title: Which model based on fluorescence quenching is suitable to study the interaction between trans-resveratrol and BSA?
abstract: There are several models by means of quenching fluorescence of BSA to determine the binding parameters. The binding parameters obtained from different models are quite different from each other. Which model is suitable to study the interaction between trans-resveratrol and BSA? Herein, twelve models based fluorescence quenching of BSA were compared. The number of binding sites increasing with increased binding constant for similar compounds binding to BSA maybe one approach to resolve this question. For example, here eleven flavonoids were tested to illustrate that the double logarithm regression curve is suitable to study binding polyphenols to BSA.
authors.affiliation: Institute of Food Engineering, College of Life & Environment Science, Shanghai Normal University, Shanghai, PR China.
authors.forename: Xin Lin
authors.initials: XL
authors.lastname: Wei
authors.forename: Jian Bo
authors.initials: JB
authors.lastname: Xiao
authors.forename: Yuanfeng
authors.initials: Y
authors.lastname: Wang
authors.forename: Yalong
authors.initials: Y
authors.lastname: Bai
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry*; D001665:Binding Sites; D002417:Cattle; D005453:Fluorescence; D008433:Mathematics; D008956:Models, Chemical; D008958:Models, Molecular; D011485:Protein Binding; D000077185:Resveratrol; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013267:Stilbenes / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D013267:Stilbenes; D012710:Serum Albumin, Bovine; D000077185:Resveratrol