Comparative activity of pradofloxacin, enrofloxacin, and azithromycin against Bartonella henselae isolates collected from cats and a human.
Using Bartonella henselae isolates from cats and a human, the activity of pradofloxacin was compared with those of enrofloxacin and azithromycin. By Etest and disc diffusion assay, pradofloxacin showed greater antimicrobial activity than did other antibiotics. We conclude that pradofloxacin may prove useful for the treatment of B. henselae infections.
Biswas
Silpak
S
Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA.
Maggi
Ricardo G
RG
Papich
Mark G
MG
Keil
Daniel
D
Breitschwerdt
Edward B
EB
D016917:Angiomatosis, Bacillary / Q000382:microbiology* / Q000662:veterinary*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017963:Azithromycin / Q000494:pharmacology; D018416:Bartonella henselae / Q000187:drug effects* / Q000302:isolation & purification; D002371:Cat Diseases / Q000382:microbiology*; D002372:Cat-Scratch Disease / Q000382:microbiology*; D002415:Cats; D000077422:Enrofloxacin; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077422:Enrofloxacin; C507250:pradofloxacin; D017963:Azithromycin