[A case of rectal cancer successfully treated by multidisciplinary strategy for liver and pulmonary metastases].
We report a case of rectal cancer with distant metastases, which was successfully treated with multidisciplinary treatments. The 60s female underwent an abdomino-perineal resection (APR) for low rectal cancer. One year after the APR, two hepatic metastases were found and initially treated by radiofrequency ablation and later by hepatectomy. One month after the hepatectomy, three pulmonary metastases of 10 mm in diameter were found in the right lung. Several regimens of chemotherapy (S-1, CPT-11 and FOLFOX6) were performed. After 3 years of chemotherapy, pulmonary metastases re- grew in size but no new lesion developed. Pneumonectomy was performed to remove all metastatic tumors. A half year after the initial pneumonectomy, a new metastasis was found in the left lung, which was again removed by surgery after 6 months of observation. Postoperative course was uneventful, and she is alive without recurrence for 7 years since the initial rectal surgery.
Okazaki
Satoshi
S
Department of Surgical Oncology, and Graduate School, Tokyo Medical and Dental University.
Uetake
Hiroyuki
H
Yano
Makoto
M
Ishiguro
Megumi
M
Kobayashi
Hirotoshi
H
Ishikawa
Toshiaki
T
Iida
Satoru
S
Higuchi
Tetsuro
T
Yasuno
Masamichi
M
Enomoto
Masayuki
M
Sugihara
Kenichi
K
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017115:Catheter Ablation; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008175:Lung Neoplasms / Q000556:secondary* / Q000628:therapy*; D008875:Middle Aged; D011013:Pneumonectomy; D012004:Rectal Neoplasms / Q000473:pathology*