title: Neighborhood graph and learning discriminative distance functions for clinical decision support.
abstract: There are two essential reasons for the slow progress in the acceptance of clinical case retrieval and similarity search-based decision support systems; the especial complexity of clinical data making it difficult to define a meaningful and effective distance function on them and the lack of transparency and explanation ability in many existing clinical case retrieval decision support systems. In this paper, we try to address these two problems by introducing a novel technique for visualizing inter-patient similarity based on a node-link representation with neighborhood graphs and by considering two techniques for learning discriminative distance function that help to combine the power of strong "black box" learners with the transparency of case retrieval and nearest neighbor classification.
authors: Corporate Technology Division, Siemens AG, Erlangen, Germany. alexey.tsymbal@siemens.com
authors: Alexey
authors: A
authors: Tsymbal
authors: Shaohua Kevin
authors: SK
authors: Zhou
authors: Martin
authors: M
authors: Huber
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D020000:Decision Support Systems, Clinical; D003661:Decision Support Techniques; D016002:Discriminant Analysis