Gut sensing mechanisms.
The mechanisms by which the gut senses and responds to nutrients involve the interplay of multiple complex pathways. In addition to regulating digestion and absorption, the pathways stimulated by molecules in the gut lumen mediate gastric motility, food intake, and satiety. Furthermore, protective mechanisms are activated as necessary to prevent injury, promote healing, and limit intake and absorption of potentially toxic substances. This review provides an update on the current knowledge and recent findings related to gastric sensing of nutrients, highlighting recent research and future endeavors in the field.
deFonseka
Arushi
A
West Los Angeles VA Medical Center, Building 114, Suite 217, Los Angeles, CA 90073, USA.
Kaunitz
Jonathan
J
D000818:Animals; D004063:Digestion / Q000502:physiology*; D004435:Eating / Q000502:physiology; D005502:Food; D005768:Gastrointestinal Hormones / Q000502:physiology; D005769:Gastrointestinal Motility / Q000502:physiology; D041981:Gastrointestinal Tract / Q000294:innervation / Q000502:physiology*; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology*; D012527:Satiation / Q000502:physiology; D011984:Sensory Receptor Cells / Q000502:physiology
D005768:Gastrointestinal Hormones