Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia.
OBJECTIVE
The purpose of the present study was to examine the extent of the effects of psychopathological symptoms and cognitive function on quality of life (QOL) in patients with chronic schizophrenia.


METHODS
Data were obtained using the Japanese Schizophrenia Quality of Life Scale (JSQLS), Positive and Negative Syndrome Scale (PANSS), Wisconsin Card-Sorting Test (WCST) Keio version, and Continuous Performance Test (CPT) for 52 schizophrenia patients.


RESULTS
Stepwise regression analysis showed that PANSS depression/anxiety factors predicted JSQLS psychosocial conditions and motivation/energy, and that WCST Categories Achieved predicted JSQLS symptoms/side-effects.


CONCLUSIONS
Psychopathological symptoms and cognitive function affect subjective QOL in patients with schizophrenia. If the final goal is treatment that improves QOL in a manner that patients themselves are aware of, clinicians probably need to consider a treatment strategy that improves depression/anxiety symptom.
Tomida
Kenji
K
Department of Psychiatry, Nagoya University, Graduate School of Medicine, Aichi, Japan. omh-psy@omh.ogaki.gifu.jp
Takahashi
Nagahide
N
Saito
Shinichi
S
Maeno
Nobuhisa
N
Iwamoto
Kunihiro
K
Yoshida
Keizo
K
Kimura
Hiroyuki
H
Iidaka
Tetsuya
T
Ozaki
Norio
N
D000328:Adult; D001007:Anxiety / Q000150:complications / Q000523:psychology; D001288:Attention / Q000502:physiology; D002908:Chronic Disease; D003071:Cognition / Q000502:physiology*; D003863:Depression / Q000150:complications / Q000523:psychology; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012044:Regression Analysis; D012565:Schizophrenic Psychology