Reactogenicity and immunogenicity of combined Haemophilus influenzae type b-meningococcal serogroup C conjugate vaccine booster dose coadministered with measles, mumps, and rubella vaccine.
A booster dose of Haemophilus influenzae type b-Neisseria meningitidis serogroup C conjugate (Hib-MenC-TT) vaccine simultaneously administered with measles, mumps, and rubella (MMR) vaccine in 13- to 14-month-old Spanish toddlers, primed with 3 doses of a combined Diphteria-Tetanus-Acellular Pertusis DTPa-Hib-containing vaccine and a MenC-CRM197 conjugate vaccine, had a good reactogenicity profile and induced similar Hib and MenC booster responses and MMR seropositivity rates as the vaccines given alone.
Carmona
Alfonso
A
Instituto Hispalense de Pediatría, Sevilla, Spain.
Miranda
Mariano
M
Barrio
Francisco
F
De Vicente
Ana
A
Mares
Josep
J
Muñoz
Eulalia
E
Diez-Delgado
Javier
J
Alonso
Angeles
A
Giménez-Sánchez
Francisco
F
Merino
José
J
García-Corbeira
Pilar
P
Maechler
Gudrun
G
Boutriau
Dominique
D
D000907:Antibodies, Bacterial / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D018073:Haemophilus Vaccines / Q000009:adverse effects* / Q000276:immunology*; D006801:Humans; D007117:Immunization, Secondary / Q000009:adverse effects* / Q000379:methods; D007223:Infant; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000009:adverse effects* / Q000276:immunology*; D022401:Meningococcal Vaccines / Q000009:adverse effects* / Q000276:immunology*; D013030:Spain; D013745:Tetanus Toxoid / Q000009:adverse effects* / Q000276:immunology*; D017778:Vaccines, Combined / Q000009:adverse effects / Q000276:immunology
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral; D018073:Haemophilus Vaccines; C055753:Haemophilus influenza type b polysaccharide vaccine-tetanus toxin conjugate; D022542:Measles-Mumps-Rubella Vaccine; D022401:Meningococcal Vaccines; D013745:Tetanus Toxoid; D017778:Vaccines, Combined; C410218:serogroup C meningococcal conjugate vaccine