Role of left ventricular twist mechanics in the assessment of cardiac dyssynchrony in heart failure.
The authors discuss an incremental value of assessing left ventricular (LV) twist mechanics in patients with heart failure (HF) and its potential usefulness in characterizing response to cardiac resynchronization therapy (CRT) and reversal of LV remodeling at 6 months follow-up. They also underscore a critical relationship between LV lead position and changes in LV twist after CRT, and suggest that the reversal of LV remodeling in HF patients following CRT primarily results from restoration of the global sequence of LV twist mechanics.
Bertini
Matteo
M
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Sengupta
Partho P
PP
Nucifora
Gaetano
G
Delgado
Victoria
V
Ng
Arnold C T
AC
Marsan
Nina Ajmone
NA
Shanks
Miriam
M
van Bommel
Rutger R J
RJ
Schalij
Martin J
MJ
Narula
Jagat
J
Bax
Jeroen J
JJ
D002304:Cardiac Pacing, Artificial; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D013997:Time Factors; D014102:Torsion Abnormality / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D054159:Torsion, Mechanical; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling