title: Spontaneous liver rupture in hypereosinophilic syndrome: a rare but fatal complication.
abstract: We report a rare case of spontaneous liver rupture in a patient with hypereosinophilic syndrome (HES), of which the diagnosis was delayed, resulting in a fatal outcome. The diagnostic criteria and treatment of HES with hepatic involvement were reviewed. The possible cause of spontaneous liver rupture in HES and its management were also discussed. To our knowledge, this is the first case report of spontaneous liver rupture in HES. We emphasized the need of a high index of suspicion in diagnosing HES, so that early treatment could be initiated.
authors.affiliation: Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Yue-Sun
authors.initials: YS
authors.lastname: Cheung
authors.forename: Shun
authors.initials: S
authors.lastname: Wong
authors.forename: Philip Koon-Ngai
authors.initials: PK
authors.lastname: Lam
authors.forename: Kit-Fai
authors.initials: KF
authors.lastname: Lee
authors.forename: John
authors.initials: J
authors.lastname: Wong
authors.forename: Paul Bo-San
authors.initials: PB
authors.lastname: Lai
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous / Q000175:diagnosis / Q000209:etiology / Q000401:mortality