Analysis of seventeen Y-chromosome STR loci in the Cape Muslim population of South Africa.
Two Y-STR genotyping systems were evaluated for usefulness in forensic casework in the Cape Muslim population of South Africa. Samples were collected from 105 males, and genotyped for 17 loci amplified in two multiplexes. Allele and haplotype frequencies were determined for nine Y-STR loci used to define the minimal haplotype (DYS19, DYS389-I, DYS389-II, DYS390, DYS391, DYS392, DYS393, and the duplicated locus DYS385) amplified in one multiplex, as well as for eight widely used loci amplified in a second multiplex and consisting of DYS449, DYS481, DYS518, DYS557, DYS570, DYS607, DYS612 and DYS614. When analysing the samples for all the loci, 104 unique haplotypes were obtained, and the discrimination capacity was 0.990. When considering only the nine Y-STRs included in the minimal haplotype, 91 unique haplotypes were obtained, and the discrimination capacity was 0.866. In the case of the remaining eight Y-STR loci, values of 97 and 0.924 were obtained, respectively.
Cloete
Kevin
K
Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa.
Ehrenreich
Liezle
L
D'Amato
María Eugenia
ME
Leat
Neil
N
Davison
Sean
S
Benjeddou
Mongi
M
D000483:Alleles; D041322:Chromosomes, Human, Y; D004247:DNA / Q000032:analysis*; D053803:Forensic Genetics / Q000379:methods*; D056426:Genetic Loci; D006239:Haplotypes; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000000981:diagnostic imaging; D020080:Tandem Repeat Sequences; D014463:Ultrasonography
D004247:DNA