[The role of gene-environment interaction in the development of eating disorders].
The biological research predominant in the last decades have not brought a solution in the discovery of risk factors contributing to the development of eating disorders, and elaborating a more effective therapy. The large amount of molecular genetic studies, however, by showing the various genetic vulnerability, contributed significantly to recognizing a more specific effect of the environmental factors. The authors evaluate the genetic studies of eating disorders and present environmental factors having a role in the development of eating disorders. They report about recently published data of gene-environment interaction and conclude from the data clinically applicable consequences.
Gáti
Agnes
A
PTE AOK Pszichiátriai és Pszichoterápiás Klinika, Pecs, Hungary. agnes.gati@aok.pte.hu
Abrahám
Ildikó
I
D000856:Anorexia Nervosa / Q000235:genetics; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics; D052018:Bulimia Nervosa / Q000235:genetics; D005190:Family; D001068:Feeding and Eating Disorders / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D054439:Ghrelin / Q000235:genetics; D006801:Humans; D020738:Leptin / Q000235:genetics; D053486:Melanocortins / Q000235:genetics; D009478:Neuropeptide Y / Q000235:genetics; D044105:Receptor, Melanocortin, Type 4 / Q000235:genetics; D050638:Receptors, Dopamine D4 / Q000235:genetics; D011960:Receptors, Estrogen / Q000235:genetics; D011985:Receptors, Serotonin / Q000235:genetics; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics; D012931:Social Environment; D018433:Twin Studies as Topic
D019208:Brain-Derived Neurotrophic Factor; C493599:DRD4 protein, human; D054439:Ghrelin; D020738:Leptin; D053486:Melanocortins; D009478:Neuropeptide Y; D044105:Receptor, Melanocortin, Type 4; D011960:Receptors, Estrogen; D011985:Receptors, Serotonin; C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins; D050638:Receptors, Dopamine D4