title: Transperineal sonocystography: new standard for assessing anastomotic leaks after radical prostatectomy.
abstract: OBJECTIVE
  Fluorocystography (FC) is the reference standard for assessing the integrity of the vesicourethral anastomosis after radical prostatectomy (RP). We describe a new technique, transperineal sonocystography (TPSC), as a cost-effective alternative and more informative than FC.
  
  
  METHODS
  Between May 1, 2007, and October 1, 2008, 175 consecutive men underwent open or robotically assisted RP. Before Foley catheter removal, all men underwent both TPSC and FC, which were performed and interpreted by a single radiologist. Transperineal sonocystography was performed first with real-time imaging after gravity filling of the bladder with 150 mL of normal saline. Extravasation of saline was calculated by computer software after outlining the observed pooling of extravasated saline in the transverse and longitudinal views. Fluorocystography was performed after TPSC using our standard protocol, with qualitative classification of anastomotic leaks as none, slight, moderate, or severe.
  
  
  RESULTS
  The mean extravasation volume +/- SEM was 16.3 +/- 2.9 mL. Of the 175 patients, 142 (81.2%) showed no anastomotic leaks on TPSC. Of the remaining 33 patients (18.8%), TPSC identified 20 (11.4%), 13 (7.4%), and 0 patients with slight, moderate, and severe leaks, respectively. Excellent concordance was shown between TPSC and FC.
  
  
  CONCLUSIONS
  Transperineal sonocystography was equivalent to FC in detecting anastomotic leaks after RP. It provides a safe, inexpensive, and effective alternative to traditional FC for evaluating the integrity of the vesicourethral anastomosis after RP.
authors.affiliation: Department of Urology, New York University, New York, New York 10016, USA. shpetim.telegrafi@nyumc.org
authors.forename: Shpetim
authors.initials: S
authors.lastname: Telegrafi
authors.forename: Timothy
authors.initials: T
authors.lastname: Ito
authors.forename: Mariana
authors.initials: M
authors.lastname: Kozirovsky
authors.forename: Juliana
authors.initials: J
authors.lastname: Laze
authors.forename: Herbert
authors.initials: H
authors.lastname: Lepor
mesh_terms: D000368:Aged; D000714:Anastomosis, Surgical / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010502:Perineum / Q000000981:diagnostic imaging*; D011468:Prostatectomy / Q000009:adverse effects*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013529:Surgical Wound Dehiscence / Q000000981:diagnostic imaging* / Q000209:etiology*; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*