Knowledge of cervical cancer prevention and human papillomavirus among women with HIV.
OBJECTIVE
To assess knowledge of and attitudes towards human papillomavirus (HPV), Pap testing, and the HPV vaccine.


METHODS
In a multicenter U.S. cohort study, women with the human immunodeficiency virus (HIV) and at-risk comparison women completed 44-item standardized self-report questionnaires exploring their knowledge of cervical cancer prevention, HPV, and HPV vaccination. Results were correlated with demographic variables, measures of education and attention, and medical factors. Data were clustered using principal component analysis. Significant associations were assessed in multivariable models.


RESULTS
Among 1588 women, HIV seropositive women better understood facts about cervical cancer prevention and HPV than seronegative women, but both had substantial knowledge deficits. Almost all women considered Pap testing important, although 53% of HIV seropositive and 48% of seronegative women considered cervical cancer not preventable (P=0.21). Only 44% of HIV seropositive women knew Paps assess the cervix, versus 42% of HIV seronegative women (P=0.57). Both groups understood that HPV causes genital warts and cervical cancer (67% of HIV seropositive vs. 55% of seronegative women, P=0.002). About half of both groups considered HPV vaccination extremely important for cervical cancer prevention. HIV seronegative women were more likely to report learning of HPV vaccination through advertising than from clinicians (81% vs. 64%, P<0.0001).


CONCLUSIONS
High risk women need effective education about cervical cancer prevention, HPV, and HPV vaccination.
Massad
L Stewart
LS
Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA. massadl@wudosis.wustl.edu
Evans
Charlesnika T
CT
Wilson
Tracey E
TE
Goderre
Johanna L
JL
Hessol
Nancy A
NA
Henry
Donna
D
Colie
Christine
C
Strickler
Howard D
HD
Levine
Alexandra M
AM
Watts
D Heather
DH
Weber
Kathleen M
KM
D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000523:psychology / Q000821:virology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000150:complications* / Q000523:psychology / Q000821:virology; D053918:Papillomavirus Vaccines / Q000008:administration & dosage; D010353:Patient Education as Topic; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control* / Q000523:psychology / Q000821:virology*
D053918:Papillomavirus Vaccines