RETRACTED: miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

This article has been retracted at the request of the editors. This article was published on December 8, 2009. In November 2021, The Ohio State University notified the Cancer Cell editors that this article contains ten instances of plagiarized text; that Figures 1G, 5B, 5E, 7D, and 7F were falsified; and that part of Figure 1G in the article is the same as part of Figure 1B in another article that was later retracted (Garofalo et al., 2008, PLOS One 3, e4070, https://doi.org/10.1371/journal.pone.0004070). The university recommended the editors correct or retract the article. Given the extent and severity of these issues, the editors are retracting the article. S.-S. S. agrees with the retraction, and M.G., G.D.L., G.N., F.P., P.S., P.G., G.C., and C.M.C. disagree with the retraction; all other authors couldn't be reached or didn't respond.
Garofalo
Michela
M
Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
Di Leva
Gianpiero
G
Romano
Giulia
G
Nuovo
Gerard
G
Suh
Sung-Suk
SS
Ngankeu
Apollinaire
A
Taccioli
Cristian
C
Pichiorri
Flavia
F
Alder
Hansjuerg
H
Secchiero
Paola
P
Gasparini
Pierluigi
P
Gonelli
Arianna
A
Costinean
Stefan
S
Acunzo
Mario
M
Condorelli
Gerolama
G
Croce
Carlo Maria
CM
D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology; D015536:Down-Regulation / Q000502:physiology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D035683:MicroRNAs / Q000502:physiology*; D051059:PTEN Phosphohydrolase / Q000502:physiology*; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000502:physiology*; D019717:Tissue Inhibitor of Metalloproteinase-3 / Q000502:physiology*
D035683:MicroRNAs; D051059:PTEN Phosphohydrolase; D053221:TNF-Related Apoptosis-Inducing Ligand; D019717:Tissue Inhibitor of Metalloproteinase-3; C525709:MIR221, human; C525710:MIR222, human; C088390:TIMP3 protein, human; C505653:TNFSF10 protein, human; C494929:PTEN protein, human