title: The treatment of Barrett's esophagus.
abstract: The reflux of the gastric juice in the esophagus can determine the injury of the esophageal epithelium. When the healing of the lesion is done by replacing the normal squamous epithelium with columnar epithelium, the entity is called Barrett's esophagus (BE). Although controversial, some studies showed 0,5% per year the incidence of the esophageal adenocarcinoma in patients with BE, 30 times more often than general population. Taking into consideration the possible development of an adenocarcinoma, the patients with Barrett's esophagus require endoscopic surveillance after a standardized protocol. There is still much controversy about the treatment of patients with Barrett's esophagus, especially in the presence of dysplasia. The aims of the treatment are gastro-esophageal reflux symptoms control, healing of associated esophagitis and prevention of development of adenocarcinoma.
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. petre_hoara@yahoo.com
authors.forename: Petre
authors.initials: P
authors.lastname: Hoara
authors.forename: Cristina
authors.initials: C
authors.lastname: Gindea
authors.forename: Rodica
authors.initials: R
authors.lastname: Birla
authors.forename: Adrian
authors.initials: A
authors.lastname: Mocanu
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Tavlas
authors.forename: Silviu
authors.initials: S
authors.lastname: Constantinoiu
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology / Q000517:prevention & control; D001471:Barrett Esophagus / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000209:etiology / Q000517:prevention & control; D016629:Esophagectomy; D004941:Esophagitis / Q000150:complications / Q000628:therapy; D004945:Esophagoscopy; D005764:Gastroesophageal Reflux / Q000150:complications / Q000628:therapy; D006801:Humans