Diagnosis/differential diagnosis of Cushing's syndrome: a review of best practice.
Endogenous Cushing's syndrome is an uncommon endocrine disorder that can often prove challenging, for both initial diagnosis and subsequent differential diagnosis of the underlying cause. Understanding the advantages and pitfalls of the diagnostic methods used in Cushing's syndrome is essential for accurate diagnosis and differential diagnosis, and guidelines outlining the most appropriate approaches have recently been published. We examine how current practice guidelines can be used in a real case-based scenario, and review the recommended strategies to achieve successful diagnosis and differential diagnosis.
Academic Unit of Diabetes, Endocrinology & Metabolism, University of Sheffield Beech Hill Road, Sheffield S10 2RX, UK. j.newellprice@sheffield.ac.uk
John
J
Newell-Price
D000324:Adrenocorticotropic Hormone / Q000378:metabolism / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D003940:Diagnostic Techniques, Endocrine; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000378:metabolism / Q000652:urine; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D012463:Saliva / Q000737:chemistry
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone