title: The role of transcranial Doppler embolic monitoring in the management of intracranial arterial stenosis.
abstract: Intracranial arterial stenosis (IAS) is thought to be responsible for 8% of all ischemic stroke subtypes. The best medical treatment for this condition is still controversial. Transcranial Doppler (TCD) emboli monitoring may help to guide the treatment by measuring the frequency of microembolic signals (MES). We report a case of IAS where TCD emboli monitoring proved useful in establishing the mechanism of stroke by being artery-to-artery emboli and guiding therapy based on the frequent symptoms and number of MES.
authors.affiliation: Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Joseph
authors.initials: J
authors.lastname: Sebastian
authors.forename: Carol
authors.initials: C
authors.lastname: Derksen
authors.forename: Khurshid
authors.initials: K
authors.lastname: Khan
authors.forename: Maher
authors.initials: M
authors.lastname: Saqqur
mesh_terms: D015901:Angiography, Digital Subtraction; D001241:Aspirin / Q000627:therapeutic use; D000069059:Atorvastatin; D001783:Blood Flow Velocity; D002533:Cerebral Angiography; D000077144:Clopidogrel; D003251:Constriction, Pathologic; D003937:Diagnosis, Differential; D005260:Female; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D020766:Intracranial Embolism / Q000175:diagnosis* / Q000188:drug therapy; D002546:Ischemic Attack, Transient / Q000175:diagnosis* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011758:Pyrroles / Q000627:therapeutic use; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D017585:Ultrasonography, Doppler, Transcranial; D055815:Young Adult
chemical_list: D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010975:Platelet Aggregation Inhibitors; D011758:Pyrroles; D000069059:Atorvastatin; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin