title: Predicting outcome of treatment for severe, treatment resistant OCD in inpatient and community settings.
abstract: Treatment of OCD is effective, even for the most chronic and severe cases. It has been difficult to identify predictors of treatment outcome, with little work aimed at predicting treatment outcome in severe OCD. We examined the ability of a range of demographic and psychopathology variables to predict treatment outcome in a cohort of 52 inpatients and a second group of 62 community outpatients with severe, treatment-refractory OCD. Despite both cohorts showing significant improvement in OCD symptoms, reliable predictors were difficult to identify, and were different in the two cohorts. In the inpatient group, marital status was a significant predictor, with those who were married or cohabiting showing better outcome that those not currently in a relationship. This relationship was not observed in the community treatment group. Initial symptom severity was also found to be a significant predictor, but only in the community treatment group, where higher initial severity was associated with greater reduction in symptoms during treatment. Further research examining a wider range of predictors may assist in identifying those factors which predict outcome in severe OCD.
authors.affiliation: South West London and St George's Mental Health NHS Trust, London, United Kingdom. m.boschen@griffith.edu.au
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Boschen
authors.forename: Lynne M
authors.initials: LM
authors.lastname: Drummond
authors.forename: Anusha
authors.initials: A
authors.lastname: Pillay
authors.forename: Katherine
authors.initials: K
authors.lastname: Morton
mesh_terms: D015928:Cognitive Behavioral Therapy / Q000379:methods*; D015331:Cohort Studies; D003153:Community Health Services; D006801:Humans; D007297:Inpatients; D017533:Marital Status; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000628:therapy*; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales