title: Comparison of Histopathological Alterations Due to Sublethal CCl(4) on Rosy Barb (Puntius conchonius) and Amphioxus (Branchiostoma belcheri) with Implications of Liver Ontogeny.
abstract: ABSTRACT This study was undertaken to examine the histopathological effects of CCl(4) on rosy barbs and amphioxus with an aim to compare the homology between rosy barb liver and amphioxus digestive caecum. It was found that the 96 h LC(50) values were 23.9 +/- 4 mg/L and 18.9 +/- 2 mg/L for rosy barbs and amphioxus, respectively. Histological examinations showed that exposure to sublethal CCl(4) caused damage to the liver, kidney, and gill in rosy barb, and to the digestive caecum and gill in amphioxus. It is clear that both rosy barb liver and amphioxus digestive caecum were the prominent target organs of CCl(4), suggesting that the digestive caecum in amphioxus is homologous to the liver in rosy barb at least in respect to toxic damages of CCl(4).
authors.affiliation: Department of Marine Biology, Ocean University of China, Qingdao, PR China.
authors.forename: H
authors.initials: H
authors.lastname: Bhattacharya
authors.forename: S
authors.initials: S
authors.lastname: Zhang
authors.forename: Q
authors.initials: Q
authors.lastname: Xiao