title: Recovery of methamphetamine associated cardiomyopathy predicted by late gadolinium enhanced cardiovascular magnetic resonance.
abstract: Methamphetamine is known to cause a cardiomyopathy which may be reversible with appropriate medical therapy and cessation of use. Late gadolinium enhancement cardiovascular magnetic resonance (CMR) has been shown to identify fibrosis in ischemic and non-ischemic cardiomyopathies. We present a case of severe methamphetamine-associated cardiomyopathy in which cardiac function recovered after 6 months. Evaluation by CMR using late gadolinium enhancement was notable for an absence of enhancement, suggesting an absence of irreversible myocyte injury and a good prognosis. CMR may be useful to predict recovery in toxin-associated non-ischemic cardiomyopathies.
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, One Shields Avenue, Davis, CA 95618, USA.
authors.forename: Javier E
authors.initials: JE
authors.lastname: Lopez
authors.forename: Khung
authors.initials: K
authors.lastname: Yeo
authors.forename: Gary
authors.initials: G
authors.lastname: Caputo
authors.forename: Michael
authors.initials: M
authors.lastname: Buonocore
authors.forename: Saul
authors.initials: S
authors.lastname: Schaefer
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D003287:Contrast Media; D004562:Electrocardiography; D005260:Female; D005355:Fibrosis; D019786:Gadolinium DTPA; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008694:Methamphetamine / Q000009:adverse effects*; D009206:Myocardium / Q000473:pathology*; D011237:Predictive Value of Tests; D020127:Recovery of Function; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000697:Central Nervous System Stimulants; D003287:Contrast Media; D008694:Methamphetamine; D019786:Gadolinium DTPA