title: Churg-Strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings.
abstract: OBJECTIVE
  The aim of this study was to compare the high-resolution computed tomographic findings between Churg-Strauss syndrome (CSS) and chronic eosinophilic pneumonia (CEP).
  
  
  METHODS
  We retrospectively reviewed the clinical records of 16 patients with CSS and 34 patients with CEP.
  
  
  RESULTS
  Twelve (35%) of the 34 patients with CEP had a history of asthma. Although the subpleural distribution of ground-glass opacities (GGOs) and consolidation was common both in CSS and CEP, the midzone distribution was more frequent in CSS (44%) than in CEP (12%). Centrilobular nodules within GGOs were significantly more frequent in CSS (56%) than in CEP (18%). In contrast, traction bronchiectasis associated with volume loss was demonstrated more frequently in CEP (74%) than in CSS (25%).
  
  
  CONCLUSIONS
  On high-resolution computed tomography, the presence of the midzone distribution and nodules within GGOs without traction bronchiectasis suggests CSS rather than CEP.
authors.affiliation: Department of Integrated Pulmonology, Tokyo Medical and Dental University, Tokyo, Japan. furuie.pulm@tmd.ac.jp
authors.forename: Masashi
authors.initials: M
authors.lastname: Furuiye
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Yoshimura
authors.forename: Akiko
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Meiyo
authors.initials: M
authors.lastname: Tamaoka
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ohtani
authors.forename: Shuji
authors.initials: S
authors.lastname: Miyake
authors.forename: Naohiko
authors.initials: N
authors.lastname: Inase
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yoshizawa
mesh_terms: D002908:Chronic Disease; D015267:Churg-Strauss Syndrome / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*