title: Swine flu: a Birmingham experience.
abstract: By the beginning of July 2009 the West Midlands had seen more cases of novel H1N1 influenza (swine flu) than any other region in the U.K. Over a three-week period almost 850 people presented to Heartlands Hospital with flu-like symptoms. Of those admitted 52 adults were subsequently confirmed as having H1N1 infection. Most were younger than 30 and not from traditional influenza risk groups. The main risk factor for severe disease was asthma, and to a lesser extent pregnancy and obesity. Seven patients were admitted to intensive care and five developed an acute lung injury requiring prolonged admission. Two patients required extra corporeal membrane oxygenation and one died. Despite increased workload normal clinical services were unaffected. The hospital was not closed to admissions nor was it paralysed by staff absence. With a predicted second wave expected at the end of 2009, efforts to maintain effective community assessment remain crucial.
authors.affiliation: Department of Infection and Tropical Medicine, Heartlands Hospital, Birmingham.
authors.forename: James
authors.initials: J
authors.lastname: Scriven
authors.forename: Ruth
authors.initials: R
authors.lastname: Mcewen
authors.forename: Sanjay
authors.initials: S
authors.lastname: Mistry
authors.forename: Chris
authors.initials: C
authors.lastname: Green
authors.forename: Husam
authors.initials: H
authors.lastname: Osman
authors.forename: Mark
authors.initials: M
authors.lastname: Bailey
authors.forename: Christopher
authors.initials: C
authors.lastname: Ellis
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications / Q000453:epidemiology; D004279:DNA, Viral / Q000032:analysis*; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods*; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics*; D007251:Influenza, Human / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D010343:Patient Admission / Q000706:statistics & numerical data*; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000821:virology; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D004279:DNA, Viral