High-photoluminescence-yield gold nanocubes: for cell imaging and photothermal therapy.
Gold nanocubes demonstrate unique optical properties of the high photoluminescence (PL) quantum yield and a remarkably enhanced extinction band at 544 nm. The 4 x 10(-2) PL yield, which is about 200 times higher than that of gold nanorods, allows gold nanocubes to be successfully used in cell imaging of human liver cancer cells (QGY) and human embryo kidney cells (293T) with a common method of single-photon excitation. The high extinction coefficients of gold nanocubes also facilitate them carrying out the photothermal therapy of QGY and 293T cells, showing similar photokilling efficiency as compared to gold nanorods.
Wu
Xi
X
Surface Physics Laboratory (National Key Laboratory), Department of Physics, Fudan University, Shanghai 200433, China.
Ming
Tian
T
Wang
Xin
X
Wang
Peinan
P
Wang
Jianfang
J
Chen
Jiyao
J
D045744:Cell Line, Tumor; D002470:Cell Survival / Q000528:radiation effects; D006046:Gold / Q000737:chemistry* / Q000378:metabolism*; D006358:Hot Temperature; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008163:Luminescent Measurements; D053768:Metal Nanoparticles / Q000737:chemistry*; D057054:Molecular Imaging / Q000379:methods*
D006046:Gold