Surgical treatment of primary intracranial myxoma in a child following radiotherapy: case report and review of the literature.
BACKGROUND
Myxomas are benign tumors of the mesenchymal origin and account for about half of the benign cardiac tumors. Occasionally, they occur at other locations, but the intracranial manifestation of a myxoma is exceptionally rare. As a secondary neoplasia following radiotherapy, myxoma has only been reported once in the literature.


METHODS
A 12-year-old girl, who was previously treated for a medulloblastoma, was diagnosed with a new lesion at the left transverse sinus in the follow-up magnetic resonance imaging (MRI). Indication for surgery was made and complete removal could be achieved.


CONCLUSIONS
Histological examination revealed a myxoma. Further staging showed no other manifestation of the myxoma. The close relation to the radiation field of the posterior fossa makes it highly suggestive that the myxoma developed as a secondary neoplasia induced by radiotherapy. Treatment philosophy for this benign tumor entity is a completed resection of the lesion with regular follow-up MRI.
Mueller
Oliver M
OM
Department of Neurosurgery, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany. Oliver.mueller@uk-essen.de
van de Nes
Johannes A P
JA
Wieland
Regina
R
Schoch
Beate
B
Sure
Ulrich
U
D001921:Brain / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000473:pathology / Q000532:radiotherapy*; D009232:Myxoma / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D011859:Radiography; D013997:Time Factors