title: Giant cell angiitis of the central nervous system with atypical presentation.
abstract: Giant cell angiitis of the CNS is an uncommon form of vasculitis. Neurological manifestations, both of the peripheral and CNS, are common. The most frequent manifestations are visual loss and stroke. Hemorrhagic onset is uncommon. Most cases have a fatal outcome and a tissue diagnosis is rarely established in life. We describe an unusual case of giant cell angiitis beginning as a hemorrhagic tumoral-like lesion. The results of the histological and ultrastructural analysis have also been reported. Our case illustrates that giant cell angiitis should be considered as a cause of intracerebral hemorrhage, particularly when associated with a relapsing and remitting disease of the CNS.
authors.affiliation: Department of Neurological and Psychiatric Sciences, University of Bari Medical Schoo, Bari, Italy.
authors.forename: Pasqualino
authors.initials: P
authors.lastname: Ciappetta
authors.forename: Pietro Ivo
authors.initials: PI
authors.lastname: D'Urso
authors.forename: Antonio
authors.initials: A
authors.lastname: Colamaria
authors.forename: Enrico
authors.initials: E
authors.lastname: Lauta
authors.forename: Antonia
authors.initials: A
authors.lastname: Cimmino
authors.forename: Oscar Fernando
authors.initials: OF
authors.lastname: D'Urso
authors.forename: Roberta
authors.initials: R
authors.lastname: Rossi
authors.forename: Leonardo
authors.initials: L
authors.lastname: Resta
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ingravallo
mesh_terms: D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000150:complications / Q000473:pathology; D015726:Giant Cells / Q000648:ultrastructure*; D006406:Hematoma / Q000150:complications / Q000473:pathology; D006521:Hepatitis, Chronic / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D046529:Microscopy, Electron, Transmission; D013274:Stomach Neoplasms / Q000150:complications; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000150:complications / Q000473:pathology*