title: Advances in molecular and "-omics" technologies to gauge microbial communities and bioremediation at xenobiotic/anthropogen contaminated sites.
abstract: Microbial bioremediation has been well-demonstrated as an ecofriendly and cost-competitive strategy for elimination of xenobiotic and or anthropogenic compounds from the polluted environments. However, successful execution of these versatile bioremediation strategies requires a thorough understanding of factors governing the growth, metabolism, dynamics and functions of indigenous microbial communities at contaminated sites. Recent innovative breakthroughs in genotypic profiling, ultrafast genome pyrosequencing, metagenomics, metatranscriptomics, metaproteomics and metabolomics along with bioinformatics tools have provided crucial in-sights of microbial communities and their mechanisms in bioremediation of environmental pollutants. Moreover, advances in these technologies have significantly improved the process of efficacy determination and implementation of microbial bioremediation strategies. The current review is focused on application of these molecular and "-omics" technologies in gauging the innate microbial community structures, dynamics and functions at contaminated sites or pollution containment facilities.
authors: BRD School of Biosciences, Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India. chirayurdesai@gmail.com
authors: Chirayu
authors: C
authors: Desai
authors: Hilor
authors: H
authors: Pathak
authors: Datta
authors: D
authors: Madamwar
mesh_terms: D001673:Biodegradation, Environmental; D015374:Biosensing Techniques; D001709:Biotechnology / Q000379:methods* / Q000639:trends; D019295:Computational Biology / Q000379:methods; D003362:Cost-Benefit Analysis; D004785:Environmental Pollutants; D023281:Genomics; D005838:Genotype; D017404:In Situ Hybridization, Fluorescence; D009696:Nucleic Acids / Q000737:chemistry; D020411:Oligonucleotide Array Sequence Analysis; D012335:RNA, Ribosomal / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014873:Water Pollutants / Q000737:chemistry; D015262:Xenobiotics / Q000737:chemistry*
chemical_list: D004785:Environmental Pollutants; D009696:Nucleic Acids; D012335:RNA, Ribosomal; D014873:Water Pollutants; D015262:Xenobiotics