Ligand-free copper(I)-catalysed intramolecular direct C-H functionalization of azoles.
The first examples of copper-catalysed intramolecular direct C-arylation of azaheterocycles for the synthesis of complex heterofused compounds is presented, featuring an unprecedented arylation via C-H activation of 9H-purine and 4-azabenzimidazole.
Kimika Organikoa II Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, PO Box 644, 48080, Bilbao, Spain.
Nekane
N
Barbero
Raul
R
Sanmartin
Esther
E
Domínguez