title: Automated detection of gastric slow wave events and estimation of propagation velocity vector fields from serosal high-resolution mapping.
abstract: High-resolution (HR; multi-electrode) recordings have led to detailed spatiotemporal descriptions of gastric slow wave activity. The large amount of data conveyed by the HR recordings demands an automated way of extracting the key measures such as activation times. In this study, a derivative-based method of identifying slow wave events was proposed. The raw signal was filtered using a second order Butterworth filter (low-pass; 10 Hz). The signal in each channel was differentiated and a threshold was taken as the 4.5x of the average of the negative first derivatives. An active event was defined where the first derivatives of the signal were more negative than the threshold. The accuracy of the method was validated against manually marked times, with a positive predictive value of 0.71. The detected activation times were interpolated using a second-order polynomial, the coefficients of which were evaluated using a previously developed least-square fitting method. The velocity fields were calculated, showing detailed spatiotemporal profile of slow wave propagation. The average of slow wave propagation velocity was 5.86 +/- 0.07 mms(-1).
authors: Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand. peng.du@auckland.ac.nz
authors: Peng
authors: P
authors: Du
authors: Wenlian
authors: W
authors: Qiao
authors: Greg
authors: G
authors: O'Grady
authors: John U
authors: JU
authors: Egbuji
authors: Wim
authors: W
authors: Lammers
authors: Leo K
authors: LK
authors: Cheng
authors: Andrew J
authors: AJ
authors: Pullan
mesh_terms: D000465:Algorithms; D000818:Animals; D004566:Electrodes; D001330:Electronic Data Processing; D004867:Equipment Design; D005769:Gastrointestinal Motility / Q000502:physiology*; D015233:Models, Statistical; D016065:Myoelectric Complex, Migrating / Q000502:physiology*; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted; D015398:Signal Transduction; D013270:Stomach / Q000502:physiology*; D013552:Swine; D013997:Time Factors