[Cutaneous lymphomas].
Cutaneous lymphomas are lymphoproliferations affecting skin only at the time of diagnosis. There are two major types, B-cell lymphomas and T-cell lymphomas, which prognosis depends of histological subtype and staging evaluation. In cutaneous B-cell lymphomas, there are two indolent subtypes (primary cutaneous marginal zone B-cell lymphoma and primary cutaneous follicle center lymphoma) and one more aggressive type (primary cutaneous diffuse large B-cell lymphoma, leg type). Classification of T-cell lymphomas distinguishes indolent subtypes such as mycosis fungoides, the most frequent of T-cell lymphomas, and CD30+ lymphoproliferations such as lymphomatoid papulosis, whereas other T-cell lymphoma subtypes have a more pejorative prognosis such as Sezary syndrome (erythrodermic and leukemic form of mycosis fungoides) and CD30- lymphomas. Staging evaluation with CT-scan of chest, abdomen and pelvis, bone marrow examination if necessary and lymph node biopsy if palpable node over 1 or 1.5 cm diameter, is necessary for therapeutic decision.
Ingen-Housz-Oro
Saskia
S
Service de dermatologie, CHU Henri-Mondor, AP-HP, 94000 Créteil, France. saskia.oro@hmn.aphp.fr
Bagot
Martine
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D016399:Lymphoma, T-Cell / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D009182:Mycosis Fungoides / Q000175:diagnosis / Q000000981:diagnostic imaging; D009367:Neoplasm Staging; D011379:Prognosis; D011860:Radiography, Abdominal; D013902:Radiography, Thoracic; D012751:Sezary Syndrome / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D014057:Tomography, X-Ray Computed