title: [A case of acute interstitial pneumonia successfully treated with polymyxin B-immobilized fiber column direct hemoperfusion].
abstract: A 65-year-old man was admitted because of rapidly progressing respiratory failure with diffuse ground glass opacities according to chest radiography. Acute interstitial pneumonia (AIP) was diagnosed because of diffuse alveolar damage shown by a transbronchial lungs biopsy and the exclusion of any underlying diseases such as infectious diseases. Because steroid pulse therapy did not improve his condition, he was then treated with polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP), with excellent results. PMX-DHP should be considered as one of the treatment options for suspected AIP when steroid pulse therapy is ineffective.
authors.affiliation: National Hospital Organization (NHO) Tokyo National Hospital.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shimada
authors.forename: Shinobu
authors.initials: S
authors.lastname: Akagawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kawashima
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Masuda
authors.forename: Atsuhisa
authors.initials: A
authors.lastname: Tamura
authors.forename: Akira
authors.initials: A
authors.lastname: Hebisawa
mesh_terms: D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004731:Endotoxins / Q000097:blood; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000628:therapy*; D008297:Male; D011112:Polymyxin B / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D004731:Endotoxins; D011112:Polymyxin B