Signal molecule-mediated hepatic cell communication during liver regeneration.
Liver regeneration is a complex and well-orchestrated process, during which hepatic cells are activated to produce large signal molecules in response to liver injury or mass reduction. These signal molecules, in turn, set up the connections and cross-talk among liver cells to promote hepatic recovery. In this review, we endeavor to summarize the network of signal molecules that mediates hepatic cell communication in the regulation of liver regeneration.
Zheng
Zhen-Yu
ZY
School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Weng
Shun-Yan
SY
Yu
Yan
Y
D000818:Animals; D022781:Hepatocytes / Q000166:cytology / Q000502:physiology*; D006801:Humans; D008099:Liver / Q000166:cytology / Q000502:physiology; D008115:Liver Regeneration / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology