title: Identification and characterization of an Ecl1-family gene in Saccharomyces cerevisiae.
abstract: We found that YGR146C of Saccharomyces cerevisiae encodes a functional homolog of Ecl1 that is involved in the chronological lifespan of Schizosaccharomyces pombe. When YGR146C is overexpressed, it extends the viability of wild-type S. cerevisiae cells after entry into the stationary phase, as in the case of Ecl1. We propose that Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.
authors: Laboratory of Molecular Microbiology, Graduate School of Bioagricultural Sciences, Nagoya University, Japan.
authors: Kenko
authors: K
authors: Azuma
authors: Hokuto
authors: H
authors: Ohtsuka
authors: Satoka
authors: S
authors: Mita
authors: Hiroshi
authors: H
authors: Murakami
authors: Hirofumi
authors: H
authors: Aiba
mesh_terms: D000595:Amino Acid Sequence; D002470:Cell Survival; D005800:Genes, Fungal / Q000235:genetics*; D005822:Genetic Vectors / Q000235:genetics; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000032:analysis / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
chemical_list: C547504:Ecl1 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins