title: Supramolecular synthesis based on a combination of hydrogen- and halogen bonds.
abstract: A family of supramolecular reagents containing two different binding sites, pyridine and amino-pyrimidine, were allowed to react with iodo- or bromo-substituted benzoic acids in order to assemble individual molecules into larger architectures with precise intermolecular interactions, using a combination of hydrogen- and halogen-bonds. The hydrogen-bond based amino-pyrimidine/carboxylic acid or amino-pyrimidinium/carboxylate synthons are responsible for the assembly of the primary structural motif in every case (7/7 times, 100% supramolecular yield), while Icdots, three dots, centeredN, Brcdots, three dots, centeredN, and Icdots, three dots, centeredO, halogen bonds play a structural supporting role by organizing these supermolecules into extended 1-D and 2-D architectures (5/7 times, 71% supramolecular yield). These results illustrate how two different non-covalent interactions can be employed side-by-side in the reliable construction of extended molecular solid-state networks with predictable connectivity and dimensionality.
authors.affiliation: Contribution from the Department of Chemistry, Kansas State University, 111 Willard Hall, Manhattan, Kansas, 66506.
authors.forename: Christer B
authors.initials: CB
authors.lastname: Aakeröy
authors.forename: Nate
authors.initials: N
authors.lastname: Schultheiss
authors.forename: Arbin
authors.initials: A
authors.lastname: Rajbanshi
authors.forename: John
authors.initials: J
authors.lastname: Desper
authors.forename: Curtis
authors.initials: C
authors.lastname: Moore