[Research and application of cell transplantation in the treatment of diabetes mellitus: a review].
In the conventional treatments of type I diabetes, there are various problems. As a new adequate treatment of diabetes, cell replacement therapy of diabetes has been applied and given research priority. We have investigated the applications of cell transplantation in the treatment of diabetes and have retrieved the relevant articles on cells transplantation for the treatment of diabetes. In this paper, we review the history, development, merits and demerits of cell transplantation and the recent advances in pancreatic islet transplantation research. The latest progress in the induction of stem cell to differentiate into the insulin-producing cells was also introduced.
Wei
Lingling
L
Key Laboratory of Transplant Engineering and Immunology, Ministry of Health, West China Hospital, Sichuan University, Chengdu 610041, China.
Lu
Yanrong
Y
Cheng
Jingqiu
J
D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery* / Q000628:therapy; D006801:Humans; D050417:Insulin-Secreting Cells / Q000166:cytology*; D016381:Islets of Langerhans Transplantation / Q000379:methods; D033581:Stem Cell Transplantation