Diabetic ketoacidosis, thyroiditis and alopecia areata in a child with Down syndrome.
A 10-year-old girl with Down syndrome and alopecia areata was admitted with severe ketoacidosis. She had high blood glucose level: 615 mg/dL and her HbAlc level was 13.3 %. After the control of ketoacidosis and reduction of the plasma glucose level, we found low free T4 level and high TSH levels. Thyroid peroxidase antibodies titer was 1383 IU/mL and both gliadin and endomysial antibodies were negative. This was the first report of a child with Down syndrome showing type 1 diabetes combined with alopecia areata and autoimmune thyroid disease.
Pirgon
Ozgur
O
Department of Pediatric Endocrinology, Konya Research and Training Hospital, Turkey. ozpirgon@hotmail.com
Atabek
Mehmet Emre
ME
Sert
Ahmet
A
D000506:Alopecia Areata; D002648:Child; D016883:Diabetic Ketoacidosis; D004314:Down Syndrome; D005260:Female; D050031:Hashimoto Disease; D006801:Humans