title: The surgical management of granulomatous mastitis.
abstract: Granulomatous mastitis is an inflammatory breast condition of unknown etiology. Management remains controversial and treatment algorithms are lacking from the literature. Few resources exist that discuss breast reconstruction following extirpation. This descriptive case series reviews the clinicopathologic features of granulomatous mastitis.We describe the surgical management undertaken at our institution including General and Plastic Surgery procedures. Eleven clinical charts and histologic slides of biopsy specimens were reviewed in our health region between 1992 and 2007. Demographic data, clinical presentation, and radiologic findings were tabulated. Treatment consisted of empirical antibiotics and surgical excision. Procedures performed included incision and drainage (n = 8), excisional biopsy (n = 15), partial mastectomy (n = 5), partial mastectomy with reduction mammaplasty (n = 2), and mastectomy with TRAM flap reconstruction (n = 1).Treatment was successful in all but one case. Multiple surgeries for recurrent lesions were often required to achieve final remission. Following extirpation, we recommend delayed breast reconstruction to monitor for recurrence.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Vancouver, BC, Canada. farrah.yau@gmail.com
authors.forename: Farrah M
authors.initials: FM
authors.lastname: Yau
authors.forename: Sheina A
authors.initials: SA
authors.lastname: Macadam
authors.forename: Urve
authors.initials: U
authors.lastname: Kuusk
authors.forename: Michael
authors.initials: M
authors.lastname: Nimmo
authors.forename: Nancy
authors.initials: N
authors.lastname: Van Laeken
mesh_terms: D000328:Adult; D001706:Biopsy; D001940:Breast / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D015413:Mastectomy, Simple; D008413:Mastitis / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology; D013210:Staphylococcus / Q000302:isolation & purification; D055815:Young Adult