title: webMGR: an online tool for the multiple genome rearrangement problem.
abstract: CONCLUSIONS
  The algorithm MGR enables the reconstruction of rearrangement phylogenies based on gene or synteny block order in multiple genomes. Although MGR has been successfully applied to study the evolution of different sets of species, its utilization has been hampered by the prohibitive running time for some applications. In the current work, we have designed new heuristics that significantly speed up the tool without compromising its accuracy. Moreover, we have developed a web server (webMGR) that includes elaborate web output to facilitate navigation through the results.
  
  
  BACKGROUND
  webMGR can be accessed via http://www.gis.a-star.edu.sg/~bourque. The source code of the improved standalone version of MGR is also freely available from the web site.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Genome Institute of Singapore, 60 Biopolis Street, #02-01, Genome, Singapore 138672.
authors.forename: Chi Ho
authors.initials: CH
authors.lastname: Lin
authors.forename: Hao
authors.initials: H
authors.lastname: Zhao
authors.forename: Sean Harry
authors.initials: SH
authors.lastname: Lowcay
authors.forename: Atif
authors.initials: A
authors.lastname: Shahab
authors.forename: Guillaume
authors.initials: G
authors.lastname: Bourque
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D015321:Gene Rearrangement / Q000235:genetics*; D016678:Genome; D020407:Internet; D010802:Phylogeny; D012984:Software; D026801:Synteny