Facile synthesis of robust and biocompatible gold nanoparticles.
Biocompatible and robust gold nanoparticles (AuNPs) were prepared via a simple synthetic strategy employing dextran as a reducing agent and surface coating material. Cross-linking and amination of the surface-coated dextran significantly improved the colloidal stability of AuNPs and rendered the nanoparticles more amenable to bioconjugation.
Jang
Hongje
H
Department of Chemistry, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea.
Kim
Young-Kwan
YK
Ryoo
Soo-Ryoon
SR
Kim
Mi-Hee
MH
Min
Dal-Hee
DH
D000586:Amination; D001672:Biocompatible Materials / Q000737:chemistry*; D002470:Cell Survival; D003911:Dextrans / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
D001672:Biocompatible Materials; D003911:Dextrans; D006046:Gold