Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.
Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.
Gleghorn
Jason P
JP
Sibley School of Mechanical & Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Pratt
Erica D
ED
Denning
Denise
D
Liu
He
H
Bander
Neil H
NH
Tagawa
Scott T
ST
Nanus
David M
DM
Giannakakou
Paraskevi A
PA
Kirby
Brian J
BJ
D055910:Antibodies, Immobilized / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D045744:Cell Line, Tumor; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D008297:Male; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D008856:Microscopy, Fluorescence; D009360:Neoplastic Cells, Circulating / Q000276:immunology / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000276:immunology*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D055910:Antibodies, Immobilized; D000911:Antibodies, Monoclonal; D017430:Prostate-Specific Antigen