[An approximation to familial colorectal cancer].
Colorectal cancer is one of the most common neoplasms in western countries and is a worldwide public health problem. A substantial number of cases show familial aggregation of the disease, termed familial colorectal cancer to distinguish it from well-established hereditary forms. The present review discusses current knowledge of the underlying genetic causes, the most appropriate screening strategies and the potential prognostic implications of this entity.
Adán
Luisa
L
Servicio de Gastroenterología, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, España.
Alvarez-Castro
Ana
A
Castells
Antoni
A
D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000235:genetics*; D003663:Decision Trees; D005820:Genetic Testing; D006801:Humans