Controlled formulation of doxorubicin-polylactide nanoconjugates for cancer drug delivery.
We report here the synthesis of doxorubicin-polylactide conjugate via doxorubicin-initiated lactide polymerization.
Tong
Rong
R
National Institute of Standards and Technology, Boulder, CO 80305, USA.
Tang
Li
L
Yala
Linda
L
Cheng
Jianjun
J
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002626:Chemistry, Pharmaceutical / Q000379:methods; D004317:Doxorubicin / Q000008:administration & dosage*; D004337:Drug Carriers; D016503:Drug Delivery Systems; D015195:Drug Design; D006801:Humans; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy*; D011091:Polyesters / Q000008:administration & dosage*; D011108:Polymers / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
D000970:Antineoplastic Agents; D004337:Drug Carriers; D011091:Polyesters; D011108:Polymers; C033616:poly(lactide); D004317:Doxorubicin