Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings.
We present a previously healthy 6-month-old boy who was admitted to our hospital with lethargy, hypotonia and focal clonic seizures 6 days following diptheria, tetanus toxoid and whole-cell pertussis vaccination. A diagnosis of acute necrotising encephalopathy was made with the aid of MRI, including diffusion-weighted imaging and proton MR spectroscopy.
Aydin
Hale
H
Department of Radiology, Baskent University Hospital, Ziya Gokalp, Cad 10, sok No: 45 Bahcelievler, Ankara 06610, Turkey. halemaydin@gmail.com
Ozgul
Esra
E
Agildere
Ahmet Muhtesem
AM
D001921:Brain / Q000187:drug effects / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004165:Diphtheria / Q000150:complications*; D006801:Humans; D007223:Infant; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000139:chemically induced* / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D010567:Pertussis Vaccine / Q000009:adverse effects*; D013744:Tetanus Toxin; D013745:Tetanus Toxoid / Q000009:adverse effects*
D010567:Pertussis Vaccine; D013744:Tetanus Toxin; D013745:Tetanus Toxoid