title: [The safety and efficacy of neoadjuvant chemotherapy for patients with hepatic colorectal cancer metastases].
abstract: The aim of this study is to investigate the safety and efficacy of neoadjuvant chemotherapy for patients with hepatic colorectal cancer metastases who underwent hepatic resection. Surgical complications and survival rates of the patients with/without neoadjuvant chemotherapy were analyzed. Neoadjuvant chemotherapy was not associated with sever surgical complications after hepatic resection. Postoperative survival rate of the patients with neoadjuvant chemotherapy was not superior to that of patients without neoadjuvant chemotherapy. Neoadjuvant chemotherapy for patients with hepatic colorectal cancer metastases who underwent hepatic resection is safe, but further studies are required to clarify its efficacy.
authors.affiliation: Department of Surgery, National Hospital Organization, Osaka National Hospital.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Shoji
authors.initials: S
authors.lastname: Nakamori
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsujie
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Kurokawa
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yasui
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ikenaga
authors.forename: Michihiko
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hirao
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fujitani
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Mishima
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Tsujinaka
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy