Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns.
A recent shortage of erythromycin ointment has resulted in the use of alternative agents for newborn ocular infection prophylaxis in the United States. We report a series of 26 newborns in whom a characteristic periocular ulcerative dermatitis developed after gentamicin ointment administration at 2 Philadelphia hospitals.
Binenbaum
Gil
G
Division of Ophthalmology, Children's Hospital of Philadelphia and the University of Pennsylvania, 9-MAIN, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA. binenbaum@email.chop.edu
Bruno
Christie J
CJ
Forbes
Brian J
BJ
Snyder
MaryAnn
M
Mollen
Thomas J
TJ
Schmidt
Barbara
B
Peterside
Iyalla
I
D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D019072:Antibiotic Prophylaxis / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology; D005141:Eyelid Diseases / Q000139:chemically induced*; D005148:Facial Dermatoses / Q000139:chemically induced*; D005260:Female; D005839:Gentamicins / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009824:Ointments; D015143:Philadelphia
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D009824:Ointments