Rapid vacuolar sequestration: the horseweed glyphosate resistance mechanism.
BACKGROUND
Glyphosate-resistant (GR) weed species are now found with increasing frequency and threaten the critically important glyphosate weed-management system [corrected].


RESULTS
The reported (31)P NMR experiments on glyphosate-sensitive (S) and glyphosate-resistant (R) horseweed, Conyza canadensis (L.) Cronq., show significantly more accumulation of glyphosate within the R biotype vacuole.


CONCLUSIONS
Selective sequestration of glyphosate into the vacuole confers the observed horseweed resistance to glyphosate. This observation represents the first clear evidence for the glyphosate resistance mechanism in C. canadensis.
Ge
Xia
X
Department of Chemistry, Washington University, St Louis, MO 63130, USA.
d'Avignon
D André
DA
Ackerman
Joseph J H
JJ
Sammons
R Douglas
RD
D035401:Conyza / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism*; D005998:Glycine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D053209:Herbicide Resistance; D006540:Herbicides / Q000378:metabolism* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000166:cytology / Q000187:drug effects / Q000378:metabolism / Q000502:physiology; D013997:Time Factors; D014617:Vacuoles / Q000378:metabolism*; D000097797:Glyphosate
D005998:Glycine; D006540:Herbicides; D000097797:Glyphosate