A rare case of sarcoid-like reaction of lymph nodes associated with squamous cell carcinoma of alveolar mucosa.
Non-necrotizing granulomas are occasionally seen in patients with certain malignant disorders and are termed as "sarcoid-like reaction," which have many similarities with sarcoidosis. Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by organ involvement and interference of organ function by granuloma or fibrosis. Sarcoidosis is occasionally found in a variety of malignant diseases with an overall incidence of 4.4% in carcinoma patients. We present here a rare case of moderately differentiated squamous cell carcinoma of alveolar mucosa with regard to mandible associated with sarcoid-like reaction of cervical lymph nodes in a female patient in the absence of clinical evidence of systemic sarcoidosis. The relevant literature including pathogenesis is also discussed.
Department of Oral and Maxillofacial Pathology, Meenakshi Ammal Dental College and Hospital, Alapakkam Main Road, Maduravoyal, Chennai-600 095, Tamil Nadu, India.
Shweta
S
Nag
T R
TR
Saraswathi
Ganthimathy
G
Sekhar
A
A
Einstein
B
B
Sivapathasundharam
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D015726:Giant Cells / Q000473:pathology; D015744:Giant Cells, Langhans / Q000473:pathology; D005887:Gingival Neoplasms / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000473:pathology*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000473:pathology*; D009333:Neck; D019226:Oral Ulcer / Q000473:pathology; D012507:Sarcoidosis / Q000473:pathology*