Arrhythmogenic right ventricular dysplasia: from genetics to treatment.
Arrhythmogenic right ventricular dysplasia (ARVD), also known as arrhythmogenic right ventricular cardiomyopathy, is a genetic cause for sudden cardiac arrest. In ARVD, there is progressive replacement of normal myocytes, with fat and fibrous tissue, predominantly in the right ventricle that predisposes the individual to arrhythmias. Patients who are identified with this condition are risk stratified; those at high risk are recommended to have implanted cardioverter defibrillators.
Khan
Aslam
A
Division of Cardiology, St Luke's-Roosevelt Hospital Center, Columbia University College of Physicians & Surgeons, New York, NY 10019, USA.
Mittal
Suneet
S
Sherrid
Mark V
MV
D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000150:complications* / Q000235:genetics* / Q000628:therapy; D016757:Death, Sudden, Cardiac / Q000209:etiology* / Q000517:prevention & control; D017147:Defibrillators, Implantable; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D009206:Myocardium / Q000473:pathology; D011379:Prognosis; D018570:Risk Assessment