title: Elderly POSSUM, a dedicated score for prediction of mortality and morbidity after major colorectal surgery in older patients.
abstract: BACKGROUND
  Several scores have been developed to evaluate surgical unit mortality and morbidity. The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) and derivatives use preoperative and intraoperative factors, whereas the Surgical Risk Scale (SRS) and Association Française de Chirurgie (AFC) score use four simple factors. To allow for advanced age in patients undergoing colorectal surgery, a dedicated score-the Elderly (E) POSSUM-has been developed and its accuracy compared with these scores.
  
  
  METHODS
  From 2002 to 2004, 1186 elderly patients, at least 65 years old, undergoing major colorectal surgery in France were enrolled. Accuracy was assessed by calculating the area under the receiver operating characteristic curve (AUC) (discrimination) and calibration.
  
  
  RESULTS
  The mortality and morbidity rates were 9 and 41 per cent respectively. The E-POSSUM had both a good discrimination (AUC = 0.86) and good calibration (P = 0.178) in predicting mortality and a reasonable discrimination (AUC = 0.77) and good calibration (P = 0.166) in predicting morbidity. The E-POSSUM was significantly better at predicting mortality and morbidity than the AFC score (P(c) = 0.014 and P(c) < 0.001 respectively).
  
  
  CONCLUSIONS
  The E-POSSUM is a good tool for predicting mortality, and the only efficient scoring system for predicting morbidity after major colorectal surgery in the elderly.
authors.affiliation: Biostatistics and Medical Information Unit, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Tran Ba Loc
authors.forename: S Tezenas
authors.initials: ST
authors.lastname: du Montcel
authors.forename: J J
authors.initials: JJ
authors.lastname: Duron
authors.forename: H
authors.initials: H
authors.lastname: Levard
authors.forename: B
authors.initials: B
authors.lastname: Suc
authors.forename: B
authors.initials: B
authors.lastname: Descottes
authors.forename: B
authors.initials: B
authors.lastname: Desrousseaux
authors.forename: J M
authors.initials: JM
authors.lastname: Hay
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000601:surgery*; D017052:Hospital Mortality; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index