title: Peripheral T cell lymphoma with a high titer of proteinase-3-antineutrophil cytoplasmic antibodies that resembled Wegener's granulomatosis.
abstract: Here, we present a 54-year-old man with proptosis and swelling below the left eyelid. Laboratory findings showed high levels of PR3-ANCA and histological examination of the first biopsy revealed acute inflammation. Together with the findings of MRI, a diagnosis of WG was made. However, the disease progressed rapidly and histological examination of the second biopsy revealed infiltration of neoplastic T lymphocytes with aberrant loss of CD7. A final diagnosis of peripheral T cell lymphoma, not otherwise specified (WHO) was made, and complete remission was achieved by chemotherapy. This is a very rare case of T cell lymphoma with a high titer of PR3-ANCA.
authors: Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai.
authors: Tsuyoshi
authors: T
authors: Shirai
authors: Reiko
authors: R
authors: Takahashi
authors: Yumi
authors: Y
authors: Tajima
authors: Katsura
authors: K
authors: Kohata
authors: Joji
authors: J
authors: Yamamoto
authors: Hiroshi
authors: H
authors: Fujii
authors: Naruhiko
authors: N
authors: Takasawa
authors: Kenichi
authors: K
authors: Ishizawa
authors: Ryo
authors: R
authors: Ichinohasama
authors: Tomonori
authors: T
authors: Ishii
authors: Hideo
authors: H
authors: Harigae
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral / Q000097:blood* / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D053146:Myeloblastin / Q000097:blood*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D053146:Myeloblastin