title: Use of amniotic membrane transplantation in isolated conjunctival Bowen disease: a case report.
abstract: OBJECTIVE
  To report a case of isolated conjunctival Bowen disease treated with surgical resection and amniotic membrane transplantation.
  
  
  METHODS
  Interventional case report.
  
  
  RESULTS
  A 70-year-old man was admitted to our clinic with a large conjunctival verrucous plaque well-demarcated in the correspondence of the bulbar conjunctiva in the superior quadrant of the left eye with involved limbal and corneal surface. Ophthalmologic examination on slit-lamp examination and color fundus photographs were carried out before surgery and the results were evaluated.
  
  
  CONCLUSIONS
  Treatment options and treatment studies of Bowen disease are difficult because there are a variety of different protocols and the success of the management depends on several factors (body site, lesion size, number of lesions, and thickness). In the conjunctival localization of the lesion, amniotic membrane transplantation appears to be a useful therapeutic choice after surgical resection of the lesion used to reconstruct ocular and conjunctival surface.
authors.affiliation: Department of Ophthalmology, University of Siena, Siena - Italy. ilaria.motolese@libero.it
authors.forename: Ilaria
authors.initials: I
authors.lastname: Motolese
authors.forename: Luigi
authors.initials: L
authors.lastname: Mazzera
authors.forename: Paolo
authors.initials: P
authors.lastname: Frezzotti
authors.forename: Paolo Alfonso
authors.initials: PA
authors.lastname: Motolese
authors.forename: Eduardo
authors.initials: E
authors.lastname: Motolese
mesh_terms: D000368:Aged; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D001913:Bowen's Disease / Q000473:pathology / Q000601:surgery*; D003230:Conjunctival Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D013508:Ophthalmologic Surgical Procedures