title: Knowledge of cervical cancer prevention and human papillomavirus among women with HIV.
abstract: OBJECTIVE
  To assess knowledge of and attitudes towards human papillomavirus (HPV), Pap testing, and the HPV vaccine.
  
  
  METHODS
  In a multicenter U.S. cohort study, women with the human immunodeficiency virus (HIV) and at-risk comparison women completed 44-item standardized self-report questionnaires exploring their knowledge of cervical cancer prevention, HPV, and HPV vaccination. Results were correlated with demographic variables, measures of education and attention, and medical factors. Data were clustered using principal component analysis. Significant associations were assessed in multivariable models.
  
  
  RESULTS
  Among 1588 women, HIV seropositive women better understood facts about cervical cancer prevention and HPV than seronegative women, but both had substantial knowledge deficits. Almost all women considered Pap testing important, although 53% of HIV seropositive and 48% of seronegative women considered cervical cancer not preventable (P=0.21). Only 44% of HIV seropositive women knew Paps assess the cervix, versus 42% of HIV seronegative women (P=0.57). Both groups understood that HPV causes genital warts and cervical cancer (67% of HIV seropositive vs. 55% of seronegative women, P=0.002). About half of both groups considered HPV vaccination extremely important for cervical cancer prevention. HIV seronegative women were more likely to report learning of HPV vaccination through advertising than from clinicians (81% vs. 64%, P<0.0001).
  
  
  CONCLUSIONS
  High risk women need effective education about cervical cancer prevention, HPV, and HPV vaccination.
authors.affiliation: Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA. massadl@wudosis.wustl.edu
authors.forename: L Stewart
authors.initials: LS
authors.lastname: Massad
authors.forename: Charlesnika T
authors.initials: CT
authors.lastname: Evans
authors.forename: Tracey E
authors.initials: TE
authors.lastname: Wilson
authors.forename: Johanna L
authors.initials: JL
authors.lastname: Goderre
authors.forename: Nancy A
authors.initials: NA
authors.lastname: Hessol
authors.forename: Donna
authors.initials: D
authors.lastname: Henry
authors.forename: Christine
authors.initials: C
authors.lastname: Colie
authors.forename: Howard D
authors.initials: HD
authors.lastname: Strickler
authors.forename: Alexandra M
authors.initials: AM
authors.lastname: Levine
authors.forename: D Heather
authors.initials: DH
authors.lastname: Watts
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Weber
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000523:psychology / Q000821:virology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000150:complications* / Q000523:psychology / Q000821:virology; D053918:Papillomavirus Vaccines / Q000008:administration & dosage; D010353:Patient Education as Topic; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control* / Q000523:psychology / Q000821:virology*
chemical_list: D053918:Papillomavirus Vaccines