title: Is race a risk factor for the development of renal artery stenosis?
abstract: Atherosclerotic renal artery disease is a common cause of hypertension and chronic kidney disease that may progress into end stage renal failure if not diagnosed and treated early. Renal artery stenosis (RAS) has been shown to be an independent risk factor for mortality in patients with coronary artery disease. We sought to determine whether race is an independent risk factor for developing RAS. A retrospective study was conducted including 324 patients with resistant hypertension who underwent renal angiography with or without coronary angiography. In univariate analysis, Caucasian race was associated with significant risk of RAS (OR = 2.3, P = .01). However, this association was no longer significant after correcting for additional clinical variables in a multivariate model (OR = 1.5, P = .07). There was a strong association between smoking and RAS (OR 2.0, P = .02). We conclude that traditional risk factors, especially smoking, rather than race, are the most important predictors of RAS development.
authors.affiliation: Division of Cardiology, Providence Hospital and Medical Center, Southfield, MI 48075, USA.
authors.forename: Ayad
authors.initials: A
authors.lastname: Jazrawi
authors.forename: Saba
authors.initials: S
authors.lastname: Darda
authors.forename: Peter
authors.initials: P
authors.lastname: Burke
authors.forename: Marcos
authors.initials: M
authors.lastname: Daccarett
authors.forename: Josef
authors.initials: J
authors.lastname: Stehlik
authors.forename: Shukri
authors.initials: S
authors.lastname: David
authors.forename: Marcel
authors.initials: M
authors.lastname: Zughaib