title: [Laparoscopic treatment of perforated duodenal ulcer: 84 cases in Tunisia].
abstract: BACKGROUND
  The purpose of this study was to evaluate the feasibility, efficacy and safety of the laporascopic treatment of perforated duodenal ulcer.
  
  
  METHODS
  This retrospective study included patients who underwent laparoscopic treatment of perforated duodenal ulcer during the seven-year period from 2001 to 2007. The procedure included direct suture of the perforated ulcer followed by peritoneal lavage. All patients received medical treatment including Helicobacter pylori eradication and proton pump inhibitor therapy.
  
  
  RESULTS
  A total of 84 patients underwent laparoscopic surgery for perforated duodenal ulcer during the study period. There were 81 men and 3 women with a mean age of 28 years. Laparoscopic examination confirmed diagnosis of perforated duodenal ulcer in all cases. Direct suture of the ulcer was successful in 72 cases. In the remaining 12 cases conversion to open surgery was necessary due to difficulty in achieving peritoneal lavage in 6 cases, ulcer size and edge friability in 5, and septic shock in one. The mean duration of the procedure was 95 minutes (range, 60 to 180 minutes). The mean postoperative complication rate was 15.4%. Complications included peritonintis in one case and digestive fistula in one. There were no postoperative deaths. All patients were re-examined after 25 months. Two patients presented recurrences after the laparoscopic treatment and required tri-therapy.
  
  
  CONCLUSIONS
  Laparoscopic suture of perforated duodenal ulcer is safe and effective. It avoids the need for laparotomy that is associated with a risk for septic and parietal complications. Since medical treatment is effective for ulcerous disease, there are currently no indications for radical treatment.
authors.affiliation: Service de chirurgie géndrale, Hôpital Habib Bourguiba, Sfax, Tunisie. abid_med_chu@yahoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Abid
authors.forename: M
authors.initials: M
authors.lastname: Ben Amar
authors.forename: A
authors.initials: A
authors.lastname: Guirat Moheddine
authors.forename: H
authors.initials: H
authors.lastname: Cheikhrouhou
authors.forename: A
authors.initials: A
authors.lastname: Amouri
authors.forename: M
authors.initials: M
authors.lastname: Khlif
authors.forename: R
authors.initials: R
authors.lastname: Mzali
authors.forename: F
authors.initials: F
authors.lastname: Frikha
authors.forename: M I
authors.initials: MI
authors.lastname: Beyrouti
mesh_terms: D000293:Adolescent; D000328:Adult; D004381:Duodenal Ulcer / Q000150:complications / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000601:surgery*; D010533:Peritoneal Lavage; D011183:Postoperative Complications; D012189:Retrospective Studies; D014416:Tunisia