[Lupus vulgaris as a complication of pulmonary tuberculosis--case report].
Tuberculosis is a contagious disease induced by Mycobacterium species, acid-fast bacilli. These are mostly human type--Mycobacterium tuberculosis, less often cattle type--mycobacterium bovis or other: mycobacterium avium, kansasii, marinom, scrofulaceum, heamophilium, gordonae. The infection can affect all organs, but pulmonary tuberculosis is the most common form. The importance of tuberculosis is definitely rising in the context of massive population migrations in regions affected by its higher incidence, increased HIV infections and AIDS development. Cutaneous tuberculosis is a particular tuberculosis form with differentiated clinical picture. Non-typicalness of skin changes and oligobacilleous course of extrapulmonary tuberculosis forms are repeatedly causing difficulties in adequate diagnosis and early treatment. In differential diagnostics of cutaneous tuberculosis one must take leishmaniasis, actinomycosis, leprosy, syphilis and deep mycosis (among others) into consideration. The study is presenting a case of lupus vulgaris as a complication of past pulmonary tuberculosis. In bacteriological diagnostics of skin changes bioptates, no tuberculosis mycobacteria were found. The disease was diagnosed based on specific granulation presence in histopathology test, tuberculin hypersensivity, bacilli DNA presence in polymerase chain reaction (PCR) test and skin changes regression after anti-mycobacterium treatment. According to authors of the study, the described case confirms the usefulness of PCR nucleonic acids amplification test in cutaneous tuberculosis diagnosis.
Owczarek
Witold
W
Wojskowy Instytut Medyczny w Warszawie, Klinika Dermatologii.
Targowski
Tomasz
T
Kozera-Zywczyk
Anna
A
Paluchowska
Elwira
E
Patera
Janusz
J
D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008177:Lupus Vulgaris / Q000209:etiology* / Q000473:pathology*; D012867:Skin / Q000382:microbiology / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000150:complications*