title: Preoperative embolization of Castleman's disease using microspheres.
abstract: Castleman's disease is a rare form of lymph node hyperplasia most commonly presenting as a solitary hypervascular mediastinal mass. Surgical resection is the treatment of choice, but this can be associated with significant blood loss due to its hypervascularity. We report two cases with a preoperative diagnosis of mediastinal Castleman's disease in whom preoperative embolization with Trisacryl gelatin microspheres (Biosphere Medical, Rockland, MA) was performed. Compared with the literature, a decrease in the amount of perioperative bleeding was noted in both cases.
authors.affiliation: Department of Radiology, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
authors.forename: Warren
authors.initials: W
authors.lastname: Swee
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Housseini
authors.forename: J Fritz
authors.initials: JF
authors.lastname: Angle
authors.forename: David R
authors.initials: DR
authors.lastname: Jones
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Daniel
authors.forename: Ulku C
authors.initials: UC
authors.lastname: Turba
authors.forename: Ehab A
authors.initials: EA
authors.lastname: Abdel-Gawad
authors.forename: Klaus D
authors.initials: KD
authors.lastname: Hagspiel
mesh_terms: D000293:Adolescent; D001027:Aortography; D001706:Biopsy; D005871:Castleman Disease / Q000175:diagnosis / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008863:Microspheres; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods*; D013908:Thoracotomy / Q000379:methods; D014057:Tomography, X-Ray Computed