title: [Exploratory study on the association between high iodine intake and lipid].
abstract: OBJECTIVE
  To explore the association between excessive iodine intake and lipid disorder in human bodies.
  
  
  METHODS
  Based on the NTTST sample survey on water iodine in Suining of Jiangsu province, this study involved 81 residents whose drinking water containing excessive iodine and 101 residents who drank water with normal iodine content. Blood samples were tested and compared on lipids (TG, TC, HDL-C, LDL-C, apoA1, apoB) between the two groups, after adjusting the influences of age and gender. The study also compared the abnormal rate of each lipid indicator between the two groups. Corresponding RR values and 95% confidence interval were calculated. Correlation between iodine content in drinking water and blood lipid was also studied.
  
  
  RESULTS
  apoA1 in the group with excessive iodine intake was significantly lower than that in the normal iodine group, while there were no significant differences between the two groups in other lipid indicators. The abnormal rate of HDL-C of excess iodine group (16.88%) was significantly higher than the rate of normal iodine group (7.22%) while there were no significant differences between the two groups in other lipid indicators. Both apoA1 and HDL-C in the excess iodine group had a negative correlation with water iodine, while the other indicators of two groups had no correlation with water iodine.
  
  
  CONCLUSIONS
  Drinking water with excess iodine might increase the risk of lipid disorder.
authors: Yuzhong District Center for Disease Control and Prevention, Chongqing, China.
authors: Miao
authors: M
authors: Liu
authors: Su-Mei
authors: SM
authors: Li
authors: Xiu-Wei
authors: XW
authors: Li
authors: Pei-Hua
authors: PH
authors: Wang
authors: Ping
authors: P
authors: Liang
authors: Shu-Hua
authors: SH
authors: Li
mesh_terms: D016632:Apolipoprotein A-I / Q000097:blood*; D002681:China; D008076:Cholesterol, HDL / Q000097:blood*; D016001:Confidence Intervals; D006801:Humans; D007455:Iodine / Q000009:adverse effects / Q000032:analysis*; D052439:Lipid Metabolism Disorders / Q000209:etiology*; D012306:Risk; D014881:Water Supply / Q000032:analysis*
chemical_list: D016632:Apolipoprotein A-I; D008076:Cholesterol, HDL; D007455:Iodine