Analysis of auditory function using brainstem auditory evoked potentials and auditory steady state responses in infants with perinatal brain injury.
Approximately 2-4 % of newborns with perinatal risk factors present hearing loss. The aim of this study was to analyse the auditory function in infants with perinatal brain injury (PBI). Brainstem auditory evoked potentials (BAEPs), auditory steady state responses (ASSRs), and tympanometry studies were carried out in 294 infants with PBI (586 ears, two infants had unilateral microtia-atresia). BAEPs were abnormal in 158 (27%) ears, ASSRs in 227 (39%), and tympanometry anomalies were present in 131 (22%) ears. When ASSR thresholds were compared with BAEPs, the assessment yielded 92% sensitivity and 68% specificity. When ASSR thresholds were compared with tympanometry results as an indicator of middle-ear pathology, the assessment gave 96% sensitivity and 77% specificity. When BAEP thresholds were compared with tympanometry results, sensitivity was 35% and specificity 95%. In conclusion, BAEPs are useful test for neonatal auditory screening; they identify with more accuracy sensorineural hearing losses. ASSRs are more pertinent for identifying conductive hearing loss associated with middle-ear pathology. The consistency and accuracy of these results could be considered in additional studies.
Moreno-Aguirre
Alma Janeth
AJ
Unidad de Investigación en Neurodesarrollo 'Dr. Augusto Fernández Guardiola', Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Querétaro, México.
Santiago-Rodríguez
Efraín
E
Harmony
Thalía
T
Fernández-Bouzas
Antonio
A
Porras-Kattz
Eneida
E
D000158:Acoustic Impedance Tests; D000161:Acoustic Stimulation; D001307:Auditory Perception / Q000502:physiology; D001720:Birth Injuries / Q000150:complications / Q000503:physiopathology; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology*; D001933:Brain Stem / Q000503:physiopathology; D004432:Ear, Middle / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D005315:Fetal Diseases / Q000503:physiopathology; D007839:Functional Laterality; D034381:Hearing Loss / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D049188:Prenatal Injuries / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D013997:Time Factors