title: Mitosis: too much of a good thing (can be bad).
abstract: Recent studies reveal that the precise regulation of microtubule dynamics is essential for an error-free mitosis. Kinetochore microtubule attachments that are too stable increase the rate of chromosome mis-segregation, a leading cause of chromosomal instability in tumors.
authors: Wadsworth Center, Albany, NY 12201-0509, USA. khodj@wadsworth.org
authors: Alexey
authors: A
authors: Khodjakov
authors: Conly L
authors: CL
authors: Rieder
mesh_terms: D043171:Chromosomal Instability; D006801:Humans; D018386:Kinetochores; D008870:Microtubules; D008938:Mitosis