Poromas and porokeratosis in a patient treated for solid-organ and haematological malignancies.
We describe a patient with previous solid-organ (testicular, oesophageal) and haematological (acute myeloid leukaemia) malignancies, in whom chronic cutaneous graft-versus-host disease was complicated by poromas and porokeratosis. Chemotherapy, total body irradiation, longstanding immunosuppression and ultraviolet radiation may all have played a part in the pathogenesis of the skin tumours.
Sherman
V
V
Department of Dermatology, Churchill Hospital, Oxford, UK. victoria.j.sherman@doctors.org.uk
Reed
J
J
Hollowood
K
K
Littlewood
T
T
Burge
S M
SM
D000328:Adult; D006086:Graft vs Host Disease / Q000150:complications; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D016609:Neoplasms, Second Primary / Q000209:etiology*; D017499:Porokeratosis / Q000209:etiology*; D057091:Poroma / Q000209:etiology*; D013544:Sweat Gland Neoplasms / Q000209:etiology*; D013724:Teratoma / Q000628:therapy; D013736:Testicular Neoplasms / Q000601:surgery