Disseminated cutaneous and visceral Kaposi sarcoma in a woman with rheumatoid arthritis receiving leflunomide.
Kaposi sarcoma (KS) is a vascular neoplasm mainly affecting the skin of the limbs that has previously been associated with rheumatoid arthritis (RA). When compared with the RA patients treated with corticosteroids and immunosuppressive drugs, the reported number of KS in RA patients was very rare. Although the exact mechanisms of developing KS in RA patients are unclear, some drugs which include corticosteroid have been suggested as an etiological factor in previous case reports of RA and KS. We report, here in, another case of KS associated with the initiation of leflunomide in a patient with RA.
Lee
Sang Yeob
SY
Department of Internal Medicine, College of Medicine, Dong-A University, Pusan, Korea.
Jo
Yong Min
YM
Chung
Won Tae
WT
Kim
Sung Hyun
SH
Kim
Seung Young
SY
Roh
Mee Sook
MS
Lee
Sung Won
SW
D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects* / Q000627:therapeutic use; D000077339:Leflunomide; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000139:chemically induced*
D018501:Antirheumatic Agents; D007555:Isoxazoles; D000077339:Leflunomide