Magnetic resonance imaging appearance of ovarian stromal hyperplasia and ovarian hyperthecosis.
Ovarian stromal hyperplasia and ovarian hyperthecosis are non-neoplastic conditions of the ovary associated with clinical manifestations of hyperandrogenism from ovarian production of male hormones. In this article, we present the first published cases of the magnetic resonance imaging appearance of these conditions, which may mimic that of ovarian neoplasm. In contrast to bilateral ovarian vein sampling, magnetic resonance imaging may provide a noninvasive means of suggesting a diagnosis of ovarian stromal hyperplasia/ovarian hyperthecosis when a hormone-secreting ovarian neoplasm is suspected clinically and thereby may assist in identifying patients who may be effectively treated nonsurgically with gonadotrophin-releasing hormone therapy.
Rosenkrantz
Andrew B
AB
Department of Radiology, NYU Langone Medical Center, New York, NY. NY 10016, USA. rosena23@nyumc.org
Popiolek
Dorota
D
Bennett
Genevieve L
GL
Hecht
Elizabeth M
EM
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D010049:Ovarian Diseases / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology*