title: [Large-vessel granulomatous vasculitis during the course of sarcoidosis: Takayasu's arteritis?].
abstract: BACKGROUND
  Vascular involvement in sarcoidosis is very rare and is characterized by preferential involvement of large vessels similar to that observed in Takayasu's disease. Distinguishing between these two diseases is often difficult and constitutes a diagnostic pitfall. The association between sarcoidosis and Takayasu's arteritis is not coincidental and a common physiopathological factor may exist; it suggests a possible aetiopathogenetic relationship between sarcoidosis and Takayasu's arteritis and casts doubt on whether this form of vasculitis is a disease in its own right or simply a syndrome caused by other diseases.
  
  
  METHODS
  We report the case of a man with a 10-year history of cutaneous and pulmonary sarcoidosis who developed ischaemia of the right upper limb evocative of Takayasu's arteritis. The patient was successfully treated with oral steroids and methotrexate.
  
  
  CONCLUSIONS
  This case prompts discussion about the relationship between Takayasu's disease and sarcoidosis. Physicians should be aware of the possible occurrence of granulomatous arteritis during the course of sarcoidosis which requires a special work-up.
authors.affiliation: Service de dermatologie, hôpital Purpan, CHU de Toulouse, 31059 Toulouse, France.
authors.forename: C
authors.initials: C
authors.lastname: Vaurs
authors.forename: A
authors.initials: A
authors.lastname: Ammoury
authors.forename: N
authors.initials: N
authors.lastname: Cordel
authors.forename: L
authors.initials: L
authors.lastname: Lamant
authors.forename: X
authors.initials: X
authors.lastname: Chaufour
authors.forename: C
authors.initials: C
authors.lastname: Paul
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications*; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D012871:Skin Diseases / Q000150:complications; D013625:Takayasu Arteritis / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D008727:Methotrexate