title: Cationic N-confused porphyrin derivative as a better molecule scaffold for G-quadruplex recognition.
abstract: One N-confused porphyrin derivative was prepared and its first observation that it could stabilize G-quadruplex and possessed high selectivity over duplex DNA was made, furthermore, it was also proved to possess the capacity to induce a structural transition from the antiparallel to the mixed-type hybrid G-quadruplex structure.
authors.affiliation: College of Chemistry and Molecular Sciences, State Key Laboratory of Virology, Minist Educ, Key Lab Biomed, Wuhan University, Hubei, Wuhan 430072, PR China.
authors.forename: Yuhao
authors.initials: Y
authors.lastname: Du
authors.forename: Dan
authors.initials: D
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Ming
authors.initials: M
authors.lastname: Zhang
authors.forename: Yangyang
authors.initials: Y
authors.lastname: Zhou
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
mesh_terms: D001483:Base Sequence; D001665:Binding Sites; D002412:Cations / Q000737:chemistry / Q000494:pharmacology; D004247:DNA / Q000737:chemistry; D054856:G-Quadruplexes / Q000187:drug effects*; D006801:Humans; D008958:Models, Molecular; D011166:Porphyrins / Q000737:chemistry* / Q000494:pharmacology*; D016615:Telomere / Q000737:chemistry / Q000187:drug effects
chemical_list: D002412:Cations; D011166:Porphyrins; D004247:DNA