Exclusive olive oil consumption is associated with lower likelihood of developing left ventricular systolic dysfunction in acute coronary syndrome patients: the hellenic heart failure study.
OBJECTIVE
The aim of the present work was to evaluate the association between exclusive olive oil consumption and the development of left ventricular systolic dysfunction (LVSD) in patients with a previous acute coronary syndrome (ACS).


METHODS
From 2006 to 2007, 651 consecutive ACS patients were enrolled. In 288 males (64 +/- 13 years) and 75 females (71 +/- 11 years), LVSD (ejection fraction <40%) developed after the cardiac event, and 221 males (62 +/- 11 years) and 69 females (66 +/- 11 years) were without LVSD (ejection fraction >50%). Detailed information regarding their clinical characteristics, anthropometric data, physical activity, smoking and dietary habits (including lipids use) were recorded.


RESULTS
70% of the LVSD patients and 76% of the non-LVSD patients reported exclusive olive oil consumption. Multi-adjusted analysis revealed that exclusive olive oil consumption in post-ACS patients with a first cardiac episode was associated with a 65% (95% confidence interval 0.14-0.87) lower likelihood of developing LVSD after adjusting for various confounders. No significant association was observed among participants with a previous history of ACS.


CONCLUSIONS
Exclusive, long-term olive oil consumption seems to offer significant protection against the development of LVSD in post-ACS patients.
Chrysohoou
Christina
C
First Cardiology Clinic, University of Athens School of Medicine, Greece. chrysohoou@usa.net
Kastorini
Christina-Maria
CM
Panagiotakos
Demosthenes
D
Aggelopoulos
Panagiotis
P
Tsiachris
Dimitris
D
Pitsavos
Christos
C
Stefanadis
Christodoulos
C
D054058:Acute Coronary Syndrome / Q000150:complications* / Q000503:physiopathology; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D004032:Diet; D004041:Dietary Fats / Q000008:administration & dosage; D002149:Energy Intake; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D000069463:Olive Oil; D010938:Plant Oils / Q000008:administration & dosage*; D012307:Risk Factors; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
D004041:Dietary Fats; D000069463:Olive Oil; D010938:Plant Oils