Cowden syndrome.
Mucocutaneous papillomas can be manifestations of an autosomal dominant condition known as Cowden syndrome (CS). We report the case of a 22-year-old man with oral and cutaneous papules and a past history of thyroid malignancy. It is important to recognize oral manifestations of CS; they can lead to early diagnosis of the condition.
Oliveira
Marcio A
MA
Department of Oral Pathology, Special Care Dentistry Center, University of São Paulo, Brazil.
Medina
Janaina B
JB
Xavier
Flavia C
FC
Magalhães
Marina
M
Ortega
Karem L
KL
D042241:Early Diagnosis; D005148:Facial Dermatoses / Q000235:genetics*; D005350:Fibroma / Q000235:genetics*; D005799:Genes, Dominant; D020022:Genetic Predisposition to Disease; D005887:Gingival Neoplasms / Q000235:genetics; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D051059:PTEN Phosphohydrolase / Q000172:deficiency / Q000235:genetics; D013964:Thyroid Neoplasms / Q000235:genetics*; D014062:Tongue Neoplasms / Q000235:genetics; D055815:Young Adult
D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human