title: Rhodium-catalyzed asymmetric addition of arylboronic acids to beta-phthaliminoacrylate esters toward the synthesis of beta-amino acids.
abstract: Rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to beta-phthaliminoacrylate esters took place efficiently to give high yields of beta-aryl-beta-amino acid esters with 96-99% enantioselectivity, which was realized by use of a hydroxorhodium/chiral diene complex.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nishimura
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Makoto
authors.initials: M
authors.lastname: Nagaosa
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Okamoto
authors.forename: Ryo
authors.initials: R
authors.lastname: Shintani
authors.forename: Fuk-yee
authors.initials: FY
authors.lastname: Kwong
authors.forename: Wing-yiu
authors.initials: WY
authors.lastname: Yu
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010795:Phthalic Acids / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000179:Acrylates; D000596:Amino Acids; D001897:Boronic Acids; D009942:Organometallic Compounds; D010795:Phthalic Acids; C547805:beta-phthaliminoacrylate ester; D012238:Rhodium