title: Outcomes after a decade of laparoscopic giant paraesophageal hernia repair.
abstract: OBJECTIVE
  Laparoscopic repair of giant paraesophageal hernia is a complex operation requiring significant laparoscopic expertise. Our objective was to compare our current approach and outcomes for laparoscopic repair of giant paraesophageal hernia with our previous experience.
  
  
  METHODS
  A retrospective review of patients undergoing nonemergency laparoscopic repair of giant paraesophageal hernia, stratified by early versus current era (January 1997-June 2003 and July 2003-June 2008), was performed. We evaluated clinical outcomes, barium esophagogram, and quality of life.
  
  
  RESULTS
  Laparoscopic repair of giant paraesophageal hernia was performed in 662 patients (median age 70 years, range 19-92 years) with a median percentage of herniated stomach of 70% (range 30%-100%). With time, use of Collis gastroplasty decreased (86% to 53%), as did crural mesh reinforcement (17% to 12%). Current era patients were 50% more likely to have a Charlson comorbidity index score greater than 3. Thirty-day mortality was 1.7% (11/662). Mortality and complication rates were stable with time, despite increasing comorbid disease in current era. Postoperative gastroesophageal reflux disease health-related quality of life scores were available for 489 patients (30-month median follow-up), with good to excellent results in 90% (438/489). Radiographic recurrence (15.7%) was not associated with symptom recurrence. Reoperation occurred in 3.2% (21/662).
  
  
  CONCLUSIONS
  With time, we have obtained significant minimally invasive experience and refined our approach to laparoscopic repair of giant paraesophageal hernia. Perioperative morbidity and mortality remain low, despite increased comorbid disease in the current era. Laparoscopic repair provided excellent patient satisfaction and symptom improvement, even with small radiographic recurrences. Reoperation rates were comparable to the best open series.
authors.affiliation: Division of Thoracic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: James D
authors.initials: JD
authors.lastname: Luketich
authors.forename: Katie S
authors.initials: KS
authors.lastname: Nason
authors.forename: Neil A
authors.initials: NA
authors.lastname: Christie
authors.forename: Arjun
authors.initials: A
authors.lastname: Pennathur
authors.forename: Blair A
authors.initials: BA
authors.lastname: Jobe
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Landreneau
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Schuchert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D015391:Gastroplasty / Q000706:statistics & numerical data; D006551:Hernia, Hiatal / Q000150:complications / Q000401:mortality / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013526:Surgical Mesh; D016896:Treatment Outcome