[Systemic prokinetic treatment of postoperative ileus following abdominal surgery. Assessment of a Cochrane review].
Based on the evidence presented in the Cochrane review "Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults", routine administration of systemic prokinetics for the prevention of postoperative ileus is not recommendable. The potential of selective opioid antagonists and intravenous lidocaine should be further investigated, particularly in conjunction with laparoscopic surgery, epidural pain management and fast-track surgery.
Holte
Kathrine
K
Kirurgisk Gastroenterologisk Afdeling 435, Hvidovre Hospital, DK-2650 Hvidovre, Denmark. kathrine.holte@dadlnet.dk
D000005:Abdomen / Q000601:surgery*; D019317:Evidence-Based Medicine; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D045823:Ileus / Q000188:drug therapy* / Q000209:etiology; D011183:Postoperative Complications / Q000188:drug therapy*
D005765:Gastrointestinal Agents