title: Effect of an immunization program on seasonal influenza hospitalizations in Mexican children.
abstract: We analyzed 2378 respiratory samples of children <5 years of age admitted during a 7-year period in order to determine the contribution of seasonal influenza as a cause of hospitalizations, as well as the impact of the inclusion of influenza vaccine in the childhood immunization program. The presence of influenza virus was demonstrated in 106 (4.4%) samples. The proportion of influenza hospitalizations after the introduction of influenza vaccination was lower (3.4%) than before the establishment of this vaccination program (7.5%; P=0.00002). Our study shows that influenza vaccination programs in children significantly reduce the impact of influenza related hospitalizations.
authors.affiliation: Microbiology Department, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza 2405, San Luis Potosí 78210, S.L.P., Mexico.
authors.forename: Saray
authors.initials: S
authors.lastname: Aranda-Romo
authors.forename: Andreu
authors.initials: A
authors.lastname: Comas-García
authors.forename: Christian A
authors.initials: CA
authors.lastname: García-Sepúlveda
authors.forename: Alba E
authors.initials: AE
authors.lastname: Hernández-Salinas
authors.forename: Marisol
authors.initials: M
authors.lastname: Piña-Ramírez
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Noyola
mesh_terms: D002675:Child, Preschool; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D017589:Immunization Programs / Q000706:statistics & numerical data*; D007223:Infant; D007231:Infant, Newborn; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D009975:Orthomyxoviridae / Q000302:isolation & purification; D015995:Prevalence; D012141:Respiratory Tract Infections / Q000821:virology
chemical_list: D007252:Influenza Vaccines