Triterpenoid from Lycopodium obscurum L.
To study the triterpenoid constituents from air-dried whole plants of Lycopodium obscurum L., the constituents were isolated by normal-phase and reverse-phase silica gel column chromatography from the EtOAc extract. Their structures were elucidated on the basis of spectral analysis. Five triterpenoids were purified and identified as 3beta, 19alpha-dihydroxy-20beta-acetate-serrat-14-en-21beta-ol (1), serratenediol (2), alpha-onocerin (3), 26-nor-8-oxo-alpha-onocerin (4), (3beta, 8beta, 14alpha, 21alpha)-26, 27-dinoronocerane-3, 8, 14, 21-tetrol (5). Compound 1 is a new serratane-type triterpene and compound 5 is isolated from this plant for the first time.
Deng
Tie-Zhong
TZ
Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China.
Ai
Yong
Y
Chen
Yu
Y
Yang
Guang-Zhong
GZ
D032502:Lycopodium / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
D014315:Triterpenes; C438932:serratenediol; C409888:alpha-onocerin