title: Novel influenza A(H1N1) in a pediatric health care facility in New York City during the first wave of the 2009 pandemic.
abstract: OBJECTIVE
  To describe the burden of care experienced by our pediatric health care facility in New York, New York, from May 3, 2009, to July 31, 2009, during the novel influenza A(H1N1) pandemic that began in spring 2009.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Pediatric emergency departments and inpatient facilities of New York-Presbyterian Hospital. Patients Children presenting to the emergency departments with influenza-like illness (ILI) and children aged 18 years or younger hospitalized with positive laboratory test results for influenza A from May 3, 2009, to July 31, 2009.
  
  
  METHODS
  Proportion of children with ILI who were hospitalized and proportion of hospitalized children with influenza A with respiratory failure, bacterial superinfection, and mortality.
  
  
  RESULTS
  When compared with the same period in 2008, the pediatric emergency departments experienced an excess of 3750 visits (19.9% increase). Overall, 27.7% of visits were for ILI; 2.5% of patients with ILI were hospitalized. Of the 115 hospitalized subjects with confirmed influenza A (median age, 4.3 years), 93 (80.9%) had underlying conditions. Four (3.5%) had identified bacterial superinfection, 1 (0.9%) died, and 35 (30.4%) were admitted to a pediatric intensive care unit; of these 35 patients, 11 had pneumonia and required mechanical ventilation, including high-frequency oscillatory ventilation (n = 3).
  
  
  CONCLUSIONS
  At our center, 2.5% of children with ILI presenting to the emergency departments during the first wave of the 2009 novel influenza A(H1N1) pandemic were hospitalized. Of the 115 hospitalized children with confirmed influenza A, 9.6% had respiratory failure and 0.9% died. These findings can be compared with the disease severity of subsequent waves of the 2009 novel influenza A(H1N1) pandemic.
authors.affiliation: Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Miroballi
authors.forename: J Scott
authors.initials: JS
authors.lastname: Baird
authors.forename: Sheemon
authors.initials: S
authors.lastname: Zackai
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Cannon
authors.forename: Maria
authors.initials: M
authors.lastname: Messina
authors.forename: Thyyar
authors.initials: T
authors.lastname: Ravindranath
authors.forename: Robert
authors.initials: R
authors.lastname: Green
authors.forename: Phyllis
authors.initials: P
authors.lastname: Della-Latta
authors.forename: Stephen
authors.initials: S
authors.lastname: Jenkins
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Greenwald
authors.forename: E Yoko
authors.initials: EY
authors.lastname: Furuya
authors.forename: Philip L
authors.initials: PL
authors.lastname: Graham
authors.forename: F Meridith
authors.initials: FM
authors.lastname: Sonnett
authors.forename: Shari
authors.initials: S
authors.lastname: Platt
authors.forename: Patricia
authors.initials: P
authors.lastname: Delamora
authors.forename: Lisa
authors.initials: L
authors.lastname: Saiman
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006764:Hospitals, Community / Q000706:statistics & numerical data; D006785:Hospitals, University / Q000706:statistics & numerical data; D006786:Hospitals, Urban / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology*; D008297:Male; D009519:New York City / Q000453:epidemiology; D012189:Retrospective Studies