[A case of hepatitis B-related multiple hepatocellular carcinomas, most of which lead to necrosis possibly due to the implantation of an arterial infusion catheter].
The patient was a 59-year-old male with chronic hepatitis type B. He was diagnosed as having multiple hepatocellular carcinomas (HCCs), most of which showed hypervascular features on contrast-enhanced CT scan. He underwent the implantation of a 5-french catheter by" GDA coil method" for hepatic arterial infusion of chemotherapy. After the implantation, he suffered from high fever with a sharp elevation in transaminase levels. Since his liver function gradually deteriorated, he was not able to receive hepatic arterial infusion of chemotherapy. However, three weeks after catheter implantation, most of the tumors were no longer enhanced on dynamic CT scan, suggesting a loss of tumor vascularity, ie, induction of tumor necrosis. It was speculated that necrosis of the tumors was caused by the reduction of hepatic arterial blood flow due to the catheter placement.
Kuzuya
Teiji
T
Department of Gastroenterology, Nagoya Kyoritsu Hospital, Nagoya University Graduate School of Medicine.
Takeda
Kinichi
K
Utsunomiya
Setsuo
S
Taga
Masahiro
M
Kawata
Noboru
N
Ikeda
Takashi
T
Imai
Norihiro
N
Mizutani
Yoshitaka
Y
Hirose
Ken
K
Ishikawa
Tetsuya
T
Katano
Yoshiaki
Y
Goto
Hidemi
H
D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis