Light-controlled retinal stimulation on rabbit using CMOS-based flexible multi-chip stimulator.
We implemented a light-sensing function on CMOS-based multi-chip stimulator for retinal prosthesis. Using the light-sensing circuitry attached to each stimulation electrode, the flexible multi-chip stimulator is capable of image-based patterned stimulation. We verified the function of the light-controlled decision based on the light intensity measured just beside the stimulation site. We also experimentally demonstrated in vivo retinal stimulation on rabbit's retina with light-controlled decision. The result of the present work is a simplified demonstration for the concept of retinal prosthesis with on-site imaging.
Tokuda
T
T
Nara Institute Science and Technology, Takayama-cho 8916-5, Ikoma, Nara, 630-0192, Japan. tokuda@ms.naist.jp
Takeuchi
Y
Y
Noda
T
T
Sasagawa
K
K
Nishida
K
K
Kitaguchi
Y
Y
Fujikado
T
T
Tano
Y
Y
Ohta
J
J
D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation*; D008027:Light; D010775:Photic Stimulation / Q000295:instrumentation*; D019736:Prostheses and Implants; D012160:Retina / Q000502:physiology*; D012666:Semiconductors; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*