[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].
OBJECTIVE
The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).


METHODS
Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.


RESULTS
A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.


CONCLUSIONS
This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.
Hui
Jie
J
Department of Cardiology, First Hospital Affiliated to Suzhou University, Suzhou 215006, China. huijie92@163.com
Gu
Yun-Fei
YF
Wu
Xiao-Mei
XM
Zhu
Zong-Cheng
ZC
Song
Jian-Ping
JP
Yang
Xiang-Jun
XJ
Liu
Zhi-Hua
ZH
Jiang
Ting-Bo
TB
Fagn
Zu-Xiang
ZX
Jiang
Wen-Ping
WP
D000818:Animals; D047548:Defibrillators; D004195:Disease Models, Animal; D004554:Electric Countershock; D004867:Equipment Design; D012680:Sensitivity and Specificity; D013552:Swine; D014693:Ventricular Fibrillation / Q000628:therapy