A comparative analysis of completed suicide using high resolution brain SPECT imaging.
The authors compared regional cerebral blood flow in the brains of 12 psychiatric patients who completed the act of suicide with groups of healthy and nonsuicidal depressed subjects using statistical parametric mapping. Results were consistent with prior imaging studies on depression and were indicative of impaired impulse control and limbic dysregulation, including significant perfusion deficits in the medial prefrontal and subgenual areas (Brodmann's areas 11, 25) and ventral tegmentum. These results warrant further research.
Amen
Daniel G
DG
Amen Clinic, Department of Research and Information Systems, 4019 Westerly Pl., Suite 110, Newport Beach, CA 92660, USA. coloneloftruth@gmail.com
Prunella
Jill R
JR
Fallon
James H
JH
Amen
Breanne
B
Hanks
Chris
C
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001931:Brain Mapping; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation / Q000502:physiology; D003866:Depressive Disorder / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D013405:Suicide; D015899:Tomography, Emission-Computed, Single-Photon