title: Primary cutaneous CD30+ large-cell lymphoma presenting as a scrotal plaque.
abstract: Primary cutaneous CD30+ large-cell lymphoma (CD30+ LCL) is a rare subtype of cutaneous T cell lymphoma. We report a patient with a one-year history of an enlarging scrotal plaque. Skin biopsy stained positive for CD30, and after thorough systemic evaluation, a diagnosis of primary cutaneous CD30+ LCL was made. Most commonly CD30+ LCL presents on the extremities and trunk. We present the first case to our knowledge of a patient initially presenting with a solitary scrotal nodule. When primary cutaneous CD30+ LCL is suspected, it is important to conduct a thorough systemic evaluation for systemic LCL and immunohistological studies for CD30- types. Ruling these conditions out will prevent unnecessarily aggressive treatment for primary cutaneous CD30+ LCL, an indolent disease with a favorable prognosis.
authors.affiliation: Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Sapna
authors.initials: S
authors.lastname: Modi
authors.forename: Deborah J
authors.initials: DJ
authors.lastname: Yang
authors.forename: Norman
authors.initials: N
authors.lastname: Sule
authors.forename: Ted
authors.initials: T
authors.lastname: Rosen
mesh_terms: D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D054446:Lymphoma, Primary Cutaneous Anaplastic Large Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012611:Scrotum