title: Hepatitis C treatment concomitant to chemotherapy as "salvage" therapy in children with hematologic malignancies.
abstract: In patients with malignancies, chronic hepatitis C reactivation or severe flare is uncommon and antiviral treatment is deferred mainly due to underlying bone marrow and immune suppression. We report the use of antiviral treatment concomitantly to chemotherapy in 3 children with hematologic malignancies, chronic hepatitis C, and significant liver dysfunction.
authors: Second Department of Pediatrics, University of Athens Medical School, P & A Kyriakou Children's Hospital, Goudi, Athens, Greece. vpapaev@med.uoa.gr
authors: Vassiliki
authors: V
authors: Papaevangelou
authors: Marianna
authors: M
authors: Varsami
authors: Vassilios
authors: V
authors: Papadakis
authors: Aglaia
authors: A
authors: Zellos
authors: Agapi
authors: A
authors: Parcharidou
authors: Sophia
authors: S
authors: Papargyri
authors: Ourania
authors: O
authors: Karentzou
authors: Nina
authors: N
authors: Manolaki
authors: Eleftheria
authors: E
authors: Roma
authors: Sophia
authors: S
authors: Polychronopoulou
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D019337:Hematologic Neoplasms / Q000150:complications* / Q000188:drug therapy*; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D016879:Salvage Therapy / Q000379:methods*; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D000410:Alanine Transaminase