Bilateral internal carotid artery occlusions in a pediatric patient with refractory acute myeloid leukemia.
Thromboembolism is a well-known complication of cancer including acute myeloid leukemia (AML) especially in patients with high myeloblast counts. However, spontaneous vaso-occlusion in the main arteries is very rare especially in patients with low blast counts and no pre existing vasculopathy. We report the case of a 3-year-old male with refractory AML who developed spontaneous bilateral internal carotid artery occlusion with diffuse cerebral infarcts. Strokes are rarely secondary to spontaneous carotid artery thrombosis and few cases have been reported in the literature.
Fuh
Beng
B
East Carolina University Brody School of Medicine, Greenville, NC, USA. fuhb@ecu.edu
Lurito
Joseph
J
Grossi
Mauro
M
Daeschner
Charles
C
Russo
Suzanne
S
D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000209:etiology* / Q000473:pathology; D002544:Cerebral Infarction / Q000209:etiology* / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male