Adrenal failure caused by a retroperitoneal malignant mesothelioma.
A 62-year-old man presented with clinical signs of acute abdominal pain and adrenal insufficiency. Computerized tomographic scans revealed bilateral adrenal tumors and the left adrenal tumor was surgically resected. The patient was found to have retroperitoneal mesothelioma presenting as bilateral metastatic adrenal tumors, which were well controlled by systemic chemotherapy with CDDP and 5-FU. This case appears to be the first reported case in the literature of adrenal failure due to bilateral adrenal infiltration caused by retroperitoneal malignant mesothelioma.
Nomura
Masatoshi
M
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University. nomura@med.kyushu-u.ac.jp
Sasano
Hironobu
H
Okada
Yasuyo
Y
Watanabe
Tetsuhiro
T
Sakamoto
Shohei
S
Sakiyama
Yumiko
Y
Sakamoto
Ryuichi
R
Abe
Ichiro
I
Horiuchi
Toshihiro
T
Yanase
Toshihiko
T
Takayanagi
Ryoichi
R
D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D000309:Adrenal Insufficiency / Q000209:etiology*; D000971:Antineoplastic Combined Chemotherapy Protocols; D002945:Cisplatin / Q000627:therapeutic use; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*
D002945:Cisplatin; D005472:Fluorouracil