Renal function status in patients with primary osteoporosis (type 2).
BACKGROUND
Several studies correlate renal function with lower bone mineral density (BMD); however, the relationship between early stages of renal dysfunction and BMD has not been clearly defined. Our objective was to determine renal function in patients with primary osteoporosis (type 2) and its relationship with BMD.


METHODS
Patients with primary osteoporosis diagnosed using DEXA were evaluated in this cross-sectional analysis. Renal function was estimated according to the modification of diet in renal disease (MDRD) equation and classified according to the National Kidney Foundation for chronic kidney disease (CKD). The relationship between renal function and BMD was analyzed.


RESULTS
Included in the study were 120 women with a mean age 67.9 + or - 6.56 years. There was a positive relationship between spine BMD and moderate affection of renal function (F = 4.860, p = 0.009). No relationship was found between hip BMD or fracture with renal function (p = 0.223).


CONCLUSIONS
Although women with poor renal function have significantly lower spine BMD, no relationship between early stages of CKD and low BMD has been demonstrated.
Nava-Bringas
Tania Inés
TI
Servicio de Rehabilitación de Columna, Instituto Nacional de Rehabilitación, México, D.F., Mexico. taniamedusa@hotmail.com
Chávez-Arias
Daniel David
DD
del Pilar Diez-García
María
M
Miranda-Duarte
Antonio
A
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000465:Algorithms; D015519:Bone Density; D002118:Calcium / Q000378:metabolism; D003404:Creatinine / Q000097:blood; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D005598:Fractures, Spontaneous / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000254:growth & development / Q000503:physiopathology*; D007677:Kidney Function Tests; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D010758:Phosphorus / Q000378:metabolism; D014807:Vitamin D / Q000031:analogs & derivatives / Q000378:metabolism
D004164:Diphosphonates; D014807:Vitamin D; D010758:Phosphorus; C104450:25-hydroxyvitamin D; D003404:Creatinine; D002118:Calcium