[Effect of Yupingfeng on the level of salivary epidermal growth factor in oral lichen planus].
OBJECTIVE
To examine the effect of mouthwash Yupingfeng on the level of salivary epidermal growth factor (sEGF) in oral lichen planus (OLP).


METHODS
The level of sEGF was measured by radioimmunoassay with ligand 125I-EGF. The saliva samples were taken from the normal control group and the OLP patients before and after treatment with Yupingfeng.


RESULTS
The levels of sEGF in OLP patients before treatment with Yupingfeng were (4.09 +/- 3.64) microg/L, which was significantly higher than that in normal control [(2.15 +/- 1.62) microg/L, P = 0.013], and (2.57 +/- 1.19) microg/L after treatment,which was significantly lower than before treatment (P = 0.05).


CONCLUSIONS
Yupingfeng can modulate the level of sEGF in OLP patients.
Fan
Yuan
Y
Institute of Stomatology, Nanjing Medical University & Department of Oral Medicine, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China. fanyuan65@hotmail.com
Xu
Juan-Yong
JY
Liu
Qing-Lan
QL
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004815:Epidermal Growth Factor / Q000378:metabolism*; D005260:Female; D006801:Humans; D017676:Lichen Planus, Oral / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism
D004365:Drugs, Chinese Herbal; C532967:yupingfeng; D004815:Epidermal Growth Factor