title: What contributes to driving ability in Parkinson's disease.
abstract: OBJECTIVE
  To determine the most significant clinical predictors that influence driving ability in Parkinson disease (PD).
  
  
  METHODS
  National-multi-centre, cross-sectional study covering PD outpatients. Clinical assessment was based on the following questionnaires: cognition (SCOPA-Cog); motor impairment and disabilities (SCOPA motor); depression/anxiety; sleep (SCOPA-Sleep); psychosis and severity/global impairment (HY and CISI-PD). Driving status data was obtained using a standardized questionnaire. Comparisons between drivers and ex-drivers were calculated using chi(2) and Student t-tests as appropriate. Multi-variate logistic regression analysis was performed to identify independent driving ability clinical predictors.
  
  
  RESULTS
  Compared with the drivers, the ex-drivers were older (p = 0.00005), had longer disease duration (p = 0.03), had more overall cognitive dysfunction (p = 0.004) and had greater motor impairment, as measured by the CISI (p = 0.02), HY stage (p = 0.034) and by the SCOPA-motor scale (p = 0.002) and difficulty in activities of daily life (p = 0.002). In the regression model analysis, aging and ADL impairment were the principal clinical predictors that differentiated drivers from ex-drivers.
  
  
  CONCLUSIONS
  Although overall driving impairment in PD is associated with advancing disease severity, driving ability seems to be more strongly influenced by age and ADL impairment. Multi-disciplinary teams are required to assess driving ability in patients with PD and develop rehabilitation measures for safer driving.
authors: Neurology Department, Hospital General Yague, Burgos, Spain. esthercub@wanadoo.es
authors: Esther
authors: E
authors: Cubo
authors: Pablo
authors: P
authors: Martinez Martin
authors: Miguel
authors: M
authors: Gonzalez
authors: Alberto
authors: A
authors: Bergareche
authors: Victor
authors: V
authors: Campos
authors: José Manuel
authors: JM
authors: Fernández
authors: María
authors: M
authors: Alvárez
authors: Angels
authors: A
authors: Bayes
mesh_terms: D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001259:Ataxia; D001334:Automobile Driving; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D010300:Parkinson Disease; D012720:Severity of Illness Index