The UCSC Genome Browser database: update 2010.
The University of California, Santa Cruz (UCSC) Genome Browser website (http://genome.ucsc.edu/) provides a large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users' own annotation data. As of September 2009, genomic sequence and a basic set of annotation 'tracks' are provided for 47 organisms, including 14 mammals, 10 non-mammal vertebrates, 3 invertebrate deuterostomes, 13 insects, 6 worms and a yeast. New data highlights this year include an updated human genome browser, a 44-species multiple sequence alignment track, improved variation and phenotype tracks and 16 new genome-wide ENCODE tracks. New features include drag-and-zoom navigation, a Wiki track for user-added annotations, new custom track formats for large datasets (bigBed and bigWig), a new multiple alignment output tool, links to variation and protein structure tools, in silico PCR utility enhancements, and improved track configuration tools.
Rhead
Brooke
B
Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA. rhead@soe.ucsc.edu
Karolchik
Donna
D
Kuhn
Robert M
RM
Hinrichs
Angie S
AS
Zweig
Ann S
AS
Fujita
Pauline A
PA
Diekhans
Mark
M
Smith
Kayla E
KE
Rosenbloom
Kate R
KR
Raney
Brian J
BJ
Pohl
Andy
A
Pheasant
Michael
M
Meyer
Laurence R
LR
Learned
Katrina
K
Hsu
Fan
F
Hillman-Jackson
Jennifer
J
Harte
Rachel A
RA
Giardine
Belinda
B
Dreszer
Timothy R
TR
Clawson
Hiram
H
Barber
Galt P
GP
Haussler
David
D
Kent
W James
WJ
D000818:Animals; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D014644:Genetic Variation; D016678:Genome; D016681:Genome, Fungal; D023281:Genomics; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D007448:Invertebrates; D008958:Models, Molecular; D010641:Phenotype; D012984:Software