Neurocognitive function of patients with severe combined immunodeficiency.
Hematopoietic stem cell transplantation (HSCT) has offered a curative approach for treating patients with severe combined immunodeficiency (SCID). However, HSCT may have long-term effects on some of these patients. This article reviews the literature regarding long-term neurocognitive function of patients who have received HSCT for SCID, including the effect of disease-specific characteristics, psychosocial factors, being a chronically ill child, and transplant-related factors.
Shah
Ami J
AJ
Division of Research Immunology/Bone Marrow Transplantation, Department of Pediatrics, The Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California Keck School of Medicine, 4650 Sunset Boulevard, MS # 62, Los Angeles, CA 90027, USA. Ashah@chla.usc.edu
Kohn
Donald B
DB
D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology; D016511:Severe Combined Immunodeficiency / Q000150:complications / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D013995:Time