Study on the mechanism of compound mistletoe fluidextract in relieving hypertension.
OBJECTIVE
To observe the effect of fufang jisheng liujin gao (Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD).


METHODS
The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of niuhuang jiangya wan (Bezoar Hypertension-relieving Pills).


RESULTS
Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD.


CONCLUSIONS
The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.
Ye
Fang
F
Qilu Hospital of Shandong University, Jinan 250012, China.
Du
Guang-zhong
GZ
Cui
Ai-qing
AQ
Lu
Xiao-ting
XT
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004195:Disease Models, Animal; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D014784:Mistletoe / Q000737:chemistry*; D051381:Rats; D011918:Rats, Inbred SHR
D004365:Drugs, Chinese Herbal