title: Drug interactions in dentistry.
abstract: An increasing number of our patients are on medication of various types. This increase in prescribed medicines also raises the significant issue of potential drug interactions between those drugs used in dental practice and those taken by the patient. This article addresses those interactions and, where appropriate, puts them into perspective and attempts to quantify the risk. Mechanisms of relevant drug interactions are also discussed. Certain categories of drugs are more likely to be involved in interactions and again these are highlighted. Drug interactions relevant to dentistry can for the most part be prevented. A careful drug history should be taken from each patient and updated on a regular basis.
  
  
  CONCLUSIONS
  This article highlights drug interactions that can arise in dental practice and how they can be avoided and managed.
authors.affiliation: School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4BW, UK.
authors.forename: Robin A
authors.initials: RA
authors.lastname: Seymour
mesh_terms: D000700:Analgesics / Q000009:adverse effects; D000779:Anesthetics, Local / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D004347:Drug Interactions; D006801:Humans; D008487:Medical History Taking; D053210:Pharmaceutical Preparations, Dental / Q000009:adverse effects* / Q000493:pharmacokinetics; D055553:Prescription Drugs / Q000009:adverse effects* / Q000493:pharmacokinetics; D018570:Risk Assessment
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D053210:Pharmaceutical Preparations, Dental; D055553:Prescription Drugs