[Detection of selected diuretics in biological fluids by chromatography mass spectrometry].
Modified methods for the detection and measurement of furosemide and spironolactone in biological fluids has been developed based on gas chromatography mass spectrometry. Optimal conditions for chromatography are described for the determination of the diuretic agents of interest. The proposed methods were verified by analysing urine samples obtained from patients with chronic cardiac insufficiency.
Alikhodzhaeva
M I
MI
Simonov
E A
EA
Kirichek
A V
AV
Popkov
V A
VA
D004232:Diuretics / Q000652:urine*; D053593:Forensic Toxicology / Q000379:methods*; D005665:Furosemide / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006333:Heart Failure / Q000652:urine; D006801:Humans; D015203:Reproducibility of Results; D013148:Spironolactone / Q000652:urine*
D004232:Diuretics; D013148:Spironolactone; D005665:Furosemide