Common mechanisms of synaptic plasticity in vertebrates and invertebrates.
Until recently, the literature on learning-related synaptic plasticity in invertebrates has been dominated by models assuming plasticity is mediated by presynaptic changes, whereas the vertebrate literature has been dominated by models assuming it is mediated by postsynaptic changes. Here I will argue that this situation does not reflect a biological reality and that, in fact, invertebrate and vertebrate nervous systems share a common set of mechanisms of synaptic plasticity.
Department of Physiological Science, UCLA College, University of California, Los Angeles, Los Angeles, CA 90095-1606, USA. dglanzman@physci.ucla.edu
David L
DL
Glanzman
D000818:Animals; D049673:History, 20th Century; D007448:Invertebrates / Q000502:physiology*; D007858:Learning / Q000502:physiology; D017774:Long-Term Potentiation; D036881:Long-Term Synaptic Depression; D008959:Models, Neurological; D009473:Neuronal Plasticity / Q000502:physiology*; D012106:Research / Q000266:history; D014714:Vertebrates / Q000502:physiology*