title: A new map to understand deubiquitination.
abstract: Deubiquitination is a crucial mechanism in ubiquitin-mediated signalling networks. The importance of Dubs (deubiquitinating enzymes) as regulators of diverse cellular processes is becoming ever clearer as new roles are elucidated and new pathways are shown to be affected by this mechanism. Recent work, reviewed in the present paper, provides new perspective on the widening influence of Dubs and a new tool to focus studies of not only Dub interactions, but also potentially many more cellular systems.
authors.affiliation: Institut de Biologia Molecular de Barcelona, CSIC, Barcelona Scientific Park, Baldiri i Reixac 15-21, 08028 Barcelona, Spain.
authors.forename: Elijah J
authors.initials: EJ
authors.lastname: Katz
authors.forename: Marta
authors.initials: M
authors.lastname: Isasa
authors.forename: Bernat
authors.initials: B
authors.lastname: Crosas
mesh_terms: D010450:Endopeptidases / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D015203:Reproducibility of Results; D015398:Signal Transduction / Q000502:physiology*; D025801:Ubiquitin / Q000378:metabolism*; D043222:Ubiquitin Thiolesterase / Q000235:genetics / Q000378:metabolism
chemical_list: D025801:Ubiquitin; D010450:Endopeptidases; D043222:Ubiquitin Thiolesterase