Evaluation of the hemodynamic impact of continuous renal replacement therapy in healthy dogs.
We performed continuous renal replacement therapy (CRRT) on clinically healthy dogs to evaluate the effects of CRRT on hemodynamics. Heart rate, arterial blood pressure, and central venous pressure of the dogs (n=6) were recorded during the procedure, which was performed under general anesthesia. Throughout the CRRT, heart rate and arterial blood pressure were stable. Central venous pressure increased after CRRT termination but returned to the basal level within 30 min. In this study, hemodynamic alterations, including hypotension, hypertension, and arrhythmias, were not observed during CRRT. These observations suggest that the CRRT protocol used in the present study can be safely applied to clinical cases with acute renal failure.
Shimokawa Miyama
Takako
T
Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University.
Itamoto
Kazuhito
K
Yoshioka
Chihiro
C
Minami
Koji
K
Okawa
Takumi
T
Fujisaki
Yuka
Y
Hiraoka
Hiroko
H
Mizuno
Takuya
T
Okuda
Masaru
M
D000768:Anesthesia, General / Q000662:veterinary; D000818:Animals; D001794:Blood Pressure; D002496:Central Venous Pressure; D003971:Diastole; D004285:Dogs; D005260:Female; D006339:Heart Rate; D017583:Hemodiafiltration / Q000379:methods / Q000662:veterinary*; D006439:Hemodynamics / Q000502:physiology*; D012016:Reference Values; D017582:Renal Replacement Therapy / Q000379:methods / Q000662:veterinary*; D013599:Systole