title: Novel bifunctional sulfonamides catalyze an enantioselective conjugate addition.
abstract: A new bifunctional organocatalyst with a novel structural and functional motif has been developed. This bifunctional sulfonamide organocatalyst was used in the conjugate addition of 1,3-dicarbonyl compounds (13) to β-nitrostyrenes (12). Yields up to 91% and enantiomeric excesses up to 79% were obtained in this reaction. This catalyst activates both 13 via its basic moiety and 12 through hydrogen bonding.
authors.affiliation: Department of Chemistry, Brooklyn College and the City University of New York, 2900 Bedford Avenue, Brooklyn, NY 11210, USA.
authors.forename: Patrick G
authors.initials: PG
authors.lastname: McGarraugh
authors.forename: Stacey E
authors.initials: SE
authors.lastname: Brenner