Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience.
Peptides are particularly attractive as molecular building blocks in the bottom-up fabrication of supramolecular structures based on self-assembly and have potential in many important applications in the fields of biotechnology and bioengineering. In the first part of this critical review the main categories of peptide-based amphiphiles will be discussed by showing some relevant examples, which demonstrate the importance of amphiphilic peptides as molecular building blocks for nanostructures. In the second part of this review we will review the cross-disciplinary role of peptide-based supramolecular nanoarchitectures ranging from chemistry to biology, medicine, materials science, and engineering through discussing several examples of applied nanomaterials (216 references).
Cavalli
Silvia
S
CIBER-BBN, Networking Centre on Bioengineering, Biomaterials, and Nanomedicine, Barcelona Science Park, 08028 Barcelona, Spain. silvia.cavalli@irbbarcelona.org
Albericio
Fernando
F
Kros
Alexander
A
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008969:Molecular Sequence Data; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D015202:Protein Engineering
D010455:Peptides