title: [The function of histone chaperones during development].
abstract: Histone chaperones may participate the decondensation and assembly of chromatins, thus regulate gene expression. They play important roles in almost all developmental processes, such as gametogenesis, fertilization, embryogenesis, growth and senescence. In this review, we used well studied examples to illustrate various functions of histone chaperones during developmental processes. Focus is given to nucleoplasmin, CAF-1, HIRA, ASF1/CIA, and NAP1.
authors.affiliation: Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Science, Huazhong Normal University, Wuhan 430079, China.
authors.forename: Zhan-Ke
authors.initials: ZK
authors.lastname: Zhao
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Wang
mesh_terms: D000818:Animals; D056890:Eukaryota / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D056488:Histone Chaperones / Q000235:genetics / Q000378:metabolism*; D006801:Humans
chemical_list: D056488:Histone Chaperones