[Diagnostic value of double contrast-enhanced ultrasonography in preoperative staging of gastric cancer].
OBJECTIVE
To evaluate the clinical value of double contrast-enhanced ultrasonography using oral and intravenous contrast agents in preoperative staging of gastric cancer.


METHODS
Sixty-two patients with biopsy-proven gastric cancer were enrolled into this study, and were examined by double contrast-enhanced gastric ultrasonography preoperatively. The results were compared with postoperative pathologic findings.


RESULTS
The accuracy of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in determining the T stage of gastric cancer was 72.9% (T1: 66.7%, T2: 60.0%, T3: 76.9%, T4: 71.4%) and 88.1% (T1: 66.7%, T2: 80.0%, T3: 89.7%, T4: 100%), respectively, with a statistically significant difference between the two methods (P = 0.036). The sensitivity, specificity, accuracy and Youden index of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in assessment of lymph node metastasis were 74.5%, 66.7%, 72.9%, and 0.41 versus 89.4%, 75.0%, 86.4%, 0.76, respectively. No significant difference in the accuracy of assessment for lymph node metastasis was observed (P > 0.05).


CONCLUSIONS
Double contrast-enhanced ultrasonography is useful for preoperative staging of gastric cancer, especially for T staging.
Wang
Cheng-long
CL
Department of General Surgery, Lin'an People's Hospital, Lin'an, Zhejiang, China.
Yang
Yong-ming
YM
Cui
Jian
J
Ouyang
Hong
H
Wang
Zhe-min
ZM
Ye
Huai-song
HS
Ruan
Hua-juan
HJ
Zheng
Zhi-qiang
ZQ
D000328:Adult; D000368:Aged; D003287:Contrast Media; D019160:Endosonography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D011300:Preoperative Care; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D013459:Sulfur Hexafluoride
D003287:Contrast Media; D013459:Sulfur Hexafluoride