[Desmopressin effect on water turnover in suspended rats].
Experiments with 7-day suspended rats had the aim to study water status of postural muscles (m. soleus) and water retention in organism with the use of desmopressin, a synthetic analog of vasopressin. In the condition of gravitational unloading water loss by m. soleus appeared to be considerable, whereas the antidiuretic substance was effective against the loss of equally water and dry mass by the muscle.
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D000818:Animals; D050034:Antidiuretic Agents / Q000627:therapeutic use; D001826:Body Fluids / Q000378:metabolism*; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D003681:Dehydration / Q000209:etiology / Q000378:metabolism* / Q000517:prevention & control; D004195:Disease Models, Animal; D019417:Hindlimb Suspension / Q000009:adverse effects*; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014867:Water / Q000378:metabolism*
D050034:Antidiuretic Agents; D014867:Water; D003894:Deamino Arginine Vasopressin