[Bronchopulmonary manifestations of gastroesophageal reflux disease].
Gastroesophageal reflux disease (GERD) is a common disease in the western world. Usually it occurs with typical symptoms like heartburn and regurgitation, but almost every third GERD-patient presents with extraesophageal symptoms and diseases in which a causal relation with GERD is discussed. The extraesophageal symptoms possibly associated with GERD are chronic cough, bronchial asthma, sleep disturbances including obstructive sleep apnea, hoarseness, dental erosions, non-cardiac chest pain and idiopathic pulmonary fibrosis. This article gives an overview of the reflux-associated diseases of the airways as well as the proposed pathomechanisms and therapeutic options.
Malfertheiner
M V
MV
Fachbereich für Pneumologie, Otto-von-Guericke-Universität Magdeburg, Leipziger Strasse 44, 39120, Magdeburg, Deutschland.
Kandulski
A
A
Malfertheiner
P
P
Schreiber
J
J
D001249:Asthma / Q000209:etiology; D001982:Bronchial Diseases / Q000209:etiology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D004935:Esophageal Diseases / Q000175:diagnosis / Q000209:etiology; D050782:Esophageal pH Monitoring; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000209:etiology; D008171:Lung Diseases / Q000209:etiology*; D010348:Patient Care Team; D020181:Sleep Apnea, Obstructive / Q000209:etiology