title: The oncologic safety and functional preservation of supraglottic partial laryngectomy.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the appropriateness of the conservative surgery as the initial treatment of supraglottic cancer by the comparative study of supraglottic partial laryngectomy with radiation therapy.
  
  
  METHODS
  We analyzed 48 patients diagnosed as having supraglottic cancer who underwent supraglottic partial laryngectomy and 20 patients treated with radiation therapy as initial treatment from 1991 to 2005. Oncologic safety was evaluated by comparison of survival rates. Swallowing test was performed with videoesophagofluoroscopy under the category of the pharyngeal phase and the presence or absence of aspiration. Phonologic analysis was performed with acoustic waveform analysis and stroboscopy.
  
  
  RESULTS
  Positive resection margin was observed in 12 of the patients who received supraglottic partial laryngectomy (SPL), and its relationship with the primary subsite was evaluated. For the patients in stages I and II, the overall survival rate in each of the SPL group and the radiotherapy (RTx) group was 87% and 80%, respectively. For the patients in stages III and IV, the overall survival rate was 87% and 80%, respectively. On evaluation of swallowing and phonation function, no significant difference was noted between the SPL group and the RTx group.
  
  
  CONCLUSIONS
  This study suggests that for patients with supraglottic cancer, SPL provides acceptable survival, swallowing, and phonologic results in comparison with radiation therapy.
authors.affiliation: Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Je Young
authors.initials: JY
authors.lastname: Chun
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
authors.forename: Eun Chang
authors.initials: EC
authors.lastname: Choi
authors.forename: Hyung Kwon
authors.initials: HK
authors.lastname: Byeon
authors.forename: Jinsei
authors.initials: J
authors.lastname: Jung
authors.forename: Se-Heon
authors.initials: SH
authors.lastname: Kim
mesh_terms: D000368:Aged; D003679:Deglutition / Q000502:physiology*; D005471:Fluoroscopy; D005500:Follow-Up Studies; D005931:Glottis / Q000503:physiopathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008875:Middle Aged; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D049489:Stroboscopy; D016896:Treatment Outcome; D014741:Video Recording; D014833:Voice Quality / Q000502:physiology*