Highly regio- and stereoselective intermolecular tandem reaction to synthesize chloro-substituted 1,3-butadienes.
A palladium catalyzed highly regio- and stereoselective intermolecular tandem reaction of alkynes, CuCl(2) and alkenes by a sequence of chloropalladation/Heck reaction to produce chloro-substituted 1,3-dienes is achieved.
Huang
Jing-Mei
JM
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, China. chehjm@scut.edu.cn
Dong
Yi
Y
Wang
Xu-Xiao
XX
Luo
Hui-Chao
HC
D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D002713:Chlorine / Q000737:chemistry*; D054879:Halogenation; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism
D000475:Alkenes; D000480:Alkynes; D002070:Butadienes; D002713:Chlorine; D010165:Palladium; C031763:1,3-butadiene