From machine learning to natural product derivatives that selectively activate transcription factor PPARgamma.
Rupp
Matthias
M
Goethe University, Chair for Chem- and Bioinformatics, LIFF, ZAFES, Siesmayerstr. 70, 60323 Frankfurt a.M., Germany.
Schroeter
Timon
T
Steri
Ramona
R
Zettl
Heiko
H
Proschak
Ewgenij
E
Hansen
Katja
K
Rau
Oliver
O
Schwarz
Oliver
O
Müller-Kuhrt
Lutz
L
Schubert-Zsilavecz
Manfred
M
Müller
Klaus-Robert
KR
Schneider
Gisbert
G
D000818:Animals; D001185:Artificial Intelligence; D001688:Biological Products / Q000737:chemistry* / Q000494:pharmacology; D019556:COS Cells; D002522:Chlorocebus aethiops; D003503:Cyclobutanes / Q000737:chemistry / Q000494:pharmacology; D015195:Drug Design; D047495:PPAR gamma / Q000819:agonists* / Q000378:metabolism; D013329:Structure-Activity Relationship
D001688:Biological Products; D003503:Cyclobutanes; D047495:PPAR gamma; C003731:truxillic acid