title: Carcinoma of the papilla of Vater following treatment of pancreaticobiliary maljunction.
abstract: Pancreaticobiliary maljunction (PBM) is frequently associated with biliary cancer due to reflux of pancreatic enzymes into the choledochus, and even after surgery to correct the PBM such patients still have a risk of residual bile duct cancer. Here, we report the case of a 59-year-old female with carcinoma of the papilla of Vater which developed 2.5 years after choledochoduodenostomy for PBM. During the postoperative follow-up period, computed tomography obtained 2 years after the first operation demonstrated a tumor in the distal end of the choledochus, although she did not have jaundice and laboratory tests showed no abnormalities caused by the previous operation. As a result, carcinoma of the papilla of Vater was diagnosed at an early stage, followed by surgical cure. For early detection of periampullary cancer in patients undergoing surgery for PBM, careful long-term follow-up is needed.
authors.affiliation: Department of Surgery, Teikyo University School of Medicine University Hospital, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki 213-8507, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Watanabe
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Midorikawa
authors.forename: Taketoshi
authors.initials: T
authors.lastname: Yamano
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Mushiake
authors.forename: Naoto
authors.initials: N
authors.lastname: Fukuda
authors.forename: Takashi
authors.initials: T
authors.lastname: Kirita
authors.forename: Kunio
authors.initials: K
authors.lastname: Mizuguchi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D014670:Ampulla of Vater / Q000473:pathology*; D017734:Bile Ducts, Extrahepatic / Q000002:abnormalities*; D003138:Common Bile Duct Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D010183:Pancreatic Ducts / Q000002:abnormalities*; D011183:Postoperative Complications / Q000209:etiology*