title: Maternal floor infarction associated with oligohydramnios and cystic renal dysplasia: report of 2 cases.
abstract: Maternal floor infarction (MFI) is an unusual, idiopathic placental disorder characterized by deposition of amorphous fibrinoid material along the maternal aspect of the intervillous space. This condition is associated with poor perinatal outcome-in particular, spontaneous abortion-fetal growth restriction, and stillbirth, with a high recurrence rate in subsequent pregnancies. It is unknown whether MFI is a single entity or the common end point of different insults. Most studies have linked MFI to underlying maternal disorders including gestational hypertension, autoimmune disease, and thrombophilia. In contrast, there have been only a few case reports regarding the possibility of a fetal basis for MFI. We report 2 cases of MFI in fetuses who suffered from oligohydramnios as a result of bilateral cystic renal dysplasia. These 2 cases suggest the concept that fetoplacental factors may also play a role in MFI. It is speculated that the mechanism might involve changes in intrauterine hydrostatic pressure gradients.
authors.affiliation: Department of Pathology, Faculty of Medicine, Chulalongkorn University, 1873 King Rama IV Street, Pathumwan, Bangkok, 10330 Thailand. dr.mana4@gmail.com
authors.forename: Mana
authors.initials: M
authors.lastname: Taweevisit
authors.forename: Paul Scott
authors.initials: PS
authors.lastname: Thorner
mesh_terms: D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D006801:Humans; D007238:Infarction / Q000150:complications / Q000473:pathology*; D052177:Kidney Diseases, Cystic / Q000150:complications / Q000473:pathology*; D008297:Male; D016104:Oligohydramnios / Q000473:pathology*; D010920:Placenta / Q000098:blood supply / Q000473:pathology; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D050497:Stillbirth; D055815:Young Adult