The physiology behind direct brain oxygen monitors and practical aspects of their use.
BACKGROUND
Secondary neuronal injury is implicated in poor outcome after acute neurological insults. Outcome can be improved with protocol-driven therapy. These therapies have largely been based on monitoring and control of intracranial pressure and the maintenance of an adequate cerebral perfusion pressure.


CONCLUSIONS
In recent years, brain tissue oxygen partial pressure (PbtO2) monitoring has emerged as a clinically useful modality and a complement to intracranial pressure monitors. This review examines the physiology of PbtO2 monitors and practical aspects of their use.
Maloney-Wilensky
Eileen
E
Clinical Research Division, Department of Neurosurgery, University of Pennsylvania, 330 S. 9th Street, Philadelphia, PA 19107, USA.
Le Roux
Peter
P
D000328:Adult; D000818:Animals; D001921:Brain / Q000098:blood supply / Q000502:physiology* / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology; D002648:Child; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods*; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure
D010100:Oxygen