A synthesis of oligomeric alpha-hydroxy phenylphosphinates and a study of the conformational preferences of the dimers.
A general method for the synthesis of a novel class of oligomers, comprising alpha-hydroxy phenylphosphinic acid building blocks, is reported. A series of dimeric alpha-hydroxy phenylphosphinates are analyzed by a combination of NMR spectroscopy, X-ray crystallography and computational methods.
Afarinkia
Kamyar
K
Institute of Cancer Therapeutics, Thumbling Hill Street, Bradford, UK BD7 1DP. k.afarinkia@bradford.ac.uk
Royappa
Martin
M
Scowen
Ian J
IJ
Steed
Jonathan W
JW
Yu
Hiu-Wan
HW
D002244:Carbon / Q000737:chemistry; D019281:Dimerization; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010758:Phosphorus / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*; D017510:Protein Folding; D013237:Stereoisomerism; D013816:Thermodynamics
D009943:Organophosphorus Compounds; D011108:Polymers; D010758:Phosphorus; D002244:Carbon; C023604:phenylphosphonic acid