title: Study on the mechanism of compound mistletoe fluidextract in relieving hypertension.
abstract: OBJECTIVE
  To observe the effect of fufang jisheng liujin gao (Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD).
  
  
  METHODS
  The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of niuhuang jiangya wan (Bezoar Hypertension-relieving Pills).
  
  
  RESULTS
  Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD.
  
  
  CONCLUSIONS
  The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.
authors.affiliation: Qilu Hospital of Shandong University, Jinan 250012, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Ye
authors.forename: Guang-zhong
authors.initials: GZ
authors.lastname: Du
authors.forename: Ai-qing
authors.initials: AQ
authors.lastname: Cui
authors.forename: Xiao-ting
authors.initials: XT
authors.lastname: Lu
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004195:Disease Models, Animal; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D014784:Mistletoe / Q000737:chemistry*; D051381:Rats; D011918:Rats, Inbred SHR
chemical_list: D004365:Drugs, Chinese Herbal