title: Impact of co-occurring psychiatric disorders on retention in a methadone maintenance program: an 18-month follow-up study.
abstract: We assess the influence of co-occurring psychiatric disorders on retention in 189 opioid dependent patients in a methadone maintenance treatment (MMT) and determine the incidence of psychiatric co-morbidity during an 18-month follow-up period. About 68.5 % were retained in the MMT. Neither co-occurring mental disorders (chi-square = 0.303, df = 1, p = 0.622) nor methadone doses [85 (88.9) vs. 79.2 (85) mg/day, p = 0.672] were related to retention. In the follow-up period 19 new diagnoses were made, mainly major depression and antisocial and borderline personality disorders. Co-occurring psychiatric disorders should be assessed during MMT follow-up.
authors.affiliation: Institute of Psychiatry and Addiction, Hospital del Mar and Institut Municipal d'Investigació Mèdica, Barcelona, Spain. mastals@imas.imim.es
authors.forename: Mònica
authors.initials: M
authors.lastname: Astals
authors.forename: Laura
authors.initials: L
authors.lastname: Díaz
authors.forename: Antònia
authors.initials: A
authors.lastname: Domingo-Salvany
authors.forename: Rocío
authors.initials: R
authors.lastname: Martín-Santos
authors.forename: Antoni
authors.initials: A
authors.lastname: Bulbena
authors.forename: Marta
authors.initials: M
authors.lastname: Torrens
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D000987:Antisocial Personality Disorder / Q000453:epidemiology; D001883:Borderline Personality Disorder / Q000453:epidemiology; D016001:Confidence Intervals; D003865:Major Depressive Disorder / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D008691:Methadone / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D010349:Patient Compliance; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D016320:Substance Abuse Treatment Centers; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid; D008691:Methadone