title: Human uptake of persistent chemicals from contaminated soil: PCDD/Fs and PCBs.
abstract: Trace amounts of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are ubiquitous in the environment. Because of industrial activity, other human activities, and accidents, higher concentrations of these chemicals may be present in soil, in residential and recreational areas. Human uptake of these chemicals from such soils has been assumed by regulators, and people contacting such soils may be concerned about potential adverse health effects. Accordingly, clean up levels have been set by state and federal agencies. Whether and to what extent humans actually take up these chemicals from soil is the focus of this review. Since humans are also exposed to PCDD/Fs and PCBs in food and air, their concentrations in these media are presented. We find that their presence in soils is unlikely to increase human body burdens.
authors.affiliation: Center for Health Risk Evaluation P.O. Box 15452 Washington, DC 20003, USA. renate.kimbrough@verizon.net
authors.forename: Renate D
authors.initials: RD
authors.lastname: Kimbrough
authors.forename: Constantine A
authors.initials: CA
authors.lastname: Krouskas
authors.forename: M Leigh
authors.initials: ML
authors.lastname: Carson
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Long
authors.forename: Christopher
authors.initials: C
authors.lastname: Bevan
authors.forename: Robert G
authors.initials: RG
authors.lastname: Tardiff
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000032:analysis* / Q000493:pharmacokinetics; D001682:Biological Availability; D000072338:Dibenzofurans, Polychlorinated; D004781:Environmental Exposure / Q000032:analysis*; D006801:Humans; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000493:pharmacokinetics; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis / Q000493:pharmacokinetics; D012989:Soil Pollutants / Q000032:analysis* / Q000493:pharmacokinetics
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants; D011078:Polychlorinated Biphenyls