title: Cardiovascular magnetic resonance in carotid atherosclerotic disease.
abstract: Atherosclerosis is a chronic, progressive, inflammatory disease affecting many vascular beds. Disease progression leads to acute cardiovascular events such as myocardial infarction, stroke and death. The diseased carotid alone is responsible for one third of the 700,000 new or recurrent strokes occurring yearly in the United States. Imaging plays an important role in the management of atherosclerosis, and cardiovascular magnetic resonance (CMR) of the carotid vessel wall is one promising modality in the evaluation of patients with carotid atherosclerotic disease. Advances in carotid vessel wall CMR allow comprehensive assessment of morphology inside the wall, contributing substantial disease-specific information beyond luminal stenosis. Although carotid vessel wall CMR has not been widely used to screen for carotid atherosclerotic disease, many trials support its potential for this indication. This review summarizes the current state of knowledge regarding carotid vessel wall CMR and its potential clinical application for management of carotid atherosclerotic disease.
authors.affiliation: Department of Radiology, University of Washington, Seattle, WA, USA. lido2@u.washington.edu
authors.forename: Li
authors.initials: L
authors.lastname: Dong
authors.forename: William S
authors.initials: WS
authors.lastname: Kerwin
authors.forename: Marina S
authors.initials: MS
authors.lastname: Ferguson
authors.forename: Rui
authors.initials: R
authors.lastname: Li
authors.forename: Jinnan
authors.initials: J
authors.lastname: Wang
authors.forename: Huijun
authors.initials: H
authors.lastname: Chen
authors.forename: Gador
authors.initials: G
authors.lastname: Canton
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Hatsukami
authors.forename: Chun
authors.initials: C
authors.lastname: Yuan
mesh_terms: D002114:Calcinosis / Q000473:pathology; D002318:Cardiovascular Diseases / Q000209:etiology / Q000473:pathology; D002339:Carotid Arteries / Q000737:chemistry / Q000473:pathology*; D016893:Carotid Stenosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005355:Fibrosis; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007249:Inflammation / Q000473:pathology; D008055:Lipids / Q000032:analysis; D008279:Magnetic Resonance Imaging; D009336:Necrosis; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012720:Severity of Illness Index
chemical_list: D008055:Lipids