title: Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.
abstract: OBJECTIVE
  To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP).
  
  
  METHODS
  We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery, type of surgery, duodenal polyps and colorectal cancer at surgery were analyzed.
  
  
  RESULTS
  During WCE, polyps were detected in 9/14 (64.3%) patients. Duodenal adenomatous polyps were found in nine (64.3%) patients, and jejunal and ileal polyps in seven (50%) and eight (57.1%), respectively. The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps. Identification of the ampulla of Vater was not achieved with WCE. Importantly, the findings of WCE had no immediate impact on the further clinical management of FAP patients. No procedure-related complications were observed in the patients.
  
  
  CONCLUSIONS
  WCE is a promising noninvasive new method for the detection of small-intestinal polyps. Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.
authors.affiliation: Department of Endoscopy and Motility Unit, Central Hospital, Ethnikis Aminis 41, 54635, Thessaloniki, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Katsinelos
authors.forename: Jannis
authors.initials: J
authors.lastname: Kountouras
authors.forename: Grigoris
authors.initials: G
authors.lastname: Chatzimavroudis
authors.forename: Christos
authors.initials: C
authors.lastname: Zavos
authors.forename: Ioannis
authors.initials: I
authors.lastname: Pilpilidis
authors.forename: Kostas
authors.initials: K
authors.lastname: Fasoulas
authors.forename: George
authors.initials: G
authors.lastname: Paroutoglou
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000473:pathology*; D000328:Adult; D053704:Capsule Endoscopy; D005260:Female; D006115:Greece; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis* / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult