Gold(I)-catalyzed enantioselective [4 + 2]-cycloaddition of allene-dienes.
An enantioselective gold(I)-catalyzed intramolecular [4 + 2]-cycloaddition of allenes and dienes is reported. The reactions allow for the asymmetric synthesis of trans-hexahydroindenes and pyrrolidine products using C(3)-symmetric phosphitegold(I) and ortho-arylphosphoramiditegold(I) complexes as catalysts, respectively.
González
Ana Z
AZ
Department of Chemistry, University of California, Berkeley, MC 1460 Berkeley, California 94720-1460, USA.
Toste
F Dean
FD
D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D000466:Alkadienes; D006046:Gold