Severe leptospirosis in hospitalized patients, Guadeloupe.
We evaluated prognostic factors for leptospirosis in 168 consecutive hospitalized patients in Guadeloupe. Factors independently associated with severity included chronic hypertension or chronic alcoholism, late initiation of antibacterial therapy, abnormal chest auscultation results, icterus, oligoanuria, disorders of consciousness, elevated aspartate aminotransferase levels, hyperamylasemia, and Leptospira interrogans serovar Icterohemorrhagiae.
Herrmann-Storck
Cecile
C
Guyane University, Guadeloupe, French West Indies. cecile.herrmann@chu-guadeloupe.fr
Saint-Louis
Magalie
M
Foucand
Tania
T
Lamaury
Isabelle
I
Deloumeaux
Jacqueline
J
Baranton
Guy
G
Simonetti
Maurice
M
Sertour
Natacha
N
Nicolas
Muriel
M
Salin
Jacques
J
Cornet
Muriel
M
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D007022:Hypotension / Q000150:complications / Q000401:mortality; D041383:Leptospira interrogans serovar icterohaemorrhagiae / Q000302:isolation & purification; D007922:Leptospirosis / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors