title: Severe pneumonia associated with pandemic (H1N1) 2009 outbreak, San Luis Potosí, Mexico.
abstract: We describe the clinical characteristics and outcomes of adults hospitalized with pneumonia during the pandemic (H1N1) 2009 outbreak. Patients admitted to a general hospital in San Luis Potosí, Mexico, from April 10 through May 11, 2009, suspected to have influenza virus-associated pneumonia were evaluated. We identified 50 patients with suspected influenza pneumonia; the presence of influenza virus was confirmed in 18: 11 with pandemic (H1N1) 2009 virus, 5 with unsubtypeable influenza A virus, 1 with seasonal influenza A virus (H3N2), and 1 in whom assay results for seasonal and pandemic (H1N1) 2009 viruses were positive. Eighteen patients were treated in the intensive care unit, and 10 died. During the pandemic (H1N1) 2009 outbreak, severe pneumonia developed in young adults who had no identifiable risk factors; early diagnosis and treatment of influenza virus infections may have a determinant role in outcome.
authors.affiliation: Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico. agomez.cer@prodigy.net.mx
authors.forename: Alejandro
authors.initials: A
authors.lastname: Gómez-Gómez
authors.forename: Martin
authors.initials: M
authors.lastname: Magaña-Aquino
authors.forename: Christian
authors.initials: C
authors.lastname: Garcia-Sepúlveda
authors.forename: Uciel R
authors.initials: UR
authors.lastname: Ochoa-Pérez
authors.forename: Reynaldo
authors.initials: R
authors.lastname: Falcón-Escobedo
authors.forename: Andreu
authors.initials: A
authors.lastname: Comas-García
authors.forename: Saray
authors.initials: S
authors.lastname: Aranda-Romo
authors.forename: Hugo I
authors.initials: HI
authors.lastname: Contreras-Treviño
authors.forename: Paulina V
authors.initials: PV
authors.lastname: Jimenéz-Rico
authors.forename: Mario A
authors.initials: MA
authors.lastname: Banda-Barbosa
authors.forename: Félix
authors.initials: F
authors.lastname: Dominguez-Paulin
authors.forename: J Mario
authors.initials: JM
authors.lastname: Bernal-Blanco
authors.forename: Luis F
authors.initials: LF
authors.lastname: Peréz-González
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Noyola
mesh_terms: D000328:Adult; D000368:Aged; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D053122:Influenza A Virus, H3N2 Subtype; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D055815:Young Adult