[Determination of the concentration of C-reactive protein, oligopeptides and lactoferrin of blood as a method of early diagnosis of mesenchymal sepsis].
The investigation of results of treatment included the observation of 2250 patients with pyo-necrotic diseases of soft tissues. For the early diagnosis of sepsis the indices of C-reactive protein, oligopeptides and lactoferrin of blood were used. In the presence of one or more symptoms of the systemic inflammatory reaction the level of the indices was increased from 1.1-3.1 up to 4-7 times depending on the degree of the systemic response severity. When the inflammatory process was local the data of the markers remain normal. These markers allow the confirmation of the clinical diagnosis of sepsis, assessment of the degree of the systemic inflammatory reaction and prognosis of the disease.
Barkhatova
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D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D007781:Lactoferrin / Q000097:blood*; D009842:Oligopeptides / Q000097:blood*; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D018805:Sepsis / Q000097:blood* / Q000175:diagnosis; D012720:Severity of Illness Index; D013997:Time Factors
D015415:Biomarkers; D009842:Oligopeptides; D002097:C-Reactive Protein; D007781:Lactoferrin