title: Intraoperative radiation exposure with the use of (18)F-FDG-guided thyroid cancer surgery.
abstract: Radio-guided surgery is an established means for surgeons to identify a target of interest for biopsy or excision. This technique is used for a variety of malignancies as well as minimally invasive parathyroid surgery. The primary radionuclide used for these procedures is technetium-99m (Tc-99m), but others have been used. Use of (18)fluorine-fluorodeoxyglucose ((18)F-FDG) in oncology has proliferated. This has created the opportunity to use (18)F-FDG as a potential radio tracer in the operating room. A pilot study of three patients with non-iodine avid thyroid cancers undergoing (18)F-FDG-guided revision thyroid cancer surgery is reported. Radiation exposure to operating room personnel was measured. Radiation exposure to the surgeon and staff members of an operating room is well below the limits of the National Regulatory Commission. Therefore, utilization of this radiopharmaceutical intraoperatively should not be limited in the future because of concern regarding exposure of operating room personnel to radiation.
authors.affiliation: Department of Orthopedic Surgery, University of South Florida, Tampa, FL, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Nalley
authors.forename: Kim
authors.initials: K
authors.lastname: Wiebeck
authors.forename: Twyla B
authors.initials: TB
authors.lastname: Bartel
authors.forename: Donald
authors.initials: D
authors.lastname: Bodenner
authors.forename: Brendan C
authors.initials: BC
authors.lastname: Stack
mesh_terms: D019788:Fluorodeoxyglucose F18; D006801:Humans; D007432:Intraoperative Period; D019060:Minimally Invasive Surgical Procedures; D016273:Occupational Exposure / Q000517:prevention & control*; D010865:Pilot Projects; D049268:Positron-Emission Tomography / Q000009:adverse effects; D011834:Radiation Monitoring; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18