Phenacetin isolated from Bursera grandifolia, a herbal remedy with antipyretic properties.
Bursera grandifolia and other related species have been used in traditional herbal medicine in Mexico and other Latin American countries for their analgesic, antipyretic and anti-inflammatory properties. From the chloroform extract of leaves of B. grandifolia, a substance was isolated and identified as phenacetin, a well known compound with widely tested analgesic and antipyretic properties. The structural identity of the compound was elucidated on the basis of chemical and spectroscopic evidence and by comparison with an authentic sample.
Velázquez
Francisco
F
Departamento de Madera, Celulosa y Papel, CUCEI, Universidad de Guadalajara, Km 15.5, Carretera Guadalajara-Nogales, Guadalajara, Jalisco, Mexico 45020.
Manríquez
Ricardo
R
Maya
Leticia
L
Barrientos
Lucia
L
López-Dellamary
Fernando
F
D018712:Analgesics, Non-Narcotic / Q000737:chemistry* / Q000302:isolation & purification; D031233:Bursera / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D008800:Mexico; D010615:Phenacetin / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D028321:Plant Preparations / Q000032:analysis
D018712:Analgesics, Non-Narcotic; D028321:Plant Preparations; D010615:Phenacetin