Advances in sonographic detection of ovarian cancer: depiction of tumor neovascularity with microbubbles.
OBJECTIVE
The purpose of this article is to discuss and illustrate the use of contrast-enhanced transvaginal sonography for the early detection of ovarian cancer and suggest how this technique may best be used to distinguish benign from malignant ovarian masses.


CONCLUSIONS
Microbubble-enhanced transvaginal sonography can enhance the evaluation of ovarian masses by early detection of tumor microvascularity.
Fleischer
Arthur C
AC
Department of Radiology and Imaging Sciences, Vanderbilt University Medical Center, Nashville, TN 37232-2675, USA. arthur.fleischer@vanderbilt.edu
Lyshchik
Andrej
A
Andreotti
Rochelle F
RF
Hwang
Misun
M
Jones
Howard W
HW
Fishman
David A
DA
D003287:Contrast Media; D005260:Female; D005466:Fluorocarbons; D006801:Humans; D021621:Imaging, Three-Dimensional; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging*; D010743:Phospholipids; D012680:Sensitivity and Specificity; D013459:Sulfur Hexafluoride; D018608:Ultrasonography, Doppler / Q000379:methods*
D003287:Contrast Media; D005466:Fluorocarbons; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride; C042852:perflutren