title: Rubella seroepidemiology and catch-up immunization among pregnant women in Taiwan: comparison between women born in Taiwan and immigrants from six countries in Asia.
abstract: Rubella vaccination in Taiwan started in 1986; mass vaccination was introduced into the national immunization program in 1992. In recent years, 17-31% of all marriages in Taiwan have been between Taiwanese men and foreign women. The aim of this study was to analyze rubella seroepidemiology and the rate of catch-up immunization in women. We recruited 10,089 pregnant women, including 1,920 immigrants, who had received prenatal examinations during 1999-2006. The rates of seronegativity among global, Taiwan-born, and non-Taiwan-born pregnant women were 14.0%, 11.9%, and 23.1%, respectively. The seronegativity of rubella antibodies decreased from 28.2% for Taiwan-born women born before September 1971 to 8.0% for those born thereafter. The rates of rubella catch-up immunization among global, Taiwan-born, and non-Taiwan-born pregnant women were 28.6%, 20.5%, and 42.2%, respectively. Our results suggest that substantial numbers of older Taiwan-born women and immigrant women remain susceptible to rubella infection.
authors.affiliation: Department of Laboratory Medicine, Fooying University Hospital, Pingtung, Taiwan. x6053@ms25.hinet.net
authors.forename: Ching-Chiang
authors.initials: CC
authors.lastname: Lin
authors.forename: Chun-Yuh
authors.initials: CY
authors.lastname: Yang
authors.forename: Ching-Tang
authors.initials: CT
authors.lastname: Shih
authors.forename: Bai-Hsiun
authors.initials: BH
authors.lastname: Chen
authors.forename: Yeou-Lih
authors.initials: YL
authors.lastname: Huang
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D011247:Pregnancy; D012409:Rubella / Q000453:epidemiology*; D012411:Rubella Vaccine / Q000008:administration & dosage*; D012412:Rubella virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D013624:Taiwan
chemical_list: D000914:Antibodies, Viral; D012411:Rubella Vaccine