Do comorbidities influence objective and subjective recovery rates of nasal polyposis?
OBJECTIVE
To investigate the clinical and laboratory outcomes both objectively and subjectively in nasal polyposis patients with or without comorbidity (CoM; asthma and allergy).


METHODS
Thirty-three nasal polyposis patients (13 women and 20 men) were included into the study. Their mean age was 39.23 +/- 9.13 years. CoM(+) and CoM(-) nasal polyposis patients were compared with each other. Evaluations contained endoscopic nasal examination, acoustic rhinometry, rhinomanometry, visual analog scale score of nasal blockage, olfactory function score, respiratory function test, skin prick tests, and paranasal sinus computed tomography.


RESULTS
Recovery was statistically significant in all observed evaluations for endoscopic and radiologic staging, nasal obstruction, and sense of smell compared with the first evaluation in all patients regardless of the subgroups. Although objective measurements of respiratory functions did not show any change, clinical improvement was detected in CoM(+) patients with a decrease of need to their antiasthmatic medical treatment.


CONCLUSIONS
Results of CoM(+) patients led to no statistical difference when compared with CoM(-) subgroup. When applying predefined nasal polyposis treatment protocol, the polyp patients with CoMs do not need close follow-up compared to the patients without CoMs.
Akarcay
Mustafa
M
Otorhinolaryngology Department, Medical Faculty, Inonu University, Malatya, Turkey.
Ekici
Nur
N
Miman
Murat C
MC
Firat
Yezdan
Y
Bayindir
Tuba
T
Selimoglu
Erol
E
D000328:Adult; D001249:Asthma / Q000150:complications; D015897:Comorbidity; D004724:Endoscopy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D008297:Male; D015508:Nasal Obstruction / Q000209:etiology; D009298:Nasal Polyps / Q000150:complications / Q000601:surgery*; D011446:Prospective Studies; D012129:Respiratory Function Tests; D025363:Rhinomanometry; D012307:Risk Factors; D012882:Skin Tests; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome