Enzyme logic gate associated with a single responsive microparticle: scaling biocomputing to microsize systems.
A microsize biocomputing system based on enzyme logic processing biochemical signals was developed. Optical transduction of pH signals generated in situ by the enzyme OR logic gate was achieved with the use of a single optode microparticle.
Bychkova
Valeriya
V
Department of Chemistry, and NanoBio Laboratory, Oregon State University, Corvallis, OR 97331, USA.
Shvarev
Alexey
A
Zhou
Jian
J
Pita
Marcos
M
Katz
Evgeny
E
D000818:Animals; D055162:Biocatalysis; D004950:Esterases / Q000737:chemistry* / Q000378:metabolism; D005949:Glucose Oxidase / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008904:Miniaturization; D010316:Particle Size; D013050:Spectrometry, Fluorescence; D013552:Swine; D014510:Urease / Q000737:chemistry* / Q000378:metabolism
D005949:Glucose Oxidase; D004950:Esterases; D014510:Urease