title: The clinical presentations of ectopic biliary drainage into duodenal bulbus and stomach with a thorough review of the current literature.
abstract: BACKGROUND
  Ectopic biliary drainage is a rare congenital anomaly on which we have scarce data in the current literature.
  
  
  METHODS
  The data were collected from the records of 400 endoscopic retrograde cholangio-pancreatography (ERCP). In this report, we present 10 cases (male/female: 9/1, mean age 54 years, range 38-74) with ectopic biliary openings into the duodenum and/or stomach diagnosed by endoscopic retrograde cholangio-pancreatography (ERCP).
  
  
  RESULTS
  In our series, the frequency of ectopic biliary drainage is 2% (10 out of 400 ERCPs). Recurrent attacks of cholangitis and complicated ulcer formation in the distal stomach and bulbar duodenum were the most common signs in the present series. The sites of ectopic biliary drainage were the stomach in 1 case, the duodenum bulbus in 7 cases and the postbulbar duodenum in 2 cases. Bulbar ulcer, deformed pylorus and bulbus were present in 7 cases, apical bulbar stricture in 2, gastric ulcer in 1, pyloroplasty and/or gastroenterostomy in 3 cases. One case had had previous bleeding episode. Some of them had undergone previous surgeries for gall-stone disease (cholecystectomy in 5 cases, bile duct operation in 3 cases) and ulcer complications (pyloroplasty/gastroenterostomy in 3 cases). ERCP revealed dilatation of the biliary tree and hook shaped distal choledochus in all cases, choledocholithiasis in 7 and Mirizzi syndrome in 1. Endoscopic balloon dilatations for gastric outlet obstruction, extraction of bile stones after balloon dilating the ectopic site, surgery for difficult cases with large bile duct stones or with gastric outlet obstruction were preferred methods in this series of patients.
  
  
  CONCLUSIONS
  With this report, we have to remind that ectopic biliary drainage must be considered in the differential diagnosis when the clinician faces cases with gastric outlet obstruction due to peptic ulcer formation accompanied by cholangitis/cholestasis.
authors.affiliation: Department of Internal Medicine, Süleyman Demirel University School of Medicine, Isparta, 32040 Turkey.
authors.forename: Ulku
authors.initials: U
authors.lastname: Saritas
authors.forename: Altug
authors.initials: A
authors.lastname: Senol
authors.forename: Yucel
authors.initials: Y
authors.lastname: Ustundag
mesh_terms: D015746:Abdominal Pain / Q000453:epidemiology; D000328:Adult; D000368:Aged; D015984:Causality; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000706:statistics & numerical data*; D002761:Cholangitis / Q000453:epidemiology; D042883:Choledocholithiasis / Q000453:epidemiology; D003135:Common Bile Duct / Q000002:abnormalities*; D015897:Comorbidity; D003937:Diagnosis, Differential; D004065:Digestive System Abnormalities / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D004108:Dilatation, Pathologic / Q000175:diagnosis; D004381:Duodenal Ulcer / Q000453:epidemiology; D004386:Duodenum / Q000002:abnormalities*; D005260:Female; D005334:Fever / Q000453:epidemiology; D017219:Gastric Outlet Obstruction / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007565:Jaundice / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000453:epidemiology; D011708:Pylorus / Q000002:abnormalities*; D012008:Recurrence; D012189:Retrospective Studies