title: FANCM: A landing pad for the Fanconi Anemia and Bloom's Syndrome complexes.
abstract: In this issue of Molecular Cell, Deans and West (2009) reveal the molecular basis of the phenotypic similarities between Fanconi Anemia (FA) and Bloom's Syndrome, identifying FANCM as the anchor for both FA and Bloom's complexes at the site of the DNA interstrand crosslink.
authors.affiliation: Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Vinciguerra
authors.forename: Alan D
authors.initials: AD
authors.lastname: D'Andrea
mesh_terms: D001816:Bloom Syndrome / Q000235:genetics / Q000378:metabolism; D004249:DNA Damage; D004265:DNA Helicases / Q000235:genetics / Q000378:metabolism*; D004260:DNA Repair; D005199:Fanconi Anemia / Q000235:genetics / Q000378:metabolism; D006801:Humans; D010641:Phenotype; D053484:RecQ Helicases / Q000235:genetics / Q000378:metabolism
chemical_list: C097151:Bloom syndrome protein; C518295:FANCM protein, human; D004265:DNA Helicases; D053484:RecQ Helicases