title: Anxiety, depression, and quality of life in Parkinson's disease.
abstract: Parkinson's disease has a major impact on quality of life. This cross-sectional study assessed 43 idiopathic Parkinson's disease patients in order to evaluate the impact of Parkinson's disease severity (Hoehn and Yahr scale), anxiety, and depression (Hospital Anxiety and Depression Scale) on quality of life (Short Form-36 Health Survey questionnaire). Hospital Anxiety and Depression Scale and Short Form-36 Health Survey scores were significantly correlated in Hoehn and Yahr stage 2 Parkinson's disease (n=33), and anxiety had a strong correlation with physical score. Multivariate analysis (n=43) revealed that anxiety was the strongest predictor of quality of life. Anxious and depressive symptoms have a different meaning in Parkinson's disease, and both must be routinely assessed in order to optimize quality of life.
authors.affiliation: Psychiatrist, Pedro Hispano General Hospital, Department of Mental Health - Psychiatry Service, Rua Dr. Eduardo Torres, 4454-509 Matosinhos, Portugal. rosaquelhas@gmail.com
authors.forename: Rosa
authors.initials: R
authors.lastname: Quelhas
authors.forename: Manuela
authors.initials: M
authors.lastname: Costa
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D003430:Cross-Sectional Studies; D003863:Depression / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D012044:Regression Analysis; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires