title: Within-household sharing of a fluoroquinolone-resistant Escherichia coli sequence type ST131 strain causing pediatric osteoarticular infection.
abstract: A fluoroquinolone-resistant Escherichia coli strain of sequence type ST131 caused severe septic arthritis and contiguous osteomyelitis in an 8-month-old girl, and colonized the girl's healthy mother, who shared a different fecal E. coli strain with the father. Within-household transmission can contribute to the dissemination of the emerging, multidrug-resistant ST131 clonal group, which has evident invasive potential for otherwise-healthy children.
authors: Infectious Diseases Section, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA. johns007@umn.edu
authors: James R
authors: JR
authors: Johnson
authors: John T
authors: JT
authors: Anderson
authors: Connie
authors: C
authors: Clabots
authors: Brian
authors: B
authors: Johnston
authors: Michael
authors: M
authors: Cooperstock
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D002353:Carrier State / Q000382:microbiology; D016000:Cluster Analysis; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology / Q000635:transmission*; D005191:Family Characteristics; D005192:Family Health; D005260:Female; D024841:Fluoroquinolones / Q000494:pharmacology*; D041981:Gastrointestinal Tract / Q000382:microbiology; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D010003:Osteoarthritis / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D024841:Fluoroquinolones