title: M-mode echocardiographic changes in growing beagles.
abstract: Heart growth in 6 female beagle dogs was measured by using M-mode echocardiography at 4, 7, 10, 13, 17, and 21 mo of age. The same 6 dogs were evaluated throughout the study to establish when cardiac development ends in this breed. The following parameters were measured during systole and diastole: left ventricle posterior wall thickness, interventricular septal thickness, left ventricular internal dimension, left atrial dimension during ventricular systole, aortic root dimension at end diastole, E-point to septal separation, left ventricular preejection period, ejection time of the left ventricular outflow, and time between the cessation and onset of the mitral inflow intervals. The percentage of the left ventricle posterior wall thickening, fractional shortening, ejection fraction, left ventricular end systolic and end-diastolic volumes, ratio of the left atrial dimension to aortic root dimension, and the Tei index of myocardial performance were calculated. The heart rate was measured by cardiac auscultation. The influence of ageing on each echocardiographic parameter and relationships with body weight and surface were studied. Results show that cardiac development in female beagles can be considered finished by the age of 1 y, perhaps as soon as 7 mo. The cardiac indexes studied were unaffected by the age and corporal dimensions, confirming the usefulness of these parameters for evaluating cardiac functionality alterations independent of a dog's age and body weight or surface area.
authors.affiliation: Biomedicine Institute, University of León, León, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Diez-Prieto
authors.forename: M Belén
authors.initials: MB
authors.lastname: García-Rodríguez
authors.forename: M Angeles
authors.initials: MA
authors.lastname: Ríos-Granja
authors.forename: María J
authors.initials: MJ
authors.lastname: Cano-Rábano
authors.forename: Marina
authors.initials: M
authors.lastname: Peña-Penabad
authors.forename: Carlos C
authors.initials: CC
authors.lastname: Pérez-García
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001835:Body Weight / Q000502:physiology; D004283:Dog Diseases / Q000000981:diagnostic imaging; D004285:Dogs / Q000033:anatomy & histology / Q000254:growth & development*; D004452:Echocardiography / Q000662:veterinary*; D005260:Female; D006321:Heart / Q000033:anatomy & histology*; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000662:veterinary