title: Copper(I)-catalyzed asymmetric monoborylation of 1,3-dienes: synthesis of enantioenriched cyclic homoallyl- and allylboronates.
abstract: Copper(I)-catalyzed asymmetric monoborylation of 1,3-dienes has been developed. We describe the production of either optically active homoallyl- or allylboronates with high regio- and enantioselectivity (88-97% ee) through monoborylation of 1,3-dienes. The reaction with 1,3-cyclohexadiene derivatives afforded the corresponding enantioenriched homoallyboronates. By simply changing the reaction conditions, a drastic change of product preference between homoallyl- and allylboronates was found in the reaction of 1,3-cyclopentadiene and 1,3-cycloheptadiene.
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Chongmin
authors.initials: C
authors.lastname: Zhong
authors.forename: Masaya
authors.initials: M
authors.lastname: Sawamura
authors.forename: Hajime
authors.initials: H
authors.lastname: Ito