title: Medical management update: Peutz Jeghers syndrome.
abstract: Peutz Jeghers syndrome (PJS) is an autosomal dominant disease characterized by hamartomatous polyposis and distinct mucocutaneous pigmentation. PJS is associated with an increased risk for several cancers and other complications such as small intestine intussusception, short bowel syndrome, and anemia. Medical management mainly consists of treatment of the polyps and surveillance. This medical management update will review clinical concepts, therapeutic advances, and emphasize features of PJS important to the oral health care provider.
authors.affiliation: Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.
authors.forename: Paola
authors.initials: P
authors.lastname: Higham
authors.forename: Faizan
authors.initials: F
authors.lastname: Alawi
authors.forename: Eric T
authors.initials: ET
authors.lastname: Stoopler
mesh_terms: D017742:Dental Care for Chronically Ill; D003937:Diagnosis, Differential; D006801:Humans; D008548:Melanosis / Q000209:etiology*; D009059:Mouth Diseases / Q000209:etiology*; D010580:Peutz-Jeghers Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy