A woman with multiple autoimmune diseases: pathologic correlations and complications.
A very uncommon case report of a young woman suffering from multiple autoimmune-dysreactive disorders (including thyroiditis, myasthenia gravis, Crohn's disease, and erythema nodosum), while undergoing steroideal therapy, was complicated by a severe upper urinary tract infection. The pathogenetic and clinical association between the different autoimmune-dysreactive complications deserves discussion, as well as the eventual supporting role of the immunosuppressive treatment, which might contribute significantly to these risk factors. Clinicians who are engaged in the management of these patients should be aware that multiple, concurrent or subsequent disorders may occur in these subjects, and also severe infectious complications may be of relevant concern.
Manfredi
Roberto
R
Department of Clinical and Experimental Medicine, Division of Infectious Diseases, Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy. roberto.manfredi@unibo.it
D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans