title: Taste memory trace disruption by AP5 administration in basolateral amygdala.
abstract: N-methyl-D-aspartate receptor has been related to learning and memory processes. Its characteristics make it a key candidate in the modulation of associative processes at physiological level. Traditionally, the main efforts have been directed to show its role in excitatory conditioning. Nevertheless, the studies that have analyzed its implication in inhibitory learning are scarce. We present an experiment where a preexposure effect on the conditioning (latent inhibition) is disrupted by 2-amino-5-phosphonopentanoic acid administered in basolateral amygdala. This data shows interference on taste memory trace, and attenuation of the inhibition effect.
authors: Department of Experimental Psychology, Lab Neurociencia de la Conducta, University of Seville, Spain.
authors: Luis Miguel
authors: LM
authors: Traverso
authors: Esperanza
authors: E
authors: Quintero
authors: Juan Pedro
authors: JP
authors: Vargas
authors: Luis Gonzalo
authors: LG
authors: De la Casa
authors: Juan Carlos
authors: JC
authors: Lopez
mesh_terms: D015763:2-Amino-5-phosphonovalerate / Q000494:pharmacology*; D000679:Amygdala / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D000818:Animals; D001245:Association Learning / Q000187:drug effects / Q000502:physiology; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects*; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D005108:Extinction, Psychological / Q000187:drug effects / Q000502:physiology; D018698:Glutamic Acid / Q000378:metabolism; D007266:Inhibition, Psychological; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D008569:Memory Disorders / Q000139:chemically induced* / Q000378:metabolism / Q000503:physiopathology; D009483:Neuropsychological Tests; D051381:Rats; D017208:Rats, Wistar; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology; D055697:Taste Perception / Q000187:drug effects* / Q000502:physiology
chemical_list: D018691:Excitatory Amino Acid Antagonists; D018698:Glutamic Acid; D015763:2-Amino-5-phosphonovalerate