title: Peculiarities of synchronic and metachronous malignant tumors of reproductive system in thyroid gland cancer.
abstract: The aim of our study was to establish a reliable method for the evaluation of mechanisms of tumor development and early diagnostics of tumors of the breast and female genital organs in patients with thyroid gland cancer. For this purpose 29 female patients with thyroid gland cancer and different accompanied diseases of reproductive tract system have been studied for six months. During this period patients' clinical, hormonal and ultrasonographyc indicators were analyzed. The study showed that, suppressive therapy is preventive method in development of pre-cancer diseases of reproductive system. Thyrotrophic hormone hypersecretion (long current latent hypothyroidism) conditions thyroid gland proliferative activity; high level of gonadoliberin provides proliferative activity of organs of reproductive system.
authors.affiliation: Tbilisi State Medical University, Georgian-German Specialized Oncology Clinic.
authors.forename: T
authors.initials: T
authors.lastname: Makaridze
authors.forename: K
authors.initials: K
authors.lastname: Mardaleishvili
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000601:surgery; D013965:Thyroidectomy; D055815:Young Adult