title: Measuring health-related quality of life in children living in HIV/AIDS-affected families in rural areas in Yunnan, China: Preliminary reliability and validity of the Chinese version of PedsQL 4.0 generic core scales.
abstract: OBJECTIVE
  To investigate the preliminary reliability and validity of the Chinese Mandarin version of the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales in a sample of general children and children living in HIV/AIDS-affected families.
  
  
  METHODS
  The PedsQL 4.0 was administered to 116 children aged 8-18 years from HIV/AIDS-affected families and 115 of their caregivers. The questionnaire was also administered to a control group of 109 children and 107 of their caregivers.
  
  
  RESULTS
  Most of the self-report and proxy-report scales in both groups exceeded the reliability standard of 0.70, whereas the self-report emotional functioning and school functioning subscales were slightly less than 0.70. On average, children living in HIV/AIDS-affected families scored significantly lower than the control group. The level of agreement between self-reports and proxy reports was low. Correlations were higher on average for the younger age group than for the older age group.
  
  
  CONCLUSIONS
  The Chinese Mandarin version of PedsQL 4.0 is a valid and reliable instrument for use with children living in HIV families. The health-related quality of life for children living in HIV families is lower than children from ordinary families.
authors.affiliation: National Center for AIDS/STD Control and Prevention, Beijing, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Xu
authors.forename: Zunyou
authors.initials: Z
authors.lastname: Wu
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Yan
authors.forename: Keming
authors.initials: K
authors.lastname: Rou
authors.forename: Song
authors.initials: S
authors.lastname: Duan
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005190:Family; D005195:Family Relations; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011788:Quality of Life; D012424:Rural Population; D011795:Surveys and Questionnaires