A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system.
Considerable confusion exists about the correct structural representation of phytoprostanes (PhytoP). Improper use of the different nomenclature systems leads to incorrect structure assignment of PhytoP, which results in wrong synthetic approaches to these molecules and may lead to wrong rationalization of biological activity. A new prostane ring system was found, which is proposed to be termed L(1)-PhytoP or L(2)-IsoP, respectively.
Jahn
Ullrich
U
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo namesti 2, 16610 Prague, Czech Republic. jahn@uochb.cas.cz
Galano
Jean-Marie
JM
Durand
Thierry
T
D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000145:classification*; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry; D013329:Structure-Activity Relationship
D005231:Fatty Acids, Unsaturated