[Study on epidemiological effect of the freeze-dried attenuated live varicella vaccine].
OBJECTIVE
To evaluate the safety and epidemiological effect of the Freeze-dried Live attenuated varicella vaccine.


METHODS
A random, double-blind control clinical trial was adopted.


RESULTS
In the observation period, the incidence of varicella was 0.8 per thousand in the experimental group and 8.7 per thousand in control group. There was a significant difference (B.P=0.000017). Vaccine effectiveness (VE(%)) was 90.8%, the lower limit of 95%CI was 88.7%.


CONCLUSIONS
The varicella vaccine produced by Changchun keygen biological products co., Ltd. was safe and effective.
Ma
Fu-bao
FB
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu, China.
Luo
Lin-yun
LY
Zhang
Long-hua
LH
D002644:Chickenpox / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*; D019433:Chickenpox Vaccine / Q000008:administration & dosage* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004353:Drug Evaluation, Preclinical; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology
D019433:Chickenpox Vaccine; D014613:Vaccines, Attenuated