title: Familial furunculosis associated with community-acquired leukocidin-positive methicillin-susceptible Staphylococcus aureus ST152.
abstract: Panton-Valentine leukocidin (PVL) is associated with staphylococcal skin and pulmonary infections. Community dissemination of PVL-producing Staphylococcus aureus strains constitutes a public health concern. Family transmission and spread of community-acquired leukocidin-positive methicillin-susceptible S. aureus ST152 isolates associated with severe clinical symptoms are herein described. Remarkably, ST152 isolates usually are methicillin resistant.
authors.affiliation: Unidad de Investigación, Hospital Universitario NS Candelaria, Ctra. del Rosario 100, 38010 Santa Cruz de Tenerife, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Pérez-Roth
authors.forename: J
authors.initials: J
authors.lastname: Alcoba-Flórez
authors.forename: C
authors.initials: C
authors.lastname: López-Aguilar
authors.forename: I
authors.initials: I
authors.lastname: Gutiérrez-González
authors.forename: B
authors.initials: B
authors.lastname: Rivero-Pérez
authors.forename: S
authors.initials: S
authors.lastname: Méndez-Alvarez
mesh_terms: D000293:Adolescent; D000328:Adult; D001426:Bacterial Proteins / Q000096:biosynthesis; D015373:Bacterial Typing Techniques; D002648:Child; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D016172:DNA Fingerprinting; D005192:Family Health; D005667:Furunculosis / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D005838:Genotype; D006801:Humans; D007956:Leukocidins / Q000096:biosynthesis; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012150:Polymorphism, Restriction Fragment Length; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D037521:Virulence Factors / Q000096:biosynthesis
chemical_list: D001426:Bacterial Proteins; D007956:Leukocidins; D037521:Virulence Factors