LOH analysis should not be used as a tool to assess whether UVs of BRCA1/2 are pathogenic or not.
Beristain
E
E
Molecular Genetics Laboratory, Department of Biochemistry, Hospital de Cruces, Pza. de Cruces s/n, 48903, Barakaldo, Bizkaia, Spain. eberistain001@ikasle.ehu.es
Guerra
I
I
Vidaurrazaga
N
N
Burgos-Bretones
J
J
Tejada
M I
MI
D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D020022:Genetic Predisposition to Disease; D006801:Humans; D019656:Loss of Heterozygosity; D010051:Ovarian Neoplasms / Q000235:genetics*