title: Does age at orchidopexy impact on the results of testicular sperm extraction?
abstract: The aim of this study was to evaluate the affect of age at the time of orchidopexy on testicular sperm extraction (TESE) results among patients with a history of cryptorchidism and azoospermia. This retrospective study compared TESE results for couples undergoing IVF treatment, among two groups of patients. Group A included patients who underwent orchidopexy at age 10 and younger, and group B included patients who had the procedure above the age of 10. A total of 42 patients were included in the study. Forty patients had bilateral cryptorchidism and two had unilateral. The overall rate of sperm recovery was 59.5%. No differences were found in the sperm retrieval, fertilization, implantation, pregnancy, or live birth rates between the groups. The results suggest that age at orchidopexy, either at 10 years of age or younger or above 10 years of age, was not a predictive factor for successful TESE. Although bilateral cryptorchidism is usually considered a testicular secretory dysfunction, it was found that sperm retrieval attempts yielded spermatozoa in almost 60% of patients with azoospermia and a history of cryptorchidism.
authors.affiliation: IVF and Andrology Units, Division of Obstetrics and Gynecology, The Chaim Sheba Medical Centre, Tel Hashomer, Affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. wiserniv@netvision.net.il
authors.forename: A
authors.initials: A
authors.lastname: Wiser
authors.forename: G
authors.initials: G
authors.lastname: Raviv
authors.forename: R
authors.initials: R
authors.lastname: Weissenberg
authors.forename: S E
authors.initials: SE
authors.lastname: Elizur
authors.forename: J
authors.initials: J
authors.lastname: Levron
authors.forename: R
authors.initials: R
authors.lastname: Machtinger
authors.forename: I
authors.initials: I
authors.lastname: Madgar
mesh_terms: D000328:Adult; D000367:Age Factors; D053713:Azoospermia / Q000209:etiology / Q000601:surgery; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000150:complications / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007223:Infant; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D056126:Orchiopexy / Q000379:methods*; D009929:Organ Size; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D053625:Sperm Retrieval; D013737:Testis / Q000033:anatomy & histology / Q000601:surgery*
chemical_list: D005640:Follicle Stimulating Hormone