title: Temporal lobe resection for refractory temporal lobe epilepsy at Auckland Hospital.
abstract: OBJECTIVE
  To analyse the long-term outcome of patients who underwent temporal lobe resection for intractable temporal lobe epilepsy at Auckland Hospital.
  
  
  METHODS
  We performed a retrospective analysis of 176 patients who underwent temporal lobe resection at Auckland Hospital, New Zealand between 1987 and 2007. We had at least 1 year of follow-up on 174 patients.
  
  
  RESULTS
  Overall 98/174 (56%) individuals were seizure-free at 1 year (Engel Class 1) with a marked improvement in quality of life. A further 61/174 (35%) had rare seizures or had significant improvement in seizure frequency (Engel Classes II or III). At last follow up (mean 4.3 years) 95/174 (55%) were seizure-free (Engel Class 1). Hippocampal sclerosis was the pathological finding in 129 patients. Surgical complications included 2 (1.1%) deaths, while 6 (3.4%) patients had symptomatic visual field defects, and 8 (4.5%) had other permanent neurological problems. A further 18 (10.3%) patients had temporary complications including infection, pulmonary embolus, and aseptic meningitis. New psychological symptoms occurred during the first year after surgery in 52% of 114 patients for whom we had detailed psychiatric assessments.
  
  
  CONCLUSIONS
  Temporal lobe resection is effective in controlling medically intractable seizures, but there are potentially serious complications that need to be considered when counselling patients for such a procedure.
authors: Department of Neurology, Auckland City Hospital, Auckland, New Zealand.
authors: Ravi
authors: R
authors: Suppiah
authors: Edward
authors: E
authors: Mee
authors: Elizabeth B
authors: EB
authors: Walker
authors: Lynair
authors: L
authors: Roberts
authors: Gregory
authors: G
authors: Finucane
authors: Peter S
authors: PS
authors: Bergin
mesh_terms: D000328:Adult; D038481:Anterior Temporal Lobectomy / Q000009:adverse effects; D004833:Epilepsy, Temporal Lobe / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D009520:New Zealand; D011183:Postoperative Complications; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome