[Study on the influence of the configuration of porcine aortic root on the stentless valve design].
OBJECTIVE
To provide the reference for the stentless aortic valve design with the study of the inner configuration of porcine aortic root.


METHODS
The orifice areas of porcine aortic root at 4 levels (OA1 to 4), the average area of leaflets (Sa), the area analogue of leaflets (AA, AA = 1/2PH), the average area analogue of leaflets (AAa), the value PH of the left, right, non coronary leaflets (PHl, PHr, PHn) and the sums of PHs of the left and non-coronary leaflets (PHln) in the fresh and glutaraldehyde and epichlorohydrin-treated porcine aortic valves (20 respectively) were measured and calculated. The linear correlation and regression analysis by SPSS 12.0 was used to analyze the correlation between Sa and AAa, OA and Sa, OA and AAa, PHl, PHr and PHn, PHln and PHr in both groups.


RESULTS
The coefficient correlation between Sa and AAa in fresh and treated groups were 0.886 and 0.872 respectively (P < 0.05). The coefficient correlation between OA1 to 4 and AAa were 0.810, 0.851, 0.900, and 0.815 respectively in fresh group (P < 0.05), and were 0.852, 0.888, 0.836, and 0.817 respectively in treated group (P < 0.05). This showed that the degree of correlation between the average area analogue of leaflets and the average area of leaflets, the orifice areas of aortic root were relatively large. Additionally, the equation of linear regression existed between PHln and PHr in treated group as follows: PHr = -1.665 + 0.688 PHln (r = 0.907, P < 0.05), thereby PHr could be predicted by PHln.


CONCLUSIONS
The value of PH of leaflets could represent the spatial configuration of the aortic root, which provided a referred index for the stentless bioprostheses design.
Wu
Fan
F
Department of Cardiovascular Surgery, Xijing Hospital, Forth Military Medical University, Xi'an 710032, China.
Wei
Xu-feng
XF
Yi
Ding-hua
DH
Tan
Hong-mei
HM
Xu
Shu
S
Liu
Wei-yong
WY
D000818:Animals; D001021:Aortic Valve; D001705:Bioprosthesis; D006350:Heart Valve Prosthesis; D006863:Hydrogen-Ion Concentration; D011474:Prosthesis Design; D015607:Stents; D013552:Swine; D023822:Tissue Engineering