title: Prognostic factors in desmoid-type fibromatosis: a clinicopathological and immunohistochemical analysis of 46 cases.
abstract: OBJECTIVE
  To determine risk factors for recurrence of desmoid-type fibromatosis (aggressive fibromatosis).
  
  
  METHODS
  Forty-six cases of desmoid-type fibromatosis in Taiwanese patients were analysed for an association between tumour recurrence and clinical features, pathology, and the presence of p53 protein and beta-catenin on immunohistochemical staining.
  
  
  RESULTS
  Six (13%) of 46 patients developed recurrence after surgical resection. The only factor significantly associated with tumour recurrence was positive surgical margin (p = 0.035).
  
  
  CONCLUSIONS
  A positive surgical margin is a risk factor for recurrence of desmoid-type fibromatosis.
authors.affiliation: Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Pei-Wen
authors.initials: PW
authors.lastname: Huang
authors.forename: Chi-Yuan
authors.initials: CY
authors.lastname: Tzen
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D005260:Female; D018221:Fibromatosis, Abdominal / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D018222:Desmoid Tumors / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012307:Risk Factors; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D051176:beta Catenin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; C495270:CTNNB1 protein, human; D016159:Tumor Suppressor Protein p53; D051176:beta Catenin