Intralesional corticosteroid injection for central giant cell granuloma: an alternative treatment for children.
The purpose of the present article was to report a case of central giant cell granuloma (CGCG) associated with intralesional corticosteroid injections. Although benign, the CGCG may be locally aggressive, causing extensive bone destruction, tooth displacement, and root resorption. The common therapy is surgery, which may result in important facial deformity and loss of teeth or dental germs. In this article, an 8-year-old girl who presented with maxillary CGCG was treated with a solution of equal parts of triamcinolone actinide (10 mg/ml) and 0.5% bupivacaine injected into the lesion for a period of 11 weeks. The osseous neoformation was gradual. After 6-years follow-up, clinical and radiographic success of treatment were observed. Based on our results and the literature available, the administration of intralesional corticosteroid injections is an alternative in CGCG treatment, especially in children.
Wendt
Flavia Prietsh
FP
Dentistry School of Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Torriani
Marcos Antônio
MA
Gomes
Ana Paula Neutzling
AP
de Araujo
Lenita Maria Aver
LM
Torriani
Dione Dias
DD
D000779:Anesthetics, Local / Q000008:administration & dosage; D001861:Bone Regeneration; D002045:Bupivacaine / Q000008:administration & dosage; D002648:Child; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage*; D006101:Granuloma, Giant Cell / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional; D008439:Maxillary Diseases / Q000188:drug therapy*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
D000779:Anesthetics, Local; D004338:Drug Combinations; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D002045:Bupivacaine