title: Stereoselective synthesis of trans-beta-lactams by palladium-catalysed carbonylation of vinyl aziridines.
abstract: The palladium-catalysed carbonylation of vinyl aziridines can give either the trans- or cis-beta-lactam preferentially or even the delta-lactam simply by adjusting the reaction parameters ([Pd], [CO], temperature).
authors.affiliation: School of Chemistry, Cantock's Close, Bristol, UK.
authors.forename: Francesco
authors.initials: F
authors.lastname: Fontana
authors.forename: Gian Cesare
authors.initials: GC
authors.lastname: Tron
authors.forename: Nekane
authors.initials: N
authors.lastname: Barbero
authors.forename: Serena
authors.initials: S
authors.lastname: Ferrini
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Thomas
authors.forename: Varinder K
authors.initials: VK
authors.lastname: Aggarwal
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature; D014753:Vinyl Compounds / Q000737:chemistry*; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001388:Aziridines; D014753:Vinyl Compounds; D047090:beta-Lactams; D010165:Palladium; D002244:Carbon