Effects of sodium dodecylbenzene sulfonate and sodium dodecyl sulfate on the Mytilus galloprovincialis biomarker system.
The effects of in vivo exposure of Mytilus galloprovincialis to two anionic surfactants (SDBS and SDS) on the molecular biomarker system were studied. After continuous exposure for 72 days, activities/levels of GST, GPx and GSH were significantly higher than in corresponding control groups following exposure to 3.000 mg/L SDS and SDBS. Activities of SOD and CAT were significantly inhibited by experimental SDBS (except CAT in 0.100mg/L group), but not by SDS. Statistical analysis of enzyme activities/levels suggested that there were significant positive relationships between GST and GPx, and negative relationships were found between GSH and CAT, GSH and SOD. Amplified fragment length polymorphism (AFLP) results showed that a greater genotoxic effect was observed for SDBS than for SDS. Based on the above results, the biomarker system of mussels can be affected by the two anionic surfactants (>or=3.000 mg/L); it was more easily affected by SDBS than by SDS.
Liu
Bo
B
Key Laboratory of Marine Ecology & Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China. iocas_liubo@hotmail.com
Yu
Zhiming
Z
Song
Xiuxian
X
Yang
Fei
F
D000818:Animals; D001557:Benzenesulfonates / Q000633:toxicity*; D015415:Biomarkers / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D049878:Mytilus / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D012967:Sodium Dodecyl Sulfate / Q000633:toxicity*; D013482:Superoxide Dismutase / Q000378:metabolism; D013501:Surface-Active Agents / Q000633:toxicity*
D001557:Benzenesulfonates; D015415:Biomarkers; D013501:Surface-Active Agents; D012967:Sodium Dodecyl Sulfate; C001114:dodecylbenzenesulfonic acid; D002374:Catalase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase; D005978:Glutathione