'Primary cutaneous mucormycosis during induction chemotherapy in a child with acute lymphoblastic leukemia'.
We report a child with acute lymphoblastic leukemia who developed primary cutaneous mucormycosis at the site of lumbar puncture during induction chemotherapy. Though high mortality rates are reported with invasive mucormycosis, prompt biopsy, early identification and antifungal therapy using a combination regime of amphotericin-B and rifampicin along with extensive surgical debridement led to complete cure of the lesions in the index case.
Sankar
Jhuma
J
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Arun
Sasi
S
Sankar
Mari Jeeva
MJ
Seth
Rachna
R
Thavraj
Vasantha
V
Kabra
Sushil Kumar
SK
Vasantha
M
M
D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000139:chemically induced* / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012871:Skin Diseases / Q000139:chemically induced* / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D000666:Amphotericin B