Influence of the preceding dwell time on the peritoneal equilibration test with 3.86% glucose solution in automated peritoneal dialysis.
OBJECTIVE
The peritoneal equilibration test (PET) using 3.86% glucose solution is preceded by a long dwell with 3.86% glucose solution. A point of concern in patients treated with automated peritoneal dialysis (APD) is the influence of the preceding short nightly dwells on the results of a standardized PET. The aim of the study was to compare net ultrafiltration, small solute transport, sodium sieving, and solute transport type between a PET preceded by a long night dwell and one preceded by short (APD) dwells.


METHODS
13 stable APD patients (mean age 60 +/- 15 years; mean duration of peritoneal dialysis 31 +/- 15 months) underwent 2 PETs: 1 preceded by short nightly dwells (PET A) and 1 preceded by a long night dwell (PET B).


RESULTS
Both PETs were performed within a mean period of 8 (range 5 - 11) days. Mean total ultrafiltration of PET A was 626 +/- 218 mL and PET B was 644 +/- 223 mL (NS). The 4-hour results of both tests for dialysate-to-plasma (D/P) ratios of creatinine and urea, D(t)/D(0) ratios of glucose, and the dip in D/P sodium (sodium sieving) were similar. Classification of transport categories was identical for 10 of 13 patients.


CONCLUSIONS
In APD, the preceding dwell time of a 3.86% glucose PET does not influence fluid transport, solute transport, or transport type.
Cnossen
Trijntje
T
Internal Medicine, Maastricht UMC, Maastricht, The Netherlands. nynke.cnossen@mumc.nl
Beerenhout
Charles
C
Smit
Watske
W
Konings
Constantijn
C
Kooman
Jeroen
J
Leunissen
Karel
K
Krediet
Raymond T
RT
D005260:Female; D005947:Glucose / Q000008:administration & dosage* / Q000032:analysis*; D015312:Hemodialysis Solutions / Q000737:chemistry*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D010537:Peritoneum / Q000378:metabolism*; D013997:Time Factors
D015312:Hemodialysis Solutions; D005947:Glucose