title: [Antibody databases: IMGT, a French platform of world-wide interest].
abstract: IMGT, the international ImMunoGeneTics information system, was created in 1989 in Montpellier by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM) headed by the Professors Marie-Paule and Gérard Lefranc (University Montpellier 2 and CNRS). IMGT is specialized in the sequences, structures and genetic data of the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibilité complex (MHC), proteins of the IgSF and MhcSF superfamilies, and related proteins of the immune system. The data analysis and the standardization of the annotation are based on IMGT-ONTOLOGY, the first ontology in the domain. IMGT is to-day the international reference system in immunogenetics and immunoinformatics, used in fundamental, medical and biotechnological research and, in particular, in antibody -engineering and humanization.
authors.affiliation: Université Montpellier 2, IMGT, LIGM, Institut de génétique humaine, UPR CNRS 1142, 141, rue de la Cardonille, 34396 Montpellier cedex 5, France. Marie-Paule.Lefranc@igh.cnrs.fr
authors.forename: Marie-Paule
authors.initials: MP
authors.lastname: Lefranc
mesh_terms: D000818:Animals; D000906:Antibodies / Q000737:chemistry* / Q000235:genetics / Q000276:immunology; D030541:Databases, Genetic; D030562:Databases, Protein; D005602:France; D006680:HLA Antigens / Q000737:chemistry / Q000235:genetics / Q000276:immunology; D006649:Histocompatibility Antigens / Q000737:chemistry / Q000235:genetics / Q000276:immunology; D006801:Humans; D007125:Immunogenetics / Q000458:organization & administration*; D007136:Immunoglobulins / Q000737:chemistry / Q000235:genetics / Q000276:immunology; D007255:Information Services / Q000458:organization & administration*; D007391:International Cooperation; D020407:Internet; D005810:Multigene Family; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry / Q000235:genetics / Q000276:immunology; D009626:Terminology as Topic; D014495:Universities / Q000458:organization & administration
chemical_list: D000906:Antibodies; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D007136:Immunoglobulins; D011948:Receptors, Antigen, T-Cell