title: A two-photon fluorescent probe for thiols in live cells and tissues.
abstract: We report a two-photon fluorescent probe (ASS) that can be excited by 780 nm femtosecond pulses and detect thiols in live cells and living tissues at a 90-180 microm depth without interference from other biologically relevant species by two-photon microscopy.
authors.affiliation: Department of Chemistry, Korea University, 1-Anamdong, Seoul, 136-701, Korea.
authors.forename: Jun Han
authors.initials: JH
authors.lastname: Lee
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.forename: Yu Shun
authors.initials: YS
authors.lastname: Tian
authors.forename: Ji Hee
authors.initials: JH
authors.lastname: Han
authors.forename: Bong Rae
authors.initials: BR
authors.lastname: Cho
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008744:Methylamines / Q000737:chemistry; D008856:Microscopy, Fluorescence; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry; D017785:Photons; D051381:Rats; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: C548238:2-methylamino-6-acetylnaphthalene; D005456:Fluorescent Dyes; D008744:Methylamines; D009281:Naphthalenes; D013438:Sulfhydryl Compounds