title: BIPASS: design of alternative splicing services.
abstract: We analyse the motivations that led the development of services to support alternative splicing studies. We discuss data modelling issues and illustrate them with the BioInformatics Pipeline for Alternative Splicing Services (BIPASS). We identify the specific needs that an alternative splicing service should address, and compare existing services with respect to a common matrix of functionalities. We conclude with a discussion on future work needed to offer a more complete suite of services.
authors.affiliation: Scientific Data Management Laboratory, Electrical Engineering, Arizona State University, Tempe AZ 85287-5706, USA. Zoe.Lacroix@asu.edu
authors.forename: Zoé
authors.initials: Z
authors.lastname: Lacroix
authors.forename: Christophe
authors.initials: C
authors.lastname: Legendre
mesh_terms: D017398:Alternative Splicing; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D005091:Exons; D007438:Introns; D008957:Models, Genetic; D022821:RNA Splice Sites; D012333:RNA, Messenger / Q000378:metabolism
chemical_list: D022821:RNA Splice Sites; D012333:RNA, Messenger