title: Nutritional secondary hyperparathyroidism in two cats: evaluation of bone mineral density with dual-energy X-ray absorptiometry and computed tomography.
abstract: Two three-month-old, intact female Abyssinian cats were presented with a history of lameness, constipation and ataxia. The cats had been fed a diet composed almost exclusively of meat. Both showed severe osteopenia and multiple pathological fractures on radiography. Following euthanasia of the more severely affected cat, postmortem examination revealed changes consistent with nutritional secondary hyperparathyroidism and fibrous osteodystrophy, such as cortical thinning, massive connective tissue invasion in the diaphysis of long bones, and hypertrophy of the chief cells in both parathyroid glands. After introducing a balanced commercial diet to the surviving cat, bone mineralisation improved from the baseline value, and at subsequent examinations at three, six and 22 weeks later, as indicated by bone mineral density measurements obtained by dual-energy X-ray absorptiometry and computed tomography.
authors.affiliation: Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark. Maria.Dimopoulou@uds.slu.se
authors.forename: M
authors.initials: M
authors.lastname: Dimopoulou
authors.forename: J
authors.initials: J
authors.lastname: Kirpensteijn
authors.forename: D H
authors.initials: DH
authors.lastname: Nielsen
authors.forename: L
authors.initials: L
authors.lastname: Buelund
authors.forename: M S
authors.initials: MS
authors.lastname: Hansen
mesh_terms: D015502:Absorptiometry, Photon / Q000662:veterinary; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging / Q000662:veterinary; D002415:Cats; D017809:Fatal Outcome; D001068:Feeding and Eating Disorders / Q000209:etiology / Q000662:veterinary; D005260:Female; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D007794:Lameness, Animal / Q000000981:diagnostic imaging / Q000209:etiology; D000077239:Meloxicam; D013843:Thiazines / Q000627:therapeutic use; D013844:Thiazoles / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000662:veterinary; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013843:Thiazines; D013844:Thiazoles; D000077239:Meloxicam