Drug-related cardiac pathology.
Many commonly used drugs, with each causing changes that may be potentially lethal, can adversely affect the function of the heart. In addition some drugs have synergistic effects that can also damage cardiovascular tissues. The drug-related cardiotoxic effects of antineoplastic agents, psychotropic medications, heavy metals, substances of abuse, promotility agents, antihistamines, antimicrobials and antiarrhythmic agents are discussed. Hypersensitivity myocarditis is also discussed.
Butany
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J
Department of Pathology, Toronto General Hospital/University Health Network, Toronto, Ontario M5G 2C4, Canada. Jagdish.butany@uhn.on.ca
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D000970:Antineoplastic Agents / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D006331:Heart Diseases / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D019216:Metals, Heavy / Q000009:adverse effects; D011619:Psychotropic Drugs / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000150:complications
D000970:Antineoplastic Agents; D019216:Metals, Heavy; D011619:Psychotropic Drugs