title: [Development of tumor treatment-related premature ovarian failure and ovarian function reconstruction].
abstract: OBJECTIVE
  To analyze the reason of tumor treatment-related premature ovarian failure, and to review the progress of ovarian functional reconstruction.
  
  
  METHODS
  The literature about the effects of radiotherapy and chemotherapy on ovarian function and reconstruct ovarian function was reviewed, analysed and summarized.
  
  
  RESULTS
  Radiotherapy and chemotherapy can both affect ovarian function. The ovarian function reconstruction included fresh ovarian transplantation and ovarian cryopreservation and transplantation. Frequent ovarian cryopreservation was procedure slow-freezing protocols and vitrification protocols. Some laboratory and animal models of ovarian function reconstruction have come to gratifying results.
  
  
  CONCLUSIONS
  Ovarian function reconstruction has a potential clinical value and provides a promising future.
authors.affiliation: Department of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhu
authors.forename: Mei
authors.initials: M
authors.lastname: Hou
authors.forename: Nie
authors.initials: N
authors.lastname: Xu
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D016649:Primary Ovarian Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D020127:Recovery of Function