title: 'Primary cutaneous mucormycosis during induction chemotherapy in a child with acute lymphoblastic leukemia'.
abstract: We report a child with acute lymphoblastic leukemia who developed primary cutaneous mucormycosis at the site of lumbar puncture during induction chemotherapy. Though high mortality rates are reported with invasive mucormycosis, prompt biopsy, early identification and antifungal therapy using a combination regime of amphotericin-B and rifampicin along with extensive surgical debridement led to complete cure of the lesions in the index case.
authors.affiliation: Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Jhuma
authors.initials: J
authors.lastname: Sankar
authors.forename: Sasi
authors.initials: S
authors.lastname: Arun
authors.forename: Mari Jeeva
authors.initials: MJ
authors.lastname: Sankar
authors.forename: Rachna
authors.initials: R
authors.lastname: Seth
authors.forename: Vasantha
authors.initials: V
authors.lastname: Thavraj
authors.forename: Sushil Kumar
authors.initials: SK
authors.lastname: Kabra
authors.forename: M
authors.initials: M
authors.lastname: Vasantha
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000139:chemically induced* / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012871:Skin Diseases / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D000666:Amphotericin B