title: N-acetylcysteine, reactive oxygen species and beyond.
authors: Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA. ssun@emory.edu
authors: Shi-Yong
authors: SY
authors: Sun
mesh_terms: D000111:Acetylcysteine / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D017209:Apoptosis / Q000235:genetics; D053446:CASP8 and FADD-Like Apoptosis Regulating Protein / Q000096:biosynthesis / Q000235:genetics; D045744:Cell Line, Tumor / Q000187:drug effects / Q000378:metabolism; D015536:Down-Regulation; D015973:Gene Expression Regulation, Leukemic / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins / Q000096:biosynthesis* / Q000235:genetics; D010084:Oxidation-Reduction; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis / Q000235:genetics; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000494:pharmacology*; D051636:X-Linked Inhibitor of Apoptosis Protein / Q000096:biosynthesis / Q000235:genetics
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D053446:CASP8 and FADD-Like Apoptosis Regulating Protein; C506386:CFLAR protein, human; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D017382:Reactive Oxygen Species; D013438:Sulfhydryl Compounds; D051636:X-Linked Inhibitor of Apoptosis Protein; C496866:XIAP protein, human; C551463:methyl 2-cyano-3,11-dioxooleana-1,12-dien-30-oate; C551464:methyl 2-cyano-3,12-dioxooleana-1, 12-dien-30-oate; D005978:Glutathione; D006034:Glycyrrhetinic Acid; D000111:Acetylcysteine