title: [A case of unresectable type 4 gastric cancer which has kept a long-term partial response with adjuvant systemic chemotherapy].
abstract: A 69-year-old woman was admitted to our hospital with complaint of epigastric discomfort in February 2006. The detailed examination had revealed type 4 advanced gastric cancer. An exploratory laparotomy was performed for the unresectable case due to peritonitis cartinomatoza. Postoperative S-1 monotherapy (100 mg/body, 4 weeks on, 2 weeks off) was started as an outpatient in April 2006. After 3-course, partial response (PR) was observed for the primary lesion by gastrointestinal endoscopy. In April 2007, the regimen was changed to S-1 (100 mg/body, 3 weeks on, 2 weeks off)+CDDP (60 mg/m2, days 8) combined chemotherapy, then the primary lesion showed a slight increase. Thereafter, the regimen was changed to S-1 monotherapy in March 2008, and S-1+CDDP combined therapy in July 2008 again. PR was kept observed for three years successfully after the exploratory laparotomy. A case of type 4 unresectable gastric cancer was reported that the postoperative chemotherapy of S-1 was effective.
authors.affiliation: Department of Surgery, Sasebo Chuo Hospital.
authors.forename: Keiji
authors.initials: K
authors.lastname: Kajihara
authors.forename: Kousei
authors.initials: K
authors.lastname: Izumino
authors.forename: Yu
authors.initials: Y
authors.lastname: Shigemasa
authors.forename: Nobufumi
authors.initials: N
authors.lastname: Sasaki
authors.forename: Hideki
authors.initials: H
authors.lastname: Ikari
authors.forename: Teruhisa
authors.initials: T
authors.lastname: Shimizu
authors.forename: Tadaomi
authors.initials: T
authors.lastname: Kunizaki
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Yonemitsu
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D006801:Humans; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin