title: Depression, anxiety and anger in subtypes of irritable bowel syndrome patients.
abstract: The present study aimed to elucidate the differences in depression, anxiety, anger, and quality of life in a sample of non-psychiatric IBS patients, starting from the hypothesis that IBS subtypes may have different symptomatic expressions of negative emotions with different outcomes on quality of life measures. Forty-two constipation-predominant IBS (C-IBS) subjects and 44 diarrhea-predominant IBS (D-IBS) subjects, after an examination by a gastroenterologist and a total colonoscopy, underwent a clinical interview and psychometric examination for the assessment of depression, anxiety, anger and quality of life. IBS subtypes showed different symptomatic profiles in depression, anxiety and anger, with C-IBS patients more psychologically distressed than D-IBS subjects. Affective and emotional symptoms should be considered as specific and integral to the syndrome, and recognizing the differences between IBS subtypes may have relevant implications for treatment options and clinical outcome.
authors.affiliation: Department of Neurosciences, Psychiatric Sciences and Anaesthesiology, University of Messina, Messina, Italy.
authors.forename: Maria Rosaria A
authors.initials: MR
authors.lastname: Muscatello
authors.forename: Antonio
authors.initials: A
authors.lastname: Bruno
authors.forename: Gianluca
authors.initials: G
authors.lastname: Pandolfo
authors.forename: Umberto
authors.initials: U
authors.lastname: Micò
authors.forename: Simona
authors.initials: S
authors.lastname: Stilo
authors.forename: Mariagrazia
authors.initials: M
authors.lastname: Scaffidi
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Consolo
authors.forename: Andrea
authors.initials: A
authors.lastname: Tortora
authors.forename: Socrate
authors.initials: S
authors.lastname: Pallio
authors.forename: Giuseppa
authors.initials: G
authors.lastname: Giacobbe
authors.forename: Luigi
authors.initials: L
authors.lastname: Familiari
authors.forename: Rocco
authors.initials: R
authors.lastname: Zoccali
mesh_terms: D000328:Adult; D000786:Anger; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000453:epidemiology* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires