Eviction notice: new insights into Rad51 removal from DNA during homologous recombination.
In this issue of Molecular Cell, Ward et al. (2010) identify two genes whose products act redundantly to clear Rad51 from DNA after successful strand invasion, thereby enabling the downstream events of homologous recombination to go smoothly.
Williams
Ashley B
AB
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Michael
W Matthew
WM
D000818:Animals; D017173:Caenorhabditis elegans / Q000201:enzymology* / Q000235:genetics; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D053903:DNA Breaks, Double-Stranded; D004260:DNA Repair / Q000235:genetics / Q000502:physiology*; D018509:DNA, Helminth / Q000378:metabolism*; D008540:Meiosis; D008957:Models, Genetic; D051135:Rad51 Recombinase / Q000378:metabolism*; D011995:Recombination, Genetic
D029742:Caenorhabditis elegans Proteins; D018509:DNA, Helminth; D051135:Rad51 Recombinase; C495148:rad-51 protein, C elegans