Chiral silica-based monoliths in chromatography and capillary electrochromatography.
Chiral-modified silica-based monoliths have become well-established stationary phases for both high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The silica-based monoliths were fabricated either in situ in the capillaries for nano-HPLC and CEC or in a mould for "conventional" HPLC. The present review summarizes the chiral modification of silica monoliths and the recent development in the field of enantioselective separations by nano-HPLC and CEC.
Wistuba
Dorothee
D
Institute of Organic Chemistry, University of Tübingen, 72076 Tübingen, Germany. dorothee.wistuba@orgchem.uni-tuebingen.de
D053801:Capillary Electrochromatography / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003505:Cyclodextrins / Q000737:chemistry; D011506:Proteins / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*; D013237:Stereoisomerism
D003505:Cyclodextrins; D011506:Proteins; D012822:Silicon Dioxide