[Ishemic-reperfusion syndrome prophylaxis in general hypothermia in experiment].
The influence of general supercooling on rats were studied. The action of corvitin and pentoxiphillin on the prooxidant-antioxidant homeostasis for conditions of general supercooling were analysed. On the based of investigations results analysis of lipids peroxide oxidation indexes and antioxidant protection system in animals it were established, that corvitin in difference of pentoxiphillin give more significant protectory effect in conditions of ishemic-reperfusion syndrome.
Zubkov
V I
VI
Khytryĭ
H P
HP
Luk'ianchuk
V D
VD
Shalamaĭ
A S
AS
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D001831:Body Temperature; D002374:Catalase / Q000378:metabolism; D005260:Female; D005947:Glucose / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D006706:Homeostasis / Q000187:drug effects*; D007035:Hypothermia / Q000150:complications* / Q000201:enzymology / Q000378:metabolism; D019344:Lactic Acid / Q000378:metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D019289:Pyruvic Acid / Q000378:metabolism; D011794:Quercetin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D051381:Rats; D015427:Reperfusion Injury / Q000201:enzymology / Q000378:metabolism / Q000517:prevention & control*; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D016896:Treatment Outcome
D000975:Antioxidants; D008054:Lipid Peroxides; D013438:Sulfhydryl Compounds; D017392:Thiobarbituric Acid Reactive Substances; D019344:Lactic Acid; D019289:Pyruvic Acid; D011794:Quercetin; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione; D005947:Glucose