title: Celiac disease and Hp infection association in Iran.
abstract: BACKGROUND
  we assessed the prevalence, the related symptoms, and the endoscopic and histologic gastric features of celiac disease (CD) in patients with Helicobacter pylori (Hp).
  
  
  METHODS
  450 dyspeptic patients were studied. Biopsies of gastric antrum and duodenum, CD serology, and total IgA were obtained. Histological findings were scored with the Marsh-Rostami criteria.
  
  
  RESULTS
  411 (91.3%) patients were Hp positive. Duodenal histology was normal in 385 (85.6%) patients, 124 (27.5%) had duodenitis and 28 (6.2%) showed duodenal abnormalities (Marsh I-IIIc). Twenty three/28 (82.1%) patients with malabsorption pattern were also Hp positive. Serological analysis: 12 of 31 (38.7%) positive patients had abnormal histology (Marsh I,-IIIc). Nine out 450 patients were IgA deficient; none of them was serologically positive for CD.
  
  
  CONCLUSIONS
  although a high prevalence of Hp infection was found in this study, the relationship between Hp infection and CD was similar to that reported in other geographic areas.
authors.affiliation: Research Center of Gastroenterology and Liver Disease. Shaheed Beheshti University, M.C. Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Rostami-Nejad
authors.forename: V
authors.initials: V
authors.lastname: Villanacci
authors.forename: R
authors.initials: R
authors.lastname: Mashayakhi
authors.forename: M
authors.initials: M
authors.lastname: Molaei
authors.forename: G
authors.initials: G
authors.lastname: Bassotti
authors.forename: H
authors.initials: H
authors.lastname: Zojaji
authors.forename: D
authors.initials: D
authors.lastname: Mirstatari
authors.forename: K
authors.initials: K
authors.lastname: Rostami
authors.forename: M R
authors.initials: MR
authors.lastname: Zali
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D004386:Duodenum / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D016480:Helicobacter pylori; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012699:Serology; D013270:Stomach / Q000473:pathology