title: [Developments and applications of multidimensional liquid chromatography in proteomics].
abstract: This review summarizes the recent developments of multidimensional liquid chromatography (MDLC) techniques, and their applications in proteomics study, including expression profiling, post-translational modification, quantitative analysis, and so forth. In addition, the prospect and further developments of MDLC are discussed.
authors.affiliation: National Chromatographic R. & A. Center, CAS Key Laboratory of Separation Science for Analytical Chemist Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Guijie
authors.initials: G
authors.lastname: Zhu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liang
authors.forename: Lihua
authors.initials: L
authors.lastname: Zhang
authors.forename: Yukui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D020869:Gene Expression Profiling; D011499:Protein Processing, Post-Translational; D040901:Proteomics