Long-term results of gastric bypass surgery in morbidly obese type 1 diabetes patients.
BACKGROUND
Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented.


METHODS
Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery.


RESULTS
Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6-0.95 to 0.3-0.83 IU/kg, and absolute reduction in HbA(1c) was 3-4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted.


CONCLUSIONS
RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.
Czupryniak
Leszek
L
Diabetology and Metabolic Diseases Department, Barlicki University Hospital No 1, Kopcinskiego 22, Lodz, Poland. leszek.czupryniak@umed.lodz.pl
Wiszniewski
Marcin
M
Szymański
Dariusz
D
Pawłowski
Maciej
M
Loba
Jerzy
J
Strzelczyk
Janusz
J
D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications / Q000601:surgery*; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D009767:Obesity, Morbid / Q000097:blood / Q000150:complications / Q000601:surgery*; D055815:Young Adult