Calciphylaxis following kidney transplantation: a case report.
BACKGROUND
Calciphylaxis occurring after kidney transplantation is rare and rarely reported. It results in chronic non-healing wounds and is associated with a poor prognosis and is often fatal. We present a case of proximal lower limb calciphylaxis that occurred early after kidney transplantation. The patient had no classic associated risk factors. He had previously had a total parathyroidectomy but had normal serum calcium-phosphate product and parathyroid hormone levels. The clinical outcome of this case was favorable and highlights some fundamental issues relating to management.


METHODS
A 70-year-old British Caucasian man with end-stage renal failure secondary to IgA nephropathy presented six months post kidney transplantation with cutaneous calciphylaxis lesions involving the medial aspect of the thigh bilaterally.


CONCLUSIONS
To the best of our knowledge, this is the first reported case of rapid onset cutaneous calciphylaxis occurring soon after kidney transplantation that was associated with a favorable outcome. Cutaneous calciphylaxis lesions should be promptly managed with meticulous wound care, antimicrobial therapy and the correction of calcium-phosphate product where indicated.
Hanvesakul
Rajesh
R
Department of Nephrology, University Hospital Birmingham, Birmingham B15 2TH, UK.
Silva
Michael A
MA
Hejmadi
Rahul
R
Mellor
Steve
S
Ready
Andrew R
AR
Cockwell
Paul
P
Inston
Nicholas
N