title: Pleuropulmonary blastoma in an infant.
abstract: Pleuropulmonary blastomas (PPB) are rare and highly aggressive tumors. Herein, we report an infantile case of type III PPB. A 9-mth-old boy presented to our unit with a history of cough and tachypnea for 2 days. Chest computed tomography revealed a mass in the left upper lobe, emphysema in the left upper lung, and mediastinum and heart shifted towards the right. The mass was removed completely by left upper lobectomy and histology confirmed diagnosis of type III PPB. The immature blastematous tissue was positive for vimentin while benign epithelium was positive for epithelial membrane antigen and cytokeratin. No lymph nodule metastasis was found in the 7 lymph nodules obtained from the hilum of the lung near the tumor. Currently, the patient is under close follow-up and is doing well.
authors.affiliation: Department of Pulmonology, the Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
authors.forename: Yi Cheng
authors.initials: YC
authors.lastname: Shi
authors.forename: Lan Fang
authors.initials: LF
authors.lastname: Tang
authors.forename: Zhi Min
authors.initials: ZM
authors.lastname: Chen
authors.forename: Li Zhong
authors.initials: LZ
authors.lastname: Du
mesh_terms: D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011013:Pneumonectomy; D018202:Pulmonary Blastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed