TPR motifs: hallmarks of a new polysaccharide export scaffold.
Bacteria produce a remarkable range of surface and secreted polysaccharides. Two pathways have been defined for the biosynthesis and export of capsular polysaccharides and exopolysaccharides in Gram-negative bacteria. A structure of AlgK described in this issue provides structural insight into a third previously unrecognized pathway associated with important biopolymers (Keiski et al., 2010).
Chris
C
Whitfield
Iain L
IL
Mainprize
D020816:Amino Acid Motifs; D016667:Bacterial Capsules / Q000737:chemistry; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D008958:Models, Molecular; D011135:Polysaccharides, Bacterial / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation
C104798:AlgK protein, Pseudomonas aeruginosa; D001426:Bacterial Proteins; D011135:Polysaccharides, Bacterial