Metabolic syndrome in patients with atrial fibrillation in the absence of structural heart disease from a tertiary hospital in China.
BACKGROUND
Metabolic syndrome (MetS) and atrial fibrillation (AF) are causally related. This study aimed to determine the prevalence of MetS in patients with AF in the absence of structural heart disease from a tertiary hospital in China.


METHODS
In a single center, 741 inpatients with AF in the absence of structural heart disease prior to catheter ablation were retrospectively reviewed. Among them, 588 (79.4%) patients had paroxysmal AF. Subgroup analyses were performed in paroxysmal AF and persistent/permanent AF.


RESULTS
MetS was found in 343 (46.3%) patients (200 males, 143 females); 0, 1, 2, 3, 4, 5 components of the MetS were found in 59 (8.0%), 140 (18.9%), 199 (26.9%), 203 (27.4%), 103 (13.9%) and 37 (5.0%) patients, respectively. The prevalences of overweight/obesity, high blood pressure, high glucose level, high triglyceride level and low high density lipoproteins cholesterol level were 53.8%, 47.6%, 23.2%, 40.6% and 72.1%, respectively. The prevalence of MetS was not significantly different between the paroxysmal AF group and the persistent/permanent AF group (44.6% vs 52.9%, P = 0.064). The five components of MetS except overweight/obesity (69.3% vs 49.8%, P < 0.001) were not significantly different between the aforementioned two groups. The left atrium diameter increased with the sum of the MetS components. The left atrium diameter in the MetS group was significantly higher than that in the non-MetS group both in patients with paroxysmal AF and in patients with persistent/permanent AF.


CONCLUSIONS
The prevalence of MetS in patients with AF prior to catheter ablation is high. Further study and prevention are needed.
Tang
Ri-bo
RB
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. tangribo1994@yahoo.com.cn
Gao
Ling-yun
LY
Dong
Jian-zeng
JZ
Liu
Xiao-hui
XH
Liu
Xing-peng
XP
Wu
Jia-hui
JH
Long
De-yong
DY
Yu
Rong-hui
RH
Du
Xin
X
Ma
Chang-sheng
CS
D000293:Adolescent; D000328:Adult; D000368:Aged; D001281:Atrial Fibrillation / Q000150:complications*; D017115:Catheter Ablation; D005260:Female; D006331:Heart Diseases / Q000150:complications; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence