title: Use of CE for the determination of binding constants.
abstract: In the past two decades, CE has been used frequently for the measurement of apparent binding/association constants. CE has numerous advantages, including short analysis times, low sample consumption, simplicity of operation, etc. This review provides a fundamental introduction to binding theory and then summarizes recent applications and advances in the field of CE-based methods for the evaluation of molecular association. The time period for this survey is from 2002 (when our previous review was published) to the present.
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX, USA.
authors.forename: Chunxia
authors.initials: C
authors.lastname: Jiang
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Armstrong
mesh_terms: D003198:Computer Simulation; D019075:Electrophoresis, Capillary / Q000379:methods*; D007700:Kinetics; D008904:Miniaturization; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011506:Proteins