[Development of tumor treatment-related premature ovarian failure and ovarian function reconstruction].
OBJECTIVE
To analyze the reason of tumor treatment-related premature ovarian failure, and to review the progress of ovarian functional reconstruction.


METHODS
The literature about the effects of radiotherapy and chemotherapy on ovarian function and reconstruct ovarian function was reviewed, analysed and summarized.


RESULTS
Radiotherapy and chemotherapy can both affect ovarian function. The ovarian function reconstruction included fresh ovarian transplantation and ovarian cryopreservation and transplantation. Frequent ovarian cryopreservation was procedure slow-freezing protocols and vitrification protocols. Some laboratory and animal models of ovarian function reconstruction have come to gratifying results.


CONCLUSIONS
Ovarian function reconstruction has a potential clinical value and provides a promising future.
Chen
Ping
P
Department of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.
Zhu
Jiang
J
Hou
Mei
M
Xu
Nie
N
D000818:Animals; D005260:Female; D006801:Humans; D016649:Primary Ovarian Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D020127:Recovery of Function