[A negative first-line work-up of Raynaud's phenomenon: And what if it were cancer?].
Raynaud's phenomenon is a transient paroxysmal vasomotor phenomenon affecting the extremities including manifestations of ischemia. It is a common phenomenon in the general population. In a routine clinical situation, the first step is to differentiate Raynaud's disease from a secondary Raynaud's phenomenon, the latter requiring complementary investigations. We report here the case of an 80-year-old woman who presented a secondary Raynaud's phenomenon. First-line investigations remained negative. A mammography was performed and revealed breast cancer. Raynaud's phenomenon disappeared after treatment of the breast carcinoma and did not recur during the 2-year follow-up.
Auboire
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Service de médecine vasculaire, CHU de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France.
Landy
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S
Perrot
J-Y
JY
Maïza
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D
Le Hello
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C
D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D000369:Aged, 80 and over; D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D004967:Estrogens; D005260:Female; D005702:Galantamine / Q000627:therapeutic use; D006801:Humans; D008327:Mammography; D008408:Mastectomy; D009376:Neoplasms, Hormone-Dependent / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D009570:Nitriles / Q000627:therapeutic use; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000209:etiology*; D017035:Pravastatin / Q000627:therapeutic use; D011374:Progesterone; D018714:Radiotherapy, Adjuvant; D011928:Raynaud Disease / Q000188:drug therapy / Q000209:etiology*; D012621:Seasons; D014230:Triazoles / Q000627:therapeutic use; D014700:Verapamil / Q000627:therapeutic use
D018931:Antineoplastic Agents, Hormonal; D004967:Estrogens; D009570:Nitriles; D014230:Triazoles; D005702:Galantamine; D000077384:Anastrozole; D011374:Progesterone; D014700:Verapamil; D017035:Pravastatin