title: [Three cases of biliary tract cancer with positive surgical margin obtained a long-term survival after multimodality therapy].
abstract: We report three cases of biliary tract cancer with positive surgical margin obtained a long-term survival after multimodality therapy. Case 1: A 58-year-old man had operated PPPD for middle part of biliary tract cancer. Final pathological findings revealed HM2. Hepatic metastasis and anastomotic recurrence were observed, postoperatively. RFA and chemoradiation therapy were performed against these lesions. Nevertheless, the patient died of sepsis associated with hepatic abscess caused by cholangitis 5 years and 10 months after surgery. Case 2: A 72-year-old man had operated for upper part of biliary tract cancer. Intra-operative pathological findings revealed HM 2 and DM 2, extra-bile duct resection was performed for this lesion. After surgery, radiation therapy, systemic chemotherapy and hepatic arterial chemotherapy were performed, nevertheless the patient died of cancer 2 years and 6 months after surgery. Case 3: A 75-year-old man had operated for upper part of biliary tract cancer. Intra-operative pathological findings revealed HM 2 and DM 2, an extra-bile duct resection was performed for this lesion. After surgery, chemoradiation therapy, hepatic arterial chemotherapy and systemic chemotherapy were performed, nevertheless the patient died of cancer 3 years and 6 months after surgery.
authors.affiliation: Department of Surgery, Toho University Ohashi Medical Center.
authors.forename: Koji
authors.initials: K
authors.lastname: Asai
authors.forename: Manabu
authors.initials: M
authors.lastname: Watanabe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsukiyo
authors.forename: Akihiro
authors.initials: A
authors.lastname: Osawa
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Saito
authors.forename: Kojiro
authors.initials: K
authors.lastname: Dotai
authors.forename: Osahiko
authors.initials: O
authors.lastname: Hagiwara
authors.forename: Masamichi
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Saida
authors.forename: Shinya
authors.initials: S
authors.lastname: Kusachi
authors.forename: Jiro
authors.initials: J
authors.lastname: Nagao
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Oharaseki
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged