Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog.
An 8-year-old, castrated male, miniature wire-haired dachshund was presented with a 4-month history of intermittent facial twitching (myoclonus). The myoclonic episodes progressed over a 16-month period. Generalized seizure activity was infrequent. Clinical examination revealed visually stimulated myoclonus. Response to therapy with antiepileptic drugs was equivocal. Genetic testing identified the dog as being affected by Lafora disease.
Webb
Aubrey A
AA
Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, 3330 Hospital Drive, NW, Calgary, Alberta T2N 4N1. webba@ucalgary.ca
McMillan
Chantal
C
Cullen
Cheryl L
CL
Boston
Sarah E
SE
Turnbull
Julie
J
Minassian
Berge A
BA
D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D004285:Dogs; D020022:Genetic Predisposition to Disease; D020192:Lafora Disease / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000662:veterinary*; D008297:Male
D000927:Anticonvulsants