title: Enzyme logic gate associated with a single responsive microparticle: scaling biocomputing to microsize systems.
abstract: A microsize biocomputing system based on enzyme logic processing biochemical signals was developed. Optical transduction of pH signals generated in situ by the enzyme OR logic gate was achieved with the use of a single optode microparticle.
authors.affiliation: Department of Chemistry, and NanoBio Laboratory, Oregon State University, Corvallis, OR 97331, USA.
authors.forename: Valeriya
authors.initials: V
authors.lastname: Bychkova
authors.forename: Alexey
authors.initials: A
authors.lastname: Shvarev
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Marcos
authors.initials: M
authors.lastname: Pita
authors.forename: Evgeny
authors.initials: E
authors.lastname: Katz
mesh_terms: D000818:Animals; D055162:Biocatalysis; D004950:Esterases / Q000737:chemistry* / Q000378:metabolism; D005949:Glucose Oxidase / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008904:Miniaturization; D010316:Particle Size; D013050:Spectrometry, Fluorescence; D013552:Swine; D014510:Urease / Q000737:chemistry* / Q000378:metabolism
chemical_list: D005949:Glucose Oxidase; D004950:Esterases; D014510:Urease