title: Does lower birth order amplify the association between high socioeconomic status and central adiposity in young adult Filipino males?
abstract: OBJECTIVE
  To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower income, developing country context.
  
  
  METHODS
  The Cebu Longitudinal Health and Nutrition Survey is an ongoing community-based, observational study of a 1-year birth cohort (1983).
  
  
  METHODS
  970 young adult males, mean age 21.5 years (2005).
  
  
  METHODS
  Central adiposity measured by waist circumference; birth order; perinatal maternal characteristics including height, arm fat area, age and smoking behavior; socioeconomic status at birth and in young adulthood.
  
  
  RESULTS
  Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity. Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order.
  
  
  CONCLUSIONS
  This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.
authors.affiliation: Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, UK. d.l.dahly@leeds.ac.uk
authors.forename: D L
authors.initials: DL
authors.lastname: Dahly
authors.forename: L S
authors.initials: LS
authors.lastname: Adair
mesh_terms: D001722:Birth Order; D001724:Birth Weight / Q000502:physiology*; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009749:Nutrition Surveys; D056128:Obesity, Abdominal / Q000191:economics* / Q000453:epidemiology / Q000209:etiology; D010679:Philippines / Q000453:epidemiology; D011247:Pregnancy; D012923:Social Class; D055815:Young Adult