Two cases of bovine male pseudohermaphrodites with different endocrinological and pathological findings.
Two cases of bovine male pseudohermaphrodites (PH) were subjected for clinical investigation with transrectal ultrasonography, endocrinology with adoption of hCG-stimulation test, cytogenetics with analysis of sex chromosome and Y-specific DNA, and finally histological examination. Results were compared with normal calves. Case 1 was a 10-month-old calf with XX/XY chimeras, showing elevation of testosterone (T) levels, but no change in progesterone (P(4)) after hCG test, and possessed atrophied testes in the cavitas pelvis. Case 2 was an 18-month-old calf with SRY positive-XY chromosome, showing lower level of plasma T and P(4) after hCG test, and possessed atrophied testes and undifferentiated genital ducts. Both cases possessed female-like external genitalia with similar pathological findings, however endocrinological and cytogenetical aspects were different each other.
Moriyama
Chiho
C
Department of Clinical Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University.
Tani
Mineto
M
Nibe
Kazumi
K
Kitahara
Go
G
Haneda
Shingo
S
Matsui
Motozumi
M
Miyake
Yoh-Iichi
YI
Kamimura
Shunichi
S
D000818:Animals; D002417:Cattle / Q000033:anatomy & histology*; D002418:Cattle Diseases / Q000235:genetics* / Q000473:pathology*; D004247:DNA / Q000235:genetics; D017931:DNA Primers; D012734:Disorders of Sex Development / Q000235:genetics* / Q000473:pathology / Q000662:veterinary*; D005260:Female; D024282:Genes, sry; D005836:Genitalia, Female / Q000033:anatomy & histology; D007985:Leydig Cells / Q000473:pathology; D008297:Male; D016133:Polymerase Chain Reaction; D012671:Seminiferous Tubules / Q000033:anatomy & histology / Q000473:pathology; D013091:Spermatogenesis; D014998:Y Chromosome
D017931:DNA Primers; D004247:DNA