title: [The level of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and nonalcoholic fatty liver].
abstract: OBJECTIVE
  To study the roles of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver.
  
  
  METHODS
  The level of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver was detected by ELISA after culturing for 72 hours in vitro, as well as patients with chronic hepatitis C and the normal control.
  
  
  RESULTS
  (1) Compared with the normal control, the level of TNF-alpha in group with chronic hepatitis C and in group with chronic hepatitis C and Nonalcoholic fatty liver notably increased. (2) Compared with the group with chronic hepatitis C, the level of TNF-alpha in group with chronic hepatitis C and Nonalcoholic fatty liver also notably increased.
  
  
  CONCLUSIONS
  It suggested TNF-alpha takes important roles in the infection course of chronic hepatitis C with Nonalcoholic fatty liver.
authors.affiliation: Department of Immunology, Institute of Infectious Diseases, the No. 302 Hospital of the People's Liberation Army, Beijing 100039, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Dong
authors.forename: Hong-fei
authors.initials: HF
authors.lastname: Zhang
authors.forename: Shi-shu
authors.initials: SS
authors.lastname: Zhu
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Cheng
mesh_terms: D000293:Adolescent; D000328:Adult; D002478:Cells, Cultured; D002648:Child; D005234:Fatty Liver / Q000378:metabolism*; D005260:Female; D019698:Hepatitis C, Chronic / Q000378:metabolism*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*; D055815:Young Adult
chemical_list: D014409:Tumor Necrosis Factor-alpha