Flexible synthesis, structural determination, and synthetic application of a new C1-symmetric chiral ammonium betaine.
A C(1)-symmetric chiral ammonium betaine has been developed, and its intramolecular ion-pairing structure in solid state and its catalytic performance to achieve the highly stereoselective Mannich-type reaction of 2-alkoxythiazol-5(4H)-ones are revealed.
Uraguchi
Daisuke
D
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho B2-3(611), Chikusa, Nagoya 464-8603, Japan.
Koshimoto
Kyohei
K
Ooi
Takashi
T
D001622:Betaine / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D008352:Mannich Bases / Q000737:chemistry; D008968:Molecular Conformation; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D008352:Mannich Bases; D000644:Quaternary Ammonium Compounds; D001622:Betaine