title: Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia.
abstract: Phytochemical investigation of the methanol extract of Tinospora cordifolia aerial parts led to the isolation of four new and seven known compounds. The structures of two new aporphine alkaloids, N-formylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside A, 1) and N-acetylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside B, 2), a new clerodane diterpene, tinoscorside C (3), and a new phenylpropanoid, sinapyl 4-O-beta-D-apiofuranosyl-(1-->6)-O-beta-D-glucopyranoside (tinoscorside D, 6) were determined by extensive spectroscopic methods including FTICR-MS and 1D and 2D NMR.
authors.affiliation: Laboratory of Organic Chemistry, Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam. phankiem@vast.ac.vn
authors.forename: Van Kiem
authors.initials: VK
authors.lastname: Phan
authors.forename: Van Minh
authors.initials: VM
authors.lastname: Chau
authors.forename: Tien Dat
authors.initials: TD
authors.lastname: Nguyen
authors.forename: Van Kinh
authors.initials: VK
authors.lastname: La
authors.forename: Thuy Hang
authors.initials: TH
authors.lastname: Dan
authors.forename: Hoai Nam
authors.initials: HN
authors.lastname: Nguyen
authors.forename: Xuan Cuong
authors.initials: XC
authors.lastname: Nguyen
authors.forename: Thanh Huong
authors.initials: TH
authors.lastname: Hoang
authors.forename: Van Lau
authors.initials: VL
authors.lastname: Trinh
mesh_terms: D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000302:isolation & purification; D015394:Molecular Structure; D010666:Phenylpropionates / Q000302:isolation & purification; D031610:Tinospora / Q000737:chemistry*
chemical_list: D001060:Aporphines; D045785:Diterpenes, Clerodane; D005960:Glucosides; D010666:Phenylpropionates; C028305:syringin