title: [Cholesterol crystal embolism and renal insufficiency: case report and literature review].
abstract: Cholesterol crystal embolism with renal impairment is increasingly recognised as an iatrogenic complication of invasive vascular procedures. We present a 58-year-old patient in whom the presence of a classic triad of precipitating event (coronary angiography), subacute presentation of renal failure and cutaneous lesions (livedo reticularis and Blue Toe syndrome) suggested this entity. The confirmatory diagnosis was made by means of renal biopsy which revealed cholesterol crystals lodged in arteries. In our patient severe renal insufficiency requiering hemodialysis ensued. Glucocorticoid and statin therapy failed to recover the renal function. The patient died from acute myocardial infarction. Invasive cardiac procedures are increasing in number especially in the elderly population so higher incidence of cholesterol crystal embolism coud be expected in the future. Increased awareness of this syndrome is necessary for early recognition, which is crucial for treatment, and defining the high-risk patient in whom other modalities of coronary diagnostics coud be considered.
authors.affiliation: Klinika za unutarnje bolesti, Klinicka bolnica Dubrava, Zagreb.
authors.forename: Silva
authors.initials: S
authors.lastname: Puksić
authors.forename: Visnja
authors.initials: V
authors.lastname: Haris
authors.forename: Danica
authors.initials: D
authors.lastname: Ljubanović
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Durasević
authors.forename: Kresimir
authors.initials: K
authors.lastname: Galesić
mesh_terms: D018438:Blue Toe Syndrome / Q000209:etiology; D017023:Coronary Angiography / Q000009:adverse effects*; D017700:Embolism, Cholesterol / Q000209:etiology*; D006801:Humans; D007866:Leg / Q000098:blood supply; D054068:Livedo Reticularis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000209:etiology*