The role of imaging in the surgical treatment of movement disorders.
Functional neurosurgery involves precise surgical targeting of anatomic structures to modulate neurologic function. From its conception, advances in the surgical treatment of movement disorders have been intertwined with developments in medical imaging, culminating in the use of stereotactic magnetic resonance imaging (MRI). Meticulous attention to detail during image acquisition, direct anatomic localization, and planning of the initial surgical trajectory allows the surgeon to reach the desired anatomic and functional target with the initial trajectory in most cases, thus reducing the need for multiple passes through the brain, and the associated risk of hemorrhage and functional deficit. This philosophy is of paramount importance in a procedure that is primarily aimed at improving quality of life. Documentation of electrode contact location by means of stereotactic imaging is essential to audit surgical targeting accuracy and to further the knowledge of structure-to-function relationships within the human brain.
Zrinzo
Ludvic
L
Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK. l.zrinzo@ion.ucl.ac.uk
D000818:Animals; D001921:Brain / Q000473:pathology / Q000601:surgery; D006801:Humans; D009069:Movement Disorders / Q000473:pathology* / Q000601:surgery*; D019635:Neurosurgical Procedures / Q000379:methods*