[Studies on the chemical constituents from Euphorbia chrysocoma].
OBJECTIVE
To study the chemical constituents from the aerial part of Euphorbia chrysocoma.


METHODS
All compounds were isolated and purified by many methods, including siliga gel and reversed phase RP-18 column chromatographies, preparative thin layer chromatography, Sephadex LH-20, and recrystallization. Their structures were mainly elucidated by ESI-MS and NMR spectra and their physical characters.


RESULTS
Six compounds were isolated from the petroleum ether section from 75% ethanol extraction of the material. Their structures were identified as taraxerol (1), epitaraxerol (2), beta-sistosterol (3), beta-sitostenone (4), jolkinolide E (5), and sesamin (6).


CONCLUSIONS
Compounds 1, 2, 4, 5, and 6 are isolated from this plant for the first time.
Jiang
Chun-yong
CY
The College of Life Science, Guizhou University, Guiyang 550025, China. chunyong20@hotmail.com
Mu
Shu-zhen
SZ
Deng
Bin
B
Ge
Yong-hui
YH
Zhang
Jian-xin
JX
Hao
Xiao-jiang
XJ
D004149:Dioxoles / Q000737:chemistry / Q000302:isolation & purification; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D028481:Euphorbia / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification
D004149:Dioxoles; D004224:Diterpenes; D017705:Lignans; D012855:Sitosterols; C095253:jolkinolide E; C025473:gamma-sitosterol; D009828:Oleanolic Acid; C005802:taraxerol; C054125:sesamin