Cardiac Purkinje cells.
Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.
Boyden
Penelope A
PA
Department of Pharmacology, Columbia University, New York, NY, USA. pab4@columbia.edu
Hirose
Masanori
M
Dun
Wen
W
D000200:Action Potentials; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D001283:Atrioventricular Node / Q000502:physiology / Q000503:physiopathology; D002036:Bundle of His / Q000502:physiology / Q000503:physiopathology; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000502:physiology*; D006801:Humans; D009206:Myocardium / Q000166:cytology*; D011690:Purkinje Fibers / Q000166:cytology / Q000502:physiology* / Q000503:physiopathology; D012519:Sarcoplasmic Reticulum / Q000378:metabolism
D015220:Calcium Channels; D002118:Calcium