title: Repair of coronary artery perforation following angioplasty using TachoSil patches.
abstract: Coronary perforation is a rare complication of percutaneous interventional procedures, occurring in 0.2-3% of procedures, which may require emergency coronary bypass surgery. We describe here an alternative method to deal with such complication, which proved effective in a patient with active bleeding from the left anterior descending (LAD) coronary artery. By temporary pressing on beating heart patches of TachoSil, a sponge impregnated with human fibrinogen and thrombin, on the bleeding site, complete and stable hemostasis was achieved.
authors.affiliation: Section of Cardiac Surgery, Cardiac Thoracic and Vascular Department, University of Pisa Medical School, 56124 Pisa, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Celiento
authors.forename: Giovanni
authors.initials: G
authors.lastname: Scioti
authors.forename: Stefano
authors.initials: S
authors.lastname: Pratali
authors.forename: Uberto
authors.initials: U
authors.lastname: Bortolotti
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000293:injuries / Q000601:surgery*; D004322:Drainage; D004338:Drug Combinations; D005260:Female; D005340:Fibrinogen / Q000627:therapeutic use*; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D006489:Hemostatic Techniques; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D012421:Rupture; D013917:Thrombin / Q000627:therapeutic use*; D016896:Treatment Outcome; D014950:Wounds, Penetrating / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*
chemical_list: D004338:Drug Combinations; D006490:Hemostatics; C518955:TachoSil; D005340:Fibrinogen; D013917:Thrombin