title: Rapid radiation dose assessment for radiological public health emergencies: roles of NIAID and BARDA.
abstract: A large-scale radiological incident would result in an immediate critical need to assess the radiation doses received by thousands of individuals to allow for prompt triage and appropriate medical treatment. Measuring absorbed doses of ionizing radiation will require a system architecture or a system of platforms that contains diverse, integrated diagnostic and dosimetric tools that are accurate and precise. For large-scale incidents, rapidity and ease of screening are essential. The National Institute of Allergy and Infectious Diseases of the National Institutes of Health is the focal point within the Department of Health and Human Services (HHS) for basic research and development of medical countermeasures for radiation injuries. The Biomedical Advanced Research and Development Authority within the HHS Office of the Assistant Secretary for Preparedness and Response coordinates and administers programs for the advanced development and acquisition of emergency medical countermeasures for the Strategic National Stockpile. Using a combination of funding mechanisms, including funds authorized by the Project BioShield Act of 2004 and those authorized by the Pandemic and All-Hazards Preparedness Act of 2006, HHS is enhancing the nation's preparedness by supporting the radiation dose assessment capabilities that will ensure effective and appropriate use of medical countermeasures in the aftermath of a radiological or nuclear incident.
authors.affiliation: Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, Department of Health and Human Services, Washington, DC 20201, USA. marcy.grace@hhs.gov
authors.forename: Marcy B
authors.initials: MB
authors.lastname: Grace
authors.forename: Brian R
authors.initials: BR
authors.lastname: Moyer
authors.forename: Joanna
authors.initials: J
authors.lastname: Prasher
authors.forename: Kenneth D
authors.initials: KD
authors.lastname: Cliffer
authors.forename: Narayani
authors.initials: N
authors.lastname: Ramakrishnan
authors.forename: Joseph
authors.initials: J
authors.lastname: Kaminski
authors.forename: C Norman
authors.initials: CN
authors.lastname: Coleman
authors.forename: Ronald G
authors.initials: RG
authors.lastname: Manning
authors.forename: Bert W
authors.initials: BW
authors.lastname: Maidment
authors.forename: Richard
authors.initials: R
authors.lastname: Hatchett
mesh_terms: D001681:Biological Assay / Q000379:methods*; D001822:Body Burden; D018788:Radioactive Hazard Release; D011874:Radiometry / Q000379:methods*; D018570:Risk Assessment / Q000379:methods; D014218:Triage / Q000379:methods* / Q000458:organization & administration; D014481:United States