[Establishment of hepatitis B virus marker panels].
OBJECTIVE
To establish HBV marker panels.


METHODS
155 blood plasma specimens were selected and each was detected twice for 5 HBV markers with MEIA kits made by Abbott. Any plasma that had 2 positive or negative results were enrolled in the HBV marker panels and others were excluded.


RESULTS
153 plasma were enrolled in the HBsAg panel and 154 were enrolled in anti-HBs, anti-HBc and anti-HBe panels respectively. Panel of HBeAg was not established because that there were only 4 positives.


CONCLUSIONS
HBV marker panels can be established by screening enough blood plasma specimens with high accurate kits for more than one time. The panels should be used in a limited extension to avoid unnecessary mistakes.
Zhang
Yong
Y
State Key Laboratory for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing 100052, China.
Wang
Feng
F
Ma
Jing-Chen
JC
D015415:Biomarkers / Q000097:blood; D006508:Hepatitis Antibodies / Q000097:blood* / Q000276:immunology; D006509:Hepatitis B / Q000097:blood* / Q000276:immunology / Q000821:virology; D006515:Hepatitis B virus / Q000737:chemistry* / Q000276:immunology; D006801:Humans; D011933:Reagent Kits, Diagnostic
D015415:Biomarkers; D006508:Hepatitis Antibodies; D011933:Reagent Kits, Diagnostic