title: [A case of liver metastasis of rectal cancer demonstrating complete response for more than two years to mFOLFOX6].
abstract: A man in his fifties with rectal cancer underwent low anterior resection in another Hospital in January 2006. He was finally diagnosed with Stage III a (pA, pN1, H0, P0). The patient who had postoperative complication such as ruptured suture left the hospital in May 2006, when he was detected with multiple liver metastases and was referred to our hospital for systemic chemotherapy. Systemic chemotherapy with mFOLFOX6 was performed from May 2006. Grade 3 diarrhea and grade 2 peripheral neuropathy, nausea and vomiting were observed. After 6 courses of mFOLFOX6, MRI revealed metastasis had been disappeared and levels of CEA and CA19-9 were decreased below normal. The treatment has been discontinued. Recurrence was not observed for 30 months.
authors.affiliation: Department of Surgery, Minoh City Hospital.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Miyo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kato
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Aya
authors.initials: A
authors.lastname: Kato
authors.forename: Takuya
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Doi
authors.forename: Minako
authors.initials: M
authors.lastname: Hoshi
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Makari
authors.forename: Satoshi
authors.initials: S
authors.lastname: Oshima
authors.forename: Shouhei
authors.initials: S
authors.lastname: Iijima
authors.forename: Eiji
authors.initials: E
authors.lastname: Kurokawa
authors.forename: Nobuteru
authors.initials: N
authors.lastname: Kikkawa
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil