title: A comparison of the periodontal status in patients with mucous membrane pemphigoid: a 5-year follow-up.
abstract: BACKGROUND
  Mucous membrane pemphigoid (MMP) is a heterogeneous group of blistering autoimmune disorders of unknown etiology. Intraoral manifestations of MMP feature the formation of vesiculobullous lesions that eventually rupture, leading to pseudomembrane-covered, irregularly-shaped ulcerations. The presence of these often painful oral lesions may hinder oral hygiene efforts resulting in increased plaque accumulation and may increase the risk of developing periodontal disease. The purpose of this study was to evaluate the changes in periodontal status in patients with MMP after a period of 5 years.
  
  
  METHODS
  Twenty patients, 10 diagnosed with MMP and 10 controls matched for age, gender, and smoking history, were chosen to participate in a study evaluating their periodontal status. Parameters evaluated included the plaque index, gingival index, bleeding index, probing depths, recession, clinical attachment level, mobility, furcation involvement, number of missing teeth, and periodontitis. Data from the same MMP and control patients were available for comparison from an identical baseline evaluation performed 5 years earlier.
  
  
  RESULTS
  Patients with MMP exhibited a statistically significant higher gingival index and amount of lingual gingival recession at both time periods compared to controls. Both groups exhibited statistically significant increases in attachment loss and facial/lingual recession, but the difference in change between groups was not statistically significant.
  
  
  CONCLUSIONS
  The results of this study suggest that patients diagnosed with MMP appear to be no more at risk than controls matched for age, gender, and smoking history in developing or having an increased progression of periodontal disease.
authors.affiliation: Department of Periodontics, Baylor College of Dentistry, The Texas A&M Health Science Center, Dallas, TX 75246, USA.
authors.forename: Austin E
authors.initials: AE
authors.lastname: Schellinck
authors.forename: Terry D
authors.initials: TD
authors.lastname: Rees
authors.forename: Jacqueline M
authors.initials: JM
authors.lastname: Plemons
authors.forename: Harvey P
authors.initials: HP
authors.lastname: Kessler
authors.forename: Francisco
authors.initials: F
authors.lastname: Rivera-Hidalgo
authors.forename: Eric S
authors.initials: ES
authors.lastname: Solomon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003774:Dental Plaque Index; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D017823:Furcation Defects / Q000145:classification; D005884:Gingival Hemorrhage / Q000145:classification; D005889:Gingival Recession / Q000145:classification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000188:drug therapy / Q000503:physiopathology*; D017622:Periodontal Attachment Loss / Q000145:classification; D010510:Periodontal Diseases / Q000145:classification*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000145:classification; D010518:Periodontitis / Q000145:classification; D012307:Risk Factors; D012907:Smoking; D016388:Tooth Loss / Q000145:classification; D014086:Tooth Mobility / Q000145:classification