title: Malignant transformation of a chronic venous stasis ulcer to basal cell carcinoma in a diabetic patient: case study and review of the pathophysiology.
abstract: The degeneration of chronic wounds into basal cell carcinoma is rare. We present an atypical case of basal cell carcinoma diagnosed by soft tissue biopsy in a long-standing wound that had been treated for 3 years as a chronic venous stasis ulcer. In addition to the case report, we review the biomedical literature describing malignant transformation of long-standing wounds. Foot and ankle specialists should be on the lookout for changes that signal malignant transformation in long-standing ulcers.
authors.affiliation: Faculty Graduate Medical Education, Mercy Hospital Health Systems, Toledo, OH, USA. mjudgemolly@netscape.net
authors.forename: Molly
authors.initials: M
authors.lastname: Schnirring-Judge
authors.forename: Drew
authors.initials: D
authors.lastname: Belpedio
mesh_terms: D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D003922:Diabetes Mellitus, Type 1; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology*; D014647:Varicose Ulcer / Q000473:pathology*