title: Complementary and alternative medicine use, spending, and quality of life in early stage breast cancer.
abstract: BACKGROUND
  Up to 80% of women with breast cancer use complementary and alternative medicine (CAM) therapies to improve quality of life (QOL) during treatment.
  
  
  OBJECTIVE
  The objective of this study was to explore the association between CAM therapy use, spending on CAM therapies, demographic variables, surgical treatment, and QOL.
  
  
  METHODS
  A secondary analysis was conducted for women with early stage breast cancer (N = 222) who were enrolled in a nursing intervention study after breast surgery. The complementary therapy utilization instrument included specific CAM therapies used, number of treatments, and spending. The number of major categories of CAM and the specific CAM therapies used were analyzed in relation to study variables using proportional odds logistic regression models. The outcome of spending for major CAM categories was analyzed using linear mixed effects modeling.
  
  
  RESULTS
  A majority of women (56.8%) used at least one CAM therapy, and the biologically based therapies category was most frequently used (43.7%). Women with less than a college level of education were less likely to use CAM (odds ratio [OR] = 0.36, 95% confidence interval [CI] = 0.15-0.86, p < .01). Women who were employed were more likely to use therapies from multiple CAM categories (OR = 2.42, 95% CI = 1.00-5.88, p < .05), and those with lower QOL were more likely to use CAM (OR = 0.97, 95% CI = 0.95-0.99, p < .01). The results support that women with early stage breast cancer, especially those with lower QOL, are highly likely to use CAM therapies. Further research is needed on CAM interventions to enhance supportive care for breast cancer.
authors.affiliation: College of Nursing, Michigan State University, East Lansing, MI 48824, USA. gwyatt@msu.edu
authors.forename: Gwen
authors.initials: G
authors.lastname: Wyatt
authors.forename: Alla
authors.initials: A
authors.lastname: Sikorskii
authors.forename: Celia E
authors.initials: CE
authors.lastname: Wills
authors.forename: Hong
authors.initials: H
authors.lastname: Su
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000191:economics / Q000523:psychology* / Q000628:therapy*; D000529:Complementary Therapies / Q000191:economics* / Q000379:methods / Q000706:statistics & numerical data*; D016001:Confidence Intervals; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007389:Internal-External Control; D008875:Middle Aged; D016017:Odds Ratio; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D017060:Patient Satisfaction / Q000191:economics / Q000706:statistics & numerical data*; D011788:Quality of Life / Q000523:psychology*; D012648:Self Care / Q000706:statistics & numerical data; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D016387:Women's Health / Q000191:economics; D055815:Young Adult