title: De novo HLA sensitization and antibody mediated rejection following pregnancy in a heart transplant recipient.
abstract: Here we report a case wherein both donor-specific and third-party, paternal, HLA class II specific antibodies developed following a spontaneous miscarriage resulting in antibody-mediated rejection in a patient who had undergone an orthotopic cardiac transplant six years earlier.
authors: Department of Cardiology, Harefield Hospital, Middlesex, UK.
authors: P J
authors: PJ
authors: O'Boyle
authors: J D
authors: JD
authors: Smith
authors: A J
authors: AJ
authors: Danskine
authors: H S
authors: HS
authors: Lyster
authors: M M
authors: MM
authors: Burke
authors: N R
authors: NR
authors: Banner
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology / Q000276:immunology; D000208:Acute Disease; D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006084:Graft Rejection / Q000209:etiology* / Q000276:immunology* / Q000473:pathology; D006680:HLA Antigens / Q000276:immunology*; D006681:HLA-D Antigens / Q000276:immunology; D006333:Heart Failure / Q000209:etiology; D016027:Heart Transplantation / Q000009:adverse effects* / Q000276:immunology* / Q000473:pathology; D006650:Histocompatibility Testing; D006801:Humans; D007519:Isoantigens / Q000276:immunology; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D018454:Spouses
chemical_list: D006680:HLA Antigens; D006681:HLA-D Antigens; D007519:Isoantigens