New factor characterizing the in-mouth release of odorants (volatile thiols): compositional changes in odorants exhaled from the human nose during drinking.
The aim of this research was to investigate the relationship between the odorants in the model drink and the odorants reaching the olfactory epithelium using the Retronasal Flavor Impression Screening System (R-FISS). By application of the R-FISS to the odorants in the model drink, it was found that a methylthio ether [1-methoxy-3-methyl-3-(methylthio)butane] was detected with the original volatile thiol (4-methoxy-2-methyl-2-mercaptobutane) in the air exhaled through the nostrils via the nasal cavity after the model drink (including the original thiol) had been swallowed. In addition, this phenomenon was also observed in other volatile thiols (furfuryl mercaptan, ethyl 2-mercaptopropionate, 2-methyl-1-mercaptobutane, and 4-mercapto-4-methyl-2-pentanone). These compositional changes in thiols that were observed in the air exhaled through the nostrils could be affected by the chemical structure of each tested thiol and individual differences. These results pointed to a possibility that the odorants reaching the olfactory receptor via the throat during consumption of foods could not always retain their original chemical structures and compositions in foodstuffs. Therefore, the characteristic odor of volatile thiols might be perceived due to the stimuli of multiple compounds. To understand in detail flavor perception during the consumption of foods, not only the compositions or amounts of odorants in foodstuffs but also the compositional changes in odorants induced by biological reactions (reduction or methylation) need to be taken into consideration.
Itobe
Takafumi
T
Ogawa & Company, Ltd., 15-7 Chidori Urayasushi, Chiba 279-0032, Japan. itobe.takafumi@ogawa.net
Kumazawa
Kenji
K
Nishimura
Osamu
O
D045853:Exhalation; D006801:Humans; D009055:Mouth / Q000737:chemistry* / Q000502:physiology; D009666:Nose / Q000737:chemistry* / Q000502:physiology; D009812:Odorants / Q000032:analysis*; D055696:Olfactory Perception; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D014835:Volatilization
D013438:Sulfhydryl Compounds