New biologically active compounds from Kenyan propolis.
From propolis samples from Kenya, two new arylnaphtalene lignans were isolated, tetrahydrojusticidin B 1 and 6-methoxydiphyllin 2, along with four known phenolic compounds 5-8, found for the first time in propolis. The structures of the compounds were elucidated based on their spectral properties. The geranylstilbenes 7 and 8 demonstrated antibacterial activity against S. aureus, and the geranylflavon macarangin 6 possessed antiradical activity against DPPH radicals.
Petrova
Assya
A
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad G Bonchev str Bl 9, 1113 Sofia, Bulgaria.
Popova
Milena
M
Kuzmanova
Christina
C
Tsvetkova
Iva
I
Naydenski
Hristo
H
Muli
Eliud
E
Bankova
Vassya
V
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000302:isolation & purification*; D007630:Kenya; D017705:Lignans / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009281:Naphthalenes / Q000302:isolation & purification; D011429:Propolis / Q000737:chemistry*
C553379:6-methoxydiphyllin; D000900:Anti-Bacterial Agents; D016166:Free Radical Scavengers; D017705:Lignans; D009281:Naphthalenes; C553378:tetrahydrojusticidin B; D011429:Propolis