title: Patterns of loss of basic activities of daily living in Alzheimer patients: A cross-sectional study of the French REAL cohort.
abstract: OBJECTIVE
  To characterize loss of basic activities of daily living (BADL) in 687 Alzheimer's disease (AD) community-dwelling patients included in the French REAL cohort.
  
  
  METHODS
  Patients had mild to moderately severe AD, and the mean age was 77.8 years. Patterns of loss of the 6 BADL were described at inclusion using the Lawton scale.
  
  
  RESULTS
  With 6 binary BADL scores, each patient presented at inclusion a set of losses. For 53% of women, the sets of losses were included within each other or were identical, adding losses in physical ambulation, grooming, bathing, dressing, toilet and feeding, respectively. For 47% of men, a similar sequence was identified, with loss of dressing occurring secondly. A global cohesion of sets of losses was found for 87% of women and 86% of men. The Lawton scale is very useful for the assessment of AD patients.
authors.affiliation: Service de Médecine Gériatrique, AP-HP, Hôpital Sainte-Périne, Paris, France. laurent.lechowski@spr.aphp.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: Lechowski
authors.forename: Sophie
authors.initials: S
authors.lastname: Van Pradelles
authors.forename: Marine
authors.initials: M
authors.lastname: Le Crane
authors.forename: Lydie
authors.initials: L
authors.lastname: d'Arailh
authors.forename: Danièle
authors.initials: D
authors.lastname: Tortrat
authors.forename: Laurent
authors.initials: L
authors.lastname: Teillet
authors.forename: Bruno
authors.initials: B
authors.lastname: Vellas
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000453:epidemiology / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012959:Socioeconomic Factors