title: Cardioactive protein-hormonal complexes of brain and heart.
abstract: New cardioactive protein-hormone complexes (PHC) are identified in magnocellular nuclei of hypothalamus. It was proved that they are specific for nervous tissues and are involved in the regulation of metabolic processes of brain and visceral organs, including the heart. PHC dissociate into high-molecular forms which are new specific glycoproteins and the low-molecular cardioactive neurohormones. Results of our own studies on the functional activities of PHC as well as cardioactive peptides in the precardiac and auricular regions of the heart with respect to the parameters of haemostasis system are reviewed.
authors.affiliation: H. Buniatian Institute of Biochemistry, National Academy of Sciences, 5/1 Sevak St., Yerevan, 0014, Republic of Armenia. srapionyanrm@rambler.ru
authors.forename: R M
authors.initials: RM
authors.lastname: Srapionyan
authors.forename: A A
authors.initials: AA
authors.lastname: Galoyan
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D003326:Coronary Circulation; D006023:Glycoproteins / Q000502:physiology*; D006321:Heart / Q000502:physiology; D006728:Hormones / Q000502:physiology*; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D009206:Myocardium / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000502:physiology; D021381:Protein Transport
chemical_list: D006023:Glycoproteins; D006728:Hormones; D018377:Neurotransmitter Agents