title: Takayasu's Arteritis Involving the Ostia of Three Large Coronary Arteries.
abstract: Takayasu's arteritis can involve the ostia of coronary arteries. We report a patient with Takayasu's arteritis involving the ostia of three large coronary arteries who was successfully treated by percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) and had a good clinical outcome after 12 months. A 37-year-old male with unstable angina was admitted to our cardiovascular center. The patient had Takayasu's arteritis and an aortic valve replacement with a metallic valve due to severe aortic regurgitation 7 years previously. Coronary angiography (CAG) showed a 95% discrete eccentric luminal narrowing at the ostia of the large left anterior descending (LAD) and left circumflex (LCX) arteries, and a 99% discrete eccentric luminal narrowing at the ostium of the large right coronary artery (RCA). The patient was treated with prednisolone for 14 days. Two large paclitaxel-eluting stents (PES) were then implanted in the distal left main coronary artery using the kissing stent technique. After 6 months, a CAG did not reveal restenosis or recurrent coronary artery disease. Thus, PCI with a DES for patients with significant coronary involvement secondary to Takayasu's arteritis is an effective and an alternative treatment when coronary bypass grafting is not option.
authors.affiliation: Department of Internal Medicine/Cardiac Catheterization Laboratory, Pusan National University Hospital, Busan, Korea.
authors.forename: Jin-Sup
authors.initials: JS
authors.lastname: Park
authors.forename: Han Cheol
authors.initials: HC
authors.lastname: Lee
authors.forename: Sang-Kwon
authors.initials: SK
authors.lastname: Lee
authors.forename: Sang-Pil
authors.initials: SP
authors.lastname: Kim
authors.forename: Yeong Dae
authors.initials: YD
authors.lastname: Kim
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Ahn
authors.forename: Taek Jong
authors.initials: TJ
authors.lastname: Hong