Endoscopic follow-up of 3 cases with gastrointestinal tract involvement of mantle cell lymphoma.
Gastrointestinal (GI) tract involvement of mantle cell lymphoma (MCL) presents as a variety of forms, ranging from multiple lymphomatous polyposis (MLP) to a slight mucosal change. We report 3 cases with GI tract involvement of MCL who were followed-up by endoscopy. The present study shows three new informations. MLP of the esophagus is rare, but it was observed in two of 3 patients who were extensively involved by MCL. Endoscopic follow-up in one patient suggested that lymphoma cells of MCL had invaded the lamina propria to submucosal layer before MLP developed. Two of the 3 cases showed a favorable clinical course with single-agent rituximab therapy.
Saito
Makoto
M
Department of Internal Medicine, Aiiku Hospital, Sapporo. ikyoku@aiiku-hp.or.jp
Mori
Akio
A
Irie
Tatsuro
T
Tanaka
Masanori
M
Morioka
Masanobu
M
Ozasa
Mariko
M
Kobayashi
Takahiko
T
Saga
Akiyoshi
A
Miwa
Kimiaki
K
Tanaka
Shinya
S
D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents / Q000627:therapeutic use; D018450:Disease Progression; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D000069283:Rituximab
D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D000069283:Rituximab