A simple, mild, and regioselective method for the benzylation of carbohydrate derivatives promoted by silver carbonate.
A simple, mild, and regioselective method has been developed for the selective benzylation and p-methoxybenzylation of carbohydrate derivatives in high yields using Ag(2)CO(3) as the promoter. Benzylation of base-labile substrates, for which other reported methods are of little use, has been performed in high yields.
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Punjab, India.
Satish
S
Malik
Vaibhav A
VA
Dixit
Prasad V
PV
Bharatam
K P Ravindranathan
KP
Kartha
D001555:Benzene Derivatives / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D002254:Carbonates / Q000494:pharmacology*; D002384:Catalysis; D008956:Models, Chemical; D015394:Molecular Structure; D018030:Silver Compounds / Q000494:pharmacology*; D013237:Stereoisomerism
D001555:Benzene Derivatives; D002241:Carbohydrates; D002254:Carbonates; D018030:Silver Compounds; C033260:silver carbonate