title: Computerized analysis of fetal heart rate in pregnancies complicated by gestational diabetes mellitus, gestational hypertension, intrauterine growth restriction and premature rupture of membranes.
abstract: OBJECTIVE
  We aimed to compare individual fetal heart rate (FHR) indices, as determined by computer analysis of the tracing, in pregnancies complicated by gestational diabetes mellitus (GDM), gestational hypertension (PIH), intrauterine growth restriction (IUGR) and premature rupture of membranes (pPROM).
  
  
  METHODS
  The study population consisted of 100 pregnant women affected by GDM on diet therapy, 100 pregnant women affected by GDM on insulin therapy, 100 pregnant women affected by PIH, 100 pregnant women affected by IUGR, 100 with premature rupture of membranes far from the term (pPROM) and 100 normal pregnancies matched for age, parity and gestation as controls. The 30-min FHR tracing was analyzed by computer.
  
  
  RESULTS
  Baseline FHR, the duration of episodes of low variation and short-term variation was significantly higher in pregnancies complicated by gestational diseases than in controls; only in PIH, IUGR and pPROM were a significant reduction of the numbers of fetal movements.
  
  
  CONCLUSIONS
  Our study demonstrates that pregnancies complicated by gestational diseases do an impact on FHR. The alteration is slight but evident; it reflects fetal well-being. Computerized FHR tracing analysis may improve the clinical care and the timing of delivery.
authors.affiliation: Institute for Maternal and Child Sciences, Marche Polytechnic University, Ancona, Italy. g.buscicchio@virgilio.it
authors.forename: Giorgia
authors.initials: G
authors.lastname: Buscicchio
authors.forename: Lucia
authors.initials: L
authors.lastname: Gentilucci
authors.forename: Andrea L
authors.initials: AL
authors.lastname: Tranquilli
mesh_terms: D000328:Adult; D015148:Cardiotocography / Q000379:methods; D003201:Computers; D016640:Diabetes, Gestational / Q000178:diet therapy / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology*; D005322:Premature Rupture of Fetal Membranes / Q000503:physiopathology*; D005865:Gestational Age; D006340:Heart Rate, Fetal; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D011247:Pregnancy