Synthesis of chromones via palladium-catalyzed ligand-free cyclocarbonylation of o-iodophenols with terminal acetylenes in phosphonium salt ionic liquids.
The highly efficient and selective palladium-catalyzed ligand-free cyclocarbonylation reaction of o-iodophenols with terminal acetylenes and CO in the phosphonium salt ionic liquid, C(14)H(29)(C(6)H(13))(3)P(+)Br(-), affords diversified chromones in good to excellent yields under atmospheric CO pressure. The ionic liquid, as the reaction medium, enhances the efficiency of the cyclocarbonylation reaction.
Yang
Qian
Q
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada.
Alper
Howard
H
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D052578:Ionic Liquids; D008024:Ligands; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012492:Salts; D013055:Spectrophotometry, Infrared
D000480:Alkynes; D002867:Chromones; D052578:Ionic Liquids; D008024:Ligands; D009943:Organophosphorus Compounds; D012492:Salts; D010165:Palladium