title: Two new cytotoxic acetophenone derivatives from Euphorbia ebracteolata Hayata.
abstract: Two new acetophenone derivatives were isolated from the roots of Euphorbia ebracteolata Hayata, their structures were elucidated as 2,4-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone (1) and 2-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone-4-O-beta-D-glucopyranoside (2) on the basis of chemical and spectroscopic methods including (1)D- and (2)D-NMR techniques, and their cytotoxic activities were investigated by using the MTT method.
authors: Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, PR China.
authors: Ning
authors: N
authors: Zhang
authors: Hao
authors: H
authors: Cai
authors: BaoChang
authors: B
authors: Cai
authors: HaiJun
authors: H
authors: Yang
authors: JunSong
authors: J
authors: Li
authors: GuangMing
authors: G
authors: Yang
mesh_terms: D000098:Acetophenones / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D028481:Euphorbia / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D009005:Monosaccharides / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D018517:Plant Roots
chemical_list: C554153:2,4-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone; C554154:2-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone-4-O-beta-D-glucopyranoside; D000098:Acetophenones; D000972:Antineoplastic Agents, Phytogenic; D009005:Monosaccharides; D010936:Plant Extracts