title: Temperature course after transcranial surgery for Apert syndrome: a possible indicator for postoperative complication.
abstract: BACKGROUND
  Pyrexia after surgical procedure is a commonly observed phenomenon. However, it is not easy to distinguish pyrexia related to a postoperative complication from the normal temperature increase after surgery. The aims of this study were to establish a normal template for postoperative temperature course after transcranial surgery in patients with Apert syndrome and to investigate the correlation between the pattern of temperature increase and etiological factors.
  
  
  METHODS
  Seventy-seven sequential case notes of patients with Apert syndrome were retrospectively reviewed to collect postoperative temperature courses. The mean change of temperature was plotted on a graph with trend line to compare the feature of the course in each possible factor. A separate group of those who underwent fronto-orbital advancement was independently evaluated.
  
  
  RESULTS
  The temperature course had a bimodal distribution during the first 48 hours. However, those who underwent longer surgery, fronto-facial advancement, or those accompanied by complication seemed to have the more obvious third temperature peak around 50 hours postoperatively. This finding was also true in the independent fronto-orbital advancement group. Temperature courses without postoperative complication seemed to have bimodal distribution of temperature course; on the other hand, those with postoperative complication seemed to have the obvious third temperature peak around postoperative 50 hours.
  
  
  CONCLUSIONS
  Together with our previous study, it was concluded that pyrexia after transcranial surgery had a bimodal distribution as a normal course within the first 48 hours postoperatively. Moreover, it was suggested that the third temperature peak around 50 hours postoperatively could be an indicator for a postoperative complication.
authors.affiliation: Australian Craniofacial Unit, Women's and Children's Hospital, North Adelaide, Australia.
authors.forename: Ikkei
authors.initials: I
authors.lastname: Tamada
authors.forename: David J
authors.initials: DJ
authors.lastname: David
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Anderson
mesh_terms: D000168:Acrocephalosyndactylia / Q000601:surgery*; D001831:Body Temperature; D002675:Child, Preschool; D003399:Craniotomy / Q000379:methods; D005260:Female; D005334:Fever / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D012016:Reference Values; D012189:Retrospective Studies; D012307:Risk Factors