Diffusion-weighted imaging in fetuses with unilateral cortical malformations and callosal agenesis.
DWI was performed in fetuses with callosal agenesis and unilateral cortical malformations. ADC values were retrospectively measured in the developing white matter underlying the cortical malformation and compared with the corresponding contralateral white matter. In all 3 patients, ADC values were lower under the areas of cortical malformation compared with the normal contralateral side. Our findings suggest that there are structural differences in the developing white matter underlying areas of cortical malformation.
Glenn
O A
OA
Department of Radiology and Biomedical Imaging, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA. Orit.Glenn@radiology.ucsf.edu
Quiroz
E M
EM
Berman
J I
JI
Studholme
C
C
Xu
D
D
D055673:Acrocallosal Syndrome / Q000473:pathology*; D000328:Adult; D002540:Cerebral Cortex / Q000002:abnormalities*; D002552:Cerebral Ventricles / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D054220:Malformations of Cortical Development / Q000473:pathology*; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D055815:Young Adult