Histopathological spectrum of childhood nephrotic syndrome in different hospitals of Dhaka City.
Nephrotic syndrome in children is a clinical manifestation of different histopathological subtypes of glomerulopathies. There is a paucity of studies about the histopathological spectrum of childhood nephrotic syndrome in our country. A cross sectional study was carried out from July 2005 to June 2007 with the aim to see the pattern of glomerulonephritis in renal biopsy samples of childhood nephrotic syndrome along with types of immune deposition. Thirty paediatric patients with their relevant clinical history and renal biopsy were evaluated by light microscopic study and by immunofluorescence microscopy. Mesangial-proliferative glomerulonephritis was found to be the most common cause of nephrotic syndrome followed by minimal change disease in the present study. IgM was found to be the most frequent form of immune deposition in case of mesangial proliferative glomerulonephritis.
Huq
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Department of Pathology, Dhaka Medical College, Dhaka, Bangladesh.
Akond
A K
AK
Kabir
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E
D000293:Adolescent; D000367:Age Factors; D001459:Bangladesh; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000473:pathology*