Large cell/neuroendocrine carcinoma.
Large cell neuroendocrine tumors of the lung represent a recently reclassified subtype of lung cancer with features of both small cell and non-small cell lung cancer. We review diagnostic difficulties, typical presentations, and the natural history of this tumor. We review treatment data, and suggest that as in more common types of lung cancer, multi-modality therapy may be the most promising course of treatment.
Cancer & Blood Specialists of Nevada, 58 N. Pecos Road, Henderson, NV 89074, USA. rgollard@hotmail.com
Russell
R
Gollard
Sejal
S
Jhatakia
Max
M
Elliott
Michael
M
Kosty
D000818:Animals; D018287:Carcinoma, Large Cell / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy