The use of ultralow doses of antibodies to C-terminal fragment of angiotensin II AT1 receptor (kardos) in the therapy of arterial hypertension.
Kardos monotherapy allows attaining the target levels of systolic and diastolic blood pressure in patients with high-risk and very-high-risk hypertension. We demonstrated excellent tolerability of the preparation in combination with reliable blood pressure decrease over 24 h, during day and night hours.
Petrov
V I
VI
Volgograd State Medical University, Federal Agency for Health Care and Social Development.
Nedogoda
S V
SV
Epshtein
O I
OI
Chalyabi
T A
TA
Brel'
U A
UA
Chepurina
N G
NG
Mazina
G V
GV
Kachanova
M V
MV
Sabanov
L V
LV
Tarasov
S A
SA
Zabolotneva
Yu A
YA
Kolosova
A E
AE
Sergeeva
S A
SA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000008:administration & dosage / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011945:Receptors, Angiotensin / Q000737:chemistry* / Q000276:immunology*; D016896:Treatment Outcome; D055815:Young Adult
D000906:Antibodies; D000959:Antihypertensive Agents; D011945:Receptors, Angiotensin