title: Epidemiologic transition in mortality rate from circulatory diseases in Brazil.
abstract: BACKGROUND
  Circulatory diseases (CD) are the major cause of death in Brazil, being cerebrovascular diseases (CVD) predominant. In developed countries ischemic heart diseases (IHD) predominate.
  
  
  OBJECTIVE
  The objective of the present study was to investigate the ratio between cerebrovascular diseases/ischemic heart diseases (CVD/IHD) in males and females who were 30 years of age and older.
  
  
  METHODS
  Population estimates and mortality data for CD, IHD and CVD were provided by the Ministry of Health for the period between 1980 and 2005. The risk of death from IHD and CVD per 100,000 Brazilians and CVD/IHD ratio were analyzed in 10-year age ranges as of 30 years of age. The risk of death was adjusted by direct method by using 1960 world population as the standard population.
  
  
  RESULTS
  It was observed that the risk of death from IHD and CVD increased exponentially as age advanced. CVD was the major cause of death in Brazil until 1996, when IHD took the lead. In the period between 1980 and 2005 a 33.25% reduction in death risk from CD was observed in the Brazilian population. In that same period, the metropolitan area of the capital city of São Paulo reported a 45.44% reduction. The CVD/IHD ratio was shown to be higher among younger women - from 2.53 in 1980 down to 2.04 in 2005 in the Brazilian population, and from 2.76 in 1980 down to 1.96 in the metropolitan area of the capital city of São Paulo, with decreasing figures for subsequent age ranges. Among males, the CVD/IHD ratio was close to < 1 in all age ranges.
  
  
  CONCLUSIONS
  A transition in death risk from CD could be observed in Brazil, with current predominance of IHD.
authors.affiliation: Instituto do Coração, HC, FM, USP, São Paulo, SP, Brasil. pmansur@cardiol.br
authors.forename: Antonio de Padua
authors.initials: Ade P
authors.lastname: Mansur
authors.forename: Adriano Ibrahim A
authors.initials: AI
authors.lastname: Lopes
authors.forename: Desidério
authors.initials: D
authors.lastname: Favarato
authors.forename: Solange Desirée
authors.initials: SD
authors.lastname: Avakian
authors.forename: Luíz Antonio M
authors.initials: LA
authors.lastname: César
authors.forename: José Antonio F
authors.initials: JA
authors.lastname: Ramires
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death / Q000639:trends; D002561:Cerebrovascular Disorders / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000401:mortality; D012307:Risk Factors; D017678:Sex Distribution