title: A case of Brugada syndrome presenting with incessant polymorphic ventricular tachycardia.
abstract: Brugada syndrome, an inherited arrhythmogenic cardiac disease, manifests with ST-segment changes in the right precordial leads, right bundle block pattern, and susceptibility to ventricular tachyarrhythmias and sudden death. The only established therapy for this disease is prevention of sudden death by implantation of a defibrillator. Herein we describe a case of a patient who presented with incessant ventricular tachycardia (VT) and syncope and who had a type 1 Brugada pattern on ECG. The patient was successfully treated with quinidine, after which the classically described type 2 and 3 patterns emerged.
authors.affiliation: Section of Cardiology, Department of Medicine, Baylor College of Medicine, 1504 Taub Loop, Houston, TX 77030, USA.
authors.forename: Harn-Cherng
authors.initials: HC
authors.lastname: Shiue
authors.forename: Vijay G
authors.initials: VG
authors.lastname: Divakaran
authors.forename: Nasser M
authors.initials: NM
authors.lastname: Lakkis
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D053840:Brugada Syndrome / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D002037:Bundle-Branch Block; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D006801:Humans; D008297:Male; D011802:Quinidine / Q000627:therapeutic use; D013575:Syncope; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D013997:Time Factors
chemical_list: D000889:Anti-Arrhythmia Agents; D011802:Quinidine