title: Putting the brakes on dietary fat breakdown.
abstract: Dietary lipid digestion is critical for body fat storage control, but little is known about the regulation of genes involved in fat breakdown and absorption in the gastrointestinal tract. A Drosophila study (Sieber and Thummel, 2009 [this issue of Cell Metabolism]) now demonstrates that the orphan nuclear receptor DHR96 adjusts fat storage in flies by tuning gastric lipase expression.
authors: Department of Molecular Developmental Biology, Max-Planck-Institut für biophysikalische Chemie, 37077 Göttingen, Germany. rkuehnl@gwdg.de
authors: Ronald P
authors: RP
authors: Kühnlein