title: PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.
abstract: In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.
authors.affiliation: Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@helmholtz-muenchen.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Ruepp
authors.forename: Andreas
authors.initials: A
authors.lastname: Kowarsch
authors.forename: Daniel
authors.initials: D
authors.lastname: Schmidl
authors.forename: Felix
authors.initials: F
authors.lastname: Buggenthin
authors.forename: Barbara
authors.initials: B
authors.lastname: Brauner
authors.forename: Irmtraud
authors.initials: I
authors.lastname: Dunger
authors.forename: Gisela
authors.initials: G
authors.lastname: Fobo
authors.forename: Goar
authors.initials: G
authors.lastname: Frishman
authors.forename: Corinna
authors.initials: C
authors.lastname: Montrone
authors.forename: Fabian J
authors.initials: FJ
authors.lastname: Theis
mesh_terms: D000465:Algorithms; D001671:Biochemistry / Q000379:methods; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods*; D004194:Disease / Q000235:genetics; D020869:Gene Expression Profiling; D005796:Genes; D016678:Genome; D006801:Humans; D020407:Internet; D008126:Lod Score; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D008954:Models, Biological; D008957:Models, Genetic
chemical_list: D035683:MicroRNAs