Ceftriaxone-induced toxic epidermal necrolysis mimicking burn injury: a case report.
BACKGROUND
Toxic epidermal necrolysis is a rare exfoliative disorder with a high mortality rate.


METHODS
We present a 70-year-old woman of Iranian descent who presented with toxic epidermal necrolysis that was initially diagnosed as a scald burn. Further anamnesis prompted by spread of the lesions during hospitalization revealed that the patient had been receiving ceftriaxone for several days. To the best of our knowledge, this is the first case of ceftriaxone-induced toxic epidermal necrolysis in the English literature.


CONCLUSIONS
Toxic epidermal necrolysis is an acute, life-threatening, exfoliative disorder with a high mortality rate. High clinical suspicion, prompt recognition, and initiation of supportive care is mandatory. Thorough investigation of the pathogenetic mechanisms is fundamental. Optimal treatment guidelines are still unavailable.
Cohen
Sarit
S
Department of Plastic Surgery, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel.
Billig
Allan
A
Ad-El
Dean
D