Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions.
Impregnated copper on magnetite is a versatile, inexpensive and simple catalyst for the selective multicomponent reaction of terminal alkynes, aldehydes and secondary amines to give the corresponding propargylamines with excellent yields. The catalyst can be easily recovered and reused by using a simple magnet. The process could be repeated up to ten times without losing its activity.
Aliaga
María J
MJ
Instituto de Síntesis Orgánica (ISO), and Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Alicante Apdo. 99, E-03080-, Alicante, Spain.
Ramón
Diego J
DJ
Yus
Miguel
M