Primary progressive aphasia: clinical, imaging, and neuropathological findings.
Primary Progressive Aphasia (PPA) is a neurodegenerative disorder initially presenting with progressive language imapirment. This article provides a clinically oriented review of PPA. Different clinical presentations and imaging findings of 3 subtypes, agrammatic, semantic and logopenic, are presented. Underlying neuropathology, medical and social management aspects of these patients are reviewed.
Gliebus
Gediminas
G
Cognitive Neurology and Alzheimer's Disease Center, Northwestern University Feinberg School of Medicine, 320 East SuperiorStreet,Chicago, IL 60611, USA. g-gliebus@md.northwestern.edu
D000368:Aged; D001039:Aphasia, Broca / Q000000981:diagnostic imaging / Q000473:pathology / Q000523:psychology*; D018888:Aphasia, Primary Progressive / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology* / Q000523:psychology*; D006801:Humans; D007807:Language Tests; D009483:Neuropsychological Tests; D049268:Positron-Emission Tomography; D012660:Semantics; D013060:Speech