title: [Drug resistance evolution of dichlorvos-resistant and cypermethrin-resistant strains of Culex pipiens pallens].
abstract: Susceptible strain of Culex pipiens pallens was selected with dichlorvos and cypermethrin for 42 generations in the laboratory. At generation 42, the resistance level to dichlorvos and cypermethrin was 12.2-fold and 534.3-fold, respectively, in comparison to their parent generations. The dichlorvos-resistant and cypermethrin-resistant strains were then conventionally bred for another 20 generations, the resistance level to dichlorvos and cypermethrin decreased to 6.1-fold and 83.3-fold, respectively. The results indicated that the two resistant strains showed different development of resistance.
authors.affiliation: Department of Parasitology, Jining Medical College, Jining, China.
authors.forename: Shi-Gen
authors.initials: SG
authors.lastname: Li
mesh_terms: D000818:Animals; D003465:Culex / Q000187:drug effects* / Q000235:genetics; D004006:Dichlorvos / Q000494:pharmacology*; D004351:Drug Resistance / Q000187:drug effects / Q000235:genetics*; D019143:Evolution, Molecular; D009032:Mosquito Control; D011722:Pyrethrins / Q000494:pharmacology*
chemical_list: D011722:Pyrethrins; C017160:cypermethrin; D004006:Dichlorvos