GQ1b ganglioside antibody-related disorders: a case with a complex phenotype.
We described an overlap syndrome associating Miller Fisher syndrome (MFS) and acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Furthermore, the patient presented unusual neurological manifestations including headache, T10 sensory level, urinary urgency, and gadolinium enhancement of the spinal roots. One year follow-up was characterized by clinical recovery and persistent high rates of anti-GQ1b, -GD1b and -GT1b antibodies. Our case suggests broad phenotype of persistent antigangliosides antibodies.
Pers
Y M
YM
Department of Neurology, Caremeau Hospital, CHU Nîmes, France.
Taïeb
G
G
Ayrignac
X
X
Castelnovo
G
G
Hubert
A M
AM
Boucraut
J
J
Labauge
P
P
D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005732:Gangliosides / Q000276:immunology*; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D016896:Treatment Outcome
D005732:Gangliosides; D007136:Immunoglobulins; C039129:GQ1b ganglioside