title: [Mechanisms of Chlamydia trachomatis and herpes simplex virus persistence during viral-bacterial infection].
abstract: Possible mechanisms of persistence on the example of Chlamydia trachomatis in conditions of herpes simplex virus type 2 (HSV-2) superinfection in vitro and in vivo are described. Emergence of persisting forms of Chlamydia as well as factors influencing on this process are considered. Contemporary views on pathogenesis of viral-bacterial infection with HSV-2 and C. trachomatis as well as interactions of the agents with local immunity factors are described. It was suggested that there are signaling pathways through which HSV-2 changes life cycle of Chlamydia.
authors.forename: V A
authors.initials: VA
authors.lastname: Bekhalo
authors.forename: E V
authors.initials: EV
authors.lastname: Sysoliatina
authors.forename: E V
authors.initials: EV
authors.lastname: Nagurskaia
mesh_terms: D000818:Animals; D002690:Chlamydia Infections / Q000150:complications / Q000276:immunology* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000472:pathogenicity / Q000502:physiology*; D005260:Female; D006558:Herpes Genitalis / Q000150:complications / Q000276:immunology / Q000821:virology; D006561:Herpes Simplex / Q000150:complications / Q000276:immunology* / Q000821:virology; D018258:Herpesvirus 2, Human / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D007113:Immunity, Innate; D018928:Immunity, Mucosal; D008297:Male; D015163:Superinfection / Q000276:immunology / Q000382:microbiology / Q000821:virology; D014774:Virulence