Subacute cutaneous lupus erythematosus presenting as poikiloderma.
Subacute cutaneous lupus erythematosus (SCLE) is a recognised variant of lupus erythematosus (LE), which accounts for 10-15% of all cases of cutaneous LE, occurring most commonly in young to middle-aged white women. Diagnosis is based on the detection of anti-Ro/SS-A antibodies in the skin and serum, characteristic clinical and histological cutaneous involvement, and relatively mild systemic involvement. Several unusual variants of SCLE have been reported including erythrodermic SCLE, SCLE with vitiligo-like lesions, acral SCLE and bullous SCLE. Poikoilodermatous SCLE is a recognised but rare variant of SCLE. There are currently only two case reports, comprising five individual cases, in the literature. We present a case of SCLE in which the main clinical findings were an extensive photodistributed poikilodermatous rash and alopecia.
Hughes
R
R
Department of Dermatology, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland.
Loftus
B
B
Kirby
B
B
D000505:Alopecia / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D011038:Rothmund-Thomson Syndrome / Q000276:immunology / Q000473:pathology*