title: Less than 1% cerebrospinal fluid leakage in 1,803 translabyrinthine vestibular schwannoma surgery cases.
abstract: OBJECTIVE
  To determine the incidence rate of cerebrospinal fluid (CSF) leak after translabyrinthine vestibular schwannoma surgery since the alteration of the surgical procedure. To compare with previous series and other series in literature.
  
  
  METHODS
  Database analysis.
  
  
  METHODS
  Tertiary referral neurotologic private practice.
  
  
  METHODS
  A series of 1,803 patients who underwent translabyrinthine vestibular schwannoma surgery between 1993 and 2009. The result of this group was compared with corresponding series.
  
  
  METHODS
  Translabyrinthine and extended translabyrinthine vestibular schwannoma surgery. Literature review and comparison.
  
  
  METHODS
  Rates of CSF leak in this series and historical perspective of the outcome.
  
  
  RESULTS
  Fifteen patients (0.8%) of 1,803 cases had CSF leaks. The method used since 1993 has shown a significant improvement compared with major case series of the last 10 years.
  
  
  CONCLUSIONS
  The methods used in translabyrinthine vestibular schwannoma surgery in our center can reduce CSF leakage to an absolute minimum. Compared with all large series, this could be a new era of translabyrinthine vestibular schwannoma surgery.
authors.affiliation: Department of Otorhinolaryngology & Head and Neck Surgery, VU University Medical Center, Amsterdam, the Netherlands. P.Merkus@VUmc.nl
authors.forename: Paul
authors.initials: P
authors.lastname: Merkus
authors.forename: Abdelkader
authors.initials: A
authors.lastname: Taibah
authors.forename: Giulio
authors.initials: G
authors.lastname: Sequino
authors.forename: Mario
authors.initials: M
authors.lastname: Sanna
mesh_terms: D000328:Adult; D000368:Aged; D016208:Databases, Factual; D007758:Ear, Inner / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000134:cerebrospinal fluid* / Q000473:pathology / Q000601:surgery*; D013506:Otologic Surgical Procedures / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed