title: Psychological impact of isotretinoin treatment in patients with moderate and severe acne.
abstract: Acne patients are subject to different degree of psychosocial distress. The emotional impact of acne vulgaris due to disfigurement caused by the disease is undisputed. Most common reactions to the acne are depression and anxiety. The use of isotretinoin, one of the most effective options in acne treatment, increases depression symptoms. The aim of this study was to investigate the psychological status of the patients with moderate to severe acne and to compare patients treated with isotretinoin with patients treated with vitamin C. A total of 85 patients suffering from acne vulgaris were included in the study. The results of this study do not find a significant correlation between the use of isotretinoin and the psychological effects of the drug.
authors.affiliation: Department for Dermatology and Venerology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina. simicdubravka@gmail.com
authors.forename: Dubravka
authors.initials: D
authors.lastname: Simić
authors.forename: Mirna
authors.initials: M
authors.lastname: Situm
authors.forename: Edita
authors.initials: E
authors.lastname: Letica
authors.forename: Jasna Zeljko
authors.initials: JZ
authors.lastname: Penavić
authors.forename: Maja Vurnek
authors.initials: MV
authors.lastname: Zivković
authors.forename: Teo
authors.initials: T
authors.lastname: Tomić
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000523:psychology*; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control*; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use; D017523:Croatia; D003863:Depression / Q000209:etiology / Q000517:prevention & control*; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies; D012720:Severity of Illness Index
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin; D001205:Ascorbic Acid