title: [Simple screening method for judging the complex formation between drug and aluminum (III)].
abstract: We examined a simple screening method for judging the complex formation between a drug and aluminum(III) on a spot plate. As few drug had color reaction by basing on the binary complex formation of drug-aluminum(III), the ternary complex formation of drug-aluminum(III)-dye was studied this time using 50 kinds of drugs. The dyes used were Chromazurol S and Erythrosin. As a result, in the drug that the complex formation with aluminum(III) was assumed, a remarkable coloration difference was recognized in comparison with the blank prepared under the same conditions. The proposed simple screening method should be very useful for judging instantly the complex formation between a drug and aluminum(III).
authors: Department of Hospital Pharmacy School of Medicine, Kinki University, Osaka-Sayama, Japan.
authors: Kanako
authors: K
authors: Miyachi
authors: Masahiro
authors: M
authors: Nakao
authors: Hisashi
authors: H
authors: Kurokawa
authors: Mayu
authors: M
authors: Tomida
authors: Shinichiro
authors: S
authors: Kamino
authors: Kenzo
authors: K
authors: Moriyama
authors: Takako
authors: T
authors: Yamaguchi
authors: Yoshikazu
authors: Y
authors: Fujita
mesh_terms: D000535:Aluminum / Q000032:analysis*; D003124:Colorimetry / Q000379:methods*; D056831:Coordination Complexes / Q000032:analysis*; D004923:Erythrosine; D062385:Hydroxybenzoates; D007202:Indicators and Reagents; D004364:Pharmaceutical Preparations / Q000032:analysis*
chemical_list: D056831:Coordination Complexes; D062385:Hydroxybenzoates; D007202:Indicators and Reagents; D004364:Pharmaceutical Preparations; C015076:chrome azurol S; D000535:Aluminum; D004923:Erythrosine