title: Early cervical cancer managed by laparoscopy and conventional surgery: comparison of treatment results.
abstract: BACKGROUND
  The goal of this retrospective analysis was to compare the results of treatment in patients with early cervical cancer managed by laparoscopy with those for patients observed after laparotomy.
  
  
  METHODS
  The retrospective analysis was carried out with 22 patients operated on with total laparoscopic hysterectomy and 58 patients treated by abdominal hysterectomy. Patients with clinical tumor stage IA, IB1, or IIA were eligible for surgery. The main efficacy end point was disease-free survival evaluated by the Kaplan-Meier method. The survival curves were compared using log-rank tests. In addition, length of hospitalization, duration of surgery, and complication rate were compared. P < 0.05 was set as statistically significant.
  
  
  RESULTS
  Predicted 3-year disease-free survival rates in the "open surgery" and "laparoscopy" groups were 0.86 (standard deviation [SD], 0.049) and 0.82 (SD, 0.098), respectively (P = 0.53). Recurrence rate was 13.6% after laparoscopy and 12% in open surgery. In 2 patients, intraperitoneal spread occurred after laparoscopy. The operation time was longer and hospitalization shorter after laparoscopy.
  
  
  CONCLUSIONS
  The 3-year disease-free survival was similar in both groups. Total laparoscopic radical hysterectomy may be an option in early cervical cancer; however, the intraperitoneal spread in 2 patients compels a search for possible risk factors in patients managed by laparoscopy.
authors.affiliation: Gynecologic Oncology Department, Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland. sobiczewskipiotr@acn.waw.pl
authors.forename: Piotr
authors.initials: P
authors.lastname: Sobiczewski
authors.forename: Mariusz
authors.initials: M
authors.lastname: Bidzinski
authors.forename: Pawel
authors.initials: P
authors.lastname: Derlatka
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Panek
authors.forename: Anna
authors.initials: A
authors.lastname: Danska-Bidzinska
authors.forename: Leszek
authors.initials: L
authors.lastname: Gmyrek
authors.forename: Wojciech
authors.initials: W
authors.lastname: Michalski
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery*; D018288:Carcinoma, Small Cell / Q000556:secondary / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D010535:Laparoscopy; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*