[Virilization of a post-menopausal woman. Diagnostic and therapeutic considerations].
Virilizing tumors are rare disorders that commonly develop in the adrenal cortex or the ovaries. Because these tumors are usually millimetric, androgen-secreting ovarian tumors can be particularly difficult to identify through commonly available imaging techniques and can thus pose a diagnostic challenge. We present the case of a 71-year-old woman who presented with severe clinical hyperandrogenism and biochemical traits suggestive of an ovarian source but who was diagnosed with a 10-cm adrenal mass.
Montoya
Teresa
T
Servicio de Endocrinología y Nutrición, Hospital Infanta Elena, Madrid, España. tmonalv@alumni.unav.es
Guijarro
Guadalupe
G
Elvira
Rosa
R
Olivar
Juana
J
D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000315:Adrenalectomy; D000368:Aged; D000728:Androgens / Q000097:blood / Q000378:metabolism; D002295:Carcinoma, Transitional Cell; D017373:Cyproterone Acetate / Q000627:therapeutic use; D003907:Dexamethasone; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors; D006065:Gonadotropins, Pituitary / Q000502:physiology*; D006801:Humans; D033162:Incidental Findings; D016609:Neoplasms, Second Primary / Q000150:complications / Q000175:diagnosis*; D010049:Ovarian Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D017698:Postmenopause; D017329:Triptorelin Pamoate; D001749:Urinary Bladder Neoplasms; D014770:Virilism / Q000097:blood / Q000209:etiology*
D000728:Androgens; D006065:Gonadotropins, Pituitary; D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone; D017373:Cyproterone Acetate; D003907:Dexamethasone