title: Epibulbar schwannoma in a 17-year-old boy and review of the literature.
abstract: A healthy, 17-year-old boy presented with a 2-month history of an epibulbar mass on the left eye. Slit lamp examination showed an amelanotic, translucent, round, well-circumscribed, superonasal subconjunctival nodule. On ultrasound biomicroscopy, the tumor was acoustically hollow. The lesion was excised intact, and cryotherapy was applied to the surrounding conjunctiva. Histopathologic examination revealed a tumor composed of spindle cells with slender cytoplasmic processes and bland cigar-shaped nuclei, consistent with schwannoma. Immunohistochemistry showed positivity for S100 protein. The patient had no signs of neurofibromatosis. There was no tumor recurrence after 18 months. This case shows that conjunctival schwannoma can present as a translucent, well-circumscribed subconjunctival mass.
authors.affiliation: Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Hakan
authors.initials: H
authors.lastname: Demirci
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Ralph C
authors.initials: RC
authors.lastname: Eagle
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D003230:Conjunctival Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D017679:Cryotherapy; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009915:Orbit
chemical_list: D014408:Biomarkers, Tumor