Advantageous use of tBu2P-N=P(iBuNCH2CH2)3N in the Hiyama coupling of aryl bromides and chlorides.
An efficient catalytic route to biaryls by employing (generally) only 0.25 mol % of Pd(OAc)(2) and 0.5 mol % of 1 in the Hiyama coupling reaction is reported. High yields for electron-rich, -neutral, and -deficient aryl chlorides are obtained. A variety of phenylsiloxanes undergo coupling with aryl bromides and chlorides with low Pd(OAc)(2)/1 loadings.
Raders
Steven M
SM
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Kingston
Jesudoss V
JV
Verkade
John G
JG