Therapeutic advances in malignant glioma: current status and future prospects.
This article reviews the current status and trends in the treatment of primary gliomas, focusing predominantly on glioblastoma. It also discusses the current standard of care and new targeted agents currently under investigation. Furthermore, the concepts of pseudoprogression and pseudoresponse are introduced, which are new imaging correlates that have significant impact on understanding of the disease.
Robins
H Ian
HI
Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.
Lassman
Andrew B
AB
Khuntia
Deepak
D
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000628:therapy*; D004358:Drug Therapy / Q000639:trends*; D005910:Glioma / Q000628:therapy*; D006801:Humans; D019635:Neurosurgical Procedures / Q000639:trends*; D011878:Radiotherapy / Q000639:trends*
D000970:Antineoplastic Agents