title: [Effect of Yupingfeng on the level of salivary epidermal growth factor in oral lichen planus].
abstract: OBJECTIVE
  To examine the effect of mouthwash Yupingfeng on the level of salivary epidermal growth factor (sEGF) in oral lichen planus (OLP).
  
  
  METHODS
  The level of sEGF was measured by radioimmunoassay with ligand 125I-EGF. The saliva samples were taken from the normal control group and the OLP patients before and after treatment with Yupingfeng.
  
  
  RESULTS
  The levels of sEGF in OLP patients before treatment with Yupingfeng were (4.09 +/- 3.64) microg/L, which was significantly higher than that in normal control [(2.15 +/- 1.62) microg/L, P = 0.013], and (2.57 +/- 1.19) microg/L after treatment,which was significantly lower than before treatment (P = 0.05).
  
  
  CONCLUSIONS
  Yupingfeng can modulate the level of sEGF in OLP patients.
authors: Institute of Stomatology, Nanjing Medical University & Department of Oral Medicine, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China. fanyuan65@hotmail.com
authors: Yuan
authors: Y
authors: Fan
authors: Juan-Yong
authors: JY
authors: Xu
authors: Qing-Lan
authors: QL
authors: Liu
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004815:Epidermal Growth Factor / Q000378:metabolism*; D005260:Female; D006801:Humans; D017676:Lichen Planus, Oral / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism
chemical_list: D004365:Drugs, Chinese Herbal; C532967:yupingfeng; D004815:Epidermal Growth Factor