Catalytic asymmetric conjugate addition of dialkylzinc reagents to alpha,beta-unsaturated sulfones.
An efficient method is reported for the highly enantioselective copper-catalyzed conjugate addition of dialkylzinc reagents to alpha,beta-unsaturated sulfones using a monodentate phosphoramidite ligand.
Bos
Pieter H
PH
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Maciá
Beatriz
B
Fernández-Ibáñez
M Angeles
MA
Minnaard
Adriaan J
AJ
Feringa
Ben L
BL