MicroRNAs in cardiovascular biology and heart disease.
MicroRNAs play important roles in many cellular and biological functions via the regulation of mRNA target translation. In the cardiovascular field, microRNAs are now acknowledged as fundamental in regulating the expression of genes that governs physiological and pathological myocardial adaptation to stress. Here, we review recent progress in the understanding of microRNA functions and their involvement in heart disease.
Catalucci
Daniele
D
Istituto di Ricovero e Cura a Carattere Scientifico Multimedica, Milan, Italy.
Gallo
Paolo
P
Condorelli
Gianluigi
G
D001145:Arrhythmias, Cardiac / Q000235:genetics; D002318:Cardiovascular Diseases / Q000235:genetics*; D006331:Heart Diseases / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism
D035683:MicroRNAs; D012333:RNA, Messenger