title: [Symmetrical phlebothrombosis of lower extremities resulting from congenital malformation of vena cava inferior].
abstract: Agenesis/atresia ofvena cava inferior is a rare congenital anomaly, caused by an aberrance of embryonal venous system development. This is in most cases asymptomatic, because of well developed collateral venous circulation. However, in some cases, it can be manifested with occurence of deep thrombosis in area of pelvis and lower limbs. In this case report, we repon a 21 year old male with painful swelling of both lower limbs. Ultrasonographic examination revealed a bilateral thrombosis in deep venous system of lower limbs and pelvis. Subsequent CT angiography showed atresia ofinfrarenal segment ofvena cava inferior. According to the CT image thrombotic proces affected also collateral venous system, that joined mostly to vena azygos and hemiazygos. Examination of coagulation system didn't reveal a procuring cause ofthrombotic occurrence. We realized a systemic trombolysis with streptokinase during 5 days. Starting from the fifth day we administered a low molecular weight heparin in anticoagulant dose. This treatment showed a good clinical effect. Pacient was discharged with a long-term oral warfarin therapy in combination with acetylsalicylic acid. In next four months of taking recommended therapy no relapse of thrombotic process nor evolvement of bleeding complication was observed.
authors.affiliation: I. interná klinika Lekárskej fakulty UK a FNsP Bratislava, Slovenská republika. halcin@zoznam.sk
authors.forename: A
authors.initials: A
authors.lastname: Halcín
authors.forename: E
authors.initials: E
authors.lastname: Kovácová
authors.forename: F
authors.initials: F
authors.lastname: Mikla
authors.forename: A
authors.initials: A
authors.lastname: Reptová
authors.forename: J
authors.initials: J
authors.lastname: Bedeová
mesh_terms: D000328:Adult; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D014682:Vena Cava, Inferior / Q000002:abnormalities*; D020246:Venous Thrombosis / Q000209:etiology*; D055815:Young Adult