title: Long-term results of gastric bypass surgery in morbidly obese type 1 diabetes patients.
abstract: BACKGROUND
  Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented.
  
  
  METHODS
  Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery.
  
  
  RESULTS
  Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6-0.95 to 0.3-0.83 IU/kg, and absolute reduction in HbA(1c) was 3-4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted.
  
  
  CONCLUSIONS
  RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.
authors.affiliation: Diabetology and Metabolic Diseases Department, Barlicki University Hospital No 1, Kopcinskiego 22, Lodz, Poland. leszek.czupryniak@umed.lodz.pl
authors.forename: Leszek
authors.initials: L
authors.lastname: Czupryniak
authors.forename: Marcin
authors.initials: M
authors.lastname: Wiszniewski
authors.forename: Dariusz
authors.initials: D
authors.lastname: Szymański
authors.forename: Maciej
authors.initials: M
authors.lastname: Pawłowski
authors.forename: Jerzy
authors.initials: J
authors.lastname: Loba
authors.forename: Janusz
authors.initials: J
authors.lastname: Strzelczyk
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications / Q000601:surgery*; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D009767:Obesity, Morbid / Q000097:blood / Q000150:complications / Q000601:surgery*; D055815:Young Adult