Voltage-sensitive dye imaging: Technique review and models.
In this review, we present the voltage-sensitive dye imaging (VSDI) method. The possibility offered for in vivo (and in vitro) brain imaging is unprecedented in terms of spatial and temporal resolution. However, the unresolved multi-component origin of the optical signal encourages us to perform a detailed analysis of the method limitation and the existing models. We propose a biophysical model at a mesoscopic scale in order to understand and interpret this signal.
Chemla
S
S
NeuroMathComp Team, INRIA Sophia-Antipolis, France. sandrine.chemla@sophia.inria.fr
Chavane
F
F
D000818:Animals; D001703:Biophysics; D001921:Brain / Q000166:cytology / Q000502:physiology*; D001931:Brain Mapping; D008954:Models, Biological; D009434:Neural Pathways / Q000502:physiology; D009457:Neuroglia / Q000166:cytology / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology; D017711:Nonlinear Dynamics; D012815:Signal Processing, Computer-Assisted; D056969:Voltage-Sensitive Dye Imaging / Q000295:instrumentation / Q000379:methods*