title: DBH deficiency in an elderly patient: efficacy and safety of chronic droxidopa.
abstract: We describe the effects of chronic droxidopa in a patient with Dopamine beta-hydroxylase deficiency diagnosed at the age of 73. Investigations were performed to assess sympathetic activity (MIBG scintigraphy, catecholamines) and cardiovascular droxidopa safety.
authors.affiliation: INSERM U858 équipe 8, 31432 Toulouse, France. fabien.despas@yahoo.fr
authors.forename: Fabien
authors.initials: F
authors.lastname: Despas
authors.forename: A
authors.initials: A
authors.lastname: Pathak
authors.forename: M
authors.initials: M
authors.lastname: Berry
authors.forename: R
authors.initials: R
authors.lastname: Cagnac
authors.forename: P
authors.initials: P
authors.lastname: Massabuau
authors.forename: E
authors.initials: E
authors.lastname: Liozon
authors.forename: M
authors.initials: M
authors.lastname: Galinier
authors.forename: J M
authors.initials: JM
authors.lastname: Senard
mesh_terms: D019797:3-Iodobenzylguanidine; D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000201:enzymology*; D002395:Catecholamines / Q000097:blood; D004299:Dopamine beta-Hydroxylase / Q000172:deficiency*; D015103:Droxidopa / Q000627:therapeutic use*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D002395:Catecholamines; D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine; D004299:Dopamine beta-Hydroxylase; D015103:Droxidopa