Applications of allylsamarium bromide as a grignard reagent and a single-electron transfer reagent in the one-pot synthesis of dienes and trienes.
The utility of allylsamarium bromide, both as a nucleophilic reagent and a single-electron transfer (SET) reagent in the reaction of alpha-halo, gamma-halo-alpha,beta-unsaturated ketones and esters with allylsamarium bromide is reported for the first time in this paper. From a synthetic point of view, a general, efficient and experimentally simple one-pot method for the preparation of 1,4-dienes and trienes is developed. A possible mechanism of the transformation is proposed.
Hu
Yuanyuan
Y
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Dushu Lake Campus Suzhou University, Suzhou, 215123, PR China.
Zhao
Tao
T
Zhang
Songlin
S