title: Factors related to elevated 24-h blood pressure in young adults.
abstract: Variation in 24-h blood pressure (BP) is associated with multiple factors, but the association has not been thoroughly examined in young adults. To elucidate the potential factors associated with variation in 24-h BP, 331 healthy medical students were investigated. Awake mean BP negatively correlated with sleep duration in males. Sixty-seven subjects (20.2%) had a high 24-h BP according to the ESH/ESC 2007 guidelines (systolic blood pressure (SBP) 125 and/or diastolic blood pressure (DBP) 80 mmHg). After multivariate analysis for confounding factors, male gender, body mass index (BMI), smoking, the 24-h low/high frequency component (heart rate variability spectral analysis), and short sleep (5 h or less) were found to be associated with high BP. The present study is the first to demonstrate the multivariate risk factors for elevated 24-h BP in a large number of young adults. Further investigation is required to determine the causal relationship between modifiable BP-related factors and elevated 24-h BP in young adults.
authors.affiliation: Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku,Yokohama, Japan. t066033c@yokohama-cu.ac.jp
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Fujikawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Tochikubo
authors.forename: Naoki
authors.initials: N
authors.lastname: Kura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemura
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D018660:Blood Pressure Monitoring, Ambulatory; D015992:Body Mass Index; D002940:Circadian Rhythm; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D015999:Multivariate Analysis; D005082:Physical Exertion; D012307:Risk Factors; D017678:Sex Distribution; D012892:Sleep Deprivation; D012907:Smoking; D013337:Students, Medical / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D014851:Wakefulness; D055815:Young Adult