Autosomal dominant polycystic kidney disease and transplantation.
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder affecting 1 in 1,000 people and responsible for 10% of cases of the end stage renal disease (ESRD). Apart from renal manifestations, changes in other organs may be present. In the absence of contraindications, patients with ADPKD and ESRD should be referred to renal transplantation. The ADPKD patient may also need liver transplantation, or combined liver and kidney transplantation. Also, the patient with ADPKD may become a potential organ donor. The aim of our paper is to review the problems that the physicians deal with in ADPKD patients in pre- and post-transplant period.
Niemczyk
Mariusz
M
Department of Immunology, Transplant Medicine and Internal Diseases; Medical University of Warsaw, Poland. mariuszniemczyk@wp.pl
Niemczyk
Stanisław
S
Paczek
Leszek
L
D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications / Q000601:surgery*; D011184:Postoperative Period; D057234:Preoperative Period