title: Rehabilitation outcomes after anoxic brain injury: a case-controlled comparison with traumatic brain injury.
abstract: OBJECTIVE
  To investigate the functional outcomes of patients with anoxic brain injury (AnBI) compared with control patients with traumatic brain injury (TBI) during inpatient rehabilitation.
  
  
  METHODS
  Matched case-controlled design.
  
  
  METHODS
  Inpatient neurorehabilitation program.
  
  
  METHODS
  Fifteen patients with AnBI and 15 patients with TBI.
  
  
  METHODS
  Data of 15 patients with a primary diagnosis of AnBI were retrospectively reviewed and matched to 15 patients with TBI admitted within the same time frame on age, acute care length of stay, and functional status at admission.
  
  
  METHODS
  Functional outcome was assessed by the use of the Functional Independence Measure (FIM).
  
  
  RESULTS
  Compared with the control patients with TBI, patients with AnBI achieved significantly lower FIM motor gain (16.3+/-15.6 versus 5.7+/-10.7, respectively) and efficiency scores (0.27+/-0.28 versus 0.06+/-0.13), discharge FIM cognition scores (25.9+/-5.9 versus 21.7+/-7.3), total FIM gain (22.5+/-19.6 versus 9.1+/-12.1), and total FIM efficiency scores (0.39+/-0.38 versus 0.10+/-0.16; all P<.05).
  
  
  CONCLUSIONS
  Results suggest a slower rate of recovery for patients with AnBI compared with TBI, with physical recovery being slower than cognitive recovery as measured by the FIM during inpatient rehabilitation when matched according to preinjury characteristics and functional status at rehabilitation admission. Future studies on larger samples of patients with AnBI and TBI that use a case-controlled design and longer-term outcome measurement are warranted to further clarify the differences in functional outcomes between these groups and to assess whether optimal rehabilitation interventions differ for these groups.
authors.affiliation: Neuro Rehabilitation Program, Toronto Rehabilitation Institute, and the Division of Physiatry, University of Toronto, Toronto, ON, Canada M5G 2A2. cullen.nora@torontorehab.on.ca
authors.forename: Nora K
authors.initials: NK
authors.lastname: Cullen
authors.forename: Charmagne
authors.initials: C
authors.lastname: Crescini
authors.forename: Mark T
authors.initials: MT
authors.lastname: Bayley
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology / Q000534:rehabilitation*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000503:physiopathology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D020127:Recovery of Function; D016896:Treatment Outcome