Angiocentric glioma-like tumor of the midbrain.
Angiocentric glioma, a rare brain neoplasm with features of ependymal differentiation, has only recently been recognized as a distinct clinicopathological entity. To date, all reported cases have involved tumors in the cerebral hemispheres, and the majority have presented with seizures. The authors report the case of a 5-year-old girl who presented with several cranial neuropathies and mild gait disturbance. An exophytic neoplasm arising from the posterior midbrain and causing obstructive hydrocephalus was identified, and surgical resection revealed a neoplasm with features of angiocentric glioma.
Covington
Derek B
DB
Department of Neurological Surgery, Miller School of Medicine, University of Miami, and Miami Children's Hospital, Miami, FL 33155, USA.
Rosenblum
Marc K
MK
Brathwaite
Carole D
CD
Sandberg
David I
DI
D001707:Biopsy, Needle; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D020233:Gait Disorders, Neurologic / Q000175:diagnosis / Q000209:etiology*; D005910:Glioma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008636:Mesencephalon / Q000473:pathology* / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods; D018570:Risk Assessment; D016896:Treatment Outcome