title: Palladium(II)-catalyzed oxidative C-H/C-H cross-coupling of heteroarenes.
abstract: An efficient methodology for the synthesis of unsymmetrical biheteroaryl molecules has been developed via Pd(II)-catalyzed oxidative C-H/C-H cross-coupling of heteroarenes. An inversion in reactivity and selectivity has been achieved successfully to perform the desired heterocoupling. This process allows the heterocoupling of not only electron-rich N-containing heteroarenes (e.g., xanthines, azoles, and indolizines) but also electron-poor pyridine N-oxides with various thiophenes or furans.
authors.affiliation: Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, PR China.
authors.forename: Peihua
authors.initials: P
authors.lastname: Xi
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Song
authors.initials: S
authors.lastname: Qin
authors.forename: Dongbing
authors.initials: D
authors.lastname: Zhao
authors.forename: Jingbo
authors.initials: J
authors.lastname: Lan
authors.forename: Ge
authors.initials: G
authors.lastname: Gao
authors.forename: Changwei
authors.initials: C
authors.lastname: Hu
authors.forename: Jingsong
authors.initials: J
authors.lastname: You
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004583:Electrons; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D010165:Palladium; D002244:Carbon; D006859:Hydrogen