[Hepatitis E infection in dialysis and after transplantation].
Hepatitis E virus (HEV) causes epidemics of acute hepatitis in developing countries, and also appears to be an emerging agent in industrialized countries. HEV infection is transmitted via the fecal-oral route, and may be a zoonosis in industrialized countries. HEV infection was thought to be responsible for acute hepatitis that does not become chronic. However, it has been recently reported that HEV infection can evolve to chronic hepatitis and to cirrhosis, at least in solid-organ transplant patients. The reduction of immunosuppressive drugs could be considered as a first-line therapeutic option.
Kamar
Nassim
N
Service de néphrologie, dialyse et transplantation multi-organes, CHU Rangueil, TSA 50032, 31059 Toulouse cedex 9, France. kamar.n@chu-toulouse.fr
Abravanel
Florence
F
Mansuy
Jean-Michel
JM
Peron
Jean-Marie
JM
Izopet
Jacques
J
Rostaing
Lionel
L
D019049:Developed Countries; D003906:Developing Countries; D005602:France / Q000453:epidemiology; D016751:Hepatitis E / Q000175:diagnosis* / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D016752:Hepatitis E virus / Q000302:isolation & purification; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015994:Incidence; D016030:Kidney Transplantation; D008103:Liver Cirrhosis / Q000821:virology; D015995:Prevalence; D006435:Renal Dialysis
D007166:Immunosuppressive Agents