Effects of extracellular calcium on the volley activity of entorhinal cortex neurons in neonatal rats: computer simulation.
The calcium-dependent volley activity of neurons in the entorhinal cortex of neonatal rats increased when the extracellular Ca(2+) concentration decreased from 2 to 1 mM. This may be associated with changes in the properties of the slow sodium current. Computer simulation of volley neurons using a model including a relationship between the slow sodium current and extracellular Ca(2+) supported this suggestion.
Sheroziya
M G
MG
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia. sherozia@yandex.ru
Egorov
A V
AV
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn; D002118:Calcium / Q000378:metabolism*; D003198:Computer Simulation; D018728:Entorhinal Cortex / Q000502:physiology*; D005110:Extracellular Space / Q000378:metabolism*; D008564:Membrane Potentials / Q000502:physiology; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D051381:Rats; D012964:Sodium / Q000378:metabolism
D012964:Sodium; D002118:Calcium