title: Histopathological, radiological and clinical aspects of the temporal assignment of scaphoid non-union.
abstract: OBJECTIVE
  The aim of this study was to evaluate the correlation between clinical, radiological and histopathological signs of scaphoid non-unions (SNU) with regard to the age of the fracture, primarily because this is relevant for therapy and compensation claims.
  
  
  METHODS
  Thirty-eight patients with SNU underwent clinical and radiological examination of the wrist prior to surgery. Preoperative X-rays of the wrist were analysed using the scores of Herbert and Fisher, Filan and Herbert, Trojan and Jahna, Gupta as well as scaphoid non-union advanced collapse. Sclerotic bone of the SNU was resected during surgery. Resected material was evaluated histologically after staining with hematoxylin-eosin and periodic acid-Schiff reaction. Radiological and histological examinations were performed by independent investigators in a blinded fashion.
  
  
  RESULTS
  The preoperative range of motion of the injured compared to the contralateral wrist was significantly reduced for the dorsi- and palmar flexion and for the radial and ulnar deviation; however, this reduction was not time dependent. There was no significant correlation between the radiological results and the age of the SNU, while fibrous tissue or fibrocartilage in the fracture gap was present in all cases. Significantly less fibrous or fibrocartilage bone cysts (p = 0.041) and bone remodelling (p = 0.031) were seen in older SNU (at 45 months). Definitive sclerotic bone covering of the fracture edges was significantly more common in older SNU (p = 0.035).
  
  
  CONCLUSIONS
  Radiological and most of the conventional histological findings do not correlate with time after initial injury.
authors: Department of Trauma and Reconstructive Surgery, University Hospital Carl Gustav Carus, Fetscherstrasse 74, Dresden, Germany. susanne.rein@web.de
authors: Susanne
authors: S
authors: Rein
authors: Uwe
authors: U
authors: Hanisch
authors: Stefan
authors: S
authors: Rammelt
authors: Günter
authors: G
authors: Schmidt
authors: Hans-Eberhardt
authors: HE
authors: Schaller
authors: Hans
authors: H
authors: Zwipp
authors: Matthias
authors: M
authors: Oehmke
authors: Stefan
authors: S
authors: Weindel
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005599:Fractures, Ununited / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D021361:Scaphoid Bone / Q000293:injuries*; D013997:Time Factors; D055815:Young Adult