title: Pancreas transplantation: differences in activity between Europe and the United States.
abstract: BACKGROUND
  Although pancreas transplantation (PT) is the treatment of choice in selected diabetic patients, the International Pancreas Transplant Registry (IPTR) has reported important differences in activity between USA and Europe. Of all cases reported, 75% are from USA and only 23% from Europe. Therefore, an analysis of PT activity in selected European countries (SEC) and USA was performed. Materials and methods. We compared national data reports (2002-06) of deceased donors (DD) and deceased solid organ transplantation (DSOT), with special attention to PT activity from 13 SEC countries (375 million inhabitants) and USA (298 million inhabitants).
  
  
  RESULTS
  The number of PT performed in USA was 2-fold higher than in SEC, with the annual rate >2.4 times higher in USA [5.08-4.64 versus 1.61-1.91 per million population (p.m.p.)]. DD and other DSOT activity rates were only slightly higher in USA. In SEC, important differences in PT activity rate were found between countries in the same year (0-6.21 p.m.p.) and in the same country between different years (6.21-2.47 p.m.p.), unrelated to DD or other DSOT activity rate. PT activity rate increased in SEC from 1.61 to 1.91 p.m.p. but decreased in six countries. The waiting list for PT at the end of 2006 was almost 2-fold higher in USA than in SEC.
  
  
  CONCLUSIONS
  Differences in PT activity rate between 13 SEC countries and USA were not related to DD or other DSOT activity. Different waiting list inclusion criteria or incidence of diabetes complications may be considered in more specific studies.
authors.affiliation: Department of Nephrology, Hospital Universitario de Canarias, Tenerife, Spain. jmgposada@hotmail.com
authors.forename: José
authors.initials: J
authors.lastname: Manuel González-Posada
authors.forename: Domingo
authors.initials: D
authors.lastname: Marrero
authors.forename: Domingo
authors.initials: D
authors.lastname: Hernández
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Coll
authors.forename: Lourdes
authors.initials: L
authors.lastname: Pérez Tamajón
authors.forename: Pedro
authors.initials: P
authors.lastname: Gutiérrez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Martín
authors.forename: Alberto
authors.initials: A
authors.lastname: Bravo
authors.forename: Antonio
authors.initials: A
authors.lastname: Alarcó
authors.forename: Rafael
authors.initials: R
authors.lastname: Matesanz
mesh_terms: D005060:Europe; D006801:Humans; D016035:Pancreas Transplantation / Q000706:statistics & numerical data*; D012042:Registries; D012189:Retrospective Studies; D014019:Tissue Donors; D014481:United States; D014850:Waiting Lists