title: [Diagnosis of a human rabies case in Jujuy, 2008].
abstract: On July 22, 2008, a previously healthy 8 years old boy from Jujuy, Argentina, died of encephalitis later confirmed as rabies. Diagnosis was made on the basis rabies-specific antibodies presence in a serum sample and it was confirmed by detection of the viral antigens in brain necropsy using the immunofluorescent test. Antigenic characterization identified dog as source of infection. Molecular analysis recognized the same genetic variant circulating in Jujuy since 2003. This report presents the patient's clinical course and the epidemiologic investigation that revealed a dog bite 60 days before the illness onset and the lack of rabies treatment.
authors.affiliation: Instituto de Zoonosis Dr. Luis Pasteur, Jujuy, Argentina.
authors.forename: Federico
authors.initials: F
authors.lastname: Gury-Dohmen
authors.forename: Berta
authors.initials: B
authors.lastname: Baspineiro
authors.forename: Graciela
authors.initials: G
authors.lastname: Gury
authors.forename: Leila
authors.initials: L
authors.lastname: Martínez
authors.forename: María Rosa
authors.initials: MR
authors.lastname: Miranda
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Cisterna
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001733:Bites and Stings / Q000150:complications*; D001921:Brain / Q000473:pathology; D002648:Child; D004285:Dogs; D018792:Encephalitis, Viral / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D011818:Rabies / Q000276:immunology / Q000473:pathology*; D011820:Rabies virus / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000956:Antigens, Viral