title: Necrotizing fasciitis secondary to bisphosphonate-induced osteonecrosis of the jaw.
abstract: Osteonecrosis of the jaw is an uncommon consequence of biphosphonate therapy. This has most commonly been a bone complication with little if any soft tissue involvement. An unusual case of necrotizing fasciitis with extensive soft tissue infection stemming from a prolonged case of osteonecrosis of the jaw presented. The management of this patient (aggressive surgical debridement and prolonged wound care) is reviewed as well as the review of the underlying processes.
authors.affiliation: Texas Tech University Health Sciences Center, Amarillo, TX, USA.
authors.forename: Dhave
authors.initials: D
authors.lastname: Setabutr
authors.forename: Nathan W
authors.initials: NW
authors.lastname: Hales
authors.forename: Greg A
authors.initials: GA
authors.lastname: Krempl
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary; D004164:Diphosphonates / Q000009:adverse effects*; D019115:Fasciitis, Necrotizing / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced* / Q000150:complications*; D010020:Osteonecrosis / Q000139:chemically induced* / Q000150:complications*
chemical_list: D004164:Diphosphonates