Current knowledge of the pre-autophagosomal structure (PAS).
Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells.
Advanced Research Organization, Integrated Research Institute, Tokyo Institute of Technology, Midori-ku, Yokohama, Japan.
Kuninori
K
Suzuki
Yoshinori
Y
Ohsumi
D000818:Animals; D001343:Autophagy / Q000235:genetics; D008954:Models, Biological; D010588:Phagosomes / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism
D029701:Saccharomyces cerevisiae Proteins