title: The epidemiology of hospitalization with diarrhea in rural Kenya: the utility of existing health facility data in developing countries.
abstract: OBJECTIVE
  In developing countries where prospective surveillance is resource-intensive, existing hospital data can define incidence, mortality, and risk factors that can help target interventions and track trends in disease burden.
  
  
  METHODS
  We reviewed hospitalizations from 2001 to 2003 at all inpatient facilities in Bondo District, Kenya.
  
  
  RESULTS
  Diarrhea was responsible for 11.2% (n=2158) of hospitalizations. The annual incidence was 550 and 216 per 100,000 persons aged <5 and > or =5 years, respectively. The incidence was highest in infants (1138 per 100,000 persons), decreased in older children, peaked again among 20-29-year-olds (341 per 100,000), and declined among those > or =65 years (157 per 100,000). Female adults had higher incidence than males (rate ratio=1.84, 95% CI 1.61-2.10). Incidence decreased with distance from the district referral hospital (4.5% per kilometer, p<0.0001) and from the nearest inpatient facility (6.6% per kilometer, p=0.012). Case-fatality was high (8.0%), and was higher among adults than young children. Co-diagnosis with malaria, pneumonia, HIV, and tuberculosis was common. Peak diarrhea incidence fell one to two months after heavy rains.
  
  
  CONCLUSIONS
  The trends revealed here provide useful data for public health priority setting and planning, including preventative interventions. The utility of such data justifies renewed efforts to establish and strengthen health management information systems in developing countries.
authors: International Emerging Infections Program, Centers for Disease Control and Prevention, Unit 64112, APO, AE 09831, Kenya.
authors: Jeffrey A
authors: JA
authors: Tornheim
authors: Ayub S
authors: AS
authors: Manya
authors: Norbert
authors: N
authors: Oyando
authors: Stewart
authors: S
authors: Kabaka
authors: Ciara E
authors: CE
authors: O'Reilly
authors: Robert F
authors: RF
authors: Breiman
authors: Daniel R
authors: DR
authors: Feikin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003906:Developing Countries; D003967:Diarrhea / Q000453:epidemiology*; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007630:Kenya / Q000453:epidemiology; D008288:Malaria / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000453:epidemiology; D012307:Risk Factors; D012621:Seasons; D014376:Tuberculosis / Q000453:epidemiology