Immunology: TL1A in the inflammatory network in autoimmune diseases.
Several lines of evidence both from experimental models and from clinical studies reveal that TNF-like ligand 1A (TL1A) and its interaction with death receptor 3 (DR3) is critically involved in the pathogenesis of rheumatoid arthritis and other autoimmune diseases.
Bayry
Jagadeesh
J
INSERM Unité 872, Equipe 16, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médicine, Paris, France. jagadeesh.bayry@crc.jussieu.fr
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D053219:Receptors, Tumor Necrosis Factor, Member 25 / Q000378:metabolism*; D053380:Tumor Necrosis Factor Ligand Superfamily Member 15 / Q000378:metabolism*
D053219:Receptors, Tumor Necrosis Factor, Member 25; D053380:Tumor Necrosis Factor Ligand Superfamily Member 15