title: Cross-couplings between benzylic and aryl halides "on water": synthesis of diarylmethanes.
abstract: A remarkably simple entry to unsymmetrical diarylmethanes has been developed that relies on an in situ organozinc-mediated, palladium-catalyzed cross-coupling. Thus, by mixing a benzyl and aryl halide together in the presence of Zn metal and a Pd catalyst, diarylmethanes are formed at room temperature without assistance by a surfactant; hence, "on water".
authors.affiliation: Department of Chemistry & Biochemistry, University of California, Santa Barbara, CA 93106, USA.
authors.forename: Christophe
authors.initials: C
authors.lastname: Duplais
authors.forename: Arkady
authors.initials: A
authors.lastname: Krasovskiy
authors.forename: Alina
authors.initials: A
authors.lastname: Wattenberg
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
mesh_terms: D002384:Catalysis; D006219:Halogens / Q000138:chemical synthesis / Q000737:chemistry; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000737:chemistry
chemical_list: D006219:Halogens; D006841:Hydrocarbons, Aromatic; D014867:Water; D010165:Palladium; D015032:Zinc; D008697:Methane