title: Does MRI with oral contrast medium allow single-study depiction of inflammatory bowel disease enteritis and colitis?
abstract: OBJECTIVE
  To assess the feasibility and utility of magnetic resonance (MR) imaging of the bowel in concurrent small- and large-bowel evaluation for the presence of inflammatory bowel disease (IBD).
  
  
  METHODS
  Over a 5-year period, 62 MR examinations performed on 53 patients demonstrated evidence of IBD. Sixteen of these 53 (30.1%) patients had imaging findings of colonic disease and underwent 19 formal MR small bowel examinations. These were further evaluated for bowel distention and image quality. The sensitivity and specificity of the technique compared with colonoscopy as the 'gold standard' was evaluated.
  
  
  RESULTS
  Simultaneous imaging of the colon is feasible at MR small bowel follow-through with moderate-to-excellent colonic visibility and colon distention obtained when the contrast medium is present in the colon at the time of image acquisition. MR imaging had a sensitivity of 80% (0.56-0.93), specificity of 100% (0.77-1.00), positive predictive value (PPV) of 1 and a negative predictive value (NPV) of 0.8 for the identification of colitis (based on available concurrent correlation of 38/62 examinations with colonoscopy).
  
  
  CONCLUSIONS
  Small and large bowel MR imaging with orally consumed contrast medium represents a promising, feasible, non-invasive, non-radiating single mode of assessment of the entire gastrointestinal tract, performed at a single sitting.
authors.affiliation: Department of Radiology, University College Hospital, Galway, Ireland. carmelcronin2000@hotmail.com
authors.forename: Carmel G
authors.initials: CG
authors.lastname: Cronin
authors.forename: Derek G
authors.initials: DG
authors.lastname: Lohan
authors.forename: Ann Michelle
authors.initials: AM
authors.lastname: Browne
authors.forename: Clare
authors.initials: C
authors.lastname: Roche
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Murphy
mesh_terms: D000284:Administration, Oral; D003092:Colitis / Q000175:diagnosis*; D003113:Colonoscopy / Q000379:methods; D003287:Contrast Media; D004751:Enteritis / Q000175:diagnosis*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis*; D007420:Intestine, Large / Q000000981:diagnostic imaging / Q000473:pathology; D007421:Intestine, Small / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D011859:Radiography; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media