title: Binding bacteria to highly branched poly(N-isopropyl acrylamide) modified with vancomycin induces the coil-to-globule transition.
abstract: Binding of highly branched poly(N-isopropylacrylamide) with vancomycin end groups to Staphylococcus aureus induced a coil-to-globule phase transition. The polymers aggregated this gram-positive bacteria (but not gram-negative bacteria) over a wide range of temperatures, but cooling to 24-26 degrees C progressed the polymer-bound bacteria through a globule-to-coil phase transition, after which the bacteria were released.
authors.affiliation: School of Clinical Dentistry, University of Sheffield, Sheffield S10 2TA, UK.
authors.forename: Joanna
authors.initials: J
authors.lastname: Shepherd
authors.forename: Prodip
authors.initials: P
authors.lastname: Sarker
authors.forename: Kathryn
authors.initials: K
authors.lastname: Swindells
authors.forename: Ian
authors.initials: I
authors.lastname: Douglas
authors.forename: Sheila
authors.initials: S
authors.lastname: MacNeil
authors.forename: Linda
authors.initials: L
authors.lastname: Swanson
authors.forename: Stephen
authors.initials: S
authors.lastname: Rimmer
mesh_terms: D000178:Acrylamides / Q000737:chemistry* / Q000378:metabolism*; D000180:Acrylic Resins; D001419:Bacteria / Q000378:metabolism*; D011108:Polymers / Q000737:chemistry* / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013696:Temperature; D014640:Vancomycin / Q000737:chemistry*
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D011108:Polymers; C052970:poly-N-isopropylacrylamide; D014640:Vancomycin