A rare case of sarcoid-like reaction of lymph nodes associated with squamous cell carcinoma of alveolar mucosa.
Non-necrotizing granulomas are occasionally seen in patients with certain malignant disorders and are termed as "sarcoid-like reaction," which have many similarities with sarcoidosis. Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by organ involvement and interference of organ function by granuloma or fibrosis. Sarcoidosis is occasionally found in a variety of malignant diseases with an overall incidence of 4.4% in carcinoma patients. We present here a rare case of moderately differentiated squamous cell carcinoma of alveolar mucosa with regard to mandible associated with sarcoid-like reaction of cervical lymph nodes in a female patient in the absence of clinical evidence of systemic sarcoidosis. The relevant literature including pathogenesis is also discussed.
Nag
Shweta
S
Department of Oral and Maxillofacial Pathology, Meenakshi Ammal Dental College and Hospital, Alapakkam Main Road, Maduravoyal, Chennai-600 095, Tamil Nadu, India.
Saraswathi
T R
TR
Sekhar
Ganthimathy
G
Einstein
A
A
Sivapathasundharam
B
B
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D015726:Giant Cells / Q000473:pathology; D015744:Giant Cells, Langhans / Q000473:pathology; D005887:Gingival Neoplasms / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000473:pathology*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000473:pathology*; D009333:Neck; D019226:Oral Ulcer / Q000473:pathology; D012507:Sarcoidosis / Q000473:pathology*