title: Synthesis and characterization of stigmasterol oxidation products.
abstract: The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects. Biological evaluation of the oxides of phytosterols is significant in the context of increased dietary use of phytosterols in the drive to reduce cholesterol absorption.
authors.affiliation: Department of Chemistry and School of Pharmacy, Analytical and Biological Chemistry Research Facility, University College Cork, Cork, Ireland.
authors.forename: David A
authors.initials: DA
authors.lastname: Foley
authors.forename: Yvonne
authors.initials: Y
authors.lastname: O'Callaghan
authors.forename: Nora M
authors.initials: NM
authors.lastname: O'Brien
authors.forename: Florence O
authors.initials: FO
authors.lastname: McCarthy
authors.forename: Anita R
authors.initials: AR
authors.lastname: Maguire
mesh_terms: D010084:Oxidation-Reduction; D013265:Stigmasterol / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D013265:Stigmasterol