[Studies on the lowering blood sugar substances from agrimony].
OBJECTIVE
To isolate and identify the chemical constituents from the active section lowering blood sugar of agrimony.


METHODS
The compounds were separated by repeated silica gel, Sephadex LH-20 and HPLC chromatographies. The structures of compounds isolated were identified by analysis of their spectral data and chemical properties.


RESULTS
Nine compounds were isolated from the active section with lowering blood sugar of agrimony and their structures were identified as apigenin-7-O-3-D-glucopyranoside (1), catechin (2), quercetin (3), rutin (4), kaempferol-3-O-alpha-L-rhamnoside (5), Kampferol-3-O-beta-D-glucopyranoside (6), lutcolin-7-O-beta-D-glucopyranosidc (7), 19alpha, 24-dihydroxy ursolic acid (8), 3,3'-di-O-mcthyl ellagic acid4-O-beta-D-glucopyranoside (9).


CONCLUSIONS
Compounds 1, 7, 8, 9 are isolated from thia plant for the first time.
Zhang
Jian-Hong
JH
Department of Pharmacy, Guangdong Food and Drug Vocational College, Guangzhou 510520, China. zhangjh@gdyzy.edu.cn
Chen
You-Sheng
YS
D031981:Agrimonia / Q000737:chemistry*; D047310:Apigenin / Q000737:chemistry / Q000302:isolation & purification*; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D000097245:Ursolic Acid
D047310:Apigenin; D002392:Catechin; D006027:Glycosides; D007004:Hypoglycemic Agents; D011794:Quercetin; D014315:Triterpenes; D000097245:Ursolic Acid