o-Nitrophenyl sulfoxides: efficient precursors for the mild preparation of alkenes.
o-Nitrophenyl sulfoxides were found to be efficient synthetic precursors of various alkene types. The elimination occurs in toluene and NaOAc to generate substituted and terminal alkenes. Alkene products were easily obtained in high purity due to the simultaneous precipitation of the o-nitrophenyl sulfenic acid byproduct. The methods described have practical applications for the preparation of unsaturated compounds under mild, thermolytic conditions.
Lu
Xiao
X
Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia 30602-2352, USA.
Long
Timothy E
TE
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D013454:Sulfoxides / Q000737:chemistry*
D000475:Alkenes; D009574:Nitro Compounds; D013454:Sulfoxides