title: Windowless microfluidic platform based on capillary burst valves for high intensity x-ray measurements.
abstract: We propose and describe a microfluidic system for high intensity x-ray measurements. The required open access to a microfluidic channel is provided by an out-of-plane capillary burst valve (CBV). The functionality of the out-of-plane CBV is characterized with respect to the diameter of the windowless access hole, ranging from 10 to 130 microm. Maximum driving pressures from 22 to 280 mbar corresponding to refresh rates of the exposed sample from 300 Hz to 54 kHz is demonstrated. The microfluidic system is tested at beamline ID09b at the ESRF synchrotron radiation facility in Grenoble, and x-ray scattering measurements are shown to be feasible and to require only very limited amounts of sample, <1 ml/h of measurements without recapturing of sample. With small adjustments of the present chip design, scattering angles up to 30 degrees can be achieved without shadowing effects and integration on-chip mixing and spectroscopy appears straightforward.
authors: Department of Micro and Nanotechnology, DTU Nanotech, Technical University of Denmark, Building 345east, DK-2800 Kongens Lyngby, Denmark.
authors: Asger Laurberg
authors: AL
authors: Vig
authors: Kristoffer
authors: K
authors: Haldrup
authors: Nikolaj
authors: N
authors: Enevoldsen
authors: Anil Haraksingh
authors: AH
authors: Thilsted
authors: Johan
authors: J
authors: Eriksen
authors: Anders
authors: A
authors: Kristensen
authors: Robert
authors: R
authors: Feidenhans'l
authors: Martin Meedom
authors: MM
authors: Nielsen
mesh_terms: D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D008853:Microscopy; D055616:Microtechnology; D014867:Water; D014961:X-Ray Diffraction; D014965:X-Rays
chemical_list: D014867:Water