Efficacy of a bioactive glass-ceramic (Biosilicate) in the maintenance of alveolar ridges and in osseointegration of titanium implants.
OBJECTIVE
The aims of this research were to evaluate the efficacy of a bioactive glass-ceramic (Biosilicate) and a bioactive glass (Biogran) placed in dental sockets in the maintenance of alveolar ridge and in the osseointegration of Ti implants.


METHODS
Six dogs had their low premolars extracted and the sockets were implanted with Biosilicate, Biogran particles, or left untreated. After the extractions, measurements of width and height on the alveolar ridge were taken. After 12 weeks a new surgery was performed to take the final ridge measurements and to insert bilaterally three Ti implants in biomaterial-implanted and control sites. Eight weeks post-Ti implant placement block biopsies were processed for histological and histomorphometric analysis. The percentages of bone-implant contact (BIC), of mineralized bone area between threads (BABT), and of mineralized bone area within the mirror area (BAMA) were determined.


RESULTS
The presence of Biosilicate or Biogran particles preserved alveolar ridge height without affecting its width. No significant differences in terms of BIC, BAMA, and BABT values were detected among Biosilicate, Biogran, and the non-implanted group.


CONCLUSIONS
The results of the present study indicate that filling of sockets with either Biosilicate or Biogran particles preserves alveolar bone ridge height and allows osseointegration of Ti implants.
Roriz
Virgílio M
VM
Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Rosa
Adalberto L
AL
Peitl
Oscar
O
Zanotto
Edgar D
ED
Panzeri
Heitor
H
de Oliveira
Paulo T
PT
D000539:Alveolar Process / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D002516:Ceramics; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D004285:Dogs; D005898:Glass; D016348:Osseointegration / Q000187:drug effects*; D014025:Titanium; D020390:Tooth Socket / Q000601:surgery
D001672:Biocompatible Materials; C073544:Biogran; D015921:Dental Implants; D014025:Titanium