The use of optical coherence tomography in neurology.
Optical coherence tomography (OCT) is a noninvasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. OCT allows direct visualization and measurement of the topography of the optic nerve head and retinal nerve fiber layer thickness in the peripapillary and macular regions with micron-scale resolution. These measurements are of particular interest in optic neuropathies and in numerous neurologic disorders in which there is axonal loss, such as multiple sclerosis. This article provides a detailed overview of OCT and its potential applications in neurology.
Lamirel
Cédric
C
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Newman
Nancy
N
Biousse
Valéerie
V
D003936:Diagnosis, Computer-Assisted; D006801:Humans; D009412:Nerve Fibers / Q000473:pathology; D009462:Neurology; D009885:Ophthalmology; D009898:Optic Disk / Q000473:pathology; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D041623:Tomography, Optical Coherence / Q000379:methods*