title: Survival analysis after gastrostomy: a single-centre, observational study comparing radiological and endoscopic insertion.
abstract: OBJECTIVE
  Percutaneous endoscopic gastrostomy (PEG) using the pull through technique is the most widely used insertion method. An alternative is a per-oral image-guided gastrostomy (PIG), which may be advantageous in high-risk patients. As there are no large studies comparing PEG against PIG, we wished to analyse mortality after endoscopic or radiological gastrostomy insertion.
  
  
  METHODS
  Patients referred for a gastrostomy are prospectively included in a database along with demographic, biochemical and outcome data. Analysis of gastrostomy insertions from February 2004 to 2007 was performed with reference to method of insertion and 30-day outcome. Patients were subgrouped into cognitive impairment, dysphagic stroke, oropharygeal cancer, neurological cancer and other.
  
  
  RESULTS
  One hundred and seventy PIGs and 233 PEGs were inserted (mean age 62 years, 268 males). There were no differences in age between the PIG and the PEG group. The PIG 30-day mortality was 26 of 170 (15.3%) and the PEG 30-day mortality was 25 of 233 (10.7%) (P=0.17). One-year mortality was 92 of 170 (54.1%) for PIG and 131 of 233 (56.7%) for PEG (P=0.60). Subgroup analysis revealed higher 30-day mortality in patients with nasopharyngeal cancer undergoing PIG; 14 of 106 (13.2%) versus one of 69 (1.4%) (P=0.005). However, PIG patients were older than PEG patients (mean age 64 vs. 59.7 years, P=0.019) and had more comorbidities (21.1% in the PEG group and 37.7% in the PIG group).
  
  
  CONCLUSIONS
  Overall PIG and PEG seem to have similar 30-day and 1-year mortality rates. Our data suggest that clinicians may opt for either approach depending on technical considerations and local availability.
authors: Gastroenterology and Liver Unit, Royal Hallamshire Hospital, Sheffield, UK. jsleeds@hotmail.com
authors: John S
authors: JS
authors: Leeds
authors: Mark E
authors: ME
authors: McAlindon
authors: Julia
authors: J
authors: Grant
authors: Helen E
authors: HE
authors: Robson
authors: Fred K T
authors: FK
authors: Lee
authors: David S
authors: DS
authors: Sanders
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000401:mortality; D016099:Endoscopy, Gastrointestinal / Q000401:mortality*; D005260:Female; D005471:Fluoroscopy / Q000401:mortality*; D005774:Gastrostomy / Q000379:methods* / Q000401:mortality*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009380:Neoplasms, Nerve Tissue / Q000401:mortality; D009959:Oropharyngeal Neoplasms / Q000401:mortality; D020521:Stroke / Q000401:mortality; D016019:Survival Analysis