New cucurbitane-type triterpenoids from Bryonia aspera.
Phytochemical investigation of the chloroform extract of BRYONIA ASPERA roots resulted in the isolation and structure elucidation of two new cucurbitacins (1, 2) together with eight known cucurbitane derivatives (6-13), the pentacyclic triterpene bryonolic acid (5) and two hydroxybenzoic acid amides (3, 4). Their structures were elucidated by spectroscopic analysis, including 2D NMR techniques.
Sahranavard
Shamim
S
Pharmacognosy Department, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. ssahranavard@itmrc.org
Naghibi
Farzaneh
F
Siems
Karsten
K
Jenett-Siems
Kristina
K
D019817:Benzoic Acid / Q000302:isolation & purification; D029772:Bryonia / Q000737:chemistry*; D006027:Glycosides / Q000302:isolation & purification; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D010936:Plant Extracts; D014315:Triterpenes; C514277:cucurbitane; C038105:cucurbitacin D; D019817:Benzoic Acid; C474429:cucurbitacin C; C074984:bryonolic acid