Efficient aerobic Wacker oxidation of styrenes using palladium bis(isonitrile) catalysts.
The palladium-catalyzed aerobic oxidation of alkenes and especially styrenes (Wacker oxidation) by using chiral pseudo C(2)-symmetrical bis(isonitrile) ligands in the absence of further cocatalysts gives rise to methyl ketones in a highly chemoselective manner. The palladium bis(isonitrile) catalyst was characterized by NMR spectroscopy and X-ray structure analysis, revealing a dissymmetric coordination of palladium by the two isonitrile moieties.
Naik
Anu
A
Institut für Organische Chemie, Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.
Meina
Liu
L
Zabel
Manfred
M
Reiser
Oliver
O