Postischemic administration of HLDF-6 peptide ameliorates cognitive dysfunction and brain damage induced by chronic cerebral ischemia in rats.
Kostanyan
I A
IA
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997 Russia.
Storozheva
Z I
ZI
Semenova
N A
NA
Lipkin
V M
VM
D000818:Animals; D021461:Animals, Outbred Strains; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D002545:Brain Ischemia / Q000150:complications* / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D003401:Creatine / Q000378:metabolism; D002534:Hypoxia, Brain / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018782:Maze Learning / Q000187:drug effects; D008568:Memory / Q000187:drug effects; D018696:Neuroprotective Agents / Q000494:pharmacology / Q000627:therapeutic use; D009842:Oligopeptides / Q000494:pharmacology / Q000627:therapeutic use*; D010725:Phosphocreatine / Q000378:metabolism; D010847:Picolines / Q000494:pharmacology / Q000627:therapeutic use; D011619:Psychotropic Drugs / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats
D018696:Neuroprotective Agents; D009842:Oligopeptides; D010847:Picolines; D011619:Psychotropic Drugs; C513648:threonyl-glycyl-glutamyl-asparaginyl-histidylarginine; D010725:Phosphocreatine; C070020:emoxypine succinate; D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine