Synthesis of 1-acyl-3-isopropenylbenzimidazolone derivatives and their activity against Botrytis cinerea.
A series of 1-acyl-3-isopropenylbenzimidazolone derivatives were synthesized, and their structures were characterized by (1)H and (13)C NMR and elemental analysis. Their fungicidal activities against Botrytis cinerea were also evaluated by spore germination assay. The acrylic acid, methacrylic acid, 4-chlorophenyl acetic acid, and 2-chlorobenzoic acid derivatives exhibited strong fungicidal activity. This implied that benzimidazolones might be potential fungicide leading compounds.
Li
Sheng-Kun
SK
Institute of Pesticide Science, Northwest Agricultural and Forestry University, Yangling, Shaanxi 712100, China.
Ji
Zhi-Qin
ZQ
Zhang
Ji-Wen
JW
Guo
Zheng-Yan
ZY
Wu
Wen-Jun
WJ
D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D020171:Botrytis / Q000187:drug effects*; D005659:Fungicides, Industrial / Q000138:chemical synthesis* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy
D001562:Benzimidazoles; D005659:Fungicides, Industrial