title: Primary retroperitoneal teratomas in children: a single institution experience.
abstract: OBJECTIVE
  This study aims to highlight the clinical features, investigations and treatment outcome of retroperitoneal teratomas (RPT) in children.
  
  
  METHODS
  A total of eight patients (six males and two females, age range between 6 months-10 years) of RPT admitted in the department of Paediatric Surgery, PGIMS, Rohtak, between 1996-2008, were studied. The patients were investigated with hematology, x-ray, ultrasound, and computerised tomography (CT) of abdomen and serum alpha-fetoprotein levels in pre and postoperative period. All patients underwent complete surgical resection. In one patient, the tumour had malignant component (yolk sac) and was given postoperative chemotherapy. Postoperative follow-up included serum alpha-fetoprotein in addition to clinical examination and radiological assessment to detect recurrences.
  
  
  RESULTS
  The tumours were located on both sides in almost equal proportion (four on right, three on left, and one bilateral]. All tumours could be excised completely preserving the kidneys in all patients. But in one patient injury to inferior vena cava (IVC) occurred which was repaired successfully. Majority (7 out of 8) were histological benign, and in one yolk sac tumour was malignant component which needed chemotherapy. All children were on follow-up and one patient with malignancy lost to follow-up after three cycles of chemotherapy. In rest there was no tumour recurrence.
  
  
  CONCLUSIONS
  RPT are rare paediatric neoplasms. As majority are benign, a complete excision preserving the kidneys, is usually curative. Serum alpha-fetoprotein is a reliable method of assessing recurrence. Malignancy in the tumour may warrant further chemotherapy.
authors.affiliation: Department of Paediatric Surgery, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India.
authors.forename: K N
authors.initials: KN
authors.lastname: Rattan
authors.forename: Y S
authors.initials: YS
authors.lastname: Kadian
authors.forename: V J
authors.initials: VJ
authors.lastname: Nair
authors.forename: V
authors.initials: V
authors.lastname: Kaushal
authors.forename: N
authors.initials: N
authors.lastname: Duhan
authors.forename: S
authors.initials: S
authors.lastname: Aggarwal
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009549:Nigeria; D011860:Radiography, Abdominal; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000601:surgery*; D012189:Retrospective Studies; D013724:Teratoma / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins