Antimicrobial efficacy assessment of multi-use solution to disinfect hydrophilic contact lens, in vitro.
OBJECTIVE
To evaluate the efficacy of disinfecting solutions in hydrophilic contact lenses (CL).


METHODS
Two multi-use solutions denominated solution A (0.001% polyquaternium-1 and 0.0005% myristamidopropyl dimethylamine) and solution B (0.0001% polyaminopropyl biguanide) were used. The solutions were tested in hydrophilic contact lenses infected with Pseudomonas aeruginosa (ATCC27583), Staphylococcus epidermidis (ATCC1226), Klebsiella pneumoniae (ATCC13883), Staphylococcus aureus (ATCC25923) and Candida albicans (ATCC 10231) and the decrease in microorganisms growth after the hydrophilic contact lenses were cleaned with the respective solutions was verified. The manufacture's instructions were followed.


RESULTS
A decrease of 90% of Pseudomonas aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus, Candida albicans and a decrease 100% of Klebsiella pneumoniae was observed.


CONCLUSIONS
The solutions decreased the amount of microorganisms tested.
Lui
Aline Cristina Fioravanti
AC
Departamento de Oftalmologia, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil. acflui@yahoo.com.br
Netto
Adamo Lui
AL
Silva
Cely Barreto da
CB
Hida
Richard
R
Mendes
Thais Sousa
TS
Lui
Giovana Arlene Fioravanti
GA
Gemperli
Daniela Barbosa
DB
Vital
Enderson Dantas
ED
D000818:Animals; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D001645:Biguanides / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D015169:Colony Count, Microbial; D018639:Contact Lens Solutions / Q000494:pharmacology*; D003263:Contact Lenses, Hydrophilic / Q000382:microbiology*; D004202:Disinfectants / Q000494:pharmacology*; D007709:Klebsiella / Q000187:drug effects / Q000254:growth & development; D011108:Polymers / Q000494:pharmacology; D011437:Propylamines / Q000494:pharmacology / Q000592:standards; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000254:growth & development
D001645:Biguanides; D018639:Contact Lens Solutions; D004202:Disinfectants; D011108:Polymers; D011437:Propylamines; C064420:polyaminopropylbiguanide; C058655:polyquaternium 1; C401661:myristamidopropyl dimethylamine