title: Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity.
abstract: Stereoselective syntheses of daedalin A and quercinol, an enantiomer of daedalin A, is described. The tyrosinase inhibitory activities of daedalin A and quercinol were examined. The activity of quercinol was weaker than that of daedalin A at high concentration.
authors.affiliation: Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University, 8304 Minami-minowa, Kami-ina, Nagano 399-4598, Japan.
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Sekimoto
authors.forename: Yasunao
authors.initials: Y
authors.lastname: Hattori
authors.forename: Keiji
authors.initials: K
authors.lastname: Morimura
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Hirota
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Makabe
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010940:Plant Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D001578:Benzopyrans; D010940:Plant Proteins; C526356:daedalin A; C520998:quercinol; D014442:Monophenol Monooxygenase