title: Role of left ventricular twist mechanics in the assessment of cardiac dyssynchrony in heart failure.
abstract: The authors discuss an incremental value of assessing left ventricular (LV) twist mechanics in patients with heart failure (HF) and its potential usefulness in characterizing response to cardiac resynchronization therapy (CRT) and reversal of LV remodeling at 6 months follow-up. They also underscore a critical relationship between LV lead position and changes in LV twist after CRT, and suggest that the reversal of LV remodeling in HF patients following CRT primarily results from restoration of the global sequence of LV twist mechanics.
authors.affiliation: Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Matteo
authors.initials: M
authors.lastname: Bertini
authors.forename: Partho P
authors.initials: PP
authors.lastname: Sengupta
authors.forename: Gaetano
authors.initials: G
authors.lastname: Nucifora
authors.forename: Victoria
authors.initials: V
authors.lastname: Delgado
authors.forename: Arnold C T
authors.initials: AC
authors.lastname: Ng
authors.forename: Nina Ajmone
authors.initials: NA
authors.lastname: Marsan
authors.forename: Miriam
authors.initials: M
authors.lastname: Shanks
authors.forename: Rutger R J
authors.initials: RJ
authors.lastname: van Bommel
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
authors.forename: Jagat
authors.initials: J
authors.lastname: Narula
authors.forename: Jeroen J
authors.initials: JJ
authors.lastname: Bax
mesh_terms: D002304:Cardiac Pacing, Artificial; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D013997:Time Factors; D014102:Torsion Abnormality / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D054159:Torsion, Mechanical; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling