title: Prospective assessment of multiple cardiac papillary fibroelastomas: an echocardiographic and surgical study.
abstract: Multiple cardiac papillary fibroelastomas (PFEs) are thought to account for less than 10% of patients with PFE. We aimed at evaluating the frequency and location of multiple PFEs and the reliability of transthoracic (TTE) and transoesophageal (TEE) echocardiography in diagnosing multiple PFEs. Twenty-six consecutive patients (52±14 years, 65% males) with pathologically confirmed PFE had 21 PFEs diagnosed by TTE, 33 by TEE, and 62 at surgery. Eight patients (31%) had multiple PFEs found either by TEE or at surgery. Aortic valve was involved in 75% of patients with multiple PFEs and left ventricle in 38% of patients. The sensitivity of TTE in diagnosing any PFEs was 51.3% and 76.9% for TEE. Our study emphasizes the high frequency of multiple PFEs, the need of TEE for all presumed PFE and the need for careful assessment of left-sided endocardial surfaces, especially of the aortic valve, during PFE excision.
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France; CHU Nantes, l'Institut du Thorax, Nantes F-4400, France; University Lille 2, Institut Fédératif de Recherche 114, EA 2693, Faculté de Médecine, Lille F-59045, France. Electronic address: thletourneau@yahoo.fr.
authors.forename: Thierry
authors.initials: T
authors.lastname: Le Tourneau
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Betto
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France.
authors.forename: Marjorie
authors.initials: M
authors.lastname: Richardson
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France; University Lille 2, Institut Fédératif de Recherche 114, EA 2693, Faculté de Médecine, Lille F-59045, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Juthier
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France; University Lille 2, Institut Fédératif de Recherche 114, EA 2693, Faculté de Médecine, Lille F-59045, France.
authors.forename: Pierre Vladimir
authors.initials: PV
authors.lastname: Ennezat
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Polge
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Bauters
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France; University Lille 2, Institut Fédératif de Recherche 114, EA 2693, Faculté de Médecine, Lille F-59045, France.
authors.forename: André
authors.initials: A
authors.lastname: Vincentelli
authors.affiliation: CHU Lille, Hopital Cardiologique, Lille F-59045, France.
authors.forename: Ghislaine
authors.initials: G
authors.lastname: Deklunder
mesh_terms: D000328:Adult; D000368:Aged; D017548:Echocardiography, Transesophageal / Q000379:methods; D005260:Female; D005350:Fibroma / Q000000981:diagnostic imaging* / Q000601:surgery*; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010210:Papillary Muscles / Q000000981:diagnostic imaging* / Q000601:surgery*; D011446:Prospective Studies