A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation.
Dickens
Marina G
MG
Department of Chemistry, Duke University, Durham, NC 27708, USA.
Franz
Katherine J
KJ
D016229:Amyloid beta-Peptides / Q000737:chemistry* / Q000378:metabolism; D002614:Chelating Agents / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008968:Molecular Conformation; D015125:Oxyquinoline / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
D016229:Amyloid beta-Peptides; D002614:Chelating Agents; D015125:Oxyquinoline; D003300:Copper; D006861:Hydrogen Peroxide