title: Pericardial effusion in atrial fibrillation ablation: a comparison between cryoballoon and radiofrequency pulmonary vein isolation.
abstract: OBJECTIVE
  Atrial fibrillation (AF) ablation is increasingly being performed in electrophysiology laboratories. Pericardial effusion (PE) is certainly one of the most frequently observed complications during AF ablation. The aim of our study was to investigate the incidence and outcome of PE following cryothermal energy balloon ablation (CBA) in comparison with conventional circumferential pulmonary vein isolation with a focal radiofrequency (RF) catheter.
  
  
  RESULTS
  A total of 133 consecutive patients (105 males) with paroxysmal AF were included in this study. Forty-six patients (36 males) underwent CBA (Arctic Front, Medtronic, USA) and 87 (69 males) point-by-point RF ablation guided by electroanatomical mapping (Carto, Biosense Webster, Diamond Bar, CA, USA). Ablation was performed under general anaesthesia with both techniques. All patients underwent a 2D transthoracic echocardiogram within 24 h before and after the procedure as routinely performed in our centre. Pericardial effusion was detected in 19 (14.2%) of 133 patients. Sixteen patients presented mild effusion, one moderate effusion, and two pericardial tamponades. There was no significant difference in the incidence of PE between the cryoballoon and the RF group (11 vs. 16%). A longer procedural time, coronary artery disease, and arterial hypertension were found to be independent predictors of PE during AF ablation.
  
  
  CONCLUSIONS
  Pericardial effusion occurred in a similar proportion following CBA and RF ablation for AF. Pericardial effusion was mostly mild and asymptomatic, with benign clinical outcome not requiring additional hospitalization days.
authors.affiliation: Heart Rhythm Management Centre, UZ Brussel-VUB, Laarbeeklaan 101, 1090 Brussels, Belgium. gbchier@yahoo.it
authors.forename: Gian Battista
authors.initials: GB
authors.lastname: Chierchia
authors.forename: Lucio
authors.initials: L
authors.lastname: Capulzini
authors.forename: Steven
authors.initials: S
authors.lastname: Droogmans
authors.forename: Antonio
authors.initials: A
authors.lastname: Sorgente
authors.forename: Andrea
authors.initials: A
authors.lastname: Sarkozy
authors.forename: Andreas
authors.initials: A
authors.lastname: Müller-Burri
authors.forename: Gaetano
authors.initials: G
authors.lastname: Paparella
authors.forename: Carlo
authors.initials: C
authors.lastname: de Asmundis
authors.forename: Yoshinao
authors.initials: Y
authors.lastname: Yazaki
authors.forename: Dirk
authors.initials: D
authors.lastname: Kerkhove
authors.forename: Guy
authors.initials: G
authors.lastname: Van Camp
authors.forename: Pedro
authors.initials: P
authors.lastname: Brugada
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000601:surgery*; D002305:Cardiac Tamponade / Q000453:epidemiology / Q000209:etiology; D017115:Catheter Ablation / Q000009:adverse effects* / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000453:epidemiology; D003452:Cryosurgery / Q000009:adverse effects* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000453:epidemiology / Q000209:etiology*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D011667:Pulmonary Veins / Q000601:surgery; D012307:Risk Factors; D016896:Treatment Outcome