The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix.
In this paper, we present the results of a study on the membrane-active properties of gossypol, its derivatives and their polyvinylpyrrolidone complexes as assessed by differential scanning calorimetry and by the fluorescent probe method. The latter revealed the change in polarization of the incident radiation caused by the action of the polyphenol on the artificial membrane lipid matrix.
Ionov
Maksim
M
A.S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of Uzbekistan, 83, st, Kh. Abdullaev, Tashkent, 100125, Uzbekistan. maksion@biol.uni.lodz.pl
Tukfatullina
Ilnora
I
Salakhutdinov
Bakhtiyar
B
Baram
Nina
N
Bryszewska
Maria
M
Aripov
Takhir
T
D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006072:Gossypol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry* / Q000378:metabolism; D011205:Povidone / Q000737:chemistry* / Q000378:metabolism; D013816:Thermodynamics
D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D008081:Liposomes; D015060:1,2-Dipalmitoylphosphatidylcholine; D011205:Povidone; D006072:Gossypol; D004134:Dimyristoylphosphatidylcholine