Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.
Smalheiser
Neil R
NR
Department of Psychiatry, UIC Psychiatric Institute MC912, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL 60612, USA.