title: Renal scintigraphy in children with vesicoureteral reflux.
abstract: OBJECTIVE
  To determine the incidence and pattern of abnormal scintigraphy findings in children with UTI and VUR.
  
  
  METHODS
  Data of 118 children who underwent micturating cystourethrography (MCU) and late Tc-99m dimercaptosuccinic acid (DMSA) scan were evaluated. Findings were categorized under the image appearance and relative kidney uptake (RKU) and related to the grade of VUR, sex and child's age.
  
  
  RESULTS
  MCU revealed VUR (78 unilateral and 40 bilateral) of grades I, II, III, IV and V in 2, 47, 35, 19 and 15 patients respectively. There were 52 children with normal and 66 with abnormal DMSA finding. Scarring rate was significantly associated with high grade VUR (p=0.0023) and male gender ( p=0.0412). Bilateral scarring was seen exclusively in children with bilateral VUR. No significant difference was found between renal scarring and child's age in the same gender group. Poor kidney function was shown in 5 patients.
  
  
  CONCLUSIONS
  Renal scarring highly correlated with grade of VUR. A strategy to perform MCU only on patients with abnormal DMSA finding is proposed.
authors.affiliation: Institute of Nuclear Medicine, Military Medical Academy, Belgrade, Serbia. Lilaj@EUnet.rs
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Jaukovic
authors.forename: Boris
authors.initials: B
authors.lastname: Ajdinovic
authors.forename: Marija
authors.initials: M
authors.lastname: Dopudja
authors.forename: Zoran
authors.initials: Z
authors.lastname: Krstic
mesh_terms: D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D016001:Confidence Intervals; D003558:Cystoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D011336:Probability; D011877:Radionuclide Imaging; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D016482:Urinalysis; D014552:Urinary Tract Infections / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology; D014563:Urodynamics; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology
chemical_list: D019783:Technetium Tc 99m Dimercaptosuccinic Acid