Forever young.
Propagation of a species requires periodic cell renewal to avoid clonal senescence. Liu et al. (2010) now describe a new mechanism of cell renewal in budding yeast, in which damaged protein aggregates are transported out of the daughter buds along actin cables to preserve youthfulness.
Guarente
Leonard
L
Paul F. Glenn Lab, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. leng@mit.edu
D000199:Actins / Q000378:metabolism; D021381:Protein Transport; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism
D000199:Actins; D029701:Saccharomyces cerevisiae Proteins