[Axillary hyperhidrosis--efficacy and tolerability of an aluminium chloride antiperspirant. Prospective evaluation on 20 patients with idiopathic axillary hyperhidrosis].
BACKGROUND
The purpose of this study was to evaluate the efficacy and tolerability of aluminium chloride gel for treatment of axillary hyperhidrosis.


METHODS
A total of 20 patients aged 22-38 (mean age: 26.9+/-4.3) with idiopathic axillary hyperhidrosis were included and treated with an antiperspirant (Sweat-off, Sweat-off GmbH, Hügelsheim). Study duration was 42 days. Treatment efficacy was evaluated clinically, as well as by starch-iodine test, gravimetric analysis and evaluation of the skin surface pH.


RESULTS
After treatment there was a significant clinical improvement accompanied by significant qualitative and quantitative reduction of sweat as well as a significant reduction of skin surface pH. Except for slight skin irritation in 6 patients, there were no other side effects. Patient satisfaction improved markedly during the study.


CONCLUSIONS
Treatment of axillary hyperhidrosis with aluminium chloride is an effective, safe and inexpensive treatment modality.
Streker
M
M
Studiengang Kosmetikwissenschaft (FB 13), Universität Hamburg.
Reuther
T
T
Verst
S
S
Kerscher
M
M
D000328:Adult; D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000008:administration & dosage* / Q000009:adverse effects; D051520:Antiperspirants / Q000009:adverse effects / Q000627:therapeutic use*; D001252:Astringents / Q000008:administration & dosage; D001365:Axilla; D002712:Chlorides / Q000008:administration & dosage* / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D016896:Treatment Outcome
D017607:Aluminum Compounds; D051520:Antiperspirants; D001252:Astringents; D002712:Chlorides; D000077410:Aluminum Chloride