[A prospective, randomized, open and comparative study to evaluate the safety and efficacy of blue light treatment versus a topical benzoyl peroxide 5% formulation in patients with acne grade II and III].
BACKGROUND
Many acne patients improve after exposure to sunlight and there are many reports about the efficacy of blue light phototherapy on acne lesions.


OBJECTIVE
The purpose of this study was to evaluate efficacy and safety of blue light treatment versus topical benzoyl peroxide 5% formulation in patients with acne grades II and III.


METHODS
Sixty volunteers with facial acne were included and evaluated in 5 visits: the first one for screening, another 3 held on days 7, 14 and 28 of treatment, and the last one after 14 days of the end of treatment. Thirty of them were irradiated with Blue Light (8 times, twice a week) and the other thirty were treated with topical Benzoyl Peroxide 5% formulation, auto-applied twice a day, every day. We assessed the severity of acne by counting the lesions and analyzing the photographs.


RESULTS
The improvement achieved by the blue light was the same as the one with benzoyl peroxide, regardless of the type of lesion (p 0.05). Otherwise, the side effects were less frequent in the group treated with blue light.


CONCLUSIONS
Blue light irradiation was as effective as benzoyl peroxide in acne treatment grades II and III but there were fewer side effects.
de Arruda
Lúcia H F
LH
Serviço de Dermatologia, Hospital Escola Celso Pierro, Faculdade de Medicina, Pontifícia Universidade Católica de Campinas, Campinas, SP, Brasil. dermato@hmcp.puc-campinas.edu.br
Kodani
Vanessa
V
Bastos Filho
Antonio
A
Mazzaro
Carla Bassanezi
CB
D000152:Acne Vulgaris / Q000628:therapy*; D000287:Administration, Topical; D000293:Adolescent; D001585:Benzoyl Peroxide / Q000008:administration & dosage* / Q000009:adverse effects; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D010789:Phototherapy; D011446:Prospective Studies; D012720:Severity of Illness Index
D003879:Dermatologic Agents; D001585:Benzoyl Peroxide