title: Female urethral malignant melanoma with vesical invasion: a case report.
abstract: We report a 75-year-old female with a primary urethral malignant melanoma. Amass protruding from inside the urethra was detected on physical examination. Abdominopelvic magnetic resonance imaging revealed a mass extending from the urethra with dimensions of 4x2 cm, and periurethral heterogenous fatty planes consistent with infiltration. The histopathologic examination was consistent with HMB45(+) malignant melanoma. We performed cystourethrectomy and bilateral inguinal and pelvic lymphadenectomy in one session. The pathology report revealed primary malignant melanoma of the urethra invading the inferior bladder wall. The patient received no adjuvant therapy because of cardiopulmonary morbidities and the presence of multiple pulmonary metastases. The patient eventually died 13 months after surgery.
authors.affiliation: Department of Urology, Vakif Gureba Training and Research Hospital, Istanbul, Turkey. alpaslanakbas@gmail.com
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Akbas
authors.forename: Tolga
authors.initials: T
authors.lastname: Akman
authors.forename: Mehmet Remzi
authors.initials: MR
authors.lastname: Erdem
authors.forename: Baran
authors.initials: B
authors.lastname: Antar
authors.forename: Isin
authors.initials: I
authors.lastname: Kilicarslan
authors.forename: Sinasi Yavuz
authors.initials: SY
authors.lastname: Onol
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D014523:Urethral Neoplasms / Q000473:pathology* / Q000601:surgery; D001743:Urinary Bladder / Q000473:pathology