Infrequent replication of parvovirus B19 and erythrovirus genotypes 2 and 3 among HIV-infected patients with chronic anemia.
We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients.
Ferry
Tristan
T
Geneva University Hospital, Geneva, Switzerland. tristan.ferry@univ-lyon1.f
Hirschel
Bernard
B
Dang
Thanh
T
Meylan
Pascal
P
Delhumeau
Cécile
C
Rauch
Andri
A
Weber
Rainer
R
Elzi
Luigia
L
Bernasconi
Enos
E
Schmid
Patrick
P
Calmy
Alexandra
A
D000328:Adult; D000740:Anemia / Q000097:blood / Q000150:complications / Q000821:virology*; D002908:Chronic Disease; D015331:Cohort Studies; D004279:DNA, Viral / Q000097:blood; D019218:Erythrovirus / Q000302:isolation & purification / Q000502:physiology*; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000150:complications / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000097:blood / Q000150:complications / Q000821:virology; D016732:Parvovirus B19, Human / Q000302:isolation & purification / Q000502:physiology*; D016133:Polymerase Chain Reaction; D014779:Virus Replication
D004279:DNA, Viral