Intralateral hypothalamic area injection of isoproterenol and propranolol affects food and water intake in broilers.
The role played by adrenergic system in water intake, especially food intake, has long been known in mammals. In avian species, there have been many experiments exploring the effects of the adrenergic system in different sites in the central nervous system in meat- and egg-type poultry. This study was designed to examine the possible effects of intralateral hypothalamic area (ILHy) microinjections of a beta-adrenergic agonist, isoproterenol, and a beta-adrenoceptor blocker, propranolol, on food and water intake in 3-h food-deprived and 3-h water-deprived broiler cockerels. Our findings suggest that the beta-adrenergic system directly affects food especially water intake in broilers. Although isoproterenol significantly (P < or = 0.05) decreased food intake for the first 15 min, it reduced food intake during the experiment. Isoproterenol reduced water intake significantly (P < or = 0.05), which was abolished by pretreatment with propranolol. It is proposed that beta-adrenoceptors in LHy play a direct and indirect role in the regulation of food especially water intake in broiler cockerels.
Baghbanzadeh
Ali
A
Section of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, PO Box 14155-6453, Tehran, Iran. abaghban@ut.ac.ir
Hajinezhad
Mohammad Reza
MR
Shohreh
Bahram
B
Maleklou
Reza
R
D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000704:Analysis of Variance; D000818:Animals; D000831:Animals, Newborn; D002645:Chickens / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects*; D004435:Eating / Q000187:drug effects*; D005508:Food Deprivation; D007031:Hypothalamus / Q000187:drug effects* / Q000502:physiology; D007545:Isoproterenol / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D013997:Time Factors; D014868:Water Deprivation
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D011433:Propranolol; D007545:Isoproterenol