title: Antibiotic prophylaxis in otolaryngologic surgery.
abstract: Since the beginning of the 80s, numerous clinical trials have shown a significant reduction in the incidence of infections in clean-contaminated upper respiratory tract surgery, due to perioperative use of antibiotics; however, there is no consensus about the best antibiotic protocol. Moreover, there are no universally accepted guidelines about flap reconstructive procedures. In otological and rhinological surgery, tonsillectomy, cochlear implant and laryngo-pharyngeal laser surgery, the use of antibiotics frequently depends on institutional or personal preferences rather than the evidence available. We reviewed clinical trials on different otorhinolaryngological procedures, assessing choice of antibiotic, length of treatment and administration route. There are no clinical trials for laryngo-pharyngeal laser surgery. Nor are there clinical trials on implant cochlear surgery or neurosurgical clean-contaminated procedures, but in these circumstances, antibiotic prophylaxis is recommended.
authors.affiliation: Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Asturias, España. sergioobeso@yahoo.es
authors.forename: Sergio
authors.initials: S
authors.lastname: Obeso
authors.forename: Juan P
authors.initials: JP
authors.lastname: Rodrigo
authors.forename: Rafael
authors.initials: R
authors.lastname: Sánchez
authors.forename: Fernando
authors.initials: F
authors.lastname: López
authors.forename: Juan P
authors.initials: JP
authors.lastname: Díaz
authors.forename: Carlos
authors.initials: C
authors.lastname: Suárez
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D004311:Double-Blind Method; D004333:Drug Administration Routes; D004334:Drug Administration Schedule; D019317:Evidence-Based Medicine; D006801:Humans; D053685:Laser Therapy; D009305:Nasopharynx / Q000382:microbiology; D013517:Otorhinolaryngologic Surgical Procedures; D017410:Practice Guidelines as Topic; D011446:Prospective Studies; D012189:Retrospective Studies; D016037:Single-Blind Method; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents