An anesthesiologist with an allergy to multiple neuromuscular blocking drugs: a new occupational hazard.
We report a case of a final-year anesthesiology trainee who developed a severe allergic reaction to cutaneous exposure of succinylcholine. Intradermal testing was strongly positive to succinylcholine and all the aminosteroid neuromuscular blocking drugs (NMBDs). Specific immunoglobulin E to succinylcholine was also strongly positive. This unusual case of an anesthesiologist acquiring an allergy to an NMBD through occupational exposure has a significant effect on his practice of anesthesia. However, by avoiding operating rooms with a high usage of NMBDs and by wearing personal protective equipment, the anesthesiologist has worked in clinical anesthesia without incident.
Newman
Matthew J
MJ
Department of Women's Anaesthesia, Women's and Children's Hospital, North Adelaide, SA 5006, Australia. matthew.newman@health.sa.gov.a
Goel
Pooja
P
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced; D000776:Anesthesiology / Q000193:education; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007396:Internship and Residency; D007428:Intradermal Tests; D008297:Male; D009466:Neuromuscular Blocking Agents / Q000276:immunology*; D016273:Occupational Exposure; D013390:Succinylcholine / Q000276:immunology
D009466:Neuromuscular Blocking Agents; D007073:Immunoglobulin E; D013390:Succinylcholine