A thioether-rich crown-based highly selective fluorescent sensor for Hg(2+) and Ag(+) in aqueous solution.
A new fluorescent sensor 1, based on the naphthalimide chromophore and thioether-rich crown receptor, exhibited dual signaling behaviors for Hg(2+) and Ag(+) in aqueous solution. Upon addition of Hg(2+), the fluorescence intensity enhanced in a linear fashion with a quantum yield increase of about 5-fold. Moreover, with the 1-Hg(2+) complex, Ag(+) was easily recognized by a marked fluorescence quenching. The living cells image experiments demonstrate the value of sensor 1 in fluorescent visualization of Hg(2+) ions in biological systems.
Chen
Tao
T
Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
Zhu
Weiping
W
Xu
Yufang
Y
Zhang
Shenyi
S
Zhang
Xiaojun
X
Qian
Xuhong
X
D047248:Crown Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D004785:Environmental Pollutants / Q000032:analysis* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008628:Mercury / Q000032:analysis* / Q000737:chemistry; D008856:Microscopy, Fluorescence; D053644:Naphthalimides / Q000138:chemical synthesis / Q000737:chemistry*; D012834:Silver / Q000032:analysis* / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D013440:Sulfides / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D047248:Crown Compounds; D004785:Environmental Pollutants; D005456:Fluorescent Dyes; C548439:N-propyl-4-(2-(1,4,7,10-tetrathia-13-azacyclopentadecane)ethylamino)-1,8-naphthalimide; D053644:Naphthalimides; D013440:Sulfides; D014867:Water; D012834:Silver; D008628:Mercury