Preparation and chemical properties of 5-dialkylaminomethylhydantoins and 2-thio-analogues.
An efficient procedure for the preparation of 5-dialkylaminomethylhydantoins 3, which are easily obtained from cyclization of the corresponding urea derivatives 2 starting with beta-aminoalanines 1, is described. Methylenehydantoin and the corresponding 2-thio analogue (4a, 4b) were obtained from hydantoins 3a and 3b, respectively. Some new chemical properties of these hydantoin derivatives are reported.
Fujisaki
Fumiko
F
Fukuoka University, Nanakuma, Jonan-ku, Japan.
Shoji
Kaori
K
Sumoto
Kunihiro
K
D003500:Cyclization; D006827:Hydantoins / Q000737:chemistry*; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D015091:beta-Alanine / Q000031:analogs & derivatives / Q000737:chemistry*
D006827:Hydantoins; D013438:Sulfhydryl Compounds; D015091:beta-Alanine