title: Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia.
abstract: OBJECTIVE
  The purpose of the present study was to examine the extent of the effects of psychopathological symptoms and cognitive function on quality of life (QOL) in patients with chronic schizophrenia.
  
  
  METHODS
  Data were obtained using the Japanese Schizophrenia Quality of Life Scale (JSQLS), Positive and Negative Syndrome Scale (PANSS), Wisconsin Card-Sorting Test (WCST) Keio version, and Continuous Performance Test (CPT) for 52 schizophrenia patients.
  
  
  RESULTS
  Stepwise regression analysis showed that PANSS depression/anxiety factors predicted JSQLS psychosocial conditions and motivation/energy, and that WCST Categories Achieved predicted JSQLS symptoms/side-effects.
  
  
  CONCLUSIONS
  Psychopathological symptoms and cognitive function affect subjective QOL in patients with schizophrenia. If the final goal is treatment that improves QOL in a manner that patients themselves are aware of, clinicians probably need to consider a treatment strategy that improves depression/anxiety symptom.
authors.affiliation: Department of Psychiatry, Nagoya University, Graduate School of Medicine, Aichi, Japan. omh-psy@omh.ogaki.gifu.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Tomida
authors.forename: Nagahide
authors.initials: N
authors.lastname: Takahashi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Saito
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Maeno
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Iwamoto
authors.forename: Keizo
authors.initials: K
authors.lastname: Yoshida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kimura
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Iidaka
authors.forename: Norio
authors.initials: N
authors.lastname: Ozaki
mesh_terms: D000328:Adult; D001007:Anxiety / Q000150:complications / Q000523:psychology; D001288:Attention / Q000502:physiology; D002908:Chronic Disease; D003071:Cognition / Q000502:physiology*; D003863:Depression / Q000150:complications / Q000523:psychology; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012044:Regression Analysis; D012565:Schizophrenic Psychology