Persistent infection with West Nile virus years after initial infection.
West Nile virus (WNV) RNA was demonstrated in 5 (20%) of 25 urine samples collected from convalescent patients 573-2452 days (1.6-6.7 years) after WNV infection. Four of the 5 amplicons sequenced showed >99% homology to the WNV NY99 strain. These findings show that individuals with chronic symptoms after WNV infection may have persistent renal infection over several years.
Murray
Kristy
K
School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA. Kristy.O.Murray@uth.tmc.edu
Walker
Christopher
C
Herrington
Emily
E
Lewis
Jessica A
JA
McCormick
Joseph
J
Beasley
David W C
DW
Tesh
Robert B
RB
Fisher-Hoch
Susan
S
D000368:Aged; D018450:Disease Progression; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000652:urine*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014901:West Nile Fever / Q000821:virology*; D014902:West Nile virus / Q000235:genetics / Q000302:isolation & purification*
D012367:RNA, Viral