[Analysis of polio antibody levels in healthy population in Beijing in 2007].
OBJECTIVE
To investigate the poliomyelitis antibody level in healthy people in Beijing.


METHODS
10 age groups (0, 1 to 4, 5 to 9, 10 to 14, 15 to 19, 20 to 24, 25 to 29, 30 to 34, 35 to 39, and > or = 40) were sampled by the Multi-stage stratified sampling method in 7 districts in Beijing, and 1552 sera from healthy population were collected. The poliomyelitis antibody was determined with microcell neutralization method.


RESULTS
The neutralized antibody-positive rate for polio I, II, III were 97.04%, 97.29% and 91.04% respectively, the geometric mean titers (GMT) were 1:70.05, 1:54.60, and 1:31.83 respectively. A trend of decreasing was observed in the GMTs with increasing age and years after immunization. There were no significant differences in antibody levels between different gender, residents or regions. The results of multiple-factors analysis showed that the GMTs were significantly associated with age and the years after immunization.


CONCLUSIONS
A stable immunization barrier has been established in healthy population in Beijing.
Li
Xiao-mei
XM
Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
Zhang
He-run
HR
Wang
Yu-mei
YM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006304:Health Status; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011051:Poliomyelitis / Q000097:blood* / Q000276:immunology; D017955:Poliovirus / Q000276:immunology; D011159:Population Surveillance; D055815:Young Adult
D000914:Antibodies, Viral