Targeting breast cancer stem cells.
Wicha
Max S
MS
University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. mwicha@umich.edu
D000444:Aldehyde Dehydrogenase / Q000097:blood; D000080924:Aldehyde Dehydrogenase 1 Family; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D000077341:Lapatinib; D009362:Neoplasm Metastasis / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D011799:Quinazolines / Q000494:pharmacology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D051880:Receptors, Notch / Q000502:physiology*; D050697:Retinal Dehydrogenase; D015398:Signal Transduction
D000444:Aldehyde Dehydrogenase; D000080924:Aldehyde Dehydrogenase 1 Family; D000970:Antineoplastic Agents; D007527:Isoenzymes; D000077341:Lapatinib; D011799:Quinazolines; D018719:Erb-b2 Receptor Tyrosine Kinases; D051880:Receptors, Notch; D050697:Retinal Dehydrogenase; C510223:ALDH1A1 protein, human