title: [Viral etiology of acute respiratory infection in children from Wenzhou between 2007 and 2008].
abstract: OBJECTIVE
  To study the viral etiology of acute respiratory infection (ARI)in children from Wenzhou, Zhejiang between 2007 and 2008.
  
  
  METHODS
  The nasopharyngeal aspirate samples were obtained from 5 097 hospitalized children with ARI. Seven common respiratory viruses, including respiratory syncytial virus (RSV), influenza virus A and B, parainfluenza viruses 1, 2 and 3 and adenovirus, were detected using direct immunofluorescence.
  
  
  RESULTS
  Viral agents were identified in 2 209 cases (43.3%).Of the 2 209, RSV was the most frequent (78.1%), followed by parainfluenza 3 (12.4%), influenza virus A (3.0%), adenovirus (2.8%), parainfluenza 1 (1.7%), influenza B (0.5%) and parainfluenza 2 (0.3%). The infants at ages of <3 months and <6 months had higher detection rate of viruses (53.6% and 49.2%, respectively). A highest detection rate of viruses was found in winter.
  
  
  CONCLUSIONS
  RSV is the leading pathogen of ARI in children from Wenzhou, Zhejiang between 2007 and 2008. The children at age of less than 6 months are susceptible to respiratory viruses. The viral activity peaks in winter.
authors.affiliation: Department of Pulmonary, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang 325000, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Chang
authors.forename: Chun-Yun
authors.initials: CY
authors.lastname: Li
authors.forename: Hai-Jing
authors.initials: HJ
authors.lastname: Li
authors.forename: Yun-Chun
authors.initials: YC
authors.lastname: Luo
authors.forename: Xiao-Fang
authors.initials: XF
authors.lastname: Chen
authors.forename: Shao-Yan
authors.initials: SY
authors.lastname: Yang
mesh_terms: D000208:Acute Disease; D000260:Adenoviruses, Human / Q000302:isolation & purification; D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009305:Nasopharynx / Q000821:virology; D009975:Orthomyxoviridae / Q000302:isolation & purification; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000821:virology*; D012621:Seasons; D013997:Time Factors