Long-term follow up of thymus in patients with myasthenia gravis.
We examined transversely the thymus of 33 myasthenia gravis (MG) patients followed up for more than 5 years and found three thymomas. One was found 21 years after thymoma resection (Masaoka I, WHO Type B2 thymoma) and extended thymectomy. The other two were non-thymomatous at onset, and they were not treated with extended thymectomy. Therapeutic guidelines should mention the importance of follow-up in MG thymus.
Sugawara
Masashiro
M
Department of Neurology, Akita University, Graduate School of Medicine, Akita, Japan. masashir@gipc.akita-u.ac.jp
Wada
Chizu
C
Okawa
Satoshi
S
Kobayashi
Michio
M
Abe
Erika
E
Obara
Koji
K
Kamada
Sachiko
S
Ohnishi
Hirohide
H
Toyoshima
Itaru
I
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D011239:Prednisolone / Q000627:therapeutic use; D018709:Statistics, Nonparametric; D016559:Tacrolimus / Q000627:therapeutic use; D013934:Thymectomy; D013945:Thymoma / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D013953:Thymus Neoplasms / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D011239:Prednisolone; D016559:Tacrolimus