title: Magnetoencephalographic characteristics of psychosis in temporal lobe epilepsy.
abstract: To test the hypothesis that some particular magnetoencephalographic findings characterize psychosis manifesting in temporal lobe epilepsy (TLE) patients, the authors performed statistical analyses on the correlation between a history of psychosis and four magnetoencephalographic spike-dipole patterns, namely, left and right inferotemporal-horizontal (IH) and superotemporal-vertical (SV) types. Fifty-seven patients with TLE were studied, 16 of whom had a history of psychosis. Of the four types of spike-dipoles, only left SV type showed a strong correlation with psychosis, suggesting that dysfunction of the left temporal neocortex specifically contributes to the manifestation of psychotic symptoms in TLE patients.
authors.affiliation: Department of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shôgoin-kawahara-chô, Sakyo-ku, Kyoto City 606-8507, Japan. fukao@kuhp.kyoto-u.ac.jp
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Fukao
authors.forename: Yushi
authors.initials: Y
authors.lastname: Inoue
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Yagi
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D009415:Nerve Net / Q000503:physiopathology*; D018579:Patient Selection; D011618:Psychotic Disorders / Q000150:complications / Q000503:physiopathology*; D012720:Severity of Illness Index