title: Aporphine and bisaporphine alkaloids from Aristolochia lagesiana var. intermedia.
abstract: Corydines, isocorydines, and analogous aporphine alkaloids were isolated from the leaves of Aristolochia lagesiana var. intermedia, together with three bisaporphine salts (lagesianines B-D). Their structures were determined by chemical derivatizations and spectroscopic analyses. Lagesianines B and C are the first examples of N-CH(2)-N' and C-2-O-C-1' linked dimeric aporphine alkaloids, respectively, while the monomeric units of lagesianine D, which has a carbon skeleton, are linked through C-7-C-5'via an ethane-1,2-diol group (C-7-CHOHCHOH-C-5').
authors.affiliation: Instituto de Química, São Paulo State University, UNESP, C.P. 355, 14801-970 Araraquara, SP, Brazil.
authors.forename: Marcia L R
authors.initials: ML
authors.lastname: Ferreira
authors.forename: Inara C
authors.initials: IC
authors.lastname: de Pascoli
authors.forename: Isabele R
authors.initials: IR
authors.lastname: Nascimento
authors.forename: Julio
authors.initials: J
authors.lastname: Zukerman-Schpector
authors.forename: Lucia M X
authors.initials: LM
authors.lastname: Lopes
mesh_terms: D001060:Aporphines / Q000737:chemistry* / Q000302:isolation & purification*; D030022:Aristolochia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
chemical_list: D001060:Aporphines; C081279:aporphine