Molecular characterization of adenovirus circulating in Central and South America during the 2006-2008 period.
BACKGROUND
Human Adenoviruses are recognized pathogens, causing a broad spectrum of diseases. Serotype identification is critical for epidemiological surveillance, detection of new strains and understanding of HAdvs pathogenesis. Little data is available about HAdvs subtypes in Latin America.


METHODS
In this study, we have molecularly characterized 213 adenoviruses collected from ILI presenting patients, during 2006-08, in Central and South America.


RESULTS
Our results indicate that 161(76%) adenoviruses belong to subgroup C, 45 (21%) to subgroup B and 7 (3%) to subtype E4.
García
Josefina
J
US Naval Medical Research Center Detachment, Lima, Peru. josefina.garcia@med.navy.mil
Sovero
Merly
M
Laguna-Torres
Victor Alberto
VA
Gomez
Jorge
J
Chicaiza
Wilson
W
Barrantes
Melvin
M
Sanchez
Felix
F
Jimenez
Mirna
M
Comach
Guillermo
G
de Rivera
Ivette L
IL
Agudo
Roberto
R
Arango
Ana E
AE
Barboza
Alma
A
Aguayo
Nicolas
N
Kochel
Tadeusz J
TJ
D000258:Adenovirus Infections, Human / Q000453:epidemiology* / Q000821:virology*; D000260:Adenoviruses, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D036022:Capsid Proteins / Q000235:genetics; D002489:Central America / Q000453:epidemiology; D016000:Cluster Analysis; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D013020:South America / Q000453:epidemiology
D036022:Capsid Proteins; D004279:DNA, Viral; C018315:hexon capsid protein, Adenovirus