So-called sclerosing hemangioma of lung: current concept.
Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features. Despite various patterns, there are 2 unifying cellular components: "surface cells" and "round cells." Although histogenesis has been debated for decades, most ultrastructural, immunocytochemical, and molecular studies strongly indicate a neoplastic epithelial derivation for both cellular components. Herein, we present a review of sclerosing hemangioma and summarize the essential data regarding histologic, cytologic, and ancillary findings of this distinctive pulmonary neoplasm.
Kalhor
Neda
N
Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, USA. nkalhor@mdanderson.org
Staerkel
Gregg A
GA
Moran
Cesar A
CA
D014408:Biomarkers, Tumor / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D047868:Pulmonary Sclerosing Hemangioma / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*
D014408:Biomarkers, Tumor