title: [Expression of thymic stromal lymphopoietin in nasal mucosa of a mouse model with allergic rhinitis].
abstract: OBJECTIVE
  To investigate the expression of thymic stromal lymphopoietin (TSLP) in the nasal mucosa of mouse with allergic rhinitis.
  
  
  METHODS
  Twenty wide type BALB/c mouse were divided into 2 groups randomly. Two groups were included, allergic rhinitis group (group A) and control group (group B). The mouse model of allergic rhinitis was established by ovalbumin (OVA) sensitization and challenge. The expressions of TSLP in the nasal mucosa was determined by realtime quantitative PCR and immunohistochemical method.
  
  
  RESULTS
  The expression of TSLP in the nasal mucosa of group A was significantly higher than that in group B (P<0.01).
  
  
  CONCLUSIONS
  TSLP plays a role in the mouse model of allergic rhinitis.
authors.affiliation: Department of ICU, Zhongshan Hospital, Xiamen University, Xiamen, 361004, China.
authors.forename: Meili
authors.initials: M
authors.lastname: Xu
authors.forename: Yongqing
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism*; D004195:Disease Models, Animal; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D009297:Nasal Mucosa / Q000378:metabolism*; D010047:Ovalbumin / Q000096:biosynthesis; D012221:Rhinitis, Allergic, Perennial / Q000378:metabolism*; D000094632:Thymic Stromal Lymphopoietin
chemical_list: D016207:Cytokines; D010047:Ovalbumin; D000094632:Thymic Stromal Lymphopoietin; C000721967:TSLP protein, mouse