title: Determinants of hair nicotine concentrations in nonsmoking women and children: a multicountry study of secondhand smoke exposure in homes.
abstract: The main purpose of this study was to identify and evaluate determinants of hair nicotine concentrations in nonsmoking women and children exposed to secondhand tobacco smoke at home. Hair samples were collected from nonsmoking women (n = 852) and from children (n = 1,017) <11 years of age living in households (n = 1,095) with smokers from 31 countries from July 2005 to October 2006. Participants' ages, activity patterns and socioeconomic characteristics including education and employment status, and hair treatment information were collected. Multilevel linear regression modeling was used to identify the main determinants of hair nicotine concentration measured by gas chromatography coupled with mass spectrometry. Increased indoor air nicotine concentration at home were associated with increased hair nicotine concentrations in nonsmoking women and children. This association was not changed after controlling for other explanatory variables. After controlling for age, length of exposure, and socioeconomic characteristics, hair nicotine concentrations in nonsmoking children and women were estimated to be increased by 3% and 1%, respectively, for a 1 microg/m(3) increase in air nicotine concentration. The association between children's exposure to secondhand tobacco smoke at home and hair nicotine concentration was stronger among younger children and children with longer exposure at home.
authors: Institute for Global Tobacco Control, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. srkim@jhsph.edu
authors: Sungroul
authors: S
authors: Kim
authors: Heather
authors: H
authors: Wipfli
authors: Ana
authors: A
authors: Navas-Acien
authors: Francesca
authors: F
authors: Dominici
authors: Erika
authors: E
authors: Avila-Tang
authors: Georgiana
authors: G
authors: Onicescu
authors: Patrick
authors: P
authors: Breysse
authors: Jonathan M
authors: JM
authors: Samet
mesh_terms: D000328:Adult; D016902:Air Pollution, Indoor / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006197:Hair / Q000737:chemistry*; D006798:Housing; D006801:Humans; D007390:International Agencies; D009538:Nicotine / Q000032:analysis*; D011379:Prognosis; D012307:Risk Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution; D009538:Nicotine