[Expressions of eNOS and cytochrome P450 in the testis of sexually mature SD rats and their significance].
OBJECTIVE
To explore the expressions of endothelial nitric oxide synthase (eNOS) and cytochrome P450 (aromatase) in the testis of sexually mature male SD rats and their significance.


METHODS
Eighteen male SD rats, 6 five-week, 6 seven-week and 6 ten-week old, were selected for this study. Paraffin sections of the left testis were made and the expressions of eNOS and P450 observed by the immunohistochemical ABC method.


RESULTS
Positive expressions of eNOS and P450 were found to be + + +, + and + + in the Leydig cells of the five-week, seven-week and ten-week old rats, respectively, and they were also observed in a few spermatocytes, though with no regularity.


CONCLUSIONS
In the Leydig cells of sexually mature male SD rats, eNOS and P450 are differently expressed in different stages of sexual maturation, and they are correlated as well.
Ren
Ya-ping
YP
Department of Histology and Embryology, Guilin Medical College, Guilin, Guangxi 541004, China. yapingrengl@163.com
Sun
Li
L
Shao
Xiao-yun
XY
Chen
Jun
J
Xiong
Bin
B
Nong
Lin-lin
LL
D000818:Animals; D001141:Aromatase / Q000378:metabolism*; D008297:Male; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012741:Sexual Maturation; D013737:Testis / Q000378:metabolism*
D052250:Nitric Oxide Synthase Type III; C496316:Nos3 protein, rat; D001141:Aromatase