Endometrioid adenocarcinoma arising from endometriosis of the rectosigmoid.
A case of endometrioid adenocarcinoma supposedly arising from endometriosis of the rectum is reported. Malignant transformation is uncommon but a well-known complication of endometriosis. In the present case, it was proved by histopathological findings and immunophenotype such as cytokeratin7+/cytokeratin20-/estrogen receptor+. The cause of rectal endometriosis in this case might have been related with previously received hormone replacement therapy for ovarian endometriosis. Following surgical removal of the lesion, this patient underwent adjuvant chemotherapy with paclitaxel and carboplatin, although this kind of therapy is still controversial as to its effectiveness.
Kobayashi
Shigeru
S
Department of Surgery, Tokyo Rinkai Hospital, Tokyo, Japan. kshigrinkai@yahoo.co.jp
Sasaki
Morio
M
Goto
Tatsuya
T
Asakage
Naoki
N
Sekine
Masayuki
M
Suzuki
Takahisa
T
Tsukada
Kenji
K
Yamasaki
Shigetaka
S
Ukawa
Shiro
S
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D003113:Colonoscopy; D016889:Endometrial Neoplasms / Q000209:etiology* / Q000473:pathology; D004715:Endometriosis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000150:complications; D012002:Rectal Diseases / Q000150:complications* / Q000473:pathology; D012810:Sigmoid Diseases / Q000150:complications* / Q000473:pathology