Clofarabine-induced capillary leak syndrome in a child with refractory acute lymphoblastic leukemia.
Clofarabine has significant efficiency in children with relapsed or refractory leukemia. In previous pediatric trials, various adverse effects have been described. In this case, we report a child with refractory acute lymphoblastic leukemia who developed fatal capillary leak syndrome during clofarabine therapy.
Baytan
Birol
B
Departments of Pediatric Hematology, Uludag University, Bursa, Turkey. baytanbirol@yahoo.com
Ozdemir
Ozlem
O
Gunes
Adalet Meral
AM
Dönmez
Osman
O
D000227:Adenine Nucleotides / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001087:Arabinonucleosides / Q000009:adverse effects*; D019559:Capillary Leak Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D002648:Child; D000077866:Clofarabine; D005260:Female; D006440:Hemofiltration; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*
D000227:Adenine Nucleotides; D000970:Antineoplastic Agents; D001087:Arabinonucleosides; D000077866:Clofarabine