Metastatic uterine adenocarcinoma in an 8-year-old gilt.
An 8-y-old gilt was evaluated after the onset of hemorrhagic perineal discharge. Uterine adenocarcinoma with metastases to the lungs and regional lymph nodes was diagnosed at necropsy. Tumor cells lacked expression of estrogen receptor alpha and progesterone receptor. This case represents the first reported uterine adenocarcinoma in a research pig and the first swine uterine neoplasia in which steroid hormone receptor expression was evaluated.
Cannon
Coralie Zegre
CZ
University of North Carolina Department of Pathology and Laboratory Medicine, Chapel Hill, North Carolina, USA.
Godfrey
Virginia L
VL
King-Herbert
Angela
A
Nielsen
Judith N
JN
D000230:Adenocarcinoma / Q000378:metabolism / Q000556:secondary / Q000662:veterinary*; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D047628:Estrogen Receptor alpha / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D007124:Immunoenzyme Techniques / Q000662:veterinary; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary; D008198:Lymph Nodes / Q000473:pathology; D011980:Receptors, Progesterone / Q000378:metabolism; D013552:Swine; D014594:Uterine Neoplasms / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*
D015415:Biomarkers; D047628:Estrogen Receptor alpha; D011980:Receptors, Progesterone; C097314:progesterone receptor B