title: Reactive lesions of peri-implant mucosa associated with titanium dental implants: a report of 2 cases.
abstract: The aim of this study was to report 2 novel clinical cases of reactive lesions of the peri-implant mucosa associated with titanium dental implants where metal-like particles were observed histologically. In both cases, the lesions were diagnosed as epulis, based on clinical evidence. Extirpation biopsies were carried out. Case 1 was diagnosed as pyogenic granuloma and case 2 as peripheral giant cell granuloma. The presence of metal-like particles in the tissues suggests that the etiology of the lesions might be related to the corrosion process of the metal structure. This is the first case of pyogenic granuloma to be reported in association with dental implants. All clinical cases of soft tissue lesions associated with implants should be reported to contribute to the understanding of the etiology and pathogeny of these lesions.
authors.affiliation: Department of Oral Pathology, School of Dentistry, University of Buenos Aires, Buenos Aires, Argentina. dolmedo@argentina.com
authors.forename: D G
authors.initials: DG
authors.lastname: Olmedo
authors.forename: M L
authors.initials: ML
authors.lastname: Paparella
authors.forename: D
authors.initials: D
authors.lastname: Brandizzi
authors.forename: R L
authors.initials: RL
authors.lastname: Cabrini
mesh_terms: D000368:Aged; D003343:Corrosion; D015921:Dental Implants / Q000009:adverse effects*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006101:Granuloma, Giant Cell / Q000209:etiology / Q000473:pathology / Q000601:surgery; D017789:Granuloma, Pyogenic / Q000209:etiology / Q000473:pathology / Q000601:surgery; D006801:Humans; D008439:Maxillary Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D014025:Titanium / Q000009:adverse effects
chemical_list: D015921:Dental Implants; D014025:Titanium