title: [Compatibility chemistry of acid-alkaline pair medicine of Dahuang and Huangbai in Dahuang Xiaoshi decoction].
abstract: OBJECTIVE
  To determine the change pattern of alkaline and acid components of Dahuang and Huangbai amoung different combinations in Dahuang Xiaoshi decotion.
  
  
  METHODS
  The contents of anthraquinones and berberine were determined by HPLC in samples of Dahuang extracts, Huangbai extracts, Dahuang and Huangbai pair medicine extracts, and extracts of whole recipe.
  
  
  RESULTS
  The contents of anthraquinones and berberine were decreased with the changes of combinations: from component medicinal material alone to pair medicines, and to whole recipe. the change pattern was more apparent in water decoctions than in ethanol extracts.
  
  
  CONCLUSIONS
  The contents of alkaline and acid components are changed with different extract methods and different combinations.
authors.affiliation: Department of Chinese Materia Medica, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China. peimr602@163.com
authors.forename: Miaorong
authors.initials: M
authors.lastname: Pei
authors.forename: Xiujun
authors.initials: X
authors.lastname: Duan
authors.forename: Xiangping
authors.initials: X
authors.lastname: Pei
mesh_terms: D000143:Acids / Q000032:analysis; D000468:Alkalies / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D032102:Phellodendron / Q000737:chemistry*; D012250:Rheum / Q000737:chemistry*
chemical_list: D000143:Acids; D000468:Alkalies; D004365:Drugs, Chinese Herbal