Effect of endemic fluorosis on hematological parameters.
Although so many studies exist on effect of fluoride on hematological parameters in experimental animals, a few studies have been conducted to investigate the effects of chronic fluorosis on hematological parameters in humans' subjects with endemic fluorosis. So we aimed to determine the hematological parameters in patients with endemic fluorosis. The study group consisted of 60 patients with endemic fluorosis (27 females, 33 males, and mean age 33.4 ± 9.6 years). An age-, gender-, and body mass index-matched control group was composed of 34 healthy volunteers (11 females, 23 males with a mean age 32.6 ± 5.6 years). Urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (0.42 ± 0.09 vs 1.92 ± 0.14 mg/l, respectively; P < 0.001). There were no statistically significant differences between the fluorosis group and control group with respect to hematological parameters (complete blood count and ferritin). We concluded that chronic fluorosis has no effect on hematological parameters in patients with endemic fluorosis.
Ersoy
Ismail Hakki
IH
Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Suleyman Demirel University, Cunur, 32200 Isparta, Turkey.
Alanoglu
E Guçhan
EG
Koroglu
Banu Kale
BK
Varol
Simge
S
Akcay
Selahaddin
S
Ugan
Yunus
Y
Ersoy
Sıddıka
S
Tamer
Mehmet Numan
MN
D000328:Adult; D019353:Endemic Diseases; D005260:Female; D005459:Fluorides / Q000097:blood* / Q000652:urine*; D009050:Fluorosis, Dental / Q000097:blood* / Q000652:urine; D006801:Humans; D008297:Male
D005459:Fluorides