title: 2009 H1N1 influenza.
abstract: Within 2 months of its discovery last spring, a novel influenza A (H1N1) virus, currently referred to as 2009 H1N1, caused the first influenza pandemic in decades. The virus has caused disproportionate disease among young people with early reports of virulence similar to that of seasonal influenza. This clinical review provides an update encompassing the virology, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of the 2009 H1N1 virus. Because information about this virus, its prevention, and treatment are rapidly evolving, readers are advised to seek additional information. We performed a literature search of PubMed using the following keywords: H1N1, influenza, vaccine, pregnancy, children, treatment, epidemiology, and review. Studies were selected for inclusion in this review on the basis of their relevance. Recent studies and articles were preferred.
authors.affiliation: Mayo Vaccine Research Group, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
authors.forename: Seth J
authors.initials: SJ
authors.lastname: Sullivan
authors.forename: Robert M
authors.initials: RM
authors.lastname: Jacobson
authors.forename: Walter R
authors.initials: WR
authors.lastname: Dowdle
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Poland
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines / Q000627:therapeutic use; D007251:Influenza, Human / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy / Q000821:virology; D011247:Pregnancy
chemical_list: D000998:Antiviral Agents; D007252:Influenza Vaccines