title: [A case of chemo-radiation therapy with high degree of efficacy for esophageal cancer with liver metastasis].
abstract: A 78-year-old man underwent a radical resection for esophageal cancer (Stage III) and cardiac gastric cancer (Stage IA) at another hospital 2 years ago. After the operation, he was followed at that hospital. In 2008, abdominal CT scan and FDG-PET/CT revealed a liver tumor. He was referred to our hospital and was diagnosed as esophageal cancer with liver metastasis. He received chemo-radiation therapy (CRT). The regimen was docetaxel hydrate (30 mg/m2, day 1, 8, 29 and 36) and S-1 (60 mg/m2, day 1-14 and day 29-45) with radiation (45 Gy) for liver metastasis. He finished the CRT without any hematotoxicity, liver disorder and non-hematotoxic adverse event (grade 3). Abdominal CT was done 2 months after the end of CRT and revealed that the tumor lesion disappeared completely. The patient is alive for 11 months after the CRT without any evidence of recurrence. The tumor disappeared completely for the last 11 months. We conclude that CRT is safe and very effective for esophageal cancer with liver metastasis.
authors.affiliation: Department of Gastroenterological Surgery, Kawasaki Medical School.
authors.forename: Hisako
authors.initials: H
authors.lastname: Kubota
authors.forename: Hideo
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Ai
authors.initials: A
authors.lastname: Saito
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kaida
authors.forename: Haruaki
authors.initials: H
authors.lastname: Murakami
authors.forename: Masaharu
authors.initials: M
authors.lastname: Higashida
authors.forename: Yoko
authors.initials: Y
authors.lastname: Hirabayashi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Oka
authors.forename: Hideo
authors.initials: H
authors.lastname: Okumura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Uragami
authors.forename: Kazuki
authors.initials: K
authors.lastname: Yamashita
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Hirai
authors.forename: Eisaku
authors.initials: E
authors.lastname: Yoden
authors.forename: Junichi
authors.initials: J
authors.lastname: Hiratsuka
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004338:Drug Combinations; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy*; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid