Fluorescent mimics of 5-hydroxytryptamine based on N-alkylated derivatives of 6-hydroxycarbostyril.
Fluorescent probes based on a 6-hydroxycarbostyril core accumulate inside neurons and astroglia in the absence of a serotonin uptake inhibitor.
Micotto
Teresa L
TL
Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33124, USA.
Brown
Adrienne S
AS
Wilson
James N
JN
D000818:Animals; D001253:Astrocytes / Q000187:drug effects; D002645:Chickens; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006912:Hydroxyquinolines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects; D015363:Quinolones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D012701:Serotonin / Q000737:chemistry*; D050486:Serotonin Plasma Membrane Transport Proteins / Q000737:chemistry / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
D005456:Fluorescent Dyes; D006912:Hydroxyquinolines; D015363:Quinolones; D012701:Serotonin; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; C010064:carbostyril