Nontraditional reactions of azomethine ylides: decarboxylative three-component couplings of alpha-amino acids.
New reactions of azomethine ylides with nontraditional dipolarophiles are reported. Azomethine ylides, formed in situ via decarboxylative condensations of alpha-amino acids with aldehydes, undergo reactions with naphthols, indoles, alkynes, and nitroalkanes.
Zhang
Chen
C
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA.
Seidel
Daniel
D
D000480:Alkynes / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry; D009284:Naphthols / Q000737:chemistry; D013882:Thiosemicarbazones / Q000737:chemistry*
D000480:Alkynes; D000596:Amino Acids; D001391:Azo Compounds; D002264:Carboxylic Acids; D007211:Indoles; D009284:Naphthols; D013882:Thiosemicarbazones; C512188:azomethine