title: EEG in adolescent anorexia nervosa: impact of refeeding and weight gain.
abstract: OBJECTIVE
  To examine resting awake EEG in adolescent AN participants before and after refeeding to determine if EEG abnormalities in Anorexia Nervosa (AN) are reversible.
  
  
  METHODS
  In 37 adolescent first admission AN patients and 45 healthy controls, EEG was recorded during short duration "eyes open" and "eyes closed" awake resting conditions. Repeat testing occurred in 28 AN participants after refeeding and subsequent weight gain.
  
  
  RESULTS
  In "eyes open," underweight AN participants exhibit reduced relative alpha power and increased beta power in frontal brain regions. A significant increase in alpha, and decrease in beta and delta power was observed within participants after refeeding. In "eyes closed", underweight AN participants had elevated theta in parietal-occipital regions which remained after refeeding.
  
  
  CONCLUSIONS
  EEG abnormalities (reduced alpha/increased beta power) in AN normalizes with refeeding, while increased theta power persists in parietal-occipital regions in an eyes closed context.
authors.affiliation: The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Westmead Hospital, Westmead, Sydney, New South Wales 2145, Australia. ainslieh@psych.usyd.edu.au
authors.forename: Ainslie
authors.initials: A
authors.lastname: Hatch
authors.forename: Sloane
authors.initials: S
authors.lastname: Madden
authors.forename: Michael R
authors.initials: MR
authors.lastname: Kohn
authors.forename: Simon
authors.initials: S
authors.lastname: Clarke
authors.forename: Stephen
authors.initials: S
authors.lastname: Touyz
authors.forename: Evian
authors.initials: E
authors.lastname: Gordon
authors.forename: Leanne M
authors.initials: LM
authors.lastname: Williams
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000178:diet therapy / Q000503:physiopathology*; D001145:Arrhythmias, Cardiac; D016022:Case-Control Studies; D002648:Child; D004435:Eating; D004569:Electroencephalography; D005260:Female; D006801:Humans; D015430:Weight Gain