title: PCBaSe Sweden: a register-based resource for prostate cancer research.
abstract: Objective. To construct a database for clinical epidemiological prostate cancer research based on linkages between the National Prostate Cancer Register (NPCR) of Sweden, a population-based, nationwide quality database, and other nationwide registries. Material and methods. By use of the individually unique Swedish Personal Identity Number, the NPCR was linked to the Swedish Cancer Registry, the Cause of Death Register, the Prescribed Drug Register, the National Patient Register and the Acute Myocardial Infarction Register, all held at the Centre for Epidemiology at the National Board of Health and Welfare, and the Register of the Total Population, the Longitudinal Integration Database for Health Insurance and Labor Market Studies and the Multi-Generation Register, held at Statistics Sweden, and to the Swedish Hernia Register. Results. Record linkages between the NPCR and the Swedish Cancer Registry, the Cause of Death Register and the Register of the Total Population generated a database, named PCBaSe Sweden, including 80 079 prostate cancer cases, diagnosed between 1 January 1996 and 31 December 2006. Record linkage between PCBaSe Sweden and the Prescribed Drug Register generated 59 721 unique matches and linkage to the Acute Myocardial Infarction Register resulted in 11 459 matches. Conclusion. PCBaSe Sweden is a newly created and unique database with over 80 000 cases of prostate cancer with comprehensive data on inpatient and outpatient care, patterns of use of prescribed drugs and socioeconomic and familial factors. Many topics in clinical prostate cancer epidemiology can be investigated. using PCBaSe Sweden.
authors.affiliation: Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden.
authors.forename: Eva
authors.initials: E
authors.lastname: Hagel
authors.forename: Hans
authors.initials: H
authors.lastname: Garmo
authors.forename: Anna
authors.initials: A
authors.lastname: Bill-Axelson
authors.forename: Ola
authors.initials: O
authors.lastname: Bratt
authors.forename: Jan-Erik
authors.initials: JE
authors.lastname: Johansson
authors.forename: Jan
authors.initials: J
authors.lastname: Adolfsson
authors.forename: Mats
authors.initials: M
authors.lastname: Lambe
authors.forename: Pär
authors.initials: P
authors.lastname: Stattin
mesh_terms: D002423:Cause of Death / Q000639:trends; D055088:Early Detection of Cancer; D006801:Humans; D015994:Incidence; D008297:Male; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D012189:Retrospective Studies; D018426:SEER Program; D013548:Sweden / Q000453:epidemiology