Intracranial hemangiomas in a patient with POEMS syndrome.
POEMS syndrome is a rare multi-system disease with typical features of polyneuropathy, organomegaly, endocrinopathy, monoclonal plasmaproliferative disorder and skin changes. We describe a 44-year-old woman with polyneuropathy, hepatomegaly, IgA lambda-plasmacytoma, thrombocytosis, papilledema with elevated protein levels in cerebrospinal fluid and multiple cutaneous hemangiomas who was diagnosed with three intracranial lesions. Histology revealed capillary hemangiomas, one of them displaying partially glomeruloid features.
Maurer
G D
GD
Schittenhelm
J
J
Ernemann
U
U
Kempf
V A J
VA
Ritz
R
R
Weller
M
M
Schmidt
F
F
D015415:Biomarkers / Q000097:blood; D001921:Brain / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D004172:Diplopia / Q000276:immunology / Q000503:physiopathology; D005260:Female; D020786:Hemangioma, Cavernous, Central Nervous System / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D019635:Neurosurgical Procedures; D016878:POEMS Syndrome / Q000150:complications*; D010523:Peripheral Nervous System Diseases / Q000276:immunology / Q000503:physiopathology; D010954:Plasmacytoma / Q000150:complications / Q000276:immunology; D011859:Radiography; D016896:Treatment Outcome; D015854:Up-Regulation / Q000502:physiology; D042461:Vascular Endothelial Growth Factor A / Q000097:blood; D015354:Vision, Low / Q000276:immunology / Q000503:physiopathology
D015415:Biomarkers; D007070:Immunoglobulin A; D042461:Vascular Endothelial Growth Factor A