Implementation of diabetic foot ulcer classification system for research purposes to predict lower extremity amputation.
BACKGROUND
Patients with diabetic foot ulcers are at a high risk of having both minor or major lower extremity amputations.


OBJECTIVE
To identify the extent of risk factors for major and minor amputations in patients with diabetic foot ulcers.


METHODS
This prospective study was conducted from 2003 to 2005. Using the guidelines for wound classification developed by the International Consensus of the Diabetic Foot, patients were assessed for ischemia, neuropathy, linear measurement of wound diameters, depth of wound, and infection. In addition, end stage renal failure was added as a criterion to assess the association of all these criteria with both toe and lower extremity amputation.


RESULTS
2,321 patients were studied and their mean age was 55 +/- 12 years. Most (83.5%) of the patients presented with foot ulcers (n = 1394). Plantar ulcers were the most common (42.6%) followed by ulcers of the big toe (39%). Some (28.5%) of the patients had different types of amputations: 10% had major lower extreme amputation (MLEA) with 8.7% amputations being below the knee and minor (toe) amputations accounting for 18.5%. The most commonly amputated (9.9%) toe was the first toe.


CONCLUSIONS
The guidelines for wound classification proposed by the International Consensus of the Diabetic Foot are reliable predictive factors and can determine the outcome of diabetic foot management. Significant factors associated with MLEA were ischemia, neuropathy, and end-stage renal disease and those associated with toe amputation were neuropathy, depth of wound, and grade of infection.
Widatalla
Abubakr H
AH
Jabir Abu Eliz Diabetic Center, University of Khartoum. Khartoum, Sudan.
Mahadi
Seif Eidin I
SE
Shawer
Mohamed A
MA
Elsayem
Hagir A
HA
Ahmed
Mohamed E
ME