title: [Phyllodes tumour: a rare, rapidly growing breast tumour].
abstract: A 40-year-old woman presented at the breast outpatient clinic with a giant tumour of her left breast. The size, rapid growth and radiological characteristics of the lesion led us to suspect a phyllodes tumour. A histological examination of a needle biopsy confirmed this diagnosis. An additional CT scan revealed no signs of metastases. We performed a mastectomy during which a tumour measuring 48 x 33 x 25 cm was resected. Histological examination revealed a borderline phyllodes tumour. Phyllodes tumours are rare fibroepithelial neoplasms of the breast and pre-operatively these are often difficult to differentiate from fibroadenomas. Phyllodes tumours have a variable clinical course with the ability to metastasize and a propensity to recur locally. Complete excision with wide margins is essential to prevent local recurrence. In our case, the surgical margins were limited and our patient was therefore treated with postoperative radiation therapy.
authors.affiliation: Diaconessenhuis, afd. Chirurgie, Leiden, The Netherlands. pauldenexter@gmail.com
authors.forename: Paul L
authors.initials: PL
authors.lastname: den Exter
authors.forename: Bonne J
authors.initials: BJ
authors.lastname: Hornstra
authors.forename: Robbert
authors.initials: R
authors.lastname: Vree
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008408:Mastectomy; D009362:Neoplasm Metastasis; D003557:Phyllodes Tumor / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D016896:Treatment Outcome