title: Restoring three-dimensional magnetic resonance angiography images with mean curvature motion.
abstract: OBJECTIVE
  The management of neurovascular disease requires precise information on the cerebral vascular anatomy. Digital subtraction angiography (DSA) is the gold standard against which other imaging modalities have to be measured. To improve the quality of three-dimensional (3D) magnetic resonance angiography (MRA) images, we present a novel concept in 3D image analysis.
  
  
  METHODS
  Five patients, harboring cerebral aneurysm, underwent DSA, computed tomography angiography (CTA) and MRA. MRA data were processed using a novel anisotropic curvature motion model. Three-dimensional reconstructions of CTA and MRA datasets were used for comparison.
  
  
  RESULTS
  The 3D-reconstructed images accurately displayed all aneurysms. The anatomy of the anterior part of the circle of Willis was visualized reliably. The smoothened vessel surfaces enhanced the readability of the images. Regarding visual representation of the posterior part of the circle of Willis, the post-processed MRA showed the arterial segments less accurate than the standard modalities.
  
  
  CONCLUSIONS
  This new approach is a promising tool for planning of neurovascular interventions and preoperative evaluation.
authors: Department of Neurosurgery, University of Bonn Medical Center, Bonn, Germany.
authors: Claudia
authors: C
authors: Schlimper
authors: Oliver
authors: O
authors: Nemitz
authors: Ulrich
authors: U
authors: Dorenbeck
authors: Jasmin
authors: J
authors: Scorzin
authors: Ross
authors: R
authors: Whitaker
authors: Tolga
authors: T
authors: Tasdizen
authors: Martin
authors: M
authors: Rumpf
authors: Karl
authors: K
authors: Schaller
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography / Q000379:methods*; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D002941:Circle of Willis / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000473:pathology*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009038:Motion; D014057:Tomography, X-Ray Computed