title: Do comorbidities influence objective and subjective recovery rates of nasal polyposis?
abstract: OBJECTIVE
  To investigate the clinical and laboratory outcomes both objectively and subjectively in nasal polyposis patients with or without comorbidity (CoM; asthma and allergy).
  
  
  METHODS
  Thirty-three nasal polyposis patients (13 women and 20 men) were included into the study. Their mean age was 39.23 +/- 9.13 years. CoM(+) and CoM(-) nasal polyposis patients were compared with each other. Evaluations contained endoscopic nasal examination, acoustic rhinometry, rhinomanometry, visual analog scale score of nasal blockage, olfactory function score, respiratory function test, skin prick tests, and paranasal sinus computed tomography.
  
  
  RESULTS
  Recovery was statistically significant in all observed evaluations for endoscopic and radiologic staging, nasal obstruction, and sense of smell compared with the first evaluation in all patients regardless of the subgroups. Although objective measurements of respiratory functions did not show any change, clinical improvement was detected in CoM(+) patients with a decrease of need to their antiasthmatic medical treatment.
  
  
  CONCLUSIONS
  Results of CoM(+) patients led to no statistical difference when compared with CoM(-) subgroup. When applying predefined nasal polyposis treatment protocol, the polyp patients with CoMs do not need close follow-up compared to the patients without CoMs.
authors.affiliation: Otorhinolaryngology Department, Medical Faculty, Inonu University, Malatya, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akarcay
authors.forename: Nur
authors.initials: N
authors.lastname: Ekici
authors.forename: Murat C
authors.initials: MC
authors.lastname: Miman
authors.forename: Yezdan
authors.initials: Y
authors.lastname: Firat
authors.forename: Tuba
authors.initials: T
authors.lastname: Bayindir
authors.forename: Erol
authors.initials: E
authors.lastname: Selimoglu
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications; D015897:Comorbidity; D004724:Endoscopy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D008297:Male; D015508:Nasal Obstruction / Q000209:etiology; D009298:Nasal Polyps / Q000150:complications / Q000601:surgery*; D011446:Prospective Studies; D012129:Respiratory Function Tests; D025363:Rhinomanometry; D012307:Risk Factors; D012882:Skin Tests; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome