Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.
Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC).
Raveendran
Anabha E
AE
Organic Chemistry Division, NIIST, Thiruvananthapuram, Kerala, India.
Paul
Rony Rajan
RR
Suresh
Eringathodi
E
Nair
Vijay
V
D000098:Acetophenones / Q000737:chemistry*; D000179:Acrylates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003979:Diazonium Compounds / Q000737:chemistry; D007700:Kinetics; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008956:Models, Chemical; D013237:Stereoisomerism; D013696:Temperature
D000098:Acetophenones; D000179:Acrylates; D003979:Diazonium Compounds; C030011:carbene; C013190:phenacyl bromide; D008697:Methane