Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.
The use of iPSCs and tetraploid complementation for human reproductive cloning would raise profound ethical objections. Professional standards and laws that ban human reproductive cloning by somatic cell nuclear transfer should be revised to also forbid it by other methods, such as iPSCs via tetraploid complementation.
Lo
Bernard
B
Program in Medical Ethics, Department of Medicine, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA. bernie@medicine.ucsf.edu
Parham
Lindsay
L
Alvarez-Buylla
Arturo
A
Cedars
Marcelle
M
Conklin
Bruce
B
Fisher
Susan
S
Gates
Elena
E
Giudice
Linda
L
Halme
Dina Gould
DG
Hershon
William
W
Kriegstein
Arnold
A
Kwok
Pui-Yan
PY
Wagner
Richard
R
D000818:Animals; D001675:Bioethics; D002454:Cell Differentiation; D019976:Cloning, Organism / Q000941:ethics* / Q000379:methods; D017408:Guidelines as Topic; D006801:Humans; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology*