[From symptomatic stability to functional recovery in the pharmacological treatment of schizophrenia and unipolar depression].
This work summarizes the efficacy of pharmacotherapy in the chronic course of schizophrenia and unipolar depresion. It is aimed to answer three questions: does it cure these diseases? Does it exert any significant effect on the symptomatic presentation of the disorders? Which is its action on the social dysfunction provoked by schizophrenia or depression? A conceptual analysis of available bibliography was performed. It could be concluded that antypsychotics improve the symptomatic course of schizophrenia, although their efficacy is limited, and that these drugs does not act on the social dysfunction provoked by the disease. With respect to depression, it could be concluded that a significant proportion of patients remain symptomatic despite receiveng adequate treatments. No data about efficacy of pharmacotherapy on the dysfunction resultant from unipolar depression is available.
Wikinski
Silvia
S
Asistencia y Rehabilitación en Salud Mental, 1a Cátedra de Farmacología, Facultad de Medicina, UBA. swikinsk@ffyb.uba.ar
D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D020127:Recovery of Function; D012559:Schizophrenia / Q000188:drug therapy*