title: Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrown toenails in people with diabetes.
abstract: BACKGROUND
  Treatment of ingrown toenails using chemical matricectomy in patients with diabetes has been difficult, because delayed wound healing, wound infections, and digital ischemia can interfere with the procedure. Chemical matricectomy with 10% sodium hydroxide is an effective treatment for ingrown toenails in a normal population.
  
  
  OBJECTIVE
  Investigation of the effectiveness and safety of chemical matricectomy with 10% sodium hydroxide solution for ingrown toenails in patients with diabetes.
  
  
  METHODS
  Thirty patients with diabetes with 40 ingrown toenails and 30 patients without diabetes with 41 ingrown toenails were enrolled in the study. After partial avulsion of the affected edge, germinal matrix was treated for 1 minute with 10% sodium hydroxide. Patients were observed on alternate days until complete healing was achieved and followed for up to 24 months for recurrence.
  
  
  RESULTS
  Assessment of the treatment in both groups for complete healing, postoperative pain, tissue damage, drainage, infections, and rate of recurrences revealed no statistically significant difference.
  
  
  CONCLUSIONS
  The partial avulsion of the affected edge and the treatment of the germinal matrix for 1 minute with 10% sodium hydroxide preceded by matrix curettage is an effective and safe treatment modality for ingrown toenails in people with diabetes.
authors.affiliation: Department of Dermatology, Ministry of Health, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey. semihtatlican@gmail.com
authors.forename: Semih
authors.initials: S
authors.lastname: Tatlican
authors.forename: Cemile
authors.initials: C
authors.lastname: Eren
authors.forename: Burcu
authors.initials: B
authors.lastname: Yamangokturk
authors.forename: Fatma
authors.initials: F
authors.lastname: Eskioglu
authors.forename: Seher
authors.initials: S
authors.lastname: Bostanci
mesh_terms: D000287:Administration, Topical; D000328:Adult; D002424:Caustics / Q000008:administration & dosage*; D002425:Cautery; D016009:Chi-Square Distribution; D048909:Diabetes Complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D009262:Nails / Q000601:surgery*; D009263:Nails, Ingrown / Q000601:surgery*; D010147:Pain Measurement; D055502:Secondary Prevention; D012972:Sodium Hydroxide / Q000008:administration & dosage*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D002424:Caustics; D012972:Sodium Hydroxide