title: Impact of obesity on gynecology.
abstract: Rising obesity rates around the world have had a profound impact on female reproductive health. Childhood obesity is associated with early onset of puberty, menstrual irregularities during adolescence and polycystic ovary syndrome. Women of reproductive age with high BMIs have a higher risk of ovulatory problems and tend to respond poorly to fertility treatment. Strategies for fertility control can also be complex since the efficacy and safety of hormonal contraceptives can be compromised by increased body weight. Obesity can aggravate symptoms of pelvic organ prolapse, stress urinary incontinence and increase the risk of endometrial polyps and symptomatic fibroids. Weight reduction enhances reproductive outcomes, diminishes symptoms of urinary incontinence and reduces morbidity following gynecological surgery. Sustained and substantial weight loss is difficult to achieve with the lifestyle and dietary measures that are currently available. A number of pharmacological treatment options are available, and there are emerging data on reproductive outcomes following surgical treatment for obesity.
authors.affiliation: Assisted Reproduction Unit, Aberdeen Maternity Hospital, Foresterhill, Aberdeen AB25 2ZD, UK. s.pandey@abdn.ac.uk
authors.forename: Shilpi
authors.initials: S
authors.lastname: Pandey
authors.forename: Siladitya
authors.initials: S
authors.lastname: Bhattacharya
mesh_terms: D019440:Anti-Obesity Agents / Q000627:therapeutic use; D005260:Female; D005831:Genital Diseases, Female / Q000209:etiology*; D006176:Gynecology; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D007889:Leiomyoma / Q000150:complications; D009765:Obesity / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D011247:Pregnancy; D011627:Puberty / Q000502:physiology; D014550:Urinary Incontinence, Stress / Q000209:etiology; D016387:Women's Health
chemical_list: D019440:Anti-Obesity Agents