title: Invasive pneumococcal disease following treatment for choroid plexus carcinoma.
abstract: BACKGROUND
  A 13-month-old child was treated for choroid plexus carcinoma with partial embolisation, complete surgical excision and chemotherapy. The patient's course was complicated by the presence of chronic bilateral subdural collections.
  
  
  METHODS
  Four months from completing treatment, the child presented with an empyema in the subdural space caused by Streptococcus pneumoniae subtype 6A.
  
  
  CONCLUSIONS
  The case highlights a number of questions about pneumococcal immunisation after standard chemotherapy. Evidence-based guidelines are required urgently to direct best practice.
authors.affiliation: Department of Haematology/Oncology, Great Ormond Street Hospital, London WC1N 3JH, UK.
authors.forename: Mette
authors.initials: M
authors.lastname: Jorgensen
authors.forename: Jessica
authors.initials: J
authors.lastname: Bate
authors.forename: Sylvia
authors.initials: S
authors.lastname: Gatscher
authors.forename: Julia C
authors.initials: JC
authors.lastname: Chisholm
mesh_terms: D016545:Choroid Plexus Neoplasms / Q000188:drug therapy*; D013354:Empyema, Subdural; D006801:Humans; D007114:Immunization; D007223:Infant; D011008:Pneumococcal Infections / Q000175:diagnosis*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*