title: Effect of hydration on silk film material properties.
abstract: Effects of hydration on silk fibroin film properties were investigated for water-annealed and MeOH-treated samples. Hydration increased thickness by 60% for MeOH-immersed films, while water-annealed samples remained constant. MeOH-immersed films showed an 80% mass loss due to water, while water-annealed lost only 40%. O(2) permeability was higher in MeOH-immersed films with Dk values of 10(-10) (mL O(2) x cm) x (cm(-1) x s(-1) x mmHg(-1)), while those of water-annealed films reached only one fifth of this value. All films showed a decrease in Young's modulus and increased plastic deformation by two orders of magnitude when submerged in saline solution. FT-IR showed that beta-sheet content in water-annealed films increased with increasing water vapor pressure, while MeOH-immersed films showed no change.
authors.affiliation: Department of Biomedical Engineering, Cornell University, 101 Weill Hall, Ithaca, NY 14853, USA.
authors.forename: Brian D
authors.initials: BD
authors.lastname: Lawrence
authors.forename: Scott
authors.initials: S
authors.lastname: Wharram
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Kluge
authors.forename: Gary G
authors.initials: GG
authors.lastname: Leisk
authors.forename: Fiorenzo G
authors.initials: FG
authors.lastname: Omenetto
authors.forename: Mark I
authors.initials: MI
authors.lastname: Rosenblatt
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
mesh_terms: D000042:Absorption; D001672:Biocompatible Materials / Q000737:chemistry*; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D005349:Fibroins / Q000737:chemistry; D006358:Hot Temperature; D008422:Materials Testing; D000432:Methanol / Q000737:chemistry; D018625:Microscopy, Atomic Force; D018613:Microscopy, Confocal; D008958:Models, Molecular; D010100:Oxygen / Q000737:chemistry; D010539:Permeability; D017433:Protein Structure, Secondary; D012212:Rheology; D047011:Silk / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013718:Tensile Strength; D044366:Transition Temperature; D014867:Water / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D004129:Dimethylpolysiloxanes; D047011:Silk; D014867:Water; D005349:Fibroins; D010100:Oxygen; D000432:Methanol