An electrochemical peptide-based biosensing platform for HIV detection.
We have fabricated a potentially generalizable electrochemical peptide-based (E-PB) sensor for the detection of HIV anti-p24 antibodies. The E-PB sensor is sensitive, specific and fares well even when challenged in a realistically complex medium such as human urine proxy.
Gerasimov
Jennifer Y
JY
Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, USA.
Lai
Rebecca Y
RY
D000595:Amino Acid Sequence; D015374:Biosensing Techniques / Q000379:methods; D004563:Electrochemistry / Q000379:methods*; D000939:Epitopes / Q000737:chemistry / Q000276:immunology; D015483:HIV Antibodies / Q000276:immunology / Q000652:urine*; D016655:HIV Core Protein p24 / Q000276:immunology*; D015658:HIV Infections / Q000175:diagnosis*; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D010455:Peptides / Q000737:chemistry / Q000276:immunology*; D012680:Sensitivity and Specificity
D000939:Epitopes; D015483:HIV Antibodies; D016655:HIV Core Protein p24; D010455:Peptides