title: Abrupt regression of a meningioma after discontinuation of cyproterone treatment.
abstract: The multiplicity of meningiomas or abrupt lesion growth in patients treated with cyproterone acetate suggests that this progestative treatment may promote lesion growth. We report the rapid regression of an incidental meningioma after discontinuation of a 10-year cyproterone acetate treatment. This unique observation suggests that conservative management of meningiomas may be the best option among users of high doses of cyproterone acetate, given that spontaneous regression may occur after hormonal treatment discontinuation.
authors.affiliation: Department of Neuroradiology, Centre Hospitalier Sainte-Anne, Paris, France.
authors.forename: A M G
authors.initials: AM
authors.lastname: Gonçalves
authors.forename: P
authors.initials: P
authors.lastname: Page
authors.forename: V
authors.initials: V
authors.lastname: Domigo
authors.forename: J-F
authors.initials: JF
authors.lastname: Méder
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
mesh_terms: D000505:Alopecia / Q000188:drug therapy*; D000726:Androgen Antagonists / Q000009:adverse effects*; D003534:Cyproterone / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008579:Meningioma / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D012074:Remission Induction
chemical_list: D000726:Androgen Antagonists; D003534:Cyproterone