Hashimoto encephalopathy in a preschool girl.
Hashimoto encephalopathy is a steroid-responsive encephalopathy associated with elevated blood concentrations of antithyroid antibodies. The patients are usually euthyroid or mildly hypothyroid. The clinical picture is pleomorphic, presenting with variable symptoms ranging from behavioral and cognitive changes, myoclonus, seizures, pyramidal tract dysfunction, involuntary movements, and cerebellar signs to psychosis and coma, with relapsing and progressive course. The diagnosis is often overlooked at presentation but is crucial, given that this is a treatable disease. Described here, with a literature review, is the youngest patient reported to date with Hashimoto encephalopathy.
Castro-Gago
Manuel
M
Neuropediatric Service, Department of Pediatrics, University Hospital, Faculty of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain. manuel.castro.gago@usc.es
Gómez-Lado
Carmen
C
Maneiro-Freire
Mercedes
M
Eirís-Puñal
Jesús
J
Bravo-Mata
Manuel
M
D002675:Child, Preschool; D004569:Electroencephalography; D004660:Encephalitis / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans