title: Severe leptospirosis in hospitalized patients, Guadeloupe.
abstract: We evaluated prognostic factors for leptospirosis in 168 consecutive hospitalized patients in Guadeloupe. Factors independently associated with severity included chronic hypertension or chronic alcoholism, late initiation of antibacterial therapy, abnormal chest auscultation results, icterus, oligoanuria, disorders of consciousness, elevated aspartate aminotransferase levels, hyperamylasemia, and Leptospira interrogans serovar Icterohemorrhagiae.
authors.affiliation: Guyane University, Guadeloupe, French West Indies. cecile.herrmann@chu-guadeloupe.fr
authors.forename: Cecile
authors.initials: C
authors.lastname: Herrmann-Storck
authors.forename: Magalie
authors.initials: M
authors.lastname: Saint-Louis
authors.forename: Tania
authors.initials: T
authors.lastname: Foucand
authors.forename: Isabelle
authors.initials: I
authors.lastname: Lamaury
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Deloumeaux
authors.forename: Guy
authors.initials: G
authors.lastname: Baranton
authors.forename: Maurice
authors.initials: M
authors.lastname: Simonetti
authors.forename: Natacha
authors.initials: N
authors.lastname: Sertour
authors.forename: Muriel
authors.initials: M
authors.lastname: Nicolas
authors.forename: Jacques
authors.initials: J
authors.lastname: Salin
authors.forename: Muriel
authors.initials: M
authors.lastname: Cornet
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D007022:Hypotension / Q000150:complications / Q000401:mortality; D041383:Leptospira interrogans serovar icterohaemorrhagiae / Q000302:isolation & purification; D007922:Leptospirosis / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors