title: Wireless, high-bandwidth recordings from non-human primate motor cortex using a scalable 16-Ch implantable microsystem.
abstract: A multitude of neuroengineering challenges exist today in creating practical, chronic multichannel neural recording systems for primate research and human clinical application. Specifically, a) the persistent wired connections limit patient mobility from the recording system, b) the transfer of high bandwidth signals to external (even distant) electronics normally forces premature data reduction, and c) the chronic susceptibility to infection due to the percutaneous nature of the implants all severely hinder the success of neural prosthetic systems. Here we detail one approach to overcome these limitations: an entirely implantable, wirelessly communicating, integrated neural recording microsystem, dubbed the Brain Implantable Chip (BIC).
authors: Division of Engineering, Brown University, Providence, RI 02912, USA. david.borton@brown.edu
authors: David A
authors: DA
authors: Borton
authors: Yoon-Kyu
authors: YK
authors: Song
authors: William R
authors: WR
authors: Patterson
authors: Christopher W
authors: CW
authors: Bull
authors: Sunmee
authors: S
authors: Park
authors: Farah
authors: F
authors: Laiwalla
authors: John P
authors: JP
authors: Donoghue
authors: Arto V
authors: AV
authors: Nurmikko
mesh_terms: D000669:Amplifiers, Electronic; D000703:Analog-Digital Conversion; D000818:Animals; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D019054:Evoked Potentials, Motor / Q000502:physiology*; D006801:Humans; D008904:Miniaturization; D009044:Motor Cortex / Q000502:physiology*; D011323:Primates; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*