Preparation of silver hexacyanoferrate nanoparticles and its application for the simultaneous determination of ascorbic acid, dopamine and uric acid.
A silver hexacyanoferrate nanoparticles/carbon nanotubes modified glassy carbon electrode was fabricated and then successfully used for the simultaneous determination of ascorbic acid, dopamine and uric acid by cyclic voltammetry. A detailed investigation by transmission electron microscopy (TEM) and electrochemistry was performed in order to elucidate the preparation process and properties of the nanocomposites. The size of silver hexacyanoferrate nanoparticles was examined by TEM around 27 nm. Linear calibration plots were obtained over the range of 4.0 x 10(-6)-7.8 x 10(-5), 2.4 x 10(-6)-1.3 x 10(-4) and 2.0 x 10(-6)-1.5 x 10(-4) mol L(-1) with detection limits of 4.2 x 10(-7),1.4 x 10(-7) and 6.0 x 10(-8) mol L(-1) for ascorbic acid, dopamine and uric acid, respectively. The practical analytical utilities of the modified electrode were demonstrated by the determination of ascorbic acid, dopamine and uric acid in urine and human blood serum samples.
Analytical Research Laboratory, Department of Chemistry, University of Sistan & Baluchestan, PO Box 98155-147, Zahedan, Iran. mnoroozifar@chem.usb.ac.ir
Meissam
M
Noroozifar
Mozhgan
M
Khorasani-Motlagh
Aboozar
A
Taheri
D001205:Ascorbic Acid / Q000097:blood* / Q000652:urine*; D015374:Biosensing Techniques / Q000379:methods; D004298:Dopamine / Q000097:blood* / Q000652:urine*; D004563:Electrochemistry / Q000379:methods*; D005295:Ferrocyanides / Q000737:chemistry; D006801:Humans; D057230:Limit of Detection; D016014:Linear Models; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D010084:Oxidation-Reduction; D012834:Silver / Q000737:chemistry; D014527:Uric Acid / Q000097:blood* / Q000652:urine*
D005295:Ferrocyanides; C116383:ferrocyn; D014527:Uric Acid; D012834:Silver; D001205:Ascorbic Acid; D004298:Dopamine