Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana.
Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo[3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against alpha-glucosidase with IC(50) values of 16.9 microM (1), 23.7 microM (2) and 12.8 microM (3), respectively.
School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
Sio-Hong
SH
Lam
Shoei-Sheng
SS
Lee
D028023:Arecaceae / Q000196:embryology* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D012639:Seeds / Q000378:metabolism*; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification*
D013267:Stilbenes