Purpura fulminans as the presenting manifestation in a patient with juvenile SLE.
We present a 12-year-old girl with systemic lupus erythematosus and associated antiphospholipid syndrome who developed an unusual manifestation of purpura fulminans in an accelerated fashion. The patient improved after prompt treatment with anticoagulants, aggressive immunosuppressive drugs and plasmapheresis. This is the first pediatric case of purpura fulminans due to secondary antiphospholipid syndrome of systemic lupus erythematosus. We suggest that SLE patients with lupus anticoagulant should be followed closely for similar complications.
Demirkaya
Erkan
E
Units of Pediatric Rheumatology and Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Cakmakli
Hasan Fatih
HF
Güçer
Safak
S
Aktay-Ayaz
Nuray
N
Gürgey
Aytemiz
A
Ozen
Seza
S
D000925:Anticoagulants / Q000008:administration & dosage; D016736:Antiphospholipid Syndrome / Q000150:complications; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D010956:Plasmapheresis; D055665:Purpura Fulminans / Q000188:drug therapy / Q000209:etiology*
D000925:Anticoagulants; D007166:Immunosuppressive Agents