Influence of patient age on the association between euploidy and day-3 embryo morphology.
A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced by maternal age.
Eaton
Jennifer L
JL
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Hacker
Michele R
MR
Barrett
C Brent
CB
Thornton
Kim L
KL
Penzias
Alan S
AS
D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D010064:Embryo Implantation / Q000502:physiology; D004624:Embryo Transfer / Q000379:methods; D047108:Embryonic Development / Q000502:physiology; D005260:Female; D006801:Humans; D008423:Maternal Age; D011003:Ploidies; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000379:methods; D012189:Retrospective Studies