Magnetoencephalographic characteristics of psychosis in temporal lobe epilepsy.
To test the hypothesis that some particular magnetoencephalographic findings characterize psychosis manifesting in temporal lobe epilepsy (TLE) patients, the authors performed statistical analyses on the correlation between a history of psychosis and four magnetoencephalographic spike-dipole patterns, namely, left and right inferotemporal-horizontal (IH) and superotemporal-vertical (SV) types. Fifty-seven patients with TLE were studied, 16 of whom had a history of psychosis. Of the four types of spike-dipoles, only left SV type showed a strong correlation with psychosis, suggesting that dysfunction of the left temporal neocortex specifically contributes to the manifestation of psychotic symptoms in TLE patients.
Fukao
Kenjiro
K
Department of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shôgoin-kawahara-chô, Sakyo-ku, Kyoto City 606-8507, Japan. fukao@kuhp.kyoto-u.ac.jp
Inoue
Yushi
Y
Yagi
Kazuichi
K
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D009415:Nerve Net / Q000503:physiopathology*; D018579:Patient Selection; D011618:Psychotic Disorders / Q000150:complications / Q000503:physiopathology*; D012720:Severity of Illness Index