title: [Pathophysiology and treatment of paroxysmal nocturnal hemoglobinuria (PNH)--recent advances].
authors.forename: Akiko
authors.initials: A
authors.lastname: Shichishima
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Shichishima
mesh_terms: D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D001855:Bone Marrow Diseases / Q000209:etiology; D002986:Clinical Trials as Topic; D003165:Complement System Proteins; D025743:HMGA2 Protein / Q000737:chemistry / Q000235:genetics; D006457:Hemoglobinuria, Paroxysmal / Q000188:drug therapy* / Q000209:etiology*; D006461:Hemolysis; D006801:Humans; D008969:Molecular Sequence Data; D020246:Venous Thrombosis / Q000209:etiology
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D025743:HMGA2 Protein; D003165:Complement System Proteins; C481642:eculizumab