title: [Prevention of complications in twin gestations and pregnancies after assisted reproduction].
abstract: BACKGROUND
  Twin pregnancies and gestations after assisted reproductive therapy (ART) are of special obstetric significance with regard to their associated risks. However, little is known about preventive approaches specifically evaluated for these constellations.
  
  
  METHODS
  A selective literature search was conducted to examine possible preventive approaches for complications such as hypertensive disorders, anaemia, gestational diabetes, prematurity, and others, seen significantly more often in twin gestations and pregnancies after ART.
  
  
  RESULTS
  For both constellations, preventive approaches are not specifically evaluated for the majority of complications. For some preventive methods a possible detrimental effect cannot even be ruled out.
  
  
  CONCLUSIONS
  The knowledge about specific preventive approaches against complications in twin pregnancies and gestations after ART is scarce. More prospective trials are urgently needed to assess the risks and benefits of prophylactic approaches for these risk constellations.
authors.affiliation: Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Germany. doerte.luedders@uk-sh.de
authors.forename: D W
authors.initials: DW
authors.lastname: Luedders
authors.forename: A
authors.initials: A
authors.lastname: Hornemann
authors.forename: B
authors.initials: B
authors.lastname: Fritzsching
authors.forename: M
authors.initials: M
authors.lastname: Thill
authors.forename: D A
authors.initials: DA
authors.lastname: Beyer
authors.forename: K
authors.initials: K
authors.lastname: Diedrich
authors.forename: M K
authors.initials: MK
authors.lastname: Bohlmann
mesh_terms: D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D015997:Neonatal Screening; D007744:Obstetric Labor Complications / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D011296:Prenatal Diagnosis; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D012308:Risk Management; D014427:Twins