Flexible multi electrode brain-machine interface for recording in the cerebellum.
A new type of chip based microelectrode for acute electrophysiological recordings in the CNS has been developed. It's designed to be adaptable to a multitude of specific neuronal environments, in this study the cerebellar cortex of rat and cat. Photolithographically patternened SU-8 is used to yield flexible and biocompatible penetrating shanks with gold leads. Electrodes with an impedance of about 300 kOmega at 1kHz have excellent signal to noise ratio in acute recordings in cat cerebellum.
Kohler
P
P
Lund University Medical Faculty, SE-221 84 Lund, Sweden. per.kohler@med.lu.se
Linsmeier
C Eriksson
CE
Thelin
J
J
Bengtsson
M
M
Jorntell
H
H
Garwicz
M
M
Schouenborg
J
J
Wallman
L
L
D000818:Animals; D002415:Cats; D002531:Cerebellum / Q000502:physiology*; D017076:Computer-Aided Design; D055119:Elastic Modulus; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005071:Evoked Potentials / Q000502:physiology*; D008839:Microelectrodes; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014584:User-Computer Interface