[C-reactive protein, risk of and survival after cancer--secondary publication].
10,408 individuals from the general Danish population who had CRP measured at baseline were followed for up to 16 years; 1,624 developed cancer and among these, 998 died during follow-up. Multifactorially adjusted hazard ratios for the highest versus the lowest quintile of CRP were 1.3 (95% confidence interval, 1.0-1.6) for cancer of any type, 2.1 (1.2-3.8) for lung cancer, 1.7 (0.8-3.2) for colorectal cancer, and 0.9 (0.5-1.7) for breast cancer. Multifactorially adjusted hazard ratios for early death in patients with cancer were 1.8 (1.2-2.7) for CRP > 3 versus < 1 mg/L.
Allin
Kristine H
KH
Herlev Hospital, Klinisk Biokemisk Afdeling, Herlev, Denmark.
Bojesen
Stig E
SE
Nordestgaard
Børge G
BG
D014408:Biomarkers, Tumor / Q000097:blood*; D002097:C-Reactive Protein / Q000032:analysis*; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000097:blood / Q000401:mortality; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000401:mortality; D008297:Male; D009369:Neoplasms / Q000097:blood* / Q000401:mortality; D011446:Prospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D015996:Survival Rate
D014408:Biomarkers, Tumor; D002097:C-Reactive Protein