title: Polypeptide-polymer bioconjugates.
abstract: Creating bioconjugates by combining polymers with peptides and proteins is an emerging multidisciplinary field of research that has enjoyed increased attention within the scientific community. This critical review provides an overview of the strategies employed for the construction of these materials and will highlight the underlying synthetic methods used. This review is therefore relevant for chemists, material scientists and chemical biologists facing the challenge of constructing polypeptide-polymer bioconjugates in a controlled fashion (269 references).
authors.affiliation: Bio-Organic Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
authors.forename: Luiz A
authors.initials: LA
authors.lastname: Canalle
authors.forename: Dennis W P M
authors.initials: DW
authors.lastname: Löwik
authors.forename: Jan C M
authors.initials: JC
authors.lastname: van Hest
mesh_terms: D000818:Animals; D006801:Humans; D010455:Peptides / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D010455:Peptides; D011108:Polymers; D011506:Proteins