Preoperative embolization of Castleman's disease using microspheres.
Castleman's disease is a rare form of lymph node hyperplasia most commonly presenting as a solitary hypervascular mediastinal mass. Surgical resection is the treatment of choice, but this can be associated with significant blood loss due to its hypervascularity. We report two cases with a preoperative diagnosis of mediastinal Castleman's disease in whom preoperative embolization with Trisacryl gelatin microspheres (Biosphere Medical, Rockland, MA) was performed. Compared with the literature, a decrease in the amount of perioperative bleeding was noted in both cases.
Swee
Warren
W
Department of Radiology, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
Housseini
Ahmed M
AM
Angle
J Fritz
JF
Jones
David R
DR
Daniel
Thomas M
TM
Turba
Ulku C
UC
Abdel-Gawad
Ehab A
EA
Hagspiel
Klaus D
KD
D000293:Adolescent; D001027:Aortography; D001706:Biopsy; D005871:Castleman Disease / Q000175:diagnosis / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008863:Microspheres; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods*; D013908:Thoracotomy / Q000379:methods; D014057:Tomography, X-Ray Computed