title: [A case of advanced gastric cancer responding completely treated with S-1 therapy].
abstract: A 61-year-old male complained of easy fatigue. Gastroscopy revealed a gastric carcinoma. CT showed No.3 and No.7 lymph nodes swelling. Distant metastasis was not found. S-1 (120 mg/day) was administered for 28 days followed by 14- day rest as one course. Total gastrectomy was performed for 2 weeks after the chemotherapy. Pathology revealed no cancer cells in the gastric wall and dissected lymph nodes. The pathological effect was judged as Grade 3. This case suggests that S-1 therapy may be useful for elderly patients and patients with poor renal function.
authors.affiliation: Department of Surgery, Chiba Municipal Kaihin Hospital.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Wakatsuki
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yoshioka
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kataoka
authors.forename: Toru
authors.initials: T
authors.lastname: Tonooka
authors.forename: Jun
authors.initials: J
authors.lastname: Kawamoto
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Oeda
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid