Immune thrombocytopenia in lymphoproliferative disorders.
Lymphoproliferative disorders are recognized as a common cause of secondary immune thrombocytopenia (ITP). The mechanisms involved in the pathogenesis of ITP associated with lymphoproliferative disorders are heterogeneous and often linked to the presence and activity of the malignant clone. A better understanding of the responsible mechanisms leading to ITP in each disease may allow for targeted treatment decisions, avoiding unwarranted immunosuppression and bleeding complications.
Visco
Carlo
C
Division of Hematology, Department of Cell Therapy and Hematology, San Bortolo Hospital, Via Rodolfi 37, Vicenza 36100, Italy.
Rodeghiero
Francesco
F
D006801:Humans; D008232:Lymphoproliferative Disorders / Q000150:complications*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000209:etiology* / Q000628:therapy