Unsaturated lactams: new inputs for povarov-type multicomponent reactions.
Unsaturated lactams with endo- or exocyclic C-C double bonds constitute a set of reactive inputs that serve as the electron-rich olefin component in Povarov reactions. These substrates afford the multicomponent adducts in convenient yields and offer a wide range of structural diversity. Postcondensation transformations allow direct access to a variety of lactam-fused and amide-substituted quinoline derivatives.
Vicente-García
Esther
E
Barcelona Science Park, Baldiri Reixac 10-12, 08028 Barcelona, Spain.
Catti
Federica
F
Ramón
Rosario
R
Lavilla
Rodolfo
R
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007769:Lactams / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
D000475:Alkenes; D007769:Lactams; D011804:Quinolines