Cytologic features and differential diagnosis in a case of extraskeletal mesenchymal chondrosarcoma: a case report.
BACKGROUND
Extraskeletal myxoid chondrosarcoma (EMC) is an uncommon tumor. On fine needle aspiration (FNA) it has to be distinguished from other benign and malignant soft tissue lesions.


METHODS
FNA was done on an 85-year-old man with painful swelling of the forearm. Smears showed fragments comprised of polygonal cells with eccentric nuclei and peripheral fine cytoplasmic vacuoles embedded in a dense, metachromatic matrix. Cell block showed similar cells in a chondromyxoid stroma. The cells were positive for S100 and negative for cytokeratin.


CONCLUSIONS
FNA is a useful tool in the diagnosis of EMC in conjunction with radiology. A preoperative diagnosis can be made due to its distinct cytologic and immunohistochemical features, obviating the need for a biopsy.
Handa
Uma
U
Department of Pathology, Government Medical College, Chandigarh, India.
Singhal
Niti
N
Punia
Rajpal Singh
RS
Garg
Sudhir
S
Mohan
Harsh
H
D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology; D018211:Chondrosarcoma, Mesenchymal / Q000175:diagnosis* / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male