title: Hospital readmission in general medicine patients: a prediction model.
abstract: BACKGROUND
  Previous studies of hospital readmission have focused on specific conditions or populations and generated complex prediction models.
  
  
  OBJECTIVE
  To identify predictors of early hospital readmission in a diverse patient population and derive and validate a simple model for identifying patients at high readmission risk.
  
  
  METHODS
  Prospective observational cohort study.
  
  
  METHODS
  Participants encompassed 10,946 patients discharged home from general medicine services at six academic medical centers and were randomly divided into derivation (n = 7,287) and validation (n = 3,659) cohorts.
  
  
  METHODS
  We identified readmissions from administrative data and 30-day post-discharge telephone follow-up. Patient-level factors were grouped into four categories: sociodemographic factors, social support, health condition, and healthcare utilization. We performed logistic regression analysis to identify significant predictors of unplanned readmission within 30 days of discharge and developed a scoring system for estimating readmission risk.
  
  
  RESULTS
  Approximately 17.5% of patients were readmitted in each cohort. Among patients in the derivation cohort, seven factors emerged as significant predictors of early readmission: insurance status, marital status, having a regular physician, Charlson comorbidity index, SF12 physical component score, >or=1 admission(s) within the last year, and current length of stay >2 days. A cumulative risk score of >or=25 points identified 5% of patients with a readmission risk of approximately 30% in each cohort. Model discrimination was fair with a c-statistic of 0.65 and 0.61 for the derivation and validation cohorts, respectively.
  
  
  CONCLUSIONS
  Select patient characteristics easily available shortly after admission can be used to identify a subset of patients at elevated risk of early readmission. This information may guide the efficient use of interventions to prevent readmission.
authors.affiliation: Division of General Internal Medicine, Brigham and Women's Hospital, 1620 Tremont Street, 3rd Floor, Boston, MA 02120-1613, USA.
authors.forename: Omar
authors.initials: O
authors.lastname: Hasan
authors.forename: David O
authors.initials: DO
authors.lastname: Meltzer
authors.forename: Shimon A
authors.initials: SA
authors.lastname: Shaykevich
authors.forename: Chaim M
authors.initials: CM
authors.lastname: Bell
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Kaboli
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Auerbach
authors.forename: Tosha B
authors.initials: TB
authors.lastname: Wetterneck
authors.forename: Vineet M
authors.initials: VM
authors.lastname: Arora
authors.forename: James
authors.initials: J
authors.lastname: Zhang
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Schnipper
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005194:Family Practice / Q000379:methods / Q000639:trends*; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D010359:Patient Readmission / Q000639:trends*; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult