Importance of intraoperative parathyroid hormone measurement in the diagnosis of parathyroid lipoadenoma.
BACKGROUND
Parathyroid lipoadenoma is an uncommon tumor that may be difficult to diagnose on intraoperative frozen section. Intraoperative parathyroid hormone (PTH) measurement is useful in assessing the adequacy of parathyroidectomy. This case demonstrates the value of intraoperative PTH measurement in recognizing a parathyroid lipoadenoma.


RESULTS
A case of a 62-year-old woman with primary hyperparathyroidism in which intraoperative PTH measurement helped confirm the diagnosis of parathyroid lipoadenoma is presented.


CONCLUSIONS
In patients with primary hyperparathyroidism, a significant decrease in intraoperative PTH confirms that an enlarged parathyroid with normal to low cellularity containing abundant fat is a lipoadenoma and that further exploration is not necessary.
Lee
Ann Y
AY
Division of Endocrine Surgery, Department of Surgery, New York University Langone Medical Center, New York, NY, USA.
Wang
Beverly Y
BY
Heller
Keith S
KS
D000236:Adenoma / Q000097:blood / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D007150:Immunohistochemistry; D008067:Lipoma / Q000097:blood* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D009367:Neoplasm Staging; D010281:Parathyroid Hormone / Q000097:blood*; D010282:Parathyroid Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D016105:Parathyroidectomy / Q000379:methods*; D035583:Rare Diseases; D018570:Risk Assessment; D016896:Treatment Outcome
D010281:Parathyroid Hormone