Selenocysteine is selectively taken up by red blood cells.
Both organic and inorganic forms of selenium are utilized in the biosynthesis of selenoproteins. Selenite is taken up by red blood cells and then returned to the plasma after reduction, but little is known about the metabolic fate of selenocysteine. We found that selenocysteine was taken up into red blood cells without decomposition into selenide.
Imai
Takeshi
T
Institute for Chemical Research, Kyoto University, Uji, Japan.
Mihara
Hisaaki
H
Kurihara
Tatsuo
T
Esaki
Nobuyoshi
N
D000042:Absorption; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D003545:Cysteine / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D017279:Selenocysteine / Q000378:metabolism*; D019810:Sodium Azide / Q000494:pharmacology
D006454:Hemoglobins; D017279:Selenocysteine; D019810:Sodium Azide; D003545:Cysteine