Hereditary osteodystrophy with multiple hormone resistance--a case report.
Hereditary Osteodystrophy, also called pseudohypoparathyroidism, Type 1A (PHP), is a very rare condition composed of a heterogeneous group of autosomal dominant disorders with the common feature of organ resistance to multiple hormones. These patients produce the right amount of hormones but there is resistance to its effect. PHP is difficult to diagnose and the lack of diagnosis may have serious implications for the patient. We report a case of PHP, diagnosed by the dentist, due to the dental and jaw manifestations.
Velez
Ines
I
Oral and Maxillofacial Pathology, Nova Southeastern University, College of Dental Medicine, USA. ivelez@nova.edu
Bond
Melanie
M
Ellen
Steven
S
Ede-Nichols
Diane
D
Larumbe
Jose
J
Oramas
Victor
V
Arnold
Daniel
D
D000293:Adolescent; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging / Q000209:etiology*; D003744:Dental Enamel Hypoplasia / Q000000981:diagnostic imaging / Q000209:etiology*; D003803:Dentigerous Cyst / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D010281:Parathyroid Hormone / Q000378:metabolism; D011547:Pseudohypoparathyroidism / Q000150:complications* / Q000378:metabolism; D011859:Radiography; D014095:Tooth, Impacted / Q000000981:diagnostic imaging / Q000209:etiology; D014807:Vitamin D / Q000378:metabolism
D010281:Parathyroid Hormone; D014807:Vitamin D