Switching on epigenetic therapy.
Reversible epigenetic changes that alter gene expression are a characteristic of many cancers and other diseases. Biotech companies are taking note and are starting to develop new drugs to reverse such pathogenic "epimutations."
Karberg
Sascha
S
D042002:Chromatin Assembly and Disassembly / Q000187:drug effects*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D005786:Gene Expression Regulation; D056572:Histone Deacetylase Inhibitors / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
D056572:Histone Deacetylase Inhibitors