Functional MRI study of brain function under resting and activated states.
Numerous magnetic resonance imaging (MRI) techniques have been developed with various imaging contrasts, which can be tightly linked to brain functions, electrophysiology and diseases. Recent MRI technology developments have resulted in several important functional MRI (fMRI) methods based on the blood oxygenation level dependent (BOLD) contrast. These fMRI methods have been applied to mapping brain activation in laminar level as well functional connectivity network in a resting brain. We have found a strong correlation between the spontaneous brain activity and BOLD fluctuation indicating a tight neurovascular relation.
Chen
Wei
W
Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, 2021 6th Street SE, Minneapolis, MN 55455, USA. wei@cmrr.umn.edu
Liu
Xiao
X
Zhu
Xiao-Hong
XH
Zhang
Nanyin
N
D000818:Animals; D001921:Brain / Q000473:pathology*; D001931:Brain Mapping / Q000295:instrumentation* / Q000379:methods; D002415:Cats; D003198:Computer Simulation; D003952:Diagnostic Imaging / Q000295:instrumentation / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D008959:Models, Neurological; D009415:Nerve Net; D010100:Oxygen / Q000378:metabolism; D051381:Rats
D010100:Oxygen