Synthesis of Ag-liposome nano composites.
Silver nanoparticles were synthesized and stabilized by a simple, environment-friendly method in a liposomes structure. Liposomes were prepared by facing lecithin to the aqueous-phase solutions while stirring vigorously. The ratio of lecithin concentration to silver nitrate (K(Lec/Ag) = [Lecithin]/[AgNO(3)]) is the influencing factor in the synthesis of silver nanoparticles. The stability, size distribution, and antibacterial properties of synthesized silver nanoparticles were studied by ultraviolet (UV)-visible, dynamic light scattering, and antibacterial assay. The UV spectra indicated a single symmetric extinction peak at 400 nm, confirming the spherical shape of the synthesized silver nanoparticles. A high K(Lec/Ag) value leads to a reduction in the intensity of extinction spectra and increases the size of Ag-liposomes nanocomposites. The large Ag-liposomes nanocomposites are transformed to the smaller Ag-liposomes nanocomposites (from 342 to 190 nm) due to sonication treatment. The stabilized silver nanoparticles with various lecithin concentrations showed a good antibacterial activity against Staphylococcus aureus, a Gram-positive bacterium, and Escherichia coli, a Gram-negative bacterium.
Barani
Hossein
H
Textile Department, Center of Excellence in Textile, Amirkabir University of Technology, Tehran, Iran.
Montazer
Majid
M
Toliyat
Tayebeh
T
Samadi
Nasrin
N
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008081:Liposomes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053761:Nanocomposites / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D008081:Liposomes; D012834:Silver