title: Diagnostic value of 3D fast low-angle shot dynamic MRI of breast papillomas.
abstract: OBJECTIVE
  To evaluate the value of breast MRI in analysis of papillomas of the breast.
  
  
  METHODS
  From 1996 to 2004, 94 patients underwent surgery due to papillomas of the breast. Among them, 21 patients underwent 3D fast low angle shot (FLASH) dynamic breast MRI. Eight masses were palpable and 11 of 21 patients had nipple discharge. Two radiologists indifferently analyzed the location, size of the lesions and shape, margin of the masses, multiplicity and ductal relation. The MRI findings were categorized according to breast imaging reporting and data system (BI-RADS) lexicon. The amount and pattern of enhancement and associated findings were also evaluated according to BI-RADS. We then compared the MRI findings with galactography, mammography and breast ultrasonography (US) and examined histopathologic correlation.
  
  
  RESULTS
  On breast MRI, the lesion size was 0.4-1.59 cm, and 18 patients showed subareolar location. On 4.25 cm (mean 1.54) dynamic enhanced images, imaging findings showed mass (n = 10), intracystic mass (n = 3), focus (n = 5), ductal enhancement (n = 2), and segmental enhancement (n = 1). In cases of the masses, the shapes of the masses were round (n = 4), lobulated (n = 3), and irregular (n = 6), and margins were circumscribed (n = 6), microlobulated (n = 5), and indistinct (n = 2). The enhancement patterns were homogeneous enhancement (n = 7), heterogeneous (n = 3) or rim enhancement (n = 3).
  
  
  CONCLUSIONS
  The contrast enhanced dynamic breast MRI was highly sensitive for diagnosis of breast papillomas. MRI could play a key role in the pre-operative work-up for multiple papillomas and papillomatosis.
authors.affiliation: Department of Radiology, The Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. ejsonrd@yuhs.ac
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Son
authors.forename: Eun-Kyung
authors.initials: EK
authors.lastname: Kim
authors.forename: Jeong-Ah
authors.initials: JA
authors.lastname: Kim
authors.forename: Jin Young
authors.initials: JY
authors.lastname: Kwak
authors.forename: Joon
authors.initials: J
authors.lastname: Jeong
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D018300:Papilloma, Intraductal / Q000175:diagnosis*; D012680:Sensitivity and Specificity