title: Element contents in organs and tissues of Chinese adult men.
abstract: This study was undertaken to provide reference values for relevant parameters of Chinese Reference Man. Eighteen kinds of major organ or tissue samples, including muscle, rib, liver, and so on, were obtained from autopsies of 68 healthy adult men living in four areas of China with different dietary patterns (Hebei, Shanxi, Sichuan, Jiangxi or Jiangsu provinces, including Shanghai City) who had just encountered sudden deaths. At the same time, whole blood samples were collected from 10 volunteers living in each of these areas. The concentrations of 60 elements in these samples were detected by using inductively coupled plasma mass spectrometry (ICP-MS), inductively coupled plasma-atomic emission spectrometry (ICP-AES), neutron activation analysis (NAA), fluorometry (FL), graphite furnace atomic absorption spectrometry (GF-AAS) techniques and necessary quality control (QC) measures. Based on obtained concentrations and reference values of these organ or tissue weights for Chinese Reference Man, the elemental burdens in these organs or tissues were estimated. As a summary report of a series of research studies for Chinese Reference Man, which included three steps (from 1996 to 2006), the concentrations of 60 elements in 18 main organs or tissues were determined and their elemental burdens in the organs or tissues and whole body were estimated. Furthermore, the organ or tissue distributions of some important elements for radiation protection were discussed. These results may provide more reliable and better representative bases than before for establishing related reference values of Chinese Reference Man and revising current reference values of International Commission on Radiological Protection (ICRP) Reference Man. These basic data will also be very valuable for many other applications in radiation protection and other scientific fields.
authors: Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192 China. zhuhda@yahoo.com.cn
authors: Hongda
authors: H
authors: Zhu
authors: Neifen
authors: N
authors: Wang
authors: Yongbao
authors: Y
authors: Zhang
authors: Quan
authors: Q
authors: Wu
authors: Rusong
authors: R
authors: Chen
authors: Junquan
authors: J
authors: Gao
authors: Ping
authors: P
authors: Chang
authors: Qingfen
authors: Q
authors: Liu
authors: Tijiang
authors: T
authors: Fan
authors: Juan
authors: J
authors: Li
authors: Jixian
authors: J
authors: Wang
authors: Jingyu
authors: J
authors: Wang
mesh_terms: D000328:Adult; D044466:Asian People; D001822:Body Burden; D002681:China; D004032:Diet; D004602:Elements; D006801:Humans; D008297:Male; D011835:Radiation Protection / Q000706:statistics & numerical data; D012016:Reference Values; D014018:Tissue Distribution; D014131:Trace Elements / Q000032:analysis
chemical_list: D004602:Elements; D014131:Trace Elements