Identification of a novel HLA-DRB3*01 variant, HLA-DRB3*0114, containing a DRB1 sequence motif by micro-temperature gradient gel electrophoresis confirmed by sequence-based typing.
A novel human leukocyte antigen (HLA)-DRB3*01 allele carrying a HLA-DRB1-specific sequence motive in exon 2 is described.
Garritsen
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Institute for Clinical Transfusion Medicine, Städtisches Klinikum Braunschweig gGmbH, Braunschweig, Germany. h.garritsen@klinikum-braunschweig.de
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Legath
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Hannig
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Fischer
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D000483:Alleles; D001483:Base Sequence; D019411:Clinical Laboratory Techniques; D004586:Electrophoresis / Q000379:methods; D005091:Exons; D005782:Gels; D006684:HLA-DR Antigens / Q000737:chemistry* / Q000235:genetics; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D013696:Temperature
D005782:Gels; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains