A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme.
A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT and MS spectra). The alcoholic and aqueous extracts of the leaves of C. inerme showed significant antinociceptive activity in analgaesiometer tests.
Parveen
Mehtab
M
Department of Chemistry, Aligarh Muslim University, Aligarh-202002, UP, India. mehtab_organic@rediffmail.com
Khanam
Zakia
Z
Ali
Mohammad
M
Rahman
Syed Ziaur
SZ
D032409:Clerodendrum / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D014315:Triterpenes / Q000302:isolation & purification*
D010936:Plant Extracts; D014315:Triterpenes