Fast synthesis of N-acylhydrazones employing a microwave assisted neat protocol.
A variety of N-acylhydrazones were synthesized under microwave irradiation within 2.5-10 min, starting from benzo, salicyloyl, and isonicotinic hydrazides. The protocol developed employs microwave irradiation in the absence of solvents and catalysts, leading to high yields. The results are reproducible in a 500 mg to 5 g scale.
Andrade
Marta M
MM
REQUIMTE, CQFB, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal. marta.andrade@dq.fct.unl.pt
Barros
Maria Teresa
MT
D006835:Hydrazones / Q000138:chemical synthesis*; D006860:Hydrogen Bonding; D008872:Microwaves; D015203:Reproducibility of Results
D006835:Hydrazones