title: Angiosarcoma of the breast with silicone granuloma: a case report.
abstract: Angiosarcoma of the breast is a rare non-epithelial tumor and that accounts for less than 0.1% of primary malignancies of the breast. The disease has a relatively higher occurrence among young people, and its prognosis (3-year-survival of only 38%) is extremely poor compared to breast cancer. Here we present a case of an 87-year-old woman who had undergone bilateral breast augmentation with silicone injections in her youth. Although she became aware of a tumor in her right breast, she waited 8 years before seeking treatment. She felt the tumor growing and experienced swelling and pain, but she ended up declining therapy at that time. Two years later she was brought to our hospital by ambulance for continuous bleeding from the same tumor of the breast, which by that time was over 11 cm in diameter. We performed emergency mastectomy. The histological diagnosis was angiosarcoma of the breast with silicone granuloma.
authors.affiliation: Department of Surgery, Social Insurance Kurume Daiichi Hospital, Kurume, Japan. takenaka_miki@kurume-u.ac.jp
authors.forename: Miki
authors.initials: M
authors.lastname: Takenaka
authors.forename: Maki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Isobe
authors.forename: Rin
authors.initials: R
authors.lastname: Yamaguchi
authors.forename: Masamichi
authors.initials: M
authors.lastname: Kojiro
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019928:Breast Implantation / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000209:etiology; D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D020034:Silicone Gels / Q000009:adverse effects*
chemical_list: D020034:Silicone Gels