title: [Pregnancy and multiple sclerosis].
abstract: Because multiple sclerosis is a disease that affects young women, the question of pregnancy frequently arises early in the management of the disease. Although the relapse rate decreases during the nine months of pregnancy, it rises significantly during the first trimester post-partum, affecting one third of patients. Pregnancy has no influence on disability progression. Patients have no particular difficulties during pregnancy, labor or delivery. No significant fetal risk has been reported. Neither breast-feeding nor epidural analgesia is deleterious. Disease-modifying treatment must be stopped before conception.
authors.affiliation: Service de neurologie, hôpital général, CHU, équipe d'accueil de l'UB n(o) 4184, BP 1519, 21033 Dijon cedex, France. thibault.moreau@chu-dijon.fr
authors.forename: Thibault
authors.initials: T
authors.lastname: Moreau
authors.forename: Sandrine
authors.initials: S
authors.lastname: Brunot
authors.forename: Grégory
authors.initials: G
authors.lastname: Couvreur
authors.forename: Agnès
authors.initials: A
authors.lastname: Fromont
mesh_terms: D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy; D011256:Pregnancy Outcome