Lung function and airway diseases.
Two studies report genome-wide association studies for lung function, using cross-sectional spirometric measurements in healthy individuals. They identify six genetic loci newly associated to natural variation in lung function, which may have implications for the related airway diseases of asthma and chronic obstructive pulmonary disease.
Weiss
Scott T
ST
D005541:Forced Expiratory Volume; D020869:Gene Expression Profiling; D055106:Genome-Wide Association Study / Q000379:methods*; D005982:Glutathione Transferase / Q000235:genetics; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000502:physiology* / Q000503:physiopathology; D015201:Meta-Analysis as Topic; D008840:Microfilament Proteins / Q000235:genetics; D000067759:Receptor for Advanced Glycation End Products; D011971:Receptors, Immunologic / Q000235:genetics; D044422:Receptors, Serotonin, 5-HT4 / Q000235:genetics; D012129:Respiratory Function Tests; D000070876:Tensins; D019699:Thrombospondins / Q000235:genetics; D014797:Vital Capacity
D008840:Microfilament Proteins; D000067759:Receptor for Advanced Glycation End Products; D011971:Receptors, Immunologic; D000070876:Tensins; D019699:Thrombospondins; D044422:Receptors, Serotonin, 5-HT4; D005982:Glutathione Transferase