[Choriocarcinoma with pulmonary metastasis: diagnosis and treatment].
BACKGROUND
Choriocarcinoma is a rare tumour which results from the anarchic proliferation of a gonadic or extra gonadic germinal cell.


METHODS
A 45 year old pre menopausal woman of African origin presented with a persistent cough and deterioration of general status. The chest X-ray revealed a cavitated mass of the right upper lobe. Other lesions were associated (liver, kidney and scalp). Choriocarcinoma, suspected in the presence of an elevated ssHCG without a gravid uterus, was confirmed by biopsy excision of a haemorrhagic cutaneous lesion of the scalp. Despite the poor prognosis methotrexate based chemotherapy resulted in control of the disease and a good remission.
Olezac
A-S
AS
Service de Pneumologie, Hôpital Saint-Antoine, Paris, France.
Papanikolaou
I
I
Bengrine-Lefevre
L
L
Chouaid
C
C
D000964:Antimetabolites, Antineoplastic; D001706:Biopsy; D002822:Choriocarcinoma / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000556:secondary; D031954:Choriocarcinoma, Non-gestational / Q000175:diagnosis; D006063:Chorionic Gonadotropin / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000556:secondary; D011379:Prognosis; D013902:Radiography, Thoracic; D012074:Remission Induction; D012535:Scalp / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D006063:Chorionic Gonadotropin; D008727:Methotrexate