title: Mechanical ventilation in trauma.
abstract: OBJECTIVE
  The purpose of this review is to evaluate new concepts in mechanical ventilation in trauma. We begin with the keystone of physiology prior to embarking on a discussion of several new modes of mechanical ventilation. We will discuss the use of noninvasive ventilation as a mode to prevent intubation and then go on to airway pressure release ventilation, high-frequency oscillatory ventilation, and computer-based, closed loop ventilation.
  
  
  RESULTS
  The importance of preventing further injury in mechanical ventilation lies at the heart of the introduction of several new strategies of mechanical ventilation. New modes of ventilation have been developed to provide lung recruitment and alveolar stabilization at the lowest possible pressure.
  
  
  CONCLUSIONS
  The old modes of continuous positive airway pressure and bilevel positive airway pressure have been actively introduced in clinical practice in the case of trauma patients. Used with proper pain management protocols, there has been a decrease in the incidence of intubation in blunt thoracic trauma. Airway pressure release ventilation has been gaining a role in the management of thoracic injury and may lead to less incidence of physiologic trauma to mechanically ventilated patients. High-frequency oscillatory ventilation has been shown to be effective in patient care by its ability to open and recruit the lung in trauma patients and in those with acute respiratory distress syndrome but it may not have a role in patients with inhalational injury. Closed loop ventilation is a technology that may better control major pulmonary parameters and lead to more rapid titration from the ventilator to spontaneous breathing.
authors.affiliation: Department of Anesthesiology, Surgery and Neurosurgery, USA. Peter_Papadakos@URMC.Rochester.edu
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Papadakos
authors.forename: Marcin
authors.initials: M
authors.lastname: Karcz
authors.forename: Burkhard
authors.initials: B
authors.lastname: Lachmann
mesh_terms: D006801:Humans; D012121:Respiration, Artificial; D012143:Respiratory Physiological Phenomena; D012122:Ventilators, Mechanical; D014947:Wounds and Injuries / Q000503:physiopathology / Q000628:therapy*