title: Trailing or paradoxical growth of Candida albicans when exposed to caspofungin is not associated with microsatellite genotypes.
abstract: Multilocus microsatellite polymorphisms in 27 clinical Candida albicans isolates were found to be clearly unrelated to in vitro paradoxical growth or trailing effect with caspofungin. These findings suggest that such in vitro phenotypes are either gained or lost too rapidly to be predicted by more stable genomic markers.
authors.affiliation: Laboratoire de Biologie Moléculaire Parasitaire et Fongique, Faculté de Médecine de Sfax, Sfax, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Khlif
authors.forename: Hervé
authors.initials: H
authors.lastname: Bogreau
authors.forename: Annie
authors.initials: A
authors.lastname: Michel-Nguyen
authors.forename: Ali
authors.initials: A
authors.lastname: Ayadi
authors.forename: Stéphane
authors.initials: S
authors.lastname: Ranque
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development*; D002177:Candidiasis / Q000382:microbiology; D000077336:Caspofungin; D054714:Echinocandins / Q000494:pharmacology*; D005838:Genotype; D006801:Humans; D055666:Lipopeptides; D008826:Microbial Sensitivity Tests; D018895:Microsatellite Repeats / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077336:Caspofungin