title: Executive summary of the workshop on infection in the high-risk infant.
abstract: For newborn infants in intensive care units, the morbidity and mortality from infection continues to be a major burden despite advances in neonatal care. Infants are at risk for early-onset, late-onset as well as hospital-acquired infections. Research studies are needed to optimize timely diagnosis and treatment, and develop patient-specific and system-wide strategies to prevent perinatal and neonatal infections. To address the knowledge gaps that preclude optimal, evidence-based care in this critical field, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) organized a workshop in August 2008. In this paper, we provide a summary of the discussions, focusing on major knowledge gaps, and prioritized suggestions for research in this area.
authors.affiliation: Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. higginsr@mail.nih.gov
authors.forename: R D
authors.initials: RD
authors.lastname: Higgins
authors.forename: C J
authors.initials: CJ
authors.lastname: Baker
authors.forename: T N K
authors.initials: TN
authors.lastname: Raju
mesh_terms: D002408:Catheters, Indwelling / Q000009:adverse effects; D021821:Communicable Diseases, Emerging; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007249:Inflammation / Q000276:immunology* / Q000382:microbiology; D007363:Intensive Care Units, Neonatal; D012307:Risk Factors; D018805:Sepsis / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control*