title: Churg-strauss syndrome presenting with cardiac mass and right ventricular obstruction.
abstract: A 57-year-old woman presenting with asthma, hypereosinophilia, and generalized unspecific symptoms was diagnosed with Churg-Strauss syndrome. Echocardiography revealed a cardiac mass obliterating the right ventricle and severely impaired left ventricular function, which were caused by endomyocardial fibrosis. Cortisone and cyclophosphamide therapy resulted in amelioration of left ventricular function and significant size reduction of the right ventricular mass.
authors.affiliation: First Department of Medicine, Division of Cardiology, University Hospital of Jena. Germany
authors.forename: Sylvia
authors.initials: S
authors.lastname: Otto
authors.forename: Hans R
authors.initials: HR
authors.lastname: Figulla
authors.forename: Björn
authors.initials: B
authors.lastname: Goebel
authors.forename: Peter
authors.initials: P
authors.lastname: Oelzner
authors.forename: Tudor C
authors.initials: TC
authors.lastname: Poerner
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D015267:Churg-Strauss Syndrome / Q000175:diagnosis*; D003348:Cortisone / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D003952:Diagnostic Imaging; D004719:Endomyocardial Fibrosis / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D013927:Thrombosis / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology; D014694:Ventricular Outflow Obstruction / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D003348:Cortisone