[Research progress on schistosome vaccine and prospect of its application in China].
Development of vaccine against schistosomiasis japonica has been incorporated into WHO/TDR and China's main disease control research programs. In recent years,the research on the anti-schistosomiasis vaccine has made significant progress. With the development of proteomics and molecular biology technology, Anti-Schistosoma japonicum vaccine research has been developed to a stage of genetic engineering in our country and DNA vaccines have become the main direction. It reveals new ways to enhance the immunoprotection of Schistosoma japonicum vaccine through screening new candidate antigens, optimizing combination of the mixed/multivalent vaccines, or adjuvant addition.
Wang
Shi-Ping
SP
Xiangya School of Medicine, Central South University, Changsha 410078, China.
Chen
Xiu-Chun
XC
Gao
Dong-Mei
DM
D000818:Animals; D002681:China; D006801:Humans; D012547:Schistosoma / Q000276:immunology*; D012552:Schistosomiasis / Q000276:immunology / Q000517:prevention & control; D019444:Vaccines, DNA
D019444:Vaccines, DNA