Carbapenem susceptibility patterns for clinical isolates of Mycobacterium abscessus determined by the Etest method.
Mycobacterium abscessus is resistant to multiple antibiotics, creating treatment challenges. Carbapenems are tested to increase therapeutic alternatives. We performed in vitro susceptibility testing by Etest of four carbapenems for M. abscessus isolates. Imipenem demonstrated the most in vitro activity, and testing of other carbapenems provided no additional value.
Chihara
Shingo
S
University of Utah School of Medicine, Department of Pathology, Salt Lake City, Utah, USA. schihara@dokkyomed.ac.jp
Smith
Geremy
G
Petti
Cathy A
CA
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015780:Carbapenems / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects* / Q000302:isolation & purification; D009164:Mycobacterium Infections / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D015780:Carbapenems