Constituents of Trigonostemon chinensis.
Phytochemical investigation on the stem bark and wood of Trigonostemon chinensis led to the isolation of four new dinorditerpenoids, trigonostemons A-D (1, 3, 5, 6), a new phenanthrenone, trigonostemon E (7), and a new bisindole alkaloid, trigonostemon F (8). The structures were established by extensive spectroscopic methods. The absolute configurations of 1-6 were determined by X-ray crystallography, circular dichroism, quantum chemical TDDFT calculations, and chemical transformations. The relative configuration of 8 was confirmed by X-ray diffraction analysis.
Zhu
Qin
Q
State Key Laboratory of Drug Research & Department of Natural Products Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
Tang
Chun-Ping
CP
Ke
Chang-Qiang
CQ
Li
Xi-Qiang
XQ
Liu
Jin
J
Gan
Li-She
LS
Weiss
Hans-Christoph
HC
Gesing
Ernst-Rudolf
ER
Ye
Yang
Y
D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D026121:Indole Alkaloids; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification*; D024301:Plant Bark / Q000737:chemistry; D014934:Wood / Q000737:chemistry
D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D026121:Indole Alkaloids; D010616:Phenanthrenes; C546759:trigonostemon E; C546758:trigonostemon F