Nanotoxicology: a personal perspective.
Nanoparticles arise from a wide variety of natural and man-made sources and have a diverse array of biological, chemical, and physical properties. The toxicity of these particles can be roughly divided into two categories: 1) the enhanced delivery of toxic agents 2) toxicity induced the properties of the particle itself. The use of nanoparticles to provide enhanced delivery of chemotherapeutics is presented followed by a discussion of the size-based effects of electron transfer and physical membrane disruption.
Holl
Mark M Banaszak
MM
Chemistry Department, Graham Environmental Sustainability Institute, University of Michigan, Ann Arbor, MI 48109-1055, USA. mbanasza@umich.edu
D000818:Animals; D015386:Hazardous Substances / Q000008:administration & dosage; D006801:Humans; D049329:Nanostructures / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000633:toxicity*
D015386:Hazardous Substances