title: Characteristics of metastasis in the breast from extramammary malignancies.
abstract: OBJECTIVE
  Breast metastasis from extramammary neoplasm is rare. We present the cases of metastasis to the breast after review of results in one institute and we want to show the difference of previous report.
  
  
  METHODS
  The surgical and pathology databases of Samsung Medical Center from November 1994 to March 2009 were investigated to identify all patients with a diagnosis of metastasis to the breast.
  
  
  RESULTS
  Thirty-three patients with breast metastases from extramammary neoplasm were studied. Gastric carcinoma was most common metastatic origin in this study. There were four cases with microcalcifications in their metastatic lesions. This is the first report of microcalcification of metastatic lesions to the breast from hepatocellular carcinoma and gastric cancer.
  
  
  CONCLUSIONS
  Pathologic examination and considering known clinical history may be helpful to differentiate the primary breast cancer and metastatic cancer. Metastasis to the breast from an extramammary neoplasm usually indicates disseminated metastatic disease and a poor prognosis. An accurate diagnosis of breast metastases, differentiating primary from metastatic breast carcinoma, is important for proper management.
authors.affiliation: Division of Breast and Endocrine Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, South Korea.
authors.forename: Se Kyung
authors.initials: SK
authors.lastname: Lee
authors.forename: Wan Wook
authors.initials: WW
authors.lastname: Kim
authors.forename: Sung Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Sung Mo
authors.initials: SM
authors.lastname: Hur
authors.forename: Sangmin
authors.initials: S
authors.lastname: Kim
authors.forename: Jae Hyuck
authors.initials: JH
authors.lastname: Choi
authors.forename: Eun Yoon
authors.initials: EY
authors.lastname: Cho
authors.forename: Soo Yeon
authors.initials: SY
authors.lastname: Han
authors.forename: Boo-Kyung
authors.initials: BK
authors.lastname: Hahn
authors.forename: Jun-Ho
authors.initials: JH
authors.lastname: Choe
authors.forename: Jung-Han
authors.initials: JH
authors.lastname: Kim
authors.forename: Jee Soo
authors.initials: JS
authors.lastname: Kim
authors.forename: Jeong Eon
authors.initials: JE
authors.lastname: Lee
authors.forename: Seok Jin
authors.initials: SJ
authors.lastname: Nam
authors.forename: Jung-Hyun
authors.initials: JH
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000556:secondary* / Q000601:surgery; D018567:Breast Neoplasms, Male / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000473:pathology*