title: Sentinel node detection in head and neck malignancies: innovations in radioguided surgery.
abstract: Sentinel node mapping is becoming a routine procedure for staging of various malignancies, because it can determine lymph node status more precisely. Due to anatomical problems, localizing sentinel nodes in the head and neck region on the basis of conventional images can be difficult. New diagnostic tools can provide better visualization of sentinel nodes. In an attempt to keep up with possible scientific progress, this article reviews new and innovative tools for sentinel node localization in this specific area. The overview comprises a short introduction of the sentinel node procedure as well as indications in the head and neck region. Then the results of SPECT/CT for sentinel node detection are described. Finally, a portable gamma camera to enable intraoperative real-time imaging with improved sentinel node detection is described.
authors.affiliation: Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: Vermeeren
authors.forename: W M C
authors.initials: WM
authors.lastname: Klop
authors.forename: M W M
authors.initials: MW
authors.lastname: van den Brekel
authors.forename: A J M
authors.initials: AJ
authors.lastname: Balm
authors.forename: O E
authors.initials: OE
authors.lastname: Nieweg
authors.forename: R A
authors.initials: RA
authors.lastname: Valdés Olmos