title: Nitrate and nitrite in biology, nutrition and therapeutics.
abstract: Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is emerging as an important mediator of blood flow regulation, cell signaling, energetics and tissue responses to hypoxia. The latest advances in our understanding of the biochemistry, physiology and therapeutics of nitrate, nitrite and NO were discussed during a recent 2-day meeting at the Nobel Forum, Karolinska Institutet in Stockholm.
authors.affiliation: Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. jon.lundberg@ki.se
authors.forename: Jon O
authors.initials: JO
authors.lastname: Lundberg
authors.forename: Mark T
authors.initials: MT
authors.lastname: Gladwin
authors.forename: Amrita
authors.initials: A
authors.lastname: Ahluwalia
authors.forename: Nigel
authors.initials: N
authors.lastname: Benjamin
authors.forename: Nathan S
authors.initials: NS
authors.lastname: Bryan
authors.forename: Anthony
authors.initials: A
authors.lastname: Butler
authors.forename: Pedro
authors.initials: P
authors.lastname: Cabrales
authors.forename: Angela
authors.initials: A
authors.lastname: Fago
authors.forename: Martin
authors.initials: M
authors.lastname: Feelisch
authors.forename: Peter C
authors.initials: PC
authors.lastname: Ford
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Freeman
authors.forename: Michael
authors.initials: M
authors.lastname: Frenneaux
authors.forename: Joel
authors.initials: J
authors.lastname: Friedman
authors.forename: Malte
authors.initials: M
authors.lastname: Kelm
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Kevil
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Kim-Shapiro
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Kozlov
authors.forename: Jack R
authors.initials: JR
authors.lastname: Lancaster
authors.forename: David J
authors.initials: DJ
authors.lastname: Lefer
authors.forename: Kenneth
authors.initials: K
authors.lastname: McColl
authors.forename: Kenneth
authors.initials: K
authors.lastname: McCurry
authors.forename: Rakesh P
authors.initials: RP
authors.lastname: Patel
authors.forename: Joel
authors.initials: J
authors.lastname: Petersson
authors.forename: Tienush
authors.initials: T
authors.lastname: Rassaf
authors.forename: Valentin P
authors.initials: VP
authors.lastname: Reutov
authors.forename: George B
authors.initials: GB
authors.lastname: Richter-Addo
authors.forename: Alan
authors.initials: A
authors.lastname: Schechter
authors.forename: Sruti
authors.initials: S
authors.lastname: Shiva
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Ernst E
authors.initials: EE
authors.lastname: van Faassen
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Webb
authors.forename: Brian S
authors.initials: BS
authors.lastname: Zuckerbraun
authors.forename: Jay L
authors.initials: JL
authors.lastname: Zweier
authors.forename: Eddie
authors.initials: E
authors.lastname: Weitzberg
mesh_terms: D000818:Animals; D004032:Diet; D004734:Energy Metabolism; D006801:Humans; D008928:Mitochondria / Q000378:metabolism; D009566:Nitrates / Q000008:administration & dosage / Q000378:metabolism* / Q000627:therapeutic use*; D009569:Nitric Oxide / Q000378:metabolism*; D009573:Nitrites / Q000008:administration & dosage / Q000378:metabolism* / Q000627:therapeutic use*; D015398:Signal Transduction
chemical_list: D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide