[Viral etiology of acute respiratory infection in children from Wenzhou between 2007 and 2008].
OBJECTIVE
To study the viral etiology of acute respiratory infection (ARI)in children from Wenzhou, Zhejiang between 2007 and 2008.


METHODS
The nasopharyngeal aspirate samples were obtained from 5 097 hospitalized children with ARI. Seven common respiratory viruses, including respiratory syncytial virus (RSV), influenza virus A and B, parainfluenza viruses 1, 2 and 3 and adenovirus, were detected using direct immunofluorescence.


RESULTS
Viral agents were identified in 2 209 cases (43.3%).Of the 2 209, RSV was the most frequent (78.1%), followed by parainfluenza 3 (12.4%), influenza virus A (3.0%), adenovirus (2.8%), parainfluenza 1 (1.7%), influenza B (0.5%) and parainfluenza 2 (0.3%). The infants at ages of <3 months and <6 months had higher detection rate of viruses (53.6% and 49.2%, respectively). A highest detection rate of viruses was found in winter.


CONCLUSIONS
RSV is the leading pathogen of ARI in children from Wenzhou, Zhejiang between 2007 and 2008. The children at age of less than 6 months are susceptible to respiratory viruses. The viral activity peaks in winter.
Chang
Jie
J
Department of Pulmonary, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang 325000, China.
Li
Chun-Yun
CY
Li
Hai-Jing
HJ
Luo
Yun-Chun
YC
Chen
Xiao-Fang
XF
Yang
Shao-Yan
SY
D000208:Acute Disease; D000260:Adenoviruses, Human / Q000302:isolation & purification; D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009305:Nasopharynx / Q000821:virology; D009975:Orthomyxoviridae / Q000302:isolation & purification; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000821:virology*; D012621:Seasons; D013997:Time Factors