If at first you don't succeed: a difficult case of Linear IgA.
We present a patient with Linear IgA who was both difficult to diagnose and treat. Numerous biopsies were needed before a positive result could be returned. Trials of multiple systemic agents failed. Eventually, a second trial of dapsone was successful and well-tolerated. The case exemplifies the determination and perseverance that is often required by both patient and physician in pursuit of symptom relief.
Krejci-Manwaring
Jennifer
J
West
Daniel A
DA
Tonkovic-Capin
Viseslav
V
D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D003622:Dapsone / Q000009:adverse effects / Q000627:therapeutic use*; D003951:Diagnostic Errors; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006261:Headache / Q000139:chemically induced; D006562:Herpes Zoster / Q000175:diagnosis; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007070:Immunoglobulin A / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D007169:Impetigo / Q000175:diagnosis; D019964:Mood Disorders / Q000139:chemically induced; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D012532:Scabies / Q000175:diagnosis; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology
D007070:Immunoglobulin A; D007166:Immunosuppressive Agents; D003622:Dapsone; D011241:Prednisone; D006854:Hydrocortisone