[The running status of Chinese Measles Laboratory Network in 2008].
OBJECTIVE
To evaluate the running status of Measles laboratory network of China (Hong Kong, Macao and Taiwan were excluded) in 2008.


METHODS
To analyze the database of Measles laboratory network surveillance of the year 2008, and the database of serologic and virologic surveillance of National laboratory for Measles in Chinese Centers for Disease Control and Prevention(CCDC), then the indicators of the running of Measles laboratory network of China were analyzed.


RESULTS
1, serologic surveillance: 107,160 Measles sera samples were collected between Feburary and September of 2008, and the collection rate was 77.93%; 53 778 samples were qualified and positive for IgM, the positive percentage was 50.2%. 2, Virologic surveillance: 287 Measles viral isolates were isolated by 18 provincial Measles laboratories in 2008, all were certified as H1a genotype, H1a genotype was still the predominant genotype circulating in China; 29 Rubella viral isolates were isolated by 4 provincial Measles laboratories in 2008, all belonged to 1E genotype. 3, Laboratory quality control: National laboratory for Measles passed the proficiency test and on-site review in 2008; all provincial Measles laboratories passed the sera samples recheck and proficiency test hold by National laboratory for Measles in 2008; Tianjin, Shanxi, Shandong, Zhejiang, Jilin, Hubei, provincial Measles laboratory passed the on-site review by WHO.


CONCLUSIONS
The running status of Chinese Measles laboratory network was good in 2008, and good laboratory quality control system was also set up, methods such as specimens collection, serologic detection, cell culture and viral isolation, etc, were standardized, and applied to Chinese Measles laboratory network, and it provided important scientific basis for eradication Measles in the year of 2012.
Zhang
Yan
Y
World Health Organization Regional Office for the Western Pacific Regional Reference Measles Laboratory, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Xu
Song-Tao
ST
Jiang
Xiao-Hong
XH
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002460:Cell Line; D002681:China / Q000453:epidemiology; D003140:Communicable Disease Control / Q000379:methods*; D005838:Genotype; D006801:Humans; D008457:Measles / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology / Q000821:virology; D008459:Measles virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D011159:Population Surveillance / Q000379:methods*
D000914:Antibodies, Viral