title: Pneumocystis carinii and Pneumocystis wakefieldiae in wild Rattus norvegicus trapped in Thailand.
abstract: This work reports for the first time the presence of two Pneumocystis species in wild Rattus norvegicus specimens from Thailand. Pneumocystis DNA was detected in 57.7% (15/26) wild rats without apparent association with typical pneumocystosis. Pneumocystis carinii was found alone in five rats (19.2%), Pneumocystis wakefieldiae was detected alone in six rats (23.1%), and two rats were infected by both species (7.7%). In addition, a new P. wakefieldiae variant sequence has been identified in three wild R. norvegicus specimens caught in the same geographical area. The high frequency of Pneumocystis in wild rats documented in this study and the apparent scarcity of severe pneumocystosis were consistent with an efficient circulation of rat Pneumocystis species in ecosystems.
authors.affiliation: EA3609-Laboratoire de Parasitologie-Mycologie, Faculté de Pharmacie de Lille, Université Lille Nord-de-France, 59006 Lille, France. magali.chabe@univ-lille2.fr
authors.forename: Magali
authors.initials: M
authors.lastname: Chabé
authors.forename: Vincent
authors.initials: V
authors.lastname: Herbreteau
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Hugot
authors.forename: Noemi
authors.initials: N
authors.lastname: Bouzard
authors.forename: Lucie
authors.initials: L
authors.lastname: Deruyter
authors.forename: Serge
authors.initials: S
authors.lastname: Morand
authors.forename: Eduardo
authors.initials: E
authors.lastname: Dei-Cas
mesh_terms: D000818:Animals; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D011010:Pneumocystis / Q000145:classification* / Q000302:isolation & purification*; D016720:Pneumocystis Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D015995:Prevalence; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology* / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D013785:Thailand / Q000453:epidemiology
chemical_list: D004271:DNA, Fungal; D004275:DNA, Ribosomal