title: Metastasis to eyelid as initial presentation of non-small cell carcinoma.
abstract: A 50-year-old man presented with a 1-month history of progressive eyelid swelling and intermittent hemorrhagic epiphora. A 1.2 x 1.3 x 0.7-cm friable hemorrhagic nodule was excised from the posterior eyelid surface. Histopathology revealed a poorly differentiated carcinoma. The patient underwent a systemic workup including CT of the lungs and was subsequently diagnosed with stage IV non-small cell carcinoma presumably of the lung. He received palliative radiation and chemotherapy and died 5 months after initial presentation. This report illustrates a case where metastatic eyelid disease was the presenting sign of hitherto undiagnosed lung cancer. It is followed by a review of clinical aspects of metastatic eyelid disease.
authors: Fallon Eye Clinic, Worcester, Massachusetts 01605, USA. Catharina.Latz@fallonclinic.org
authors: Catharina
authors: C
authors: Latz
authors: Qin
authors: Q
authors: Huang
authors: Mitesh K
authors: MK
authors: Kapadia
authors: Suzanne K
authors: SK
authors: Freitag
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011878:Radiotherapy; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents