[Diaphragm frozen homograft for rats' abdominal wall defects repair].
OBJECTIVE
To analyse the morphology and biomechanics of diaphragma frozen homografts used for rats' abdominal wall defects repair.


METHODS
Thirty wistar rats with abdominal wall resection and reconstruction using frozen diaphragma homografts were compared to twenty other rats submitted to abdominal wall incision and closure (control). Animals were euthanized after 3 and 6 months and abdominal walls were avaliated histologically with H/E and Picrosiriud Red staining and tensiometric evaluation.


RESULTS
The tensiometric parameters were greater in the experimental group at 3 months after surgery. The percentage of mature collagen was significantly greater at 6 months after surgery in control and experimental groups. Tensiometric parameters and type I collagen as well maturation collagen index and rupture maximal strength were statistically correlated after 3 and 6 months.


CONCLUSIONS
Frozen diaphragma homograft can be an alternative to repair the defects of abdominal wall.
Santis-Isolan
Paola Maria Brolin
PM
Mestre em Clínica Cirúrgica pela Universidade Federal do Paraná, UFPR, BR. paolabrolin@yahoo.com.br
Agulham
Miguel Angelo
MA
Isolan
Gustavo Rassier
GR
Tambara
Elizabeth Milla
EM
Tenório
Sérgio Bernardo
SB
Sobral
Ana Cristina Lira
AC
Silveira
Antônio Ernesto da
AE
D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D001696:Biomechanical Phenomena; D003964:Diaphragm / Q000637:transplantation*; D005615:Freezing; D051381:Rats; D017208:Rats, Wistar