title: Late-acquired stent malapposition after sirolimus-eluting stent implantation following acute coronary syndrome: angiographic, IVUS, OCT and coronary angioscopic observation.
abstract: Drug-eluting stents (DES) have been shown to significantly reduce the incidence of restenosis and target lesion revascularization in a wide variety of clinical situations. DES have also been shown to significantly reduce neointimal hyperplasia as compared to bare-metal stents. However, the antiproliferative properties of DES also delay vascular healing and have been associated with stent malapposition, hypersensitivity reactions and late stent thrombosis. Stent thrombosis could result in myocardial infarction or death. We describe here a case report of late stent malapposition following sirolimus-eluting stent implantation observed by angiography, intravascular ultrasound, optical coherence tomography and angioscopy.
authors: The Cardiothoracic Centre, Liverpool, United Kingdom. sudhirrathore@hotmail.com
authors: Sudhir
authors: S
authors: Rathore
authors: Mitsuyasu
authors: M
authors: Terashima
authors: Takahiko
authors: T
authors: Suzuki
mesh_terms: D054058:Acute Coronary Syndrome / Q000628:therapy*; D000328:Adult; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000379:methods*; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000453:epidemiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005548:Foreign-Body Migration / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D012307:Risk Factors; D020123:Sirolimus; D041623:Tomography, Optical Coherence; D018084:Ultrasonography, Interventional
chemical_list: D020123:Sirolimus