[Developments and applications of multidimensional liquid chromatography in proteomics].
This review summarizes the recent developments of multidimensional liquid chromatography (MDLC) techniques, and their applications in proteomics study, including expression profiling, post-translational modification, quantitative analysis, and so forth. In addition, the prospect and further developments of MDLC are discussed.
Zhu
Guijie
G
National Chromatographic R. & A. Center, CAS Key Laboratory of Separation Science for Analytical Chemist Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Liang
Zhen
Z
Zhang
Lihua
L
Zhang
Yukui
Y
D002853:Chromatography, Liquid / Q000379:methods*; D020869:Gene Expression Profiling; D011499:Protein Processing, Post-Translational; D040901:Proteomics