title: Prevalence of von Willebrand disease in dogs from Sao Paulo State, Brazil.
abstract: The aims of the current study were to assess the prevalence of von Willebrand disease (vWD) in dogs from the region of Botucatu, São Paulo State, Brazil, and to evaluate laboratory tests to diagnose this disease. The study included 350 dogs of various ages, different breeds, and both sexes. Dogs included in the study had no historical or clinical evidence of abnormal bleeding. von Willebrand factor antigen (vWFAg), buccal mucosal bleeding time, activated partial thromboplastin time, and factor VIII activity were evaluated in their ability to diagnose vWD. The prevalence of vWD in dogs was 1.43% in the Botucatu region of Brazil. Determination of vWFAg was the best laboratory test to diagnose vWD.
authors.affiliation: School of Veterinary Medicine and Animal Science at São Paulo State University, Departamento de Clínica Veterinária, Laboratório Clínico Veterinário, Distrito de Rubião Jr., s/n, Botucatu, São Paulo, CEP 18618-000, Caixa postal 560, Brazil.
authors.forename: Cláudio Roberto S
authors.initials: CR
authors.lastname: Mattoso
authors.forename: Regina Kiomi
authors.initials: RK
authors.lastname: Takahira
authors.forename: Suzane Lílian
authors.initials: SL
authors.lastname: Beier
authors.forename: João Pessoa
authors.initials: JP
authors.lastname: Araújo
authors.forename: José Eduardo
authors.initials: JE
authors.lastname: Corrente
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D004283:Dog Diseases / Q000453:epidemiology*; D004285:Dogs; D005260:Female; D008297:Male; D015995:Prevalence; D014842:von Willebrand Diseases / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D014841:von Willebrand Factor / Q000276:immunology
chemical_list: D014841:von Willebrand Factor