title: [Comparative efficacy of two topical formulations containing 10% fipronil on the control of Ctenocephalides felis felis on cats].
abstract: The goal of the present study was to evaluate the comparative efficacy of two topical formulations containing 10% fipronil on the control of Ctenocephalides felis felis on cats. The trial was performed at the Laboratory of Experimental Chemotherapy in Veterinary Parasitology from the Department of Animal Parasitology of the Institute of Veterinary of the Universidade Federal Rural do Rio de Janeiro. Eighteen mixed-breed cats were divided in three groups of six animals each. One group remained without treatment (control). The other groups received as treatment the two topical formulations, a commercial reference and the novel one, both containing 10% fipronil. Treated animals received 0.5 mL of product along their cervical region. Cats were infested on days - 2, +5, +12, +19, +26 and +33. Evaluations were made using the "comb test". The first one was undertaken 4 days after the initial infestation (day +2), and others 48 hours after following infestations (days +7, +14, +21, +28 and + 35). Both tested formulations had satisfactory efficacy until day + 35. No differences were observed comparing the efficacy levels between both formulations throughout the experimental period. The novel topical 10% fipronil formulation presented desirable efficacy on the control of C. f. felis on cats.
authors.affiliation: Departamento de Parasitologia Animal, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Michelle Godan de Freitas
authors.initials: MG
authors.lastname: Tancredi
authors.forename: Thaís Ribeiro
authors.initials: TR
authors.lastname: Correia
authors.forename: Francisco de Assis
authors.initials: Fde A
authors.lastname: Ribeiro
authors.forename: Maria Clara da Silva Negreiros
authors.initials: MC
authors.lastname: Botelho
authors.forename: Pedro Vianna
authors.initials: PV
authors.lastname: Tavares
authors.forename: Fabio Barbour
authors.initials: FB
authors.lastname: Scott
authors.forename: Guilherme Gomes
authors.initials: GG
authors.lastname: Verocai
authors.forename: Katherina
authors.initials: K
authors.lastname: Coumendouros
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002371:Cat Diseases / Q000517:prevention & control*; D002415:Cats; D004478:Ectoparasitic Infestations / Q000517:prevention & control / Q000662:veterinary*; D007306:Insecticides / Q000008:administration & dosage*; D011720:Pyrazoles / Q000008:administration & dosage*; D005423:Siphonaptera
chemical_list: D007306:Insecticides; D011720:Pyrazoles; C082360:fipronil