Tumor self-seeding: bidirectional flow of tumor cells.
Circulating tumor cells are responsible for seeding metastatic growth at distant sites. Kim et al. (2009) now discover that circulating tumor cells can reinfiltrate tumors at their primary organs and promote tumor progression.
Leung
Cheuk T
CT
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Brugge
Joan S
JS
D000818:Animals; D018450:Disease Progression; D006801:Humans; D009366:Neoplasm Seeding; D009369:Neoplasms / Q000473:pathology* / Q000503:physiopathology; D009360:Neoplastic Cells, Circulating / Q000473:pathology*