Large Brachial Artery Diameter and Metabolic Syndrome in postmenopausal women.
OBJECTIVE
To investigate on Brachial Artery Diameter enlargement in postmenopausal women with Metabolic Syndrome.


METHODS
294 women were admitted and classified in two groups according to the presence of Metabolic Syndrome. Serum glucose, insulin, lipid profile, carotid arteries and Brachial Artery Diameter were measured.


RESULTS
Subjects with Metabolic Syndrome had the following different parameters in comparison to subjects without Metabolic Syndrome: Brachial Artery Diameter, Common Carotid Artery Diameter, IMT, and age. In a multivariate regression analysis Brachial Artery Diameter resulted correlated to age and presence of Metabolic Syndrome, among the Metabolic Syndrome components HDL was the only one to be associated to artery diameter. Furthermore, artery diameters increased with the increasing number of Metabolic Syndrome components.


CONCLUSIONS
Brachial Artery Diameter enlargement was found in postmenopausal women with Metabolic Syndrome. Arterial enlargement seems to be a systemic process occurring in response to some factors involved in atherosclerosis and not a focal change.
Montalcini
Tiziana
T
Human Nutrition Unit, Department of Clinical and Experimental Medicine, University of Catanzaro, Italy. tmontalcini@unicz.it
Gorgone
Gaetano
G
Gazzaruso
Carmine
C
Garzaniti
Adriana
A
Pujia
Arturo
A
D000368:Aged; D050197:Atherosclerosis / Q000473:pathology; D001786:Blood Glucose / Q000378:metabolism; D001916:Brachial Artery / Q000033:anatomy & histology / Q000473:pathology*; D002339:Carotid Arteries / Q000473:pathology; D008078:Cholesterol, LDL / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008593:Menopause; D024821:Metabolic Syndrome / Q000473:pathology*; D008875:Middle Aged; D017698:Postmenopause; D011379:Prognosis; D012044:Regression Analysis
D001786:Blood Glucose; D008078:Cholesterol, LDL