title: Descriptive profile of surgically-confirmed adult central nervous system tumors in Puerto Rico.
abstract: BACKGROUND
  Published studies regarding the incidence of central nervous system (CNS) tumors in Puerto Rico (PR) are exceedingly rare. The general understanding is that the incidence of these tumors in Puerto Rico is similar to the one found in the United States of America (USA). The objective of this study is to describe the specific profile of all the CNS tumors that are surgically intervened in Puerto Rico, through the creation of a database.
  
  
  METHODS
  A retrospective analysis of all the surgical procedures from January 1, 2002 to May 31, 2006 for adult CNS tumors in Puerto Rico was performed. Each case was evaluated for demographic information, operative procedure, lesion description and official pathological report. Recurrent lesions were excluded. The information was organized to form a database of all the CNS neoplasms.
  
  
  RESULTS
  A total of 1,018 procedures for CNS tumors were performed on 1,005 patients. The incidence rate of surgically intervened CNS tumors in Puerto Rico is 6 per 100,000 people. CNS tumors were more common in women than in men (58% vs. 42%), respectively. The mean age was 52.4 years. The most common histological type found was meningioma WHO I (24%), followed by pituitary adenomas (16%), and glioblastoma multiforme (14%).
  
  
  CONCLUSIONS
  Our results reflect a unique histopathological distribution of operated CNS tumors in Puerto Rico. In this series, primary tumors are more common than metastatic tumors. Benign histological tumors were more frequent than more malignant variants. Although this study reflects only the histologically diagnosed tumors, it is headway towards diagnosing the incidence of all CNS tumors in Puerto Rico.
authors.affiliation: Section of Neurosurgery, University of Puerto Rico, Medical Sciences Campus, PO Box 365067, San Juan, PR 00936-5067. gisela.murray@upr.edu
authors.forename: Gisela
authors.initials: G
authors.lastname: Murray
authors.forename: Lincoln
authors.initials: L
authors.lastname: Jiménez
authors.forename: Frankie
authors.initials: F
authors.lastname: Báez
authors.forename: Lilliam E
authors.initials: LE
authors.lastname: Colón-Castillo
authors.forename: Ricardo H
authors.initials: RH
authors.lastname: Brau
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011647:Puerto Rico; D012189:Retrospective Studies; D055815:Young Adult