[Expression of cytokeratins in tumors with perineural differentiation].
Twenty tumors with perineural differentiation (1 intraneural perineurioma, 10 conventional soft tissue perineuriomas, 3 reticular, 3 sclerosing, 1, atypical, and 2 malignant ones) were studied using a panel of antibodies directed against epithelial antigens. Seven (35%) cases were stained for CK14, 3 (15%) for AE1/AE3, and 2 (10%) for CAMS.2. These tumors showed focal expression of cytokeratins with labeling only a portion of cytoplasm. All tumors were negative for CEA, CK5/6, CK7, CK8, CK10, CK13, CK18, CK19, and CK20. The results of this investigation may be useful in the differential diagnosis of perineural tumors.
Shelekhova
K V
KV
Danilova
A B
AB
D000293:Adolescent; D000328:Adult; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007633:Keratins / Q000096:biosynthesis*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000096:biosynthesis*; D009463:Neuroma / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology
D009363:Neoplasm Proteins; D007633:Keratins