One-pot highly diastereoselective synthesis of cis-vinylaziridines via the sulfur ylide-mediated aziridination and palladium(0)-catalyzed isomerization.
Highly diastereoselective synthesis of cis-trisubstituted vinylaziridines containing a quaternary carbon center is realized by a one-pot protocol in which the combination of sulfur ylide-mediated aziridination of cyclic ketimines and Pd(0)-catalyzed isomerization is employed successfully.
Zhu
Ben-Hu
BH
School of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215123, China.
Zheng
Jun-Cheng
JC
Yu
Chang-Bin
CB
Sun
Xiu-Li
XL
Zhou
Yong-Gui
YG
Shen
Qi
Q
Tang
Yong
Y
D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013457:Sulfur Compounds / Q000737:chemistry*; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D001388:Aziridines; D013457:Sulfur Compounds; D014753:Vinyl Compounds; D010165:Palladium