title: [A patient with metachronous ovarian metastases of signet-ring cell carcinoma of the transverse colon showing long-term survival after surgery].
abstract: The patient was a 43-year-old female who consulted a local physician due primarily to lower abdominal pain. She was referred to our hospital for close evaluation and treatment. Since circumferential cancer was detected in the transverse colon by lower digestive tract endoscopy, the patient was hospitalized for surgical treatment. Transverse colectomy (Cur A) was performed, histopathological examination indicated signet-ring cell carcinoma of the transverse colon, and the lesion was diagnosed as type 4, SS, ly3, v0, n1 (+), Stage III a. Postoperative adjuvant chemotherapy was recommended, but the patient was psychologically unstable and strongly rejected chemotherapy. The patient was periodically followed-up after surgery, but a mass was detected in the left ovary by CT after 1 year and 6 months, and bilateral ovariectomy was performed with a diagnosis of ovarian metastasis. The histopathological diagnosis was signet-ring cell carcinoma, and the ovarian lesions were judged to be metastases of the transverse colon carcinoma. Since the patient did not consent to postoperative chemotherapy, as after the initial surgery, she was followed-up without treatment. She was admitted with ileus due to peritoneal metastasis 4 years and 10 months after the initial surgery, and, despite of the surgery, she died due to carcinoma 5 years after the initial surgery.
authors.affiliation: Department of Surgery, Nishijin Hospital.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Takagi
authors.forename: Yuen
authors.initials: Y
authors.lastname: Nakase
authors.forename: Kanehisa
authors.initials: K
authors.lastname: Fukumoto
authors.forename: Takuya
authors.initials: T
authors.lastname: Miyagaki
authors.forename: Noritaka
authors.initials: N
authors.lastname: Yamakawa
authors.forename: Keiko
authors.initials: K
authors.lastname: Taniike
authors.forename: Yuka
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kanemitsu
authors.forename: Kyouichi
authors.initials: K
authors.lastname: Kassai
authors.forename: Kyouko
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Shinya
authors.initials: S
authors.lastname: Takenaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Itani
mesh_terms: D000328:Adult; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D044684:Colon, Transverse; D003110:Colonic Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000556:secondary* / Q000601:surgery*; D010052:Ovariectomy