Rh(2)(OAc)(4)-AgOTf cooperative catalysis in cyclization/three-component reactions for concise synthesis of 1,2-dihydroisoquinolines.
Dirhodium acetate and silver triflate cooperatively catalyzed tandem cyclization/three-component reactions of 2-alkynylarylaldimines with diazo compounds and water or alcohols are reported to afford 1,2-dihydroisoquinolines bearing alpha-hydroxyl-beta-amino carboxylate skeleton in high yield.
Guo
Zhenqiu
Z
Department of Chemistry, East China Normal University, Shanghai 200062, People's Republic of China.
Cai
Mei
M
Jiang
Jun
J
Yang
Liping
L
Hu
Wenhao
W