Jenner's irony: cowpox taps into T cell evasion.
CPXV12 is the first poxvirus gene product demonstrated to inhibit the transporter associated with antigen processing (TAP). This cowpox virus function acts in concert with a second gene product, CPXV203, to efficiently suppress MHC class I antigen presentation and enhance in vivo virulence.
Wilkinson
Gavin W G
GW
Section of Medical Microbiology, Cardiff University, Cardiff CF14 4XX, UK. wilkinsongw1@cf.ac.uk
Lehner
Paul J
PJ