title: [Breast cancer metastasis in distal phalanx of the big toe. Case report].
abstract: Breast cancer represents the most prevalent malignancies in women and bone is the first site of metastasis in 26-50% of cases. Usually metastasis involve limbs in 16%. We present a rare case of 47-year-old woman, who underwent to monolateral mastectomy for lobular cancer. After 8 years from surgery, she presented pain, swelling and functional limitations, gradually increasing, to the left big toe. X-rays and MRI showed a lucent area of bone destruction on the shaft of the distal phalanx of the left big toe. Surgical biopsy on the excised bone assessed for breast cancer metastasis.
authors.affiliation: "Sapienza" Università di Roma, Policlinico Umberto l di Roma, Cattedra Chirurgia Plastica Ricostruttiva ed Estetica.
authors.forename: B
authors.initials: B
authors.lastname: Carlesimo
authors.forename: M
authors.initials: M
authors.lastname: Tempesta
authors.forename: P
authors.initials: P
authors.lastname: Fioramonti
authors.forename: G
authors.initials: G
authors.lastname: Bistoni
authors.forename: M
authors.initials: M
authors.lastname: Ruggiero
authors.forename: F
authors.initials: F
authors.lastname: Marchetti
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018275:Carcinoma, Lobular / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003951:Diagnostic Errors; D004967:Estrogens; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D015409:Mastectomy, Radical; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D010019:Osteomyelitis / Q000175:diagnosis; D011859:Radiography; D013629:Tamoxifen / Q000627:therapeutic use; D050277:Toe Phalanges / Q000473:pathology* / Q000601:surgery
chemical_list: D018931:Antineoplastic Agents, Hormonal; D004967:Estrogens; D013629:Tamoxifen