title: Stress hormones and immunological responses to a dual challenge in professional firefighters.
abstract: The purpose of this study was to examine the changes in heart rate (HR), catecholamines (norepinephrine [NE] and epinephrine [EPI]), pro-inflammatory cytokines (interleukin-2 [IL-2] and interleukin-6 [IL-6]), and lymphocytes (CD8+ and CD56+) in firefighters exposed to a decision-making challenge (firefighting strategies and tactics drill) while participating in moderate intensity exercise. Nine professional male firefighters participated in two counterbalanced exercise conditions on a cycle ergometer: (1) 37 min of cycle ergometry at 60% VO(2max) (exercise alone condition ; EAC) and (2) 37 min of cycle ergometry at 60% VO(2max) along with 20 min of a computerized firefighting strategy and tactics decision-making challenge (firefighting strategy condition; FSC). FSC elicited significantly greater HR, NE, EPI, and IL-2 when compared to EAC. These elevations may suggest that the addition of a mental challenge to physical stress can alter the hormonal and immunological responses during firefighting. In addition, this evidence provides insight into the possible mechanisms that explain the link between physical activity, psychological stress, and stress-related diseases.
authors.affiliation: Florida Atlantic University, Boca Raton, FL, USA. chuang5@fau.edu
authors.forename: Chun-Jung
authors.initials: CJ
authors.lastname: Huang
authors.forename: Heather E
authors.initials: HE
authors.lastname: Webb
authors.forename: Ryan S
authors.initials: RS
authors.lastname: Garten
authors.forename: Gary H
authors.initials: GH
authors.lastname: Kamimori
authors.forename: Ronald K
authors.initials: RK
authors.lastname: Evans
authors.forename: Edmund O
authors.initials: EO
authors.lastname: Acevedo
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D019540:Area Under Curve; D002395:Catecholamines / Q000097:blood; D003198:Computer Simulation; D016207:Cytokines / Q000097:blood; D003657:Decision Making / Q000502:physiology*; D004563:Electrochemistry / Q000379:methods; D015444:Exercise / Q000502:physiology / Q000523:psychology; D005390:Fires; D006339:Heart Rate / Q000502:physiology; D006728:Hormones / Q000097:blood*; D006801:Humans; D007318:Inservice Training; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D010101:Oxygen Consumption; D013315:Stress, Psychological / Q000097:blood / Q000503:physiopathology*
chemical_list: D002395:Catecholamines; D016207:Cytokines; D006728:Hormones