Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis.
The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5-fluorouracil, electrosurgery with curettage, cryosurgery) are effective and safe in this field, but not many can do it with excellent cosmetic results like treatment with photodynamic therapy (PDT). We have treated with this technique an old patient, whose AK was resistant to other treatments; the most interesting feature of our case comes from the esthetic effects of the PDT employing a methyl-ester of 5-aminolevulinic acid as topical photosensitizer. This kind of therapy has removed not only the lesion but also the photoaging manifestations like the wrinkles and the ugly lines, leaving a smooth skin, as we have proved with 3D-profilometry technique.
Bruscino
Nicola
N
University of Florence, Italy.
Rossi
Riccardo
R
Dindelli
Margherita
M
Ghersetich
Ilaria
I
Lotti
Torello
T
D000369:Aged, 80 and over; D000622:Aminolevulinic Acid / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control; D005260:Female; D006801:Humans; D055623:Keratosis, Actinic / Q000188:drug therapy / Q000532:radiotherapy*; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012060:Rejuvenation; D015595:Skin Aging / Q000528:radiation effects; D012878:Skin Neoplasms / Q000517:prevention & control
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid