title: Value of endobronchial ultrasound in staging non-small cell lung cancer.
abstract: Endobronchial ultrasound guided fine-needle aspiration (EBUS-TBNA) is an accurate, safe and minimally invasive technique for the analysis of mediastinal lymph nodes. The aim of our study was to assess the value of EBUS probe using single-channel bronchoscope. Twenty-two patients who undervent EBUS-TBNA with proven non-small cell lung cancer and enlarged (> 1 cm) mediastinal lymph node at chest computed tomography were retrospectively enrolled in the study. The mean age of the patients was 56.8 + or - 9.0 (45-76), and all of them were men. Mean size of sampled 32 lymph nodes was 19.9 + or - 6.5 mm (10-30). The average number of needle passes was 3.2 + or - 0.9 (1-5). Adequate material was found in 31 (97%) of the lymph nodes. In 15 (68.1%) of the patients lymph node metastasis was detected. Of 7 patients with negative cytology, a mediastinoscopy was done. There were no complications other than minimal hemorrhage. The sensitivity of EBUS-TBNA was calculated as 88.2%, whereas the specificity was 100% and accuracy was found to be 90.9%. EBUS guided TBNA of mediastinal lymph nodes is a safe approach which can be a tool for obtaining adequate material and high diagnostic yield in staging of non-small cell lung cancer.
authors.affiliation: Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. sinemtimur@yahoo.com
authors.forename: Sinem Nedime
authors.initials: SN
authors.lastname: Sökücü
authors.forename: Erdoğan
authors.initials: E
authors.lastname: Cetinkaya
authors.forename: Sedat
authors.initials: S
authors.lastname: Altin
authors.forename: Levent
authors.initials: L
authors.lastname: Karasulu
authors.forename: Ekrem Cengiz
authors.initials: EC
authors.lastname: Seyhan
authors.forename: Akif
authors.initials: A
authors.lastname: Turna
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D001999:Bronchoscopy; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D019160:Endosonography / Q000379:methods; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008481:Mediastinoscopy; D008482:Mediastinum / Q000000981:diagnostic imaging; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional / Q000379:methods*