title: [Prognostic value of laboratory factors of performance status in lung cancer patients].
abstract: Clinical observations indicate that the utility of classical prognostic factors in the assessment of probability of disease free or overall survival of lung cancer patients is not completely satisfactory. This is the cause for search of indices which results would contribute to optimization of this estimation. Of potential value in this aspect may also be the results of laboratory determinations which characterize patient's performance status. Dependencies between the times of overall survival in respect to chosen hematological and biochemical factors from the pretreatment period were analyzed in a group of 233 patients with lung cancer (adenocarcinoma - 44, squamous cell lung cancer - 156, small cell lung cancer - 33 patients) in different stages of disease. Apart from stage of disease and histological type of tumor, independent prognostic factors turned out to be the actual ideal body mass ratio and the number of leucocytes. In patients with less advanced stages of disease, such independent factors, apart from histological type are alpha-1 globulin and gamma globulin.
authors.affiliation: Zakład Analityki i Biochemii Klinicznej, Centrum Onkologii, Oddział w Krakowie, Instytut im. M. Skłodowskiej-Curie, Kraków.
authors.forename: Ewa
authors.initials: E
authors.lastname: Wójcik
authors.forename: Urszula
authors.initials: U
authors.lastname: Rychlik
authors.forename: Zofia
authors.initials: Z
authors.lastname: Stasik
authors.forename: Jan
authors.initials: J
authors.lastname: Kulpa
authors.forename: Marian
authors.initials: M
authors.lastname: Reinfuss
authors.forename: Piotr
authors.initials: P
authors.lastname: Skotnicki
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D055752:Small Cell Lung Carcinoma / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D015996:Survival Rate
chemical_list: D014408:Biomarkers, Tumor