title: Cogan's syndrome with left main coronary artery occlusion.
abstract: Cogan's syndrome is a rare idiopathic chronic inflammatory disease of the eye and the inner ear in young adults. Cogan's syndrome can be associated with large vessel vasculitis. We report a young female, with a history of interstitial keratitis and audiovestibular disease, who presents with large vessel vasculitis with left main coronary artery occlusion and develops heart failure. Cogan's syndrome was diagnosed on the basis of the presence of large vessel vasculitis with the typical inner ear and ocular involvement.
authors: Department of Cardiology, ZNA Hospital Middelheim Antwerp, Belgium. tim_weyn@hotmail.com
authors: Tim
authors: T
authors: Weyn
authors: Steven
authors: S
authors: Haine
authors: Viviane
authors: V
authors: Conraads
mesh_terms: D000328:Adult; D019917:Blood Vessel Prosthesis Implantation; D002317:Cardiovascular Agents / Q000627:therapeutic use; D055952:Cogan Syndrome / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D003131:Combined Modality Therapy; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D054059:Coronary Occlusion / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004562:Electrocardiography; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006333:Heart Failure / Q000209:etiology / Q000628:therapy; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000628:therapy; D020551:Pulse Therapy, Drug; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide