title: Diffuse fibromuscular dysplasia successfully treated with scoring balloon angioplasty in a 3-year-old boy.
abstract: In children, up to 10% of the cases of arterial hypertension may be caused by a renovascular disease. The etiology of this renovascular disease is most of the time due to a fibromuscular dysplasia (FMD), which causes a noninflammatory intimal-medial fibroplasia leading to luminal compromise. Percutaneous transluminal angioplasty of FMD is a worldwide-accepted treatment modality for this serious arterial disease with, so far, good safety and long-term efficacy data. Once FMD involves several arterial compartments leading to symptoms the outcomes are poor. Herein we report the case of a 3(1/2)-year-old boy with severe arterial hypertension and abdominal angina due to a diffuse multivisceral FMD involvement, successfully managed by a percutaneous angioplasty approach using a new balloon catheter for plaque modulation.
authors.affiliation: Angiology Division, Heart-Center Bad Krozingen, Südring 15, 79189 Bad Krozingen, Germany. robert.bonvini@hcuge.ch
authors.forename: Robert F
authors.initials: RF
authors.lastname: Bonvini
authors.forename: Aljoscha
authors.initials: A
authors.lastname: Rastan
authors.forename: Sebastian
authors.initials: S
authors.lastname: Sixt
authors.forename: Marc
authors.initials: M
authors.lastname: Righini
authors.forename: Roland
authors.initials: R
authors.lastname: Hofstetter
authors.forename: Thomas
authors.initials: T
authors.lastname: Zeller
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000800:Angioplasty, Balloon / Q000295:instrumentation; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002675:Child, Preschool; D004867:Equipment Design; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D006978:Hypertension, Renovascular / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D008297:Male; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging; D011859:Radiography; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D013157:Splenic Artery / Q000000981:diagnostic imaging; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents