Treatment of HIV-related inflammatory cerebral cryptococcoma with adalimumab.
Cryptococcomas have been described in AIDS patients in the setting of immune reconstitution inflammatory syndrome. We report the first case of human immunodeficiency virus-related inflammatory cerebral cryptococcoma to be treated with a recombinant human monoclonal tumor necrosis factor antagonist.
Sitapati
Amy M
AM
Departments of Medicine, University of California, San Diego School of Medicine, San Diego, USA. asitapati@ucsd.edu
Kao
Cynthia L
CL
Cachay
Edward R
ER
Masoumi
Homeyra
H
Wallis
Robert S
RS
Mathews
W Christopher
WC
D000068879:Adalimumab; D000328:Adult; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D016919:Meningitis, Cryptococcal / Q000188:drug therapy* / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab