title: A synthesis of oligomeric alpha-hydroxy phenylphosphinates and a study of the conformational preferences of the dimers.
abstract: A general method for the synthesis of a novel class of oligomers, comprising alpha-hydroxy phenylphosphinic acid building blocks, is reported. A series of dimeric alpha-hydroxy phenylphosphinates are analyzed by a combination of NMR spectroscopy, X-ray crystallography and computational methods.
authors.affiliation: Institute of Cancer Therapeutics, Thumbling Hill Street, Bradford, UK BD7 1DP. k.afarinkia@bradford.ac.uk
authors.forename: Kamyar
authors.initials: K
authors.lastname: Afarinkia
authors.forename: Martin
authors.initials: M
authors.lastname: Royappa
authors.forename: Ian J
authors.initials: IJ
authors.lastname: Scowen
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Steed
authors.forename: Hiu-Wan
authors.initials: HW
authors.lastname: Yu
mesh_terms: D002244:Carbon / Q000737:chemistry; D019281:Dimerization; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010758:Phosphorus / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*; D017510:Protein Folding; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D009943:Organophosphorus Compounds; D011108:Polymers; D010758:Phosphorus; D002244:Carbon; C023604:phenylphosphonic acid