Decoding the evolution of a breast cancer genome.
Shah et al have recently reported the first successful sequencing of the entire genome of a solid tumour (Shah et al, 2009). Philippe Bedard and Christos Sotiriou analyse their findings as well as the challenges of applying the study of cancer genomes to clinical cancer care.
Bedard
Philippe L
PL
Department of Medical Oncology, Jules Bordet Institute, Brussels, Belgium.
Sotiriou
Christos
C
D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D015894:Genome, Human; D006801:Humans; D009154:Mutation; D017422:Sequence Analysis, DNA