A case of hypersensitivity to mosquito bite associated with Epstein-barr viral infection and natural killer cell lymphocytosis.
Hypersensitivity to mosquito bites (HMB) is a disorder characterized by a necrotic skin reaction and generalized symptoms subsequent to mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer cell leukemia/lymphoma. We describe here a Korean child who had HMB associated with chronic EBV infection and natural killer cell lymphocytosis. A 5-yr-old boy was suffered from necrotic skin lesions on the right ear lobe. Type A EB virus was detected from hlood cells and bone marrow biospy recognized hemophagocyrosis.
Roh
Eui Jung
EJ
Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea.
Chung
Eun Hee
EH
Chang
Young Pyo
YP
Myoung
Na Hye
NH
Jee
Young Koo
YK
Seo
Min
M
Kang
Jin Han
JH
D000818:Animals; D002675:Child, Preschool; D009033:Culicidae / Q000276:immunology*; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000175:diagnosis*; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000175:diagnosis*; D007299:Insect Bites and Stings / Q000150:complications / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D008218:Lymphocytosis / Q000150:complications / Q000175:diagnosis*; D008297:Male; D016133:Polymerase Chain Reaction