title: The effect of left heart bypass on pulmonary blood flow and arterial oxygenation during one-lung ventilation in patients undergoing descending thoracic aortic surgery.
abstract: OBJECTIVE
  To study the effect of left heart bypass (LHB) on regional pulmonary blood flow and arterial oxygenation during one-lung ventilation (OLV).
  
  
  METHODS
  Prospective, observational study
  
  
  METHODS
  Operating room
  
  
  METHODS
  14 ASA physical status II and III patients scheduled to undergo descending thoracic or thoracoabdominal aortic surgery using LHB.
  
  
  METHODS
  Parameters studied during OLV with 100% oxygen before and during LHB mean arterial pressure, heart rate, pulmonary artery pressure, pulmonary capillary wedge pressure, central venous pressure, cardiac index, cardiac output, arterial oxygen tension (PaO(2)), mixed venous oxygen pressure, alveolar arterial oxygen difference (P((A-a)O2)), and right upper pulmonary venous flow (RUPVF). Right upper pulmonary venous flow was measured using transesophageal echocardiography.
  
  
  RESULTS
  With the transition to OLV, there was a significant decrease in PaO(2) and a significant increase in P((A-a)O2). However once LHB was initiated, these values improved significantly (P = 0.0007 and 0.0004, respectively) with the simultaneous increase in RUPVF (P = 0.0018).
  
  
  CONCLUSIONS
  LHB improved pulmonary blood flow to the dependent lung and arterial oxygenation during OLV in descending thoracic aortic surgery.
authors.affiliation: Department of Anesthesiology, Itabashi Chuo Medical Center, Itabashi-ku, Tokyo, Japan. yuki.koichi@gmail.com
authors.forename: Koichi
authors.initials: K
authors.lastname: Yuki
authors.forename: Chieko
authors.initials: C
authors.lastname: Sakuramoto
authors.forename: Chieko
authors.initials: C
authors.lastname: Matsumoto
authors.forename: Mariko
authors.initials: M
authors.lastname: Hoshino
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Niimi
mesh_terms: D000368:Aged; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D001783:Blood Flow Velocity; D004562:Electrocardiography; D005260:Female; D018611:Heart Bypass, Left / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood*; D011446:Prospective Studies; D011651:Pulmonary Artery / Q000502:physiology*; D012039:Regional Blood Flow; D012121:Respiration, Artificial / Q000379:methods*; D012129:Respiratory Function Tests; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D010100:Oxygen