Squamous cell carcinoma arising in mucosal plasmacytosis.
The authors present an unusual case of invasive squamous cell carcinoma (SCC) developing in a pre-existing plasmacytosis of the lip. The roles of chronic inflammation, immunosuppression, and smoking in the pathogenesis of this tumour are briefly discussed. The authors highlight a significant side effect of the use of immunosuppressive drugs in benign conditions.
Pepper
T
T
Queen Alexandra Hospital, Portsmouth, United Kingdom. Tom.pepper@virgin.net
Shekar
K
K
Singh
M
M
Brennan
P A
PA
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary; D002610:Cheek / Q000473:pathology; D006801:Humans; D008047:Lip Diseases / Q000473:pathology*; D008048:Lip Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D008207:Lymphatic Metastasis / Q000473:pathology; D008218:Lymphocytosis / Q000473:pathology*; D008297:Male; D009059:Mouth Diseases / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D037981:Neck Dissection; D020360:Neoadjuvant Therapy; D010950:Plasma Cells / Q000473:pathology*