title: [Diaphragm frozen homograft for rats' abdominal wall defects repair].
abstract: OBJECTIVE
  To analyse the morphology and biomechanics of diaphragma frozen homografts used for rats' abdominal wall defects repair.
  
  
  METHODS
  Thirty wistar rats with abdominal wall resection and reconstruction using frozen diaphragma homografts were compared to twenty other rats submitted to abdominal wall incision and closure (control). Animals were euthanized after 3 and 6 months and abdominal walls were avaliated histologically with H/E and Picrosiriud Red staining and tensiometric evaluation.
  
  
  RESULTS
  The tensiometric parameters were greater in the experimental group at 3 months after surgery. The percentage of mature collagen was significantly greater at 6 months after surgery in control and experimental groups. Tensiometric parameters and type I collagen as well maturation collagen index and rupture maximal strength were statistically correlated after 3 and 6 months.
  
  
  CONCLUSIONS
  Frozen diaphragma homograft can be an alternative to repair the defects of abdominal wall.
authors.affiliation: Mestre em Clínica Cirúrgica pela Universidade Federal do Paraná, UFPR, BR. paolabrolin@yahoo.com.br
authors.forename: Paola Maria Brolin
authors.initials: PM
authors.lastname: Santis-Isolan
authors.forename: Miguel Angelo
authors.initials: MA
authors.lastname: Agulham
authors.forename: Gustavo Rassier
authors.initials: GR
authors.lastname: Isolan
authors.forename: Elizabeth Milla
authors.initials: EM
authors.lastname: Tambara
authors.forename: Sérgio Bernardo
authors.initials: SB
authors.lastname: Tenório
authors.forename: Ana Cristina Lira
authors.initials: AC
authors.lastname: Sobral
authors.forename: Antônio Ernesto da
authors.initials: AE
authors.lastname: Silveira
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D001696:Biomechanical Phenomena; D003964:Diaphragm / Q000637:transplantation*; D005615:Freezing; D051381:Rats; D017208:Rats, Wistar