title: Exercise and fitness are related to peripheral nervous system function in overweight adults.
abstract: OBJECTIVE
  This study examined the association between physical activity and fitness and peripheral nervous system (PNS) function in overweight and obese individuals.
  
  
  METHODS
  Forty nondiabetic overweight adults (mean +/- SD; age = 44 +/- 11 yr) were recruited for the study. Peroneal motor nerve and radial, sural, and medial plantar sensory nerve conductions were studied. Maximal oxygen uptake was measured in an incremental bicycle ergometer test. Physical activity was assessed by accelerometer and self-reporting. We analyzed the data using multiple stepwise linear regression models adjusted for age, height, and skin temperature.
  
  
  RESULTS
  VO2max predicted 17% of peroneal distal compound muscle action potential (CMAP) amplitude variation and 16% of peroneal proximal CMAP amplitude variation. Physical activity index at the age of 30 yr predicted 9% of peroneal motor nerve conduction velocity (NCV), 8% of peroneal F-wave maximum latency, 14% of medial plantar sensory latency, and 10% of medial plantar sensory NCV variation.
  
  
  CONCLUSIONS
  Physical activity and fitness are positively associated with PNS function and should be encouraged in overweight people.
authors.affiliation: Department of Medical Technology, Institute of Biomedicine, University of Oulu, Oulu, Finland. henriiso@paju.oulu.fi
authors.forename: Henri
authors.initials: H
authors.lastname: Isojärvi
authors.forename: Sirkka
authors.initials: S
authors.lastname: Keinänen-Kiukaanniemi
authors.forename: Mika
authors.initials: M
authors.lastname: Kallio
authors.forename: Kaisu
authors.initials: K
authors.lastname: Kaikkonen
authors.forename: Timo
authors.initials: T
authors.lastname: Jämsä
authors.forename: Juha
authors.initials: J
authors.lastname: Korpelainen
authors.forename: Raija
authors.initials: R
authors.lastname: Korpelainen
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory; D009765:Obesity / Q000150:complications* / Q000503:physiopathology; D010101:Oxygen Consumption / Q000502:physiology*; D017933:Peripheral Nervous System / Q000502:physiology*; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000503:physiopathology; D010809:Physical Fitness / Q000502:physiology*