[Chemical constituents of Lobelia chinensis].
OBJECTIVE
To study the chemical constituents from Lobelia chinensis.


METHODS
The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data.


RESULTS
Seven compounds were isolated from the titled plant. They were identified as 5-hydroxy-4'-methoxyflavone-7-O-rutinoside (1), n-butyl-O-beta-D-fructopyranoside (2), 5,7-dimethoxycoumarin (3), cirsiumaldehyde (4), diosmetin (5), 5-hydroxymethyl-2-furancarboxaldehyde (6), and 6-hydroxy-7-methoxycoumarin (7).


CONCLUSIONS
Compounds 2-4, 6, and 7 were obtained from the titled plant for the first time.
Han
Jinglan
J
Key Laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhang
Fengling
F
Li
Zhihong
Z
Du
Guanhua
G
Qin
Hailin
H
D003374:Coumarins / Q000032:analysis; D005663:Furans / Q000032:analysis; D029746:Lobelia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification
C438025:5-hydroxymethyl-2-furancarboxaldehyde; D003374:Coumarins; D005663:Furans; D010936:Plant Extracts; C037446:5,7-dimethoxycoumarin