Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.
Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC).
Organic Chemistry Division, NIIST, Thiruvananthapuram, Kerala, India.
Anabha E
AE
Raveendran
Rony Rajan
RR
Paul
Eringathodi
E
Suresh
Vijay
V
Nair
D000098:Acetophenones / Q000737:chemistry*; D000179:Acrylates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003979:Diazonium Compounds / Q000737:chemistry; D007700:Kinetics; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008956:Models, Chemical; D013237:Stereoisomerism; D013696:Temperature
D000098:Acetophenones; D000179:Acrylates; D003979:Diazonium Compounds; C030011:carbene; C013190:phenacyl bromide; D008697:Methane