[SPECT-CT in sentinel node detection in patients with melanoma].
BACKGROUND
The prognosis of patients with cutaneous melanoma is greatly influenced by the presence of lymph node metastases. One of the most innovative and fascinating concepts to emerge in the field of oncology in recent years is the use of sentinel lymph node biopsy (SLNB).


OBJECTIVE
The aim of this study was to determine what SPECT-CT images contribute to the search for sentinel nodes in patients with melanoma.


METHODS
From March 2007 to October 2008, 18 patients were examined for sentinel nodes using dynamic scintigraphy, planar images, and SPECT-CT in the Nuclear Medicine Department of San Carlos University Hospital. The group contained 10 women and 8 men, age range 14-83 years, mean age 57 years (57+/-20.1).


RESULTS
The sentinel node was located by conventional imaging techniques (dynamic scintigraphy and planar images) in 16 of 18 patients (88.88%). SPECT-CT identified the sentinel node in 18 of 18 patients (100%) and detected clinically relevant findings in 6 of 18 patients (33.33%)


CONCLUSIONS
SPECT-CT imaging contributed clinically relevant information on sentinel nodes of melanoma, which is particularly important in patients with melanoma of the trunk or head and neck.
Mucientes Rasilla
J
J
Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, España. jorgemuci@vodafone.es
Cardona Arboniés
J
J
Delgado Bolton
R
R
Izarduy Pereyra
L
L
Salazar Andía
G
G
Prieto Soriano
A
A
Anula Fernández
R
R
Mayol Martínez
J
J
Lapeña Gutiérrez
L
L
González Maté
A
A
Carreras Delgado
J Luis
JL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed