[Experience of transcather closure in patients with postinfarction ventricular septal defects].
OBJECTIVE
To evaluate the therapeutic effect of transcather closure in patients with postinfarction ventricular septal defects (VSD).


METHODS
Transcatheter VSD closure was performed in 12 patients with postinfarction VSD (10 muscular and 2 membranes defects) on top of standard pharmacotherapy and percutaneous transluminal coronary angioplasty (PTCA) as indicated.


RESULTS
(1) Percutaneous interventional VSD closure was successful in 9 out 12 patients (75%) and these 9 patients survived post procedure. (2) The medial time between VSD occurrence and closure was (15.5 +/- 9.2) days. Procedure-related complications such as device embolization and malignant arrhythmia occurred in 3 patients (25%). The medial time between procedure and discharge from hospital was (11.3 +/- 5.2) days. (3) Coronary angiography was performed in 2 patients and 4 stents were implanted in diseased lesions.


CONCLUSIONS
Transcatheter closure could be successfully performed in selected patients with postinfarction VSD.
Department of Cardiovascular Diseases, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Yong
Y
Sun
Jie
J
Yuan
Ruo-Xi
RX
Zhang
Bo
B
Yu
D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization / Q000009:adverse effects; D003131:Combined Modality Therapy; D006345:Heart Septal Defects, Ventricular / Q000209:etiology / Q000628:therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications* / Q000188:drug therapy; D015607:Stents; D016896:Treatment Outcome