title: The dangers of transcription.
abstract: Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.
authors.affiliation: Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany. stephan.mathas@charite.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Mathas
authors.forename: Tom
authors.initials: T
authors.lastname: Misteli
mesh_terms: D053903:DNA Breaks, Double-Stranded; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D011944:Receptors, Androgen / Q000378:metabolism; D014178:Translocation, Genetic
chemical_list: D011944:Receptors, Androgen