title: Is PRP useful in alveolar cleft reconstruction? Platelet-rich plasma in secondary alveoloplasty.
abstract: OBJECTIVE
  Cleft lip and palate is a congenital facial malformation with an established treatment protocol. Mixed dentition period is the best moment for correct maxillary bone defect with an alveoloplasty. The aim of this surgical procedure is to facilitate dental eruption, re-establish maxillary arch, close any oro-nasal communication, give support to nasal ala, and in some cases allow dental rehabilitation with osteointegrated implants.
  
  
  METHODS
  Twenty cleft patients who underwent secondary alveoloplasty were included. In 10 of them autogenous bone graft were used and in other 10 autogenous bone and platelet-rich plasma (PRP) obtained from autogenous blood. Bone formation was compared by digital orthopantomography made on immediate post-operatory and 3 and 6 months after the surgery.
  
  
  RESULTS
  No significant differences were found between both therapeutic groups on bone regeneration.
  
  
  CONCLUSIONS
  We do not find justified the use of PRP for alveoloplasty in cleft patients' treatment protocol.
authors.affiliation: Servicio de Cirugia Maxilofacial, Complexo Hospitalario A Coruña, As Xubias 84, 15006, A Coruña, Spain. ramon.luaces.rey@sergas.es
authors.forename: Ramon
authors.initials: R
authors.lastname: Luaces-Rey
authors.forename: Jorge
authors.initials: J
authors.lastname: Arenaz-Búa
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Lopez-Cedrún-Cembranos
authors.forename: Susana
authors.initials: S
authors.lastname: Herrero-Patiño
authors.forename: Sheyla
authors.initials: S
authors.lastname: Sironvalle-Soliva
authors.forename: Emma
authors.initials: E
authors.lastname: Iglesias-Candal
authors.forename: María
authors.initials: M
authors.lastname: Pombo-Castro
mesh_terms: D000543:Alveoloplasty / Q000379:methods; D001861:Bone Regeneration; D016025:Bone Transplantation; D002648:Child; D002971:Cleft Lip / Q000601:surgery*; D002972:Cleft Palate / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D053657:Platelet-Rich Plasma