title: Regeneration of periodontal tissues: guided tissue regeneration.
abstract: The concept that only fibroblasts from the periodontal ligament or undifferentiated mesenchymal cells have the potential to re-create the original periodontal attachment has been long recognized. Based on this concept, guided tissue regeneration has been applied with variable success to regenerate periodontal defects. Quantitative analysis of clinical outcomes after guided tissue regeneration suggests that this therapy is a successful and predictable procedure to treat narrow intrabony defects and class II mandibular furcations, but offers limited benefits in the treatment of other types of periodontal defects.
authors.affiliation: Department of Periodontics, The University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, MSC 7894, San Antonio, TX 78229-3900, USA. villar@uthscsa.edu
authors.forename: Cristina C
authors.initials: CC
authors.lastname: Villar
authors.forename: David L
authors.initials: DL
authors.lastname: Cochran
mesh_terms: D020341:Absorbable Implants; D016301:Alveolar Bone Loss / Q000601:surgery*; D002465:Cell Movement; D003239:Connective Tissue Cells; D004847:Epithelial Cells / Q000502:physiology; D017823:Furcation Defects / Q000601:surgery*; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008567:Membranes, Artificial; D008648:Mesoderm / Q000166:cytology; D017622:Periodontal Attachment Loss / Q000601:surgery*; D010513:Periodontal Ligament / Q000166:cytology / Q000502:physiology; D011182:Postoperative Care; D011183:Postoperative Complications
chemical_list: D008567:Membranes, Artificial