Effects of subchronic simazine exposure on some biometric, biochemical, hematological and histopathological parameters of common carp (Cyprinus carpio L.).
OBJECTIVE
This study assessed the subchronic effects of a triazine compound, simazine, on common carp (Cyprinus carpio L.) though, via by means of biometric, biochemical, hematological, and histological examination.


METHODS
One-year-old fish were exposed to simazine at four concentrations, 0.06, (reported concentration in Czech rivers), 4, 20, and 50 microg L-1 for 28 days and compared to carp in a non-treated control group.


RESULTS
Exposure of fish to simazine at 0.06 microg L-1 had no effect on measured parameters. However, exposure to simazine at the concentrations of 4, 20, 50 microg L-1 showed significant differences in biochemical, hematological, and histopathological profiles of fish compared to controls.


CONCLUSIONS
Our data suggest that simazine in the recorded environmental concentration 0.06 microg L-1 had no effect on common carp. Subchronic exposure to 4, 20, and 50 microg L-1 of simazine was associated with alterations in biochemical and hematological indices and in fish organ tissues.
Velisek
Jozef
J
Research Institute of Fish Culture and Hydrobiology Vodnany, University of South Bohemia, Ceske Budejovice, Czech Republic. velisek@vurh.jcu.cz
Stastna
Kamila
K
Sudova
Eliska
E
Turek
Jan
J
Svobodova
Zdenka
Z
D000818:Animals; D002347:Carps / Q000502:physiology*; D018153:Czech Republic; D004305:Dose-Response Relationship, Drug; D006540:Herbicides / Q000008:administration & dosage / Q000633:toxicity*; D011897:Random Allocation; D045483:Rivers; D012839:Simazine / Q000008:administration & dosage / Q000633:toxicity*; D018675:Toxicity Tests; D014873:Water Pollutants / Q000008:administration & dosage / Q000633:toxicity
D006540:Herbicides; D014873:Water Pollutants; D012839:Simazine