Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.
The porcine adenovirus NADC-1 isolate, a strain of porcine adenovirus type 4, has a fibre with an atypical architecture. In addition to a classical virus attachment region, shaft and head domains, it contains an additional galectin like domain C-terminal to the head domain and connected to the head domain by a long RGD-containing loop. The galectin-like domain contains two putative carbohydrate-recognition domains. The head and galectin-like domains have been independently crystallized. Diffraction data have been obtained to 3.2 angstrom resolution from crystals of the head domain and to 1.9 angstrom resolution from galectin-like domain crystals.
Guardado-Calvo
Pablo
P
Departamento de Bioquímica y Biología Molecular, Universidad de Santiago de Compostela, Spain.
Llamas-Saiz
Antonio L
AL
Fox
Gavin C
GC
Glasgow
Joel N
JN
van Raaij
Mark J
MJ
D000595:Amino Acid Sequence; D000818:Animals; D003460:Crystallization; D018360:Crystallography, X-Ray; D037161:Galectins / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D011487:Protein Conformation; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013552:Swine; D015678:Viral Structural Proteins / Q000737:chemistry* / Q000235:genetics; D014961:X-Ray Diffraction
D037161:Galectins; D015678:Viral Structural Proteins; C099240:fiber protein NADC-1, Porcine adenovirus