PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.
In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.
Ruepp
Andreas
A
Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@helmholtz-muenchen.de
Kowarsch
Andreas
A
Schmidl
Daniel
D
Buggenthin
Felix
F
Brauner
Barbara
B
Dunger
Irmtraud
I
Fobo
Gisela
G
Frishman
Goar
G
Montrone
Corinna
C
Theis
Fabian J
FJ
D000465:Algorithms; D001671:Biochemistry / Q000379:methods; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods*; D004194:Disease / Q000235:genetics; D020869:Gene Expression Profiling; D005796:Genes; D016678:Genome; D006801:Humans; D020407:Internet; D008126:Lod Score; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D008954:Models, Biological; D008957:Models, Genetic
D035683:MicroRNAs