title: [Case report of infected pseudo-aneurysm after intra-arterial chemotherapy].
abstract: A 63-year-old man admitted to emergency center of our hospital with fever and obstructive jaundice. Computed tomography (CT) showed a mass in the head of the pancreas and a dilated bile duct. After performing preoperative biliary drainage, we conducted pancreatico-duodenectomy (PD-II: T3, N1, stage III). As adjuvant chemotherapy, the patient received a hepatic arterial infusion with 5-FU to prevent liver metastasis. A catheter was placed in the right femoral artery and intra-arterial chemotherapy was carried out for one week. After the completion of chemotherapy, swelling and redness of the right inguinal region was observed. CT revealed an infected pseudo-aneurysm of the femoral artery. Despite intravenous antibiotic therapy for 2 days, bleeding and pus discharge at the catheter root were observed. He immediately underwent drainage and primary suture to stop the bleeding. Two weeks after surgery for the infected pseudo-aneurysm, a right external iliac-femoral bypass operation was performed. Five weeks after surgery, he was discharged without further incident. In such cases, it is advisable to drain the infected pseudo-aneurysm following a prompt diagnosis, and perform a secondary bypass operation.
authors.affiliation: Department of Gastroenterological Surgery, Iseikai Hospital.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Tanigawa
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Hasuike
authors.forename: Masaharu
authors.initials: M
authors.lastname: Yamada
authors.forename: Syouji
authors.initials: S
authors.lastname: Fujiwara
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Murata
mesh_terms: D017541:Aneurysm, False / Q000209:etiology*; D000785:Aneurysm, Infected / Q000209:etiology*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D005263:Femoral Artery; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000628:therapy
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil