Fetal radiation exposure and moyamoya disease.
Moyamoya disease is a progressive occlusive disease of the cerebral vasculature with particular involvement of the circle of Willis. We present the first reported patient with moyamoya disease possibly due to radiation exposure during fetal development. A 10-year-old male, whose mother had undergone radiotherapy when pregnant, presented with moyamoya disease. The relevant literature is discussed.
Kansal
R
R
Department of Neurosurgery, King Edward Memorial Hospital, Seth G.S. Medical College, Acharya Donde Marg, Parel, Mumbai 400 012, India.
Mahore
A
A
Nadkarni
T
T
Goel
A
A
D020520:Brain Infarction / Q000209:etiology; D002648:Child; D017023:Coronary Angiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000209:etiology*; D010291:Paresis / Q000150:complications; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011878:Radiotherapy / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed / Q000379:methods