[Cytokine therapy in the regulation of corneal reparative processes: an experimental and clinical study].
Cytokine monotherapy with Superlymph used in combination with the keratoprotector Applicoll in the treatment of superficial corneal layer defect resulted in rapidly alleviated inflammatory reactions, accelerated reparative processes, more qualitative epithelial defect recovery, by forming a finer scar, without opacity whereas the traditional treatment led to long-term healing and keratoleukoma in an experiment. The use of cytokine therapy with Superlymph in the complex treatment of corneal injuries and inflammation in children promoted a prompt and stable arrest of a local inflammatory process, accelerated epithelization, reduced opacity intensity, higher visual acuity, and shorter treatment.
Dzhambinova
N S
NS
Guseva
M R
MR
Sidorenko
E I
EI
Gankovskaia
L V
LV
Koval'chuk
L V
LV
Fedorov
A A
AA
Gorbunova
E D
ED
Kuznetsova
Iu D
IuD
D000293:Adolescent; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology; D065306:Corneal Injuries; D003318:Corneal Opacity / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D016207:Cytokines / Q000008:administration & dosage / Q000627:therapeutic use*; D004195:Disease Models, Animal; D005131:Eye Injuries / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007634:Keratitis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009883:Ophthalmic Solutions; D011817:Rabbits; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
D016207:Cytokines; D009883:Ophthalmic Solutions