title: Inhomogeneous bone marrow uptake caused by G-CSF mimics multiple bone metastases on FDG-PET.
abstract: Administration of granulocyte colony stimulating factor can cause homogeneous hypermetabolic activity of bone marrow in positron emission tomography using F-18-fluorodeoxyglucose. We report a case in which positron emission tomography demonstrated multiple foci of hypermetabolic activity in the bone marrow, which was considered an early effect of granulocyte colony stimulating factor, and not multiple osseous metastases.
authors.affiliation: Department of Diagnostic Radiology, Kyoto University Hospital, Sakyo-ku, Kyoto, Japan. ynakamo1@kuhp.kyoto-u.ac.jp
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakamoto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Suga
authors.forename: Tadashi
authors.initials: T
authors.lastname: Hara
authors.forename: Koichi
authors.initials: K
authors.lastname: Ishizu
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
mesh_terms: D016477:Artifacts; D001853:Bone Marrow / Q000187:drug effects / Q000378:metabolism*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000556:secondary*; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography
chemical_list: D019788:Fluorodeoxyglucose F18; D016179:Granulocyte Colony-Stimulating Factor