title: A rapid malaria appraisal in the Venezuelan Amazon.
abstract: BACKGROUND
  While the federal state of Amazonas bears the highest risk for malaria in Venezuela (2007: 68.4 cases/1000 inhabitants), little comprehensive information about the malaria situation is available from this area. The purpose of this rapid malaria appraisal (RMA) was to provide baseline data about malaria and malaria control in Amazonas.
  
  
  METHODS
  The RMA methodology corresponds to a rapid health impact assessment (HIA) as described in the 1999 Gothenburg consensus. In conjunction with the actors of the malaria surveillance system, all useful data and information, which were accessible within a limited time-frame of five visits to Amazonas, were collected, analysed and interpreted.
  
  
  RESULTS
  Mortality from malaria is low (< 1 in 105) and slide positivity rates have stayed at the same level for the last two decades (15% +/- 6% (SD)). Active case detection accounts for ca. 40% of slides taken. The coverage of the censured population with malaria notification points (NPs) has been achieved in recent years. The main parasite is Plasmodium vivax (84% of cases). The proportion of Plasmodium falciparum is on the decline, possibly driven by the introduction of cost-free artemisinin-based combination therapy (ACT) (1988: 33.4%; 2007: 15.4%). Monitoring and documentation is complete, systematic and consistent, but poorly digitalized. Malaria transmission displayed a visible lag behind rainfall in the capital municipality of Atures, but not in the other municipalities. In comparison to reference microscopy, quality of field microscopy and rapid diagnostic tests (RDTs) is suboptimal (kappa < 0.75). Hot spots of malaria risk were seen in some indigenous ethnic groups. Conflicting strategies in respect of training of community health workers (CHW) and the introduction of new diagnostic tools (RDTs) were observed.
  
  
  CONCLUSIONS
  Malaria control is possible, even in tropical rain forest areas, if the health system is working adequately. Interventions have to be carefully designed and the features of the particular local Latin American context considered.
authors.affiliation: Servicio Autónomo Centro Amazónico para la Investigación y Control de Enfermedades Tropicales, Simón Bolívar' (SACAICET), Puerto Ayacucho, Estado Amazonas, Venezuela.
authors.forename: Wolfram G
authors.initials: WG
authors.lastname: Metzger
authors.forename: Anibal M
authors.initials: AM
authors.lastname: Giron
authors.forename: Sarai
authors.initials: S
authors.lastname: Vivas-Martínez
authors.forename: Julio
authors.initials: J
authors.lastname: González
authors.forename: Antonio J
authors.initials: AJ
authors.lastname: Charrasco
authors.forename: Benjamin G
authors.initials: BG
authors.lastname: Mordmüller
authors.forename: Magda
authors.initials: M
authors.lastname: Magris
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003955:Diagnostic Tests, Routine / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000469:parasitology; D008853:Microscopy / Q000379:methods; D008875:Middle Aged; D009032:Mosquito Control / Q000379:methods; D010963:Plasmodium falciparum / Q000302:isolation & purification*; D010966:Plasmodium vivax / Q000302:isolation & purification*; D011446:Prospective Studies; D011933:Reagent Kits, Diagnostic / Q000469:parasitology / Q000592:standards; D012189:Retrospective Studies; D014687:Venezuela / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000962:Antimalarials; D011933:Reagent Kits, Diagnostic