title: [Chronic rhinosinusitis in morbus widal: clinical aspects and therapeutic options].
abstract: Chronic rhinosinusitis is often associated with bronchial asthma. If it's joined by intolerance to analgetics we call it Morbus Widal or Samters Trias. Especially chronic rhinosinusitis is often difficult to treat in these patients. Mostly the patients suffer a lot from nasal symptoms. This article presents the clinical aspects with a special focus on the therapy with acetylsalicylacid (ASA). The substance is used to induce a tolerance against ASA or other NSAID (desensitization or "adaptive desactivation") with the purpose to improve the symptoms in the upper airways sustainable. As addition we present a retrospective study generated out of data of our own patients.
authors.affiliation: Hochgebirgsklinik Davos, Davos Wolfgang. harald.jung@hgk.ch
authors.forename: H
authors.initials: H
authors.lastname: Jung
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D001249:Asthma / Q000139:chemically induced* / Q000188:drug therapy; D002908:Chronic Disease; D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D012008:Recurrence; D012220:Rhinitis / Q000175:diagnosis / Q000628:therapy; D012852:Sinusitis / Q000175:diagnosis / Q000628:therapy; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D020024:Leukotriene Antagonists; D001241:Aspirin