Polarity-reversible conjugate addition tuned by remote electronic effects.
A new concept, polarity-reversible conjugate addition, has been described, based on the findings that the polarity of a classical Michael acceptor can be reversed through remote electronic effects. In addition, the remote electronic effects are tunable, and both five- and six-membered nitrogen rings can be constructed starting from acyclic precursors having the same enone structure unit simply by varying a remote substituent in the molecules.
Li
Yifei
Y
Department of Chemistry, Northeast Normal University, Changchun 130024, China.
Xu
Xianxiu
X
Tan
Jing
J
Liao
Peiqiu
P
Zhang
Jingping
J
Liu
Qun
Q