[VEGF and central nervous system diseases].
Vascular endothelial growth factor (VEGF or VEGF-A) is a hypoxia induced angiogenic growth factor that is potent in neurotrophy,neuroprotection, anti-apoptosis and cell proliferation. Recent reports suggest that VEGF is related to many central nervous system diseases, such as cerebral ischemic disease, Alzheimer's disease and Parkinson's disease. Further study of the relationship between VEGF and central nervous system diseases,and investigation of VEGF related drugs will shed light on a new way for treatment of central nervous system diseases.
Zhang
Lu-Yi
LY
Department of Pharmacology, College of Medicine, Zhejiang University, Hangzhou 310058, China.
Fan
Yan-Ying
YY
Liu
Zhong
Z
D000544:Alzheimer Disease / Q000378:metabolism*; D000818:Animals; D002545:Brain Ischemia / Q000378:metabolism*; D006801:Humans; D018696:Neuroprotective Agents / Q000494:pharmacology; D010300:Parkinson Disease / Q000378:metabolism*; D042461:Vascular Endothelial Growth Factor A / Q000145:classification / Q000378:metabolism / Q000502:physiology*
D018696:Neuroprotective Agents; D042461:Vascular Endothelial Growth Factor A