[Application of near infrared spectroscopy in quality control of excipients of traditional Chinese medicine].
OBJECTIVE
To apply the near infrared spectroscopy in quality control for excipients of traditional Chinese medicine (TCM).


METHODS
A new type of transmittance and reflectance integration sphere accessory and a transmittance accessory were used to collect the spectra of processed honey and rice wine, respectively. Determination method of reducing sugar and ethanol in processed honey were established with partial least squares (PLS).


RESULTS
The correlation coefficients (r), the root mean square error of calibration (RMSEC) and the root mean square error of prediction (RMSEP) of the proposed models were 0.9593, 1.00% and 1.19% for reducing sugar; 0.9529, 0.17% and 0.24% for ethanol.


CONCLUSIONS
The proposed method is fast, non-destructive, simple and accurate, and can be applied to at-spot detection,
Nie
Lixing
L
National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China. nielixing@163.com
Wang
Gangli
G
Li
Zhimeng
Z
Lin
Ruichao
R
D005079:Excipients / Q000737:chemistry*; D006722:Honey / Q000032:analysis*; D008516:Medicine, Chinese Traditional; D012275:Oryza / Q000737:chemistry*; D011786:Quality Control; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D014920:Wine / Q000032:analysis*
D005079:Excipients