title: Surgical treatment of primary intracranial myxoma in a child following radiotherapy: case report and review of the literature.
abstract: BACKGROUND
  Myxomas are benign tumors of the mesenchymal origin and account for about half of the benign cardiac tumors. Occasionally, they occur at other locations, but the intracranial manifestation of a myxoma is exceptionally rare. As a secondary neoplasia following radiotherapy, myxoma has only been reported once in the literature.
  
  
  METHODS
  A 12-year-old girl, who was previously treated for a medulloblastoma, was diagnosed with a new lesion at the left transverse sinus in the follow-up magnetic resonance imaging (MRI). Indication for surgery was made and complete removal could be achieved.
  
  
  CONCLUSIONS
  Histological examination revealed a myxoma. Further staging showed no other manifestation of the myxoma. The close relation to the radiation field of the posterior fossa makes it highly suggestive that the myxoma developed as a secondary neoplasia induced by radiotherapy. Treatment philosophy for this benign tumor entity is a completed resection of the lesion with regular follow-up MRI.
authors: Department of Neurosurgery, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany. Oliver.mueller@uk-essen.de
authors: Oliver M
authors: OM
authors: Mueller
authors: Johannes A P
authors: JA
authors: van de Nes
authors: Regina
authors: R
authors: Wieland
authors: Beate
authors: B
authors: Schoch
authors: Ulrich
authors: U
authors: Sure
mesh_terms: D001921:Brain / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000473:pathology / Q000532:radiotherapy*; D009232:Myxoma / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D011859:Radiography; D013997:Time Factors