Glycosphingolipids as mediators of phenotypic changes associated with development and cancer progression.
Sen-itiroh Hakomori has been involved for the past approximately 40 years in studies on structure and function of glycosphingolipids (GSLs). The following is a brief summary of highlights of his research, performed in association with his colleagues.
Igarashi
Yasuyuki
Y
Dept. of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. yigarash@pharm.hokudai.ac.jp
Kannagi
Reiji
R
D000818:Animals; D018450:Disease Progression; D006028:Glycosphingolipids / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D010641:Phenotype
D006028:Glycosphingolipids