title: Functional relaxation as complementary therapy in irritable bowel syndrome: a randomized, controlled clinical trial.
abstract: OBJECTIVE
  Irritable bowel syndrome (IBS) is a frequently disabling and almost invariably distressing disease with a high overall prevalence. Numerous trials identified the importance of psychogenic and emotional etiological factors, and this is obvious in clinical practice. Although relaxation techniques are frequently recommended, there is still a lack of evidence for their efficacy in the management of IBS. This study therefore aims to determine the efficacy of functional relaxation (FR) in IBS.
  
  
  METHODS
  The subjects were 80 patients with IBS.
  
  
  METHODS
  Participants were randomly allocated either to FR or to enhanced medical care (EMC: treatment as usual plus two counseling interviews) as control intervention with 2 weekly sessions over the 5-week trial each. Thirty-nine (39) patients completed FR and 39 received EMC.
  
  
  METHODS
  An impairment-severity score (IS) was employed as the primary outcome parameter with assessment at baseline, after treatment, and again after 3-month follow-up.
  
  
  RESULTS
  FR was significantly superior to EMC with a standardized effect size of 0.85. The achieved effects through FR remained stable in terms of psychic and bodily impairment after 3-month follow-up.
  
  
  CONCLUSIONS
  The results of our trial suggest a positive effect of FR training on subjective functional impairment in the IS, if provided in addition to treatment as usual (TAU). There appears to be a clinically relevant long-term benefit of FR as a nonpharmacological and complementary therapy approach in IBS.
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany. lahmann@tum.de
authors.forename: Claas
authors.initials: C
authors.lastname: Lahmann
authors.forename: Frank
authors.initials: F
authors.lastname: Röhricht
authors.forename: Nina
authors.initials: N
authors.lastname: Sauer
authors.forename: Michael
authors.initials: M
authors.lastname: Noll-Hussong
authors.forename: Joram
authors.initials: J
authors.lastname: Ronel
authors.forename: Gerhard
authors.initials: G
authors.lastname: Henrich
authors.forename: Angela
authors.initials: A
authors.lastname: von Arnim
authors.forename: Thomas
authors.initials: T
authors.lastname: Loew
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000145:classification / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012064:Relaxation Therapy; D012720:Severity of Illness Index; D016037:Single-Blind Method; D016896:Treatment Outcome