Surgical outcome of 2-stage (posterior and anterior) surgical treatment using spinal instrumentation for tuberculous spondylitis.
METHODS
A prospective study on the clinical outcomes in patients with tuberculous spondylitis treated by a 2-stage operation (posterior and anterior) using posterior spinal instrumentation.


OBJECTIVE
To evaluate the clinical outcomes of the 2-stage surgical treatment (first stage: placement of posterior instrumentation and second stage: anterior debridement and bone grafting) for tuberculous spondylitis.


BACKGROUND
There have been few reports describing the effects of 2-stage surgical treatment for tuberculous spondylitis.


METHODS
Ten patients (5 men and 5 women) with tuberculous spondylitis were treated by 2-stage operations. Age at the initial operation was 64.6+/-14.8 years (average+/-SD) (range: 47 to 83 y). The clinical outcomes were evaluated before and after the surgery in terms of hematologic examination, pain level, and neurologic status. Bone fusion and changes in sagittal alignment were examined radiographically.


RESULTS
All patients showed suppression of infection, bony fusion, relief of pain, and recovery of neurologic function. No significant changes were observed in kyphosis angle at the final follow-up. There were no incidences of severe complications or recurrence.


CONCLUSIONS
Our results showed that posterior and anterior 2-stage surgical treatment for tuberculous spondylitis is a viable surgical option for cases in which conservative treatment has failed. However, the changes in sagittal alignment showed that this strategy provides limited kyphosis correction.
Hirakawa
Akihiro
A
Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Miyamoto
Kei
K
Masuda
Takahiro
T
Fukuta
Shoji
S
Hosoe
Hideo
H
Iinuma
Nobuki
N
Iwai
Chizuo
C
Nishimoto
Hirofumi
H
Shimizu
Katsuji
K
D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use; D001416:Back Pain / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D016025:Bone Transplantation; D005260:Female; D006801:Humans; D016268:Internal Fixators; D007738:Kyphosis / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D011446:Prospective Studies; D011859:Radiography; D019651:Plastic Surgery Procedures; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014399:Tuberculosis, Spinal / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*
D000995:Antitubercular Agents