Measuring cis-acting regulatory variants genome-wide: new insights into expression genetics and disease susceptibility.
A recent large-scale allelic expression analysis shows that cis-acting regulatory variants might reveal some of the 'missing heritability' component of complex disorders, which could lead to potential therapy and prevention breakthroughs.
Sadee
Wolfgang
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Program in Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.