The comparison of methods for determination of humoral and cell-mediated immunity in patients with breast cancer.
We observed the immunological answer to antigens obtained from the human malignant breast tumor and from the blood of inbred mice strain C3H/H2K infected by LDH virus. We compared the modified ELISA method for humoral immunity with the leukocyte adherence inhibition (LAI) assay for cell-mediated immunity. The modified ELISA method is suitable for early diagnosing and monitoring antibodies in a malignant breast tumor simultaneously with senological examinations which include mammography and clinical examinations, because the antibodies are determined in a high number of samples by single application.
Nedbalová
M
M
Institute of Physiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic. martina.nedbalova@lf1.cuni.cz
Trojan
S
S
Dohnalová
A
A
Jandová
A
A
D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D001943:Breast Neoplasms / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D056724:Immunity, Humoral / Q000276:immunology*; D007957:Leukocyte Adherence Inhibition Test; D051379:Mice; D008809:Mice, Inbred C3H; D014777:Virus Diseases / Q000276:immunology
D000951:Antigens, Neoplasm; D000956:Antigens, Viral