Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique in 2005.
Currently, Vibrio cholerae O1 serogroup biotype El Tor strains producing classical type cholera toxin (altered strains or El Tor variants) are prevalent in Asia and in Mozambique. Mozambican strains collected in 2004 contained a tandem repeat of CTX prophage on the small chromosome and each CTX prophage harboured the classical rstR and classical ctxB. We found that the majority of the strains collected in 2005 in Mozambique contained extra elements on the large chromosome in addition to the tandem repeat of CTX prophage on the small chromosome. New type RS1 elements RS1(cla) and RS1(env), and a CTX(env) with rstR(env) and the classical ctxB were identified on the large chromosome of the Mozambican isolates collected in 2005.
Choi
Seon Young
SY
School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.|International Vaccine Institute, Seoul, Republic of Korea.
Lee
Je Hee
JH
School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.|International Vaccine Institute, Seoul, Republic of Korea.
Kim
Eun Jin
EJ
International Vaccine Institute, Seoul, Republic of Korea.
Lee
Hye Ri
HR
International Vaccine Institute, Seoul, Republic of Korea.
Jeon
Yoon-Seong
YS
School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.|International Vaccine Institute, Seoul, Republic of Korea.
von Seidlein
Lorenz
L
International Vaccine Institute, Seoul, Republic of Korea.
Deen
Jaqueline
J
International Vaccine Institute, Seoul, Republic of Korea.
Ansaruzzaman
M
M
International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.
Lucas
G Marcelino E S
GMES
Ministry of Health, Maputo, Mozambique.
Barreto
Avertino
A
Ministry of Health, Maputo, Mozambique.
Songane
Francisco F
FF
Ministry of Health, Maputo, Mozambique.
Mondlane
Catarina
C
Centro de Higiene Ambiental e Exames Medicos, Beira, Mozambique.
Nair
G Balakrish
GB
National Institute of Cholera and Enteric Diseases, Kolkata, India.
Czerkinsky
Cecil
C
International Vaccine Institute, Seoul, Republic of Korea.
Clemens
John D
JD
International Vaccine Institute, Seoul, Republic of Korea.
Chun
Jongsik
J
School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.|International Vaccine Institute, Seoul, Republic of Korea.
Kim
Dong Wook
DW
International Vaccine Institute, Seoul, Republic of Korea.
D002771:Cholera / Q000453:epidemiology* / Q000382:microbiology*; D002772:Cholera Toxin / Q000235:genetics*; D002876:Chromosomes, Bacterial / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D023061:Gene Order; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D009073:Mozambique / Q000453:epidemiology; D039002:Prophages / Q000235:genetics*; D017422:Sequence Analysis, DNA; D026801:Synteny; D020080:Tandem Repeat Sequences; D041241:Vibrio cholerae O1 / Q000235:genetics* / Q000302:isolation & purification*
D004269:DNA, Bacterial; D002772:Cholera Toxin