Statins in influenza: time for a controlled clinical study.
Mexico recently experienced the impact of an influenza epidemic. This outbreak, the H1N1 strain, affected a large number of citizens and caused panic, economic instability and increased health care costs to the federal government and public and private institutions. Influenza outbreaks are periodic. They may or may not be seasonal, and severity of the disease is linked to host immunity and to the virus strain. In the event of a pandemic as happened in 1918, it is estimated that approximately 175-350 million people may die, and health systems would face a catastrophic situation due to the insufficiency of antivirals and vaccines, as well as affecting hospital infrastructure.
Carrillo-Esper
Raúl
R
Unidad de Terapia Intensiva, Fundación Clínica Médica Sur, Puente de Piedra 150 Col. Toriello Guerra Del. Tlalpan, 14150 México, D.F., Mexico. seconcapcma@mail.medinet.net.mx
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003253:Consultants; D013502:General Surgery; D006301:Health Services Needs and Demand; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D007107:Immune System / Q000187:drug effects; D007251:Influenza, Human / Q000188:drug therapy*; D008800:Mexico; D012955:Societies, Medical
D000893:Anti-Inflammatory Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors