title: Giant cranionasal schwannoma.
abstract: Giant schwannomas concomitantly involving the intracranial and nasal cavities are rare. We report a 22-year-old male patient with a giant schwannoma involving the frontal skull base and extending into the nasal cavity. The patient had a 2-year history of nasal obstruction that was originally misdiagnosed as nasal polyps. A CT scan and an MRI revealed a large cranionasal tumor. Surgery was performed using a coronal incision with a bilateral frontal skull base extradural approach. The tumor originated from the anterior skull base and the dura and nasal mucosa were intact. Histopathology was consistent with a schwannoma. Schwannoma should be listed as part of the differential diagnosis of a cranionasal tumor and the surgical approach should be carefully selected to achieve total resection.
authors.affiliation: Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guoxuexiang Street, Chengdu, Sichuan, 610041, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Zheng
authors.forename: Shu
authors.initials: S
authors.lastname: Jiang
authors.forename: Jian-guo
authors.initials: JG
authors.lastname: Xu
authors.forename: Bo-yong
authors.initials: BY
authors.lastname: Mao
mesh_terms: D003951:Diagnostic Errors; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D009298:Nasal Polyps / Q000473:pathology; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery; D019292:Skull Base Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult