Depression and anxiety: their predictive function for weight loss in obese individuals.
OBJECTIVE
To investigate the impact of current mental disorders on weight loss with special consideration of depressive and/or anxiety disorders as well as binge eating behavior in obese individuals undergoing different weight loss treatments.


METHODS
Three different samples of obese individuals were investigated in a prospective, longitudinal study: participants in a conventional weight loss treatment program (CONV TREAT; n = 250), obesity surgery patients (OBES SURG; n = 153), and obese control individuals (OC; n = 128). Current mental disorders and BMI were assessed at baseline and at 4-year follow-up.


RESULTS
OBES SURG patients with a depressive and/or anxiety disorder lost significantly less weight compared with those without a comorbid mental diagnosis. This result was not detected for CONV TREAT participants. A trend to gain weight was seen in OC participants with a depressive and/or anxiety disorder, whereas OC participants without current mental disorders at baseline lost some weight. Binge eating behavior at baseline did not predict weight loss at 4-year followup.


CONCLUSIONS
These results underline the importance of addressing current depressive and anxiety disorders in obese patients, especially when such patients are undergoing obesity surgery.
Legenbauer
Tanja
T
Abteilung fur Psychosomatische Medizin und Psychotherapie, LWL-Klinik Dortmund, Universitatsklinikum der Ruhr-Universitat Bochum, Dortmund, Germany. tanja.legenbauer@ruhr-uni-bochum.de
De Zwaan
Martina
M
Benecke
Andrea
A
Muhlhans
Barbara
B
Petrak
Frank
F
Herpertz
Stephan
S
D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D050110:Bariatric Surgery; D015992:Body Mass Index; D002032:Bulimia / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D015430:Weight Gain; D015431:Weight Loss