title: An implantable bi-directional brain-machine interface system for chronic neuroprosthesis research.
abstract: An implantable bi-directional brain-machine interface (BMI) prototype is presented. With sensing, algorithm, wireless telemetry, and stimulation therapy capabilities, the system is designed for chronic studies exploring closed-loop and diagnostic opportunities for neuroprosthetics. In particular, we hope to enable fundamental chronic research into the physiology of neurological disorders, define key electrical biomarkers related to disease, and apply this learning to patient-specific algorithms for therapeutic stimulation and diagnostics. The ultimate goal is to provide practical neuroprosthetics with adaptive therapy for improved efficiency and efficacy.
authors: Medtronic Neuromodulation Technology, Minneapolis, MN 55432.
authors: Scott
authors: S
authors: Stanslaski
authors: Peng
authors: P
authors: Cong
authors: Dave
authors: D
authors: Carlson
authors: Wes
authors: W
authors: Santa
authors: Randy
authors: R
authors: Jensen
authors: Greg
authors: G
authors: Molnar
authors: William J
authors: WJ
authors: Marks
authors: Afsah
authors: A
authors: Shafquat
authors: Tim
authors: T
authors: Denison
mesh_terms: D035843:Biomedical Research / Q000295:instrumentation; D001921:Brain / Q000503:physiopathology*; D002908:Chronic Disease; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D009422:Nervous System Diseases / Q000175:diagnosis / Q000534:rehabilitation*; D019736:Prostheses and Implants; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D013686:Telemetry / Q000295:instrumentation*; D013813:Therapy, Computer-Assisted / Q000295:instrumentation; D014584:User-Computer Interface