title: A method for analysis of simultaneous equations in cell models.
abstract: Some models of cellular physiological functions are formulated as ordinary differential equations that contain multiple systems of simultaneous nonlinear equations. Simulation of such a model described in a declarative representation format requires determination of equations to be simultaneously solved with specification of independent and parameter variables in the model. In this report, a method for extracting systems of simultaneous equations in a cell model is presented. The present method analyzes a graph representation of a model and extracts the subgraphs that represent equation systems to be simultaneously solved, by efficiently interactive selection of independent variables of the model.
authors: ASTEM Research Institute of Kyoto, Kyoto 600-8813, Japan. simayosi@stem.or.jp
authors: Takao
authors: T
authors: Shimayoshi
authors: Akira
authors: A
authors: Amano
authors: Tetsuya
authors: T
authors: Matsuda
mesh_terms: D000465:Algorithms; D002468:Cell Physiological Phenomena; D022082:Cellular Structures; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D008954:Models, Biological; D008962:Models, Theoretical; D012984:Software; D049490:Systems Biology