Exercise-induced functional mitral regurgitation in heart failure and preserved ejection fraction: a new entity.
We report here the worsening of functional mitral regurgitation (MR) during dynamic exercise Doppler echocardiography in four female patients with heart failure and preserved ejection fraction. MR worsened concomitantly to an increase in systolic mitral tenting area and in E/E(a) ratio, whereas local left ventricular (LV) remodelling was not substantially aggravated by exercise. We accordingly suggest that exercise-induced increase in LV filling or left atrial pressure that in turn leads to increase in mitral tenting area worsens functional MR during exercise.
Maréchaux
Sylvestre
S
Centre Hospitalier Régional et Universitaire de Lille, Service d'explorations fonctionnelles cardiovasculaires, Lille, France.
Terrade
Julia
J
Biausque
Frédéric
F
Lefetz
Yann
Y
Deturck
Régis
R
Asseman
Philippe
P
Le Jemtel
Thierry H
TH
Ennezat
Pierre V
PV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015150:Echocardiography, Doppler; D015444:Exercise; D017079:Exercise Tolerance; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D013318:Stroke Volume