Acetate permease (ActP) Is responsible for tellurite (TeO32-) uptake and resistance in cells of the facultative phototroph Rhodobacter capsulatus.
The highly toxic oxyanion tellurite has to enter the cytoplasm of microbial cells in order to fully express its toxicity. Here we show that in the phototroph Rhodobacter capsulatus, tellurite exploits acetate permease (ActP) to get into the cytoplasm and that the levels of resistance and uptake are linked.
Borghese
Roberto
R
Department of Biology, General Microbiology Unit, University of Bologna, Bologna, Italy. roberto.borghese@unibo.it
Zannoni
Davide
D
D000085:Acetates / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000235:genetics; D000693:Anaerobiosis / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics*; D001692:Biological Transport; D002463:Cell Membrane Permeability / Q000235:genetics; D015169:Colony Count, Microbial; D004926:Escherichia coli / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D017136:Ion Transport; D008027:Light; D026901:Membrane Transport Proteins / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D018384:Oxidative Stress / Q000235:genetics; D010100:Oxygen; D016354:Rhodobacter capsulatus / Q000235:genetics*; D013691:Tellurium / Q000378:metabolism*
D000085:Acetates; D001426:Bacterial Proteins; D026901:Membrane Transport Proteins; D000251:Adenosine Triphosphatases; C026660:tellurous acid; D013691:Tellurium; D010100:Oxygen