[A case of liver metastasis of rectal cancer demonstrating complete response for more than two years to mFOLFOX6].
A man in his fifties with rectal cancer underwent low anterior resection in another Hospital in January 2006. He was finally diagnosed with Stage III a (pA, pN1, H0, P0). The patient who had postoperative complication such as ruptured suture left the hospital in May 2006, when he was detected with multiple liver metastases and was referred to our hospital for systemic chemotherapy. Systemic chemotherapy with mFOLFOX6 was performed from May 2006. Grade 3 diarrhea and grade 2 peripheral neuropathy, nausea and vomiting were observed. After 6 courses of mFOLFOX6, MRI revealed metastasis had been disappeared and levels of CEA and CA19-9 were decreased below normal. The treatment has been discontinued. Recurrence was not observed for 30 months.
Miyo
Masaaki
M
Department of Surgery, Minoh City Hospital.
Kato
Takeshi
T
Miyake
Yasuhiro
Y
Kato
Aya
A
Sakamoto
Takuya
T
Doi
Takashi
T
Hoshi
Minako
M
Makari
Yoichi
Y
Oshima
Satoshi
S
Iijima
Shouhei
S
Kurokawa
Eiji
E
Kikkawa
Nobuteru
N
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000473:pathology*; D016896:Treatment Outcome
D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil