Toxicology: pearls and pitfalls in the use of antidotes.
Although most poisonings require only supportive care, the emergency physician must recognize when the use of an antidote is required, and understand the risks and benefits of the treatment rendered. Although the more commonly instituted specific therapy in acute poisoning is the administration of intravenous fluids followed by the administration of oxygen, in certain circumstances prompt administration of a specific antidote may be required, and failure to identify these circumstances may lead to significant morbidity or mortality. This article describes select antidotes, and discusses their indications and potential pitfalls.
Smollin
Craig G
CG
University of California-San Francisco, Department of Emergency Medicine, 505 Parnassus Avenue, San Francisco, CA 94143-0208, USA. craig.smollin@emergency.ucsf.edu
D000931:Antidotes / Q000627:therapeutic use*; D062787:Drug Overdose / Q000175:diagnosis / Q000188:drug therapy; D004636:Emergency Service, Hospital; D006801:Humans; D011041:Poisoning / Q000175:diagnosis* / Q000188:drug therapy*; D012909:Snake Bites / Q000628:therapy
D000931:Antidotes