title: Focus issue: external and internal regulators of immune responses.
abstract: This Focus Issue of Science Signaling, which complements the Science Special Issue on Innate Immunity (http://www.sciencemag.org/special/immunity), highlights the effects of viral and bacterial components on host cells, signaling pathways involved in regulating innate immune responses, and factors that modulate the functions of dendritic cells, which are required for effective adaptive immunity.
authors.forename: John F
authors.initials: JF
authors.lastname: Foley
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D000818:Animals; D054884:Host-Pathogen Interactions / Q000276:immunology; D006801:Humans; D007109:Immunity; D015398:Signal Transduction / Q000276:immunology*