title: Gefitinib trial in a fanconi's anemia patient with multiple squamous cell carcinomas and hepatocellular carcinoma.
abstract: FA (Fanconi's Anemia) is an autosomal recessive disorder that is characterized by pancytopenia with bone marrow hypoplasia, diverse congenital abnormalities and an increased predisposition towards malignancy. The mainstay of the treatment for these cancers has been surgery, because of the hypersensitive reactions of FA patients to DNA cross- linking agents or radiation. Therefore, there has been no effective therapy for advanced squamous cell carcinoma. We report here on a patient suffering from advanced multiple squamous cell carcinoma and hepatocellular carcinoma along with an FA, and this patient was treated with gefitinib.
authors: Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
authors: Hae Sun
authors: HS
authors: Jung
authors: Gun-Woo
authors: GW
authors: Byun
authors: Kyoung-Eun
authors: KE
authors: Lee
authors: Yeung Chul
authors: YC
authors: Mun
authors: Seung Hyun
authors: SH
authors: Nam
authors: Jung Mi
authors: JM
authors: Kwon
authors: Shi Nae
authors: SN
authors: Lee
authors: Seock-Ah
authors: SA
authors: Im
authors: Chu-Myong
authors: CM
authors: Seong
authors: Soon Nam
authors: SN
authors: Lee