title: Surgical treatments for infective endocarditis involving valve annulus.
abstract: OBJECTIVE
  The early and late results of infective endocarditis (IE) with annular involvement were studied by focusing on surgical findings and operative procedures.
  
  
  METHODS
  Fifteen adult patients with a mean age of 56 years were reviewed. Eight had native valve endocarditis (NVE), and 7 had prosthetic valve endocarditis (PVE). The diseased valve was mitral in 6 patients, aortic in 8, and mitral plus aortic in 1. Twelve patients were operated on during the active phase of IE. Enterococcus, Staphyrococcus, Streptococcus, and Stenotrophomonaus Maltophilia were predominant in bacterial examination. The mean follow-up period was 37 months.
  
  
  RESULTS
  Active vegetation was observed in 63% of total patients. In NVE patients, valve replacement was performed in all 8 after complete debridement and annular patch reconstruction. One patient with hemodialysis died of heart failure. In PVE patients, valve deficiency was observed in all and active perivalvular abscess in 4. Conventional valve replacement was performed in 4 patients, and 3 of them died after surgery. Three patients who underwent aortic root translocation or Ross procedure survived. The hospital mortality of NVE and PVE surgery was 3% and 43%, respectively. There were no significant correlations between operative results and perioperative factors. During the follow-up period, late recurrent endocarditis did not occur, and one patient died of noncardiac diseases.
  
  
  CONCLUSIONS
  For NVE, good operative results were obtained after complete resection of infected valve annulus and valve replacement. For PVE, new surgical treatments, such as the translocation method or Ross procedure, should be induced for further improvement of surgical results.
authors.affiliation: Department of Surgery, Cardiovascular Division, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Akio
authors.initials: A
authors.lastname: Kawasaki
authors.forename: Kazuo
authors.initials: K
authors.lastname: Neya
authors.forename: Keiko
authors.initials: K
authors.lastname: Abe
authors.forename: Haruo
authors.initials: H
authors.lastname: Suzuki
authors.forename: Satoko
authors.initials: S
authors.lastname: Koizumi
authors.forename: Hajime
authors.initials: H
authors.lastname: Shibuya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Horikawa
authors.forename: Keisuke
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000382:microbiology / Q000601:surgery*; D016009:Chi-Square Distribution; D003646:Debridement; D004696:Endocarditis / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D005260:Female; D006349:Heart Valve Diseases / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000382:microbiology / Q000601:surgery*; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome