Colonic metastasis from a primary adenocarcinoma of the lung presenting with acute abdominal pain: a case report.
Colonic metastasis from lung cancer is rare and generally asymptomatic. Here, we report a case with lung adenocarcinoma that presented with acute abdominal pain due to intestinal obstruction caused by the metastatic colon tumor. The patient underwent emergency colonoscopy and the pathologic report was adenocarcinoma, which was the same as that for a bronchoscopic biopsy from a large lung mass. Immunohistochemistry was positive for thyroid transcription factor-1 and cytokeratin 7, and negative for cytokeratin 20 and caudal-related homeobox transcription factor 2 on both lung biopsy and colon surgical specimens. Accordingly, we used immunohistochemistry for thyroid transcription factor-1, cytokeratin 7, cytokeratin 20 and caudal-related homeobox transcription factor-2 to diagnose primary adenocarcinoma of the lung with colonic metastasis.
Weng
Ming-Wei
MW
Department of Internal Medicine, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan.
Wang
Hong-Chung
HC
Chiou
Jen-Chih
JC
Lin
Shong-Ling
SL
Lai
Ruay-Sheng
RS
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications*; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D008297:Male; D008875:Middle Aged