title: Spectral domain optical coherence tomography in diabetic macular edema.
abstract: OBJECTIVE
  To compare the images obtained from Stratus time domain optical coherence tomography (OCT) (Carl Zeiss Meditec, Inc., Dublin, CA) and Cirrus spectral domain OCT (Cirrus HD-OCT 4000 model; Carl Zeiss Meditec, Inc.) in patients with diabetic macular edema.
  
  
  METHODS
  This observational retrospective case series was created using the charts of 20 patients with diabetes mellitus diagnosed as having diabetic macular edema. All patients had both Stratus and Cirrus OCT imaging completed on the same day. Qualitative comparisons were performed by two experienced clinicians in an unmasked fashion. Central macular thickness and central foveal thickness were recorded.
  
  
  RESULTS
  Thirty-six eyes of 20 patients with diabetes mellitus were analyzed. Features such as cystoid spaces, highly reflective lesions, vitreoretinal interface, serous retinal detachment, and photoreceptors inner/outer segments were more often detected with the Cirrus OCT than with the Stratus OCT. Considering the same reference lines for evaluation of central macular thickness and central foveal thickness, the same values were obtained with both devices.
  
  
  CONCLUSIONS
  Cirrus OCT enables easier observation of normal structures and retinal abnormalities than the Status OCT. Furthermore, lesions may be accurately identified and quantified by the Cirrus OCT.
authors.affiliation: Department of Ophthalmology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Université Paris 7, Paris, France.
authors.forename: Jean-Antoine C
authors.initials: JA
authors.lastname: Pournaras
authors.forename: Ali
authors.initials: A
authors.lastname: Erginay
authors.forename: Zineb
authors.initials: Z
authors.lastname: Lazrak
authors.forename: Alain
authors.initials: A
authors.lastname: Gaudric
authors.forename: Pascale
authors.initials: P
authors.lastname: Massin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult