Effective components of TORDIA cognitive-behavioral therapy for adolescent depression: preliminary findings.
In this report, we conducted a secondary analysis of the Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study to explore the impact of specific cognitive-behavioral therapy (CBT) treatment components on outcome. In TORDIA, 334 youths (ages 12 to 18 years) with major depressive disorder who had failed to respond to an adequate course of selective serotonin reuptake inhibitor (SSRI) medication were randomized to a medication switch (either to an alternative SSRI or venlafaxine) with or without 12 weeks of adjunctive CBT. Participants who had more than 9 CBT sessions were 2.5 times more likely to have adequate treatment response than those who had 9 or fewer sessions. CBT participants who received problem-solving and social skills treatment components, controlling for number of sessions and other confounding variables, were 2.3 and 2.6 times, respectively, more likely to have a positive response. These preliminary findings underscore the importance of receiving an adequate number of sessions to attain an adequate clinical response. Finally, social skills and problem solving may be active elements in CBT for adolescent depression and should be considered in treatment by those working with seriously depressed youths.
Kennard
Betsy D
BD
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390-8589, USA. Beth.Kennard@UTSouthwestern.edu
Clarke
Greg N
GN
Weersing
V Robin
VR
Asarnow
Joan Rosenbaum
JR
Shamseddeen
Wael
W
Porta
Giovanna
G
Berk
Michele
M
Hughes
Jennifer L
JL
Spirito
Anthony
A
Emslie
Graham J
GJ
Keller
Martin B
MB
Wagner
Karen D
KD
Brent
David A
DA
D000293:Adolescent; D000339:Affect; D016009:Chi-Square Distribution; D002648:Child; D015928:Cognitive Behavioral Therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000628:therapy*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004644:Emotions; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D016017:Odds Ratio; D011340:Problem Solving; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012919:Social Behavior; D016896:Treatment Outcome
D017367:Selective Serotonin Reuptake Inhibitors