Pneumocystis jirovecii and cystic fibrosis in France.
We retrospectively investigated 76 patients with cystic fibrosis for the presence of Pneumocystis jirovecii, by performing real-time PCR and nested-PCR assays on 146 archival sputum specimens. P. jirovecii was detected in only 1 patient (1.3%) showing that in our region (Brest, France), the fungus is rarely involved in pulmonary colonization in patients with cystic fibrosis.
Gal
Solène Le
SL
Faculté de Médecine, Université Européenne de Bretagne, Université de Brest, LUBEM-EA 3882, IFR 148, Brest, France.
Héry-Arnaud
Geneviève
G
Ramel
Sophie
S
Virmaux
Michèle
M
Damiani
Céline
C
Totet
Anne
A
Nevez
Gilles
G
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003550:Cystic Fibrosis / Q000150:complications*; D004271:DNA, Fungal / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D045363:Pneumocystis carinii / Q000302:isolation & purification*; D011020:Pneumonia, Pneumocystis / Q000453:epidemiology* / Q000382:microbiology; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012189:Retrospective Studies; D013183:Sputum / Q000382:microbiology; D055815:Young Adult
D004271:DNA, Fungal