"Smart" diblock copolymers as templates for magnetic-core gold-shell nanoparticle synthesis.
We report a new strategy for synthesizing temperature-responsive gamma-Fe(2)O(3)-core/Au-shell nanoparticles (Au-mNPs) from diblock copolymer micelles. The amphiphilic diblock copolymer chains were synthesized using reversible addition-fragmentation chain-transfer (RAFT) with a thermally responsive "smart" poly(N-isopropylacrylamide) (pNIPAAm) block and an amine-containing poly(N,N-dimethylaminoethylacrylamide) (DMAEAm) block that acted as a reducing agent during gold shell formation. The Au-mNPs reversibly aggregated upon heating the solution above the transition temperature of pNIPAAm, resulting in a red-shifted localized surface plasmon resonance.
Nash
Michael A
MA
Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Lai
James J
JJ
Hoffman
Allan S
AS
Yager
Paul
P
Stayton
Patrick S
PS
D000178:Acrylamides / Q000737:chemistry; D000180:Acrylic Resins / Q000737:chemistry; D001709:Biotechnology / Q000379:methods; D006046:Gold / Q000737:chemistry*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry*; D008823:Micelles; D046529:Microscopy, Electron, Transmission / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D011108:Polymers / Q000737:chemistry; D020349:Surface Plasmon Resonance; D013696:Temperature
D000178:Acrylamides; D000180:Acrylic Resins; D008823:Micelles; D011108:Polymers; C052970:poly-N-isopropylacrylamide; D006046:Gold