Hypertension in gestational diabetes mellitus: pathophysiology and long-term consequences.
Gestational hypertension and gestational diabetes mellitus are the most frequent obstetric disorders during pregnancy. The rates of both disorders are expected to increase as a result of delayed pregnancy at a later maternal age, the epidemic of obesity and the increased frequency of using assisted reproductive technology in women with infertility. Pregnancies complicated one or both of these disorders are also associated with adverse consequences for the mother and infant (both acute and long-term). The objectives of this review are to describe the association between gestational hypertension and gestational diabetes, and to discuss approaches to management and summarize long-term consequences of gestational hypertension.
Sibai
Baha M
BM
University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. baha.sibai@uc.edu
Ross
Michael G
MG
D016640:Diabetes, Gestational / Q000453:epidemiology / Q000209:etiology* / Q000534:rehabilitation* / Q000628:therapy; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology / Q000209:etiology* / Q000534:rehabilitation* / Q000628:therapy; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000502:physiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D011297:Prenatal Exposure Delayed Effects / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation / Q000628:therapy