title: Use of allograft bone for posterior C1-2 fusion.
abstract: OBJECTIVE
  An iliac crest autograft is the gold standard for bone grafting in posterior atlantoaxial arthrodesis but can be associated with significant donor-site morbidity. Conversely, an allograft has historically performed suboptimally for atlantoaxial arthrodesis as an onlay graft. The authors have modified a bone grafting technique to allow placement of a bicortical iliac crest allograft in an interpositional manner, and they evaluated it as an alternative to an autograft in posterior atlantoaxial arthrodesis.
  
  
  METHODS
  The records of 89 consecutive patients in whom C1-2 arthrodesis was performed between 2001 and 2005 were reviewed.
  
  
  RESULTS
  Forty-seven patients underwent 48 atlantoaxial arthrodeses with an allograft (mean follow-up 16.1 months, range 0-49 months), and 42 patients underwent autograft bone grafting (mean follow-up 17.6 months, range 0-61.0 months). The operative time was 50 minutes shorter in the allograft (mean 184 minutes, range 106-328 minutes) than in the autograft procedure (mean 234 minutes, range 154-358 minutes), and the estimated blood loss was 50% lower in the allograft group than in the autograft group (mean 103 ml [range 30-200 ml] vs mean 206 ml [range 50-400 ml], respectively). Bone incorporation was initially slower in the allograft than in the autograft group but equalized by 12 months postprocedure. The respective fusion rates after 24 months were 96.7 and 88.9% for autografts and allografts. Complications at the donor site occurred in 16.7% of the autograft patients, including 1 pelvic fracture, 1 retained sponge, 1 infection, 2 hernias requiring repair, 2 hematomas, and persistent pain.
  
  
  CONCLUSIONS
  The authors describe a technique for interpositional bone grafting between C-1 and C-2 that allows for the use of an allograft with excellent fusion results. This technique reduced the operative time and blood loss and eliminated donor-site morbidity.
authors.affiliation: Department of Neurosurgery, University of Utah, Salt Lake City, Utah 84132, USA.
authors.forename: Virany Huynh
authors.initials: VH
authors.lastname: Hillard
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Fassett
authors.forename: Michael A
authors.initials: MA
authors.lastname: Finn
authors.forename: Ronald I
authors.initials: RI
authors.lastname: Apfelbaum
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001268:Atlanto-Axial Joint / Q000601:surgery*; D001368:Axis, Cervical Vertebra / Q000601:surgery; D016063:Blood Loss, Surgical; D001863:Bone Screws; D016025:Bone Transplantation / Q000379:methods*; D001270:Cervical Atlas / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000601:surgery*; D013123:Spinal Fusion / Q000379:methods*; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult