title: [Pulmonary fibrosis as a presentation of Wegener's granulomatosis].
abstract: BACKGROUND
  Pulmonary fibrosis secondary to antineutrophil cytoplasmic antibodypositive vasculitis is rarely reported. Most cases have occurred in association with microscopic polyangiitis.
  
  
  METHODS
  We report the case of an 82-year-old man presenting with pulmonary fibrosis. The CT scan showed honeycombing and traction bronchiectasis with peripheral and basal predominance. The diagnosis of Wegener's granulomatosis was based on the association of positive antineutrophil cytoplasmic antibodies, urinary sediment abnormalities and renal biopsy findings.
  
  
  CONCLUSIONS
  We emphasize, through this case, the rarity of interstitial fibrosis as a pulmonary manifestation of vasculitis and we discuss the pathogenesis of this association.
authors: Service de Pneumo-allergologie, CHU Hédi Chaker, Sfax, Tunisie. wajdi.ketata@yahoo.fr
authors: W
authors: W
authors: Ketata
authors: S
authors: S
authors: Msaad
authors: H
authors: H
authors: Gharsalli
authors: K
authors: K
authors: Kammoun
authors: T
authors: T
authors: Abid
authors: S
authors: S
authors: Mrabet
authors: S
authors: S
authors: Makni
authors: T
authors: T
authors: Boudawara
authors: A
authors: A
authors: Ayoub
mesh_terms: D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001706:Biopsy; D003937:Diagnosis, Differential; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis / Q000473:pathology; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007668:Kidney / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D053146:Myeloblastin / Q000276:immunology; D011241:Prednisone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D019268:Antibodies, Antineutrophil Cytoplasmic; D053146:Myeloblastin; D011241:Prednisone