Re-irradiation of metastatic spinal cord compression: a feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal.
When local recurrences arise within an irradiated region involving metastatic spinal cord compression, the dose limit to the spinal cord reduces the chance to re-treat the patient by 3D-conformational RT technique. The possibility of using volumetric modulated arc RT by RapidArc was evaluated for dose sparing at spinal cord level and preserving target coverage. A clinically satisfactory PTV coverage and dose sparing to the spinal cord were obtained. An upcoming trial on patients will provide clinical outcomes.
Mancosu
Pietro
P
IRCCS Istituto Clinico Humanitas, Radiation Oncology, Via Manzoni 56, 20098 Rozzano, Italy. pietro.mancosu@humanitas.it
Navarria
Piera
P
Bignardi
Mario
M
Cozzi
Luca
L
Fogliata
Antonella
A
Lattuada
Paola
P
Santoro
Armando
A
Urso
Gaetano
G
Vigorito
Sabrina
S
Scorsetti
Marta
M
D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D011874:Radiometry; D019233:Retreatment; D013117:Spinal Cord Compression / Q000209:etiology / Q000532:radiotherapy*; D016896:Treatment Outcome