title: Metastatic pulmonary adenocarcinoma to placenta and pleural fluid: clinicopathologic findings.
abstract: OBJECTIVE
  To report the clinicopathologic findings of a pregnant woman with Stage IV adenocarcinoma of the lung with placental metastasis.
  
  
  METHODS
  Medical records review.
  
  
  RESULTS
  A 31-year-old G(2)P(1001) woman was diagnosed with Stage IV metastatic adenocarcinoma of the lung. At 34 weeks' and 2 days' gestation, she went into preterm labor and delivered a live male infant, weighing 2595 grams, with Apgar scores of 9 and 9, respectively. Placental pathology was significant for adenocarcinoma with a solid and acinar pattern, consistent with that from the lung. Her postpartum course was uneventful. She did not receive chemotherapy and expired one month postpartum. To date, the infant is without evidence of disease.
  
  
  CONCLUSIONS
  The occurance of lung cancer in pregnancy is rare and a few cases have been reported in literature. Placental metastasis is extremely uncommon in these cases and can lead to fetal involvement by lung tumor. It is important to report all cases of lung cancer occurring in pregnancy with subsequent close clinical surveillance of the infant as all cases have a different clinical picture.
authors.affiliation: Department of Obstetrics and Gynecology, Kern Medical Center-UCLA, Bakersfield, California 93305, USA.
authors.forename: Marylou C
authors.initials: MC
authors.lastname: Thelmo
authors.forename: Ellen P
authors.initials: EP
authors.lastname: Shen
authors.forename: Savita
authors.initials: S
authors.lastname: Shertukde
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D009367:Neoplasm Staging; D010922:Placenta Diseases / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000473:pathology*; D011247:Pregnancy