Neurologic manifestations of systemic lupus erythematosus in children and adults.
Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.
Muscal
Eyal
E
Division of Pediatric Rheumatology, Texas Children's Hospital/Baylor College of Medicine, 6621 Fannin Street MC 3-2290, Houston, TX 77030, USA.
Brey
Robin L
RL
D000328:Adult; D000818:Animals; D001921:Brain / Q000473:pathology; D002648:Child; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology*; D020945:Lupus Vasculitis, Central Nervous System / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D015995:Prevalence