The association of dysglycaemia and cardiovascular disease in patients with metabolic syndrome.
The objective of this study was to investigate the relationship between increased prevalence of cardiovascular disease and glucose regulation status in Chinese patients with metabolic syndrome (MetS). All patients underwent an oral glucose tolerance test (2-h post-load plasma glucose) to determine their glucose regulation status and had their brachial-ankle pulse wave velocity (baPWV) measured. Of the 590 patients included in the study, 115 (19.5%) had normal glucose tolerance, 114 (19.3%) had impaired fasting glucose (IFG) alone, 38 (6.4%) had impaired glucose tolerance (IGT) alone, 197 (33.4%) had diabetes mellitus and 126 (21.4%) had combined glucose intolerance (CGI; IFG plus IGT). Patients with diabetes mellitus had a significantly higher baPWV compared with all other groups and patients with CGI had a significantly higher baPWW compared with patients with IFG. Dysglycaemia was common in patients with MetS. An increased prevalence of cardiovascular disease in patients with MetS was related to their glucose regulation status.
Gong
W
W
Department of Endocrinology and Metabolism, HuaShan Hospital, Institute of Endocrinology and Diabetology at Fudan University, Shanghai, China.
Yang
Z
Z
Ye
W
W
Du
Y
Y
Lu
B
B
Wang
M
M
Li
Q
Q
Zhang
W
W
Pan
Y
Y
Feng
X
X
Zhou
W
W
Zhang
Y
Y
Wen
J
J
Yang
Z
Z
Yang
Y
Y
Zhu
X
X
Hu
Renming
R
D055109:Ankle Brachial Index; D001786:Blood Glucose / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000473:pathology*; D005215:Fasting; D005260:Female; D018149:Glucose Intolerance / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors
D001786:Blood Glucose