title: High-dose-rate brachytherapy for patients with maxillary gingival carcinoma using a novel customized intraoral mold technique.
abstract: OBJECTIVE
  The purpose of this study was to introduce a novel customized intraoral mold treatment for maxillary gingival carcinoma (UGC).
  
  
  METHODS
  Two patients with UGC were treated as salvage therapy using this technique. The mold was designed to keep normal soft tissues adjacent to the tumor away from the radioactive source as much as possible, and it was shielded by lead. The radiation dose on the buccal mucosa and tongue was measured at the inner and outer surfaces of the intraoral mold before starting high-dose-rate brachytherapy by the remote afterloading system, and was reduced to almost one tenth.
  
  
  RESULTS
  The patient had no recurrence and no severe adverse effects on the normal soft tissue adjacent to the tumor until the end of the follow-up period.
  
  
  CONCLUSIONS
  High-dose-rate brachytherapy using the novel customized intraoral mold might be a treatment option of not only salvage therapy, but definitive therapy of UGC.
authors.affiliation: Department of Oral and Maxillofacial Radiology, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan. kudoh@dent.tokushima-u.ac.jp
authors.forename: Takaharu
authors.initials: T
authors.lastname: Kudoh
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ikushima
authors.forename: Keiko
authors.initials: K
authors.lastname: Kudoh
authors.forename: Reiko
authors.initials: R
authors.lastname: Tokuyama
authors.forename: Kyohsuke
authors.initials: K
authors.lastname: Osaki
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Furutani
authors.forename: Takashi
authors.initials: T
authors.lastname: Kawanaka
authors.forename: Akiko
authors.initials: A
authors.lastname: Kubo
authors.forename: Hiromu
authors.initials: H
authors.lastname: Nishitani
authors.forename: Eiichi
authors.initials: E
authors.lastname: Honda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000295:instrumentation*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D019583:Dose Fractionation, Radiation; D005260:Female; D005887:Gingival Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008437:Maxilla; D011835:Radiation Protection / Q000295:instrumentation; D016879:Salvage Therapy / Q000295:instrumentation*