A case of localized scleroderma in a sculptor and his wife.
The etiology of localized scleroderma is unknown, and its pathogenetic relationship to its systemic counterpart is unclear. Environmental exposures, notably to silica dust, have long been suspected in the pathogenesis of the disorder. However, its relationship to the localized variant has not been well described. Here we present 2 cases of localized scleroderma in a sculptor and his wife who have extensive exposure to silica dust.
Bakst
Richard
R
Department of Medicine, Mount Sinai Medical Center, New York, NY, USA.
Kovarik
Carrie
C
Werth
Victoria P
VP
D000368:Aged; D002516:Ceramics; D005260:Female; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D012594:Scleroderma, Localized / Q000139:chemically induced* / Q000473:pathology*; D012822:Silicon Dioxide / Q000009:adverse effects*; D018454:Spouses
D012822:Silicon Dioxide