Two cases of daptomycin-induced eosinophilic pneumonia and chronic pneumonitis.
We present 2 elderly patients who developed lung infiltrates associated with eosinophilia during intravenous daptomycin treatment. Both patients improved quickly after daptomycin was stopped and steroid treatment was initiated. However, complete recovery did not occur, and both patients became chronically steroid dependent.
Lal
Yasir
Y
Sanford School of Medicine of the University of South Dakota, Sioux Falls, 57105, USA. ylal@usd.edu
Assimacopoulos
Aristides P
AP
D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D017576:Daptomycin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000139:chemically induced*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced*; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome; D028761:Withholding Treatment
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D013256:Steroids; D017576:Daptomycin