Superior ovarian nerve (SON) transection leads to stunted follicular maturation: a histomorphologic and morphometric analysis in the rat model.
Histomorphologic and morphometric effects of peripubertal superior ovarian nerve (SON) transection were evaluated during adult life in rats. Twenty Sprague-Dawley rats were randomly divided into two groups: the SON-transected (SON-t) group (n = 10) and the sham-operated control group (n = 10). Total follicle development was not influenced; however, follicular maturation was seriously stunted by the procedure, as evidenced by significantly thinner theca interna and follicular wall.
Doganay
Melike
M
Department of Gynecology and Obstetrics, Dr. Zekai Tahir Burak Women Health Education and Research Hospital, Ankara, Turkey.
Simsek
Adnan
A
Tapisiz
Omer L
OL
Mulazimoglu
Baris S
BS
Yumusak
Nihat
N
Gungor
Tayfun
T
D000375:Aging; D000818:Animals; D005260:Female; D023421:Models, Animal; D006080:Ovarian Follicle / Q000294:innervation* / Q000473:pathology; D010053:Ovary / Q000294:innervation* / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D046468:Sexual Development; D013562:Sympathectomy