Green tea consumption improves endothelial function but not circulating endothelial progenitor cells in patients with chronic renal failure.
This study was designed to determine the effect of green tea consumption in patients with chronic kidney disease (CKD) on flow-mediated endothelium-dependent vasodilation (FMD) and the number of circulating endothelial progenitor cells (EPCs). Forty patients with CKD requiring chronic dialysis were enrolled. The patients were divided into two groups: the catechin group that consumed green tea (5 g/day for 1 month) and the control group that consumed water. The number of EPCs, inflammatory markers, oxidative stress, and FMD were determined at baseline and 4 weeks after green tea consumption. Clinical characteristics, oxidative stress, inflammatory markers, and circulating EPCs number were not significantly different. FMD was significantly improved after 4 weeks in the catechin group (from 5.68±2.67% to 8.66±3.46%, p=0.002). Short-term green tea consumption induced a rapid improvement in FMD, but did not improve circulating EPC levels in patients with CKD.
Park
Chung Su
CS
Cardiovascular Center of Gwangju Veterans Hospital, Gwangju, Republic of Korea.
Kim
Weon
W
The Division of Cardiovascular of Internal Medicine, Kyung Hee University Medical Center, Seoul, Republic of Korea. Electronic address: mylovekw@hanmail.net.
Woo
Jong Shin
JS
The Division of Cardiovascular of Internal Medicine, Kyung Hee University Medical Center, Seoul, Republic of Korea.
Ha
Sang Jin
SJ
The Division of Cardiovascular of Internal Medicine, Kyung Hee University Medical Center, Seoul, Republic of Korea.
Kang
Won Yu
WY
Cardiovascular Center of Gwangju Veterans Hospital, Gwangju, Republic of Korea.
Hwang
Sun Ho
SH
Cardiovascular Center of Gwangju Veterans Hospital, Gwangju, Republic of Korea.
Park
Yong Wook
YW
Department of Rheumatology, Chonnam National University, Republic of Korea.
Kim
Yong Sook
YS
Heart Center, Chonnam National University, Republic of Korea.
Ahn
Young Keun
YK
Heart Center, Chonnam National University, Republic of Korea.
Jeong
Myung Ho
MH
Heart Center, Chonnam National University, Republic of Korea.
Kim
Wan
W
Cardiovascular Center of Gwangju Veterans Hospital, Gwangju, Republic of Korea.
D004730:Endothelium, Vascular / Q000473:pathology / Q000502:physiology*; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000178:diet therapy* / Q000473:pathology; D018384:Oxidative Stress / Q000502:physiology; D013234:Stem Cells / Q000473:pathology / Q000502:physiology*; D013662:Tea
D013662:Tea