title: Clofarabine-induced capillary leak syndrome in a child with refractory acute lymphoblastic leukemia.
abstract: Clofarabine has significant efficiency in children with relapsed or refractory leukemia. In previous pediatric trials, various adverse effects have been described. In this case, we report a child with refractory acute lymphoblastic leukemia who developed fatal capillary leak syndrome during clofarabine therapy.
authors.affiliation: Departments of Pediatric Hematology, Uludag University, Bursa, Turkey. baytanbirol@yahoo.com
authors.forename: Birol
authors.initials: B
authors.lastname: Baytan
authors.forename: Ozlem
authors.initials: O
authors.lastname: Ozdemir
authors.forename: Adalet Meral
authors.initials: AM
authors.lastname: Gunes
authors.forename: Osman
authors.initials: O
authors.lastname: Dönmez
mesh_terms: D000227:Adenine Nucleotides / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001087:Arabinonucleosides / Q000009:adverse effects*; D019559:Capillary Leak Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D002648:Child; D000077866:Clofarabine; D005260:Female; D006440:Hemofiltration; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*
chemical_list: D000227:Adenine Nucleotides; D000970:Antineoplastic Agents; D001087:Arabinonucleosides; D000077866:Clofarabine