title: [Dendritic cells in hypertrophied adenoid at children with otitis media with effusion].
abstract: BACKGROUND
  The adenoids are organized as lymphoepithelial structures that play an important role in protecting both the upper respiratory and alimentary tract regions. This functions requires dendritic cells (DC) which are one of the major populations of immune cells. Due to the presence of specific receptors (DC) are able to respond to both intra- and extracellular antigens. Dendritic cells activating immunological response in tonsil contribute formation immunologic competent cells on necessity of rolling inflammatory process in middle ear.
  
  
  OBJECTIVE
  An investigation was executed in hypertrophied adenoids with or without otitis media with effusion.
  
  
  METHODS
  By flow cytometry percentage of CD11c+ myeloid DC and 123+ plasmacytoid DC in hypertrophied adenoid and hypertrophied adenoid and otitis media with effusion was analyzed.
  
  
  RESULTS
  The percentage of CD11c+ myeloid DC and 123+ plasmacytoid DC was similar in hypertrophied adenoid and otitis media with effusion compored to the control group.
  
  
  CONCLUSIONS
  Our data show that part of dendritic cells has not on course of inflammatory process influence rolling in middle ear.
authors.affiliation: Zakład Laboratoryjnej Diagnostyki Pediatrycznej Uniwersytetu Medycznego w Białymstoku. zelazowskab@wp.pl
authors.forename: Beata
authors.initials: B
authors.lastname: Zelazowska-Rutkowska
authors.forename: Karol
authors.initials: K
authors.lastname: Ratomski
authors.forename: Jolanta
authors.initials: J
authors.lastname: Wysocka
authors.forename: Edwina
authors.initials: E
authors.lastname: Kasprzycka
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Hassmann-Poznańska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mrugacz
mesh_terms: D000234:Adenoids / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D018941:Antigens, CD19 / Q000378:metabolism; D001402:B-Lymphocytes / Q000378:metabolism; D018956:CD5 Antigens / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003713:Dendritic Cells / Q000378:metabolism*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D006984:Hypertrophy / Q000276:immunology; D008297:Male; D010034:Otitis Media with Effusion / Q000276:immunology* / Q000601:surgery*; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric
chemical_list: D018941:Antigens, CD19; D018956:CD5 Antigens