title: Oral manifestations in the epidermolysis bullosa spectrum.
abstract: The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mutations for these disorders. In this article, the major oral manifestations are reviewed for different EB subtypes and are related to the causative genetic mutations and gene expression.
authors: Department of Pediatric Dentistry, School of Dentistry, Brauer Hall # 7450, The University of North Carolina, Chapel Hill, NC 27599-7450, USA. tim_wright@dentistry.unc.edu
authors: J Timothy
authors: JT
authors: Wright
mesh_terms: D004820:Epidermolysis Bullosa / Q000150:complications* / Q000473:pathology; D006801:Humans; D009059:Mouth Diseases / Q000209:etiology* / Q000473:pathology; D014076:Tooth Diseases / Q000209:etiology* / Q000473:pathology