Synthesis of a tetrasaccharide related to the O-antigen from Azospirillum lipoferum SR65.
Concise synthesis of a tetrasaccharide repeating unit of the LPS isolated from Azospirillum lipoferum SR65 has been accomplished through suitable protecting group manipulations and stereoselective glycosylation starting from commercially available L-rhamnose and D-glucose. The target oligosaccharide in the form of its p-methoxyphenyl glycoside is suitable for further glycoconjugate formation via selective cleavage of the OMP glycoside. Plant growth-promoting bacteria (PGPB) of genus Azospirillum plays important roles in the growth and development of plants. The interaction between the roots of the plants and the microbes is governed by the cell surface carbohydrate polymers (CPS, LPS, etc.). The present synthetic-based study elucidates aspects of plant-microbe interaction and future biofertiliser design.
Verma
Prashant Ranjan
PR
Indian Institute of Science Education and Research-Kolkata (IISER-K), Mohanpur Campus, PO BCKV Campus Main Office, Mohanpur, Nadia, West Bengal, India.
Mukhopadhyay
Balaram
B
D016949:Azospirillum / Q000235:genetics; D042081:Azospirillum lipoferum / Q000737:chemistry*; D002240:Carbohydrate Sequence; D008969:Molecular Sequence Data; D019081:O Antigens / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis*; D063245:Plant Development
D019081:O Antigens; D009844:Oligosaccharides