title: School air quality related to dry cough, rhinitis and nasal patency in children.
abstract: Controls for indoor air quality (IAQ) in schools are not usually performed throughout Europe. The aim of this study was to assess the effects of IAQ on respiratory health of schoolchildren living in Norway, Sweden, Denmark, France and Italy. In the cross-sectional European Union-funded HESE (Health Effects of School Environment) Study, particulate matter with a 50% cut-off aerodynamic diameter of 10 microm (PM(10)) and CO(2) levels in a day of normal activity (full classroom) were related to wheezing, dry cough at night and rhinitis in 654 children (10 yrs) and to acoustic rhinometry in 193 children. Schoolchildren exposed to PM(10) >50 microg x m( -3) and CO(2) >1,000 ppm (standards for good IAQ) were 78% and 66%, respectively. All disorders were more prevalent in children from poorly ventilated classrooms. Schoolchildren exposed to CO(2) levels >1,000 ppm showed a significantly higher risk for dry cough (OR 2.99, 95% CI 1.65-5.44) and rhinitis (OR 2.07, 95% CI 1.14-3.73). By two-level (child, classroom) hierarchical analyses, CO(2) was significantly associated with dry cough (OR 1.06, 95% CI 1.00-1.13 per 100 ppm increment) and rhinitis (OR 1.06, 95% CI 1.00-1.11). Nasal patency was significantly lower in schoolchildren exposed to PM( 10) >50 microg x m(-3) than in those exposed to lower levels. A poor IAQ is frequent in European classrooms; it is related to respiratory disturbances and affects nasal patency.
authors.affiliation: Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy. marzia_simoni@libero.it
authors.forename: M
authors.initials: M
authors.lastname: Simoni
authors.forename: I
authors.initials: I
authors.lastname: Annesi-Maesano
authors.forename: T
authors.initials: T
authors.lastname: Sigsgaard
authors.forename: D
authors.initials: D
authors.lastname: Norback
authors.forename: G
authors.initials: G
authors.lastname: Wieslander
authors.forename: W
authors.initials: W
authors.lastname: Nystad
authors.forename: M
authors.initials: M
authors.lastname: Canciani
authors.forename: P
authors.initials: P
authors.lastname: Sestini
authors.forename: G
authors.initials: G
authors.lastname: Viegi
mesh_terms: D016902:Air Pollution, Indoor / Q000706:statistics & numerical data*; D002648:Child; D003371:Cough / Q000175:diagnosis / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D004781:Environmental Exposure / Q000706:statistics & numerical data; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012220:Rhinitis / Q000175:diagnosis / Q000453:epidemiology*; D023842:Rhinometry, Acoustic; D012574:Schools / Q000706:statistics & numerical data*; D013334:Students / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014691:Ventilation / Q000706:statistics & numerical data