title: Multi-detector row CT as a "one-stop" examination in the preoperative evaluation of the morphology and function of living renal donors: preliminary study.
abstract: We designed to investigate the feasibility of multi-detector row computerized tomography (CT) as a "one-stop" examination for the simultaneous preoperative evaluation of the morphology and function of living renal donors. 21 living renal donors were examined by 64-slice spiral CT with a three-phase enhancement CT scan and two inserted dynamic scans. The maximum intensity projection (MIP), multi-planar reformation (MPR), and volume reconstruction (VR) procedures were performed to compare the renal parenchyma, renal vessels, and collecting system with operational findings. The known Patlak equation was used to calculate the glomerular filtration rate (GFR); exact GFR information was acquired by single photon emission computed tomography (SPECT). Our results as following, there were 3 cases of artery variation and 3 cases of vein variation. CT findings all corresponded with the operation, and the sensitivity, positive predictive value, specialty, and negative predictive value of CT were all 100%. The r of the GFR values estimated from CT is 0.894 (left) (P < 0.001) and 0.881 (right) (P < 0.001). In conclusions, our findings demonstrate that 64-slice spiral CT may offer a "one-stop" examination to replace SPECT in the preoperative evaluation of living renal donors to simultaneously provide information regarding both anatomy and the GFR of living renal donors.
authors.affiliation: Department of Radiology, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Su
authors.forename: Chaogui
authors.initials: C
authors.lastname: Yan
authors.forename: Yan
authors.initials: Y
authors.lastname: Guo
authors.forename: Xuhui
authors.initials: X
authors.lastname: Zhou
authors.forename: Yaqing
authors.initials: Y
authors.lastname: Chen
authors.forename: Mingjuan
authors.initials: M
authors.lastname: Liu
authors.forename: Wenjuan
authors.initials: W
authors.lastname: Wang
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging*; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D036542:Tomography, Spiral Computed / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media