title: Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy.
abstract: Multidetector computed tomography (MDCT) angiography is a reliable technique for assessing pre-operative renal anatomy in living kidney donors. The method has largely evolved into protocols that eliminate dedicated venous phase and instead utilize a combined arterial/venous phase to delineate arterial and venous anatomy simultaneously. Despite adoption of this protocol, there has been no study to assess its accuracy. To assess whether or not MDCT angiography compares favorably to intra-operative findings, 102 donors underwent MDCT angiography without a dedicated venous phase with surgical interpretation of renal anatomy. Anatomical variants included multiple arteries (12%), multiple veins (7%), early arterial bifurcation (13%), late venous confluence (5%), circumaortic renal veins (5%), retroaortic vein (1%), and ureteral duplication (2%). The sensitivity and specificity of multiple arterial anomalies were 100% and 97%, respectively. The sensitivity and specificity of multiple venous anomalies were 92% and 98%, respectively. The most common discrepancy was noted exclusively in the interpretation of right venous anatomy as it pertained to the renal vein/vena cava confluence (3%). MDCT angiography using a combined arterial/venous contrast-enhanced phase provides suitable depiction of renal donor anatomy. Careful consideration should be given when planning a right donor nephrectomy whether the radiographic interpretation is suggestive of a late confluence.
authors.affiliation: Department of Surgery, Section of Organ Transplantation & Immunology, Yale University School of Medicine, New Haven, CT 06410, USA. sanjay.kulkarni@yale.edu
authors.forename: S
authors.initials: S
authors.lastname: Kulkarni
authors.forename: S
authors.initials: S
authors.lastname: Emre
authors.forename: A
authors.initials: A
authors.lastname: Arvelakis
authors.forename: W
authors.initials: W
authors.lastname: Asch
authors.forename: M
authors.initials: M
authors.lastname: Bia
authors.forename: R
authors.initials: R
authors.lastname: Formica
authors.forename: G
authors.initials: G
authors.lastname: Israel
mesh_terms: D000792:Angiography / Q000379:methods*; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000000981:diagnostic imaging*; D019520:Living Donors; D011300:Preoperative Care; D011379:Prognosis; D012077:Renal Artery / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D012082:Renal Veins / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed