Histopathological effects of cypermethrin on gill, liver and kidney of fresh water fish Clarias gariepinus (Burchell, 1822), and recovery after exposure.
Gill, liver and kidney of Clarias gariepinus were examined histologically after exposure to sublethal concentrations (10.05, 20.10 and 30.15 microg/L) of cypermethrin for 10 days. Histological recovery was also studied by maintaining the pesticide-exposed fish in a fresh water system for an additional 10 days. Epithelial hypertrophy and hyperplasia, epithelial lifting, oedema, fusion of secondary lamellae, necrosis and desquamation were histopathological changes in the gills of fish exposed to cypermethrin. Hepatic lesions in the liver tissues of fish were characterized by cloudy swelling of hepatocytes, lipoid vacuoles, pycnotic nuclei and focal necrosis. Epithelial hypertrophy, narrowing of the tubular lumen, atrophy of the glomerulus, broader Bowman's capsule, necrosis in the epithelial cells and pycnosis in the hematopoietic tissue were observed in kidney tissues of fish. These lesions grew with increasing concentration. Although some of the changes were reversible, the rest were less pronounced after a recovery period; a period of 10 days was not long enough for complete recovery.
Velmurugan
Babu
B
Environmental Science and Biotechnology Research Unit, Department of Zoology, Loyola College, Chennai - 600 034, Tamil Nadu, India.
Mathews
Thresia
T
Cengiz
Elif Ipek
EI
D000818:Animals; D002397:Catfishes; D005618:Fresh Water; D005880:Gills / Q000187:drug effects* / Q000473:pathology; D006651:Histocytochemistry; D007306:Insecticides / Q000009:adverse effects*; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D009336:Necrosis; D011722:Pyrethrins / Q000009:adverse effects*; D014874:Water Pollutants, Chemical / Q000009:adverse effects*
D007306:Insecticides; D011722:Pyrethrins; D014874:Water Pollutants, Chemical; C017160:cypermethrin