title: Relation between central corneal thickness and intraocular pressure in Punjabi population.
abstract: OBJECTIVE
  The motive of this study was to determine the variation of central corneal thickness (CCT) in the Punjabi population and to examine its relationship with intraocular pressure (IOP) using a non-contact tonometer. The study and results emphasize the effects of age, sex and refraction on this relationship, which is important for the diagnosis and prevention of glaucoma in adequate time.
  
  
  METHODS
  The study design was a cross-sectional, population-based survey. The participants were 279 females and 253 males of Punjab Province, India, in the age group of 21-70 years. The CCT was measured using an ultrasonic pachymeter, and the IOP was measured using an air-puff tonometer in all subjects.
  
  
  RESULTS
  The mean values of CCT and IOP were observed to vary imprecisely with age. The measurement of both parameters was also affected by sex and refraction. The linear regression analysis suggests that the mean value of CCT grows progressively with increasing value of mean IOP. A significant positive correlation was identified between CCT and IOP in the age group of 21-70 years. The authors inferred that this correlation value varies prominently with age for both sexes, which needs to be investigated further.
  
  
  CONCLUSIONS
  The authors suggest that CCT is a noteworthy source of variation in IOP measurements for males as well as females belonging to different age groups, when assessing IOP as a risk for glaucoma in the Punjabi population.
authors.affiliation: Department of Physiology, Rajindra Government Medical College and Hospital, Patiala, Punjab, India. drkohli_iitr@yahoo.co.in
authors.forename: Poonam G
authors.initials: PG
authors.lastname: Kohli
authors.forename: B K
authors.initials: BK
authors.lastname: Randhawa
authors.forename: K D
authors.initials: KD
authors.lastname: Singh
authors.forename: G S
authors.initials: GS
authors.lastname: Randhawa
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Kohli
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003315:Cornea / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D003430:Cross-Sectional Studies; D005260:Female; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D007194:India; D007429:Intraocular Pressure / Q000502:physiology*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D014065:Tonometry, Ocular; D014463:Ultrasonography