Antibiotic prescribing for acute respiratory infection and subsequent outpatient and hospital utilization in veterans with spinal cord injury and disorder.
OBJECTIVE
To assess the association between antibiotic prescribing for acute respiratory infection (ARI) and subsequent health-care utilization in veterans with spinal cord injury and disorder (SCI/D).


METHODS
Retrospective cohort of veterans with SCI/D.


METHODS
Veterans Affairs medical facilities that provide outpatient care.


METHODS
Veterans with SCI/D with a diagnosis of acute bronchitis or upper respiratory infection during an outpatient visit between fiscal year 2006 and 2007 that did not result in same-day hospitalization.


METHODS
Receipt of a new antibiotic prescription occurring within 3 days before or after an ARI visit.


METHODS
Subsequent outpatient visit or hospitalization within 30 days of the index ARI visit.


RESULTS
A total of 1277 patients were identified with ARI; 53.2% were prescribed an antibiotic. An outpatient clinic visit within 30 days of the index ARI visit occurred in 47.0% of patients. Receipt of an antibiotic prescription was not associated with a subsequent outpatient visit. However, in those with certain chronic respiratory conditions (cough, shortness of breath, bronchitis not specified as acute or chronic, and allergic rhinitis), those prescribed antibiotics were less likely to return for an outpatient visit than those not prescribed antibiotics (adjusted relative risk =0.77, 95% confidence interval = 0.61-0.97); no association was observed in those patients without these conditions. A total of 7.9% of patients were hospitalized within 30 days and did not differ by prescribing group. The 30-day mortality rate was 0.6%.


CONCLUSIONS
Certain chronic respiratory conditions in veterans with SCI/D may be risk factors for increased health-care utilization and potentially poor outcomes if a patient is not treated with antibiotics for ARI. However, in those without these conditions, those with ARI who were prescribed antibiotics have similar utilization to those not prescribed antibiotics. These data suggest that in the absence of chronic respiratory conditions, antibiotic use for ARI can be curbed in this population that is at high risk for respiratory complications.
Evans
Charlesnika T
CT
Department of Veterans Affairs (VA), Center for Management of Complex Chronic Care, Edward Hines Jr. VA Hospital (151H), Hines, IL, USA. Charlesnika.Evans@va.gov
Li
Keran
K
Burns
Stephen P
SP
Smith
Bridget
B
Lee
Todd A
TA
Weaver
Frances M
FM
D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001991:Bronchitis / Q000188:drug therapy*; D005260:Female; D006296:Health Services / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians'; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012189:Retrospective Studies; D013119:Spinal Cord Injuries / Q000534:rehabilitation; D016896:Treatment Outcome; D014481:United States; D014728:Veterans
D000900:Anti-Bacterial Agents