[Combination profiles of hepatitis B marks for Chinese in serosurvey in 2006].
OBJECTIVE
To summarize the combination profile of hepatitis B markers by age and immunization history of Chinese.


METHODS
Population of age 1-59 years were sampled from 160 counties of National Disease Surveillance in 31 provinces by multi-stage random sampling method. Demographic information and hepatitis B vaccination history was collected by questionnaire, and 2-4ml serum sample was taken for testing HBsAg, Anti-HBs and Anti-HBc by ELISA method.


RESULTS
16 combinations of hepatitis B markers (HBsAg, Anti-HBs, Anti-HBc, HBeAg and Anti-HBe) were found during the testing, anti-HBs was mainly found among 1-4 years old children, accounted 69.77%. Among 15-59 years, negative markers were mainly profile. Among immunized population, the older, the lower rate of anti-HBs, while among un-immunized population, except negative for all markers and anti-HBs were observed, Infected markers was account for high proportion.


CONCLUSIONS
The profile could be used for guiding the laboratory testing by different epidemiologic characteristics, and can provide information for reference.
Cui
Fu-Qiang
FQ
Department of National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Bi
Sheng-Li
SL
Zhang
Yong
Y
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000097:blood* / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000276:immunology; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D007114:Immunization; D007223:Infant; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D011159:Population Surveillance; D055815:Young Adult
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines