title: Architecture of intraluminal thrombus removed from abdominal aortic aneurysm.
abstract: Little is known about architecture of intraluminal thrombus (ILT) in abdominal aortic aneurysm (AAA). We present a 74-year-old woman with AAA and high cardiovascular risk. Scanning electron microscopy of ILT removed during surgery showed that its luminal layer is relatively rich in fibrin fibers forming irregular compact structure with low amounts of erythrocytes and platelets, while abluminal portion is composed of densely packed fibrin with caniculi. The structure of ILT may differ largely among AAA patients contrary to previous findings and may reveal large dense fibrin-rich areas deprived of cells, which impair fibrinolysis and stabilize the thrombus size.
authors: Institute of Cardiology, Jagiellonian University School of Medicine, Cracow, Poland.
authors: Paweł
authors: P
authors: Matusik
authors: Piotr
authors: P
authors: Mazur
authors: Ewa
authors: E
authors: Stepień
authors: Roman
authors: R
authors: Pfitzner
authors: Jerzy
authors: J
authors: Sadowski
authors: Anetta
authors: A
authors: Undas
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000473:pathology* / Q000601:surgery; D001792:Blood Platelets; D004912:Erythrocytes; D005260:Female; D005337:Fibrin; D006801:Humans; D008855:Microscopy, Electron, Scanning; D013927:Thrombosis / Q000473:pathology* / Q000601:surgery
chemical_list: D005337:Fibrin