title: Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents.
abstract: In this tutorial review, an effort towards presentation of a comprehensive account of the recent developments on various kinds of artemisinin derivatives including artemisinin dimers, trimers and tetramers has been made and their efficacy towards malaria parasites and different cancer cells lines was compared with that of artemisinins, and various other anti-malarial and anti-cancer drugs. It is expected that this review will provide first-hand information on artemisinin chemistry to organic/medicinal chemists, and pharmacologists working on anticancer and anti-malarial drug development.
authors.affiliation: Natural Products Chemistry Division, North-East Institute of Science & Technology, Assam, Jorhat-785006, India.
authors.forename: Devdutt
authors.initials: D
authors.lastname: Chaturvedi
authors.forename: Abhishek
authors.initials: A
authors.lastname: Goswami
authors.forename: Partha Pratim
authors.initials: PP
authors.lastname: Saikia
authors.forename: Nabin C
authors.initials: NC
authors.lastname: Barua
authors.forename: Paruchuri G
authors.initials: PG
authors.lastname: Rao
mesh_terms: D000962:Antimalarials / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D037621:Artemisinins / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D019281:Dimerization
chemical_list: D000962:Antimalarials; D000970:Antineoplastic Agents; D037621:Artemisinins