title: High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome.
abstract: The patient was a 57-year-old man with Brugada syndrome, who had been implanted with a implantable cardioverter defibrillator (ICD). The frequency of ventricular fibrillation (VF) started to increase about 4 years after ICD implantation, occurring, at worst, six times in one night. Immediately after starting oral administration of disopyramide, VF stopped occurring. He then discontinued taking disopyramide, but immediately after the discontinuation VF started occurring again, so he restarted taking disopyramide. Thereafter, VF completely stopped occurring. Findings observed in our case suggest that disopyramide could be added in our arsenal of medications for treating arrhythmic storms in patient with Brugada syndrome.
authors.affiliation: Department of Cardiology, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
authors.forename: Shunichiro
authors.initials: S
authors.lastname: Sumi
authors.forename: Seiyo
authors.initials: S
authors.lastname: Maruyama
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Shiga
authors.forename: Sunao
authors.initials: S
authors.lastname: Kodama
authors.forename: Kei
authors.initials: K
authors.lastname: Miyoshi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Tojou
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yamanouchi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Urata
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D053840:Brugada Syndrome / Q000188:drug therapy* / Q000628:therapy; D017147:Defibrillators, Implantable; D004206:Disopyramide / Q000627:therapeutic use*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000627:therapeutic use; D014693:Ventricular Fibrillation / Q000188:drug therapy* / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D004206:Disopyramide; D011802:Quinidine