title: Comparison of acquisition parameters and breast dose in digital mammography and screen-film mammography in the American College of Radiology Imaging Network digital mammographic imaging screening trial.
abstract: OBJECTIVE
  The purpose of our study was to compare the technical performance of full-field digital mammography (FFDM) and screen-film mammography.
  
  
  METHODS
  The American College of Radiology Imaging Network Digital Mammographic Imaging Screening Trial enrolled 49,528 women to compare FFDM and screen-film mammography for screening. For quality assurance purposes, technical parameters including breast compression force, compressed breast thickness, mean glandular dose, and the number of additional views needed for complete breast coverage were recorded and analyzed for both FFDM and screen-film mammography on approximately 10% of study subjects at each site.
  
  
  RESULTS
  Technical data were compiled on 5,102 study subjects at 33 sites. Clean data were obtained for 4,366 (88%) of those cases. Mean compression force was 10.7 dN for screen-film mammography and 10.1 dN for FFDM (5.5% difference, p < 0.001). Mean compressed breast thickness was 5.3 cm for screen-film mammography and 5.4 cm for FFDM (1.7% difference, p < 0.001). Mean glandular dose per view averaged 2.37 mGy for screen-film mammography and 1.86 mGy for FFDM, 22% lower for digital than screen-film mammography, with sizeable variations among digital manufacturers. Twelve percent of screen-film mammography cases required more than the normal four views, whereas 21% of FFDM cases required more than the four normal views to cover all breast tissue. When extra views were included, mean glandular dose per subject was 4.15 mGy for FFDM and 4.98 mGy for screen-film mammography, 17% lower for FFDM than screen-film mammography.
  
  
  CONCLUSIONS
  Our results show that differences between screen-film mammography and FFDM in compression force and indicated compressed breast thickness were small. On average, FFDM had 22% lower mean glandular dose than screen-film mammography per acquired view, with sizeable variations in average FFDM doses by manufacturer.
authors.affiliation: Department of Radiology, University of Colorado-Denver, Aurora, 80045, USA. edward.hendrick@gmail.com
authors.forename: R Edward
authors.initials: RE
authors.lastname: Hendrick
authors.forename: Etta D
authors.initials: ED
authors.lastname: Pisano
authors.forename: Alice
authors.initials: A
authors.lastname: Averbukh
authors.forename: Catherine
authors.initials: C
authors.lastname: Moran
authors.forename: Eric A
authors.initials: EA
authors.lastname: Berns
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Yaffe
authors.forename: Benjamin
authors.initials: B
authors.lastname: Herman
authors.forename: Suddhasatta
authors.initials: S
authors.lastname: Acharyya
authors.forename: Constantine
authors.initials: C
authors.lastname: Gatsonis
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D011786:Quality Control; D012372:ROC Curve; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D015203:Reproducibility of Results; D014481:United States; D014962:X-Ray Film