title: Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.
abstract: Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.
authors.affiliation: Sibley School of Mechanical & Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Jason P
authors.initials: JP
authors.lastname: Gleghorn
authors.forename: Erica D
authors.initials: ED
authors.lastname: Pratt
authors.forename: Denise
authors.initials: D
authors.lastname: Denning
authors.forename: He
authors.initials: H
authors.lastname: Liu
authors.forename: Neil H
authors.initials: NH
authors.lastname: Bander
authors.forename: Scott T
authors.initials: ST
authors.lastname: Tagawa
authors.forename: David M
authors.initials: DM
authors.lastname: Nanus
authors.forename: Paraskevi A
authors.initials: PA
authors.lastname: Giannakakou
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Kirby
mesh_terms: D055910:Antibodies, Immobilized / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D045744:Cell Line, Tumor; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D008297:Male; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D008856:Microscopy, Fluorescence; D009360:Neoplastic Cells, Circulating / Q000276:immunology / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000276:immunology*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D055910:Antibodies, Immobilized; D000911:Antibodies, Monoclonal; D017430:Prostate-Specific Antigen