title: Continuous glucose monitor shows potential for early hypoglycemia detection in hospitalized patients.
abstract: OBJECTIVE
  This study shows the potential of continuous glucose monitoring (CGM) for the detection of hypoglycemia in hospitalized patients.
  
  
  METHODS
  A Medtronic Diabetes (Northridge, CA) CGMS iPro continuous glucose recorder was inserted into the subcutaneous tissue of a hospitalized orthopedic surgery patient with type 1 diabetes the day after a moderate hypoglycemia event. The interstitial fluid glucose concentration was recorded every 5 min. Both the patient and the hospital staff were blinded to the CGM data. Bedside capillary blood glucose measurements were performed per hospital protocol.
  
  
  RESULTS
  The CGM recorded a repeat severe episode of hypoglycemia the next day. The hospital-defined threshold for hypoglycemia (70 mg/dL) was crossed 4.5 h prior to the patient being found unconscious by the nursing staff.
  
  
  CONCLUSIONS
  Data from the CGMS iPro Recorder illustrate the potential benefit of using a real-time CGM in the hospital to detect hypoglycemia in a more timely fashion compared to infrequent point-of-care glucose meter measurements.
authors.affiliation: Department of Medicine, The Artificial Pancreas Center, Philadelphia, Pennsylvania, USA.
authors.forename: Margaret T
authors.initials: MT
authors.lastname: Ryan
authors.forename: Vincent W
authors.initials: VW
authors.lastname: Savarese
authors.forename: Brian
authors.initials: B
authors.lastname: Hipszer
authors.forename: Ismar
authors.initials: I
authors.lastname: Dizdarevic
authors.forename: Mark
authors.initials: M
authors.lastname: Joseph
authors.forename: Nathan
authors.initials: N
authors.lastname: Shively
authors.forename: Jeffrey I
authors.initials: JI
authors.lastname: Joseph
mesh_terms: D000328:Adult; D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis*; D015918:Infusion Pumps, Implantable; D007332:Insulin Infusion Systems; D018670:Monitoring, Ambulatory / Q000379:methods; D010353:Patient Education as Topic; D010361:Patients
chemical_list: D001786:Blood Glucose