Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system.
Gattinoni
Sonia
S
DISMA, Università degli Studi di Milano, Via Celoria 2, 20133 Milano, Italy.
De Simone
Chiara
C
Dallavalle
Sabrina
S
Fezza
Filomena
F
Nannei
Raffaella
R
Amadio
Daniele
D
Minetti
Patrizia
P
Quattrociocchi
Gianandrea
G
Caprioli
Antonio
A
Borsini
Franco
F
Cabri
Walter
W
Penco
Sergio
S
Merlini
Lucio
L
Maccarrone
Mauro
M
D000581:Amidohydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D000818:Animals; D063385:Cannabinoid Receptor Modulators / Q000378:metabolism; D002219:Carbamates / Q000008:administration & dosage / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D063388:Endocannabinoids; D006801:Humans; D051379:Mice; D010949:Plasma / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship; D000099252:Fatty Acid Amide Hydrolases
D000581:Amidohydrolases; D063385:Cannabinoid Receptor Modulators; D002219:Carbamates; D063388:Endocannabinoids; D000099252:Fatty Acid Amide Hydrolases