Mixed testicular germ cell tumor presenting as metastatic pure choriocarcinoma involving multiple lung metastases that was effectively treated with high-dose chemotherapy.
Choriocarcinoma in the testis is very rare, and it represents less than 1% (0.3%) of all the testicular germ cell tumors. It is a particularly aggressive variant of non-seminoma tumor, which is characterized by a high serum beta-HCG level and multiple lung metastases. The optimal management for this disease remains undefined. We report here on a case of choriocarcinoma with multiple lung metastases, and the patient has achieved continuous remission for 2 years after combination chemotherapy of BEP (bleomycin, etoposide and cisplatin) and sequential high-dose chemotherapy with autologous peripheral stem cell rescue.
Lee
Sang-Cheol
SC
Division of Hematology-Oncology, Department of Internal Medicine, Soonchunhyang University Hospital, Seoul, Korea.
Kim
Kyoung Ha
KH
Kim
Sung Han
SH
Lee
Nam Su
NS
Park
Hee Sook
HS
Won
Jong-Ho
JH