title: Increase in prevalence of allergy-like respiratory symptoms in IDDM patients contrasting with a decrease in positive skin prick tests.
abstract: OBJECTIVE
  The goal of this study was to investigate a possible relationship between allergic symptoms, atopy skin prick test results in type 1 diabetic patients and in non diabetic controls.
  
  
  METHODS
  50 type 1 diabetic patients and 50 healthy control subjects were evaluated for allergic disorders with regard to medical history. All persons were skin-prick-tested for atopic sensitization with a common panel of inhalant and food allergens.
  
  
  RESULTS
  Although in the diabetic group 56% of the patients reported allergy-like respiratory symptoms, only 22% were found to have positive skin tests. In the control group 22% had allergic complaints and skin prick tests were positive in 34% of the cases.
  
  
  CONCLUSIONS
  Nasal and bronchial allergy-like symptoms were increased in IDDM patients in comparison to a control population. However there was a small decrease (not significant) in prevalence of positive atopy skin tests in diabetic patients in comparison to controls. This suggests that IDDM patients have an important load of allergy-like symptoms that are not linked to an IgE sensitization.
authors.affiliation: Ministry of Health Istanbul Training and Research Hospital, Istanbul.
authors.forename: Füsun
authors.initials: F
authors.lastname: Erdenen
authors.forename: Esma
authors.initials: E
authors.lastname: Altungolu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Boz
authors.forename: Serap
authors.initials: S
authors.lastname: Celik
authors.forename: Nurcan
authors.initials: N
authors.lastname: Ozbal
authors.forename: Christiane
authors.initials: C
authors.lastname: Lehners
authors.forename: François
authors.initials: F
authors.lastname: Hentges
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000453:epidemiology / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000453:epidemiology* / Q000276:immunology; D008297:Male; D015995:Prevalence; D012016:Reference Values; D012882:Skin Tests / Q000009:adverse effects*