Making cellular memories.
The induction of a protracted response to a brief stimulus is a form of cellular memory. Here we describe the role of transcriptional regulation in both natural and synthetic memory networks and discuss the potential applications of engineered memory networks in medicine and industrial biotechnology.
Burrill
Devin R
DR
Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
Silver
Pamela A
PA
D000818:Animals; D001419:Bacteria / Q000235:genetics; D002468:Cell Physiological Phenomena; D005786:Gene Expression Regulation; D053263:Gene Regulatory Networks; D005818:Genetic Engineering; D007156:Immunologic Memory; D009876:Operon; D014158:Transcription, Genetic