title: [Small cell lung cancer complicated by opsoclonus myoclonus syndrome].
abstract: Opsoclonus myoclonus syndrome, one of the paraneoplastic neurological syndromes involving several neurological symptoms that result from "remote effects" of cancer, is a rare disease characterized by opsoclonus, cerebellar ataxia and myoclonus of the trunk and extremities. A 53-year-old man was admitted with dizziness and difficulty walking. Medical examinations led to a diagnosis of opsoclonus myoclonus syndrome. CT scans showed mediastinal and cervical lymphadenopathy, and a diagnosis of small cell lung cancer was made. Steroid therapy and chemotherapy (carboplatin + etoposide) produced significant improvement in the neurological symptoms.
authors.affiliation: Department of Respiratory Medicine, Shakaihoken Kobe Central Hospital.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Iwata
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yokomura
authors.forename: Shuji
authors.initials: S
authors.lastname: Ohsugi
authors.forename: Ayuko
authors.initials: A
authors.lastname: Uesaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Sekiguchi
authors.forename: Akira
authors.initials: A
authors.lastname: Nishio
mesh_terms: D018288:Carcinoma, Small Cell / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D053578:Opsoclonus-Myoclonus Syndrome / Q000209:etiology*