title: Endoscopic treatment of dieulafoy lesions and risk factors for rebleeding.
abstract: OBJECTIVE
  Dieulafoy lesions are an important cause of upper gastrointestinal bleeding. The purpose of this study was to assess the efficacy of endoscopic treatment for these lesions and to identify the possible predictive factors for rebleeding associated with clinical and endoscopic characteristics.
  
  
  METHODS
  Records from 44 patients admitted with Dieulafoy bleeding between January 2006 and December 2007 were reviewed. We retrospectively analyzed the clinical and endoscopic findings and then correlated the rebleeding risk factors with Dieulafoy lesions.
  
  
  RESULTS
  Primary hemostasis was achieved by endoscopic treatment in 39 patients (88.6%). There were no significant differences between the rebleeding and non-rebleeding groups with respect to age, gender, initial hemoglobin levels, presence of shock, concurrent disease, location of bleeding, or initial hemostatic treatment methods. However, the use of non-steroidal anti-inflammatory drugs or anticoagulants (p=0.02) and active stages in the Forrest classification (p<0.01) were risk factors for rebleeding after endoscopic therapy.
  
  
  CONCLUSIONS
  Endoscopic therapy is effective and safe for treating Dieulafoy lesions, and it has both short- and long-term benefits. Early identification of risk factors such as the use of non-steroidal anti-inflammatory drugs or anticoagulants and the Forrest classification of bleeding predict the outcome of Dieulafoy lesions.
authors: Department of Internal Medicine, Pusan National University College of Medicine, Seo-gu, Busan, Korea.
authors: Won
authors: W
authors: Lim
authors: Tae Oh
authors: TO
authors: Kim
authors: Su Bum
authors: SB
authors: Park
authors: Ha Rin
authors: HR
authors: Rhee
authors: Jin Hyun
authors: JH
authors: Park
authors: Jung Ho
authors: JH
authors: Bae
authors: Hong Ryeul
authors: HR
authors: Jung
authors: Mi Ra
authors: MR
authors: Kim
authors: NaRiA
authors: N
authors: Lee
authors: Sun Mi
authors: SM
authors: Lee
authors: Gwang Ha
authors: GH
authors: Kim
authors: Jeong
authors: J
authors: Heo
authors: Geun Am
authors: GA
authors: Song
mesh_terms: D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000150:complications / Q000628:therapy*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D016558:Hemostasis, Endoscopic / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors