[Some indices of lipids metabolism and antioxidant profile in geriatric patients with arterial hypertension].
Arterial hypertension contributes essentially into development of chronic heart failure and chronic ischemia of the brain, which results in social dependence of geriatric patients. One of the important factors in the development of arterial hypertension is the state of lipids peroxidation. Misbalance among the products of lipids peroxidation and components of antioxidation defense system revealed in cardiovascular diseases (mainly in arterial hypertension and heart failure) promotes progress of these diseases and premature aging of an organism. The therapy aimed at normalization of the oxidative profile of the patients with arterial hypertension should include prolonged beta-blockers, ACE inhibitors, calcium antagonists, statines and polyvitamin complexes with vitamins A and E.
Kharitonova
T V
TV
Kozina
L S
LS
Zakharchuk
A G
AG
D000368:Aged; D000375:Aging / Q000378:metabolism*; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000201:enzymology / Q000378:metabolism*; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008875:Middle Aged; D010084:Oxidation-Reduction; D012720:Severity of Illness Index; D013438:Sulfhydryl Compounds / Q000378:metabolism
D000975:Antioxidants; D015415:Biomarkers; D013438:Sulfhydryl Compounds; D008315:Malondialdehyde