Therapeutic Hotline: Topical glycopyrrolate: a successful treatment for craniofacial hyperhidrosis and eccrine hidrocystomas.
Eccrine hidrocystoma is a benign tumor derived from eccrine sudoriparous glands. Most eccrine hidrocystomas are solitary and asymptomatic lesions. Multiple hidrocystomas are unusual and have been associated with Graves' disease, Parkinson's disease, and idiopathic craniofacial hyperhidrosis. This report describes the successful treatment of multiple center facial eccrine hidrocystomas associated with craniofacial hyperhidrosis with 0.5% glycopyrrolate aqueous solution applied locally for 1 week. The present authors obtained a very significant improvement without leaving any trace of clinical examination. Multiple eccrine hidrocystomas are a rare condition and, to date, no effective treatment has been reported. Topical glycopyrrolate is a very good first-line treatment option.
Garnacho Saucedo
Gloria María
GM
University Hospital "Reina Sofía," Córdoba, Spain. glorina_81@hotmail.com
Moreno Jiménez
José Carlos
JC
Jiménez Puya
Rafael
R
Rodríguez Bujaldon
Alfonso
A
D000279:Administration, Cutaneous; D004439:Eccrine Glands / Q000473:pathology; D005142:Eyelid Neoplasms / Q000188:drug therapy*; D005260:Female; D006024:Glycopyrrolate / Q000008:administration & dosage / Q000627:therapeutic use*; D018251:Hidrocystoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D013544:Sweat Gland Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D018727:Muscarinic Antagonists; D006024:Glycopyrrolate