title: Oxidant/antioxidant status in premenstrual syndrome.
abstract: OBJECTIVE
  To investigate oxidant/antioxidant status in premenstrual syndrome (PMS).
  
  
  METHODS
  Study group (n = 20) consisted of PMS and control group (n = 21) consisted of normal menstruating women. The serum oxidant status was assessed by the lipid hydroperoxide (LHP), malondialdehyde (MDA) and protein carbonyl (PC); the antioxidant status was assessed by the total thiol (T-SH) and total antioxidant capacity (TAC).
  
  
  RESULTS
  The study and control groups revealed no statistical difference, in terms of day 3 LHP, MDA, PC, T-SH and TAC levels. There were no significant differences between groups in terms of day 21 MDA, PC and T-SH levels. However, day 21 LHP levels were increased and TAC levels were decreased in the study group compared with the control group.
  
  
  CONCLUSIONS
  Increased oxidative stress and reduced antioxidant capacity may occur in PMS. It can be speculated that the imbalance of oxidant/antioxidant systems may be a cause or the consequence of the various stress symptoms in PMS.
authors.affiliation: Department of Obstetric and Gynecology, University of Fatih, Yukari Ayranci, Ankara, Turkey. candanduvan@yahoo.com
authors.forename: Candan Iltemir
authors.initials: CI
authors.lastname: Duvan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Cumaoglu
authors.forename: Nilgun Ozturk
authors.initials: NO
authors.lastname: Turhan
authors.forename: Cimen
authors.initials: C
authors.lastname: Karasu
authors.forename: Hasan
authors.initials: H
authors.lastname: Kafali
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood; D008315:Malondialdehyde / Q000097:blood; D016877:Oxidants / Q000097:blood*; D011293:Premenstrual Syndrome / Q000097:blood*; D050050:Protein Carbonylation; D013438:Sulfhydryl Compounds / Q000097:blood; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis; D055815:Young Adult
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; D016877:Oxidants; D013438:Sulfhydryl Compounds; D017392:Thiobarbituric Acid Reactive Substances; D008315:Malondialdehyde