title: Glucose influence on the production of T-2 toxin by Fusarium sporotrichioides.
abstract: Toxigenic isolate of Fusarium sporotrichioides was tested for the T-2 toxin production on PDA plates during 10 days under various glucose concentrations. T-2 toxin was determined by LC-MS and confirmed with LC-MS/MS. This analytical method has been applied, for the first time, to an extensive study of T-2 accumulation. Results showed that the production of this mycotoxin is directly correlated to the concentration of glucose present in the medium. Concentrations of T-2 toxin produced by the strain of F. sporotrichioides ranged from 0 to 1.45 mg/kg. The better T-2 production was evidenced in the fermentation operated with 20% of glucose.
authors.affiliation: Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of València, València, Spain. jesus.blesa@uv.es
authors.forename: J
authors.initials: J
authors.lastname: Blesa
authors.forename: G
authors.initials: G
authors.lastname: Meca
authors.forename: J
authors.initials: J
authors.lastname: Rubert
authors.forename: J M
authors.initials: JM
authors.lastname: Soriano
authors.forename: A
authors.initials: A
authors.lastname: Ritieni
authors.forename: J
authors.initials: J
authors.lastname: Mañes
mesh_terms: D002851:Chromatography, High Pressure Liquid; D017077:Culture Media, Conditioned / Q000737:chemistry; D005670:Fusarium / Q000187:drug effects* / Q000378:metabolism; D005947:Glucose / Q000494:pharmacology*; D013605:T-2 Toxin / Q000032:analysis / Q000096:biosynthesis*; D053719:Tandem Mass Spectrometry
chemical_list: D017077:Culture Media, Conditioned; D013605:T-2 Toxin; D005947:Glucose