Analysis of risk factors associated with recurrence of nasopharyngeal angiofibroma.
OBJECTIVE
Surgical outcomes and prognostic factors were analyzed to determine what factors increase the probability of juvenile nasopharyngeal angiofibroma (JNA) recurrence.


METHODS
Ninety-seven males with JNA were diagnosed and underwent surgery at Fudan University Affiliated Eye, Ear, Nose and Throat Hospital from 1997 to 2006. Clinical data were extracted from medical records and were used in the statistical analysis.


RESULTS
The total recurrence rate of JNA was 39.2% after the initial surgery. A patient whose tumour staging was higher was more likely to have a recurrence than a patient whose tumour staging was lower (p = .0031). The recurrence rates in two groups (age >or= 18 years group and < 18 years group) were 26.8% and 48.2%, respectively (p = .03). The recurrence rates with tumour size < 4 cm and >or= 4 cm were 21.7% and 54.9%, respectively (p = .0008).


CONCLUSIONS
The significant predictors of recurrence in our study were age at diagnosis, tumour size, and Radkowski classification.
Sun
Xi-Cai
XC
Department of Otolaryngology-Head and Neck Surgery, Fudan University Affiliated Eye, Ear, Nose and Throat Hospital, Shanghai, China.
Wang
De-Hui
DH
Yu
Hua-Peng
HP
Wang
Feng
F
Wang
Wei
W
Jiang
Jack J
JJ
D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004844:Epistaxis / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D015508:Nasal Obstruction / Q000453:epidemiology; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D009367:Neoplasm Staging; D012008:Recurrence; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D055815:Young Adult