Enhanced global genome nucleotide excision repair reduces UV carcinogenesis and nullifies strand bias in p53 mutations in Csb-/- mice.
Pines
Alex
A
Hameetman
Liesbeth
L
de Wilde
Jillian
J
Alekseev
Sergey
S
de Gruijl
Frank R
FR
Vrieling
Harry
H
Mullenders
Leon H F
LH
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology / Q000517:prevention & control*; D003057:Cockayne Syndrome / Q000235:genetics; D004260:DNA Repair / Q000235:genetics / Q000502:physiology*; D045643:DNA Repair Enzymes / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D004195:Disease Models, Animal; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation / Q000235:genetics*; D009381:Neoplasms, Radiation-Induced / Q000503:physiopathology / Q000517:prevention & control; D000075223:Poly-ADP-Ribose Binding Proteins; D012878:Skin Neoplasms / Q000503:physiopathology / Q000517:prevention & control*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics* / Q000378:metabolism; D014466:Ultraviolet Rays / Q000009:adverse effects*
D004268:DNA-Binding Proteins; C496850:Ddb2 protein, mouse; D000075223:Poly-ADP-Ribose Binding Proteins; D016159:Tumor Suppressor Protein p53; C513075:Ercc6 protein, mouse; D045643:DNA Repair Enzymes