title: [Squamous cell carcinoma on a pleomorphic adenoma with amyloid stroma of the palate].
abstract: BACKGROUND
  Squamous cell carcinoma ex-pleomorphic adenoma (CXAP) is a malignant and rare mixed tumor. We report a new case.
  
  
  METHODS
  A seventy-year-old woman consulted for a mass in the left hemi-face having evolved over the last 20years. The physical examination revealed a hard and large tumor invading all the palate. Computed tomography revealed a heterogeneous 8.5cm long maxillary mass. The diagnosis of CXAP was made on a biopsy. A histological study confirmed the diagnosis after surgical resection of the tumor, specifying its noninvasive character.
  
  
  CONCLUSIONS
  CXAP is generally located in the parotid gland; it is very rarely located in the palate. The degenerated epithelial component generally corresponds to an adenocarcinoma or an undifferentiated carcinoma; squamous-cell carcinoma is more rarely reported. The prognosis is excellent for the micro and noninvasive types. Surgery remains the treatment of choice.
authors.affiliation: Laboratoire d'anatomie et cytologie pathologiques, CHU Habib Bourguiba, 3029 Sfax, Tunisie.
authors.forename: C
authors.initials: C
authors.lastname: Chaari
authors.forename: S
authors.initials: S
authors.lastname: Ellouze
authors.forename: H
authors.initials: H
authors.lastname: Chamli
authors.forename: S
authors.initials: S
authors.lastname: Krichen Makni
authors.forename: F
authors.initials: F
authors.lastname: Karray
authors.forename: T
authors.initials: T
authors.lastname: Sellami Boudawara
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D000682:Amyloid / Q000032:analysis*; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007633:Keratins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D015260:Neprilysin / Q000032:analysis; D010157:Palatal Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D000682:Amyloid; D007633:Keratins; D015260:Neprilysin