title: Paternal dominance of trans-eQTL influences gene expression patterns in maize hybrids.
abstract: Heterosis refers to the superior performance of hybrid progeny relative to their inbred parents, but the mechanisms responsible are unknown. Hybrids between the maize inbred lines B73 and Mo17 exhibit heterosis regardless of cross direction. These reciprocal hybrids differ from each other phenotypically, and 30 to 50% of their genes are differentially expressed. We identified approximately 4000 expression quantitative trait loci (eQTL) that allowed us to identify markers linked to variation in expression. We found that over three-quarters of these eQTL act in trans (78%) and that 86% of these differentially regulate transcript accumulation in a manner consistent with gene expression in the hybrid being regulated exclusively by the paternally transmitted allele. This result suggests that widespread imprinting contributes to the regulation of gene expression in maize hybrids.
authors: Iowa State University, Ames, IA 50011, USA.
authors: Ruth A
authors: RA
authors: Swanson-Wagner
authors: Rhonda
authors: R
authors: DeCook
authors: Yi
authors: Y
authors: Jia
authors: Tim
authors: T
authors: Bancroft
authors: Tieming
authors: T
authors: Ji
authors: Xuefeng
authors: X
authors: Zhao
authors: Dan
authors: D
authors: Nettleton
authors: Patrick S
authors: PS
authors: Schnable
mesh_terms: D002874:Chromosome Mapping; D003433:Crosses, Genetic; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D018745:Genome, Plant; D018392:Genomic Imprinting; D006823:Hybrid Vigor; D006824:Hybridization, Genetic; D007178:Inbreeding; D020411:Oligonucleotide Array Sequence Analysis; D010641:Phenotype; D040641:Quantitative Trait Loci; D003313:Zea mays / Q000235:genetics* / Q000502:physiology