Blumeaxanthene II, a novel xanthene from Blumea riparia DC.
A novel xanthene (1), blumeaxanthene II, was isolated from the aerial parts of Blumea riparia (Bl.) DC., a Chinese medicinal plant with hemostatic properties, and its structure was determined by extensive spectroscopic analyses. This compound is the first example of a halogenated xanthene from a natural plant, and a biosynthetic pathway was proposed. Blumeaxanthene II was also tested against Bel-7404 cells in vitro but was found to be only weakly cytotoxic.
Huang
Li
L
Department of Chemistry and Chemical Engineering, Guangxi University, Nanning, People's Republic of China.
Lei
Ting
T
Lin
Cuiwu
C
Kuang
Xiaocong
X
Chen
Haiyan
H
Zhou
Hong
H
D019659:Asteraceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy; D015394:Molecular Structure; D035261:Plant Components, Aerial; D014966:Xanthenes / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use
D004365:Drugs, Chinese Herbal; D014966:Xanthenes; C554249:blumeaxanthene II