title: Laser lipolysis with pulsed 1064 nm Nd:YAG laser for the treatment of gynecomastia.
abstract: BACKGROUND
  Lipolysis using laser is currently widely used for reducing localized fat. A 1064 nm neodynium-doped yttrium aluminum garnet (Nd:YAG) laser lipolysis was investigated in this study to evaluate its efficacy and safety in the treatment of gynecomastia.
  
  
  METHODS
  Five male patients diagnosed with gynecomastia were enrolled in this study, which was designed as a controlled split-breast trial. One breast of each patient was subjected to laser lipolysis and was then compared with a contralateral breast. Photographs and clinical assessments were obtained before the lipolysis, and at the fourth and eighth weeks thereafter. Computed tomography (CT) scan and ultrasound (US) imaging were used to evaluate the changes in the breasts' thicknesses.
  
  
  RESULTS
  The mean chest circumference was found to have been significantly reduced 8 weeks after the laser lipolysis. The clinical outcomes of the laser lipolysis were considered favorable by both the patients and clinicians. The CT and US scans showed that the thicknesses of the treated right breasts reduced more than those of the left breasts were 8 weeks after the laser lipolysis. The side effects (pain, edema, and ecchymosis) were minimal and disappeared shortly after they first manifested. Limitations The limitations of this study are that it employed small treatment groups and short-term follow-up.
  
  
  CONCLUSIONS
  This study demonstrated that gynecomastia can be treated effectively and safely through 1064 nm Nd:YAG laser lipolysis.
authors.affiliation: Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, South Korea.
authors.forename: Yong Kwan
authors.initials: YK
authors.lastname: Rho
authors.forename: Beom Joon
authors.initials: BJ
authors.lastname: Kim
authors.forename: Myeung Nam
authors.initials: MN
authors.lastname: Kim
authors.forename: Kweon Soo
authors.initials: KS
authors.lastname: Kang
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Han
mesh_terms: D000328:Adult; D006177:Gynecomastia / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D015187:Lipectomy / Q000379:methods*; D008297:Male; D008327:Mammography; D009354:Neodymium; D017060:Patient Satisfaction; D014057:Tomography, X-Ray Computed; D016217:Ultrasonography, Mammary
chemical_list: D009354:Neodymium