CLC transport proteins in plants.
Nitrate compartmentalization in intracellular organelles has been long recognized as critical for plant physiology but the molecular identity of the proteins involved remained unclear for a long time. In Arabidopsis thaliana, AtClC-a has been recently shown to be a NO(3)(-)/H(+) antiporter critical for nitrate transport into the vacuoles. AtClC-a is a member of the CLC protein family, whose animal and bacterial members, comprising both channels and H(+)-coupled antiporters, have been previously implicated exclusively in Cl(-) transport. Despite the different NO(3)(-) over Cl(-) selectivity of AtClC-a compared to the other CLC antiporters, it has similar transport properties. Other CLC homologues have been cloned in Arabidopsis, tobacco, rice and soybean.
Zifarelli
G
G
Istituto di Biofisica, CNR, Via De Marini 6, I-16149 Genova, Italy. zifarelli@ge.ibf.cnr.it
Pusch
M
M
D000818:Animals; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015220:Calcium Channels / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D006801:Humans; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D010944:Plants; D012441:Saccharomyces cerevisiae / Q000235:genetics
D001426:Bacterial Proteins; D015220:Calcium Channels; D010940:Plant Proteins