title: Assessment of fluorodeoxyglucose uptake by leiomyomas in relation to histopathologic subtype and the menstrual state.
abstract: OBJECTIVE
  The aim of this study was to assess fluorodeoxyglucose (FDG) uptake by leiomyomas in relation to histopathologic subtype and the menstrual state.
  
  
  METHODS
  We performed a retrospective study of 92 patients referred for uterine leiomyomas confirmed by histopathologic findings. On FDG-positron emission tomography, quantitative evaluation was performed using the mean values of the standardized uptake value (SUV) with reference to magnetic resonance imaging findings. Of the 92 patients, 56 had typical leiomyomas (41 premenopausal and 15 postmenopausal women), whereas 36 patients with subtype leiomyomas consisted of 21 premenopausal and 15 postmenopausal women.
  
  
  RESULTS
  Although no significant differences in SUV were observed between the typical and subtype leiomyomas, tumoral SUV was significantly higher in the premenopausal patients than in the postmenopausal patients. Uterine tumoral FDG uptake during the proliferative phase was also slightly lower than in the other menstrual phases.
  
  
  CONCLUSIONS
  The FDG uptake by leiomyomas in premenopausal women was greater than that in postmenopausal women.
authors: Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Yoshida-gun, Fukui, Japan. yyoshida@u-fukui.ac.jp
authors: Yoshio
authors: Y
authors: Yoshida
authors: Tetsuya
authors: T
authors: Tsujikawa
authors: Tetsuji
authors: T
authors: Kurokawa
authors: Takahiro
authors: T
authors: Tsuji
authors: Yoshiaki
authors: Y
authors: Imamura
authors: Yasuhisa
authors: Y
authors: Fujibayashi
authors: Hidehiko
authors: H
authors: Okazawa
authors: Fumikazu
authors: F
authors: Kotsuji
mesh_terms: D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D017698:Postmenopause; D017697:Premenopause; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18