A new versatile solvatochromic amino-macrocycle. From metal ions to cell sensing in solution and in the solid state.
A new fluorescent NBD-polyaza-macrocycle sensor (L) was synthesized. The coordination of Cu(ii) and Zn(ii) in acetonitrile switches on the fluorescence with different emission wavelengths. Cu(ii) complexes showed solid-state fluorescence. Both L and Cu-complex interact with human cell line (U937) highlighting the cell membrane by fluorescence microscopy.
Ambrosi
Gianluca
G
Institute of Chemical Sciences, University of Urbino, P.zza Rinascimento 6, I-61029 Urbino, Italy.
Ciattini
Samuele
S
Formica
Mauro
M
Fusi
Vieri
V
Giorgi
Luca
L
Macedi
Eleonora
E
Micheloni
Mauro
M
Paoli
Paola
P
Rossi
Patrizia
P
Zappia
Giovanni
G
D000097:Acetonitriles / Q000737:chemistry; D001372:Aza Compounds / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D007477:Ions / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D008968:Molecular Conformation; D020298:U937 Cells; D015032:Zinc / Q000737:chemistry*
D000097:Acetonitriles; D001372:Aza Compounds; D005456:Fluorescent Dyes; D007477:Ions; D047028:Macrocyclic Compounds; D003300:Copper; D015032:Zinc; C032159:acetonitrile