Preview. Stem cell transcriptional loops generate precise temporal identity.
Neuronal diversity is generated from small pools of progenitors whose fate potential changes over time. Recently in Cell, Baumgardt et al. (2009) showed that multiple, simultaneously activated transcriptional cascades regulate the timing and specification of distinct neurons from the lineage of a single embryonic Drosophila neural stem cell.
Kohwi
Minoree
M
Institute of Neuroscience, University of Oregon, Eugene, OR 97405, USA; Institute of Molecular Biology, University of Oregon, Eugene, OR 97405, USA; Howard Hughes Medical Institute, University of Oregon, Eugene, OR 97405, USA.
Doe
Chris Q
CQ