The Achilles heel of endothelin receptor therapy for pulmonary arterial hypertension.
Corris
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Langleben
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D
D000077300:Bosentan; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D065128:Endothelin Receptor Antagonists; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D007555:Isoxazoles / Q000494:pharmacology; D008099:Liver / Q000187:drug effects; D010641:Phenotype; D017466:Receptors, Endothelin / Q000627:therapeutic use*; D013449:Sulfonamides / Q000494:pharmacology; D013876:Thiophenes / Q000494:pharmacology
D065128:Endothelin Receptor Antagonists; D007555:Isoxazoles; D017466:Receptors, Endothelin; D013449:Sulfonamides; D013876:Thiophenes; C106276:sitaxsentan; D000077300:Bosentan