The adenosine wedge: a new structural motif in ribosomal RNA.
Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary structure of the motif.
Gagnon
Matthieu G
MG
Departement de Biochimie, Universite de Montreal, Montreal, Quebec H3C 3J7, Canada.
Steinberg
Sergey V
SV
D000241:Adenosine / Q000737:chemistry*; D001483:Base Sequence; D004926:Escherichia coli / Q000737:chemistry / Q000235:genetics; D008958:Models, Molecular; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D012329:RNA, Bacterial / Q000737:chemistry / Q000235:genetics; D012335:RNA, Ribosomal / Q000737:chemistry* / Q000235:genetics
D012329:RNA, Bacterial; D012335:RNA, Ribosomal; D000241:Adenosine