Large adrenal oncocytoma with uncertain malignant potential: case report and review of literature.
OBJECTIVE
To report a case of oncocytoma, a relatively rare adrenal tumor, which most commonly is detected as an adrenal incidentaloma.


METHODS
We present a case report, including laboratory, imaging, and pathologic findings, of a 47-year-old obese woman who had hypertension and an incidentally found large, left adrenal mass.


RESULTS
On the basis of the hormonal evaluation, this mass was a nonsecreting adrenal tumor, which histologically proved to be an oncocytoma with borderline malignant characteristics. A collective analysis of the few cases of adrenal oncocytoma published in the medical literature showed that our case corresponded to the previously published cases in preponderant location (left side) as well as the general size (11.4 cm in the largest dimension) and weight (372 g).


CONCLUSIONS
Adrenal oncocytoma should be included in the differential diagnosis of adrenal incidentalomas, especially if large tumors are detected. In addition, a longterm follow-up is suggested because there are no certain clues about the true potential of this tumor.
Peppa
Melpomeni
M
Endocrine Unit, Second Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Athens University Medical School, Attikon University Hospital, Athens, Greece. molypepa@otenet.gr
Karamitopoulou
Evi
E
Nikolopoulos
Panagiotis
P
Peros
Georgios
G
Economopoulos
Theofanis
T
Raptis
Sotirios A
SA
Hadjidakis
Dimitrios
D
D018249:Adenoma, Oxyphilic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D018246:Adrenocortical Adenoma / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011230:Precancerous Conditions / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed