Design and fabrication of a low cost implantable bladder pressure monitor.
In the frame of the Flemish Community funded project Bioflex we developed and fabricated an implant for short term (< 7 days) bladder pressure monitoring, and diagnosis of incontinence. This implant is soft and flexible to prevent damaging the bladder's inner wall. It contains a standard flexible electronic circuit connected to a battery, which are embedded in surface treated silicone to enhance the biocompatibility and prevent salt deposition. This article describes the fabrication of the pill and the results of preliminary cytotoxicity tests. The electronic design and its tests, implantation and the result of the in-vivo experimentation will be presented in other articles.
Axisa
F
F
CMST, University of Ghent, Belgium.
Jourand
P
P
Lippens
E
E
Rymarczyk-Machal
M
M
De Smet
N
N
Schacht
E
E
Vanfleteren
J
J
Puers
R
R
Cornelissen
R
R
D004867:Equipment Design / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D011312:Pressure; D019736:Prostheses and Implants; D011474:Prosthesis Design / Q000295:instrumentation* / Q000379:methods; D001743:Urinary Bladder / Q000502:physiology*; D014563:Urodynamics