Relationship between periodontitis and rheumatoid arthritis and the effect of non-surgical periodontal treatment.
This study analyzed the association of periodontal disease (PD) and rheumatoid arthritis (RA). Seventy-five 35-60-year-old patients were assigned to 5 groups according to the presence (+) or not (-) of PD and RA and the treatment received (TR+) or not (TR-) for PD. Group 3 uses total prosthesis (TP). Clinical and laboratory evaluations were performed at baseline, 3 and 6 months of follow-up by probing pocket depth, bleeding on probing and plaque index for PD, HAQ, DAS28, SF-36 and laboratory: AAG, ESR, CRP for RA. Statistically significant differences for PD after 3 (p=0.0055) and after 6 months (p=0.0066) were obtained in Group 1 (RA+PD+TR+) and 2(RA+PD+TR-); significant reduction in the % of BOP after 6 months (p=0.0128) and significant reduction in the % of Pl after 3 (p=0.0128) and 6 months (p=0.0002) in Group 1. Statistically significant differences between Groups 1 and 3 (RA+TP) for DAS28 at baseline and after 3 months were observed, but not after 6 months. No other parameters for RA were significantly affected. The relationship between RA and PD disease activities is not clear, but the importance of periodontal treatment in the control of inflammation to avoid tooth extraction is evident.
Pinho
Márcia de Noronha
Mde N
Dental School of Campinas, Pontifical Catholic University, Campinas, SP, Brazil. mpinho@sigmanet.com.br
Oliveira
Renê Donizeti Ribeiro
RD
Novaes
Arthur Belém
AB
Voltarelli
Júlio César
JC
D000328:Adult; D000704:Analysis of Variance; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D055113:Chronic Periodontitis / Q000150:complications* / Q000628:therapy*; D012534:Dental Scaling; D003824:Denture, Complete; D006801:Humans; D008875:Middle Aged; D009961:Orosomucoid / Q000032:analysis; D010512:Periodontal Index; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires
D009961:Orosomucoid; D002097:C-Reactive Protein