title: Unexpectedly difficult intubation caused by subglottic stenosis in Wegener's granulomatosis.
abstract: A 76-year-old woman was scheduled to undergo abdominal aortic repair for progressive abdominal aortic aneurysm. After inducing general anesthesia, the 7.5-mm internal diameter (ID) tracheal tube could not be advanced below the level of the vocal cords because of resistance, and intubation was re-attempted several times using smaller tubes. An otolaryngologist was consulted and subglottic stenosis of unknown origin was suggested. The aortic repair was cancelled and tracheostomy was performed instead. She was diagnosed with Wegener's granulomatosis 46 days after the operation because she developed symptoms of renal dysfunction, hemoptysis, gastrointestinal bleeding, and presence of anti-neutrophil cytoplasmic autoantibodies (c-ANCA). The patient was treated with steroids but died 89 days after the operation because of pulmonary bleeding and renal dysfunction. Tracheal stenosis is a rare presenting feature of Wegener's granulomatosis that usually occurs late in the disease; however, anesthesiologists around the world need to bear in mind that the disease can present airway symptoms and can be the cause of airway obstruction.
authors.affiliation: Department of Anesthesia, Otsu Red Cross Hospital, 1-1-35 Nagara, Otsu, Shiga, 520-8511, Japan. hirokidaijo412@gmail.com
authors.forename: Hiroki
authors.initials: H
authors.lastname: Daijo
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takabuchi
authors.forename: Toyohiko
authors.initials: T
authors.lastname: Ohigashi
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Tetsutaro
authors.initials: T
authors.lastname: Shinomura
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D007828:Laryngoscopy; D014135:Tracheal Stenosis / Q000209:etiology*; D014139:Tracheostomy