title: Neopentylglycolborylation of aryl mesylates and tosylates catalyzed by Ni-based mixed-ligand systems activated with Zn.
abstract: The mixed-ligand system NiCl(2)(dppp)/dppf is shown to be an effective catalyst for the neopentylglycolborylation of ortho-, meta-, and para-substituted electron-rich and electron-deficient aryl mesylates and tosylates. The addition of Zn powder as a reductant dramatically increases the reaction yield and reduces the reaction time by more than an order of magnitude, providing complete conversion in 1-3 h.
authors.affiliation: Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA.
authors.forename: Daniela A
authors.initials: DA
authors.lastname: Wilson
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Wilson
authors.forename: Costel
authors.initials: C
authors.lastname: Moldoveanu
authors.forename: Ana-Maria
authors.initials: AM
authors.lastname: Resmerita
authors.forename: Patrick
authors.initials: P
authors.lastname: Corcoran
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Hoang
authors.forename: Brad M
authors.initials: BM
authors.lastname: Rosen
authors.forename: Virgil
authors.initials: V
authors.lastname: Percec
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D008698:Mesylates / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry; D014105:Tosyl Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D001897:Boronic Acids; D008024:Ligands; D008698:Mesylates; D009942:Organometallic Compounds; D014105:Tosyl Compounds; D009532:Nickel; D015032:Zinc