title: Early assessment of visual function in preterm infants: how early is early?
abstract: BACKGROUND
  Several studies reported on various aspects of visual function at term age and in the first months after birth but less has been reported in preterm infants before they reach termequivalent age.
  
  
  OBJECTIVE
  To assess the suitability of a battery of tests of visual function for use in infants born at <33weeks gestation (GA) and assessed before 34weeks post-menstrual age (PMA); to evaluate the distribution of the findings according to GA, and to compare the data with those previously published on preterm infants assessed at 35weeks PMA.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Sixty-four preterm infants with a GA <33weeks were studied.
  
  
  METHODS
  We used a battery of visual function tests previously validated at 35 and 40weeks PMA in low-risk preterm infants. All the infants in this current study underwent the same assessment before 34weeks PMA.
  
  
  RESULTS
  Before 31weeks PMA most infants could not be reliably assessed because of clinical instability, whilst after 31weeks PMA most infants could be assessed and they showed progressive maturation in their responses with PMA. Some items (spontaneous ocular motility, horizontal tracking, tracking a coloured stimulus, and ocular fixation) showed similar results at 32-33weeks PMA to those found in low-risk preterm at 35weeks PMA. Ocular movements to a target and arc tracking were the items with the most immature responses.
  
  
  CONCLUSIONS
  Our results provide further evidence that a structured assessment of visual function can be used in clinical routine and for research purposes in infants as young as 31weeks PMA.
authors.affiliation: Paediatric Neurology Unit, Catholic University, Rome, Italy. daniricciola@libero.it <daniricciola@libero.it>
authors.forename: Daniela
authors.initials: D
authors.lastname: Ricci
authors.forename: Domenico M
authors.initials: DM
authors.lastname: Romeo
authors.forename: Francesca
authors.initials: F
authors.lastname: Serrao
authors.forename: Francesca
authors.initials: F
authors.lastname: Gallini
authors.forename: Daniela
authors.initials: D
authors.lastname: Leone
authors.forename: Mariagrazia
authors.initials: M
authors.lastname: Longo
authors.forename: Emilio
authors.initials: E
authors.lastname: Albamonte
authors.forename: Mario G
authors.initials: MG
authors.lastname: Romeo
authors.forename: Domenico
authors.initials: D
authors.lastname: Mazzone
authors.forename: Costantino
authors.initials: C
authors.lastname: Romagnoli
authors.forename: Frances
authors.initials: F
authors.lastname: Cowan
authors.forename: Eugenio
authors.initials: E
authors.lastname: Mercuri
mesh_terms: D000367:Age Factors; D002657:Child Development / Q000502:physiology*; D003430:Cross-Sectional Studies; D005133:Eye Movements / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D014787:Vision Tests / Q000379:methods*; D014785:Vision, Ocular / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology