Ni(II)-catalyzed enantioselective conjugate addition of acetylenes to alpha,beta-enones.
Alkynylaluminum reagents undergo enantioselective conjugate addition to cyclic alpha,beta-enones in the presence of chiral bisphosphine complexes of Ni(II).
Larionov
Oleg V
OV
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Corey
E J
EJ
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D007659:Ketones; D009942:Organometallic Compounds; D009532:Nickel