Renal scintigraphy in children with vesicoureteral reflux.
OBJECTIVE
To determine the incidence and pattern of abnormal scintigraphy findings in children with UTI and VUR.


METHODS
Data of 118 children who underwent micturating cystourethrography (MCU) and late Tc-99m dimercaptosuccinic acid (DMSA) scan were evaluated. Findings were categorized under the image appearance and relative kidney uptake (RKU) and related to the grade of VUR, sex and child's age.


RESULTS
MCU revealed VUR (78 unilateral and 40 bilateral) of grades I, II, III, IV and V in 2, 47, 35, 19 and 15 patients respectively. There were 52 children with normal and 66 with abnormal DMSA finding. Scarring rate was significantly associated with high grade VUR (p=0.0023) and male gender ( p=0.0412). Bilateral scarring was seen exclusively in children with bilateral VUR. No significant difference was found between renal scarring and child's age in the same gender group. Poor kidney function was shown in 5 patients.


CONCLUSIONS
Renal scarring highly correlated with grade of VUR. A strategy to perform MCU only on patients with abnormal DMSA finding is proposed.
Jaukovic
Ljiljana
L
Institute of Nuclear Medicine, Military Medical Academy, Belgrade, Serbia. Lilaj@EUnet.rs
Ajdinovic
Boris
B
Dopudja
Marija
M
Krstic
Zoran
Z
D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D016001:Confidence Intervals; D003558:Cystoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D011336:Probability; D011877:Radionuclide Imaging; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D016482:Urinalysis; D014552:Urinary Tract Infections / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology; D014563:Urodynamics; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology
D019783:Technetium Tc 99m Dimercaptosuccinic Acid