title: [Palatal necrosis due to cocaine abuse].
abstract: The easier access to cocaine allows chronic and intensive consumption. Nasally inhaled cocaine causes important midfacial lesions called: Cocaine Induced Midline Destructive Lesions. These lesions are due to several factors, the anesthetic, vasoconstrictive, locally prothrombotic properties of cocaine and its components combined with cytotoxic effects and traumatic nasal injuries related to consumption mode. Functional signs are: nasal regurgitation, rhinolalia, rhinorrhea, and midfacial pain. The morphological modifications of the nasal pyramid feature the destruction of bone and cartilage structures. Endo-buccal examination, anterior rhinoscopy, and TDM reveal palatine necrosis of variable extension. Nasal fossae superinfection is always present. Sinus superinfection is frequent. Management is multidisciplinary. Weaning must be achieved before surgery. It is necessary to rehabilitate speech and swallowing functions by the means of various local or free flaps.
authors.affiliation: Service de chirurgie maxillofaciale, hôpital Roger-Salengro, rue Emile-Laine, 59037 Lille cedex, France. lucmyon@yahoo.fr <lucmyon@yahoo.fr>
authors.forename: L
authors.initials: L
authors.lastname: Myon
authors.forename: A
authors.initials: A
authors.lastname: Delforge
authors.forename: G
authors.initials: G
authors.lastname: Raoul
authors.forename: J
authors.initials: J
authors.lastname: Ferri
mesh_terms: D019970:Cocaine-Related Disorders / Q000150:complications*; D003937:Diagnosis, Differential; D004724:Endoscopy; D005157:Facial Pain / Q000209:etiology; D006801:Humans; D009296:Nasal Cavity / Q000473:pathology; D009336:Necrosis; D009668:Nose Diseases / Q000209:etiology; D016155:Oral Fistula / Q000209:etiology; D010159:Palate / Q000187:drug effects / Q000473:pathology*; D016156:Respiratory Tract Fistula / Q000209:etiology; D012220:Rhinitis / Q000209:etiology; D015163:Superinfection / Q000209:etiology; D014057:Tomography, X-Ray Computed