Synthesis of 3,6-branched oligomannoside fragments of the mannan from Candida albicans cell wall corresponding to the antigenic factor 4.
3-Aminopropyl glycosides of 3,6-branched penta- and hexamannoside fragments of the cell wall mannan from Candida albicans, corresponding to the antigenic factor 4, have been synthesized. Subsequent coupling of both oligosaccharides with BSA using the squarate procedure provided corresponding neoglycoconjugates.
Karelin
Alexander A
AA
Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
Tsvetkov
Yury E
YE
Paulovicová
Lucia
L
Bystrický
Slavomír
S
Paulovicová
Ema
E
Nifantiev
Nikolay E
NE
D000818:Animals; D000946:Antigens, Fungal / Q000737:chemistry* / Q000276:immunology; D002176:Candida albicans / Q000166:cytology* / Q000276:immunology*; D002240:Carbohydrate Sequence; D002417:Cattle; D002473:Cell Wall / Q000737:chemistry*; D000939:Epitopes / Q000737:chemistry / Q000276:immunology; D006027:Glycosides / Q000737:chemistry; D008351:Mannans / Q000737:chemistry* / Q000276:immunology; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000378:metabolism
D000946:Antigens, Fungal; D000939:Epitopes; D006027:Glycosides; D008351:Mannans; D009844:Oligosaccharides; C028569:oligomannoside; D012710:Serum Albumin, Bovine