title: Two new isopimarane diterpenes from the feces of Trogopterus xanthipes.
abstract: Chemical investigation of Trogopterus Feces has led to the isolation of two new isopimarane diterpenes, wulingzhic acid A (1) and wulingzhic acid B (2). Their structures were elucidated by chemical and extensive spectral analysis. Compounds 1 and 2 exhibited weak activity of antithrombin and moderate activity of antiplatelet aggregation in vitro.
authors: Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Traditional Chinese Medicine, Nanjing, China.
authors: Nian-Yun
authors: NY
authors: Yang
authors: Wei-Wei
authors: WW
authors: Tao
authors: Min
authors: M
authors: Zhu
authors: Jin-Ao
authors: JA
authors: Duan
authors: Jian-Guo
authors: JG
authors: Jiang
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000991:Antithrombins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005243:Feces / Q000737:chemistry*; D008516:Medicine, Chinese Traditional; D010974:Platelet Aggregation / Q000187:drug effects*; D012589:Sciuridae
chemical_list: D000925:Anticoagulants; D000991:Antithrombins; D004224:Diterpenes; C554151:wulingzhic acid A; C554152:wulingzhic acid B