title: Exercise-induced functional mitral regurgitation in heart failure and preserved ejection fraction: a new entity.
abstract: We report here the worsening of functional mitral regurgitation (MR) during dynamic exercise Doppler echocardiography in four female patients with heart failure and preserved ejection fraction. MR worsened concomitantly to an increase in systolic mitral tenting area and in E/E(a) ratio, whereas local left ventricular (LV) remodelling was not substantially aggravated by exercise. We accordingly suggest that exercise-induced increase in LV filling or left atrial pressure that in turn leads to increase in mitral tenting area worsens functional MR during exercise.
authors: Centre Hospitalier Régional et Universitaire de Lille, Service d'explorations fonctionnelles cardiovasculaires, Lille, France.
authors: Sylvestre
authors: S
authors: Maréchaux
authors: Julia
authors: J
authors: Terrade
authors: Frédéric
authors: F
authors: Biausque
authors: Yann
authors: Y
authors: Lefetz
authors: Régis
authors: R
authors: Deturck
authors: Philippe
authors: P
authors: Asseman
authors: Thierry H
authors: TH
authors: Le Jemtel
authors: Pierre V
authors: PV
authors: Ennezat
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015150:Echocardiography, Doppler; D015444:Exercise; D017079:Exercise Tolerance; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D013318:Stroke Volume