Comparing insulins detemir and glargine in type 2 diabetes: more similarities than differences. Commentary.
The efficacy of either detemir or glargine is comparable in subjects with type 2 diabetes when combined with insulin aspart in a basal-bolus regimen. Subjects randomized to detemir used slightly higher daily insulin doses, but gained less weight on average than glargine-treated subjects.
Reynolds
L Raymond
LR
Division of Endocrinology and Molecular Medicine, University of Kentucky, Lexington, KY 40506, USA. lrreyn2@email.uky.edu
D000328:Adult; D006801:Humans; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000031:analogs & derivatives / Q000627:therapeutic use; D000069057:Insulin Detemir; D000069036:Insulin Glargine; D049528:Insulin, Long-Acting; D015337:Multicenter Studies as Topic; D016032:Randomized Controlled Trials as Topic
D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D000069057:Insulin Detemir; D000069036:Insulin Glargine; D049528:Insulin, Long-Acting