Prevalence of non-penicillin-susceptible group B streptococcus in Philadelphia and specificity of penicillin resistance screening methods.
A total of 1,991 group B streptococcus (GBS) isolates, collected in 2008 and 2009, were tested for non-penicillin susceptibility by broth microdilution, disk testing, and oxacillin screening agar. No GBS isolates were non-penicillin susceptible. Oxacillin and ceftizoxime disk testing results showed that proposed screening criteria are nonspecific. The oxacillin screening agar was specific but of unknown sensitivity.
Kasahara
Kei
K
Center for Infectious Diseases, Nara Medical University, Nara, Japan.
Baltus
Andrew J
AJ
Lee
Sun-Hwa
SH
Edelstein
Martha A
MA
Edelstein
Paul H
PH
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015296:Ceftizoxime / Q000494:pharmacology; D006801:Humans; D008403:Mass Screening / Q000379:methods; D008826:Microbial Sensitivity Tests / Q000379:methods; D010068:Oxacillin / Q000494:pharmacology; D010403:Penicillin Resistance; D015143:Philadelphia / Q000453:epidemiology; D015995:Prevalence; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D015296:Ceftizoxime; D010068:Oxacillin