Intrauterine device or estrogen treatment after hysteroscopic uterine septum resection.
OBJECTIVE
To investigate the effects on adhesion formation and pregnancy maintenance of an intrauterine device (IUD) and/or estrogen treatment after hysteroscopic septum resection.


METHODS
After septum resection 100 women received either no treatment, or estrogens, or an IUD, or an IUD plus estrogens (n=25 per group). Most were later checked hysteroscopically for uterine cavity adhesions. All pregnancies occurring during the study period were recorded.


RESULTS
Adhesions developed in 1 of 19 (5.3%) of the untreated women, 3 of 25 (12%) of the women treated with an IUD plus estrogens, 2 of 19 (10.5%) of the women treated with an IUD only, and none of the women treated with estrogens only. None of the differences, however, were significant. Regarding pregnancy, the differences between groups were also not significant.


CONCLUSIONS
Neither IUD placement, nor estrogen treatment, nor both were found to prevent intrauterine adhesions or facilitate pregnancy after hysteroscopic uterine septum resection.
Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey. esratonguc@yahoo.com
Esra Ayşin
EA
Tonguc
Turgut
T
Var
Nafiye
N
Yilmaz
Sertac
S
Batioglu
D000328:Adult; D003131:Combined Modality Therapy; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000627:therapeutic use; D004338:Drug Combinations; D004958:Estradiol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D007434:Intrauterine Devices; D009644:Norgestrel / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D016037:Single-Blind Method; D000267:Tissue Adhesions / Q000209:etiology / Q000517:prevention & control; D014599:Uterus / Q000002:abnormalities / Q000601:surgery*; D055815:Young Adult
D003277:Contraceptives, Oral, Combined; D004338:Drug Combinations; D009644:Norgestrel; D004958:Estradiol