Systemic loxoscelism confirmation by bite-site skin surface: ELISA.
We report here a case of systemic loxoscelism, confirmed by bite-site skin surface swab. Features of systemic loxoscelism present in this case included debilitating symptoms, a classic local bite-site reaction, hemolysis causing loss of approximately 15% of the blood volume within 72 hours, and a symptomatic exanthem. A skin surface ELISA test was used to confirm the presence of venom. This test enables confirmation of cases of loxoscelism for which no spider is found.
Stoecker
William V
WV
Division of Dermatology, University of Missouri School of Medicine, MO, USA. wvs@mst.edu
Wasserman
Gary S
GS
Calcara
David A
DA
Green
Jonathan A
JA
Larkin
Karen
K
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D054796:Drug Dosage Calculations; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010727:Phosphoric Diester Hydrolases / Q000032:analysis*; D001098:Spider Bites / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D013111:Spider Venoms / Q000032:analysis*
D000305:Adrenal Cortex Hormones; D013111:Spider Venoms; C055161:loxosceles venom; D010727:Phosphoric Diester Hydrolases