title: [A case of glycogen storage disease type I with hepatocellular carcinoma].
abstract: The patient was a 55-year-old female. In 1997, she was diagnosed as type-I glycogen storage disease (von Gierke disease). In March 2002, abdominal ultrasound tomography revealed an early enhanced lesion at liver S2, which suspected to a well differentiated hepatocellular carcinoma (HCC) with super-paramagnetic iron oxide (SPIO) enhanced magnetic resonance imaging (MRI). From 2002 to 2006, she received three times trans-arterial chemo-embolization (TACE) at enhanced lesions. But abdominal computer tomography (CT) revealed a 3.6 cm-in diameter early enhanced lesion near this tumor at S2, which was suspected to a diagnosis of recurrent HCC in December 2008. Therefore, she received a partial hepatectomy at S2. This resected specimen was diagnosed as poorly differentiated HCC. This patient is still alive with no recurrence after 6 months from operation. In conclusion, it might be effective for an early detection of recurrent HCC to see the doctor for a long regular checkup, because the growth of HCC with glycogen storage disease would be very slow.
authors.affiliation: Department of Surgery, Suita Municipal Hospital.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Okuda
authors.forename: Hideo
authors.initials: H
authors.lastname: Ota
authors.forename: Koji
authors.initials: K
authors.lastname: Mikami
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Nagase
authors.forename: Ryota
authors.initials: R
authors.lastname: Mukai
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ide
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Maruyama
authors.forename: Kohei
authors.initials: K
authors.lastname: Murata
authors.forename: Hideoki
authors.initials: H
authors.lastname: Yokouchi
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Nagase
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Tamai
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000601:surgery; D005260:Female; D005953:Glycogen Storage Disease Type I / Q000150:complications*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged