Serotonin syndrome in the perioperative period.
Herein, we report a patient treated preoperatively with multiple psychiatric medications who developed serotonin syndrome (SS) during the perioperative period. SS was diagnosed using the Hunter Criteria (use of multiple serotonergic drugs preoperatively, hypertonia, and spontaneous clonus) and was presumed to have been triggered by the combination of perioperative and intraoperative serotonergic medications. It is essential that perioperative physicians, especially anesthesiologists, understand the risk factors, clinical scenario, and treatment of SS.
Altman
Christian Settle
CS
Department of Anesthesiology, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA. c-altman@md.northwestern.ed
Jahangiri
Mohammed Farid
MF
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D011183:Postoperative Complications / Q000139:chemically induced / Q000175:diagnosis*; D018490:Serotonin Agents / Q000008:administration & dosage / Q000009:adverse effects*; D020230:Serotonin Syndrome / Q000139:chemically induced / Q000175:diagnosis*
D018490:Serotonin Agents