Bartonella henselae neuroretinitis in a 15-year-old girl with chronic myelogenous leukemia.
A 15-year-old girl being treated with imatinib for chronic myelogenous leukemia (CML) presented with acute vision loss in her right eye accompanied by swelling of the right side of her neck. On examination, she was found to have disk and macular edema of the right eye. Fine-needle aspiration and excisional biopsies of an enlarged submandibular lymph node were negative for malignancy. Although initial serologies were equivocal for Bartonella henselae, repeat serologies performed 1 week later upon the appearance of a macular star were positive. This is the first reported case of B. henselae in a patient with CML.
Irshad
Farhan A
FA
Tulane University School of Medicine, Department of Ophthalmology, 1413 Tulane Avenue, New Orleans, LA 70112, USA. firshad@tulane.edu
Gordon
Robert A
RA
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood; D000970:Antineoplastic Agents / Q000627:therapeutic use; D018416:Bartonella henselae / Q000276:immunology / Q000302:isolation & purification*; D001549:Benzamides; D002372:Cat-Scratch Disease / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004318:Doxycycline / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D000068877:Imatinib Mesylate; D007074:Immunoglobulin G / Q000097:blood; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000188:drug therapy; D008269:Macular Edema / Q000382:microbiology; D008279:Magnetic Resonance Imaging; D010211:Papilledema / Q000382:microbiology; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D041623:Tomography, Optical Coherence
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D000970:Antineoplastic Agents; D001549:Benzamides; D007074:Immunoglobulin G; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D004318:Doxycycline