title: Primary malignant non-Hodgkin's lymphomas of salivary glands.
abstract: We evaluated the medical record of patients with salivary gland neoplasms diagnosed at Timisoara City Hospital from 2002 to 2009. A study has been carried out for seven years on 204 cases of salivary gland tumors and only two cases of salivary gland lymphomas were diagnosed. The two cases were females of 71- and 49-year-old, respectively. The formalin-fixed paraffin-embedded tissue samples were cut in 4 mum thick sections and stained with Hematoxylin and Eosin. The primary monoclonal antibodies for the immunohistochemical analysis were the followings: LCA (2B11, Dako), CD20 (L26, Dako), cytokeratin (MNF116, Dako), p53 (DQ-7, Dako), and PCNA (PC-10, Dako). The histopathology and immunohistochemistry suggested in the first case a low-grade diffuse large B-cell mucosa associated lymphoid tissue lymphoma and in the second case a high-grade extranodal marginal zone B-cell lymphoma.
authors: Department of Pathology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania. alexandra_pantu@yahoo.co
authors: Alexandra
authors: A
authors: Faur
authors: Elena
authors: E
authors: Lazăr
authors: Mărioara
authors: M
authors: Cornianu
authors: Alis
authors: A
authors: Dema
authors: Codruţa
authors: C
authors: Lăzureanu
authors: Anca
authors: A
authors: Mureşan
authors: Sorina
authors: S
authors: Tăban
mesh_terms: D000368:Aged; D018951:Antigens, CD20 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology*; D008875:Middle Aged; D011379:Prognosis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012383:Romania; D012468:Salivary Gland Neoplasms / Q000401:mortality / Q000473:pathology*; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
chemical_list: D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D018809:Proliferating Cell Nuclear Antigen; D016159:Tumor Suppressor Protein p53; D007633:Keratins