Chiral bifunctional phase transfer catalysts for asymmetric fluorination of beta-keto esters.
Chiral bifunctional phase transfer catalysts introducing bis(diarylhydroxymethyl) substituents at 3,3'-positions of the chiral binaphthyl core were successfully applied to asymmetric fluorination of cyclic beta-keto esters with high enantioselectivities.
Wang
Xisheng
X
Laboratory of Synthetic Organic Chemistry, Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.
Lan
Quan
Q
Shirakawa
Seiji
S
Maruoka
Keiji
K
D002384:Catalysis; D018360:Crystallography, X-Ray; D004952:Esters; D054879:Halogenation; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry*; D044367:Phase Transition; D013237:Stereoisomerism
D004952:Esters; D009281:Naphthalenes; C031721:naphthalene