title: Cutaneous collagenous vasculopathy: ultrastructural and immunohistochemical study of a new case.
abstract: Cutaneous collagenous vasculopathy is a very rare entity first described in 2000, manifesting clinically with acquired, progressively diffuse, cutaneous telangiectases with a histologically distinct aspect, characterized by a thick hyaline collagenous wall. Its cause is unknown. Differential diagnosis includes mainly generalized essential telangiectasia and telangiectatic mastocytosis. We report a 65-year-old Caucasian patient who presented with progressive telangiectasia starting over the lower limbs that spread progressively upwards. Histopathologic (light and electron microscopic) examinations were typical of cutaneous collagenous vasculopathy. We review the salient clinicopathologic features of this poorly known condition.
authors.affiliation: Department of Dermatology, Ed. Herriot Hospital, Lyon, France. jean.kanitakis@univ-lyon1.fr
authors.forename: Jean
authors.initials: J
authors.lastname: Kanitakis
authors.forename: Monique
authors.initials: M
authors.lastname: Faisant
authors.forename: Daniel
authors.initials: D
authors.lastname: Wagschal
authors.forename: Marek
authors.initials: M
authors.lastname: Haftek
authors.forename: Alain
authors.initials: A
authors.lastname: Claudy
mesh_terms: D034861:Abdominal Wall / Q000473:pathology; D000368:Aged; D001415:Back / Q000473:pathology; D004550:Elbow / Q000473:pathology; D005542:Forearm / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007866:Leg / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D017445:Skin Diseases, Vascular / Q000473:pathology*; D013684:Telangiectasis / Q000473:pathology*