Nasal vestibular huge keratoacanthoma: an unusual site.
Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence. This tumor is dome-shaped nodule with a central keratinous plug. The etiology of this tumor is not obvious. Exposure to excessive sunlight is the most frequently noted responsible factor in the etiology of KA. About 80% of the tumors occur on the face. The histological features of the KA are often very similar to those of a cutaneous squamous cell carcinoma; however, the tumor structure usually provides a basis for their difference. There are many unusual cases of keratoacanthoma reported regarding site, size or other specifications. In this study, we excised a mass of nasal vestibule, a site far away sun-exposure. To our knowledge, this is the first case of nasal vestibular keratoacanthoma. For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management.
Otorhinolaryngology Research Centre, Department of Otolaryngology, Head and Neck Surgery, Tehran University of Medical Sciences, Amir-A'lam Hospital, Tehran, Iran.
N
N
Yazdani
M
M
Khorsandi-Ashtiani
M
M
Rabbani-Anari
A
A
Bassam
A
A
Kouhi
D000368:Aged; D001706:Biopsy; D006801:Humans; D007636:Keratoacanthoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D009296:Nasal Cavity / Q000473:pathology*; D009668:Nose Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D012871:Skin Diseases / Q000473:pathology*; D016896:Treatment Outcome