Giant retroperitoneal liposarcoma with mixed histological pattern: a rare presentation and literature review.
BACKGROUND
Retroperitoneal liposarcoma is a rare tumor that may grow to a considerable size before causing clinical symptoms. Mixed-type retroperitoneal liposarcoma is a very rare clinical entity.


METHODS
We herein describe a rare case of a 54-year-old female who was diagnosed with a giant retroperitoneal liposarcoma arising from the right perinephric space.


RESULTS
Radical nephrectomy and right salpingo-oophorectomy were necessary to achieve complete tumor excision. Histological examination revealed a mixed-type liposarcoma consisting of well-differentiated and pleomorphic elements and deep invasion into the renal parenchyma, which is quite infrequent. The patient was well and disease-free 12 months after surgery.


CONCLUSIONS
Mixed-type retroperitoneal liposarcoma is a rare tumor. Aggressive surgical resection of the tumor together with adjacent structures, if necessary, is the mainstay of treatment.
Salemis
Nikolaos S
NS
2nd Department of Surgery, Army Veterans General Hospital, 10-12 Monis Petraki Str, 15121 Athens, Greece. nikos_salemis@hotmail.com
Tsiambas
Evangelos
E
Karameris
Andreas
A
Tsohataridis
Efstathios
E
D005260:Female; D006801:Humans; D008080:Liposarcoma / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000473:pathology* / Q000601:surgery