Physiological versatility of the extremely thermoacidophilic archaeon Metallosphaera sedula supported by transcriptomic analysis of heterotrophic, autotrophic, and mixotrophic growth.
Comparative transcriptomic analysis of autotrophic, heterotrophic, and mixotrophic growth of the archaeon Metallosphaera sedula (70 degrees C, pH 2.0) revealed candidates for yet-to-be-confirmed components of the 3-hydroxypropionate/4-hydroxybutyrate pathway and implicated a membrane-bound hydrogenase (Msed_0944-Msed_0946) for growth on H(2). Routes for generation of ATP and reducing equivalents were also identified.
Auernik
Kathryne S
KS
Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, USA.
Kelly
Robert M
RM
D000332:Aerobiosis / Q000235:genetics; D019843:Archaeal Proteins / Q000235:genetics / Q000378:metabolism; D052818:Autotrophic Processes; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D020869:Gene Expression Profiling; D019848:Gene Expression Regulation, Archaeal; D052836:Heterotrophic Processes; D006358:Hot Temperature; D006885:Hydroxybutyrates / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D013379:Substrate Specificity / Q000235:genetics; D016943:Sulfolobaceae / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D013696:Temperature
D019843:Archaeal Proteins; D002247:Carbon Isotopes; D006885:Hydroxybutyrates; D002245:Carbon Dioxide