title: The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.
abstract: Since the cloning of the first membrane transporter, our understanding of the role of transporters in clinical drug disposition and response has grown enormously. In parallel, large-scale genome-wide variation studies and the emerging field of pharmacogenomics have ushered in a new understanding of variations in drug response. At the crossroads of pharmacogenomics and transporter biology is the National Institutes of Health-funded Pharmacogenomics of Membrane Transporters (PMT) project, centered at the University of California, San Francisco.
authors: Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, USA.
authors: D L
authors: DL
authors: Kroetz
authors: S W
authors: SW
authors: Yee
authors: K M
authors: KM
authors: Giacomini
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005787:Gene Frequency / Q000235:genetics; D015894:Genome, Human / Q000235:genetics; D023281:Genomics / Q000379:methods / Q000639:trends*; D006801:Humans; D026901:Membrane Transport Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D010597:Pharmacogenetics / Q000379:methods / Q000639:trends*
chemical_list: D026901:Membrane Transport Proteins