title: Trauma and dentinogenesis: a case report.
abstract: BACKGROUND
  After a traumatic injury to the upper central incisors of a 7-year-old patient, avulsion of tooth #9 and pulp exposure after crown fracture of tooth #8 were managed.
  
  
  METHODS
  After immediate replacement of tooth #9 in its socket, teeth were splinted for 3 weeks. No endodontic treatment was performed on tooth #9, but pulp capping was performed with mineral trioxide aggregate (Pro Root MTA; Dentsply Maillefer, Ballaigues, Switzerland) on #8, and both teeth were restored with composite resin. The teeth were monitored every 3 months for 2 years.
  
  
  RESULTS
  At 24 months, both teeth responded positively to electrometric tests and roots showed normal development, but an abnormal reduction in the size of the root canal space of tooth#8 was observed.
  
  
  CONCLUSIONS
  Based on these observations, we discuss odontoblast behavior in the context of the stage of dentinogenesis and the probable disturbance of regulation of the physiologic dentinogenic secretory processes in the pathologic situation.
authors.affiliation: Laboratoire de Physiopathologie Orale Moléculaire, INSERM, Centre de Recherche des Cordeliers, Paris, France. srs635@bham.ac.uk
authors.forename: Stéphane
authors.initials: S
authors.lastname: Simon
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Lumley
authors.forename: Paul R
authors.initials: PR
authors.lastname: Cooper
authors.forename: Ariane
authors.initials: A
authors.lastname: Berdal
authors.forename: Pierre
authors.initials: P
authors.lastname: Machtou
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Smith
mesh_terms: D002648:Child; D003785:Dental Pulp Capping / Q000379:methods*; D003810:Dentinogenesis / Q000502:physiology*; D005971:Glutamates / Q000627:therapeutic use; D006147:Guanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007180:Incisor / Q000293:injuries* / Q000502:physiology; D008297:Male; D008437:Maxilla; D000068437:Pemetrexed; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D014084:Tooth Avulsion / Q000628:therapy*; D014082:Tooth Fractures / Q000628:therapy*; D014090:Tooth Replantation; D016896:Treatment Outcome
chemical_list: D005971:Glutamates; D012387:Root Canal Filling Materials; D000068437:Pemetrexed; D006147:Guanine