Retinal vasculopathy associated with mixed connective tissue disease.
OBJECTIVE
To report an intractable case of retinal vasculopathy associated with mixed connective tissue disease (MCTD).


METHODS
Case report.


METHODS
Interventional case report.


RESULTS
A 35-year-old woman presented with decreased visual acuity and multiple retinal hemorrhages and macular edema in her right eye. She had a history of central retinal vein occlusion in the opposite eye and MCTD. Her clinical course deteriorated despite subsequent systemic and intravitreal steroid and immunosuppressant treatments. The retinal vasculopathy involved both artery and vein, causing wide retinal areas of nonperfusion. Her final visual acuity was hand motion.


CONCLUSIONS
MCTD may be associated with bilateral vasculopathy that is refractory to systemic steroid, intravitreal steroid, and immunosuppressant treatment.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
Yong-Kyu
YK
Kim
Se Joon
SJ
Woo
Yun Jong
YJ
Lee
Kyu Hyung
KH
Park
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008269:Macular Edema / Q000188:drug therapy; D008947:Mixed Connective Tissue Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D012170:Retinal Vein Occlusion / Q000473:pathology; D016896:Treatment Outcome; D014221:Triamcinolone / Q000627:therapeutic use; D014792:Visual Acuity
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D014221:Triamcinolone