title: Who should be offered fetal echocardiography? One center's experience with 3965 cases.
abstract: BACKGROUND
  Although the comprehensive evaluation of the fetal heart includes echocardiography by an experienced pediatric cardiologist, economic constraints sometimes dictate the need to select patients.
  
  
  OBJECTIVE
  To analyze the usefulness of fetal echocardiography in the detection of congenital heart disease according to the referral indication.
  
  
  METHODS
  This retrospective survey relates to all 3965 FE studies performed in our center from January 2000 to December 2004. The diagnosed cardiac anomalies were classified as significant and non-significant malformations. All FE studies were done by a single operator (A.L.) at Meir Medical Center, a referral center for a population of about 400,000. The 3965 FE studies were performed for the following indications: abnormal obstetric ultrasound scans, maternal and family history of cardiac malformations, medication use during the pregnancy, and maternal request. The relative risk of detecting CHD was calculated according to the various referral indications.
  
  
  RESULTS
  Overall, 228 (5.8%) cases of CHD were found. The most common indication for referral was suspicion of CHD during a four-chamber view scan in a basic system survey or during a level II ultrasound survey. No correlation was found between maternal age and gestational age at the time of scanning and the likelihood of finding CHD.
  
  
  CONCLUSIONS
  Our data suggest that a suspicious level II ultrasound orthe presence of polyhydramnios is an important indication for FE in the detection of significant CHD.
authors: Genetic Institute, Meir Hospital-Sapir Medical Center, Kfar Saba, Israel. sharony@clalit.org.il
authors: Reuven
authors: R
authors: Sharony
authors: Moshe D
authors: MD
authors: Fejgin
authors: Tal
authors: T
authors: Biron-Shental
authors: Anat
authors: A
authors: Hershko-Klement
authors: Aliza
authors: A
authors: Amiel
authors: Alex
authors: A
authors: Levi
mesh_terms: D000328:Adult; D003627:Data Interpretation, Statistical; D004452:Echocardiography / Q000379:methods*; D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging*; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D015994:Incidence; D008423:Maternal Age; D018579:Patient Selection; D006831:Polyhydramnios / Q000000981:diagnostic imaging*; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal