Pulmonary hypertension in pregnancy: two cases and review of the literature.
Pulmonary arterial hypertension (PAH) in pregnancy carries a mortality of 30-56%. There are few published data to guide clinicians in its management. Two pregnant women with severe PAH have been treated at Royal Perth Hospital with a successful result in both. Their presentation and management are described. We review the physiological changes in pregnancy, pathophysiology in PAH, and review the literature describing treatment of PAH in pregnancy.
Higton
A M
AM
Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth Western Australia, Australia.
Whale
C
C
Musk
M
M
Gabbay
E
E
D000328:Adult; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D055815:Young Adult