Neural "ignition": enhanced activation linked to perceptual awareness in human ventral stream visual cortex.
Human recognition performance is characterized by abrupt changes in perceptual states. Understanding the neuronal dynamics underlying such transitions could provide important insights into mechanisms of recognition and perceptual awareness. Here we examined patients monitored for clinical purposes with multiple subdural electrodes. The patients participated in a backward masking experiment in which pictures of various object categories were presented briefly followed by a mask. We recorded ECoG from 445 electrodes placed in 11 patients. We found a striking increase in gamma power (30-70 Hz) and evoked responses specifically associated with successful recognition. The enhanced activation occurred 150-200 ms after stimulus onset and consistently outlasted the stimulus presentation. We propose that the gamma and evoked potential activations reflect a rapid increase in recurrent neuronal activity that plays a critical role in the emergence of a recognizable visual percept in conscious awareness.
Fisch
Lior
L
Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel.
Privman
Eran
E
Ramot
Michal
M
Harel
Michal
M
Nir
Yuval
Y
Kipervasser
Svetlana
S
Andelman
Fani
F
Neufeld
Miri Y
MY
Kramer
Uri
U
Fried
Itzhak
I
Malach
Rafael
R
D000328:Adult; D001364:Awareness / Q000502:physiology*; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D011597:Psychomotor Performance / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult