title: Overweight and seminal quality: a study of 794 patients.
abstract: OBJECTIVE
  To evaluate sperm quality, levels of markers of epididymal and accessory gland function, and T in semen from men grouped according to their body mass index (BMI).
  
  
  METHODS
  Blind prospective study.
  
  
  METHODS
  Andrology and reproduction laboratory in Cordoba, Argentina (2006-2007).
  
  
  METHODS
  Seven hundred ninety-four men.
  
  
  METHODS
  None.
  
  
  METHODS
  In semen samples, sperm quality (volume, density, motility, morphology, viability, hypoosmotic swell test, and nuclear maturity) and levels of neutral alpha-glucosidase, fructose, citric acid and T.
  
  
  RESULTS
  Multivariate analysis showed a negative association between BMI and motility, rapid motility and neutral alpha-glucosidase levels, and a positive association between BMI and seminal fructose levels. No associations were found among BMI and sperm concentration, the other parameters evaluated, or seminal T levels.
  
  
  CONCLUSIONS
  Results found in our study support a deleterious effect of obesity on seminal quality, probably by alterations in the function of the epididymis (i.e., in epididymal maturation).
authors.affiliation: Established investigator from the Consejo Nacional de Investigaciones Científicas y Tecnológicas, Instituto de Fisiología, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina. acmartini2000@yahoo.com
authors.forename: Ana C
authors.initials: AC
authors.lastname: Martini
authors.forename: Andrea
authors.initials: A
authors.lastname: Tissera
authors.forename: Daniel
authors.initials: D
authors.lastname: Estofán
authors.forename: Rosa I
authors.initials: RI
authors.lastname: Molina
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Mangeaud
authors.forename: Marta Fiol
authors.initials: MF
authors.lastname: de Cuneo
authors.forename: Rubén D
authors.initials: RD
authors.lastname: Ruiz
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002470:Cell Survival / Q000502:physiology; D004822:Epididymis / Q000502:physiology; D005837:Genitalia, Male / Q000502:physiology; D006801:Humans; D007246:Infertility / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D050177:Overweight / Q000150:complications / Q000503:physiopathology*; D011446:Prospective Studies; D055101:Semen Analysis; D016037:Single-Blind Method; D013076:Sperm Count; D013081:Sperm Motility / Q000502:physiology*; D013094:Spermatozoa / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism
chemical_list: D013739:Testosterone