Toward the synthesis of benzothiazolyl fluoroaminosulfones.
Due to the importance of allylamines in organic synthesis, the synthesis of reagents as potent precursors of aminofluoroolefins is reported from functionalized benzothiazolylsulfones. The key intermediate, a fluorovinyl sulfone, was prepared and functionalized by addition of aliphatic, aromatic amines and amino acid alkyl esters through an aza-Michael addition reaction.
Calata
Charlène
C
Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507 & FR3038, ENSICAEN Université de Caen Basse-Normandie, 6 Bd du Maréchal Juin 14050 Caen Cedex, France.
Pfund
Emmanuel
E
Lequeux
Thierry
T
D000475:Alkenes / Q000737:chemistry; D000499:Allylamine / Q000031:analogs & derivatives / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D001372:Aza Compounds / Q000737:chemistry; D052160:Benzothiazoles / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D008956:Models, Chemical; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry
D000475:Alkenes; D000588:Amines; D000596:Amino Acids; D001372:Aza Compounds; D052160:Benzothiazoles; D004952:Esters; D006845:Hydrocarbons, Fluorinated; D013450:Sulfones; D000499:Allylamine