Patient physical characteristics and primary care physician decision making in preconception genetic screening.
BACKGROUND
There has been growing emphasis on preconception care as a strategy to improve maternal and child health since the 1980s. Increasingly, development of genetic tests will require primary care providers to make decisions about preconception genetic screening. Limited research has been conducted on how primary care providers interpret patients' characteristics and use constructs, such as ethnicity and race, to decide whom to offer preconception genetic screening.


OBJECTIVE
This report assessed the influence of patient characteristics on decisions to offer preconception genetic screening.


METHODS
A web-based survey of family physicians was conducted. Physicians reviewed a clinical vignette that was accompanied by a picture of either a black or a white patient. Physicians indicated whether they would offer genetic screening, and if yes, what tests they would offer and what factors influenced their decisions.


RESULTS
The majority (69.2%) of physicians reported that they would not offer genetic screening. Respondents who reviewed the vignette accompanied by a picture of the black patient were more likely to offer screening (35% vs. 26%, p = 0.0034) and rated race as more important to their decision to offer testing than those who viewed the picture of the white patient (76% vs. 49%, p < 0.0001).


CONCLUSIONS
Our findings suggest that patient race is important to physicians when making decisions about preconception genetic testing and that decision making is influenced by patients' physical characteristics. The reticence of physicians in this sample to offer preconception screening is an important finding for public health and clinical practice.
Bonham
V L
VL
Social and Behavioral Research Branch, National Human Genome Research Institute, NIH, Bethesda, Md. 20892-2152, USA. bonhamv@mail.nih.gov
Knerr
S
S
Feero
W G
WG
Stevens
N
N
Jenkins
J F
JF
McBride
C M
CM
D000328:Adult; D003657:Decision Making; D005260:Female; D005820:Genetic Testing; D006801:Humans; D008297:Male; D008875:Middle Aged; D058007:Physicians, Primary Care; D010818:Practice Patterns, Physicians'; D016742:Preconception Care