title: Herpetic geometric glossitis: acyclovir resistant case in a patient with acute myelogenous leukemia.
abstract: Herpes simplex virus (HSV) infections in an immunocompromised host may be atypical in location and morphology. Lesions are more extensive and aggressive, slow healing or nonhealing and extremely painful. Intraoral lesions are ulcerative and may involve any intraoral, oropharyngeal, or esophageal site. Herpetic geometric glossitis is a recently described form of lingual HSV infection in an immunocompromised patient. It was described as ulcer on the dorsum of the tongue sensitive for acyclovir therapy. A patient is presented with acute myelogenous leukemia that developed herpetic geometric glossitis which was acyclovir resistant.
authors.affiliation: School of Dentistry, Paulista University, Goiânia/GO, Brazil.
authors.forename: Claudio Maranhao
authors.initials: CM
authors.lastname: Pereira
authors.forename: Carmino Antonio
authors.initials: CA
authors.lastname: Souza
authors.forename: Maria Elvira P
authors.initials: ME
authors.lastname: Correa
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D024882:Drug Resistance, Viral; D005928:Glossitis / Q000188:drug therapy* / Q000821:virology*; D006561:Herpes Simplex / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged; D014059:Tongue / Q000473:pathology; D017211:Treatment Failure
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir