title: Inferior caval vein thrombosis owing to compression of focal nodular hyperplasia: surgical resection after shrinkage by hepatic artery embolization.
abstract: The purpose of this study was to investigate the results of a staged treatment of symptomatic focal nodular hyperplasia (FNH), consisting of first embolization and then resection. A 36-year-old woman presented with pulmonary embolism caused by an inferior caval vein thrombosis owing to external compression by FNH in liver segment I (5.2 x 6.7 cm). She was treated with anticoagulants. The FNH lesion was first reduced by radiologic embolization of the feeding branch of the right hepatic artery. A 41% size reduction was obtained, and the symptoms disappeared. FNH resection was performed 5(1/2) months later. The thrombus had disappeared, and the anticoagulant therapy could be stopped perioperatively. A symptomatic FNH lesion was treated successfully in two stages.
authors.affiliation: Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands. c.h.p.arts@umcutrecht.nl
authors.forename: Cora H P
authors.initials: CH
authors.lastname: Arts
authors.forename: Richard
authors.initials: R
authors.lastname: van Hillegersberg
authors.forename: Gerard A P
authors.initials: GA
authors.lastname: de Kort
authors.forename: Frans L
authors.initials: FL
authors.lastname: Moll
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002763:Cholecystectomy; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D017075:Laser Coagulation; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000601:surgery*; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery / Q000628:therapy*
chemical_list: D000925:Anticoagulants