[Using a new generation of classification system of antineoplastic drugs to guide Chinese medicine research].
A new generation of classification system of antineoplastic drugs was put forward based on comparing the first with the second generation classification system of antineoplastic drugs. Antineoplastic drugs are divided into cytotoxic drug, cells biological behavior regulator, biological response modifier and biochemical modulator. The using of biological response modifier (immune modulator for instance) and biochemical modulator are supplementary methods for Western medicine treatment in tumor, because the cytotoxic effects of Chinese herbs are lower than those of chemotherapeutic drugs. For the new breakthrough of Chinese medicine oncology research, new idea, new technology and new target should be used, the Chinese medicine mechanism should be studied from a new view. Reversing abnormal biological behavior of tumor cells by Chinese medicine could be an important breakthrough of Chinese medicine oncology research.
Wu
Xiong-Zhi
XZ
Department of Integrative Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin. ilwxz@163.com
D000970:Antineoplastic Agents / Q000145:classification* / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008517:Phytotherapy
D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal