[Beware of PET-CT results in cases of cancer occurring in the setting of chronic inflammatory bowel disease].
PET-CT scanning has been proposed as part of the pre-treatment evaluation of GI cancers with equivocal radiologic findings. PET-CT has also been prosposed for the evaluation of patients with chronic inflammatory bowel disease (IBD). We report the case of a patient with IBD and a new diagnosis of rectal cancer; PET-CT overestimated the degree of tumor extension due to false-positive increased uptake in areas of chronic inflammation from IBD. This observation underlines the need for cautious interpretation of PET-CT results for cancer in patients with associated inflammatory illness.
Bonaventure
T
T
Département médico-chirurgical de pathologie digestive, hôpital Lariboisière, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France.
Goéré
D
D
Boige
V
V
Pocard
M
M
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D000328:Adult; D003424:Crohn Disease / Q000150:complications; D003937:Diagnosis, Differential; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D012004:Rectal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome