title: Pyomyositis in children: early diagnosis and treatment.
abstract: OBJECTIVE
  This study was conducted to evaluate early diagnosis, clinical course, and treatment outcome in children with pyomyositis.
  
  
  METHODS
  Between 2001 and 2006, 6 children with a mean age of 7.2 years were diagnosed and treated for pyomyositis in our clinic. The most common site of involvement was the hip and thigh region. All patients underwent early magnetic resonance imaging (MRI) examination that played a significant role in the early diagnosis and management of the disease.
  
  
  RESULTS
  Staphylococcus aureus was the most common pathogen and was identified in 3 cases. Intravenous antibiotics were administered and were followed by oral agents for an additional period. The duration of therapy ranged from 3 to 6 weeks. No surgical intervention was needed. Magnetic resonance imaging was used to evaluate response to the therapy.
  
  
  CONCLUSIONS
  Although pyomyositis is a rare disease, it should be considered in the differential diagnosis of immediate onset of musculoskeletal pain in children. Early diagnosis and antibiotic treatment are important as major complications such as abscess formation and sepsis can be avoided. Having a high sensitivity to reactive inflammatory changes, MRI is a valuable tool in the armamentarium of the clinician in early diagnosis of pyomyositis.
authors: Department of Orthopedic Surgery, University of Ioannina School of Medicine, 45110 Ioannina, Greece. mitsionis@otenet.gr
authors: Gregory I
authors: GI
authors: Mitsionis
authors: Gregory N
authors: GN
authors: Manoudis
authors: Marios G
authors: MG
authors: Lykissas
authors: Ioanna
authors: I
authors: Sionti
authors: Eustathios
authors: E
authors: Motsis
authors: Anastasios D
authors: AD
authors: Georgoulis
authors: Alexandros E
authors: AE
authors: Berisa
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002444:Cefuroxime / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004009:Dicloxacillin / Q000627:therapeutic use; D004322:Drainage / Q000379:methods; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D052880:Pyomyositis / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification; D016896:Treatment Outcome; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin; D004009:Dicloxacillin; D002444:Cefuroxime