[Population study of four X-chromosomal STR loci from the northern part of Poland].
INTRODUCTION, MATERIALS AND METHODS: The allele frequencies of four short tandem repeats (STR) loci specific to the human X chromosome (DXS101, DXS7423, DXS8377 and phosphoribosyltransferase HPRTB) were analyzed by means of a multiplex PCR reaction in a sample of 200 unrelated individuals residing in the northern part of Poland. The separation and detection of PCR products were performed by capillary electrophoresis on the 3130 Genetic Analyzer. Testing for Hardy-Weinberg equilibrium (HWE) showed no significant deviation for these loci.


RESULTS
Statistical parameters such as: heterozygosity observed, mean exclusion chance, power of discrimination in males and power of discrimination in females showed that the examined multiplex is useful in forensic and paternity testing applications.
Katedra i Zakład Medycyny Sadowej Akademii Medycznej w Gdańsku, ul. Debowa 23, 80-204 Gdańsk.
Lidia
L
Cybulska
Ewa
E
Kapińska
Joanna
J
Wysocka
Krzysztof
K
Rebała
Zofia
Z
Szczerkowska
D041321:Chromosomes, Human, X / Q000235:genetics*; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D010334:Paternity; D011044:Poland