Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids.
OBJECTIVE
To assess the effect on FSH of the application of different types of uterine vessel blockage (uterine artery occlusion alone [UAO] or with blockage of vessel anastomosis [UVO]) in the management of women with fibroids.


METHODS
Case-control study.


METHODS
Medical center.


METHODS
One hundred ten women with uterine fibroids.


METHODS
Forty-four consecutive patients undergoing UAO were compared with 66 matched subjects who underwent UVO during the same period.


METHODS
Surgery types and FSH levels were compared.


RESULTS
At the first month after surgery, FSH levels were elevated from 5.5 mIU/mL to 14.2 and 8.7 mIU/mL in the UVO and UAO groups, respectively. The difference between the 2 groups continued up to 6 months and disappeared thereafter. More patients (38%) in the UVO group had an increased FSH level of >10 mIU/mL, compared with 5% in the UAO group at the first month after surgery, which contributed to the high percentage of women with irregular menstruation.


CONCLUSIONS
Women treated with UVO were associated with a greater risk of a significant increase in FSH level at the first month after operation than those treated with UAO, which may be a reflection of diminished ovarian function. The long-term effect was uncertain, because of the lack of difference in the FSH levels between the two groups.
Lee
Wen-Ling
WL
Institute of Clinical Medicine, Institute of Biochemistry, National Yang-Ming University School of Medicine, and Department of Medicine, Cheng-Hsin General Hospital, Taipei, Taiwan.
Liu
Wei-Min
WM
Fuh
Jong-Ling
JL
Tsai
Ying-Chieh
YC
Shih
Chun Che
CC
Wang
Peng-Hui
PH
D000328:Adult; D000714:Anastomosis, Surgical / Q000145:classification / Q000379:methods / Q000534:rehabilitation; D016022:Case-Control Studies; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods / Q000534:rehabilitation; D007889:Leiomyoma / Q000097:blood / Q000098:blood supply / Q000601:surgery*; D055988:Uterine Artery / Q000601:surgery*; D055357:Uterine Artery Embolization / Q000379:methods / Q000534:rehabilitation; D014594:Uterine Neoplasms / Q000097:blood / Q000098:blood supply / Q000601:surgery*; D014599:Uterus / Q000098:blood supply / Q000601:surgery*
D005640:Follicle Stimulating Hormone