title: Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data.
abstract: For Genetic Analysis Workshop 16 Problem 1, we provided data for genome-wide association analysis of rheumatoid arthritis. Single-nucleotide polymorphism (SNP) genotype data were provided for 868 cases and 1194 controls that had been assayed using an Illumina 550 k platform. In addition, phenotypic data were provided from genotyping DRB1 alleles, which were classified according to the rheumatoid arthritis shared epitope, levels of anti-cyclic citrullinated peptide, and levels of rheumatoid factor IgM. Several questions could be addressed using the data, including analysis of genetic associations using single SNPs or haplotypes, as well as gene-gene and genetic analysis of SNPs for qualitative and quantitative factors.
authors.affiliation: Departments of Epidemiology and Biomathematics, University of Texas, MD Anderson Cancer Center, 1155 Pressler Street, Houston, Texas 77030, USA. camos@mdanderson.org.
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Amos
authors.forename: Wei Vivien
authors.initials: WV
authors.lastname: Chen
authors.forename: Michael F
authors.initials: MF
authors.lastname: Seldin
authors.forename: Elaine F
authors.initials: EF
authors.lastname: Remmers
authors.forename: Kimberly E
authors.initials: KE
authors.lastname: Taylor
authors.forename: Lindsey A
authors.initials: LA
authors.lastname: Criswell
authors.forename: Annette T
authors.initials: AT
authors.lastname: Lee
authors.forename: Robert M
authors.initials: RM
authors.lastname: Plenge
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Kastner
authors.forename: Peter K
authors.initials: PK
authors.lastname: Gregersen