title: Oxa-azaspiro derivatives: a novel class of triple re-uptake inhibitors.
authors.affiliation: Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Via Fleming 4, 37135 Verona, Italy.
authors.forename: Michela
authors.initials: M
authors.lastname: Bettati
authors.forename: Paolo
authors.initials: P
authors.lastname: Cavanni
authors.forename: Romano
authors.initials: R
authors.lastname: Di Fabio
authors.forename: Beatrice
authors.initials: B
authors.lastname: Oliosi
authors.forename: Ornella
authors.initials: O
authors.lastname: Perini
authors.forename: Gunther
authors.initials: G
authors.lastname: Scheid
authors.forename: Giovanna
authors.initials: G
authors.lastname: Tedesco
authors.forename: Laura
authors.initials: L
authors.lastname: Zonzini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Micheli
mesh_terms: D001372:Aza Compounds / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D050483:Dopamine Plasma Membrane Transport Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D015394:Molecular Structure; D050484:Norepinephrine Plasma Membrane Transport Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D050486:Serotonin Plasma Membrane Transport Proteins / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D013141:Spiro Compounds / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D001372:Aza Compounds; D050483:Dopamine Plasma Membrane Transport Proteins; D050484:Norepinephrine Plasma Membrane Transport Proteins; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; D013141:Spiro Compounds; C493227:SLC6A2 protein, human; C493230:SLC6A4 protein, human