title: Onychomycosis caused by Fusarium solani in a woman with diabetes.
abstract: A case of untreated fusarial onychomycosis leading to serious consequences is reported. Fusarium solani is a widespread fungus and an occasional human pathogen. It usually invades rapidly in immunocompromised hosts, and often results in a poor outcome despite treatment. We report a woman with diabetes mellitus who had untreated fusarial infection of the nails, which developed into subcutaneous fusariosis, superinfected by bacteria, and then evolved into osteomyelitis that subsequently resulted in septic shock. Early management of mycotic nails in immunocompromised hosts is crucial to prevent life-threatening disease.
authors.affiliation: Department of Dermatology, Kaoshiung Medical University Hospital, Kaoshiung, Taiwan.
authors.forename: C Y
authors.initials: CY
authors.lastname: Wu
authors.forename: G S
authors.initials: GS
authors.lastname: Chen
authors.forename: C C E
authors.initials: CC
authors.lastname: Lan
mesh_terms: D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D048909:Diabetes Complications / Q000382:microbiology*; D017719:Diabetic Foot / Q000382:microbiology*; D005260:Female; D005670:Fusarium / Q000302:isolation & purification*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D014009:Onychomycosis / Q000188:drug therapy / Q000382:microbiology*; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole