title: The Prevalence of Vitamin D Deficiency Is Similar between Thyroid Nodule and Thyroid Cancer Patients.
abstract: Introduction. There are reported associations between vitamin D deficiency and breast, prostate, and colon cancer, but the relationship in thyroid cancer has not been evaluated. Methods. We evaluated serum calcium, creatinine, albumin, and 25-hydroxy vitamin D (25-OH-D) in 42 thyroid nodule, 45 thyroid cancer in remission, and 24 active thyroid cancer patients. Results. 25-OH-D was not different between groups. The percent with 25-OH-D levels <75 nmol/L was not significantly different between groups and was not affected by season of measurement, age, or cancer stage. Multivariate regression showed a BMI of >/=30 kg/m(2) to be the only significant predictor of vitamin D deficiency. Conclusions. Rates of vitamin D deficiency are similar in thyroid nodules and thyroid cancer, although higher than the general population. This is different than previous studies for other cancers, which show higher rates of vitamin D deficiency. BMI was the only predictor of vitamin D deficiency.
authors.affiliation: Department of Internal Medicine, Section of Diabetes, Endocrinology, and Metabolism, University of Nebraska Medical Center, Omaha, NE 68198-3020, USA.
authors.forename: Nathan
authors.initials: N
authors.lastname: Laney
authors.forename: Jane
authors.initials: J
authors.lastname: Meza
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Lyden
authors.forename: Judi
authors.initials: J
authors.lastname: Erickson
authors.forename: Kelly
authors.initials: K
authors.lastname: Treude
authors.forename: Whitney
authors.initials: W
authors.lastname: Goldner