Functional and evolutionary insights from the genomes of three parasitoid Nasonia species.
We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and developmental genetics. Key findings include the identification of a functional DNA methylation tool kit; hymenopteran-specific genes including diverse venoms; lateral gene transfers among Pox viruses, Wolbachia, and Nasonia; and the rapid evolution of genes involved in nuclear-mitochondrial interactions that are implicated in speciation. Newly developed genome resources advance Nasonia for genetic research, accelerate mapping and cloning of quantitative trait loci, and will ultimately provide tools and knowledge for further increasing the utility of parasitoids as pest insect-control agents.
Werren
John H
JH
Richards
Stephen
S
Desjardins
Christopher A
CA
Niehuis
Oliver
O
Gadau
Jürgen
J
Colbourne
John K
JK
Werren
John H
JH
Richards
Stephen
S
Desjardins
Christopher A
CA
Niehuis
Oliver
O
Gadau
Jürgen
J
Colbourne
John K
JK
Beukeboom
Leo W
LW
Desplan
Claude
C
Elsik
Christine G
CG
Grimmelikhuijzen
Cornelis J P
CJ
Kitts
Paul
P
Lynch
Jeremy A
JA
Murphy
Terence
T
Oliveira
Deodoro C S G
DC
Smith
Christopher D
CD
van de Zande
Louis
L
Worley
Kim C
KC
Zdobnov
Evgeny M
EM
Aerts
Maarten
M
Albert
Stefan
S
Anaya
Victor H
VH
Anzola
Juan M
JM
Barchuk
Angel R
AR
Behura
Susanta K
SK
Bera
Agata N
AN
Berenbaum
May R
MR
Bertossa
Rinaldo C
RC
Bitondi
Márcia M G
MM
Bordenstein
Seth R
SR
Bork
Peer
P
Bornberg-Bauer
Erich
E
Brunain
Marleen
M
Cazzamali
Giuseppe
G
Chaboub
Lesley
L
Chacko
Joseph
J
Chavez
Dean
D
Childers
Christopher P
CP
Choi
Jeong-Hyeon
JH
Clark
Michael E
ME
Claudianos
Charles
C
Clinton
Rochelle A
RA
Cree
Andrew G
AG
Cristino
Alexandre S
AS
Dang
Phat M
PM
Darby
Alistair C
AC
de Graaf
Dirk C
DC
Devreese
Bart
B
Dinh
Huyen H
HH
Edwards
Rachel
R
Elango
Navin
N
Elhaik
Eran
E
Ermolaeva
Olga
O
Evans
Jay D
JD
Foret
Sylvain
S
Fowler
Gerald R
GR
Gerlach
Daniel
D
Gibson
Joshua D
JD
Gilbert
Donald G
DG
Graur
Dan
D
Gründer
Stefan
S
Hagen
Darren E
DE
Han
Yi
Y
Hauser
Frank
F
Hultmark
Da
D
Hunter
Henry C
HC
Hurst
Gregory D D
GD
Jhangian
Shalini N
SN
Jiang
Huaiyang
H
Johnson
Reed M
RM
Jones
Andrew K
AK
Junier
Thomas
T
Kadowaki
Tatsuhiko
T
Kamping
Albert
A
Kapustin
Yuri
Y
Kechavarzi
Bobak
B
Kim
Jaebum
J
Kim
Jay
J
Kiryutin
Boris
B
Koevoets
Tosca
T
Kovar
Christie L
CL
Kriventseva
Evgenia V
EV
Kucharski
Robert
R
Lee
Heewook
H
Lee
Sandra L
SL
Lees
Kristin
K
Lewis
Lora R
LR
Loehlin
David W
DW
Logsdon
John M
JM
Lopez
Jacqueline A
JA
Lozado
Ryan J
RJ
Maglott
Donna
D
Maleszka
Ryszard
R
Mayampurath
Anoop
A
Mazur
Danielle J
DJ
McClure
Marcella A
MA
Moore
Andrew D
AD
Morgan
Margaret B
MB
Muller
Jean
J
Munoz-Torres
Monica C
MC
Muzny
Donna M
DM
Nazareth
Lynne V
LV
Neupert
Susanne
S
Nguyen
Ngoc B
NB
Nunes
Francis M F
FM
Oakeshott
John G
JG
Okwuonu
Geoffrey O
GO
Pannebakker
Bart A
BA
Pejaver
Vikas R
VR
Peng
Zuogang
Z
Pratt
Stephen C
SC
Predel
Reinhard
R
Pu
Ling-Ling
LL
Ranson
Hilary
H
Raychoudhury
Rhitoban
R
Rechtsteiner
Andreas
A
Reese
Justin T
JT
Reid
Jeffrey G
JG
Riddle
Megan
M
Robertson
Hugh M
HM
Romero-Severson
Jeanne
J
Rosenberg
Miriam
M
Sackton
Timothy B
TB
Sattelle
David B
DB
Schlüns
Helge
H
Schmitt
Thomas
T
Schneider
Martina
M
Schüler
Andreas
A
Schurko
Andrew M
AM
Shuker
David M
DM
Simões
Zilá L P
ZL
Sinha
Saurabh
S
Smith
Zachary
Z
Solovyev
Victor
V
Souvorov
Alexandre
A
Springauf
Andreas
A
Stafflinger
Elisabeth
E
Stage
Deborah E
DE
Stanke
Mario
M
Tanaka
Yoshiaki
Y
Telschow
Arndt
A
Trent
Carol
C
Vattathil
Selina
S
Verhulst
Eveline C
EC
Viljakainen
Lumi
L
Wanner
Kevin W
KW
Waterhouse
Robert M
RM
Whitfield
James B
JB
Wilkes
Timothy E
TE
Williamson
Michael
M
Willis
Judith H
JH
Wolschin
Florian
F
Wyder
Stefan
S
Yamada
Takuji
T
Yi
Soojin V
SV
Zecher
Courtney N
CN
Zhang
Lan
L
Gibbs
Richard A
RA
D000818:Animals; D001181:Arthropods / Q000469:parasitology; D005075:Biological Evolution; D019175:DNA Methylation; D004251:DNA Transposable Elements; D005260:Female; D022761:Gene Transfer, Horizontal; D017344:Genes, Insect; D049810:Genetic Speciation; D014644:Genetic Variation; D049750:Genome, Insect; D006790:Host-Parasite Interactions; D019476:Insect Proteins / Q000235:genetics / Q000378:metabolism; D007304:Insect Viruses / Q000235:genetics; D007313:Insecta / Q000235:genetics; D008297:Male; D008969:Molecular Sequence Data; D040641:Quantitative Trait Loci; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA; D014862:Wasp Venoms / Q000737:chemistry / Q000633:toxicity; D014863:Wasps / Q000235:genetics* / Q000502:physiology; D020577:Wolbachia / Q000235:genetics
D004251:DNA Transposable Elements; D019476:Insect Proteins; D014862:Wasp Venoms