title: Open-wedge high tibial osteotomy in varus knee osteoarthritis: a 5-year prospective cohort study.
abstract: BACKGROUND
  High tibial osteotomy (HTO) is an accepted procedure to correct the varus deformity to restore the mechanical axis, reduce pain and delay the need for arthroplasty, especially in young and active patients. Nowadays, the opening wedge HTO is preferable than the close one.
  
  
  OBJECTIVE
  To evaluate the clinical results and complications of medial compartment gonarthrosis treated with opening wedge HTO.
  
  
  METHODS
  The prospective cohort study of 45 knees in 40 consecutive patients (32 women, 8 men, 46-81 years) with medial compartment osteoarthritis of the knee underwent medial open-wedge HTO and TomoFix between February 2004 and February 2009 (average follow-up of 46.1 +/- 11.5 months).
  
  
  RESULTS
  During the follow-up period, patients experienced significantly greater pain relief from baseline pain-intensity scores (all p < 0.001). The mean femorotibial angle (FTA) at the preoperative, 1-year and more than 2-year follow-up were 171.27 +/- 9.41 degrees of varus, 182.91 +/- 4.93 and 182.45 +/- 5.74 degrees of valgus, in orderly.
  
  
  CONCLUSIONS
  Medial opening wedge HTO with TomoFix provided intraoperative desirable correction and sufficient stabilization. Early mobilization, rehabilitation and maintenance of correction alignment until bony union occurred without instrument failure.
authors.affiliation: Orthopaedic Division, Charoenkrung-Pracharak Hospital, Bangkok, Thailand. jpong140@yahoo.co.th
authors.forename: Buntoeng
authors.initials: B
authors.lastname: Pongsoipetch
authors.forename: Chaichana
authors.initials: C
authors.lastname: Tantikul
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy / Q000009:adverse effects / Q000379:methods*; D011446:Prospective Studies; D016059:Range of Motion, Articular; D013977:Tibia / Q000601:surgery*; D016896:Treatment Outcome