Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia.
Phytochemical investigation of the methanol extract of Tinospora cordifolia aerial parts led to the isolation of four new and seven known compounds. The structures of two new aporphine alkaloids, N-formylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside A, 1) and N-acetylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside B, 2), a new clerodane diterpene, tinoscorside C (3), and a new phenylpropanoid, sinapyl 4-O-beta-D-apiofuranosyl-(1-->6)-O-beta-D-glucopyranoside (tinoscorside D, 6) were determined by extensive spectroscopic methods including FTICR-MS and 1D and 2D NMR.
Phan
Van Kiem
VK
Laboratory of Organic Chemistry, Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam. phankiem@vast.ac.vn
Chau
Van Minh
VM
Nguyen
Tien Dat
TD
La
Van Kinh
VK
Dan
Thuy Hang
TH
Nguyen
Hoai Nam
HN
Nguyen
Xuan Cuong
XC
Hoang
Thanh Huong
TH
Trinh
Van Lau
VL
D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000302:isolation & purification; D015394:Molecular Structure; D010666:Phenylpropionates / Q000302:isolation & purification; D031610:Tinospora / Q000737:chemistry*
D001060:Aporphines; D045785:Diterpenes, Clerodane; D005960:Glucosides; D010666:Phenylpropionates; C028305:syringin