title: EEG topography-specific BOLD changes: a continuous EEG-fMRI study in a patient with focal epilepsy.
abstract: Blood oxygenation level dependent (BOLD) response related to interictal activity was evaluated in a patient with post-traumatic focal epilepsy at repeated continuous electroencephalogram (EEG)-functional magnetic resonance imaging examinations. Lateralized interictal EEG activity induced a main cluster of activation co-localized with the anatomical lesion. Spreading of EEG interictal activity to both frontal lobes evoked bilateral clusters of activation indicating that topography of BOLD response might depend on the spatial distribution of epileptiform activity.
authors.affiliation: Department of Neuroscience University of Pisa, 56100 Pisa, Italy. mircocosottini@libero.it
authors.forename: Mirco
authors.initials: M
authors.lastname: Cosottini
authors.forename: Ilaria
authors.initials: I
authors.lastname: Pesaresi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Maritato
authors.forename: Gina
authors.initials: G
authors.lastname: Belmonte
authors.forename: Arianna
authors.initials: A
authors.lastname: Taddei
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Sartucci
authors.forename: Mario
authors.initials: M
authors.lastname: Mascalchi
authors.forename: Luigi
authors.initials: L
authors.lastname: Murri
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male