Monolayer formation of human osteoblastic cells on vertically aligned multiwalled carbon nanotube scaffolds.
Monolayer formation of SaOS-2 (human osteoblast-like cells) was observed on VACNT (vertically aligned multiwalled carbon nanotubes) scaffolds without purification or functionalization. The VACNT were produced by a microwave plasma chemical vapour deposition on titanium surfaces with nickel or iron as catalyst. Cell viability and morphology studies were evaluated by LDH (lactate dehydrogenase) release assay and SEM (scanning electron microscopy), respectively. The non-toxicity and the flat spreading with monolayer formation of the SaOs-2 on VACNT scaffolds surface indicate that they can be used for biomedical applications.
Lobo
Anderson O
AO
Laboratório Associado de Sensores e Materiais, Instituto Nacional de Pesquisas Espaciais, CP 515, So José dos CamposSP, CEP 12.245970, Brazil. anderson@las.inpe.br
Antunes
Erica F
EF
Palma
Mariana Bs
MB
Pacheco-Soares
Cristina
C
Trava-Airoldi
Vladimir J
VJ
Corat
Evaldo J
EJ
D002460:Cell Line; D049109:Cell Proliferation; D006801:Humans; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon; D010006:Osteoblasts / Q000166:cytology*
D037742:Nanotubes, Carbon