Oxidative stress and cognitive longevity.
OBJECTIVE
The potential relation between metabolic activity within the central nervous system and retention of cognitive functioning capacity was assessed.


METHODS
A detailed literature review was conducted and summarized.


RESULTS
A large body of scientific evidence describes the interactions among cognitive activity, oxidative stress, neurodegeneration, neuroprotection, cognitive aging, and retention of cognitive functioning ability.


CONCLUSIONS
Maintenance of redox balance within the central nervous system can forestall cognitive decline and promote cognitive longevity.
Glade
Michael J
MJ
The Nutrition Doctor, Skokie, Illinois, USA. the_nutrition_doctor@yahoo.com
D000108:Acetylcarnitine / Q000378:metabolism / Q000494:pharmacology; D000375:Aging / Q000378:metabolism*; D000818:Animals; D002490:Central Nervous System / Q000378:metabolism*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000517:prevention & control*; D006801:Humans; D008136:Longevity; D008928:Mitochondria / Q000378:metabolism; D019636:Neurodegenerative Diseases / Q000517:prevention & control*; D018384:Oxidative Stress; D010718:Phosphatidylserines / Q000008:administration & dosage / Q000378:metabolism
D010718:Phosphatidylserines; D000108:Acetylcarnitine