title: Formation of idiopathic macular hole-reappraisal.
abstract: OBJECTIVE
  The study is intended to examine the development of macular hole in idiopathic conditions.
  
  
  METHODS
  A 2-year case file of optical coherence tomography (OCT) with the initial diagnosis of idiopathic impending hole (IH) or lamellar hole (LH) was reviewed. All cases of IH or LH were sequentially examined for more than 9 months. All cases with IH had vitreo-foveal adhesion, and were separated into type A (foveal detachment +/- inner retinal cysts) and type B (inner retinal cysts only).
  
  
  RESULTS
  Eight cases had type A IH, 15 cases had type B IH, and 27 cases had LH. Seven cases of type A IH developed full-thickness macular hole (FTMH) at an average of 5.1 +/- 2.2 months, and the one other case was operated. Five cases of type B IH were operated. For the other ten cases, at an average of 11.4 +/- 3.5 months, none had developed foveal detachment or FTMH, but five had developed LH. Three cases with initial LH subsequently developed FTMH.
  
  
  CONCLUSIONS
  In idiopathic cases, vitreo-foveal traction with foveal detachment may lead to FHMH, while inner cysts only without foveal detachment seem tend to evolve into LH instead of FHMH. Furthermore, LH may develop into FTMH.
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, No. 7, Chung Shan South Road, Taipei, 100, Taiwan.
authors.forename: Po-Ting
authors.initials: PT
authors.lastname: Yeh
authors.forename: Ta-Ching
authors.initials: TC
authors.lastname: Chen
authors.forename: Chang-Hao
authors.initials: CH
authors.lastname: Yang
authors.forename: Tzyy-Chang
authors.initials: TC
authors.lastname: Ho
authors.forename: Muh-Shy
authors.initials: MS
authors.lastname: Chen
authors.forename: Jen-Shang
authors.initials: JS
authors.lastname: Huang
authors.forename: Chung-May
authors.initials: CM
authors.lastname: Yang
mesh_terms: D000268:Adhesiveness; D005584:Fovea Centralis / Q000378:metabolism; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008875:Middle Aged; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014822:Vitreous Body / Q000378:metabolism