title: Sphenoid wing meningioma and glioblastoma multiforme in collision - case report and review of the literature.
abstract: The coexistence of two histologically different primary tumours in the same brain region is relatively rare. The situation where these tumours in collision appear in an area of a previously excised meningioma is even more rare and only two cases have been reported so far. We present the third case of a 73-year-old woman who underwent an uneventful excision of a right sphenoid wing meningioma. She was re-admitted 3 years later due to reappearance of a tumour in the area adjacent to the previously excised meningioma. Histological diagnosis revealed a collision tumour of a glioblastoma multiforme and a fibrillary meningioma. The coincidence of these two different neoplasms in the same location at the same time 3 years after surgical removal of a meningioma leads us to speculate on the pathogenesis, and to review the literature regarding this particular issue.
authors.affiliation: Department of Neurosurgery, Athens Army General Hospital, Greece. aristotelis.mitsos@wolfson-oxford.com
authors.forename: Aristotelis P
authors.initials: AP
authors.lastname: Mitsos
authors.forename: Evangelos A
authors.initials: EA
authors.lastname: Konstantinou
authors.forename: Theofanis G
authors.initials: TG
authors.lastname: Fotis
authors.forename: Spiridon A
authors.initials: SA
authors.lastname: Lafazanos
authors.forename: George
authors.initials: G
authors.lastname: Kontogeorgos
authors.forename: Nikolaos V
authors.initials: NV
authors.lastname: Georgakoulias
mesh_terms: D000368:Aged; D005260:Female; D005909:Glioblastoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008579:Meningioma / Q000473:pathology* / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D012888:Skull Neoplasms / Q000473:pathology; D016896:Treatment Outcome