Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions.
A copper(i) catalyzed amination reaction utilizing aqueous ammonia and operating under mild conditions is presented. This method was employed for the efficient synthesis of various aminopyridine derivatives bearing electron withdrawing and electron donating groups.
Elmkaddem
Mohammed K
MK
UMR 6226-CNRS-Université de Rennes 1, Sciences Chimiques de Rennes, Catalyse et Organométalliques, Campus de Beaulieu, avenue du général Leclerc, 35042 Rennes cedex, France.
Fischmeister
Cédric
C
Thomas
Christophe M
CM
Renaud
Jean-Luc
JL
D000586:Amination; D000631:Aminopyridines / Q000138:chemical synthesis* / Q000737:chemistry; D000641:Ammonia / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*
D000631:Aminopyridines; D000641:Ammonia; D003300:Copper