[Granulocytic sarcoma in the mandibular gingiva of an HIV+ patient].
BACKGROUND
The association between malignant tumors and HIV infection is well known. We report a rare case of gingival granulocytic sarcoma (GS) associated to HIV infection.


METHODS
A 31 year-old HIV patient consulted for left maxillary tumefaction. His viral load was high (40,112 copies/ml) and CD4 count low (287cells/mm(3)). After biopsy-exeresis, histology and an immunohistochemical study confirmed the diagnosis of GS. Chemotherapy similar to that of acute myeloid leukemia (AML) completed the treatment. The remission was complete at 5 years.


CONCLUSIONS
Only one case of intra-oral GS associated to HIV infection has been reported so far. The clinical and radiological presentation is unspecific. Histology proves the diagnosis. The treatment is comparable to that of AML. The prognosis is usually bad.
Chafai
R
R
Service de médecine carcinologique, CHU Farhat Hached, rue Ibn El Jazzar, 4000 Sousse, Tunisie.
Gharbi
O
O
Trabelsi
A
A
Chabchoub
I
I
Lettaif
O
O
Ben Ahmed
S
S
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D018791:CD4 Lymphocyte Count; D005500:Follow-Up Studies; D005887:Gingival Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D006678:HIV / Q000302:isolation & purification; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D012074:Remission Induction; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000188:drug therapy; D019562:Viral Load