title: Lymphadenitis caused by H1N1 vaccination: case report.
abstract: A patient admitted to hospital for a supraclavicular painful mass. Ultrasonography showed soliter lymphadenopathy. He underwent H1N1 vaccination 1 week before this lymphadenopathy developed. Groosly the mass measured 1cmx0.8cmx0.8cm. It was round, yellow to brown, slightly soft. In pathologic examination, we detected edema in capsule of lymph node. The basic architecture was preserved. There was mottled appearance caused by marked proliferation of immunoblasts which were positive with CD 30. Also large, unusual immunoblasts which closely resemble mononuclear hodgkin cells were present. These unusual immunoblasts were positive with CD 30, too. For differential diagnosis, at first we should regard hodgkin lymphoma. We suggested that lymphadenitis may be a side effect of H1N1 vaccination.
authors.affiliation: Selcuk University, Meram Medicine Faculty, Department of Pathology, Akyokus-Konya, Turkey. Electronic address: haticetoy@hotmail.com.
authors.forename: Hatice
authors.initials: H
authors.lastname: Toy
authors.affiliation: Selcuk University, Meram Medicine Faculty, Department of Pathology, Akyokus-Konya, Turkey. Electronic address: denizkarasoy@hotmail.com.
authors.forename: Deniz
authors.initials: D
authors.lastname: Karasoy
authors.affiliation: Selcuk University, Meram Medicine Faculty, Department of Pediatric Infectious Disease, Akyokus-Konya, Turkey. Electronic address: mkeser17@mynet.com.
authors.forename: Melike
authors.initials: M
authors.lastname: Keser
mesh_terms: D003937:Diagnosis, Differential; D006651:Histocytochemistry; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000009:adverse effects*; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000175:diagnosis*; D008297:Male; D009333:Neck / Q000000981:diagnostic imaging; D011859:Radiography; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines