RNA degradation in yeast and human mitochondria.
RNA turnover in yeast mitochondria is controlled by the complex called degradosome, which consists of two nuclear-encoded proteins: the SUV3 gene codes for an RNA helicase and the DSS1 gene codes for an RNase. In contrast to yeast, much less is known about RNA degradation in human mitochondria. We suggest that the key enzyme involved in this process is nuclear-encoded polynucleotide phosphorylase, hPNPase.
Piwowarski
Jan
J
Department of Genetics, Warsaw University and Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Dziembowski
Andrzej
A
Dmochowska
Aleksandra
A
Minczuk
Michal
M
Tomecki
Rafal
R
Gewartowski
Kamil
K
Stepien
Piotr P
PP