title: Normalized power transmission between ABP and ICP in TBI.
abstract: A new approach to study the pulse transmission between the cerebrovascular bed and the intracranial space is presented. In the proposed approach, the normalized power transmission between ABP and ICP has got the main attention rather than the actual power transmission. Evaluating the gain of the proposed transfer function at any single frequency can reveal how the percentage of contribution of that specific frequency component has been changed through the cerebrospinal system. The gain of the new transfer function at the fundamental cardiac frequency was utilized to evaluate the state of the brain in three TBI patients. Results were assessed using the reference evaluations achieved by a novel CT scan-based scoring scheme. In all three study cases, the gain of the transfer function showed a good capability to follow the trend of the CT scores and describe the brain state. Comparing the new transfer function with the traditional one and also the index of compensatory reserve, the proposed transfer function was found more informative about the state of the brain in the patients under study.
authors: Department of Signals and Systems, Signal Processing, Chalmers University of Technology, Sweden. shahsava@chalmers.se
authors: S
authors: S
authors: Shahsavari
authors: T
authors: T
authors: Hallen
authors: T
authors: T
authors: McKelvey
authors: C
authors: C
authors: Ritzen
authors: B
authors: B
authors: Rydenhag
mesh_terms: D000465:Algorithms; D001794:Blood Pressure / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology*; D005583:Fourier Analysis; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*