[Advances in molecular genetic study of myopia].
Myopia is an important cause of blindness, in which an image is focused in front of the retina. Genetic factors have been implicated in the pathogenesis of myopia. Based on the molecular genetic study, some genetic loci linked to myopia have been mapped, but no disease-causing gene has been identified. Here authors review the genetic study on myopia, including gene mapping and candidate gene screening.
Zhang
Ding-ding
DD
Center for Molecular Genetics, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, Chengdu, Sichuan, 610072 P.R. China. zdd101@hotmail.com
Yang
Zheng-lin
ZL
D000818:Animals; D002874:Chromosome Mapping; D002877:Chromosomes, Human / Q000235:genetics; D005820:Genetic Testing; D006801:Humans; D009216:Myopia / Q000235:genetics*