Biotransformation of nicotine by microorganism: the case of Pseudomonas spp.
Several bacterial species are capable of using nicotine, the main alkaloid in tobacco plants, as a substrate for growth. The dominant species include members of two genera, Pseudomonas and Arthrobacter. The degradation pathway and genetic structure of nicotine catabolism in Arthrobacter nicotinovorans were recently reviewed (Brandsch Appl Microbiol Biotechnol 69:493-498, 2006). Here, we present up-to-date information on biodegradation of nicotine by Pseudomonas spp. Species in this genus capable of degrading nicotine are summarized and analyzed phylogenetically. Their metabolic intermediates and nicotine degradation-related genes were summarized, and the nicotine-biotransformation pathways were compared and discussed.
Li
Hongjuan
H
Laboratory for Conservation and Utilization of Bio-Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, People's Republic of China.
Li
Xuemei
X
Duan
Yanqing
Y
Zhang
Ke-Qin
KQ
Yang
Jinkui
J
D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D001673:Biodegradation, Environmental; D009538:Nicotine / Q000737:chemistry / Q000378:metabolism*; D010802:Phylogeny; D011549:Pseudomonas / Q000145:classification* / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity
D001426:Bacterial Proteins; D009538:Nicotine