title: [A case of cancer successfully treated by chemotherapy of S-1 as first-line chemotherapy].
abstract: The patient was an 83-year-old man who had undergone pancreaduodenectomy for a diagnosed lower bile duct cancer in April 2004. CT demonstrated intra-abdominal lymph node enlargement 2 years postoperatively and CA19-9 increased. S-1, an oral fluoropyrimidine anticancer drug, was started as first-line chemotherapy. A complete response was confirmed after the first two courses of S-1 monotherapy. CR persisted for 2 years and S-1 was discontinued after 25th course because of long CR. No grade 3 or more toxicities were noted.
authors.affiliation: Dept. of Surgery, Kurashiki Central Hospital.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kadono
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Kawamoto
authors.forename: Tebun
authors.initials: T
authors.lastname: Park
mesh_terms: D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001650:Bile Duct Neoplasms / Q000188:drug therapy* / Q000601:surgery; D004338:Drug Combinations; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D010094:Oxonic Acid / Q000627:therapeutic use*; D016577:Pancreaticoduodenectomy; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid