Peroxisome diversity and evolution.
Peroxisomes are organelles bounded by a single membrane that can be found in all major groups of eukaryotes. A single evolutionary origin of this cellular compartment is supported by the presence, in diverse organisms, of a common set of proteins implicated in peroxisome biogenesis and maintenance. Their enzymatic content, however, can vary substantially across species, indicating a high level of evolutionary plasticity. Proteomic analyses have greatly expanded our knowledge on peroxisomes in some model organisms, including plants, mammals and yeasts. However, we still have a limited knowledge about the distribution and functionalities of peroxisomes in the vast majority of groups of microbial eukaryotes. Here, I review recent advances in our understanding of peroxisome diversity and evolution, with a special emphasis on peroxisomes in microbial eukaryotes.
Gabaldón
Toni
T
Centre for Genomic Regulation (CRG), Dr Aiguader, 88 08003 Barcelona, Spain. tgabaldon@crg.es
D000818:Animals; D005075:Biological Evolution; D056890:Eukaryota / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism; D008954:Models, Biological; D020675:Peroxisomes / Q000235:genetics* / Q000378:metabolism* / Q000648:ultrastructure; D010944:Plants / Q000235:genetics / Q000378:metabolism; D021381:Protein Transport; D020543:Proteome; D017382:Reactive Oxygen Species / Q000378:metabolism; D056901:Rhizaria / Q000235:genetics / Q000378:metabolism; D013559:Symbiosis
D005227:Fatty Acids; D020543:Proteome; D017382:Reactive Oxygen Species