[A case of acute interstitial pneumonia successfully treated with polymyxin B-immobilized fiber column direct hemoperfusion].
A 65-year-old man was admitted because of rapidly progressing respiratory failure with diffuse ground glass opacities according to chest radiography. Acute interstitial pneumonia (AIP) was diagnosed because of diffuse alveolar damage shown by a transbronchial lungs biopsy and the exclusion of any underlying diseases such as infectious diseases. Because steroid pulse therapy did not improve his condition, he was then treated with polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP), with excellent results. PMX-DHP should be considered as one of the treatment options for suspected AIP when steroid pulse therapy is ineffective.
Shimada
Masahiro
M
National Hospital Organization (NHO) Tokyo National Hospital.
Akagawa
Shinobu
S
Kawashima
Masahiro
M
Masuda
Kimihiko
K
Tamura
Atsuhisa
A
Hebisawa
Akira
A
D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004731:Endotoxins / Q000097:blood; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000628:therapy*; D008297:Male; D011112:Polymyxin B / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004731:Endotoxins; D011112:Polymyxin B