Subtleties in asymmetric catalyst structure: the resolution of a 6-phospha-2,4,8-trioxa-adamantane and its applications in asymmetric hydrogenation catalysis.
An efficient, classical resolution of the versatile P-ligand intermediate 6-phospha-2,4,8-trioxa-adamantane (CgPH) is described and the rhodium complex of the optically pure secondary phosphine beta-CgPH is an active and moderately selective asymmetric hydrogenation catalyst.
Hopewell
Jonathan
J
School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK.
Jankowski
Piotr
P
McMullin
Claire L
CL
Orpen
A Guy
AG
Pringle
Paul G
PG