title: Toward the synthesis of benzothiazolyl fluoroaminosulfones.
abstract: Due to the importance of allylamines in organic synthesis, the synthesis of reagents as potent precursors of aminofluoroolefins is reported from functionalized benzothiazolylsulfones. The key intermediate, a fluorovinyl sulfone, was prepared and functionalized by addition of aliphatic, aromatic amines and amino acid alkyl esters through an aza-Michael addition reaction.
authors.affiliation: Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507 & FR3038, ENSICAEN Université de Caen Basse-Normandie, 6 Bd du Maréchal Juin 14050 Caen Cedex, France.
authors.forename: Charlène
authors.initials: C
authors.lastname: Calata
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Pfund
authors.forename: Thierry
authors.initials: T
authors.lastname: Lequeux
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000499:Allylamine / Q000031:analogs & derivatives / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D001372:Aza Compounds / Q000737:chemistry; D052160:Benzothiazoles / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D008956:Models, Chemical; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D000588:Amines; D000596:Amino Acids; D001372:Aza Compounds; D052160:Benzothiazoles; D004952:Esters; D006845:Hydrocarbons, Fluorinated; D013450:Sulfones; D000499:Allylamine