title: Manic spectrum symptoms are correlated to the severity of pain and the health-related quality of life in patients with fibromyalgia.
abstract: OBJECTIVE
  We aimed at investigating the impact of lifetime manic spectrum symptoms on the severity of pain and the health-related quality of life (HRQoL) in patients with fibromyalgia (FM).
  
  
  METHODS
  One hundred and sixty-seven patients with FM, assessed according to the ACR criteria, were consecutively enrolled. Psychiatric diagnoses were carried out following the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV-TR). The severity of pain and the HRQoL of FM patients was measured by means of the Fibromyalgia Impact Questionnaire (FIQ) and the Medical Outcomes Study Short Form-36 Health Survey (MOS SF-36); the mood spectrum symptomatology by means of the Mood Spectrum-Self Report (MOODS-SR).
  
  
  RESULTS
  A high rate of lifetime manic symptoms was detected and resulted as related to the Pain Visual Analogic Scale ("pain VAS") of the FIQ and the FIQ total scores as well as to the "bodily pain", and to the physical and mental component summary scores of the MOS SF-36, both in the whole sample (n=167) and in FM patients without bipolar disorder (n=160).
  
  
  CONCLUSIONS
  Our results highlight the need to pay more attention to manic spectrum symptoms and features in FM patients, because of their relationship with the severity of pain and with a worse HRQoL.
authors.affiliation: Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Dell'Osso
authors.forename: L
authors.initials: L
authors.lastname: Bazzichi
authors.forename: G
authors.initials: G
authors.lastname: Consoli
authors.forename: C
authors.initials: C
authors.lastname: Carmassi
authors.forename: M
authors.initials: M
authors.lastname: Carlini
authors.forename: E
authors.initials: E
authors.lastname: Massimetti
authors.forename: C
authors.initials: C
authors.lastname: Giacomelli
authors.forename: S
authors.initials: S
authors.lastname: Bombardieri
authors.forename: A
authors.initials: A
authors.lastname: Ciapparelli
mesh_terms: D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000150:complications / Q000175:diagnosis*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005356:Fibromyalgia / Q000150:complications / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000150:complications / Q000523:psychology*; D010147:Pain Measurement; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires