title: [Relationship of fatty liver with HBV infection, hyperlipidemia and abnormal alanine aminotransferase].
abstract: OBJECTIVE
  To investigate the prevalence of fatty liver in Guangzhou and its relation to hepatitis B virus (HBV) infection, hyperlipidemia and abnormal alanine aminotransferase (ALT).
  
  
  METHODS
  A retrospective analysis was made on clinical data of 4365 participants who received health check-up in our hospital.
  
  
  RESULTS
  The prevalence of fatty liver was 18.2%, 19.2% in males and 17.1% in females, respectively. There was no significant difference between males and females (P = 0.07). Among 793 subjects with fatty liver, 440 were males and 353 were females. The prevalence of fatty liver was 16.7% in HBV infection group and 18.3% in the group without HBV infection, no significant difference was seen between these two groups (P = 0.45). The prevalence of fatty liver was 42.1% in hyperlipidemia group, and 11.6% in the group with normal serum triglyceride (TG) and total cholesterol (TC), respectively, there was a significant difference between these two groups (P < 0.05). The abnormal ALT was seen in 32.5% of the fattty liver group, which was significantly higher than that (8.6%) in the group without fatty liver (P < 0.05).
  
  
  CONCLUSIONS
  The prevalence of fatty liver was not significantly different between males and females in Guangzhou. Fatty liver was not related with HBV infection but closely related with age and hyperlipidemia. Fatty liver was a common cause of abnormal ALT.
authors.affiliation: Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. xqh0303@yahoo.com.cn
authors.forename: Qi-huan
authors.initials: QH
authors.lastname: Xu
authors.forename: Yu-sheng
authors.initials: YS
authors.lastname: Jie
authors.forename: Xin
authors.initials: X
authors.lastname: Shu
authors.forename: Lu-biao
authors.initials: LB
authors.lastname: Chen
authors.forename: Hong
authors.initials: H
authors.lastname: Cao
authors.forename: Gang
authors.initials: G
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000410:Alanine Transaminase / Q000097:blood*; D002681:China / Q000453:epidemiology; D005234:Fatty Liver / Q000097:blood* / Q000201:enzymology / Q000453:epidemiology / Q000821:virology*; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000821:virology*; D006515:Hepatitis B virus / Q000302:isolation & purification / Q000502:physiology*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000410:Alanine Transaminase