Modulation of enzyme activities of a lead-adapted strain of Rhizopus arrhizus during bioaccumulation of lead.
Activity of some enzymes of a Pb-adapted strain of Rhizopus arrhizus augmented significantly during bioaccumulation of Pb from a chemically defined medium. The mycelium of a Pb-adapted strain exposed to 1 microg/mL Pb in a defined medium for 10 d at 28 +/- 2 degrees C exhibited, relative to a wild-type strain, increased activities of antioxidant enzymes, i.e. SOD, CAT and GPX and of enzymes like AP and PPO involved in defense against pathogens. Another response is a significant increase in the cellular thiol content after 4 d. The responses to Pb exposure thus include an increase in the antioxidant and anti-pathogen defense, and an increased metal-chelating ability.
Department of Chemical Technology, University of Calcutta, Kolkata, India. sauryya@hotmail.com
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Basumajumdar
D000935:Antifungal Agents / Q000378:metabolism*; D003470:Culture Media / Q000737:chemistry; D025141:Drug Resistance, Fungal; D004798:Enzymes / Q000378:metabolism*; D005656:Fungal Proteins / Q000378:metabolism*; D007854:Lead / Q000378:metabolism*; D025282:Mycelium / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D012233:Rhizopus / Q000187:drug effects* / Q000201:enzymology* / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000378:metabolism
D000935:Antifungal Agents; D003470:Culture Media; D004798:Enzymes; D005656:Fungal Proteins; D013438:Sulfhydryl Compounds; D007854:Lead