Spatially mineralized self-assembled polymeric nanocarriers with enhanced robustness and controlled drug-releasing property.
Polymer micelles with bioabsorbable mineralized calcium phosphate nanoshells have been synthesized and demonstrated to be robust nanocarriers for efficient intracellular drug delivery.
Lee
Hong Jae
HJ
Department of Oral Biology & Institute of Oral Biology, School of Dentistry, Kyung Hee University, Seoul 130-701, Korea.
Kim
Sung Eun
SE
Kwon
Il Keun
IK
Park
Chiyoung
C
Kim
Chulhee
C
Yang
Jaemoon
J
Lee
Sang Cheon
SC
D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy; D002130:Calcium Phosphates / Q000138:chemical synthesis / Q000737:chemistry*; D045744:Cell Line, Tumor; D003692:Delayed-Action Preparations / Q000138:chemical synthesis / Q000737:chemistry*; D004317:Doxorubicin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008823:Micelles; D057145:Nanoshells / Q000737:chemistry* / Q000648:ultrastructure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry
D000903:Antibiotics, Antineoplastic; D002130:Calcium Phosphates; D003692:Delayed-Action Preparations; D008823:Micelles; D011108:Polymers; D004317:Doxorubicin; C020243:calcium phosphate