title: [The effect of the expression and influence of MMP-9 on prognosis of nasal polyps].
abstract: OBJECTIVE
  To study the expression of MMP-9 and eosinophils in nasal polyps and its influence on the prognosis.
  
  
  METHODS
  Study the expression of MMP-9 and EOS on the tissue of nasal polyps of patients who were cured or recurrent and normal nasal mucosa (NM) by immunohistochemistry and HE staining.
  
  
  RESULTS
  In the patients of recurrent group (Group B), the expression of MMP-9 was much stronger than that of good prognosis group (Group A) and NM. The MMP-9 was stronger in the eosinophil nasal polyps than that of non-eosinophil groups. The percentage of EOS in Group A was 16.67%, while 62.50% in the Group B.
  
  
  CONCLUSIONS
  The stronger expression of MMP-9 on Group B and eosinophil group indicated that MMP-9 might affect the prognosis of nasal polyps through inducing the number of EOS in the mucosa. MMP-9 may be one of the risk factors for the relapse of nasal polyps.
authors.affiliation: Department of Otolaryngology, the Third Xiangya Hospital, Central South University, Chan-gsha, 410013, China.
authors.forename: Jiangbo
authors.initials: J
authors.lastname: Chen
authors.forename: Tiansheng
authors.initials: T
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004804:Eosinophils / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D020780:Matrix Metalloproteinase 9 / Q000378:metabolism*; D009297:Nasal Mucosa / Q000378:metabolism; D009298:Nasal Polyps / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D011379:Prognosis; D012008:Recurrence
chemical_list: D020780:Matrix Metalloproteinase 9