title: [Study on the natural foci of Marmota himalayana plague in Sichuan province].
abstract: OBJECTIVE
  To explore the existence of natural foci on Marmota himalayana plague in Sichuan province and to provide basis for prevention and control of the disease.
  
  
  METHODS
  Both epidemiological investigation and laboratory tests were used to provide the host animal and fleas of the vectors with Yersinia pestis carriers.
  
  
  RESULTS
  30 species of animals were found to belong to 10 orders. Ochotona curzoniae and M. himalayana were the most common ones while 7 species of the fleas belonged to 7 genera and 3 families. M. himalayana was the main reservoirs while Callopsylla dolabris and Oropsylla silantiewi served as vectors. The 13 Y. pestis were identified from 43 Marmota samples. 8 samples were identified under IHA, with the highest titer of herding-dogs serum as 1:10,240. 19 samples were F1 antigen positive using RIHA and the highest titer of M. himalayana serum was 1:409,600. The major foci was 4545 km2, distributed at Dege county in Sichuan province.
  
  
  CONCLUSIONS
  We have confirmed the existence of natural foci on M. himalayana plague in Sichuan province.
authors: Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
authors: Li-Mao
authors: LM
authors: Wang
authors: Zhi-Danba
authors: ZD
authors: Luo
authors: Qi
authors: Q
authors: Yue
authors: Yong-Jun
authors: YJ
authors: Duan
authors: Xiao-Ping
authors: XP
authors: Zhu
authors: Su-Ling
authors: SL
authors: Mao
authors: Lun-Guang
authors: LG
authors: Liu
authors: Hong
authors: H
authors: Wang
authors: Yi
authors: Y
authors: Liu
authors: Fei
authors: F
authors: Xie
authors: De-Gang
authors: DG
authors: Chen
authors: Kai-Hua
authors: KH
authors: Chen
authors: Bing
authors: B
authors: Deng
authors: Jun-Xing
authors: JX
authors: Kang
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000097:blood; D002681:China; D004197:Disease Reservoirs; D004199:Disease Vectors; D004285:Dogs; D006386:Hemagglutination Tests / Q000662:veterinary; D007303:Insect Vectors; D008392:Marmota / Q000382:microbiology*; D010930:Plague; D005423:Siphonaptera / Q000382:microbiology; D015010:Yersinia pestis / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D001426:Bacterial Proteins; C086725:caf1 protein, Yersinia pestis