title: Comparison of 4 cm Z-axis and 16 cm Z-axis multidetector CT perfusion.
abstract: OBJECTIVE
  The aim of the study was to compare 4 cm with 16 cm Z-axis coverage in the assessment of brain CT perfusion (CTP) using. 320 slice multidetector CT METHODS: A retrospective non-randomised review of CTP performed on MD320 CT between September 2008 and January 2009 was undertaken. Two experienced readers reviewed the studies along with the 4 cm and 16 cm Z-axis CTP image data set. The outcome parameters assessed were the extent of the original finding, any additional findings and a change of diagnosis.
  
  
  RESULTS
  14 out of 27 patients were found to have abnormal CTP (mean age 58.1 years, 9 male). The 16 cm Z-axis increased the accuracy of the infarct core in 78% and ischaemic penumbra quantification in 100% of the cases. It also diagnosed additional infarcts in the same vascular territory in 28% of cases and in a different vascular territory in 14%.
  
  
  CONCLUSIONS
  The increased field of view with MD320 better defines the true extent of the infarct core and ischaemic penumbra. It also identified other areas of infarction that were not identified on the 4 cm Z-axis.
authors.affiliation: Department of Diagnostic Imaging, Southern Health Network, Monash Medical Centre, 246 Clayton Rd, Clayton, 3168 Victoria, Australia.
authors.forename: Mark
authors.initials: M
authors.lastname: Page
authors.forename: Dee
authors.initials: D
authors.lastname: Nandurkar
authors.forename: Marcus Peter
authors.initials: MP
authors.lastname: Crossett
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Stuckey
authors.forename: Kenneth P
authors.initials: KP
authors.lastname: Lau
authors.forename: Nicholas
authors.initials: N
authors.lastname: Kenning
authors.forename: John M
authors.initials: JM
authors.lastname: Troupis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055420:Perfusion Imaging / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*