Parameters for coronary plaque vulnerability assessed with multidetector computed tomography and intracoronary ultrasound correlation.
In the absence of a fixed relationship between plaque vulnerability and flow-limiting stenosis, alternative morphological expressions exist that could predict the liability of coronary lesions to rapidly progress or rupture, causing acute coronary syndromes. Modern multidetector computed tomography technology is capable of noninvasively detecting lesion location, attenuation, remodeling and calcification pattern, which may be considered as surrogate morphological markers of vulnerability and could contribute to increase the prognostic value of individual coronary plaque burden.
Pugliese
Francesca
F
Department of Radiology, The Netherlands Azienda Ospedaliero-Universitaria di Parma, Non-Invasive Cardiovascular Imaging, Piastra Tecnica, Piano 0, Via Gramsci 14, 43100 Parma, Italy.
Meijboom
Willem B
WB
Ligthart
Jurgen
J
La Grutta
Ludovico
L
Vourvouri
Eleni C
EC
Rodriguez-Granillo
Gaston
G
Mollet
Nico R
NR
Krestin
Gabriel P
GP
de Feyter
Pim J
PJ
Cademartiri
Filippo
F
D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D012421:Rupture; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional