title: Pegylated interferon-alpha for treating chronic hepatitis E virus infection after liver transplantation.
abstract: This study assessed the effect of a 3-month course of pegylated interferon-alpha-2a (Peg-IFN-alpha-2a) in 3 liver transplant patients with chronic active hepatitis E. A virological response was sustained for 6 and 5 months in 2 patients after Peg-IFN-alpha-2a therapy was completed. A relapse was observed in the third patient.
authors.affiliation: Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire, Toulouse, France. kamar.n@chu-toulouse.fr
authors.forename: Nassim
authors.initials: N
authors.lastname: Kamar
authors.forename: Lionel
authors.initials: L
authors.lastname: Rostaing
authors.forename: Florence
authors.initials: F
authors.lastname: Abravanel
authors.forename: Cyril
authors.initials: C
authors.lastname: Garrouste
authors.forename: Laure
authors.initials: L
authors.lastname: Esposito
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cardeau-Desangles
authors.forename: Jean Michel
authors.initials: JM
authors.lastname: Mansuy
authors.forename: Janick
authors.initials: J
authors.lastname: Selves
authors.forename: Jean Marie
authors.initials: JM
authors.lastname: Peron
authors.forename: Philippe
authors.initials: P
authors.lastname: Otal
authors.forename: Fabrice
authors.initials: F
authors.lastname: Muscari
authors.forename: Jacques
authors.initials: J
authors.lastname: Izopet
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D016751:Hepatitis E / Q000188:drug therapy*; D006521:Hepatitis, Chronic / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011994:Recombinant Proteins; D055502:Secondary Prevention
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; C100416:peginterferon alfa-2a