Solvent free, microwave assisted conversion of aldehydes into nitriles and oximes in the presence of NH2OH x HCl and TiO2.
Aromatic aldehydes bearing electron-donating groups are easily converted into their respective nitriles using NH(2)OH.HCl and TiO(2) under microwave irradiation, while those bearing an electron-withdrawing group give the corresponding oximes.
Hoelz
Lucas Villas-Boas
LV
Departamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, CT Bloco A, Cidade Universitária, Rio de Janeiro, RJ 21941-909, RJ, Brazil.
Gonçalves
Biank Tomaz
BT
Barros
José Celestino
JC
da Silva
Joaquim Fernando Mendes
JF
D000447:Aldehydes / Q000737:chemistry*; D064753:Ammonium Hydroxide; D001547:Benzaldehydes / Q000737:chemistry; D002849:Chromatography, Gas; D006851:Hydrochloric Acid / Q000737:chemistry*; D006878:Hydroxides / Q000737:chemistry*; D013058:Mass Spectrometry; D008872:Microwaves; D009570:Nitriles / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013997:Time Factors; D014025:Titanium / Q000737:chemistry*
D000447:Aldehydes; D001547:Benzaldehydes; D006878:Hydroxides; D009570:Nitriles; D010091:Oximes; D012997:Solvents; C009495:titanium dioxide; D064753:Ammonium Hydroxide; C100058:vanillin; D014025:Titanium; D006851:Hydrochloric Acid