title: Reviewing the unsubstantiated claims for the methodological superiority of 'placebo' over 'active' controlled trials: reply to open peer commentaries.
authors.affiliation: University of Oxford, Centre for Evidence-Based Medicine, Old Road Campus, Oxford, United Kingdom. jeremy.howick@dphpc.ox.ac.uk
authors.forename: Jeremy
authors.initials: J
authors.lastname: Howick
mesh_terms: D018849:Controlled Clinical Trials as Topic / Q000941:ethics* / Q000379:methods*; D026690:Ethics, Clinical; D004992:Ethics, Medical; D032984:Ethics, Research; D006801:Humans; D028681:Moral Obligations; D009422:Nervous System Diseases / Q000188:drug therapy; D010817:Physician-Patient Relations / Q000941:ethics*; D015990:Placebo Effect; D010919:Placebos / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic / Q000941:ethics / Q000379:methods; D012107:Research Design; D035842:Research Subjects / Q000523:psychology; D035844:Researcher-Subject Relations / Q000941:ethics*; D018401:Sample Size; D012680:Sensitivity and Specificity
chemical_list: D010919:Placebos