title: Short-term complications of wide-lumen stapled anastomosis after ileocolic resection for Crohn's disease: who is at risk?
abstract: OBJECTIVE
  There is growing evidence that stapled anastomoses are similarly effective compared to hand-sewn anastomoses in Crohn's patients. This study was designed to assess safety and limitations of wide-lumen stapled ileocolic anastomoses.
  
  
  METHODS
  All patients with ileocolic resections for Crohn's disease perfomed between 1998 and 2006 were studied. A stapled anastomosis was constructed whenever possible. Potential risk factors for postoperative complications were recorded, retrospectively. Univariate and multivariate analyses were performed.
  
  
  RESULTS
  In 209 out of 220 cases (95%, 132 primary operations) stapled anastomoses were performed. Eleven patients underwent a hand-sewn anastomosis owing to massive bowel dilatation (n = 7) or increased wall thickness (n = 4). There were 10 major (4.5%; surgical: 8, medical: 2) complications including two anastomotic leaks and one anastomotic bleed (all from stapled anastomoses) and one death not related to the anastomosis. Minor complications occurred in 25 patients. In multivariate analysis, major surgical postoperative complications were significantly associated with a low level of albumin (P = 0.0113) and previous resections for Crohn's disease (P = 0.0144).
  
  
  CONCLUSIONS
  Stapled ileocolic anastomosis was safe in the majority of Crohn's patients. The most important limitation was technical impracticability. A low level of albumin and a history of previous resection increased the risk of postoperative complications.
authors.affiliation: Department of General Surgery, Medical University of Vienna, Austria.
authors.forename: S
authors.initials: S
authors.lastname: Riss
authors.forename: C
authors.initials: C
authors.lastname: Bittermann
authors.forename: S
authors.initials: S
authors.lastname: Zandl
authors.forename: I
authors.initials: I
authors.lastname: Kristo
authors.forename: A
authors.initials: A
authors.lastname: Stift
authors.forename: P
authors.initials: P
authors.lastname: Papay
authors.forename: H
authors.initials: H
authors.lastname: Vogelsang
authors.forename: M
authors.initials: M
authors.lastname: Mittlböck
authors.forename: F
authors.initials: F
authors.lastname: Herbst
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000009:adverse effects*; D057868:Anastomotic Leak / Q000209:etiology*; D003106:Colon / Q000601:surgery*; D003424:Crohn Disease / Q000601:surgery; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D034141:Hypoalbuminemia / Q000150:complications; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012086:Reoperation / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D017792:Surgical Stapling / Q000009:adverse effects* / Q000379:methods; D055815:Young Adult