title: A single active trehalose-6-P synthase (TPS) and a family of putative regulatory TPS-like proteins in Arabidopsis.
abstract: Higher plants typically do not produce trehalose in large amounts, but their genome sequences reveal large families of putative trehalose metabolism enzymes. An important regulatory role in plant growth and development is also emerging for the metabolic intermediate trehalose-6-P (T6P). Here, we present an update on Arabidopsis trehalose metabolism and a resource for further detailed analyses. In addition, we provide evidence that Arabidopsis encodes a single trehalose-6-P synthase (TPS) next to a family of catalytically inactive TPS-like proteins that might fulfill specific regulatory functions in actively growing tissues.
authors.affiliation: Laboratory of Functional Biology, Plant Metabolic Signaling Group, Institute of Botany and Microbiology, KU Leuven, Kasteelpark Arenberg 31-bus 2438, B-3001 Heverlee, Belgium.
authors.forename: Lies
authors.initials: L
authors.lastname: Vandesteene
authors.forename: Matthew
authors.initials: M
authors.lastname: Ramon
authors.forename: Katrien
authors.initials: K
authors.lastname: Le Roy
authors.forename: Patrick
authors.initials: P
authors.lastname: Van Dijck
authors.forename: Filip
authors.initials: F
authors.lastname: Rolland
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015153:Blotting, Western; D005964:Glucosyltransferases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017386:Sequence Homology, Amino Acid; D014199:Trehalose / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D014199:Trehalose; D005964:Glucosyltransferases; C099692:trehalose synthase