Findings of clinical trials that evaluate the impact of medical therapies on progression of atherosclerosis.
BACKGROUND
Arterial wall imaging has been increasingly employed in clinical trials to evaluate the impact of medical therapies on progression of atherosclerosis.


METHODS
A selective overview of major findings from clinical trials that assessed the impact of medical therapies on atherosclerosis progression.


RESULTS
Targeting established risk factors including LDL cholesterol, HDL cholesterol and blood pressure has a beneficial impact on disease progression.


CONCLUSIONS
As a result, vascular imaging has been employed in the early evaluation of experimental therapies.
Lavoie
Andrea
A
Cleveland Clinic, Cleveland, OH, USA.
Uno
Kiyoko
K
Bayturan
Ozgur
O
Nicholls
Stephen J
SJ
D000792:Angiography / Q000379:methods; D050197:Atherosclerosis / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D001794:Blood Pressure; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL