Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles.
N-Sulfonyl 1,2,3-triazoles readily form rhodium(II) azavinyl carbenes, which react with olefins to produce cyclopropanes with excellent diastereo- and enantioselectivity and in high yield.
Chuprakov
Stepan
S
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Kwok
Sen Wai
SW
Zhang
Li
L
Lercher
Lukas
L
Fokin
Valery V
VV
D000475:Alkenes / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013450:Sulfones / Q000737:chemistry; D014230:Triazoles / Q000737:chemistry*
D000475:Alkenes; D001372:Aza Compounds; D003521:Cyclopropanes; D013450:Sulfones; D014230:Triazoles; D012238:Rhodium