title: Patient acceptance of whole-body magnetic resonance angiography: A prospective questionnaire study.
abstract: BACKGROUND
  Whole-body magnetic resonance angiography (WB-MRA) is a noninvasive method for diagnosing the systemic distribution of atherosclerosis. Numerous studies have demonstrated the feasibility and diagnostic performance of WB-MRA, but no studies have investigated patient acceptance of this imaging method.
  
  
  OBJECTIVE
  To measure patient acceptance of WB-MRA compared to the gold standard, digital subtraction angiography (DSA), in patients with peripheral arterial disease (PAD).
  
  
  METHODS
  In a prospective design, 79 consecutive patients (51 male, mean age 67 years) with symptomatic PAD, scheduled to undergo both WB-MRA and DSA, were included. Patient acceptance of each imaging procedure was assessed with a postal questionnaire (13 questions). A five-point rank scale (1, no discomfort; 5, severe discomfort) was used to grade patient discomfort.
  
  
  RESULTS
  One patient was excluded from data analysis (did not undergo DSA). Of the remaining 78 patients, 69 completed the questionnaire (response rate 88%). Overall discomfort scores were higher in DSA compared to WB-MRA (mean 2.1 and 1.7, respectively; P = 0.06). In WB-MRA, overall discomfort was strongly correlated to feeling confined in the MRI system (R = 0.77, P< 0.001). In DSA, discomfort was strongly correlated to arterial puncture (R = 0.66, P< 0.001) and contrast injection (R= 0.65, P< 0.001). Injection of iodinated contrast agent at DSA was graded more uncomfortable than injection of gadolinium-based contrast agent at WB-MRA (mean 2.1 vs. 1.5, respectively; P<0.001). Sixty-two patients (90%) were willing to repeat WB-MRA, and 64 patients (93%) would repeat DSA if they needed another vascular examination. Forty-one patients preferred WB-MRA (60%), 12 patients preferred DSA (17%), and 16 patients had no preference (23%). Patient preference of WB-MRA over DSA was statistically significant (P< 0.001).
  
  
  CONCLUSIONS
  Patient acceptance of WB-MRA is superior to that of DSA in patients with PAD, with the majority of patients preferring WB-MRA.
authors.affiliation: Department of Radiology, Copenhagen University Hospital Herlev, Herlev Ringvej, Denmark. yujwni01@heh.regionh.dk
authors.forename: Yousef Wirenfeldt
authors.initials: YW
authors.lastname: Nielsen
authors.forename: Jonas P
authors.initials: JP
authors.lastname: Eiberg
authors.forename: Vibeke B
authors.initials: VB
authors.lastname: Løgager
authors.forename: Sven
authors.initials: S
authors.lastname: Just
authors.forename: Torben V
authors.initials: TV
authors.lastname: Schroeder
authors.forename: Henrik S
authors.initials: HS
authors.lastname: Thomsen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000379:methods; D050197:Atherosclerosis / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D007479:Iopamidol / Q000031:analogs & derivatives; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D051598:Whole Body Imaging / Q000379:methods*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C057937:iomeprol; D008536:Meglumine; D007479:Iopamidol; C072417:gadoterate meglumine