title: Flavanone and diphenylpropane glycosides and glycosidic acyl esters from Viscum articulatum.
abstract: Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3''-tetramethoxy-1,3-diphenylpropane)-4''-O-beta-d-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.
authors.affiliation: Division of Herbal Drugs and Natural Products, National Research Institute of Chinese Medicine, Taipei 112, Taiwan, Republic of China. kuoyh@nricm.edu.tw
authors.forename: Yu-Jen
authors.initials: YJ
authors.lastname: Kuo
authors.forename: Yu-Ching
authors.initials: YC
authors.lastname: Yang
authors.forename: Li-Jie
authors.initials: LJ
authors.lastname: Zhang
authors.forename: Ming-Der
authors.initials: MD
authors.lastname: Wu
authors.forename: Li-Ming Yang
authors.initials: LM
authors.lastname: Kuo
authors.forename: Yuh-Chi
authors.initials: YC
authors.lastname: Kuo
authors.forename: Syh-Yuan
authors.initials: SY
authors.lastname: Hwang
authors.forename: Cheng-Jen
authors.initials: CJ
authors.lastname: Chou
authors.forename: Kuo-Hsiung
authors.initials: KH
authors.lastname: Lee
authors.forename: Hsiu-O
authors.initials: HO
authors.lastname: Ho
authors.forename: Yao-Haur
authors.initials: YH
authors.lastname: Kuo
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004952:Esters; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D009417:Nerve Tissue / Q000166:cytology / Q000187:drug effects; D009569:Nitric Oxide / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D010851:Picrates / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D013624:Taiwan; D028181:Viscum / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D004952:Esters; D044950:Flavanones; D006027:Glycosides; D008070:Lipopolysaccharides; D010851:Picrates; D009569:Nitric Oxide; C004931:1,1-diphenyl-2-picrylhydrazyl; C028610:flavanone