title: Omega-3 polyunsaturated fatty acids affect sirolimus exposure in kidney transplant recipients on calcineurin inhibitor-free regimen.
authors.forename: Monica
authors.initials: M
authors.lastname: Cortinovis
authors.forename: Eliana
authors.initials: E
authors.lastname: Gotti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Remuzzi
authors.forename: Norberto
authors.initials: N
authors.lastname: Perico
authors.forename: Dario
authors.initials: D
authors.lastname: Cattaneo
authors.forename: Sara
authors.initials: S
authors.lastname: Baldelli
mesh_terms: D051544:Cytochrome P-450 CYP3A; D065692:Cytochrome P-450 CYP3A Inhibitors; D004359:Drug Therapy, Combination; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D005231:Fatty Acids, Unsaturated / Q000627:therapeutic use*; D006801:Humans; D015228:Hypertriglyceridemia / Q000139:chemically induced / Q000517:prevention & control*; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D011494:Protein Kinases / Q000009:adverse effects; D012189:Retrospective Studies; D020123:Sirolimus / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D058570:TOR Serine-Threonine Kinases
chemical_list: D065692:Cytochrome P-450 CYP3A Inhibitors; D015525:Fatty Acids, Omega-3; D005231:Fatty Acids, Unsaturated; D007166:Immunosuppressive Agents; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D011494:Protein Kinases; C546842:MTOR protein, human; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus