title: [Risk factors of bilateralization of breast cancer: description of five cases in Libreville (Gabon) and review of the literature].
abstract: Approximately 10% of patients diagnosed with breast cancer will develop cancer in the contralateral breast within 10 years. The risk factors for bilateralization are now better understood thanks to advances in molecular biology. Based on reports in the literature the main risk factors are presence of brca 1 or 2 gene mutations and family history. Despite the increasing incidence of breast cancer, this special aspect of the disease remains poorly studied in Gabon as well as in Black Africa in general. Incidence is increasing. This report describes 5 patients and discusses their profiles in relation to the literature. This study provides on update on current knowledge.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital d'Instruction des Armées Omar Bongo Ondimba, Libreville, Gabon. smayi3@yahoo.fr
authors.forename: S
authors.initials: S
authors.lastname: Mayi-Tsonga
authors.forename: H
authors.initials: H
authors.lastname: Kamga
authors.forename: J F
authors.initials: JF
authors.lastname: Meye
authors.forename: E
authors.initials: E
authors.lastname: Belembaogo
mesh_terms: D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D002277:Carcinoma / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D005260:Female; D005681:Gabon; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D010298:Parity; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors