title: Only the good die young: a novel paradigm for mosquito control.
abstract: Andrew Read and colleagues have proposed that insecticides acting late in the vector lifetime are less susceptible to evolutionary pressures, thereby avoiding insecticide resistance. Such late-life acting insecticides would kill the vector before the pathogen's extrinsic cycle is complete, but allow the vector to remain reproductively active. Some examples of late-life acting insecticides are discussed. By targeting older vectors, the dangerous cohorts--those capable of transmitting the fully developed pathogen--are removed.
authors.affiliation: Sanaria Inc., 9800 Medical Center Drive, Rockville, MD 20850, USA. pbillingsley@sanaria.com
authors.forename: Peter F
authors.initials: PF
authors.lastname: Billingsley
mesh_terms: D000818:Animals; D005075:Biological Evolution; D009033:Culicidae / Q000187:drug effects* / Q000235:genetics; D007303:Insect Vectors; D007305:Insecticide Resistance / Q000235:genetics; D007306:Insecticides / Q000494:pharmacology*; D009032:Mosquito Control
chemical_list: D007306:Insecticides