title: Caption: a filtration-based platelet concentration system.
abstract: Despite significant advances, wound management remains a medical challenge and a major health-expense problem. Currently, a wide range of therapeutic interventions are available for wound care. This is only partially explained by the variability in the presenting clinical situation and shows that there is no panacea for this complex medical problem. Over time, a multitude of interventions have been proposed as solutions for faster and more effective healing; however, only a few are still part of the wound care armamentarium today. Based on the fact that platelets contain a high concentration of growth factors, the application of platelet-enriched plasma over wound sites was recently introduced as a novel therapeutic modality. As increasing evidence started to validate its benefit, several devices for platelet-rich plasma preparation became available. Here, we present the most recently introduced platelet concentration system and provide insights on the current and possible future applications of this treatment modality.
authors.affiliation: Department of Surgery, The University of Toledo Health Science Campus, 3000 Arlington Avenue, Toledo, OH 43614, USA.
authors.forename: Barbu
authors.initials: B
authors.lastname: Gociman
authors.forename: Mouchammed
authors.initials: M
authors.lastname: Agko
authors.forename: Mouchammed
authors.initials: M
authors.lastname: Agk
authors.forename: Steven L
authors.initials: SL
authors.lastname: Moran
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods; D001792:Blood Platelets / Q000502:physiology*; D004864:Equipment and Supplies; D005374:Filtration / Q000295:instrumentation*; D006801:Humans; D051379:Mice; D010976:Platelet Count; D053657:Platelet-Rich Plasma; D013048:Specimen Handling; D014945:Wound Healing / Q000187:drug effects