Posttraumatic psoriatic osteitis of the frontal bone successfully treated with etanercept. Report of a case.
We report a case of aseptic osteomyelitis of the frontal bone that developed after a local injury in an 8-year-old girl with psoriasis of the scalp as a predisposing factor. Follow-up was 36 years (1972 to 2008). Enthesitis of the forehead muscles was a plausible pathophysiological mechanism. The symptoms responded to anti-inflammatory medications and resolved immediately after the introduction of etanercept therapy. The most interesting feature of this case of psoriatic osteomyelitis is the involvement of a skull bone.
Fournié
Bernard
B
Service de clinique de rhumatologie, CHU Purpan, place Baylac, TSA 40070, 31059 Toulouse cedex 9, France. fournie.b@chu-toulouse.fr
Zabraniecki
Laurent
L
Lemaire
Olivia
O
Plaut-Gaty
Marie-Anne
MA
Poix-Jover
Elsa
E
D000082:Acetaminophen / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D006259:Craniocerebral Trauma / Q000150:complications / Q000473:pathology*; D004359:Drug Therapy, Combination; D000068800:Etanercept; D005260:Female; D005500:Follow-Up Studies; D005624:Frontal Bone / Q000293:injuries / Q000473:pathology; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D010000:Osteitis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D018124:Receptors, Tumor Necrosis Factor; D000082:Acetaminophen; D000068800:Etanercept; D011241:Prednisone; D007052:Ibuprofen