Giant cell angiitis of the central nervous system with atypical presentation.
Giant cell angiitis of the CNS is an uncommon form of vasculitis. Neurological manifestations, both of the peripheral and CNS, are common. The most frequent manifestations are visual loss and stroke. Hemorrhagic onset is uncommon. Most cases have a fatal outcome and a tissue diagnosis is rarely established in life. We describe an unusual case of giant cell angiitis beginning as a hemorrhagic tumoral-like lesion. The results of the histological and ultrastructural analysis have also been reported. Our case illustrates that giant cell angiitis should be considered as a cause of intracerebral hemorrhage, particularly when associated with a relapsing and remitting disease of the CNS.
Ciappetta
Pasqualino
P
Department of Neurological and Psychiatric Sciences, University of Bari Medical Schoo, Bari, Italy.
D'Urso
Pietro Ivo
PI
Colamaria
Antonio
A
Lauta
Enrico
E
Cimmino
Antonia
A
D'Urso
Oscar Fernando
OF
Rossi
Roberta
R
Resta
Leonardo
L
Ingravallo
Giuseppe
G
D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000150:complications / Q000473:pathology; D015726:Giant Cells / Q000648:ultrastructure*; D006406:Hematoma / Q000150:complications / Q000473:pathology; D006521:Hepatitis, Chronic / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D046529:Microscopy, Electron, Transmission; D013274:Stomach Neoplasms / Q000150:complications; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000150:complications / Q000473:pathology*