Management of old world cutaneous leishmaniasis in refugee children.
The optimal treatment of cutaneous leishmaniasis is controversial. We report our experience managing Old World cutaneous leishmaniasis in a pediatric refugee clinic. Conventional amphotericin B therapy caused reversible renal failure in 2 of 3 children treated. The choice of treatment for cutaneous leishmaniasis needs to balance the risks of treatment against the likely cosmetic benefits of therapy.
Crogan
Joanne
J
Department of Immunology and Infectious Diseases, Refugee Clinic, The Children's Hospital at Westmead, Westmead, NSW, Australia.
Gunasekera
Hasantha
H
Wood
Nicholas
N
Sheikh
Mohamud
M
Isaacs
David
D
D000666:Amphotericin B / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D001315:Australia; D002648:Child; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000469:parasitology; D008081:Liposomes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D012036:Refugees; D051437:Renal Insufficiency / Q000139:chemically induced*; D016896:Treatment Outcome
D000935:Antifungal Agents; D008081:Liposomes; D000666:Amphotericin B; D015725:Fluconazole