[Choroidal nevi].
We describe the clinical, angiographic, and echographic aspects of benign choroidal nevi and their differential diagnosis represented mostly by congenital hypertrophy of the pigment epithelium, melanocytoma, and mostly suspicious nevi. Suspicious nevi are defined by the presence of visual symptoms, the presence of orange pigment on the surface, the presence of subretinal fluid sometimes more visible on OCT, the presence of pin-points on angiograms, a thickness of more than 2mm, or a diameter of more than 7 mm. The proximity of the optic disk has also been shown to be a risk factor in several studies. A review of the literature showed that these factors that make the nevus suspicious are associated with a risk of malignant transformation and metastasis, which is correlated to the number of risk factors present at diagnosis. This is why it is important to recommend close follow-up of these lesions with a check-up every 3 months (and radiotherapeutic treatment in case of growth) or early treatment if there are several risk factors and if the lesion is away from the posterior pole.
Desjardins
L
L
Institut Curie, 26, rue d'Ulm, 75248 Paris cedex 5. Laurence.desjardins@curie.net
D000359:Aftercare; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D006801:Humans; D008545:Melanoma / Q000175:diagnosis; D009367:Neoplasm Staging; D009508:Nevus, Pigmented / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D009887:Ophthalmoscopy; D011379:Prognosis; D012307:Risk Factors; D041623:Tomography, Optical Coherence