title: [Effect of initial periodontal therapy on chronic periodontitis patients with stable coronary heart disease].
abstract: OBJECTIVE
  To investigate the clinical results of initial periodontal therapy on chronic periodontitis patients with stable coronary heart disease.
  
  
  METHODS
  Thirty-two chronic periodontitis patients with stable coronary heart disease were included in this prospective study. All subjects received oral hygiene instruction, scaling and root planing and clinically monitored for 3 months. The clinical parameters, including plaque index (PLI), probing depth (PD), attachment loss (AL) and bleeding index (BI), were recorded at baseline and 3 months after treatment. Serum levels of high-sensitivity C-reactive protein (hs-CRP), cholesterol (CHO), triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and glucose (GLU) were also measured.
  
  
  RESULTS
  At 3 months after initial periodontal therapy, the mean PD of patients reduced from (3.95 +/- 0.15) mm to (2.93 +/- 0.21) mm (P < 0.01), the mean AL from (3.08 +/- 0.43) mm to (2.43 +/- 0.37) mm (P < 0.01), the percentage of sites with PD > or =5 mm from (22.37 +/- 6.88)% to (3.00 +/- 1.80)% (P < 0.01). hs-CRP significantly decreased at 3 months after treatment compared with baseline [(2.71 +/- 2.69) mg/L vs. (1.99 +/- 2.14) mg/L, P < 0.05]. CHO,TG, HDL, LDL and GLU decreased slightly (P > 0.05).
  
  
  CONCLUSIONS
  Initial periodontal therapy is effective for chronic periodontitis patients with stable coronary heart disease. After initial periodontal therapy, periodontal parameters improved significantly and serum levels of hs-CRP decreased.
authors: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors: Xiang-qing
authors: XQ
authors: Duan
authors: Xiang-ying
authors: XY
authors: Ouyang
authors: Rong
authors: R
authors: Hu
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D055113:Chronic Periodontitis / Q000150:complications* / Q000628:therapy*; D003327:Coronary Disease / Q000150:complications*; D006801:Humans; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D002097:C-Reactive Protein