Iridium-catalyzed, regio- and enantioselective allylic substitution with aromatic and aliphatic sulfinates.
The iridium-catalyzed allylation of sodium sulfinate to form branched allylic sulfones is reported. The reactions between various sodium sulfinates and achiral allylic carbonates occur in good yields, with high selectivity for the branched isomer, and high enantioselectivities (up to 98% ee).
Ueda
Mitsuhiro
M
Department of Chemistry, University of Illinois, 600 South Matthews Avenue, Urbana, Illinois 61801, USA.
Hartwig
John F
JF
D000498:Allyl Compounds / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D013237:Stereoisomerism; D013441:Sulfinic Acids / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry
D000498:Allyl Compounds; D013441:Sulfinic Acids; D013450:Sulfones; D007495:Iridium