[Influence of sperm from different sources on the clinical outcome of intracytoplasmic sperm injection].
OBJECTIVE
To analyze the clinical outcomes of intracytoplasmic sperm injection (ICSI) with spermatozoa from different sources.


METHODS
We retrospectively studied the rates of fertilization, clinical pregnancy, implantation, abortion, ectopic pregnancy and delivery in 682 patients treated by ICSI, who were divided according to the sperm sources into an ejaculated sperm group (ES, n = 598), a percutaneous epididymal sperm aspiration (PESA, n = 58) and a testicular sperm extraction (TSE, n = 26).


RESULTS
The fertilization rate was significantly lower in the TSE than in the ES and PESA groups (81.06% vs 87.95% and 87.82%, P < 0.05). But no statistically significant differences were observed among the ES, PESA and TSE groups in the rates of clinical pregnancy (39.46%, 48.28% and 34.62%), implantation (19.80%, 23.80% and 18.34%), abortion (13.13%, 17.86% and 11.11%), ectopic pregnancy (5.51%, 7.14% and 11.11%) and delivery (32.11%, 36.21% and 26.92%) (P > 0.05).


CONCLUSIONS
Although TSE-obtained sperm affect the rate of fertilization, those obtained by TSE and PESA do not obviously influence the outcome of clinical pregnancy.
Song
Cheng
C
Center of Assisted Reproductive Techniques, Shenzhen Zhongshan Urology Hospital, Shenzhen, Guangdong 518001, China. songcheng128@163.com
Zeng
Yong
Y
Hu
Xiao-dong
XD
Cheng
Jin-quan
JQ
Huang
Ju
J
Huang
Li-shi
LS
Zhang
Wei
W
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D053625:Sperm Retrieval; D013094:Spermatozoa