title: Air pollution positively correlates with daily stroke admission and in hospital mortality: a study in the urban area of Como, Italy.
abstract: Some current evidences suggest that stroke incidence and mortality may be higher in elevated air pollution areas. Our study examined the hypothesis of a correlation between air pollution level and ischemic stroke admission and in Hospital mortality in an urban population. Data on a total of 759 stroke admissions and 180 deaths have been obtained over a 4-year period (2000-2003). Five air ambient particles have been studied. A general additive model estimating Poisson distribution has been used, adding meteorological variables as covariates. NO(2) and PM(10) were significantly associated with admission and mortality (P value < 0.05) and with estimated RR of 1.039 (95% CI 1.066-1.013) and 1.078 (95% CI 1.104-1.052) for hospital admission at 2- and 4-day lags, respectively. In conclusion, this study suggests an association between short-term outdoor air pollution exposure and ischemic stroke admission and mortality.
authors.affiliation: Neurology Department, Sant'Anna Hospital, Como, Italy. simone.vidale@hsacomo.org
authors.forename: Simone
authors.initials: S
authors.lastname: Vidale
authors.forename: A
authors.initials: A
authors.lastname: Bonanomi
authors.forename: M
authors.initials: M
authors.lastname: Guidotti
authors.forename: M
authors.initials: M
authors.lastname: Arnaboldi
authors.forename: R
authors.initials: R
authors.lastname: Sterzi
mesh_terms: D000368:Aged; D000397:Air Pollution; D002545:Brain Ischemia / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D015233:Models, Statistical; D009585:Nitrogen Dioxide / Q000032:analysis; D052638:Particulate Matter / Q000032:analysis; D016012:Poisson Distribution; D020521:Stroke / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D013997:Time Factors; D014505:Urban Population
chemical_list: D052638:Particulate Matter; D009585:Nitrogen Dioxide