Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins.
A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.
Payne
Richard J
RJ
School of Chemistry, The University of Sydney, Sydney, Australia. payne@chem.usyd.edu.au
Wong
Chi-Huey
CH
D000595:Amino Acid Sequence; D002241:Carbohydrates / Q000737:chemistry; D006020:Glycopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D006023:Glycoproteins / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D008969:Molecular Sequence Data; D013438:Sulfhydryl Compounds / Q000737:chemistry
D002241:Carbohydrates; D006020:Glycopeptides; D006023:Glycoproteins; D013438:Sulfhydryl Compounds