[Non-pharmacological influencing factors of motor complications in Parkinson's disease: a systematic review].
OBJECTIVE
To make a systematic review of risk factors associated with motor complications in Parkinson's disease (PD).


METHODS
Medline, EMbase and Cochrane Database were used to search for prospective and retrospective studies on the factors associated with dyskinesia and motor fluctuations. Methodological quality was checked by two independent reviewers.


RESULTS
Earlier age at onset, female gender and a long disease duration might be the risk factors of motor complications.


CONCLUSIONS
More high-quality clinical trials are required to evaluate the factors associated with motor complications.
Liu
Zhen-Guo
ZG
Department of Neurology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghi 200092, China. zhenguoliu2004@yahoo.com.cn
Zhou
Ming-Zhu
MZ
Chen
Wei
W
D015984:Causality; D020820:Dyskinesias / Q000453:epidemiology*; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy; D012307:Risk Factors