title: Are transition zone biopsies necessary in transrectal ultrasound-guided transperineal prostate biopsy protocol? Results of a Chinese population-based study.
abstract: OBJECTIVE
  The purpose of this study was to determine the utility of routine transperineal transition zone (TZ) biopsies.
  
  
  METHODS
  A total of 1028 consecutive patients underwent transrectal ultrasound-guided prostate biopsies for the first time. Sextant biopsies and additional two-core TZ biopsies were performed.
  
  
  RESULTS
  Prostate cancer detection rate was increased by sampling two additional cores from TZ.
  
  
  CONCLUSIONS
  Transition zone biopsies might be reserved to improve the detection rate of prostate cancer in transperineal biopsy protocol.
authors.affiliation: Department of Ultrasound in Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, PR China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Yunkai
authors.forename: Chen
authors.initials: C
authors.lastname: Yaqing
authors.forename: Wang
authors.initials: W
authors.lastname: Ren
authors.forename: Zhou
authors.initials: Z
authors.lastname: Yongchang
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000379:methods / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology*; D012007:Rectum / Q000000981:diagnostic imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted / Q000379:methods / Q000706:statistics & numerical data*; D014463:Ultrasonography / Q000379:methods / Q000706:statistics & numerical data*