title: Pharmacodynamics of kardos administered as monotherapy and in combination with hypothiazide and enalapril in grade I-II arterial hypertension.
abstract: Therapy with kardos produced an antiihypertensve effect in patients with grade I-II arterial hypertension. This antiihypertensve effect was considerably potentiated, when kardos was administered in combination with enalapril.
authors.affiliation: Department of Clinical Pharmacology and Allergology with a Course of Intensive Care, Faculty of Continuous Medical Education, Volgograd Medical University, Federal Agency for Health Care and Social Development.
authors.forename: V I
authors.initials: VI
authors.lastname: Petrov
authors.forename: O I
authors.initials: OI
authors.lastname: Epshtein
authors.forename: S A
authors.initials: SA
authors.lastname: Sergeeva
authors.forename: P A
authors.initials: PA
authors.lastname: Bakumov
authors.forename: E A
authors.initials: EA
authors.lastname: Zernyukova
authors.forename: Yu A
authors.initials: YA
authors.lastname: Zabolotneva
authors.forename: M V
authors.initials: MV
authors.lastname: Kachanova
authors.forename: L B
authors.initials: LB
authors.lastname: Sabanov
mesh_terms: D000906:Antibodies / Q000097:blood / Q000276:immunology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000097:blood / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000097:blood / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D044140:Receptor, Angiotensin, Type 1 / Q000737:chemistry / Q000276:immunology; D016896:Treatment Outcome
chemical_list: D000906:Antibodies; D000959:Antihypertensive Agents; D044140:Receptor, Angiotensin, Type 1; D006852:Hydrochlorothiazide; D004656:Enalapril