title: [Mediastinal germ cell tumor with somatic-type malignancy successfully treated with chemotherapy followed by surgical resection combined with lobectomy: report of a case].
abstract: A 28-year-old male visited our hospital with complaint of chest pain. Clinical examination revealed a huge mediastinal mass which was diagnosed as non-seminomatous germ cell tumor. The patient underwent 5 cycles of chemotherapy (bleomycin, etoposide, and cisplatin) followed by resection of the tumor combined with left upper lobectomy. Final pathological diagnosis was germ cell tumor with somatic-type malignancy. While the prognosis of mediastinal germ cell tumor with somatic-type malignancy is known to be extremely poor, multimodality at an early stage is the key to successful treatment.
authors.affiliation: Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kaseda
authors.forename: H
authors.initials: H
authors.lastname: Horio
authors.forename: T
authors.initials: T
authors.lastname: Hijima
authors.forename: T
authors.initials: T
authors.lastname: Hatou
authors.forename: M
authors.initials: M
authors.lastname: Harada
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000628:therapy*; D009373:Neoplasms, Germ Cell and Embryonal / Q000628:therapy*; D011013:Pneumonectomy