title: Assessment of vision and hearing in children conceived spontaneously and by ICSI: a prospective controlled, single-blinded follow-up study.
abstract: Long-term follow-up studies on the health of children born after assisted reproduction technologies are mandatory. Vision and hearing are the most important senses that continue to develop during childhood. There are few reports on vision and hearing in preschool children born after assisted conception. This prospective controlled blinded follow-up study examined 276 term-born singleton intracytoplasmic injection (ICSI) children and 273 spontaneously conceived controls at a mean age of 5.5 years and performed detailed vision and hearing test and clinically examined eyes and ears. There was no significant difference between ICSI and control children regarding the occurrence of vision or hearing impairments. Unsurprisingly, children with abnormalities in otoscopy were more likely to have an abnormal hearing test compared with children without abnormalities. Only 8.5% of ICSI parents and 25.4% of control parents whose children showed an abnormal hearing test knew about the hearing problems of their child. In conclusion, there was no difference in the development of hearing and vision in ICSI children and spontaneously conceived controls. But only few parents knew about hearing problems of their child after undergoing routine screening examinations. Parental interviews would therefore not be sufficient in order to assess vision and hearing in follow-up studies.
authors.affiliation: Zentrum für Hormon- und Stoffwechselerkrankungen, Reproduktionsmedizin und Pränatale Medizin, Endokrinologikum Hamburg, Lornsenstr 4-6, 22767 Hamburg, Germany. A.K.Ludwig@web.de
authors.forename: A K
authors.initials: AK
authors.lastname: Ludwig
authors.forename: A
authors.initials: A
authors.lastname: Hansen
authors.forename: A
authors.initials: A
authors.lastname: Katalinic
authors.forename: A G
authors.initials: AG
authors.lastname: Sutcliffe
authors.forename: K
authors.initials: K
authors.lastname: Diedrich
authors.forename: M
authors.initials: M
authors.lastname: Ludwig
authors.forename: Ute
authors.initials: U
authors.lastname: Thyen
mesh_terms: D002648:Child; D005500:Follow-Up Studies; D006309:Hearing; D006801:Humans; D008137:Longitudinal Studies; D011446:Prospective Studies; D016037:Single-Blind Method; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects; D014785:Vision, Ocular