title: Highly efficient synthesis of medium-sized lactones via oxidative lactonization: concise total synthesis of isolaurepan.
abstract: A catalytic amount of TEMPO in the presence of PhI(OAc)(2) effected oxidative lactonization of 1,6- and 1,7-diols, directly affording seven- and eight-membered lactones, respectively, in good yields.
authors.affiliation: Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, 1-1 Tsutsumidori-amamiya, Aoba-ku, Sendai 981-8555, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Ebine
authors.forename: Yuto
authors.initials: Y
authors.lastname: Suga
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Fuwa
authors.forename: Makoto
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D002384:Catalysis; D003497:Cyclic N-Oxides; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D003497:Cyclic N-Oxides; D007783:Lactones; C003959:TEMPO