title: [Pulmonary embolism as a first manifestation of synchronous occurrence of two neoplasms].
abstract: A case of 67-year-old man with a first episode of acute, unprovoked venous thromboembolism (VTE). Screening for cancer revealed coexistence of two neoplasms: colon sigmoid cancer (operated on 6 weeks after pulmonary embolism onset), and multiple myeloma (treated successfully with thalidomide and dexamethasone). Low molecular weight heparin use as VTE treatment was followed by thromboprophylaxis for myeloma therapy. During a 30-month follow-up period, neither new thromboembolic complications nor cancer recurrence were observed. Overlapping different prothrombotic mechanisms of double malignancy might result in detection of both neoplasms at early stage.
authors.affiliation: Oddział Chorób Wewnetrznych, Szpital im. J. Strusia, Poznań. welikowski@wp.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Elikowski
authors.forename: Maria
authors.initials: M
authors.lastname: Lewandowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Małek
authors.forename: Piotr
authors.initials: P
authors.lastname: Krokowicz
authors.forename: Grazyna
authors.initials: G
authors.lastname: Piotrowska-Stelmaszyk
authors.forename: Krystyna
authors.initials: K
authors.lastname: Zawilska
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003110:Colonic Neoplasms / Q000150:complications* / Q000175:diagnosis*; D003907:Dexamethasone / Q000627:therapeutic use; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D016609:Neoplasms, Second Primary / Q000150:complications* / Q000175:diagnosis*; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology*; D013792:Thalidomide / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D006495:Heparin, Low-Molecular-Weight; D013792:Thalidomide; D003907:Dexamethasone