title: Insights on novel biologically active natural products: 7-isopentenyloxycoumarin.
abstract: 7-Isopentenyloxycoumarin is a prenyloxyphenylpropanoid derivative found in low concentration in a restricted number of plant families (Apiaceae, Asteraceae, and Rutaceae). Synthetic schemes were recently developed enabling sufficient quantities of the title coumarin to be obtained in order to evidence its valuable biological effects, mainly as an anti-cancer agent. The aim of this review is to examine the phytochemical and pharmacological properties of this compound.
authors.affiliation: Dipartimento di Scienze del Farmaco, Università "G. D 'Annunzio" di Chieti-Pescara, Via dei Vestini 31, Chieti Scalo, Italy, 66013. fepifano@unich.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Epifano
authors.forename: Caroline
authors.initials: C
authors.lastname: Pelucchini
authors.forename: Massimo
authors.initials: M
authors.lastname: Curini
authors.forename: Salvatore
authors.initials: S
authors.lastname: Genovese
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D016587:Antimutagenic Agents / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D010944:Plants / Q000737:chemistry*
chemical_list: C461443:7-isopentenyloxycoumarin; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D016587:Antimutagenic Agents; D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins; D009125:Muscle Relaxants, Central