Dietary fructooligosaccharides and potential benefits on health.
Fructooligosaccharides (FOS) are oligosaccharides that occur naturally in plants such as onion, chicory, garlic, asparagus, banana, artichoke, among many others. They are composed of linear chains of fructose units, linked by beta (2-1) bonds. The number of fructose units ranges from 2 to 60 and often terminate in a glucose unit. Dietary FOS are not hydrolyzed by small intestinal glycosidases and reach the cecum structurally unchanged. There, they are metabolized by the intestinal microflora to form short-chain carboxylic acids, L -lactate, CO(2), hydrogen and other metabolites. FOS have a number of interesting properties, including a low sweetness intensity; they are also calorie free, non-cariogenic and are considered as soluble dietary fibre. Furthermore, FOS have important beneficial physiological effects such as low carcinogenicity, a prebiotic effect, improved mineral absorption and decreased levels of serum cholesterol, triacylglycerols and phospholipids. Currently FOS are increasingly included in food products and infant formulas due to their prebiotic effect stimulate the growth of nonpathogenic intestinal microflora. Their consumption increases fecal bolus and the frequency of depositions, while a dose of 4-15 g/day given to healthy subjects will reduce constipation, considered one of the growing problems of modern society, and newborns during the first months of life.
Sabater-Molina
M
M
Department of Physiology, University of Murcia, Spain. mariasm@um.es
Larqué
E
E
Torrella
F
F
Zamora
S
S
D001786:Blood Glucose / Q000187:drug effects; D002240:Carbohydrate Sequence; D003110:Colonic Neoplasms / Q000517:prevention & control; D003248:Constipation / Q000188:drug therapy; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D005232:Fatty Acids, Volatile / Q000378:metabolism; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007223:Infant; D041943:Infant Formula / Q000737:chemistry; D007231:Infant, Newborn; D007328:Insulin / Q000097:blood; D007408:Intestinal Absorption / Q000187:drug effects; D050356:Lipid Metabolism / Q000187:drug effects; D008895:Milk, Human; D008903:Minerals / Q000378:metabolism; D009844:Oligosaccharides / Q000494:pharmacology* / Q000627:therapeutic use*; D056692:Prebiotics
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D005232:Fatty Acids, Volatile; D007328:Insulin; D008903:Minerals; D009844:Oligosaccharides; D056692:Prebiotics; C116580:fructooligosaccharide