Underlying purinergic signaling contributes to T lymphocyte activation in tissue repair. Focus on "shockwaves increase the T-cell proliferation and IL-2 expression through ATP release, P2X7 receptors, and FAK activation".
Schwiebert
Erik M
EM
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D049109:Cell Proliferation / Q000528:radiation effects*; D002470:Cell Survival; D004789:Enzyme Activation; D051417:Focal Adhesion Kinase 1 / Q000378:metabolism*; D019220:High-Energy Shock Waves; D006801:Humans; D007376:Interleukin-2 / Q000378:metabolism*; D008213:Lymphocyte Activation / Q000528:radiation effects; D010766:Phosphorylation; D018048:Receptors, Purinergic P2 / Q000378:metabolism*; D058486:Receptors, Purinergic P2X7; D012038:Regeneration / Q000528:radiation effects; D015398:Signal Transduction / Q000528:radiation effects*; D013601:T-Lymphocytes / Q000201:enzymology / Q000276:immunology / Q000528:radiation effects*; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism
C508594:IL2 protein, human; D007376:Interleukin-2; C546468:P2RX7 protein, human; D018048:Receptors, Purinergic P2; D058486:Receptors, Purinergic P2X7; D000255:Adenosine Triphosphate; D051417:Focal Adhesion Kinase 1; C496050:PTK2 protein, human; D048051:p38 Mitogen-Activated Protein Kinases