[Prevalence of hepatitis G, B and C virus infections among positive HIV population in a Tunisian Hospital, La Rabta, Tunis].
OBJECTIVE
The viral hepatitis G and HIV coinfection has been largely treated in the litterature. The aim of this study was to evaluate the coinfection rate in our hospital and to compare the HGV frequency to other hepatitis viruses (B and C) in positive HIV subjects at the Rabta hospital in Tunis, Tunisia.


METHODS
The studied population included 125 HIV positives patients from the infectious diseases unit. The detection of the hepatitis B and C was carried out using serologic test (Elisa-Biorad). The molecular detection of the HGV was realized by reverse transcriptase polymerase chain reaction (RT-PCR).


RESULTS
The prevalence of serological markers of hepatitis B (antibodies and/or antigens) and C (antibodies) was respectively 32.25% and 26.4%. HGV RNA was detected in 36.8% of the studied population. The unprotected intercourse was the predominant risk factor of the HGV contamination. Among the HGV (+) patients, 28.2% were carriers of the hepatitis C antibodies (anti-HCV).


CONCLUSIONS
This work was the first study enabling to assess the coinfection rate of viral hepatitis B, C and G with HIV patients (+) in Rabta Hospital. The regular screening of HGV is recommended regarding its high frequency and the possibility of its pathogenic role.
Maaref
F
F
Laboratoire de Microbiologie, CHU La Rabta, 13 Rue Jebberi, 1007 Tunis, Tunisie. maaref_farah@yahoo.fr
Kilani
B
B
Ammari
L
L
Ben Othman
A
A
Zribi
M
M
Fendri
C
C
Masmoudi
A
A
D000328:Adult; D060085:Coinfection; D005260:Female; D018178:Flaviviridae Infections / Q000150:complications / Q000453:epidemiology* / Q000635:transmission; D029407:GB virus C / Q000235:genetics; D006679:HIV Seropositivity / Q000150:complications*; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D006526:Hepatitis C / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000453:epidemiology* / Q000635:transmission; D006761:Hospitals; D006801:Humans; D008297:Male; D012367:RNA, Viral / Q000032:analysis; D012698:Serologic Tests; D012749:Sexually Transmitted Diseases; D014416:Tunisia / Q000453:epidemiology
D012367:RNA, Viral