title: Antimalarial drug development: past to present scenario.
abstract: Malaria is a global health problem that needs attention of drug discovery scientists to investigate novel compounds with high drug efficacy, safety and low cost to counter the malaria parasites that are resistant to existing drug molecules. This is an overview of past to present status of antimalarial drugs including newly researched candidates and also the alternative approaches for the complete control of malaria.
authors.affiliation: Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005, U.P., India. mdanawat.rs.phe@itbhu.ac.in
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Dhanawat
authors.forename: Nirupam
authors.initials: N
authors.lastname: Das
authors.forename: Ramesh C
authors.initials: RC
authors.lastname: Nagarwal
authors.forename: S K
authors.initials: SK
authors.lastname: Shrivastava
mesh_terms: D000634:Aminoquinolines / Q000737:chemistry / Q000494:pharmacology; D000962:Antimalarials / Q000737:chemistry* / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology; D056831:Coordination Complexes / Q000737:chemistry / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005493:Folic Acid Antagonists / Q000737:chemistry / Q000494:pharmacology; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008288:Malaria / Q000188:drug therapy; D017780:Malaria Vaccines / Q000494:pharmacology; D010545:Peroxides / Q000737:chemistry / Q000494:pharmacology; D045568:Tetraoxanes / Q000737:chemistry / Q000494:pharmacology
chemical_list: C503429:1,2,4-trioxane; D000634:Aminoquinolines; D000962:Antimalarials; D001688:Biological Products; D056831:Coordination Complexes; D005493:Folic Acid Antagonists; D006571:Heterocyclic Compounds; D017780:Malaria Vaccines; D010545:Peroxides; D045568:Tetraoxanes