Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde.
Hopkinson
Richard J
RJ
Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, UK.
Hamed
Refaat B
RB
Rose
Nathan R
NR
Claridge
Timothy D W
TD
Schofield
Christopher J
CJ
D004926:Escherichia coli / Q000235:genetics; D005557:Formaldehyde / Q000378:metabolism*; D006801:Humans; D056484:Jumonji Domain-Containing Histone Demethylases / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D007656:Ketoglutaric Acids / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D010455:Peptides / Q000138:chemical synthesis / Q000378:metabolism
D007656:Ketoglutaric Acids; D010455:Peptides; D005557:Formaldehyde; D056484:Jumonji Domain-Containing Histone Demethylases; C549811:KDM4E protein, human