title: Is there a role for anything other than a Nissen's operation?
abstract: BACKGROUND
  The Nissen fundoplication is the most frequently applied antireflux operation worldwide. The aim of this review was to compare laparoscopic Nissen with partial fundoplication.
  
  
  METHODS
  Nine randomized trials comparing several types of wraps were analyzed, four for the comparison Nissen vs. Toupet and five for the comparison Toupet or Nissen vs. anterior fundoplication. Similar comparisons in nonrandomized studies were also included.
  
  
  RESULTS
  Dysphagia rates and reflux recurrence were not related to preoperative esophageal persistalsis independent of the selected procedure. Overall, Nissen fundoplication revealed slightly better reflux control, but was associated with more side effects, such as early dysphagia and gas bloat. Advantages of an anterior approach were only reported by one group. A significantly higher reflux recurrence rate for anterior fundoplication was observed in all other comparisons.
  
  
  CONCLUSIONS
  Tailoring antireflux surgery according to esophageal motility is not indicated. At present, the relevant factor for selection of a Nissen or Toupet fundoplication is personal experience. Anterior fundoplication offers less effective long-term reflux control.
authors.affiliation: Chirurgische Klinik und Poliklinik I, Klinikum der Universität Würzburg, Würzburg, Germany. fein@chirurgie.uni-wuerzburg.de
authors.forename: Martin
authors.initials: M
authors.lastname: Fein
authors.forename: Florian
authors.initials: F
authors.lastname: Seyfried
mesh_terms: D002986:Clinical Trials as Topic; D018662:Fundoplication / Q000009:adverse effects / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans