[Evaluation of anti-inflammatory activity of extracts from Siberian plants].
Experimental investigations have shown that water-alcohol extracts from plants containing alkaloids (Aconitum baikalense, Aconitum septentrionale, Delphinium elatum L., Conium maculatum) and salicylic acid (Filipendula ulmaria, Salix viminalis, Fragaria vesca, Rubus idaeus) inhibited the development of main symptoms of inflammation, viz. exudation, pain, fever, to the same extent as non-steroidal anti-inflammatory agents. The substances studied in this work may be used to develop new efficient pharmacological preparations for the treatment of different inflammatory conditions associated with severe pain syndrome.
Nesterova
Iu V
IuV
Povet'eva
T N
TN
Aksinenko
S G
SG
Suslov
N I
NI
Gaĭdamovich
N N
NN
Nagorniak
Iu G
IuG
Popova
E V
EV
Kravtsova
S S
SS
Andreeva
T I
TI
D031841:Aconitum / Q000737:chemistry; D000470:Alkaloids / Q000032:analysis; D000818:Animals; D029982:Conium / Q000737:chemistry; D031882:Delphinium / Q000737:chemistry; D004195:Disease Models, Animal; D005260:Female; D031985:Fragaria / Q000737:chemistry; D007249:Inflammation / Q000188:drug therapy*; D008297:Male; D051379:Mice; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use*; D051381:Rats; D020156:Salicylic Acid / Q000032:analysis; D032108:Salix / Q000737:chemistry; D012800:Siberia; D016896:Treatment Outcome
D000470:Alkaloids; D010936:Plant Extracts; D020156:Salicylic Acid