Attention K-Mart shoppers: blowout on Aisle 7!
The mechanistic basis of arousal is controversial. In this issue of Neuron, Lebestky et al.'s new study in Drosophila, where dopamine has been shown to be involved in several types of attentional processes, demonstrates that it independently regulates distinct types of arousal. These data provide evidence for molecularly convergent, but anatomically divergent, task-specific arousal circuits.
Griffith
Leslie C
LC
Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454-9110, USA. griffith@brandeis.edu
D000818:Animals; D006801:Humans; D001143:Arousal / Q000235:genetics / Q000502:physiology; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics / Q000502:physiology; D009415:Nerve Net / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D011954:Receptors, Dopamine / Q000235:genetics / Q000502:physiology; D017447:Receptors, Dopamine D1 / Q000235:genetics / Q000502:physiology; D013312:Stress, Physiological / Q000235:genetics / Q000502:physiology
C093147:Dop1R1 protein, Drosophila; D029721:Drosophila Proteins; D011954:Receptors, Dopamine; D017447:Receptors, Dopamine D1