title: A case of atopic dermatitis-associated lichen amyloidosis successfully treated with oral cyclosporine and narrow band UVB therapy in succession.
abstract: Lichen amyloidosis (LA) is a chronic, severely pruritic skin disease characterized by deposition of amyloid in the skin with no visceral involvement. Current treatments of LA are unsatisfactory, with high relapse rates, complications, and treatment failures. A 31-year-old woman with a history of refractory atopic dermatitis (AD) presented with pruritic, multiple, discrete papules on the extremities and back. Histopathologic examination confirmed the diagnosis of LA. A treatment regimen of oral cyclosporine and subsequent narrow band UVB (NBUVB) for a total of 8 months resulted in nearly complete regression. Although further studies are required to define the exact mechanism of action of this treatment regimen (oral cyclosporine + NBUVB), it seems to be an effective alternative in treating patients with LA and/or AD-associated LA.
authors: Department of Dermatology, Kangnam St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors: Min Ju
authors: MJ
authors: Kang
authors: Hei Sung
authors: HS
authors: Kim
authors: Hyung Ok
authors: HO
authors: Kim
authors: Young Min
authors: YM
authors: Park
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D014467:Ultraviolet Therapy
chemical_list: D003879:Dermatologic Agents; D016572:Cyclosporine