title: Acute cerebrovascular incident caused by septic emboli: a case report.
abstract: Septic embolism is a rare disorder associated with infective endocarditis, urinary tract infections, bone infections, femoral thrombophlebitis and sinusitis. We present a 53-year-old patient with multiple systemic embolism and cerebral infarction resulting from aortal thrombus after surgical treatment of the right fibular malleolar fracture with osteosynthetic material placement. After the surgery, the patient became antisocial, with decreased appetite and substantial weight loss. Computerized tomography scan showed several small hypodense zones in the supratentorial and periventricular region of the brain as well as bilateral pleural effusion, large infarcts of the spleen and right kidney, smaller infarcts of the lower pole of the right kidney, discontinuity of the wall of the thoraco-abdominal aorta and a thrombus present in the distal part of abdominal aorta. The findings primarily indicated septic emboli. The right ankle x-ray showed still present postoperative fracture gap of the right fibular malleolus with reduced bone mineralization but no signs of bone destruction. Control MSCT of the abdomen showed a large spleen abscess of 10x6 cm in size. Due to edema of the right ankle, ultrasonography was performed to reveal a thick content in the joint. The patient was transferred to University Department of Surgery, where splenectomy with evacuation of the perisplenic abscess together with extraction of the osteosynthetic material of the right fibular malleolus was performed. If not promptly diagnosed, septic emboli can cause devastating neurologic damage. In our patient, early diagnosis and intensive physical therapy facilitated almost complete regression of his neurologic deficit.
authors.affiliation: University Department of Neurology, Reference Center for Neurovascular Disorders, Ministry of Health and Social Welfare of Republic of Croatia, Sestre milosrdnice University Hospital, Zagreb, Croatia. sonja.antic@gmail.com
authors.forename: Sonja
authors.initials: S
authors.lastname: Antić
authors.forename: Vesna
authors.initials: V
authors.lastname: Vargek-Solter
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Trkanjec
authors.forename: Sandra
authors.initials: S
authors.lastname: Morović
authors.forename: Tomislav
authors.initials: T
authors.lastname: Breitenfeld
authors.forename: Visnja
authors.initials: V
authors.lastname: Supanc
authors.forename: Davor
authors.initials: D
authors.lastname: Jurisií
authors.forename: Vida
authors.initials: V
authors.lastname: Demarin
mesh_terms: D000208:Acute Disease; D005360:Fibula / Q000293:injuries; D050723:Fractures, Bone / Q000150:complications*; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D013158:Splenic Diseases / Q000150:complications; D020521:Stroke / Q000209:etiology*; D013530:Surgical Wound Infection / Q000150:complications*