title: Chemo-enzymatic synthesis and functional analysis of natural and modified glycostructures.
abstract: The advancing field of glycomics is driven by the development of new analysis and synthesis techniques and novel strategies such as metabolic glyco-labeling. In this review we will present strategies for tailoring chemo-enzymatic glycosyltransfer reactions, screening methods such as carbohydrate-based micro-arrays, and metabolic glyco-engineering as a strategy to visualize biological recognition processes for the development of carbohydrate-based vaccines.
authors: Department of Organic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
authors: Arne
authors: A
authors: Homann
authors: Jürgen
authors: J
authors: Seibel
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D006027:Glycosides / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D016695:Glycosyltransferases / Q000378:metabolism*; D015394:Molecular Structure
chemical_list: D001688:Biological Products; D006027:Glycosides; D016695:Glycosyltransferases