title: Prognostic role of tumor size in childhood cancer.
abstract: Identifying prognostic factors that influence outcome is a key point in pediatric oncology, as it enables risk stratification and helps us to fine-tune risk-adapted treatments, thereby hopefully improving the chances of survival for high-risk patients, and minimizing the burden of treatment for those whose outlook is good. Along with other clinical and biological variables, tumor size at onset has been identified as a crucial variable in several pediatric malignancies, and in soft-tissue sarcomas in particular. This review provides a critical reappraisal of the prognostic role of tumor size in pediatric soft-tissue sarcomas.
authors.affiliation: Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milano, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Favini
authors.forename: Iyad
authors.initials: I
authors.lastname: Sultan
authors.forename: Cristina
authors.initials: C
authors.lastname: Meazza
authors.forename: Michela
authors.initials: M
authors.lastname: Casanova
authors.forename: Andrea
authors.initials: A
authors.lastname: Ferrari
mesh_terms: D049628:Body Size; D002648:Child; D006801:Humans; D011379:Prognosis; D012307:Risk Factors; D012509:Sarcoma / Q000401:mortality* / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000401:mortality* / Q000473:pathology*