title: Pelvic floor reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection.
abstract: OBJECTIVE
  Patients who undergo cylindrical abdominoperineal resection can have significant complications, especially those who require pelvic reconstruction using myocutaneous flaps. Reconstruction using a biomaterial may be a novel alternative. The purpose of this study is to report the initial results of pelvic reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection.
  
  
  METHODS
  Between January 2008 and February 2009, pelvic floor reconstruction was performed in 12 consecutive patients who underwent cylindrical abdominoperineal resection for advanced ultralow rectal cancer.
  
  
  RESULTS
  Two weeks after the operation, primary complete healing of the perineal wound was seen in 11 patients. At a median follow-up of 8 months, there was no perineal wound breakdown, bulge, or herniation. One patient had an asymptomatic seroma, one patient had a perineal wound infection, and 4 patients had perineal pain that resolved.
  
  
  CONCLUSIONS
  Human acellular dermal matrix provided a safe alternative for the reconstruction of large pelvic defect in the patients after cylindrical abdominoperineal resection.
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
authors.forename: Jia Gang
authors.initials: JG
authors.lastname: Han
authors.forename: Zhen Jun
authors.initials: ZJ
authors.lastname: Wang
authors.forename: Zhi Gang
authors.initials: ZG
authors.lastname: Gao
authors.forename: Hui Min
authors.initials: HM
authors.lastname: Xu
authors.forename: Zeng Hui
authors.initials: ZH
authors.lastname: Yang
authors.forename: Mu Lan
authors.initials: ML
authors.lastname: Jin
mesh_terms: D034861:Abdominal Wall / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D001705:Bioprosthesis; D020405:Dermis / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017773:Pelvic Floor / Q000601:surgery*; D010502:Perineum / Q000601:surgery; D011183:Postoperative Complications / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012004:Rectal Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D016038:Skin Transplantation / Q000379:methods*; D016896:Treatment Outcome