[Apoptosis during embryo development].
The development of human embryo includes two essential processes, i.e., rapid mitotic activity of cells and gradual differentiation of tissues and organs. The latter process is very often characterized by extensive migration of cells from their site of origin to the site of definitive location, inductive action of the neighboring germ layers and programmed cell death (apoptosis). This paper describes examples of proliferative and apoptotic processes during the development of human embryo. The development of trilaminar germ disk, skin, gonads, central and peripheral nerve system as well as limbs provides instructive examples of how apoptosis regulates the development and differentiation of cells.
Jezek
Davor
D
Department of Histology and Embryology, School of Medicine, University of Zagreb, Zagreb, Croatia. davor@mef.hr
Kozina
Viviana
V
D017209:Apoptosis / Q000502:physiology*; D047108:Embryonic Development / Q000502:physiology*; D006801:Humans