title: Arterial pressure optimization in the treatment of septic shock: a complex puzzle.
abstract: Arterial pressure optimization in septic shock is a critical, yet poorly understood component of resuscitation. New data suggest that, during the routine management of patients with severe sepsis, there is no association between mean arterial pressure achieved and outcome as long as the mean arterial pressure is maintained at or above 70 mmHg. Although these data add important new evidence to our understanding of arterial pressure management, there are still many unanswered questions upon which future investigations should focus.
authors.affiliation: Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA.
authors.forename: Alan E
authors.initials: AE
authors.lastname: Jones
authors.forename: Stephen
authors.initials: S
authors.lastname: Trzeciak
authors.forename: R Phillip
authors.initials: RP
authors.lastname: Dellinger
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D006801:Humans; D012772:Shock, Septic / Q000401:mortality*