[Treatment of allergic rhinitis with nasal mometasone furoate].
OBJECTIVE
To evaluate the effects of nasal mometasone furoate on moderate to severe allergic rhinitis.


METHODS
Patients with moderate to severe allergic rhinitis were enrolled and received mometasone furoate nasal spray 200 microg once daily for four weeks. Four hundreds and sixty-three patients completed the study. We weekly interviewed the patients to evaluate the symptoms, and the affection of disease on night sleep and daily life. Mini Rhinoconjunctivitis Quality of Life Questionnaire (Mini-RQLQ) and Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) were used to evaluate the quality of life.


RESULTS
The individual and total symptomatic scores of week 1, week 2 and week 4 decreased compared with baseline. The scores of Mini-RQLQ and NRQLQ of week 1, week 2 and week 4 decreased compared with baseline too. The scores of the next visit were significantly lower than those of the previous visit (P < 0.01).


CONCLUSIONS
A four-week administration of mometasone furoate nasal spray can effectively treat allergic rhinitis.
Zhang
Luo
L
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otorhinolaryngology, Beijing, 100730 China.
Xu
Geng
G
Wang
Xiang-dong
XD
Liu
Shi-xi
SX
Li
Yuan
Y
Wang
Shen-qing
SQ
Yang
Bei-bei
BB
Zheng
Chun-quan
CQ
Wang
Cheng-shuo
CS
Dong
Pin
P
Lin
Zi-ping
ZP
Zhang
Hua
H
Han
De-min
DM
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000368:Aged; D018926:Anti-Allergic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068656:Mometasone Furoate; D011244:Pregnadienediols / Q000008:administration & dosage / Q000627:therapeutic use*; D011788:Quality of Life; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D011795:Surveys and Questionnaires; D055815:Young Adult
D018926:Anti-Allergic Agents; D011244:Pregnadienediols; D000068656:Mometasone Furoate