Effect of menses on clearance of Y-chromosome in vaginal fluid: implications for a biomarker of recent sexual activity.
Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.
Brotman
Rebecca M
RM
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Melendez
Johan H
JH
Smith
Tukisa D
TD
Galai
Noya
N
Zenilman
Jonathan M
JM
D000328:Adult; D015415:Biomarkers; D016022:Case-Control Studies; D041322:Chromosomes, Human, Y / Q000502:physiology*; D003075:Coitus; D005260:Female; D006801:Humans; D008598:Menstruation / Q000502:physiology*; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D012749:Sexually Transmitted Diseases / Q000517:prevention & control; D014621:Vagina / Q000502:physiology*; D014626:Vaginal Smears
D015415:Biomarkers