Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation.
Novel trityl-nitroxide biradicals were synthesized and exhibited enhanced sensitivity and stability for rapid and simultaneous measurement of redox status and oxygenation by electron paramagnetic resonance spectroscopy.
Liu
Yangping
Y
Center for Biomedical EPR Spectroscopy and Imaging, The Davis Heart and Lung Research Institute, The Division of Cardiovascular Medicine, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Villamena
Frederick A
FA
Rockenbauer
Antal
A
Zweier
Jay L
JL
D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D015335:Molecular Probes / Q000138:chemical synthesis / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D012680:Sensitivity and Specificity
D015335:Molecular Probes; D009589:Nitrogen Oxides; C039900:nitroxyl