title: A cradle-shaped gradient coil to expand the clear-bore width of an animal MRI scanner.
abstract: The never ending quest for higher magnetic field strengths in MRI and MRS has led to small and medium bore scanners at 9.4 T and above for both human and animal use; however, these bore diameters restrict the size of object that can be accommodated when using a conventional gradient coil. By replacing a cylindrical gradient-coil insert with a single-sided gradient coil, the scanner's functionality can be extended to include localized imaging of wider samples. As a prototype, a three-axis, cradle-shaped gradient coil was designed, fabricated and implemented in a 9.4 T animal MRI scanner. Since gradient fields are required only to be monotonic over the desired field of view, the cradle gradient coil was designed to produce high gradient efficiencies (up to 2.25 mT m(-1) A(-1) over a 5 cm imaging region) at the expense of gradient linearity. A dedicated three-dimensional algorithm was developed to correct the resultant image distortion. Preliminary images of a grid phantom and a mouse demonstrated the fidelity of the algorithm in correcting image distortion of greater than 200%. Eddy currents were measured along each gradient axis. A large 65.2 (Hz mT(-1) m) B(0) eddy current was produced by the y-axis, suggesting potential limitations of single-sided gradient coils.
authors.affiliation: Centre for Functional and Metabolic Mapping, Robarts Research Institute, The University of Western Ontario, PO Box 5015, 100 Perth Drive, London, Ontario, N6A 5K8, Canada. kgilbert@imaging.robarts.ca
authors.forename: K M
authors.initials: KM
authors.lastname: Gilbert
authors.forename: J S
authors.initials: JS
authors.lastname: Gati
authors.forename: L M
authors.initials: LM
authors.lastname: Klassen
authors.forename: R S
authors.initials: RS
authors.lastname: Menon
mesh_terms: D000465:Algorithms; D000818:Animals; D001921:Brain / Q000033:anatomy & histology; D004867:Equipment Design; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods; D051379:Mice; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging