title: Successful pregnancy in a patient with portal hypertension secondary to portal vein thrombosis due to essential thrombocythaemia: a rare case.
abstract: Essential thrombocythaemia (ET) is a disease characterized by an increased platelet count, megakaryocytic hyperplasia and a hemorrhagic or thrombotic tendency. Pregnancy in patients with ET can have a favorable outcome. However, ET has also been reported to complicate pregnancy by recurrent abortions, intrauterine death, and fetal growth retardation due to placental infarctions. ET has an unusual prevalence of intraabdominal (hepatic, portal and mesenteric) vein thrombosis, especially in young patients, which can lead to portal hypertension. There are ample cases in the literature of both essential thrombocytosis complicating pregnancy and portal hypertension complicating pregnancy, but the coincidence of both conditions appears to be unique. In this case report, we report a successful pregnancy in a patient with a prior diagnosis of essential thrombocytosis with remote secondary portal vein thrombosis and portal hypertension (PH).
authors.affiliation: Department of Obstetrics and Gynecology, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey. esraesim@yahoo.com
authors.forename: Esra Esim
authors.initials: EE
authors.lastname: Buyukbayrak
authors.forename: Bahar
authors.initials: B
authors.lastname: Ergen
authors.forename: Ayse Yasemin
authors.initials: AY
authors.lastname: Karageyim Karsidag
authors.forename: Bulent
authors.initials: B
authors.lastname: Kars
authors.forename: Cem
authors.initials: C
authors.lastname: Turan
authors.forename: Elif
authors.initials: E
authors.lastname: Birtas Atesoglu
mesh_terms: D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D011169:Portal Vein; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D011256:Pregnancy Outcome; D013920:Thrombocythemia, Essential / Q000150:complications*; D020246:Venous Thrombosis / Q000150:complications*