title: Long-term results of vaginal repairs with and without xenograft reinforcement.
abstract: OBJECTIVE
  The aim of this paper is to study if xenograft reinforcement of vaginal repair reduces recurrence of prolapse.
  
  
  METHODS
  Results 1-5 years after vaginal repair were studied in 41 cases with xenograft and in 82 matched controls without. Symptoms were evaluated by a validated questionnaire and anatomy by pelvic organ prolapse quantification (POPQ).
  
  
  RESULTS
  Significant more cases, 97% versus 81% controls, felt cured or much improved (p = 0.02); 11% of cases and 19% of controls had POP symptoms, POPQ > -1 was found in 31% cases and 24% controls. Defining recurrence as POPQ > -1 plus symptoms revealed recurrence in 3% of cases and 12% controls. None of the recurrence rates was significantly different for cases versus controls. No vaginal erosions were seen. Previous surgery was a significant risk factor with odds ratio 7.3 for another recurrence.
  
  
  CONCLUSIONS
  Recurrence rates defined by POPQ plus symptoms were low compared to literature. Xenograft reinforcement might improve results.
authors.affiliation: Department of Gynecology and Obstetrics, Herlev Hospital, University of Copenhagen, 2730 Herlev, Copenhagen, Denmark. lonemouritsen@newmail.dk
authors.forename: Lone
authors.initials: L
authors.lastname: Mouritsen
authors.forename: Manuela
authors.initials: M
authors.lastname: Kronschnabl
authors.forename: Gunnar
authors.initials: G
authors.lastname: Lose
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001684:Biological Dressings; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D014621:Vagina / Q000601:surgery*