title: Dural metastases as a presentation of a Brenner tumor.
abstract: We present a 56-year-old woman who came to our institution with a 6-month history of intracranial hypertension. Imaging studies showed diffuse dural enhancement, multiple lytic bone lesions and a tumor in the left ovary. A meningeal biopsy was performed; however, during this procedure the patient developed profuse dural hemorrhage and middle cerebral artery territory infarction and died a few hours later. The autopsy revealed a disseminated Brenner tumor that was infiltrating the intracranial dura mater. At this site neovascularization, vascular infiltration by malignant cells and a desmoplastic reaction were all observed, perhaps rendering the patient more susceptible to a dural hemorrhage during the biopsy. To our knowledge, this is the first report of a Brenner tumor presenting as dural metastases.
authors.affiliation: Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Vasco de Quiroga No. 15, Col Secc XVI, Tlalpan, México City CP 1400, México. baicarjf@hotmail.com
authors.forename: José Fidel
authors.initials: JF
authors.lastname: Baizabal-Carvallo
authors.forename: Héctor Manuel
authors.initials: HM
authors.lastname: Barragán-Campos
authors.forename: Marlene
authors.initials: M
authors.lastname: Alonso-Juárez
authors.forename: Armando
authors.initials: A
authors.lastname: Gamboa-Domínguez
authors.forename: Francisco
authors.initials: F
authors.lastname: Gutierrez-Manjarréz
authors.forename: Claudia
authors.initials: C
authors.lastname: Caro-Sánchez
authors.forename: Guillermo
authors.initials: G
authors.lastname: García-Ramos
mesh_terms: D001948:Brenner Tumor / Q000556:secondary*; D004388:Dura Mater / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D019586:Intracranial Hypertension / Q000209:etiology; D007889:Leiomyoma / Q000150:complications / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications / Q000503:physiopathology / Q000556:secondary*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*