NetPath: a public resource of curated signal transduction pathways.
We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.
Kandasamy
Kumaran
K
Institute of Bioinformatics, International Tech Park, Bangalore 560066, India. kumaran@ibioinformatics.org
Mohan
S Sujatha
SS
Raju
Rajesh
R
Keerthikumar
Shivakumar
S
Kumar
Ghantasala S Sameer
GS
Venugopal
Abhilash K
AK
Telikicherla
Deepthi
D
Navarro
J Daniel
JD
Mathivanan
Suresh
S
Pecquet
Christian
C
Gollapudi
Sashi Kanth
SK
Tattikota
Sudhir Gopal
SG
Mohan
Shyam
S
Padhukasahasram
Hariprasad
H
Subbannayya
Yashwanth
Y
Goel
Renu
R
Jacob
Harrys K C
HK
Zhong
Jun
J
Sekhar
Raja
R
Nanjappa
Vishalakshi
V
Balakrishnan
Lavanya
L
Subbaiah
Roopashree
R
Ramachandra
Y L
YL
Rahiman
B Abdul
BA
Prasad
T S Keshava
TS
Lin
Jian-Xin
JX
Houtman
Jon C D
JC
Desiderio
Stephen
S
Renauld
Jean-Christophe
JC
Constantinescu
Stefan N
SN
Ohara
Osamu
O
Hirano
Toshio
T
Kubo
Masato
M
Singh
Sujay
S
Khatri
Purvesh
P
Draghici
Sorin
S
Bader
Gary D
GD
Sander
Chris
C
Leonard
Warren J
WJ
Pandey
Akhilesh
A
D022126:Access to Information; D000818:Animals; D017209:Apoptosis; D001671:Biochemistry / Q000379:methods; D002465:Cell Movement; D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D007107:Immune System; D007376:Interleukin-2 / Q000378:metabolism; D008954:Models, Biological; D008957:Models, Genetic; D025941:Protein Interaction Mapping; D015398:Signal Transduction; D012984:Software; D014158:Transcription, Genetic
D007376:Interleukin-2