[Case-control study on the relationship between varicella vaccine inoculation and varicella morbidity].
OBJECTIVE
To analyse and find out the influence of varicella vaccine inoculation to varicella morbidity.


METHODS
The case-control study was conducted. During October 1st 2006 to July 31st 2007, 193 varicella cases were identified, and 342 control subjects were matched.


RESULTS
1. The proportion of nonvaccinated in case group was higher than that of control group (odds ratio 1.49, 95% confidence interval 0.99-2.24, P=0.043). 2. The morbidity to the people who received one dose varicella vaccine was obviously higher than that of people who reiceived more than 2 dose (odds ratio 3.04, 95% confidence interval 1.25-7.72, P=0.007). 3. Significant differences were not observed between the domestic vaccine and the impoted vaccine (odds ratio 1.38, 95% confidence interval 0.53-3.71 P=0.483). 4. Clinical symptom of the vaccine was lighter than that of the unvaccinated, and rash was not typical.


CONCLUSIONS
1. Inoculation varicella vaccine was effective measures to prevent varicella. 2. The risk to get varicella of one-dose vaccinated was higher than that of more than 2-dose vaccinated. 3. The effectiveness of domestic varicella vaccine was as high as impoted vaccine. 4. The clinical symptom of varicella would be alleviated if the person had vaccinated.
Cai
Jun-Fang
JF
Centre for Disease Control and Prevention of Chaoyang District, Beijing. 100021, China.
Luo
Feng-Ji
FJ
Li
Jin-Hua
JH
D000293:Adolescent; D016022:Case-Control Studies; D002644:Chickenpox / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*; D019433:Chickenpox Vaccine / Q000008:administration & dosage* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009017:Morbidity; D014611:Vaccination
D019433:Chickenpox Vaccine