Metrorrhagia in a human immunodeficiency virus positive woman caused by cervical histoplasmosis.
In patients with AIDS, infection with Histoplasma capsulatum frequently results in disseminated disease. We discuss a 42-year old HIV-infected woman presenting with fever, weight loss, pulmonary infiltrates, diarrhea, and metrorrhagia. Biopsy of bone marrow and skin demonstrated H capsulatum. Necrotic lesions of the uterine cervix, initially thought to represent cervical carcinoma, proved to be because of disseminated histoplasmosis. Involvement of the female genital tract by histoplasmosis is exceedingly rare, with cervical disease not having been described previously.
Cantor
Amy G
AG
Department of Medicine, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma 73126-0901, USA. amycantor@gmail.com
John
Jijo
J
Brown
Brent
B
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis*; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008796:Metrorrhagia / Q000175:diagnosis* / Q000209:etiology; D002577:Uterine Cervical Diseases / Q000150:complications / Q000175:diagnosis*