title: Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes.
abstract: An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven-membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process.
authors.affiliation: Department of Chemistry, University of Louisville, Louisville, Kentucky 40292, USA.
authors.forename: Junbin
authors.initials: J
authors.lastname: Han
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.forename: Gerald B
authors.initials: GB
authors.lastname: Hammond
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D000480:Alkynes; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; D003300:Copper