[Evaluation of pain reduction upon injecting goserelin acetate using an ice pack].
LH-RH agonist is the key drug in hormonal therapy for premenopausal patients with breast cancer. It is important to reduce the pain related to injecting the LH-RH agonist, because patients must continue the medication for several years. We developed a way to reduce the pain by cooling the needle injecting site with a frozen ice pack. 18 premenopausal postoperated women filled out a questionnaire on the severity of pain upon injecting Goserelin acetate compared with the pain without this cooling method and pretreatment. We estimated the pain by a Numerical Rating Scale(NRS). The NRS scores of this cooling method revealed the pain to be significantly less than by control method(p<0. 005). This cooling method could be useful for the reduction of pain upon injecting the LH-RH agonist.
Dept. of Breast Surgical Oncology, Osaka City General Hospital.
Katsumi
K
Ikeda
Yoshinori
Y
Ogawa
Hisashi
H
Nagahara
Zhang
Z
Xiang
Katsunobu
K
Sakurai
Tatsunari
T
Fukuoka
Shinya
S
Tokunaga
Yukio
Y
Nishiguchi
D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D005260:Female; D017273:Goserelin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007053:Ice; D007267:Injections; D010146:Pain / Q000517:prevention & control*; D010147:Pain Measurement; D011795:Surveys and Questionnaires
D018931:Antineoplastic Agents, Hormonal; D007053:Ice; D017273:Goserelin