title: Structurally diverse limonoids from the fruits of Swietenia mahagoni.
abstract: Eleven new mexicanolide-type limonoids, swietmanins A-I (1-4, 7-11), 2-hydroxy-3-O-isobutyrylproceranolide (5), 2-hydroxy-3-O-benzoylproceranolide (6), and a new andirobin-type limonoid, swietmanin J (12), together with 19 known compounds were isolated from the fruits of Swietenia mahagoni. Their structures were established on the basis of spectroscopic methods. These compounds were evaluated against a small panel of microorganisms.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
authors.forename: Bing-Dong
authors.initials: BD
authors.lastname: Lin
authors.forename: Tao
authors.initials: T
authors.lastname: Yuan
authors.forename: Chuan-Rui
authors.initials: CR
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Dong
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Wu
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Yue
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D005658:Fungi / Q000187:drug effects; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029582:Meliaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004365:Drugs, Chinese Herbal; D036701:Limonins