Gastric ulcer in a child treated with deferasirox.
We present a patient with thalassemia major who developed a gastric ulcer, probably related to the use of deferasirox. Although gastric ulcer is mentioned as infrequent adverse event in the scientific product information of deferasirox, in our current knowledge, this is the first case-report on this adverse drug reaction. The severity of this event justifies the reporting of this case.
Bauters
Tiene
T
Department of Pharmacy, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium. tiene.bauters@uzgent.be
Mondelaers
Veerle
V
Robays
Hugo
H
Hunninck
Kathleen
K
de Moerloose
Barbara
B
D001565:Benzoates / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D000077588:Deferasirox; D005260:Female; D006801:Humans; D007502:Iron Chelating Agents / Q000009:adverse effects* / Q000627:therapeutic use; D013276:Stomach Ulcer / Q000139:chemically induced*; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use; D017086:beta-Thalassemia / Q000188:drug therapy
D001565:Benzoates; D007502:Iron Chelating Agents; D014230:Triazoles; D000077588:Deferasirox