Ortho-C-H borylation of benzoate esters with bis(pinacolato)diboron catalyzed by iridium-phosphine complexes.
Iridium complexes generated from [Ir(OMe)(COD)](2) and tris[3,5-bis(trifluoromethyl)phenyl]phosphine efficiently catalyzed the ortho-C-H borylation of benzoate esters with bis(pinacolato)diboron in octane at 80 degrees C to produce the corresponding arylboronates in high yields with excellent regioselectivities.
Ishiyama
Tatsuo
T
Division of Chemical Process Engineering, Graduate School of Engineering, Hokkaido University, Sapporo 060-8628, Japan. ishiyama@eng.hokudai.ac.jp
Isou
Hironori
H
Kikuchi
Takao
T
Miyaura
Norio
N