title: [Bilateral testicular tumors caused by congenital adrenal rest hyperplasia].
abstract: OBJECTIVE
  Testicular tumors are a rare condition associated with congenital adrenal hyperplasia (CAH), originated from intratesticular adrenal rest tumors, and they are rarely associated with malignant tumors. Their histological differentiation from Leydig-cell tumors is quite difficult, which would lead to inappropriate orchiectomies. Thus the objective of this report was to present this diagnostic dilemma.
  
  
  METHODS
  Reported the case of 16-yr-old boy with previous diagnosis of CAH with bilateral testicular enlargement who was recommended to be submitted to a bilateral orchiectomy.
  
  
  RESULTS
  Considering this findings, it was decided to treat conventionally with prednisone with significant reduction of testicular volume, and normalization of androgens levels.
  
  
  CONCLUSIONS
  This case shows the importance of intratesticular adrenal rest tumors in the differential diagnosis of testicular tumors. Cautious approach during investigation and treatment are recommended to avoid inappropriate orchiectomies.
authors.affiliation: Serviço de Endocrinologia e Diabetes, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
authors.forename: Virginia Oliveira
authors.initials: VO
authors.lastname: Fernandes
authors.forename: Antonio Iran Souza
authors.initials: AI
authors.lastname: Barros
authors.forename: Ana Rosa Pinto
authors.initials: AR
authors.lastname: Quidute
authors.forename: Ana Paula Dias Rangel
authors.initials: AP
authors.lastname: Montenegro
authors.forename: Eveline Gadelha Pereira
authors.initials: EG
authors.lastname: Fontenele
authors.forename: Ana Paula Abreu Martins
authors.initials: AP
authors.lastname: Sales
authors.forename: Renan Magalhães
authors.initials: RM
authors.lastname: Montenegro
authors.forename: Francisco Valdeci de Almeida
authors.initials: FV
authors.lastname: Ferreira
authors.forename: Renan Magalhães
authors.initials: RM
authors.lastname: Montenegro
mesh_terms: D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000473:pathology*; D000314:Adrenal Rest Tumor / Q000473:pathology*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007984:Leydig Cell Tumor / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D011241:Prednisone