Churg-Strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings.
OBJECTIVE
The aim of this study was to compare the high-resolution computed tomographic findings between Churg-Strauss syndrome (CSS) and chronic eosinophilic pneumonia (CEP).


METHODS
We retrospectively reviewed the clinical records of 16 patients with CSS and 34 patients with CEP.


RESULTS
Twelve (35%) of the 34 patients with CEP had a history of asthma. Although the subpleural distribution of ground-glass opacities (GGOs) and consolidation was common both in CSS and CEP, the midzone distribution was more frequent in CSS (44%) than in CEP (12%). Centrilobular nodules within GGOs were significantly more frequent in CSS (56%) than in CEP (18%). In contrast, traction bronchiectasis associated with volume loss was demonstrated more frequently in CEP (74%) than in CSS (25%).


CONCLUSIONS
On high-resolution computed tomography, the presence of the midzone distribution and nodules within GGOs without traction bronchiectasis suggests CSS rather than CEP.
Furuiye
Masashi
M
Department of Integrated Pulmonology, Tokyo Medical and Dental University, Tokyo, Japan. furuie.pulm@tmd.ac.jp
Yoshimura
Nobuyuki
N
Kobayashi
Akiko
A
Tamaoka
Meiyo
M
Miyazaki
Yasunari
Y
Ohtani
Yoshio
Y
Miyake
Shuji
S
Inase
Naohiko
N
Yoshizawa
Yasuyuki
Y
D002908:Chronic Disease; D015267:Churg-Strauss Syndrome / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*