Prediction of good functional recovery after stroke based on combined motor and somatosensory evoked potential findings.
OBJECTIVE
To delineate whether functional recovery after stroke, determined by the modified Rankin Scale during the neurologically stable chronic stage, is associated with the presence or absence of motor evoked potential or somatosensory evoked potential measured during the sub-acute stage at the commencement of rehabilitation.


METHODS
Retrospective medical records review.


METHODS
Consecutive 105 first-ever unilateral patients after stroke.


METHODS
Patients underwent motor evoked potential and somatosensory evoked potential studies at the commencement of rehabilitation (i.e. approximately 1 month post-onset), and functional recovery was measured using the modified Rankin Scale at 3 months post-onset. The independent abilities of motor evoked potentials and somatosensory evoked potentials for predicting good functional recovery (modified Rankin Scale < or = 2) were determined by multivariable logistic regression analysis adjusted for age, laterality of lesion, and National Institute of Health Stroke Scale scores at onset of rehabilitation.


RESULTS
The adjusted logistic regression model revealed that patients with negative motor evoked potential or somatosensory evoked potential responses in the lower limb were less likely to achieve good functional recovery (odds ratio=0.057-0.099, p<0.05) relative to positive motor evoked potential and somatosensory evoked potential responses in the lower limb.


CONCLUSIONS
Evoked potential studies measured at the commencement of rehabilitation could be used in a complementary manner to predict functional recovery after stroke.
Lee
Sang Yoon
SY
Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, South Korea.
Lim
Jong Youb
JY
Kang
Eun Kyoung
EK
Han
Moon-Ku
MK
Bae
Hee-Joon
HJ
Paik
Nam-Jong
NJ
D000368:Aged; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D011379:Prognosis; D020127:Recovery of Function / Q000502:physiology; D012189:Retrospective Studies; D020521:Stroke / Q000503:physiopathology; D000071939:Stroke Rehabilitation