title: Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain.
abstract: The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.
authors.affiliation: Laboratory of Functional Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: D A
authors.initials: DA
authors.lastname: Lanshakov
authors.forename: V V
authors.initials: VV
authors.lastname: Bulygina
authors.forename: I V
authors.initials: IV
authors.lastname: Romanova
authors.forename: N N
authors.initials: NN
authors.lastname: Dygalo
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000201:enzymology*; D001933:Brain Stem / Q000201:enzymology; D053148:Caspase 3 / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic; D006624:Hippocampus / Q000201:enzymology; D007150:Immunohistochemistry; D051381:Rats; D017208:Rats, Wistar
chemical_list: D053148:Caspase 3