[A case of monozygotic twins with Crohn's disease].
Although the incidence and prevalence rates of IBD in Korea are still lower than Western populations, they have been increasing rapidly during the past decades. Crohn's disease (CD) tends to run in families because it is thought to be related to genetic susceptibility coupled with environmental factors. A large number of monozygotic and dizygotic twin pairs with inflammatory bowel disease have been reported in western countries. The population relative risk in first-degree relatives is considered to be about equal in both Koreans and westerners. To our best knowledge, there is no report in monozygotic twins with CD in Korea. This case report is the first documented occurrence of concordant CD occurring in monozygotic twins in Korea.
Park
Soo Kyung
SK
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kim
Kyung Jo
KJ
Ye
Byong Duk
BD
Byeon
Jeong Sik
JS
Myung
Seung Jae
SJ
Yang
Suk Kyun
SK
Kim
Jin Ho
JH
Chi
Hyun Sook
HS
D000293:Adolescent; D000963:Antimetabolites / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D003113:Colonoscopy; D003424:Crohn Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D004200:Diseases in Twins / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D006801:Humans; D008297:Male; D010375:Pedigree; D014057:Tomography, X-Ray Computed; D014430:Twins, Monozygotic / Q000235:genetics*
D000963:Antimetabolites; D001379:Azathioprine