title: Clinical comparison of psoriasis in Korean adults and children: correlation with serum anti-streptolysin O titers.
abstract: Psoriasis is a relatively common disorder in children and can be triggered by an upper respiratory tract infection. The aim of this study was to compare the clinical features of psoriasis in children and adult. In addition, we evaluated the relationship between anti-streptolysin O (ASO) titers and the clinical features of psoriasis. A total of 30 childhood psoriasis patients and 30 adult psoriasis patients were evaluated. Childhood psoriasis had a facial predominance when compared with the adult psoriasis. The childhood psoriasis patients with high ASO titers had guttate psoriasis more frequently than patients with normal ASO titers. In children with plaque-type psoriasis, psoriasis area and severity index score was increased in the high ASO titer group than normal ASO titer group. In conclusion, if the children with psoriasis show increased ASO titer, the physician should pay attention to the worsening of the psoriasis. Furthermore, early treatment of streptococcal infections might be beneficial in childhood psoriasis.
authors.affiliation: Department of Dermatology, Ajou University School of Medicine, 5 Wonchon-Dong, Yeongtong-Gu, Suwon, 443-721, South Korea.
authors.forename: Sue Kyung
authors.initials: SK
authors.lastname: Kim
authors.forename: Hee Young
authors.initials: HY
authors.lastname: Kang
authors.forename: You Chan
authors.initials: YC
authors.lastname: Kim
authors.forename: Eun-So
authors.initials: ES
authors.lastname: Lee
mesh_terms: D000328:Adult; D000367:Age Factors; D000906:Antibodies / Q000378:metabolism; D001426:Bacterial Proteins / Q000276:immunology; D002648:Child; D018450:Disease Progression; D005145:Face / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000097:blood / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D012141:Respiratory Tract Infections / Q000097:blood / Q000150:complications / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D013290:Streptococcal Infections / Q000097:blood / Q000150:complications / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D013291:Streptococcus / Q000276:immunology* / Q000472:pathogenicity; D013301:Streptolysins / Q000276:immunology
chemical_list: D000906:Antibodies; D001426:Bacterial Proteins; D013301:Streptolysins; C025964:streptolysin O