Total synthesis of largamide H.
Total synthesis of largamide H has been completed, utilising the oxidative elimination reaction of enantiomerically pure 2-amino-3-(phenylselenyl)butanoic acid residues to stereospecifically install both (Z)- and (E)-2,3-dehydro-2-aminobutanoic moieties.
Liang
Shuo
S
Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, University Town of Shenzhen, Xili, Nanshan District, Shenzhen, China.
Xu
Zhengshuang
Z
Ye
Tao
T
D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D047630:Depsipeptides; D010456:Peptides, Cyclic; C547239:largamide H