title: Emerging Salmonella Paratyphi A enteric fever and changing trends in antimicrobial resistance pattern of salmonella in Shimla.
abstract: This retrospective study incorporates a six years, six months (January 2000-June 2006) laboratory data comprising 258 isolates of Salmonella. Cultures were identified by standard methods. Salmonella enterica serotype Typhi (S.Typhi) was the more frequent serotype isolated i.e., 61.62% with the remaining 38.37% being Salmonella enterica serotype Paratyphi A (S. Paratyphi A). There was emergence of S. Paratyphi A as the predominant serotype in 2003-2004 with resurgence of serotype Typhi thereon. A total of 66.27% isolates were resistant to one or more antibiotics. MDR S. Typhi was 10.69% and while 13.13% were MDR S. Paratyphi A. There was decrease in resistance to ampicillin, cotrimoxazole in 2004 and nalidixic acid beyond 2005 and increase in resistance to cefuroxime. We also documented a decrease in resistance to ciprofloxacin after 2005.
authors.affiliation: Department of Microbiology, IGMC, Shimla - 171 001, India.
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.forename: S
authors.initials: S
authors.lastname: Thakur
authors.forename: A
authors.initials: A
authors.lastname: Kanga
authors.forename: G
authors.initials: G
authors.lastname: Singh
authors.forename: P
authors.initials: P
authors.lastname: Gupta
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D006801:Humans; D007194:India / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D010284:Paratyphoid Fever / Q000453:epidemiology* / Q000382:microbiology; D012189:Retrospective Studies; D012482:Salmonella paratyphi A / Q000187:drug effects* / Q000302:isolation & purification*; D012485:Salmonella typhi / Q000187:drug effects* / Q000302:isolation & purification*; D014435:Typhoid Fever / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents