title: Kinetic study of organic acid formations and growth of Anaerobiospirillum succiniciproducens during continuous cultures.
abstract: Succinic acid-producing Anaerobiospirillum succiniciproducens was anaerobically grown in glucose-fed continuous cultures using glucose as a carbon source, and the metabolic flexibility of A. succiniciproducens in response to varying glucose concentrations and dilution rates was examined. Both succinic acid (SA) and acetic acid (AA) formation was growth-associated, and their growth-rate-related coefficients (KSA/X, KAA/X) and nongrowth-rate-related coefficients (K'SA/X, K'AA/X) were slightly influenced by glucose concentrations. A high glucose concentration (38 g/l) and high growth rate (0.63 h-1) did not induce by-product formation.
authors.affiliation: Department of Molecular Science and Technology, Ajou University, Woncheon-dong, Yeongtong-gu, Suwon 443-749, South Korea. pclee@ajou.ac.kr
authors.forename: Pyung Cheon
authors.initials: PC
authors.lastname: Lee
authors.forename: Sang Yup
authors.initials: SY
authors.lastname: Lee
authors.forename: Ho Nam
authors.initials: HN
authors.lastname: Chang
mesh_terms: D019342:Acetic Acid / Q000378:metabolism*; D000693:Anaerobiosis; D044064:Anaerobiospirillum / Q000254:growth & development / Q000378:metabolism; D018533:Biomass; D019149:Bioreactors; D003470:Culture Media; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D007218:Industrial Microbiology / Q000379:methods; D007700:Kinetics; D019802:Succinic Acid / Q000378:metabolism*
chemical_list: D003470:Culture Media; D019802:Succinic Acid; D005947:Glucose; D019342:Acetic Acid