Effect of chlorhexidine application in a self-etching adhesive on the immediate resin-dentin bond strength.
OBJECTIVE
To investigate whether the application of chlorhexidine in a two-step self-etching adhesive has an adverse effect on the immediate resin-dentin bond strength.


METHODS
Different amounts of 20 wt% chlorhexidine digluconate were added directly to the Clearfil SE Bond primer to prepare mixtures of 4 different concentrations of chlorhexidine: 0.05 wt%, 0.1 wt%, 0.5 wt%, and 1.0 wt%. Sixteen extracted third molars were randomly divided into 4 groups. Each group corresponded to one of the 4 chlorhexidine concentrations. Each of the 16 teeth was sectioned into halves. One half was customarily bonded with Clearfil SE Bond without chlorhexidine, and the other half was bonded with Clearfil SE Bond containing different concentrations of chlorhexidine. Microtensile bond strengths were tested immediately after specimen preparation. The modes of fractures were examined under a stereomicroscope.


RESULTS
No significant difference of immediate resin-dentin bond strength was observed between the control groups and any of the experimental groups containing chlorhexidine (p > 0.05).


CONCLUSIONS
The addition of chlorhexidine to a two-step self-etching adhesive primer (Clearfil SE Bond primer) has no adverse effect on the immediate resin-dentin bond strength when the chlorhexidine concentration in the primer is lower than or equal to 1.0 wt%.
Zhou
Jianfeng
J
Department of Prosthodontics, Peking University School and Hospital of Stomatology, Nandajie Haidian District, Beijing, PR of China.
Tan
Jianguo
J
Yang
Xu
X
Cheng
Chuoyue
C
Wang
Xiaoling
X
Chen
Li
L
D000134:Acid Etching, Dental / Q000379:methods*; D000891:Anti-Infective Agents, Local / Q000737:chemistry*; D002710:Chlorhexidine / Q000737:chemistry*; D003188:Composite Resins; D001840:Dental Bonding; D003799:Dental Stress Analysis; D003804:Dentin; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D019279:Resin Cements / Q000737:chemistry*; D013718:Tensile Strength
D000891:Anti-Infective Agents, Local; C438313:Clearfil SE Bond; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D019279:Resin Cements; D002710:Chlorhexidine