title: [Application of PET in radiation oncology].
abstract: Positron emission tomography (PET), especially F-18 fluorodeoxyglucose (FDG)-PET, has been recently used to verify the target volume in radiation treatment planning (RTP) for malignancies. The utility of FDG-PET/CT in defining gross tumor volume (GTV) has been shown in many studies, and the target delineation by a fixed threshold of the maximum standardized uptake value (40-50%) is suggested to be useful in RTP for lung cancer, head and neck cancer, etc. But, the spatial resolution, sensitivity, and specificity of PET are not always enough to define the difference between the GTV and the clinical target volume(CTV). Furthermore, FDG-PET is frequently used in the clinical staging before the treatment, and is also applied to the response evaluation after the treatment. This review focuses on the developing applications of PET in radiation oncology.
authors.affiliation: Dept. of Radiation Oncology, Nara Medical University, Nara, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Hasegawa
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Uto
authors.forename: Isao
authors.initials: I
authors.lastname: Asakawa
authors.forename: Chikae
authors.initials: C
authors.lastname: Kajitani
authors.forename: Emiko
authors.initials: E
authors.lastname: Katayama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okada
authors.forename: Shigeto
authors.initials: S
authors.lastname: Hontsu
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Tamamoto
mesh_terms: D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D049268:Positron-Emission Tomography; D011880:Radiotherapy Planning, Computer-Assisted