title: [Study on sugarcane alkane alcohol to quail hyperlipidemia and atherosclerosis model].
abstract: OBJECTIVE
  To study on pharmacologic actions on quail hyperlipidemia and atherosclerosis model.
  
  
  METHODS
  To duplicate quail hyperlipidemia model by ectogenesis cholesterol and high fat forage, induce to atherosclerosis model, observe influence of sugarcane alkane alcohol to model animals' blood fat level, formation of atherosclerosis plaque, pathological changes of coronary vessels and vascular intimal.
  
  
  RESULTS
  TC, TG, LDL-C level in blood serum of quail hyperlipidemia markedly decreased after administered sugarcane alkane alcohol by dose of 30, 15, 7.5 mg x kg(-1), proliferation of aorta and brachiocephalic artery tunica intima foam cells was suppressed.
  
  
  CONCLUSIONS
  Sugarcane alkane alcohol has satisfactory pharmacologic actions on hyperlipidemia and atherosclerosis animal model by regulating blood fat.
authors: Guangdong Pharmaceutical University, Center Laboratory, Guangzhou 510006, China. shizhf@139.com
authors: Zhongfeng
authors: Z
authors: Shi
authors: Qixin
authors: Q
authors: Yan
authors: Jinhua
authors: J
authors: Zhao
authors: Guanghui
authors: G
authors: Yao
mesh_terms: D000473:Alkanes / Q000737:chemistry / Q000627:therapeutic use*; D000818:Animals; D050197:Atherosclerosis / Q000188:drug therapy*; D002784:Cholesterol / Q000097:blood; D004195:Disease Models, Animal; D000431:Ethanol / Q000737:chemistry / Q000627:therapeutic use*; D006949:Hyperlipidemias / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use; D011784:Quail; D011897:Random Allocation; D031786:Saccharum / Q000737:chemistry*
chemical_list: D000473:Alkanes; D010936:Plant Extracts; D000431:Ethanol; D002784:Cholesterol