title: Giant cell tumor of the frontal bone in an 18-month-old girl: a case report.
abstract: BACKGROUND
  Giant cell tumors (GCT) are benign, but locally aggressive primary bone neoplasms, that frequently occur in the epiphyses of the long bones. Less than 1% of all GCTs primarily involve the skull where they are preferentially seen in the sphenoid and temporal bones. In the pediatric age group they are exceptionally rare.
  
  
  METHODS
  The authors report the management of a GCT involving the frontal bone in an 18-month-old girl. The patient underwent wide surgical excision of the lesion and remains free of clinical and radiological evidence of tumoral recurrence thirty months after treatment.
  
  
  CONCLUSIONS
  Although rare, GCTs should be taken into consideration as a differential diagnosis of rapidly enlarging cranial mass lesions in pediatric patients. Gross total surgical excision eliminates the potential risks of adjuvant radiotherapy. However, considering the aggressive nature and potential malignancy of these lesions, careful long-term clinical and imaging follow-up is recommended.
authors.affiliation: Sakarya ToyotaSA State Hospital, Department of Neurosurgery, Sakarya, Turkey. dronurulu@gmail.com
authors.forename: M O
authors.initials: MO
authors.lastname: Ulu
authors.forename: H
authors.initials: H
authors.lastname: Biceroglu
authors.forename: F
authors.initials: F
authors.lastname: Ozlen
authors.forename: B
authors.initials: B
authors.lastname: Oz
authors.forename: N
authors.initials: N
authors.lastname: Gazioglu
mesh_terms: D018572:Disease-Free Survival; D005260:Female; D005624:Frontal Bone / Q000473:pathology* / Q000601:surgery*; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007223:Infant; D013997:Time Factors