title: Direct visualization of fiber information by coherence.
abstract: OBJECTIVE
  The structure of fiber tracts in DT-MRI data presents a challenging problem for visualization and analysis. We derive visualization of such traces from a local coherence measure and achieve much improved visual segmentation.
  
  
  METHODS
  We introduce a coherence measure defined for fiber tracts. This quantitative assessment is based on infinitesimal deviations of neighboring tracts and allows identification and segmentation of coherent fiber regions. We use a hardware-accelerated implementation to achieve interactive visualization on slices and provide several approaches to visualize coherence information. Furthermore, we enhance existing techniques by combining them with coherence.
  
  
  RESULTS
  We demonstrate our method on both a canine heart, where the myocardial structure is visualized, and a human brain, where we achieve detailed visualization of major and minor fiber bundles in a quality similar to and exceeding fiber clustering approaches.
  
  
  CONCLUSIONS
  Our approach allows detailed and fast visualization of important anatomical structures in DT-MRI data sets.
authors.affiliation: Institute for Data Analysis and Visualization, Department of Computer Science, University of California, Davis, CA, USA. hlawitschka@ucdavis.edu
authors.forename: Mario
authors.initials: M
authors.lastname: Hlawitschka
authors.forename: Christoph
authors.initials: C
authors.lastname: Garth
authors.forename: Xavier
authors.initials: X
authors.lastname: Tricoche
authors.forename: Gordon
authors.initials: G
authors.lastname: Kindlmann
authors.forename: Gerik
authors.initials: G
authors.lastname: Scheuermann
authors.forename: Kenneth I
authors.initials: KI
authors.lastname: Joy
authors.forename: Bernd
authors.initials: B
authors.lastname: Hamann
mesh_terms: D000465:Algorithms; D000818:Animals; D056324:Diffusion Tensor Imaging / Q000379:methods*; D004285:Dogs; D006801:Humans; D008279:Magnetic Resonance Imaging