Diffuse liver infiltration by melanoma of unknown primary origin: one case report and literature review.
Diffuse liver infiltration by melanoma of unknown primary origin is rare. We encountered a unique case of diffuse liver infiltration by melanoma of unknown primary origin in our hospital. A 62-year-old woman was referred to our hospital for anorexia of 6 months duration and abdominal distension for 1 month. Ultrasonography (US), computerized tomography (CT) and magnetic resonance imaging (MRI) revealed an obvious enlarged liver without detectable nodules. She was diagnosed as liver metastasis by melanoma of unknown primary origin via percutaneous liver biopsy. The report demonstrates the difficulty of making a noninvasive diagnosis of diffuse hepatic infiltration on metastatic melanoma.
Shan
Guo-Dong
GD
Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xu
Guo-Qiang
GQ
Chen
Li-Hua
LH
Wang
Zhao-Ming
ZM
Jin
En-Yun
EY
Hu
Feng-Ling
FL
Li
You-Ming
YM
D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000556:secondary*; D008545:Melanoma / Q000473:pathology* / Q000556:secondary*; D008875:Middle Aged