Marchiafava-Bignami disease: Role of neuroimaging in the diagnosis and management of acute disease.
Marchiafava-Bignami disease (MBD), a rare disorder most commonly seen in patients with a history of alcohol consumption, involves progressive demyelination and subsequent necrosis of the corpus callosum. Because clinical signs are nonspecific, the role of computed tomography and magnetic resonance imaging is essential to confirm the diagnosis. Early diagnosis with imaging and prompt treatment may improve the prognosis of MBD.
Bano
Shahina
S
Department of Radiodiagnosis, Dr. Ram Manohar Lohia Hospital and PGIMER, New Delhi, India. dr_shahinaindia@yahoo.com
Mehra
Shibani
S
Yadav
Sacchida Nand
SN
Chaudhary
Vikas
V
D000208:Acute Disease; D000328:Adult; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D054319:Marchiafava-Bignami Disease / Q000175:diagnosis* / Q000628:therapy*; D015898:Tomography Scanners, X-Ray Computed