title: Lifestyle management improves quality of life and depression in overweight and obese women with polycystic ovary syndrome.
abstract: OBJECTIVE
  To assess the impact of adding exercise to dietary restriction on depressive symptoms and health-related quality of life (HRQOL) in women with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Analysis of depression and quality of life outcomes from a randomized, controlled prospective clinical intervention that evaluated the effects on a range of health outcomes in women with PCOS.
  
  
  METHODS
  Clinical research unit.
  
  
  METHODS
  One hundred four overweight/obese PCOS women (aged 29.3 ± 0.7 years; body mass index [BMI] 36.1 ± 0.5 kg/m(2)).
  
  
  METHODS
  Randomized to one of three 20-week lifestyle programs: diet only, diet and aerobic exercise, or diet and combined aerobic-resistance exercise.
  
  
  METHODS
  Depression and PCOS-specific HRQOL.
  
  
  RESULTS
  Forty-nine women completed the intervention (diet only = 14, diet and aerobic exercise = 15, diet and combined aerobic-resistance exercise = 20). By week 20 all groups achieved weight loss and had improvements in depression and PCOS-specific HRQOL scores, except for body hair domain score. There was no difference between treatments for all outcomes.
  
  
  CONCLUSIONS
  This study demonstrated that dietary restriction alone and combined with exercise had similar benefits for improving depression and HRQOL scores in overweight and obese women with PCOS.
authors.affiliation: Australian Technology Network Centre for Metabolic Fitness & Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Thomson
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Buckley
authors.forename: Siew S
authors.initials: SS
authors.lastname: Lim
authors.forename: Manny
authors.initials: M
authors.lastname: Noakes
authors.forename: Peter M
authors.initials: PM
authors.lastname: Clifton
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Norman
authors.forename: Grant D
authors.initials: GD
authors.lastname: Brinkworth
mesh_terms: D000328:Adult; D015897:Comorbidity; D003863:Depression / Q000523:psychology* / Q000628:therapy*; D004032:Diet; D015444:Exercise; D005260:Female; D006306:Health Surveys; D006801:Humans; D008019:Life Style; D009765:Obesity / Q000453:epidemiology / Q000523:psychology*; D050177:Overweight / Q000453:epidemiology / Q000523:psychology*; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology / Q000523:psychology*; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D055070:Resistance Training; D016896:Treatment Outcome