[Analysis of a severe septic transfusion reaction with standard platelet concentrate].
We recently observed a near fatal case of transfusion-transmitted infection with standard platelet concentrate. Streptococcus dysgalactiae subspecies equisimilis was isolated both from donor, residual component container and cultures of the patient's blood. This should question the usefulness of systematic bacterial detection in platelet concentrates, however a lethal accident has occurred recently which escaped bacterial detection. This observation calls for implementation of pathogen inactivation procedures for platelets concentrates.
Courbil
R
R
EFS Auvergne-Loire, boulevard Pasteur, Saint-Etienne, France. remi.courbil@efs.sante.fr
Romaszko
J-P
JP
Odent-Malaure
H
H
Fabrigli
P
P
Chavarin
P
P
Tournilhac
O
O
Bay
J-O
JO
Fressy
P
P
Ergani
A
A
Bouvet
A
A
Bonnet
R
R
Garraud
O
O
D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology / Q000635:transmission*; D015373:Bacterial Typing Techniques; D001782:Blood Donors; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008403:Mass Screening; D008875:Middle Aged; D010614:Pharynx / Q000382:microbiology; D017713:Platelet Transfusion / Q000009:adverse effects* / Q000295:instrumentation; D012772:Shock, Septic / Q000209:etiology* / Q000382:microbiology; D013045:Species Specificity; D013290:Streptococcal Infections / Q000175:diagnosis / Q000635:transmission*; D013291:Streptococcus / Q000302:isolation & purification*; D013921:Thrombocytopenia / Q000209:etiology / Q000628:therapy