title: [Fatal poisoning with the local anesthetic bupivacaine].
abstract: Lethal concentration of bupivacaine was determined based on the examination of a case of poisoning with this local anesthetic agent taken at a dose 5 times the normal value. This study is of special interest taking into consideration the lack of data on toxic and lethal doses of bupivacaine in splanchnic organs and tissues in the literature.
authors.forename: A V
authors.initials: AV
authors.lastname: Kirichek
authors.forename: L A
authors.initials: LA
authors.lastname: Shmarov
authors.forename: N A
authors.initials: NA
authors.lastname: Shatrovskiĭ
authors.forename: E M
authors.initials: EM
authors.lastname: Salomatin
authors.forename: E A
authors.initials: EA
authors.lastname: Simonov
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage / Q000302:isolation & purification / Q000493:pharmacokinetics / Q000506:poisoning* / Q000627:therapeutic use; D002045:Bupivacaine / Q000008:administration & dosage / Q000302:isolation & purification / Q000493:pharmacokinetics / Q000506:poisoning* / Q000627:therapeutic use; D017809:Fatal Outcome; D053593:Forensic Toxicology; D006801:Humans; D008297:Male; D008508:Medication Errors; D009928:Organ Specificity; D011041:Poisoning / Q000175:diagnosis; D014018:Tissue Distribution
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine