From floated to conventional confidence intervals for the relative risks based on published dose-response data.
A dose-response meta-analysis of epidemiological studies can encounter different types of confidence intervals (floated vs. conventional). This paper illustrates how to back calculate conventional confidence intervals from a set of relative risks reported with floated confidence intervals or floated standard errors. Furthermore, we provide an implementation of the formulas in a user-friendly program developed for Stata software. I exemplify the point using published data about alcohol intake and endometrial cancer incidence from the Million Women Study.
Orsini
Nicola
N
Karolinska Institutet, National Institute of Environmental Medicine, Nobelsvag 13, 17155 Stockholm, Sweden. nicola.orsini@ki.se
D000428:Alcohol Drinking / Q000453:epidemiology*; D016001:Confidence Intervals; D003936:Diagnosis, Computer-Assisted; D004305:Dose-Response Relationship, Drug; D016889:Endometrial Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D012306:Risk; D018570:Risk Assessment; D012984:Software; D014481:United States / Q000453:epidemiology