[The potential of the analgetic placebo effect - s3-guideline recommendation on the clinical use for acute and perioperative pain management].
The effectiveness of the analgetic placebo effect has been confirmed by several meta-analyses: not only can substances without active agents (placebos) achieve (hypo-) analgetic effectiveness, but also the effectiveness of active analgetics can be increased by added placebo effects. For this reason the new AWMF-S3 guidelines (DIVS 2009, www.awmf.org ) on the "treatment of acute and perioperative pain" recommend the clinical use of placebo effects and the avoidance of nocebo effects. The point is not to use placebos as a substitute for analgetics, but rather to add placebo effects on to those of analgetics.
Klinger
Regine
R
D000208:Acute Disease; D000700:Analgesics / Q000627:therapeutic use*; D004723:Endorphins / Q000502:physiology; D017408:Guidelines as Topic; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D019990:Perioperative Care; D015990:Placebo Effect; D010919:Placebos / Q000627:therapeutic use*
D000700:Analgesics; D004723:Endorphins; D010919:Placebos