title: Transposon tools: worldwide landscape of intellectual property and technological developments.
abstract: DNA transposons are considered to be good candidates for developing tools for genome engineering, insertional mutagenesis and gene delivery for therapeutic purposes, as illustrated by the recent first clinical trial of a transposon. In this article we set out to highlight the interest of patent information, and to develop a strategy for the technological development of transposon tools, similar to what has been done in many other fields. We propose a patent landscape for transposon tools, including the changes in international patent applications, and review the leading inventors and applicants. We also provide an overview of the potential patent portfolio for the prokaryotic and eukaryotic transposons that are exploited by spin-off companies. Finally, we discuss the difficulties involved in tracing relevant state-of-the-art of articles and patent documents, based on the example of one of the most promising transposon systems, including all the impacts on the technological development of transposon tools.
authors: UFR des Sciences & Techniques, Université François Rabelais de Tours, GICC, Tours, France.
authors: Fabien
authors: F
authors: Palazzoli
authors: François-Xavier
authors: FX
authors: Testu
authors: Franck
authors: F
authors: Merly
authors: Yves
authors: Y
authors: Bigot
mesh_terms: D000818:Animals; D001709:Biotechnology; D002986:Clinical Trials as Topic; D004251:DNA Transposable Elements; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D018973:Intellectual Property; D038622:Internationality
chemical_list: D004251:DNA Transposable Elements