title: Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.
abstract: The porcine adenovirus NADC-1 isolate, a strain of porcine adenovirus type 4, has a fibre with an atypical architecture. In addition to a classical virus attachment region, shaft and head domains, it contains an additional galectin like domain C-terminal to the head domain and connected to the head domain by a long RGD-containing loop. The galectin-like domain contains two putative carbohydrate-recognition domains. The head and galectin-like domains have been independently crystallized. Diffraction data have been obtained to 3.2 angstrom resolution from crystals of the head domain and to 1.9 angstrom resolution from galectin-like domain crystals.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Universidad de Santiago de Compostela, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Guardado-Calvo
authors.forename: Antonio L
authors.initials: AL
authors.lastname: Llamas-Saiz
authors.forename: Gavin C
authors.initials: GC
authors.lastname: Fox
authors.forename: Joel N
authors.initials: JN
authors.lastname: Glasgow
authors.forename: Mark J
authors.initials: MJ
authors.lastname: van Raaij
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003460:Crystallization; D018360:Crystallography, X-Ray; D037161:Galectins / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D011487:Protein Conformation; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013552:Swine; D015678:Viral Structural Proteins / Q000737:chemistry* / Q000235:genetics; D014961:X-Ray Diffraction
chemical_list: D037161:Galectins; D015678:Viral Structural Proteins; C099240:fiber protein NADC-1, Porcine adenovirus