title: Comparative analysis of Micrococcus luteus isolates from blood cultures of patients with pulmonary hypertension receiving epoprostenol continuous infusion.
abstract: During the period 2002-2008, at the National Cardiovascular Center, Osaka, 28 Micrococcus luteus isolates and one Kocuria spp. isolate were obtained from blood cultures of pulmonary hypertension (PH) patients who were receiving continuous infusion therapy with epoprostenol. Pulsed-field gel electrophoresis patterns of the isolates were unrelated, suggesting that the infections had multiple origins. The preparation of epoprostenol solution by patients themselves was thought to be a risk factor.
authors.affiliation: Department of Clinical Laboratory, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka, 565-8565, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Hirata
authors.forename: Makoto
authors.initials: M
authors.lastname: Sata
authors.forename: Yuko
authors.initials: Y
authors.lastname: Makiuchi
authors.forename: Keita
authors.initials: K
authors.lastname: Morikane
authors.forename: Akihito
authors.initials: A
authors.lastname: Wada
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Okabe
authors.forename: Hitonobu
authors.initials: H
authors.lastname: Tomoike
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage; D002408:Catheters, Indwelling / Q000382:microbiology; D004340:Drug Contamination; D016521:Electrophoresis, Gel, Pulsed-Field; D011464:Epoprostenol / Q000008:administration & dosage*; D016908:Gram-Positive Bacterial Infections / Q000097:blood* / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000097:blood / Q000188:drug therapy / Q000382:microbiology*; D007262:Infusions, Intravenous; D016982:Micrococcus luteus / Q000235:genetics / Q000302:isolation & purification*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage
chemical_list: D000959:Antihypertensive Agents; D010975:Platelet Aggregation Inhibitors; D011464:Epoprostenol