title: Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents.
abstract: Iodocyclization of 5-amino-1-(2,4-dinitrophenyl)-1H-4-pyrazolcarboxamides with aromatic aldehydes gave a new series of pyrazolo[3,4-d]pyrimidine derivatives in a single step and their antibacterial activity comparable to Streptomycin as reference drug was evaluated.
authors.affiliation: Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, Vakilabad Blvd 91775-1436 Mashhad, Iran. mbakavoli@yahoo.com
authors.forename: Mehdi
authors.initials: M
authors.lastname: Bakavoli
authors.forename: Ghodsieh
authors.initials: G
authors.lastname: Bagherzadeh
authors.forename: Maryam
authors.initials: M
authors.lastname: Vaseghifar
authors.forename: Ali
authors.initials: A
authors.lastname: Shiri
authors.forename: Mehdi
authors.initials: M
authors.lastname: Pordel
authors.forename: Mansour
authors.initials: M
authors.lastname: Mashreghi
authors.forename: Parvaneh
authors.initials: P
authors.lastname: Pordeli
authors.forename: Maryam
authors.initials: M
authors.lastname: Araghi
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002384:Catalysis; D003500:Cyclization; D007455:Iodine / Q000737:chemistry*; D010084:Oxidation-Reduction; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D011743:Pyrimidines; D007455:Iodine