Macular abnormality observed by OCT in children with amblyopia failing to achieve normal visual acuity after long-term treatment.
OBJECTIVE
To investigate why some children with amblyopia fail to achieve normal visual acuity.


METHODS
Optical coherence tomography (OCT) was perform to observe the morphology of the macular tissue of children with various types of amblyopia who failed to achieve normal visual acuity (< or = 20/25). Average thickness of the retinal nerve fiber layer (RNFL) of the foveola and fovea (1-mm diameter range) was then assessed by macular retinal tomography map measurement. The data obtained were compared with those considered normal to detect any abnormality.


RESULTS
Fifteen patients (24 eyes) were examined. Images showed abnormality with thickness RNFL in the macular area in which
Department of Ophthalmology, Province Chinese Medical Hospital, Nanjing, China.
Hong
H
Liu
Lu
L
Zhong
Xin
X
Zhou
Qing-Zi
QZ
Jin
D000293:Adolescent; D000550:Amblyopia / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D005124:Eye Abnormalities / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000002:abnormalities*; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D011379:Prognosis; D012165:Retinal Ganglion Cells / Q000473:pathology; D042262:Retinoscopy; D012683:Sensory Deprivation; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*; D017211:Treatment Failure; D014792:Visual Acuity