title: Endothelial keratoplasty: endothelial cell loss after deep lamellar endothelial keratoplasty with retention of an open-loop anterior chamber intraocular lens.
abstract: OBJECTIVE
  To prospectively assess the impact of a retained open-loop anterior chamber intraocular lens (ACIOLs) on endothelial cell loss after deep lamellar endothelial keratoplasty (DLEK).
  
  
  METHODS
  Prospectively gathered central endothelial cell densities of eyes with open-loop ACIOLs after DLEK were examined at 6 months, 1 year, and 2 years.
  
  
  RESULTS
  Nine eyes with an open-loop ACIOL were examined. Mean endothelial cell loss was 37% at 6 months (n = 9, P = 0.001), 36% at 1 year (n = 6, P = 0.001), and 41%, at 2 years (n = 5, P = 0.002) after surgery.
  
  
  CONCLUSIONS
  Postoperative endothelial cell loss over the first 2 years in this small series of patients undergoing DLEK with retention of an open-loop ACIOL may be greater in the first 6-12 months but similar at 2 years when compared with that found in the literature for the DLEK procedure.
authors.affiliation: Department of Ophthalmology, Legacy Health Systems, Devers Eye Institute, Portland, OR 97210, USA.
authors.forename: Edwin S
authors.initials: ES
authors.lastname: Chen
authors.forename: Mark A
authors.initials: MA
authors.lastname: Terry
authors.forename: Neda
authors.initials: N
authors.lastname: Shamie
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Friend
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000601:surgery*; D002452:Cell Count; D003316:Corneal Diseases / Q000601:surgery; D055954:Corneal Endothelial Cell Loss / Q000175:diagnosis / Q000209:etiology*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D004728:Endothelium, Corneal / Q000473:pathology* / Q000601:surgery; D005260:Female; D006085:Graft Survival; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies