title: Mathematical modelling of respiratory syncytial virus (RSV): vaccination strategies and budget applications.
abstract: We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of children aged <1 year that will be hospitalized in the following years in Valencia are presented using this model. Results are applied to estimate the regional cost of paediatric hospitalizations and to perform a cost-effectiveness analysis of possible vaccination strategies.
authors.affiliation: Instituto de Matemática Multidisciplinar, Universidad Politécnica de Valencia, 46022, Valencia, Spain. luiacrod@imm.upv.es
authors.forename: L
authors.initials: L
authors.lastname: Acedo
authors.forename: J
authors.initials: J
authors.lastname: Díez-Domingo
authors.forename: J-A
authors.initials: JA
authors.lastname: Moraño
authors.forename: R-J
authors.initials: RJ
authors.lastname: Villanueva
mesh_terms: D002017:Budgets; D003362:Cost-Benefit Analysis; D004196:Disease Outbreaks / Q000517:prevention & control; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008954:Models, Biological; D018357:Respiratory Syncytial Virus Infections / Q000191:economics / Q000453:epidemiology* / Q000517:prevention & control; D022261:Respiratory Syncytial Virus Vaccines / Q000191:economics; D012621:Seasons; D013030:Spain / Q000453:epidemiology
chemical_list: D022261:Respiratory Syncytial Virus Vaccines