Single drop microextraction--development, applications and future trends.
Single drop microextraction (SDME) has emerged over the last 10-15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.
Jeannot
Michael A
MA
Department of Chemistry, St. Cloud State University, 366 Wick Science Building, 720 4th Ave. S., St. Cloud, MN 56301-4498, USA. mjeannot@stcloudstate.edu
Przyjazny
Andrzej
A
Kokosa
John M
JM
D005591:Chemical Fractionation / Q000295:instrumentation* / Q000379:methods*; D005544:Forecasting; D009994:Osmolar Concentration; D012997:Solvents / Q000737:chemistry; D013696:Temperature
D012997:Solvents