Cytokinetic astralogy.
Division plane specification in animal cells has long been presumed to involve direct contact between microtubules of the anaphase mitotic spindle and the cell cortex. In this issue, von Dassow et al. (von Dassow et al. 2009. J. Cell. Biol. doi:10.1083/jcb.200907090) challenge this assumption by showing that spindle microtubules can effectively position the division plane at a distance from the cell cortex.
Canman
Julie C
JC
Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92037, USA. jcanman@ucsd.edu
D000818:Animals; D018385:Centrosome / Q000187:drug effects / Q000502:physiology*; D048749:Cytokinesis / Q000187:drug effects; D004058:Diffusion; D004625:Embryo, Nonmammalian / Q000502:physiology; D004789:Enzyme Activation; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology; D008677:Metaphase; D008870:Microtubules / Q000187:drug effects / Q000502:physiology*; D021381:Protein Transport; D015398:Signal Transduction / Q000187:drug effects; D008941:Spindle Apparatus / Q000187:drug effects / Q000502:physiology*; D013997:Time Factors; D050257:Tubulin Modulators / Q000494:pharmacology; D020741:rho GTP-Binding Proteins / Q000378:metabolism
D056572:Histone Deacetylase Inhibitors; D050257:Tubulin Modulators; D020741:rho GTP-Binding Proteins