title: [Treatment experience of severe acute pancreatitis on 1033 cases.].
abstract: OBJECTIVE
  To summary the treatment experience of severe acute pancreatitis (SAP).
  
  
  METHODS
  From January 1997 to March 2009, a total of 1033 patients suffered SAP were admitted with a mean APACHE II score 12.0 +/- 4.3. There were 622 males and 411 females, aged from 13 to 98 years old. All patients were cared by the multidisciplinary team with intensivist, endoscopists, gastroenterologists, radiologist, nephrologist and surgeons.Patients treated in SICU in the early phase of the disease. In these 1033 patients, 365 cases received mechanical ventilation, 218 with tracheotomy, 159 cases received high-volume continuous venovenous hemofiltration (CVVH), 179 received nasobiliary drainage, 513 were treated with early enteral nutrition. CT-guided percutaneous catheter drainge for peripancreatic fluid collection was pefromed for 477 times and 438 patients received surgical debridement for infected pancreatic necrosis.
  
  
  RESULTS
  In all these 1033 cases, 975 patients (94.4%) survived, and 38 patients died (3.7%). The mortality of patients who received surgical debridement for infected pancreatic necrosis was 7.1% (31/438).
  
  
  CONCLUSIONS
  The muti-discipline management of severe acute pancreatitis can remarkably improve the prognosis of patients.
authors.affiliation: Research Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Wei-Qin
authors.initials: WQ
authors.lastname: Li
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Tong
authors.forename: Zhu-Fu
authors.initials: ZF
authors.lastname: Quan
authors.forename: Run-Zhao
authors.initials: RZ
authors.lastname: Zhao
authors.forename: Wen-Kui
authors.initials: WK
authors.lastname: Yu
authors.forename: Xiang-Hong
authors.initials: XH
authors.lastname: Ye
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Wang
authors.forename: Xin-Ying
authors.initials: XY
authors.lastname: Wang
authors.forename: Zhong-Qiu
authors.initials: ZQ
authors.lastname: Wang
authors.forename: Da-Xi
authors.initials: DX
authors.lastname: Ji
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.forename: Jie-Shou
authors.initials: JS
authors.lastname: Li
mesh_terms: D004322:Drainage; D004750:Enteral Nutrition; D006440:Hemofiltration; D006801:Humans; D010195:Pancreatitis / Q000628:therapy