title: Pneumocystis colonization in older adults and diagnostic yield of single versus paired noninvasive respiratory sampling.
abstract: The presence of Pneumocystis was assessed in oropharyngeal wash specimens from 110 adults (median age, 76 years; age range, 69-95 years), 66 of whom had a paired nasal swab specimen. Pneumocystis jirovecii DNA was detected in 12.8% of oropharyngeal wash specimens, and the frequency increased to 21.5% in paired specimens. Pneumocystis colonization is prevalent in older adults. Double noninvasive sampling increases the diagnostic yield.
authors.affiliation: Programa de Microbiología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, and 2Consultorio Agustín Cruz Melo, Independencia, Santiago, Chile. svargas@terra.cl
authors.forename: Sergio L
authors.initials: SL
authors.lastname: Vargas
authors.forename: Patricia
authors.initials: P
authors.lastname: Pizarro
authors.forename: Mónica
authors.initials: M
authors.lastname: López-Vieyra
authors.forename: Patricia
authors.initials: P
authors.lastname: Neira-Avilés
authors.forename: Rebeca
authors.initials: R
authors.lastname: Bustamante
authors.forename: Carolina A
authors.initials: CA
authors.lastname: Ponce
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D004271:DNA, Fungal / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000382:microbiology; D009960:Oropharynx / Q000382:microbiology; D016720:Pneumocystis Infections / Q000453:epidemiology* / Q000382:microbiology*; D045363:Pneumocystis carinii / Q000302:isolation & purification*; D015995:Prevalence
chemical_list: D004271:DNA, Fungal