title: Tumor self-seeding: bidirectional flow of tumor cells.
abstract: Circulating tumor cells are responsible for seeding metastatic growth at distant sites. Kim et al. (2009) now discover that circulating tumor cells can reinfiltrate tumors at their primary organs and promote tumor progression.
authors.affiliation: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Cheuk T
authors.initials: CT
authors.lastname: Leung
authors.forename: Joan S
authors.initials: JS
authors.lastname: Brugge
mesh_terms: D000818:Animals; D018450:Disease Progression; D006801:Humans; D009366:Neoplasm Seeding; D009369:Neoplasms / Q000473:pathology* / Q000503:physiopathology; D009360:Neoplastic Cells, Circulating / Q000473:pathology*