[Local recurrence in soft tissue sarcoma: prognostic factors].
OBJECTIVE
To determinate the prognostic factors associated with the local relapse in patients treated for soft tissue sarcoma in extremities.


METHODS
Retrospectively, 30 patients were evaluated after being treated with surgical resection of soft tissue sarcoma located in extremities, with a outcome of 36,5 +/- 12,2 months. The prognostic factors evaluated were: age, sex, location, depth, location in the anatomic compartments, size, tumor previous manipulation, surgical margins, grade of histological malignance, presence of histological necrosis or histological vascular invasion. These factors were correlated with the local relapse of the tumor with a univariated and multivariated analysis with significance when p = 0,05.


RESULTS
Local relapse presented significant correlation in univariated and multivariated analysis with extra-compartimental location (p = 0,001) and with high grade histological malignance (p = 0,001). There was no significant association with age (p = 1,000), sex (p = 1,000), body location (p = 0,544), depth (p = 0,288), size (p = 0,694), surgical margins (p = 0,384), previous manipulation (p = 0,461), necrosis (p = 0,461) or with the presence of vascular invasion (p = 1,000).


CONCLUSIONS
Local relapse presents correlation with extra-compartimental location and with high grade malignancy tumors.
Teixeira
Luiz Eduardo Moreira
LE
Ambulatório de Oncologia Ortopédica do Hospital das Clínicas da Universidade Federal de Minas Gerais - UFMG e no Biocor Instituto, Belo Horizonte, MG, Brasil. luizmteixeira@yahoo.com.br
Araújo
Ivana Duval
ID
de Andrade
Marco Antônio Percope
MA
Gomes
Rogério Andrade
RA
Salles
Paulo Guilherme de Oliveira
PG
Ghedini
Daniel Ferreira
DF
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012509:Sarcoma / Q000453:epidemiology*; D012983:Soft Tissue Neoplasms / Q000453:epidemiology*; D055815:Young Adult