Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity.
Stereoselective syntheses of daedalin A and quercinol, an enantiomer of daedalin A, is described. The tyrosinase inhibitory activities of daedalin A and quercinol were examined. The activity of quercinol was weaker than that of daedalin A at high concentration.
Sekimoto
Mitsuo
M
Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University, 8304 Minami-minowa, Kami-ina, Nagano 399-4598, Japan.
Hattori
Yasunao
Y
Morimura
Keiji
K
Hirota
Mitsuru
M
Makabe
Hidefumi
H
D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010940:Plant Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D001578:Benzopyrans; D010940:Plant Proteins; C526356:daedalin A; C520998:quercinol; D014442:Monophenol Monooxygenase