title: Isolation of ugi four-component condensation primary adducts: a straightforward route to isocoumarins.
abstract: Ugi four-component condensation (Ugi-4CC) between 2-formylbenzoic acid, phenacylamine dimethyl acetal, and isocyanides afforded 1H-isochromen-1-ones (isocoumarins). These products, where structure corresponds to the tautomeric enediamine form of the Ugi-4CC primary adducts, were stable enough to allow their isolation and characterization. Stable isocoumarins were also obtained by employing anilines as the amino component in the Ugi four-component condensation.
authors.affiliation: CRIST, Università di Firenze, Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Faggi
authors.forename: María
authors.initials: M
authors.lastname: García-Valverde
authors.forename: Stefano
authors.initials: S
authors.lastname: Marcaccini
authors.forename: Gloria
authors.initials: G
authors.lastname: Menchi