Roles of DNA repair proteins in telomere maintenance.
Telomeres are protected and maintained by telomere-specific proteins. In addition, proteins involved in DNA repair, such as Mre11-Rad50-Nbs1 complex, RPA, and RecQ helicase, are also involved in telomere maintenance. In this review, the roles of these proteins in telomere maintenance and their functional relationships to the telomere-specific proteins will be discussed.
Ueno
Masaru
M
Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, higashi-Hiroshima, Japan. scmueno@hiroshima-u.ac.jp
D000818:Animals; D004260:DNA Repair; D006801:Humans; D011506:Proteins / Q000378:metabolism*; D053484:RecQ Helicases / Q000378:metabolism; D016615:Telomere / Q000235:genetics* / Q000378:metabolism*
D011506:Proteins; D053484:RecQ Helicases