title: Delayed reopening of a hemodynamically significant patent foramen ovale after left lung transplantation: emergency management.
abstract: We report the case of a man who underwent a left-lung transplantation for pulmonary fibrosis and who developed deterioration of his respiratory condition at Day 16 post-operatively, with marked hypoxemia not explained by the usual early respiratory complications of lung transplantation. Contrast-enhanced transthoracic echocardiography identified a patent foramen ovale with massive spontaneous right-to-left shunting. As for the pathogenesis of this right-to-left shunting, we found no evidence supporting an elevation of right-side pressures, with the redirection of the inferior vena cava flow toward the patent foramen ovale being the suspected mechanism. We conclude that delayed reopening of the patent foramen ovale leading to massive right-to-left shunting is a possible complication after lung transplantation.
authors: Service de Pneumologie B et Transplantation Pulmonaire, Hôpital Bichat, Paris, France. herve.mal@bch.aphp.fr <herve.mal@bch.aphp.fr>
authors: Hervé
authors: H
authors: Mal
authors: Giuseppina
authors: G
authors: Biondi
authors: Stephane
authors: S
authors: Gaudry
authors: Florence
authors: F
authors: Arnoult
authors: Jean Michel
authors: JM
authors: Juliard
authors: Pierre
authors: P
authors: Aubry
authors: Eric
authors: E
authors: Brochet
authors: Gaëlle
authors: G
authors: Dauriat
authors: Olivier
authors: O
authors: Brugière
authors: Anne Cécile
authors: AC
authors: Métivier
authors: Gabriel
authors: G
authors: Thabut
authors: Michel
authors: M
authors: Fournier
authors: Michel
authors: M
authors: Wolff
mesh_terms: D054092:Foramen Ovale, Patent / Q000150:complications* / Q000601:surgery; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000601:surgery*