Adult T-cell leukemia-lymphoma associated with follicular mucinosis.
Follicular mucinosis (alopecia mucinosa) is often associated with malignancies including mycosis fungoides and Sézary syndrome, but not adult T-cell leukemia-lymphoma (ATLL). We report a 49-year-old male patient who had pruritic follicular papules and erythemas clinically, and follicular and perifollicular infiltrates and follicular mucin deposition histopathologically. The patient showed 11% of flower-shaped atypical lymphocytes in blood examination and positive human T-cell leukemia virus type 1 antibody in serology, consistent with the chronic type of ATLL. This case seems to be a very rare association of follicular mucinosis and chronic ATLL, suggesting that malignant T cells may have a feature of folliculotropism as well as epidermotropism.
Wada
Tamae
T
Department of Dermatology, Kinki University School of Medicine, Osaka, Japan.
Yoshinaga
Eiji
E
Oiso
Naoki
N
Kawara
Shigeru
S
Kawada
Akira
A
Kozuka
Takehito
T
D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications* / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged; D000507:Mucinosis, Follicular / Q000150:complications* / Q000473:pathology
D004279:DNA, Viral