title: Proteinase-mediated drastic morphological change of peptide-amphiphile to induce supramolecular hydrogelation.
abstract: We report a novel peptide-amphiphile having a simple molecular structure that can gelate an aqueous solution at a remarkably low concentration and can be designed to be responsive to a disease-related enzyme by undergoing a drastic morphological change.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering and Center for Future Chemistry, Kyushu University, 744 Moto-oka, Fukuoka 819-0395, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Koda
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Maruyama
authors.forename: Nami
authors.initials: N
authors.lastname: Minakuchi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Nakashima
authors.forename: Masahiro
authors.initials: M
authors.lastname: Goto
mesh_terms: D000595:Amino Acid Sequence; D020783:Matrix Metalloproteinase 7 / Q000737:chemistry* / Q000378:metabolism; D008823:Micelles; D057139:Nanofibers / Q000737:chemistry; D010168:Palmitates / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014867:Water / Q000737:chemistry
chemical_list: D008823:Micelles; D010168:Palmitates; D010455:Peptides; D014867:Water; D020783:Matrix Metalloproteinase 7