title: Lack of evidence of myocardial damage in children with Plasmodium falciparum severe and complicated malaria from an endemic area for endomyocardial fibrosis.
abstract: Malaria is among the factors thought to be involved in the pathogenesis of endomyocardial fibrosis (EMF), a restrictive cardiomyopathy of unclear etiology, with no specific therapy, which affects predominantly children and adolescents. In Africa, regions endemic with EMF are also areas with high prevalence of malaria. We studied 47 consecutive children aged 5- to 15-years old and concluded that myocardial damage and dysfunction are rare in severe and complicated Plasmodium falciparum malaria cases in children.
authors: Instituto do Coração, Moçambique. amocumbl@yahoo.com
authors: Ana Olga
authors: AO
authors: Mocumbi
authors: Mário
authors: M
authors: Songane
authors: Cristolde
authors: C
authors: Salomão
authors: Rogelio
authors: R
authors: Ulibarri
authors: Maria Beatriz
authors: MB
authors: Ferreira
authors: Magdi H
authors: MH
authors: Yacoub
mesh_terms: D000293:Adolescent; D000818:Animals; D015415:Biomarkers / Q000097:blood; D009202:Cardiomyopathies / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D004719:Endomyocardial Fibrosis / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007303:Insect Vectors; D016778:Malaria, Falciparum / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D009073:Mozambique / Q000453:epidemiology; D010963:Plasmodium falciparum / Q000302:isolation & purification; D015995:Prevalence; D012189:Retrospective Studies; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D020107:Troponin T