title: CE-MALDI interface based on inkjet technology.
abstract: An ink jet printer valve and a nozzle were used to deliver matrix and sample from an electrophoresis capillary onto a MALDI plate. The system was evaluated by the separation of a set of standard peptides. That separation generated up to 40 000 theoretical plates in less than 3 min. Detection limits were 500 amol for an ABI TOF-TOF instrument and 2 fmol for an ABI Q-TOF instrument. Over 70% coverage was obtained for the tryptic digest of alpha-lactalbumin in less than 2.5 min.
authors: Department of Chemistry, University of Washington, Seattle, WA, USA.
authors: Michael W
authors: MW
authors: Vannatta
authors: Colin D
authors: CD
authors: Whitmore
authors: Norman J
authors: NJ
authors: Dovichi
mesh_terms: D000804:Angiotensin II / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000295:instrumentation*; D004867:Equipment Design; D010455:Peptides / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000295:instrumentation*
chemical_list: D010455:Peptides; D000804:Angiotensin II