[Chlamydial infection in asthma. Macrolide treatment].
Atypical microorganism infections, including Chlamydophila pneumoniae, play an important role in asthma course. A significant influence of chlamydial infection on severity of asthma exacerbations and increase in chronic asthma symptoms has been shown. The group of medication with high antibacterial activity against atypical microorganisms are macrolides, which also have anti-inflammatory and immunomodulatory effects. Macrolide treatment in patients with asthma can be connected with additional therapeutic benefits. Mechanism of action of these antibiotics is not ultimately clarified and further studies are required.
Kosińska
Magdalena
M
Katedra i Klinika Chorób Wewnetrznych, Geriatrii i Alergologii we Wrocławiu. wroblaha@yahoo.com
Kraus-Filarska
Maria
M
D001249:Asthma / Q000188:drug therapy* / Q000382:microbiology*; D002648:Child; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification; D006801:Humans; D018942:Macrolides / Q000627:therapeutic use*
D018942:Macrolides