title: Insulin-sensitivity response to a single bout of resistive exercise in type 1 diabetes mellitus.
abstract: BACKGROUND
  Little is known about the acute effects of resistance exercise on insulin sensitivity in people with type 1 diabetes.
  
  
  METHODS
  Repeated-measures design with 2 independent variables: group (exercise and nonexercise control) and time (preexercise and 12 and 36 h postexercise).
  
  
  METHODS
  General Clinical Research Center, Temple University Hospital, Philadelphia, PA.
  
  
  METHODS
  14 physically active subjects (11 men and 3 women) with type 1 diabetes.
  
  
  METHODS
  The exercise group completed 5 sets of 6 repetitions of strenuous (80% 1-RM) quadriceps and hamstring exercises while the control group performed only activities of daily living.
  
  
  METHODS
  Insulin sensitivity was assessed with the euglycemic-hyperinsulinemic-clamp technique preexercise and 12 and 36 h postexercise.
  
  
  RESULTS
  Insulin-sensitivity values were not significantly different between the exercise and control groups (P = .92) or over time (P = .67).
  
  
  CONCLUSIONS
  A single bout of strenuous resistance exercise does not alter insulin sensitivity in people with type 1 diabetes.
authors.affiliation: Dept of Sports Medicine, West Chester University, West Chester, PA, USA.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Jimenez
authors.forename: Mayra
authors.initials: M
authors.lastname: Santiago
authors.forename: Michael
authors.initials: M
authors.lastname: Sitler
authors.forename: Guenther
authors.initials: G
authors.lastname: Boden
authors.forename: Carol
authors.initials: C
authors.lastname: Homko
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D005080:Exercise Test; D005260:Female; D015309:Glucose Clamp Technique; D006801:Humans; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance; D007537:Isometric Contraction / Q000502:physiology; D008297:Male; D009043:Motor Activity; D018482:Muscle, Skeletal / Q000502:physiology; D055070:Resistance Training; D011795:Surveys and Questionnaires; D014891:Weight Lifting; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D007328:Insulin