A framework for diagnosing and classifying intensive care unit-acquired weakness.
Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuromuscular disorders acquired in critical illness.
Stevens
Robert D
RD
Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. rstevens@jhmi.edu
Marshall
Scott A
SA
Cornblath
David R
DR
Hoke
Ahmet
A
Needham
Dale M
DM
de Jonghe
Bernard
B
Ali
Naeem A
NA
Sharshar
Tarek
T
D001510:Bed Rest; D003422:Critical Care / Q000379:methods; D016638:Critical Illness / Q000145:classification*; D004185:Disability Evaluation; D006801:Humans; D007362:Intensive Care Units; D018908:Muscle Weakness / Q000145:classification* / Q000175:diagnosis; D009460:Neurologic Examination / Q000379:methods; D009468:Neuromuscular Diseases / Q000145:classification* / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control