What is the promise of new antiepileptic drugs in status epilepticus? Focus on brivaracetam, carisbamate, lacosamide, NS-1209, and topiramate.
Perucca
Emilio
E
University of Pavia and Clinical Trial Centre, Institute of Neurology IRCCS C Mondino Foundation, Italy. perucca@unipv.it
D000081:Acetamides / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology / Q000627:therapeutic use*; D002219:Carbamates / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D005632:Fructose / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D000078334:Lacosamide; D011758:Pyrroles / Q000494:pharmacology / Q000627:therapeutic use; D011760:Pyrrolidinones / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D018091:Receptors, AMPA / Q000037:antagonists & inhibitors; D013226:Status Epilepticus / Q000175:diagnosis / Q000188:drug therapy*; D044005:Tetrahydroisoquinolines / Q000494:pharmacology / Q000627:therapeutic use; D000077236:Topiramate; D016896:Treatment Outcome
D000081:Acetamides; D000927:Anticonvulsants; D002219:Carbamates; D011758:Pyrroles; D011760:Pyrrolidinones; D018091:Receptors, AMPA; C518914:S-2-O-carbamoyl-1-o-chlorophenyl-ethanol; C119326:SPD 502; D044005:Tetrahydroisoquinolines; D000077236:Topiramate; D005632:Fructose; D000078334:Lacosamide; C482793:brivaracetam