title: Structural investigation of biologically active phenolic compounds isolated from European tree species.
abstract: X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the Dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.
authors.affiliation: Institute of Technical Biochemistry, Technical University of Łódź, ul. Stefanowskiego 4/10, 90-924 Łódź, Poland. izared@p.lodz.pl
authors.forename: Izabela
authors.initials: I
authors.lastname: Redzynia
authors.forename: Natasza E
authors.initials: NE
authors.lastname: Ziółkowska
authors.forename: Wiesław R
authors.initials: WR
authors.lastname: Majzner
authors.forename: Stefan
authors.initials: S
authors.lastname: Willför
authors.forename: Rainer
authors.initials: R
authors.lastname: Sjöholm
authors.forename: Patrik
authors.initials: P
authors.lastname: Eklund
authors.forename: Grzegorz D
authors.initials: GD
authors.lastname: Bujacz
mesh_terms: D028202:Abies / Q000737:chemistry*; D005060:Europe; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D005663:Furans / Q000737:chemistry* / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D059808:Polyphenols; D032107:Populus / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D005419:Flavonoids; D005663:Furans; D017705:Lignans; D010636:Phenols; D059808:Polyphenols; C060282:lariciresinol; C080220:aromadedrin