title: [Imported cases of histoplasmosis].
abstract: Histoplasmosis is a fungal infection that may be opportunistic in the context of HIV. Rare in Europe, it is always imported. The two variants of histoplasmosis are encountered in defined geographic areas: var. capsulatum in Americas, Africa and Asia; and var duboisii in Africa only. In immuno-competent patients, acute infection is often asymptomatic, or it may cause a pulmonary syndrome of variable severity. Among immuno-compromised patients, histoplasmosis is disseminated and life-threatening. Diagnosis is typically made by cultures. The treatment of the disseminated form must be started immediately with anti-fungal therapy and highly active anti-retroviral treatment. In a globalized world, one has to remember the importation of unusual exotic diseases.
authors.affiliation: Service des maladies infectieuses, HUG, Genève 14. laurent.nyffenegger@hcuge.ch
authors.forename: Laurent
authors.initials: L
authors.lastname: Nyffenegger
authors.forename: Mohamed
authors.initials: M
authors.lastname: Abbas
authors.forename: Grégoire
authors.initials: G
authors.lastname: Gex
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Boffi
authors.forename: Jacques
authors.initials: J
authors.lastname: Schrenzel
authors.forename: Kalthum
authors.initials: K
authors.lastname: Bouchuiguir-Wafa
authors.forename: Bernard
authors.initials: B
authors.lastname: Hirschel
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D054242:Emigrants and Immigrants; D005260:Female; D015658:HIV Infections / Q000150:complications; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013557:Switzerland