title: Pain, referred sensations, and involuntary muscle movements in brachial plexus injury.
abstract: OBJECTIVE
  Examination of the relationship between pain, sensory hypersensitivity, referred sensations and involuntary muscle jerks in patients with brachial plexus injury.
  
  
  METHODS
  Fourteen patients with brachial plexus lesions were included. Spontaneous background and paroxysmal pain and mechanically and thermally evoked pain were recorded. Areas with sensory hypersensitivity and referred pain were mapped on a body chart. This was supplemented by electrophysiological analysis in three patients.
  
  
  RESULTS
  Sensory hypersensitivity and areas with pinprick-induced referred phantom sensations were present in adjacent dermatomes. There was no clear relationship between chronic neuropathic pain and referred sensations, but there was a correlation between pain paroxysms and sensory hypersensitivity in dermatomes adjacent to deafferented areas. In three patients, simultaneous referred sensations and short latency motor action potentials ipsilateral to the denervated side suggested origin at subcortical sites.
  
  
  CONCLUSIONS
  The study suggests a possible role of a spinal generator for sensory hypersensitivity and referred sensations following denervation.
authors.affiliation: Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark. finnerup@ki.au.dk
authors.forename: Nanna B
authors.initials: NB
authors.lastname: Finnerup
authors.forename: C
authors.initials: C
authors.lastname: Norrbrink
authors.forename: A
authors.initials: A
authors.lastname: Fuglsang-Frederiksen
authors.forename: A J
authors.initials: AJ
authors.lastname: Terkelsen
authors.forename: A P
authors.initials: AP
authors.lastname: Hojlund
authors.forename: T S
authors.initials: TS
authors.lastname: Jensen
mesh_terms: D000328:Adult; D001917:Brachial Plexus / Q000293:injuries* / Q000503:physiopathology*; D002908:Chronic Disease; D020820:Dyskinesias / Q000503:physiopathology*; D004576:Electromyography; D019054:Evoked Potentials, Motor; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000503:physiopathology*; D010147:Pain Measurement; D053591:Referred Pain / Q000503:physiopathology*; D010369:Pectoralis Muscles / Q000503:physiopathology; D010812:Physical Stimulation; D013696:Temperature; D013997:Time Factors; D055815:Young Adult