Subsequent memory-dependent EEG theta correlates to parahippocampal blood oxygenation level-dependent response.
The 4-12 Hz (theta rhythm)-dependent neural dynamics play a fundamental role in the memory formation of the rat hippocampus. Although the power of human scalp electroencephalography theta (EEG theta) is known to be associated with a hippocampus-dependent memory encoding, it remains unclear whether the human hippocampus uses theta rhythm. In this study, we aim to identify the scalp EEG theta-related neural regions during memory encoding by using a simultaneous EEG-functional magnetic resonance imaging recording. We showed that the parahippocampal and the medial frontal and posterior regions were significantly correlated to subsequent memory-dependent EEG theta power. This evidence suggests that the human parahippocampal region and associated structures use theta rhythm during hippocampal memory encoding as in rodents.
Sato
Naoyuki
N
Department of Complex Systems, School of Systems Information Science, Future University-Hakodate, Hakodate, Hokkaido 041-8655, Japan. satonao@fun.ac.jp
Ozaki
Takashi J
TJ
Someya
Yoshiaki
Y
Anami
Kimitaka
K
Ogawa
Seiji
S
Mizuhara
Hiroaki
H
Yamaguchi
Yoko
Y
D000328:Adult; D001931:Brain Mapping / Q000379:methods; D005260:Female; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D013826:Theta Rhythm