title: Case report: exercise-associated hyponatremia with rhabdomyolysis during endurance exercise.
abstract: Exercise-associated hyponatremia (EAH) has been well described in the literature, and its pathogenesis has been elucidated. The most common presenting symptoms of EAH are confusion or severe alterations in mental status. Although rhabdomyolysis in association with hyponatremia has been described in other settings, only 1 case of EAH associated with rhabdomyolysis at presentation has been previously described. In this article, we report on the occurrence of EAH with rhabdomyolysis in 4 athletes participating in the West Highland Way Race, a 95-mile endurance foot race. The pathogenesis of this association is described with implications for therapy.
authors.affiliation: Kinlochleven Medical Pratice, Scotland.
authors.forename: Christopher
authors.initials: C
authors.lastname: Ellis
authors.forename: Jennifer
authors.initials: J
authors.lastname: Cuthill
authors.forename: Tamara
authors.initials: T
authors.lastname: Hew-Butler
authors.forename: Sajid Melvin
authors.initials: SM
authors.lastname: George
authors.forename: Mitchell H
authors.initials: MH
authors.lastname: Rosner
mesh_terms: D000328:Adult; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007010:Hyponatremia / Q000209:etiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010807:Physical Endurance; D012206:Rhabdomyolysis / Q000209:etiology* / Q000628:therapy; D012420:Running
chemical_list: D004232:Diuretics; D005665:Furosemide