Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines.
An efficient synthesis of 1-aryl-5-aryl(alkyl)-1,2-dihydro-3H-1,2,4-triazole-3-thiones via reaction between ammonium thiocyanate, acid chlorides, and arylhydrazines is described.
Yavari
Issa
I
Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran. yavarisa@modares.ac.ir
Shirgahi-Talari
Faezeh
F
Hossaini
Zinatossadat
Z
Sabbaghan
Maryam
M
Seyfi
Samereh
S
D000143:Acids / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D003500:Cyclization; D006834:Hydrazines / Q000737:chemistry*; D017879:Isothiocyanates / Q000737:chemistry; D008954:Models, Biological; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D013861:Thiocyanates / Q000737:chemistry*; D013871:Thiones / Q000138:chemical synthesis*; D014230:Triazoles / Q000737:chemistry
D000143:Acids; D002712:Chlorides; D006834:Hydrazines; D017879:Isothiocyanates; D000644:Quaternary Ammonium Compounds; D013861:Thiocyanates; D013871:Thiones; D014230:Triazoles; C045575:1,2,4-triazole; C026976:thiocyanic acid