Clostridium septicum necrotizing fasciitis of the forefoot secondary to adenocarcinoma of the colon: Case report and review of the literature.
Clostridium septicum accounts for 1% of all reported clostridial infections. C septicum infections are most often nontraumatic in nature and associated with either an occult colonic or hematologic malignancy. The initial presentation of a C septicum infection can be relatively benign with rapid progression to fatality without emergent treatment. Presented is a case of necrotizing fasciitis of the forefoot caused by C septicum associated with an occult adenocarcinoma of the colon in a patient with uncontrolled diabetes. The process we used to achieve successful functional limb preservation based on rapid surgical intervention and use of a multidisciplinary approach to medical and surgical management of this patient is discussed in detail, as well as a through review of the literature regarding the association between malignancies and C septicum infections.
Schade
Valerie L
VL
Limb Preservation Complex Lower Extremity Surgery, Department of Surgery, Madigan Army Medical Center, Tacoma, WA, USA.
Roukis
Thomas S
TS
Haque
Mohamad
M
D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D003015:Clostridium Infections / Q000150:complications* / Q000382:microbiology; D052557:Clostridium septicum; D003110:Colonic Neoplasms / Q000150:complications* / Q000175:diagnosis; D048909:Diabetes Complications; D019115:Fasciitis, Necrotizing / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D005260:Female; D005534:Foot Diseases / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D005545:Forefoot, Human / Q000601:surgery; D006801:Humans; D008875:Middle Aged