Unsuspected prenatal opioid exposure: long-term detection by alternative matrices.
We describe a suspicious case involving a previous heroin addict and her newborn child experiencing symptoms suggestive of withdrawal. Therapeutic drug monitoring was used to determine whether in utero exposure took place.
Moller
Monique
M
Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario Canada.
Koren
Gideon
G
D003975:Diazepam / Q000009:adverse effects; D016903:Drug Monitoring / Q000379:methods; D005260:Female; D003932:Heroin / Q000009:adverse effects*; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects; D007231:Infant, Newborn; D008297:Male; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis* / Q000209:etiology; D011247:Pregnancy
D006993:Hypnotics and Sedatives; D003932:Heroin; D003975:Diazepam