title: Reverse geometry rigid gas permeable contact lens wear reduces high-order aberrations and the associated symptoms in post-LASIK patients.
abstract: OBJECTIVE
  This study evaluated the efficacy of custom-made reverse geometry rigid gas permeable (RGP) contact lenses in the control of symptoms related to increased wavefront aberrations after LASIK correction of myopia.
  
  
  METHODS
  Twenty-eight myopes treated with LASIK were assessed for post-LASIK symptoms (declined night vision, glare, halos and/or monocular diplopia) and corneal topography. A set of RGP contact lenses was selected as trial lenses based on the matching between the lens and the patient's corneal topography. If the fluorescein pattern between the trial lens and the corneal surface showed a central alignment, a mid-peripheral bearing and peripheral clearance and if the patient felt comfortable with the lens wear, a duplicated lens was ordered for the patient. Otherwise, a lens satisfied with corneal topography of the patient and clinical judgment was used. Visual acuity (VA) and wavefront aberrations were measured after the lens wear.
  
  
  RESULTS
  The custom-made lenses well matched the host cornea with no dislodgment in all subjects. The post-LASIK eyes showed an increase of 1 Snellen line in VA (from 0.90 +/- 0.33 to 1.11 +/- 0.24) and a significant improvement in all symptoms after the lens wear. The total higher-order aberration is significantly reduced after the lens wear with at least 70% reduction in either spherical aberration, coma, third or fourth aberration but only 33% reduction in the fifth aberration.
  
  
  CONCLUSIONS
  Reverse geometry RGP lenses with the design based on individual topographic data can improve visual performance of post-LASIK eyes by reducing higher order aberrations.
authors.affiliation: Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Tan
authors.forename: Xiaolian
authors.initials: X
authors.lastname: Chen
authors.forename: Ruo Zhong
authors.initials: RZ
authors.lastname: Xie
authors.forename: Hong
authors.initials: H
authors.lastname: He
authors.forename: Qiong
authors.initials: Q
authors.lastname: Liu
authors.forename: Yingzhuo
authors.initials: Y
authors.lastname: Guo
authors.forename: Aiping
authors.initials: A
authors.lastname: Liao
authors.forename: Xingwu
authors.initials: X
authors.lastname: Zhong
mesh_terms: D000328:Adult; D003261:Contact Lenses; D019781:Corneal Topography; D057108:Corneal Wavefront Aberration / Q000209:etiology / Q000628:therapy*; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer / Q000627:therapeutic use*; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult