title: Studies on some feed additives and materials giving partial protection against the suppressive effect of ochratoxin A on egg production of laying hens.
abstract: The protective effects of various feed supplements against the harmful effect of ochratoxin A on egg production and sexual maturation of two-weeks old Plymouth Rock female chicks designed for laying hens were studied. A significant protective effect of the feed additives or materials: water extract of artichoke (WEA), sesame seed (SS), Roxazyme-G (RG) and l-beta phenylalanine (PHE) against the suppressive effect of ochratoxin A (OTA) on egg production of laying hens was found. A similar protection was also seen on the toxic effect of OTA on various internal organs of the same hens. A significant protection was found against the decrease of the weight or the quantity of eggs as well as against the delay of the beginning of the laying period of chicks, both of which were provoked by ochratoxin A. These protective effects were strongest in chicks treated with SS or WEA, but were slightest in chicks treated with l-beta PHE.
authors.affiliation: Department of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000 Stara Zagora, Bulgaria. stoev@uni-sz.bg
authors.forename: Stoycho D
authors.initials: SD
authors.lastname: Stoev
mesh_terms: D000821:Animal Feed; D000818:Animals; D000931:Antidotes / Q000494:pharmacology; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D004531:Eggs; D005260:Female; D005503:Food Additives / Q000008:administration & dosage*; D006799:Housing, Animal / Q000592:standards; D009183:Mycotoxins / Q000037:antagonists & inhibitors / Q000633:toxicity; D009793:Ochratoxins / Q000037:antagonists & inhibitors / Q000633:toxicity*; D010058:Oviposition / Q000187:drug effects*; D010649:Phenylalanine / Q000494:pharmacology; D012639:Seeds; D031685:Sesamum; D013047:Specific Pathogen-Free Organisms; D015430:Weight Gain / Q000187:drug effects
chemical_list: D000931:Antidotes; D005503:Food Additives; D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A; D010649:Phenylalanine