title: Dynamic jaws and dynamic couch in helical tomotherapy.
abstract: OBJECTIVE
  To investigate the next generation of helical tomotherapy delivery with dynamic jaw and dynamic couch movements.
  
  
  METHODS
  The new technique of dynamic jaw and dynamic couch movements is described, and a comparative planning study is performed. Ten nasopharyngeal cancer patients with skull base infiltration were chosen for this comparison of longitudinal dose profiles using regular tomotherapy delivery, running-start-stop treatment, and dynamic jaw and dynamic couch delivery. A multifocal simultaneous integrated boost concept was used (70.4Gy to the primary tumor and involved lymph nodes; 57.4Gy to the bilateral cervical lymphatic drainage pathways, 32 fractions). Target coverage, conformity, homogeneity, sparing of organs at risk, integral dose, and radiation delivery time were evaluated.
  
  
  RESULTS
  Mean parotid dose for all different deliveries was between 24.8 and 26.1Gy, without significant differences. The mean integral dose was lowered by 6.3% by using the dynamic technique, in comparison with a 2.5-cm-field width for regular delivery and 16.7% with 5-cm-field width for regular delivery. Dynamic jaw and couch movements reduced the calculated radiation time by 66% of the time required with regular 2.5-cm-field width delivery (199 sec vs. 595 sec, p < 0.001).
  
  
  CONCLUSIONS
  The current delivery mode of helical tomotherapy produces dose distributions with conformal avoidance of parotid glands, brain stem, and spinal cord. The new technology with dynamic jaw and couch movements improves the plan quality by reducing the dose penumbra and thereby reducing the integral dose. In addition, radiation time is reduced by 66% of the regular delivery time.
authors.affiliation: Department of Radiation Oncology, University of Heidelberg, INF 400, 69120 Heidelberg, Germany. florian.sterzing@med.uni-heidelberg.de
authors.forename: Florian
authors.initials: F
authors.lastname: Sterzing
authors.forename: Matthias
authors.initials: M
authors.lastname: Uhl
authors.forename: Henrik
authors.initials: H
authors.lastname: Hauswald
authors.forename: Kai
authors.initials: K
authors.lastname: Schubert
authors.forename: Gabriele
authors.initials: G
authors.lastname: Sroka-Perez
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Weiguo
authors.initials: W
authors.lastname: Lu
authors.forename: Rock
authors.initials: R
authors.lastname: Mackie
authors.forename: Jürgen
authors.initials: J
authors.lastname: Debus
authors.forename: Klaus
authors.initials: K
authors.lastname: Herfarth
authors.forename: Gustavo
authors.initials: G
authors.lastname: Oliveira
mesh_terms: D001933:Brain Stem / Q000528:radiation effects; D006801:Humans; D015182:Lymphatic Irradiation / Q000379:methods; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D010306:Parotid Gland / Q000528:radiation effects; D011832:Radiation Injuries / Q000517:prevention & control; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation / Q000379:methods*; D019292:Skull Base Neoplasms / Q000473:pathology / Q000532:radiotherapy; D012984:Software; D013116:Spinal Cord / Q000528:radiation effects; D013679:Technology, Radiologic / Q000295:instrumentation / Q000379:methods