title: Pruritus in cutaneous T-cell lymphomas: frequent, often severe and difficult to treat.
abstract: Pruritus has a well-known association with Hodgkin's disease and other nodal lymphomas; indeed it often reveals the disease. Pruritus is also an important symptom of cutaneous T-cell lymphomas. Lymphoma-associated itch is thus both frequent and severe, but its pathophysiology remains unclear. Few studies have evaluated the efficacy of therapeutic agents in the management of cutaneous T-cell lymphoma-related pruritus. The main objective of treatment remains disease control. Pruritus management is generally based on the physician's experience. Treatment is very difficult, especially in Sézary syndrome. We present here management strategies for cutaneous lymphoma-associated pruritus.
authors.affiliation: Service de Dermatologie, Université Paul Sabatier-Toulouse III et CHU Toulouse, Toulouse, France. meyer.n@chu-toulouse.fr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Meyer
authors.forename: Carle
authors.initials: C
authors.lastname: Paul
authors.forename: Laurent
authors.initials: L
authors.lastname: Misery
mesh_terms: D000982:Antipruritics / Q000627:therapeutic use*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000628:therapy; D010789:Phototherapy; D011537:Pruritus / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012720:Severity of Illness Index; D012751:Sezary Syndrome / Q000150:complications* / Q000628:therapy; D012878:Skin Neoplasms / Q000150:complications* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000982:Antipruritics