title: Vaginal delivery after Misgav-Ladach cesarean section--is the risk of uterine rupture acceptable?
abstract: OBJECTIVE
  To evaluate whether the single-layer closure as is a routine by the Misgav-Ladach method compared to the double-layer closure as used by the Dörfler cesarean method is associated with an increased risk of uterine rupture in the subsequent pregnancy and delivery.
  
  
  METHODS
  The analysis is retrospective and is based on medical documentation of the Clinic for Gynecology and Obstetrics, University Clinical Centre, Tuzla, Bosnia and Herzegovina. All patients with one previous cesarean section who attempted vaginal birth following cesarean section were managed from 1 January 2002 to 31 December 2008. Exclusion criteria included multiple gestation, greater than one previous cesarean section, previous incision other than low transverse, gestational age at delivery less than 37 weeks and induction of delivery. We identified 448 patients who met inclusion criteria.
  
  
  RESULTS
  We found that 303 patients had a single-layer closure (Misgav-Ladach) and 145 had a double-layer closure (Dörffler) of the previous uterine incision. There were 35 cases of uterine rupture. Of those patients with previous single-layer closure, 5.28% (16/303) had a uterine rupture compared to 13.11% (19/145) in the double-layer closure group (p<0.05).
  
  
  CONCLUSIONS
  We have not found that a Misgav-Ladach cesarean section method (single-layer uterine closure) might be more likely to result in uterine rupture in women who attempted a vaginal birth after a previous cesarean delivery. This cesarean section method should find its confirmation in everyday clinical practice.
authors.affiliation: Clinic of Gynecology and Obstetrics, University Clinical Center, Tuzla, Bosnia and Herzegovina. i.hudic@bih.net.ba
authors.forename: Igor
authors.initials: I
authors.lastname: Hudić
authors.forename: Zlatan
authors.initials: Z
authors.lastname: Fatusić
authors.forename: Lejla
authors.initials: L
authors.lastname: Kamerić
authors.forename: Mladen
authors.initials: M
authors.lastname: Misić
authors.forename: Indira
authors.initials: I
authors.lastname: Serak
authors.forename: Anela
authors.initials: A
authors.lastname: Latifagić
mesh_terms: D000328:Adult; D017522:Bosnia and Herzegovina / Q000453:epidemiology; D002585:Cesarean Section / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D012189:Retrospective Studies; D012306:Risk; D013536:Suture Techniques / Q000009:adverse effects*; D014597:Uterine Rupture / Q000453:epidemiology / Q000209:etiology*; D016064:Vaginal Birth after Cesarean / Q000009:adverse effects* / Q000706:statistics & numerical data; D055815:Young Adult