Dramatically elevated circulating tumor cell numbers in a patient with small cell neuroendocrine carcinoma of the prostate.
Detection of circulating tumor cells in whole blood is a useful prognostic tool for patients with castration-resistant prostate cancer, as well as for patients with metastatic breast cancer and colorectal carcinoma. In this report, we present the case of a patient with neuroendocrine small cell prostate cancer with normal prostate-specific antigen levels throughout the course of disease but who had markedly elevated circulating tumor cells, as detected with the CellSearch (Veridex) system.
Chan
Fanny
F
Department of Medical Oncology, Nevada Cancer Institute, Las Vegas, NV 89135, USA.
Goodman
Oscar
O
Fink
Louis
L
Vogelzang
Nicholas J
NJ
Pomerantz
David
D
Khoury
Joseph D
JD
D014408:Biomarkers, Tumor / Q000097:blood; D018278:Carcinoma, Neuroendocrine / Q000097:blood* / Q000473:pathology*; D018288:Carcinoma, Small Cell / Q000097:blood* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology*
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen