title: In-vivo measurement of relationship between applied current amplitude and current density magnitude from 10 mA to 110 mA.
abstract: Current density imaging (CDI) is a magnetic resonance imaging (MRI) technique used to quantitatively measure current density vectors throughout the volume of an object/subject placed in the MRI system. Electrical current pulses are applied externally to the object/subject and are synchronized with the MRI sequence. In this work, CDI is used to measure average current density magnitude in the torso region of an in-vivo piglet for applied current pulse amplitudes ranging from 10 mA to 110 mA. The relationship between applied current amplitude and current density magnitude is linear in simple electronic elements such as wires and resistors; however, this relationship may not be linear in living tissue. An understanding of this relationship is useful for research in defibrillation, human electro-muscular incapacitation (e.g. TASER(R)) and other bioelectric stimulation devices. This work will show that the current amplitude to current density magnitude relationship is slightly nonlinear in living tissue in the range of 10 mA to 110 mA.
authors: Field Metrica Inc., Toronto, ON M8V 1W1 Canada. tdemonte@fieldmetrica.com
authors: Tim P
authors: TP
authors: DeMonte
authors: Dinghui
authors: D
authors: Wang
authors: Weijing
authors: W
authors: Ma
authors: Jia-Hong
authors: JH
authors: Gao
authors: Michael L G
authors: ML
authors: Joy
mesh_terms: D000818:Animals; D003198:Computer Simulation; D003201:Computers; D004553:Electric Conductivity; D004558:Electric Stimulation; D004560:Electricity; D004562:Electrocardiography / Q000379:methods; D004572:Electrolysis; D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D012867:Skin / Q000473:pathology; D013552:Swine