title: Synthesis of 3-hydroxyoxindoles by Pd-catalysed intramolecular nucleophilic addition of aryl halides to alpha-ketoamides.
abstract: Pd/PtBu(3)-catalysed intramolecular nucleophilic addition of aryl halides to alpha-ketoamides in the presence of nBuOH and base has been realized with high yields, providing a new, direct, and efficient synthetic strategy to obtain 3-hydroxyoxindoles.
authors.affiliation: Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland.
authors.forename: Yi-Xia
authors.initials: YX
authors.lastname: Jia
authors.forename: Dmitry
authors.initials: D
authors.lastname: Katayev
authors.forename: E Peter
authors.initials: EP
authors.lastname: Kündig