Angiogenesis in cutaneous disease: part II.
This review will discuss the role of angiogenesis in specific cutaneous diseases. Scientific evidence now points to the role of angiogenesis in tumor development and many other cutaneous disorders. Angiogenesis is a complex process that involves angiogenic growth factors and inhibitors, many of which could be a potential target for pharmacologic intervention. Antiangiogenic agents have recently been applied to dermatologic diseases with promising efficacy.


OBJECTIVE
After completing this learning activity, participants should be able to recognize cutaneous diseases where angiogenesis is likely to be an important factor, recognize scenarios where angiogenic therapy may be useful in conjunction with traditional therapies, and be able to use angiogenic-mediating agents in the treatment of dermatologic disease.
Laquer
Vivian
V
Columbia University College of Physicians, New York, New York, USA.
Hoang
Van
V
Nguyen
Amy
A
Kelly
Kristen M
KM
D043925:Angiogenesis Inducing Agents / Q000378:metabolism; D006801:Humans; D009389:Neovascularization, Pathologic / Q000503:physiopathology*; D012871:Skin Diseases / Q000503:physiopathology*; D012878:Skin Neoplasms / Q000098:blood supply / Q000503:physiopathology; D054079:Vascular Malformations / Q000503:physiopathology
D043925:Angiogenesis Inducing Agents