title: Strengthening institutional review board review of highly innovative interventions in clinical trials.
authors.affiliation: Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. bernie@medicine.ucsf.edu
authors.forename: Bernard
authors.initials: B
authors.lastname: Lo
authors.forename: Deborah
authors.initials: D
authors.lastname: Grady
mesh_terms: D000046:Academic Medical Centers; D002986:Clinical Trials as Topic / Q000941:ethics*; D030881:Disclosure / Q000941:ethics*; D064420:Drug-Related Side Effects and Adverse Reactions; D028744:Ethics Committees, Research; D006801:Humans; D009316:National Institutes of Health (U.S.); D012306:Risk; D014481:United States