title: A novel body weight-loss promoting oil prepared with vegetable protein.
abstract: It has been reported that oil thermally processed with wheat gluten (gluten oil) exhibited safe weight-loss promoting effects in animal experiments. However, as the oil has a high color index, and its chemical properties and smell differ from those of fresh oil, it is uncertain if the oil will find market acceptance. In order to resolve the issue, frying oil was heated with soybean protein under reduced pressure (soybean protein oil), resulting in a product with an appearance, chemical properties and smell comparable to those of fresh oil. This improved oil was mixed (7 wt%) with powdered AIN93G no fat, defined standard diet and fed to 10-week-old Wistar rats ad libitum. The experimental rats grew normally, ingesting the same amount as that of the control rats; however, there was a negative correlation between body weight increases and fecal weight increases. After the 12-week feeding period, all the rats were sacrificed to obtain blood and organs. In the experimental group, liver weight, retroperitoneal fat tissue weight and serum triacylglycerol (TG) levels decreased significantly. Aspartate aminotransferase (AST), alanine aminotransferase (ALT), and histological analysis supported the safety of the improved oil. In conclusion, it was found that soybean protein oil inhibited body weight increases without any adverse effects in animal experiments. The oil holds promise as a novel dieting oil that steadily decreases body weight at an appropriate rate.
authors.affiliation: Department of Nutritional Physiology, Faculty of Nutrition, Kobe-Gakuin University, Kobe, 651-2180, Japan. totani@nutr.kobegakuin.ac.jp
authors.forename: Nagao
authors.initials: N
authors.lastname: Totani
authors.forename: Akira
authors.initials: A
authors.lastname: Morita
authors.forename: Maki
authors.initials: M
authors.lastname: Nishinaka
authors.forename: Sayuri
authors.initials: S
authors.lastname: Tateishi
authors.forename: Haruyasu
authors.initials: H
authors.lastname: Kida
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D004041:Dietary Fats / Q000494:pharmacology*; D008297:Male; D014674:Plant Proteins, Dietary / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012015:Reference Standards; D013024:Soybean Oil / Q000494:pharmacology*; D013025:Glycine max / Q000737:chemistry; D015431:Weight Loss / Q000187:drug effects*
chemical_list: D004041:Dietary Fats; D014674:Plant Proteins, Dietary; D013024:Soybean Oil; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase