Primary antiphospholipid syndrome with recurrent coronary thrombosis, acute pulmonary thromboembolism and intracerebral hematoma.
We present a young patient with myocardial infarction who had recurrent coronary thrombosis, in-stent thrombosis, and a major pulmonary arterial thromboembolism due to primary antiphospholipid syndrome. He also developed multiple intracerebral hematomas following anticoagulation therapy and thrombolysis. We describe this rare case of primary antiphospholipid syndrome presenting with varied arterial abnormalities along with hemorrhage and highlight the need for caution while treating them with anticoagulants and thrombolytics.
Prashanth
Panduranga
P
Department of Cardiology, Royal Hospital, Muscat, Oman. prashanthp_69@yahoo.co.in
Mukhaini
Mohammed Khamis
MK
D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications*; D003328:Coronary Thrombosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use; D006406:Hematoma / Q000139:chemically induced / Q000175:diagnosis*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000139:chemically induced / Q000175:diagnosis*; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D016896:Treatment Outcome
D000925:Anticoagulants; D005343:Fibrinolytic Agents