title: Cutaneous warts in children before and after renal transplantation.
abstract: Cutaneous warts occur in 3.9-4.9% of children in the UK. The incidence is increased in organ transplant recipients and may be increased in patients with chronic kidney disease (CKD), since uraemia reduces the immune system's function. We surveyed the records from our CKD and renal transplant clinic to ensure patients with warts were identified and appropriately treated. Data were collected by questionnaire. The presence of warts, location, treatment, levels of pain and emotional upset were recorded. Nine of 49 (18.4%) pre-transplantation patients (33 male, median age 12.1 years) were currently suffering from warts compared with 17 of 60 (28.3%) post-transplantation patients (34 male, median age 13.9 years). A further 14 pre-transplantation and 16 post-transplantation patients had previously suffered from warts which had resolved. Forty-one patients had sought treatment for warts, mainly from primary care. Five patients, all having received transplants, were seen by a dermatologist. Self-rated levels of pain and emotional upset were generally low, apart from those of four adolescent patients who expressed significant emotional upset. We concluded that cutaneous warts are more common among CKD patients. Appropriate information and treatment are required before and after transplantation. The majority of warts can be treated in primary care, but selected patients with extensive warts that cause distress need early referral for dermatology opinion.
authors.affiliation: Children's Renal and Urology Unit, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Andy
authors.initials: A
authors.lastname: Lunn
authors.forename: Jane
authors.initials: J
authors.lastname: Ravenscroft
authors.forename: Alan R
authors.initials: AR
authors.lastname: Watson
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007674:Kidney Diseases / Q000150:complications / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D027383:Papillomaviridae / Q000472:pathogenicity*; D030361:Papillomavirus Infections / Q000523:psychology / Q000628:therapy / Q000821:virology*; D018570:Risk Assessment; D012307:Risk Factors; D017193:Skin Diseases, Viral / Q000523:psychology / Q000628:therapy / Q000821:virology*; D013315:Stress, Psychological / Q000209:etiology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014860:Warts / Q000628:therapy / Q000821:virology*; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents