Meninges in cancer imaging.
Primary malignant tumours arising from the meninges are distinctly uncommon, and when they occur, they are usually sarcomas. In contrast, metastatic meningeal involvement is increasingly seen as advances in cancer therapy have changed the natural history of malignant disease and prolonged the life span of cancer patients. The meninges can either be infiltrated by contiguous extension of primary tumours of the central nervous system, paranasal sinuses and skull base origin or can be diffusely infiltrated from haematogenous dissemination from distant primary malignancies. Imaging in these patients provides crucial information in planning management. This article reviews the pertinent anatomy that underlies imaging findings, discusses the mechanism of meningeal metastasis and highlights different imaging patterns of meningeal carcinomatosis and the pitfalls.
Mahendru
G
G
National University Hospital, 119074, Singapore. gm18radio@yahoo.com
Chong
V
V
D002544:Cerebral Infarction / Q000175:diagnosis / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D017254:Leukemic Infiltration / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D055756:Meningeal Carcinomatosis / Q000175:diagnosis / Q000473:pathology / Q000556:secondary; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary; D008578:Meninges / Q000473:pathology* / Q000648:ultrastructure; D012509:Sarcoma / Q000473:pathology; D017287:Ventriculoperitoneal Shunt
D003287:Contrast Media