title: Alternative option in the treatment of very small ruptured intracranial aneurysms.
abstract: BACKGROUND
  To evaluate the safety and protective effect of relative undersized coil with loose coil core in the clinical dilemma condition--very small (43.0 mm) ruptured intracranial aneurysm.
  
  
  METHODS
  We studied 12 patients (4 men, 8 women) who had suffered from acute ruptured small intracranial aneurysms (2-3 mm in size, with SAH presentation). All subjects underwent a single coil embolization procedure. An undersized coil (equivalent to the neck size or 0.5 mm smaller than the aneurysm diameter) was chosen as the embolizer. Based on the postembolization angiogram, subjects were divided into 2 groups. One was labeled as the initial complete obliteration group (NR) and the other as the incomplete obliteration group (SR). Fisher exact test and the Wilcoxon rank sum test were used to for statistical analysis.
  
  
  RESULTS
  The technical success rate was 100% without any procedure-related complication. The follow-up interval ranged from 6 to 32 months. No episode of rebleeding or coil migration could be defined in the admissive and following period. Loose coil core were seen in all patients. The total recurrent rate was 8.3% (1/12); only one patient suffered from recurrent lesion in SR group.
  
  
  CONCLUSIONS
  The preliminary result showed that under-sized coil packing with loose coil core could provide the protective effect and prevent from further rebleeding for very small ruptured aneurysms. It should be considered as an alternative option in the treatment of acute ruptured very small aneurysms when other conventional strategies are not feasible.
authors: Department of Radiology, China Medical University Hospital, Taichung 404, Taiwan. onecowyang@yahoo.com.tw
authors: Ming-Shiang
authors: MS
authors: Yang
authors: Ho-Fai
authors: HF
authors: Wong
authors: Tzu-Hsien
authors: TH
authors: Yang
authors: Yao-Liang
authors: YL
authors: Chen
authors: Si-Wa
authors: SW
authors: Chan
authors: Huey-Jen
authors: HJ
authors: Lee
authors: Yung Wei
authors: YW
authors: Tung
authors: Chung-Wei
authors: CW
authors: Tu
authors: Tai-Yi
authors: TY
authors: Chen
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D001807:Blood Vessel Prosthesis / Q000706:statistics & numerical data* / Q000639:trends; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D002985:Clinical Protocols; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011182:Postoperative Care; D055502:Secondary Prevention; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome