Successful surgical treatment of medically refractory epilepsy after chemotherapy in a child with leukemia: a case report.
BACKGROUND
Mesial temporal sclerosis associated with acute lymphoblastic leukemia has been rarely reported.


METHODS
We report a case of a 15-year-old boy with acute lymphoblastic leukemia who developed medically refractory temporal lobe epilepsy in a long time period after chemotherapy, and successfully treated with surgical resection.


CONCLUSIONS
To our knowledge, this is the first description of a leukemic child with medically refractory temporal lobe epilepsy who achieved seizure-freedom postoperatively during the long-term follow-up. The clinical history and details of the underlying pathophysiological background and treatment of this complication are discussed in this case report.
Arhan
Ebru
E
Department of Pediatric Neurology, Gazi University Medical Faculty, Ankara, Turkey. petekarhan@yahoo.com.tr
Kaya
Zühre
Z
Serdaroğlu
Ayse
A
Ozcelik
Aysima Akturk
AA
Bilir
Erhan
E
Durdağ
Emre
E
Kurt
Gökhan
G
Albayrak
Meryem
M
D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D004827:Epilepsy / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome
D000927:Anticonvulsants; D000970:Antineoplastic Agents