title: Loxoscelism and negative pressure wound therapy (vacuum-assisted closure): a clinical case series.
abstract: Brown recluse spider (Loxosceles sp) bites continue to be a significant challenge to manage clinically. Sequelae from these lesions range from chronic necrotic ulcers that persist for months to an acute life-threatening course of sepsis. Negative pressure wound therapy using vacuum-assisted closure (VAC) has been described for use in both acute and chronic wounds. We present a novel application for the use of this therapy in a retrospective review of eight clinical cases treated with the VAC.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1075, USA.
authors.forename: S Lindsey
authors.initials: SL
authors.lastname: Wong
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Defranzo
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Morykwas
authors.forename: Louis C
authors.initials: LC
authors.lastname: Argenta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D012883:Skin Ulcer / Q000209:etiology / Q000628:therapy*; D001098:Spider Bites / Q000150:complications* / Q000628:therapy; D014945:Wound Healing; D055815:Young Adult