title: Coexisting vasospastic angina and undiagnosed Brugada syndrome resulting in cardiac arrest.
abstract: The coexistence of Brugada Syndrome and resting vasospastic angina resulting in cardiac arrest is rare. We describe a 64 year-old man presenting with cardiac arrest and vasospastic angina with diagnostic criteria of symptomatic Brugada Syndrome. Recognition of the coexistence of these potentially fatal conditions has important therapeutic implications when using calcium channel antagonists and may shed light on the mechanisms of coronary spasm. A common pathogenesis, such as a common underlying channelopathy, may explain its coexistence with Brugada Syndrome.
authors.forename: Vincent
authors.initials: V
authors.lastname: Chow
authors.forename: Isuru
authors.initials: I
authors.lastname: Ranasinghe
authors.forename: John
authors.initials: J
authors.lastname: Yiannikas
mesh_terms: D000789:Angina, Unstable / Q000150:complications / Q000175:diagnosis*; D053840:Brugada Syndrome / Q000150:complications / Q000175:diagnosis*; D003329:Coronary Vasospasm / Q000150:complications / Q000175:diagnosis*; D006323:Heart Arrest / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged