title: Tumours of the submandibular salivary gland: a clinicopathologic review of cases over a 17-year period.
abstract: OBJECTIVE
  This study presents a clinicopathologic review of cases of submandibular salivary gland tumours at the Lagos University Teaching Hospital, Nigeria, over a period of 17 years.
  
  
  METHODS
  The records of all patients with histological diagnosis of submandibular salivary gland tumours at the Lagos University Teaching Hospital over a period of 17 years (January 1990 to December 2006) were retrospectively reviewed. Parameters studied were; age and gender of patients, symptoms and duration of symptoms, and histological diagnosis.
  
  
  RESULTS
  A total of 36 patients with submandibular gland tumours were seen during the period. Male-to-female ratio was 1.8:1 (male=23, female=13). Mean age (+/- SD) at presentation was 43 (+/- 19) years (age range, 17-84 years). There were 19 malignant tumours and 17 benign ones. Pleomorphic adenoma (36.1%) was the most frequent tumours, followed by adenoid cystic carcinoma (11.1%), anaplastic carcinoma (11.1%) and malignant lymphoma (11.1%). Patients with histological diagnosis of malignant tumours were significantly older than those with benign tumours (p = 0.01). Most patients (80.6%) presented with painless swelling.
  
  
  CONCLUSIONS
  Malignant submandibular salivary gland tumours were slightly more than the benign ones in the studied population. Painful swelling or ulceration is indicative of a malignant submandibular gland tumour
authors.affiliation: Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Nigeria. lanreadeyemo@yahoo.com
authors.forename: W L
authors.initials: WL
authors.lastname: Adeyemo
authors.forename: O F
authors.initials: OF
authors.lastname: Ajayi
authors.forename: C C
authors.initials: CC
authors.lastname: Anunobi
authors.forename: M O
authors.initials: MO
authors.lastname: Ogunlewe
authors.forename: A L
authors.initials: AL
authors.lastname: Ladeinde
authors.forename: O G
authors.initials: OG
authors.lastname: Omitola
authors.forename: F B
authors.initials: FB
authors.lastname: Abdulkareem
mesh_terms: D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013365:Submandibular Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology; D055815:Young Adult