Comparison of peritoneal carcinomatosis scoring methods in predicting resectability and prognosis in advanced ovarian cancer.
OBJECTIVE
The aim of this study was to compare carcinomatosis scores, and to determine their relevance to predict resectability, morbidity, and outcome.


METHODS
From 2005-2008, 61 patients underwent surgery for ovarian cancer. We compared International Federation Gynecology and Obstetrics (FIGO), peritoneal cancer index, Eisenkop, Aletti, Fagotti, and Fagotti-modified scores.


RESULTS
There was a strong correlation between the different scores. In predicting resectability, Fagotti-modified and peritoneal cancer index outperformed other scores. We demonstrated a strong association between the occurrence of postoperative complications and Aletti, peritoneal cancer index, and Eisenkop scores (P < .0001). For progression-free survival, we observed significant differences among FIGO, peritoneal cancer index, Eisenkop, Fagotti-modified, and Aletti stages (P < .05). For stage III/IV patients, only Aletti score remains significant to predict resectability. This suggests that complete respectability is more related to the surgical effort than to the extent of the disease.


CONCLUSIONS
Alternative ranking systems provide additional information over FIGO for complete resectability, complications, and survival.
Chéreau
Elisabeth
E
Department of Gynecology-Obstetrics and Prediction Unit (INSERM U953, Epidemiological Research Unit on Perinatal and Women's Health), Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, and CancerEst, Université Pierre et Marie Curie, Paris, France.
Ballester
Marcos
M
Selle
Frédéric
F
Cortez
Annie
A
Daraï
Emile
E
Rouzier
Roman
R
D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D010534:Peritoneal Neoplasms / Q000556:secondary*; D011379:Prognosis; D012372:ROC Curve