Analgesic and diuretic properties of alpha-santalone from Polygonum flaccidum.
Polygonum flaccidum Meissn. is an annual herb, native to Bangladesh, and well known for its analgesic, anti-inflammatory, diuretic, purgative and insecticidal properties, and also for its use against snake-bites. The analgesic and the diuretic properties of alpha-santalone (1), isolated from the aerial parts of Polygonum flaccidum, were assessed by the acetic-acid-induced writhing method and the Lipschitz test, respectively. Complete (1)H and (13)C NMR data of 1 are also presented.
Mazid
Md Abdul
MA
Phytopharmacology Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Datta
Bidyut K
BK
Nahar
Lutfun
L
Rashid
Md Abdur
MA
Bachar
Sitesh C
SC
Bashar
S A M Khairul
SA
Sarker
Satyajit D
SD
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001952:Bridged-Ring Compounds / Q000302:isolation & purification / Q000494:pharmacology*; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology*; D028502:Polygonum / Q000737:chemistry*; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
D000700:Analgesics; D001952:Bridged-Ring Compounds; D004232:Diuretics; D010936:Plant Extracts; D012717:Sesquiterpenes; C551894:alpha-santalone