title: Effect of absorbent tetracycline-loaded membrane used in the reduction of periodontal pockets: an in vivo study.
abstract: This clinical study evaluated the influence of scaling and root planning (SRP), with and without the use of tetracycline-loaded bovine absorbent membrane, in the reduction of periodontal pockets according to 3 parameters: probing pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI). Twenty-four patients were selected totalizing 144 random teeth divided in 2 groups (n=72 teeth) - control (SRP) and experimental (SRP with tetracycline-loaded absorbent membrane). PPD, BOP and PI were determined before and 28 days after the treatment. In all patients, the PPD values at the end of the treatment were always lower than the baseline values. There was a reduction of the PI for both treatments, but it was more evident on the experimental group. In conclusion, the use of tetracycline-loaded absorbent membrane could result in a better prognosis compared to scaling and root planning after only 28 days of evaluation.
authors.affiliation: Department of Periodontology and Implantology, Dental School, Federal University of Uberlândia, Uberlândia, MG, Brazil.
authors.forename: Priscilla Barbosa Ferreira
authors.initials: PB
authors.lastname: Soares
authors.forename: Helder Henrique Machado
authors.initials: HH
authors.lastname: de Menezes
authors.forename: Marina de Melo
authors.initials: MM
authors.lastname: Naves
authors.forename: Eulázio Mikio
authors.initials: EM
authors.lastname: Taga
authors.forename: Denildo
authors.initials: D
authors.lastname: de Magalhães
mesh_terms: D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002417:Cattle; D003773:Dental Plaque / Q000517:prevention & control; D003774:Dental Plaque Index; D012534:Dental Scaling; D016503:Drug Delivery Systems; D005260:Female; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000188:drug therapy*; D013752:Tetracycline / Q000008:administration & dosage*
chemical_list: D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial; D013752:Tetracycline