title: Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
abstract: Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.
authors.affiliation: Department of Psychiatry, UIC Psychiatric Institute MC912, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL 60612, USA.
authors.forename: Neil R
authors.initials: NR
authors.lastname: Smalheiser