[Herpesvirus type 8 and its implication in human pathology].
Herpesvirus type 8 or Kaposi's sarcoma-associated virus has been recently discovered and it is an etiologic agent of several known diseases. It has common features that link it with other representatives of the family Herpesviridae: similar structural elements and genomic organization, and the common mechanisms of replication. Nevertheless, this virus has a number of unique features that make it an interesting matter for investigations and currently central in modern medicine and biology. This overview is to draw attention to this representative of herpesviruses and to outline some epidemiological, pathogenetic, and molecular aspects of this problem.
Potapova
L A
LA
Kosiakova
N P
NP
Makhneva
N V
NV
Mezentseva
M V
MV
D015870:Gene Expression; D014644:Genetic Variation; D016679:Genome, Viral / Q000235:genetics; D014943:Global Health; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000821:virology*; D019288:Herpesvirus 8, Human / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D006801:Humans; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000821:virology*; D017735:Virus Latency; D014779:Virus Replication