The enigmatic roles of microglial versus neuronal progranulin in neurological disease.
Eriksen
Jason L
JL
Pharmacological and Pharmaceutical Science, University of Houston, Houston, TX 77204, USA. jeriksen@central.uh.edu
D000818:Animals; D001921:Brain / Q000378:metabolism; D057174:Frontotemporal Lobar Degeneration / Q000235:genetics / Q000378:metabolism*; D000077155:Granulins; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism*; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D017628:Microglia / Q000378:metabolism*; D009154:Mutation; D009474:Neurons / Q000378:metabolism*; D000077153:Progranulins; D013116:Spinal Cord / Q000378:metabolism; D013119:Spinal Cord Injuries / Q000235:genetics / Q000378:metabolism*
C492314:GRN protein, human; D000077155:Granulins; C120204:Grn protein, mouse; D036341:Intercellular Signaling Peptides and Proteins; D000077153:Progranulins