title: Solvent-resistant nanofiltration for product purification and catalyst recovery in click chemistry reactions.
abstract: The quickly developing field of "click" chemistry would undoubtedly benefit from the availability of an easy and efficient technology for product purification to reduce the potential health risks associated with the presence of copper in the final product. Therefore, solvent-resistant nanofiltration (SRNF) membranes have been developed to selectively separate "clicked" polymers from the copper catalyst and solvent. By using these solvent-stable cross-linked polyimide membranes in diafiltration, up to 98 % of the initially present copper could be removed through the membrane together with the DMF solvent, the polymer product being almost completely retained. This paper also presents the first SRNF application in which the catalyst permeates through the membrane and the reaction product is retained.
authors.affiliation: Centre for Surface Chemistry and Catalysis, Faculty of Bioscience Engineering, Katholieke Universiteit Leuven, Kasteelpark Arenberg 23, Box 2461, 3001 Leuven, Belgium.
authors.forename: Angels
authors.initials: A
authors.lastname: Cano-Odena
authors.forename: Pieter
authors.initials: P
authors.lastname: Vandezande
authors.forename: David
authors.initials: D
authors.lastname: Fournier
authors.forename: Wim
authors.initials: W
authors.lastname: Van Camp
authors.forename: Filip E
authors.initials: FE
authors.lastname: Du Prez
authors.forename: Ivo F J
authors.initials: IF
authors.lastname: Vankelecom
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D005374:Filtration / Q000379:methods*; D036103:Nanotechnology; D012117:Resins, Synthetic / Q000737:chemistry; D012997:Solvents / Q000737:chemistry*
chemical_list: D012117:Resins, Synthetic; D012997:Solvents; C029945:polyimide resin; D003300:Copper