title: [Clinical and functional changes in the biliary tract in patients with psoriasis concurrent with chronic opisthorchiasis].
abstract: OBJECTIVE
  to study the clinical and functional changes in the biliary tract in patents with psoriasis concurrent with chronic opisthorchiasis (CO).
  
  
  METHODS
  60 patients with psoriasis concurrent with CO, 45 patients with psoriasis without helminthism, 30 with CO, and 15 healthy individuals were examined. Chromatic fractional duodenal intubation, dynamic hepatobiliscintigraphy, and ultrasound study of the liver and gallbladder were used. The concentrations of cholesterol, bile acids, bilirubin, total lipids and phospholipids in bile were measured. A number of relative indices, such as cholate-cholesterol coefficient (CCC), Thomas-Hofmann index, and Rubens index were calculated.
  
  
  CONCLUSIONS
  The patients with psoriasis with CO were found to have signs of mainly hypermotor dyskinesia of the biliary tract, as well as increased bile lithogenicity (lower CCC, and increases in the Rubens index and Thomas-Hofmann index).
  
  
  CONCLUSIONS
  The clinical and functional changes found in the biliary tract of the patients with psoriasis concurrent with CO show it necessary to perform antihelminthic therapy in this group of patients.
authors.forename: S A
authors.initials: SA
authors.lastname: Khardikova
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Kuranova
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
authors.forename: M I
authors.initials: MI
authors.lastname: Kaliuzhina
mesh_terms: D000328:Adult; D000818:Animals; D001646:Bile / Q000737:chemistry; D001659:Biliary Tract / Q000469:parasitology / Q000503:physiopathology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D009889:Opisthorchiasis / Q000150:complications* / Q000503:physiopathology*; D009891:Opisthorchis; D011565:Psoriasis / Q000150:complications*