Lung metastasis 21 years after initial diagnosis of osteosarcoma: a case report.
BACKGROUND
To the best of our knowledge, this case report describes the longest disease-free interval between primary diagnosis and metastatic recurrence of an osteosarcoma.


METHODS
A 35-year-old Caucasian American man presented with asymptomatic lung metastases 21 years after being diagnosed and treated for lower extremity osteosarcoma. He underwent curative lung resection, but 2 years thereafter developed metastatic disease in the scapula and tibia and, after resection and chemotherapy, is in remission 1 year later.


CONCLUSIONS
This case highlights the importance of long follow-up periods and continued surveillance of osteosarcoma patients after initial curative treatment.
Halldorsson
Ari
A
Division of Cardiothoracic Surgery, Department of Surgery, Texas Tech University, Lubbock, TX, USA.
Brooks
Steven
S
Montgomery
Sam
S
Graham
Suzanne
S