title: Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men.
abstract: OBJECTIVE
  Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men.
  
  
  METHODS
  Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL.
  
  
  RESULTS
  Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean+/-SEM: 37.6+/-4.7 vs. 51.0+/-6.6 ng/mL, respectively, p= 0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks.
  
  
  CONCLUSIONS
  This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.
authors.affiliation: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Division of Sports Medicine, Ibarak 305-8574i, Japan. miyashita@stat.taiiku.tsukuba.ac.jp
authors.forename: Masashi
authors.initials: M
authors.lastname: Miyashita
authors.forename: Miki
authors.initials: M
authors.lastname: Eto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sasai
authors.forename: Takehiko
authors.initials: T
authors.lastname: Tsujimoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nomata
authors.forename: Kiyoji
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000925:Anticoagulants; D015930:Diet Records; D015444:Exercise / Q000502:physiology*; D006493:Heparin; D006801:Humans; D007590:Jogging / Q000502:physiology*; D050356:Lipid Metabolism / Q000502:physiology; D008071:Lipoprotein Lipase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000503:physiopathology*; D050177:Overweight / Q000097:blood / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000502:physiology; D014280:Triglycerides / Q000097:blood; D016138:Walking / Q000502:physiology
chemical_list: D000925:Anticoagulants; D014280:Triglycerides; D006493:Heparin; D008071:Lipoprotein Lipase