A new catalyst for organic synthesis: mercuric triflate.
Herein, we describe Hg(OTf)(2) as a new catalytic system for organic synthesis, which can achieve the hydration of alkynes, C-C bond forming cyclizations, heterocycle synthesis and cyclization initiated by allylic alcohols at very high catalytic turnovers under mild conditions. The first solid-supported mercuric salt, silaphenylmercuric triflate, was also developed and found to act as a powerful catalyst for most Hg(OTf)(2)-catalyzed reactions.
Nishizawa
Mugio
M
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. mugi@ph.bunri-u.ac.jp
Imagawa
Hiroshi
H
Yamamoto
Hirofumi
H
D002384:Catalysis; D003500:Cyclization; D008628:Mercury / Q000737:chemistry; D017669:Mercury Compounds / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D017669:Mercury Compounds; D008698:Mesylates; D009930:Organic Chemicals; C510262:mercuric triflate; D008628:Mercury