title: Effects of computer monitor-emitted radiation on oxidant/antioxidant balance in cornea and lens from rats.
abstract: OBJECTIVE
  This study aims to investigate the possible effects of computer monitor-emitted radiation on the oxidant/antioxidant balance in corneal and lens tissues and to observe any protective effects of vitamin C (vit C).
  
  
  METHODS
  Four groups (PC monitor, PC monitor plus vitamin C, vitamin C, and control) each consisting of ten Wistar rats were studied. The study lasted for three weeks. Vitamin C was administered in oral doses of 250 mg/kg/day. The computer and computer plus vitamin C groups were exposed to computer monitors while the other groups were not. Malondialdehyde (MDA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) activities were measured in corneal and lens tissues of the rats.
  
  
  RESULTS
  In corneal tissue, MDA levels and CAT activity were found to increase in the computer group compared with the control group. In the computer plus vitamin C group, MDA level, SOD, and GSH-Px activities were higher and CAT activity lower than those in the computer and control groups. Regarding lens tissue, in the computer group, MDA levels and GSH-Px activity were found to increase, as compared to the control and computer plus vitamin C groups, and SOD activity was higher than that of the control group. In the computer plus vitamin C group, SOD activity was found to be higher and CAT activity to be lower than those in the control group.
  
  
  CONCLUSIONS
  The results of this study suggest that computer-monitor radiation leads to oxidative stress in the corneal and lens tissues, and that vitamin C may prevent oxidative effects in the lens.
authors: Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Department of Ophthalmology, Ankara, Turkey. mehmetbalci2001@yahoo.com
authors: Mehmet
authors: M
authors: Balci
authors: Mehmet
authors: M
authors: Namuslu
authors: Erdinç
authors: E
authors: Devrim
authors: Ilker
authors: I
authors: Durak
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D003201:Computers; D003315:Cornea / Q000378:metabolism / Q000528:radiation effects*; D005260:Female; D007908:Lens, Crystalline / Q000378:metabolism* / Q000528:radiation effects*; D016877:Oxidants / Q000378:metabolism*; D011827:Radiation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D016877:Oxidants