New development of 'sono-functional' molecule: binding to DNA by sonication.
'Sono-functional' molecule 1 was prepared and its binding properties to DNA under ultrasonic irradiation were studied by UV spectra. As a result, it was shown that the binding of 1 to DNA was enhanced by ultrasound. Being compared with its precursor 2, it is clear that terminal thiol groups of 1 play an important role in specific binding to DNA.
Sohmiya
Hajime
H
Department of Chemistry, Shiga University of Medical Science, Seta, Otsu, Shiga 520-2192, Japan. sohmiya@belle.shiga-med.ac.jp
Fujita
Mitsue
M
Kimura
Takahide
T
D000609:Aminoacridines / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D000818:Animals; D002417:Cattle; D004247:DNA / Q000378:metabolism*; D012710:Serum Albumin, Bovine / Q000378:metabolism; D013010:Sonication; D013056:Spectrophotometry, Ultraviolet; D014867:Water / Q000737:chemistry
D000609:Aminoacridines; D014867:Water; D012710:Serum Albumin, Bovine; D004247:DNA