title: Should all embryos from day 1 rescue intracytoplasmic sperm injection be transferred during frozen-thawed cycles?
abstract: A retrospective analysis of a 5-year rescue intracytoplasmic sperm injection (ICSI) experience performed in 17 cases of complete IVF fertilization failure showed that the ongoing pregnancy rate per embryo transfer (ET) is much higher in a subsequent frozen-thawed cycles (40%, 2/5) than following a fresh ET (6.7%, 1/15). These results suggest that cryopreservation of all embryos, subsequently used in frozen-thawed cycles, might improve rescue ICSI outcome throughout a better synchronization of the embryo development with the endometrium.
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique-Biologie de la Reproduction-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique-Hôpitaux de Paris, Bondy, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Sermondade
authors.forename: Jean-Noël
authors.initials: JN
authors.lastname: Hugues
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cedrin-Durnerin
authors.forename: Christophe
authors.initials: C
authors.lastname: Poncelet
authors.forename: Brigitte
authors.initials: B
authors.lastname: Benzacken
authors.forename: Rachel
authors.initials: R
authors.lastname: Lévy
authors.forename: Christophe
authors.initials: C
authors.lastname: Sifer
mesh_terms: D000328:Adult; D015925:Cryopreservation; D004624:Embryo Transfer / Q000379:methods*; D004622:Embryo, Mammalian; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D005615:Freezing; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors; D017211:Treatment Failure