title: Relationship between mood disturbance and sleep quality in oncology outpatients at the initiation of radiation therapy.
abstract: OBJECTIVE
  The purpose of this study was to describe the occurrence of significant mood disturbance and evaluate for differences in sleep quality among four mood groups (i.e., neither anxiety nor depression, only anxiety, only depression, anxiety and depression) prior to the initiation of radiation therapy (RT).
  
  
  METHODS
  Patients (n=179) with breast, prostate, lung, and brain cancer were evaluated prior to the initiation of RT using the Pittsburgh Sleep Quality Index (PSQI), the Center for Epidemiological Studies Depression Scale, and the Spielberger State Anxiety Inventory. Differences in sleep disturbance among the four mood groups were evaluated using analyses of variance.
  
  
  RESULTS
  While 38% of the patients reported some type of mood disturbance, 57% of the patients reported sleep disturbance. Patients with clinically significant levels of anxiety and depression reported the highest levels of sleep disturbance.
  
  
  CONCLUSIONS
  Overall, oncology patients with mood disturbances reported more sleep disturbance than those without mood disturbance. Findings suggest that oncology patients need to be assessed for mood and sleep disturbances.
authors.affiliation: School of Nursing, University of California, San Francisco, CA, USA.
authors.forename: Christina
authors.initials: C
authors.lastname: Van Onselen
authors.forename: Laura B
authors.initials: LB
authors.lastname: Dunn
authors.forename: Kathryn
authors.initials: K
authors.lastname: Lee
authors.forename: Marylin
authors.initials: M
authors.lastname: Dodd
authors.forename: Theresa
authors.initials: T
authors.lastname: Koetters
authors.forename: Claudia
authors.initials: C
authors.lastname: West
authors.forename: Steven M
authors.initials: SM
authors.lastname: Paul
authors.forename: Bradley E
authors.initials: BE
authors.lastname: Aouizerat
authors.forename: William
authors.initials: W
authors.lastname: Wara
authors.forename: Patrick
authors.initials: P
authors.lastname: Swift
authors.forename: Christine
authors.initials: C
authors.lastname: Miaskowski
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D001294:Attitude to Health; D002140:California / Q000453:epidemiology; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D005260:Female; D006301:Health Services Needs and Demand; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000532:radiotherapy; D015404:Nursing Methodology Research; D009859:Oncology Nursing; D011569:Psychiatric Status Rating Scales; D012893:Sleep Wake Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D011795:Surveys and Questionnaires