title: [A clinicopathologic study of hepatic angiomyolipoma].
abstract: OBJECTIVE
  To investigate the clinicopathologic features, diagnosis and treatment of hepatic angiomyolipoma (HAML).
  
  
  METHODS
  The clinical, histopathological, treatment and prognosis data of 51 patients treated for HAML from October 1998 to October 2007 were retrospectively analyzed.
  
  
  RESULTS
  HAML had a female predilection (female/male = 41/10) and the mean age was 44 years old. The main symptoms were abdominal mass (33 cases) and abdominal pain or discomfort (15 cases), the other 2 cases presented as fever. Histopathologically, HAML was composed of a heterogeneous mixture of blood vessels, smooth muscle, and adipose cells. Immunohistochemical staining showed relatively high positive rate of HMB-45 (50/51), SMA (47/49) and S-100 (39/42). All 51 patients underwent partial hepatectomy. The mean hospital stay was 13.8 days and mean intraoperative blood loss was 263 ml. There was no recurrence or metastasis after a mean follow-up of 55.4 months.
  
  
  CONCLUSIONS
  HAML is a rare benign mesenchymal tumor of the liver. Definitive diagnosis of HAML depends on the pathohistological findings and HMB-45 positive myoid cell is an important diagnostic marker. Complete surgical resection is the optimal treatment for HAML with favorable prognosis.
authors.affiliation: Department of Hepatic Surgery, Zhongshan Hospital Fudan University, Shanghai 200032, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Jia
authors.initials: J
authors.lastname: Fan
authors.forename: Lun-xiu
authors.initials: LX
authors.lastname: Qin
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Hui-chuan
authors.initials: HC
authors.lastname: Sun
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.forename: Qing-hai
authors.initials: QH
authors.lastname: Ye
authors.forename: Shuang-jian
authors.initials: SJ
authors.lastname: Qiu
authors.forename: Zhao-you
authors.initials: ZY
authors.lastname: Tang
mesh_terms: D000293:Adolescent; D000328:Adult; D018207:Angiomyolipoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult