title: Effect of menses on clearance of Y-chromosome in vaginal fluid: implications for a biomarker of recent sexual activity.
abstract: Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.
authors.affiliation: Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Brotman
authors.forename: Johan H
authors.initials: JH
authors.lastname: Melendez
authors.forename: Tukisa D
authors.initials: TD
authors.lastname: Smith
authors.forename: Noya
authors.initials: N
authors.lastname: Galai
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Zenilman
mesh_terms: D000328:Adult; D015415:Biomarkers; D016022:Case-Control Studies; D041322:Chromosomes, Human, Y / Q000502:physiology*; D003075:Coitus; D005260:Female; D006801:Humans; D008598:Menstruation / Q000502:physiology*; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D012749:Sexually Transmitted Diseases / Q000517:prevention & control; D014621:Vagina / Q000502:physiology*; D014626:Vaginal Smears
chemical_list: D015415:Biomarkers