Pancreatoblastoma: two case reports from a medical center in Taiwan.
Although pancreatoblastoma (PB) is an extremely rare tumor, it is the most common pancreatic tumor in children. We reported 2 cases of PB treated at a medical center in Taiwan. One was a 3.5-year-old boy who presented with abdominal pain. Physical examination demonstrated abdominal masses. Multiple pancreatic and hepatic masses were noted by magnetic resonance imaging. He underwent surgical resection but tumor could not be removed completely, which was confirmed by the pathology. He received chemotherapy consisting of cisplatin and doxorubicin after the surgery but the tumor progressed rapidly. He died of progressive disease and sepsis. The other case was a 4-year-old boy presented with abdominal pain. Computed tomography showed pancreatic tumor. He underwent surgical resection and pathology showed PB. He received chemotherapy after complete tumor resection. He is disease free till now. Complete tumor resection is the major difference of these 2 patients and is the most important factor affecting the outcome.
Huang
Yi-Ling
YL
Departments of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Yang
Yung-Li
YL
Hsu
Wen-Ming
WM
Lai
Hong-Shiee
HS
Lin
Kai-Hsin
KH
Jou
Shiann-Tarng
ST
Lu
Meng-Yao
MY
Chang
Hsiu-Hao
HH
Lin
Dong-Tsamn
DT
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013624:Taiwan; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D004317:Doxorubicin; D002945:Cisplatin