title: Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
authors.affiliation: Institute of Biological Chemistry, CBMB, Taiwan International Graduate Program, Academia Sinica, 128 Section 2, Academia Road, Nankang, Taipei 11529, Taiwan.
authors.forename: Hsing-Ju
authors.initials: HJ
authors.lastname: Wu
authors.forename: Ching-Wen
authors.initials: CW
authors.lastname: Ho
authors.forename: Tzu-Ping
authors.initials: TP
authors.lastname: Ko
authors.forename: Shinde D
authors.initials: SD
authors.lastname: Popat
authors.forename: Chun-Hung
authors.initials: CH
authors.lastname: Lin
authors.forename: Andrew H-J
authors.initials: AH
authors.lastname: Wang
mesh_terms: D017485:1-Deoxynojirimycin; D001419:Bacteria / Q000201:enzymology; D001665:Binding Sites / Q000187:drug effects; D018360:Crystallography, X-Ray; D054812:Cyclitols / Q000138:chemical synthesis* / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D013329:Structure-Activity Relationship; D013816:Thermodynamics; D005644:alpha-L-Fucosidase / Q000037:antagonists & inhibitors* / Q000737:chemistry
chemical_list: D054812:Cyclitols; D004791:Enzyme Inhibitors; D017485:1-Deoxynojirimycin; D005644:alpha-L-Fucosidase