Highly enantioselective intramolecular copper catalyzed C-H insertion reactions of alpha-diazosulfones.
Excellent enantiocontrol (up to 98% ee) is achieved in copper catalyzed C-H insertions of alpha-diazosulfones to form thiopyrans, with up to 60% ee in C-H insertions leading to sulfolanes.
Flynn
Christopher J
CJ
Department of Chemistry, Analytical and Biological Chemistry Research Facility, University College Cork, Cork, Ireland.
Elcoate
Curtis J
CJ
Lawrence
Simon E
SE
Maguire
Anita R
AR
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003979:Diazonium Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013450:Sulfones / Q000737:chemistry*
D003979:Diazonium Compounds; D013450:Sulfones; D003300:Copper