Lbx1 expression and frog limb development.
In order to identify prospective limb muscle cells in a frog, we cloned Lbx1 from the direct developing frog Eleutherodactylus coqui. Like in embryos of the frog Xenopus laevis but unlike in other vertebrates, EcLbx1 is expressed in all trunk somites. Like in embryos of chick, mouse, and zebrafish, cells expressing EcLbx1 are then found in limb buds, consistent with migration of those cells from somites. EcLbx1 is also expressed in the dorsal spinal cord as in other vertebrates.
Sabo
Michelle C
MC
Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Nath
Kimberly
K
Elinson
Richard P
RP
D000595:Amino Acid Sequence; D000818:Animals; D001001:Anura / Q000033:anatomy & histology / Q000196:embryology*; D003001:Cloning, Molecular; D017931:DNA Primers / Q000235:genetics; D004625:Embryo, Nonmammalian / Q000033:anatomy & histology; D005121:Extremities / Q000033:anatomy & histology / Q000196:embryology*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D006254:Hawaii; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D010802:Phylogeny; D011647:Puerto Rico; D019170:Somites / Q000378:metabolism*; D013116:Spinal Cord / Q000378:metabolism
D017931:DNA Primers; D018398:Homeodomain Proteins