title: Lights on iron-sulfur clusters.
abstract: The biogenesis of iron-sulfur proteins within a living cell is traditionally investigated by enzyme activity measurements and radiolabeling techniques. In this issue of Chemistry and Biology, Hoff et al. introduce a non-invasive fluorescence-based method to trace the formation of iron-sulfur clusters at high sensitivity.
authors.affiliation: Institut für Zytobiologie und Zytopathologie, Philipps-Universität Marburg, Robert-Koch-Strasse 6, 35032 Marburg, Germany.
authors.forename: Christopher Horst
authors.initials: CH
authors.lastname: Lillig
authors.forename: Roland
authors.initials: R
authors.lastname: Lill
mesh_terms: D002460:Cell Line; D019281:Dimerization; D054477:Glutaredoxins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000737:chemistry*; D008164:Luminescent Proteins / Q000737:chemistry / Q000378:metabolism; D008856:Microscopy, Fluorescence; D009154:Mutation; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D013455:Sulfur / Q000737:chemistry*
chemical_list: C516008:GLRX2 protein, human; D054477:Glutaredoxins; D008164:Luminescent Proteins; D011993:Recombinant Fusion Proteins; D013455:Sulfur; D007501:Iron