title: Chemical composition and antibacterial activity of the essential oil of Monticalia andicola (Asteraceae) collected in Venezuela.
abstract: The essential oil from the leaves of Monticalia andicola Turcz., collected in November 2008, was analyzed by GC/MS. A yield of 0.15% oil was obtained by hydrodistillation. Thirty-six components were identified by comparison of their mass spectra with those in the Wiley GC-MS Library data base. The major components were alpha-pinene (19.6%), beta-pinene (10.5%), alpha-longipinene (6.5%), delta-3-carene (6.2%), cyperene (5.4%) and beta-phellandrene (5.2%). The antibacterial activity of the essential oil was evaluated against Gram- positive (Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212) and Gram-negative (Escherichia coli ATCC 25992, Klebsiella pneumoniae ATCC 23357, Pseudomonas aeruginosa ATCC 27853) bacteria, using the disc diffusion agar method. The results showed a broad spectrum of activity with minimal inhibitory concentration (MIC) values ranging from 10 to 150 microg/mL.
authors.affiliation: Organic Biomolecular Research Group, Research Institute, Faculty of Pharmacy and Biomedical Sciences, University of Los Andes, Mérida, Venezuela.
authors.forename: Shirley
authors.initials: S
authors.lastname: Baldovino
authors.forename: Janne
authors.initials: J
authors.lastname: Rojas
authors.forename: Luis B
authors.initials: LB
authors.lastname: Rojas
authors.forename: María
authors.initials: M
authors.lastname: Lucena
authors.forename: Alexis
authors.initials: A
authors.lastname: Buitrago
authors.forename: Antonio
authors.initials: A
authors.lastname: Morales
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D014687:Venezuela
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile