title: [Determination of mitral valve area in patients with mitral stenosis by the flow-convergence method: clinical application].
abstract: BACKGROUND
  Classic echocardiographic methods to estimate mitral valve area (MVA) in the mitral stenosis (MS) has several limitations. Recently, the proximal isovelocity surface area (PISA) method has been shown to be accurate for calculating MVA.
  
  
  OBJECTIVE
  This study sought to 1) compare the accuracy of the PISA method to planimetry and Doppler pressure half-time (PHT) methods for echocardiographic estimation of MVA and 2) to evaluate the effect of atrial fibrillation (AF) and significant mitral regurgitation (MR) on the accuracy of the PISA method.
  
  
  METHODS
  In 35 patients with rheumatic mitral stenosis, the mitral valve areas were determined by two-dimensional echocardiographic planimetry, pressure half-time and proximal flow convergence region. 19 patients had atrial fibrillation and 15 had associated mitral insufficiency > or = 2.
  
  
  RESULTS
  The correlaton between PISA and planimetry areas was significant (r=0.83, p<.001). The intraclass correlation coefficient was of 0.85 but with a large confidence interval (IC 95% [0,68-0,9]) explaining the significant underestimation of MVA by PISA method: 1,42 +/- 0,47 cm2 versus 1,56 +/- 0,41 cm2 respectively, (p<.001). There was no signicant difference between PISA and PHT areas : 1,42 +/- 0,47 cm2 versus 1,43 +/- 0,46 cm2. Underestimation of MVA par PISA method didn't have real clinical implication: the sensibility of diagnosing severe MS (MVA < or = 1.5 cm2) was 90% vith a negative predictive value of 83%. The correlation was good in patients with AF (r=0,84, p<.001) and with significant MR (r=0,83, p<.001).
  
  
  CONCLUSIONS
  The PISA method may be considered as reliable alternative method for estimation of the MVA in MS. Its accuracy is good in AF and associated MR.
authors.affiliation: Service de Cardiologie, Hôpital des Forces de Sécurité Intérieure, La Marsa.
authors.forename: Lilia
authors.initials: L
authors.lastname: Zakhama
authors.forename: Abdelfatteh
authors.initials: A
authors.lastname: Abed
authors.forename: Elhem
authors.initials: E
authors.lastname: Boussabeh
authors.forename: Besma
authors.initials: B
authors.lastname: Boukhris
authors.forename: Sana
authors.initials: S
authors.lastname: Neffati
authors.forename: Rim
authors.initials: R
authors.lastname: Saad
authors.forename: Ali
authors.initials: A
authors.lastname: Jendoubi
authors.forename: Emna
authors.initials: E
authors.lastname: Bennour
authors.forename: Soraya
authors.initials: S
authors.lastname: BenYoussef
mesh_terms: D000328:Adult; D001281:Atrial Fibrillation / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000473:pathology*; D008944:Mitral Valve Insufficiency / Q000150:complications; D008946:Mitral Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D014463:Ultrasonography