title: [A case of successful control of recurrent duodenal carcinoma receiving paclitaxel].
abstract: We have experienced a case of successful control of recurrent duodenal carcinoma receiving paclitaxel chemotherapy. A 61-year-old woman with epigastralgia was diagnosed with pyloric gastric carcinoma upon upper gastrointestinal endoscopy and biopsy. Distal gastrectomy with D2 dissection was performed. However, at the resected organ, the lesion was on the duodenum. So, we additionally resected the anal edge. And 13a, 13b, 12a, p lymph nodes were dissected for duodenal carcinoma. Later, the CEA level was increased, and abdominal CT scan showed swelling of paraaortic lymph nodes. Recurrence of the duodenal carcinoma was diagnosed in February 2007, and S-1 administration was begun. But, we dosed down with S-1 due to severe diarrhea. In spite of combined S-1 and CPT-11 chemotherapy, the CEA level increased, and lymph nodes were getting larger. She then underwent the paclitaxel chemotherapy during the 5 months without severe side effects. The CEA level decreased significantly and metastatic lymph nodes were reduced observed by CT scan. Paclitaxel chemotherapy is effective for duodenal cancer.
authors.affiliation: Department of Surgery, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Keita
authors.initials: K
authors.lastname: Ookubo
authors.forename: Masahisa
authors.initials: M
authors.lastname: Ootsuka
authors.forename: Hironori
authors.initials: H
authors.lastname: Akitake
authors.forename: Takayo
authors.initials: T
authors.lastname: Maekawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yoshioka
authors.forename: Naoki
authors.initials: N
authors.lastname: Hama
authors.forename: Masaki
authors.initials: M
authors.lastname: Kashiwazaki
authors.forename: Masaki
authors.initials: M
authors.lastname: Tsujie
authors.forename: Muneharu
authors.initials: M
authors.lastname: Konishi
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Fujimoto
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002334:Carnitine O-Palmitoyltransferase / Q000627:therapeutic use; D004338:Drug Combinations; D004379:Duodenal Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D010094:Oxonic Acid / Q000627:therapeutic use; D017239:Paclitaxel / Q000627:therapeutic use*; D005641:Tegafur / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002334:Carnitine O-Palmitoyltransferase; D017239:Paclitaxel