Activation instead of inhibition: targeting proenzymes for small-molecule intervention.
Chemical Genomics Centre der Max-Planck-Gesellschaft, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany.
Christian
C
Ottmann
Patrick
P
Hauske
Markus
M
Kaiser
D001549:Benzamides / Q000737:chemistry*; D053148:Caspase 3 / Q000737:chemistry* / Q000378:metabolism; D020134:Catalytic Domain; D003374:Coumarins / Q000737:chemistry*; D004792:Enzyme Precursors / Q000737:chemistry* / Q000378:metabolism; D006835:Hydrazones / Q000737:chemistry*; D010879:Piperazines / Q000737:chemistry*; D011485:Protein Binding; D017434:Protein Structure, Tertiary
C514579:(4-benzylpiperazin-1-yl)acetic acid (3-allyl-2-hydroxybenzylidene)hydrazine; D001549:Benzamides; D003374:Coumarins; D004792:Enzyme Precursors; D006835:Hydrazones; D010879:Piperazines; D053148:Caspase 3