Behçet's disease in a patient with myelodysplastic syndrome.
A 75-year-old man presented with painful oral and groin ulcers. The lack of any infections and the location of the ulcers suggested Behçet's disease. Subsequently, pancytopenia developed and bone marrow examination revealed myelodysplastic syndrome. Cytogenetic examination revealed 7q- and 20q- but not 8+. Immunosuppressive therapy with cyclosporine and corticosteroid resulted in a dramatic improvement in both clinical signs and hematologic abnormalities.
Kovacs
Erzsebet
E
Division of Rare Diseases, Second Department of Medicine, University of Debrecen Medical and Health Science Centre, Debrecen, Hungary.
Nemeth
Hajnalka
H
Telek
Bela
B
Ujfalusi
Aniko
A
Balogh
Erzsebet
E
Pasztor
Eva
E
Pfliegler
Gyorgy
G
D000368:Aged; D001528:Behcet Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D014314:Trisomy