title: [Portal vein flow rate used as a early predictor of portal vein thrombosis after periesophagastric devascularization].
abstract: OBJECTIVE
  To evaluate the predictive value of portal vein flow rate preoperative for portal vein thrombosis (PVT) after periesophagastric devascularization in hepatitis B cirrhosis-related portal hypertension.
  
  
  METHODS
  From January 2007 to July 2008, 45 patients with portal hypertension caused by hepatitis B cirrhosis were performed splenectomy with peri-esophagogastric devascularization in the same medical group in West China Hospital of Sichuan University. The portal vein flow rate and the diameter of portal vein were measured with doppler sonography respectively before and after the operation. At the same time, the level of PT and PLT were detected. The weight of spleens were measured after operation.
  
  
  RESULTS
  Thirteen cases suffered from PVT postoperatively. Portal vein flow rate was significantly lower in patients with PVT postoperation than that in patients without PVT (P < 0.01). In patients with PVT (n = 13) postoperation, the preoperative portal vein flow rate was (19.5 +/- 5.3) cm/s. Among the 13 cases, there were 12 cases whose flow rate were lower than 25 cm/s, and 1 case whose flow rate was 32. 3 cm/s; In patients without PVT (n = 32), the preoperative portal vein flow rate was (9.6 +/- 8.0) cm/s. In patients with lower rate (n = 17), the incidence rate of PVT was 70.6%; in patients with higher rate (n = 28), the incidence rate of PVT was 3.6%. The incidence rate of PVT in patients with lower rate was significantly lower than patients with higher rate (P < 0.01). The diameter of portal vein in patients with PVT was significantly wider than patients without PVT. The diameter of portal vein was negative correlative with the portal vein flow rate. The value 25 cm/s was of diagnostic efficiency, the sensitivity was 92.3%, and specificity was 70.6%.
  
  
  CONCLUSIONS
  The portal vein flow rate preoperative can be used as an early predictor of portal vein thrombosis after periesophagastric devascularization in hepatitis B cirrhosis-related portal hypertension to give a guide to clinical work.
authors: Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Yu
authors: Y
authors: Zhang
authors: Tian-Fu
authors: TF
authors: Wen
authors: Zhe-Yu
authors: ZY
authors: Chen
authors: Lü-Nan
authors: LN
authors: Yan
authors: Guan-Lin
authors: GL
authors: Liang
authors: Guo
authors: G
authors: Li
authors: Xian-Hua
authors: XH
authors: Zhang
authors: Shun
authors: S
authors: Ran
authors: Zhi-Xua
authors: ZX
authors: Liao
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology; D011300:Preoperative Care; D012307:Risk Factors; D013156:Splenectomy; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000209:etiology