Chronic kidney disease and metabolic syndrome in a general Korean population: the Third Korea National Health and Nutrition Examination Survey (KNHANES III) Study.
BACKGROUND
The aims of this study are to examine the prevalence of chronic kidney disease (CKD) with metabolic syndrome (MS) and to investigate the association between CKD and MS after adjustment for socioeconomic position and health behavior factor.


METHODS
The random sample used in this study included 5136 Korean subjects ≥20 years of age. We divided the subjects into two groups based on the presence of MS, for which the criteria described in the NCEP ATP III and International Diabetes Federation were used. Also, CKD was defined as an estimated glomerular filtration rate <60 ml/min/1.73 m(2).


RESULTS
The prevalence of CKD in our study was 6.8%. The age-adjusted prevalence of CKD among those with MS was 9.0% whereas those without MS was 5.6%. After adjusting for age and confounders, people with MS had a 1.77 times greater risk of CKD than those without MS. The adjusted OR increased as the number of MS components increased (P < 0.05).


CONCLUSIONS
The age-adjusted prevalence of CKD in the MS group was higher than that in the non-MS group. After adjustment for socioeconomic position and health behavior factor, MS showed significant association with CKD.
Jang
Shin Yi
SY
Graduate School of Public Health, Seoul National University, 28 Yeongeon-Dong, Jongno-Gu, Seoul, Republic of Korea.
Kim
Il-Ho
IH
Ju
Eun Young
EY
Ahn
Seok Jin
SJ
Kim
Duk-Kyung
DK
Lee
Seung Wook
SW
D000328:Adult; D000368:Aged; D005260:Female; D015438:Health Behavior; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D009749:Nutrition Surveys; D011159:Population Surveillance; D056910:Republic of Korea / Q000453:epidemiology; D018570:Risk Assessment; D012923:Social Class; D055815:Young Adult