title: A unique isolate of beak and feather disease virus isolated from budgerigars (Melopsittacus undulatus) in South Africa.
abstract: Beak and feather disease virus (BFDV), the causative agent of psittacine beak and feather disease (PBFD) infects psittaciformes worldwide. We provide an annotated sequence record of three full-length unique genomes of BFDV isolates from budgerigars (Melopsittacus undulatus) from a breeding farm in South Africa. The isolates share >99% nucleotide sequence identity with each other and approximately 96% nucleotide sequence identity to two recent isolates (Melopsittacus undulatus) from Thailand but only between 91.6 and 86.6% identity with all other full-length BFDV sequences. Maximum-likelihood analysis and recombination analysis suggest that the South African budgerigar BFDV isolates are unique to budgerigars, are non-recombinant in origin, and represent a new genotype of BFDV.
authors.affiliation: Electron Microscope Unit, University of Cape Town, Rondebosch, Cape Town, South Africa.
authors.forename: Arvind
authors.initials: A
authors.lastname: Varsani
authors.forename: Gillian K
authors.initials: GK
authors.lastname: de Villiers
authors.forename: Guy L
authors.initials: GL
authors.lastname: Regnard
authors.forename: Robert R
authors.initials: RR
authors.lastname: Bragg
authors.forename: Kulsum
authors.initials: K
authors.lastname: Kondiah
authors.forename: Inga I
authors.initials: II
authors.lastname: Hitzeroth
authors.forename: Edward P
authors.initials: EP
authors.lastname: Rybicki
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000821:virology*; D018173:Circoviridae Infections / Q000662:veterinary* / Q000821:virology; D017925:Circovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D016000:Cluster Analysis; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics*; D016679:Genome, Viral; D005838:Genotype; D046408:Melopsittacus / Q000821:virology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D013019:South Africa
chemical_list: D004279:DNA, Viral