title: Time from first intercourse to first sexually transmitted infection diagnosis among adolescent women.
abstract: OBJECTIVE
  To determine the time between first intercourse and first sexually transmitted infection (STI) with Chlamydia trachomatis, Neisseria gonorrhoeae, or Trichomonas vaginalis and time between repeated infections.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Three adolescent medicine clinics.
  
  
  METHODS
  A cohort of 386 urban young women aged 14 to 17 years at enrollment.
  
  
  METHODS
  Age at first intercourse; organism-specific interval between first intercourse and first STI diagnosis; interval between repeated infections; and age at first STI test prior to study participation.
  
  
  RESULTS
  Participants had first intercourse at a young age (first, second, and third quartiles were 13, 14, and 15 years of age, respectively). By age 15 years, 25% of the women acquired their first STI, most often C trachomatis. Median interval between first intercourse and first STI diagnosis was 2 years. Within 1 year of first intercourse, 25% had their first C trachomatis infection. Repeated infections were common; within 3.6, 6, and 4.8 months, 25% of the women with prior C trachomatis, N gonorrhoeae, and T vaginalis infection were reinfected with the respective organisms. Considerable delay in STI testing was found for those who began sex at a younger age. The median interval between first sex and first test were 4.9, 3.5, 2.1, 1.8, and 1.2 years for those who had first sex at ages 10, 11, 12, 13, and 14 years, respectively.
  
  
  CONCLUSIONS
  Timely screening and treatment are important for prevention of STI sequelae. For urban adolescent women, STI screening (especially for C trachomatis) should begin within a year after first intercourse and infected individuals should be retested every 3 to 4 months.
authors.affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, USA. wtu1@iupui.edu
authors.forename: Wanzhu
authors.initials: W
authors.lastname: Tu
authors.forename: Byron E
authors.initials: BE
authors.lastname: Batteiger
authors.forename: Sarah
authors.initials: S
authors.lastname: Wiehe
authors.forename: Susan
authors.initials: S
authors.lastname: Ofner
authors.forename: Barbara
authors.initials: B
authors.lastname: Van Der Pol
authors.forename: Barry P
authors.initials: BP
authors.lastname: Katz
authors.forename: Donald P
authors.initials: DP
authors.lastname: Orr
authors.forename: J Dennis
authors.initials: JD
authors.lastname: Fortenberry
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000367:Age Factors; D003075:Coitus; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D012749:Sexually Transmitted Diseases / Q000175:diagnosis*; D013997:Time Factors; D014505:Urban Population