Whole-genome cancer analysis as an approach to deeper understanding of tumour biology.
Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration of these data sets with well-annotated phenotypic and clinical data will expedite improved interventions based on the individual genomics of the patient and the specific disease.
Strausberg
R L
RL
J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA. RLS@jcvi.org
Simpson
A J G
AJ
D020869:Gene Expression Profiling; D055106:Genome-Wide Association Study; D006801:Humans; D009369:Neoplasms / Q000235:genetics*