title: Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives.
abstract: The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.
authors.affiliation: Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary. fulop@pharm.u-szeged.hu
authors.forename: F
authors.initials: F
authors.lastname: Fülöp
authors.forename: I
authors.initials: I
authors.lastname: Szatmári
authors.forename: E
authors.initials: E
authors.lastname: Vámos
authors.forename: D
authors.initials: D
authors.lastname: Zádori
authors.forename: J
authors.initials: J
authors.lastname: Toldi
authors.forename: L
authors.initials: L
authors.lastname: Vécsei
mesh_terms: D003920:Diabetes Mellitus / Q000188:drug therapy; D006801:Humans; D007511:Ischemia / Q000188:drug therapy; D007736:Kynurenic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D051437:Renal Insufficiency / Q000188:drug therapy; D012559:Schizophrenia / Q000188:drug therapy
chemical_list: D007736:Kynurenic Acid