title: In vivo modulation of HMGA2 expression.
abstract: While the biochemical role of the HMGA proteins has largely been elucidated in tissue culture, the majority of the insight as to their physiological functions in the processes of proliferation and development has been established in animal models of overexpression (transgenic) and null mice (knockouts). An emphasis has been placed on the HMGA2 studies which have defined its critical role in mesenchymal proliferation and differentiation.
authors.affiliation: HMGene, Inc. 675 US Highway One, North Brunswick, NJ 08902, USA.
authors.forename: Hena R
authors.initials: HR
authors.lastname: Ashar
authors.forename: Roland A
authors.initials: RA
authors.lastname: Chouinard
authors.forename: Madhavi
authors.initials: M
authors.lastname: Dokur
authors.forename: Kiran
authors.initials: K
authors.lastname: Chada
mesh_terms: D050156:Adipogenesis; D000818:Animals; D025743:HMGA2 Protein / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D008067:Lipoma / Q000378:metabolism; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D013091:Spermatogenesis; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D013737:Testis / Q000166:cytology / Q000378:metabolism
chemical_list: D025743:HMGA2 Protein