title: Use of a chitosan-based hemostatic dressing in dacryocystorhinostomy.
abstract: OBJECTIVE
  To evaluate the use of a chitosan-based hemostatic dressing (CBHD) (ChitoFlex, HemCon Medical Technologies Inc., Portland, OR, U.S.A.) as an effective adjunct for hemostasis in dacryocystorhinostomy surgery and compare its effectiveness to collagen absorbable hemostat (CAH) (Insat, Johnson & Johnson Gateway, New Brunswick, NJ, U.S.A.).
  
  
  METHODS
  Retrospective, comparative case series. Thirty-five external or endoscopic dacryocystorhinostomy (DCR) and conjuctival dacryocystorhinostomy (CDCR) procedures were performed on 26 patients using the CBHD from May through October 2007. Thirty-five external or endoscopic DCR or CDCR procedures were performed on 27 patients using CAH from February through May 2007. Collection of patient data in the group treated with CBHD included the types of cases performed, surgical outcome, complications, adverse reactions, and telephone follow-up survey of symptomatic results. Collection of patient data in the group treated with CAH primarily focused on the types of cases performed and postoperative bleeding. The main outcome measures were postoperative bleeding and need for anterior nasal packing.
  
  
  RESULTS
  Postoperative bleeding occurred in 2 cases in the group treated with CBHD and in 12 cases in the CAH group.
  
  
  CONCLUSIONS
  The study demonstrates the effectiveness and safety of CBHD as a hemostatic agent in DCR and CDCR and as a promising alternative to CAH.
authors: Oculofacial Plastic and Reconstructive Surgery, Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon 97239, USA.
authors: Roger A
authors: RA
authors: Dailey
authors: Mauricio R
authors: MR
authors: Chavez
authors: Dongseok
authors: D
authors: Choi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D048271:Chitosan / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use; D003608:Dacryocystorhinostomy / Q000379:methods*; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009301:Nasolacrimal Duct / Q000601:surgery; D009779:Occlusive Dressings; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D012189:Retrospective Studies; D015503:Surgical Sponges; D055815:Young Adult
chemical_list: D006490:Hemostatics; D003094:Collagen; D048271:Chitosan