A note on langerhans cells in the oesophagus epithelium of domesticated mammals.
Using the zinc-iodide osmium tetroxide (ZIO) method, TEM and immunohistochemistry (for CD1a and langerin), the study demonstrates Langerhans cells in the oesophageal epithelium of domesticated mammals (herbivores: horse, cattle, goat; omnivores: pig, dog, laboratory rat; carnivores: cat), although with variations between the species. The ZIO method and TEM showed this cell type in the cat and, sporadically, in the horse; CD1a (+) Langerhans cells were demonstrated in the ovine, porcine and murine oesophagus. Positive staining for langerin was detected in single cells of the caprine, canine, murine and feline oesophagus and more distinct in almost all the cell layers of the equine and porcine oesophagus epithelium. The findings are discussed comparing specifically the results for CD1a and langerin, whereby the latter C-type lectin may be of importance in species with a rather thick oesophagus epithelium, such as that present in the plantivorous and most of the omnivorous animals, where antigenic pressure is reduced.
Meyer
W
W
Institute for Anatomy, University of Veterinary Medicine Hannover Foundation, 30173 Hannover, Germany. wilfried.meyer@tiho-hannover.de
Hornickel
I
I
Schoennagel
B
B
D000818:Animals; D000829:Animals, Domestic / Q000033:anatomy & histology*; D018949:Antigens, CD1 / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D002415:Cats; D002417:Cattle; D004396:Coloring Agents / Q000737:chemistry; D004285:Dogs; D004848:Epithelium / Q000648:ultrastructure; D004947:Esophagus / Q000648:ultrastructure*; D006041:Goats / Q000033:anatomy & histology; D006736:Horses / Q000033:anatomy & histology; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000648:ultrastructure*; D037181:Lectins, C-Type / Q000032:analysis; D037241:Mannose-Binding Lectins / Q000032:analysis; D051379:Mice; D046529:Microscopy, Electron, Transmission; D009993:Osmium Tetroxide / Q000737:chemistry; D051381:Rats; D017967:Zinc Compounds / Q000737:chemistry
D018949:Antigens, CD1; D000954:Antigens, Surface; C419393:CD1a antigen; C498497:Cd207 protein, mouse; D004396:Coloring Agents; D037181:Lectins, C-Type; D037241:Mannose-Binding Lectins; D017967:Zinc Compounds; C035252:osmium zinc iodide; D009993:Osmium Tetroxide