title: Analgesic and diuretic properties of alpha-santalone from Polygonum flaccidum.
abstract: Polygonum flaccidum Meissn. is an annual herb, native to Bangladesh, and well known for its analgesic, anti-inflammatory, diuretic, purgative and insecticidal properties, and also for its use against snake-bites. The analgesic and the diuretic properties of alpha-santalone (1), isolated from the aerial parts of Polygonum flaccidum, were assessed by the acetic-acid-induced writhing method and the Lipschitz test, respectively. Complete (1)H and (13)C NMR data of 1 are also presented.
authors.affiliation: Phytopharmacology Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
authors.forename: Md Abdul
authors.initials: MA
authors.lastname: Mazid
authors.forename: Bidyut K
authors.initials: BK
authors.lastname: Datta
authors.forename: Lutfun
authors.initials: L
authors.lastname: Nahar
authors.forename: Md Abdur
authors.initials: MA
authors.lastname: Rashid
authors.forename: Sitesh C
authors.initials: SC
authors.lastname: Bachar
authors.forename: S A M Khairul
authors.initials: SA
authors.lastname: Bashar
authors.forename: Satyajit D
authors.initials: SD
authors.lastname: Sarker
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001952:Bridged-Ring Compounds / Q000302:isolation & purification / Q000494:pharmacology*; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology*; D028502:Polygonum / Q000737:chemistry*; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D001952:Bridged-Ring Compounds; D004232:Diuretics; D010936:Plant Extracts; D012717:Sesquiterpenes; C551894:alpha-santalone