title: Safety of early exercise training after elective coronary stenting in patients with stable coronary artery disease.
abstract: BACKGROUND
  Early exercise after coronary stenting is considered to have a risk of stent thrombosis (ST). We investigate the safety of submaximal exercise training based on the Borg scale from the next day after coronary stenting.
  
  
  METHODS
  We enrolled 2351 patients who underwent successful coronary stenting. They were divided into early exercise training (EET) group (n=865) and control group (n=1486). Submaximal exercise training based on the Borg scale was performed on the next day after coronary stenting and same degree exercise was continued more than two times a week after discharge. Primary endpoint was the incidence of ST. Secondary endpoint was major adverse cardiovascular event (death, myocardial infarction, and stroke), incidence of postoperative complications, and rate of exercise continuation.
  
  
  RESULTS
  Exercise training was performed in 800 (92.5%) patients. No serious complication developed during and after exercise. Clinical follow-up data were obtained in 99% patients. At 30 days, there was no significant difference in the incidence of ST (0.58 vs. 0.47%, P=0.73), major adverse cardiovascular event (1.4 vs. 1.3%, P=0.72), and complication rate (6.9 vs. 7.3%, P=0.72). No exercise-related ST was found in either group. The rate of exercise continuation was significantly higher in the EET group (49.3 vs. 28.3%, P<0.001).
  
  
  CONCLUSIONS
  EET up to submaximal level based on the Borg scale from the day after elective coronary stenting does not increase the incidence of ST or postoperative complications.
authors.affiliation: Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan. sogacchy@yahoo.co.jp
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Soga
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Yokoi
authors.forename: Kenji
authors.initials: K
authors.lastname: Ando
authors.forename: Shinichi
authors.initials: S
authors.lastname: Shirai
authors.forename: Koyu
authors.initials: K
authors.lastname: Sakai
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Kondo
authors.forename: Masahiko
authors.initials: M
authors.lastname: Goya
authors.forename: Masashi
authors.initials: M
authors.lastname: Iwabuchi
authors.forename: Masakiyo
authors.initials: M
authors.lastname: Nobuyoshi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality; D016009:Chi-Square Distribution; D003324:Coronary Artery Disease / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D005081:Exercise Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D016016:Proportional Hazards Models; D011446:Prospective Studies; D020127:Recovery of Function; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D020521:Stroke / Q000209:etiology; D013927:Thrombosis / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology; D013997:Time Factors; D016896:Treatment Outcome