The use of anaferon (pediatric formulation) for prophylaxis of acute respiratory viral infections in preschool children.
Anaferon (pediatric formulation) reduces the incidence of acute respiratory viral infections in sickly children and children with bronchial asthma and has a positive effect on the course of asthma. The preparation produces an immunomodulating effect (increases initially low IFN-gamma levels and normalizes elevated levels of IL-1beta), stimulates synthesis of IgA and IgG, exhibits cytoprotective activity, and improves local immunity of the upper airways in sickly children.
Kondrat'eva
E I
EI
Siberian State Medical Universoty, Federal Agency for Health Care and Social Development, Tomsk.
Matveeva
L A
LA
Shemyakina
T A
TA
Logvinenko
Yu I
YI
Golikova
E V
EV
Kutuzova
E B
EB
D000906:Antibodies / Q000494:pharmacology / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007070:Immunoglobulin A / Q000097:blood / Q000378:metabolism; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism; D007371:Interferon-gamma / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D008297:Male; D012141:Respiratory Tract Infections / Q000097:blood* / Q000188:drug therapy / Q000378:metabolism / Q000517:prevention & control*; D016896:Treatment Outcome
D000906:Antibodies; D000998:Antiviral Agents; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D053583:Interleukin-1beta; C547732:anaferon; D007371:Interferon-gamma