title: Anal neoplasms.
abstract: A variety of lesions comprise tumors of the anal canal, with carcinoma in situ and epidermoid cancers being the most common. Less common anal neoplasms include adenocarcinoma, melanoma, gastrointestinal stromal cell tumors, neuroendocrine tumors, and Buschke-Lowenstein tumors. Treatment strategies are based on anatomic location and histopathology. In this article different tumors and management of each, including a brief review of local excision for rectal cancer, are discussed in turn.
authors.affiliation: Department of Colorectal Surgery, Digestive Disease Institute, 9500 Euclid Avenue, A30 Cleveland Clinic, Cleveland, OH 44195, USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Garrett
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Kalady
mesh_terms: D001005:Anus Neoplasms / Q000473:pathology / Q000601:surgery*; D002278:Carcinoma in Situ / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D018289:Carcinoma, Verrucous / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D011379:Prognosis; D012004:Rectal Neoplasms / Q000601:surgery