Ion Channels as Therapeutic Targets--CHI's Fourth Annual Conference.
The Ion Channels as Therapeutic Targets meeting, held in Boston, included topics covering new therapeutic developments in the field of ion-channel drug discovery. This conference report highlights selected presentations on sensory transient receptor potential channels, potassium-channel modulation, as well as methods for chloride-channel screening and channel occupancy evaluation. Human genetic mutations observed in channelopathies and methods to predict the cardiovascular safety of ion-channel modulators were also discussed.
Thorneloe
Kevin S
KS
GlaxoSmithKline plc, 709 Swedeland Road, King of Prussia, PA 19406, USA. kevin.s.thorneloe@gsk.com
D000818:Animals; D053447:Channelopathies / Q000235:genetics; D018118:Chloride Channels / Q000187:drug effects / Q000378:metabolism; D016503:Drug Delivery Systems; D015195:Drug Design; D006801:Humans; D007473:Ion Channels / Q000187:drug effects* / Q000378:metabolism; D009154:Mutation; D015221:Potassium Channels / Q000187:drug effects / Q000378:metabolism; D050051:Transient Receptor Potential Channels / Q000187:drug effects / Q000378:metabolism
D018118:Chloride Channels; D007473:Ion Channels; D015221:Potassium Channels; D050051:Transient Receptor Potential Channels