title: Fluoroscopy-guided topical application of mitomycin-C in a case of refractory esophageal stricture.
abstract: Esophageal strictures refractory to conservative treatment (balloon dilation, bouginage) are difficult to manage. Recently, some investigators reported great success using endoscopy-guided topical application of mitomycin-C to prevent scar formation and restenosis in children with benign esophageal strictures unresponsive to balloon dilation. Herein, the authors report a fluoroscopic approach for topical application of mitomycin-C in a case of refractory esophageal stricture after surgical repair in a child with congenital esophageal atresia. This technique is a feasible alternative to endoscopic techniques.
authors: Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8.
authors: John
authors: J
authors: Chung
authors: Bairbre
authors: B
authors: Connolly
authors: Jacob
authors: J
authors: Langer
authors: Margaret
authors: M
authors: Marcon
authors: Michael
authors: M
authors: Temple
authors: Joao G
authors: JG
authors: Amaral
mesh_terms: D000287:Administration, Topical; D002675:Child, Preschool; D002908:Chronic Disease; D004940:Esophageal Stenosis / Q000188:drug therapy*; D005260:Female; D005471:Fluoroscopy / Q000379:methods*; D006801:Humans; D016685:Mitomycin / Q000008:administration & dosage*; D015641:Radiography, Interventional / Q000379:methods*; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D016685:Mitomycin