title: [Primary study of diagnosis and treatment of huge petrous apex cholesteatoma (clinical analysis of 2 cases)].
abstract: OBJECTIVE
  To investigate the clinical features, operative approach and method of petrous apex cholesteatoma, to improve the effect of operation and to reduce surgical complications.
  
  
  METHODS
  Two cases of patients with giant petrous apex cholesteatoma were treated by trans labyrinth approach, one of which was successfully operated with oto-endoscope-assisted surgery.
  
  
  RESULTS
  No cerebrospinal fluid leakage, infection, vertigo or disequilibrium was found in the two cases after operation.
  
  
  CONCLUSIONS
  Temporal CT and MRI are of great importance in clinical diagnosis and choice of surgical approach. Surgery by trans-labyrinth approach paves way for removing cholesteatoma thoroughly, dealing with facial nerve and repairing cerebrospinal fluid leakage. Surgery is considered to be the only way to cure petrous apex cholesteatoma, while the key procedure to prevent recurrence lies in complete removal of lesion, long-time strict follow up and regular clearance of the surgical field.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Foshan Hospital Affiliated to Zhong-shan University, the First People's Hospital of Foshan, Foshan, 528000, China. lfeng@fsyyy.com
authors.forename: Feng
authors.initials: F
authors.lastname: Lin
authors.forename: Yuejian
authors.initials: Y
authors.lastname: Wang
authors.forename: Youjun
authors.initials: Y
authors.lastname: Yu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liu
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Yu
mesh_terms: D002781:Cholesteatoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010579:Petrous Bone / Q000473:pathology*; D014057:Tomography, X-Ray Computed