Differentiation of influenza B virus lineages Yamagata and Victoria by real-time PCR.
Since the 1970s, influenza B viruses have diverged into two antigenically distinct virus lineages called the Yamagata and Victoria lineages. We present the first real-time PCR assay for virus lineage differentiation to supplement classical antigenic analyses. The assay was successfully applied to 310 primary samples collected in Germany from 2007 to 2009.
Biere
Barbara
B
Robert Koch Institut, FG17 Influenza/Respiratorische Viren, Nordufer 20, 13353 Berlin, Germany. biereb@rki.de
Bauer
Bettina
B
Schweiger
Brunhilde
B
D005858:Germany; D006801:Humans; D009981:Influenza B virus / Q000145:classification* / Q000235:genetics*; D007251:Influenza, Human / Q000821:virology; D016133:Polymerase Chain Reaction / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*