title: Phenacetin isolated from Bursera grandifolia, a herbal remedy with antipyretic properties.
abstract: Bursera grandifolia and other related species have been used in traditional herbal medicine in Mexico and other Latin American countries for their analgesic, antipyretic and anti-inflammatory properties. From the chloroform extract of leaves of B. grandifolia, a substance was isolated and identified as phenacetin, a well known compound with widely tested analgesic and antipyretic properties. The structural identity of the compound was elucidated on the basis of chemical and spectroscopic evidence and by comparison with an authentic sample.
authors.affiliation: Departamento de Madera, Celulosa y Papel, CUCEI, Universidad de Guadalajara, Km 15.5, Carretera Guadalajara-Nogales, Guadalajara, Jalisco, Mexico 45020.
authors.forename: Francisco
authors.initials: F
authors.lastname: Velázquez
authors.forename: Ricardo
authors.initials: R
authors.lastname: Manríquez
authors.forename: Leticia
authors.initials: L
authors.lastname: Maya
authors.forename: Lucia
authors.initials: L
authors.lastname: Barrientos
authors.forename: Fernando
authors.initials: F
authors.lastname: López-Dellamary
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000737:chemistry* / Q000302:isolation & purification; D031233:Bursera / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D008800:Mexico; D010615:Phenacetin / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D028321:Plant Preparations / Q000032:analysis
chemical_list: D018712:Analgesics, Non-Narcotic; D028321:Plant Preparations; D010615:Phenacetin