Somatosensory-related gamma-, beta- and alpha-augmentation precedes alpha- and beta-attenuation in humans.
OBJECTIVE
Several human studies have demonstrated that the amplitudes of cortical oscillations are altered by various sensorimotor and cognitive tasks. Event-related augmentation of gamma oscillations and attenuation of alpha and beta oscillations have been often used as surrogate markers of cortical activation elicited by tasks especially in presurgical identification of eloquent cortices. In the present study, we addressed a question whether somatosensory-related gamma augmentation 'precedes' or 'co-occurs with' somatosensory-related attenuation of alpha-beta oscillations.


METHODS
We studied 10 patients who underwent intracranial electrocorticography for epilepsy surgery, and determined the temporal and spatial characteristics of median-nerve somatosensory-related amplitude changes at gamma- (30-100Hz), beta- (14-28Hz) and alpha-band (8-12Hz) oscillations.


RESULTS
We found that somatosensory-related gamma augmentation involving the post- and pre-central gyri evolved into beta and alpha augmentation, which was subsequently followed by beta and alpha attenuation involving the post- and pre-central gyri.


CONCLUSIONS
These observations support the hypothesis that somatosensory-related gamma augmentation but not alpha-beta attenuation represents the initial cortical processing for external somatosensory stimuli. Somatosensory-related alpha-beta attenuation appears to represent a temporally distinct stage of somatosensory processing.


CONCLUSIONS
The present study has increased our understanding of event-related gamma augmentation and alpha-beta attenuation seen on electrocorticography.
Fukuda
Miho
M
Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit Medical Center, Detroit, MI 48201, USA.
Juhász
Csaba
C
Hoechstetter
Karsten
K
Sood
Sandeep
S
Asano
Eishi
E
D000200:Action Potentials / Q000502:physiology; D000293:Adolescent; D000465:Algorithms; D000513:Alpha Rhythm; D001611:Beta Rhythm; D001683:Biological Clocks / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004558:Electric Stimulation; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology; D009415:Nerve Net / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012684:Sensory Thresholds / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013003:Somatosensory Cortex / Q000502:physiology*; D013997:Time Factors; D055698:Touch Perception / Q000502:physiology