title: Intravascular large B-cell lymphoma presenting pulmonary arterial hypertension as an initial manifestation.
abstract: We report a 39-year-old man with intravascular large B-cell lymphoma (IVLBCL) who had been treated as a case with pulmonary arterial hypertension (PAH) for one year. After he became worse, diffuse pulmonary (18)F-fluorodeoxyglucose (FDG) uptake in positron emission tomography (PET) suggested the existence of IVLBCL in the lung showing normal CT images. The diagnosis was confirmed with random transbronchial lung biopsy, and he was then successfully treated. Since IVLBCL presenting PAH has been rare and is difficult to diagnose, early application of FDG-PET may provide early recognition of the disorder, leading to a better outcome.
authors.affiliation: Department of Internal Medicine, Toyonaka Municipal Hospital, Toyonaka, Japan. tkkotake@ybb.ne.jp
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kotake
authors.forename: Satoru
authors.initials: S
authors.lastname: Kosugi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Takimoto
authors.forename: Soichi
authors.initials: S
authors.lastname: Nakata
authors.forename: Junko
authors.initials: J
authors.lastname: Shiga
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nagate
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Hironori
authors.initials: H
authors.lastname: Take
authors.forename: Shuichi
authors.initials: S
authors.lastname: Katagiri
mesh_terms: D000328:Adult; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D049268:Positron-Emission Tomography; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*