title: [Androgenic and estrogenic modulation in the prostate: an approach in rodent experimental models with emphasis on structural biology].
abstract: The endocrine system is a complex network of glands and hormones that regulates many of the body's functions; including growth, development and maturation, as well as the way several organs operate. The prostate is an important target of hormones and its functional maturity and development are influenced by steroids levels. Our research group has been evaluating the potential effects of the steroidal agents on the Mongolian gerbil (Meriones unguiculatus) male and female prostate using different morphological and immunohistochemical methods. Our results have revealed the Mongolian gerbil prostate as an important tool for the morphofunctional studies of steroid hormones and its antagonist actions.
authors.affiliation: Departamento de Biologia, Instituto de Biociências, Letras e Ciências Exatas, Universidade Estadual Paulista, São José do Rio Preto, SP, Brasil. taboga@ibilce.unesp.br
authors.forename: Sebastião Roberto
authors.initials: SR
authors.lastname: Taboga
authors.forename: Patricia Simone Leite
authors.initials: PS
authors.lastname: Vilamaior
authors.forename: Rejane Maira
authors.initials: RM
authors.lastname: Góes
mesh_terms: D000375:Aging / Q000502:physiology; D000728:Androgens / Q000502:physiology*; D000818:Animals; D004967:Estrogens / Q000502:physiology*; D005260:Female; D005849:Gerbillinae; D008297:Male; D023421:Models, Animal; D011467:Prostate / Q000033:anatomy & histology* / Q000187:drug effects / Q000502:physiology*; D012737:Sex Factors
chemical_list: D000728:Androgens; D004967:Estrogens