title: Obstructive lung disease from conception to old age: differences in the treatment of adults and children with asthma.
abstract: Achieving asthma control is the focus of asthma management. Inhaled corticosteroids are the most effective treatment for asthma in children and adults, with no evidence that the magnitude of benefit differs between adults and school-aged children. Leukotriene inhibitors are more widely used in children than in adults. This may be because provoking stimuli, such as environmental allergens and frequent exercise, are more important asthma triggers in children or because parental concerns about the side effects of treatment with ICS. Inhaled corticosteroid/long-acting inhaled beta(2)-agonist combinations may not be as effective in children as in they are adults in improving asthma control and reducing asthma exacerbations.
authors.affiliation: Firestone Institute for Respiratory Health, St. Joseph's Hospital and Department of Medicine, McMaster University, Hamilton, Ontario, Canada. obyrnep@mcmaster.ca
authors.forename: Paul M
authors.initials: PM
authors.lastname: O'Byrne
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D006801:Humans; D015289:Leukotrienes
chemical_list: D000305:Adrenal Cortex Hormones; D000319:Adrenergic beta-Antagonists; D015289:Leukotrienes