title: Use of mirtazapine in an adult with refractory anorexia nervosa and comorbid depression: a case report.
abstract: The objective of this report was to describe an efficacious treatment of an adult with long-standing anorexia nervosa (AN). A 50-year-old woman with an over 7-year history of AN and comorbid major depression had been treated unsuccessfully with numerous psychotropic medications, manualized cognitive behavior therapy, and an intensive outpatient treatment program before referral. After treatment with mirtazapine, she gained weight and her depression improved. A 9-month follow-up revealed a maintenance of these benefits. Mirtazapine may be useful for older, chronically ill patients presenting with AN and comorbid depression.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.
authors.forename: Debra L
authors.initials: DL
authors.lastname: Safer
authors.forename: Alison M
authors.initials: AM
authors.lastname: Darcy
authors.forename: James
authors.initials: J
authors.lastname: Lock
mesh_terms: D000856:Anorexia Nervosa / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001835:Body Weight; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008803:Mianserin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D000078785:Mirtazapine; D016896:Treatment Outcome
chemical_list: D000929:Antidepressive Agents, Tricyclic; D008803:Mianserin; D000078785:Mirtazapine