title: Bat-associated leptospirosis.
abstract: Leptospirosis is a globally prevalent disease that affects humans, causing systemic illness that may lead to multi-organ involvement. Clinical signs include sudden fever, general malaise, muscular pain, conjunctival suffusion, and jaundice. Disease is caused by pathogenic bacteria including over 200 serologic variants. Most serologic variants have primary reservoirs in wild mammals, which continually infect and colonize domesticated animals. The organism has been recovered from rats, swine, dogs, cattle, and other animals, notably bats. Most studies have focused on domestic animals as reservoir hosts; however, because of their abundance, spatial distribution, and interrelationship with domestic animals, bats are becoming an epidemiologically significant source of leptospires. We present a case of serologically confirmed leptospirosis after bat exposure to add to the growing literature of bats as a possible source of transmission. Recognition of the common presentation of leptospirosis and Weil's disease, and identification of animal vectors, including bats, allows for the selection of appropriate antibiotic management to aid in resolution of symptomotology.
authors.affiliation: Department of Medicine, Northwestern University Feinberg School of Medicine, 251 E Huron St, Galter 3-150, Chicago, IL 60611, USA.
authors.forename: Neelam A
authors.initials: NA
authors.lastname: Vashi
authors.forename: Pavani
authors.initials: P
authors.lastname: Reddy
authors.forename: Diane B
authors.initials: DB
authors.lastname: Wayne
authors.forename: Bradley
authors.initials: B
authors.lastname: Sabin
mesh_terms: D000818:Animals; D002685:Chiroptera; D006801:Humans; D007919:Leptospira; D007922:Leptospirosis / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D014895:Weil Disease / Q000175:diagnosis* / Q000628:therapy / Q000635:transmission*