title: Nonoperative management of patients with a diagnosis of high-grade small bowel obstruction by computed tomography.
abstract: OBJECTIVE
  To determine the natural history and treatment of high-grade small bowel obstruction (HGSBO). Small bowel obstruction is a frequent complication of abdominal surgery. Complete and strangulating obstructions are managed operatively while partial obstructions receive a trial of nonoperative therapy. The management and outcome of patients with HGSBO diagnosed by computed tomography (CT) has not been examined.
  
  
  METHODS
  Retrospective medical record review. Outcomes for nonoperative vs operative management were analyzed using Fisher exact and log-rank tests.
  
  
  METHODS
  Tertiary care referral center.
  
  
  METHODS
  One thousand five hundred sixty-eight consecutive patients admitted from the emergency department with a diagnosis of small bowel obstruction between 2000 and 2005 by CT criteria.
  
  
  METHODS
  Recurrence of symptoms and complications.
  
  
  RESULTS
  One hundred forty-five patients (9%) with HGSBO were identified, with 88% follow-up (median, 332 days; range, 4-2067 days). Sixty-six (46%) were successfully managed nonoperatively while 79 (54%) required an operation. Length of stay and complications were significantly increased in the operative group (4.7 days vs 10.8 days and 3% vs 23%; P < .001). Nonoperative management was associated with a higher recurrence rate (24% vs 9%; P < .005) and shorter time to recurrence (39 days vs 105 days; P < .005) compared with operative intervention. Computed tomography signs of ischemia, admission laboratory results, and presence of cancer or inflammatory bowel disease were not predictive of an operation.
  
  
  CONCLUSIONS
  Patients with HGSBO by CT can be managed safely with nonoperative therapy; however, they have a significantly higher rate of recurrence requiring readmission or operation within 5 years.
authors.affiliation: Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Flavio G
authors.initials: FG
authors.lastname: Rocha
authors.forename: Todd A
authors.initials: TA
authors.lastname: Theman
authors.forename: Evan
authors.initials: E
authors.lastname: Matros
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Ledbetter
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Zinner
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Ferzoco
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003287:Contrast Media; D013505:Digestive System Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D004636:Emergency Service, Hospital; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging* / Q000209:etiology / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D007421:Intestine, Small / Q000000981:diagnostic imaging* / Q000503:physiopathology; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011336:Probability; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D015996:Survival Rate; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media