title: Cytogenetic effects of exposure to 2.3 GHz radiofrequency radiation on human lymphocytes in vitro.
abstract: BACKGROUND
  No previous in vitro studies have tested radio frequency radiation for at least one full cell cycle in culture. The aim was to test if exposure used in mobile phones and wireless network technologies would induce DNA damage in cultured human lymphocytes with and without a known clastogen.
  
  
  METHODS
  Lymphocytes from six donors were exposed to 2.3 GHz, 10 W/m(2) continuous waves, or 2.3 GHz, 10 W/m(2) pulsed waves (200 Hz pulse frequency, 50% duty cycle). Mitomycin C was added to half of the cultures. DNA synthesis and repair were inhibited in one experiment.
  
  
  RESULTS
  No statistically significant differences were observed between control and exposed cultures. A weak trend for more chromosomal damage with the interaction of pulsed fields with mitomycin C compared to a constant field was observed.
  
  
  CONCLUSIONS
  Exposure during the whole cell cycle in inhibited cultures did not resulted in significant differences in chromosomal aberrations as compared to controls.
authors.affiliation: Department of Research and Development, The Cancer Center, Oslo University Hospital, Ulleval, 0407 Oslo, Norway.
authors.forename: Inger-Lise
authors.initials: IL
authors.lastname: Hansteen
authors.forename: Kjell O
authors.initials: KO
authors.lastname: Clausen
authors.forename: Vera
authors.initials: V
authors.lastname: Haugan
authors.forename: Marit
authors.initials: M
authors.lastname: Svendsen
authors.forename: Martin V
authors.initials: MV
authors.lastname: Svendsen
authors.forename: Jan G
authors.initials: JG
authors.lastname: Eriksen
authors.forename: Rolf
authors.initials: R
authors.lastname: Skiaker
authors.forename: Egil
authors.initials: E
authors.lastname: Hauger
authors.forename: Lars
authors.initials: L
authors.lastname: Lågeide
authors.forename: Arnt I
authors.initials: AI
authors.lastname: Vistnes
authors.forename: Elin H
authors.initials: EH
authors.lastname: Kure
mesh_terms: D000328:Adult; D040421:Cell Phone; D002478:Cells, Cultured; D003582:Cytogenetics; D004249:DNA Damage; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects