Malignant transformation in mature cystic teratoma of the ovary: three cases mimicking primary ovarian epithelial tumors.
This study reports 3 unusual cases of malignant transformation in mature cystic teratoma of the ovary (dermoid cyst), namely carcinosarcoma, atypical choroid plexus papilloma, and papillary thyroid carcinoma, the last case involving both ovaries and with peritoneal dissemination. Adequate sampling is essential in such ovarian tumors to establish their teratomatous origin and avoid an erroneous diagnosis of primary ovarian or metastatic tumors. The authors present the clinicopathological findings in these 3 cases with a review of literature.
Quadri
Asif M
AM
Department of Histopathology, Birmingham Women's Hospital Foundation Trust, Edgbaston, Birmingham, UK.
Ganesan
Raji
R
Hock
Ye Lin
YL
Karim
Sabeeha Naheed
SN
Hirschowitz
Lynn
L
D000328:Adult; D002277:Carcinoma; D002291:Carcinoma, Papillary; D002296:Carcinosarcoma / Q000175:diagnosis* / Q000628:therapy; D002471:Cell Transformation, Neoplastic; D003131:Combined Modality Therapy; D003884:Dermoid Cyst / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000628:therapy; D010052:Ovariectomy; D020288:Papilloma, Choroid Plexus / Q000175:diagnosis* / Q000628:therapy; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000628:therapy; D013965:Thyroidectomy; D016896:Treatment Outcome