One-step synthesis and bioassay of N-phosphoramidophosphonates.
A simple one-step synthesis was accomplished for the preparation of N-phosphoramidophosphonates by a direct reaction of phosphoramidate (1) with heterocyclic aldehydes (2a-j) and dialkyl phosphites at 60-70 degrees C in the presence of tetramethylguanidine. The tetramethylguanidine not only catalyses this reaction but also helps to form pure products in high yields in lesser time. They exhibited good insecticidal and antioxidant properties.
Veera Narayana Reddy
Mudumala
M
Department of Chemistry, Sri Venkateswara University, Tirupati, India.
Balakrishna
Avula
A
Kumar
Mungara Anil
MA
Reddy
Gangireddygari Chandra Sekhar
GC
Sankar
Arigela Uma Ravi
AU
Reddy
Cirandur Suresh
CS
Krishna
Tirupati Murali
TM
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001681:Biological Assay / Q000379:methods*; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D010756:Phosphoric Acids / Q000138:chemical synthesis* / Q000737:chemistry; D018411:Spodoptera / Q000187:drug effects*
D000577:Amides; D000975:Antioxidants; D007306:Insecticides; D010756:Phosphoric Acids; C011067:phosphoramidic acid