Corollary-and discrepancy-based approaches for examining the appropriateness of premorbid cognitive estimation in geriatric schizophrenia.
OBJECTIVE
This article addresses whether measures for assessing premorbid intellectual functioning are adequate for geriatric schizophrenia.


METHODS
We included geriatric schizophrenia-spectrum disorders (SSD; n = 37), frontotemporal dementia (FTD; n = 41), and geriatric controls (n = 107), and employed measures of verbal ability.


RESULTS
Pearson's correlations and ANOVAs for discrepancy comparisons showed unique patterns of spared function in SSD when compared to FTD and controls.


CONCLUSIONS
Findings lend support to the specificity of cognitive processes in SSD, even when accounting for processes common to the theoretically similar FTD. SSD showed a distinct pattern of spared ability which supports clinical utilization of discrepant measures of premorbid intellectual estimation for SSD.
Foley
Jessica
J
University of California, Los Angeles, David Geffen School of Medicine, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90095, USA. jmfoley@ucla.edu
Golden
Charles
C
Simco
Edward
E
Schneider
Barry
B
McCue
Robert
R
Shaw
Lindsay
L
D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D004569:Electroencephalography / Q000379:methods; D005260:Female; D057180:Frontotemporal Dementia / Q000150:complications / Q000523:psychology; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D049268:Positron-Emission Tomography / Q000379:methods; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology; D013223:Statistics as Topic