Primary PCI for acute myocardial infarction in a patient with idiopathic thrombocytopenic purpura. A case report and review of the literature.
OBJECTIVE
The occurrence of acute myocardial infarction (AMI) in patients with idiopathic thrombocytopenic purpura (ITP) is rare, especially when the platelet count is low. Since only few case reports have been published, there are no recommendations for the management of thrombocytopenic patients with AMI. The aim of the present study is to discuss different aspects of this challenging issue and to review limited data available in the literature.


METHODS
An 80-year-old patient with ITP (platelet count 5 . 10(9)/l) is presented who developed an AMI (ST segment elevation myocardial infarction) and was successfully treated by primary percutaneous coronary intervention (PCI).


CONCLUSIONS
Considering the high bleeding risk in patients with ITP and AMI, careful balance between usual anticoagulation and antiplatelet therapy on the one hand, and efforts to raise platelet count on the other hand are needed.
Cardiac Catheterization Laboratory, Clinical Hospital Center Zemun, Belgrade University School of Medicine, Belgrade, Serbia. neskovic@hotmail.com
Aleksandar N
AN
Neskovic
Ivan
I
Stankovic
Predrag
P
Milicevic
Aleksandar
A
Aleksic
Alja
A
Vlahovic-Stipac
Branko
B
Calija
Biljana
B
Putnikovic
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D015897:Comorbidity; D017023:Coronary Angiography; D003613:Danazol / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004562:Electrocardiography; D004965:Estrogen Antagonists / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications*
D000305:Adrenal Cortex Hormones; D004965:Estrogen Antagonists; D010975:Platelet Aggregation Inhibitors; D003613:Danazol