title: Contribution of hypoxia-measuring molecular imaging techniques to radiotherapy planning and treatment.
abstract: Hypoxia is related to poor prognosis because it is associated to chemo- and radioresistance. During recent years the evolution of imaging methods like PET/CT and MRI has meant the appearance of new perspectives with direct implications in radiation therapy. We discuss previous experiences in staging, planning and in the follow-up process with these techniques for measuring tumour hypoxia.
authors.affiliation: Servicio de Oncología Radioterápica, Consorcio Hospitalario Provincial de Castellón, Castellón, Spain. ferreralbiach@gmail.com
authors.forename: Carlos
authors.initials: C
authors.lastname: Ferrer Albiach
authors.forename: Antonio
authors.initials: A
authors.lastname: Conde Moreno
authors.forename: Marta
authors.initials: M
authors.lastname: Rodríguez Cordón
authors.forename: Virginia
authors.initials: V
authors.lastname: Morillo Macías
authors.forename: Ana
authors.initials: A
authors.lastname: Bouché Babiloni
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Beato Tortajada
authors.forename: Angel
authors.initials: A
authors.lastname: Sánchez Iglesias
authors.forename: Alicia
authors.initials: A
authors.lastname: Francés Muñoz
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D019788:Fluorodeoxyglucose F18; D006801:Humans; D000860:Hypoxia / Q000235:genetics / Q000378:metabolism*; D007150:Immunohistochemistry; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000532:radiotherapy* / Q000628:therapy*; D049268:Positron-Emission Tomography / Q000379:methods; D011379:Prognosis; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D014408:Biomarkers, Tumor; D019788:Fluorodeoxyglucose F18