[Nicotine and benz(alpha)piren concentration in saliva of inveterate tobacco-smokers].
The aim of the work is study in saliva the nicotine and benz(alphapiren concentration dynamic in morning without cigarette, after light first cigarette and after one hour after lighting. All biochemical substances is analyzed and identified chromatographically on Bondo-Pac C(18) column (Liquid Chromatography Millipor-Waters, USA). The conducted quantitative and qualitative analyzes show that at all examinations benz(alpha)piren concentration dynamic in saliva is very differently in compare of nicotine concentration dynamic. The content of benz(alpha)piren in saliva at all analyzes transfer very slowly. Our data show that with the increase of the time the concentration of nicotine in saliva in beginning increase, add then diminish. The studies are necessary to be held in different directions. First, the medical consequences of using the tobacco and the ways of their curing should be identified. The second direction should mean elaboration of preventive measures and programs, or measures of intervention.
Zurabashvili
Z A
ZA
Chanturiaia
I L
IL
Kapanadze
L R
LR
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001580:Benzopyrenes / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000032:analysis*; D012463:Saliva / Q000737:chemistry*; D013997:Time Factors; D014029:Tobacco Use Disorder / Q000175:diagnosis* / Q000453:epidemiology
D001580:Benzopyrenes; D009538:Nicotine