Evaluation of two portable meters for determination of blood triglyceride concentration in dogs.
OBJECTIVE
To evaluate agreement between 2 portable triglyceride meters and a veterinary laboratory for measurement of blood triglyceride concentrations in dogs and evaluate effects of Hct and blood volume analyzed.


METHODS
97 blood samples collected from 60 dogs.


METHODS
Triglyceride concentrations were measured in blood by use of 2 meters and compared with serum triglyceride concentrations determined by a veterinary laboratory. Within- and between-day precision, accuracy, and effects of blood volume and Hct were analyzed.


RESULTS
Accuracy of both meters varied with triglyceride concentration, although both accurately delineated dogs with triglyceride concentrations < 180 mg/dL versus > or = 180 mg/dL. One meter had results with excellent overall correlation with results of the standard laboratory method, with a concordance correlation coefficient of 0.94 and mean difference of 20.3 mg/dL. The other meter had a good overall concordance correlation coefficient of 0.86 with a higher absolute mean difference of -27.7 mg/dL. Results were only affected by blood volume; triglyceride concentrations determined via both meters were significantly lower when 7 microL of EDTA-anticoagulated blood was used, compared with larger volumes.


CONCLUSIONS
1 meter had greater accuracy in the range of 140 to 400 mg/dL and was therefore well suited to detect hypertriglyceridemia. The other meter was accurate with triglyceride values < 140 mg/dL and yielded results similar to those of the veterinary laboratory in the range of 140 to 400 mg/dL, therefore being suitable for determination of triglyceride concentrations in nonfed dogs and dogs with mildly high concentrations.
Kluger
Elissa K
EK
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia. ekluger@hotmail.com
Dhand
Navneet K
NK
Malik
Richard
R
Ilkin
William J
WJ
Snow
David H
DH
Govendir
Merran
M
D000818:Animals; D004285:Dogs / Q000097:blood*; D005260:Female; D006400:Hematocrit / Q000662:veterinary; D008297:Male; D019095:Point-of-Care Systems; D015203:Reproducibility of Results; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides