title: Spontaneous coronary artery dissection and acute myocardial infarction during pregnancy.
abstract: Spontaneous coronary artery dissection is a rare cause of infarction in the general population, but a common cause of myocardial infarction during pregnancy, and even nowadays carries a high risk of mortality. We describe the case of a 31-year-old primigravida who presented during the 34th week of pregnancy with the chief complaint of chest pain and was found to suffer from myocardial infarction. She was otherwise healthy and had no known risk factors for coronary artery disease. The patient was treated conservatively with nitrates, aspirin, heparin and beta-blockers, eventually sustained a large myocardial infarction and, after an initial period of instability, remained asymptomatic. A week later she delivered 3 healthy babies. A coronary angiogram performed 3 months after the initial event revealed an extensive obstructive dissection of the circumflex coronary artery. The decision whether to pursue percutaneous coronary intervention, surgical revascularisation or appropriate medical therapy, is based on clinical presentation, the extent of the dissection, and the amount of ischaemic myocardium at risk. Cardiologists must be aware of this rare entity during pregnancy or postpartum, since early diagnosis and treatment are crucial for the survival of the mother and the foetus.
authors.affiliation: Cardiology Department, Veria Hospital, Aristotle University of Thessaloniki, Greece. ivogia@otenet.gr
authors.forename: Ioannis
authors.initials: I
authors.lastname: Vogiatzis
authors.forename: Stavros
authors.initials: S
authors.lastname: Hadjimiltiades
authors.forename: Vasilios
authors.initials: V
authors.lastname: Sachpekidis
authors.forename: Georgios
authors.initials: G
authors.lastname: Parcharidis
mesh_terms: D000328:Adult; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular