[Successful treatment of surgically induced necrotizing sclerokeratitis (SINS) with systemic immunosuppresive agents and amniotic membrane grafting].
METHODS
We report the case of a 74-year-old female who developed a necrotizing sclerokeratitis affecting her left eye after uncomplicated cataract surgery. She had no previous history of systemic autoimmune disease. Histopathology of the lesion revealed necrotic granulomatosis with an increased number of plasma cells.


CONCLUSIONS
Surgically induced necrotizing sclerokeratitis (SINS) is a serious entity which requires prompt and aggressive therapy to prevent its potential devastating ocular consequences. Conjunctival resection and amniotic membrane grafting may be necessary to temporarily interrupt local immunologic events in severe cases. However, associated systemic immunomodulatory therapy seems to be mandatory (Arch Soc Esp Oftalmol 2009; 84: 577-580).
Cordero-Coma
M
M
Hospital de León C/. Altos de Nava, s/n 24080 León, España. miguelcorderocoma@gmail.com
Franco-Benito
M
M
García-Ruiz-de-Morales
J M
JM
Alonso-Orcajo
N
N
Del Barrio-Manso
I
I
D000368:Aged; D000650:Amnion / Q000637:transplantation*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007634:Keratitis / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D009336:Necrosis; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D012074:Remission Induction; D015422:Scleral Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy*
D007166:Immunosuppressive Agents