Template synthesis of macrocyclic complexes and their spectroscopic and antibacterial studies.
A new series of macrocyclic complexes of type [M(TML)X]X(2), where M = Cr(III), Fe(III), TML is tetradentate macrocyclic ligand, and X = Cl(-), NO(3)(-), CH(3)COO(-), have been synthesized by condensation of isatin and ethylenediamine in the presence of metal salt. The complexes were synthesized by both conventional and microwave methods. The complexes have been characterized with the help of elemental analysis, conductance measurement, magnetic measurement, and infrared, far infrared, and electronic spectral studies. Molar conductance values indicate them to be 1:2 electrolytes. Electronic spectra along with magnetic moments suggest five-coordinate square pyramidal geometry for these complexes. The complexes were also tested for their in vitro antibacterial activity. Some of the complexes showed satisfactory antibacterial activitiy.
Singh
D P
DP
Department of Chemistry, National Institute of Technology, Kurukshetra, Haryana, India. dpsinghchem@yahoo.co.in
Grover
Vidhi
V
Kumar
Ramesh
R
Jain
Kiran
K
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D005029:Ethylenediamines / Q000737:chemistry; D007510:Isatin / Q000737:chemistry; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D019216:Metals, Heavy / Q000737:chemistry
D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D005029:Ethylenediamines; D047028:Macrocyclic Compounds; D019216:Metals, Heavy; C031234:ethylenediamine; D007510:Isatin