title: Systemic allergic contact dermatitis due to consumption of raw shiitake mushroom.
abstract: Shiitake (Lentinus edodes) is a mushroom that is very popular in Asian cuisine. After ingestion of the raw fungus, dermatitis may occur in rare cases, and is commonly assumed to be a toxic reaction. We report a 52-year-old man who developed a generalized pruritic papulovesicular eruption 2 weeks after daily consumption of uncooked shiitake mushrooms. Prick-to-prick and scratch tests with uncooked mushrooms resulted in an eczematous reaction at 24 h that peaked at 72 h and persisted for 1 week. In contrast, no cutaneous reactions could be elicited in 20 healthy people. We conclude that our patient had systemic allergic contact dermatitis due to consumption of raw shiitake mushroom.
authors.affiliation: Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases, Medical University of Vienna, Vienna, Austria. tamara.kopp@meduniwien.ac.at
authors.forename: T
authors.initials: T
authors.lastname: Kopp
authors.forename: P
authors.initials: P
authors.lastname: Mastan
authors.forename: N
authors.initials: N
authors.lastname: Mothes
authors.forename: S
authors.initials: S
authors.lastname: Tzaneva
authors.forename: G
authors.initials: G
authors.lastname: Stingl
authors.forename: A
authors.initials: A
authors.lastname: Tanew
mesh_terms: D017449:Dermatitis, Allergic Contact / Q000188:drug therapy / Q000473:pathology*; D009783:Dermatitis, Occupational / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D010328:Patch Tests; D020942:Shiitake Mushrooms
chemical_list: D008775:Methylprednisolone