title: Genetic diversity of the S10 RNA segment of field and vaccine strains of bluetongue virus from the P. R. China.
abstract: Bluetongue virus (BTV) infection of ruminants is endemic throughout tropical and subtropical regions of the world. However, the molecular epidemiology of BTV infection in China has not yet been reported. In this study, the S10 gene segments from 30 BTV isolates, one attenuated BTV strain, one vaccine BTV strain, and one South Africa BTV prototype strain, were sequenced. Phylogenetic analysis of the S10 genes showed that Chinese BTV isolates could be classified into two phyletic subgroups, and the clustering of Chinese BTV viruses was dependent on their geographical origin and the number of generations for which they had been propagated, rather than their host species or year of isolation.
authors.affiliation: College of Animal Science and Technology, Yunnan Agricultural University, 650201 Kunming, China. dxg111@gmail.com
authors.forename: Yifang
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Du
authors.forename: Wengui
authors.initials: W
authors.lastname: Li
authors.forename: Jinyao
authors.initials: J
authors.lastname: Li
authors.forename: Jianping
authors.initials: J
authors.lastname: Liu
authors.forename: Jianbo
authors.initials: J
authors.lastname: Zhu
authors.forename: Nianzu
authors.initials: N
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001819:Bluetongue / Q000821:virology*; D001820:Bluetongue virus / Q000235:genetics* / Q000302:isolation & purification; D002681:China; D016000:Cluster Analysis; D014644:Genetic Variation; D005838:Genotype; D017720:Molecular Epidemiology; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D012418:Ruminants / Q000821:virology*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
chemical_list: D012367:RNA, Viral