title: Endonasal phototherapy with Rhinolight for the treatment of allergic rhinitis.
abstract: Allergic rhinitis, although not life threatening, significantly affects the quality of the patient's daily life. The three major steps in the treatment of the condition are avoidance of allergens, treatment of symptoms (in particular, antihistaminics and topical nasal corticosteroids) and specific immunotherapy. Avoidance of the allergen is usually not possible and symptom relief is often limited, despite the availability of a number of pharmacological options. Specific immunotherapy demands a high level of cooperation on the part of the patient for at least 3 years. Endonasal phototherapy with the Rhinolight device (Rhinolight Ltd, Szeged, Hungary) for the treatment of immunoglobulin E-mediated allergic rhinitis is a new option that utilizes the immunosuppressive effects of UV radiation. The method directs a combination of UV-B (5%), UV-A (25%) and visible light (70%) into the nasal cavity, and its effectiveness has been demonstrated in one double-blind, placebo-controlled study. The results of additional studies have been presented at various medical conferences and in abstracts. Reports in the literature confirm that phototherapy is a well-established and successful treatment of atopic dermatitis and other skin diseases.
authors.affiliation: University of Witten/Herdecke, Faculty of Medicine, Friedrichstrasse 3/4, 37073 Goettingen, Germany. dr.d.brehmer@t-online.de
authors.forename: Detlef
authors.initials: D
authors.lastname: Brehmer
mesh_terms: D003876:Dermatitis, Atopic / Q000532:radiotherapy; D004311:Double-Blind Method; D006801:Humans; D007165:Immunosuppression Therapy / Q000295:instrumentation* / Q000379:methods*; D009296:Nasal Cavity; D016032:Randomized Controlled Trials as Topic; D012221:Rhinitis, Allergic, Perennial / Q000532:radiotherapy*; D006255:Rhinitis, Allergic, Seasonal / Q000532:radiotherapy*; D014466:Ultraviolet Rays; D014467:Ultraviolet Therapy / Q000295:instrumentation* / Q000379:methods*