title: Genotypic shift of porcine circovirus type 2 from PCV-2a to PCV-2b in Spain from 1985 to 2008.
abstract: Changes in porcine circovirus type 2 (PCV-2) genotypes were evaluated before, during and after outbreaks of post-weaning multisystemic wasting syndrome (PMWS) in (1) a retrospective study using pig sera collected in Spain from 1985 to 2008 and (2) a longitudinal study using pig sera collected from two farms in Spain over periods of 7 and 14 years. In both studies, there was a rapid genotypic shift from PCV-2a to PCV-2b that was related to the peak of PMWS epizootics in Spain and the appearance of PMWS on the two farms studied longitudinally.
authors.affiliation: Centre de Recerca en Sanitat Animal, Universitat Autònoma de Barcelona, Edifici CReSA, Campus Bellaterra, Cerdanyola del Vallès, Barcelona 08193, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Cortey
authors.forename: E
authors.initials: E
authors.lastname: Pileri
authors.forename: M
authors.initials: M
authors.lastname: Sibila
authors.forename: J
authors.initials: J
authors.lastname: Pujols
authors.forename: M
authors.initials: M
authors.lastname: Balasch
authors.forename: J
authors.initials: J
authors.lastname: Plana
authors.forename: J
authors.initials: J
authors.lastname: Segalés
mesh_terms: D000818:Animals; D017925:Circovirus / Q000145:classification / Q000235:genetics*; D004196:Disease Outbreaks / Q000662:veterinary; D005260:Female; D005838:Genotype; D008137:Longitudinal Studies; D008297:Male; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000662:veterinary; D053570:Porcine Postweaning Multisystemic Wasting Syndrome / Q000097:blood / Q000453:epidemiology* / Q000821:virology*; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D013552:Swine