title: Angioleiomyomas in the bilateral broad ligaments.
abstract: The female genital tract is a rare site for angioleiomyoma. Here, we present an unusual case of bilateral large angioleiomyoma in the broad ligaments. A 52-year-old woman underwent total hysterectomy with bilateral salpingo-oophorectomy due to massive tumors in the bilateral adnexal regions. Gross examination revealed a hemangioma-like mass each in the bilateral broad ligaments. The right one extended into the uterine myometrium. Histologically, both tumors had a mixed pattern of prominent thick-walled blood vessels and cellular short spindle myoid cells throughout. The spindle cells often swirled around the vessels, displaying an overlapping feature with angiomyofibroblastoma or myopericytoma. Immunostaining demonstrated that the tumor cells were positive for alpha-smooth muscle actin, desmin, estrogen receptor, and progesterone receptor. We believe that angioleiomyoma should be recognized as a delineated variant of leiomyoma in the female genital tract. This rare benign tumor should be differentiated from other mesenchymal neoplasms with prominent blood vessels.
authors: Department of Pathology, The Affiliated Women's Hospital, School of Medicine, Zhejiang University, Zhejiang Province, PR China.
authors: Xiaoduan
authors: X
authors: Chen
authors: Xiaofei
authors: X
authors: Zhang
authors: Suojiang
authors: S
authors: Zhang
authors: Bingjian
authors: B
authors: Lü
mesh_terms: D018229:Angiomyoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D001956:Broad Ligament / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D007044:Hysterectomy; D007150:Immunohistochemistry; D033162:Incidental Findings; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery