Malignant mixed müllerian tumor of the fallopian tube: report of two cases and review of literature.
OBJECTIVE
Malignant mixed müllerian tumors (MMMT) of the female genital tract is rare and it is extremely rare in the fallopian tube, with fewer than 53 cases reported in the literature.


METHODS
We had experienced two cases of MMMT of the fallopian tube. The clinical features, pathologic findings, diagnosis, therapy, and outcome were reviewed.


RESULTS
The clinical features and diagnosis were similar to those of primary carcinoma of the fallopian tube. Histologically, the two patients had homologous and heterologous elements mixed müllerian tumors. Treatment has focused on surgery with postoperative chemotherapy. Prognosis is poor, with fewer than half of patients surviving 2 years.


CONCLUSIONS
MMMT of fallopian tube is an uncommon carcinoma in the female genital tract. Cervical cytology and endometrial curettage could raise the suspicion of a tubal malignancy, but diagnosis is not usually made until the time of surgery. The patient survival will improve after surgery and postoperative chemotherapy.
Shen
Yang-Mei
YM
Department of Pathology, West China Second University Hospital, Sichuan University, No 20, Sect. 3, South People's Road, 610041, Chengdu, Sichuan, People's Republic of China.
Xie
Yu-Ping
YP
Xu
Lian
L
Yang
Kai-Xuan
KX
Yu
Na
N
Yu
Yan
Y
Wang
Jing-Hua
JH
D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005185:Fallopian Tube Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*
D000970:Antineoplastic Agents