title: Hormone replacement therapy and successful pregnancy in a patient with premature ovarian failure.
abstract: Premature ovarian failure (POF), premature ovarian insufficiency, premature menopause or hypergonadotropic hypogonadism, a serious life-changing condition that affects young women, remains an enigma and the researcher's challenge. In the present article we described a case of singleton pregnancy in a 33-year-old patient, presenting with POF and treated with hormone replacement therapy. Twenty months later this therapy led to maturation of one follicle, recruitment and fertilisation of the residual oocyte and spontaneous pregnancy ensued. A normal infant was delivered by cesarean section.
authors.affiliation: Gynecology - Obstetrics Clinic 'Narodni front', Belgrade University Medical School, Belgrade, Serbia. stefand@eunet.rs
authors.forename: Svetlana
authors.initials: S
authors.lastname: Dragojević-Dikić
authors.forename: Snezana
authors.initials: S
authors.lastname: Rakić
authors.forename: Branka
authors.initials: B
authors.lastname: Nikolić
authors.forename: Svetlana
authors.initials: S
authors.lastname: Popovac
mesh_terms: D000328:Adult; D002585:Cesarean Section; D004958:Estradiol / Q000627:therapeutic use; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D020249:Hormone Replacement Therapy; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D009640:Norethindrone / Q000031:analogs & derivatives / Q000627:therapeutic use; D000077563:Norethindrone Acetate; D011247:Pregnancy; D016649:Primary Ovarian Insufficiency / Q000188:drug therapy*; D016216:Ultrasonography, Prenatal
chemical_list: D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D000077563:Norethindrone Acetate; D009640:Norethindrone