title: The inflammatory reaction during chronic venous disease of lower limbs.
abstract: Chronic venous disease (CVD) is an insufficiency of distal veins caused by their partial or total obstruction, endothelial distension and functional disorders. Chronic venous disease of lower limbs is common problem and affects millions of people. In this article we suggest that inflammatory process is involved in the structural remodeling in venous valves and in the venous wall, leading to valvular incompetence and the development of varicose veins.
authors.affiliation: Department of Microbiological Diagnostics, Medical University of Białystok, Białystok, Poland.
authors.forename: Dominika
authors.initials: D
authors.lastname: Ojdana
authors.forename: Kamil
authors.initials: K
authors.lastname: Safiejko
authors.forename: Alina
authors.initials: A
authors.lastname: Lipska
authors.forename: Paweł
authors.initials: P
authors.lastname: Sacha
authors.forename: Piotr
authors.initials: P
authors.lastname: Wieczorek
authors.forename: Piotr
authors.initials: P
authors.lastname: Radziwon
authors.forename: Jacek
authors.initials: J
authors.lastname: Dadan
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Tryniszewska
mesh_terms: D002908:Chronic Disease; D006801:Humans; D007249:Inflammation; D035002:Lower Extremity / Q000098:blood supply* / Q000503:physiopathology; D014648:Varicose Veins / Q000473:pathology / Q000503:physiopathology; D014652:Vascular Diseases / Q000473:pathology* / Q000503:physiopathology; D014689:Venous Insufficiency