The scientific legacy of Jacques Monod.
The operon model was the last "great" discovery of molecular biology, and a decisive event for the entrance of molecular biology into embryology. But the work of Monod was not limited to the elaboration of this model. He was one of the founders of molecular biology, in the paradigm of which biologists still work. I focus on two episodes of Monod's career--his strong opposition to Lysenkoism and the elaboration of the allosteric model--to outline the ideas and convictions of the early molecular biologists.
Département de Biologie, Centre Cavailles, Ecole normale supérieure, UMR8541, 46 rue d'Ulm, 75230 Paris, France. morange@biologie.ens.fr
Michel
M
Morange
D001419:Bacteria / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D005827:Genetics, Microbial / Q000266:history*; D049673:History, 20th Century; D006801:Humans; D008967:Molecular Biology / Q000266:history*; D009876:Operon