title: Hemostatic changes in patients with end stage renal disease undergoing hemodialysis.
abstract: Patients undergoing hemodialysis may show both thrombotic complications and bleeding abnormalities. Hemostatic changes in patients on hemodialysis may result from alterations in vessel wall integrity and platelet function, and reduced blood flow in the native arteriovenous fistula. Vascular complications represent 20-25% of all hospitalizations of patients on hemodialysis. Literature survey revealed that changes in the hemostatic system may play a major role in vascular complications observed in these patients. Thus, it is essential to investigate hemostatic alterations in patients on hemodialysis so that adequate regimes for anticoagulant therapy could be implemented. In this review we discuss hemostatic abnormalities in end stage renal disease patients undergoing hemodialysis.
authors: Clinical and Toxicological Analysis Department - Faculty of Pharmacy, Federal University of Minas Gerais, Brazil.
authors: Danyelle Romana Alves
authors: DR
authors: Rios
authors: Maria das Graças
authors: Md
authors: Carvalho
authors: Bashir A
authors: BA
authors: Lwaleed
authors: Ana Cristina
authors: AC
authors: Simões e Silva
authors: Karina Braga Gomes
authors: KB
authors: Borges
authors: Luci Maria Santana
authors: LM
authors: Dusse
mesh_terms: D001775:Blood Circulation; D001792:Blood Platelets / Q000502:physiology; D005342:Fibrinolysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy*; D006435:Renal Dialysis / Q000009:adverse effects*