When children with Kawasaki disease grow up: Myocardial and vascular complications in adulthood.
Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment. In the 4 decades that have passed since the initial recognition of KD, the number of patients reaching adulthood has continued to grow. Adult cardiologists will be increasingly involved in the management of these patients. Currently, there are no established guidelines for the evaluation and treatment of adult patients who have had KD. We review here the current literature that may be helpful to clinicians who care for adults who experienced KD in childhood.
Gordon
John B
JB
San Diego Cardiac Center, San Diego, California, USA. AdultKD@gmail.com
Kahn
Andrew M
AM
Burns
Jane C
JC
D000328:Adult; D002648:Child; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000209:etiology*; D018450:Disease Progression; D006801:Humans; D015994:Incidence; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D017202:Myocardial Ischemia / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors