[Cytogenetic effects of cholinotropic preparations mixture on Chironomus plumosus (Diptera) larvae in vivo].
Morphometric analysis of changes in nucleolar organizer (NO), Balbiani rings (BR)--BR(B), BR(1G), BR(2G) and chromosome I arm B puff activities, and in chromosome compactness of Chironomus plumosus (Diptera) polytene chromosomes was carried out in acute period under separate and combined influence of atropine and pilocarpine. Supression effect of cholinotropic preparations mixture was revealed. Suppression of NO activity with atropine concentration increase in the mixture served as criterion of toxicity.
Fedorova
I A
IA
Polukonova
N V
NV
Petrov
N V
NV
D000818:Animals; D001285:Atropine / Q000633:toxicity*; D002683:Chironomidae / Q000166:cytology / Q000187:drug effects* / Q000235:genetics; D019476:Insect Proteins / Q000187:drug effects; D007814:Larva / Q000166:cytology / Q000187:drug effects / Q000235:genetics; D018721:Muscarinic Agonists / Q000633:toxicity*; D018727:Muscarinic Antagonists / Q000633:toxicity*; D009697:Nucleolus Organizer Region / Q000187:drug effects* / Q000648:ultrastructure; D010862:Pilocarpine / Q000633:toxicity*
D019476:Insect Proteins; D018721:Muscarinic Agonists; D018727:Muscarinic Antagonists; D010862:Pilocarpine; D001285:Atropine