B lymphocyte stimulator -817C>T promoter polymorphism and the predisposition for the development of deep infiltrating endometriosis.
The prevalence of the BLyS -817C>T polymorphic variant among women with either deep infiltrating endometriosis or adenomyosis compared with a group of gynecologic patients without symptomatic endometriosis and a group of healthy women was assessed in this study. Patients with deep infiltrating endometriosis had less often a BLyS -817C/T genotype as compared with the reference group, with an odds ratio of 0.50 (95% confidence interval 0.27-0.93 versus the C/C genotype).
de Graaff
Aisha A
AA
Department of Obstetrics and Gynecology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands. aa.de.graaff@mumc.nl
Dunselman
Gerard A J
GA
Delvoux
Bert
B
van Kaam
Kim J
KJ
Smits
Luc J M
LJ
Romano
Andrea
A
D000328:Adult; D053264:B-Cell Activating Factor / Q000235:genetics*; D016022:Case-Control Studies; D004715:Endometriosis / Q000235:genetics* / Q000473:pathology; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D010532:Peritoneal Diseases / Q000235:genetics* / Q000473:pathology; D020641:Polymorphism, Single Nucleotide / Q000502:physiology; D011401:Promoter Regions, Genetic / Q000235:genetics; D055815:Young Adult
D053264:B-Cell Activating Factor