title: Polycystic ovary syndrome: a biopsychosocial understanding in young women to improve knowledge and treatment options.
abstract: OBJECTIVE
  To assess psychological features in young women with and without PCOS.
  
  
  METHODS
  Observational, cross-sectional pilot study in young women aged 18-25 with (n = 24) or without (n = 22) PCOS (age: 22.41 +/- 0.39 vs. 21.95 +/- 0.47 years, p = 0.46; BMI: 29.17 +/- 1.54 vs. 22.05 +/- 0.83 kg/m(2), p = 0.0003). The main outcome measures were quality of life, anxiety, depression, risk perception and fears on future health.
  
  
  RESULTS
  Women with PCOS demonstrated worsened quality of life (p = 0.033) and greater anxiety (p = 0.01) and depression (p = 0.023) than women without PCOS related to BMI status. Women with PCOS were more likely to perceive themselves as at risk of obesity (p = 0.012) and infertility (p < 0.0001), and perceived greater importance in reducing future risk of prediabetes (p = 0.027), gestational diabetes (p = 0.039), type 2 diabetes (p = 0.01), heart disease (p = 0.005), obesity (p = 0.0007) and infertility (p = 0.023) than women without PCOS. Women with PCOS were more likely to have fears about future health related to weight gain (p = 0.045), loss of femininity (p = 0.035), loss of sexuality (p = 0.003) and infertility (p = 0.019) than women without PCOS.
  
  
  CONCLUSIONS
  Worsened quality of life, anxiety and depression in young women with PCOS is related to BMI. Risk perception is appropriately high in PCOS, yet perceived risks of future metabolic complications are less common than those related to weight gain and infertility.
authors.affiliation: The Jean Hailes Foundation for Women's Health Research Group, Monash University, Clayton, Australia. lisa.moran@med.monash.edu.au
authors.forename: Lisa
authors.initials: L
authors.lastname: Moran
authors.forename: Melanie
authors.initials: M
authors.lastname: Gibson-Helm
authors.forename: Helena
authors.initials: H
authors.lastname: Teede
authors.forename: Amanda
authors.initials: A
authors.lastname: Deeks
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology / Q000523:psychology; D001315:Australia; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology / Q000523:psychology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000523:psychology; D009765:Obesity / Q000453:epidemiology / Q000523:psychology; D010865:Pilot Projects; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology* / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D012307:Risk Factors; D016387:Women's Health; D055815:Young Adult