The inflammatory reaction during chronic venous disease of lower limbs.
Chronic venous disease (CVD) is an insufficiency of distal veins caused by their partial or total obstruction, endothelial distension and functional disorders. Chronic venous disease of lower limbs is common problem and affects millions of people. In this article we suggest that inflammatory process is involved in the structural remodeling in venous valves and in the venous wall, leading to valvular incompetence and the development of varicose veins.
Ojdana
Dominika
D
Department of Microbiological Diagnostics, Medical University of Białystok, Białystok, Poland.
Safiejko
Kamil
K
Lipska
Alina
A
Sacha
Paweł
P
Wieczorek
Piotr
P
Radziwon
Piotr
P
Dadan
Jacek
J
Tryniszewska
Elzbieta
E
D002908:Chronic Disease; D006801:Humans; D007249:Inflammation; D035002:Lower Extremity / Q000098:blood supply* / Q000503:physiopathology; D014648:Varicose Veins / Q000473:pathology / Q000503:physiopathology; D014652:Vascular Diseases / Q000473:pathology* / Q000503:physiopathology; D014689:Venous Insufficiency