Early virologic response to pegylated interferon in chronic hepatitis B infection.
BACKGROUND
Early virologic response to pegylated interferon in the treatment of chronic hepatitis B infection is not frequently reported.


METHODS
The case notes of the patients was retrieved and relevant data extracted, literature review was done using Medline.


RESULTS
A report of a case of early virologic response in a 62 year old man with chronic hepatitis B infection, receiving pegylated interferon is presented with a review of the relevant literature. He had HBV DNA level assessed by PCR and histology of liver biopsy specimen.


CONCLUSIONS
Clinicians should be on the lookout for early virologic response to pegylated interferon and the eventual outcome of such early response.
Ladep
N G
NG
Department of Medicine, University of Jos/JUTH.
Ugiagbe
R A
RA
Okonkwo
U
U
Okeke
E N
EN
Malu
A O
AO
D000998:Antiviral Agents / Q000627:therapeutic use*; D004279:DNA, Viral / Q000276:immunology; D006515:Hepatitis B virus / Q000187:drug effects* / Q000276:immunology; D019694:Hepatitis B, Chronic / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D016133:Polymerase Chain Reaction; D011994:Recombinant Proteins; D016896:Treatment Outcome
D000998:Antiviral Agents; D004279:DNA, Viral; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; C100416:peginterferon alfa-2a