title: Effect of the degree of fragmentation on embryo survival after freeze-thawing.
abstract: OBJECTIVE
  To determine if the degree of fragmentation of embryos prior to freezing correlate in a negative manner with survival after thawing.
  
  
  METHODS
  A retrospective review of frozen embryos thawed for purposes of embryo transfer was done. Survival and transferability rates were determined according to degree of fragmentation.
  
  
  RESULTS
  The chance that an embryo with < 25% fragmentation was deemed good enough for transfer upon thawing was 63.6% compared to 52.8% for embryos > 25% (p < .05).
  
  
  CONCLUSIONS
  Though more fragmented embryos have a lower survival rate after freeze thawing, about 50% of embryos with > 25% fragmentation will still survive the thaw and be able to be transferred.
authors.affiliation: The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: K
authors.initials: K
authors.lastname: Swenson
authors.forename: W
authors.initials: W
authors.lastname: Yuan
authors.forename: A
authors.initials: A
authors.lastname: Nazari
mesh_terms: D015925:Cryopreservation; D004624:Embryo Transfer; D004622:Embryo, Mammalian; D006801:Humans; D012189:Retrospective Studies; D016019:Survival Analysis