title: Postprandial triglyceride response in men: role of overweight, abdominal fat and nutrition.
abstract: OBJECTIVE
  The study analyses i) the effect of overweight, waist circumference and dietary habits on postprandial (pp) triglyceride (TG) response and compares ii) pp TG response with fasting TG levels and iii) pp TG peak values with TG-AUC (area under curve) with respect to cardiometabolic risk assessment.
  
  
  METHODS
  In 100 men (44-68 years) body composition (air-displacement plethysmography), dietary habits, cardiometabolic risk and pp lipid metabolism (standardised lipid load) were assessed. A pp TG peak value of 260 mg/dl was used as a cut-off to classify TG normal- and high-responders.
  
  
  RESULTS
  pp TG response had positive associations with BMI (r = 0.24; p < 0.05), fat mass (r = 0.28; p < 0.01), waist circumference (r = 0.33; p < 0.01), systolic blood pressure (r = 0.21; p < 0.05), fasting (r = 0.29; p < 0.01) and pp glucose (r = 0.40; p < 0.001), fasting (r = 0.38; p < 0.001) and pp insulin levels (r = 0.46; p < 0.001), and inverse associations with HDL-C (r = -0.43; p < 0.001) and intake of dietary fibre (r = -0.31; p < 0.05). Fasting TG levels had a greater contribution to the variance in 12 of 14 cardiometabolic risk factors compared to pp TG response. TG-AUC was highly correlated to cardiometabolic risk.
  
  
  CONCLUSIONS
  Overweight, abdominal fat and a low intake of dietary fibre were determinants of increased pp TG response. Contrary to findings in younger normal-weight men, fasting TG levels had a stronger association with cardio metabolic risk compared to pp TG response. This might be explained by differences in fat mass.
authors.affiliation: Institute of Human Nutrition and Food Science, Christian-Albrechts-University Kiel, Kiel, Germany.
authors.forename: Britta
authors.initials: B
authors.lastname: Hitze
authors.forename: Diana
authors.initials: D
authors.lastname: Rubin
authors.forename: Ulf
authors.initials: U
authors.lastname: Helwig
authors.forename: Jürgen
authors.initials: J
authors.lastname: Schrezenmeir
authors.forename: Anja
authors.initials: A
authors.lastname: Bosy-Westphal
authors.forename: Manfred J
authors.initials: MJ
authors.lastname: Müller
mesh_terms: D050153:Abdominal Fat / Q000378:metabolism*; D000328:Adult; D000368:Aged; D019540:Area Under Curve; D001823:Body Composition / Q000502:physiology; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000378:metabolism; D004043:Dietary Fiber / Q000008:administration & dosage; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D050177:Overweight / Q000453:epidemiology* / Q000378:metabolism*; D019518:Postprandial Period; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference
chemical_list: D004043:Dietary Fiber; D014280:Triglycerides