Fuzzy control for closed-loop, patient-specific hypnosis in intraoperative patients: a simulation study.
Research has demonstrated the efficacy of closed-loop control of anesthesia using bispectral index (BIS) as the controlled variable, and the recent development of model-based, patient-adaptive systems has considerably improved anesthetic control. To further explore the use of model-based control in anesthesia, we investigated the application of fuzzy control in the delivery of patient-specific propofol-induced hypnosis. In simulated intraoperative patients, the fuzzy controller demonstrated clinically acceptable performance, suggesting that further study is warranted.
Moore
Brett L
BL
Texas Tech University Computer Science department, Abilene, TX 79601, USA. brett.moore@gmail.com
Pyeatt
Larry D
LD
Doufas
Anthony G
AG
D000465:Algorithms; D000764:Anesthesia, Closed-Circuit / Q000379:methods; D018686:Anesthetics, Intravenous / Q000494:pharmacology; D003198:Computer Simulation; D004867:Equipment Design; D017143:Fuzzy Logic; D006801:Humans; D006990:Hypnosis; D007432:Intraoperative Period; D015233:Models, Statistical; D016343:Monitoring, Intraoperative; D010363:Pattern Recognition, Automated; D015742:Propofol / Q000493:pharmacokinetics / Q000494:pharmacology*; D012984:Software
D018686:Anesthetics, Intravenous; D015742:Propofol