Benzotetramisole-catalyzed dynamic kinetic resolution of azlactones.
Enantioselective acyl transfer catalyst benzotetramisole (BTM) has been found to promote dynamic kinetic resolution of azlactones providing di(1-naphthyl)methyl esters of alpha-amino acids with up to 96% ee.
Yang
Xing
X
Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.
Lu
Guojian
G
Birman
Vladimir B
VB
D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D004952:Esters; D007700:Kinetics; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013773:Tetramisole / Q000031:analogs & derivatives* / Q000737:chemistry
D000596:Amino Acids; D001372:Aza Compounds; D004952:Esters; D007783:Lactones; C515434:benzotetramisole; D013773:Tetramisole