title: Significance of dynamic magnetic resonance sialography in prognostic evaluation of saline solution irrigation of the parotid gland for the treatment of xerostomia.
abstract: OBJECTIVE
  To evaluate the clinical significance of dynamic magnetic resonance (MR) sialographic images in prognostic evaluation of saline solution irrigation of the parotid gland for the treatment of xerostomia.
  
  
  METHODS
  Morphologic findings and functional parameters were evaluated by use of dynamic MR sialography before saline solution irrigation of the parotid gland for the treatment of xerostomia in 17 patients. In addition, the MR sialographic data before the saline solution irrigation treatment in patients with improvement of salivary secretion and the sensation of dry mouth after irrigation treatment were compared with data in patients without improvement.
  
  
  RESULTS
  The maximum changing ratio in the group of patients with improvement after treatment was significantly higher (P = .042) than that in the group of patients without improvement. In addition, high correlations were found between the changing ratio and improvement on the visual analog scale for dry mouth sensation after treatment (Pearson r = 0.63, P = .001) and improvement of salivary flow rate (Pearson r = 0.77, P = .001). Moreover, in 12 patients with improvement of salivary flow rate after the saline solution irrigation treatment, the maximum changing ratio before the saline solution irrigation treatment was over 1.2. However, no significant differences in other parameters, including the detectable ductal area, were found between the group of patients with improvement after treatment and the group without improvement.
  
  
  CONCLUSIONS
  Our study suggests that dynamic MR sialography might be useful for the prognostic evaluation of saline solution irrigation of the parotid gland for the treatment of xerostomia.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science, Kyushu Dental College, Kitakyushu, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Habu
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Taiki
authors.initials: T
authors.lastname: Tomoyose
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ono
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Anzai
authors.forename: Yuu
authors.initials: Y
authors.lastname: Ozaki
authors.forename: Izumi
authors.initials: I
authors.lastname: Yoshioka
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kodama
authors.forename: Noriaki
authors.initials: N
authors.lastname: Yamamoto
authors.forename: Masufumi
authors.initials: M
authors.lastname: Oda
authors.forename: Nao
authors.initials: N
authors.lastname: Wakasugi
authors.forename: Shinobu
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Tetsu
authors.initials: T
authors.lastname: Takahashi
authors.forename: Kiyotoshi
authors.initials: K
authors.lastname: Inenaga
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tominaga
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Morimoto
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000378:metabolism* / Q000473:pathology*; D011336:Probability; D011379:Prognosis; D012463:Saliva / Q000378:metabolism; D012636:Secretory Rate; D012965:Sodium Chloride; D013268:Stimulation, Chemical; D007507:Therapeutic Irrigation; D014987:Xerostomia / Q000628:therapy*
chemical_list: D012965:Sodium Chloride