[Analysis of liver function index and clinical characters in 122 patients with acute hepatitis E virus coinfection with other hepatitis virus].
OBJECTIVE
To compare the liver function index and clinical characters in 122 patients with acute hepatitis E virus overlapping with other infection.


METHODS
The liver function index and clinical characters of 122 patients with acute hepatitis E virus overlapping infection and 40 patients with acute hepatitis E were retrospectively analyzed.


RESULTS
No significant differences of ALT, AST, TBIL, DBIL were found between acute hepatitis E groups and overlapping infection hepatitis A or hepatitis B (P > 0.05). However, there were significant differences of Albumin (ALB) and Globulin (GLO) were found between acute hepatitis E groups and overlapping infection hepatitis B (P < 0.01). In acute hepatitis E overlapping infected hepatitis B or hepatitis A patients, more and severe complications were also observed.


CONCLUSIONS
The patients with acute Hepatitis E virus, especially Hepatitis E virus overlapping infection, need to pay more clinical monitor, prevent complication early and lower death rates.
Tian
Shu-Ping
SP
Center of the Clinical laboratory, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China. tianshuping1018@sohu.com
Yu
Yan-Hua
YH
Xin
Yong-Mei
YM
Zhao
Xiu-Ying
XY
Sun
Gui-Zhen
GZ
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000378:metabolism; D005260:Female; D005916:Globulins / Q000378:metabolism; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D016751:Hepatitis E / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000378:metabolism; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
D000418:Albumins; D005916:Globulins