title: Personalized management of patients with inoperable alveolar echinococcosis undergoing treatment with albendazole: usefulness of positron-emission-tomography combined with serological and computed tomography follow-up.
abstract: The present study aimed to identify a sub-group of inoperable alveolar echinococcosis (AE) patients undergoing long-term treatment with benzimidazole (BZM) who presented with an evolution suggestive of a parasitocidal effect. An evolution compatible with parasite death was observed in five patients.
authors.affiliation: WHO Collaborating Center for Prevention and Treatment of Human Echinococcosis, University Hospital, Besançon, France.
authors.forename: J
authors.initials: J
authors.lastname: Crouzet
authors.forename: F
authors.initials: F
authors.lastname: Grenouillet
authors.forename: E
authors.initials: E
authors.lastname: Delabrousse
authors.forename: O
authors.initials: O
authors.lastname: Blagosklonov
authors.forename: T
authors.initials: T
authors.lastname: Thevenot
authors.forename: V
authors.initials: V
authors.lastname: Di Martino
authors.forename: R
authors.initials: R
authors.lastname: Piarroux
authors.forename: G A
authors.initials: GA
authors.lastname: Mantion
authors.forename: S
authors.initials: S
authors.lastname: Bresson-Hadni
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000909:Antibodies, Helminth / Q000097:blood; D016903:Drug Monitoring / Q000379:methods*; D004443:Echinococcosis; D004444:Echinococcosis, Hepatic / Q000175:diagnosis / Q000188:drug therapy; D004446:Echinococcus / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods; D011860:Radiography, Abdominal / Q000379:methods; D012698:Serologic Tests; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000871:Anthelmintics; D000909:Antibodies, Helminth; D015766:Albendazole