Rhodium-catalyzed asymmetric reductive cyclization of heteroatom-linked 5-alkynals with heteroatom-substituted acetaldehydes.
We have established that a cationic rhodium(I)/H(8)-BINAP complex catalyzes the asymmetric reductive cyclization of heteroatom-linked 5-alkynals with heteroatom-substituted acetaldehydes in good yields with outstanding enantioselectivity.
Tanaka
Rie
R
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan.
Noguchi
Keiichi
K
Tanaka
Ken
K