Synthesis of the conformationally constrained tyrosine analogues, (R)- and (S)-5-hydroxy-2-aminoindan-2-carboxylic acids.
The conformationally constrained tyrosine analogues, (R)- and (S)-5-hydroxy-2-aminoindan-2-carboxylic acids, were prepared by chromatographic separation of diastereomeric dipeptide derivatives formed from N-Boc-L-phenylalanine. Absolute configurations were assigned by X-ray crystallographic analysis.
Murigi
Francis N
FN
Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721-0041, USA.
Nichol
Gary S
GS
Mash
Eugene A
EA
D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry*; D007189:Indans / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D010649:Phenylalanine / Q000737:chemistry*; D013237:Stereoisomerism; D014443:Tyrosine / Q000138:chemical synthesis* / Q000737:chemistry
D004151:Dipeptides; D007189:Indans; D014443:Tyrosine; D010649:Phenylalanine