title: Four new 2-arylbenzofuran derivatives from leaves of Morus alba L.
abstract: Four new 2-arylbenzofuran derivatives, moracins V-Y (1-4), together with two known compounds, moracin N (5) and moracin P (6), were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis. Moracins X (3) and Y (4) represent unusual substituted group compared with 2-arylbenzofuran derivatives, which were isolated from the genus Morus. Compounds 2-5 were evaluated for cytotoxicity against several human cancer cell lines.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.forename: Ting
authors.initials: T
authors.lastname: Gong
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.forename: Ruo-Yun
authors.initials: RY
authors.lastname: Chen
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D001572:Benzofurans / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001572:Benzofurans