title: Protein surface recognition by dendritic ruthenium(II) tris(bipyridine) complexes.
abstract: We report protein surface binding of dendritic ruthenium(ii) tris(bipyiridine) complexes to alpha-chymotrypsin, resulting in a 1 : 1 and 1 : 2 protein complex formation as well as inhibition of the enzyme activity.
authors.affiliation: The Institute of Scientific and Industrial Research (ISIR), Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan. johkanda@sanken.osaka-u.ac.jp
authors.forename: Junko
authors.initials: J
authors.lastname: Ohkanda
authors.forename: Ritsuko
authors.initials: R
authors.lastname: Satoh
authors.forename: Nobuo
authors.initials: N
authors.lastname: Kato
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry*; D002918:Chymotrypsin / Q000737:chemistry* / Q000378:metabolism; D050091:Dendrimers / Q000737:chemistry*; D019281:Dimerization; D007700:Kinetics; D011485:Protein Binding; D012428:Ruthenium / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D050091:Dendrimers; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D002918:Chymotrypsin; C117608:alpha-chymotrypsin