Femur metastasis in carcinoma of the uterine cervix: a rare entity.
OBJECTIVE
We report the first case of isolated femur metastasis in a locally advanced cervical cancer (LACC) patients.


METHODS
A 40-year-old woman presenting with carcinoma of the uterine cervix, FIGO stage IIb was administered concomitant chemo-radiation and achieved clinical partial response. Before the planned surgery, she developed an isolated metastatic lytic lesion of the left femur. After surgical excision of metastasis, she refused palliative chemotherapy, and radiotherapy, and died 3 months later because of progression of the disease.


CONCLUSIONS
Bone metastasis is not so infrequent in patients with LACC. Because the prognosis of these patients is poor and most of them die within 1 year after the diagnosis of metastatic disease, the policy of treatment should be directed to maintain their quality of life.
Corrado
Giacomo
G
Gynecologic Oncology Unit, Department of Oncology, Catholic University of the Sacred Heart, L.go A. Gemelli, 1, 86100, Campobasso, Italy. giacomo.corrado@alice.it
Santaguida
Salvatore
S
Zannoni
Gianfranco
G
Scambia
Giovanni
G
Ferrandina
Gabriella
G
D000328:Adult; D002277:Carcinoma / Q000556:secondary*; D005260:Female; D005266:Femoral Neoplasms / Q000556:secondary*; D005269:Femur / Q000473:pathology*; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000473:pathology*