title: [Quantification of myocardial scintigraphy in patients with low probability of coronary artery disease. Normal values of thallium-201 gated SPECT].
abstract: BACKGROUND
  This study has aimed to establish quantitative normality parameters in the thallium-201 GATED SPECT and to assess the changes related to age, gender, risk factors and stress testing.
  
  
  METHODS
  A total of 427 patients with low pre-test likelihood of coronary artery disease were selected (45.5% men). The examinations were performed, by obtaining 32 25-second images on a 180% arc. The isotope used was thallium-201 and the SU SEGAMI software was using for the examination procedure.
  
  
  RESULTS
  Myocardial tracer uptake in each one of the vascular territories was: left descending artery 77%+/-4; circumflex artery 76%+/-5 and right coronary artery 70%+/-4 (P=.000). Uptake in the right coronary artery territory was lower in men (68.7% vs 70.5% in women, P=.000) and in the left descending artery territory in the obese. There were no gender-related differences in the post-stress ejection fraction for both genders (65.7% in men vs 66.8% in women). However, ventricular volumes were higher in men (end-diastolic volume 80ml+/-27 vs 61ml+/-22; P=0.000 and end-systolic volume 27.2ml+/-25 vs 19ml+/-8; P=0.000). There is an inverse relationship between age and end-diastolic volume. Smokers have higher end-diastolic volumes than non-smokers.
  
  
  CONCLUSIONS
  Quantification of T1201 uptake in patients having low pre-test probability of coronary artery disease and normal thallium GATED-SPECT in the RCA territory is lower in men. The ventricular function study shows that there are no differences in post-stress EF based on gender but that the end-diastolic and end-systolic volumes are higher in men.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Carlos III, Madrid, España. mgomez.hciii@salud.madrid.org
authors.forename: M
authors.initials: M
authors.lastname: Del Val Gómez
authors.forename: F G
authors.initials: FG
authors.lastname: Gallardo
authors.forename: R
authors.initials: R
authors.lastname: Peraira
authors.forename: A
authors.initials: A
authors.lastname: García
authors.forename: I
authors.initials: I
authors.lastname: Terol
mesh_terms: D000367:Age Factors; D003327:Coronary Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000503:physiopathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006973:Hypertension / Q000150:complications; D008297:Male; D055414:Myocardial Perfusion Imaging; D009765:Obesity / Q000150:complications; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012306:Risk; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking; D013318:Stroke Volume; D013794:Thallium Radioisotopes / Q000493:pharmacokinetics; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes