[A study of intratumor microvessel density and lymph node micrometastases of pN0 supraglottic laryngeal squamous cell carcinoma].
OBJECTIVE
To investigate the correlation between intratumor microvessel density(IMVD) and lymph node micrometastases.


METHODS
IMVD and lymph node micrometastases were stained with CD105 and CK19 antibody by immunohistochemical method of SABC respectively.


RESULTS
IMVD marked with CD105 antibody correlated with T stage and lymph node micrometastases (P < 0.01).


CONCLUSIONS
The result show that IMVD marked with CD105 antibody highly correlated with lymph node micrometastases. It could be a index to evaluate the prognosis of patients with pN0 supraglottic laryngeal squamous cell carcinoma.
Li
Binghua
B
Department of Otolaryngology, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China. jackbhlee@yahoo.com.cn
Xu
Yaping
Y
Su
Lizhong
L
Chen
Mingyuan
M
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000098:blood supply* / Q000473:pathology*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000098:blood supply* / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D055806:Microvessels; D008875:Middle Aged; D009367:Neoplasm Staging