title: Endoscope-guided pneumatic dilation for treatment of esophageal achalasia.
abstract: Pneumatic dilation (PD) is considered to be the first line nonsurgical therapy for achalasia. The principle of the procedure is to weaken the lower esophageal sphincter by tearing its muscle fibers by generating radial force. The endoscope-guided procedure is done without fluoroscopic control. Clinicians usually use a low-compliance balloon such as Rigiflex dilator to perform endoscope-guided PD for the treatment of esophageal achalasia. It has the advantage of determining mucosal injury during the dilation process, so that a repeat endoscopy is not needed to assess the mucosal tearing. Previous studies have shown that endoscope-guided PD is an efficient and safe nonsurgical therapy with results that compare well with other treatment modalities. Although the results may be promising, long-term follow-up is required in the near future.
authors.forename: Seng-Kee
authors.initials: SK
authors.lastname: Chuah
authors.forename: Keng-Liang
authors.initials: KL
authors.lastname: Wu
authors.forename: Tsung-Hui
authors.initials: TH
authors.lastname: Hu
authors.forename: Wei-Chen
authors.initials: WC
authors.lastname: Tai
authors.forename: Chi-Sin
authors.initials: CS
authors.lastname: Changchien
mesh_terms: D001905:Botulinum Toxins / Q000008:administration & dosage; D004106:Dilatation; D004931:Esophageal Achalasia / Q000601:surgery*; D004945:Esophagoscopy; D006801:Humans; D007267:Injections; D010535:Laparoscopy; D016896:Treatment Outcome
chemical_list: D001905:Botulinum Toxins