title: Phytochemical screening and polyphenolic antioxidant activity of aqueous crude leaf extract of Helichrysum pedunculatum.
abstract: We evaluated the in vitro antioxidant property and phytochemical constituents of the aqueous crude leaf extract of Helichrysum pedunculatum. The scavenging activity on superoxide anions, DPPH, H₂O₂, NO and ABTS; and the reducing power were determined, as well as the flavonoid, proanthocyanidin and phenolic contents of the extract. The extract exhibited scavenging activity towards all radicals tested due to the presence of relatively high total phenol and flavonoids contents. Our findings suggest that H. pedunculatum is endowed with antioxidant phytochemicals and could serve as a base for future drugs.
authors.affiliation: Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.
authors.forename: Olayinka A
authors.initials: OA
authors.lastname: Aiyegoro
authors.affiliation: Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.
authors.forename: Anthony I
authors.identifier: 0000-0002-9770-085X
authors.initials: AI
authors.lastname: Okoh
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D036562:Helichrysum / Q000737:chemistry* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry / Q000378:metabolism; D059808:Polyphenols / Q000737:chemistry* / Q000302:isolation & purification; D044945:Proanthocyanidins / Q000737:chemistry / Q000302:isolation & purification; D014867:Water / Q000737:chemistry
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts; D059808:Polyphenols; D044945:Proanthocyanidins; D014867:Water; C013221:proanthocyanidin