title: Pupil size, white-to-white corneal diameter, and anterior chamber depth in patients with myopia.
abstract: OBJECTIVE
  To evaluate anatomical parameters in a population of patients with myopia.
  
  
  METHODS
  Nine hundred sixty-four myopic eyes (-3.00 to -20.00 diopters [D] spherical equivalent refraction) were evaluated to measure mesopic and photopic pupil size with an infrared pupillometer; anterior chamber depth and white-to-white corneal diameter were obtained with Orbscan II (Bausch & Lomb). Correlation analysis was performed to evaluate the relationships among anatomical parameters of the anterior segment of the eye.
  
  
  RESULTS
  Average change in pupil size between mesopic and photopic conditions shows a uniform gap of 1.5 mm in patients aged 18 to 62 years with a slight insignificant trend to decrease with age. Photopic and mesopic pupil size were highly correlated (r=0.694, P<.001) and the difference between both measures was positively correlated with mesopic pupil size (r=0.207, P<.001) and inversely correlated with photopic pupil size (r=0.561, P<.001). Anterior chamber depth and white-to-white corneal diameter were positively correlated (r=0.389, P<.001). White-to-white corneal diameter and anterior chamber depth were not correlated with age (r=-0.096, P<.001) or anterior chamber depth (r=-0.183, P<.001-0.183) as a function of age.
  
  
  CONCLUSIONS
  Average difference between photopic and mesopic pupil size remained constant across the range of ages included in this cohort. A positive correlation was noted between anterior segment dimensions, and anterior chamber depth decreased with age.
authors.affiliation: Fernandez-Vega Ophthalmological Institute, Oviedo, Spain. j.alfonso@fernandez-vega.com
authors.forename: José F
authors.initials: JF
authors.lastname: Alfonso
authors.forename: Teresa
authors.initials: T
authors.lastname: Ferrer-Blasco
authors.forename: José M
authors.initials: JM
authors.lastname: González-Méijome
authors.forename: M
authors.initials: M
authors.lastname: García-Manjarres
authors.forename: Sofia C
authors.initials: SC
authors.lastname: Peixoto-de-Matos
authors.forename: Robert
authors.initials: R
authors.lastname: Montés-Micó
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D000867:Anterior Chamber / Q000473:pathology*; D001837:Body Weights and Measures; D055253:Color Vision / Q000502:physiology; D003315:Cornea / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D055255:Mesopic Vision / Q000502:physiology; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology*; D055815:Young Adult