title: Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media.
abstract: An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.
authors.affiliation: Departamento de Química Orgánica (C-I), Universidad Autónoma de Madrid, 28049-Madrid, Spain. jose.aleman@uam.es
authors.forename: José
authors.initials: J
authors.lastname: Alemán
authors.forename: Virginia
authors.initials: V
authors.lastname: del Solar
authors.forename: Carmen
authors.initials: C
authors.lastname: Navarro-Ranninger
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007783:Lactones / Q000737:chemistry*; D015394:Molecular Structure; D010984:Platinum; D017671:Platinum Compounds / Q000737:chemistry*; D012997:Solvents; D014867:Water / Q000737:chemistry
chemical_list: D000480:Alkynes; D000970:Antineoplastic Agents; D007783:Lactones; D017671:Platinum Compounds; D012997:Solvents; D014867:Water; D010984:Platinum