[Clinical analysis of donor hepatectomy in living donor liver transplantation: report of 74 cases].
OBJECTIVE
To evaluate the living donor selection, donor hepatectomy technique, and surgical complication in living donor liver transplantation.


METHODS
From June 2007 to July 2008, 74 consecutive cases living donor hepatectomy were performed by the same surgical team. Seventy-four donors (64 males and 10 females) with a mean age of 29.2 years old passed the donor liver assessment and evaluation program successfully. The hepatectomy procedure types contained right liver resection (n = 72), of which 27 cases harvested the middle hepatic vein and 45 cases not, left liver resection contain middle hepatic vein (n = 1) and left lateral resection (n = 1).


RESULTS
Of all the donors, operation time was (6.5 +/- 6.2) hours, the mean blood loss was 300 ml (100 - 500 ml) and didn't accept foreign blood transfusion. The maximum alanine aminotransferase (ALT) level was (229.5 +/- 108.6) U/L, the ALT returned to normal time was (12.7 +/- 4.8) d, the maximum total bilirubin (TB) level was (78.7 +/- 44.3) micromol/L, the TB returned to normal time was (8.8 +/- 2.7) d, and the mean hospital stay time was 14 days (7 - 28 d). The complications included bile leak (n = 1), cut surface hemorrhage (n = 1) and anaphylactoid purpura (n = 1). All the donors returned to normal work and life finally.


CONCLUSIONS
Precisely evaluating donor blood vascular and biliary anatomy before operation, keeping the blood vascular and bile duct integrity during operation and monitoring complication to solve it immediately after operation is crucial to ensure donor safety and recovering successfully.
Zhang
Ya-min
YM
Department of Transplantation, First Central Hospital of Tianjin, Tianjin 300192, China.
Zhu
Zhi-jun
ZJ
Jiang
Wen-tao
WT
Cai
Jin-zhen
JZ
Hou
Jian-cun
JC
Wei
Lin
L
Zhang
Hai-ming
HM
Wang
Jin-shan
JS
Shen
Zhong-yang
ZY
D000328:Adult; D046148:Donor Selection; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D012189:Retrospective Studies; D055815:Young Adult