title: Mania possibly induced by desvenlafaxine.
abstract: A case is presented of the occurrence of an episode of mania apparently induced by desvenlafaxine, in a patient with a history of major depressive disorder and no apparent history of previous mania or hypo-mania. To our knowledge, this is the first such documented case with this new antidepressant. The discussion focuses on the concept of the bipolar spectrum, and how to view patients who have only become manic while taking antidepressants.
authors.affiliation: Department of Psychiatry, Columbia University College of Physicians and Surgeons, USA.
authors.forename: Rachna
authors.initials: R
authors.lastname: Kalia
authors.forename: Rhanda M
authors.initials: RM
authors.lastname: Magsalin
authors.forename: Ahsan Y
authors.initials: AY
authors.lastname: Khan
authors.forename: David A
authors.initials: DA
authors.lastname: Kahn
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000139:chemically induced*; D003511:Cyclohexanols / Q000009:adverse effects* / Q000627:therapeutic use; D003865:Major Depressive Disorder / Q000188:drug therapy; D000069468:Desvenlafaxine Succinate; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000928:Antidepressive Agents; D003511:Cyclohexanols; D000069468:Desvenlafaxine Succinate