title: Spontaneous multivessel coronary artery dissection.
abstract: As opposed to iatrogenic coronary dissection, spontaneous dissection is an extremely rare clinical condition. Typically seen in a single coronary vessel of peripartum women presenting with acute coronary syndrome, there are isolated case reports of men presenting multivessel involvement for this life-threatening condition. We describe a 54-year-old male with a history of diabetes, hypertension and methamphetamine abuse who presented to the emergency after a brief, witnessed cardiac arrest. Admission ECG revealed sinus tachycardia with inferior Q waves. He was found to have frequent runs of non-sustained ventricular tachycardia and minimal troponin-T elevation. His 2-D echocardiogram showed apical akinesis with an ejection fraction of 50%. Cardiac catheterization revealed a patent left main artery with a spontaneous dissection involving the mid to distal LAD artery, as well as large first diagonal branch with proximal dissection. His dominant RCA also showed long spontaneous dissection extending from proximal to distal vessel, along with distal focal 90% atherosclerotic lesion. Ramus intermedius and left circumflex vessels were free of disease. The patient underwent a 2-vessel coronary artery bypass grafting (CABG) with excellent outcome. Although cocaine abuse has been known to be associated with spontaneous dissection, this is the first reported case of a methamphetamine user presenting with multivessel coronary dissection.
authors.affiliation: Department of Medicine, St. John Hospital and Medical Center, 22101 Moross Road, 2nd Floor VEP, Cardiac Cath Lab, Detroit, MI 48236, USA. manreet.kanwar@stjohn.org
authors.forename: Manreet
authors.initials: M
authors.lastname: Kanwar
authors.forename: Nikita
authors.initials: N
authors.lastname: Gill
mesh_terms: D000784:Aortic Dissection / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000601:surgery; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000601:surgery; D003331:Coronary Vessels; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000009:adverse effects; D008875:Middle Aged; D012422:Rupture, Spontaneous; D019966:Substance-Related Disorders / Q000150:complications; D016896:Treatment Outcome
chemical_list: D008694:Methamphetamine