title: Giant retroperitoneal liposarcoma with mixed histological pattern: a rare presentation and literature review.
abstract: BACKGROUND
  Retroperitoneal liposarcoma is a rare tumor that may grow to a considerable size before causing clinical symptoms. Mixed-type retroperitoneal liposarcoma is a very rare clinical entity.
  
  
  METHODS
  We herein describe a rare case of a 54-year-old female who was diagnosed with a giant retroperitoneal liposarcoma arising from the right perinephric space.
  
  
  RESULTS
  Radical nephrectomy and right salpingo-oophorectomy were necessary to achieve complete tumor excision. Histological examination revealed a mixed-type liposarcoma consisting of well-differentiated and pleomorphic elements and deep invasion into the renal parenchyma, which is quite infrequent. The patient was well and disease-free 12 months after surgery.
  
  
  CONCLUSIONS
  Mixed-type retroperitoneal liposarcoma is a rare tumor. Aggressive surgical resection of the tumor together with adjacent structures, if necessary, is the mainstay of treatment.
authors: 2nd Department of Surgery, Army Veterans General Hospital, 10-12 Monis Petraki Str, 15121 Athens, Greece. nikos_salemis@hotmail.com
authors: Nikolaos S
authors: NS
authors: Salemis
authors: Evangelos
authors: E
authors: Tsiambas
authors: Andreas
authors: A
authors: Karameris
authors: Efstathios
authors: E
authors: Tsohataridis
mesh_terms: D005260:Female; D006801:Humans; D008080:Liposarcoma / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000473:pathology* / Q000601:surgery