The NDE1 gene is disrupted by the inv(16) in 90% of cases with CBFB-MYH11-positive acute myeloid leukemia.
Van der Reijden
B A
BA
Massop
M
M
Simons
A
A
de Witte
T
T
Breuning
M
M
Jansen
J H
JH
D007446:Chromosome Inversion; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D008869:Microtubule-Associated Proteins / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction
C095514:CBFbeta-MYH11 fusion protein; D008869:Microtubule-Associated Proteins; C525094:Nde1 protein, human; D015514:Oncogene Proteins, Fusion; D012333:RNA, Messenger