Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.
OBJECTIVE
To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP).


METHODS
We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery, type of surgery, duodenal polyps and colorectal cancer at surgery were analyzed.


RESULTS
During WCE, polyps were detected in 9/14 (64.3%) patients. Duodenal adenomatous polyps were found in nine (64.3%) patients, and jejunal and ileal polyps in seven (50%) and eight (57.1%), respectively. The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps. Identification of the ampulla of Vater was not achieved with WCE. Importantly, the findings of WCE had no immediate impact on the further clinical management of FAP patients. No procedure-related complications were observed in the patients.


CONCLUSIONS
WCE is a promising noninvasive new method for the detection of small-intestinal polyps. Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.
Katsinelos
Panagiotis
P
Department of Endoscopy and Motility Unit, Central Hospital, Ethnikis Aminis 41, 54635, Thessaloniki, Greece.
Kountouras
Jannis
J
Chatzimavroudis
Grigoris
G
Zavos
Christos
C
Pilpilidis
Ioannis
I
Fasoulas
Kostas
K
Paroutoglou
George
G
D011125:Adenomatous Polyposis Coli / Q000473:pathology*; D000328:Adult; D053704:Capsule Endoscopy; D005260:Female; D006115:Greece; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis* / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult