title: Fracture of zotarolimus-eluting stent after implantation.
abstract: Drug-eluting stents were developed and approved for the reduction of in-stent restenosis. However, restenosis still occurs, and stent fracture is suggested as a cause of restenosis after implantation. Although sirolimus-eluting stents are considered to carry a high risk of fracture, the risk is also present with other drug-eluting stents. Herein, we report the case of a 78-year-old woman who received a zotarolimus-eluting stent for a bifurcation lesion of the left anterior descending coronary artery. Ten months later, she underwent coronary angiography due to angina. The angiogram revealed in-stent restenosis, with a grade IV stent fracture. After percutaneous coronary angioplasty, the patient's clinical symptoms improved.
authors.affiliation: Department of Cardiology, Chi-Mei Medical Center, Yong-Kang City, Tainan County 710, Taiwan.
authors.forename: Meng-Chieh
authors.initials: MC
authors.lastname: Wu
authors.forename: Chen-Chuan
authors.initials: CC
authors.lastname: Cheng
authors.forename: Tsuei-Yuan
authors.initials: TY
authors.lastname: Huang
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000209:etiology; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D011475:Prosthesis Failure; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; C489443:zotarolimus; D020123:Sirolimus