title: Lymph node dissection in the surgical management of atypical endometrial hyperplasia.
abstract: OBJECTIVE
  The aim of this study was to evaluate the effect of lymph node dissection in patients with atypical endometrial hyperplasia.
  
  
  METHODS
  Patients undergoing surgical management of atypical endometrial hyperplasia during the study period were retrospectively identified. Clinical and pathologic information was analyzed.
  
  
  RESULTS
  Eighty-eight patients comprised our cohort. Median age was 54 years (range, 37-85 years). Sixty-seven patients had lymph node dissection at the time of surgery for atypical endometrial hyperplasia, whereas 21 did not. Twenty-five of 88 (28.4%) had endometrial carcinoma on final uterine pathology. Stages were as follows: 4 IA, 15 IB, 3 IC, 2 IIB, and 1 IIIC. Surgical outcomes were not statistically significant between staged and unstaged groups. Information from lymph node dissection influenced management decisions in 7 of the 25 (28%) cancer patients.
  
  
  CONCLUSIONS
  Lymph node dissection did not adversely affect surgical outcomes in patients with atypical endometrial hyperplasia. Because many of these patients have concurrent endometrial cancer, we recommend consideration of lymph node dissection in atypical endometrial hyperplasia patients undergoing definitive surgical treatment.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, North Shore University Hospital, Manhasset, NY, USA.
authors.forename: Jill S
authors.initials: JS
authors.lastname: Whyte
authors.forename: Elizabeth P
authors.initials: EP
authors.lastname: Gurney
authors.forename: John P
authors.initials: JP
authors.lastname: Curtin
authors.forename: Stephanie V
authors.initials: SV
authors.lastname: Blank
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004714:Endometrial Hyperplasia / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged