[Congenital malformations among offspring of the liquidators of the consequences from Chernobyl accident].
The frequency and the structure of congenital malformations at children of the liquidators of the consequences from Chernobyl accident, undergone to an external scale gamma-irradiation in dozes up to 25 cGy. In total is surveyed 2379 newborn at which is revealed 318 intrauterine development defects. The received results are compared to the earlier published data on birth of congenital malformations in families of the fathers who have undergone to an irradiation in connection with professional activity at the enterprises of a nuclear industry, with emergency irradiation, with irradiation as a result of explosions of nuclear bombs in Japan, and are discussed from positions of the basic rules (situations) of radiating genetics. Total frequency, the frequency of forms 21 of inherent defects of development, taken into account in the International register of congenital malformations and frequency 9 forms heaviest of congenital intrauterine development defects with the high contribution mutation components at children of the liquidators authentically is higher than on the average on Russian Federation. The dependence of the frequency congenital malformations at children from dozes of an irradiation of the fathers--liquidators is revealed. The curve of dependence of the frequency of congenital malformations from time, past after work up to copulation carries arched character with peak of rise of frequency of congenital malformations in 2-3 years and decrease in 6-7 years.
Liaginskaia
A M
AM
Tukov
A R
AR
Osipov
V A
VA
Ermalitskiĭ
A P
AP
Prokhorova
O N
ON
D000016:Abnormalities, Radiation-Induced / Q000145:classification / Q000453:epidemiology*; D047852:Chernobyl Nuclear Accident; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016273:Occupational Exposure; D018812:Paternal Exposure; D012426:Russia / Q000453:epidemiology; D013997:Time Factors; D014455:Ukraine / Q000453:epidemiology