title: Small molecule induced control in duplex and triplex DNA-directed chemical reactions.
abstract: Triplex DNA binders can effectively control copper-catalysed alkyne-azide click reactions in DNA architecture, such that either duplex or triplex DNA directed reactions of terminally attached azides and alkynes occur, in the absence or presence of triplex DNA binder, respectively.
authors.affiliation: Danish Research Foundation: Centre for DNA Nanotechnology at the Interdisciplinary Nanoscience Center and the Department of Chemistry, AarhusUniversity, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors.forename: Mikkel F
authors.initials: MF
authors.lastname: Jacobsen
authors.forename: Jens B
authors.initials: JB
authors.lastname: Ravnsbaek
authors.forename: Kurt V
authors.initials: KV
authors.lastname: Gothelf
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D001483:Base Sequence; D001600:Berberine Alkaloids / Q000737:chemistry; D001665:Binding Sites; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D011804:Quinolines / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D001600:Berberine Alkaloids; D011804:Quinolines; C102232:naphthylquinoline triple-helix-binding ligand; C051802:triplex DNA; C000666:coralyne; D003300:Copper; D004247:DNA