Outcomes of conservative therapy for young women with early endometrial adenocarcinoma.
Four of six patients with endometrial cancer had initial response to progesterone therapy and obtained complete response; three among them had successful pregnancies with three live births. The results suggest that progesterone therapy, combined with assisted reproductive technology, provides more chance of carrying a full-term pregnancy for patients with endometrial adenocarcinoma.
Mao
Yuyan
Y
Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
Wan
Xiaoyun
X
Chen
Yaxia
Y
Lv
Weiguo
W
Xie
Xing
X
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005298:Fertility / Q000187:drug effects*; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000627:therapeutic use*; D019290:Megestrol Acetate / Q000627:therapeutic use*; D009367:Neoplasm Staging; D011247:Pregnancy; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies; D016896:Treatment Outcome
D018931:Antineoplastic Agents, Hormonal; D017258:Medroxyprogesterone Acetate; D019290:Megestrol Acetate