For cost effectiveness, real data trumps trial results.
Torres
Christian
C
D003362:Cost-Benefit Analysis / Q000706:statistics & numerical data*; D052246:Cyclooxygenase 2 Inhibitors / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use; D004358:Drug Therapy / Q000191:economics*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*
D052246:Cyclooxygenase 2 Inhibitors