title: Herpes simplex virus type-1 pneumonitis in immunocompetent young woman.
abstract: A healthy young woman presented with an overwhelming hyperacute herpes simplex virus-1 pneumonia that dramatically responded to intravenous acyclovir. It is postulated that the infection was a reactivation of latent virus in the vagal ganglia, in the absence of retrograde extension of herpes labialis/gingivostomatitis, or hematogenous spread from extragenital and other sources of infection. It is also postulated that the patient's amazing improvement overnight was a real-time coincidence of spontaneous recovery from the viral infection and prompt initiation of acyclovir treatment.
authors: Department of Clinical Laboratories, Morris Hospital, Morris, Illinois, USA.
authors: Cesar V
authors: CV
authors: Reyes
authors: John R
authors: JR
authors: Bolden
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D001999:Bronchoscopy; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D006801:Humans; D011014:Pneumonia / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy / Q000821:virology; D013183:Sputum / Q000166:cytology; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir