title: Silver(I)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions.
abstract: Silver(I) salts mediated stereospecific transformation of optically active propargylamines to axially chiral allenes with excellent enantioselectivities (17 examples with 96-99% ee; one substrate with 91% ee) without subsequent racemization.
authors.affiliation: Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
authors.forename: Vanessa Kar-Yan
authors.initials: VK
authors.lastname: Lo
authors.forename: Cong-Ying
authors.initials: CY
authors.lastname: Zhou
authors.forename: Man-Kin
authors.initials: MK
authors.lastname: Wong
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che
mesh_terms: D000466:Alkadienes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D008872:Microwaves; D010293:Pargyline / Q000031:analogs & derivatives / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000466:Alkadienes; D011437:Propylamines; C009054:propargylamine; D012834:Silver; C025947:propadiene; D010293:Pargyline