title: Evaluating a marker's contribution to a nomogram: the GEMCaP example.
abstract: A postoperative nomogram developed in 1999 by Kattan et al. has been externally validated, but needs improvement. This tool predicts well but not perfectly. The Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) biomarkers hold promise for improving this tool; however, a larger data set that permits more involved analyses is needed.
authors.affiliation: Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195, USA. kattanm@ccf.org
authors.forename: Michael W
authors.initials: MW
authors.lastname: Kattan
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D018450:Disease Progression; D006801:Humans; D008297:Male; D015233:Models, Statistical; D049451:Nomograms; D011184:Postoperative Period; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D018570:Risk Assessment
chemical_list: D014408:Biomarkers, Tumor