[Simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure].
OBJECTIVE
To review the clinical experiences concerning simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure.


METHODS
This study involved 8 cases of simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure. There were 5 male and 3 female patients, aged from 41 to 67 years old with a mean of 52.8 years old. Six cases transplanted kidney after liver with orthotopic liver transplantation, and 2 cases transplanted liver after kidney with piggy-back liver transplantation. The acute rejections, complications, liver function, kidney functions, and survival rates of patient/liver/kidney were recorded.


RESULTS
Within the follow-up of 28 to 65 months, all 8 patients are still alive with normal liver and kidney functions: 2 living more than 5 years, 2 living more than 4 years and 4 living more than 2 years. 2 cases of pleural effusion and 1 case of pneumonia were complications after operation, which had been cured successfully. No acute rejection of allograft was observed.


CONCLUSIONS
Simultaneous liver-kidney transplantation is a safe and effective treatment for polycystic kidney and hepatic disease with kidney and liver failure.
Yu
Li-xin
LX
Center of Organ Transplantation, Nan Fang Hospital, Southern Medical University, Guangzhou 510515, China. mypangpang_8@163.com
Wang
Yan-bin
YB
Xu
Jian
J
Deng
Wen-feng
WF
Fu
Shao-jie
SJ
Du
Chuan-fu
CF
Wang
Yi-bin
YB
Miao
Yun
Y
Ye
Gui-rong
GR
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D008107:Liver Diseases / Q000150:complications / Q000601:surgery; D017093:Liver Failure / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D007690:Polycystic Kidney Diseases / Q000150:complications / Q000601:surgery*; D051437:Renal Insufficiency / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome