title: Primary seminoma of the prostate.
abstract: Abstract A 54-year-old gentleman was suspected of having sarcoma of the prostate because of his low serum prostate-specific antigen level (1.9 ng/mL) and an enlarged heterogeneous mass on computed tomography and magnetic resonance imaging scans. Pathological examination of the prostate needle biopsy indicated seminoma, which was confirmed with immunohistochemical staining. There was no evidence of disease in other areas on physical examination or on radiographic tests. Therefore, we diagnosed the case as a primary seminoma of the prostate, which was consequently treated with a total of three courses of bleomycin, etoposide and cisplatin chemotherapy. Complete response was obtained on computed tomography, magnetic resonance imaging and prostate needle re-biopsy. To our knowledge, there have only been five cases of primary seminoma of the prostate reported.
authors.affiliation: Department of Urology, Tokyo Medical University, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohori
authors.forename: Noboru
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Jun
authors.initials: J
authors.lastname: Matsubayashi
authors.forename: Miki
authors.initials: M
authors.lastname: Izumi
authors.forename: Masaaki
authors.initials: M
authors.lastname: Tachibana
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001707:Biopsy, Needle; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D018239:Seminoma / Q000188:drug therapy* / Q000473:pathology*
chemical_list: D000903:Antibiotics, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin