Pregnancy rates per embryo transfer (ET) may be improved by conventional oocyte insemination for male factor rather than intracytoplasmic sperm injection (ICSI).
OBJECTIVE
To determine if intracytoplasmic sperm injection (ICSI) for mild male factor may create embryos less likely to implant.


METHODS
A retrospective analysis of pregnancy outcome following oocyte fertilization with ICSI vs conventional egg insemination was performed.


RESULTS
Though there were many less cases using conventional oocyte insemination compared to ICSI so that a meaningful comparison of outcome could not be made, the data could suggest the fertilization by ICSI might result in embryos less likely to implant.


CONCLUSIONS
This pilot study should encourage IVF centers to consider conventional oocyte insemination for mild male factor instead of ICSI. Only by evaluating a larger series can it be determined with certainty that fertilization by ICSI may lower the implantation potential of the embryo that is formed.
Check
J H
JH
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
Katsoff
B
B
Summers-Chase
D
D
Yuan
W
W
Horwath
D
D
Choe
J K
JK
D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007315:Insemination, Artificial; D008297:Male; D010865:Pilot Projects; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects*; D016896:Treatment Outcome