title: Estimation of the effect size in meta-analysis with few studies.
abstract: Meta-analysis is often conducted with only a small number of studies. Adjustments of the (restricted) maximum likelihood estimator of the effect size are derived and their gains in efficiency are explored. The proposed estimators are applied to three sets of studies.
authors.affiliation: SNTL and Departament d'Economia i Empresa, Universitat Pompeu Fabra, Barcelona, Spain. ntl@sntl.co.uk
authors.forename: Nicholas T
authors.initials: NT
authors.lastname: Longford
mesh_terms: D000628:Aminophylline / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D003198:Computer Simulation; D041981:Gastrointestinal Tract / Q000382:microbiology; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D016013:Likelihood Functions; D015201:Meta-Analysis as Topic; D015233:Models, Statistical; D012140:Respiratory Tract Diseases / Q000209:etiology; D020521:Stroke / Q000188:drug therapy / Q000401:mortality
chemical_list: D001993:Bronchodilator Agents; D000628:Aminophylline; D005990:Glycerol