title: High-content screening: a decade of evolution.
abstract: In the past decade, high-content screening has become a highly developed approach to obtaining richly descriptive quantitative phenotypic data using automated microscopy. From early use in drug screening, the technique has evolved to embrace a diverse range of applications in both academic and industrial sectors and is now widely recognized as providing an efficient and effective approach to large-scale programs investigating cell biology in situ and in context.
authors.affiliation: GE Healthcare, Whitchurch, Cardiff, United Kingdom. nick.thomas@ge.com
authors.forename: Nick
authors.initials: N
authors.lastname: Thomas
mesh_terms: D002477:Cells / Q000378:metabolism; D057166:High-Throughput Screening Assays / Q000379:methods* / Q000639:trends*; D006801:Humans