[Detection of human papillomavirus in esophageal carcinoma tissues from Baoding City of Hebei Province].
OBJECTIVE
To investigate the relationship between the human papillomavirus (HPV) and esophageal carcinoma in Baoding City of Hebei Province.


METHODS
We detected HPV DNA in 42 formalin-fixed and paraffin-embedded tissues from surgically resected esophageal carcinomas from Baoding City of Hebei Province, by PCR with the general primer set of GP5 + /6 + for HPV L1 gene and type-specific primer sets for HPV16 and 18 as well.


RESULTS
37 from 42 esophageal carcinoma samples were HPV positive and the rate was 88.1%. Among the samples detected, 19 were HPV16 E6 positive and rate was 45.2%, eight were HPV18 E6 positive and rate was 19.0%.


CONCLUSIONS
The high rate of HPV in the esophageal carcinoma samples suggested that HPV plays an etiologic role in the development of esophageal cancer in Baoding City of Hebei Province.
Zhao
Xiao-yu
XY
College of Life Sciences, Hebei University, Baoding 071002, China.
Li
Shu-ying
SY
Li
Ying
Y
Wang
Xiao-li
XL
Li
Yu-lan
YL
Wu
Xiao-zhou
XZ
Zhou
Ling
L
Liu
Hong-tu
HT
Zeng
Yi
Y
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000821:virology*; D002681:China; D004938:Esophageal Neoplasms / Q000821:virology*; D005260:Female; D052162:Human papillomavirus 16 / Q000235:genetics / Q000302:isolation & purification*; D052161:Human papillomavirus 18 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000821:virology*