Promotive effects of resistant maltodextrin on apparent  absorption of calcium, magnesium, iron and zinc in rats.
BACKGROUND
It has been reported that low-viscous and fermentable dietary fiber and nondigestible oligosaccharides enhance mineral absorption. Resistant maltodextrin, nonviscous, fermentable and soluble source of dietary fiber, has several physiological functions. However, influence of resistant maltodextrin on mineral absorption is unclear.


OBJECTIVE
We conducted balance studies in rats to investigate effects of resistant maltodextrin and hydrogenated resistant maltodextrin on apparent mineral absorption.


METHODS
In experiment 1 (Exp. 1), 40 rats were fed test diets based on AIN-93G with or without resistant maltodextrin or hydrogenated resistant maltodextrin for 2 weeks. In experiment 2 (Exp. 2), 32 rats were cecectomized (CX) or sham-operated (Sham) and fed diets with or without hydrogenated resistant maltodextrin for 1 week.


RESULTS
In Exp. 1, ingestion of resistant maltodextrin and hydrogenated resistant maltodextrin dose-dependently enhanced apparent absorption rates of Ca, Mg, Fe and Zn, and increased cecal fermentation with cecal expansion. In Exp. 2, the absorption rates of Ca and Mg were significantly enhanced by ingestion of hydrogenated resistant maltodextrin in Sham group but not in CX group. The promotion of Fe and Zn absorption was not affected by cecectomy.


CONCLUSIONS
Ingestion of resistant maltodextrin and hydrogenated resistant maltodextrin increased apparent Ca and Mg absorptions dependent on cecal fermentation, while other mechanisms may also be involved in promotion of apparent Fe and Zn absorption by resistant maltodextrin.
Miyazato
Shoko
S
Matsutani Chemical Industry Co., Ltd., Itami, Hyogo, Japan. shoko-miyazato@matsutani.co.jp
Nakagawa
Chie
C
Kishimoto
Yuka
Y
Tagami
Hiroyuki
H
Hara
Hiroshi
H
D000704:Analysis of Variance; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002136:Calcium, Dietary / Q000378:metabolism*; D004032:Diet / Q000379:methods; D004043:Dietary Fiber / Q000494:pharmacology; D007408:Intestinal Absorption / Q000187:drug effects*; D019266:Iron, Dietary / Q000378:metabolism*; D008274:Magnesium / Q000378:metabolism*; D008297:Male; D011134:Polysaccharides / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015032:Zinc / Q000378:metabolism*
D002136:Calcium, Dietary; D004043:Dietary Fiber; D019266:Iron, Dietary; D011134:Polysaccharides; C008315:maltodextrin; D008274:Magnesium; D015032:Zinc