title: Nosocomial infections caused by community-associated methicillin-resistant Staphylococcus aureus in Colombia.
abstract: BACKGROUND
  Community-associated methicillin-resistant Staphylococcus aureus strains (CA-MRSA) have emerged as the causative agent of health care-associated infections.
  
  
  METHODS
  An observational and prospective study was carried out in 5 hospitals in Bogotá, Colombia; severe MRSA infections were identified, and their origin led to classification as health care-associated (HA-MRSA), community-associated, or nosocomial infections. MRSA isolates were analyzed by SCCmec, pulsed-field gel electrophoresis, multilocus sequence typing, and virulence factors.
  
  
  RESULTS
  Twenty-six (10.4%) CA-MRSA nosocomial infection-causing strains (eg, USA300) were detected in 250 MRSA infection isolates in mainly primary bacteremia and surgical site infections. The mortality related to nosocomial infection by CA-MRSA was 27%.
  
  
  CONCLUSIONS
  The presence of nosocomial infection by CA-MRSA in Colombia was confirmed.
authors.affiliation: Departamento de Enfermedades Infecciosas, Facultad de Medicina, UNISANITAS, Clinica Reina Sofia, Bogotá, Colombia. calvarem@gmail.com
authors.forename: Carlos Arturo
authors.initials: CA
authors.lastname: Alvarez
authors.forename: Nancy
authors.initials: N
authors.lastname: Yomayusa
authors.forename: Aura Lucia
authors.initials: AL
authors.lastname: Leal
authors.forename: Jaime
authors.initials: J
authors.lastname: Moreno
authors.forename: Sebastian
authors.initials: S
authors.lastname: Mendez-Alvarez
authors.forename: Milciades
authors.initials: M
authors.lastname: Ibañez
authors.forename: Natasha
authors.initials: N
authors.lastname: Vanegas
mesh_terms: D000328:Adult; D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D003105:Colombia / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D016172:DNA Fingerprinting; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000302:isolation & purification*; D008875:Middle Aged; D017720:Molecular Epidemiology; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D037521:Virulence Factors / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D037521:Virulence Factors