title: [Bone loss treatment, pseudoarthrosis, arthrodesis and benign tumors using xenoimplant: clinical study].
abstract: BACKGROUND
  Bone loss as a result of arthrodesis, pseudarthrosis, benign tumors and bone defects was treated using a xenoimplant (Nukbone).
  
  
  METHODS
  The effectiveness of the material was evaluated through a longitudinal and observational study at the Hospital Regional "General Ignacio Zaragoza" (HRGIZ) ISSSTE. The Mexican xenoimplant is a patent of the National Autonomous University of Mexico (UNAM).
  
  
  RESULTS
  Fifty two patients were considered regardless of age or gender. Of these patients, 28 were male and 24 female. Average age of the patients was 47.7 years (9-84 years). Twenty eight patients had arthrodesis, 16 were treated with pseudarthrosis, three patients had benign tumors and five patients presented bone defects, which were implanted with Nukbone at the site and was the correct treatment for the problem. The xenoimplant is fully integrated during a period of 3-18 months, depending on the size of the pathology and the region where it was placed. Fracture healing was evaluated radiographically according to the classification of Montoya. No patient had clinical signs of rejection.
  
  
  CONCLUSIONS
  In Mexico, bony xenoimplants (osseous) have been used, all of foreign origin due to the high degree of technological dependence in this country. In this study we describe the use, for the first time, of a Mexican xenoimplant with a patent from the Universidad Nacional Autónoma de México (UNAM). The Mexican xenoimplant is biocompatible and can be adapted to treat pathologies where bony (osseous) material is needed.
authors.affiliation: Servicio de Ortopedia, Hospital Regional "General Ignacio Zaragoza", Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), México, D.F., Mexico. cuevaf1@hotmail.com
authors.forename: José Fernando
authors.initials: JF
authors.lastname: Cueva-Del Castillo
authors.forename: Gustavo Adolfo
authors.initials: GA
authors.lastname: Valdés-Gutiérrez
authors.forename: Francisco
authors.initials: F
authors.lastname: Elizondo-Vázquez
authors.forename: Omar
authors.initials: O
authors.lastname: Pérez-Ortiz
authors.forename: María Cristina
authors.initials: MC
authors.lastname: Piña Barba
authors.forename: Benjamín Herminio
authors.initials: BH
authors.lastname: León-Mancilla
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001174:Arthrodesis / Q000009:adverse effects; D001859:Bone Neoplasms / Q000601:surgery*; D001862:Bone Resorption / Q000601:surgery*; D016025:Bone Transplantation; D002417:Cattle; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011542:Pseudarthrosis / Q000209:etiology / Q000601:surgery*; D014183:Transplantation, Heterologous; D055815:Young Adult