[Experience from surgical resection for 48 cases of hilar cholangiocarcinoma].
OBJECTIVE
To summarize the methods, safety and efficiency of surgical resection for hilar cholangiocarcinoma.


METHODS
The clinical and follow-up data of 48 patients with hilar cholangiocarcinoma underwent surgical resection from January 2003 to December 2007 were analyzed retrospectively. There were 26 male and 22 female, aged from 38 to 72 years old with a mean of 63.6 years old.


RESULTS
Perioperative management including percutaneous transhepatic biliary drainage applied in 19 cases and portal vein embolization applied in 2 cases. Eight patients were treated with extrahepatic bile duct resection with or without parital hepatic segment II resection, 10 cases with perihilar hepatic resection (segment IVB, partial V, partial VIII, I), 28 cases with extended hemihepatectomy and 2 cases with central hepatic resection (segment IVB, V, VIII, I). R0 resection rate was 89.5% and the operative mortality was 2.1%. The 1-, 3- and 5-year survival rate were 93.5%, 51.8% and 36.5%, respectively. Patients undergoing extended hepatic resection survived significantly longer than those undergoing partial hepatic resection (P = 0.034).


CONCLUSIONS
Extended hepatic resection for hilar cholangiocarcinoma offers good outcomes with an acceptable mortality rate.
Cai
Shou-wang
SW
Department of Hepatobiliary Surgery, General Hospital of People's Liberation Army, Beijing 100853, China. caisw8077.cai@vip.sina.com
Duan
Wei-dong
WD
Liu
Zhe
Z
Zhao
Xiang-qian
XQ
Zhang
Wen-zhi
WZ
Wang
Jing
J
Huang
Xiao-qiang
XQ
Dong
Jia-hong
JH
Huang
Zhi-qiang
ZQ
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome