title: Comparative outcomes among the problem areas of interpersonal psychotherapy for depression.
abstract: BACKGROUND
  Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success.
  
  
  METHODS
  Patients meeting DSM-IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17-item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM-IV Personality Disorders.
  
  
  RESULTS
  Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates.
  
  
  CONCLUSIONS
  With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians.
authors.affiliation: Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Levenson
authors.forename: E
authors.initials: E
authors.lastname: Frank
authors.forename: Y
authors.initials: Y
authors.lastname: Cheng
authors.forename: P
authors.initials: P
authors.lastname: Rucci
authors.forename: C A
authors.initials: CA
authors.lastname: Janney
authors.forename: P
authors.initials: P
authors.lastname: Houck
authors.forename: R N
authors.initials: RN
authors.lastname: Forgione
authors.forename: H A
authors.initials: HA
authors.lastname: Swartz
authors.forename: J M
authors.initials: JM
authors.lastname: Cyranowski
authors.forename: A
authors.initials: A
authors.lastname: Fagiolini
mesh_terms: D000293:Adolescent; D000328:Adult; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D011613:Psychotherapy / Q000379:methods*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult