Neurologic presentations of systemic vasculitides.
Vasculitis or angiitis refers to a group of inflammatory disorders of the blood vessels that cause structural damage to the affected vessel, including thickening and weakening of the vessel wall, narrowing of its lumen, and, usually, vascular necrosis. Systemic vasculitis is classified according to the vessel size and histopathologic and clinical features. Vasculitides with small vessel involvement typically include Henoch-Schönlein purpura and cryoglobulinemia. Polyarteritis nodosa and Wegener granulomatosis are small- and medium-sized vessel vasculitides, whereas temporal arteritis and Takayasu arteritis involve large vessels. In this article, the authors provide a review of the neurologic presentations of the major systemic vasculitides.
Minagar
Alireza
A
Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA. aminag@lsuhsc.ed
Fowler
Marjorie
M
Harris
Meghan K
MK
Jaffe
Stephen L
SL
D001158:Arteries / Q000473:pathology; D001921:Brain / Q000473:pathology; D006801:Humans; D009422:Nervous System Diseases / Q000150:complications* / Q000473:pathology; D056647:Systemic Vasculitis / Q000150:complications* / Q000473:pathology