Screening: is breast cancer overdiagnosed?
Jørgensen and Gøtzsche quantified the degree of overdiagnosis of breast cancer in five publicly organized mammography screening programs in different parts of the world. overall, they estimated a total degree of breast cancer (including carcinoma in situ) overdiagnosis of 52%, while overdiagnosis for invasive breast cancer was 35%, a finding with potential implications for both clinical practice and public health.
Veronesi
Andrea
A
Division of Medical Oncology C, Epidemiology Unit, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy. averonesi@cro.it
Serraino
Diego
D
D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D003951:Diagnostic Errors; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008327:Mammography / Q000592:standards*