title: Analogues of distamycin--synthesis and biological evaluation of new aromatic oligopeptides, potential anticancer agents.
abstract: Six new aromatic oligopeptides were synthesized and evaluated for their activity in the standard cell line of the mammalian tumor MCF-7 as well as in a cell-free system employing the topoisomerase I/II inhibition assay.
authors.affiliation: Department of Organic Chemistry, Medical University, 2A Mickiewicza, 15-222 Białystok, Poland. Danuta.Drozdowska@umwb.edu.pl
authors.forename: Danuta
authors.initials: D
authors.lastname: Drozdowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Rusak
authors.forename: Tomasz
authors.initials: T
authors.lastname: Bielawski
authors.forename: Krystyna
authors.initials: K
authors.lastname: Midura-Nowaczek
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D045744:Cell Line, Tumor; D004214:Distamycins / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D059003:Topoisomerase Inhibitors
chemical_list: D000970:Antineoplastic Agents; D004214:Distamycins; D059003:Topoisomerase Inhibitors