title: Intraoperative assessment of epithelial and non-epithelial ovarian tumors: a 7-year review.
abstract: OBJECTIVE
  To determine the accuracy of frozen section diagnosis of ovarian tumors and to discuss discrepant diagnostic cases.
  
  
  METHODS
  932 ovarian tumors were submitted for frozen section examination. Cases with a significant diagnostic discrepancy between the intraoperative and the final histological diagnosis were reviewed.
  
  
  RESULTS
  The sensitivity of frozen section diagnosis for benign, borderline and malignant epithelial tumors was 98.82%, 98.97% and 87.66% and the specificity 98.01%, 97.06% and 100%, respectively. There were 27 cases with diagnostic discrepancy. All non teratomatous sex cord/stromal and germ cell tumors were correctly diagnosed while a diagnostic discrepancy was observed in teratomatous tumors.
  
  
  CONCLUSIONS
  Frozen section diagnosis is a reliable method for the surgical management of an ovarian mass. Nevertheless, care should be taken for large tumors measuring > 20 cm in diameter, particularly when the intraoperative diagnosis reveals an epithelial borderline tumor or a teratomatous tumor with an extensive neural component.
authors.affiliation: Department of Pathology, University of Athens, Greece. epavlaki@med.uoa.gr
authors.forename: K
authors.initials: K
authors.lastname: Pavlakis
authors.forename: I
authors.initials: I
authors.lastname: Messini
authors.forename: T
authors.initials: T
authors.lastname: Vrekoussis
authors.forename: P
authors.initials: P
authors.lastname: Yiannou
authors.forename: T
authors.initials: T
authors.lastname: Panoskaltsis
authors.forename: Z
authors.initials: Z
authors.lastname: Voulgaris
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007432:Intraoperative Period; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D055815:Young Adult