Life threatening protamine reaction during bypass surgery--a case report.
An anaphylactic reaction to protamine sulphate during cardiac surgery is a rare but known entity. Preoperative prediction and outcome of such a reaction is still unclear. We report a case of severe anaphylactic reaction to protamine sulphate in a diabetic while performing beating heart bypass surgery. We also reviewed the literature and discussed the management of such cases.
Mishra
Dillip Kumar
DK
Department of Cardiovascular Surgery, Apollo Hospitals, Chennai - 600 006, India. drdkm2002@yahoo.com
Sathyamurthy
I
I
Subramanyan
K
K
Girinath
M R
MR
D000707:Anaphylaxis / Q000139:chemically induced* / Q000628:therapy; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects*; D017809:Fatal Outcome; D006494:Heparin Antagonists / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011479:Protamines / Q000009:adverse effects*; D012307:Risk Factors
D006494:Heparin Antagonists; D011479:Protamines