title: Current guidance on the management of acute coronary syndrome.
abstract: Acute coronary syndrome (ACS) describes a spectrum of symptoms arising from the development of atherosclerosis. The degree of myocardial ischaemia depends on plaque stability and the extent of vessel occlusion. This article examines underlying pathophysiological processes and reviews current guidance and principles of managing ACS through symptom control, reducing mortality and maximizing secondary prevention. Nurses have a vital role in all aspects of delivering this care and meeting National Service Framework Standards for Coronary Heart Diseases (CHD) (2000). A clear understanding of the pathophysiological basis for ACS will reinforce clinical work, particularly in the recognition, monitoring and early management.
authors.affiliation: University of Greenwich, London, UK.
authors.forename: Harry
authors.initials: H
authors.lastname: Chummun
authors.forename: Karina
authors.initials: K
authors.lastname: Gopaul
authors.forename: Anita
authors.initials: A
authors.lastname: Lutchman
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D000368:Aged; D000465:Algorithms; D000925:Anticoagulants / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000379:methods; D009569:Nitric Oxide / Q000627:therapeutic use; D024802:Nurse's Role; D009730:Nursing Assessment; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D055502:Secondary Prevention / Q000379:methods; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents; D009569:Nitric Oxide