title: Histologic evaluation of the use of membrane, bone graft, and MTA in apical surgery.
abstract: The aim of this study was to evaluate the periapical healing after the use of membrane, bone graft, and mineral trioxide aggregate (MTA) in apical surgery of dogs' teeth. Apical lesions were induced in 48 roots of 6 dogs after coronal access and pulpal removal. Apical surgery consisted of osteotomy with trephine bur for the standardization of the critical surgical cavities, followed by apicoectomy, curettage, preparation of the root-end cavities with the aid of the ultrasonic device, and retrofilling with MTA. The surgical sites were divided into: group 1-filled with blood; group 2-filled with blood and recovered with membrane; group 3-filled with bone graft; and group 4-filled with bone graft and recovered with membrane. The results showed that the inflammatory infiltrate, the periapical healing process, and the behavior of MTA was the same in all groups, including the mineralization stimulation. It was concluded that the use of membranes and bone graft materials isolated or associated in apical surgery did not alter the periapical healing process after the root-end filling with MTA.
authors.affiliation: Department of Endodontics, Araçatuba School of Dentistry, São Paulo State University, Araçatuba, Brazil.
authors.forename: Pedro Felício Estrada
authors.initials: PF
authors.lastname: Bernabé
authors.forename: João Eduardo
authors.initials: JE
authors.lastname: Gomes-Filho
authors.forename: Luciano Tavares Angelo
authors.initials: LT
authors.lastname: Cintra
authors.forename: Marcelo Juliano
authors.initials: MJ
authors.lastname: Moretto
authors.forename: Carolina Simonetti
authors.initials: CS
authors.lastname: Lodi
authors.forename: Mauro Juvenal
authors.initials: MJ
authors.lastname: Nery
authors.forename: José Arlindo
authors.initials: JA
authors.lastname: Otoboni Filho
authors.forename: Elói
authors.initials: E
authors.lastname: Dezan
mesh_terms: D017607:Aluminum Compounds; D000818:Animals; D001047:Apicoectomy; D001861:Bone Regeneration; D016025:Bone Transplantation; D017610:Calcium Compounds; D004285:Dogs; D004338:Drug Combinations; D016557:Guided Tissue Regeneration, Periodontal; D008297:Male; D008567:Membranes, Artificial; D010087:Oxides; D010485:Periapical Periodontitis / Q000601:surgery*; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials; D017640:Silicates
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D008567:Membranes, Artificial; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate