title: Seborrheic keratosis of the conjunctiva: a case report.
abstract: Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Clinically, a diagnosis of conjunctival papilloma was made, and a mass excision was performed. The histopathological analysis evidenced a conjunctival-covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. With the above findings, a diagnosis of conjunctival seborrheic keratosis was established. The occurrence of seborrheic keratosis on the conjunctiva is rare. In this case, seborrheic keratosis was confirmed by pathologic report despite its similar appearance with papilloma. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival lesions.
authors.affiliation: Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, #134 Sinchon-dong, Seodaemun-gu, Seoul, Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Hyoung Won
authors.initials: HW
authors.lastname: Bae
authors.forename: Kwang Kil
authors.initials: KK
authors.lastname: Lee
authors.forename: Tae Im
authors.initials: TI
authors.lastname: Kim
authors.forename: Eung Kweon
authors.initials: EK
authors.lastname: Kim
mesh_terms: D000368:Aged; D003229:Conjunctival Diseases / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D017492:Keratosis, Seborrheic / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D033401:Microscopy, Acoustic; D013508:Ophthalmologic Surgical Procedures / Q000379:methods