Near-infrared spectroscopy as an index of brain and tissue oxygenation.
Continuous real-time monitoring of the adequacy of cerebral perfusion can provide important therapeutic information in a variety of clinical settings. The current clinical availability of several non-invasive near-infrared spectroscopy (NIRS)-based cerebral oximetry devices represents a potentially important development for the detection of cerebral ischaemia. In addition, a number of preliminary studies have reported on the application of cerebral oximetry sensors to other tissue beds including splanchnic, renal, and spinal cord. This review provides a synopsis of the mode of operation, current limitations and confounders, clinical applications, and potential future uses of such NIRS devices.
Murkin
J M
JM
Department of Anesthesiology and Perioperative Medicine, University Hospital-LHSC, University of Western Ontario, Rm C3-112, 339 Windermere Rd, London, ON, Canada N6A 5A5. john.murkin@lhsc.on.ca
Arango
M
M
D002545:Brain Ischemia / Q000175:diagnosis*; D006348:Cardiac Surgical Procedures; D002648:Child; D015986:Confounding Factors, Epidemiologic; D016894:Endarterectomy, Carotid; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*; D010092:Oximetry / Q000379:methods; D010101:Oxygen Consumption / Q000502:physiology*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*