Bone: adiposity and bone accrual-still an established paradigm?
The paradigm that obesity at any age is protective against skeletal failure has been ingrained in clinical practice for several decades. A new study published in the Journal of Bone and Mineral Research challenges the basic framework of that tenet.
Kawai
Masanobu
M
Skeletal Research Laboratory, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074-7205, USA.
Rosen
Clifford J
CJ
D050154:Adiposity; D000293:Adolescent; D000328:Adult; D015519:Bone Density; D002648:Child; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications; D010012:Osteogenesis; D015663:Osteoporosis, Postmenopausal; D012307:Risk Factors