title: Blue fluorescent deoxycytidine analogues: convergent synthesis, solid-state and electronic structure, and solvatochromism.
abstract: We report the synthesis and photospectroscopic characterisation of intrinsically fluorescent triazole-appended cytidines. Fluorescence was found to be highly dependent on solvent conditions. X-Ray crystallographic data show the proton of the exocyclic amine of the nucleobase and the triazole N(3) engaged in a H-bond.
authors.affiliation: Department of Chemistry, The University of Western Ontario, London, Ontario, Canada N6A 5B7.
authors.forename: David W
authors.initials: DW
authors.lastname: Dodd
authors.forename: Kalen N
authors.initials: KN
authors.lastname: Swanick
authors.forename: Jacquelyn T
authors.initials: JT
authors.lastname: Price
authors.forename: Allison L
authors.initials: AL
authors.lastname: Brazeau
authors.forename: M J
authors.initials: MJ
authors.lastname: Ferguson
authors.forename: Nathan D
authors.initials: ND
authors.lastname: Jones
authors.forename: Robert H E
authors.initials: RH
authors.lastname: Hudson
mesh_terms: D003116:Color; D018360:Crystallography, X-Ray; D003841:Deoxycytidine / Q000138:chemical synthesis / Q000737:chemistry*; D004583:Electrons; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008163:Luminescent Measurements; D008958:Models, Molecular; D008968:Molecular Conformation; D009696:Nucleic Acids / Q000737:chemistry; D011789:Quantum Theory; D012997:Solvents / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D009696:Nucleic Acids; D012997:Solvents; D003841:Deoxycytidine