High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex.
A novel dinuclear ruthenium(II) complex with high fluorescent selectivity between DNA quadruplex structures and duplex structures was generated, and using an iodide-quenching strategy, G-quadruplex structures can be easily distinguished from duplex structures by the naked eye.
Xu
Liang
L
College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Hubei, Wuhan, 430072, P. R. China.
Zhang
Dan
D
Huang
Jing
J
Deng
Minggang
M
Zhang
Ming
M
Zhou
Xiang
X
D005453:Fluorescence; D054856:G-Quadruplexes; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
D009942:Organometallic Compounds; D012428:Ruthenium