Arylchlorogermanes/TBAF/"moist" toluene: a promising combination for Pd-catalyzed Germyl-Stille cross-coupling.
The trichlorophenyl,- dichlorodiphenyl,- and chlorotriphenylgermanes undergo Pd-catalyzed cross-couplings with aryl bromides and iodides in the presence of TBAF in toluene with addition of the measured amount of water. One chloride ligand on the Ge center allows efficient activation by fluoride to promote transfer of one, two, or three phenyl groups from the organogermane precursors.
Zhang
Zun-Ting
ZT
Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, USA.
Pitteloud
Jean-Philippe
JP
Cabrera
Laura
L
Liang
Yong
Y
Toribio
Myrdich
M
Wnuk
Stanislaw F
SF
D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D014050:Toluene / Q000737:chemistry*
D006846:Hydrocarbons, Halogenated; D014050:Toluene; D010165:Palladium