title: Evaluation of the hemodynamic impact of continuous renal replacement therapy in healthy dogs.
abstract: We performed continuous renal replacement therapy (CRRT) on clinically healthy dogs to evaluate the effects of CRRT on hemodynamics. Heart rate, arterial blood pressure, and central venous pressure of the dogs (n=6) were recorded during the procedure, which was performed under general anesthesia. Throughout the CRRT, heart rate and arterial blood pressure were stable. Central venous pressure increased after CRRT termination but returned to the basal level within 30 min. In this study, hemodynamic alterations, including hypotension, hypertension, and arrhythmias, were not observed during CRRT. These observations suggest that the CRRT protocol used in the present study can be safely applied to clinical cases with acute renal failure.
authors.affiliation: Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University.
authors.forename: Takako
authors.initials: T
authors.lastname: Shimokawa Miyama
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Itamoto
authors.forename: Chihiro
authors.initials: C
authors.lastname: Yoshioka
authors.forename: Koji
authors.initials: K
authors.lastname: Minami
authors.forename: Takumi
authors.initials: T
authors.lastname: Okawa
authors.forename: Yuka
authors.initials: Y
authors.lastname: Fujisaki
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hiraoka
authors.forename: Takuya
authors.initials: T
authors.lastname: Mizuno
authors.forename: Masaru
authors.initials: M
authors.lastname: Okuda
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary; D000818:Animals; D001794:Blood Pressure; D002496:Central Venous Pressure; D003971:Diastole; D004285:Dogs; D005260:Female; D006339:Heart Rate; D017583:Hemodiafiltration / Q000379:methods / Q000662:veterinary*; D006439:Hemodynamics / Q000502:physiology*; D012016:Reference Values; D017582:Renal Replacement Therapy / Q000379:methods / Q000662:veterinary*; D013599:Systole