Novel asymmetrically functionalized bis-dipicolylamine metal complexes: peripheral decoration of a potent anion recognition scaffold.
We report the design and synthesis of a novel class of asymmetrically functionalized, ditopic bis-dipicolylamine (BDPA) ligands. A key feature of this research involved the controlled, sequential functional group decoration of a potent molecular recognition scaffold. Calorimetric screening identified a BDPA analogue as a highly potent (K(a) approximately 10(6) M(-1)) and selective sensor for inorganic phosphate.
Drewry
Joel A
JA
Department of Chemistry, University of Toronto, 3359 Mississauga Road North, Mississauga, ON, CanadaL5L 1C6.
Fletcher
Steven
S
Hassan
Haider
H
Gunning
Patrick T
PT
D000588:Amines; D000838:Anions; D002151:Calorimetry; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry*; D010710:Phosphates / Q000032:analysis*; D010848:Picolinic Acids
C501847:2,2'-dipicolylamine; D000588:Amines; D000838:Anions; D008024:Ligands; D009942:Organometallic Compounds; D010710:Phosphates; D010848:Picolinic Acids