title: How should DSM-V classify eating disorder not otherwise specified (EDNOS) presentations in women with lifetime anorexia or bulimia nervosa?
abstract: OBJECTIVE
  Anorexia nervosa (AN) and bulimia nervosa (BN) are marked by longitudinal symptom fluctuations. DSM-IV-TR does not address how to classify eating disorder (ED) presentations in individuals who no longer meet full criteria for these disorders. To consider this issue, we examined subthreshold presentations in women with initial diagnoses of AN and BN.
  
  
  METHODS
  A total of 246 women with AN or BN were followed for a median of 9 years; weekly symptom data were collected at frequent intervals using the Longitudinal Interval Follow-up Evaluation of Eating Disorders (LIFE-EAT-II). Outcomes were ED presentations that were subthreshold for 3 months, including those narrowly missing full criteria for AN or BN, along with binge eating disorder (BED) and purging disorder.
  
  
  RESULTS
  During follow-up, most women (77.6%) experienced a subthreshold presentation. Subthreshold presentation was related to intake diagnosis (Wald chi2=8.065, df=2, p=0.018). Individuals with AN most often developed subthreshold presentations resembling AN; those with BN were more likely to develop subthreshold BN. Purging disorder was experienced by half of those with BN and one-quarter of those with AN binge/purge type (ANBP); BED occurred in 20% with BN. Transition from AN or BN to most subthreshold types was associated with improved psychosocial functioning (p<0.001).
  
  
  CONCLUSIONS
  Subthreshold presentations in women with lifetime AN and BN were common, resembled the initial diagnosis, and were associated with modest improvements in psychosocial functioning. For most with lifetime AN and BN, subthreshold presentations seem to represent part of the course of illness and to fit within the original AN or BN diagnosis.
authors.affiliation: Harris Center, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: K T
authors.initials: KT
authors.lastname: Eddy
authors.forename: S A
authors.initials: SA
authors.lastname: Swanson
authors.forename: R D
authors.initials: RD
authors.lastname: Crosby
authors.forename: D L
authors.initials: DL
authors.lastname: Franko
authors.forename: S
authors.initials: S
authors.lastname: Engel
authors.forename: D B
authors.initials: DB
authors.lastname: Herzog
mesh_terms: D000855:Anorexia / Q000145:classification* / Q000175:diagnosis / Q000523:psychology; D052018:Bulimia Nervosa / Q000145:classification* / Q000175:diagnosis / Q000523:psychology; D016009:Chi-Square Distribution; D039721:Diagnostic and Statistical Manual of Mental Disorders; D001068:Feeding and Eating Disorders / Q000145:classification* / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D016014:Linear Models; D008137:Longitudinal Studies; D008390:Markov Chains; D011584:Psychology; D012917:Social Adjustment; D055815:Young Adult