Novel influenza H1N1 in pregnancy: a report of two cases.
BACKGROUND
Pregnant women are a high-risk group for morbidity and mortality from influenza. During the current pandemic of H1N1 influenza, few cases of H1N1 have been reported in pregnancy.


METHODS
We report two cases of H1N1 influenza which occurred in single institution in the course of one month. The first patient developed acute respiratory distress syndrome, required intubation, and eventually died. The second patient had influenza H1N1 that did not have any major sequela.


CONCLUSIONS
H1N1 influenza in pregnancy can be associated with severe complications. Widespread vaccination, when available, prompt diagnosis, and adequate treatment with antiviral medications when infection occurs are required.
Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USA. dmitry.fridman@gmail.com
Dmitry
D
Fridman
Oumar
O
Kuzbari
Howard
H
Minkoff
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology
D000998:Antiviral Agents