Breast cancer in Cowden syndrome: manifestation of a familial cancer syndrome.
Cowden syndrome is a familial cancer predisposition syndrome associated with an increased risk for breast, thyroid, and endometrial cancers and benign manifestations. With early detection and appropriate therapeutic treatment, many of its associated tumors and cancers are treatable. By better understanding mutations such as Cowden syndrome, additional targeted therapies can be developed and delivered.
Erickson
Janetlynne
J
Department of Nursing, University of Michigan-Flint, USA. Janetlye@umflint.edu
Lyon
Debra E
DE
D000328:Adult; D001943:Breast Neoplasms / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006223:Hamartoma Syndrome, Multiple / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008487:Medical History Taking; D014481:United States / Q000453:epidemiology