Percutaneous radionuclide ablation of axial aneurysmal bone cysts.
OBJECTIVE
The purpose of our study was to retrospectively examine the efficacy of intralesional injection of 32P chromic phosphate, a beta-emitting colloidal radiopharmaceutical, in the treatment of aneurysmal bone cysts of the axial skeleton. Five patients with large aneurysmal bone cysts were managed with injection of 32P chromic phosphate into their tumors under CT guidance. With only a single minor complication, all lesions were observed to ossify on follow-up CT, with an average follow up of 2 years.


CONCLUSIONS
CT-guided injection of axial aneurysmal bone cysts with 32P chromic phosphate leads to excellent local lesion control. In addition, the morbidity associated with this procedure is lower than that associated with surgical or other nonsurgical treatments.
Bush
Charles H
CH
Department of Radiology, University of Florida College of Medicine, 1600 SW Archer Rd., PO Box 100374, Gainesville, FL 32610, USA. bushch@radiology.ufl.edu
Adler
Zachary
Z
Drane
Walter E
WE
Tamurian
Robert
R
Scarborough
Mark T
MT
Gibbs
Charles P
CP
D000293:Adolescent; D017824:Bone Cysts, Aneurysmal / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D002648:Child; D017608:Chromium Compounds / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D010710:Phosphates / Q000627:therapeutic use*; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use*; D015641:Radiography, Interventional; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
D017608:Chromium Compounds; D010710:Phosphates; D010761:Phosphorus Radioisotopes; D019275:Radiopharmaceuticals; C509369:chromic phosphate