title: Invited commentary.
authors: J Michael
authors: JM
authors: Berry
authors: Joel M
authors: JM
authors: Palefsky
mesh_terms: D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000473:pathology* / Q000821:virology; D001004:Anus Diseases / Q000175:diagnosis* / Q000821:virology; D001706:Biopsy; D003581:Cytodiagnosis / Q000379:methods*; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006679:HIV Seropositivity / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged