title: Enantioselective Ag-Catalyzed Allylation of Aldimines.
abstract: A highly enantioselective synthesis of homoallylic amines, using allyltrimethoxysilane under Ag(I) catalytic conditions, has been developed. Among the chiral ligands investigated, a remarkable difference in the resulting Ag(I) complexes was observed. Under mild conditions and low catalyst loadings, homoallylamines were produced in high ee values (up to 80%) and good yields. The methodology can be further extended to a diastere- and enantioselective crotylation of aldimines.
authors.affiliation: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
authors.forename: Marina
authors.initials: M
authors.lastname: Naodovic
authors.forename: Manabu
authors.initials: M
authors.lastname: Wadamoto
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamamoto