Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital.
The case of a patient with recurrent esthesioneuroblastoma complicated by ectopic adrenocorticotropic hormone production is presented, including the workup and management of this uncommon complication of an uncommon disease.
Mintzer
David M
DM
230 W. Washington Square, 2nd Floor, Philadelphia, Pennsylvania 19106, USA. mintzerd@pahosp.com
Zheng
Sarah
S
Nagamine
Michiko
M
Newman
Jason
J
Benito
Maria
M
D000182:ACTH Syndrome, Ectopic / Q000188:drug therapy / Q000209:etiology*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003606:Dacarbazine / Q000031:analogs & derivatives / Q000627:therapeutic use; D018304:Esthesioneuroblastoma, Olfactory / Q000150:complications / Q000378:metabolism* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000627:therapeutic use; D007150:Immunohistochemistry; D007654:Ketoconazole / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D009669:Nose Neoplasms / Q000150:complications / Q000378:metabolism* / Q000473:pathology / Q000628:therapy*; D015282:Octreotide / Q000627:therapeutic use; D000077204:Temozolomide
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D018906:Antineoplastic Agents, Alkylating; D018931:Antineoplastic Agents, Hormonal; D003606:Dacarbazine; D000324:Adrenocorticotropic Hormone; D007654:Ketoconazole; D015282:Octreotide; D006854:Hydrocortisone; D000077204:Temozolomide