Congenital adrenal hyperplasia: Results of medical therapy on appearance of external genitalia.
OBJECTIVE
Girls with congenital adrenal hyperplasia show a variable degree of genital masculinization at birth. Antenatal dexamethazone treatment for the mother is known to reduce the severity of this condition. There are however few data on the effect of postnatal steroid therapy on the cosmetic appearance of the external genitalia.


METHODS
We report the appearance of the external genitalia of three girls with classical congenital adrenal hyperplasia followed up by steroid therapy alone.


RESULTS
Growth of the labia majora and a relative reduction in clitoral size improved the appearance of the external genitalia in these three girls.


CONCLUSIONS
There seems to be improvement in the external appearance of genitalia with postnatal steroid therapy. This could allay parental concerns and help in the planning of corrective surgery peripubertally with the informed consent of the child.
Kulshreshtha
B
B
Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, Delhi 110029, India.
Khadgawat
R
R
Eunice
M
M
Ammini
A C
AC
D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy* / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D005836:Genitalia, Female / Q000187:drug effects* / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007223:Infant
D005938:Glucocorticoids