title: Copper-promoted coupling of vinyl boronates and alcohols: a mild synthesis of allyl vinyl ethers.
abstract: A copper-promoted coupling of vinyl pinacol boronate esters and alcohols for the synthesis of enol ethers is reported. The reaction occurs in 50-99% yield and is compatible with a variety of functional groups. Cupric acetate is the copper source, and triethylamine buffer is used to prevent protodeboration; the reaction occurs at room temperature. In addition to excellent chemoselectivity, the reaction is stereospecific.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA.
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Shade
authors.forename: Alan M
authors.initials: AM
authors.lastname: Hyde
authors.forename: John-Carl
authors.initials: JC
authors.lastname: Olsen
authors.forename: Craig A
authors.initials: CA
authors.lastname: Merlic