title: Regression of dilated perivascular spaces of the brain.
abstract: OBJECTIVE
  Perivascular, or Virchow-Robin, spaces of the brain represent interstitial fluid-filled spaces continuous with subpial spaces, and not invagination of cerebrospinal fluid-filled subarachnoid spaces. Regression of a dilated, or even giant, perivascular space occurs rarely. The purpose of this paper is to describe magnetic resonance imaging evidence of complete regression of dilated perivascular spaces (dPVSs).
  
  
  METHODS
  Patient 1 was a 76-year-old woman with right hemiparesis and aphasia from a left cranial vault meningioma infiltrating the superior sagittal sinus, and a left temporal lobe giant perivascular space. Patient 2 was a 70-year-old man with pituitary apoplexy, vasospasm, cerebral ischemia, and two dPVSs, one in the right temporal lobe, and one in the left anterior perforate substance. Patient 3 was a 78-year-old man with a generalized seizure, and a right temporal lobe dPVS.
  
  
  RESULTS
  In all the patients, temporal lobe giant or dPVSs underwent regression, following meningioma subtotal resection (patient 1) or pituitary lesion shrinkage (patient 2), or spontaneously (patient 3). In patient 2, the left anterior perforate substance dPVS was unchanged.
  
  
  CONCLUSIONS
  Temporal lobe giant or dPVSs may regress, eventually together with resection or regression of intracranial tumors, also distant from the PVSs. Cerebral edema does not seem the only factor influencing dilatation of PVSs.
authors: Unità Operativa Complessa di Neuroimmagini e Neurointerventistica, Dipartimento di Neuroscienze, Policlinico "Santa Maria alle Scotte", Azienda Ospedaliera Universitaria Senese, Viale Mario Bracci, 16, 53100, Siena, Italy. alfonsocerase@aliceposta.it
authors: Alfonso
authors: A
authors: Cerase
authors: Ignazio Maria
authors: IM
authors: Vallone
authors: Carmine Franco
authors: CF
authors: Muccio
authors: Carlo
authors: C
authors: Petrini
authors: Giorgio
authors: G
authors: Signori
authors: Carlo
authors: C
authors: Venturi
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D002555:Cerebrospinal Fluid; D003287:Contrast Media; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D013346:Subarachnoid Space / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media