title: A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme.
abstract: A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT and MS spectra). The alcoholic and aqueous extracts of the leaves of C. inerme showed significant antinociceptive activity in analgaesiometer tests.
authors.affiliation: Department of Chemistry, Aligarh Muslim University, Aligarh-202002, UP, India. mehtab_organic@rediffmail.com
authors.forename: Mehtab
authors.initials: M
authors.lastname: Parveen
authors.forename: Zakia
authors.initials: Z
authors.lastname: Khanam
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ali
authors.forename: Syed Ziaur
authors.initials: SZ
authors.lastname: Rahman
mesh_terms: D032409:Clerodendrum / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D014315:Triterpenes / Q000302:isolation & purification*
chemical_list: D010936:Plant Extracts; D014315:Triterpenes