title: [Comparison of equations to estimate the glomerular filtration in people aged 75 or older without known renal disease].
abstract: OBJECTIVE
  To compare the glomerular filtration rate (GFR) of patients aged 75 and older without known renal disease estimated by the MDRD-4-IDMS (MDRD) formula, urine 24h creatinine clearance (24h-CC) and Cockroft-Gault (CG) formula.
  
  
  METHODS
  There were included 70 persons aged 75 and older from the geriatric external consultation. We compared the MDRD against the CG and the 24h-CC.
  
  
  RESULTS
  Means of GFR were: 24h-CC: 56,60 + or - 22,79 ml/min/1.73 m(2) and CG: 54,27 + or - 15,25 ml/min/1.73 m(2), significantly lower than with MDRD: 69,78 + or - 18,53 ml/min/1.73 m(2) (p<0.001). Age was correlated with the difference between CG and MDRD (coefficient of correlation: 0,59; r(2):0,34; p<0,001). Moderate agreement was obtained between MDRD with CG (k coefficient = 0.37; CI95%=0.19-0.55) and MDRD with 24-CC (k coefficient = 0.39; CI95% = 0.22-0.57).
  
  
  CONCLUSIONS
  The MDRD and CG formulas to estimate the FGR in people aged 75 and older are not interchangeable. There are needed specific studies in old people to establish the most precise formula.
authors.affiliation: Servicio de Geriatría, Hospital Central de la Cruz Roja, Madrid, España. javiergomezpavon@ya.com
authors.forename: Javier
authors.initials: J
authors.lastname: Gómez-Pavón
authors.forename: César
authors.initials: C
authors.lastname: Gálvez Barrón
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Baztán Cortés
authors.forename: Isidoro
authors.initials: I
authors.lastname: Ruipérez Cantera
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003401:Creatine / Q000652:urine; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008433:Mathematics
chemical_list: D003401:Creatine