title: Measles in Papua New Guinea: an age-specific serological survey.
abstract: We aimed to determine the proportion of the population in Madang (Papua New Guinea) immune to measles infection by age groups, with respect to immunization status and study location, using dried blood sampling technology. We performed a prospective cross-sectional sero-survey. Population immunity against measles was sub-optimal (77%) and reported measles vaccine coverage in children <10 years of age was low (41%). The urban population was more susceptible to measles infection, compared with the rural population (66% vs 79% immune, aOR=0.6, p=0.05). Sero-conversion and long term protection rates appeared to be higher when at least one dose of vaccine was provided at or after 12 months of age (84% vs 59%, aOR=4.3, p=0.004). Such a dose is, however, not currently prescribed by the national immunization schedule.
authors.affiliation: Papua New Guinea Institute of Medical Research, PO Box 60, Goroka, Papua New Guinea. nicolas.senn@gmail.com
authors.forename: Nicolas
authors.initials: N
authors.lastname: Senn
authors.forename: Michaela
authors.initials: M
authors.lastname: Riddell
authors.forename: Matthew
authors.initials: M
authors.lastname: Omena
authors.forename: Peter
authors.initials: P
authors.lastname: Siba
authors.forename: John C
authors.initials: JC
authors.lastname: Reeder
authors.forename: C John
authors.initials: CJ
authors.lastname: Clements
authors.forename: Chris
authors.initials: C
authors.lastname: Morgan
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007115:Immunization Schedule; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology*; D008458:Measles Vaccine / Q000008:administration & dosage; D010219:Papua New Guinea / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D012424:Rural Population; D014505:Urban Population; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D008458:Measles Vaccine