title: Severe renal failure in acute bacterial pyelonephritis: do not forget corticosteroids.
abstract: Acute renal failure (ARF) is a rare complication of acute pyelonephritis in adult immunocompetent patients. Recovery of renal function usually occurs if antibiotics are promptly initiated. However, long-term consequences of renal scarring due to acute pyelonephritis are probably underestimated, and some patients present with prolonged renal failure despite adequate antibiotic therapy. We report two cases of severe ARF complicating bacterial pyelonephritis successfully treated with corticosteroids in association with conventional antibiotics.
authors.affiliation: Department of Nephrology, AP-HP, Hopital Necker, Universite Paris V, Paris, France. tariksqalli@hotmail.com
authors.forename: Tarik Houssaini
authors.initials: TH
authors.lastname: Sqalli
authors.forename: Hakim
authors.initials: H
authors.lastname: Hamzaoui
authors.forename: Elsa
authors.initials: E
authors.lastname: Guiard
authors.forename: Laure-Helene
authors.initials: LH
authors.lastname: Noel
authors.forename: Fadi
authors.initials: F
authors.lastname: Fakhouri
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011513:Proteus mirabilis / Q000302:isolation & purification; D011704:Pyelonephritis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents