title: Transient renal insufficiency following dipyrone overdose.
abstract: OBJECTIVE
  To describe the incidence of acute renal insufficiency after dipyrone overdose in children.
  
  
  METHODS
  The medical records of all patients < or =18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyrone overdose were compared with all the other patients.
  
  
  RESULTS
  235 cases were included in the final analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insufficiency. One other patient who did not receive dipyrone also developed transient renal insufficiency.
  
  
  CONCLUSIONS
  Dipyrone overdose is frequent and may cause acute non-oliguric renal insufficiency. Renal function should be monitored in such patients.
authors: Pediatric Intensive Care Unit, Assaf Harofeh Medical Center, Zerifi n, Israel.
authors: Ibrahim
authors: I
authors: Abu-Kishk
authors: Michael
authors: M
authors: Goldman
authors: Yair
authors: Y
authors: Mordish
authors: Matitiahu
authors: M
authors: Berkovitch
authors: Eran
authors: E
authors: Kozer
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000506:poisoning*; D002648:Child; D004177:Dipyrone / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004177:Dipyrone