title: Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery.
abstract: The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran-spermine conjugates.
authors.affiliation: Department of Chemistry, BK21 Program, Polymer Research Institute, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea.
authors.forename: Soo Kyung
authors.initials: SK
authors.lastname: Kim
authors.forename: Kyeng Min
authors.initials: KM
authors.lastname: Park
authors.forename: Kaushik
authors.initials: K
authors.lastname: Singha
authors.forename: Jeeyeon
authors.initials: J
authors.lastname: Kim
authors.forename: Youngjoo
authors.initials: Y
authors.lastname: Ahn
authors.forename: Kimoon
authors.initials: K
authors.lastname: Kim
authors.forename: Won Jong
authors.initials: WJ
authors.lastname: Kim
mesh_terms: D003911:Dextrans / Q000737:chemistry / Q000378:metabolism; D016503:Drug Delivery Systems; D005690:Galactose / Q000737:chemistry / Q000378:metabolism*; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism*; D022781:Hepatocytes / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D047028:Macrocyclic Compounds / Q000737:chemistry / Q000378:metabolism*; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D013096:Spermine / Q000737:chemistry / Q000378:metabolism; D000099246:Cucurbit(n)urils
chemical_list: D003911:Dextrans; D005690:Galactose; D047028:Macrocyclic Compounds; D046911:Macromolecular Substances; D013096:Spermine; D000099246:Cucurbit(n)urils