Outcome after bariatric surgery in two adolescents with hypothalamic obesity following treatment of craniopharyngioma.
Treatment of craniopharyngioma (CP) in childhood can lead to severe, debilitating obesity with devastating medical and psychological outcomes. Despite sustained nutritional and exercise-oriented interventions, no efficacious medical option is available for hypothalamic obesity. We describe two adolescents who developed morbid obesity and significant comorbidities following diagnosis and treatment of CP, in whom bariatric surgery was achieved, illustrating a novel approach for symptomatic hypothalamic obesity, as well as positive and negative outcomes.
Rottembourg
Diane
D
Department of Pediatrics, Divisions of Endocrinology, CHU Sainte-Justine, Université de Montréal, Montreal, PQ, Canada. diane.rottembourg@free.fr
O'Gorman
Clodagh S
CS
Urbach
Stacey
S
Garneau
Pierre Y
PY
Langer
Jacob C
JC
Van Vliet
Guy
G
Hamilton
Jill
J
Huot
Céline
C
D000293:Adolescent; D050110:Bariatric Surgery / Q000009:adverse effects / Q000534:rehabilitation; D002648:Child; D003397:Craniopharyngioma / Q000628:therapy*; D005260:Female; D006801:Humans; D007027:Hypothalamic Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008297:Male; D009765:Obesity / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000628:therapy*; D011379:Prognosis; D016896:Treatment Outcome