title: RETRACTED: miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the editors. This article was published on December 8, 2009. In November 2021, The Ohio State University notified the Cancer Cell editors that this article contains ten instances of plagiarized text; that Figures 1G, 5B, 5E, 7D, and 7F were falsified; and that part of Figure 1G in the article is the same as part of Figure 1B in another article that was later retracted (Garofalo et al., 2008, PLOS One 3, e4070, https://doi.org/10.1371/journal.pone.0004070). The university recommended the editors correct or retract the article. Given the extent and severity of these issues, the editors are retracting the article. S.-S. S. agrees with the retraction, and M.G., G.D.L., G.N., F.P., P.S., P.G., G.C., and C.M.C. disagree with the retraction; all other authors couldn't be reached or didn't respond.
authors: Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
authors: Michela
authors: M
authors: Garofalo
authors: Gianpiero
authors: G
authors: Di Leva
authors: Giulia
authors: G
authors: Romano
authors: Gerard
authors: G
authors: Nuovo
authors: Sung-Suk
authors: SS
authors: Suh
authors: Apollinaire
authors: A
authors: Ngankeu
authors: Cristian
authors: C
authors: Taccioli
authors: Flavia
authors: F
authors: Pichiorri
authors: Hansjuerg
authors: H
authors: Alder
authors: Paola
authors: P
authors: Secchiero
authors: Pierluigi
authors: P
authors: Gasparini
authors: Arianna
authors: A
authors: Gonelli
authors: Stefan
authors: S
authors: Costinean
authors: Mario
authors: M
authors: Acunzo
authors: Gerolama
authors: G
authors: Condorelli
authors: Carlo Maria
authors: CM
authors: Croce
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology; D015536:Down-Regulation / Q000502:physiology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D035683:MicroRNAs / Q000502:physiology*; D051059:PTEN Phosphohydrolase / Q000502:physiology*; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000502:physiology*; D019717:Tissue Inhibitor of Metalloproteinase-3 / Q000502:physiology*
chemical_list: D035683:MicroRNAs; D051059:PTEN Phosphohydrolase; D053221:TNF-Related Apoptosis-Inducing Ligand; D019717:Tissue Inhibitor of Metalloproteinase-3; C525709:MIR221, human; C525710:MIR222, human; C088390:TIMP3 protein, human; C505653:TNFSF10 protein, human; C494929:PTEN protein, human