title: Conversion of atrial flutter to sinus rhythm during landiolol infusion.
abstract: A 73-year-old male patient with a past history of hypertension and atrial premature contraction underwent endoscopic restoration of the left bubonocele. Sinus rhythm was confirmed by preoperative electrocardiography, but paroxysmal atrial flutter developed when abdominoscopy was started. Continuous administration of landiolol hydrochloride at a dose of 0.005 mg kg(-1) min(-1) after a loading dose of 0.04 mg kg(-1) min(-1) for 1 min resulted in control of heart rate without a decrease in blood pressure. Atrial flutter was converted to sinus rhythm 3 min after the start of administration. Landiolol hydrochloride was administered continuously until the morning of the following day and sinus rhythm was maintained postoperatively.
authors.affiliation: Department of Anesthesiology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan. kamome@med.oita-u.ac.jp
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Koji
authors.initials: K
authors.lastname: Goto
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Ohchi
authors.forename: Norihisa
authors.initials: N
authors.lastname: Yasuda
authors.forename: Chihiro
authors.initials: C
authors.lastname: Shingu
authors.forename: Takayuki
authors.initials: T
authors.lastname: Noguchi
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D007262:Infusions, Intravenous; D007431:Intraoperative Complications; D010535:Laparoscopy; D009025:Morpholines / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D009025:Morpholines; C077049:landiolol; D014508:Urea