[Prevalence of occult chronic kidney disease and associated variables in a population of patients with type 2 diabetes].
OBJECTIVE
To determine the prevalence of occult chronic kidney disease (CKD) and the associated clinical variables in patients with type 2 diabetes mellitus (DM-2).


METHODS
Observational, laboratory and cross-sectional study of patients with DM-2 from primary care settings. Demographic and anthropometric data, previous illnesses and measures of cardiovascular risk and kidney function were collected from electronic medical records. We determined the prevalence of occult CKD defined as patients with normal values of plasma creatinine (Cr) and reduced glomerular filtration rate (GFr) (< 60 ml/min/1,73 m(2)). The GFr was determined by the Modification of Diet in Renal Disease (MDRD) equation.


RESULTS
The sample consisted of 3,197 patients, the mean age was 67.7 years (SD = 11.7) and 53.9% were men. The prevalence of CKD according to the MDMR values was 16.6% (n = 532), of which 60.3% (n = 321) corresponded to occult CKD. 6.6% (n = 211) of the participants had CKD with high Cr values. Multivariate analysis showed an association of occult CKD with female sex (OR = 2.7; CI 95% = 1,83-3,99). Occult CKD was associated with age, blood pressure higher than 150/100 mm/Hg and with a history of ischemic heart disease, heart failure, peripheral arterial disease and dyslipemia.


CONCLUSIONS
The prevalence of CKD is 16.6%, of which 60.3% (n = 321) corresponds to occult CKD. Female sex is associated with the presence of occult CKD.
Rodríguez-Poncelas
Antonio
A
Area Bàsica de Salut d'Anglès, Institut d'Assistència Sanitària de Girona, Girona, España. antoni.rodriguez@ias.scs.es
Quesada Sabate
Miquel
M
Coll De Tuero
Gabriel
G
Caula Ros
Jacint
J
Gelada-Batlle
Esther
E
Gómez-Marcos
Manuel Angel
MA
Garre-Olmo
Josep
J
García-Ortiz
Luis
L
Comalada Daniel
Carme
C
Ramos Blanes
Rafel
R
D000368:Aged; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D015995:Prevalence