[Bilateral testicular tumors caused by congenital adrenal rest hyperplasia].
OBJECTIVE
Testicular tumors are a rare condition associated with congenital adrenal hyperplasia (CAH), originated from intratesticular adrenal rest tumors, and they are rarely associated with malignant tumors. Their histological differentiation from Leydig-cell tumors is quite difficult, which would lead to inappropriate orchiectomies. Thus the objective of this report was to present this diagnostic dilemma.


METHODS
Reported the case of 16-yr-old boy with previous diagnosis of CAH with bilateral testicular enlargement who was recommended to be submitted to a bilateral orchiectomy.


RESULTS
Considering this findings, it was decided to treat conventionally with prednisone with significant reduction of testicular volume, and normalization of androgens levels.


CONCLUSIONS
This case shows the importance of intratesticular adrenal rest tumors in the differential diagnosis of testicular tumors. Cautious approach during investigation and treatment are recommended to avoid inappropriate orchiectomies.
Fernandes
Virginia Oliveira
VO
Serviço de Endocrinologia e Diabetes, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
Barros
Antonio Iran Souza
AI
Quidute
Ana Rosa Pinto
AR
Montenegro
Ana Paula Dias Rangel
AP
Fontenele
Eveline Gadelha Pereira
EG
Sales
Ana Paula Abreu Martins
AP
Montenegro
Renan Magalhães
RM
Ferreira
Francisco Valdeci de Almeida
FV
Montenegro
Renan Magalhães
RM
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000473:pathology*; D000314:Adrenal Rest Tumor / Q000473:pathology*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007984:Leydig Cell Tumor / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology*
D018931:Antineoplastic Agents, Hormonal; D011241:Prednisone