[The colon cancer patient with multiple hepatic metastases and peritoneal disseminations was treated by hepatic arterial infusion chemotherapy and resection of the metastatic peritoneal dissemination with successive systemic chemotherapy--a case report of the long term survivor].
A 33-year-old man, who underwent ileo-cecal resection and sigmoidectomy for concomitant cecal cancer and sigmoid colon cancer which was diagnosed during the emergent operation for the perforated acute appendicitis, suffered simultaneous multiple hepatic metastases. Postoperative hepatic aerial infusion chemotherapy with 5-FU was done (total dose 63 g), and the metastases were successfully disappeared (CR). Although 16-month passed from the operation, locoregional recurrence at the colorectal anastomosis and peritoneal dissemination were occurred. Aggressive resections of the recurrent sites (anterior resection of the rectum, ileum, ascending colon and other recurrent sites) and successive systemic administration of FOLFOX4(9-course), FOLFIRI (20-course) and capecitabine (15-course) were achieved. The patient survived for 4.5 years after the initial treatment.
Ando
Masayuki
M
Department of Surgery, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital.
Nagahama
Takeshi
T
Fukuda
Akira
A
Ami
Katsunori
K
Hataji
Kenichiro
K
Ohara
Toshiya
T
Ganno
Hideaki
H
Kawasaki
Norihito
N
Tei
Shikofumi
S
Okada
Youichi
Y
D000328:Adult; D002430:Cecal Neoplasms / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D012811:Sigmoid Neoplasms / Q000473:pathology* / Q000628:therapy*