title: The role of diclofenack on inducing of aplasia cutis congenita: a case report.
abstract: BACKGROUND
  Aplasia cutis congenita is a disorder where e newborn child is missing skin from certain areas. It is a rare condition with no particular race or sex more at risk. May occur by itself or be associated with other physical syndromes or disorders. A classification system exists for aplasia cutis congenital consisting of 9 groups, based on the number and location of the skin defects and the presence or absence of other malformations. Causes of aplasia congenital could be heredity, teratogenic substances, placental infarcts, intrauterine infections, ectodermal dysplasias etc. Diagnosis is made based on the clinical findings. Prognosis depends of the other organs malfunction level and lesions size.
  
  
  METHODS
  Our case was an 22 months old Albanian girl, who was recommended to dermatology for a consultation by a pediatric surgeon because of the changes she had on her parietal part of the scalp with missing hair areas. The child has stenosis congenita ani and to her was installed stoma. In order to investigate other accompanied anomalies of the disease, there are made specific consults by neurologist, orthopedist, cardiologist, nephrologists and citogenetics.
  
  
  CONCLUSIONS
  It was found out a minor visual discoordination, Sy Floppy, Digiti V superductus pedis bill. Laxitas articularum generalisata. It was a great challenge for us to find out that during the first trimester of the pregnancy (unplanned pregnancy), her mother used Diclofenac. Since there is limited information regarding to teratogenic effects of diclofenac, we considered it interesting to present this case.
authors: Department of Dermatology, University Clinical Centre of Kosovo, Prishtina, Republic of Kosovo. laurapajaziti@yahoo.com
authors: Laura
authors: L
authors: Pajaziti
authors: Syzana
authors: S
authors: Rexhepi
authors: Ylfete
authors: Y
authors: Shatri-Muça
authors: Mybera
authors: M
authors: Ferizi