title: [Relationship between quality of life and BODE index of stable ex-smokers with chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  This study was carried out to assess relationship between quality of life (QoL) and disease severity expressed by multifactorial prognostic index (BODE) in ex-smokers suffering from chronic obstructive pulmonary disease (COPD), minimally 8 weeks free of exacerbation.
  
  
  METHODS
  The evaluation was performed in 98 randomly recruited COPD patients enrolled into a cross-sectional, observational CILIARY study at the Department of Pneumology, Charles University, Faculty of Medicine in Hradec Králové. In them, quality of life evaluation using the SGRQ questionnaire and the BODE index calculation was performed. We statistically compared interrelationship between BODE and COPD stages, SGRQ and COPD stages and interrelation of BODE and SGRQ.
  
  
  RESULTS
  We found significant differences in QoL of COPD patients and QoL in group of healthy volunteers (p <0.001). Lower QoL and higher BODE score were associated with a higher stages of COPD (p < 0.001), with the exception non-significant difference in QoL (SGRQ score) and BODE index between stages I and II. Our study found positive correlation between the all SGRQ scores and multidimensional prognostic BODE index (r = 0.431-0.704). The strongest correlation (r = 0.704) was evident in activity domain of SGRQ.
  
  
  CONCLUSIONS
  Our results proved close correlation ofquality of life (SGRQ) and multidimensional prognostic score (BODE) in stable COPD exsmokers' population. Both these scoring systems are useful tools for the assessment of clinical course and stratification of severity of COPD. However at present both scales are minimally used in the Czech Republic.
authors: Plicní klinika Lékarské fakulty UK a FN Hradec Králové. koblizek@fnhk.cz
authors: V
authors: V
authors: Koblízek
authors: F
authors: F
authors: Salajka
authors: E
authors: E
authors: Cermáková
authors: M
authors: M
authors: Tomsová
authors: D
authors: D
authors: Pohnetalová
authors: P
authors: P
authors: Papousek
authors: V
authors: V
authors: Bartos
authors: T
authors: T
authors: Dobesová
authors: Z
authors: Z
authors: Paráková
authors: J
authors: J
authors: Ruta
authors: V
authors: V
authors: Sedlák
mesh_terms: D000368:Aged; D004417:Dyspnea; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011788:Quality of Life; D016540:Smoking Cessation; D011795:Surveys and Questionnaires