title: Nodular glomerulosclerosis in patients' without history of diabetes mellitus: a case report.
abstract: BACKGROUND
  Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus.
  
  
  METHODS
  We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes.
  
  
  CONCLUSIONS
  Renal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject.
authors.affiliation: Department of Internal Medicine A and Laboratory of Kidney Pathology 02, Charles Nicolle Hospital Boulevard 9 Avril. 1006 Tunis Tunisia. imedhelal@voila.fr
authors.forename: Imed
authors.initials: I
authors.lastname: Helal
authors.forename: Rym
authors.initials: R
authors.lastname: Goucha
authors.forename: Cyrine
authors.initials: C
authors.lastname: Karoui
authors.forename: Ezzedine
authors.initials: E
authors.lastname: Abderrahim
authors.forename: Fethi Ben
authors.initials: FB
authors.lastname: Hamida
authors.forename: Fethi
authors.initials: F
authors.lastname: Elyounsi
authors.forename: Hedi Ben
authors.initials: HB
authors.lastname: Maiz
authors.forename: Taieb Ben
authors.initials: TB
authors.lastname: Abdallah
authors.forename: Adel
authors.initials: A
authors.lastname: Kheder