title: Antimicrobial efficacy assessment of multi-use solution to disinfect hydrophilic contact lens, in vitro.
abstract: OBJECTIVE
  To evaluate the efficacy of disinfecting solutions in hydrophilic contact lenses (CL).
  
  
  METHODS
  Two multi-use solutions denominated solution A (0.001% polyquaternium-1 and 0.0005% myristamidopropyl dimethylamine) and solution B (0.0001% polyaminopropyl biguanide) were used. The solutions were tested in hydrophilic contact lenses infected with Pseudomonas aeruginosa (ATCC27583), Staphylococcus epidermidis (ATCC1226), Klebsiella pneumoniae (ATCC13883), Staphylococcus aureus (ATCC25923) and Candida albicans (ATCC 10231) and the decrease in microorganisms growth after the hydrophilic contact lenses were cleaned with the respective solutions was verified. The manufacture's instructions were followed.
  
  
  RESULTS
  A decrease of 90% of Pseudomonas aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus, Candida albicans and a decrease 100% of Klebsiella pneumoniae was observed.
  
  
  CONCLUSIONS
  The solutions decreased the amount of microorganisms tested.
authors.affiliation: Departamento de Oftalmologia, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil. acflui@yahoo.com.br
authors.forename: Aline Cristina Fioravanti
authors.initials: AC
authors.lastname: Lui
authors.forename: Adamo Lui
authors.initials: AL
authors.lastname: Netto
authors.forename: Cely Barreto da
authors.initials: CB
authors.lastname: Silva
authors.forename: Richard
authors.initials: R
authors.lastname: Hida
authors.forename: Thais Sousa
authors.initials: TS
authors.lastname: Mendes
authors.forename: Giovana Arlene Fioravanti
authors.initials: GA
authors.lastname: Lui
authors.forename: Daniela Barbosa
authors.initials: DB
authors.lastname: Gemperli
authors.forename: Enderson Dantas
authors.initials: ED
authors.lastname: Vital
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D001645:Biguanides / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D015169:Colony Count, Microbial; D018639:Contact Lens Solutions / Q000494:pharmacology*; D003263:Contact Lenses, Hydrophilic / Q000382:microbiology*; D004202:Disinfectants / Q000494:pharmacology*; D007709:Klebsiella / Q000187:drug effects / Q000254:growth & development; D011108:Polymers / Q000494:pharmacology; D011437:Propylamines / Q000494:pharmacology / Q000592:standards; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000254:growth & development
chemical_list: D001645:Biguanides; D018639:Contact Lens Solutions; D004202:Disinfectants; D011108:Polymers; D011437:Propylamines; C064420:polyaminopropylbiguanide; C058655:polyquaternium 1; C401661:myristamidopropyl dimethylamine