title: Energy-based hemostatic devices in laparoscopic adrenalectomy.
abstract: OBJECTIVE
  In literature, few papers compare different hemostatic devices in laparoscopic adrenalectomy. This sequential cohort study analyzes the outcomes of laparoscopic adrenalectomy performed by different hemostatic instruments, to evaluate if any of them has any advantage over the other and as secondary endpoints, the impact of body mass index (BMI) and tumor size on the indication, and the outcome of laparoscopic adrenalectomy.
  
  
  METHODS
  Forty-six patients, aged 54.6 +/- 46 years, underwent laparoscopic adrenalectomy over 5 years. Mean BMI was 27 +/- 4.8 kg/m(2). Twenty-four patients had a left tumor, and 22 had a right one. Patients were divided into two groups according to the hemostatic device: Ultracision was used in 26 patients, and Ligasure was used in 20. Groups were well matched for histology, tumor size and site, BMI, gender, and age.
  
  
  RESULTS
  Mean operating time was 126.5 +/- 52 min, blood losses were 101 +/- 169 mm, conversion rate was 6.5%, morbidity was 26%, and hospitalization was 5.3 +/- 2.5 days. Groups did not differ for surgical time, blood losses, complications, and conversion rate; BMI and length of surgery were not related. Tumor side and size did not affect surgical time, regardless of the hemostatic tool. Patients submitted to left adrenalectomy bled more (p = 0.007) and had more complications (p = 0.016) than those undergone operation on the right side.
  
  
  CONCLUSIONS
  Obesity (BMI > 30) and large masses do not contraindicate laparoscopic adrenalectomy. Left adrenalectomies bleed more and have a higher morbidity. Hemostatic device choice is up to surgeon's preference.
authors: 1st Surgical Department, S. Gerardo Hospital, University of Milan Bicocca, Via Pergolesi 33, 20052, Monza, Italy. srtpvn@gmail.com
authors: Paola Vincenza
authors: PV
authors: Sartori
authors: Fabrizio
authors: F
authors: Romano
authors: Fabio
authors: F
authors: Uggeri
authors: Giovanni
authors: G
authors: Colombo
authors: Roberto
authors: R
authors: Caprotti
authors: Cristina
authors: C
authors: Giannattasio
authors: Mauro Alessandro
authors: MA
authors: Scotti
authors: Alberto
authors: A
authors: Delitala
authors: Massimo
authors: M
authors: Prada
authors: Franco
authors: F
authors: Uggeri
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000601:surgery; D000315:Adrenalectomy / Q000009:adverse effects / Q000295:instrumentation*; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016063:Blood Loss, Surgical / Q000517:prevention & control / Q000706:statistics & numerical data; D015992:Body Mass Index; D015331:Cohort Studies; D000075202:Contraindications; D005260:Female; D006489:Hemostatic Techniques / Q000295:instrumentation*; D006801:Humans; D007558:Italy; D010535:Laparoscopy / Q000009:adverse effects; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D014464:Ultrasonic Therapy / Q000295:instrumentation*