title: Sacroplasty for local or massive localization of multiple myeloma.
abstract: The purpose of this study was to assess the efficacy of cementoplasty in the treatment of sacral multiple myelomas. We retrospectively reviewed the records of eight patients (four women and four men; age range 47-68 years; mean age 57.8) who underwent cementoplasty for painful osteolytic localization of multiple myeloma between April 2007 and May 2009. The patients had difficulty walking because of increasing pain. Six patients had persistent pain despite other cementoplasties for vertebral and femoral localization, whereas two patients referred at the time of diagnosis had only sacral lesions. The clinical indication for treatment was (1) a pain intensity score ≥5 on visual analogue scale (VAS) and (2) pain totally or partially refractory to analgesic treatment in patients with a life expectancy >3 months. Technical planning was based on computed tomography and/or magnetic resonance imaging. Six patients had previously undergone radiotherapy or chemotherapy and were receiving varying doses of analgesics, whereas sacroplasty represented the first treatment for two patients. Five patients had monolateral local involvement, and the other patients had massive involvement of the sacrum; Technical success was achieved in all cases. We had only one small and asymptomatic foraminal leak. All patients experienced improvement in symptoms after the procedure, as demonstrated by improved VAS scores and performance status (PS) and decreased analgesic dose constant during follow-up. In our experience, percutaneous stabilization can be used effectively and safely in patients with focal or extensive involvement of the sacrum by multiple myeloma.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Ospedale Ferrarotto, via Citelli 6, 95124 Catania, Italy. antodoc@yahoo.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Basile
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Tsetis
authors.forename: Maide
authors.initials: M
authors.lastname: Cavalli
authors.forename: Paolo
authors.initials: P
authors.lastname: Fiumara
authors.forename: Francesco
authors.initials: F
authors.lastname: Di Raimondo
authors.forename: Francesco
authors.initials: F
authors.lastname: Coppolino
authors.forename: Carmelo
authors.initials: C
authors.lastname: Coppolino
authors.forename: Elena
authors.initials: E
authors.lastname: Mundo
authors.forename: Carla
authors.initials: C
authors.lastname: Desiderio
authors.forename: Antonio
authors.initials: A
authors.lastname: Granata
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Patti
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology / Q000601:surgery*; D010147:Pain Measurement; D015641:Radiography, Interventional; D012189:Retrospective Studies; D012447:Sacrum / Q000473:pathology / Q000601:surgery*; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods*