Delayed inflammatory reaction to bio-alcamid polyacrylamide gel used for soft-tissue augmentation.
BACKGROUND
Given the recent boom of the cosmetic industry, there is a wealth of new products available to patients and physicians, including soft-tissue fillers. Bio-Alcamid polyacrylamide gel (Polymekon, Milan, Italy) is a filler that has potential to cause adverse reactions.


METHODS
Two patients who had previously been treated with Bio-Alcamid outside of the United States presented with different manifestations of inflammatory responses to the product. These reactions were challenging to treat.


CONCLUSIONS
Despite claims of safety, Bio-Alcamid and possibly other soft-tissue fillers available worldwide have the potential to cause adverse reactions. Physicians should be aware of the various presentations and treatment options for these reactions.
Chrastil-LaTowsky
Brenda
B
SkinCare Physicians, 1244 Boylston St, Ste 103, Chestnut Hill, MA 02467, USA. blatowsky@yahoo.com
Wesley
Naissan O
NO
MacGregor
Jennifer L
JL
Kaminer
Michael S
MS
Arndt
Kenneth A
KA
D000180:Acrylic Resins / Q000009:adverse effects* / Q000627:therapeutic use; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003357:Cosmetic Techniques / Q000009:adverse effects*; D003872:Dermatitis / Q000209:etiology* / Q000628:therapy; D004322:Drainage / Q000379:methods; D004487:Edema / Q000139:chemically induced* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007279:Injections, Subcutaneous; D018570:Risk Assessment; D012720:Severity of Illness Index; D015595:Skin Aging / Q000187:drug effects; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States
D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; C470344:Bio-Alcamid; C016680:polyacrylamide gels