title: Long-term follow-up of full macular translocation for choroidal neovascularization.
abstract: OBJECTIVE
  To report the long-term (>5 years) results of full macular translocation in patients with choroidal neovascularization (CNV).
  
  
  METHODS
  Retrospective, interventional case series.
  
  
  METHODS
  This study involved 32 eyes of 32 patients who had undergone full macular translocation for CNV. The median follow-up was 6.5 years (range, 5.2 to 7.7 years). We evaluated the best-corrected visual acuity, fundus examination results obtained before and 1 and 5 years after operation, and postoperative complications.
  
  
  RESULTS
  At the 1-year follow-up, foveal retinal pigment epithelium atrophy was observed in only 3 eyes (12%), and the mean logarithm of the minimal angle of resolution (logMAR) visual acuity (VA) at that time (1.39 +/- 0.67) was not significantly changed from that before surgery (logMAR, 1.31 +/- 0.66) in 25 eyes with age-related macular degeneration (AMD). However, at 5-year follow-up, foveal retinal pigment epithelium atrophy increased (18 eyes; 72%), and final mean logMAR VA (1.88 +/- 0.76) was significantly lower (P < .01). Five eyes with myopic CNV maintained their VA from before operation (mean logMAR, 0.88 +/- 0.35) until final follow-up (mean logMAR, 0.73 +/- 0.31). The final VA was significantly better in myopic CNV than in exudative age-related macular degeneration on multiple regression analysis (P = .019).
  
  
  CONCLUSIONS
  Long-term follow-up of full macular translocation showed that the final VA was poor in age-related macular degeneration, but relatively better in myopic CNV.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. y-yoshi@nagasaki-u.ac.jp
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Yamada
authors.forename: Noritake
authors.initials: N
authors.lastname: Miyamura
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Suzuma
authors.forename: Takashi
authors.initials: T
authors.lastname: Kitaoka
mesh_terms: D000368:Aged; D001284:Atrophy; D020256:Choroidal Neovascularization / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D008266:Macula Lutea / Q000637:transplantation*; D008268:Macular Degeneration / Q000150:complications; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications; D018918:Phacoemulsification; D011183:Postoperative Complications; D055213:Retinal Pigment Epithelium / Q000473:pathology; D012189:Retrospective Studies; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils