title: Dexmedetomidine: perioperative applications in children.
abstract: Dexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.
authors.affiliation: Department of Anaesthesiology, Queen Mary Hospital, Pokfulam, Hong Kong, China. vtang131@hku.hk
authors.forename: Vivian Man Ying
authors.initials: VM
authors.lastname: Yuen
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000494:pharmacology; D001007:Anxiety / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D003693:Delirium / Q000517:prevention & control; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007223:Infant; D010149:Postoperative Pain / Q000517:prevention & control; D019990:Perioperative Care; D011229:Preanesthetic Medication / Q000379:methods
chemical_list: D000316:Adrenergic alpha-Agonists; D020927:Dexmedetomidine