Linked metabolites: a tool for the construction of directed metabolic graphs.
Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
Easton
John M
JM
School of Electronic, Electrical and Computer Engineering, University of Birmingham, Edgbaston, Birmingham, UK.
Harris
Lisa M
LM
Viant
Mark R
MR
Peet
Andrew C
AC
Arvanitis
Theodoros N
TN
D000465:Algorithms; D003196:Computer Graphics; D003628:Database Management Systems; D006801:Humans; D008660:Metabolism; D014584:User-Computer Interface