title: Synthesis of a new family of 2-ethylidene-gamma-unsaturated delta-amino esters via microwave activated Stille coupling.
abstract: A simple approach to a new family of enantiomerically enriched polyunsaturated t-Boc-protected-delta-amino esters is described, via microwave promoted Stille coupling of (Z)-methyl-2-bromobutenoate with stannylated allylamines. The reaction conditions are mild and selective and disclose a simple way to 1-substituted butenoates of defined geometry.
authors: Dipartimento di Chimica Organica Ugo Schiff, University of Florence, via della Lastruccia 13, 50019, Sesto Fiorentino, Florence, Italy.
authors: Gabriella Barozzino
authors: GB
authors: Consiglio
authors: Francesca
authors: F
authors: Gaggini
authors: Alessandro
authors: A
authors: Mordini
authors: Gianna
authors: G
authors: Reginato
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D004952:Esters