Pd/C-mediated synthesis of indoles in water.
We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the Pd/C-mediated coupling reaction.
Layek
Mohosin
M
Dr. Reddy's Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad 500049, India.
Lakshmi
Udaya
U
Kalita
Dipak
D
Barange
Deepak Kumar
DK
Islam
Aminul
A
Mukkanti
K
K
Pal
Manojit
M