[Observation on therapeutic effect of acupuncture for treatment of patients with nonalcoholic steatohepatitis].
OBJECTIVE
To observe the therapeutic effect of acupuncture for treatment of patients with nonalcoholic steatohepatitis.


METHODS
Ninety-eight cases were randomly divided into an acupuncture group (n= 50) and a medicine group (n=48). The acupuncture group was treated with acupuncture at Shenshu (BL 23), Guanyuan (CV 4), Taixi (KI 3), Sanyinjiao (SP 6), etc.; the medicine group was treated with oral administration of Polyene Phosphatidylcholine Capsules. They were treated for 12 weeks. The changes of clinical symptoms, serum enzyme, blood fat and abdominal CT performance were compared between the two groups before and after treatment.


RESULTS
After treatment, alanine aminotransferase (ALT), aspartate aminotransferase (AST), galactosylhydroxylysyl glucosyltransferase (GGT), triglyeride (TG) and total cholesterol (TC) significantly decreased in the acupuncture group (all P<0.01); ALT, AST and GGT significantly decreased in the medicine group (all P<0.01), and there were no significant differences in changes of TG and TC in the medicine group (both P>0.05). After treatment, CT image showed there was significant improvement of liver injury in both groups (both P<0.01), and the improvement of liver injury in the acupuncture group was superior to that in the medicine group (P<0.01).


CONCLUSIONS
Acupuncture has a significant therapeutic effect on nonalcoholic steatohepatitis.
Meng
Sheng-xi
SX
Department of Digestology, The First Affiliated Hospital of Henan College of TCM, Zhengzhou, China. mengshengxi@yahoo.cn
D015670:Acupuncture Therapy; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D002784:Cholesterol / Q000097:blood; D005234:Fatty Liver / Q000097:blood / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase