[Pleiotropic effects of small dozes simvastatin in patients of senile age with chronic heart failure].
The pleiotropic effects of simvastatin in a daily doze of 20 mg in persons of senile age with chronic heart failure were studied in the submitted work. The practical opportunity to reduce the risk of acute vascular events, improvement of vascular endothelium function and relative safety of application of the preparation in the specified dosage at persons of senile age is shown.
Pirogov
A L
AL
Al'tman
D A
DA
Ermak
E M
EM
Davydova
E V
EV
D000369:Aged, 80 and over; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000187:drug effects*; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008055:Lipids / Q000097:blood*; D008297:Male; D019821:Simvastatin / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography; D014664:Vasodilation / Q000187:drug effects*
D000960:Hypolipidemic Agents; D008055:Lipids; D019821:Simvastatin