title: The use of anaferon (pediatric formulation) for prophylaxis of acute respiratory viral infections in preschool children.
abstract: Anaferon (pediatric formulation) reduces the incidence of acute respiratory viral infections in sickly children and children with bronchial asthma and has a positive effect on the course of asthma. The preparation produces an immunomodulating effect (increases initially low IFN-gamma levels and normalizes elevated levels of IL-1beta), stimulates synthesis of IgA and IgG, exhibits cytoprotective activity, and improves local immunity of the upper airways in sickly children.
authors.affiliation: Siberian State Medical Universoty, Federal Agency for Health Care and Social Development, Tomsk.
authors.forename: E I
authors.initials: EI
authors.lastname: Kondrat'eva
authors.forename: L A
authors.initials: LA
authors.lastname: Matveeva
authors.forename: T A
authors.initials: TA
authors.lastname: Shemyakina
authors.forename: Yu I
authors.initials: YI
authors.lastname: Logvinenko
authors.forename: E V
authors.initials: EV
authors.lastname: Golikova
authors.forename: E B
authors.initials: EB
authors.lastname: Kutuzova
mesh_terms: D000906:Antibodies / Q000494:pharmacology / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007070:Immunoglobulin A / Q000097:blood / Q000378:metabolism; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism; D007371:Interferon-gamma / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D008297:Male; D012141:Respiratory Tract Infections / Q000097:blood* / Q000188:drug therapy / Q000378:metabolism / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000906:Antibodies; D000998:Antiviral Agents; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D053583:Interleukin-1beta; C547732:anaferon; D007371:Interferon-gamma