title: Is there an association between Helicobacter pylori in the inlet patch and globus sensation?
abstract: OBJECTIVE
  To determine the association between Helicobacter pylori (H. pylori) and globus sensation (GS) in the patients with cervical inlet patch.
  
  
  METHODS
  Sixty-eight patients with esophageal inlet patches were identified from 6760 consecutive patients undergoing upper gastrointestinal endoscopy prospectively. In these 68 patients with cervical inlet patches, symptoms of globus sensation (lump in the throat), hoarseness, sore throat, frequent clearing of the throat, cough, dysphagia, odynophagia of at least 3 mo duration was questioned prior to endoscopy.
  
  
  RESULTS
  Cervical heterotopic gastric mucosa (CHGM) was found in 68 of 6760 patients. The endoscopic prevalence of CHGM was determined to be 1%. H. pylori was identified in 16 (23.5%) of 68 patients with inlet patch. Fifty-three patients were classified as CHGM II. This group included 48 patients with globus sensation, 4 patients with chronic cough and 1 patient with hoarseness. All the patients who were H. pylori (+) in cervical inlet patches had globus sensation.
  
  
  CONCLUSIONS
  Often patients with CHGM have a long history of troublesome throat symptoms. We speculate that disturbances in globus sensation are like non-ulcer dyspepsia.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Gazi University Hospital, Ankara 06500, Turkey. hakanalagozlu@gmail.com
authors.forename: Hakan
authors.initials: H
authors.lastname: Alagozlu
authors.forename: Zahide
authors.initials: Z
authors.lastname: Simsek
authors.forename: Selahattin
authors.initials: S
authors.lastname: Unal
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cindoruk
authors.forename: Sukru
authors.initials: S
authors.lastname: Dumlu
authors.forename: Ayse
authors.initials: A
authors.lastname: Dursun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002828:Choristoma / Q000150:complications*; D016099:Endoscopy, Gastrointestinal; D004935:Esophageal Diseases / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D050782:Esophageal pH Monitoring; D005260:Female; D005753:Gastric Mucosa; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000209:etiology* / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D015995:Prevalence; D011446:Prospective Studies; D012677:Sensation; D012720:Severity of Illness Index; D055815:Young Adult