title: [Clinical study of tissue preservation of extraction socket with Bio-Oss collagen and acellular dermal matrix].
abstract: OBJECTIVE
  To evaluate the clinical and histological results of extraction socket preservation using Bio-Oss collagen and acellular dermal matrix (ADM).
  
  
  METHODS
  From November 2005 to June 2006, a total of 11 cases underwent extraction socket preservation with Bio-Oss collagen and ADM in 14 extraction sites. Ten cases with 10 teeth undergoing extraction without bone graft served as control group. Clinical and histological examinations were conducted. Pre-and postoperative alveolar ridge width and attached gingival width were measured and statistically analyzed.
  
  
  RESULTS
  All the grafted sockets healed uneventfully except one. Thirteen implants were placed 3 - 5 months after extraction. After 4 to 6 months permanent restorations were delivered. The mean follow-up time was 27.9 months (24 to 31 months). In the control group the sockets healed uneventfully, while hard and soft tissue collapsed obviously 3 months after extraction. No significant difference was found in the width of alveolar ridge and attached gingiva before and after extraction in the bone graft group (P > 0.05). The width of alveolar ridge before (7.69 + or - 0.48) mm and after extraction (7.68 + or - 0.48) mm and in the width of attached gingiva before (4.36 + or - 1.02) mm and after extraction (4.32 + or - 0.98) mm in the bone graft group (P > 0.05). Histological examination showed adequate new bone formation around Bio-Oss particles 3 months after operation. The specimen was free of inflammatory cells.
  
  
  CONCLUSIONS
  It's effective to preserve the extraction sockets with Bio-Oss collagen and ADM and the short-term results were predictable.
authors.affiliation: Center of Dental Implantation, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Xiu-lian
authors.initials: XL
authors.lastname: Hu
authors.forename: Ye
authors.initials: Y
authors.lastname: Lin
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Hui
authors.initials: H
authors.lastname: Wu
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Qiu
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D062088:Acellular Dermis; D000328:Adult; D003094:Collagen / Q000627:therapeutic use; D003758:Dental Implantation, Endosseous / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008903:Minerals / Q000627:therapeutic use*; D014081:Tooth Extraction / Q000379:methods; D020390:Tooth Socket / Q000601:surgery
chemical_list: C077540:Bio-Oss; D008903:Minerals; D003094:Collagen