title: [Successful therapy with etanercept in relapsing polychondritis].
abstract: Relapsing polychondritis is a rare autoimmune disease associated with inflammation and destruction of cartilage and connective tissue.We report on a patient with a severe form of this disease that had a progressive and complicated course despite administration of a number of disease-modifying anti-rheumatic drugs.Finally, therapy with the TNF-alpha-antagonist etanercept was initiated, which led to a considerable decrease in disease activity. This case is further evidence for the efficiency of TNF-alpha-antagonists in relapsing polychondritis.
authors.affiliation: Klinik für Innere Medizin und Rheumatologie, Fachklinik Bad Bentheim, 48455, Bad Bentheim, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Schräder
authors.forename: J
authors.initials: J
authors.lastname: Lohmann
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage*; D008297:Male; D011081:Polychondritis, Relapsing / Q000188:drug therapy* / Q000517:prevention & control*; D018124:Receptors, Tumor Necrosis Factor / Q000008:administration & dosage / Q000037:antagonists & inhibitors*; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept