title: Inherited thrombophilia in infertile women: implication in unexplained infertility.
abstract: Many studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677 T) was found in 100 infertile women with unexplained infertility when compared with 200 control fertile women without an infertility history.
authors: Infertility Center, Department of Surgery, Tor Vergata University Hospital, Rome, Italy. Casadei@med.uniroma2.it
authors: Luisa
authors: L
authors: Casadei
authors: Francesco
authors: F
authors: Puca
authors: Laura
authors: L
authors: Privitera
authors: Valentina
authors: V
authors: Zamaro
authors: Emanuela
authors: E
authors: Emidi
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005165:Factor V / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D006579:Heterozygote; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D015995:Prevalence; D011516:Prothrombin / Q000235:genetics*; D012307:Risk Factors; D019851:Thrombophilia / Q000150:complications / Q000453:epidemiology / Q000235:genetics; D055815:Young Adult
chemical_list: C095381:factor V Leiden; D005165:Factor V; D011516:Prothrombin; D042965:Methylenetetrahydrofolate Reductase (NADPH2)