Arisandilactone A, a new triterpenoid from the fruits of Schisandra arisanensis.
A phytochemical investigation of the fruits of Schisandra arisanensis has yielded a novel triterpenoid, arisandilactone A (1). Compound 1 has an unprecedented skeleton having a 5/5/7/5/8/5-fused hexacyclic ring system. The structure of 1 was elucidated by spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. A plausible biosynthetic pathway for 1 is also discussed.
Cheng
Yuan-Bin
YB
School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Liao
Tzu-Ching
TC
Lo
I-Wen
IW
Chen
Yu-Chen
YC
Kuo
Yuh-Chi
YC
Chen
Shun-Ying
SY
Chien
Ching-Te
CT
Shen
Ya-Ching
YC
D002845:Chromatography; D005638:Fruit / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D032141:Schisandra / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
D006571:Heterocyclic Compounds; D014315:Triterpenes; C549485:arisandilactone A