title: BCR-ABL1 tyrosine kinase activity at diagnosis, as determined via the pCrkL/CrkL ratio, is predictive of clinical outcome in chronic myeloid leukaemia.
authors.forename: Claire M
authors.initials: CM
authors.lastname: Lucas
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Harris
authors.forename: Athina
authors.initials: A
authors.lastname: Giannoudis
authors.forename: Katy
authors.initials: K
authors.lastname: Knight
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Watmough
authors.forename: Richard E
authors.initials: RE
authors.lastname: Clark
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000097:blood*; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood; D009687:Nuclear Proteins / Q000097:blood*; D010879:Piperazines / Q000627:therapeutic use; D011379:Prognosis; D011446:Prospective Studies; D011743:Pyrimidines / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D000970:Antineoplastic Agents; D001549:Benzamides; D014408:Biomarkers, Tumor; C082869:CRKL protein; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate