Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain.
The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.
Lanshakov
D A
DA
Laboratory of Functional Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Bulygina
V V
VV
Romanova
I V
IV
Dygalo
N N
NN
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000201:enzymology*; D001933:Brain Stem / Q000201:enzymology; D053148:Caspase 3 / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic; D006624:Hippocampus / Q000201:enzymology; D007150:Immunohistochemistry; D051381:Rats; D017208:Rats, Wistar
D053148:Caspase 3