title: Cryopreserved oocytes can serve as the treatment for secondary infertility: a novel model for egg donation.
abstract: OBJECTIVE
  To report the use of previously cryopreserved oocytes for the treatment of secondary infertility.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University-based IVF program.
  
  
  METHODS
  A 41-year-old woman with 18 months of secondary infertility and a previous history (age 38) of elective oocyte cryopreservation.
  
  
  METHODS
  Previously cryopreserved oocytes.
  
  
  METHODS
  Fertilization, embryo development, pregnancy, and outcome.
  
  
  RESULTS
  The patient achieved pregnancy and delivery following thaw of oocytes electively cryopreserved 39 months before use. Before thawing the oocyte, the patient attempted pregnancy naturally for 12 months, followed by two unsuccessful clomiphene citrate ovulation induction cycles with intrauterine insemination and one fresh IVF cycle resulting in a chromosomally abnormal twin gestation that aborted.
  
  
  CONCLUSIONS
  Although oocyte cryopreservation is still labeled an experimental procedure, this case demonstrates that oocyte cryopreservation used for electively deferred reproduction can subsequently serve in the treatment for secondary infertility when the patient becomes her own oocyte donor.
authors.affiliation: New York University Fertility Center, New York University School of Medicine, New York, New York 10016, USA. jaimeknopman@gmail.com
authors.forename: Jaime M
authors.initials: JM
authors.lastname: Knopman
authors.forename: Nicole
authors.initials: N
authors.lastname: Noyes
authors.forename: James A
authors.initials: JA
authors.lastname: Grifo
mesh_terms: D000328:Adult; D015925:Cryopreservation; D033001:Directed Tissue Donation; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D008954:Models, Biological; D018587:Oocyte Donation / Q000379:methods*; D009865:Oocytes; D011247:Pregnancy; D016649:Primary Ovarian Insufficiency / Q000150:complications / Q000628:therapy