title: Bilateral angiosarcoma of the breast detected by magnetic resonance imaging during pregnancy.
abstract: Angiosarcoma of the breast is an aggressive malignancy of endothelial origin with a tendency for local regional recurrence. The involvement of angiosarcomas in the bilateral breasts has rarely been documented. Of note, due to its rarity and typically unclear clinical findings upon examination, the diagnosis of a contralateral lesion can be difficult, particularly in women during pregnancy. Here we present a rare case of bilateral angiosarcoma of the breast during pregnancy. A 32-year-old woman was referred to our unit with complaints of progressive swelling of the left breast, with tenderness. Magnetic resonance imaging showed a small, circumscribed high-intensity area in the contralateral breast, with pattern similar to that of the lesion found in the left breast. The contralateral lesion revealed only equivocal findings with the other diagnostic modalities. Diagnosed as angiosarcoma preoperatively, excision of the bilateral tumors was performed. Histological findings of the removed bilateral tumors were compatible with high-grade angiosarcoma of the breast.
authors.affiliation: Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2-5-1 Shikata, Okayama 700-8558, Japan. cqs03255@nifty.com
authors.forename: Takeo
authors.initials: T
authors.lastname: Fujita
authors.forename: Naruto
authors.initials: N
authors.lastname: Taira
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ogasawara
authors.forename: Masako
authors.initials: M
authors.lastname: Omori
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Doihara
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D042361:Mammary Glands, Human / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000473:pathology