Tetrasubstituted allenes by Pd0-catalyzed three-component tandem Michael addition/cross-coupling reaction.
A Pd(0)-catalyzed three-component tandem Michael addition/cross-coupling reaction of electron-deficient enynes with nucleophiles and aryl halides was developed, which provides general, efficient, and regioselective access to multi-functionalized tetra-substituted allenes.
Xiao
Yuanjing
Y
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N, Zhongshan Road, Shanghai 200062, P. R. China.
Zhang
Junliang
J
D000466:Alkadienes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000466:Alkadienes; D000480:Alkynes; D006846:Hydrocarbons, Halogenated; C025947:propadiene; D010165:Palladium