title: Trichilemmal carcinoma of the upper eyelid: a case report.
abstract: We report a very rare case of trichilemmal carcinoma (TLC) involving the upper eyelid. To the best of our knowledge, this is the first report of trichilemmal carcinoma of the upper eyelid in Korea. A 51-year-old man presented to our hospital complaining of a bloody discharge from his left upper eyelid. He had a soft and lobulated mass on the palpebral conjunctiva. An incisional biopsy revealed trabecular growth of tumor cells with clear cytoplasm, prominent nucleoli, frequent mitoses, and foci of trichilemmal keratinization. Immunohistochemically, the lesion was positive for p53 and negative for CD 34. A diagnosis of TLC was made, and total excision of the mass and reconstruction of the eyelid were performed. Trichilemmal carcinoma is a rare malignant tumor, though it appears to be an indolent neoplasm with no metastatic potential. The treatment of choice for trichilemmal carcinoma of the eyelid is complete excision with tumor-free margins due to the locally invasive nature of the lesion.
authors.affiliation: Department of Ophthalmology, Hanyang University School of Medicine, Seoul, Korea.
authors.forename: Ju Hyang
authors.initials: JH
authors.lastname: Lee
authors.forename: Yong Woon
authors.initials: YW
authors.lastname: Shin
authors.forename: Young Ha
authors.initials: YH
authors.lastname: Oh
authors.forename: Yoon Jung
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D018280:Carcinoma, Skin Appendage / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006197:Hair; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery