Intestinal volvulus with coagulative hepatic necrosis in a chicken.
A 7-week-old SPF chicken inoculated at 4 weeks of age with chicken anemia virus was puffed up depressed and had ruffled feathers and a good body condition. Intestinal volvulus involving the jejunum and part of the duodenum forming two loops with one knob was observed. Microscopically, venous infarction of the obstructed loops, periportal and sublobular multifocal coagulative hepatic necrosis and granulomatous inflammation of the cecal tonsils were observed. Gram staining revealed no bacteria in hepatic tissue; however, gram-positive bacilli were detected in the necrotic debris in the intestinal lumen. Immunosuppression might have predisposed the chicken to intestinal and cecal tonsil infection that then progressed to volvulus. Loss of the mucosal barrier in infarction might allow bacterial toxins and vasoactive factors to escape into the systemic circulation (toxemia) and be responsible for the hepatic necrosis.
Haridy
Mohie
M
Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Science, Gifu University.
Goryo
Masanobu
M
Sasaki
Jun
J
Okada
Kosuke
K
D000818:Animals; D017727:Chicken anemia virus / Q000302:isolation & purification*; D002645:Chickens; D018173:Circoviridae Infections / Q000175:diagnosis / Q000662:veterinary*; D018450:Disease Progression; D004386:Duodenum / Q000473:pathology / Q000821:virology; D007413:Intestinal Mucosa / Q000473:pathology / Q000821:virology; D045822:Intestinal Volvulus / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D007583:Jejunum / Q000473:pathology / Q000821:virology; D008297:Male; D047508:Massive Hepatic Necrosis / Q000473:pathology / Q000662:veterinary*