Prevalence of antiphospholipid antibodies among women experiencing unexplained infertility and recurrent implantation failure.
The prevalences of antiphospholipid antibodies (APAs) among 1,325 women with a history of unexplained infertility and 676 women experiencing recurrent implantation failure were compared with 789 women experiencing recurrent pregnancy loss and 205 fertile control women. Eight percent and 9% of women with a history of unexplained infertility and recurrent implantation failure had more than one positive APA compared with 1.5% of fertile negative control women and 11% of positive control women experiencing recurrent pregnancy loss.
Sauer
Ruben
R
National Institute of Perinatology, Mexico City, Mexico.
Roussev
Roumen
R
Jeyendran
Rajasingam S
RS
Coulam
Carolyn B
CB
D000026:Abortion, Habitual / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D017152:Antibodies, Antiphospholipid / Q000032:analysis / Q000097:blood*; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D016022:Case-Control Studies; D010064:Embryo Implantation / Q000276:immunology; D004624:Embryo Transfer; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D008297:Male; D011247:Pregnancy; D017697:Premenopause / Q000097:blood / Q000276:immunology; D016036:Seroepidemiologic Studies; D017211:Treatment Failure
D017152:Antibodies, Antiphospholipid