Candida albicans-associated necrotizing vasculitis producing life-threatening gastrointestinal hemorrhage.
Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal tract. We explore the association between Candida and such vasculopathy.
Sargent
Jeremy
J
Department of Hematology, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.
O'Marcaigh
Aengus
A
Smith
Owen
O
Butler
Karina
K
Gavin
Patrick
P
O'Sullivan
Maureen
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications*; D002675:Child, Preschool; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D009336:Necrosis; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology