Symmetry breaking in plants: molecular mechanisms regulating asymmetric cell divisions in Arabidopsis.
Asymmetric cell division generates cell types with different specialized functions or fates. This type of division is critical to the overall cellular organization and development of many multicellular organisms. In plants, regulated asymmetric cell divisions are of particular importance because cell migration does not occur. The influence of extrinsic cues on asymmetric cell division in plants is well documented. Recently, candidate intrinsic factors have been identified and links between intrinsic and extrinsic components are beginning to be elucidated. A novel mechanism in breaking symmetry was revealed that involves the movement of typically intrinsic factors between plant cells. As we learn more about the regulation of asymmetric cell divisions in plants, we can begin to reflect on the similarities and differences between the strategies used by plants and animals. Focusing on the underlying molecular mechanisms, this article describes three selected cases of symmetry-breaking events in the model plant Arabidopsis thaliana. These examples occur in early embryogenesis, stomatal development, and ground tissue formation in the root.
Petricka
Jalean J
JJ
Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina 27708, USA.
Van Norman
Jaimie M
JM
Benfey
Philip N
PN
D017360:Arabidopsis / Q000196:embryology / Q000378:metabolism / Q000502:physiology*; D002455:Cell Division; D018398:Homeodomain Proteins / Q000378:metabolism; D007210:Indoleacetic Acids / Q000378:metabolism; D008954:Models, Biological; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000378:metabolism*; D018517:Plant Roots / Q000378:metabolism; D054046:Plant Stomata; D015398:Signal Transduction
D018398:Homeodomain Proteins; D007210:Indoleacetic Acids; D010940:Plant Proteins