title: WormBase: a comprehensive resource for nematode research.
abstract: WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.
authors.affiliation: Ontario Institute For Cancer Research, Toronto, ON, Canada. info@toddharris.net
authors.forename: Todd W
authors.initials: TW
authors.lastname: Harris
authors.forename: Igor
authors.initials: I
authors.lastname: Antoshechkin
authors.forename: Tamberlyn
authors.initials: T
authors.lastname: Bieri
authors.forename: Darin
authors.initials: D
authors.lastname: Blasiar
authors.forename: Juancarlos
authors.initials: J
authors.lastname: Chan
authors.forename: Wen J
authors.initials: WJ
authors.lastname: Chen
authors.forename: Norie
authors.initials: N
authors.lastname: De La Cruz
authors.forename: Paul
authors.initials: P
authors.lastname: Davis
authors.forename: Margaret
authors.initials: M
authors.lastname: Duesbury
authors.forename: Ruihua
authors.initials: R
authors.lastname: Fang
authors.forename: Jolene
authors.initials: J
authors.lastname: Fernandes
authors.forename: Michael
authors.initials: M
authors.lastname: Han
authors.forename: Ranjana
authors.initials: R
authors.lastname: Kishore
authors.forename: Raymond
authors.initials: R
authors.lastname: Lee
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Müller
authors.forename: Cecilia
authors.initials: C
authors.lastname: Nakamura
authors.forename: Philip
authors.initials: P
authors.lastname: Ozersky
authors.forename: Andrei
authors.initials: A
authors.lastname: Petcherski
authors.forename: Arun
authors.initials: A
authors.lastname: Rangarajan
authors.forename: Anthony
authors.initials: A
authors.lastname: Rogers
authors.forename: Gary
authors.initials: G
authors.lastname: Schindelman
authors.forename: Erich M
authors.initials: EM
authors.lastname: Schwarz
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Tuli
authors.forename: Kimberly
authors.initials: K
authors.lastname: Van Auken
authors.forename: Daniel
authors.initials: D
authors.lastname: Wang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Wang
authors.forename: Gary
authors.initials: G
authors.lastname: Williams
authors.forename: Karen
authors.initials: K
authors.lastname: Yook
authors.forename: Richard
authors.initials: R
authors.lastname: Durbin
authors.forename: Lincoln D
authors.initials: LD
authors.lastname: Stein
authors.forename: John
authors.initials: J
authors.lastname: Spieth
authors.forename: Paul W
authors.initials: PW
authors.lastname: Sternberg
mesh_terms: D000483:Alleles; D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000235:genetics*; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D010641:Phenotype; D017434:Protein Structure, Tertiary; D012984:Software; D014157:Transcription Factors
chemical_list: D014157:Transcription Factors