title: Heartworm biology, treatment, and control.
abstract: This article is a review of the systematics, taxonomy, biology, prevention, control, and treatment of the canine heartworm, Dirofilaria immitus. This filarioid parasite remains one of the most important and dangerous diseases of the dog throughout the United States. The geographic range of the parasite is expanding, and in many parts of the country it has emerged as a threat to canine welfare only in the last 50 or so years. The article also discusses the pathophysiological mechanisms behind the disease induced, the means for diagnosing the disease, and the means of assessing the success of therapy. The treatment of potential complications of heartworm infection, such as post-adulticide thromboembolism, eosinophilic granulomatous pneumonitis, and caval syndrome, is also discussed.
authors.affiliation: Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, C4-119 VMC, Tower Road, Ithaca, NY 14853-6401, USA. ddb3@cornell.edu
authors.forename: Dwight D
authors.initials: DD
authors.lastname: Bowman
authors.forename: Clarke E
authors.initials: CE
authors.lastname: Atkins
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D002415:Cats; D009033:Culicidae / Q000469:parasitology; D004183:Dirofilaria immitis / Q000502:physiology*; D004184:Dirofilariasis / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D004283:Dog Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D004285:Dogs; D006801:Humans; D007303:Insect Vectors; D014481:United States / Q000453:epidemiology