title: Increased oxidative stress in patients with pseudoexfoliation syndrome.
abstract: OBJECTIVE
  The objective of this study was to investigate the antioxidant/oxidant status of serum in patients with pseudoexfoliation syndrome (PEX).
  
  
  METHODS
  Forty-seven patients with PEX and 32 healthy controls were included in the study. Serum total antioxidant capacity (TAC) and total oxidant status (TOS) levels were determined by using a novel automated method.
  
  
  RESULTS
  A significant increase in serum TOS (p < 0.001) and a significant decrease in serum TAC (p < 0.0001) were observed in PEX patients compared to control subjects.
  
  
  CONCLUSIONS
  TAC decreases while the oxidative stress increases in PEX.
authors.affiliation: Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. tongabay@superonline.com
authors.forename: Tongabay
authors.initials: T
authors.lastname: Cumurcu
authors.forename: Abuzer
authors.initials: A
authors.lastname: Gunduz
authors.forename: Huseyin
authors.initials: H
authors.lastname: Ozyurt
authors.forename: Hatun
authors.initials: H
authors.lastname: Nurcin
authors.forename: Omer
authors.initials: O
authors.lastname: Atis
authors.forename: Mucahit
authors.initials: M
authors.lastname: Egri
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood*; D016022:Case-Control Studies; D017889:Exfoliation Syndrome / Q000097:blood*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D016877:Oxidants / Q000097:blood*; D018384:Oxidative Stress; D011446:Prospective Studies; D014065:Tonometry, Ocular
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D016877:Oxidants