title: [Reducing the frequency of fresh frozen donor plasma transfusion on the basis of the results of thromboelastographic study in neurosurgical patients with intraoperative blood loss].
abstract: The paper gives the results of a study of the time course of changes in the major laboratorily determined hemostatic parameters, as well as the main characteristics of a thromboelastographic curve in 95 neurosurgical patients who developed significant intraoperative blood loss at surgery. The patients were divided into 2 comparable groups: 1) a decision on fresh frozen donor plasma transfusion was taken only on the basis of laboratory parameters; 2) this was done on the basis of thromboelastographic data. In Group 2, the frequency of fresh frozen donor plasma transfusion proved to be 4 times less than that in Group 1. The use of thromboelastography to evaluate the hemostatic system during operations with a significant blood loss volume permits a reduction in the frequency of fresh frozen donor plasma, without deteriorating the results of treatment.
authors: L A
authors: LA
authors: Israelian
authors: V V
authors: VV
authors: Gromova
authors: A Iu
authors: AIu
authors: Lubnin
mesh_terms: D000328:Adult; D000465:Algorithms; D001782:Blood Donors; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D005260:Female; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D010949:Plasma; D010951:Plasma Exchange / Q000706:statistics & numerical data; D010952:Plasma Substitutes / Q000008:administration & dosage; D011446:Prospective Studies; D015173:Supratentorial Neoplasms / Q000601:surgery; D013916:Thrombelastography / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D010952:Plasma Substitutes