Correlation between pre-operative brain magnetic resonance angiography findings and intra-operative cerebral oxygen saturation during coronary artery bypass graft surgery.
Coronary artery bypass graft (CABG) patients often have cerebrovascular disease and pre-operative brain magnetic resonance angiography (MRA) frequently reveals cerebral vasculature stenosis. This study was designed to investigate whether pre-operative MRA findings correlated with regional cerebral oxygen saturation (ScO(2)) in 120 patients undergoing on-pump or off-pump CABG. Following MRA examination, patients were divided into six groups of 20 patients each based on MRA findings (no stenosis, mild stenosis or severe stenosis) and procedure (on-pump or off-pump CABG). Mean ScO(2) values over 3 min were determined at seven periods during surgery. Patients with severe cerebrovascular stenosis showed significantly lower ScO(2) than other groups during off-pump CABG. During on-pump CABG, ScO(2) decreased significantly during cardiopulmonary bypass in all groups and was significantly lower in the severe stenosis group. Pre-operative MRA and intra-operative ScO(2) monitoring may help to identify patients at increased risk of brain damage during or following CABG.
Department of Anaesthesiology, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Y-J
YJ
Roh
J-W
JW
Choi
J-H
JH
Suh
J-Y
JY
Shim
I-C
IC
Choi
D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D001026:Coronary Artery Bypass; D003710:Demography; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D057234:Preoperative Period; D011859:Radiography
D010100:Oxygen