title: [Piezoelectric property of novel biological piezoelectric ceramic HALNK and its effect on the functional expression of rat osteoblast cells].
abstract: OBJECTIVE
  To test the Piezoelectric property of novel biological piezoelectric ceramic HALNK and its effect on the proliferation and differentiation of rat osteoblast cells.
  
  
  METHODS
  The biological piezoelectric ceramic HALNK1/9 and HALNK5/5 were prepared by mixing Hydroxyapatite (HA) with lithium sodium potassium niobate (LNK) piezoelectric ceramic at a ratio of 1/9 and 5/5 (wt/wt), respectively. After poling treatment, the piezoelectric constants were measured. The osteoblast cells were then seeded on the surfaces of HALNK. The proliferation and differentiation activities of the osteoblast cells were evaluated by MTT assays, ALP activities and scanning electron microscopy examinations.
  
  
  RESULTS
  Cells grown on the surfaces of HALNK showed normal morphology, and had better proliferation and differentiation activities than the control. The growth of osteoblastic cells on the surface of HALNK1/9 was significantly better than others.
  
  
  CONCLUSIONS
  The surface of HALNK 1/9 possesses better piezoelectric property and osteogenesis potential than HALNK5/5.
authors: Department of General Surgery, Affiliation Hospital of Hebei University, Baoding, China.
authors: Peng
authors: P
authors: Wang
authors: Jin-Chao
authors: JC
authors: Zhang
authors: Xiao-Zhou
authors: XZ
authors: Zhang
authors: Zhi-Qin
authors: ZQ
authors: Liu
authors: Que-Ting
authors: QT
authors: Chen
authors: Jing
authors: J
authors: Sun
authors: Zhi-Qing
authors: ZQ
authors: Chen
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002454:Cell Differentiation / Q000528:radiation effects; D049109:Cell Proliferation / Q000528:radiation effects; D002516:Ceramics; D017886:Durapatite / Q000737:chemistry; D004581:Electronics / Q000295:instrumentation; D004735:Energy Transfer; D004867:Equipment Design; D008094:Lithium / Q000737:chemistry; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation*; D010006:Osteoblasts / Q000166:cytology* / Q000528:radiation effects; D051381:Rats; D012886:Skull / Q000166:cytology; D012964:Sodium / Q000737:chemistry
chemical_list: D017886:Durapatite; D008094:Lithium; D012964:Sodium