title: Integrated acoustic and magnetic separation in microfluidic channels.
abstract: With a growing number of cell-based biotechnological applications, there is a need for particle separation systems capable of multiparameter separations at high purity and throughput, beyond what is presently offered by traditional methods including fluorescence activated cell sorting and column-based magnetic separation. Toward this aim, we report on the integration of microfluidic acoustic and magnetic separation in a monolithic device for multiparameter particle separation. Using our device, we demonstrate high-purity separation of a multicomponent particle mixture at a throughput of up to 10(8) particleshr.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Adams
authors.forename: Patrick
authors.initials: P
authors.lastname: Thévoz
authors.forename: Henrik
authors.initials: H
authors.lastname: Bruus
authors.forename: H Tom
authors.initials: HT
authors.lastname: Soh