Journeys through the Golgi--taking stock in a new era.
The Golgi apparatus is essential for protein sorting and transport. Many researchers have long been fascinated with the form and function of this organelle. Yet, despite decades of scrutiny, the mechanisms by which proteins are transported across the Golgi remain controversial. At a recent meeting, many prominent Golgi researchers assembled to critically evaluate the core issues in the field. This report presents the outcome of their discussions and highlights the key open questions that will help guide the field into a new era.
Emr
Scott
S
Department of Cell and Developmental Biology, CRG-Centre de Regulació Genòmica, Institutcio Catalana de Recerca I Estudis Avancats, 88 08003 Barcelona, Spain.
Glick
Benjamin S
BS
Linstedt
Adam D
AD
Lippincott-Schwartz
Jennifer
J
Luini
Alberto
A
Malhotra
Vivek
V
Marsh
Brad J
BJ
Nakano
Akihiko
A
Pfeffer
Suzanne R
SR
Rabouille
Catherine
C
Rothman
James E
JE
Warren
Graham
G
Wieland
Felix T
FT
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D003226:Congresses as Topic; D006056:Golgi Apparatus / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D007425:Intracellular Membranes / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D021381:Protein Transport / Q000502:physiology; D040901:Proteomics / Q000379:methods / Q000639:trends*