title: Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma.
abstract: The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.
authors: Department of Anesthesia, Intensive Care and Pain Management, St. Antonius Ziekenhuis, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands. info@acidbase.org
authors: Paul W G
authors: PW
authors: Elbers
authors: Antonius J
authors: AJ
authors: Craenen
authors: Antoine
authors: A
authors: Driessen
authors: Marco C
authors: MC
authors: Stehouwer
authors: Luuk
authors: L
authors: Munsterman
authors: Miranda
authors: M
authors: Prins
authors: Mat
authors: M
authors: van Iterson
authors: Peter
authors: P
authors: Bruins
authors: Can
authors: C
authors: Ince
mesh_terms: D000328:Adult; D016887:Cardiopulmonary Resuscitation; D017809:Fatal Outcome; D006801:Humans; D007035:Hypothermia / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008833:Microcirculation; D008859:Microscopy, Polarization; D015701:Near Drowning / Q000503:physiopathology / Q000628:therapy*; D017694:Rewarming / Q000379:methods*