title: [Effect of measles control at different stages in Binzhou Municipal].
abstract: OBJECTIVE
  To evaluate the effect of measles control at different stages in Binzhou of Shandong.
  
  
  METHODS
  The data of measles incidence, measles vaccine (MV) coverage, the population immune levels of measles IgG antibody from 1956 to 2008, and the cost-benefit of measles control were analyzed.
  
  
  RESULTS
  The measles incidences were declined continually with implementing the strategies of measles control. Measles vaccine coverages have been keeping at the level of 87.12%-93.45% and the population immune levels of measles IgG antibody have been remaining at high level after implemention EPI. According to the progress of MV immunization strategy, the process of measles control could be divided into stage A (1956-1966, no specific immunization conducted), stage B (1967-1978, MV began to popularized), stage C (1979-1997, the EPI was implemented) and stage D (1998-2008, accelerated measles control and elimination). To compared between stage B and stage A, stage C and stage B, stage D and stage C, the average annual cases were decreased 9989, 18 500, and 378 respectirely, and the average annual dead cases were reduced 267, 49 and 50 respectively. The cost-benefit ratio was 1:22.97 for total 41 years on the process of the measles control and elimination from 1967 to 2008.
  
  
  CONCLUSIONS
  The effect was obtained on the process of measles control in Binzhou city. More efforts should be made to reach the target of measles elimination.
authors.affiliation: Binzhou Municipal Center for Disease Control and Prevention, Bizhou 256618, Shandong, China.
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Cao
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.forename: Zhi-Guang
authors.initials: ZG
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003140:Communicable Disease Control / Q000191:economics / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D008458:Measles Vaccine / Q000008:administration & dosage; D011159:Population Surveillance; D014505:Urban Population; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine