title: Lateral semicircular canal plugging in severe Ménière's disease: a clinical prospective study about 28 patients.
abstract: OBJECTIVE
  To evaluate the safety and efficiency of the plugging of the lateral semicircular canal to control vertigo in severe Ménière's disease (MD).
  
  
  METHODS
  Prospective follow-up study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Twenty-eight patients with MD with refractory vertigo and severe disability (functional scale 5 or 6).
  
  
  METHODS
  Lateral canal plugging was performed in pathological ear for each patient.
  
  
  METHODS
  The evaluation of therapy followed the guidelines for diagnosis and evaluation of therapy in MD (1995). Hearing, frequency of vertigo, and functional disability were assessed in the early follow-up (6 mo) for all the patients and in the late follow-up (2 yr) for 16 patients. In addition, the canal paresis was evaluated by caloric test.
  
  
  RESULTS
  No vital complication occurred. The hearing was preserved in 82% of cases. Lateral canal plugging induced in all cases a canal paresis that was persistent after 2 years. After 2 years (n = 16), the control of vertigo was complete or substantial in 75% of cases (A1, restoration of a normal life: 62.5%; B2, no functional restriction: 12.5%).
  
  
  CONCLUSIONS
  Lateral canal plugging is a safe procedure that induces a canal paresis and allows a good control of vertigo. In view of these results, the lateral canal plugging should be a therapeutic option for controlling rotatory vertigo in severe MD.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Strasbourg, Strasbourg Cedex, France. anne.charpiot@chru-strasbourg.fr
authors.forename: Anne
authors.initials: A
authors.lastname: Charpiot
authors.forename: Dominique
authors.initials: D
authors.lastname: Rohmer
authors.forename: André
authors.initials: A
authors.lastname: Gentine
mesh_terms: D000328:Adult; D000368:Aged; D002150:Caloric Tests; D003051:Cochlea / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006309:Hearing / Q000502:physiology; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000601:surgery*; D008875:Middle Aged; D011446:Prospective Studies; D012665:Semicircular Canals / Q000601:surgery*; D016896:Treatment Outcome; D014717:Vertigo / Q000209:etiology / Q000628:therapy; D014724:Vestibular Function Tests; D055815:Young Adult