title: Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): pattern changes from inflammation to prostate cancer.
abstract: OBJECTIVE
  To assess (1)H-magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa).
  
  
  METHODS
  Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa = Group D and HGPCa = Group E).
  
  
  RESULTS
  ANOVA analysis shows that inflammation (Group B) displays no significantly (p >.05) different choline and citrate levels when compared to HGPIN and LGPCa.
  
  
  CONCLUSIONS
  our results suggest the potential for these MR imaging techniques in the description of inflammatory and proliferative lesions inside the prostate gland.
authors.affiliation: Department of Urology, Sapienza University, Viale Policlinico 155, Rome, Italy. sciarra.md@libero.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sciarra
authors.forename: Valeria
authors.initials: V
authors.lastname: Panebianco
authors.forename: Mauro
authors.initials: M
authors.lastname: Ciccariello
authors.forename: Stefano
authors.initials: S
authors.lastname: Salciccia
authors.forename: Danilo
authors.initials: D
authors.lastname: Lisi
authors.forename: Marcello
authors.initials: M
authors.lastname: Osimani
authors.forename: Andrea
authors.initials: A
authors.lastname: Alfarone
authors.forename: Alessandro
authors.initials: A
authors.lastname: Gentilucci
authors.forename: Ulderico
authors.initials: U
authors.lastname: Parente
authors.forename: Roberto
authors.initials: R
authors.lastname: Passariello
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Gentile
mesh_terms: D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D011472:Prostatitis / Q000175:diagnosis* / Q000378:metabolism