title: [Changes in liver function and immune function following laparoscopic and traditional open cholecystectomy: a comparative study].
abstract: OBJECTIVE
  To compare the effect of laparoscopic cholecystectomy (LC) and open cholecystectomy (OC) on liver function and immune function.
  
  
  METHODS
  Forty-two patients with normal liver function underwent LC (n=21) or OC (n=21) according to the patients' preference. One day before and 7 days after the operations, the liver functions (ALT, AST, TBIL, ALB) and immune functions (CD3, CD4, CD8, NK cell percentage, IgA, IgM, IgG and C3, C4) of the patients were measured.
  
  
  RESULTS
  No statistical differences were found in the liver functions or immune functions between the two groups after the operation.
  
  
  CONCLUSIONS
  LC and OC show no significant difference in the effects on the liver function and immune function.
authors.affiliation: Department of Surgery, 457 Hospital of PLA, Wuhan 430012, China. wuchundong1974@163.com
authors.forename: Chun-dong
authors.initials: CD
authors.lastname: Wu
authors.forename: Dong
authors.initials: D
authors.lastname: Zuo
mesh_terms: D000328:Adult; D000917:Antibody Formation / Q000276:immunology; D002763:Cholecystectomy; D017081:Cholecystectomy, Laparoscopic; D002769:Cholelithiasis / Q000276:immunology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005706:Gallbladder Neoplasms / Q000276:immunology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007109:Immunity; D007694:Killer Cells, Natural / Q000276:immunology; D008099:Liver / Q000503:physiopathology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000276:immunology / Q000503:physiopathology / Q000601:surgery