Gabapentin therapy for ocular opsoclonus-myoclonus restores eye movement communication in a patient with a locked-in syndrome.
The experience with a patient with locked-in syndrome suffering from opsoclonus-myoclonus symptoms is described: gabapentin successfully reversed the symptoms, just favoring the regaining of eye-dependent communication strategies.
Pistoia
Francesca
F
Hospital San Raffaele, Cassino, Italy. pistoiafrancesca@hotmail.com
Sarà
Marco
M
D000328:Adult; D000588:Amines / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D002544:Cerebral Infarction / Q000150:complications / Q000473:pathology; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D015835:Ocular Motility Disorders / Q000188:drug therapy* / Q000209:etiology; D053578:Opsoclonus-Myoclonus Syndrome / Q000188:drug therapy* / Q000209:etiology; D011149:Pons / Q000473:pathology; D011782:Quadriplegia / Q000150:complications; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin