A supramodal network for response inhibition.
Response inhibition is the capacity to suppress inappropriate actions and is considered to be a fundamental executive function. This study investigated whether the neural correlates of response inhibition are organized along supramodal or modality-specific principles. For this purpose, we used event-related functional magnetic resonance imaging in a go-nogo task with auditory and visual stimuli. Common activation relating to response inhibition across modalities was observed in a frontoparietal network including the ventrolateral prefrontal cortex. In contrast, there was no modality-specific activation related to response inhibition in the prefrontal cortex. These findings suggest that the neural correlates of response inhibition have a supramodal organization, which is consistent with its role as a core executive function.
Walther
Stephan
S
Section of Experimental Psychopathology, Department of Psychiatry, University of Heidelberg, Germany. stephan_walther@med.uni-heidelberg.de
Goya-Maldonado
Roberto
R
Stippich
Christoph
C
Weisbrod
Matthias
M
Kaiser
Stefan
S
D000328:Adult; D001931:Brain Mapping; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007266:Inhibition, Psychological; D008279:Magnetic Resonance Imaging; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D017397:Prefrontal Cortex / Q000502:physiology*; D055815:Young Adult