title: HuD stimulates translation via eIF4A.
abstract: In this issue of Molecular Cell, Fukao et al. (2009) report that HuD upregulates mRNA translation through direct interaction with eIF4A in the 5' cap-binding complex, revealing a posttranscriptional role for HuD in neuronal development and plasticity.
authors.affiliation: Department of Biochemistry and Molecular Biology, The University of Texas Medical School, Houston, 77030, USA.
authors.forename: Chyi-Ying A
authors.initials: CY
authors.lastname: Chen
authors.forename: Ann-Bin
authors.initials: AB
authors.lastname: Shyu
mesh_terms: D000818:Animals; D002460:Cell Line; D051959:ELAV Proteins / Q000235:genetics / Q000378:metabolism*; D000067779:ELAV-Like Protein 4; D039601:Eukaryotic Initiation Factor-4A / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
chemical_list: D051959:ELAV Proteins; D000067779:ELAV-Like Protein 4; C498010:ELAVL4 protein, human; D012333:RNA, Messenger; D039601:Eukaryotic Initiation Factor-4A