title: Treatment outcome of mineral trioxide aggregate: repair of root perforations.
abstract: BACKGROUND
  The use of biocompatible materials like mineral trioxide aggregate (MTA) may improve the prognosis of teeth with root perforations.
  
  
  METHODS
  The treatment outcome of root perforations repaired between 2000 and 2006 with MTA was investigated. Twenty-six patients received treatment with MTA in 26 teeth with root perforations. Treatment was performed by supervised undergraduate students (29%), general dentists (52%), or dentists who had focused on endodontics (19%). Perforation repair by all treatment providers was performed using a dental operating microscope. Calibrated examiners assessed clinical and radiographic outcome 12 to 65 months after treatment (median 33 months, 81% recall rate). Pre-, intra-, and postoperative information relating to potential prognostic factors was evaluated.
  
  
  RESULTS
  Of 21 teeth examined, 18 teeth (86%) were classified as healed. None of the analyzed potential prognostic factors had a significant effect on the outcome.
  
  
  CONCLUSIONS
  MTA appears to provide a biocompatible and long-term effective seal for root perforations in all parts of the root.
authors.affiliation: Department of Conservative Dentistry, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany. johannes.mente@med.uni-heidelberg.de
authors.forename: Johannes
authors.initials: J
authors.lastname: Mente
authors.forename: Nathalie
authors.initials: N
authors.lastname: Hage
authors.forename: Thorsten
authors.initials: T
authors.lastname: Pfefferle
authors.forename: Martin Jean
authors.initials: MJ
authors.lastname: Koch
authors.forename: Beate
authors.initials: B
authors.lastname: Geletneky
authors.forename: Jens
authors.initials: J
authors.lastname: Dreyhaupt
authors.forename: Nicolas
authors.initials: N
authors.lastname: Martin
authors.forename: Hans Joerg
authors.initials: HJ
authors.lastname: Staehle
mesh_terms: D000328:Adult; D017607:Aluminum Compounds / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000627:therapeutic use*; D003762:Dental Instruments / Q000009:adverse effects; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D017823:Furcation Defects / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D018915:Root Canal Preparation / Q000009:adverse effects / Q000295:instrumentation; D017640:Silicates / Q000627:therapeutic use*; D018709:Statistics, Nonparametric; D018677:Tooth Injuries / Q000209:etiology / Q000628:therapy*; D014092:Tooth Root / Q000293:injuries*; D016896:Treatment Outcome
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate