Psychological impact of isotretinoin treatment in patients with moderate and severe acne.
Acne patients are subject to different degree of psychosocial distress. The emotional impact of acne vulgaris due to disfigurement caused by the disease is undisputed. Most common reactions to the acne are depression and anxiety. The use of isotretinoin, one of the most effective options in acne treatment, increases depression symptoms. The aim of this study was to investigate the psychological status of the patients with moderate to severe acne and to compare patients treated with isotretinoin with patients treated with vitamin C. A total of 85 patients suffering from acne vulgaris were included in the study. The results of this study do not find a significant correlation between the use of isotretinoin and the psychological effects of the drug.
Simić
Dubravka
D
Department for Dermatology and Venerology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina. simicdubravka@gmail.com
Situm
Mirna
M
Letica
Edita
E
Penavić
Jasna Zeljko
JZ
Zivković
Maja Vurnek
MV
Tomić
Teo
T
D000152:Acne Vulgaris / Q000188:drug therapy* / Q000523:psychology*; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control*; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use; D017523:Croatia; D003863:Depression / Q000209:etiology / Q000517:prevention & control*; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies; D012720:Severity of Illness Index
D003879:Dermatologic Agents; D015474:Isotretinoin; D001205:Ascorbic Acid