Comparison of whole body scintigraphy with Tc-99m-methoxyisobutylisonitrile and iodine-131 NA in patients with differentiated thyroid cancer.
In this study we compared whole body scintigraphy with Tc-99m-methoxyisobutylisonitrile (MIBI) and Iodine-131 NA (131I) for detection of residual and/or metastatic disease in well differentiated thyroid carcinoma.


METHODS
MIBI and I-131 scans were obtained in 60 patients. TSH measurements were done in all the patients prior to scintigraphy.


RESULTS
Out of 60 patients, for whom both I-131 and MIBI scans were done, I-131 scans were positive in 59 (98.3%) patients, whereas MIBI scans were positive in only 17 (27%) patients. There was only one patient in which I-131 scan was negative and MIBI scan was positive.


CONCLUSIONS
I-131 scintigraphy still remains the best way to successfully detect residual/metastatic disease in differentiated thyroid carcinoma.
Al Saleh
K
K
Department of Radiation Oncology, Kuwait Cancer Control Centre, Ministry of Public Health, Kuwait.
Safwat
R
R
Al-Shammeri
I
I
Abdul Naseer
M
M
Hooda
H
H
Al-Mohannadi
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013438:Sulfhydryl Compounds; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D055815:Young Adult
D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013438:Sulfhydryl Compounds; C013274:technetium Tc 99m mercaptoisobutyric acid