Hyperlipidemia in older adults.
Older adults carry the highest risk for coronary artery disease and the highest burden of atherosclerosis. Although most clinical trials of cholesterol-lowering therapy have not specifically targeted older persons, growing evidence supports treatment of elevated low-density lipoprotein cholesterol levels in older patients, especially those at high risk for coronary events. The decision to treat a high or high-normal cholesterol level in an elderly individual must be individualized based on chronologic and physiologic age. This article summarizes current data on lipid-lowering therapy in older adults and the management of hyperlipidemia in elderly patients.
Aslam
Farhan
F
Department of Cardiology, Harvard Medical School, Brigham and Women's/Faulkner Hospitals, 1153 Centre Street, Boston, MA 02130, USA.
Haque
Attiya
A
Lee
L Veronica
LV
Foody
JoAnne
J
D000368:Aged; D000924:Anticholesteremic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D008078:Cholesterol, LDL / Q000097:blood; D003131:Combined Modality Therapy; D003324:Coronary Artery Disease / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control*; D018752:Diet, Fat-Restricted; D004043:Dietary Fiber / Q000008:administration & dosage; D015444:Exercise; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology; D008019:Life Style; D016032:Randomized Controlled Trials as Topic
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D004043:Dietary Fiber; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors