Stretchable bioelectrodes.
In this paper, we present a stretchable electrode array for studying cell behavior subjected to mechanical strain. The electrode array consists of four gold nail-head pins (250 microm tip diameter and 1.75 mm spacing) inserted into a polydimethylsiloxane (PDMS) platform (25.4 x 25.4mm(2)). Fusible indium alloy (liquid at room temperature) filled microchannels are used to connect the electrodes to the outside, thus providing the required stretchability. The electrode platform is biocompatible and can withstand strains of up to 40%. We tested these electrodes by repeatedly (100 times) subjecting them to 35% strain and did not notice any failure. We also successfully cultured mice cardiomyocytes onto the platform and performed electrical pacing.
Ziaie
B
B
School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907 USA. bziaie@purdue.edu
D055119:Elastic Modulus; D017097:Electric Impedance; D004566:Electrodes; D004852:Epoxy Compounds / Q000737:chemistry*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D004852:Epoxy Compounds; D011108:Polymers; C520895:SU-8 compound