Decomposing N2 NOGO wave of event-related potentials into independent components.
Inconsistencies in previous attempts to localize the N2 wave in the GO/NOGO task led to the present investigation. The inconsistencies were probably because of heterogeneity of psychological operations involved in GO/NOGO tasks. We applied the independent component analysis to a collection of individual event-related potentials in response to GO and NOGO cues in the two stimulus visual GO/NOGO task. The selected six independent components with different topographies and time courses constituted 87% of the artifact-free signal variance. Three of them were loaded into the frontally distributed N2 wave. According to standardized low-resolution electromagnetic tomography these three independent components were generated in the supplementary motor cortex, left angular gyrus and anterior cingulate cortex.
Kropotov
Juri D
JD
Institute of the Human Brain of Russian Academy of Sciences, St. Petersburg 197376, Russia. jdkropotov@yahoo.com
Ponomarev
Valery A
VA
D000293:Adolescent; D000328:Adult; D016477:Artifacts; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D003463:Cues; D004569:Electroencephalography; D005071:Evoked Potentials; D056344:Executive Function / Q000502:physiology*; D005133:Eye Movements / Q000502:physiology; D006801:Humans; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors; D014054:Tomography; D055815:Young Adult