title: Homochirality in life: two equal runners, one tripped.
abstract: Strong arguments can be found in the literature addressed to the question of the origin of homochirality in life, supporting the hypothesis that primordial life could have evolved in both homochiral forms and that early on when life was still rarely found, random events led to the survival of only one of these living mirror images. This proposal is an alternative to the generally accepted view that small enantiomeric excesses of biologically important molecules were amplified to homochirality prior to life's origin. Acceptance of the possibility of "two equal runners" leads to the importance of research investigations on routes to formation of ensembles of racemic mixtures of isotactic biologically interesting polymers, supramolecular entities and aggregates.
authors.affiliation: Herman F. Mark Polymer Research Institute, Polytechnic Institute of New York University, Brooklyn, NY 11201, USA. mgreen@duke.poly.edu
authors.forename: Mark M
authors.initials: MM
authors.lastname: Green
authors.forename: Vipul
authors.initials: V
authors.lastname: Jain
mesh_terms: D019418:Evolution, Chemical; D000069497:Origin of Life; D011108:Polymers / Q000737:chemistry; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D011108:Polymers