title: Peri-infarct dysfunction in post-myocardial infarction: assessment of 3-T tagged and late enhancement MRI.
abstract: OBJECTIVE
  To determine LV function at different distances from myocardial infarction (MI) by using 3-T tagged MRI and late gadolinium enhancement (LGE).
  
  
  METHODS
  Cardiac MR images were acquired from 21 patients with previous MI. The harmonic phase (HARP) method was used to calculate radial and circumferential strain (RS, CS). The two strains were synchronised by subtracting the CS from the RS at the same time, and this was defined as the efficient strain (ES). Peak strain (P-RS, P-CS, P-ES) and time to peak strain (T-RS, T-CS, T-ES) were used as estimates of contractile function. Based on the presence of LGE, myocardium was classified into infarct, border zone, adjacent and remote areas.
  
  
  RESULTS
  P-RS and P-ES were significantly greater for remote than for adjacent and infarct areas. P-CS values were significantly greater for remote and border zone than for infarct areas. T-RS and T-ES were significantly shorter for remote and border zone than for infarct areas. T-CS was significantly shorter for border zone than for infarct areas.
  
  
  CONCLUSIONS
  Contractile dysfunction demonstrated by peak strain was correlated with location at different distances from the infarct. In the border zone, contractile deformation was characterised as earlier T-RS, T-CS and T-ES and greater P-CS than in the infarct area.
authors.affiliation: Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon-city, Ehime, 791-0295, Japan. yuinoue@m.ehime-u.ac.jp
authors.forename: Yuma
authors.initials: Y
authors.lastname: Inoue
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Yang
authors.forename: Michinobu
authors.initials: M
authors.lastname: Nagao
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Higashino
authors.forename: Kohei
authors.initials: K
authors.lastname: Hosokawa
authors.forename: Teruhito
authors.initials: T
authors.lastname: Kido
authors.forename: Akira
authors.initials: A
authors.lastname: Kurata
authors.forename: Hideki
authors.initials: H
authors.lastname: Okayama
authors.forename: Jitsuo
authors.initials: J
authors.lastname: Higaki
authors.forename: Teruhito
authors.initials: T
authors.lastname: Mochizuki
authors.forename: Kenya
authors.initials: K
authors.lastname: Murase
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D015897:Comorbidity; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000503:physiopathology*; D011446:Prospective Studies; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA