title: Massive pulmonary embolism in children.
abstract: We present 3 children with massive pulmonary embolism and review 17 recent pediatric reports. Malignancies were a frequent cause (40%), and sudden death was common (60%). Compared with adults, diagnosis was more likely to be made at autopsy (P < .0001), more children were treated with embolectomy/thrombectomy (P = .0006), and mortality was greater (P = .03).
authors.affiliation: Department of Pediatrics, Division of Critical Care, Columbia University, College of Physicians and Surgeons, Children's Hospital of New York-Presbyterian, New York, NY 10032, USA. jsb106@columbia.edu
authors.forename: J Scott
authors.initials: JS
authors.lastname: Baird
authors.forename: James S
authors.initials: JS
authors.lastname: Killinger
authors.forename: Kathy J
authors.initials: KJ
authors.lastname: Kalkbrenner
authors.forename: Michael R
authors.initials: MR
authors.lastname: Bye
authors.forename: Charles L
authors.initials: CL
authors.lastname: Schleien
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006450:Hemoglobin SC Disease / Q000150:complications; D006486:Hemosiderosis / Q000150:complications; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000150:complications; D008297:Male; D011655:Pulmonary Embolism / Q000150:complications* / Q000175:diagnosis / Q000628:therapy