title: Fetotoxicity of warfarin anticoagulation.
abstract: BACKGROUND
  Fetal warfarin syndrome (warfarin embryopathy) is a consequence of maternal ingestion of warfarin during pregnancy. Warfarin fetotoxicity comprises wide range of manifestations including dysmorphology in neonate with characteristic classical features of nasal hypoplasia and stippling of epiphyses.
  
  
  METHODS
  Here we present a case of a neonate whose mother was on unsupervised warfarin prophylaxis throughout pregnancy. A brief review of literature with suitable options for anticoagulation during pregnancy is discussed.
  
  
  CONCLUSIONS
  The final consensus over LMWH and warfarin in the first trimester is yet to be finalised. The treatment of warfarin embryopathy is symptomatic. Long term sequels in survivors are still not known.
authors.affiliation: Department of Pediatrics, UCMS and GTB Hospital, Dilshad Garden, Delhi, India. drsmehndiratta@gmail.com
authors.forename: Sumit
authors.initials: S
authors.lastname: Mehndiratta
authors.forename: Amita
authors.initials: A
authors.lastname: Suneja
authors.forename: Bindiya
authors.initials: B
authors.lastname: Gupta
authors.forename: Shuchi
authors.initials: S
authors.lastname: Bhatt
mesh_terms: D000014:Abnormalities, Drug-Induced; D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D010009:Osteochondrodysplasias / Q000139:chemically induced*; D011247:Pregnancy; D014812:Vitamin K / Q000037:antagonists & inhibitors; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014812:Vitamin K; D014859:Warfarin