title: [Poorly differentiated stomach adenocarcinoma combined with jejunal stromal tumour. Clinical study].
abstract: Gastrointestinal stromal tumours (GIST) first described in 1983 are the commonest mesenchymal neoplsams of the digestive tract. The main pathogenetic mechanism is hypersecretion of tyrosin kinase receptor c-kit (CD-117) by GIST cells and its hyperactivation. A rare clinical case of GIST measuring 1.2 CM with concomitant stomach cancer (poorly differentiated carcinoma) is reported. The tumours were discovered intraoperatively. To our knowledge, data on such cases are practically lacking in the literature.
authors.forename: V B
authors.initials: VB
authors.lastname: Simonenko
authors.forename: M I
authors.initials: MI
authors.lastname: Vasil'chenko
authors.forename: D V
authors.initials: DV
authors.lastname: Zykov
authors.forename: V S
authors.initials: VS
authors.lastname: Lesovik
authors.forename: M A
authors.initials: MA
authors.lastname: Makanin
authors.forename: P A
authors.initials: PA
authors.lastname: Dulin
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D005743:Gastrectomy / Q000379:methods; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007580:Jejunal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed