title: Effect of parental overweight and serum leptin levels on the manifestation of overweight in 7-year-old Korean children.
abstract: OBJECTIVE
  To explore the relationship between children and their parents in terms of various anthropometric parameters and obesity-related hormone levels and to identify early indicators for child obesity.
  
  
  METHODS
  Cross-sectional observational study.
  
  
  METHODS
  Urban areas of Korea in 2005.
  
  
  METHODS
  A total 124 families with 7-year-old children participated. Anthropometric and blood biochemistry data and information concerning the children's lifestyles, dietary habits and parental and grandparental weight status were obtained.
  
  
  RESULTS
  The mean values for all anthropometric parameters were greater in overweight children than in children of normal weight. Very close relationships existed between the anthropometric parameters of children and their parents. Children with two overweight parents showed the highest odds for being overweight (OR 7.62). The strong relationship between overweight children and grandparental and parental overweight, especially on the maternal side, suggests gender differences in the intergenerational transmission of body weight. We also noted a greater risk of being overweight in children with a parent with high serum leptin level.
  
  
  CONCLUSIONS
  Grandparental and parental weight status and parental serum leptin levels enable us to identify childhood obesity at an early age and may help to counter the current epidemic of adult obesity.
authors: Division of Metabolic Diseases, Center for Biomedical Sciences, National Institute of Health, 194 Tongillo, Eunpyeong-ug, Seoul 122-701, Korea.
authors: In K
authors: IK
authors: Kim
authors: Hye-Ja
authors: HJ
authors: Lee
authors: Jae H
authors: JH
authors: Kang
authors: Jihyun
authors: J
authors: Song
mesh_terms: D000328:Adult; D019540:Area Under Curve; D015992:Body Mass Index; D002648:Child; D003430:Cross-Sectional Studies; D005191:Family Characteristics; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D016901:Intergenerational Relations; D007723:Korea; D020738:Leptin / Q000097:blood*; D008019:Life Style; D008297:Male; D050177:Overweight / Q000097:blood* / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics; D010287:Parent-Child Relations; D015995:Prevalence; D012372:ROC Curve; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D020738:Leptin