title: My doctor recommended I take methotrexate to relieve the pain of the rheumatoid arthritis I have in my shoulder. But I've heard that methotrexate can cause liver problems. How will I know if I'm developing liver problems?
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D012307:Risk Factors; D020069:Shoulder Pain / Q000188:drug therapy* / Q000209:etiology
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate