title: Acanthamoeba keratitis with Curvularia co-infection.
abstract: We report a case of Acanthamoeba keratitis with Curvularia co-infection. Acanthamoeba and fungal co-infection have been uncommonly reported in literature, worldwide. A classical history with a strong clinical suspicion and experienced laboratory personnel with systematic examination of corneal scrapings for bacterial, viral, parasitic and fungal causes are imperative for accurate diagnosis. Early diagnosis of Acanthamoeba keratitis or fungal infection followed by aggressive and appropriate treatment with effective agents is critical for the retention of good vision. Acanthamoeba keratitis is difficult to diagnose and, despite improvement in treatment options, may culminate in prolonged morbidity and significant loss of visual acuity. This case emphasizes the important role played by clinical microbiologists in making prompt diagnosis which can ultimately reduce visual morbidity.
authors.affiliation: Zoonotic Division, National Institute of Communicable Diseases, New Delhi, India.
authors.forename: N
authors.initials: N
authors.lastname: Gupta
authors.forename: J C
authors.initials: JC
authors.lastname: Samantaray
authors.forename: S
authors.initials: S
authors.lastname: Duggal
authors.forename: V
authors.initials: V
authors.lastname: Srivastava
authors.forename: C S
authors.initials: CS
authors.lastname: Dhull
authors.forename: U
authors.initials: U
authors.lastname: Chaudhary
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification*; D015823:Acanthamoeba Keratitis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D000328:Adult; D000818:Animals; D001203:Ascomycota / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D009181:Mycoses / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology