title: [Recent advances in the applications of ultrasonic microbubbles as gene or drug vectors].
abstract: With the research and application of the new ultrasound microbubble contrast agents, ultrasonic microbubbles can not only help to image, but they can also be used as genes or drug carriers. The microbubbles as genes or drug carriers can pass across the endothelial cell barrier and release genes and drug under the action of ultrasound field, which achieve target treatment effect. Based on the relevant materials, the bioeffects, early successes with gene and drug delivery, and potential clinical applications are reviewed.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Shen
authors.forename: Zhong-Gao
authors.initials: ZG
authors.lastname: Gao
authors.forename: Natalya
authors.initials: N
authors.lastname: Rapoport
mesh_terms: D004337:Drug Carriers; D016503:Drug Delivery Systems; D005822:Genetic Vectors; D045423:Microbubbles; D049329:Nanostructures; D014465:Ultrasonics
chemical_list: D004337:Drug Carriers