[On the susceptibility of AmpC-producing bacteria to third-generation cephalosporins].
Enterobacteriaceae with mixed inducible and constitutive production of AmpC beta-lactamases are of growing clinical significance. Strains showing single colonies inside the zone of inhibition around disks with third-generation cephalosporins should be carefully considered for clinical use despite the fact that, according to the current EUCAST "breakpoints", they remain susceptible or intermediate-susceptible.
Jirsa
Roman
R
Department of Clinical Microbiology, Regional Hospital Mladá Boleslav, Mladá Boleslav, Czech Republic. roman.jirsa@onmb.cz
Kolár
Milan
M
D001426:Bacterial Proteins / Q000096:biosynthesis*; D002511:Cephalosporins / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000096:biosynthesis*
D001426:Bacterial Proteins; D002511:Cephalosporins; C048795:AmpC beta-lactamases; D001618:beta-Lactamases