Alternaramide, a cyclic depsipeptide from the marine-derived fungus Alternaria sp. SF-5016.
Alternaramide (1), a cyclic pentadepsipeptide, has been isolated from an EtOAc extract of the marine-derived fungus Alternaria sp. SF-5016 by various chromatographic methods. The structure of 1 was mainly determined by analysis of the NMR spectroscopic data, along with chemical methods such as Marfey's and Mosher's methods. Alternaramide (1) showed weak antibiotic activity against Bacillus subtilis and Staphylococcus aureus.
Kim
Min-Young
MY
College of Medical and Life Sciences, Silla University, Busan 617-736, Korea.
Sohn
Jae Hak
JH
Ahn
Jong Seog
JS
Oh
Hyuncheol
H
D000528:Alternaria / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D047630:Depsipeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007723:Korea; D008386:Marine Biology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D047630:Depsipeptides; C545596:alternaramide