Antimalarial drug development: past to present scenario.
Malaria is a global health problem that needs attention of drug discovery scientists to investigate novel compounds with high drug efficacy, safety and low cost to counter the malaria parasites that are resistant to existing drug molecules. This is an overview of past to present status of antimalarial drugs including newly researched candidates and also the alternative approaches for the complete control of malaria.
Dhanawat
Meenakshi
M
Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005, U.P., India. mdanawat.rs.phe@itbhu.ac.in
Das
Nirupam
N
Nagarwal
Ramesh C
RC
Shrivastava
S K
SK
D000634:Aminoquinolines / Q000737:chemistry / Q000494:pharmacology; D000962:Antimalarials / Q000737:chemistry* / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology; D056831:Coordination Complexes / Q000737:chemistry / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005493:Folic Acid Antagonists / Q000737:chemistry / Q000494:pharmacology; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008288:Malaria / Q000188:drug therapy; D017780:Malaria Vaccines / Q000494:pharmacology; D010545:Peroxides / Q000737:chemistry / Q000494:pharmacology; D045568:Tetraoxanes / Q000737:chemistry / Q000494:pharmacology
C503429:1,2,4-trioxane; D000634:Aminoquinolines; D000962:Antimalarials; D001688:Biological Products; D056831:Coordination Complexes; D005493:Folic Acid Antagonists; D006571:Heterocyclic Compounds; D017780:Malaria Vaccines; D010545:Peroxides; D045568:Tetraoxanes