Long term survival of primary skeletal muscle lymphoma in a miniature dachshund.
An 8-year-old miniature dachshund presented with a right femoral muscle mass and anorexia. Cytology of the mass revealed a number of small-sized lymphoid cells containing a pleomorphic-shaped dense nucleus and narrow pale cytoplasm. Histopathology indicated that neoplastic lymphoid cells proliferated in skeletal muscles and replaced the muscular architecture. Immunohistochemical and genetic examinations confirmed the diagnosis of primary skeletal muscle lymphoma classified as the pleomorphic small cell type and T-cell low-grade. Although the dog suffered at least three relapses by combination chemotherapy, the dog survived 713 days after the initial presentation.
Takeuchi
Yoshinori
Y
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Fujino
Yasuhito
Y
Goto-Koshino
Yuko
Y
Ohno
Koichi
K
Uchida
Kazuyuki
K
Nakayama
Hiroyuki
H
Tsujimoto
Hajime
H
D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D001215:Asparaginase / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004285:Dogs; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008558:Melphalan / Q000008:administration & dosage; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D010052:Ovariectomy; D011239:Prednisolone / Q000627:therapeutic use; D017741:Survivors; D014057:Tomography, X-Ray Computed
D003606:Dacarbazine; D011239:Prednisolone; D001215:Asparaginase; D008558:Melphalan