[Does collagen microunfolding stimulate the fibril formation?].
The data on the effect of temperature on the kinetics of collagen fibril formation at physiological pH values and ionic strength in the temperature range 26-39 degrees C have been analyzed. The temperature of 35 degrees C optimal for collagen fibril formation has been defined as the turning point for halfmaximal turbidity and collagen molecule microunfolding values, which corresponds to the temperature of the first transition on the heat absorption curve. The temperature range (32-35 degrees C) in which collagen microunfolding stimulates fibril formation has been determined.
Nikolaeva
T I
TI
Kuznetsova
S M
SM
Tiktopulo
E I
EI
D000818:Animals; D024022:Fibrillar Collagens / Q000737:chemistry*; D007700:Kinetics; D017510:Protein Folding; D013552:Swine; D013696:Temperature
D024022:Fibrillar Collagens