Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N-acetylcysteine.
Electrochemical oxidation of acetaminophen has been studied in the presence of glutathione and acetylcysteine. Our results indicate that N-acetyl-p-benzoquinone-imine (NAPQI) participates in a catalytic reaction with glutathione and N-acetylcysteine. Also, the observed homogeneous rate constants of the reaction of NAPQI with glutathione and acetylcysteine were estimated.
Shayani-Jam
Hasan
H
Faculty of Chemistry, f Bu-Ali-Sina University, Hamedan, 65178-38683, Iran.
Nematollahi
Davood
D
D000082:Acetaminophen / Q000737:chemistry*; D000111:Acetylcysteine / Q000737:chemistry*; D018712:Analgesics, Non-Narcotic / Q000737:chemistry*; D004563:Electrochemistry; D005978:Glutathione / Q000737:chemistry*; D010084:Oxidation-Reduction
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D005978:Glutathione; D000111:Acetylcysteine