Multiple myeloma presenting as recurrent sinopulmonary infections.
Multiple myeloma is a plasma cell malignancy that classically presents with bone pain secondary to osteolytic lesions, anemia, and renal insufficiency. A 49-year-old man presented for workup of possible primary immunodeficiency due to a history of recurrent sinopulmonary infection and abnormal immunoglobulin levels. He was subsequently diagnosed with multiple myeloma, despite a lack of typical symptoms. The correct diagnosis of multiple myeloma can be easily overlooked, especially in a patient with recurrent infections but no other signs or symptoms typical of myeloma.
Department of Internal Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Julia
J
Kang
Amit
A
Kumar
Catherine
C
Monteleone
D001797:Blood Protein Electrophoresis; D006801:Humans; D016867:Immunocompromised Host; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000276:immunology*; D018410:Pneumonia, Bacterial / Q000276:immunology* / Q000517:prevention & control; D012852:Sinusitis / Q000276:immunology* / Q000517:prevention & control
D016756:Immunoglobulins, Intravenous