title: Femur metastasis in carcinoma of the uterine cervix: a rare entity.
abstract: OBJECTIVE
  We report the first case of isolated femur metastasis in a locally advanced cervical cancer (LACC) patients.
  
  
  METHODS
  A 40-year-old woman presenting with carcinoma of the uterine cervix, FIGO stage IIb was administered concomitant chemo-radiation and achieved clinical partial response. Before the planned surgery, she developed an isolated metastatic lytic lesion of the left femur. After surgical excision of metastasis, she refused palliative chemotherapy, and radiotherapy, and died 3 months later because of progression of the disease.
  
  
  CONCLUSIONS
  Bone metastasis is not so infrequent in patients with LACC. Because the prognosis of these patients is poor and most of them die within 1 year after the diagnosis of metastatic disease, the policy of treatment should be directed to maintain their quality of life.
authors: Gynecologic Oncology Unit, Department of Oncology, Catholic University of the Sacred Heart, L.go A. Gemelli, 1, 86100, Campobasso, Italy. giacomo.corrado@alice.it
authors: Giacomo
authors: G
authors: Corrado
authors: Salvatore
authors: S
authors: Santaguida
authors: Gianfranco
authors: G
authors: Zannoni
authors: Giovanni
authors: G
authors: Scambia
authors: Gabriella
authors: G
authors: Ferrandina
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000556:secondary*; D005260:Female; D005266:Femoral Neoplasms / Q000556:secondary*; D005269:Femur / Q000473:pathology*; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000473:pathology*