Contributions of estrogen receptor-α and estrogen receptor-ß to the regulation of behavior.
Studies of the mechanisms by which estrogens influence brain function and behavior have advanced from the explication of individual hormone receptors, neural circuitry and individual gene expression. Now, we can report patterns of estrogen receptor subtype contributions to patterns of behavior. Moreover, new work demonstrates important contributions of nuclear receptor coactivator expression in the central nervous system. In this paper, our current state of knowledge is reviewed.
Tetel
Marc J
MJ
Neuroscience Program, Wellesley College, Wellesley, MA, USA.
Pfaff
Donald W
DW
D000818:Animals; D001519:Behavior / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology*; D047628:Estrogen Receptor alpha / Q000378:metabolism*; D047629:Estrogen Receptor beta / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D008297:Male
C506487:ESR1 protein, human; D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta