title: Ex vivo lung perfusion: initial Brazilian experience.
abstract: In the last 20 years, lung transplantation has become the standard treatment for patients with end-stage lung disease. However, less than 20% of the donor lungs available for transplant are actually usable. This disparity between the growing number of recipients and the small number of donors has resulted in increased mortality among lung transplant candidates on waiting lists. Strategies such as the utilization of organs from marginal donors have proven ineffective in increasing the number of transplants. In 2000, a new method for reconditioning human lungs that had been previously rejected for transplantation was developed in Sweden. We describe our initial experience with ex vivo lung perfusion.
authors.affiliation: Department of Thoracic Surgery, University of São Paulo School of Medicine, São Paulo, Brazil. paulopego@incor.usp.br
authors.forename: Paulo Manuel
authors.initials: PM
authors.lastname: Pêgo-Fernandes
authors.forename: Israel Lopes de
authors.initials: IL
authors.lastname: Medeiros
authors.forename: Alessandro Wasum
authors.initials: AW
authors.lastname: Mariani
authors.forename: Flávio Guimarães
authors.initials: FG
authors.lastname: Fernandes
authors.forename: Fernando do Valle
authors.initials: Fdo V
authors.lastname: Unterpertinger
authors.forename: Marcos Naoyuki
authors.initials: MN
authors.lastname: Samano
authors.forename: Eduardo de Campos
authors.initials: Ede C
authors.lastname: Werebe
authors.forename: Fábio Biscegli
authors.initials: FB
authors.lastname: Jatene
mesh_terms: D000368:Aged; D001938:Brazil; D046148:Donor Selection; D006801:Humans; D008168:Lung; D016040:Lung Transplantation; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D010477:Perfusion / Q000295:instrumentation / Q000379:methods*