title: [Experience from surgical resection for 48 cases of hilar cholangiocarcinoma].
abstract: OBJECTIVE
  To summarize the methods, safety and efficiency of surgical resection for hilar cholangiocarcinoma.
  
  
  METHODS
  The clinical and follow-up data of 48 patients with hilar cholangiocarcinoma underwent surgical resection from January 2003 to December 2007 were analyzed retrospectively. There were 26 male and 22 female, aged from 38 to 72 years old with a mean of 63.6 years old.
  
  
  RESULTS
  Perioperative management including percutaneous transhepatic biliary drainage applied in 19 cases and portal vein embolization applied in 2 cases. Eight patients were treated with extrahepatic bile duct resection with or without parital hepatic segment II resection, 10 cases with perihilar hepatic resection (segment IVB, partial V, partial VIII, I), 28 cases with extended hemihepatectomy and 2 cases with central hepatic resection (segment IVB, V, VIII, I). R0 resection rate was 89.5% and the operative mortality was 2.1%. The 1-, 3- and 5-year survival rate were 93.5%, 51.8% and 36.5%, respectively. Patients undergoing extended hepatic resection survived significantly longer than those undergoing partial hepatic resection (P = 0.034).
  
  
  CONCLUSIONS
  Extended hepatic resection for hilar cholangiocarcinoma offers good outcomes with an acceptable mortality rate.
authors.affiliation: Department of Hepatobiliary Surgery, General Hospital of People's Liberation Army, Beijing 100853, China. caisw8077.cai@vip.sina.com
authors.forename: Shou-wang
authors.initials: SW
authors.lastname: Cai
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Duan
authors.forename: Zhe
authors.initials: Z
authors.lastname: Liu
authors.forename: Xiang-qian
authors.initials: XQ
authors.lastname: Zhao
authors.forename: Wen-zhi
authors.initials: WZ
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Xiao-qiang
authors.initials: XQ
authors.lastname: Huang
authors.forename: Jia-hong
authors.initials: JH
authors.lastname: Dong
authors.forename: Zhi-qiang
authors.initials: ZQ
authors.lastname: Huang
mesh_terms: D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome