title: [Epidemiological characteristic of first case of locally identified A/H1N1 secondary cases caused by imported source of infection in China].
abstract: OBJECTIVE
  To study the first locally identifed A/H1N1 secondary cases outbreak in China.
  
  
  METHODS
  Interview and field investigation were integrated to describe the whole process of transmission on each case and to illustrate the relationships between the onset of the disease and the retated factors.
  
  
  RESULTS
  Two contact persons appearanced fever and whose throat swabs were tested positive to H1N1 viral nucleic acid. The two had a history of contact in a short distance with the initial imported case without any protective measure in the poor air ventilation. The patients clinical situation was slight. The incubation was between 37 hours and 57 hours. No other new case was found after intervention as isolation and antisepsis were taken.
  
  
  CONCLUSIONS
  This event was proved to be an outbreak of local A/H1N1 secondary cases caused by the imported case. The main mode of transmission was personal contact in a short distance without protection, through air and droplet. The locus with poor air ventilation was high risk place. Contact persons should be observed seven days and tested continuously. Infectivity and pathogenicity of the A/H1N1 virus were limited and appeared weakened by generations. Patient's condition was related with persistence and frequency of contact with the infection sources. Enhancing management of contact persons, health education, early diagnose, early treatment and early insulation were effective measures of controling and prenventing the spread A/H1N1.
authors: Guangzhou Center for Disease Control and Prevention, Guangzhou, China.
authors: Zhi-Cong
authors: ZC
authors: Yang
authors: Tie-Gang
authors: TG
authors: Li
authors: Yu-Fei
authors: YF
authors: Liu
authors: Xin-Wei
authors: XW
authors: Wu
authors: Jun
authors: J
authors: Yuan
authors: Chao-Jun
authors: CJ
authors: Xie
authors: Kui-Biao
authors: KB
authors: Li
authors: Li-Yun
authors: LY
authors: Jiang
authors: Yi-Yun
authors: YY
authors: Chen
authors: Xin-Wu
authors: XW
authors: Mao
authors: Hai-Lin
authors: HL
authors: Li
authors: Liu-Hua
authors: LH
authors: Zhan
authors: Xiao-Ling
authors: XL
authors: Xiao
authors: Jian-Ping
authors: JP
authors: Liu
authors: Ji-Chuan
authors: JC
authors: Shen
authors: Wen-Feng
authors: WF
authors: Cai
authors: Ming
authors: M
authors: Wang
mesh_terms: D002681:China / Q000453:epidemiology; D016358:Contact Tracing; D004196:Disease Outbreaks; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D007407:Interviews as Topic; D010356:Patient Isolation