title: Dissolving collagen fillers: enzymatic degradation of some problematic filler circumstances may now include collagens.
abstract: The market for non-permanent fillers has grown dramatically over the past years. Even though hyaluronic acid fillers and collagen are forgiving, complications, albeit rare, still occur. Up to now, a necessary element of any dermatologic surgeons' office is a hyaluronidase in case one of these complications should occur. However, these agents will only work on hyaluronic acid fillers leaving any problem with collagen products to be resolved by other means. Later this year the first collagenase could be approved for usage in specific medical conditions; at that time it will, perhaps, complement its hyaluronidase counterpart.
authors.affiliation: University of Alabama in Procedural Dermatology, Birmingham, AL, USA. Wil.tutrone@gmail.com
authors.forename: William D
authors.initials: WD
authors.lastname: Tutrone
authors.forename: Joel L
authors.initials: JL
authors.lastname: Cohen
mesh_terms: D003094:Collagen / Q000008:administration & dosage*; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D007267:Injections; D015595:Skin Aging / Q000187:drug effects*
chemical_list: D006820:Hyaluronic Acid; D003094:Collagen