title: Diagnostic performance of radiographers as compared to radiologists in magnetic resonance colonography.
abstract: OBJECTIVE
  To evaluate the diagnostic performance of radiographers compared to radiologists in the detection of colorectal lesions in MR colonography.
  
  
  METHODS
  159 patients at increased risk of colorectal cancer were included. Four different experienced observers, one MR radiologist, one radiologist in training and two radiographers evaluated all MR colonography examinations. The protocol included T1-weighted and T2-weighted sequences in prone and supine position. Colonoscopy was used as reference standard. Mean sensitivity rates with 95% confidence intervals (CIs) were determined on a per-patient and per-polyp basis, segmented by size (>or= 6mm and >or= 10mm). Specificity was calculated on a per-patient basis. The McNemar and chi-square (chi(2)) test was used to determine significant differences.
  
  
  RESULTS
  At colonoscopy 74 patients (47%) had normal findings; 23 patients had 40 polyps with a size > or = 6mm. In 10 patients at least 1 polyp >or= 10mm was found (20 polyps in total). Similar sensitivities for patients with lesions >or= 10mm were found for radiologists and radiographers (65% (95%CI: 44-86%) vs. 50% (95%CI: 28-72%)) (p=n.s.). For lesions >or=10mm combined per-patient specificity for radiologists and radiographers was 96% (95%CI: 94-98%) and 73% (95%CI: 68-79%) (p<0.0001). Combined per-patient sensitivity for lesions >or=6mm differed significantly between both groups of observers (57% (95%CI: 42-71%) vs. 33% (95%CI: 19-46%)) (p=0.03).
  
  
  CONCLUSIONS
  Radiographers have comparable sensitivity but lower specificity relative to radiologists in the detection of colorectal lesions >or= 10mm at MR colonography. Adequate training in evaluating MR colonography is necessary, especially for readers with no prior experience with colonography.
authors.affiliation: Department of Radiology, Academic Medical Center, Amsterdam, Netherlands. f.m.zijta@amc.uva.nl
authors.forename: F M
authors.initials: FM
authors.lastname: Zijta
authors.forename: J
authors.initials: J
authors.lastname: Florie
authors.forename: S
authors.initials: S
authors.lastname: Jensch
authors.forename: S
authors.initials: S
authors.lastname: Bipat
authors.forename: R A J
authors.initials: RA
authors.lastname: Nievelstein
authors.forename: M
authors.initials: M
authors.lastname: Poulus
authors.forename: M A
authors.initials: MA
authors.lastname: Thomassen-de Graaf
authors.forename: A D
authors.initials: AD
authors.lastname: Montauban van Swijndregt
authors.forename: J
authors.initials: J
authors.lastname: Stoker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000473:pathology*; D003111:Colonic Polyps / Q000175:diagnosis*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D011859:Radiography; D011871:Radiology; D012680:Sensitivity and Specificity; D055815:Young Adult