title: Lamotrigine and absence seizures: new indication. Try valproic acid first.
abstract: In a trial including 38 children, lamotrigine, which had to be introduced very gradually in order to reduce the risk of potentially severe skin reactions, took longer than valproic acid to control typical absence seizures.
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017277:Drug Approval; D004832:Epilepsy, Absence / Q000188:drug therapy*; D005060:Europe; D006801:Humans; D000077213:Lamotrigine; D016032:Randomized Controlled Trials as Topic; D012640:Seizures / Q000188:drug therapy*; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced / Q000209:etiology; D014227:Triazines / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000927:Anticonvulsants; D014227:Triazines; D000077213:Lamotrigine