Candida albicans-associated necrotizing vasculitis producing life-threatening gastrointestinal hemorrhage.
Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal tract. We explore the association between Candida and such vasculopathy.
Department of Hematology, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.
Jeremy
J
Sargent
Aengus
A
O'Marcaigh
Owen
O
Smith
Karina
K
Butler
Patrick
P
Gavin
Maureen
M
O'Sullivan
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications*; D002675:Child, Preschool; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D009336:Necrosis; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology