title: Vinyl sulfone: a versatile function for simple bioconjugation and immobilization.
abstract: The easy functionalization of tags and solid supports with the vinyl sulfone function is a valuable tool in omic sciences that allows their coupling with the amine and thiol groups present in the proteogenic residues of proteins, in mild and green conditions compatible with their biological function.
authors.affiliation: Departamento de Q. Orgánica, Facultad de Ciencia, Instituto de Biotecnologia, Universidad de Granada, Granada, 18071 SPAIN.
authors.forename: Julia
authors.initials: J
authors.lastname: Morales-Sanfrutos
authors.forename: Javier
authors.initials: J
authors.lastname: Lopez-Jaramillo
authors.forename: Mariano
authors.initials: M
authors.lastname: Ortega-Muñoz
authors.forename: Alicia
authors.initials: A
authors.lastname: Megia-Fernandez
authors.forename: Francisco
authors.initials: F
authors.lastname: Perez-Balderas
authors.forename: Fernando
authors.initials: F
authors.lastname: Hernandez-Mateo
authors.forename: Francisco
authors.initials: F
authors.lastname: Santoyo-Gonzalez
mesh_terms: D000588:Amines / Q000737:chemistry; D000818:Animals; D002417:Cattle; D006863:Hydrogen-Ion Concentration; D055767:Immobilized Proteins / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D008958:Models, Molecular; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry; D012235:Rhodamines / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry; D013194:Staining and Labeling; D013450:Sulfones / Q000138:chemical synthesis / Q000737:chemistry*; D013696:Temperature
chemical_list: D000588:Amines; D055767:Immobilized Proteins; D007202:Indicators and Reagents; D011506:Proteins; D012235:Rhodamines; D013450:Sulfones; C009873:divinyl sulfone; D012822:Silicon Dioxide; C029773:rhodamine B