title: Diagnostic accuracy of proximal caries by digital radiographs: an in vivo and in vitro comparative study.
abstract: OBJECTIVE
  The aim of this study was to evaluate if the diagnostic accuracy of proximal dental caries in digital radiographs was similar when obtained in in vivo and in vitro conditions.
  
  
  METHODS
  Thirty-nine noncavitated teeth were collected from 11 subjects who had part of upper or lower jaws excised owing to cyst or neoplasm. Before operation, radiographs of the teeth involved were taken with the digital imaging system Digora Optime (Soredex, Helsinki, Finland), and after operation, the same extracted teeth were mounted in plaster blocks and exposed with the same digital imaging system. The teeth were subsequently sectioned for histologic validation of the lesions. Six observers evaluated all of the radiographs according to a 5-category scale. Receiver operating characteristic analysis was performed. Repeated-measure analysis of variance was used for the statistical analysis.
  
  
  RESULTS
  There were no significant differences between digital radiographs taken in in vivo and in vitro conditions for diagnosis of proximal dental caries (P = .286).
  
  
  CONCLUSIONS
  Detection accuracy of proximal dental caries obtained from an in vitro study can be considered to be representative of diagnostic accuracy of proximal dental caries obtained in the real clinical situation.
authors.affiliation: Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, Beijing, China. kqgang@bjmu.edu.cn
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Xin-min
authors.initials: XM
authors.lastname: Qu
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Zu-yan
authors.initials: ZY
authors.lastname: Zhang
authors.forename: Xu-chen
authors.initials: XC
authors.lastname: Ma
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003731:Dental Caries / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D019252:Radiography, Dental, Digital / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity