Iodized oil uptake assessment with cone-beam CT in chemoembolization of small hepatocellular carcinomas.
OBJECTIVE
To evaluate the utility of assessing iodized oil uptake with cone-beam computed tomography (CT) in transarterial chemoembolization (TACE) for small hepatocellular carcinoma (HCC).


METHODS
Cone-beam CT provided by a biplane flat-panel detector angiography suite was performed on eighteen patients (sixteen men and two women; 41-76 years; mean age, 58.9 years) directly after TACE for small HCC (26 nodules under 30 mm; mean diameter, 11.9 mm; range, 5-28 mm). The pre-procedural locations of the tumors were evaluated using triphasic multi-detector row helical computed tomography (MDCT). The tumor locations on MDCT and the iodized oil uptake by the tumors were analyzed on cone-beam CT and on spot image directly after the procedures.


RESULTS
All lesions on preprocedural MDCT were detected using iodized oil uptake in the lesions on cone-beam CT (sensitivity 100%, 26/26). Spot image depicted iodized oil uptake in 22 of the lesions (sensitivity 85%). The degree of iodized oil uptake was overestimated (9%, 2/22) or underestimated (14%, 3/22) on spot image in five nodules compared with that of cone-beam CT.


CONCLUSIONS
Cone-beam CT is a useful and convenient tool for assessing the iodized oil uptake of small hepatic tumors (< 3 cm) directly after TACE.
Jeon
Ung Bae
UB
Department of Radiology, Pusan National University Hospital, Yangsan, South Korea.
Lee
Jun Woo
JW
Choo
Ki Seok
KS
Kim
Chang Won
CW
Kim
Suk
S
Lee
Tae Hong
TH
Jeong
Yeon Joo
YJ
Kang
Dae Hwan
DH
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000628:therapy; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D003287:Contrast Media / Q000378:metabolism*; D005260:Female; D006801:Humans; D007459:Iodized Oil / Q000378:metabolism*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D008875:Middle Aged
D003287:Contrast Media; D007459:Iodized Oil