Repairing of infarcted myocardium using a novel cell patch therapy.
A 54-year-old man underwent left anterior descending artery bypass grafting with cell patch therapy for myocardial infarction. We applied a novel approach to replicating the infarcted myocardium by anchoring polyglycolic acid felt seeded with autologous peripheral blood mononuclear cells in front of the infarcted area. The cell patch remained fixed to the myocardium for 1 month, and the infarcted myocardium was reperfused.
Yokomuro
Hiroki
H
Department of Cardiovascular Surgery, Kanagawa Cardiovascular and Respiratory Centre, Yokohama, Japan. h.yokomuro@chic.ocn.ne.jp
Ichikawa
Yukio
Y
Shiono
Noritsugu
N
Kajiwara
Hirokazu
H
D006348:Cardiac Surgical Procedures; D001026:Coronary Artery Bypass; D003331:Coronary Vessels / Q000503:physiopathology*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D009206:Myocardium / Q000473:pathology; D018919:Neovascularization, Physiologic; D011100:Polyglycolic Acid; D012038:Regeneration; D013997:Time Factors; D054457:Tissue Scaffolds; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D016896:Treatment Outcome
D011100:Polyglycolic Acid