title: Clinical effect of a topical herbal ointment on pain in temporomandibular disorders: a randomized placebo-controlled trial.
abstract: OBJECTIVE
  The aim of this study was to compare the effectiveness of using Ping On ointment and using petroleum jelly in the treatment of temporomandibular joint (TMJ) and masticatory muscle pain, in order to establish the true efficacy of Ping On ointment.
  
  
  METHODS
  In this randomized, double-blinded, placebo-controlled trial, 55 subjects with TMJ and/or masticatory pain (Group I patients according to the Research Diagnostic Criteria for Temporomandibular Disorder (RDC/TMD) received Ping On ointment for 4 weeks, or placebo for 4 weeks. Subjects were evaluated with standard measures of efficacy: pain intensity measured by visual analogue scale and maximal comfortable mandibular opening, at baseline and again after 4 weeks of treatment.
  
  
  RESULTS
  Ping On ointment significantly reduced the symptoms of painful TMJs and/or masticatory muscles. Maximal comfortable mandibular opening also improved in the Ping On ointment group compared with the placebo, but was not clinically significant.
  
  
  CONCLUSIONS
  This preliminary study suggests that topical application of Ping On ointment may be considered for further investigation as a potential first-line treatment modality, before prescribing analgesics, for the management of TMDs. It is topically applied, safe, reversible, and effective in managing TMDs and masticatory muscle pain.
authors.affiliation: Orthodontics Department, University of Hong Kong 2/F, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong.
authors.forename: Larry C F
authors.initials: LC
authors.lastname: Li
authors.forename: Ricky W K
authors.initials: RW
authors.lastname: Wong
authors.forename: A Bakr M
authors.initials: AB
authors.lastname: Rabie
mesh_terms: D000287:Administration, Topical; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008410:Masticatory Muscles / Q000187:drug effects*; D008875:Middle Aged; D009824:Ointments; D010146:Pain / Q000188:drug therapy*; D013704:Temporomandibular Joint / Q000187:drug effects*; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal; D009824:Ointments