title: An overview of highly optically pure chloramphenicol bases: applications and modifications.
abstract: Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.
authors.affiliation: Department of Medicinal Chemistry, ShanDong University, Ji'nan, ShanDong, P.R. China.
authors.forename: Kanghui
authors.initials: K
authors.lastname: Yang
authors.forename: Hao
authors.initials: H
authors.lastname: Fang
authors.forename: Jianzhi
authors.initials: J
authors.lastname: Gong
authors.forename: Li
authors.initials: L
authors.lastname: Su
authors.forename: Wenfang
authors.initials: W
authors.lastname: Xu
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002384:Catalysis; D002701:Chloramphenicol / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D002701:Chloramphenicol