title: [Results of fine-needle aspiration cytology (FNAC) in the diagnosis of indeterminate solid renal tumours].
abstract: OBJECTIVE
  To evaluate the accuracy of fine-needle aspiration cytology for the diagnosis of imaging indeterminate solid renal tumours.
  
  
  METHODS
  From February 2003 to February 2009, 60 cytoaspirations have been performed to 20 female and 40 male patients (average age: 62.0+/-14.2 years) with an indeterminate solid renal mass by imaging. The average tumour size was 3.4+/-2.8 cm. The cytoaspiration was performed through a 22 Gauge needle under CT (n=39) or US (n=21) guidance. Papanicolaou staining was used. All slides were examined by one experienced cytologist without any clinicoradiological information. The results were given as malignant, benign, suspect or non significant. A classification of subtypes of renal cancer might be added by the cytologist.
  
  
  RESULTS
  Twenty-one cytoaspirations (35%) were non significant while 39 (65%) showed cells of interest. Among these 39 cellular cytoaspirations, the specificity for malignancy or benignity was 89.7%. The proportion of non-significant samples was the same in tumors lesser than 2 cm (38.4%) as in tumors 2-4 cm (38.8%) (p=1.000, Fisher's exact test). Subtype identification was only reliable for clear cell carcinomas. No complication was observed.
  
  
  CONCLUSIONS
  The fine-needle aspiration cytology is an auxiliary technique for the diagnosis of indeterminate solid renal tumours. This simple and mini-invasive technique had a high specificity but a low sensitivity in our experience. Fine-needle aspiration is complementary to core biopsy which remains the gold standard of percutaneous sampling.
authors.affiliation: Service d'urologie-andrologie, CHU de Saint-Etienne, université Jean-Monnet, Saint-Etienne, France. grli2001@yahoo.fr
authors.forename: G
authors.initials: G
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Cuilleron
authors.forename: M
authors.initials: M
authors.lastname: Cottier
authors.forename: B
authors.initials: B
authors.lastname: Rambaud
authors.forename: J
authors.initials: J
authors.lastname: Tostain
authors.forename: M
authors.initials: M
authors.lastname: Gigante
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D055815:Young Adult