Microwave-assisted palladium-catalyzed phosphonium coupling of 2(1H)-pyrazinones.
An expedient route for the synthesis of differently substituted 2(1H)-pyrazinones applying a microwave-assisted palladium-catalyzed phosphonium coupling procedure is reported. The method has also been successfully extended to some other tautomerizable heterocycles for efficient C-C cross-coupling.
Mehta
Vaibhav P
VP
Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
Modha
Sachin G
SG
Van der Eycken
Erik V
EV