title: Clopidogrel-associated acute arthritis.
abstract: A 54-year-old Japanese man was urgently admitted to our hospital because of "unmovable" polyarthralgia, high fever and pruritus. He had taken clopidogrel 3 weeks before this admission to prevent ischemic cerebrovascular events. On the laboratory values, acute phase reactants and serum IgE were elevated. Although his symptoms had promptly improved with non-steroidal anti-inflammatory drugs (NSAIDs) and cessation of the drug, the same phenomena were re-induced by re-administration of the drug. According to the above manifestations, he was diagnosed as suffering from clopidogrel-associated acute arthritis.
authors.affiliation: Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. shinya22@nagasaki-u.ac.jp
authors.forename: Shin-ya
authors.initials: SY
authors.lastname: Kawashiri
authors.forename: Masatake
authors.initials: M
authors.lastname: Taguchi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawakami
authors.forename: Katsumi
authors.initials: K
authors.lastname: Eguchi
mesh_terms: D000208:Acute Disease; D018771:Arthralgia / Q000139:chemically induced / Q000175:diagnosis; D001168:Arthritis / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D002062:Bursitis / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D000077144:Clopidogrel; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D012785:Shoulder Joint / Q000473:pathology; D013988:Ticlopidine / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine