Novel nucleophilic heterocyclic carbene mediated stereoselective conjugate addition of enals to nitrostyrenes via homoenolate.
A stereoselective Michael addition of homoenolate, generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis, to beta-nitrostyrenes is reported for the first time. The products of this reaction obtained in good yields are of potential value in the synthesis of a variety of acyclic and heterocyclic compounds.
Nair
Vijay
V
Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India. Vijaynair_2001@yahoo.com
Sinu
C R
CR
Babu
Beneesh P
BP
Varghese
Vimal
V
Jose
Anu
A
Suresh
Eringathodi
E