[Autoimmune thyroiditis: diagnosis and treatment].
Autoimmune thyroiditis (AIT) is an autoimmune disease with genetic background. Women are more likely to develop AIT. In adulthood, AIT is the most frequent cause for acquired hypothyroidism. Cytotoxic T-lymphocyte antigen (CTL-4) may play a role in the etiology of the disease. Diagnosis is made by determination of elevated antibodies against thyroid peroxidase and thyroglobulin, and a hypoechoic pattern in ultrasound. In case of hypothyroidism a substitutive therapy with levothyroxine is necessary. AIT may occur as postpartum thyroiditis or as a special entity as consequence of therapy with cytokines.
Feldkamp
J
J
Medizinische Klinik I, Klinikum Bielefeld. joachim.feldkamp@klinikumbielefeld.de
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D044963:Biopsy, Fine-Needle; D002648:Child; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D050031:Hashimoto Disease / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D015994:Incidence; D007453:Iodide Peroxidase / Q000276:immunology; D008297:Male; D012307:Risk Factors; D012643:Selenium / Q000627:therapeutic use; D013954:Thyroglobulin / Q000276:immunology; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D013974:Thyroxine / Q000627:therapeutic use
D001323:Autoantibodies; D013954:Thyroglobulin; D007453:Iodide Peroxidase; D012643:Selenium; D013974:Thyroxine