title: Proposal of a punch biopsy protocol as a pre-requisite for the establishment of a tissue bank from resected esophageal tumors.
abstract: With the development of tissue banking, a need for homogeneous methods of collection, processing, and storage of tissue has emerged. We describe the implementation of a biological bank in a high-volume, tertiary care University referral center for esophageal cancer surgery. We also propose an original punch biopsy technique of the surgical specimen. The method proved to be simple, reproducible, and not expensive. Unified standards for specimen collection are necessary to improve results of specimen-based diagnostic testing and research in surgical oncology.
authors.affiliation: Department of Medical and Surgical Sciences, Division of General Surgery, IRCCS Policlinico San Donato, University of Milano Medical School, Milan, Italy. luigi.bonavina@unimi.it
authors.forename: Luigi
authors.initials: L
authors.lastname: Bonavina
authors.forename: Letizia
authors.initials: L
authors.lastname: Laface
authors.forename: Stefano
authors.initials: S
authors.lastname: Picozzi
authors.forename: Marco
authors.initials: M
authors.lastname: Nencioni
authors.forename: Stefano
authors.initials: S
authors.lastname: Siboni
authors.forename: Davide
authors.initials: D
authors.lastname: Bona
authors.forename: Andrea
authors.initials: A
authors.lastname: Sironi
authors.forename: Francesca
authors.initials: F
authors.lastname: Sorba
authors.forename: Claudio
authors.initials: C
authors.lastname: Clemente
mesh_terms: D001706:Biopsy / Q000379:methods*; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008495:Medical Oncology; D010340:Pathology, Surgical; D013048:Specimen Handling / Q000379:methods* / Q000592:standards*; D014015:Tissue Banks / Q000592:standards