Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report.
BACKGROUND
Patients with migraine headaches are frequently prescribed topiramate to treat their condition.


METHODS
We present a case of bilateral acute angle-closure glaucoma occurring 2 days after topiramate therapy was increased for symptoms related to migraine.


CONCLUSIONS
Acute angle-closure glaucoma secondary to topiramate is an uncommon but serious adverse reaction that may result in severe morbidity such as permanent visual loss if not recognized in a timely manner. Treatment differs from primary acute angle-closure glaucoma in that discontinuation of topiramate is necessary for the glaucoma to resolve.
Cole
Kendra L
KL
Department of Emergency Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Wang
Ernest E
EE
Aronwald
Richard M
RM
D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose