Synthesis of carbamates from diethoxycarbonyl hydrazine derivatives by E1cB eliminative cleavage of the N-N'-bond rather than reduction.
Treatment of diethoxycarbonyl hydrazine derivatives with methyl bromoacetate/Cs(2)CO(3)/MeCN at 50 degrees C followed by heating to 80 degrees C resulted in N-N' bond cleavage to the corresponding carbamates.
Magnus
Philip
P
Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-1167, USA. p.magnus@mail.utexas.edu
Garizi
Negar
N
Seibert
Kimberly A
KA
Ornholt
Alexandra
A