Enantiomerically pure beta-phenylalanine analogues from alpha-beta-phenylalanine mixtures in a single reactive extraction step.
An efficient and selective method for the extraction of alpha-amino acids in preference over their beta-isomers using PdCl(2)(PPh(3))(2) was discovered, which enables the separation of product mixtures obtained in the enantioselective enzymatic formation of beta-amino acids.
Verkuijl
Bastiaan J V
BJ
Organic and Molecular Inorganic Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Szymański
Wiktor
W
Wu
Bian
B
Minnaard
Adriaan J
AJ
Janssen
Dick B
DB
de Vries
Johannes G
JG
Feringa
Ben L
BL
D002384:Catalysis; D002934:Cinnamates / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D010165:Palladium / Q000737:chemistry; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry; D013237:Stereoisomerism
D002934:Cinnamates; D010720:Phosphines; C029010:cinnamic acid; D010649:Phenylalanine; D010165:Palladium; C044646:phosphine