[Report of the first case of influenza A (H1N1) in mainland China].
OBJECTIVE
To investigate the clinical characteristics and management of the first confirmed imported case of influenza A (H1N1) infection in mainland China.


METHODS
The description of the clinical manifestations, clinical management, infection preventing and controlling strategies were reviewed.


RESULTS
The 30-years old male patient came back from U.S.A. and with mild influenza-like symptoms developed. He had had a close contact history with a patient with "common cold" 4 d before onset of illness. Influenza A (H1N1) virus newly confirmed in North American was detected in the throat swab samples taken from this patient by real-time PCR and sequencing comparison. His symptoms ameliorated soon after administration of oseltamivir. The temperature was back to normal on the second day with oseltamivir. Nucleic acid of Influenza A (H1N1) virus was undetectable after 3 d with oseltamivir management. The patient was discharged on the 7 d after hospitalization.


CONCLUSIONS
The clinical presentations of this imported case with Influenza A(H1N1) infection suggest that A(H1N1) infection manifests as flu-like symptoms in the healthy young people with a mild clinical course and a good prognosis. Early identification, early diagnosis and intervention with oseltamivir might be an effective clinical strategies for management of this emerging infectious disease.
Chen
Hong
H
The Infectious Disease Hospital of Chengdu, Chengdu 610061, China.
Liu
Ya-ling
YL
He
Sheng-hua
SH
Zeng
Yi-lan
YL
Wang
Guang-fa
GF
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D002681:China / Q000453:epidemiology; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use; D011379:Prognosis
D000998:Antiviral Agents; D053139:Oseltamivir