title: Bilateral endophthalmitis as the initial presentation of bacterial meningitis.
abstract: To report a case of bilateral endophthalmitis as the initial presentation of bacterial meningitis in a young, immunocompetent Korean patient. A 35-year-old female with a one day history of bilateral swollen eyes, visual disturbance, headache, petechial skin rash, and nausea visited our clinic. She was diagnosed as having endogenous endophthalmitis associated with bacterial meningitis. Intravenous broad spectrum antibiotic therapy was initiated with cefotaxime 3 g and ubacillin 3 g, four times daily. Intravitreal antibiotic (vancomycin 1 mg/0.1 mL and ceftazidime 2 mg/0.1 mL) injections were performed in both eyes. Two weeks post presentation, the best corrected visual acuity in both eyes improved to 0.7, and inflammation of the anterior chamber and vitreous cavity was decreased. We recommend that when endogenous endophthalmitis is suspected along with meningitis, or if it is known to be present, intravitreal and intravenous antibiotics should be promptly administered to preserve vision.
authors.affiliation: Department of Ophthalmology, Gyeongsang National University, College of Medicine, #162 Ilsan-dong, Jinju, Korea.
authors.forename: Seong-Jae
authors.initials: SJ
authors.lastname: Kim
authors.forename: Seong Wook
authors.initials: SW
authors.lastname: Seo
authors.forename: Jong-Moon
authors.initials: JM
authors.lastname: Park
authors.forename: In-Young
authors.initials: IY
authors.lastname: Chung
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016920:Meningitis, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009887:Ophthalmoscopy
chemical_list: D000900:Anti-Bacterial Agents