title: Management of acute hematogenous osteomyelitis in children.
abstract: In children, osteomyelitis is primarily hematogenous in origin and acute in nature. The principal cause of osteomyelitis in children is Staphylococcus aureus, and both the epidemiology and pathogenesis of S. aureus infections, including osteomyelitis, have changed in recent years owing to the emergence of community-associated methicillin-resistant S. aureus. This review focuses on advances in the diagnosis and overall management of acute hematogenous osteomyelitis in children with these changes in mind.
authors.affiliation: Department of Pediatrics and Department of Microbiology and Immunology, University of Arkansas for Medical Sciences and the Arkansas Children's Hospital, Little Rock, AR 72205, USA. hariknada@uams.edu
authors.forename: Nada S
authors.initials: NS
authors.lastname: Harik
authors.forename: Mark S
authors.initials: MS
authors.lastname: Smeltzer
mesh_terms: D000208:Acute Disease; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D010019:Osteomyelitis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery
chemical_list: D000890:Anti-Infective Agents