title: Magnetoencephalography discriminates modality-specific infraslow signals less than 0.1 Hz.
abstract: DC-magnetoencephalography (DC-MEG) technique has been refined and allows to record cortical activity in the infraslow frequency range less than 0.1 Hz noninvasively. Important questions however, remained, especially, how specific these infraslow activations can be recorded and whether different activations, for example, motor versus acoustic, can be separated. To clarify these questions, in the present DC-MEG study, cortical infraslow activity was investigated intraindividually in response to different activation modalities, that is, motor versus acoustic: in 13 individuals, 30-s periods of finger movement or listening to concert music, were interleaved for 60 min. DC-MEG was capable to resolve intermodal differences concerning the relative amplitudes, field patterns, and source localizations. These results clarify that DC-MEG allows to identify and to discriminate modality-specific infraslow cortical neuronal signals.
authors.affiliation: Department of Neurology, Charite-Universitaetsmedizin Berlin, Berlin D-12200, Germany. stefanie.leistner@charite.de
authors.forename: Stefanie
authors.initials: S
authors.lastname: Leistner
authors.forename: Tilmann H
authors.initials: TH
authors.lastname: Sander
authors.forename: Gerd
authors.initials: G
authors.lastname: Wuebbeler
authors.forename: Alfred
authors.initials: A
authors.lastname: Link
authors.forename: Clemens
authors.initials: C
authors.lastname: Elster
authors.forename: Gabriel
authors.initials: G
authors.lastname: Curio
authors.forename: Lutz
authors.initials: L
authors.lastname: Trahms
authors.forename: Bruno-Marcel
authors.initials: BM
authors.lastname: Mackert
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D009043:Motor Activity / Q000502:physiology; D055815:Young Adult