Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities.
The endothelin axis plays a major role in cardiovascular diseases and a number of human cancers. This review summarizes the work that has been published in the past ten years using labeled endothelin receptor ligands for the visualization of endothelin receptor expression in vivo.
Höltke
C
C
Department of Nuclear Medicine, University Hospital Münster, Münster, Germany. carsten.hoeltke@uni-muenster.de
Faust
A
A
Breyholz
H-J
HJ
Kopka
K
K
Schober
O
O
Riemann
B
B
Bremer
C
C
Schäfers
M
M
Wagner
S
S
D000595:Amino Acid Sequence; D000818:Animals; D016232:Endothelins / Q000096:biosynthesis / Q000378:metabolism*; D008024:Ligands; D057054:Molecular Imaging; D008969:Molecular Sequence Data; D051381:Rats; D017466:Receptors, Endothelin / Q000737:chemistry / Q000378:metabolism
D016232:Endothelins; D008024:Ligands; D017466:Receptors, Endothelin