Lighting up neural networks using a new generation of genetically encoded calcium sensors.
Two improved genetically encoded calcium indicators-based on structure-guided sensor design or on precise subcellular targeting to presynaptic boutons-allow single spikes to be detected in genetically defined populations of neurons and synapses in vivo.
Wilms
Christian D
CD
Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, UK.
Häusser
Michael
M
D000200:Action Potentials; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D051379:Mice; D009415:Nerve Net; D013347:Subcellular Fractions / Q000378:metabolism
D002118:Calcium