title: Continuous estrogen decreases neurokinin B expression in the rat arcuate nucleus.
abstract: Immunohistochemical and in situ hybridization histochemical techniques were used to identify neurokinin B (NKB, also known as neuromedin K or neurokinin beta) as the predominant tachykinin present in cells of the arcuate nucleus of the rat. Little is known about the function of NKB; however, its localization in the arcuate nucleus and the observation that Silastic implants of estrogen for 2 weeks decreases the numbers of labeled cells sutgest a role in gonadal steroid-dependent mechanisms that regulate the anterior pituitary.
authors.affiliation: Department of Anatomy and Cell Biology and the Laboratory of Neuroendocrinology, UCLA School of Medicine, Los Angeles, California 90024, USA; Department of Medicine and Center for Ulcer Research and Education, Wadsworth Veterans Administration, UCLA School of Medicine, Los Angeles, California 90024, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Akesson
authors.forename: C
authors.initials: C
authors.lastname: Sternini
authors.forename: P E
authors.initials: PE
authors.lastname: Micevych