title: Hemodynamic support using the Impella 2.5 catheter system during high-risk percutaneous coronary intervention in a patient with severe aortic stenosis.
abstract: The Impella 2.5 catheter is a percutaneously implanted left ventricular assist device cleared by the Food and Drug Administration to provide circulatory support for up to 6 hours. The presence of aortic stenosis is deemed to be a contraindication to its use, and ongoing clinical trials exclude patients with an aortic valve area of 1.5 cm(2) or less. We describe a case of severe aortic stenosis with an estimated valve area of 0.9 cm(2) and severe ischemic cardiomyopathy in whom the Impella catheter was successfully used for high-risk multivessel percutaneous coronary intervention.
authors.affiliation: Guthrie Health System, Sayre, Pennsylvania 18840, USA. harjai_kishore@guthrie.org
authors.forename: Kishore J
authors.initials: KJ
authors.lastname: Harjai
authors.forename: William W
authors.initials: WW
authors.lastname: O'Neill
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods; D001021:Aortic Valve / Q000473:pathology; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000628:therapy*; D009202:Cardiomyopathies / Q000473:pathology; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D006333:Heart Failure; D006352:Heart Ventricles; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension; D008297:Male; D017202:Myocardial Ischemia / Q000473:pathology; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D013318:Stroke Volume; D016277:Ventricular Function, Left
chemical_list: D002316:Cardiotonic Agents