Protein surface recognition by dendritic ruthenium(II) tris(bipyridine) complexes.
We report protein surface binding of dendritic ruthenium(ii) tris(bipyiridine) complexes to alpha-chymotrypsin, resulting in a 1 : 1 and 1 : 2 protein complex formation as well as inhibition of the enzyme activity.
Ohkanda
Junko
J
The Institute of Scientific and Industrial Research (ISIR), Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan. johkanda@sanken.osaka-u.ac.jp
Satoh
Ritsuko
R
Kato
Nobuo
N
D015082:2,2'-Dipyridyl / Q000737:chemistry*; D002918:Chymotrypsin / Q000737:chemistry* / Q000378:metabolism; D050091:Dendrimers / Q000737:chemistry*; D019281:Dimerization; D007700:Kinetics; D011485:Protein Binding; D012428:Ruthenium / Q000737:chemistry*; D013499:Surface Properties
D050091:Dendrimers; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D002918:Chymotrypsin; C117608:alpha-chymotrypsin