[Diagnosis of a human rabies case in Jujuy, 2008].
On July 22, 2008, a previously healthy 8 years old boy from Jujuy, Argentina, died of encephalitis later confirmed as rabies. Diagnosis was made on the basis rabies-specific antibodies presence in a serum sample and it was confirmed by detection of the viral antigens in brain necropsy using the immunofluorescent test. Antigenic characterization identified dog as source of infection. Molecular analysis recognized the same genetic variant circulating in Jujuy since 2003. This report presents the patient's clinical course and the epidemiologic investigation that revealed a dog bite 60 days before the illness onset and the lack of rabies treatment.
Gury-Dohmen
Federico
F
Instituto de Zoonosis Dr. Luis Pasteur, Jujuy, Argentina.
Baspineiro
Berta
B
Gury
Graciela
G
Martínez
Leila
L
Miranda
María Rosa
MR
Cisterna
Daniel M
DM
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001733:Bites and Stings / Q000150:complications*; D001921:Brain / Q000473:pathology; D002648:Child; D004285:Dogs; D018792:Encephalitis, Viral / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D011818:Rabies / Q000276:immunology / Q000473:pathology*; D011820:Rabies virus / Q000276:immunology / Q000302:isolation & purification
D000956:Antigens, Viral