Recovery of methamphetamine associated cardiomyopathy predicted by late gadolinium enhanced cardiovascular magnetic resonance.
Methamphetamine is known to cause a cardiomyopathy which may be reversible with appropriate medical therapy and cessation of use. Late gadolinium enhancement cardiovascular magnetic resonance (CMR) has been shown to identify fibrosis in ischemic and non-ischemic cardiomyopathies. We present a case of severe methamphetamine-associated cardiomyopathy in which cardiac function recovered after 6 months. Evaluation by CMR using late gadolinium enhancement was notable for an absence of enhancement, suggesting an absence of irreversible myocyte injury and a good prognosis. CMR may be useful to predict recovery in toxin-associated non-ischemic cardiomyopathies.
Lopez
Javier E
JE
Department of Internal Medicine, Division of Cardiovascular Medicine, One Shields Avenue, Davis, CA 95618, USA.
Yeo
Khung
K
Caputo
Gary
G
Buonocore
Michael
M
Schaefer
Saul
S
D000328:Adult; D009202:Cardiomyopathies / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D003287:Contrast Media; D004562:Electrocardiography; D005260:Female; D005355:Fibrosis; D019786:Gadolinium DTPA; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008694:Methamphetamine / Q000009:adverse effects*; D009206:Myocardium / Q000473:pathology*; D011237:Predictive Value of Tests; D020127:Recovery of Function; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy
D000697:Central Nervous System Stimulants; D003287:Contrast Media; D008694:Methamphetamine; D019786:Gadolinium DTPA