Synthetic approach to polysubstituted furans: an efficient addition/oxidative cyclization of alkynoates and 1,3-dicarbonyl compounds.
A novel and reliable method for the direct construction of polysubstituted furans is reported. The key transformation involves Sn(II)- and Cu(I)-involved addition/oxidative cyclization of alkynoates and 1,3-dicarbonyl compounds in the presence of 2,3-dichloro-5,6-dicyanobenzoquinone.
Liu
Weibing
W
School of Chemistry and Chemical Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.
Jiang
Huanfeng
H
Zhang
Min
M
Qi
Chaorong
C
D000480:Alkynes / Q000737:chemistry*; D016227:Benzoquinones / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000480:Alkynes; D016227:Benzoquinones; D005663:Furans; D007659:Ketones; C000928:dichlorodicyanobenzoquinone