title: Alternatives to the use of animals in safety testing as required by the EU-Cosmetics Directive 2009.
abstract: Ingredients of cosmetic products are no longer allowed to be tested by animal experimentation (EU-Cosmetics Directive 76/768 EEC). For several toxicological endpoints this testing ban applies since March 11, 2009, while repeated dose toxicity tests and the test on skin sensitisation will follow on March 11, 2013. All currently available alternatives meeting the requirements of the first deadline are compiled in the following.
authors.affiliation: Bundesinstitut für Risikobewertung (BfR), ZEBET, Berlin, Germany. richard.vogel@bfr.bund.de
authors.forename: Richard
authors.initials: R
authors.lastname: Vogel
mesh_terms: D000826:Animal Testing Alternatives / Q000379:methods*; D000818:Animals; D003358:Cosmetics / Q000633:toxicity*; D017449:Dermatitis, Allergic Contact; D005062:European Union; D006801:Humans; D012871:Skin Diseases / Q000139:chemically induced; D018675:Toxicity Tests / Q000941:ethics / Q000379:methods*
chemical_list: D003358:Cosmetics