Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome complicated by seven pulmonary emboli in a 15-year old patient.
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome represents a spectrum of various dermatologic and musculoskeletal conditions. Thromboses have infrequently been reported in SAPHO syndrome, most often in the subclavian vein. There have been no reported cases of pulmonary emboli associated with SAPHO. We report a case of a young patient with SAPHO syndrome who later presented with extensive iliofemoral deep vein thromboses and seven pulmonary emboli.
Coloe
Jacquelyn
J
Ohio State University College of Medicine, Columbus, Ohio.
Diamantis
Stephanie
S
Henderson
Frederick
F
Morrell
Dean S
DS
D020083:Acquired Hyperostosis Syndrome / Q000150:complications* / Q000188:drug therapy; D000293:Adolescent; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D015474:Isotretinoin / Q000627:therapeutic use; D008297:Male; D011655:Pulmonary Embolism / Q000209:etiology*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use
D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D015474:Isotretinoin; D000068800:Etanercept