title: Human serum albumin coated iron oxide nanoparticles for efficient cell labeling.
abstract: A novel dopamine-plus-HSA (human serum albumin) approach was developed to functionalize iron oxide nanoparticles (IONPs), yielding nanoconjugates that are highly efficient in labeling various types of cell lines, which was demonstrated by in vivo MR imaging on xenograft and focal cerebral ischemia models.
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institute of Health, 31 Center Drive, 31/1C22, Bethesda, MD 20892, USA.
authors.forename: Jin
authors.initials: J
authors.lastname: Xie
authors.forename: Jinhua
authors.initials: J
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Niu
authors.forename: Jing
authors.initials: J
authors.lastname: Huang
authors.forename: Kai
authors.initials: K
authors.lastname: Chen
authors.forename: Xingguo
authors.initials: X
authors.lastname: Li
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000175:diagnosis; D002460:Cell Line; D054022:Cerebrum / Q000473:pathology; D004705:Endocytosis; D005290:Ferric Compounds / Q000032:analysis / Q000737:chemistry; D006801:Humans; D008264:Macrophages / Q000737:chemistry / Q000166:cytology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D051379:Mice; D053758:Nanoparticles / Q000032:analysis / Q000737:chemistry; D051381:Rats; D012709:Serum Albumin / Q000737:chemistry*; D014183:Transplantation, Heterologous
chemical_list: D005290:Ferric Compounds; D012709:Serum Albumin; C000499:ferric oxide