title: Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex.
abstract: A homogeneous assay is reported using Ru(phen)(2)(dppz)(2+) and a K(+)-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K(+).
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Min Sun
authors.initials: MS
authors.lastname: Choi
authors.forename: Minji
authors.initials: M
authors.lastname: Yoon
authors.forename: Jin-Ook
authors.initials: JO
authors.lastname: Baeg
authors.forename: Jinheung
authors.initials: J
authors.lastname: Kim
mesh_terms: D052157:Aptamers, Nucleotide / Q000032:analysis* / Q000737:chemistry; D002412:Cations / Q000737:chemistry; D054856:G-Quadruplexes; D011188:Potassium / Q000737:chemistry*; D017422:Sequence Analysis, DNA / Q000379:methods*; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D052157:Aptamers, Nucleotide; D002412:Cations; D011188:Potassium