Staphylococcus aureus bacteremia in pediatric patients with cancer.
The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S.aureus (MSSA) in children with cancer has not been well studied. A total of 10 MRSA and 42 MSSA isolates from bacteremic episodes were collected from cancer patients from 2000 through 2007. Seventeen patients (33%) suffered from complications. Thirty-eight (73%) of the bacteremic episodes were catheter-related. Methicillin resistance was associated with increased catheter removal (P = 0.003), but no increase in complications or adverse outcomes was seen.
Srinivasan
Ashok
A
Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. ashok.srinivasan@stjude.org
Seifried
Steven
S
Zhu
Liang
L
Srivastava
Deo K
DK
Flynn
Patricia M
PM
Bankowski
Matthew J
MJ
Shenep
Jerry L
JL
Hayden
Randall T
RT
D000293:Adolescent; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D015373:Bacterial Typing Techniques; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D016106:Methicillin Resistance; D009369:Neoplasms / Q000150:complications*; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D055815:Young Adult
D004269:DNA, Bacterial