Nonhemolytic Streptococcus pyogenes isolates that lack large regions of the sag operon mediating streptolysin S production.
Among nonhemolytic Streptococcus pyogenes (group A streptococcus) strains (n = 9) isolated from patients with pharyngitis or acute otitis media, we identified three deletions in the region from the epf gene, encoding the extracellular matrix binding protein, to the sag operon, mediating streptolysin S production.
Yoshino
Miho
M
Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Murayama
Somay Y
SY
Sunaoshi
Katsuhiko
K
Wajima
Takeaki
T
Takahashi
Miki
M
Masaki
Junko
J
Kurokawa
Iku
I
Ubukata
Kimiko
K
D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005260:Female; D006460:Hemolysin Proteins / Q000096:biosynthesis; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009876:Operon; D010033:Otitis Media / Q000382:microbiology; D010612:Pharyngitis / Q000382:microbiology; D017422:Sequence Analysis, DNA; D017384:Sequence Deletion; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000235:genetics* / Q000302:isolation & purification*; D013301:Streptolysins / Q000235:genetics*
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D006460:Hemolysin Proteins; D013301:Streptolysins; C026050:streptolysin S