title: [Accomodation process: ABO-incompatible liver transplantation. Report of one case].
abstract: We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5 years, the patient remains asymptomatic and with normal liver enzymes, while she has been treated with low dose of immunosuppressive drugs. This case demonstrates an example of how the immunological process of accommodation opens the possibility of using ABO-incompatible organs as a definitive grafts.
authors.affiliation: Departamento de Medicina, Hospital San Borja-Arriarán, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
authors.forename: Lorena
authors.initials: L
authors.lastname: Castro
authors.forename: Andrés
authors.initials: A
authors.lastname: Yarur
authors.forename: Roberto
authors.initials: R
authors.lastname: Segovia
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Ponce
authors.forename: Mario
authors.initials: M
authors.lastname: Uribe
authors.forename: Mario
authors.initials: M
authors.lastname: Ferrario
authors.forename: Erwin
authors.initials: E
authors.lastname: Buckel
authors.forename: Hernán
authors.initials: H
authors.lastname: Iturriaga
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D001787:Blood Group Incompatibility / Q000276:immunology*; D005260:Female; D006085:Graft Survival / Q000276:immunology*; D006801:Humans; D017114:Liver Failure, Acute / Q000097:blood* / Q000601:surgery; D016031:Liver Transplantation / Q000276:immunology / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000017:ABO Blood-Group System