title: Undifferentiated sarcoma of the thyroid in a child.
abstract: The most common malignant tumor of the thyroid is papillary carcinoma. Sarcoma of the thyroid is encountered very rarely; its therapy is complex and poses significant problems due to the problematic location of the tumor. A 14-year-old female was diagnosed with undifferentiated sarcoma of the thyroid and received combined therapy comprising surgery, chemo- and radiotherapy without significant side effects. This case underlines the fact that undifferentiated thyroid sarcoma may be a diagnostic possibility in children with malignant masses of the neck and may be successfully treated with modern therapeutic strategies.
authors.affiliation: Department of Pediatric Hematology-Oncology, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel. s_postovsky@rambam.health.gov.il
authors.forename: Sergey
authors.initials: S
authors.lastname: Postovsky
authors.forename: Eugene
authors.initials: E
authors.lastname: Vlodavsky
authors.forename: Abraham
authors.initials: A
authors.lastname: Kuten
authors.forename: Yaakov
authors.initials: Y
authors.lastname: Shendler
authors.forename: Ilana
authors.initials: I
authors.lastname: Doweck
authors.forename: Myriam Weyl
authors.initials: MW
authors.lastname: Ben Arush
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003609:Dactinomycin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007150:Immunohistochemistry; D011878:Radiotherapy; D012509:Sarcoma / Q000473:pathology* / Q000628:therapy*; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy*; D013965:Thyroidectomy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D004317:Doxorubicin; D007069:Ifosfamide