title: Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.
abstract: The chlorinated polyene aurantoic acid (1) and the 4-methylene sterol dehydroconicasterol (2) were isolated from the Indonesian sponge Theonella swinhoei, and their structures were elucidated by interpretation of spectroscopic data. Aurantoic acid is a unique member in the class of naturally occurring conjugated polyene derivatives, while dehydroconicasterol is the likely biogenetic precursor of the major Theonella 4-methylene sterols.
authors: Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy.
authors: Rihab F
authors: RF
authors: Angawi
authors: Barbara
authors: B
authors: Calcinai
authors: Carlo
authors: C
authors: Cerrano
authors: Henny Adeleida
authors: HA
authors: Dien
authors: Ernesto
authors: E
authors: Fattorusso
authors: Fernando
authors: F
authors: Scala
authors: Orazio
authors: O
authors: Taglialatela-Scafati
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011090:Polyenes / Q000737:chemistry / Q000302:isolation & purification*; D047232:Theonella / Q000737:chemistry*
chemical_list: D011090:Polyenes; C546304:aurantoic acid; C546305:dehydroconicasterol; D002784:Cholesterol