[Bacteriological spectrum of periodontal pocket in patients with coronary heart disease and myocardial infarction].
BACKGROUND
In the last years literature has paid attention to positive correlation between periodontitis and coronary heart disease, acute coronary events, including myocardial infarction. Mechanisms of this relationship are not completely known. One of the research trends for elucidation of these problems are bacteriological studies. The aim of this study was qualitative and quantitative evaluation of bacterial flora of the periodontal pocket in patients with coronary heart disease and myocardial infarction, with co-existing periodontitis.


METHODS
The research included 40 patients, hospitalised in 1st Clinic of Cardiology, Medical University in Gdańsk. Group 1 included 20 patients after myocardial infarction, group 2 of 20 patients with diagnosed coronary heart disease, with many years duration without acute events. Control group encompassed 20 patients of Chair and Department of Periodontology and Oral Mucosa Diseases, Medical University in Gdańsk, without cardiovascular diseases. Inclusion criterion for the study was diagnosed chronic periodontitis in all patients. In clinical evaluation indices: API, SBI, PD and CAL were used. The material for bacteriological research was taken in each patient from 4 periodontal pockets, minimum 5 mm depth. The culture and identification were performed with present principles. Based on the litearture data about potential pathogenicity for periodontium and cardiovascular system, species for analyse were chosen.


RESULTS
Statistical analyse proved equality of evaluated groups and control group in gender, age and estimated clinical indices. In periodontal pockets all patients anaerobic flora dominated, however without significiant differences in species range. Among microaerophilia and streptococci statistical analyse showed significiant differences in frequency of isolation of Actinobacillus actinomycetescomitans and Streptococcus sanguis in group 1 in comparision to group 2 and control group. Quantitative analyse showed no significiant differences between groups for all bacteria species.


CONCLUSIONS
Clinical evaluation showed comparable values of periodontal parameters. The bacteria species Porphyromonas gingivalis, Actinobacillus actinomycetescomitans and Streptococcus sanguis were more often isolated from periodontal pockets in persons after myocardial infarction, statistically significant for A.a. and S.s.
Bochniak
Mariusz
M
Katedra i Zakład Periodontologii i Chorób Błony Sluzowej Jamy Ustnej, Gdańskiego Uniwersytetu Medycznego.
Sadlak-Nowicka
Jadwiga
J
Kedzia
Anna
A
Sobiczewski
Wojciech
W
D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D002908:Chronic Disease; D003327:Coronary Disease / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D010514:Periodontal Pocket / Q000382:microbiology*; D013298:Streptococcus sanguis / Q000302:isolation & purification