Steric decompression of picket-strapped porphyrins for the synthesis of side-differentiated chelates.
A general method to synthesize various alphabeta alphabeta bis-strapped porphyrins, with a different functionalization on each side of the macrocycle, is described. The resulting new chelates may find applications as analogues of heme protein active sites, bifunctional chelates, or specific bis-chelating molecules with potential medical utility.
Balieu
S
S
Université de Rennes1-Sciences Chimiques de Rennes, UMR CNRS 6226 (I.C.M.V.), 35042 Rennes, France.
Hijazi
I
I
Motreff
N
N
Lachaud
F
F
Even-Hernandez
P
P
Boitrel
B
B
D001665:Binding Sites; D002614:Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry; D006420:Hemeproteins / Q000187:drug effects; D008665:Metalloporphyrins / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
D002614:Chelating Agents; D006420:Hemeproteins; D008665:Metalloporphyrins