Natural coumarins as a novel class of neuroprotective agents.
Neurodegenerative disorders are a heterogeneous group of diseases and are among the most invaliding syndromes for humans. The aim of this manuscript is to review what has been reported so far in the literature about coumarins as a novel class of pharmacologically active compounds in chemoprevention and/or therapy of these diseases.
Epifano
Francesco
F
Dipartimento di Scienze del Farmaco, Università "G. D'Annunzio" di Chieti-Pescara, Chieti Scalo, Italy. fepifano@unich.it
Curini
Massimo
M
Menghini
Luigi
L
Genovese
Salvatore
S
D003374:Coumarins / Q000737:chemistry* / Q000494:pharmacology; D011564:Furocoumarins / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D018696:Neuroprotective Agents / Q000737:chemistry* / Q000494:pharmacology
C461443:7-isopentenyloxycoumarin; D003374:Coumarins; D011564:Furocoumarins; D018696:Neuroprotective Agents; C105671:fraxetin; C031534:imperatorin