title: Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles.
abstract: Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with various aliphatic and aromatic secondary amines are reported for the first time. The reaction gave the corresponding trans-1,2-dihydronaphthalenol derivatives in good yields with moderate enantioselectivities in the presence of 2.5 mol % [Ir(COD)Cl](2) and 5 mol % bisphosphine ligand (S)-p-Tol-BINAP. The trans-configuration of 3f was confirmed by X-ray crystallography.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China. yangdq@scnu.edu.cn
authors.forename: Dingqiao
authors.initials: D
authors.lastname: Yang
authors.forename: Ping
authors.initials: P
authors.lastname: Hu
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Long
authors.forename: Yujuan
authors.initials: Y
authors.lastname: Wu
authors.forename: Heping
authors.initials: H
authors.lastname: Zeng
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Xiongjun
authors.initials: X
authors.lastname: Zuo