title: Paralemnolins J-P, new sesquiterpenoids from the soft coral Paralemnalia thyrsoide.
abstract: Six new sesquiterpenoids, paralemnolins J-O (1-6), along with one novel norsesquiterpenoid, paralemnolin P (7), have been isolated from the soft coral Paralemnalia thyrsoides. The structures of metabolites 1-7 were established on the basis of extensive NMR study and chemical methods. The structure of 5 was further confirmed by a single-crystal X-ray analysis. Cytotoxicity of these metabolites toward a limited panel of cancer cell lines also is described.
authors.affiliation: Department of Cosmetic Science, Chia-Nan University of Pharmacy and Science, Taiwan.
authors.forename: Guey-Horng
authors.initials: GH
authors.lastname: Wang
authors.forename: Ho-Cheng
authors.initials: HC
authors.lastname: Huang
authors.forename: Jui-Hsin
authors.initials: JH
authors.lastname: Su
authors.forename: Yang-Chang
authors.initials: YC
authors.lastname: Wu
authors.forename: Jyh-Horng
authors.initials: JH
authors.lastname: Sheu
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000032:analysis* / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D012717:Sesquiterpenes; C547780:paralemnolin