title: LASIK for myopia with Aspheric "aberration neutral" ablations using the ESIRIS laser system.
abstract: OBJECTIVE
  To evaluate the clinical outcomes of LASIK using optimized "aberration neutral" ablation profiles.
  
  
  METHODS
  Laser in situ keratomileusis was performed in 231 eyes (120 patients) with a mean spherical equivalent refraction of -4.12+/-2.26 diopters (D) (range: -0.37 to -9.50 D) using a SCHWIND Pendular microkeratome with a 130-microm cutting head and the SCHWIND ESIRIS excimer laser. In all cases, pre- and postoperative autorefractor measurements, manifest refraction, best spectacle-corrected visual acuity (BSCVA), uncorrected visual acuity (UCVA), topography and corneal wavefront analysis, and ocular wavefront analysis as well as complications were analyzed. Ablations were calculated using the ORK-CAM software. Clinical outcomes were evaluated in terms of efficacy, predictability, stability, refractive outcome, safety, and wavefront aberrations.
  
  
  RESULTS
  At 3 months, mean spherical equivalent refraction was -0.10+/-0.33 D (range: +0.86 to -1.18 D). Of 231 eyes, 201 (87%) were within +/-0.50 D of attempted correction. Uncorrected visual acuity was 20/16 or better in 71% (164 eyes), 20/20 or better in 92% (213 eyes), and 20/32 or better in 100%. Average root-mean-square higher order aberrations increased 0.05 microm after treatment, mean spherical aberration increased 0.08 microm after treatment, and mean coma increased 0.04 microm after treatment (all for 6.0-mm analysis diameter).
  
  
  CONCLUSIONS
  Our results show that non-customized "aberration neutral" ablation profiles derived from wavefront analysis are able to minimize the amount of induced aberrations of both the cornea and the eye.
authors.affiliation: Muscat Eye Laser Center, Muscat, Sultanate of Oman. drmaria@omantel.net.om
authors.forename: Maria Clara
authors.initials: MC
authors.lastname: Arbelaez
authors.forename: Camila
authors.initials: C
authors.lastname: Vidal
authors.forename: Bushra Al
authors.initials: BA
authors.lastname: Jabri
authors.forename: Samuel
authors.initials: S
authors.lastname: Arba Mosquera
mesh_terms: D003319:Corneal Stroma / Q000601:surgery; D019781:Corneal Topography; D057108:Corneal Wavefront Aberration / Q000601:surgery*; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D009216:Myopia / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology