title: Short access to (+)-lupinine and (+)-epiquinamide via double hydroformylation.
abstract: Short and efficient access to (+)-lupinine and (+)-epiquinamide by means of an unprecedented double hydroformylation of a bis-homoallylic azide followed by a tandem catalytic hydrogenation/reductive bis-amination is reported.
authors.affiliation: Faculté de Pharmacie, UMR 7200, CNRS-Université de Strasbourg, Laboratoire d'Innovation Thérapeutique, 74 route du Rhin, F-67401 Illkirch, France.
authors.forename: Etienne
authors.initials: E
authors.lastname: Airiau
authors.forename: Thomas
authors.initials: T
authors.lastname: Spangenberg
authors.forename: Nicolas
authors.initials: N
authors.lastname: Girard
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit
authors.forename: André
authors.initials: A
authors.lastname: Mann
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D011807:Quinolizines / Q000138:chemical synthesis* / Q000737:chemistry; D013034:Sparteine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism; D000093843:Quinolizidine Alkaloids
chemical_list: D000470:Alkaloids; D001386:Azides; D011807:Quinolizines; D013034:Sparteine; C481035:epiquinamide; C015971:lupinine; D000093843:Quinolizidine Alkaloids