title: [Prognostic factors and comorbidity impact upon the frontolateral laryngectomy].
abstract: OBJECTIVE
  To evaluate the survival rates, comorbidity impact, complications, and treatment failure facts.
  
  
  METHODS
  38 patients clinically staged as T1b / T2N0M0 glottic tumors were analyzed. They underwent frontolateral laryngectomy with reconstruction, from January, 1995 to December, 2006. The oncological outcome, comorbidity (through the Adult Comorbidity Evaluation -27 ACE-27 scale) and complications were studied and correlated to the demographic data and tumor characteristics.
  
  
  RESULTS
  Eight patients presented local recurrence being surgically salvaged. Complications were not observed in 33 patients. There was no significant difference on the global and free of disease 5-year survival regarding the diverse comorbidity categories. Only the pathological margins spread of the tumor presented significant difference on the global (p=0.0033) and free of disease survival (p<0.0001).
  
  
  CONCLUSIONS
  The 5-year global survival was 67.6% whereas the free of disease survival was 73.7%; the comorbidity did not represent independent prognostic factor; the postoperative complications rate was 13.2%; and only the pathological margin spread showed significant difference on the global and free of disease survival rates.
authors.affiliation: Livre Docente pela Fundação Lusíada, Santos, SP-BR. dedivitis.hns@uol.com.br
authors.forename: Rogério Aparecido
authors.initials: RA
authors.lastname: Dedivitis
authors.forename: Jozías
authors.initials: J
authors.lastname: de Andrade-Sobrinho
authors.forename: Mario Augusto Ferrari
authors.initials: MA
authors.lastname: de Castro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects* / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis