title: The physiology behind direct brain oxygen monitors and practical aspects of their use.
abstract: BACKGROUND
  Secondary neuronal injury is implicated in poor outcome after acute neurological insults. Outcome can be improved with protocol-driven therapy. These therapies have largely been based on monitoring and control of intracranial pressure and the maintenance of an adequate cerebral perfusion pressure.
  
  
  CONCLUSIONS
  In recent years, brain tissue oxygen partial pressure (PbtO2) monitoring has emerged as a clinically useful modality and a complement to intracranial pressure monitors. This review examines the physiology of PbtO2 monitors and practical aspects of their use.
authors: Clinical Research Division, Department of Neurosurgery, University of Pennsylvania, 330 S. 9th Street, Philadelphia, PA 19107, USA.
authors: Eileen
authors: E
authors: Maloney-Wilensky
authors: Peter
authors: P
authors: Le Roux
mesh_terms: D000328:Adult; D000818:Animals; D001921:Brain / Q000098:blood supply / Q000502:physiology* / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology; D002648:Child; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods*; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure
chemical_list: D010100:Oxygen