Larvicidal activity of compounds isolated from Asarum heterotropoides against Culex pipiens pallens, Aedes aegypti, and Ochlerotatus togoi (Diptera: Culicidae).
The toxicity of several compounds isolated from Asarum heterotropoides root steam distillate to third-instar larvae of Culex pipiens pallens Coquillett, Aedes aegypti (L.), and Ochlerotatus togoi Theobald was examined using a direct contact mortality bioassay. Safrole was the most toxic constituent to Cx. p. pallens and Ae. aegypti larvae, whereas terpinolene was most toxic to Oc. togoi. However, LC50 values of these three mosquito larvae to both essential oils as well as the remainder of the 26 compounds identified in A. heterotropoides were considerably greater than for fenthion or temephos. However, we suggest that constituents of A. heterotropoides root steam distillate merit further study as potential mosquito larvicides due to global efforts to reduce the level of highly toxic synthetic pesticides in the aquatic environment.
Perumalsamy
Haribalan
H
Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Republic of Korea.
Kim
Nam-Jin
NJ
Ahn
Young-Joon
YJ
D000330:Aedes / Q000254:growth & development*; D000818:Animals; D030023:Asarum / Q000737:chemistry*; D003465:Culex / Q000254:growth & development*; D007306:Insecticides; D007814:Larva; D007928:Lethal Dose 50; D044969:Ochlerotatus / Q000254:growth & development*; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry
D007306:Insecticides; D009822:Oils, Volatile