title: IVF outcome in women with PCOS, PCO and normal ovarian morphology.
abstract: OBJECTIVE
  To examine the outcome of IVF in women who have normal ovaries, ovulatory PCO or PCOS.
  
  
  METHODS
  Analysis of a prospectively collected database in an assisted conception unit in a university teaching hospital including 290 women <37 years of age undergoing their first IVF cycle. The main outcome measure was severe OHSS requiring hospitalization.
  
  
  RESULTS
  Severe OHSS rates were significantly higher in women with PCO (12.6%) and PCOS (15.4%) compared to those with normal ovaries (2.7%). Coasting was used significantly more often. Live birth rates per cycle started are similar among women with PCO (38%), PCOS (37%) and normal ovaries (40%).
  
  
  CONCLUSIONS
  Women with ovaries of polycystic morphology are at increased risk of developing severe OHSS and of requiring avoidance techniques such as coasting, regardless of ovulatory status. However, live birth rates per cycle are similar to women with normal ovaries.
authors.affiliation: Royal Berkshire Hospital, Reading, RG1 5AN, UK.
authors.forename: Alexander
authors.initials: A
authors.lastname: Swanton
authors.affiliation: Oxford Fertility Unit, Institute of Reproductive Sciences, Oxford Business Park North, Oxford, Oxfordshire, OX4 2HW, UK.
authors.forename: Lisa
authors.initials: L
authors.lastname: Story
authors.affiliation: Oxford Fertility Unit, Institute of Reproductive Sciences, Oxford Business Park North, Oxford, Oxfordshire, OX4 2HW, UK.
authors.forename: Enda
authors.initials: E
authors.lastname: McVeigh
authors.affiliation: Oxford Fertility Unit, Institute of Reproductive Sciences, Oxford Business Park North, Oxford, Oxfordshire, OX4 2HW, UK. Electronic address: tim.child@obs-gyn.ox.ac.uk.
authors.forename: Tim
authors.initials: T
authors.lastname: Child
mesh_terms: D000328:Adult; D016208:Databases, Factual; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D016471:Ovarian Hyperstimulation Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D010053:Ovary / Q000000981:diagnostic imaging*; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D011446:Prospective Studies; D012044:Regression Analysis; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014463:Ultrasonography