[Pure red cell anaemia secondary to medullary B cell chronic lymphoproliferative disorders. A rare case].
Acquired erythroblastopenia is rather rare, more frequent in adult or old male. In absence of anti EPO antibody, it's associate to inhibition of the erythroid growth mediated by suppressive T lymphocytes, generally T8 or NK or mediated by IgG antibody in association with timoma, lymphoproliferative or immunological disorders, and other diseases. The course usually is chronic and follows that of the associate pathology. We report a case with pure red cell anaemia associated to non classified medullary B cell lymphoproliferative disorder in an old woman with complete remission after steroid therapy.
Rosada
Javier
J
Unità Operativa Medicina Interna IV, Azienda Ospedaliero-Universitaria, Pisa. javier_rosada@yahoo.it
Pérez
Yoel Anta
YA
Bindi
Massimo
M
Moruzzo
Daniela
D
Jacomino
Marcos A
MA
Días
Jacqueline
J
Castiglioni
Maido
M
D000328:Adult; D000367:Age Factors; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012010:Red-Cell Aplasia, Pure / Q000175:diagnosis / Q000209:etiology*; D012074:Remission Induction; D012737:Sex Factors; D013997:Time Factors
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011241:Prednisone