title: One-step synthesis and bioassay of N-phosphoramidophosphonates.
abstract: A simple one-step synthesis was accomplished for the preparation of N-phosphoramidophosphonates by a direct reaction of phosphoramidate (1) with heterocyclic aldehydes (2a-j) and dialkyl phosphites at 60-70 degrees C in the presence of tetramethylguanidine. The tetramethylguanidine not only catalyses this reaction but also helps to form pure products in high yields in lesser time. They exhibited good insecticidal and antioxidant properties.
authors: Department of Chemistry, Sri Venkateswara University, Tirupati, India.
authors: Mudumala
authors: M
authors: Veera Narayana Reddy
authors: Avula
authors: A
authors: Balakrishna
authors: Mungara Anil
authors: MA
authors: Kumar
authors: Gangireddygari Chandra Sekhar
authors: GC
authors: Reddy
authors: Arigela Uma Ravi
authors: AU
authors: Sankar
authors: Cirandur Suresh
authors: CS
authors: Reddy
authors: Tirupati Murali
authors: TM
authors: Krishna
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001681:Biological Assay / Q000379:methods*; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D010756:Phosphoric Acids / Q000138:chemical synthesis* / Q000737:chemistry; D018411:Spodoptera / Q000187:drug effects*
chemical_list: D000577:Amides; D000975:Antioxidants; D007306:Insecticides; D010756:Phosphoric Acids; C011067:phosphoramidic acid