Anti-N-methyl-D-aspartate-receptor encephalitis in a four-year-old girl.
Anti-N-methyl-D-aspartate-receptor encephalitis is a recently identified autoimmune disorder. We report on a 4-year-old girl presenting with seizures after nonspecific viral-like symptoms, progressing to severe aphasia, upper limb dyskinesias, fluctuation in consciousness, and inability to walk. Anti-N-methyl-D-aspartate-receptor encephalitis should be included in the differential diagnosis of acute/subacute encephalitis in children.
Biancheri
Roberta
R
Child Neurology and Psychiatry Unit, G. Gaslini Institute and University of Genova, Largo G. Gaslini 5, 16147 Genova, Italy. roberta@biancheri.com
Pessagno
Alice
A
Baglietto
Maria Giuseppina
MG
Irani
Sarosh R
SR
Rossi
Andrea
A
Giribaldi
Gaia
G
Badenier
Marisol Mirabelli
MM
Vincent
Angela
A
Veneselli
Edvige
E
D001037:Aphasia / Q000209:etiology; D020274:Autoimmune Diseases of the Nervous System / Q000175:diagnosis / Q000628:therapy; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology; D004569:Electroencephalography; D004660:Encephalitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*; D012640:Seizures / Q000209:etiology
D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D016194:Receptors, N-Methyl-D-Aspartate