Primary malignant non-Hodgkin's lymphomas of salivary glands.
We evaluated the medical record of patients with salivary gland neoplasms diagnosed at Timisoara City Hospital from 2002 to 2009. A study has been carried out for seven years on 204 cases of salivary gland tumors and only two cases of salivary gland lymphomas were diagnosed. The two cases were females of 71- and 49-year-old, respectively. The formalin-fixed paraffin-embedded tissue samples were cut in 4 mum thick sections and stained with Hematoxylin and Eosin. The primary monoclonal antibodies for the immunohistochemical analysis were the followings: LCA (2B11, Dako), CD20 (L26, Dako), cytokeratin (MNF116, Dako), p53 (DQ-7, Dako), and PCNA (PC-10, Dako). The histopathology and immunohistochemistry suggested in the first case a low-grade diffuse large B-cell mucosa associated lymphoid tissue lymphoma and in the second case a high-grade extranodal marginal zone B-cell lymphoma.
Faur
Alexandra
A
Department of Pathology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania. alexandra_pantu@yahoo.co
Lazăr
Elena
E
Cornianu
Mărioara
M
Dema
Alis
A
Lăzureanu
Codruţa
C
Mureşan
Anca
A
Tăban
Sorina
S
D000368:Aged; D018951:Antigens, CD20 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology*; D008875:Middle Aged; D011379:Prognosis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012383:Romania; D012468:Salivary Gland Neoplasms / Q000401:mortality / Q000473:pathology*; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D018809:Proliferating Cell Nuclear Antigen; D016159:Tumor Suppressor Protein p53; D007633:Keratins