Barlerisides A and B, new potent superoxide scavenging phenolic glycosides from Barleria acanthoides.
Barlerisides A (1) and B (2), new phenolic glycosides, have been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with two known compounds acteoside (3) and p-hydroxycinnamic acid (4). Their structures have been assigned on the basis of spectral studies. Both 1 and 2 showed significant activity in the superoxide scavenging assay while weak inhibitory activity was observed against the enzyme xanthine oxidase.
Karim
Aman
A
H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Noor
Atia Tun
AT
Malik
Abdul
A
Qadir
Muhammad I
MI
Choudhary
Muhammad I
MI
D027901:Acanthaceae / Q000737:chemistry*; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D012997:Solvents / Q000737:chemistry; D013481:Superoxides / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors / Q000378:metabolism
D000893:Anti-Inflammatory Agents; D047309:Flavones; D016166:Free Radical Scavengers; D005960:Glucosides; D006027:Glycosides; D010636:Phenols; D010936:Plant Extracts; D012997:Solvents; C548345:barleriside A; C548346:barleriside B; D013481:Superoxides; D014969:Xanthine Oxidase