title: [Meteoadaptogenic properties of antihypoxic drugs].
abstract: The meteoadaptogenic properties of antihypoxic drugs (citoflavin, reamberin, hypoxen, mexidol) have been studied in climate thermobarocomplex Tabai (Japan) on a group of healthy volunteers aged 20 - 24. It is established that all these drugs produce a meteoadaptogenic effect, the degree of which depends on the environment conditions (overcooling, overheating, hypobaric hypoxia). Citoflavin optimized the functional state in both cold and hot climate as well as under hypobaric hypoxia conditions. Mexidol can be classified as an adaptogen and both menthal and physical actoprotector under overcooling or hypobaric hypoxia conditions (highlands). Hypoxen, which positively affects the psychological component of the functional state and enhances psychomotor activity, can be used for rapid adaptation to a hot climate. Reamberine significantly increases the physical component of the functional state under cold conditions and can be considered as a psychomotor enhancer and adaptogen for the regions of cold climate. Therefore, all the drugs studied (citoflavin, reamberin, hypoxen, mexidol) can be recommended as the means of activation, support, and recovery of physical and psychological efficiency under rapidly changing environment conditions.
authors.forename: V P
authors.initials: VP
authors.lastname: Ganapol'skiĭ
authors.forename: P D
authors.initials: PD
authors.lastname: Shabanov
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects* / Q000502:physiology; D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage*; D002980:Climate; D006801:Humans; D008297:Male
chemical_list: D000975:Antioxidants