title: History, molecular mechanisms, and endoscopic treatment of Barrett's esophagus.
abstract: This report is an adjunct to the American Gastroenterological Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future. Those documents will consider a number of broad questions on the diagnosis, clinical features, and management of patients with Barrett's esophagus, and the reader is referred to the technical review for an in-depth discussion of those topics. In this report, we review historical, molecular, and endoscopic therapeutic aspects of Barrett's esophagus that are of interest to clinicians and researchers.
authors.affiliation: VA North Texas Healthcare System and The University of Texas Southwestern Medical Center, Dallas, Texas, USA. sjspechler@aol.com
authors.forename: Stuart Jon
authors.initials: SJ
authors.lastname: Spechler
authors.forename: Rebecca C
authors.initials: RC
authors.lastname: Fitzgerald
authors.forename: Ganapathy A
authors.initials: GA
authors.lastname: Prasad
authors.forename: Kenneth K
authors.initials: KK
authors.lastname: Wang
mesh_terms: D001471:Barrett Esophagus / Q000209:etiology / Q000266:history / Q000473:pathology / Q000628:therapy*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D004938:Esophageal Neoplasms / Q000266:history / Q000473:pathology / Q000628:therapy*; D004945:Esophagoscopy / Q000266:history / Q000379:methods; D004947:Esophagus / Q000473:pathology*; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008679:Metaplasia; D011230:Precancerous Conditions / Q000209:etiology / Q000266:history / Q000473:pathology / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome