title: Study of antimycotic activity of lyticase.
abstract: Laboratory studies of lyticase (enzymatic drug) as an antimycotic agent were carried out. The enzyme reduced optical density of Candida albicans test culture, inhibited adhesion of yeast-like fungi on vaginal epitheliocytes, stimulated the formation of germinative tubes, and made Candida albicans more available for phagocytosis.
authors.affiliation: Department of Microbiology and Virology, Russian University of Peoples' Friendship, Moscow, Russia.
authors.forename: N P
authors.initials: NP
authors.lastname: Sachivkina
authors.forename: E G
authors.initials: EG
authors.lastname: Kravtsov
authors.forename: E A
authors.initials: EA
authors.lastname: Vasilyeva
authors.forename: I V
authors.initials: IV
authors.lastname: Anokhina
authors.forename: M V
authors.initials: MV
authors.lastname: Dalin
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects* / Q000502:physiology; D002177:Candidiasis / Q000188:drug therapy; D002478:Cells, Cultured; D004847:Epithelial Cells / Q000382:microbiology; D005260:Female; D004693:Glucan Endo-1,3-beta-D-Glucosidase / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D051379:Mice; D009097:Multienzyme Complexes / Q000494:pharmacology* / Q000627:therapeutic use; D010447:Peptide Hydrolases / Q000494:pharmacology* / Q000627:therapeutic use; D010587:Phagocytosis; D014621:Vagina / Q000166:cytology
chemical_list: D000935:Antifungal Agents; D009097:Multienzyme Complexes; C025310:lyticase; D004693:Glucan Endo-1,3-beta-D-Glucosidase; D010447:Peptide Hydrolases