title: Nanotoxicology: a personal perspective.
abstract: Nanoparticles arise from a wide variety of natural and man-made sources and have a diverse array of biological, chemical, and physical properties. The toxicity of these particles can be roughly divided into two categories: 1) the enhanced delivery of toxic agents 2) toxicity induced the properties of the particle itself. The use of nanoparticles to provide enhanced delivery of chemotherapeutics is presented followed by a discussion of the size-based effects of electron transfer and physical membrane disruption.
authors.affiliation: Chemistry Department, Graham Environmental Sustainability Institute, University of Michigan, Ann Arbor, MI 48109-1055, USA. mbanasza@umich.edu
authors.forename: Mark M Banaszak
authors.initials: MM
authors.lastname: Holl
mesh_terms: D000818:Animals; D015386:Hazardous Substances / Q000008:administration & dosage; D006801:Humans; D049329:Nanostructures / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000633:toxicity*
chemical_list: D015386:Hazardous Substances