Anti-microbial peptides for plaque control and beyond.
Anti-microbial peptides perform many functions in the oral cavity. They may provide protection against microbial pathogens, assist in oral biofilm control, and function as an important part of the innate immune system in response to local and systemic infection. Synthetic versions of these peptides may be useful to supplement natural anti-microbial peptides or as therapeutic agents.
Gilmore
Katherine
K
Microbiology Branch, U.S. Army Dental and Trauma Research Detachment, Walter Reed Army Institute of Research, Great Lakes, Ill 60088, USA.
Chen
Ping
P
Leung
Kai P
KP
D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000008:administration & dosage / Q000737:chemistry / Q000502:physiology / Q000627:therapeutic use; D001421:Bacteria, Anaerobic / Q000187:drug effects; D018441:Biofilms / Q000187:drug effects; D002180:Candidiasis, Oral / Q000188:drug therapy; D003773:Dental Plaque / Q000188:drug therapy*; D006564:Herpesviridae / Q000187:drug effects; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D052016:Mucositis / Q000188:drug therapy; D013280:Stomatitis / Q000188:drug therapy; D015854:Up-Regulation
D023181:Antimicrobial Cationic Peptides