title: Quantitative analysis of heart sounds and systolic heart murmurs using wavelet transform and AR modeling.
abstract: A quantitative approach integrating AR modeling and wavelet transform is presented in this paper to analyze the digitized phonocardiogram. The recognition of the first and the second heart sounds (S(1) and S(2)) were facilitated with wavelet transform without referring to the QRS waveform. We found that the Daubechies wavelet is most effective in identifying S(1) and S(2). In addition, the boundaries of S(1), S(2), and the onset and duration of the systolic murmur thus identified within the systole could be marked using the wavelet-filtered signal's strength. Furthermore, quantitative measures derived from a 2(nd) order AR model were used to delineate the configuration and pitch of the systolic murmur found within through piecewise segmentation. The proposed approach was tested and proved effective in delineating a set of clinically diagnosed systolic murmurs. The suggested AR and wavelet transform combined approach can be generalized with minor adjustments to delineate diastolic murmurs as well.
authors: Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA. james.ning@dartmouth.edu
authors: James
authors: J
authors: Ning
authors: Nikolay
authors: N
authors: Atanasov
authors: Taikang
authors: T
authors: Ning
mesh_terms: D000465:Algorithms; D003627:Data Interpretation, Statistical; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006326:Heart Auscultation / Q000379:methods*; D006337:Heart Murmurs / Q000175:diagnosis*; D006801:Humans; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity