Weight change patterns among breast cancer survivors: results from the Shanghai breast cancer survival study.
In a population-based cohort study of 5,014 women with stage 0-III breast cancer, we evaluated weight change patterns from diagnosis to 6, 18, and 36 months post-diagnosis. Patients were recruited to the study approximately 6 months after cancer diagnosis between 2002 and 2006 and followed through 36 months post-diagnosis. The medians of weight change from diagnosis to 6, 18, and 36 months post-diagnosis were 1.0, 2.0, and 1.0 kg, respectively. Approximately, 26% of survivors gained > or =5% of their at-diagnosis body weight during the first 6 months after diagnosis, while 37% and 33% of women gained the same percentage of weight at 18 and 36 months post-diagnosis. More weight gain was observed among women who had a more advanced disease stage, were younger, had lower body mass index at diagnosis, were premenopausal, or received chemotherapy or radiotherapy during the first 6 months after cancer diagnosis. Multivariate analyses indicated that age at diagnosis, body size, comorbidity, and disease stage independently predicted weight gain from diagnosis to 36 months post-diagnosis. In summary, weight gain is common over the first 3 years after breast cancer diagnosis among Chinese women. More research is needed to investigate measures to prevent weight gain in breast cancer survivors.
Gu
Kai
K
Shanghai Institute of Preventive Medicine, 1380 Zhong Shan Road (W), 200336 Shanghai, China.
Chen
Xiaoli
X
Zheng
Ying
Y
Chen
Zhi
Z
Zheng
Wei
W
Lu
Wei
W
Shu
Xiao Ou
XO
D000328:Adult; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D002681:China; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D017741:Survivors; D013997:Time Factors; D015430:Weight Gain / Q000502:physiology*