title: 4-Fluoro-2,4-methanoproline.
abstract: The first fluorinated analogue of the naturally occurring 2,4-methanoproline, 4-fluoro-2,4-methanoproline, has been synthesized in five steps from commercially available methyl 2-fluoroacrylate through a photochemical cyclization as a key step in generating a 2-azabicyclo[2.1.1]hexane skeleton.
authors.affiliation: Department of Chemistry, Kyiv National Taras Shevchenko University, Vul. Volodymyrska 64, 01033 Kyiv, Ukraine.
authors.forename: Anton N
authors.initials: AN
authors.lastname: Tkachenko
authors.forename: Dmytro S
authors.initials: DS
authors.lastname: Radchenko
authors.forename: Pavel K
authors.initials: PK
authors.lastname: Mykhailiuk
authors.forename: Oleksandr O
authors.initials: OO
authors.lastname: Grygorenko
authors.forename: Igor V
authors.initials: IV
authors.lastname: Komarov
mesh_terms: D053961:Azabicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011392:Proline / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D053961:Azabicyclo Compounds; D006845:Hydrocarbons, Fluorinated; D011392:Proline