title: [Cocaine-related gastric perforation].
abstract: Since the 1980s the abuse of cocaine has been -associated with gastroduodenal perforations in the United States. Here, we report the case of a 28-year-old man who came to our hospital with severe abdominal pain after smoking cocaine. Physical examination revealed generalised abdominal guarding. His X-ray did not show any free intraperitoneal air. However, there was a slightly elevated white blood cell count. Upon laparoscopic exploration of the abdomen, the -patient was found to have a generalised peritonitis secondary to a perforation of the prepyloric anterior wall. The operative procedure consisted of ulcer excision and primary closure with a pyloroplasty as well as an extensive abdominal irrigation after laparotomy.
authors.affiliation: St. Josefs Hospital Dortmund-Süd, Abteilung für Allgemein-, Viszeral- und Unfallchirurgie, Darmzentrum Ruhr, Dortmund, Deutschland. andrej.ring@ruhr-unibochum.de
authors.forename: A
authors.initials: A
authors.lastname: Ring
authors.forename: E
authors.initials: E
authors.lastname: Stein
authors.forename: J
authors.initials: J
authors.lastname: Stern
mesh_terms: D000006:Abdomen, Acute / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D003042:Cocaine / Q000633:toxicity*; D019970:Cocaine-Related Disorders / Q000150:complications*; D003937:Diagnosis, Differential; D003932:Heroin / Q000633:toxicity*; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D009294:Narcotics / Q000633:toxicity*; D010439:Peptic Ulcer Perforation / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D010538:Peritonitis / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery; D011708:Pylorus / Q000473:pathology / Q000601:surgery; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D014662:Vasoconstrictor Agents / Q000633:toxicity*
chemical_list: D009294:Narcotics; D014662:Vasoconstrictor Agents; D003932:Heroin; D003042:Cocaine