[Large-vessel granulomatous vasculitis during the course of sarcoidosis: Takayasu's arteritis?].
BACKGROUND
Vascular involvement in sarcoidosis is very rare and is characterized by preferential involvement of large vessels similar to that observed in Takayasu's disease. Distinguishing between these two diseases is often difficult and constitutes a diagnostic pitfall. The association between sarcoidosis and Takayasu's arteritis is not coincidental and a common physiopathological factor may exist; it suggests a possible aetiopathogenetic relationship between sarcoidosis and Takayasu's arteritis and casts doubt on whether this form of vasculitis is a disease in its own right or simply a syndrome caused by other diseases.


METHODS
We report the case of a man with a 10-year history of cutaneous and pulmonary sarcoidosis who developed ischaemia of the right upper limb evocative of Takayasu's arteritis. The patient was successfully treated with oral steroids and methotrexate.


CONCLUSIONS
This case prompts discussion about the relationship between Takayasu's disease and sarcoidosis. Physicians should be aware of the possible occurrence of granulomatous arteritis during the course of sarcoidosis which requires a special work-up.
Vaurs
C
C
Service de dermatologie, hôpital Purpan, CHU de Toulouse, 31059 Toulouse, France.
Ammoury
A
A
Cordel
N
N
Lamant
L
L
Chaufour
X
X
Paul
C
C
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications*; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D012871:Skin Diseases / Q000150:complications; D013625:Takayasu Arteritis / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D008727:Methotrexate