title: Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion.
abstract: BACKGROUND
  The changes of perifoveal capillary blood flow velocity (BFV), visual acuity, and retinal thickness after pars plana vitrectomy (PPV) have been unclear in patients with branch retinal vein occlusion (BRVO) and macular edema.
  
  
  METHODS
  In a prospective study, PPV was performed on six eyes of six consecutive BRVO patients with macular edema (two women and four men; mean age: 66.3 +/- 5.0 years). Patients were examined preoperatively and 6 months postoperatively. BFV was measured by fluorescein angiography using a scanning laser ophthalmoscope and the tracing method. Macular thickness was examined by optical coherence tomography. Visual acuity was measured preoperatively and postoperatively, and data were converted to the logarithm of the minimum angle of resolution (logMAR).
  
  
  RESULTS
  In all six treated eyes, the macular thickness decreased significantly compared with before PPV (464 +/- 98 microm versus 224 +/- 55 microm, P = 0.0082), mean BFV increased significantly compared with before PPV (1.14 +/- 0.14 mm/sec versus 1.46 +/- 0.21 mm/sec, P = 0.0013), and mean logMAR decreased significantly compared with before PPV (0.57 +/- 0.34 versus 0.17 +/- 0.21, P = 0.0036).
  
  
  CONCLUSIONS
  PPV may improve perifoveal microcirculation and the visual prognosis in BRVO patients with macular edema.
authors: Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women's Medical University, 477-96, Owada-shinden, Yachiyo, Chiba, 276-8524, Japan. nomahide@tymc.twmu.ac.jp
authors: Hidetaka
authors: H
authors: Noma
authors: Hideharu
authors: H
authors: Funatsu
authors: Kumi
authors: K
authors: Sakata
authors: Tatsuya
authors: T
authors: Mimura
authors: Sadao
authors: S
authors: Hori
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000098:blood supply*; D008269:Macular Edema / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D011446:Prospective Studies; D012170:Retinal Vein Occlusion / Q000503:physiopathology* / Q000601:surgery; D012171:Retinal Vessels / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy