Long-term results of vaginal repairs with and without xenograft reinforcement.
OBJECTIVE
The aim of this paper is to study if xenograft reinforcement of vaginal repair reduces recurrence of prolapse.


METHODS
Results 1-5 years after vaginal repair were studied in 41 cases with xenograft and in 82 matched controls without. Symptoms were evaluated by a validated questionnaire and anatomy by pelvic organ prolapse quantification (POPQ).


RESULTS
Significant more cases, 97% versus 81% controls, felt cured or much improved (p = 0.02); 11% of cases and 19% of controls had POP symptoms, POPQ > -1 was found in 31% cases and 24% controls. Defining recurrence as POPQ > -1 plus symptoms revealed recurrence in 3% of cases and 12% controls. None of the recurrence rates was significantly different for cases versus controls. No vaginal erosions were seen. Previous surgery was a significant risk factor with odds ratio 7.3 for another recurrence.


CONCLUSIONS
Recurrence rates defined by POPQ plus symptoms were low compared to literature. Xenograft reinforcement might improve results.
Mouritsen
Lone
L
Department of Gynecology and Obstetrics, Herlev Hospital, University of Copenhagen, 2730 Herlev, Copenhagen, Denmark. lonemouritsen@newmail.dk
Kronschnabl
Manuela
M
Lose
Gunnar
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001684:Biological Dressings; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D014621:Vagina / Q000601:surgery*