title: Flow visualization of three-dimensionality inside the 12 cc Penn State pulsatile pediatric ventricular assist device.
abstract: In order to aid the ongoing concern of limited organ availability for pediatric heart transplants, Penn State has continued development of a pulsatile Pediatric Ventricular Assist Device (PVAD). Initial studies of the PVAD observed an increase in thrombus formation due to differences in flow field physics when compared to adult sized devices, which included a higher degree of three-dimensionality. This unique flow field brings into question the use of 2D planar particle image velocimetry (PIV) as a flow visualization technique, however the small size and high curvature of the PVAD make other tools such as stereoscopic PIV impractical. In order to test the reliability of the 2D results, we perform a pseudo-3D PIV study using planes both parallel and normal to the diaphragm employing a mock circulatory loop containing a viscoelastic fluid that mimics 40% hematocrit blood. We find that while the third component of velocity is extremely helpful to a physical understanding of the flow, particularly of the diastolic jet and the development of a desired rotational pattern, the flow data taken parallel to the diaphragm is sufficient to describe the wall shear rates, a critical aspect to the study of thrombosis and design of such pumps.
authors: Department of Bioengineering, The Pennsylvania State University, 205 Hallowell Building, University Park, PA 16802, USA.
authors: Breigh N
authors: BN
authors: Roszelle
authors: Steven
authors: S
authors: Deutsch
authors: Keefe B
authors: KB
authors: Manning
mesh_terms: D040761:Biomimetic Materials; D001783:Blood Flow Velocity; D019544:Equipment Failure Analysis / Q000295:instrumentation* / Q000379:methods; D006353:Heart-Assist Devices; D006801:Humans; D008955:Models, Cardiovascular; D010372:Pediatrics / Q000295:instrumentation*; D011474:Prosthesis Design; D012212:Rheology / Q000295:instrumentation*