Rabson-Mendenhall syndrome: two case reports and a brief review of the literature.
Rabson-Mendenhall syndrome is a rare, autosomal recessive disorder characterized by insulin resistance syndrome, growth retardation, coarse and senile-looking faces, mental precocity, early dentition, and pineal hyperplasia. Mutations of the insulin receptor gene affecting insulin action appear to be the basic mechanism underlying this syndrome. We report on Rabson-Mendenhall syndrome in two siblings and briefly review the literature.
Bathi
Renuka J
RJ
Department of Oral Medicine & Radiology, School of Dental Sciences, Sharda University (Deemed University), Plot #32-34, Knowledge Park III, Greater Noida, U. P., 201306, India. renukabathi@yahoo.com
Parveen
Sameena
S
Mutalik
Sunil
S
Rao
Reema
R
D000293:Adolescent; D002675:Child, Preschool; D056731:Donohue Syndrome / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008310:Malocclusion / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D035781:Siblings; D014076:Tooth Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy