title: Prevalence of Helicobacter pylori infection in high-school students on Lanyu Island, Taiwan: risk factor analysis and effect on growth.
abstract: OBJECTIVE
  The Yami inhabit Lanyu Island and are the smallest and most primitive aboriginal tribe in Taiwan. Lanyu Island is a closed environment and little information is available on the prevalence of Helicobacter pylori infection there. This study aimed to establish the prevalence of H. pylori infection in high-school students on Lanyu Island and its risk factors and effect on growth.
  
  
  METHODS
  A cross-sectional population-based study was conducted among high-school students to determine the prevalence of H. pylori infection by using the 13C urea breath test. A questionnaire was administered to the recruited population. Relevant personal and socioeconomic data for risk factors of infection were collected. Body height and weight of the recruited adolescents in relation to H. pylori infection were analyzed.
  
  
  RESULTS
  A total of 106 high-school students (55 boys and 51 girls), with a mean age of 14.3 +/- 1.4 years were enrolled. The overall prevalence of H. pylori infection was 54.7%. Those residing in Dongcing village had the highest rate of H. pylori infection (73.3%). There was no difference in the prevalence of H. pylori infection according to sex, ethnicity, socioeconomic level or parental education. Sixty-two students (54.8%) were completely asymptomatic and the others had at least one gastrointestinal symptom. H. pylori infection was asymptomatic in 56.8% and symptomatic in 53.2% of students. There was no significant difference between infected and uninfected children with regard to body weight, height and body mass index.
  
  
  CONCLUSIONS
  The prevalence of H. pylori infection is high among high-school students on Lanyu Island. There is no evidence that infection is related to growth failure.
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, College of Mackay Medicine, Nursing and Management College, National Taiwan University College of Medicine, Taiwan.
authors.forename: Hsin
authors.initials: H
authors.lastname: Chi
authors.forename: Ming-Jong
authors.initials: MJ
authors.lastname: Bair
authors.forename: Ming-Shiang
authors.initials: MS
authors.lastname: Wu
authors.forename: Nan-Chang
authors.initials: NC
authors.lastname: Chiu
authors.forename: Ya-Chun
authors.initials: YC
authors.lastname: Hsiao
authors.forename: Kuan-Yu
authors.initials: KY
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D003430:Cross-Sectional Studies; D005260:Female; D006130:Growth Disorders / Q000209:etiology*; D016481:Helicobacter Infections / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D013624:Taiwan / Q000453:epidemiology