Pouchitis and pouch dysfunction.
Restorative proctocolectomy with ileal pouch-anal anastomosis has become the surgical treatment of choice for most patients with ulcerative colitis who require surgery. Although the surgical procedure offers a cure in some patients, postoperative inflammatory and noninflammatory complications are common. Pouchitis is the most common long-term complication of the procedure. Pouchitis represents a spectrum of disease processes with heterogeneous risk factors, clinical phenotypes, natural history, and prognosis. Accurate diagnosis and classification are important for proper treatment and prognosis.
Wu
Hao
H
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China.
Shen
Bo
B
D003093:Colitis, Ulcerative / Q000601:surgery*; D006801:Humans; D015994:Incidence; D019449:Pouchitis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D015995:Prevalence; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*; D012307:Risk Factors