title: Association of malnutrition with amebiasis.
abstract: Observation of a cohort of preschool children in Dhaka, Bangladesh, is beginning to reveal the contributions of environment, host, and parasite to amebiasis. Reviewed here are the associations and interactions of malnutrition, IgA and interferon-gamma, human leukocyte antigen alleles, and parasite genotypes to the outcome of infection. Future efforts aimed at understanding the mechanisms of these effects are described.
authors.affiliation: Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA. wap3g@virginia.edu
authors.forename: William A
authors.initials: WA
authors.lastname: Petri
authors.forename: Dinesh
authors.initials: D
authors.lastname: Mondal
authors.forename: Kristine M
authors.initials: KM
authors.lastname: Peterson
authors.forename: Priya
authors.initials: P
authors.lastname: Duggal
authors.forename: Rashidul
authors.initials: R
authors.lastname: Haque
mesh_terms: D000483:Alleles; D000818:Animals; D001459:Bangladesh; D015362:Child Nutrition Disorders / Q000276:immunology* / Q000469:parasitology*; D002675:Child, Preschool; D004404:Dysentery, Amebic / Q000150:complications* / Q000276:immunology; D004748:Entamoeba histolytica / Q000235:genetics / Q000472:pathogenicity*; D004749:Entamoebiasis / Q000150:complications / Q000276:immunology; D005838:Genotype; D006790:Host-Parasite Interactions; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007371:Interferon-gamma / Q000097:blood
chemical_list: D007070:Immunoglobulin A; D007371:Interferon-gamma