[Compatability chemistry of acid-alkaline pair medicine of Ephedra sinica and Glycyrrhiza uralencis in Maxing Shigan decoction].
OBJECTIVE
To investigate the change regularity of ephedrine and glyrihhzine acid in Ephedra sinila and Glycyrrhiza uralencis pair medicines and in Maxing Shigan decoction.


METHODS
The contents of ephedrine and glycyrrhizic acid were determined by HPLC in samples of E. sinica extracts, G. uralencis extracts, pair medicines extracts of Maxing Shigao decoction sinica and G. uralencis, and extracts of E. sinica.


RESULTS
There were no significant difference in ephedrine contents amoung different samples; the contents of glycyrrhizic acid were lower in decoctions of Maxing Shigan decoction than in G. uralencis decoction and pair medicines extracts.


CONCLUSIONS
Macromolecular complex was NOT formed by ephedrine and Glycyrrhizic acid in decoctions containing pair medicines of E. sinica and G. uralencis.
Pei
Xiangping
X
Department of Chinese Materia Medica, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China.
Pei
Miaorong
M
Duan
Xiujun
X
D002626:Chemistry, Pharmaceutical; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D029790:Ephedra sinica / Q000737:chemistry*; D004809:Ephedrine / Q000737:chemistry*; D006035:Glycyrrhiza / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D019695:Glycyrrhizic Acid; D004809:Ephedrine