title: Neuroimaging findings and brain-behavioral correlates in a former boxer with chronic traumatic brain injury.
abstract: Chronic traumatic brain injury (CTBI) is associated with contact sports such as boxing. CTBI results from repetitive blows to the head rather than from a single impact. CTBI individuals present with motor symptoms (incoordination, spasticity, parkinsonism), cognitive impairment (executive dysfunction, memory deficits) and neuropsychiatric symptoms (irritability, affective disturbances). The structural and functional neuroimaging findings and clinical presentation of a CTBI case are described. We propose hypotheses about the pathophysiology of the observed neuroimaging findings and their relationship to the neuropsychiatric symptoms of the patients.
authors.affiliation: University of Connecticut Health Center, Farmington, CT, USA.
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Handratta
authors.forename: Ellen
authors.initials: E
authors.lastname: Hsu
authors.forename: John
authors.initials: J
authors.lastname: Vento
authors.forename: Clifford
authors.initials: C
authors.lastname: Yang
authors.forename: Kaloyan
authors.initials: K
authors.lastname: Tanev
mesh_terms: D001265:Athletic Injuries / Q000473:pathology*; D001284:Atrophy / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D001914:Boxing / Q000293:injuries*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D001930:Brain Injuries / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D001931:Brain Mapping; D002908:Chronic Disease; D003704:Dementia / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D004185:Disability Evaluation; D006212:Hallucinations / Q000209:etiology; D006801:Humans; D020547:Lateral Ventricles / Q000473:pathology; D008297:Male; D001523:Mental Disorders / Q000209:etiology / Q000503:physiopathology; D008875:Middle Aged; D012688:Septum Pellucidum / Q000473:pathology; D012720:Severity of Illness Index; D013995:Time; D015899:Tomography, Emission-Computed, Single-Photon