Needle preference in patients receiving cosmetic botulinum toxin type A.
BACKGROUND
Patients often complain of pain and bruising from needle injections. Some clinicians believe smaller gauge needles cause less pain. Thirty-gauge needles are currently the standard needles employed for administering botulinum toxin type A (BTX-A).


OBJECTIVE
This study sought to determine whether patients receiving BTX-A have a preference for 30-gauge or 32-gauge needles based on the amount of pain and bruising experienced.


METHODS
Thirty-seven subjects received BTX-A on the right side of the face using a 30-gauge needle and on the left side using a 32-gauge needle. Subjects were masked to needle size. They were then asked to rate injection pain on an 11-point numerical rating scale and to note any bruising. Physician preference was also evaluated.


RESULTS
There were no statistically significant differences in the amount of intra-procedural pain (p=.37) or the level of post-procedural pain and discomfort (p=.76) experienced. Twenty-seven percent of subjects reported greater bruising with the 32-gauge needle, versus 29.7% with the 30-gauge needle. The physician injector did not have a preference. Lastly, 83.8% of subjects did not detect a difference in BTX-A paralysis effect.


CONCLUSIONS
We do not recommend using 32-gauge needles in place of 30-gauge needles for administering BTX-A.
Price
Kristina M
KM
Department of Orbital, Oculoplastic and Reconstructive Surgery, Duke Eye Center, Durham, North Carolina, USA. kpricemd@bowdeneye.com
Williams
Zinaria Y
ZY
Woodward
Julie A
JA
D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D009339:Needles / Q000009:adverse effects*; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D010147:Pain Measurement; D010342:Patient Acceptance of Health Care; D017060:Patient Satisfaction; D016037:Single-Blind Method
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A