title: Gamma band oscillations under influence of bromazepam during a sensorimotor integration task: an EEG coherence study.
abstract: The goal of the present study was to explore the dynamics of the gamma band using the coherence of the quantitative electroencephalography (qEEG) in a sensorimotor integration task and the influence of the neuromodulator bromazepam on the band behavior. Our hypothesis is that the needs of the typewriting task will demand the coupling of different brain areas, and that the gamma band will promote the binding of information. It is also expected that the neuromodulator will modify this coupling. The sample was composed of 39 healthy subjects. We used a randomized double-blind design and divided subjects into three groups: placebo (n=13), bromazepam 3mg (n=13) and bromazepam 6 mg (n=13). The two-way ANOVA analysis demonstrated a main effect for the factors condition (i.e., C4-CZ electrode pair) and moment (i.e., C3-CZ, C3-C4 and C4-CZ pairs of electrodes). We propose that the gamma band plays an important role in the binding among several brain areas in complex motor tasks and that each hemisphere is influenced in a different manner by the neuromodulator.
authors: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Rio de Janeiro, RJ, Brazil.
authors: Daniel
authors: D
authors: Minc
authors: Sergio
authors: S
authors: Machado
authors: Victor Hugo
authors: VH
authors: Bastos
authors: Dionis
authors: D
authors: Machado
authors: Marlo
authors: M
authors: Cunha
authors: Mauricio
authors: M
authors: Cagy
authors: Henning
authors: H
authors: Budde
authors: Luis
authors: L
authors: Basile
authors: Roberto
authors: R
authors: Piedade
authors: Pedro
authors: P
authors: Ribeiro
mesh_terms: D000328:Adult; D001960:Bromazepam / Q000494:pharmacology*; D004311:Double-Blind Method; D004569:Electroencephalography; D005260:Female; D018757:GABA Modulators / Q000494:pharmacology*; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000187:drug effects* / Q000502:physiology; D009048:Motor Skills / Q000187:drug effects*; D010507:Periodicity; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000502:physiology; D055815:Young Adult
chemical_list: D018757:GABA Modulators; D001960:Bromazepam