title: [Ultrafiltration process of model system of Huanglian Jiedu decoction].
abstract: OBJECTIVE
  The UF process of model systerm of Huanglian Jiedu decoction is researched in the study to lay a foundation for the exploring of the substance foudation of membrane fouling, and for the the optimal design of membrane technology in the production of Chinese drugs preparation.
  
  
  METHODS
  Using the membrane flux, fouling degree of membrane, preserving degree and adsorption capacity of effective materials as guide line, trying to find out the influence of macromolecule materials on small molecules in Huanglian Jiedu decoction.
  
  
  RESULTS
  The two small molecules berberine and gardenoside in Huanglian Jiedu decoction have high permeation rate. But for the reasons of interaction of macromolecule, the permeation rate of small molecules reduced greatly, membrane fouling and membrane flux declined intensify.
  
  
  CONCLUSIONS
  Starch and pectin are the two main macromolecule materials in Huanglian Jiedu decoction which cause membrane fouling and flux falling.
authors.affiliation: School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210029, China. dongjie790212@yahoo.com.cn
authors.forename: Jie
authors.initials: J
authors.lastname: Dong
authors.forename: Huaxu
authors.initials: H
authors.lastname: Zhu
authors.forename: Liwei
authors.initials: L
authors.lastname: Guo
mesh_terms: D000327:Adsorption; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008567:Membranes, Artificial; D014462:Ultrafiltration / Q000295:instrumentation / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D008567:Membranes, Artificial; C494417:huanglian