[New strategies for fertility preservation in young women with cancer].
Especially young women with cancer face rising survival rates due to remarkable progress in oncologic therapies. Preserving fertility is a major concern for both patients and their next of kin. Well established reproductive technologies such as cryopreservation of fertilized oocytes after in vitro fertilization already make fertility preservation possible for some patients. This review is dedicated to the emerging techniques that are becoming widely accepted for fertility preservation in young women and girls with cancer, such as auto transplantation of ovarian tissue cryopreservation and in vitro maturation (IVM) of either oocytes or follicles. First results are encouraging. But some challenges still have to be tackled in order for these novel technologies to be routinely employed with the aim of successful fertility preservation.
Moffat
Rebecca
R
Abteilung für Gynäkologische Endokrinologie und Reproduktionsmedizin, Frauenspital, University of Basel, Switzerland.
De Geyter
Christian
C
von Wolff
Michael
M
D000293:Adolescent; D000328:Adult; D002648:Child; D015925:Cryopreservation / Q000639:trends; D004624:Embryo Transfer / Q000639:trends; D005260:Female; D005307:Fertilization in Vitro / Q000639:trends; D005544:Forecasting; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009369:Neoplasms / Q000503:physiopathology*; D010043:Outcome and Process Assessment, Health Care; D006080:Ovarian Follicle; D010053:Ovary; D010063:Ovum; D011247:Pregnancy; D012099:Reproductive Techniques / Q000639:trends*; D020554:Sperm Injections, Intracytoplasmic / Q000639:trends; D055815:Young Adult