Eosinophilic peritonitis in children on chronic peritoneal dialysis.
Eosinophilic peritonitis is a response of the peritoneum to foreign substances. It presents as cloudy dialysate and may be missed because not all laboratories report the eosinophil count, giving only the total number of polymorphonuclear cells. Over a 2-year period, eight children developed 13 episodes of eosinophilic peritonitis. Three episodes were asymptomatic other than cloudy fluid, five followed surgery and two were associated with gastroenteritis. Despite recurrent episodes, there were no adverse outcomes, although a raised peritoneal eosinophil count persisted in most cases. Eosinophilic peritonitis is under-diagnosed and may lead to unnecessary antibiotic therapy.
Quinlan
Catherine
C
Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK. QuinlC@gosh.nhs.uk
Cantwell
Michelle
M
Rees
Lesley
L
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001772:Blood Cell Count; D002097:C-Reactive Protein / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D008297:Male; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D012008:Recurrence
D000900:Anti-Bacterial Agents; D002097:C-Reactive Protein