Bleomycin sclerotherapy in a rare case of adult-onset cervical lymphangioma.
Cervical lymphangioma in adults is a rare, benign tumor. Traditionally, the most accepted treatment has been surgical excision. However, when lymphangioma infiltrates vital neurovascular structures, excision is difficult and recurrence rates are high. The most common alternate treatment is intralesional injection of sclerosing agents, which has resulted in good outcomes in children. However, until now, no report of such treatment in adults has been published. We describe the case of a 60-year-old woman who presented with two lymphangiomas in the cervical area-one in the upper cervical area just below the angle of the mandible and the other in the submental area. She was treated with an intralesional injection of 1 mg/kg of bleomycin at both sites. Fifteen days later, the submental swelling had remitted completely and the other swelling had been reduced by 50%; 2 weeks later, a second injection was administered to the remaining swelling. At 6 months of follow-up, both lymphangiomas were in complete remission.
Department of Otorhinolaryngology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. drlvaid@rediffmail.com
Lakshmi
L
Vaid
Manish
M
Gupta
Neelima
N
Gupta
P P
PP
Singh
D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008202:Lymphangioma / Q000188:drug therapy*; D008875:Middle Aged; D009333:Neck; D015911:Sclerotherapy / Q000379:methods*
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin