title: Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients.
abstract: BACKGROUND
  HIV, HBV and HCV is major public health concerns. Because of shared routes of transmission, HIV-HCV coinfection and HIV-HBV coinfection are common. HIV-positive individuals are at risk of coinfection with HBV and HCV infections. The prevalence rates of coinfection with HBV and HCV in HIV-patients have been variable worldwide depending on the geographic regions, and the type of exposure.
  
  
  OBJECTIVE
  This study aimed to examine HBV and HCV coinfection serologically and determine the shared and significant factors in the coinfection of HIV-positive patients.
  
  
  METHODS
  This descriptive, cross-sectional study was carried out on 391 HIV-positive patients including 358 males and 33 females in Lorestan province, west Iran, to survey coinfection with HBsAg and anti-HCV. The retrospective demographic data of the subjects was collected and the patients' serums were analyzed by ELISA kits including HBsAg and anti-HCV. The collected data was analyzed with SPSS software (15) and Chi-square. Fisher's exact test with 5% error intervals was used to measure the correlation of variables and infection rates.
  
  
  RESULTS
  The results of the study indicated that the prevalence of coinfection in HIV-positive patients with hepatitis viruses was 94.4% (370 in 391), out of whom 57 (14.5%) cases were HBsAg positive, 282 (72%) cases were anti-HCV positive, and 31 (7.9%) cases were both HBsAg and anti-HCV positive.
  
  
  CONCLUSIONS
  There was a significant correlation between coinfection with HCV and HBV and/or both among HIV-positive patients depending on different variables including sex, age, occupation, marital status, exposure to risk factors. (p < 0.001).
authors.affiliation: Department of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khoram Abad, Iran. mohamadi_77@yahoo.com
authors.forename: Mohsen
authors.initials: M
authors.lastname: Mohammadi
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Talei
authors.forename: Ali
authors.initials: A
authors.lastname: Sheikhian
authors.forename: Farzad
authors.initials: F
authors.lastname: Ebrahimzade
authors.forename: Yadollah
authors.initials: Y
authors.lastname: Pournia
authors.forename: Ehsan
authors.initials: E
authors.lastname: Ghasemi
authors.forename: Hadis
authors.initials: H
authors.lastname: Boroun
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies