title: Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.
abstract: BACKGROUND
  Spinal canal metastasis secondary to gestational trophoblastic neoplasia (GTN) is a rare condition.
  
  
  METHODS
  A 21-year-old female presented with symptoms of cauda equina compression by an extradural metastasis from GTN. The patient received multiagent chemotherapy combined with intrathecal methotrexate administration. Her neurologic symptoms improved remarkably after the cessation of chemotherapy. During the 21-month follow-up period, she was asymptomatic and has shown overall improvement in well-being.
  
  
  CONCLUSIONS
  Spinal canal metastasis of GTN is a possibility that must be considered in young women with a history of hydatidiform mole who have neurologic symptoms or signs, which were improved completely by chemotherapy alone in this case.
authors: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, and Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
authors: Fengzhi
authors: F
authors: Feng
authors: Yang
authors: Y
authors: Xiang
authors: Yang
authors: Y
authors: Cao
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood / Q000187:drug effects; D003609:Dactinomycin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage; D031901:Gestational Trophoblastic Disease / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology* / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000008:administration & dosage; D011247:Pregnancy; D013115:Spinal Canal / Q000473:pathology; D013125:Spinal Neoplasms / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D014594:Uterine Neoplasms / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D014750:Vincristine / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005467:Floxuridine; D003609:Dactinomycin; D014750:Vincristine; D005047:Etoposide; D008727:Methotrexate