title: The overlap of systemic lupus erythematosus and sickle cell disease: report of two cases and a review of the literature.
abstract: Two cases of Afro-Caribbean women with an association of sickle cell disease (SCD) and systemic lupus erythematosus (SLE) are presented. We discuss the clues to the diagnosis of this combination with a review of the literature. Owing to a substantial overlap between the clinical manifestations of the two disorders, the diagnosis of SLE in patients with SCD may be difficult to establish and is often delayed.
authors.affiliation: Department of Internal Medicine, Hospital Universitario La Fe, Spain. marcelacherner@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Cherner
authors.forename: D
authors.initials: D
authors.lastname: Isenberg
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D044383:Black People; D017691:Caribbean Region; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged