title: Pouchitis and pouch dysfunction.
abstract: Restorative proctocolectomy with ileal pouch-anal anastomosis has become the surgical treatment of choice for most patients with ulcerative colitis who require surgery. Although the surgical procedure offers a cure in some patients, postoperative inflammatory and noninflammatory complications are common. Pouchitis is the most common long-term complication of the procedure. Pouchitis represents a spectrum of disease processes with heterogeneous risk factors, clinical phenotypes, natural history, and prognosis. Accurate diagnosis and classification are important for proper treatment and prognosis.
authors.affiliation: Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Bo
authors.initials: B
authors.lastname: Shen
mesh_terms: D003093:Colitis, Ulcerative / Q000601:surgery*; D006801:Humans; D015994:Incidence; D019449:Pouchitis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D015995:Prevalence; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*; D012307:Risk Factors