title: A facile synthesis of 2,4-disubstituted thiazoles using MnO2.
abstract: Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO(2)) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or vinyl substitutions at the 2- or 4-position can be obtained in good to excellent yields.
authors.affiliation: Department of Applied Chemistry, China Agricultural University, 100193, Beijing, China. yuyanbo0902@163.com
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Yu
authors.forename: Hong-Liang
authors.initials: HL
authors.lastname: Chen
authors.forename: Li-Yi
authors.initials: LY
authors.lastname: Wang
authors.forename: Xin-Zheng
authors.initials: XZ
authors.lastname: Chen
authors.forename: Bin
authors.initials: B
authors.lastname: Fu
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D017895:Manganese Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D017895:Manganese Compounds; D010087:Oxides; D013844:Thiazoles; C027424:manganese oxide