title: Association of porcine IGF binding protein-5 gene with meat quality.
abstract: IGFBP-5 is a member of the IGF families. Using PCR-SSCP, genotypic and allelic frequencies were analyzed in 18 pig breeds (n = 600). The association between haplotypes and production performance was analyzed in a Jinhua x Pietrain population family (n = 212, total 24 traits). Two SNPs (T199C and G485A) within the gene were analyzed. The breeds had different genotypic and allelic frequencies. Typically, the Chinese native pig breeds carried a higher allele C and G frequency (over 50%) than those of the European pigs, and only Guangdong Large White and wild boar were at Hardy-Weinberg equilibrium. The pigs carrying the CG haplotype had higher hue, loin, and thigh pH1 values than pigs with the TA haplotype, and pigs with the TA haplotype had the lowest loin pH2 value and highest color-a value among the haplotypes. It is proposed that the IGFBP-5 gene is associated with the variation in meat quality, especially in pH value together with other QTLs on chromosome 15.
authors: College of Food Science and Engineering, Jiangxi Agricultural University, Nanchang 330045, China. wwjun9999@sina.com
authors: Wenjun
authors: W
authors: Wang
authors: Kehui
authors: K
authors: Ouyang
authors: Xinchen
authors: X
authors: Shangguan
authors: Mingsheng
authors: M
authors: Xu
mesh_terms: D050154:Adiposity / Q000235:genetics / Q000502:physiology; D000818:Animals; D001824:Body Constitution / Q000235:genetics; D050218:Body Fat Distribution; D001835:Body Weight / Q000235:genetics; D002875:Chromosomes; D003001:Cloning, Molecular; D005787:Gene Frequency; D008040:Genetic Linkage; D005838:Genotype; D006863:Hydrogen-Ion Concentration; D018975:Insulin-Like Growth Factor Binding Protein 5 / Q000235:genetics* / Q000502:physiology; D008460:Meat / Q000032:analysis; D020641:Polymorphism, Single Nucleotide; D011786:Quality Control; D040641:Quantitative Trait Loci / Q000235:genetics; D013552:Swine / Q000033:anatomy & histology / Q000235:genetics*
chemical_list: D018975:Insulin-Like Growth Factor Binding Protein 5