Should all embryos from day 1 rescue intracytoplasmic sperm injection be transferred during frozen-thawed cycles?
A retrospective analysis of a 5-year rescue intracytoplasmic sperm injection (ICSI) experience performed in 17 cases of complete IVF fertilization failure showed that the ongoing pregnancy rate per embryo transfer (ET) is much higher in a subsequent frozen-thawed cycles (40%, 2/5) than following a fresh ET (6.7%, 1/15). These results suggest that cryopreservation of all embryos, subsequently used in frozen-thawed cycles, might improve rescue ICSI outcome throughout a better synchronization of the embryo development with the endometrium.
Sermondade
Nathalie
N
Service d'Histologie-Embryologie-Cytogénétique-Biologie de la Reproduction-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique-Hôpitaux de Paris, Bondy, France.
Hugues
Jean-Noël
JN
Cedrin-Durnerin
Isabelle
I
Poncelet
Christophe
C
Benzacken
Brigitte
B
Lévy
Rachel
R
Sifer
Christophe
C
D000328:Adult; D015925:Cryopreservation; D004624:Embryo Transfer / Q000379:methods*; D004622:Embryo, Mammalian; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D005615:Freezing; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors; D017211:Treatment Failure