title: Acute thrombosis of an abdominal aortic aneurysm followed by delayed rupture associated with bacterial infection.
abstract: Sudden thrombosis of an abdominal aortic aneurysm (AAA) is distinctly rare and is associated with up to 50% mortality. Almost equally rare is infection of a preexisting AAA. We report an extremely unusual case of an AAA that thrombosed leading to acute limb ischemia. This was followed several months later by a delayed rupture of the thrombosed AAA associated with an Escherichia coli infection. We suspect the aortic thrombus was hematogenously seeded by a urinary tract infection. A review of the literature revealed that bacterial infection of a previously thrombosed AAA, leading to a delayed rupture, has not been previously reported.
authors.affiliation: David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. cdevirgilio@labiomed.org
authors.forename: Brandon M
authors.initials: BM
authors.lastname: Ishaque
authors.forename: Phillip S
authors.initials: PS
authors.lastname: Ge
authors.forename: David
authors.initials: D
authors.lastname: Rigberg
authors.forename: Christian
authors.initials: C
authors.lastname: de Virgilio
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017544:Aortic Aneurysm, Abdominal / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D001019:Aortic Rupture / Q000382:microbiology* / Q000601:surgery; D001027:Aortography / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D004927:Escherichia coli Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents