title: [Organizing pneumonia associated with the use of trastuzumab].
abstract: Organizing pneumonia is a clinical and histological condition in which the onset is usually subacute with respiratory symptoms and pulmonary infiltrates. It may be unknown origin (cryptogenic) or associated with other illnesses, infectious diseases or drugs. We present a 60 year-old female patient with a previous history of breast cancer, who was being treated with trastuzumab, an antiHER2 monoclonal antibody. She was diagnosed with casual pulmonary infiltrates that had histological changes compatible with organizing pneumonia. The pulmonary infiltrates disappeared on withdrawing trastuzumab treatment. Due to the increasing use of biological therapies in different medical areas, we believe it is of interest to report this pulmonary involvement attributed to the monoclonal antibody trastuzumab.
authors.affiliation: Servei d'Oncologia Mèdica, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Universitat Pompeu Fabra, Barcelona, España.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Taus-García
authors.forename: Albert
authors.initials: A
authors.lastname: Sánchez-Font
authors.forename: Sònia
authors.initials: S
authors.lastname: Servitja-Tormo
authors.forename: Lara
authors.initials: L
authors.lastname: Pijuan
authors.forename: José María
authors.initials: JM
authors.lastname: Maiques-Llácer
authors.forename: Víctor
authors.initials: V
authors.lastname: Curull
mesh_terms: D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents / Q000009:adverse effects*; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D000068878:Trastuzumab
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068878:Trastuzumab