[Progress in researches on the molecular genetics of developmental dysplasia of the hip].
Epidemiological studies have confirmed that genetic factors play an important role in the incidence of developmental dysplasia of the hip (DDH). Previous studies showed that genetic factors accounted for a major part (about 67.88%), the remaining part was due to the environmental factors. At present, great progress has been made in the researches of the diagnosis and treatment of DDH, but there is no clear conclusion in the genetic etiology. This article reviews the latest studies of candidate genes and their mapping.
Fan
Jianbo
J
The Center for Diagnosis and Treatment of Joint Disease, Drum Tower Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210008 PR China.
Shi
Dongquan
D
Jiang
Qing
Q
D005260:Female; D006618:Hip Dislocation, Congenital / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D006801:Humans; D008297:Male; D010375:Pedigree