title: Deficits in the left inferior longitudinal fasciculus results in impairments in object naming.
abstract: The functional characteristics of the left inferior longitudinal fasciculus (ILF) remain unclear. The present study describes a case of a right-handed 74-year-old woman with a brain tumor who showed marked deterioration in object naming ability after invasion of the tumor into the medial region of the left posterior (middle and inferior) temporal lobe just beside the atrium of the lateral ventricle. Diffusion tensor imaging showed possible interruption of the left ILF after invasion of tumor at this site. By contrast, the left superior longitudinal fasciculus (SLF) remained intact after invasion of tumor, and the inferior fronto-occipital fasciculus (IFOF) was already disrupted prior to tumor invasion. These observations indicate that intact ILF function may be required for object naming ability.
authors: Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan. shinoura@cick.jp
authors: Nobusada
authors: N
authors: Shinoura
authors: Yuichi
authors: Y
authors: Suzuki
authors: Masanobu
authors: M
authors: Tsukada
authors: Mizuho
authors: M
authors: Yoshida
authors: Ryozi
authors: R
authors: Yamada
authors: Yusuke
authors: Y
authors: Tabei
authors: Kuniaki
authors: K
authors: Saito
authors: Tomoyuki
authors: T
authors: Koizumi
authors: Kazuo
authors: K
authors: Yagi
mesh_terms: D000368:Aged; D000849:Anomia / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D001254:Astrocytoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D001931:Brain Mapping / Q000379:methods; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D056324:Diffusion Tensor Imaging / Q000379:methods; D004185:Disability Evaluation; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007802:Language; D007807:Language Tests; D008297:Male; D009361:Neoplasm Invasiveness / Q000473:pathology; D009413:Nerve Fibers, Myelinated / Q000502:physiology / Q000648:ultrastructure; D009434:Neural Pathways / Q000473:pathology* / Q000503:physiopathology; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures; D012016:Reference Values; D012086:Reoperation; D013702:Temporal Lobe / Q000473:pathology* / Q000503:physiopathology; D055815:Young Adult