title: Changes in bone mineral density of adolescent mothers during the 12-month postpartum period.
abstract: OBJECTIVE
  Bone mineral density (BMD) loss has been described in adult women in the 12-month postpartum period. However, little is known about the precise BMD pattern in adolescent mothers. The present study aimed to evaluate BMD in Argentinean adolescent mothers followed up during the 12-month postpartum period.
  
  
  METHODS
  Analytical, prospective clinical trial. BMD and body composition were determined by dual-energy X-ray absorptiometry; bone mineral content (BMC) and BMD were measured in the lumbar spine (L2-L4), femoral neck (FN), femur trochanter (TR), total hip (TH) and total body. Changes in BMD and BMC were analysed using ANOVA for pairwise comparisons. Other comparisons were performed with the paired-sample t test and Wilcoxon test; Pearson's correlation coefficient was used to analyse the relationship among continuous variables.
  
  
  METHODS
  La Plata, Argentina.
  
  
  METHODS
  Adolescent mothers (n 35; 17 years old or less) were recruited within 15 d after delivery. Studies and follow-up were performed at 15 d and 3, 6 and 12 months postpartum.
  
  
  RESULTS
  BMD and BMC losses at 3 and 6 months and recovery at 12 months fitted a quadratic curve (ANOVA) at the three sites studied (FN, TH, TR), in total-body BMD (P = 0.000) and BMC (P = 0.038). At hip sites, BMD loss occurred at 3 months (FN, P = 0.000; TR, P = 0.000; TH, P = 0.000) and 6 months (FN, P = 0.000; TR, P = 0.000; TH, P = 0.000) compared with basal values. Percentage BMD loss immediately after delivery up to 6 months was about 5 %.
  
  
  CONCLUSIONS
  Adolescents showed significant BMD and BMC losses at 6 months postpartum, with an almost total recovery at 12 months in all sites studied.
authors: Instituto de Desarrollo e Investigaciones Pediátricas Prof. Fernando E. Viteri (IDIP), Hospital de Niños de La Plata (MS/CIC-PBA), 63 N 1069 La Plata CP 1900, Argentina.
authors: Agustina
authors: A
authors: Malpeli
authors: José L
authors: JL
authors: Mansur
authors: Soledad
authors: S
authors: De Santiago
authors: Rosa
authors: R
authors: Villalobos
authors: Alicia
authors: A
authors: Armanini
authors: María
authors: M
authors: Apezteguía
authors: Horacio F
authors: HF
authors: González
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D000704:Analysis of Variance; D001118:Argentina; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006615:Hip; D006801:Humans; D009035:Mothers; D049590:Postpartum Period / Q000502:physiology*; D011446:Prospective Studies