Taming the next-gen beast.
This month's Genome Watch discusses how alternative approaches to using second-generation sequencing technologies are powerful tools for the analysis of common pathogenic bacteria.
Bentley
Stephen
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Stephen Bentley is at the Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. microbes@sanger.ac.uk
D003428:Cross Infection / Q000382:microbiology; D016680:Genome, Bacterial; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D012485:Salmonella typhi / Q000235:genetics* / Q000502:physiology; D017422:Sequence Analysis, DNA / Q000379:methods*; D013203:Staphylococcal Infections / Q000382:microbiology