Profiling type I collagen gene expression in growing mandibular structures.
We conducted a temporal gene expression analysis with type I collagen in the coronoid process, alveolar process and mandibular angle of the rat. We observed gene expression cross-sectionally across different important physiological time points in the rat postnatal life in order to observe in which developmental stage mandibular development mainly occur. This study indicates prominent type I collagen expression at day 10 postpartum in the mandibular ramus and at day 21 in the alveolar process. These findings correspond well with previously obtained data from proliferation studies in facial bone suggesting that craniofacial growth in the rat occurs mainly between days 10 and 21.
Römer
P
P
Department of Orthodontics, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany. piero.roemer@gmx.de
Weingärtner
J
J
Proff
P
P
Roldán
J C
JC
Reicheneder
C
C
D000199:Actins / Q000235:genetics; D000539:Alveolar Process / Q000033:anatomy & histology / Q000254:growth & development / Q000378:metabolism; D000818:Animals; D024042:Collagen Type I / Q000235:genetics*; D017931:DNA Primers; D005786:Gene Expression Regulation; D008297:Male; D008334:Mandible / Q000033:anatomy & histology / Q000254:growth & development* / Q000378:metabolism*; D012313:RNA / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D011917:Rats, Inbred Lew; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012741:Sexual Maturation
D000199:Actins; D024042:Collagen Type I; D017931:DNA Primers; D012333:RNA, Messenger; D012313:RNA