Silver- and gold-catalyzed intramolecular rearrangement of propargylic alcohols tethered with methylenecyclopropanes: stereoselective synthesis of allenylcyclobutanols and 1-vinyl-3-oxabicyclo[3.2.1]octan-8-one derivatives.
Ag(I)-catalyzed intramolecular reaction of monoarylmethylenecyclopropanes (MCPs) tethered with 1,1,3-triarylprop-2-yn-1-ols provides diastereoselective access to polysubstituted allenylcyclobutanols and the obtained allenylcyclobutanols catalyzed by Au(I) furnish a wide range of bridged bicyclic compounds with a vinyl-substituted quaternary stereogenic center stereoselectively.
Yao
Liang-Feng
LF
School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Lu, Shanghai 200237, China.
Wei
Yin
Y
Shi
Min
M