title: Exposure to indoor allergens and association with allergy symptoms of employees in a work environment.
abstract: Exposure to indoor allergens is an important risk factor for sensitisation and respiratory allergy. The aim of this paper was to evaluate the levels of mite, cat and latex allergens in dust collected from an indoor workplace and to assess whether the exposure to these allergens was associated with the allergy symptoms reported by employees. Sixty dust samples were collected. Allergen concentrations were measured with antibody based ELISAs. All 144 participants compiled a questionnaire exploring possible symptoms of allergy. No association between latex allergen exposure and symptoms was found in spite of the high frequency of latex allergens. Mite allergens were detected in a minority of rooms. Cat allergen was the most important indoor allergen in the sampled workplace and exposure to this allergen could represent a risk for employees.
authors.affiliation: Centro per la Ricerca e la Valutazione dei Prodotti Immunobiologici, Istituto Superiore di Sanità, Rome, Italy. barbara.brunetto@iss.it
authors.forename: Barbara
authors.initials: B
authors.lastname: Brunetto
authors.forename: Sonia
authors.initials: S
authors.lastname: Brescianini
authors.forename: Bianca
authors.initials: B
authors.lastname: Barletta
authors.forename: Cinzia
authors.initials: C
authors.lastname: Butteroni
authors.forename: Daniela
authors.initials: D
authors.lastname: Rotondi
authors.forename: Rosalba
authors.initials: R
authors.lastname: Masciulli
authors.forename: Malaguti
authors.initials: M
authors.lastname: Aliberti
authors.forename: Carlo
authors.initials: C
authors.lastname: Pini
authors.forename: Gabriella
authors.initials: G
authors.lastname: Di Felice
authors.forename: Patrizia
authors.initials: P
authors.lastname: Iacovacci
mesh_terms: D000328:Adult; D016902:Air Pollution, Indoor / Q000009:adverse effects / Q000032:analysis; D000485:Allergens / Q000009:adverse effects / Q000032:analysis*; D000818:Animals; D002415:Cats; D004391:Dust / Q000032:analysis; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology*; D007073:Immunoglobulin E / Q000032:analysis; D020315:Latex Hypersensitivity / Q000453:epidemiology; D008297:Male; D008925:Mites / Q000737:chemistry; D016273:Occupational Exposure / Q000032:analysis*; D012044:Regression Analysis; D013048:Specimen Handling
chemical_list: D000485:Allergens; D004391:Dust; D007073:Immunoglobulin E