title: Risk factors for healthcare-associated infection in pediatric intensive care units: a systematic review.
abstract: A systematic review of observational studies on risk factors for healthcare-associated infection in pediatric Intensive Care Units (ICU) was carried out. Studies indexed in MEDLINE, LILACS, Cochrane, BDENF, CAPES databases published in English, French, Spanish or Portuguese between 1987 and 2006 were included and cross references added. Key words for search were 'cross infection' and 'Pediatric Intensive Care Units' with others sub-terms included. 11 studies were selected from 419 originally found: four studies had healthcare-associated infection as the main outcome without a specific site; three articles identified factors associated with lower respiratory tract infection (pneumonia or tracheitis); three articles were concerned with laboratory-confirmed bloodstream infection; and a single retrospective study analyzed urinary tract infection. The production of evidence on risk factors Paediatric ICU has not kept up the same pace of that on adult - there are few studies with adequate design and statistical analysis. The methodological diversity of the studies did not allow for a summarized measurement of risk factors.
authors.affiliation: Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brasil. jcorreiajmello@gmail.com
authors.forename: Maria Júlia Gonçalves de
authors.initials: MJ
authors.lastname: Mello
authors.forename: Maria de Fátima Pessoa Militão de
authors.initials: Mde F
authors.lastname: Albuquerque
authors.forename: Heloísa Ramos
authors.initials: HR
authors.lastname: Lacerda
authors.forename: Wayner Vieira de
authors.initials: WV
authors.lastname: Souza
authors.forename: Jailson B
authors.initials: JB
authors.lastname: Correia
authors.forename: Murilo Carlos Amorim de
authors.initials: MC
authors.lastname: Britto
mesh_terms: D002648:Child; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D003695:Delivery of Health Care; D006801:Humans; D015278:Intensive Care Units, Pediatric; D012141:Respiratory Tract Infections / Q000517:prevention & control; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000517:prevention & control