title: On the physical meaning of the isothermal titration calorimetry measurements in calorimeters with full cells.
abstract: We have performed a detailed study of the thermodynamics of the titration process in an isothermal titration calorimeter with full cells. We show that the relationship between the enthalpy and the heat measured is better described in terms of the equation Delta H = W(inj) + Q (where W(inj) is the work necessary to carry out the titration) than in terms of DeltaH = Q. Moreover, we show that the heat of interaction between two components is related to the partial enthalpy of interaction at infinite dilution of the titrant component, as well as to its partial volume of interaction at infinite dilution.
authors.affiliation: Laboratoire de Thermodynamique des Solutions et des Polymères Université Blaise Pascal, 24, Avenue des Landais, Clermont Ferrand, 63177 Aubière Cedex, France.
authors.forename: Jean-Pierre E
authors.initials: JE
authors.lastname: Grolier
authors.affiliation: Research and Development Branch on Flow Assurance, Mexican Institute of Petroleum, Eje Central Lazaro Cardenas 152, Col. San Bartolo Atepehuacan, Mexico City 07730, Mexico.
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Del Río
mesh_terms: D002151:Calorimetry / Q000295:instrumentation / Q000379:methods*; D013816:Thermodynamics