title: Peritoneal dialysis and hemodialysis in systemic lupus erythematosus patients: comparison of clinical outcomes.
abstract: BACKGROUND
  This study compared peritoneal dialysis (PD) and hemodialysis (HD) outcomes between female systemic lupus erythematosus (SLE) patients with end-stage renal disease (ESRD) due to lupus nephropathy.
  
  
  METHODS
  22 female SLE patients undergoing PD were compared with 14 female SLE patients receiving HD. Clinical outcomes and infective complications were reviewed.
  
  
  RESULTS
  The overall mortality rate was much higher in the PD group (6/22) than in the HD group (1/14) (p = 0.027). PD patients had higher C-reactive protein level (37.1 +/- 41.4 vs. 6.7 +/- 9.5 mg/l, p = 0.037) and numbers of infectious episode (PD vs. HD: 1 episode per 33.16 patient-months vs. 1 episode per 118.26 patient-months, respectively, p = 0.046). Before the end of the observation period, HD patients had higher serum albumin (3.8 +/- 0.2 vs. 3.3 +/- 0.6 g/dl, p = 0.01).
  
  
  CONCLUSIONS
  In female SLE patients with ESRD due to lupus nephropathy, clinical outcomes are better after undergoing HD than after undergoing PD.
authors.affiliation: Department of Nephrology, Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taoyuan, Taiwan, ROC.
authors.forename: Cheng-Hao
authors.initials: CH
authors.lastname: Weng
authors.forename: Ching-Wei
authors.initials: CW
authors.lastname: Hsu
authors.forename: Chun-Chen
authors.initials: CC
authors.lastname: Yu
authors.forename: Tzung-Hai
authors.initials: TH
authors.lastname: Yen
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Yang
authors.forename: Cheng-Chieh
authors.initials: CC
authors.lastname: Hung
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D002423:Cause of Death; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007239:Infections / Q000150:complications; D053208:Kaplan-Meier Estimate; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D012189:Retrospective Studies; D012709:Serum Albumin / Q000378:metabolism; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D012709:Serum Albumin; D002097:C-Reactive Protein