title: [A successful case of advanced breast cancer of the elderly treated with the only breast-hormone therapy as PST].
abstract: An 83-year-old postmenopausal woman was referred to our hospital in order to get the treatment for ER positive advanced breast cancer (T4aN2M0, stage III b). The patient was diagnosed as the dissected aortic aneurysm and the hypertension. It was decided that an operation and chemotherapy would be too difficult with high existing risks. As a result, she was treated with anastrozole of PST, a 3rd-generation aromatase inhibitor, which led to the marked regression of the left breast cancer within a month. The cancer wasn't visualized after eighteen months. With the ongoing breast-hormone Therapy, no remote metastasis has been found after thirty months to this day. The patient hasn't experienced any adverse effects with the above-mentioned therapy. We concluded that the hormone (anastrozole) therapy as PST is a useful treatment for elderly postmenopausal woman with ER positive advanced breast cancer.
authors.affiliation: Department of Surgery, Kitasato University.
authors.forename: Keiko
authors.initials: K
authors.lastname: Hayashi
authors.forename: Norihiko
authors.initials: N
authors.lastname: Sengoku
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Kosaka
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kondou
authors.forename: Naoko
authors.initials: N
authors.lastname: Sugiyama
authors.forename: Takumo
authors.initials: T
authors.lastname: Enomoto
authors.forename: Masaru
authors.initials: M
authors.lastname: Kuranami
authors.forename: Masahiko
authors.initials: M
authors.lastname: Watanabe
mesh_terms: D000369:Aged, 80 and over; D000077384:Anastrozole; D000784:Aortic Dissection / Q000150:complications; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D017545:Aortic Aneurysm, Thoracic / Q000150:complications; D001943:Breast Neoplasms / Q000188:drug therapy*; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D009570:Nitriles / Q000627:therapeutic use*; D011960:Receptors, Estrogen / Q000032:analysis; D014230:Triazoles / Q000627:therapeutic use*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D011960:Receptors, Estrogen; D014230:Triazoles; D000077384:Anastrozole