title: The effect of exercise on leptin, insulin, cortisol and lipid profiles in obese children.
abstract: This prospective, randomized study investigated the effect of exercise on leptin, insulin, cortisol and lipid profiles in obese children. A total of 40 obese boys aged 10 - 12 years with a body mass index (BMI) >or= 30 kg/m(2) were randomly separated into an exercise group (n = 20) that underwent a 12-week aerobic exercise programme and a non-exercise (control) group (n = 20). The BMI, low-density lipoprotein, cortisol, leptin and insulin levels were significantly lower in the exercise group after 12 weeks compared with baseline values, whereas high-density lipoprotein levels were significantly higher. In contrast, in the control group, low-density lipoprotein, cortisol and leptin levels were significantly higher after 12 weeks compared with baseline values while high-density lipoprotein levels were significantly lower. These findings indicate the importance of regular exercise in the regulation of body weight and protection against cardiovascular risk factors in obese children.
authors.affiliation: Higher School of Physical Education and Sports, Gaziantep University, Gaziantep, Turkey. kkaracabey@hotmail.com
authors.forename: Kursat
authors.initials: K
authors.lastname: Karacabey
mesh_terms: D015992:Body Mass Index; D016022:Case-Control Studies; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005081:Exercise Therapy; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007004:Hypoglycemic Agents / Q000097:blood; D007328:Insulin / Q000097:blood*; D020738:Leptin / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008297:Male; D009765:Obesity / Q000503:physiopathology / Q000628:therapy*; D011446:Prospective Studies
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D020738:Leptin; D008055:Lipids; D006854:Hydrocortisone