title: Percutaneous vertebroplasty using hydroxyapatite blocks for the treatment of vertebral body fracture.
abstract: Vertebroplasty with hydroxyapatite blocks through a modified percutaneous approach was used to treat 30 patients with vertebral body fractures in 32 vertebral bodies between February 2003 and March 2007. The mean follow-up period was 16.6 months. The pain associated with this procedure, effects on adjacent vertebral bodies, and other complications were evaluated. The rate of recollapse after vertebroplasty was examined in 26 patients with 26 vertebral bodies treated and followed up for more than 3 months. Mean time of operation was 57 minutes and mean number of blocks used per vertebral body was 104. The mean visual analogue scale score was 7.0 preoperatively and 1.6 postoperatively. The mean decline in postoperative vertebral body height was 13%. New vertebral body fractures occurred postoperatively in 3 vertebral bodies in 2 patients. Leakage of blocks outside the vertebral body occurred in 2 patients during the operation, and after the operation in one patient, and the hydroxyapatite plug broke postoperatively in one patient. Hydroxyapatite blocks yielded good pain relief comparable to bone cement, with no serious complications such as a pulmonary embolism or leakage into the spinal canal, and are effective for percutaneous vertebroplasty.
authors: Department of Neurological Surgery, Wakayama Medical University, Wakayama.
authors: Kazuya
authors: K
authors: Nishioka
authors: Shinji
authors: S
authors: Imae
authors: Mari
authors: M
authors: Kitayama
authors: Jun-Ichiro
authors: J
authors: Miki
authors: Toshika
authors: T
authors: Okawa
authors: Toru
authors: T
authors: Itakura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001416:Back Pain / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001672:Biocompatible Materials / Q000009:adverse effects / Q000627:therapeutic use*; D017886:Durapatite / Q000009:adverse effects / Q000627:therapeutic use*; D004868:Equipment Failure / Q000706:statistics & numerical data; D005260:Female; D005548:Foreign-Body Migration / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D010149:Postoperative Pain / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D011655:Pulmonary Embolism / Q000453:epidemiology; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite