Mydriasis associated with local dysfunction of parasympathetic nerves in two dogs.
In clinical practice, photophobia resulting from persistent mydriasis may be associated with dysfunction of ocular parasympathetic nerves or primary iris lesions. We encountered a 5-year-old Miniature Dachshund and a 7-year-old Shih Tzu with mydriasis, abnormal pupillary light reflexes, and photophobia. Except for sustained mydriasis and photophobia, no abnormalities were detected on general physical examination or ocular examination of either dog. We performed pharmacological examinations using 0.1% and 2% pilocarpine to evaluate and diagnose parasympathetic denervation of the affected pupillary sphincter muscles. On the basis of the results, we diagnosed a pupillary abnormality due to parasympathetic dysfunction and not to overt primary iris lesions. The test revealed that neuroanatomic localization of the lesion was postciliary ganglionic in the first dog.
Kanda
Teppei
T
Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, 4-101, Koyama-minami, Tottori 680-8553, Japan.
Tsuji
Kazuhiro
K
Hiyama
Keiko
K
Tsuka
Takeshi
T
Minami
Saburo
S
Hikasa
Yoshiaki
Y
Furukawa
Toshinori
T
Okamoto
Yoshiharu
Y
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D007249:Inflammation / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary; D008297:Male; D008540:Meiosis; D008916:Miotics / Q000627:therapeutic use; D015878:Mydriasis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*; D020795:Photophobia / Q000209:etiology / Q000662:veterinary; D010862:Pilocarpine / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D008916:Miotics; D010862:Pilocarpine; D011239:Prednisolone