RNA processing: Redrawing the map of charted territory.
Using genome-wide RNA-binding data, Xue et al. (2009) draw a regulatory map in this issue of Molecular Cell for the much-studied polypyrimidine tract-binding protein (PTB) that reveals a unique paradigm in posttranscriptional gene regulation.
Corrionero
Anna
A
Centre de Regulació Genòmica, Barcelona, Spain.
Valcárcel
Juan
J
D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D006367:HeLa Cells; D006801:Humans; D038941:Polypyrimidine Tract-Binding Protein / Q000235:genetics / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional; D012326:RNA Splicing; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
D012333:RNA, Messenger; D038941:Polypyrimidine Tract-Binding Protein