[A case of chemo-radiation therapy with high degree of efficacy for esophageal cancer with liver metastasis].
A 78-year-old man underwent a radical resection for esophageal cancer (Stage III) and cardiac gastric cancer (Stage IA) at another hospital 2 years ago. After the operation, he was followed at that hospital. In 2008, abdominal CT scan and FDG-PET/CT revealed a liver tumor. He was referred to our hospital and was diagnosed as esophageal cancer with liver metastasis. He received chemo-radiation therapy (CRT). The regimen was docetaxel hydrate (30 mg/m2, day 1, 8, 29 and 36) and S-1 (60 mg/m2, day 1-14 and day 29-45) with radiation (45 Gy) for liver metastasis. He finished the CRT without any hematotoxicity, liver disorder and non-hematotoxic adverse event (grade 3). Abdominal CT was done 2 months after the end of CRT and revealed that the tumor lesion disappeared completely. The patient is alive for 11 months after the CRT without any evidence of recurrence. The tumor disappeared completely for the last 11 months. We conclude that CRT is safe and very effective for esophageal cancer with liver metastasis.
Kubota
Hisako
H
Department of Gastroenterological Surgery, Kawasaki Medical School.
Matsumoto
Hideo
H
Saito
Ai
A
Kaida
Yuko
Y
Murakami
Haruaki
H
Higashida
Masaharu
M
Hirabayashi
Yoko
Y
Oka
Yasuo
Y
Okumura
Hideo
H
Uragami
Atsushi
A
Yamashita
Kazuki
K
Hirai
Toshihiro
T
Yoden
Eisaku
E
Hiratsuka
Junichi
J
D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004338:Drug Combinations; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy*; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
D000970:Antineoplastic Agents; D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid