title: [A case of advanced gastric cancer with paraaortic lymph node recurrence reaching a long-term survival by S-1 chemotherapy].
abstract: A 55-year-old male patient with epigastralgia was diagnosed as type 3 gastric cancer at the lower gastric region. Total gastrectomy and D3 lymph node dissection were performed in our hospital. Pathological findings showed pT2N2M0, pStage IIIA. He was treated with 5'-DFUR and PSK therapy as adjuvant chemotherapy for 18 months after surgery. At 24 months after the operation, paraaortic lymph node recurrence was confirmed by computed tomography. He was treated with single agent S-1 in 10 courses on a 4-week dosing regimen with a 2-week interval. After 4 courses, CT showed a disappearance of paraaortic lymph node. He was obtained a complete response. Now the patient is disease-free for 11 years after operation.
authors.affiliation: Department of Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital.
authors.forename: Hideki
authors.initials: H
authors.lastname: Matsumura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Manabu
authors.initials: M
authors.lastname: Ohashi
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iwanaga
authors.forename: Keiichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Nakano
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D001012:Aorta, Abdominal; D017024:Chemotherapy, Adjuvant; D004338:Drug Combinations; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010094:Oxonic Acid / Q000008:administration & dosage*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000008:administration & dosage*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid