Peritumoral edema after stereotactic radiosurgery for meningioma.
Peritumoral edema induced by radiosurgery after the treatment of intracranial meningioma has been reported and its mechanism remains unclear. A 65-year-old woman presented with a history of intermittent dizziness. A CT scan and MRI of the brain revealed an extra-axial space-occupying lesion in the left frontal region. She was treated by stereotactic radiosurgery (SRS). Seven months later, the patient began experiencing general weakness and drowsiness. She developed peritumoral edema around the left frontal tumor. Similarly, a 55-year-old woman complained of unstable gait and dizziness 1 month prior to admission. A CT scan and MRI of the brain revealed an extra-axial space-occupying lesion in the right posterior temporal region. Six months after SRS, this patient experienced deteriorated consciousness and general weakness. Peritumoral edema in the right temporal region was noted. We report these two patients, discuss possible causes and review the relevant literature.
Hsieh
Cheng-Ta
CT
Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Kung Road, Neihu District, Taipei 114, Taiwan.
Tsai
Jo-Ting
JT
Chang
Li-Ping
LP
Lin
Jia-Wei
JW
Chang
Steven D
SD
Ju
Da-Tong
DT
D000368:Aged; D001929:Brain Edema / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology; D016634:Radiosurgery / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed