Synthesis of a photo-caged aminooxy alkane thiol.
A photo-caged aminooxy alkane thiol synthesized in 7 steps and 15% overall yield was used to form a self-assembled monolayer (SAM). Photo-deprotection on the surface was confirmed by FT-IR spectroscopy and contact angle goniometry. Conjugation of a small molecule ketone, ethyl levulinate, further confirmed the presence of aminooxy groups on the surface.
Mancini
Rock J
RJ
Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Drive South, Los Angeles, CA 90095-1596, USA.
Li
Ronald C
RC
Tolstyka
Zachary P
ZP
Maynard
Heather D
HD
D000473:Alkanes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D007982:Levulinic Acids / Q000737:chemistry; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013499:Surface Properties
D000473:Alkanes; D007659:Ketones; D007982:Levulinic Acids; D013438:Sulfhydryl Compounds; C542586:ethyl levulinate