title: Does Chlamydia pneumoniae infection trigger to development of asthma in wheezy infants?
abstract: The role of Chlamydia pneumonia (CP) infection in infantile asthma remains obscure. CP infection was serologically determined (Immunoglobulin M antibody titer of index (ID) > or = 2.00) in wheezing infants who were then re-examined at 3 years of age to determine whether asthma is associated with CP infection. Wheezing infants with CP infection progressed to asthma more frequently than those who were not infected. These findings may suggest that CP infection triggers the development of asthma in wheezy infants.
authors.affiliation: Department of Pediatrics, Saga University, 5-1-1 Nabeshima, Saga City 849-8501, Japan. zaitsum@cc.saga-u.ac.jp
authors.forename: Masafumi
authors.initials: M
authors.lastname: Zaitsu
mesh_terms: D000906:Antibodies / Q000097:blood / Q000276:immunology; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001772:Blood Cell Count; D002675:Child, Preschool; D023521:Chlamydophila Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D016993:Chlamydophila pneumoniae; D004804:Eosinophils / Q000166:cytology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D007223:Infant; D008297:Male; D010375:Pedigree; D012135:Respiratory Sounds / Q000503:physiopathology*; D012307:Risk Factors
chemical_list: D000906:Antibodies; D007075:Immunoglobulin M; D007073:Immunoglobulin E