title: Defunctioning stoma in high ASA grade, aged patients, with bowel occlusion due to advanced cancer: is it still worthwhile?
abstract: OBJECTIVE
  The aim of this study was to assess the role of defunctioning stoma (DS) in elderly high-risk patients with bowel obstruction from advanced colorectal cancer, by exploring consistent variables of outcome, because every other procedure was unfeasible.
  
  
  METHODS
  A 6-year survey in a single surgery unit (between 1999 and 2004) was retrospectively evaluated, allowing to collect a cohort of 75 patients, aged over 65, who overall presented such critical condition. Pre-operatively, American Society of Anaesthesiologist grade classification was used. Post-operative course was monitored by focusing on gauging symptom relief. So, a validated assessment scale was employed to evaluate physical distress symptoms, graduated on a Likert scale and compared at baseline and day 7, on days 7 and 30, post-operatively. Length of hospital stay (LHS), morbidity, in-hospital (within 30 days) and overall mortality (within 6 months) were also assessed. Paired t test was used as statistical analysis to ascertain improvement of symptoms.
  
  
  RESULTS
  All symptoms improved significantly (range, p < 0.05 to p < 0.01) within the surveyed time, with exception of vomiting on day 30 (p = 0.14). Average LHS was 22.8 (standard deviation, +/-3.856) days. Overall morbidity was detected in 68 (91%) patients. In-hospital and overall mortality rates accounted for 27 (35.8%) patients and for 48 (100%) patients, respectively.
  
  
  CONCLUSIONS
  The role of DS was effective to improve symptom relief but was poor in terms of morbidity and mortality control. So, ethical concerns have to be addressed, and medical treatment or stenting for left-side obstructions only should be considered as alternative procedures.
authors.affiliation: Department of Surgery and Orthopaedics, Azienda Ospedaliera C Poma Mantua, Piazza 80th Fanteria 1, 46041 Asola, MN, Italy. corrado.asteria@libero.it
authors.forename: Corrado R
authors.initials: CR
authors.lastname: Asteria
authors.forename: Gabriella
authors.initials: G
authors.lastname: Nesi
authors.forename: Chiara
authors.initials: C
authors.lastname: Minari
authors.forename: Paolo
authors.initials: P
authors.lastname: Viganò
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D003625:Data Collection; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery*; D007902:Length of Stay; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D054047:Surgical Stomas; D016896:Treatment Outcome