Antenatal diagnostic problem of congenital rubella.
We present a preterm neonate who developed congenital rubella syndrome in a mother who had rubella at 5 months of gestation. An amniocentesis was done in the mother at that time but amniotic fluid rubella PCR was negative. Thus, inspite of prenatal screening, one cannot definitely conclude absence of perinatal transmission of rubella.
Shah
Ira
I
Department of Pediatric Hepatobiliary Clinic, B. J. Wadia Hospital for Children, Parel, Mumbai, India. irashah@pediatriconcall.com
Bhatnagar
Sushmita
S
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000821:virology; D004200:Diseases in Twins / Q000175:diagnosis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008297:Male; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D011296:Prenatal Diagnosis; D012409:Rubella / Q000175:diagnosis; D012410:Rubella Syndrome, Congenital / Q000175:diagnosis*