Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids.
Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products is consistent with that of a proposed C-H insertion intermediate.
Shi
Bing-Feng
BF
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Zhang
Yang-Hui
YH
Lam
Jonathan K
JK
Wang
Dong-Hui
DH
Yu
Jin-Quan
JQ
D000447:Aldehydes / Q000138:chemical synthesis / Q000737:chemistry; D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D004158:Diphenylacetic Acids / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D000475:Alkenes; D004158:Diphenylacetic Acids; D007783:Lactones; D009942:Organometallic Compounds; D010165:Palladium