(11)C-PIB PET in subjective cognitive impairment.
People with Subjective Cognitive Impairment (SCI) may be at increased risk of dementia. In this study we examined amyloid load in 5 SCI subjects and 14 controls using PIB PET scanning. One SCI subject had significantly increased PIB retention in the cortical areas of interest. Larger, longitudinal studies are indicated.
Rodda
J
J
Department of Mental Health Sciences, University College London, UK. j.rodda@ucl.ac.uk
Okello
A
A
Edison
P
P
Dannhauser
T
T
Brooks
D J
DJ
Walker
Z
Z
D000368:Aged; D000682:Amyloid / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D002250:Carbon Radioisotopes; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000378:metabolism*; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000523:psychology; D003704:Dementia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000523:psychology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008568:Memory; D008875:Middle Aged; D009483:Neuropsychological Tests; D049268:Positron-Emission Tomography; D012307:Risk Factors; D006113:United Kingdom
D000682:Amyloid; D015415:Biomarkers; D002250:Carbon Radioisotopes