title: An efficient ultrasonic-assisted synthesis of imidazolium and pyridinium salts based on the Zincke reaction.
abstract: A mild and efficient method has been developed using ultrasound irradiation for the synthesis of imidazolium and pyridinium salts based on the Zincke reaction. Tertiary nitrogen nucleophiles such as pyridines and imidazoles can be alkylated with primary amine by simply using their ammonium form Zincke salts. In almost all cases, a clear yield increase results and a dramatic reduction of the reaction time accompanied by an improved quality of the products occurs.
authors.affiliation: Department of Chemistry, Xinzhou Teachers University, Xinzhou 034000, China. sanhuzhao@yahoo.cn
authors.forename: Sanhu
authors.initials: S
authors.lastname: Zhao
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Xu
authors.forename: Lu
authors.initials: L
authors.lastname: Zheng
authors.forename: Hai
authors.initials: H
authors.lastname: Liu
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007700:Kinetics; D011726:Pyridinium Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D014465:Ultrasonics
chemical_list: D007093:Imidazoles; D011726:Pyridinium Compounds; D012492:Salts; C029899:imidazole