title: [Preoperative second-derivative of photoplethysmography measurement predicts the hemodynamic response to general anaesthesia induction].
abstract: BACKGROUND
  Second-derivative of photoplethysmography (SDPTG) is a non-invasive method for the assessment of structural and functional arterial properties. We studied the hemodynamic responses to induction of anaesthesia and whether SDPTG could be used in predicting these responses.
  
  
  METHODS
  SDPTG was performed in 71 subjects (35 males, 36 females) undergoing general anaesthesia for elective operation. Anaesthesia was inducted with propofol 2 mg x kg(-1), fentanyl 2 microg x kg(-1), vecuronium 0.1 mg x kg(-1), and sevoflurane 3% in a mixture of 100% oxygen.
  
  
  RESULTS
  The SDPTG indices (b/a and d/a values) significantly correlated with the percentage decrease in systolic blood pressure in both genders. Regression equations (x = SDPTG indices, y = percentage of decrease in systolic blood pressure) were as follows: (1) b/a, r(male) = 0.39, P < 0.05, y = 23.26x + 40.67; r(female) = 0.39, P < 0.05, y = 17.95x + 39.61; (2) d/a, r(male) = -0.37, P < 0.05, y = -31.29x + 16.22 and r(female) = -0.48, P < 0.01, y = -34.46x + 18.55.
  
  
  CONCLUSIONS
  These results suggest that preoperative SDPTG is useful in predicting the hemodynamic response to induction of general anaesthesia.
authors.affiliation: Department of Anaesthesiology, Fukushima Medical University School of Medicine, Fukushima 960-1295.
authors.forename: Shinju
authors.initials: S
authors.lastname: Obara
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Imaizumi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ohashi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nakano
authors.forename: Shin-Ichiro
authors.initials: S
authors.lastname: Takahashi
authors.forename: Shiho
authors.initials: S
authors.lastname: Hayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Iida
authors.forename: Masahiko
authors.initials: M
authors.lastname: Akatsu
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Isosu
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D005260:Female; D005283:Fentanyl; D005544:Forecasting; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D008991:Monitoring, Physiologic; D017156:Photoplethysmography; D057234:Preoperative Period; D015742:Propofol; D000077149:Sevoflurane; D014673:Vecuronium Bromide; D055815:Young Adult
chemical_list: D008738:Methyl Ethers; D000077149:Sevoflurane; D014673:Vecuronium Bromide; D005283:Fentanyl; D015742:Propofol