Effect of an immunization program on seasonal influenza hospitalizations in Mexican children.
We analyzed 2378 respiratory samples of children <5 years of age admitted during a 7-year period in order to determine the contribution of seasonal influenza as a cause of hospitalizations, as well as the impact of the inclusion of influenza vaccine in the childhood immunization program. The presence of influenza virus was demonstrated in 106 (4.4%) samples. The proportion of influenza hospitalizations after the introduction of influenza vaccination was lower (3.4%) than before the establishment of this vaccination program (7.5%; P=0.00002). Our study shows that influenza vaccination programs in children significantly reduce the impact of influenza related hospitalizations.
Aranda-Romo
Saray
S
Microbiology Department, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza 2405, San Luis Potosí 78210, S.L.P., Mexico.
Comas-García
Andreu
A
García-Sepúlveda
Christian A
CA
Hernández-Salinas
Alba E
AE
Piña-Ramírez
Marisol
M
Noyola
Daniel E
DE
D002675:Child, Preschool; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D017589:Immunization Programs / Q000706:statistics & numerical data*; D007223:Infant; D007231:Infant, Newborn; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D009975:Orthomyxoviridae / Q000302:isolation & purification; D015995:Prevalence; D012141:Respiratory Tract Infections / Q000821:virology
D007252:Influenza Vaccines