title: Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells.
abstract: Four new lanostane triterpenes, butyl ganoderate A (1), butyl ganoderate B (2), butyl lucidenate N (3), and butyl lucidenate A (4), were isolated from the fruiting bodies of Ganoderma lucidum together with 14 known compounds (5-18). The structures of the new triterpenes were established by extensive spectroscopic studies and chemical evidence. In addition, the inhibitory effect of isolated compounds on adipocyte differentiation in 3T3-L1 cells was examined.
authors.affiliation: College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea.
authors.forename: IkSoo
authors.initials: I
authors.lastname: Lee
authors.forename: JungJu
authors.initials: J
authors.lastname: Seo
authors.forename: JinPyo
authors.initials: J
authors.lastname: Kim
authors.forename: HongJin
authors.initials: H
authors.lastname: Kim
authors.forename: UiJung
authors.initials: U
authors.lastname: Youn
authors.forename: Joonseok
authors.initials: J
authors.lastname: Lee
authors.forename: HyunJu
authors.initials: H
authors.lastname: Jung
authors.forename: MinKyun
authors.initials: M
authors.lastname: Na
authors.forename: Masao
authors.initials: M
authors.lastname: Hattori
authors.forename: ByungSun
authors.initials: B
authors.lastname: Min
authors.forename: KiHwan
authors.initials: K
authors.lastname: Bae
mesh_terms: D041721:3T3-L1 Cells; D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D007564:Japan; D007810:Lanosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D020940:Reishi / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D014315:Triterpenes; D007810:Lanosterol