A mild, catalytic and efficient Nazarov cyclization mediated by phosphomolybdic acid.
A mild, selective and efficient Nazarov cyclization of divinyl ketones catalyzed by phosphomolybdic acid (PMA) is described. The process demonstrates a broad substrate scope with functional group tolerance under short reaction times. PMA supported on silica gel is more efficient than the bulk catalyst and is recycled up to three times without significant activity loss.
Murugan
Kaliyappan
K
Department of Chemistry, National Dong Hwa University, Shoufeng, Hualien 974, Taiwan, Republic of China.
Srimurugan
Sankareswaran
S
Chen
Chinpiao
C
D002070:Butadienes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D008982:Molybdenum / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry
D002070:Butadienes; D007659:Ketones; D010756:Phosphoric Acids; D012822:Silicon Dioxide; D008982:Molybdenum; C031763:1,3-butadiene; C003125:phosphomolybdic acid