title: Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China.
abstract: Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.
authors: The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
authors: Honglin
authors: H
authors: Chen
authors: Chung Lam
authors: CL
authors: Cheung
authors: Hung
authors: H
authors: Tai
authors: Pengxi
authors: P
authors: Zhao
authors: Jasper F W
authors: JF
authors: Chan
authors: Vincent C C
authors: VC
authors: Cheng
authors: Kwok Hung
authors: KH
authors: Chan
authors: Kwok Yung
authors: KY
authors: Yuen
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000494:pharmacology*; D024882:Drug Resistance, Viral; D005260:Female; D006723:Hong Kong; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects*; D009154:Mutation; D009439:Neuraminidase / Q000037:antagonists & inhibitors* / Q000235:genetics; D053139:Oseltamivir / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir; D009439:Neuraminidase