[Specific ototoxic effects of monomycin in immature animals].
Dynamics of the hearing function was evaluated using immature animals based on the SSCP data. Morphological characteristics of the cochlear auditory ganglion were studied after administration of therapeutic doses of the ototoxic antibiotic monomycin. Untreated animals served as controls. The results of morphofunctional investigations were evaluated in comparison with the similar data obtained in adult cats after injection of the same doses of monomycin.
Bogomil'skiĭ
M R
MR
Dreval'
A A
AA
D'iakonova
I N
IN
Rakhmanova
I V
IV
Tikhomirov
A M
AM
Iarygin
V N
VN
D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D002415:Cats; D015643:Erythromycin Ethylsuccinate / Q000633:toxicity*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D008854:Microscopy, Electron; D013136:Spiral Ganglion / Q000187:drug effects / Q000503:physiopathology / Q000648:ultrastructure*
D000900:Anti-Bacterial Agents; D015643:Erythromycin Ethylsuccinate