title: Galaxy: a web-based genome analysis tool for experimentalists.
abstract: High-throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus, making sense of high-throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is distributed both as a publicly available Web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual laboratories. Either way, it allows experimentalists without informatics or programming expertise to perform complex large-scale analysis with just a Web browser.
authors.affiliation: The Huck Institutes for the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Blankenberg
authors.forename: Gregory
authors.initials: G
authors.lastname: Von Kuster
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Coraor
authors.forename: Guruprasad
authors.initials: G
authors.lastname: Ananda
authors.forename: Ross
authors.initials: R
authors.lastname: Lazarus
authors.forename: Mary
authors.initials: M
authors.lastname: Mangan
authors.forename: Anton
authors.initials: A
authors.lastname: Nekrutenko
authors.forename: James
authors.initials: J
authors.lastname: Taylor
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods*; D005821:Genetic Techniques; D016678:Genome; D006801:Humans; D020407:Internet; D012985:Software Design