Cardiac troponin I is released following high-intensity short-duration exercise in healthy humans.
It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known. We examined cardiac troponin I (cTnI) release pre-, during and post-30 min of high-intensity running exercise in eight recreationally active males (age 29±3 years; VO2peak 53±11 ml kg min(-1)). Following exercise, cTnI increased in six of the eight participants. Four participants showed a minimal response (<0.05 µg/l) post-exercise. In contrast, two participants showed a progressive increase in cTnI (>0.1 µg/l) following exercise which peaked 3-4 h post-exercise. cTnI returned below the detection limit of the assay in all bar one of the participants 24 h post-exercise. These data are the first to show that cTnI can be released following short-duration high-intensity exercise. Clinicians should be aware that exercise-induced release of cTnI is not limited to prolonged endurance activity.
Shave
Rob
R
Brunel University, Uxbridge, Middlesex, UK. Electronic address: rob.shave@brunel.ac.uk.
Ross
Peter
P
Brunel University, Uxbridge, Middlesex, UK.
Low
David
D
Brunel University, Uxbridge, Middlesex, UK.
George
Keith
K
Liverpool John Moores University, Liverpool, UK.
Gaze
David
D
Brunel University, Uxbridge, Middlesex, UK; St. Georges Hospital Medical School NHS Trust, Tooting, London, UK.
D000328:Adult; D015415:Biomarkers / Q000097:blood; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D012420:Running / Q000502:physiology*; D013997:Time Factors; D019210:Troponin I / Q000097:blood / Q000378:metabolism*
D015415:Biomarkers; D019210:Troponin I