title: Mixed testicular germ cell tumor presenting as metastatic pure choriocarcinoma involving multiple lung metastases that was effectively treated with high-dose chemotherapy.
abstract: Choriocarcinoma in the testis is very rare, and it represents less than 1% (0.3%) of all the testicular germ cell tumors. It is a particularly aggressive variant of non-seminoma tumor, which is characterized by a high serum beta-HCG level and multiple lung metastases. The optimal management for this disease remains undefined. We report here on a case of choriocarcinoma with multiple lung metastases, and the patient has achieved continuous remission for 2 years after combination chemotherapy of BEP (bleomycin, etoposide and cisplatin) and sequential high-dose chemotherapy with autologous peripheral stem cell rescue.
authors.affiliation: Division of Hematology-Oncology, Department of Internal Medicine, Soonchunhyang University Hospital, Seoul, Korea.
authors.forename: Sang-Cheol
authors.initials: SC
authors.lastname: Lee
authors.forename: Kyoung Ha
authors.initials: KH
authors.lastname: Kim
authors.forename: Sung Han
authors.initials: SH
authors.lastname: Kim
authors.forename: Nam Su
authors.initials: NS
authors.lastname: Lee
authors.forename: Hee Sook
authors.initials: HS
authors.lastname: Park
authors.forename: Jong-Ho
authors.initials: JH
authors.lastname: Won