title: Long term survival of primary skeletal muscle lymphoma in a miniature dachshund.
abstract: An 8-year-old miniature dachshund presented with a right femoral muscle mass and anorexia. Cytology of the mass revealed a number of small-sized lymphoid cells containing a pleomorphic-shaped dense nucleus and narrow pale cytoplasm. Histopathology indicated that neoplastic lymphoid cells proliferated in skeletal muscles and replaced the muscular architecture. Immunohistochemical and genetic examinations confirmed the diagnosis of primary skeletal muscle lymphoma classified as the pleomorphic small cell type and T-cell low-grade. Although the dog suffered at least three relapses by combination chemotherapy, the dog survived 713 days after the initial presentation.
authors.affiliation: Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Takeuchi
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Fujino
authors.forename: Yuko
authors.initials: Y
authors.lastname: Goto-Koshino
authors.forename: Koichi
authors.initials: K
authors.lastname: Ohno
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Uchida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayama
authors.forename: Hajime
authors.initials: H
authors.lastname: Tsujimoto
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D001215:Asparaginase / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004285:Dogs; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008558:Melphalan / Q000008:administration & dosage; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D010052:Ovariectomy; D011239:Prednisolone / Q000627:therapeutic use; D017741:Survivors; D014057:Tomography, X-Ray Computed
chemical_list: D003606:Dacarbazine; D011239:Prednisolone; D001215:Asparaginase; D008558:Melphalan