Evaluation of an upgraded version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test for HIV-1 load quantification.
We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated.
APHP, Laboratoire de Virologie, Hopital Bichat Claude Bernard, Paris, France. florence.damond@bch.aphp.fr
F
F
Damond
V
V
Avettand-Fenoel
G
G
Collin
B
B
Roquebert
J C
JC
Plantier
A
A
Ganon
D
D
Sizmann
R
R
Babiel
J
J
Glaubitz
M L
ML
Chaix
F
F
Brun-Vezinet
D
D
Descamps
C
C
Rouzioux
D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D019562:Viral Load
D011933:Reagent Kits, Diagnostic