title: Triple dye plus rubbing alcohol versus triple dye alone for umbilical cord care.
abstract: Current practices for umbilical cord care vary across centers, but the evidence regarding these practices and their impact on cord separation, complications, and health care use are limited. The objective of this study was to compare the effect of triple dye alone (brilliant green, crystal violet, and proflavine hemisulfate) versus triple dye plus rubbing alcohol (isopropyl alcohol) twice daily on time to umbilical cord separation, complications, and health care use. For the 90 newborns who completed the study, there were no significant differences between treatment groups for time to cord separation, cord-related morbidities, or cord-related urgent care. Based on these study results, there does not appear to be significant benefit to the addition of twice daily applications of rubbing alcohol to neonatal umbilical cords following triple dye treatment after birth.
authors.affiliation: Pediatrics HS83, Penn State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA. asuliman@hmc.psu.edu
authors.forename: Alawia K
authors.initials: AK
authors.lastname: Suliman
authors.forename: Heidi
authors.initials: H
authors.lastname: Watts
authors.forename: Jessica
authors.initials: J
authors.lastname: Beiler
authors.forename: Tonya S
authors.initials: TS
authors.lastname: King
authors.forename: Sana
authors.initials: S
authors.lastname: Khan
authors.forename: Marybeth
authors.initials: M
authors.lastname: Carnuccio
authors.forename: Ian M
authors.initials: IM
authors.lastname: Paul
mesh_terms: D019840:2-Propanol / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D016009:Chi-Square Distribution; D004338:Drug Combinations; D005260:Female; D005840:Gentian Violet / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011370:Proflavine / Q000627:therapeutic use*; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*; D016896:Treatment Outcome; D014470:Umbilical Cord / Q000382:microbiology*
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D000644:Quaternary Ammonium Compounds; C014234:Triple Dye; D011370:Proflavine; D005840:Gentian Violet; D019840:2-Propanol