First efficient synthesis of fluorinated glycidic esters from ketones.
Treatment of various ketones with ethyl dibromofluoroacetate in the presence of diethylzinc and dimethylaminoethanol or triphenylphosphine provides rapid access to corresponding fluorinated glycidic esters. Simplified workup allowed first characterization of these compounds.
Lemonnier
Gérald
G
INSA de Rouen et Université de Rouen, CNRS UMR 6014 COBRA & FR 3038, IRCOF, Mont-Saint-Aignan Cedex, France.
Zoute
Ludivine
L
Quirion
Jean-Charles
JC
Jubault
Philippe
P
D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D004852:Epoxy Compounds; D004952:Esters; D006845:Hydrocarbons, Fluorinated; D007659:Ketones