title: [Current views on the pathogenesis of depression and approaches to antidepressive therapy (in case of coaxil)].
abstract: The review considers the current theories of depression and its clinical manifestations, as well as the factors that determine the likelihood of depression. It presents information on cerebral structural and functional changes observed in depression. There are data on the tactics of antidepressive therapy as a whole and on the use of coaxil in particular.
authors: N A
authors: NA
authors: Tiuvina
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001921:Brain / Q000378:metabolism; D002490:Central Nervous System / Q000503:physiopathology; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology* / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology; D020022:Genetic Predisposition to Disease; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D013841:Thiazepines / Q000627:therapeutic use*
chemical_list: D000700:Analgesics; D000929:Antidepressive Agents, Tricyclic; D013841:Thiazepines; C050504:tianeptine