Theoretical study for the treatment of pancreatic cancer using electric pulses.
Through the development of numerical models, this study describes how Non-Thermal Irreversible Electroporation (N-TIRE) of the pancreas presents certain challenges that can be alleviated through the use of non-puncturing plate electrodes and ultra-short electric pulses.
Arena
Christopher B
CB
School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA 24060, USA. carena@vt.edu
Rylander
Marissa Nichole
MN
Davalos
Rafael V
RV
D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D004599:Electric Stimulation Therapy / Q000379:methods*; D004574:Electromagnetic Fields; D006801:Humans; D008954:Models, Biological; D010179:Pancreas / Q000503:physiopathology* / Q000528:radiation effects; D010190:Pancreatic Neoplasms / Q000503:physiopathology* / Q000628:therapy*; D011829:Radiation Dosage; D013813:Therapy, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome