title: Documentation of congenital hypertrophy of the retinal pigment epithelium with wide-field funduscopy.
abstract: BACKGROUND
  Congenital hypertrophy of the retinal pigment epithelium (CHRPE) are rare hyperpigmented fundus lesions of the peripheral retina.
  
  
  METHODS
  We evaluated CHRPE with the Optomap wide-field fundus camera.
  
  
  RESULTS
  The pattern, location, and extension of the pigmented lesion were compared between the wide-field and composed digital fundus camera. The wide-field image had the same angle of the fundus image, magnification as well homogenious illumination of the entire fundus. Superimposed pattern of the lesions extended from the margin of the optic disk and radiated in sectors to the fundus periphery. Smaller lesion clusters were mainly located near the optic disk, whereas larger lesions were found in the periphery.
  
  
  CONCLUSIONS
  The sectorial pigmentations on the ocular fundus may reflect the stream, outgrowth and migration of RPE-cells during embryogenesis.
authors: Department of Ophthalmology, University of Bonn, Germany.
authors: Carsten H
authors: CH
authors: Meyer
authors: Frank G
authors: FG
authors: Holz
mesh_terms: D000328:Adult; D002465:Cell Movement; D005260:Female; D006801:Humans; D006984:Hypertrophy; D019721:Ophthalmoscopes; D009887:Ophthalmoscopy / Q000379:methods*; D012164:Retinal Diseases / Q000151:congenital* / Q000473:pathology*; D055213:Retinal Pigment Epithelium / Q000002:abnormalities* / Q000473:pathology*