Characterization of 1,3-alternate calix[4]arene-silica bonded stationary phases and their comparison to selected commercial columns by using principal component analysis.
Twelve calix[4]arene stationary phases in 1,3-alternate conformation, synthesized in the authors' laboratory, were characterized in terms of their surface coverage, hydrophobic selectivity, aromatic selectivity, shape selectivity, hydrogen bonding capacity and ion-exchange capacity. The set of tests commonly used for evaluation of commercially available stationary phases was applied to assess fundamental chromatographic properties of the calixarene phases. The new calixarene phases were compared to each other, to Caltrex and LiChrosorb C-18 columns. Principal component analysis has been used to provide comparison between 1,3-alternate calix[4]arene phases and commercially available phenyl, fluorophenyl and fluoroalkyl columns.
Sliwka-Kaszyńska
Magdalena
M
Department of Organic Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdańsk, Poland. kaszynski@interia.pl
Gorczyca
Grzegorz
G
Slebioda
Marek
M
D047250:Calixarenes / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D002852:Chromatography, Ion Exchange / Q000379:methods*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D007475:Ion Exchange Resins / Q000737:chemistry*; D025341:Principal Component Analysis / Q000379:methods*
D007475:Ion Exchange Resins; D047250:Calixarenes