-dimethyl-1-pyrroline-1-oxide as spin trap and DPPH (2,2'-diphenyl-1-picrylhydrazyl) method. The examined compounds exhibited 28-50% scavenging superoxide anion radical O₂⁻ⁱ16.7-76.7% hydroxyl radical (HO•) and 9-40% DPPH radical. Compounds containing carbonyl group in their structure can be considered as antioxidants with high relevance and great biological importance.
authors.affiliation: Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Tandoğan, Ankara, Turkey.
authors.forename: Oya
authors.initials: O
authors.lastname: Bozdağ-Dündar
authors.forename: Rahmiye
authors.initials: R
authors.lastname: Ertan
authors.forename: Hassan Y
authors.initials: HY
authors.lastname: Aboul-Enein
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Kładna
authors.forename: Irena
authors.initials: I
authors.lastname: Kruk
mesh_terms: D047309:Flavones / Q000737:chemistry*; D016166:Free Radical Scavengers; D049449:Luminescence; D015394:Molecular Structure; D045162:Thiazolidinediones / Q000737:chemistry*
chemical_list: D047309:Flavones; D016166:Free Radical Scavengers; D045162:Thiazolidinediones; C500090:thiazolidine-2,4-dione