title: Treatment of vancomycin-intermediate Staphylococcus aureus (VISA) endocarditis with linezolid.
abstract: We report a case of infective endocarditis due to vancomycin-intermediate Staphylococcus aureus (VISA). This was treated with a combination of intravenous linezolid and fusidic acid. Cure was achieved without surgical intervention.
authors.affiliation: Infectious Diseases Unit, Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Al-Khod 123, Muscat, Oman. balkhair2000@hotmail.com
authors.forename: Abdullah
authors.initials: A
authors.lastname: Balkhair
authors.forename: Zakariya
authors.initials: Z
authors.lastname: Al Muharrmi
authors.forename: Laila
authors.initials: L
authors.lastname: Darwish
authors.forename: Hatem
authors.initials: H
authors.lastname: Farhan
authors.forename: Mansour
authors.initials: M
authors.lastname: Sallam
mesh_terms: D000081:Acetamides / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D005672:Fusidic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D000069349:Linezolid; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000382:microbiology; D023303:Oxazolidinones / Q000008:administration & dosage / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D020713:Vancomycin Resistance
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D005672:Fusidic Acid; D000069349:Linezolid