title: Dunaliella as an attractive candidate for molecular farming.
abstract: Pharmaceutical recombinant proteins are widely used in human healthcare. At present, several protein expression systems are available to generate therapeutic proteins. These conventional systems have distinct advantages and disadvantages in protein yielding; in terms of ease of manipulation, the time required from gene transformation to protein purification, cost of production and scaling-up capitalization, proper folding and stability of active proteins. Depending on the research goal and priorities, a special system may be selected for protein expression. However, considering the limited variety of organisms currently used and their usage restrictions, there are still much more pharmaceutical proteins waiting to be economically and efficiently produced. Distinguished biological and technical features of microalgae Dunaliella such as inexpensive medium requirement, fast growth rate, the ease of manipulation, easy scaling up procedure, facility of milking in bioreactors and the ability of post-translational modifications make this microorganism an attractive candidate for molecular farming.
authors: Department of Food Biotechnology, Branch of West and North-West Region of Iran (Tabriz), Agricultural Biotechnology Research Institute of Iran, Karaj, Iran. Tabriz.biotechnology@gmail.com
authors: Abolfazl
authors: A
authors: Barzegari
authors: Mohammad Amin
authors: MA
authors: Hejazi
authors: Nahid
authors: N
authors: Hosseinzadeh
authors: Solat
authors: S
authors: Eslami
authors: Elnaz
authors: E
authors: Mehdizadeh Aghdam
authors: Mohammad Saeid
authors: MS
authors: Hejazi
mesh_terms: D015870:Gene Expression; D058086:Microalgae / Q000378:metabolism*; D058634:Molecular Farming / Q000379:methods*