title: Evolution in health and medicine Sackler colloquium: Evolution and public health.
abstract: Evolution and its elements of natural selection, population migration, genetic drift, and founder effects have shaped the world in which we practice public health. Human cultures and technologies have modified life on this planet and have coevolved with myriad other species, including microorganisms; plant and animal sources of food; invertebrate vectors of disease; and intermediate hosts among birds, mammals, and nonhuman primates. Molecular mechanisms of differential resistance or susceptibility to infectious agents or diets have evolved and are being discovered with modern methods. Some of these evolutionary relations require a perspective of tens of thousands of years, whereas other changes are observable in real time. The implications and applications of evolutionary understanding are important to our current programs and policies for infectious disease surveillance, gene-environment interactions, and health disparities globally.
authors: Department of Internal Medicine, Medical School and School of Public Health, University of Michigan, Center for Computational Medicine and Bioinformatics, Ann Arbor, MI 48109-2218, USA. gomenn@umich.edu
authors: Gilbert S
authors: GS
authors: Omenn
mesh_terms: D005075:Biological Evolution; D057231:Climate Change; D003141:Communicable Diseases / Q000276:immunology; D003468:Cultural Evolution; D003920:Diabetes Mellitus / Q000235:genetics; D004032:Diet; D004198:Disease Susceptibility; D004352:Drug Resistance, Microbial; D006801:Humans; D007108:Immune Tolerance; D007787:Lactose Intolerance; D011634:Public Health; D012641:Selection, Genetic; D014612:Vaccines / Q000276:immunology
chemical_list: D014612:Vaccines