title: A Simple Procedure for C-C Bond Cleavage of Aromatic and Aliphatic Epoxides with Aqueous Sodium Periodate Under Ambient Conditions.
abstract: The sodium periodate mediated oxidative cleavage of the C-C bond of twelve epoxides is reported with yields of the corresponding carbonyl compounds in up to 91%. This is a two-step reaction that proceeds through a rate-limiting epoxide opening to a vicinal diol that is cleaved in situ to the corresponding carbonyl compound. This method serves as a chemoselective alternative to ozonolysis.
authors: University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064.
authors: Caitlin M
authors: CM
authors: Binder
authors: Darryl D
authors: DD
authors: Dixon
authors: Erik
authors: E
authors: Almaraz
authors: Marcus A
authors: MA
authors: Tius
authors: Bakthan
authors: B
authors: Singaram