Major depressive disorder preceding the onset of progressive supranuclear palsy.
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by vertical supranuclear palsy and parkinsonian symptoms. The neuropsychiatric symptoms of PSP include anhedonia, depressed mood and cognitive impairment. Patients with PSP have an increased risk for developing depressive disorders within the next year. However, it is rare to find that major depressive disorder was the antecedent diagnosis of a patient who was later diagnosed with PSP. We present here a patient who suffered from PSP with repetitive falls, a masked face and dysarthria after developing a major depressive disorder.
Kim
Won-Hyoung
WH
Department of Psychiatry, College of Medicine, Inha University, Incheon, Korea.
Lee
Young-Soo
YS
Jung
Seung-Ho
SH
Choi
Hye-Jin
HJ
Lee
Myung-Ji
MJ
Kang
Min-Hee
MH
Kim
Chul-Eung
CE
Lee
Jeong-Seop
JS
Bae
Jae-Nam
JN