title: The effect of maternal body mass index on neonatal outcome in women receiving a single course of antenatal corticosteroids.
abstract: OBJECTIVE
  The aim of this study was to determine the effect of maternal body mass index on the incidence of neonatal prematurity morbidities in those who receive corticosteroids.
  
  
  METHODS
  This was a secondary analysis of a trial of corticosteroids in women at risk for preterm birth. Women receiving a single course of corticosteroids were classified by their prepregnancy body mass index (<25 and > or = 25) and compared on a composite outcome comprised of several neonatal morbidities and on each individual outcome.
  
  
  RESULTS
  Of 183 eligible women, 96 (52.5%) had a body mass index of <25 and 87 (47.5%) had a body mass index of > or = 25. The composite outcome occurred more frequently in the body mass index of > or = 2 5 group (28.7%), compared with those with a body mass index of <25 (18.8%), although this was not statistically significant (odds ratio, 1.75; 95% confidence interval, 0.83-3.72). Body mass index was not associated with outcomes after adjusting for confounding.
  
  
  CONCLUSIONS
  Maternal body mass index did not affect neonatal prematurity morbidities in those receiving corticosteroids.
authors.affiliation: Department of Obstetrics, Oregon Health & Science University, Portland, OR, USA. hashimaj@ohsu.edu
authors.forename: Jason N
authors.initials: JN
authors.lastname: Hashima
authors.forename: Yinglei
authors.initials: Y
authors.lastname: Lai
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Wapner
authors.forename: Yoram
authors.initials: Y
authors.lastname: Sorokin
authors.forename: Donald J
authors.initials: DJ
authors.lastname: Dudley
authors.forename: Alan
authors.initials: A
authors.lastname: Peaceman
authors.forename: Catherine Y
authors.initials: CY
authors.lastname: Spong
authors.forename: Jay D
authors.initials: JD
authors.lastname: Iams
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Leveno
authors.forename: Margaret
authors.initials: M
authors.lastname: Harper
authors.forename: Steve N
authors.initials: SN
authors.lastname: Caritis
authors.forename: Michael
authors.initials: M
authors.lastname: Varner
authors.forename: Menachem
authors.initials: M
authors.lastname: Miodovnik
authors.forename: Brian M
authors.initials: BM
authors.lastname: Mercer
authors.forename: John M
authors.initials: JM
authors.lastname: Thorp
authors.forename: Mary J
authors.initials: MJ
authors.lastname: O'Sullivan
authors.forename: Susan M
authors.initials: SM
authors.lastname: Ramin
authors.forename: Marshall
authors.initials: M
authors.lastname: Carpenter
authors.forename: Dwight J
authors.initials: DJ
authors.lastname: Rouse
authors.forename: Baha
authors.initials: B
authors.lastname: Sibai
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use; D015992:Body Mass Index; D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology / Q000517:prevention & control; D003907:Dexamethasone / Q000627:therapeutic use; D020345:Enterocolitis, Necrotizing / Q000453:epidemiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology* / Q000517:prevention & control*; D007273:Injections, Intramuscular; D020300:Intracranial Hemorrhages / Q000453:epidemiology / Q000517:prevention & control; D007969:Leukomalacia, Periventricular / Q000453:epidemiology / Q000517:prevention & control; D009765:Obesity / Q000453:epidemiology; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000453:epidemiology / Q000517:prevention & control; D012178:Retinopathy of Prematurity / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000305:Adrenal Cortex Hormones; D003907:Dexamethasone; D001623:Betamethasone