title: Congenital adrenal hyperplasia: Results of medical therapy on appearance of external genitalia.
abstract: OBJECTIVE
  Girls with congenital adrenal hyperplasia show a variable degree of genital masculinization at birth. Antenatal dexamethazone treatment for the mother is known to reduce the severity of this condition. There are however few data on the effect of postnatal steroid therapy on the cosmetic appearance of the external genitalia.
  
  
  METHODS
  We report the appearance of the external genitalia of three girls with classical congenital adrenal hyperplasia followed up by steroid therapy alone.
  
  
  RESULTS
  Growth of the labia majora and a relative reduction in clitoral size improved the appearance of the external genitalia in these three girls.
  
  
  CONCLUSIONS
  There seems to be improvement in the external appearance of genitalia with postnatal steroid therapy. This could allay parental concerns and help in the planning of corrective surgery peripubertally with the informed consent of the child.
authors.affiliation: Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, Delhi 110029, India.
authors.forename: B
authors.initials: B
authors.lastname: Kulshreshtha
authors.forename: R
authors.initials: R
authors.lastname: Khadgawat
authors.forename: M
authors.initials: M
authors.lastname: Eunice
authors.forename: A C
authors.initials: AC
authors.lastname: Ammini
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy* / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D005836:Genitalia, Female / Q000187:drug effects* / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007223:Infant
chemical_list: D005938:Glucocorticoids