title: Superficial siderosis of the central nervous system manifested with seizures.
abstract: Superficial siderosis of the central nervous system (CNS) is caused by repeated hemorrhage into the subarachnoid space with resultant hemosiderin deposition in the subpial layers of the brain and spinal cord. Progressive ataxia and hearing impairment are the most common manifestations of the disorder. We describe a male patient admitted to our hospital for recurrent seizures over the past 3 months. He was diagnosed eventually as having superficial siderosis of the CNS through brain MRI; however, he presented with only mild hearing impairment without any cerebellar deficits. Seizures can be the major presentation of the superficial siderosis.
authors.affiliation: Department of Neurology, The First Affiliated Hospital, School of Medicine, Zhejiang University, ZheJiang Province 310003, China.
authors.forename: Kang
authors.initials: K
authors.lastname: Wang
authors.forename: Ziqi
authors.initials: Z
authors.lastname: Xu
authors.forename: Ge
authors.initials: G
authors.lastname: Xiong
authors.forename: Luo
authors.initials: L
authors.lastname: Benyan
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D002490:Central Nervous System / Q000473:pathology* / Q000503:physiopathology; D002524:Cerebellar Ataxia / Q000209:etiology / Q000503:physiopathology; D002531:Cerebellum / Q000473:pathology / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008636:Mesencephalon / Q000473:pathology / Q000503:physiopathology; D012640:Seizures / Q000209:etiology* / Q000503:physiopathology; D012806:Siderosis / Q000150:complications* / Q000503:physiopathology; D013345:Subarachnoid Hemorrhage / Q000150:complications; D013346:Subarachnoid Space / Q000473:pathology / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine