title: Fecal egg counts after anthelmintic administration to aged horses and horses with pituitary pars intermedia dysfunction.
abstract: OBJECTIVE
  To determine effects of pituitary pars intermedia dysfunction (Cushing's disease) and age on fecal egg count and time to egg reappearance after anthelmintic treatment in horses residing in similar environments.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  29 healthy horses (4 to 35 years old) and 13 horses with PPID (13 to 33 years old).
  
  
  METHODS
  Fecal egg counts were performed by use of a modified Wisconsin flotation method at 2-week intervals before and after ivermectin treatment.
  
  
  RESULTS
  Horses with PPID had higher fecal egg counts before and 8, 10, and 12 weeks after ivermectin treatment, compared with counts for site-matched healthy horses. There was no difference in the period for < 90% reduction in fecal egg counts between the 2 groups. Age did not affect fecal egg counts at any time point.
  
  
  CONCLUSIONS
  For similar environmental conditions, horses with PPID were more likely to have higher fecal egg counts than were healthy horses. Therefore, horses with PPID may need to have a more aggressive parasite prevention program than do healthy horses. Age did not affect fecal egg counts or time to egg reappearance after anthelmintic treatment, which suggested age alone does not likely require special consideration when designing a parasite control program for adult horses.
authors.affiliation: Department of Physiological Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
authors.forename: Dianne
authors.initials: D
authors.lastname: McFarlane
authors.forename: Grace M
authors.initials: GM
authors.lastname: Hale
authors.forename: Eileen M
authors.initials: EM
authors.lastname: Johnson
authors.forename: Lara K
authors.initials: LK
authors.lastname: Maxwell
mesh_terms: D000375:Aging; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D005260:Female; D006374:Helminthiasis, Animal / Q000188:drug therapy* / Q000469:parasitology; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology; D006736:Horses; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary; D010900:Pituitary Diseases / Q000150:complications / Q000662:veterinary*; D052716:Pituitary Gland, Intermediate; D013997:Time Factors
chemical_list: D000871:Anthelmintics