Dexmedetomidine in the neurointensive care unit.
Dexmedetomidine is a new alpha-2 agonist with high specificity to alpha-2 receptors. The aim of this review is to present the most recent topics regarding the advantages in using dexmedetomidine in clinical anesthesia and intensive care, while discussing the controversial issue of its harmful effect on cerebral blood flow.
Farag
Ehab
E
Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio 44195, USA. farage@ccf.org
D000316:Adrenergic alpha-Agonists / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D000758:Anesthesia / Q000379:methods; D002560:Cerebrovascular Circulation / Q000187:drug effects; D003422:Critical Care; D020927:Dexmedetomidine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans
D000316:Adrenergic alpha-Agonists; D020927:Dexmedetomidine