title: [Puncture hystobiopsy with tissue telomerase activity measurement in preoperative thyroid nodes diagnostics].
abstract: Demonstrated, that puncture thyroid hystobiopsy is safe and informative method of preoperative thyroid nodes diagnostics. Telomerase activity in tissue samples was significantly higher in case of malignant thyroid disease, although a positive correlation of telomerase activity was also with the amount of lymphocytes in bioptates. Combination of thyroid hystobiopsy with tissue telomerase activity measurement proved to be an effective means of preoperative diagnostic of patients with nodular goiter.
authors.forename: T V
authors.initials: TV
authors.lastname: Khorobrykh
authors.forename: A I
authors.initials: AI
authors.lastname: Glukhov
authors.forename: L I
authors.initials: LI
authors.lastname: Ippolitov
authors.forename: D V
authors.initials: DV
authors.lastname: Zhulikov
authors.forename: I I
authors.initials: II
authors.lastname: Bykov
authors.forename: I A
authors.initials: IA
authors.lastname: Marchenko
authors.forename: R M
authors.initials: RM
authors.lastname: Nurutdinov
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods*; D003937:Diagnosis, Differential; D004586:Electrophoresis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods*; D019098:Telomerase / Q000378:metabolism*; D013961:Thyroid Gland / Q000201:enzymology / Q000473:pathology / Q000601:surgery; D016606:Thyroid Nodule / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy / Q000379:methods
chemical_list: D019098:Telomerase