Six-channel neural signal regeneration integrated circuit.
A six-channel neural signal regeneration integrated circuit (IC) was designed and fabricated in CSMC's 0.5-microm CMOS technology. The circuit consists of a low-noise and high common mode rejection ratio (CMRR) instrument amplifier, an inverted operational amplifier (OPA) and a buffer. The six-channel IC occupies a die area of 1.9mmx1.6mm. The testing result shows that the consumption of a single channel is less than 5 mW, and the output voltage swing reaches 5 V under +/-2.5V power supply, the gain can be adjusted from 60dB to 110dB. The circuit has been used for in-vivo experiments on toad's nerve with electrodes to regenerate neural signals. Different neural signals have been successfully regenerated on toad's nerve and corresponding actions have been observed.
Li
Wenyuan
W
Institute of RF- & OE-ICs, Southeast University, 210096 Nanjing, China. lwy555@seu.edu.cn
Wang
Fei
F
Wang
Zhigong
Z
Lu
Xiaoying
X
Shen
Xiaoyan
X
D000818:Animals; D002025:Bufonidae; D004566:Electrodes; D016571:Neural Networks, Computer; D018511:Systems Integration