title: NetPath: a public resource of curated signal transduction pathways.
abstract: We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.
authors.affiliation: Institute of Bioinformatics, International Tech Park, Bangalore 560066, India. kumaran@ibioinformatics.org
authors.forename: Kumaran
authors.initials: K
authors.lastname: Kandasamy
authors.forename: S Sujatha
authors.initials: SS
authors.lastname: Mohan
authors.forename: Rajesh
authors.initials: R
authors.lastname: Raju
authors.forename: Shivakumar
authors.initials: S
authors.lastname: Keerthikumar
authors.forename: Ghantasala S Sameer
authors.initials: GS
authors.lastname: Kumar
authors.forename: Abhilash K
authors.initials: AK
authors.lastname: Venugopal
authors.forename: Deepthi
authors.initials: D
authors.lastname: Telikicherla
authors.forename: J Daniel
authors.initials: JD
authors.lastname: Navarro
authors.forename: Suresh
authors.initials: S
authors.lastname: Mathivanan
authors.forename: Christian
authors.initials: C
authors.lastname: Pecquet
authors.forename: Sashi Kanth
authors.initials: SK
authors.lastname: Gollapudi
authors.forename: Sudhir Gopal
authors.initials: SG
authors.lastname: Tattikota
authors.forename: Shyam
authors.initials: S
authors.lastname: Mohan
authors.forename: Hariprasad
authors.initials: H
authors.lastname: Padhukasahasram
authors.forename: Yashwanth
authors.initials: Y
authors.lastname: Subbannayya
authors.forename: Renu
authors.initials: R
authors.lastname: Goel
authors.forename: Harrys K C
authors.initials: HK
authors.lastname: Jacob
authors.forename: Jun
authors.initials: J
authors.lastname: Zhong
authors.forename: Raja
authors.initials: R
authors.lastname: Sekhar
authors.forename: Vishalakshi
authors.initials: V
authors.lastname: Nanjappa
authors.forename: Lavanya
authors.initials: L
authors.lastname: Balakrishnan
authors.forename: Roopashree
authors.initials: R
authors.lastname: Subbaiah
authors.forename: Y L
authors.initials: YL
authors.lastname: Ramachandra
authors.forename: B Abdul
authors.initials: BA
authors.lastname: Rahiman
authors.forename: T S Keshava
authors.initials: TS
authors.lastname: Prasad
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Lin
authors.forename: Jon C D
authors.initials: JC
authors.lastname: Houtman
authors.forename: Stephen
authors.initials: S
authors.lastname: Desiderio
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Renauld
authors.forename: Stefan N
authors.initials: SN
authors.lastname: Constantinescu
authors.forename: Osamu
authors.initials: O
authors.lastname: Ohara
authors.forename: Toshio
authors.initials: T
authors.lastname: Hirano
authors.forename: Masato
authors.initials: M
authors.lastname: Kubo
authors.forename: Sujay
authors.initials: S
authors.lastname: Singh
authors.forename: Purvesh
authors.initials: P
authors.lastname: Khatri
authors.forename: Sorin
authors.initials: S
authors.lastname: Draghici
authors.forename: Gary D
authors.initials: GD
authors.lastname: Bader
authors.forename: Chris
authors.initials: C
authors.lastname: Sander
authors.forename: Warren J
authors.initials: WJ
authors.lastname: Leonard
authors.forename: Akhilesh
authors.initials: A
authors.lastname: Pandey
mesh_terms: D022126:Access to Information; D000818:Animals; D017209:Apoptosis; D001671:Biochemistry / Q000379:methods; D002465:Cell Movement; D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D007107:Immune System; D007376:Interleukin-2 / Q000378:metabolism; D008954:Models, Biological; D008957:Models, Genetic; D025941:Protein Interaction Mapping; D015398:Signal Transduction; D012984:Software; D014158:Transcription, Genetic
chemical_list: D007376:Interleukin-2