Rate of cardiovascular recovery to combined or separate orthostatic and mental challenges.
Post stress neurovascular responses induced by physical and mental stress are poorly understood. We investigated the time course of cardiovascular and autonomic recovery, induced by orthostatic and mental challenge, using passive head up tilt (HUT) and mental arithmetic (MA), respectively, when applied singly (MA, HUT) or in combination (MA+HUT). Fifteen healthy males participated in three protocols: HUT, MA and combined MA+HUT, with sessions randomized and 2 weeks apart. Post stress responses were studied in the first 10 min (early; cardiovascular only) and 30 min (late), in 2.5 min epochs. A detailed analysis of early period was done in 30s epochs. Within the first 2.5 min recovery, time courses of heart rate, stroke volume and cardiac output differed significantly, particularly when comparing HUT vs. MA and MA+HUT vs. MA. Additionally, heart rate response differed in HUT vs. MA+HUT. No differences in hemodynamic recovery were seen during the next 2.5 min. Late responses of heart rate and cardiac output showed significantly lower values as compared to baseline, especially for HUT and MA+HUT. Recovery of hemodynamic responses, either due to single or combined stress challenges, showed stressor- and time-dependent patterns. Our data provide useful information regarding why longer recovery periods must be assessed and provide novel insights regarding recovery of physical and mental stressors. This may have clinical implications in the development of cardiovascular diseases such as hypertension or myocardial ischemia.
Goswami
Nandu
N
Institute of Physiology, Center of Physiological Medicine, Medical University, Graz, Austria. Nandu.goswami@meduni-graz.at
Lackner
Helmut Karl
HK
Papousek
Ilona
I
Jezova
Daniela
D
Hinghofer-Szalkay
Helmut
H
Montani
Jean-Pierre
JP
D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D000704:Analysis of Variance; D004244:Dizziness; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D018475:Head-Down Tilt / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D010465:Perception / Q000502:physiology; D012647:Self-Assessment; D013312:Stress, Physiological / Q000502:physiology*; D013315:Stress, Psychological / Q000503:physiopathology*; D018667:Tilt-Table Test; D013997:Time Factors