title: [A case of rectal cancer with lung metastases responding to cetuximab].
abstract: We report a 73-year-old male patient who underwent low anterior resection for rectal cancer (Stage IIIb). Nine months after the surgery, multiple metastases of liver, lung, brain and lymph node were detected. He was treated with FOLFOX4 and FOLFIRI though lung metastases progressed and caused dyspnea. Cetuximab plus irinotecan therapy was dramatically effective, which improved his quality of life for over 10 months.
authors.affiliation: Department of Surgical Oncology, Tokyo Medical and Dental University.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kawai
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Uetake
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Enomoto
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Higuchi
authors.forename: Masamichi
authors.initials: M
authors.lastname: Yasuno
authors.forename: Satoru
authors.initials: S
authors.lastname: Iida
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sugihara
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D000068818:Cetuximab; D006801:Humans; D000077146:Irinotecan; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D000068818:Cetuximab; D002166:Camptothecin