[Efficacy of treatments on vision-related quality of life in patients with diabetic retinopathy].
OBJECTIVE
To evaluate changes in the vision-related quality of life in patients with diabetic retinopathy with the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25). Patients were categorized into three groups : without treatment, receiving pan-retinal photocoagulation, and those who had vitrectomy.


METHODS
Altogether 327 patients (131 without treatment, [observation group]; 60 receiving pan-retinal photocoagulation, [photocoagulation group]; and 136 patients who had vitrectomy, [vitrectomy group]). The VFQ-25 was recorded at the time of entry and 1 year later. The VFQ-25 score was compared between the time of entry and 1 year later for each group and among the three groups at both the time of entry and 1 year later.


RESULTS
VFQ-25 scores (mean +/- standard deviations) at the time of entry and 1 year later were 91.3 +/- 7.8 and 92.2 +/- 7.8 in the observation group, 80.7 +/- 15.7 and 77.6 +/-19.1 in the photocoagulation group, and 67.4 +/-17.3 and 75.4 +/- 17.5 in the vitrectomy group. VFQ-25 scores in the observation group and in the photocoagulation group did not change statistically between the time of entry and 1 year later (p = 0.113, 0.169, respectively), while the score of the vitrectomy group increased statistically (p < 0.001). In addition, although VFQ-25 scores were statistically significant among the three groups at the time of entry (p < 0.05), the scores 1 year later were not statistically different between the photocoagulation group and vitrectomy group.


CONCLUSIONS
These results suggest that vitrectomy for diabetic retinopathy may be effective in increasing the quality of life of patients with diabetic retinopathy.
Emi
Kazuyuki
K
Osaka Rosai Hospital Clinical Research Center for Occupational Sensory Organ Disability, Japan. kazuemi@orh.go.jp
Ikeda
Toshihide
T
Bando
Hajime
H
Sato
Shigeru
S
Morita
Shin-Ichi
S
Oyagi
Tomohito
T
Sato
Tatsuhiko
T
Sawada
Kosaku
K
Oura
Yoshihito
Y
Ueno
Chikako
C
D003930:Diabetic Retinopathy / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008028:Light Coagulation; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D016896:Treatment Outcome; D014785:Vision, Ocular; D014821:Vitrectomy