title: Spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester of pregnancy.
abstract: OBJECTIVE
  To compare the spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester pregnant and non-pregnant women.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  44 ASA physical status I and II women patients, 22 of whom were in their second trimester of pregnancy undergoing cervical cerclage, and 22 non-pregnant women scheduled for perianal surgery.
  
  
  METHODS
  The extent of sensory block and hemodynamic changes were assessed.
  
  
  METHODS
  Number of dermatomes blocked was determined by testing for pinprick; systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured at 3, 5, 10, 15, 30 and 60 minutes.
  
  
  RESULTS
  Maximal sensory block was higher in the second trimester of the pregnant group by three dermatomes than the non-pregnant group. There were no statistically significant differences in SBP, DBP, or HR changes between the groups.
  
  
  CONCLUSIONS
  Pregnant women in the second trimester exhibit enhanced spread of spinal analgesia with hyperbaric bupivacaine more so than non-pregnant women.
authors.affiliation: Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea. lgyanes@ewha.ac.kr
authors.forename: Guie Y
authors.initials: GY
authors.lastname: Lee
authors.forename: Chi H
authors.initials: CH
authors.lastname: Kim
authors.forename: Rack K
authors.initials: RK
authors.lastname: Chung
authors.forename: Jong I
authors.initials: JI
authors.lastname: Han
authors.forename: Dong Y
authors.initials: DY
authors.lastname: Kim
mesh_terms: D000328:Adult; D000779:Anesthetics, Local; D001794:Blood Pressure / Q000187:drug effects; D002045:Bupivacaine; D002584:Cervix Uteri / Q000601:surgery; D005260:Female; D013509:Gynecologic Surgical Procedures; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009046:Motor Neurons / Q000187:drug effects; D009407:Nerve Block; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000502:physiology*; D013346:Subarachnoid Space
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine