title: DPT (dose provocative test) test for proving allergic reactions to local anaesthetics.
abstract: To prove the existence of possible allergic reaction to local anaesthetic by the recommendations and experience of the current literature, an assortment or mosaic of complementary diagnostic tests is made by: anamnesis and a clinical picture and in vivo skin allergy tests - tests of the humeral and cellular immune response. Anamnesis and the clinical picture are mostly in metaphorical characteristics because we are not direct observers of the happenings and manifestations. If we use anaesthetics every day there is a possibility of side effects. The main aim is to determine the real persistence of hypersensitive reactions. For diagnosing the hypersensitive reactions in this task, in vivo tests were done on 50 examinees with plus (+) anamnesis for unwanted reactions from previous anesthetics applications (tooth extraction). The accent is put on the DPT (dose provocation test). Based on SAT allergic testing the percentage is 4.0%. We used the relative statement of the patient as support for the real picture of the event. The DPT test is considered the only in vivo test that may exclude the risk of allergic reaction, because of its specificity and high risk. Besides the negative results from DPT we cannot be absolutely sure and rely on the test results, including the results of anaesthetic application, because the risk of allergic reaction of patients who have been tested is not higher than that of the patients who have not been tested.
authors.affiliation: Oral Surgery Department, Faculty of Dentistry, Skopje, R. Macedonia. buba stom@yahoo.com
authors.forename: Lj
authors.initials: Lj
authors.lastname: Simjanovska
authors.forename: M
authors.initials: M
authors.lastname: Marsenić
authors.forename: S
authors.initials: S
authors.lastname: Simjanovski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000766:Anesthesia, Dental; D000779:Anesthetics, Local / Q000009:adverse effects*; D002648:Child; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local