title: [A case of eosinophilic cystitis that was treated with oral suplatast tosilate (IPD-1151T)].
abstract: A 51-year-old woman with a chief complaint of micturition pain and sensation of incomplete voiding was suspected of suffering from a bladder tumor, according to the findings of cystoscopy and ultrasonography. Transurethral punch biopsy of the submucosa of the bladder wall revealed eosinophilic infiltration without malignancy. Conservative treatment with corticosteroids resulted in excellent relief of symptoms and objective remission of the bladder lesions. However, her symptoms recurred 11 weeks after finishing the treatment. She was then treated with a combination of corticosteroid and suplatast tosilate, followed by monotherapy with suplatast tosilate. The treatment was effective for the improvement of symptoms, and serum immunoglobulin E and blood eosinophil levels were reduced. No disease progression was noted after the treatment with suplatast tosilate. To our knowledge, this is the first case of eosinophilic cystitis treated with suplatast tosilate.
authors: The Department of Urology, Dokkyo University School of Medicine, Japan.
authors: Miho
authors: M
authors: Watanabe
authors: Keiichi
authors: K
authors: Yamaguchi
authors: Tomonori
authors: T
authors: Yamanishi
authors: Takao
authors: T
authors: Kamai
authors: Ken-Ichiro
authors: K
authors: Yoshida
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D018926:Anti-Allergic Agents / Q000008:administration & dosage*; D001190:Arylsulfonates / Q000008:administration & dosage*; D003556:Cystitis / Q000188:drug therapy*; D004802:Eosinophilia / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013452:Sulfonium Compounds / Q000008:administration & dosage*
chemical_list: D000305:Adrenal Cortex Hormones; D018926:Anti-Allergic Agents; D001190:Arylsulfonates; D013452:Sulfonium Compounds; C073028:suplatast tosilate