3-O-trans-caffeoylisomyricadiol: a new triterpenoid from Tamarix nilotica growing in Saudi Arabia.
A detailed chemical study of the aerial parts of Tamarix nilotica (Tamaricaceae) from Saudi Arabia led to the isolation of a new pentacyclic triterpenoid, 3-O-trans-caffeoylisomyricadiol, in addition to nine known compounds. The structures of all isolated compounds were unambiguously elucidated by 1D, 2D NMR, and mass spectrometry. In the radical scavenging (DPPH) assay, 3-O-trans-caffeoylisomyricadiol exhibited potent antioxidant activity with an IC50 value of 3.56 microM, while that for quercetin (standard antioxidant) was 5.72 microM.
Orfali
Raha S
RS
Pharmacognosy Department, School of Pharmacy, King Saud University, P.O. Box 90727, Riyadh 11623, Saudi Arabia.
Ebada
Sherif S
SS
El-Shafae
Azza M
AM
Al-Taweel
Areej M
AM
Lin
Wen H
WH
Wray
Victor
V
Proksch
Peter
P
D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D012529:Saudi Arabia; D032363:Tamaricaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C546047:3-O-trans-caffeoylisomyricadiol; D016166:Free Radical Scavengers; D014315:Triterpenes