title: [Transcranial sonothrombolysis].
abstract: Transcranial ultrasonic diagnostic equipment has been approved to enhance the thrombolytic effect of IVrt-PA. Moreover, transcranial sonothrombolysis with low frequency ultrasound has a great advantage in lytic effect of IVrt-PA. It is remarkable to choose a optimal ultrasonic condition for transcranial sonothrombolysis. We are developing a new transcranial targeting Low Frequency Ultrasonic Thrombolysis system (TCT-LoFUT). This system is anticipated to be a useful therapeutic equipment to realize a early recanalization in the acute ischemic stroke treatment.
authors.affiliation: ME Lab. Research Center for Medical Science, The Jikei University School of Medicine.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furuhata
mesh_terms: D000208:Acute Disease; D000818:Animals; D006801:Humans; D007262:Infusions, Intravenous; D051381:Rats; D011994:Recombinant Proteins; D020521:Stroke / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000295:instrumentation / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator