title: 3D ultrasound in assessment of growth and development of frontal lobes in children with perinatal brain injury.
abstract: To investigate the functions of cranial 3D ultrasound in the assessment of growth and development of the volume of frontal lobes in children with perinatal brain injury, 226 neonates of different gestational ages and 86 full term with perinatal brain injury were selected as subjects. The volume of frontal lobe of neonate increased with gestational age within 7 days after birth (r=0.676, P<0.05). The volume of frontal lobe in the 33 children with serious brain injury was lower than that in the control group at 1 month and the difference was significant at 3 and 6 months (P<0.01). There was a correlation between the long-term nervous system dysplasia and the slow increase of frontal lobe volume. The volume of frontal lobe increases with gestational age. The brain injury during the perinatal period affects the development of frontal lobe and is related with neural dysplasia. 3D ultrasound is useful for evaluating the normal and abnormal brain development.
authors: Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China. liuyunfeng96@163.com
authors: Yunfeng
authors: Y
authors: Liu
authors: Congle
authors: C
authors: Zhou
authors: Hongmei
authors: H
authors: Wang
authors: Zezhong
authors: Z
authors: Tang
authors: Haiyan
authors: H
authors: Ding
mesh_terms: D001930:Brain Injuries / Q000000981:diagnostic imaging*; D005625:Frontal Lobe / Q000000981:diagnostic imaging* / Q000254:growth & development / Q000293:injuries*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D009929:Organ Size; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography