Insights on novel biologically active natural products: 7-isopentenyloxycoumarin.
7-Isopentenyloxycoumarin is a prenyloxyphenylpropanoid derivative found in low concentration in a restricted number of plant families (Apiaceae, Asteraceae, and Rutaceae). Synthetic schemes were recently developed enabling sufficient quantities of the title coumarin to be obtained in order to evidence its valuable biological effects, mainly as an anti-cancer agent. The aim of this review is to examine the phytochemical and pharmacological properties of this compound.
Epifano
Francesco
F
Dipartimento di Scienze del Farmaco, Università "G. D 'Annunzio" di Chieti-Pescara, Via dei Vestini 31, Chieti Scalo, Italy, 66013. fepifano@unich.it
Pelucchini
Caroline
C
Curini
Massimo
M
Genovese
Salvatore
S
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D016587:Antimutagenic Agents / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D010944:Plants / Q000737:chemistry*
C461443:7-isopentenyloxycoumarin; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D016587:Antimutagenic Agents; D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins; D009125:Muscle Relaxants, Central