title: Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza.
abstract: During the 2006-2007 season, 19 HIV-uninfected and 33 HIV-infected children and adolescents with full immunovirologic response to HAART were immunized against influenza and subsequently followed up. One month post-immunization all subjects had protective antibodies titres which persisted for the whole influenza season. Seven vaccinees (four HIV-infected and three HIV-uninfected) were found to be infected by influenza viruses during the epidemic, but disease was lab-confirmed only in two HIV-infected subjects. Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination.
authors.affiliation: Università degli Studi di Milano, Dipartimento di Sanità Pubblica-Microbiologia-Virologia, Via Pascal 36, 20133 Milan, Italy. antonella.amendola@unimi.it
authors.forename: Antonella
authors.initials: A
authors.lastname: Amendola
authors.forename: Elena
authors.initials: E
authors.lastname: Pariani
authors.forename: Alessandra
authors.initials: A
authors.lastname: Viganò
authors.forename: Paola
authors.initials: P
authors.lastname: Erba
authors.forename: Alessandra
authors.initials: A
authors.lastname: Zappa
authors.forename: Vania
authors.initials: V
authors.lastname: Giacomet
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Tanzi
authors.forename: Gian Vincenzo
authors.initials: GV
authors.lastname: Zuccotti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zanetti
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control*; D008297:Male; D016896:Treatment Outcome
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines