[Initial research of customized aberration correction with adaptive optics technique].
OBJECTIVE
To analyze the effects of different wavefront-guided aberration ablation patterns on visual function using adaptive optics technique and explore the effective and feasible pattern of customized refractive surgery.


METHODS
Control study. Under dark condition, six volunteers'right eyes were fully dilated with 5 g/L phenyl ephedrine. The myopia and astigmatism were first fully corrected with optical lens, and then 100% contrast visual acuity of different wavefront correction patterns was detected using adaptive optics system in through a 6.0 mm pupil optical path.


RESULTS
All of the eight different aberration correction strategies obtained excellent correction effect. On the basis of this correction, visual acuity test was performed. The results showed that all aberration correction strategies improved the visual acuity compared with static correction. Correction of high order aberrations and full correction of aberrations could obtain better visual acuity than that of only correction of low order aberrations. Correction of aberrations from second to third order and fourth order spherical aberration second only to full correction of aberration.


CONCLUSIONS
As for low myopia patients, eliminating ocular high order aberrations could improve visual acuity. Correction of aberration from second to third order and fourth spherical aberration might be an effective and feasible pattern of customized refractive surgery.
Li
Shi-ming
SM
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100730, China.
Xiong
Ying
Y
Li
Jing
J
Zhou
Yue-hua
YH
Dai
Yun
Y
Liu
Qian
Q
Xue
Li-xia
LX
Zhang
Yu-dong
YD
Jiang
Wen-han
WH
Wang
Ning-li
NL
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000628:therapy; D055095:Optics and Photonics / Q000379:methods*; D012030:Refractive Errors / Q000628:therapy*; D054140:Refractive Surgical Procedures / Q000379:methods*; D014792:Visual Acuity