title: Two new iridoid glucosides from Hedyotis diffusa.
abstract: Two new iridoid glucosides, named diffusosides A and B, were isolated from the aerial part of Hedyotis diffusa Willd. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis and HRESIMS. These two compounds showed no cytotoxic activity against SMMC-7721, SW480, SW620, Bel7402, and HepG2 cells.
authors.affiliation: Laboratory of Bioactive Natural Products Chemistry, College of Pharmaceutical Sciences Zhejiang University, Hangzhou 310058, PR China.
authors.forename: Yongyong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Chunlin
authors.initials: C
authors.lastname: Fan
authors.forename: Wencai
authors.initials: W
authors.lastname: Ye
authors.forename: Jiabo
authors.initials: J
authors.lastname: Luo
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D032064:Hedyotis / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D039823:Iridoids; C553380:diffusoside A; C553381:diffusoside B