Inhomogeneous bone marrow uptake caused by G-CSF mimics multiple bone metastases on FDG-PET.
Administration of granulocyte colony stimulating factor can cause homogeneous hypermetabolic activity of bone marrow in positron emission tomography using F-18-fluorodeoxyglucose. We report a case in which positron emission tomography demonstrated multiple foci of hypermetabolic activity in the bone marrow, which was considered an early effect of granulocyte colony stimulating factor, and not multiple osseous metastases.
Nakamoto
Yuji
Y
Department of Diagnostic Radiology, Kyoto University Hospital, Sakyo-ku, Kyoto, Japan. ynakamo1@kuhp.kyoto-u.ac.jp
Suga
Tsuyoshi
T
Hara
Tadashi
T
Ishizu
Koichi
K
Togashi
Kaori
K
D016477:Artifacts; D001853:Bone Marrow / Q000187:drug effects / Q000378:metabolism*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000556:secondary*; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography
D019788:Fluorodeoxyglucose F18; D016179:Granulocyte Colony-Stimulating Factor