Application of platelet function testing to the bedside.
The ability to test platelet reactivity in clinical practice could help in making informed decisions on both initiation and titration of anti-platelet drug therapies. However, many barriers still remain to the effective implementation of such techniques. Many tests used in the research literature are not yet available for practical, clinical use. Platelet aggregometry, while informative and currently available for bedside use, needs additional research before routine clinical use can be recommended. This review will highlight and update contemporary issues of bedside platelet testing for the clinician and comment on future areas of clinical research.
Williams
Craig D
CD
Department of Pharmacy Practice, OSU/OHSU College of Pharmacy, 3303 SW Bond Ave., CH12C Portland, Oregon, USA. williacr@ohsu.edu
Cherala
Ganesh
G
Serebruany
Victor
V
D001792:Blood Platelets / Q000187:drug effects*; D016903:Drug Monitoring / Q000379:methods*; D004359:Drug Therapy, Combination; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D010979:Platelet Function Tests; D019095:Point-of-Care Systems; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D018570:Risk Assessment
D010975:Platelet Aggregation Inhibitors