title: Radiation therapy photon beams dose conformation according to dose distribution around intracavitary-applied brachytherapy sources.
abstract: Intracavitary application of brachytherapy sources followed by external beam radiation is essential for the local treatment of carcinoma of the cervix. Due to very high doses to the central portion of the target volume delivered by brachytherapy sources, this part of the target volume must be shielded while being irradiated by photon beams. Several shielding techniques are available, from rectangular block and standard cervix wedge to more precise, customized step wedge filters. Because the calculation of a step wedge filter's shape was usually based on effective attenuation coefficient, an approach that accounts, in a more precise way, for the scattered radiation, is suggested. The method was verified under simulated clinical conditions using film dosimetry. Measured data for various compensators were compared to the numerically determined sum of the dose distribution around brachytherapy sources and one of compensated beam. Improvements in total dose distribution are demonstrated, using our method. Agreement between calculation and measurements were within 3%. Sensitivity of the method on sources displacement during treatment has also been investigated.
authors.affiliation: Department of Radiotherapy and Oncology, University Hospital, Rijeka, Croatia. slaven.jurkovic@ri.htnet.hr
authors.forename: Slaven
authors.initials: S
authors.lastname: Jurković
authors.forename: Gordana
authors.initials: G
authors.lastname: Zauhar
authors.forename: Dario
authors.initials: D
authors.lastname: Faj
authors.forename: Deni Smilović
authors.initials: DS
authors.lastname: Radojcić
authors.forename: Manda
authors.initials: M
authors.lastname: Svabić
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods*; D003131:Combined Modality Therapy; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D017785:Photons / Q000627:therapeutic use; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000379:methods*