Rhegmatogenous retinal detachment following treatment for retinoblastoma.
OBJECTIVE
To elucidate characteristics of rhegmatogenous retinal detachment that developed in children who underwent treatment for retinoblastoma and to analyze the outcome following vitreoretinal surgery in such clinical settings.


METHODS
This was a retrospective case series of 9 eyes of 9 patients who underwent vitreoretinal surgery for tumor control and retinal reattachment.


RESULTS
At the time of diagnosis of rhegmatogenous retinal detachment, retinoblastoma was regressed in 6 eyes (67%). The retinal detachment involved less than two quadrants in 7 eyes (78%) and was caused by an atrophic break in 7 eyes. Seven eyes underwent a non-drainage scleral buckling procedure. Three eyes underwent vitreous surgery; in 2 of these eyes, tumor excision along with retinectomy using melphalan infusion was performed and eventually silicone oil tamponade was used. Retinal reattachment was achieved in all eyes with eventual tumor control in 7 eyes. The median follow-up after retinal reattachment surgery was 24 months.


CONCLUSIONS
Rhegmatogenous retinal detachment in treated eyes with retinoblastoma is usually caused by an atrophic retinal break. Retinal detachment can be repaired successfully in most eyes.
Saumya Pal
Swakshyar
S
Vision Research Foundation, Chennai, Tamil Nadu, India.
Gopal
Lingam
L
Khetan
Vikas
V
Nagpal
Amit
A
Sharma
Tarun
T
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D017679:Cryotherapy; D058450:Endotamponade; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D007223:Infant; D017075:Laser Coagulation; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011882:Radiotherapy, High-Energy; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D019572:Retinal Neoplasms / Q000473:pathology / Q000628:therapy*; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D012175:Retinoblastoma / Q000473:pathology / Q000628:therapy*; D012591:Scleral Buckling; D013997:Time Factors; D016896:Treatment Outcome; D014821:Vitrectomy; D057586:Vitreoretinal Surgery
D000970:Antineoplastic Agents; D008558:Melphalan