title: Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.
authors.affiliation: Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA. john.carpenter@ucdenver.edu
authors.forename: John F
authors.initials: JF
authors.lastname: Carpenter
authors.forename: Theodore W
authors.initials: TW
authors.lastname: Randolph
authors.forename: Wim
authors.initials: W
authors.lastname: Jiskoot
authors.forename: Daan J A
authors.initials: DJ
authors.lastname: Crommelin
authors.forename: C Russell
authors.initials: CR
authors.lastname: Middaugh
authors.forename: Gerhard
authors.initials: G
authors.lastname: Winter
mesh_terms: D002850:Chromatography, Gel / Q000379:methods* / Q000592:standards; D004355:Drug Stability; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000737:chemistry / Q000592:standards*; D055550:Protein Stability; D011786:Quality Control; D011994:Recombinant Proteins / Q000032:analysis* / Q000737:chemistry / Q000592:standards*
chemical_list: D004364:Pharmaceutical Preparations; D011994:Recombinant Proteins