title: Differential expression of three labial genes during earthworm head regeneration.
abstract: The earthworm provides an excellent model for investigating regeneration. Here we report the full-length cloning of three labial genes (Pex-lab01, Pex-lab02, and Pex-lab03) in the earthworm Perionyx excavatus. To analyze their expression pattern during head and tail regeneration, we used the reverse transcription-polymerase chain reaction. Our results indicate that the three labial genes were expressed only in the head-regenerating tissues. Also, we found that the expression of Pex-lab01 and Pex-lab02 is up-regulated, and this indicates their involvement in wound healing and the blastema formation processes during early head regeneration.
authors: Department of Life Science, Chung-Ang University, Seoul, Republic of Korea. sjcho71_cns@berkeley.edu
authors: Sung-Jin
authors: SJ
authors: Cho
authors: Ki Seok
authors: KS
authors: Koh
authors: Eun
authors: E
authors: Lee
authors: Soon Cheol
authors: SC
authors: Park
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005786:Gene Expression Regulation; D006257:Head / Q000502:physiology*; D018398:Homeodomain Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D009835:Oligochaeta / Q000235:genetics* / Q000502:physiology*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012038:Regeneration / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013623:Tail / Q000502:physiology
chemical_list: D018076:DNA, Complementary; D018398:Homeodomain Proteins; D012333:RNA, Messenger