title: [Calcium antagonists: current and future applications based on new evidence. Calcium channel blockers and EBM].
abstract: Calcium channel blockers are antihypertensive drugs which are prescribed widely for reducing high blood pressures. This is due to confirmed and stable efficacy, small side effects, and less influence on metabolism. Nowadays, many clinical trials, studies have proven that calcium channel blockers strongly reduce high blood pressure, prevent cardiovascular disease and stroke, and regress left ventricular hypertrophy. Some studies suggest that they are as beneficial as ACE inhibitors, angiotensin II receptor blockers, and diuretics.
authors.affiliation: Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
authors.forename: Ayumi
authors.initials: A
authors.lastname: Toba
authors.forename: Iwao
authors.initials: I
authors.lastname: Kuwajima
mesh_terms: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D002318:Cardiovascular Diseases / Q000517:prevention & control; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000517:prevention & control; D020521:Stroke / Q000517:prevention & control
chemical_list: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers