title: NRG1 and BDNF genes in schizophrenia: an association study in an Italian case-control sample.
abstract: We tested for associations between five single nucleotide polymorphisms (SNPs) located in the area containing the Neuregulin 1 gene (NRG1) and three SNPs within the brain-derived neutrophic factor gene (BDNF) in an Italian sample consisting of 171 schizophrenia subjects and 349 controls. No association was found for any of the polymorphisms tested, either in single locus or in haplotype analysis.
authors.affiliation: Laboratory of Molecular Genetics, Section of Clinical Pharmacology, Department of Neurosciences B.B. Brodie, University of Cagliari, 09042 Monserrato, Cagliari, Italy.
authors.forename: Alessio
authors.initials: A
authors.lastname: Squassina
authors.forename: Paola
authors.initials: P
authors.lastname: Piccardi
authors.forename: Maria
authors.initials: M
authors.lastname: Del Zompo
authors.forename: Alessandro
authors.initials: A
authors.lastname: Rossi
authors.forename: Antonio
authors.initials: A
authors.lastname: Vita
authors.forename: Stefano
authors.initials: S
authors.lastname: Pini
authors.forename: Armida
authors.initials: A
authors.lastname: Mucci
authors.forename: Silvana
authors.initials: S
authors.lastname: Galderisi
mesh_terms: D000328:Adult; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study / Q000379:methods; D005838:Genotype; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D020890:Neuregulin-1 / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*
chemical_list: D019208:Brain-Derived Neurotrophic Factor; D020890:Neuregulin-1