A structural and functional homolog supports a general role for frataxin in cellular iron chemistry.
Bacillus subtilis YdhG lacks sequence homology, but demonstrates structural and functional similarity to the frataxin family, supporting a general cellular role for frataxin-type proteins in cellular iron homeostasis.
Qi
Wenbin
W
Evans Laboratory of Chemistry, The Ohio State University, 100 West, 18th Avenue, Columbus, OH 43210, USA.
Cowan
J A
JA
D001412:Bacillus subtilis / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism*; D018360:Crystallography, X-Ray; D006706:Homeostasis; D006801:Humans; D007501:Iron / Q000378:metabolism*; D033862:Iron-Binding Proteins / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D011487:Protein Conformation; D013997:Time Factors; D000096923:Frataxin
D001426:Bacterial Proteins; D007501:Iron; D033862:Iron-Binding Proteins; D000096923:Frataxin