title: Electrophysiologic and anatomical relationships studied in primum atrioventricular septal defect.
abstract: Anatomy and pattern of electrical activation predict the function and contraction pattern of the heart. Patients with primum atrioventricular septal defect (primum AVSD) present with abnormality of both anatomical arrangements and electric activation and serve therefore as an interesting population for studying electro-anatomic relationships in the heart. Understanding the relationships between anatomic and electrophysiologic abnormality is appropriate not only for diagnosis, therapy, and prognosis in patients with primum AVSD but also for understanding the developmental relationship between the conduction system and heart structures, in general. This article presents a review of the anatomical and electrophysiologic characteristics of patients with primum AVSD and provides recent knowledge of electroanatomical relationships of the heart.
authors: Children's Heart Centrum, Lund University Hospital, Lund, Sweden. nina.hakacova@skane.se
authors: Nina
authors: N
authors: Hakacova
mesh_terms: D004562:Electrocardiography / Q000379:methods*; D006325:Heart Atria / Q000002:abnormalities* / Q000473:pathology*; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans