title: [Measurement of ventricular twist by 2D speckle tracking early after acute myocardial infarction. Comparison between anterior and inferior infarction].
abstract: BACKGROUND
  Left Ventricular twist (LV twist) is defined as the apical counter-clockwise rotation relative to the clockwise basal rotation. It has been shown that LV twist decreases after myocardial infarction (MI) and that it is well correlated with left ventricular ejection fraction. Most studies have only evaluated anterior wall MI. The aim of our study was to determine whether LV twist is dependent on the infarct territory (anterior vs. inferior) and whether there is a correlation between LV twist and matrix metalloproteinase-9, a marker of LV remodeling.
  
  
  METHODS
  We measured LV twist using echocardiography with 2D speckle tracking in patients with acute MI and in a control group.
  
  
  RESULTS
  We evaluated 27 controls and 35 patients with acute MI, 15 with anterior wall and 20 with inferior wall MI. LV twist was significantly decreased after MI, compared to the control group (10.93 +/- 2.05 vs 15.5 +/- 2.29; p = 0.003). There was no difference between anterior and inferior MI. LV rotation was decreased in the infarct area. We did not observe a correlation between LV twist and MMP-9, or creatine phosphokinase.
  
  
  CONCLUSIONS
  With this study we confirm that LV twist decreases after acute MI. Moreover, we show that LV apical rotation is mostly decreased after large anterior MI. As apical rotation is important for ejection and aspiration (untwisting), this could be a possible mechanism of LV dysfunction after MI.
authors.affiliation: Centre Hospitalier d e Luxembourg, Luxembourg, Luxembourg.
authors.forename: C
authors.initials: C
authors.lastname: Blasen
authors.forename: A
authors.initials: A
authors.lastname: Codreanu
authors.forename: F
authors.initials: F
authors.lastname: Robert
authors.forename: N
authors.initials: N
authors.lastname: Meniconi
authors.forename: J
authors.initials: J
authors.lastname: Beissel
authors.forename: D R
authors.initials: DR
authors.lastname: Wagner
mesh_terms: D000328:Adult; D056988:Anterior Wall Myocardial Infarction / Q000503:physiopathology; D004452:Echocardiography; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D056989:Inferior Wall Myocardial Infarction / Q000503:physiopathology; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000503:physiopathology; D012016:Reference Values; D012399:Rotation; D018487:Ventricular Dysfunction, Left / Q000209:etiology