Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease.
Tolar
Jakub
J
Eapen
Mary
M
Orchard
Paul J
PJ
Blazar
Bruce R
BR
D000818:Animals; D017209:Apoptosis / Q000276:immunology*; D016026:Bone Marrow Transplantation; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D002462:Cell Membrane / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D002518:Ceramides / Q000276:immunology*; D016207:Cytokines / Q000378:metabolism; D004195:Disease Models, Animal; D005260:Female; D006086:Graft vs Host Disease / Q000276:immunology* / Q000473:pathology; D022781:Hepatocytes / Q000276:immunology / Q000378:metabolism; D007371:Interferon-gamma / Q000378:metabolism; D007421:Intestine, Small / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D008213:Lymphocyte Activation; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D019463:Mice, Inbred MRL lpr; D016513:Mice, SCID; D012867:Skin / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D013108:Sphingomyelin Phosphodiesterase / Q000502:physiology*; D015996:Survival Rate
D002518:Ceramides; D016207:Cytokines; D007371:Interferon-gamma; C112980:acid sphingomyelinase-1; D013108:Sphingomyelin Phosphodiesterase