Extramedullary relapse of acute lymphoblastic leukemia in breast: a rare presentation.
Unusual sites of relapses following allogenic hematopoietic stem cell transplantation (HSCT) for acute lymphoblastic leukemia (ALL) are rarely reported. Our report describes a thirty-two-year old female, who developed extramedullary (EM) breast relapse after allogenic HSCT for pre B cell Philadelphia chromosome negative ALL. She had no evidence of leukemia in her marrow demonstrating 100% full donor chimerism, while she had ALL relapse in her breast.
Thanka
J
J
Department of Pathology, Sri Ramachandra University, Porur, Chennai 600 116, India.
Krishnarathinam
K
K
Rajendiran
S
S
D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology* / Q000556:secondary*; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006651:Histocytochemistry; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy; D012008:Recurrence