title: [Local recurrence in soft tissue sarcoma: prognostic factors].
abstract: OBJECTIVE
  To determinate the prognostic factors associated with the local relapse in patients treated for soft tissue sarcoma in extremities.
  
  
  METHODS
  Retrospectively, 30 patients were evaluated after being treated with surgical resection of soft tissue sarcoma located in extremities, with a outcome of 36,5 +/- 12,2 months. The prognostic factors evaluated were: age, sex, location, depth, location in the anatomic compartments, size, tumor previous manipulation, surgical margins, grade of histological malignance, presence of histological necrosis or histological vascular invasion. These factors were correlated with the local relapse of the tumor with a univariated and multivariated analysis with significance when p = 0,05.
  
  
  RESULTS
  Local relapse presented significant correlation in univariated and multivariated analysis with extra-compartimental location (p = 0,001) and with high grade histological malignance (p = 0,001). There was no significant association with age (p = 1,000), sex (p = 1,000), body location (p = 0,544), depth (p = 0,288), size (p = 0,694), surgical margins (p = 0,384), previous manipulation (p = 0,461), necrosis (p = 0,461) or with the presence of vascular invasion (p = 1,000).
  
  
  CONCLUSIONS
  Local relapse presents correlation with extra-compartimental location and with high grade malignancy tumors.
authors.affiliation: Ambulatório de Oncologia Ortopédica do Hospital das Clínicas da Universidade Federal de Minas Gerais - UFMG e no Biocor Instituto, Belo Horizonte, MG, Brasil. luizmteixeira@yahoo.com.br
authors.forename: Luiz Eduardo Moreira
authors.initials: LE
authors.lastname: Teixeira
authors.forename: Ivana Duval
authors.initials: ID
authors.lastname: Araújo
authors.forename: Marco Antônio Percope
authors.initials: MA
authors.lastname: de Andrade
authors.forename: Rogério Andrade
authors.initials: RA
authors.lastname: Gomes
authors.forename: Paulo Guilherme de Oliveira
authors.initials: PG
authors.lastname: Salles
authors.forename: Daniel Ferreira
authors.initials: DF
authors.lastname: Ghedini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012509:Sarcoma / Q000453:epidemiology*; D012983:Soft Tissue Neoplasms / Q000453:epidemiology*; D055815:Young Adult