title: Determinants of health care costs of HIV-positive patients in the Canary Islands, Spain.
abstract: The aims of this study were to estimate medical expenditures on human immunodeficiency virus (HIV) treatment and to identify significant associated variables. We performed a retrospective multi-centre study in the Canary Islands using a sample of 569 patients recruited at outpatient visits. The study examined demographic and clinical variables, health-related quality of life (HRQOL), and health care resources. Clinical data was obtained from medical records and patient interviews. Several empirical models for identifying the relationship between health care costs and independent variables were developed. The greatest expense came from pharmaceutical expenditure (82.1% of direct costs), while hospital costs only represented 4.6% of total expenditure. The data showed a statistically significant association between health care costs and the CD4 count of the previous year. HRQOL was also a significant variable. Therefore, CD4 cell count can be used to predict health care costs in patients. Policymakers could use this information to help guide their decisions in allocating limited health care resources to HIV treatments.
authors.affiliation: Department of Economic Analysis and Finances, University of Castilla la Mancha, Toledo, Spain. Juan.OlivaMoreno@uclm.es
authors.forename: Juan
authors.initials: J
authors.lastname: Oliva-Moreno
authors.forename: Julio
authors.initials: J
authors.lastname: López-Bastida
authors.forename: Pedro
authors.initials: P
authors.lastname: Serrano-Aguilar
authors.forename: Lilisbeth
authors.initials: L
authors.lastname: Perestelo-Pérez
mesh_terms: D000328:Adult; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000191:economics* / Q000635:transmission; D017048:Health Care Costs; D005102:Health Expenditures; D006295:Health Resources / Q000191:economics*; D006801:Humans; D008297:Male; D015233:Models, Statistical; D010045:Outpatients / Q000706:statistics & numerical data; D011788:Quality of Life; D012044:Regression Analysis; D040841:Resource Allocation; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain; D011795:Surveys and Questionnaires