title: Linear scleroderma "en coup de sabre": initial presentation as intractable partial seizures in a child.
abstract: Linear scleroderma is a form of localized scleroderma characterized by sclerotic lesions distributed in a linear, band-like pattern. The "en coup de sabre" subtype of linear scleroderma is more often associated with systemic morbidity, including ocular, oral, and neurological abnormalities. Here, we report one patient with typical linear scleroderma "en coup de sabre" (LSCS). Initially, he presented with refractory partial seizures before the characteristic skins lesion on his head developed. This was a rare case with obvious brain parenchyma involvement. We did not prescribe medication but performed serial brain magnetic resonance imaging follow-up for the intraparenchymal lesion. The atrophic changes of the skin, face and brain remained the same, and his seizures had not worsened at the most recent follow-up. Parry-Romberg syndrome, a very similar condition, should be differentiated from LSCS.
authors.affiliation: Department of Pediatrics, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Kuo-Liang
authors.initials: KL
authors.lastname: Chiang
authors.forename: Kai-Ping
authors.initials: KP
authors.lastname: Chang
authors.forename: Tai-Tong
authors.initials: TT
authors.lastname: Wong
authors.forename: Ting-Rong
authors.initials: TR
authors.lastname: Hsu
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004828:Epilepsies, Partial / Q000209:etiology*; D005150:Facial Hemiatrophy / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D012594:Scleroderma, Localized / Q000150:complications / Q000175:diagnosis*