[Studies on the chemical constituents of Coleus forskohlii].
OBJECTIVE
To study the chemical constituents in the aerial parts of Coleus forskohlii.


METHODS
The compounds were isolated by various column chromatographic methods, and their structures were identified by spectroscopic methods.


RESULTS
Twelve compounds were isolated and identified as chamaecydin (1), 6 alpha-hydroxydemethylcryptojaponol (2), alpha-cedrene (3), oleanolic acid (4), forskolin G (5), forskolin J (6), 1,6-diacetyl-9-deoxyforskolin (7), forskolin A (8), forskolin H (9), 6-acetyl-1-deoxyforskolin (10), betulinic acid (11), beta-sitosterol (12).


CONCLUSIONS
Compounds 1 - 3 are isolated from Coleus genus for the first time, and compound 4 is isolated from C. forskohlii for the first time.
Wang
Ya-qin
YQ
School of Pharmacy, Fudan University, Shanghai 200032, China. wangyq1219@126.com
Ma
Jian-ping
JP
Pan
Sheng-li
SL
Hou
Ai-jun
AJ
Huang
Jian-ming
JM
D031330:Coleus / Q000737:chemistry*; D005576:Colforsin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000737:chemistry / Q000302:isolation & purification*; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C000393:cedrene; D005576:Colforsin; D009828:Oleanolic Acid