Cytotoxicity and biocompatibility of direct and indirect pulp capping materials.
There are several studies about the cytotoxic effects of dental materials in contact with the pulp tissue, such as calcium hydroxide (CH), adhesive systems, resin composite and glass ionomer cements. The aim of this review article was to summarize and discuss the cytotoxicity and biocompatibility of materials used for protection of the dentin-pulp complex, some components of resin composites and adhesive systems when placed in direct or indirect contact with the pulp tissue. A large number of dental materials present cytotoxic effects when applied close or directly to the pulp, and the only material that seems to stimulate early pulp repair and dentin hard tissue barrier formation is CH.
Modena
Karin Cristina da Silva
KC
Department of Operative Dentistry, Endodontics and Dental Materials, University of São Paulo, Bauru, Brazil.
Casas-Apayco
Leslie Caroll
LC
Atta
Maria Teresa
MT
Costa
Carlos Alberto de Souza
CA
Hebling
Josimeri
J
Sipert
Carla Renata
CR
Navarro
Maria Fidela de Lima
MF
Santos
Carlos Ferreira
CF
D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity*; D003738:Dental Cements / Q000737:chemistry / Q000633:toxicity; D003764:Dental Materials / Q000737:chemistry / Q000633:toxicity*; D003782:Dental Pulp / Q000187:drug effects*; D003785:Dental Pulp Capping; D003804:Dentin / Q000187:drug effects; D006801:Humans
D001672:Biocompatible Materials; D003738:Dental Cements; D003764:Dental Materials