title: Treatment of class III multiple gingival recessions: a randomized-clinical trial.
abstract: BACKGROUND
  The aim of this controlled randomized split-mouth study was to evaluate whether a modified tunnel/connective tissue graft (CTG) technique - enamel matrix derivative (EMD) combination will improve the treatment of multiple class III recession when compared with the same technique alone.
  
  
  METHODS
  Twenty healthy subjects with a mean age of 31.7 years, were enrolled for the trial in a university periodontal clinic. Patients with at least three adjacent gingival recessions on both sides of the mouth were treated with a modified tunnel/CTG technique. On the test side, an EMD was used in addition. Clinical parameters were measured at baseline, 28 days, 3, 6 and 12 months after the surgery. Results are presented at the subject level.
  
  
  RESULTS
  The mean root coverage from baseline to 1 year post-surgery was 82% for the test group and 83% for the control group. Complete root coverage was achieved at 1 year in eight (38%) of the 20 surgeries (experimental and control group).
  
  
  CONCLUSIONS
  One-year results indicate that the modified tunnel/CTG technique is predictable for the treatment of multiple class III recession-type defects. The addition of EMD does not enhance the mean clinical outcomes.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, University of Szeged, Szeged, Hungary. sofiaaroca@mac.com
authors.forename: Sofia
authors.initials: S
authors.lastname: Aroca
authors.forename: Tibor
authors.initials: T
authors.lastname: Keglevich
authors.forename: Dimitris
authors.initials: D
authors.lastname: Nikolidakis
authors.forename: Istvan
authors.initials: I
authors.lastname: Gera
authors.forename: Katalin
authors.initials: K
authors.lastname: Nagy
authors.forename: Robert
authors.initials: R
authors.lastname: Azzi
authors.forename: Daniel
authors.initials: D
authors.lastname: Etienne
mesh_terms: D000328:Adult; D003238:Connective Tissue / Q000637:transplantation; D003746:Dental Enamel Proteins / Q000627:therapeutic use; D003774:Dental Plaque Index; D005500:Follow-Up Studies; D005881:Gingiva / Q000637:transplantation; D005889:Gingival Recession / Q000145:classification / Q000601:surgery*; D005893:Gingivoplasty / Q000379:methods; D006801:Humans; D017622:Periodontal Attachment Loss / Q000145:classification; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000145:classification; D013524:Surgical Flaps / Q000473:pathology; D013536:Suture Techniques; D014092:Tooth Root / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins