Immune modulation of blood-derived stem cell as a comprehensive tool for treating type 1 diabetes.
Type 1 diabetes (T1D) is an autoimmune disease in which the patient's immune system recognizes their pancreatic islet insulin-producing cells and destroys them. To cure T1D in a comprehensive manner, not only must the islet cells be replaced, the patient's immune system must also be properly regulated mostly in the form of suppression. Blood-derived new stem cells have shown promise in both aspects of this treatment.
Zhao
Yong
Y
Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA. yongzhao@uic.edu
Hwang
David
D
Guo
Chengshan
C
D000818:Animals; D015551:Autoimmunity / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology* / Q000628:therapy*; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology