Pruritus in cutaneous T-cell lymphomas: frequent, often severe and difficult to treat.
Pruritus has a well-known association with Hodgkin's disease and other nodal lymphomas; indeed it often reveals the disease. Pruritus is also an important symptom of cutaneous T-cell lymphomas. Lymphoma-associated itch is thus both frequent and severe, but its pathophysiology remains unclear. Few studies have evaluated the efficacy of therapeutic agents in the management of cutaneous T-cell lymphoma-related pruritus. The main objective of treatment remains disease control. Pruritus management is generally based on the physician's experience. Treatment is very difficult, especially in Sézary syndrome. We present here management strategies for cutaneous lymphoma-associated pruritus.
Meyer
Nicolas
N
Service de Dermatologie, Université Paul Sabatier-Toulouse III et CHU Toulouse, Toulouse, France. meyer.n@chu-toulouse.fr
Paul
Carle
C
Misery
Laurent
L
D000982:Antipruritics / Q000627:therapeutic use*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000628:therapy; D010789:Phototherapy; D011537:Pruritus / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012720:Severity of Illness Index; D012751:Sezary Syndrome / Q000150:complications* / Q000628:therapy; D012878:Skin Neoplasms / Q000150:complications* / Q000628:therapy; D016896:Treatment Outcome
D000982:Antipruritics