[Compatibility chemistry of acid-alkaline pair medicine of Dahuang and Huangbai in Dahuang Xiaoshi decoction].
OBJECTIVE
To determine the change pattern of alkaline and acid components of Dahuang and Huangbai amoung different combinations in Dahuang Xiaoshi decotion.


METHODS
The contents of anthraquinones and berberine were determined by HPLC in samples of Dahuang extracts, Huangbai extracts, Dahuang and Huangbai pair medicine extracts, and extracts of whole recipe.


RESULTS
The contents of anthraquinones and berberine were decreased with the changes of combinations: from component medicinal material alone to pair medicines, and to whole recipe. the change pattern was more apparent in water decoctions than in ethanol extracts.


CONCLUSIONS
The contents of alkaline and acid components are changed with different extract methods and different combinations.
Pei
Miaorong
M
Department of Chinese Materia Medica, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China. peimr602@163.com
Duan
Xiujun
X
Pei
Xiangping
X
D000143:Acids / Q000032:analysis; D000468:Alkalies / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D032102:Phellodendron / Q000737:chemistry*; D012250:Rheum / Q000737:chemistry*
D000143:Acids; D000468:Alkalies; D004365:Drugs, Chinese Herbal