title: Localized perineal cutaneous nodules: a case of recurrent systemic anaplastic large-cell lymphoma.
abstract: We report an unusual case of localized cutaneous nodules heralding the recurrence of systemic CD30+ anaplastic large-cell lymphoma (ALCL). A 47-year-old woman developed numerous violaceous nodules in the perineal and upper thigh area 3 years after multimodal treatment and complete remission of primary anaplastic large-cell CD30+ lymphoma. Using immunohistochemical and T-cell gene rearrangement analysis, a recurrence of her anaplastic large-cell lymphoma was diagnosed.
authors.affiliation: Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA.
authors.forename: C
authors.initials: C
authors.lastname: Hernandez
authors.forename: S N
authors.initials: SN
authors.lastname: Puangsuvan
authors.forename: A
authors.initials: A
authors.lastname: Peterson
authors.forename: J K
authors.initials: JK
authors.lastname: Robinson
mesh_terms: D002471:Cell Transformation, Neoplastic / Q000235:genetics; D005260:Female; D015329:Gene Rearrangement, T-Lymphocyte / Q000235:genetics; D006801:Humans; D017730:Ki-1 Antigen / Q000235:genetics; D017728:Lymphoma, Large-Cell, Anaplastic / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D033581:Stem Cell Transplantation; D016896:Treatment Outcome
chemical_list: D017730:Ki-1 Antigen