Glucose homeostasis and weight loss in morbidly obese patients undergoing banded sleeve gastrectomy: a prospective clinical study.
OBJECTIVE
To assess glucose homeostasis and weight loss in morbidly obese patients undergoing Silastic(R) ring sleeve gas-trectomy.


METHODS
This was a prospective clinical study. Thirty-three female patients with a mean body mass index (BMI) of 42.33 +/- 1.50 kg/m(2) (range: 40-45 kg/m(2)), a mean age of 36.7 +/- 9.4 years and a mean waist circumference of 118.7 +/- 5.98 cm were included in this study. Type 2 diabetes mellitus was observed in 11 patients (33.3%), and glucose intolerance was observed in 4 patients (12.1%). Mean plasma fasting glucose levels were 109.77 +/- 44.19 mg/dl (75-320) in the preoperative period. All Silastic(R) ring sleeve gastrectomy procedures were performed by the same surgical team using the same anesthetic technique. The patients were monitored for at least 12 months after surgery.


RESULTS
The mean weight of the patients decreased from 107.69 +/- 6.57 kg to 70.52 +/- 9.36 kg (p < 0.001), the mean BMI decreased to 27.4 +/- 2.42 kg/m(2) (p < 0.001), and the mean waist circumference decreased to 89.87 cm +/- 6.66 (p < 0.001) in the postoperative period. Excess BMI loss was 86.5 +/- 14.2%. Fasting glucose levels were reduced to 80.94 +/- 6.3 mg/dl (p < 0.001). Remission of diabetes and glucose intolerance was observed in all patients.


CONCLUSIONS
Silastic(R) ring sleeve gastrectomy was effective in promoting weight loss, waist circumference reduction and control of glucose homeostasis in morbidly obese patients.
Miguel
Gustavo Peixoto Soares
GP
Federal University of Espírito Santo - Vitória/ES, Brazil. gsoaresp@terra.com.br
Azevedo
Joao Luiz Moreira Coutinho
JL
Gicovate Neto
Carlos
C
Moreira
Cora Lavigne Castelo Branco
CL
Viana
Elaine Cristina
EC
Carvalho
Perseu Seixas
PS
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008875:Middle Aged; D009767:Obesity, Morbid / Q000378:metabolism* / Q000601:surgery; D011184:Postoperative Period; D011300:Preoperative Care; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D055105:Waist Circumference / Q000502:physiology; D015431:Weight Loss / Q000502:physiology*; D055815:Young Adult
D001786:Blood Glucose