Renal transplant in a child with bilateral Wilms' tumor national premiere.
BACKGROUND
Bilateral Wilmns' tumors with an unfavorable histology requires a combined treatment (extensive surgery, polychimiotherapy, radiotherapy).


OBJECTIVE
Presentation of the first renal transplant performed in Romania in a child with bilateral Wilms' tumor, at 3 years and 4 months after the end of a multimnodal treatment.


METHODS
Patient C. N., born on 30.04.1998, was diagnosed in 04.2001 with right parenchymal renal tumor, polycystic kidney, left cystic renal tumor. 25.04.2001--right radical nephrectomy and partial left upper pole nephrectomy; histopathology examination: triphasic bilateral nephroblastoma, reactive lymph nodes, negative resection edges in the left kidney. 30.04-19.11.2001--polychemotherapy according to the NWTS-5 stages 2-4 focal anaplasia and radiotherapy of the right kidney bed (29.06.2001). 02.2002--a nephrotic syndrome on the remnant kidney which requires its excision and peritoneal dialysis. Abdominal control CT was normal in 03.2005. 11.03.2005- renal transplant from living related donor.


RESULTS
Favorable post-transplant course with normal renal clearance values; at 2 months, normal urography control.


CONCLUSIONS
The tumor pathology does not represent an absolute contraindication for renal transplantation. For the cases with extensive surgery, polychimiotherapy and radiotherapy correctly applied, a pre-transplant "tumor-free" period of at least 2 years is compulsory.
Sinescu
Ioanel
I
Center of Urological Surgery, Dialysis and Renal Transplantation, Fundeni Clinical Institute, Bucharest, Romania. lab2fundeni@cmb.ro
Hârza
Mihai
M
Serbănescu
Bogdan
B
Gîngu
Constantin
C
Stefan
Bogdan
B
Dudu
Cătălin
C
D002675:Child, Preschool; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D007690:Polycystic Kidney Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D012383:Romania; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000000981:diagnostic imaging / Q000601:surgery*