Th17 cytokines and vaccine-induced immunity.
T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in primary immune responses against infections is well documented, there is growing evidence that the Th17 lineage maybe critical for vaccine-induced memory immune responses against infectious diseases. Here, we summarize recent progress in our understanding of the role of IL-17 in vaccine-induced immunity.
Lin
Yinyao
Y
Department of Pediatrics and Immunology, University of Pittsburgh School of Medicine, PA, 15224, USA.
Slight
Samantha R
SR
Khader
Shabaana A
SA
D000818:Animals; D006801:Humans; D007110:Immunity, Active / Q000276:immunology*; D007156:Immunologic Memory / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D014611:Vaccination