title: A case of severe cefepime-related neutropenia in a 15-year-old patient.
abstract: We describe the case of a 15-y-old boy with a post-surgical osteoarticular infection, who developed a severe neutropenia after 24 days of treatment with cefepime. Our report suggests that, although rare, severe neutropenia should be considered by clinicians when prescribing cefepime, especially if long-term therapy is expected.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences, Division of Infectious Diseases, University of Perugia, Santa Maria della Misericordia Hospital, Sant'Andrea delle Fratte, Perugia, Italy. lisa.malincarne@unipg.it
authors.forename: Lisa
authors.initials: L
authors.lastname: Malincarne
authors.forename: Daniela
authors.initials: D
authors.lastname: Francisci
authors.forename: Laura
authors.initials: L
authors.lastname: Martinelli
authors.forename: Giulia
authors.initials: G
authors.lastname: Masini
authors.forename: Franco
authors.initials: F
authors.lastname: Baldelli
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D000077723:Cefepime; D002511:Cephalosporins / Q000009:adverse effects* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000139:chemically induced*; D010003:Osteoarthritis / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000077723:Cefepime