title: Determination of antibiotics in sewage from hospitals, nursery and slaughter house, wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China.
abstract: Sewage samples from 4 hospitals, 1 nursery, 1 slaughter house, 1 wastewater treatment plant and 5 source water samples of Chongqing region of Three Gorge Reservoir were analyzed for macrolide, lincosamide, trimethoprim, fluorouinolone, sulfonamide and tetracycline antibiotics by online solid-phase extraction and liquid chromatography-tandem mass spectrometry. Results showed that the concentration of ofloxacin (OFX) in hospital was the highest among all water environments ranged from 1.660 microg/L to 4.240 microg/L and norfloxacin (NOR, 0.136-1.620 microg/L), ciproflaxacin (CIP, ranged from 0.011 microg/L to 0.136 microg/L), trimethoprim (TMP, 0.061-0.174 microg/L) were commonly detected. Removal range of antibiotics in the wastewater treatment plant was 18-100% and the removal ratio of tylosin, oxytetracycline and tetracycline were 100%. Relatively higher removal efficiencies were observed for tylosin (TYL), oxytetracycline (OXY) and tetracycline (TET)(100%), while lower removal efficiencies were observed for Trimethoprim (TMP, 1%), Epi-iso-chlorotetracycline (EICIC, 18%) and Erythromycin-H(2)O (ERY-H(2)O, 24%). Antibiotics were removed more efficiently in primary treatment compared with those in secondary treatment.
authors.affiliation: Department of Environmental Hygiene, School of Military Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Chang
authors.forename: Michael T
authors.initials: MT
authors.lastname: Meyer
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Liu
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhao
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Ji-an
authors.initials: JA
authors.lastname: Chen
authors.forename: Zhiqun
authors.initials: Z
authors.lastname: Qiu
authors.forename: Lan
authors.initials: L
authors.lastname: Yang
authors.forename: Jia
authors.initials: J
authors.lastname: Cao
authors.forename: Weiqun
authors.initials: W
authors.lastname: Shu
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D002681:China; D008506:Medical Waste / Q000032:analysis*; D012722:Sewage / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification
chemical_list: D000900:Anti-Bacterial Agents; D008506:Medical Waste; D012722:Sewage; D014874:Water Pollutants, Chemical