One-pot silver-catalyzed and PIDa-mediated sequential reactions: synthesis of polysubstituted pyrroles directly from alkynoates and amines.
The addition/oxidative cyclization of alkynes with amines in the presence of AgBF(4) catalyst and PIDA oxidant leads to polysubstituted pyrroles. The reaction corresponds to the construction of a pyrrole fragment, which also provides a new way to the formation of C-C bonds.
Liu
Weibing
W
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China.
Jiang
Huanfeng
H
Huang
Liangbin
L
D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D000078789:Polyacetylene Polymer; D053279:Polyynes / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D012834:Silver / Q000737:chemistry*
D000480:Alkynes; D000588:Amines; D007659:Ketones; C530010:Poly(diiodiacetylene); D000078789:Polyacetylene Polymer; D011758:Pyrroles; D053279:Polyynes; D012834:Silver