title: A follow-up of integrated positron emission tomography/computed tomography after curative resection of non-small-cell lung cancer in asymptomatic patients.
abstract: OBJECTIVE
  A follow-up integrated positron emission tomography/computed tomography (PET/CT), as part of a more intensive surveillance program, has been performed at around 1 year after curative resection, regardless of the patients' symptoms or findings in other tests. This study was designed to evaluate the results of this follow-up integrated PET/CT in patients treated for non-small-cell lung cancer without symptoms or abnormal findings.
  
  
  METHODS
  Between January 2003 and December 2006, this study enrolled 86 patients with non-small cell lung cancer who had no clinical or radiologic evidence of recurrence after curative resection before integrated PET/CT and underwent a follow-up integrated PET/CT around 1 year at our institution.
  
  
  RESULTS
  The time from operation to the follow-up integrated PET/CT check was 13.4 +/- 4.4 months. Integrated PET/CT showed negative findings in 41 (47.7%) patients, equivocal findings in 16 (18.6%) patients, and positive findings in 29 (33.7%) patients. Twenty-seven (31.4%) patients had recurrent disease and 2 patients had extrathoracic double primary cancer. Six patients had extrathoracic recurrence without intrathoracic recurrence.
  
  
  CONCLUSIONS
  A postoperative follow-up integrated PET/CT can be used for early detection of recurrence in asymptomatic patients who had had resection of non-small-cell lung cancer. Further studies are required to evaluate the cost-effectiveness or survival benefit of follow-up integrated PET/CT.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Kyungpook National University, College of Medicine, Daegu 700-721, Korea. skcho@knu.ac.kr
authors.forename: Sukki
authors.initials: S
authors.lastname: Cho
authors.forename: Eung Bae
authors.initials: EB
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed