O-acetyl oximes as transformable directing groups for Pd-catalyzed C-H bond functionalization.
O-Acetyl oximes serve as effective directing groups for Pd-catalyzed sp(2) and sp(3) C-H functionalization reactions. The C-H functionalization products can be subsequently transformed into ortho- or beta-functionalized ketones, alcohols, amines, and heterocycles.
Neufeldt
Sharon R
SR
Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, USA.
Sanford
Melanie S
MS
D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D010091:Oximes / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D000085:Acetates; D010091:Oximes; D010165:Palladium