title: The modern investigation and management of gastro-oesophageal reflux disease (GORD).
abstract: Gastro-oesophageal reflux disease results from impaired function of the LOS and acid clearance of the distal oesophagus. Most patients do not require investigation and respond either to lifestyle changes, antacid/alginates, H2A, PPI or a combination of these treatments. Surgery is only rarely indicated.
authors.affiliation: University College London. matthew.banks@uclh.nhs.uk
authors.forename: Matthew
authors.initials: M
authors.lastname: Banks
mesh_terms: D000863:Antacids / Q000627:therapeutic use*; D003679:Deglutition / Q000502:physiology*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D050782:Esophageal pH Monitoring; D004947:Esophagus / Q000503:physiopathology; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008019:Life Style; D008365:Manometry; D011312:Pressure; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D000863:Antacids; D054328:Proton Pump Inhibitors