title: [Macular tuberculoma and optic neuritis: rare association with tuberculosis meningoencephalitis].
abstract: BACKGROUND
  Tuberculosis is an endemic disease responsible for death and morbidity in developing countries.
  
  
  METHODS
  A 50-year-old man with no medical history was admitted to the emergency department for meningism associated with fever and confusion. The ophthalmic exam showed a decline in left visual acuity, reduced to light perception, VIth nerve left oculomotor paralysis, ocular fundus demonstrating a yellow tumor located on the posterior segment, measuring 1.5-2mm, papillomatous and prominent in the vitreous cavity. Fluorescein angiography showed a peritumoral choroiditis area, miliary tubercles of the choroid, and sectorial papillomatous edema. Color retinography unmasked inflamed posterior vitreous areas. Echography demonstrated a 4- to 5-mm oval hyperechogeneous and calcified tumor along with hyperechogeneous vitreous areas. Lumbar puncture showed lymphocytic meningitis associated with hyponatremia. The CT scan and MRI demonstrated optic neuritis. The antibiotic therapy was initiated and the outcome was favorable.
  
  
  CONCLUSIONS
  This case report shows the importance of systematic ocular fundus in the presence of systemic tuberculosis and outlines the assessment of color retinography to unmask vitreous lesions. It shows the importance of radiological imaging in the semiological study of orbital and cerebral lesions.
authors.affiliation: Service d'ophtalmologie, Hôpital militaire Moulay Ismail, Meknès, Maroc. laktaoui70@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Laktaoui
authors.forename: A
authors.initials: A
authors.lastname: Naoumi
authors.forename: K
authors.initials: K
authors.lastname: Reda
authors.forename: M
authors.initials: M
authors.lastname: Kriet
authors.forename: A
authors.initials: A
authors.lastname: Elouarsani
authors.forename: A
authors.initials: A
authors.lastname: Khayati
authors.forename: A
authors.initials: A
authors.lastname: Elharradi
authors.forename: A
authors.initials: A
authors.lastname: Rouimi
authors.forename: A
authors.initials: A
authors.lastname: Douhal
authors.forename: J
authors.initials: J
authors.lastname: Mounahc
authors.forename: A
authors.initials: A
authors.lastname: Houmadi
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D002114:Calcinosis / Q000175:diagnosis / Q000209:etiology; D003221:Confusion / Q000209:etiology; D004172:Diplopia / Q000209:etiology*; D004359:Drug Therapy, Combination; D005334:Fever / Q000209:etiology; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D009902:Optic Neuritis / Q000175:diagnosis / Q000209:etiology*; D010211:Papilledema / Q000209:etiology; D011718:Pyrazinamide / Q000008:administration & dosage / Q000627:therapeutic use; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D013129:Spinal Puncture; D013307:Streptomycin / Q000008:administration & dosage / Q000627:therapeutic use; D014375:Tuberculoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid / Q000150:complications* / Q000188:drug therapy; D014463:Ultrasonography
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin