Oral fluid tests for screening of human immunodeficiency virus-exposed infants.
In high human immunodeficiency virus (HIV) prevalence settings, routine screening of infants attending immunization visits could improve identification of HIV-exposed infants to receive an early diagnosis and appropriate interventions. This first assessment of 2 rapid oral fluid HIV tests in early infancy demonstrates a sensitivity of <90% for detection of HIV-exposure resulting in failure to detect at least 1 in 10 HIV-infected infants.
Sherman
Gayle G
GG
Department of Molecular Medicine and Haematology, Medical School, University of the Witwatersrand, Parktown, Johannesburg, South Africa. gayle.sherman@nhls.ac.za
Lilian
Rivka R
RR
Coovadia
Ashraf H
AH
D005260:Female; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies / Q000032:analysis*; D015658:HIV Infections / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008403:Mass Screening / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D012463:Saliva / Q000276:immunology*; D012680:Sensitivity and Specificity
D015483:HIV Antibodies; D011933:Reagent Kits, Diagnostic