Frontoparietal activity with minimal decision and control in the awake macaque at 7 T.
Previous imaging work has identified a frontoparietal network in the human brain involved in many different cognitive functions, as well as in simple updates of attended information. To determine whether a similar network is present in the monkey brain and direct future electrophysiological recordings, we examined the activation of frontoparietal areas during visual stimulation in the awake, fixating monkey. We measured activity with BOLD fMRI in three animals and analyzed the data individually for each animal and at group level. We found reliable activations in lateral prefrontal and parietal areas, even though task-related decision making was minimal, as a response to simple update of visual information. These activations were significant for each individual animal, as well as at group level. Similar to human imaging results the update of visual input was enough to activate an extensive network of frontoparietal cortex in the macaque brain, a network which is normally associated with complex cognitive control processes.
Stoewer
Steffen
S
Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, Tuebingen, Germany. steffen.stoewer@tuebingen.mpg.de
Ku
Shih-Pi
SP
Goense
Jozien
J
Steudel
Thomas
T
Logothetis
Nikos K
NK
Duncan
John
J
Sigala
Natasha
N
D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000473:pathology*; D001931:Brain Mapping / Q000379:methods; D003071:Cognition; D004594:Electrophysiology / Q000379:methods; D005133:Eye Movements; D005625:Frontal Lobe / Q000473:pathology; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008251:Macaca; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010296:Parietal Lobe / Q000473:pathology; D010775:Photic Stimulation / Q000379:methods