Surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity.
OBJECTIVE
To report the surgical outcomes of endoscopic resection of adenocarcinomas of the Sinonasal cavity.


METHODS
Retrospective chart review of patients presenting with adenocarcinoma of the anterior skull base between 1998-2008. All patients who underwent wholly endoscopic resection were included in the study.


RESULTS
Twelve patients presented with adenocarcinoma involving the sino-nasal cavity. At diagnosis 6 patients were staged as a T2, 5 as a T3 and one as a T4. All of the patients had successful removal of the tumour entirely endoscopically. Three patients recurred: 2 locally and 1 with distant metastases. Overall, 11 patients are alive and free of disease and 1 patient dead of disease. We found an overall disease free survival rate and overall survival rate of 91.6%. The follow-up period ranged from 10 to 96 months with a median of 30 months.


CONCLUSIONS
Endoscopic management of adenocarcinoma of the sino-nasal cavity can be a viable treatment option to craniofacial resection. With the advancement in endoscopic equipment and surgeon skill, larger tumours may be managed wholly endoscopically.
Jardeleza
Camille
C
Department of Otolaryngology Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia.
Seiberling
Kristin
K
Floreani
Steve
S
Wormald
Peter-John
PJ
D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D004724:Endoscopy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000401:mortality / Q000601:surgery*; D010039:Otorhinolaryngologic Neoplasms / Q000601:surgery*; D019736:Prostheses and Implants; D013526:Surgical Mesh; D016896:Treatment Outcome