Direct arylations of 2H-indazoles on water.
The efficient palladium-catalyzed synthesis of a range of substituted 2H-Indazoles via C-H arylation is reported. Reactions are performed on water and provide a direct and mild route toward 2,3-diaryl indazoles of widespread biological significance.
Ohnmacht
Stephan A
SA
University of Edinburgh, School of Chemistry, Joseph Black Building, King's Buildings, West Mains Rd., Edinburgh EH9 3JJ, UK.
Culshaw
Andrew J
AJ
Greaney
Michael F
MF
D002384:Catalysis; D007191:Indazoles / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D007191:Indazoles; D014867:Water; D010165:Palladium