title: Design and evaluation of a hybrid passive and active gravity neutral orthosis (GNO).
abstract: Neuromuscular diseases (NMD), including Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), result in progressive muscular weakness that often leaves patients functionally dependent on caregivers for many activities of daily living (ADL) such as eating, bathing, grooming (touching the face and head), reaching (grabbing for objects), and dressing. In severe cases, patients are unable to perform even the simplest of activities from exploring their 3D space to touching their own face. The ability to move and initiate age appropriate tasks, such as playing and exploration, are considered to be of vital importance to both their physical and cognitive development. Therefore, to improve quality of life and reduce dependence on caregivers in children and young adults with NMD, we designed, built and evaluated an assistive, active orthosis to support arm function. The goal of this project is the development and evaluation of a mechanical arm orthosis to both encourage and assist functional arm movement while providing the user a sense of independence and control over one's own body.
authors: Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 USA.
authors: Benjamin
authors: B
authors: Koo
authors: Jacqueline
authors: J
authors: Montes
authors: Viktor
authors: V
authors: Gamarnik
authors: Keith
authors: K
authors: Yeager
authors: Jonathan
authors: J
authors: Marra
authors: Sally
authors: S
authors: Dunaway
authors: Megan
authors: M
authors: Montgomery
authors: Darryl C
authors: DC
authors: De Vivo
authors: Nancy
authors: N
authors: Strauss
authors: Elisa
authors: E
authors: Konofagou
authors: Petra
authors: P
authors: Kaufmann
authors: Barclay
authors: B
authors: Morrison
mesh_terms: D000203:Activities of Daily Living; D006112:Gravitation; D006801:Humans; D009134:Muscular Atrophy, Spinal / Q000503:physiopathology / Q000628:therapy; D009136:Muscular Dystrophies / Q000503:physiopathology / Q000628:therapy; D009989:Orthotic Devices