Tandem Ir-catalyzed allylic substitution reaction of allyl sulfinates and isomerization.
An efficient method for the synthesis of trisubstituted vinyl sulfones is reported. Using the [Ir(COD)Cl](2)/phosphoramidite ligand (L1)/DBU, trisubstituted vinyl sulfones could be synthesized from allyl sulfinates in high yields as exclusively E isomers.
Xu
Qing-Long
QL
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
Dai
Li-Xin
LX
You
Shu-Li
SL
D000498:Allyl Compounds / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000498:Allyl Compounds; D013450:Sulfones; D014753:Vinyl Compounds; D007495:Iridium; C009873:divinyl sulfone