Dexmedetomidine: perioperative applications in children.
Dexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.
Yuen
Vivian Man Ying
VM
Department of Anaesthesiology, Queen Mary Hospital, Pokfulam, Hong Kong, China. vtang131@hku.hk
D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000494:pharmacology; D001007:Anxiety / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D003693:Delirium / Q000517:prevention & control; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007223:Infant; D010149:Postoperative Pain / Q000517:prevention & control; D019990:Perioperative Care; D011229:Preanesthetic Medication / Q000379:methods
D000316:Adrenergic alpha-Agonists; D020927:Dexmedetomidine