Deficits in the left inferior longitudinal fasciculus results in impairments in object naming.
The functional characteristics of the left inferior longitudinal fasciculus (ILF) remain unclear. The present study describes a case of a right-handed 74-year-old woman with a brain tumor who showed marked deterioration in object naming ability after invasion of the tumor into the medial region of the left posterior (middle and inferior) temporal lobe just beside the atrium of the lateral ventricle. Diffusion tensor imaging showed possible interruption of the left ILF after invasion of tumor at this site. By contrast, the left superior longitudinal fasciculus (SLF) remained intact after invasion of tumor, and the inferior fronto-occipital fasciculus (IFOF) was already disrupted prior to tumor invasion. These observations indicate that intact ILF function may be required for object naming ability.
Shinoura
Nobusada
N
Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan. shinoura@cick.jp
Suzuki
Yuichi
Y
Tsukada
Masanobu
M
Yoshida
Mizuho
M
Yamada
Ryozi
R
Tabei
Yusuke
Y
Saito
Kuniaki
K
Koizumi
Tomoyuki
T
Yagi
Kazuo
K
D000368:Aged; D000849:Anomia / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D001254:Astrocytoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D001931:Brain Mapping / Q000379:methods; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D056324:Diffusion Tensor Imaging / Q000379:methods; D004185:Disability Evaluation; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007802:Language; D007807:Language Tests; D008297:Male; D009361:Neoplasm Invasiveness / Q000473:pathology; D009413:Nerve Fibers, Myelinated / Q000502:physiology / Q000648:ultrastructure; D009434:Neural Pathways / Q000473:pathology* / Q000503:physiopathology; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures; D012016:Reference Values; D012086:Reoperation; D013702:Temporal Lobe / Q000473:pathology* / Q000503:physiopathology; D055815:Young Adult