title: Short-term infection in cuffed versus noncuffed small bore central catheters: a randomized trial.
abstract: OBJECTIVE
  To determine if a polyester cuff offered benefit in jugular small-bore central catheters (SBCCs).
  
  
  METHODS
  Eighty-four patients were randomly assigned to receive a 5-F single- or 6-F dual-lumen SBCC with (n = 42) or without (n = 42) a polyester cuff. Follow-up was performed at 2 weeks, 1 month, and 3 months or at catheter removal, whichever came first. At scheduled follow-up, catheter function, patient satisfaction, and infection were determined. At catheter removal, tip culture was performed to determine colonization and jugular vein patency was determined with ultrasonography (US).
  
  
  RESULTS
  The overall infection rate was 0.4 per 1,000 catheter days. There was one clinical infection (noncuffed catheter). Colonization occurred in two noncuffed catheters and one cuffed catheter. There was one catheter dislodgment in the noncuffed group and none in the cuffed group. Cuffed catheters were no more difficult to insert but took slightly longer to remove (6 minutes +/- 4.7 vs 5 minutes +/- 3, P = .39) and often required local anesthesia for removal, whereas noncuffed catheters did not (41% vs 0%, P = .001). Partial (two cuffed, 0 noncuffed) or complete (two cuffed, one noncuffed) jugular thrombosis was seen on five of 58 completion US studies (8.6%).
  
  
  CONCLUSIONS
  A polyester cuff on a SBCC confers no significant benefit in short-term colonization rates. Infection in SBCCs is uncommon. Despite their small diameters, SBCCs can result in jugular thrombosis, an important consideration in any patient requiring long-term venous access.
authors.affiliation: Department of Radiology, Division of Interventional Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce St, Philadelphia, PA 19104, USA. streroto@uphs.upenn.edu
authors.forename: Scott O
authors.initials: SO
authors.lastname: Trerotola
authors.forename: Aalpen A
authors.initials: AA
authors.lastname: Patel
authors.forename: Richard D
authors.initials: RD
authors.lastname: Shlansky-Goldberg
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Solomon
authors.forename: Jeffrey I
authors.initials: JI
authors.lastname: Mondschein
authors.forename: S William
authors.initials: SW
authors.lastname: Stavropoulos
authors.forename: Michael C
authors.initials: MC
authors.lastname: Soulen
authors.forename: Maxim
authors.initials: M
authors.lastname: Itkin
authors.forename: Jesse
authors.initials: J
authors.lastname: Chittams
mesh_terms: D000328:Adult; D000368:Aged; D055499:Catheter-Related Infections / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D002908:Chronic Disease; D004867:Equipment Design; D005260:Female; D006801:Humans; D007601:Jugular Veins / Q000000981:diagnostic imaging / Q000503:physiopathology; D007674:Kidney Diseases / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011091:Polyesters; D011446:Prospective Studies; D006435:Renal Dialysis; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D014654:Vascular Patency; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D055815:Young Adult
chemical_list: D011091:Polyesters