title: [Study on epidemiological effect of the freeze-dried attenuated live varicella vaccine].
abstract: OBJECTIVE
  To evaluate the safety and epidemiological effect of the Freeze-dried Live attenuated varicella vaccine.
  
  
  METHODS
  A random, double-blind control clinical trial was adopted.
  
  
  RESULTS
  In the observation period, the incidence of varicella was 0.8 per thousand in the experimental group and 8.7 per thousand in control group. There was a significant difference (B.P=0.000017). Vaccine effectiveness (VE(%)) was 90.8%, the lower limit of 95%CI was 88.7%.
  
  
  CONCLUSIONS
  The varicella vaccine produced by Changchun keygen biological products co., Ltd. was safe and effective.
authors.affiliation: Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu, China.
authors.forename: Fu-bao
authors.initials: FB
authors.lastname: Ma
authors.forename: Lin-yun
authors.initials: LY
authors.lastname: Luo
authors.forename: Long-hua
authors.initials: LH
authors.lastname: Zhang
mesh_terms: D002644:Chickenpox / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*; D019433:Chickenpox Vaccine / Q000008:administration & dosage* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004353:Drug Evaluation, Preclinical; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D019433:Chickenpox Vaccine; D014613:Vaccines, Attenuated