title: The effect of renal transplantation for end-stage renal disease on female sexual function and depression.
abstract: BACKGROUND
  Studies have suggested that women with end-stage renal disease (ESRD) had higher risk of sexual dysfunction than healthy women.
  
  
  OBJECTIVE
  To prospectively determine the effect of renal transplantation for ESRD on female sexual function and depression.
  
  
  METHODS
  During a 5-year period, the study included 21 sexually active women who underwent renal transplantation for ESRD at a single university hospital. After obtaining demographic characteristics, female sexual function was evaluated with a detailed 19-item questionnaire (The Female Sexual Function Index, FSFI), and depression was assessed using Beck Depression Inventory (BDI) scale.
  
  
  METHODS
  In all women, FSFI and BDI scores were compared before and after the renal transplantation surgery.
  
  
  RESULTS
  The mean age of the women was 35.04 ± 9.6 years, and mean follow-up duration after renal transplantation was 27.5 ± 20.4 months. Mean total sexual function score increased from 17.57 ± 7.07 to 25.3 ± 3.28, revealing significant difference (P = 0.001). Compared with preoperative period, sexual function domains including sexual desire (P = 0.001), arousal (P = 0.001), lubrication (P = 0.003), orgasm (P = 0.001), satisfaction (P = 0.001), and pain (P = 0.02) significantly improved after renal transplantation. Mean BDI score significantly decreased from 17.91 ± 8.56 to 3 ± 4.17 after renal transplantation (P = 0.001).
  
  
  CONCLUSIONS
  Successful renal transplantation may improve female sexual functions and depression. Therefore, life quality increases as sexual functions and depression improve after the renal transplantation surgery.
authors.affiliation: Departments of Urology, University of Mersin School of Medicine, Mersin, Turkey.
authors.forename: Elife
authors.initials: E
authors.lastname: Kettaş
authors.forename: Filiz
authors.initials: F
authors.lastname: Cayan
authors.forename: Ozan
authors.initials: O
authors.lastname: Efesoy
authors.forename: Erdem
authors.initials: E
authors.lastname: Akbay
authors.forename: Selahittin
authors.initials: S
authors.lastname: Cayan
mesh_terms: D000328:Adult; D003863:Depression / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000601:surgery*; D016030:Kidney Transplantation; D011446:Prospective Studies; D011788:Quality of Life; D012735:Sexual Dysfunction, Physiological / Q000209:etiology / Q000628:therapy*; D020018:Sexual Dysfunctions, Psychological / Q000209:etiology / Q000628:therapy*; D011795:Surveys and Questionnaires; D014421:Turkey / Q000453:epidemiology