title: Outcome after bariatric surgery in two adolescents with hypothalamic obesity following treatment of craniopharyngioma.
abstract: Treatment of craniopharyngioma (CP) in childhood can lead to severe, debilitating obesity with devastating medical and psychological outcomes. Despite sustained nutritional and exercise-oriented interventions, no efficacious medical option is available for hypothalamic obesity. We describe two adolescents who developed morbid obesity and significant comorbidities following diagnosis and treatment of CP, in whom bariatric surgery was achieved, illustrating a novel approach for symptomatic hypothalamic obesity, as well as positive and negative outcomes.
authors: Department of Pediatrics, Divisions of Endocrinology, CHU Sainte-Justine, Université de Montréal, Montreal, PQ, Canada. diane.rottembourg@free.fr
authors: Diane
authors: D
authors: Rottembourg
authors: Clodagh S
authors: CS
authors: O'Gorman
authors: Stacey
authors: S
authors: Urbach
authors: Pierre Y
authors: PY
authors: Garneau
authors: Jacob C
authors: JC
authors: Langer
authors: Guy
authors: G
authors: Van Vliet
authors: Jill
authors: J
authors: Hamilton
authors: Céline
authors: C
authors: Huot
mesh_terms: D000293:Adolescent; D050110:Bariatric Surgery / Q000009:adverse effects / Q000534:rehabilitation; D002648:Child; D003397:Craniopharyngioma / Q000628:therapy*; D005260:Female; D006801:Humans; D007027:Hypothalamic Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008297:Male; D009765:Obesity / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000628:therapy*; D011379:Prognosis; D016896:Treatment Outcome