title: Modulation of arousal regulation with central thalamic deep brain stimulation.
abstract: To investigate the effects of central thalamic deep brain stimulation (CT/DBS) on behavior and frontal cortical function, we conducted experiments in an awake, behaving macaque monkey performing tasks that required sustained attention and working memory. Results of this preliminary study revealed that CT/DBS can lead to an improvement, a decrement, a mixed or have no effect on behavior.
authors: Physiology, Biophysics and Systems Biology Department, Weill Cornell Graduate School of Biomedical Sciences, NY, NY 10021, USA. sut2006@med.cornell.edu
authors: Sudhin A
authors: SA
authors: Shah
authors: Jonathan L
authors: JL
authors: Baker
authors: Jae-Wook
authors: JW
authors: Ryou
authors: Keith P
authors: KP
authors: Purpura
authors: Nicholas D
authors: ND
authors: Schiff
mesh_terms: D000328:Adult; D000818:Animals; D001143:Arousal; D001288:Attention; D001519:Behavior; D001522:Behavior, Animal; D001921:Brain / Q000473:pathology*; D046690:Deep Brain Stimulation / Q000379:methods*; D004594:Electrophysiology / Q000379:methods; D006801:Humans; D008251:Macaca; D008297:Male; D008570:Memory, Short-Term; D009434:Neural Pathways; D009474:Neurons / Q000473:pathology