title: Immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells.
abstract: Rheumatoid arthritis is a chronic disorder for which there is no known cure. Concentrating on specific elements of the abnormal immune response that characterizes the disease, scientists are reaching into biotechnology's bag of tricks to develop immunotherapeutic techniques. This paper will present some advances in the immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells.
authors.affiliation: Department of Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, People's Republic of China. guangjie_chen@163.com
authors.forename: Guangjie
authors.initials: G
authors.lastname: Chen
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D015703:Antigens, CD / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000276:immunology* / Q000628:therapy*; D060908:CTLA-4 Antigen; D024043:Collagen Type II / Q000627:therapeutic use; D016207:Cytokines / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance; D007167:Immunotherapy; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000637:transplantation
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; D024043:Collagen Type II; D016207:Cytokines