[Terpenoids from Euphorbia antiquorum L.].
To study the chemical constituents of Euphorbia antiquorum L., the constituents were isolated with normal-phase and reverse-phase silica gel column chromatography and their structures were elucidated on the basis of spectroscopic data. Seven terpenoids were obtained from EtOAc extract of E. antiquoru L. They were identified as antiquorine A (1), antiquorine B (2), ent-13S-hydroxy-16-atisene-3,14-dione (3), taraxerol (4), 3beta-hydroxy-25,26,27-trisnorcycloart-24-oic acid (5), 9beta,19-cyclolanostan-3beta-ol (6) and psi-taraxastane-3,20-diol (7) by spectral analysis. Compounds 1-3 are diterpenoids, which belonged to abietane, ent-kaurane and atisane respectively. Among them, compounds 1 and 2 are new compounds. Compounds 4-7 are triterpenoids, and compound 5 is a degraded cycloartane triterpenoid which is a new natural product. Compound 7 was isolated from this plant for the first time. It demonstrated that the chemical structures of constituents in this plant were diverse.
Chen
Yu
Y
College of Chemistry and Material Sciences, South Central University for Nationalities, Wuhan 430074, China.
Tian
Xue-Jun
XJ
Li
Yun-Fang
YF
Yang
Guang-Zhong
GZ
D028481:Euphorbia / Q000737:chemistry*; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
C573656:3beta-hydroxy-25,26,27-trisnorcycloart-24-oic acid; D013729:Terpenes; C573654:antiquorine A; C573655:antiquorine B; D009828:Oleanolic Acid; C005802:taraxerol