title: [Correlation of some biochemical and coagulological parameters in carotid atherosclerosis].
abstract: It has been established positive correlation of the degree of stenosis and intima-media thickness of carotid arteries with the following biochemical parameters: total cholesterol, LDL cholesterol, Apo-B, Lp(a), triglycerides, hs-C-reactive protein(CRP), interleukines (IL-1beta and IL-6), fibrinogen, D-dimers. Negative correlation was stated with respect to HDL cholesterol, Apo-A-1, protein C. Relation between the parameters of the blood lipid spectre, proteins and mediators of inflammation as well as those of hemostasis enables us to approach pathophysiological mechanisms of carotid atherosclerosis, define the processes of inflammation and atherosclerosis.
authors.forename: M V
authors.initials: MV
authors.lastname: Akhvlediani
authors.forename: E O
authors.initials: EO
authors.lastname: Vorob'eva
authors.forename: M G
authors.initials: MG
authors.lastname: Emukhvari
authors.forename: N A
authors.initials: NA
authors.lastname: Sharashidze
authors.forename: S B
authors.initials: SB
authors.lastname: Kupreishvili
mesh_terms: D002340:Carotid Artery Diseases / Q000097:blood* / Q000175:diagnosis / Q000276:immunology; D016893:Carotid Stenosis / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D005260:Female; D006801:Humans; D053583:Interleukin-1beta / Q000276:immunology; D015850:Interleukin-6 / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011516:Prothrombin / Q000378:metabolism*; D013925:Thromboplastin / Q000378:metabolism*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D053583:Interleukin-1beta; D015850:Interleukin-6; D011516:Prothrombin; D013925:Thromboplastin