title: Dearomatization reactions of N-heterocycles mediated by group 3 complexes.
abstract: Group 3 (Sc, Y, Lu, La) benzyl complexes supported by a ferrocene diamide ligand are reactive toward aromatic N-heterocycles by mediating their coupling and, in a few cases, the cleavage of their C-N bonds. When these complexes reacted with 2,2'-bipyridine or isoquinoline, they facilitated the alkyl migration of the benzyl ligand onto the pyridine ring, a process accompanied by the dearomatization of the N-heterocycle. The products of the alkyl-transfer reactions act as hydrogen donors in the presence of aromatic N-heterocycles, ketones, and azobenzene. Experimental and computational studies suggest that the hydrogen transfer takes place through a concerted mechanism. An interesting disproportionation reaction of the dearomatized, alkyl-substituted isoquinoline complexes is also reported.
authors: Department of Chemistry & Biochemistry, University of California, Los Angeles, California 90095, USA.
authors: Kevin L
authors: KL
authors: Miller
authors: Bryan N
authors: BN
authors: Williams
authors: Diego
authors: D
authors: Benitez
authors: Colin T
authors: CT
authors: Carver
authors: Kevin R
authors: KR
authors: Ogilby
authors: Ekaterina
authors: E
authors: Tkatchouk
authors: William A
authors: WA
authors: Goddard
authors: Paula L
authors: PL
authors: Diaconescu