title: Seroprevalence and genetic characteristics of five subtypes of influenza A viruses in the Chinese pig population: a pooled data analysis.
abstract: A literature review and pooled data analysis were carried out to examine the prevalence of antibodies against five influenza virus subtypes in pigs in China over a 10-year period (1999-2009). The average seropositive frequencies of subtypes H1, H3, H5, H7 and H9 were 3478/11,168 (31.1%), 2900/10,139 (28.6%), 77/5945 (1.3%), 0/1440 (0%) and 86/3619 (2.4%), respectively. There was a geographical variation in the seroprevalence of subtype H1, with the highest seroprevalence in pigs in South and East China. BLAST analysis of genetic sequences revealed that genome segments with moderate homology to the 2009 pandemic influenza A (H1N1) virus were present among swine influenza viruses isolated in China, especially in South and East China. It was concluded from both serological and genetic studies that subtypes H1, H3, H5 and H9 are currently co-circulating in pigs in China, with the H1 subtype most commonly detected, followed by H3.
authors: Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 100071 Beijing, PR China.
authors: Wei
authors: W
authors: Liu
authors: Mao-Ti
authors: MT
authors: Wei
authors: Yigang
authors: Y
authors: Tong
authors: Fang
authors: F
authors: Tang
authors: Lei
authors: L
authors: Zhang
authors: Liqun
authors: L
authors: Fang
authors: Hong
authors: H
authors: Yang
authors: Wu-Chun
authors: WC
authors: Cao
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002681:China / Q000453:epidemiology; D016679:Genome, Viral; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification; D009980:Influenza A virus / Q000235:genetics* / Q000276:immunology*; D009976:Orthomyxoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D016036:Seroepidemiologic Studies; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000276:immunology / Q000821:virology*
chemical_list: D000914:Antibodies, Viral