Pathologic findings and liver elements in hibernating bats with white-nose syndrome.
Two groups of vespertilionid bats were collected from affected hibernacula. In group 1 (n, 14; pathology and microbiology), the average body weights of all species were at the lower limit of published ranges. Twelve bats (86%) had mycotic growth in the epidermis, hair follicles, and sebaceous glands. Geomyces destructans, with its characteristic curved conidia, was observed microscopically, cultured, and confirmed by polymerase chain reaction. Dermatitis and mural folliculitis was nil to mild. When focally coinfected with Gram-negative bacteria, there was necrosis and pustules. Fat stores were little to abundant in 12 bats (86%) and nil in 2. Thirteen bats (93%) had pulmonary congestion and 7 (50%) had bone marrow granulocytosis. In group 2 (n, 24; liver elements), 3 bats (13%) had potentially toxic lead levels and 1 (4%), potentially toxic arsenic level. There was no evidence of major organ failure or consistent element toxicity.
Courtin
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Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA. francois.courtin@yahoo.fr
Stone
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Risatti
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Gilbert
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Van Kruiningen
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HJ
D000818:Animals; D001151:Arsenic / Q000378:metabolism; D001203:Ascomycota / Q000235:genetics / Q000302:isolation & purification; D002685:Chiroptera / Q000382:microbiology*; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D003881:Dermatomycoses / Q000378:metabolism / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D007854:Lead / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008297:Male; D016133:Polymerase Chain Reaction; D012335:RNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D011897:Random Allocation
D004271:DNA, Fungal; D012335:RNA, Ribosomal; C065096:RNA, ribosomal, 26S; D007854:Lead; D001151:Arsenic