title: Engineering NIR dyes for fluorescent lifetime contrast.
abstract: The excited state of an organic molecule is a crossroads which can lead to many directions, such as non-radiative emission as heat, fluorescence, intersystem crossing and phosphorescence. Due to the unpredictable nature of the excited molecular structure, manipulation of this represents significant challenges for physicists and chemists. However, the successful management of the excited state provides a number of benefits with innumerable applications to fields like photonics and medicine. One such property of the excited state with powerful ramifications in medical diagnostics is fluorescence lifetime.
authors: Washington University School of Medicine, Department of Radiology, St. Louis, MO 63110, USA. berezinm@mir.wustl.edu
authors: Mikhail Y
authors: MY
authors: Berezin
authors: Hyeran
authors: H
authors: Lee
authors: Walter
authors: W
authors: Akers
authors: Kevin
authors: K
authors: Guo
authors: Reece J
authors: RJ
authors: Goiffon
authors: Adah
authors: A
authors: Almutairi
authors: Jean M J
authors: JM
authors: Fréchet
authors: Samuel
authors: S
authors: Achilefu
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000737:chemistry*; D015195:Drug Design; D005456:Fluorescent Dyes / Q000737:chemistry*; D007089:Image Enhancement / Q000379:methods*; D007700:Kinetics; D051379:Mice; D008856:Microscopy, Fluorescence / Q000379:methods*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013997:Time Factors; D051598:Whole Body Imaging / Q000379:methods*
chemical_list: D003287:Contrast Media; D005456:Fluorescent Dyes