title: Wound botulism complicating internal fixation of a complex radial fracture.
abstract: Botulism developed in a patient following surgical repair of an open radial fracture. Symptoms resolved after treatment with antitoxin and antibiotics, and hardware excision was deferred. Subsequent osteomyelitis necessitated hardware exchange, and wound cultures grew Clostridium argentinense. This case highlights the management of botulism associated with orthopedic hardware.
authors.affiliation: Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA. steve.taylor@duke.edu
authors.forename: Steve M
authors.initials: SM
authors.lastname: Taylor
authors.forename: Cameron R
authors.initials: CR
authors.lastname: Wolfe
authors.forename: Terry C
authors.initials: TC
authors.lastname: Dixon
authors.forename: David S
authors.initials: DS
authors.lastname: Ruch
authors.forename: Gary M
authors.initials: GM
authors.lastname: Cox
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001904:Botulinum Antitoxin / Q000627:therapeutic use; D001906:Botulism / Q000175:diagnosis* / Q000382:microbiology; D003013:Clostridium / Q000302:isolation & purification*; D050723:Fractures, Bone / Q000150:complications* / Q000601:surgery*; D005597:Fractures, Open / Q000150:complications* / Q000601:surgery*; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000601:surgery; D016459:Prosthesis-Related Infections; D014946:Wound Infection / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D001904:Botulinum Antitoxin