title: Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder.
abstract: Improved diagnosis and treatment of traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) are needed for our military and veterans, their families, and society at large. Advances in brain imaging offer important biomarkers of structural, functional, and metabolic information concerning the brain. This article reviews the application of various imaging techniques to the clinical problems of TBI and PTSD. For TBI, we focus on findings and advances in neuroimaging that hold promise for better detection, characterization, and monitoring of objective brain changes in symptomatic patients with combat-related, closed-head brain injuries not readily apparent by standard computed tomography or conventional magnetic resonance imaging techniques.
authors.affiliation: Mild Traumatic Brain Injury Clinic, Irwin Army Community Hospital, 600 Caisson Hill Road, Fort Riley, KS 66442, USA. Robert.vanboven@us.army.mil
authors.forename: Robert W
authors.initials: RW
authors.lastname: Van Boven
authors.forename: Greg S
authors.initials: GS
authors.lastname: Harrington
authors.forename: David B
authors.initials: DB
authors.lastname: Hackney
authors.forename: Andreas
authors.initials: A
authors.lastname: Ebel
authors.forename: Grant
authors.initials: G
authors.lastname: Gauger
authors.forename: J Douglas
authors.initials: JD
authors.lastname: Bremner
authors.forename: Mark
authors.initials: M
authors.lastname: D'Esposito
authors.forename: John A
authors.initials: JA
authors.lastname: Detre
authors.forename: E Mark
authors.initials: EM
authors.lastname: Haacke
authors.forename: Clifford R
authors.initials: CR
authors.lastname: Jack
authors.forename: William J
authors.initials: WJ
authors.lastname: Jagust
authors.forename: Denis
authors.initials: D
authors.lastname: Le Bihan
authors.forename: Chester A
authors.initials: CA
authors.lastname: Mathis
authors.forename: Susanne
authors.initials: S
authors.lastname: Mueller
authors.forename: Pratik
authors.initials: P
authors.lastname: Mukherjee
authors.forename: Norbert
authors.initials: N
authors.lastname: Schuff
authors.forename: Anthony
authors.initials: A
authors.lastname: Chen
authors.forename: Michael W
authors.initials: MW
authors.lastname: Weiner
mesh_terms: D001753:Blast Injuries / Q000175:diagnosis / Q000473:pathology; D001930:Brain Injuries / Q000175:diagnosis* / Q000473:pathology; D056324:Diffusion Tensor Imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D049268:Positron-Emission Tomography; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis* / Q000473:pathology