Regeneration in crinoids.
Regeneration is a biological phenomenon that occurs in a wide range of animals, and is considered to involve different types of cells including those that are considered to be stem cells. Among the echinoderms, which is a phylum with many regenerating members, crinoids (feather stars and sea lilies) are known to possess high potential of regeneration and are able to regenerate most of their organs. In particular, arm regeneration has been studied using the feather star. During regeneration, coelomocytes and amoebocytes originating from the coelomic canal and the brachial nerve, respectively, migrate to the distal wound area and are involved in the regenerative process. A blastema is formed at the regenerating tip and is derived from migratory amoebocytes. On the other hand, migratory coelomocytes contribute to regenerate the coelomic system. Cells proliferate at the blastema, coelomic canals and brachial nerve. Since the migrating cells differentiate into new structures of the arm, they are considered presumably undifferentiated multipotent stem cells. To deepen our understanding of stem cells in general, we may benefit from an approach from a comparative point of view. Further molecular analyses would increase our knowledge of stem cells in crinoids and allow comparative studies to be possible.
Kondo
Mariko
M
Misaki Marine Biological Station, Graduate School of Science and Center for Marine Biology, The University of Tokyo, 1024 Koajiro, Misaki, Miura, Kanagawa 238-0225, Japan. konmari@mmbs.s.u-tokyo.ac.jp
Akasaka
Koji
K
D000818:Animals; D005075:Biological Evolution; D002454:Cell Differentiation; D019070:Cell Lineage; D049109:Cell Proliferation; D004447:Echinodermata / Q000145:classification / Q000166:cytology* / Q000502:physiology*; D008954:Models, Biological; D009420:Nervous System / Q000166:cytology; D012038:Regeneration; D013234:Stem Cells / Q000166:cytology