title: Calibration coefficient of reference brachytherapy ionization chamber using analytical and Monte Carlo methods.
abstract: A cylindrical graphite ionization chamber of sensitive volume 1002.4 cm(3) was designed and fabricated at Bhabha Atomic Research Centre (BARC) for use as a reference dosimeter to measure the strength of high dose rate (HDR) (192)Ir brachytherapy sources. The air kerma calibration coefficient (N(K)) of this ionization chamber was estimated analytically using Burlin general cavity theory and by the Monte Carlo method. In the analytical method, calibration coefficients were calculated for each spectral line of an HDR (192)Ir source and the weighted mean was taken as N(K). In the Monte Carlo method, the geometry of the measurement setup and physics related input data of the HDR (192)Ir source and the surrounding material were simulated using the Monte Carlo N-particle code. The total photon energy fluence was used to arrive at the reference air kerma rate (RAKR) using mass energy absorption coefficients. The energy deposition rates were used to simulate the value of charge rate in the ionization chamber and N(K) was determined. The Monte Carlo calculated N(K) agreed within 1.77 % of that obtained using the analytical method. The experimentally determined RAKR of HDR (192)Ir sources, using this reference ionization chamber by applying the analytically estimated N(K), was found to be in agreement with the vendor quoted RAKR within 1.43%.
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai 400094, India.
authors.forename: Sudhir
authors.initials: S
authors.lastname: Kumar
authors.forename: P
authors.initials: P
authors.lastname: Srinivasan
authors.forename: S D
authors.initials: SD
authors.lastname: Sharma
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D002138:Calibration; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007496:Iridium Radioisotopes; D009010:Monte Carlo Method; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*
chemical_list: D007496:Iridium Radioisotopes