Alkaloids from Sophora flavescens Aition.
Although the quinolizidine alkaloids and flavonoids, the main active components of the traditional Chinese medicine Sophora flavescens, have been largely investigated, a new matrine alkaloid derivative 9alpha-hydroxy-7,11-dehydromatrine (1) and a rare 1,4-diazaindan-type alkaloid flavascensine (17), together with 15 known alkaloids, were isolated from S. flavescens. The structures were established on the basis of spectroscopic techniques.
Liu
Xiu-Jin
XJ
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
Cao
Mei-Ai
MA
Li
Wen-Hai
WH
Shen
Cheng-Shuo
CS
Yan
Shi-Qiang
SQ
Yuan
Cheng-Shan
CS
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D054837:Quinolizidines / Q000737:chemistry / Q000302:isolation & purification*; D029909:Sophora / Q000737:chemistry*
C553385:9alpha-hydroxy-7,11-dehydromatrine; D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D006576:Heterocyclic Compounds, 4 or More Rings; D054837:Quinolizidines