title: Comparison of postoperative motility in hand-sewn end-to-end anastomosis and functional end-to-end anastomosis: an experimental study in conscious dogs.
abstract: OBJECTIVE
  The objective of this study is to compare the postoperative motility between hand-sewn end-to-end anastomosis and functional end-to-end anastomosis.
  
  
  METHODS
  Fifteen conscious dogs were divided into three groups: normal intact dog group, end-to-end anastomosis group (EE), and functional end-to-end anastomosis group (FEE). In the EE and FEE groups, the dogs underwent a transection of the jejunum 30 cm distal to the Treitz ligament and anastomosis in each method. To compare the gastrointestinal motility, the time to the appearance and the rate of propagation of interdigestive migrating motor contractions (IMC) across the anastomosis, as well as the motility index (MI) at the oral and anal sides of the anastomosis, were measured using strain gauge force transducers. Furthermore, the histological examination of intrinsic nerve fibers was evaluated.
  
  
  RESULTS
  The time to the appearance of propagation of IMC in the EE and FEE was not significantly different. The propagation rates of IMC in the EE and FEE completely recovered within 4 weeks of the surgery. The MI in the EE and FEE was not significantly different. In addition, no continuity of intrinsic nerve fibers across the anastomosis could be identified in either group.
  
  
  CONCLUSIONS
  In the present study, there are no significant differences between the EE and FEE with regard to the time of the appearance and the rate of propagation of IMC. These results suggest that the effect of functional end-to-end anastomosis on postoperative motility is not different from that of hand-sewn end-to-end anastomosis.
authors.affiliation: Department of General Surgical Science (Surgery I), Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi, Gunma, 371-8511, Japan. toyomasu@med.gunma-u.ac.jp
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Toyomasu
authors.forename: Erito
authors.initials: E
authors.lastname: Mochiki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ando
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Yanai
authors.forename: Kyoichi
authors.initials: K
authors.lastname: Ogata
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tabe
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ohno
authors.forename: Ryuusuke
authors.initials: R
authors.lastname: Aihara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D003243:Consciousness; D004285:Dogs; D017615:Enteric Nervous System / Q000503:physiopathology; D005260:Female; D005769:Gastrointestinal Motility; D007583:Jejunum / Q000294:innervation / Q000503:physiopathology / Q000601:surgery*; D010535:Laparoscopy / Q000009:adverse effects; D008297:Male; D016065:Myoelectric Complex, Migrating; D011312:Pressure; D020127:Recovery of Function; D013536:Suture Techniques / Q000009:adverse effects; D013997:Time Factors; D014160:Transducers, Pressure; D016896:Treatment Outcome; D014945:Wound Healing