Structural prediction and analysis of VIH-related peptides from selected crustacean species.
The tentative elucidation of the 3D-structure of vitellogenesis inhibiting hormone (VIH) peptides is conversely underprivileged by difficulties in gaining enough peptide or protein, diffracting crystals, and numerous extra technical aspects. As a result, no structural information is available for VIH peptide sequences registered in the Genbank. In this situation, it is not surprising that predictive methods have achieved great interest. Here, in this study the molt-inhibiting hormone (MIH) of the kuruma prawn (Marsupenaeus japonicus) is used, to predict the structure of four VIHrelated peptides in the crustacean species. The high similarity of the 3D-structures and the calculated physiochemical characteristics of these peptides suggest a common fold for the entire family.
Nagaraju
Ganji Purna Chandra
GP
Kumari
Nunna Siva
NS
Prasad
Ganji Lakshmi Vara
GL
Rajitha
Balney
B
Meenu
Madan
M
Rao
Manam Sreenivasa
MS
Naik
Bannoth Reddya
BR