title: Transient neonatal myasthenia gravis in a baby born to a mother with new-onset anti-MuSK-mediated myasthenia gravis.
abstract: We describe a 30-year-old pregnant woman with undiagnosed weakness who delivered a severely weak neonate. Subsequent workup of the mother revealed myasthenia gravis with muscle-specific kinase antibodies. The infant responded to intravenous immunoglobulin and symptoms normalized. He was presumed to have an anti-muscle-specific kinase-mediated transient neonatal myasthenia gravis.
authors: University of Tennessee Health Science Center, Memphis, TN, USA. pocarrol@utmem.edu
authors: Peter
authors: P
authors: O'carroll
authors: Tulio E
authors: TE
authors: Bertorini
authors: Glady
authors: G
authors: Jacob
authors: Christopher W
authors: CW
authors: Mitchell
authors: Justin
authors: J
authors: Graff
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007231:Infant, Newborn; D008297:Male; D009157:Myasthenia Gravis / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy; D020941:Myasthenia Gravis, Neonatal / Q000097:blood / Q000188:drug therapy / Q000276:immunology*; D010956:Plasmapheresis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D020794:Receptor Protein-Tyrosine Kinases / Q000276:immunology*; D011950:Receptors, Cholinergic / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D016756:Immunoglobulins, Intravenous; D011950:Receptors, Cholinergic; C095714:MUSK protein, human; D020794:Receptor Protein-Tyrosine Kinases