Domino ring-opening/carboxamidation reactions of N-tosyl aziridines and 2-halophenols/pyridinol: efficient synthesis of 1,4-benzo- and pyrido-oxazepinones.
A domino process is described for the synthesis of 1,4-benzo- and pyrido-oxazepinones by one-pot sequential ring-opening/carboxamidation reactions of various N-tosylaziridines with a range of 2-halophenols/pyridinol under phase-transfer catalysis.
Chouhan
Gagan
G
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada, K1N 6N5.
Alper
Howard
H