title: Intraoperative laryngeal nerve monitoring during thyroidectomy.
abstract: OBJECTIVE
  To determine whether nerve integrity monitor testing during thyroidectomy predicts recurrent laryngeal nerve (RLN) function after surgery.
  
  
  METHODS
  Prospective cohort outcomes study
  
  
  METHODS
  The study included 210 consecutive patients with thyroid abnormalities who underwent thyroidectomy.
  
  
  METHODS
  All patients were intraoperatively monitored with a nerve integrity monitoring system (Xomed NIM II; Medtronic Inc, Fridley, Minnesota), and their vocal cord function was assessed with fiberoptic laryngoscopy before and after surgery. Normal and impaired vocal cord function were compared using an independent t test with respect to postoperative vocal cord mobility, length of the RLN dissection, and the minimum stimulus needed to generate a response at the completion of surgery.
  
  
  RESULTS
  There was a statistically significant difference between the stimulus in milliamperes required to stimulate normal vs abnormal functioning nerves at the completion of the procedure at the cricoarytenoid joint (P = .02) and at the distal end of the RLN dissection (P < .01). A greater length of dissected nerve was associated with normal vocal cord function; however, it was not statistically significant (P = .07).
  
  
  CONCLUSIONS
  These data suggest that an RLN that responds at lower-intensity stimulation (</=0.5 mA) at the end of thyroid surgery is associated with normal vocal cord mobility.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA. kdonnellan@ent.umsmed.edu
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Donnellan
authors.forename: Karen T
authors.initials: KT
authors.lastname: Pitman
authors.forename: C Ron
authors.initials: CR
authors.lastname: Cannon
authors.forename: William H
authors.initials: WH
authors.lastname: Replogle
authors.forename: Jon D
authors.initials: JD
authors.lastname: Simmons
mesh_terms: D015331:Cohort Studies; D004558:Electric Stimulation; D006801:Humans; D007823:Laryngeal Nerves / Q000502:physiology*; D007828:Laryngoscopy; D016343:Monitoring, Intraoperative / Q000295:instrumentation / Q000379:methods*; D011446:Prospective Studies; D012009:Recurrent Laryngeal Nerve / Q000502:physiology; D061226:Recurrent Laryngeal Nerve Injuries; D013959:Thyroid Diseases / Q000601:surgery; D013965:Thyroidectomy; D014827:Vocal Cords / Q000502:physiology*