[Adverse reactions during fluorescence fundus angiography in special patients].
OBJECTIVE
To determine the incidence rate and correlation factors of the adverse reactions during fluorescence fundus angiography (FFA) in special patients.


METHODS
256 special patients were performed FFA with Heidelberg Retinal Angiography. Fluorescein Sodium was given according to the body weight and adverse reactions during FFA were observed. The special patients enrolled in this study include those with drug allergy history, system disease, light adverse reactions such as nausea, vomiting and pruritus during the fist FFA or patients over 80 years old.


RESULTS
Adverse reactions were observed in 69 of 256 (27.0%) cases and the majority is at a mild to moderate degree. Nausea, sneezing, vomiting or pruritus occurred in 10 of 73 (13.7%) patients with drug allergy history. Nausea or vomiting occurred in 4 of 78 (5.1%) patients with systemic diseases. Different degrees of adverse reactions occurred in 54 of 56 (94.6%) cases who had nausea, vomiting or pruritus during the first FFA. Nausea occurred in 1 of 49 (2.0%) patients over 80 years old.


CONCLUSIONS
FFA is a safe examination for the above special patients. The incidence rate of adverse reaction due to FFA in these special patients is similar to that in the healthy population. Observing the patients closely and strengthening the containment and salvage measures are important to improve the safety of FFA in these special patients.
Su
Zhao-an
ZA
Eye Center of Affiliated Second Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China. zhaoansu@163.com
Zhang
Li-xia
LX
Teng
Yan
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D019793:Fluorescein / Q000009:adverse effects; D005451:Fluorescein Angiography / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
D019793:Fluorescein