title: Choroidal vitiligo masquerading as large choroidal nevus: a report of four cases.
abstract: OBJECTIVE
  To describe 4 patients with choroidal vitiligo masquerading as large choroidal nevus.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Observational case series of 4 patients.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Clinical features.
  
  
  RESULTS
  Four patients referred with the diagnosis of large choroidal nevus were found to have unilateral (n = 1) or bilateral (n = 3) extensive patchy choroidal depigmentation classified as choroidal vitiligo. There was no evidence of choroidal nevus, and the pigmented "lesion" proved to be normal choroidal pigment surrounded by a region of pigment absence (vitiligo). There was no evidence of ocular inflammation or related retinal or retinal pigment epithelial changes. The choroidal vitiligo was clinically flat and measured 12 to 24 mm diameter, involving the post-equatorial fundus in all cases. There were no related anterior segment abnormalities. Cutaneous vitiligo was present in all cases. There was no documented progression of the choroidal or cutaneous vitiligo over a maximum 2-year follow-up.
  
  
  CONCLUSIONS
  Choroidal vitiligo is an idiopathic benign process that can involve large segments of the posterior choroid, leaving only patches of residual choroidal pigment, simulating, in reverse, a large choroidal nevus.
  
  
  BACKGROUND
  The author(s) have no proprietary or commercial interest in any materials discussed in this article.
authors: Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. carol.shields@shieldsoncology.com
authors: Carol L
authors: CL
authors: Shields
authors: Aparna
authors: A
authors: Ramasubramanian
authors: W Benjamin
authors: WB
authors: Kunz
authors: Ekta
authors: E
authors: Aggarwal
authors: Jerry A
authors: JA
authors: Shields
mesh_terms: D000368:Aged; D015862:Choroid Diseases / Q000175:diagnosis*; D002830:Choroid Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000175:diagnosis*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014820:Vitiligo / Q000175:diagnosis*