title: Incidence of hospitalization due to community-acquired rotavirus infection: a 12-year study (1996-2008).
abstract: The incidence of hospitalization for acute gastroenteritis (AGE) is a useful parameter to assess the utility of the new rotavirus vaccines in high-income countries. Children hospitalized for AGE were identified by searching hospital discharge data and the records of the microbiology laboratory of Hospital Donostia. Rotavirus antigen was investigated in 96.1% of the 1114 children aged 1 month to <5 years hospitalized for AGE in the study period. Nearly 40% were rotavirus positive (44.9% of the 798 children aged 1 month to <2 years), with G1[P8] being the predominant genotype. The mean annual incidence rate of hospitalization due to rotavirus AGE was 29.8 and 63.7 cases/10 000 inhabitants in the <5 and <2 years age groups, respectively, in 1996-1999, decreasing to 13.6 and 27.4 cases/10 000 inhabitants in <5 and <2 years age groups, respectively, in 2002-2005 (P<0.001). This decrease coincided with a significant increase in the consumption of oral rehydration solutions.
authors.affiliation: Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain. carlosgustavo.cillaeguiluz@osakidetza.net
authors.forename: G
authors.initials: G
authors.lastname: Cilla
authors.forename: M
authors.initials: M
authors.lastname: Gomariz
authors.forename: M
authors.initials: M
authors.lastname: Montes
authors.forename: M I
authors.initials: MI
authors.lastname: Mendiburu
authors.forename: E G
authors.initials: EG
authors.lastname: Pérez-Yarza
authors.forename: E
authors.initials: E
authors.lastname: Pérez-Trallero
mesh_terms: D000208:Acute Disease; D016009:Chi-Square Distribution; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000821:virology*; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D012400:Rotavirus Infections / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology