title: Method for the determination of organophosphorus and pyrethroid pesticides in food via gas chromatography with electron-capture detection.
abstract: We have developed a rapid, high-throughput, accurate, multiresidue method for the analysis of selected organophosphorus and pyrethroid pesticides in a variety of food samples suitable for use in public health and epidemiologic investigations of high-use pesticides using modifications of existing methods. The procedure involves a pesticide extraction from the food sample with acetonitrile followed by a salting-out with NaCl and cleanup of the extract with a multilayer solid-phase extraction cartridge composed of a Supelclean ENVI-CARB-II top layer and a primary-secondary amine bottom layer separated by a polyethylene frit. To evaluate the method, we performed fortification studies at 50, 100, and 200 ng/g for 3 organophosphorus and 4 pyrethroid pesticides in 16 different foods. Instrumental analysis was carried out by capillary gas chromatography with electron-capture detection (GC-ECD). Confirmatory analysis was performed by GC coupled with mass spectrometry (MS) in the selected-ion monitoring (SIM) mode. Average recoveries for each fortification level ranged from 49 to 146% with 80% of recoveries between 80 and 120%.
authors.affiliation: Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Ronald E
authors.initials: RE
authors.lastname: Hunter
authors.forename: Anne M
authors.initials: AM
authors.lastname: Riederer
authors.forename: P Barry
authors.initials: PB
authors.lastname: Ryan
mesh_terms: D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D009943:Organophosphorus Compounds / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D011722:Pyrethrins / Q000032:analysis*
chemical_list: D009943:Organophosphorus Compounds; D010573:Pesticide Residues; D011722:Pyrethrins