title: Cranial ultrasonography in neonates: role and limitations.
abstract: In experienced hands, cranial ultrasonography (cUS) is an excellent tool to detect the most frequently occurring brain abnormalities in preterm and full-term neonates, to study the evolution of lesions, and to follow brain maturation. It enables screening of the brain and serial imaging in high-risk neonates. However, cUS also has limitations and magnetic resonance imaging is needed in most neonates with (suspected) parenchymal brain injury and/or neurological symptoms and in very preterm infants. In this review, we discuss the applications, possibilities, indications, predictive value, and limitations of neonatal cUS. We will pay attention to the standard cUS procedure and expand on optimizing the possibilities of cUS by using supplemental acoustic windows and changing transducers and focus points. For illustration numerous cUS images are provided.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands. g.van_wezel-meijler@lumc.nl
authors.forename: Gerda
authors.initials: G
authors.lastname: van Wezel-Meijler
authors.forename: Sylke J
authors.initials: SJ
authors.lastname: Steggerda
authors.forename: Lara M
authors.initials: LM
authors.lastname: Leijser
mesh_terms: D001930:Brain Injuries / Q000000981:diagnostic imaging*; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000000981:diagnostic imaging; D007231:Infant, Newborn; D007234:Infant, Premature; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation / Q000379:methods* / Q000592:standards