Top-down flow of visual spatial attention signals from parietal to occipital cortex.
Given the complexity of our visual environment, the ability to selectively attend to certain locations, while ignoring others, is crucial for reducing the amount of visual information to manageable levels and for optimizing behavioral performance. Sustained allocation of spatial attention causes persistent increases in functional magnetic resonance imaging (fMRI) signals in portions of early visual cortex that retinotopically represent the attended location, even in the absence of a visual stimulus. Here we test the hypothesis that topographically organized posterior parietal cortical areas IPS1 and IPS2 transmit top-down spatial attention signals to early visual cortex. We employed fMRI and coherency analysis to measure functional connectivity among cortical areas V1, V2, V3, V3A, V3B, V7, IPS1, and IPS2 during sustained visual spatial attention. Attention increased the magnitude of coherency for many pairs of areas in occipital and parietal cortex. Additionally, attention-related activity in IPS1 and IPS2 led activity in several visual cortical areas by a few hundred milliseconds. These results are consistent with transmission of top-down spatial attention signals from IPS1 and IPS2 to early visual cortex.
Lauritzen
Thomas Z
TZ
Redwood Center for Theoretical Neuroscience, Helen Wills Neuroscience Institute, Henry H. Wheeler Jr. Brain Imaging Center, School of Optometry, University of California, Berkeley, CA 94720-3220, USA. tzl@berkeley.edu
D'Esposito
Mark
M
Heeger
David J
DJ
Silver
Michael A
MA
D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D006801:Humans; D009415:Nerve Net / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*