siRNAs: the hidden face of the small RNA world.
MicroRNAs are believed to control many physiological processes in animals. Now, two studies show that some of their presumptive functions are actually fulfilled by another class of RNAs - siRNAs.
Seitz
Hervé
H
Université de Toulouse, UPS, Laboratoire de Biologie Moléculaire Eucaryote, F-31000, France. seitz@ibcg.biotoul.fr <seitz@ibcg.biotoul.fr>
D000818:Animals; D053487:DEAD-box RNA Helicases / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D004722:Endoribonucleases / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D005260:Female; D008297:Male; D008540:Meiosis / Q000235:genetics / Q000502:physiology; D051379:Mice; D035683:MicroRNAs / Q000235:genetics / Q000502:physiology; D008954:Models, Biological; D009865:Oocytes / Q000502:physiology; D011506:Proteins / Q000235:genetics / Q000502:physiology; D034741:RNA, Small Interfering / Q000235:genetics* / Q000502:physiology*; D016601:RNA-Binding Proteins; D043244:Ribonuclease III
C474044:Dgcr8 protein, mouse; D035683:MicroRNAs; D011506:Proteins; D034741:RNA, Small Interfering; D016601:RNA-Binding Proteins; D004722:Endoribonucleases; C509781:Dicer1 protein, mouse; D043244:Ribonuclease III; D053487:DEAD-box RNA Helicases