title: [Colorectal cancer in Krapina-Zagorje County: the Zabok General Hospital experience].
abstract: OBJECTIVE
  To analyze data and current experience in diagnosing and treating colorectal cancer at Zabok General Hospital in Krapina-Zagorje County during a 5-year period (2002-2006).
  
  
  METHODS
  Retrospective study of 265 cases of colorectal carcinoma treated at Departments of Internal Medicine and of Abdominal Surgery, Zabok General Hospital, and analysis of epidemiological data obtained from the Croatian Public Health Institute for this County.
  
  
  RESULTS
  The incidence rate of this malignancy in Krapina-Zagorje County was between 47.8 and 52 per 100 000, which puts our County at the bottom of the list of all Croatian counties. During the study period, the incidence rate was on a decrease and mortality rate increased, which could be attributed to the late diagnosis of this malignancy (3 months of the occurrence of the first alarming symptoms). Most patients were men, average age 68. The most common symptoms were rectal bleeding, abdominal pain, anemia and changes in defecation habits. The average hospitalization was 13 and 17 days at Departments of Internal Medicine and of Abdominal Surgery, respectively. The most common tumor seats were rectum and sigmoid colon. Colorectal cancer was mostly diagnosed in an advanced stage of disease. More than one third of patients (35.2%) were admitted to the hospital with bowel obstruction or perforation. According to Duke's classification, most patients were in stage C (39.5%), D (22.7%) and A (6.9%). Histologic studies revealed adenocarcinoma in all but one case that proved to be lymphoma.
  
  
  CONCLUSIONS
  We conclude that Zabok General Hospital has valuable experience in diagnosing and treatment of colorectal cancer, with high rank performance since 68.0% of patients from Krapina-Zagorje County are managed at this hospital.
authors.affiliation: Department of Internal Medicine, Zabok General Hospital, Bracak, Croatia. zglumpak@inet.hr
authors.forename: Zvonimir
authors.initials: Z
authors.lastname: Glumpak
authors.forename: Marija
authors.initials: M
authors.lastname: Zlojtro
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Mihaldinec
authors.forename: Tomislav
authors.initials: T
authors.lastname: Pesek
authors.forename: Cvetko
authors.initials: C
authors.lastname: Lez
authors.forename: Anto
authors.initials: A
authors.lastname: Dominković
authors.forename: Ivica
authors.initials: I
authors.lastname: Skrlec
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male