title: The pig tapeworm Taenia solium, the cause of cysticercosis: Biogeographic (temporal and spacial) origins in Madagascar.
abstract: Cysticercosis is a serious public health problem in Madagascar. The prevalence rate of active cysticercosis reached 21% in regions with a high level of livestock farming. Taenia solium of African-American and Asian genotypes are both present on the island. The times of divergence of the 13 specimens studied suggests a very ancient diversification of T. solium. These events are widely thought to be prior to the domestication of pigs, and seem to follow the expansion of Homo in Asia. Multiple human migrations and the diversity of potential intermediate hosts may have led to a complex epidemiological situation on the island.
authors.affiliation: EA3174 NETEC Neuroépidémiologie Tropicale et Comparée, Faculté de Médécine, 2 rue du Docteur Marcland, 87025 Limoges, France. lomichelet@hotmail.com
authors.forename: Lorraine
authors.initials: L
authors.lastname: Michelet
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Carod
authors.forename: Mahenintsoa
authors.initials: M
authors.lastname: Rakontondrazaka
authors.forename: Laurence
authors.initials: L
authors.lastname: Ma
authors.forename: Frédérick
authors.initials: F
authors.lastname: Gay
authors.forename: Catherine
authors.initials: C
authors.lastname: Dauga
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000453:epidemiology*; D018509:DNA, Helminth / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics; D019143:Evolution, Molecular; D005838:Genotype; D005843:Geography; D016013:Likelihood Functions; D008270:Madagascar / Q000453:epidemiology; D010802:Phylogeny; D011110:Polymorphism, Genetic; D013552:Swine / Q000469:parasitology; D041201:Taenia solium / Q000145:classification / Q000235:genetics*
chemical_list: D018509:DNA, Helminth; D004272:DNA, Mitochondrial