Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds.
Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.
Shimizu
Junichiro
J
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
Mochida
Kyohei
K
Kobayashi
Yoshiyasu
Y
Kitamura
Masahiko
M
Tanaka
Hiroshi
H
Kishimoto
Miori
M
Lee
Ki-Ja
KJ
Iwasaki
Toshiroh
T
Miyake
Yoh-Ichi
Y
Nakayama
Masanari
M
Yamada
Kazutaka
K
D000818:Animals; D004283:Dog Diseases / Q000378:metabolism / Q000473:pathology*; D004285:Dogs; D005260:Female; D007249:Inflammation / Q000378:metabolism / Q000662:veterinary*; D007405:Intervertebral Disc Displacement / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D008297:Male