[Stability of the tetramine in blood samples under different temperatures].
OBJECTIVE
To study the stability of tetramine in blood samples under different environment temperatures.


METHODS
The tetramine samples in 0.5 microg/mL concentration were stored in the environment temperature at 45 degrees C, 25 degrees C and 4 degrees C. The tetramine concentration were measured by GC-MS in 1, 3, 12, 18 and 39 days, respectively. And then the results of measurement were analyzed by SPSS software.


RESULTS
At 45 degrees C and 25 degrees C, the concentration of tetramine changed without distinctly in first 3 days and declined significantly from 4 days to 12 days. Thereafter it declined more slowly. At 4 degrees C, the concentration of tetramine changed without distinctly in 12 days and declined significantly from 13 days to 18 days. Thereafter it declined more slowly.


CONCLUSIONS
The concentration of tetra mine in blood samples is stable in 3 days. Thereafter it declined gradually. Temperature also influences the concentration of tetra mine.
Bu
Jun
J
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai, China.
Liu
Wei
W
Yan
Hui
H
D000704:Analysis of Variance; D000818:Animals; D001793:Blood Preservation / Q000379:methods*; D001952:Bridged-Ring Compounds / Q000097:blood*; D004355:Drug Stability; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D013048:Specimen Handling; D013696:Temperature; D013997:Time Factors
D001952:Bridged-Ring Compounds; C010349:tetramethylenedisulfotetramine