title: Acanthamoeba spp.: efficacy of Bioclen FR One Step, a povidone-iodine based system for the disinfection of contact lenses.
abstract: Pathogenic strains of Acanthamoeba are causative agents of a serious sight-threatening infection of the eye known as Acanthamoeba keratitis. The prevalence of this infection has risen in the past 20years, mainly due to the increase in number of contact lens wearers. Bioclen FR One Step (Ophtecs Corporation) is the only available povidone-iodine based system for the disinfection of silicone hydrogel lenses and soft contact lenses on the market. Bioclen FR has been proven to be highly effective against bacteria and fungi that can cause problems for contact lens users. In this study, Bioclen FR One Step was tested against three clinical Acanthamoeba isolates from contact lens cases. The results demonstrated that the tested Acanthamoeba clinical strains were sensitive to Bioclen FR One Step.
authors.affiliation: University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, S/N 38203 La Laguna, Tenerife, Canary Islands, Spain.
authors.forename: Carmen M
authors.initials: CM
authors.lastname: Martín-Navarro
authors.forename: Jacob
authors.initials: J
authors.lastname: Lorenzo-Morales
authors.forename: Atteneri
authors.initials: A
authors.lastname: López-Arencibia
authors.forename: Basilio
authors.initials: B
authors.lastname: Valladares
authors.forename: José E
authors.initials: JE
authors.lastname: Piñero
mesh_terms: D000048:Acanthamoeba / Q000187:drug effects*; D015823:Acanthamoeba Keratitis / Q000517:prevention & control*; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D018639:Contact Lens Solutions / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D011206:Povidone-Iodine / Q000494:pharmacology*
chemical_list: D000891:Anti-Infective Agents, Local; D018639:Contact Lens Solutions; D011206:Povidone-Iodine