title: [The frequency of detection of IgA, IgG and IgM antibodies to pertussis toxin in patients with respiratory tract infections in Poland].
abstract: Five hundred of results of commercial ELISA test (NovaLisa Bordetella pertussis, NovaTec) used in routine diagnosis of IgA, IgG and IgM antibodies to pertussis toxin in serum samples obtained from patients with respiratory tract infection were analyzed. The diagnostic level of IgA antibodies was observed in 54 (10.8%), IgG in 258 (51.6%) and IgM in 136 (27.2%) serum samples. The frequency of detection of the antibodies in children and adolescents increased with age reaching its peak among individuals with age range between 16-20 years. The results of our study showed also a high frequency of IgG antibodies to the pertussis toxin in the adults with respiratory tract infections. We also found statistical significant higher frequency of IgM antibodies, but not IgA and IgG, to pertussis toxin in women than in men.
authors.affiliation: Zakład Bakteriologii Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny. wrastawicki@pzh.gov.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Rastawicki
authors.forename: Natalia
authors.initials: N
authors.lastname: Rokosz
authors.forename: Marek
authors.initials: M
authors.lastname: Jagielski
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000907:Antibodies, Bacterial / Q000097:blood*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D037342:Pertussis Toxin / Q000276:immunology*; D010567:Pertussis Vaccine / Q000008:administration & dosage; D011044:Poland / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000097:blood / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D017678:Sex Distribution; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010567:Pertussis Vaccine; D037342:Pertussis Toxin