[Preoperative second-derivative of photoplethysmography measurement predicts the hemodynamic response to general anaesthesia induction].
BACKGROUND
Second-derivative of photoplethysmography (SDPTG) is a non-invasive method for the assessment of structural and functional arterial properties. We studied the hemodynamic responses to induction of anaesthesia and whether SDPTG could be used in predicting these responses.


METHODS
SDPTG was performed in 71 subjects (35 males, 36 females) undergoing general anaesthesia for elective operation. Anaesthesia was inducted with propofol 2 mg x kg(-1), fentanyl 2 microg x kg(-1), vecuronium 0.1 mg x kg(-1), and sevoflurane 3% in a mixture of 100% oxygen.


RESULTS
The SDPTG indices (b/a and d/a values) significantly correlated with the percentage decrease in systolic blood pressure in both genders. Regression equations (x = SDPTG indices, y = percentage of decrease in systolic blood pressure) were as follows: (1) b/a, r(male) = 0.39, P < 0.05, y = 23.26x + 40.67; r(female) = 0.39, P < 0.05, y = 17.95x + 39.61; (2) d/a, r(male) = -0.37, P < 0.05, y = -31.29x + 16.22 and r(female) = -0.48, P < 0.01, y = -34.46x + 18.55.


CONCLUSIONS
These results suggest that preoperative SDPTG is useful in predicting the hemodynamic response to induction of general anaesthesia.
Obara
Shinju
S
Department of Anaesthesiology, Fukushima Medical University School of Medicine, Fukushima 960-1295.
Imaizumi
Tsuyoshi
T
Ohashi
Satoshi
S
Nakano
Yuko
Y
Takahashi
Shin-Ichiro
S
Hayashi
Shiho
S
Iida
Hiroshi
H
Akatsu
Masahiko
M
Isosu
Tsuyoshi
T
Murakawa
Masahiro
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D005260:Female; D005283:Fentanyl; D005544:Forecasting; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D008991:Monitoring, Physiologic; D017156:Photoplethysmography; D057234:Preoperative Period; D015742:Propofol; D000077149:Sevoflurane; D014673:Vecuronium Bromide; D055815:Young Adult
D008738:Methyl Ethers; D000077149:Sevoflurane; D014673:Vecuronium Bromide; D005283:Fentanyl; D015742:Propofol