title: New cardenolides from the stem bark of Trewia nudiflora.
abstract: Phytochemical investigation of the stem bark of Trewia nudiflora led to the isolation of two new cardenolides, trewianin (1) and trewioside (2), along with scopoletin (3) and indole-3-carboxylic acid (4). Structures were established by 1D- and 2D NMR spectroscopy, HR-MS analysis, and by comparison with literature data.
authors.affiliation: Natural Products Research Laboratories, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
authors.forename: Jamil A
authors.initials: JA
authors.lastname: Shilpi
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Gray
authors.forename: Véronique
authors.initials: V
authors.lastname: Seidel
mesh_terms: D002298:Cardenolides / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D007211:Indoles / Q000302:isolation & purification; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012603:Scopoletin / Q000302:isolation & purification
chemical_list: D002298:Cardenolides; D007211:Indoles; C553619:trewianin; C553620:trewioside; C012382:indole-3-carboxylic acid; D012603:Scopoletin