title: Tunable antibacterial coatings that support mammalian cell growth.
abstract: Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on amine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.
authors.affiliation: Mawson Institute, University of South Australia, Mawson Lakes, Adelaide, SA 5095, Australia. krasimir.vasilev@unisa.edu.au
authors.forename: Krasimir
authors.initials: K
authors.lastname: Vasilev
authors.forename: Vasu
authors.initials: V
authors.lastname: Sah
authors.forename: Karine
authors.initials: K
authors.lastname: Anselme
authors.forename: Chi
authors.initials: C
authors.lastname: Ndi
authors.forename: Mihaela
authors.initials: M
authors.lastname: Mateescu
authors.forename: Björn
authors.initials: B
authors.lastname: Dollmann
authors.forename: Petr
authors.initials: P
authors.lastname: Martinek
authors.forename: Hardi
authors.initials: H
authors.lastname: Ys
authors.forename: Lydie
authors.initials: L
authors.lastname: Ploux
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Griesser
mesh_terms: D000268:Adhesiveness; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control*; D002448:Cell Adhesion; D018929:Cell Culture Techniques; D006801:Humans; D007477:Ions; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles; D036103:Nanotechnology / Q000379:methods; D010006:Osteoblasts / Q000166:cytology / Q000382:microbiology; D011108:Polymers / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013212:Staphylococcus epidermidis / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D007477:Ions; D011108:Polymers; D012834:Silver