The chemistry and biology of LL-37.
LL-37 is a human host defence peptide that has a wide range of biological functions, including antimicrobial and immunomodulatory properties. This review summarises how molecular structure influences the balance between the immunomodulatory and antimicrobial functions of LL-37.
Burton
Matthew F
MF
Centre for Bioactive Chemistry, Department of Chemistry, University of Durham, Science Laboratory, South Road, Durham, DH1 3LE, UK. m.f.burton@durham.ac.uk
Steel
Patrick G
PG
D000595:Amino Acid Sequence; D023181:Antimicrobial Cationic Peptides; D006801:Humans; D008969:Molecular Sequence Data; D054804:Cathelicidins
D023181:Antimicrobial Cationic Peptides; D054804:Cathelicidins