title: Comparison of dual-source CT coronary angiography and conventional coronary angiography for detecting coronary artery disease.
abstract: To evaluate the diagnostic accuracy of dual-source CT coronary angiography for detecting coronary artery stenosis. From February 2008 to January 2009, dual-source CT coronary CT angiography (DSCT-CCTA) and conventional coronary angiography (CAG) were both performed in 84 patients who had either clinical symptoms or a high risk of coronary artery disease. The diagnostic accuracy of DSCT-CCTA was evaluated by comparing it with that of CAG, which was regarded as the gold standard for making the diagnosis of coronary artery disease. Occlusion or stenosis of various degrees was revealed by DSCT-CCTA in 244 segments of 84 patients. Compared to CAG, segment-based sensitivity, specificity, positive predictive value and negative predictive value of DSCT-CCTA were 97.4, 97.8, 92.2 and 100%, respectively. The diagnostic accuracy of DSCT-CCTA for the detection of coronary artery stenosis was 96.5%. The paired chi2 tests revealed no significant difference between DSCT-CCTA and CAG for making the diagnosis of coronary artery disease (P = 0.076). The diagnostic performance of DSCT-CCTA is generally as accurate as that of CAG. Thus, DSCT-CCTA is a reliable non-invasive method for detecting coronary artery stenosis.
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xu
authors.forename: Lijun
authors.initials: L
authors.lastname: Tang
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Zhu
authors.forename: Hai
authors.initials: H
authors.lastname: Xu
authors.forename: Jinhua
authors.initials: J
authors.lastname: Tang
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Yang
authors.forename: Liansheng
authors.initials: L
authors.lastname: Wang
authors.forename: Dehang
authors.initials: D
authors.lastname: Wang
mesh_terms: D000368:Aged; D016477:Artifacts; D016009:Chi-Square Distribution; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011857:Radiographic Image Interpretation, Computer-Assisted; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed