title: Asymmetrical cerebral perfusion demonstrated by noninvasive arterial spin-labeling perfusion imaging in a patient with corticobasal degeneration.
abstract: This is to report arterial spin-labeling (ASL) regional cerebral blood flow (rCBF) mapping findings in a case of corticobasal degeneration (CBD). A 68-year-old man gradually developed limb-kinetic apraxia, myoclonus, and rigidity in the left hand and was diagnosed as having CBD. Magnetic resonance imaging and single photon emission computed tomography revealed atrophy and decreased blood flow, respectively, in the right hemisphere, findings that were compatible with CBD. In addition, ASL rCBF mapping demonstrated asymmetrical hypoperfusion areas in locations typical for CBD, proving its potential usefulness for routine clinical differential diagnosis.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.
authors.forename: Tuvshinjargal
authors.initials: T
authors.lastname: Dashjamts
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshiura
authors.forename: Akio
authors.initials: A
authors.lastname: Hiwatashi
authors.forename: Koji
authors.initials: K
authors.lastname: Yamashita
authors.forename: Koichiro
authors.initials: K
authors.lastname: Abe
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Ohyagi
authors.forename: Junichi
authors.initials: J
authors.lastname: Kira
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D000368:Aged; D020240:Apraxia, Ideomotor / Q000209:etiology; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D002560:Cerebrovascular Circulation; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009207:Myoclonus / Q000209:etiology; D009410:Nerve Degeneration / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D010300:Parkinson Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D013113:Spin Labels; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D013113:Spin Labels