title: [A case of recurrence gastric cancer patient who was post operated and multi drug chemotherapy was effective for administration of S-1 and docetaxel combination therapy].
abstract: Recently, chemotherapy against gastric cancer has been diversified with an appearance of new agents such as S-1, capecitabine, CPT-11, oxaliplatin, paclitaxel and docetaxel. But a prognosis of advanced or recurrent gastric cancer patient, who was failure of first- and second-line chemotherapy, was poor. We reported that a case of recurrence gastric cancer patient who was post operated and multi drug chemotherapy was effective for administration of S-1 and docetaxel combination therapy. A case was a 50-year-old man. He underwent distal gastrectomy and administered of multi anticancer drugs until about eight years after operation. But multi lung and liver and lymph-node metastases were appeared. We administered S-1 and docetaxel combination chemotherapy. After two courses, multi metastatic lesions were reduced in size, and tumor markers were decreased. The same combination therapy was administered for six courses, but metastatic lesions were increased again. At one hundred four months after the operation, he died in the palliative care unit.
authors.affiliation: Department of Surgery, Tokyo Metropolitan Toshima Hospital.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Toshiya
authors.initials: T
authors.lastname: Ohara
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Kenichirou
authors.initials: K
authors.lastname: Hataji
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Andou
authors.forename: Shikofumi
authors.initials: S
authors.lastname: Tei
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000077143:Docetaxel; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid