[But...was there ever a Clark classification of melanomas?].
For the past 40 years, the Clark classification of cutaneous melanoma has been accepted and used by the vast majority of dermatologists and pathologists throughout the world. However,after careful rereading of the most relevant articles by Clark and his collaborators, we can affirm that the classification was only ever of passing validity. Today, the possible morphological differences between one case of cutaneous melanoma and another are of no proven prognostic implication. In addition, the morphological differences that can be found are much more closely related to the different localization that to the tumor itself.
Sánchez Yus
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Departamento de Medicina II Dermatología, Facultad de Medicina, Universidad Complutense, Madrid, España. evasyus@hotmail.com
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Simón
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D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000145:classification / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000648:ultrastructure; D008545:Melanoma / Q000145:classification* / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009381:Neoplasms, Radiation-Induced / Q000145:classification / Q000473:pathology; D009928:Organ Specificity; D011379:Prognosis; D012878:Skin Neoplasms / Q000145:classification* / Q000473:pathology