Effect of trabeculectomy on intraocular pressure fluctuation with postural change in eyes with open-angle glaucoma.
OBJECTIVE
To investigate the effect of trabeculectomy on the intraocular pressure (IOP) fluctuations caused by the postural change in patients with open-angle glaucoma.


METHODS
Prospective, nonrandomized study. Ten eyes of 10 patients with primary open-angle glaucoma and 3 eyes of 3 patients with normal-tension glaucoma who underwent trabeculectomy were studied. The IOP at the baseline and 3 months after trabeculectomy was measured in both sitting and supine positions. A pneumatonometer was used to measure the IOP in both sitting and supine position.


RESULTS
The mean IOP in the sitting position was 19.6+/-5.1 mm Hg at the baseline and 9.4+/-2.9 mm Hg after trabeculectomy (P<0.01, paired t test). The mean difference in IOP between the sitting and supine position was 4.1+/-1.6 mm Hg at the baseline and 2.2+/-1.5 mm Hg after trabeculectomy (P=0.01, paired t test).


CONCLUSIONS
Trabeculectomy might decrease not only the IOP in the sitting position but also the magnitude of IOP elevation associated with the postural change.
Hirooka
Kazuyuki
K
Department of Ophthalmology, Kagawa University Faculty of Medicine, Ikenobe, Miki, Kagawa, Japan. kazuyk@med.kagawa-u.ac.jp
Takenaka
Hirokazu
H
Baba
Tetsuya
T
Takagishi
Mai
M
Mizote
Masanori
M
Shiraga
Fumio
F
D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D011187:Posture / Q000502:physiology*; D011446:Prospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy