Sensitivity and specificity of BCG scar reading among HIV-infected children.
BCG scar has been used as an indicator of vaccination with BCG in the past, but the validity of scar among HIV-positive children is still unknown. The validity of BCG scar reading among such children was estimated, using three different gold standards. The sensitivity ranged from 81.3% (95%-CI: 78.0-84.2) to 91.6% (95%-CI: 88.4-94.0), when the gold standards were, respectively, information from the adult responsible for the child and the vaccination card. The specificity ranged from 90.5% (95% CI: 81.6-95.5) to 94.1% (95% CI: 87.7-97.4), when the gold standards were, respectively, the vaccination card and information from the adult responsible for the child. Reading of BCG scar was shown to be a good indicator for vaccination in the past, among HIV-infected children.
Van-Dunem
Joaquim Carlos Vicente Dias
JC
Departamento de Pediatria, Universidade Agostinho Neto, Av. Amilcar Cabral, s/n, Maianga, Luanda, Angola. jcvandunem@hotmail.com
de Alencar
Luiz Cláudio Arraes
LC
Rodrigues
Laura Cunha
LC
de Albuquerque
Maria de Fátima Pessoa Militão
Mde F
Ramos
Maria Eugénia
ME
Ximenes
Ricardo Arraes de Alencar
RA
D000810:Angola; D001500:BCG Vaccine / Q000008:administration & dosage*; D016022:Case-Control Studies; D002675:Child, Preschool; D002921:Cicatrix; D005260:Female; D006679:HIV Seropositivity / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D008499:Medical Records; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control
D001500:BCG Vaccine