title: Evaluation and management of psoriasis: an internist's guide.
abstract: Psoriasis is a debilitating chronic skin condition that afflicts millions of patients worldwide. Patients experiencing psoriasis report a magnitude of impaired quality of life that is often similar to that of patients who have heart failure and cancer. Many patients who have psoriasis are even themselves at risk for developing heart disease, metabolic syndrome, certain cancers, and psychiatric illness. Therefore, primary care physicians must appreciate the current psoriatic disease model and share a basic understanding of psoriasis management. This article reviews the epidemiology, clinical features, pathogenesis, comorbidities, and treatment of psoriasis, with special emphasis placed on the new class of medications, biologics, which are revolutionizing the management of the disease.
authors.affiliation: Department of Dermatology, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Boston, MA 02111, USA.
authors.forename: Danielle
authors.initials: D
authors.lastname: Levine
authors.forename: Alice
authors.initials: A
authors.lastname: Gottlieb
mesh_terms: D015897:Comorbidity; D020022:Genetic Predisposition to Disease; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D010789:Phototherapy; D011565:Psoriasis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents