Scaffold-free cell delivery for use in regenerative medicine.
The development of cell-based therapies for diseased tissues is one of the most promising research directions in regenerative medicine. Cell-delivery methods are an essential part of cell therapy concepts. Therapies with the potential to become clinical routine will only be possible if these methods ensure efficient engraftment and therapeutically-relevant number of cells survive. Here we provide an overview of three different scaffold-free cell-delivery concepts: (i) single cell delivery, (ii) cell sheet engineering and (iii) microtissue technology.
Kelm
Jens M
JM
Competence Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Switzerland.
Fussenegger
Martin
M
D000818:Animals; D018929:Cell Culture Techniques; D002470:Cell Survival; D017690:Cell Transplantation / Q000379:methods*; D006801:Humans; D044968:Regenerative Medicine / Q000379:methods*; D033581:Stem Cell Transplantation / Q000379:methods; D023822:Tissue Engineering / Q000379:methods*