title: Identification of markers of cardiovascular disease in women and the reconstruction of its corresponding protein interaction network.
abstract: Cardiovascular disease is the second most prevalent cause of morbidity and mortality in women of developed countries. Although it is well established that gender is a risk factor for cardiovascular disease, most gene expression analysis studies favour the identification of disease bio-markers and potential drug targets over combined populations. This study integrates genomic and systems approaches to identify a female-related set of genes that intervene in signal and metabolic pathways leading to cardiovascular disease.
authors: School of Computing, University of East Anglia, Norwich, NR4 7TJ, England, UK. a.camargo-rodriguez@uea.ac.uk
authors: A
authors: A
authors: Camargo
authors: J T
authors: JT
authors: Kim
mesh_terms: D015415:Biomarkers; D001698:Biomedical Engineering; D002318:Cardiovascular Diseases / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D020869:Gene Expression Profiling; D005819:Genetic Markers; D006801:Humans; D053858:Metabolic Networks and Pathways; D025941:Protein Interaction Mapping; D049490:Systems Biology
chemical_list: D015415:Biomarkers; D005819:Genetic Markers