title: [Diastolic dysfunction of left ventricle in psoriatic patients with concomitant opisthorchiasis before and after antihelminthic therapy].
abstract: The aim of the study was to evaluate left ventricular diastolic function in psoriatic patients with chronic opisthrochosis (CO) before and after antihelminthic therapy. It included 75 patients with psoriasis and CO, 50 with psoriasis alone, 50 with CO, and 20 healthy subjects. All patients underwent standard echocardiographic examination in the M-, B-, and Doppler mode. The study revealed impaired active relaxation of the left ventricle manifest as increased isovolumic relaxation time more pronounced in patients with concurrent CO and psoriasis than in those with psoriasis alone. Antihelminthic therapy did not cause deterioration of the diastolic function in these patients and should be recommended in case of combined pathology.
authors.forename: S A
authors.initials: SA
authors.lastname: Khardikova
authors.forename: E P
authors.initials: EP
authors.lastname: Berendeeva
authors.forename: V V
authors.initials: VV
authors.lastname: Kaliuzhin
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
mesh_terms: D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000627:therapeutic use*; D003971:Diastole; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D009889:Opisthorchiasis / Q000150:complications* / Q000188:drug therapy; D011379:Prognosis; D011565:Psoriasis / Q000150:complications*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000187:drug effects / Q000502:physiology*; D055815:Young Adult
chemical_list: D000871:Anthelmintics