title: Human rotavirus genotypes in hospitalized children, South Korea, April 2005 to March 2007.
abstract: Availability of new rotavirus vaccines highlights the need to maintain and enhance rotavirus strain surveillance. We collected stool samples from children with gastroenteritis admitted to eight hospitals in South Korea from April 2005 to March 2007. Of the 6057 samples collected, 1337 (22%) were positive for rotavirus by one of several antigen detection assays. G and P genotypes were identified for 1299 (97%) of rotavirus-positive specimens. G1P[8] (36%) was the most prevalent strain, followed by G3P[8] (16%), G4P[6] (8.9%) and G1P[6] (8.2%). G1P[8] was also the most prevalent strain in each hospital. Seasonal peaks of rotavirus infection were noted from November 2005 to April 2006 and January to March 2007. This large-scale surveillance study provides important insights into rotavirus genotype distribution and pattern changes in South Korea.
authors.affiliation: Department of Pediatrics, College of Medicine, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, South Korea.
authors.forename: S Y
authors.initials: SY
authors.lastname: Lee
authors.forename: S K
authors.initials: SK
authors.lastname: Hong
authors.forename: S G
authors.initials: SG
authors.lastname: Lee
authors.forename: C I
authors.initials: CI
authors.lastname: Suh
authors.forename: S W
authors.initials: SW
authors.lastname: Park
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: D S
authors.initials: DS
authors.lastname: Kim
authors.forename: H M
authors.initials: HM
authors.lastname: Kim
authors.forename: Y T
authors.initials: YT
authors.lastname: Jang
authors.forename: S H
authors.initials: SH
authors.lastname: Ma
authors.forename: S Y
authors.initials: SY
authors.lastname: Kim
authors.forename: Y S
authors.initials: YS
authors.lastname: Sohn
authors.forename: J H
authors.initials: JH
authors.lastname: Kang
authors.forename: S Y
authors.initials: SY
authors.lastname: Paik
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D002673:Child, Hospitalized / Q000706:statistics & numerical data; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D011159:Population Surveillance; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012401:Rotavirus / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology*
chemical_list: D000956:Antigens, Viral