Growth in Noonan syndrome.
Growth failure in Noonan syndrome is mainly postnatal of character and is dominated by slow maturation and late puberty. The postnatal early decline seems to be an intrinsic part of the syndrome. Reported adult heights are about -2 SD and are indicative of a secular trend.
Otten
B J
BJ
Department of Pediatric Endocrinology, Radboud University Nijmegen Medical Center, The Netherlands.
Noordam
C
C
D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005260:Female; D006128:Growth; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009634:Noonan Syndrome / Q000503:physiopathology*; D011627:Puberty
D013006:Growth Hormone