title: Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report.
abstract: BACKGROUND
  Patients with migraine headaches are frequently prescribed topiramate to treat their condition.
  
  
  METHODS
  We present a case of bilateral acute angle-closure glaucoma occurring 2 days after topiramate therapy was increased for symptoms related to migraine.
  
  
  CONCLUSIONS
  Acute angle-closure glaucoma secondary to topiramate is an uncommon but serious adverse reaction that may result in severe morbidity such as permanent visual loss if not recognized in a timely manner. Treatment differs from primary acute angle-closure glaucoma in that discontinuation of topiramate is necessary for the glaucoma to resolve.
authors.affiliation: Department of Emergency Medicine, Northwestern University, Chicago, Illinois 60611, USA.
authors.forename: Kendra L
authors.initials: KL
authors.lastname: Cole
authors.forename: Ernest E
authors.initials: EE
authors.lastname: Wang
authors.forename: Richard M
authors.initials: RM
authors.lastname: Aronwald
mesh_terms: D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D000077236:Topiramate
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose