[Treatment experience of severe acute pancreatitis on 1033 cases.].
OBJECTIVE
To summary the treatment experience of severe acute pancreatitis (SAP).


METHODS
From January 1997 to March 2009, a total of 1033 patients suffered SAP were admitted with a mean APACHE II score 12.0 +/- 4.3. There were 622 males and 411 females, aged from 13 to 98 years old. All patients were cared by the multidisciplinary team with intensivist, endoscopists, gastroenterologists, radiologist, nephrologist and surgeons.Patients treated in SICU in the early phase of the disease. In these 1033 patients, 365 cases received mechanical ventilation, 218 with tracheotomy, 159 cases received high-volume continuous venovenous hemofiltration (CVVH), 179 received nasobiliary drainage, 513 were treated with early enteral nutrition. CT-guided percutaneous catheter drainge for peripancreatic fluid collection was pefromed for 477 times and 438 patients received surgical debridement for infected pancreatic necrosis.


RESULTS
In all these 1033 cases, 975 patients (94.4%) survived, and 38 patients died (3.7%). The mortality of patients who received surgical debridement for infected pancreatic necrosis was 7.1% (31/438).


CONCLUSIONS
The muti-discipline management of severe acute pancreatitis can remarkably improve the prognosis of patients.
Li
Wei-Qin
WQ
Research Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China.
Tong
Zhi-Hui
ZH
Quan
Zhu-Fu
ZF
Zhao
Run-Zhao
RZ
Yu
Wen-Kui
WK
Ye
Xiang-Hong
XH
Wang
Zhi-Ming
ZM
Wang
Xin-Ying
XY
Wang
Zhong-Qiu
ZQ
Ji
Da-Xi
DX
Li
Ning
N
Li
Jie-Shou
JS
D004322:Drainage; D004750:Enteral Nutrition; D006440:Hemofiltration; D006801:Humans; D010195:Pancreatitis / Q000628:therapy