Two new guaiane-type sesquiterpenoids from the fruits of Daucus carota L.
Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cytotoxic effects against two human gastric cancer cell lines BGC-823 and AGS.
Fu
Hong-wei
HW
Department of Biomedical Engineering, Zhejiang University, The Key Laboratory of Biomedical Engineering of the Ministry of Education, Hangzhou, PR China.
Zhang
Lin
L
Yi
Tao
T
Feng
Yu-lin
YL
Tian
Jing-kui
JK
D045744:Cell Line, Tumor; D018552:Daucus carota / Q000737:chemistry*; D005638:Fruit; D006801:Humans; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D045789:Sesquiterpenes, Guaiane / Q000737:chemistry / Q000302:isolation & purification*; D013274:Stomach Neoplasms
D010936:Plant Extracts; D045789:Sesquiterpenes, Guaiane; C554310:daucuside; C554311:daucusol