[Long-term clinical outcomes of patients undergoing successful or failed percutaneous coronary intervention for chronic total occlusions of coronary arteries].
OBJECTIVE
To evaluate the long-term outcomes of successful or failed revascularization in patients with chronic total occlusions (CTO).


METHODS
The clinical data of 1332 consecutive patients underwent percutaneous coronary intervention (PCI) for CTO between June 1993 and December 2006 in our hospital were analyzed. These patients were divided into two groups according to the procedural success (n = 1202) or failure (n = 130).


RESULTS
Overall success rate of procedure was 90.2% (1202/1332). The patients in CTO success group experienced a superior 10-year survival rate (76.9% vs. 64.6%, log rank P = 0.012) and a significantly higher no major adverse cardiovascular event (MACE) survival rate (41.8% vs. 27.6%, log rank P < 0.001) compared to the patients in CTO failure group. During the long-term follow-up, the proportion of patients who accepted coronary artery bypass grafting (CABG) was significantly lower in CTO success group than that in the CTO failure group (4.3% vs. 14.6%, P < 0.001).


CONCLUSIONS
Successful PCI procedure leads to increased long-term survival and MACE-free survival and the reduced need for CABG for patients with CTO lesions.
Department of Cardiology, Cardiovascular Institute, General Hospital of Shenyang Command, Shenyang 110016, China.
Xian-Hua
XH
Yi
Ya-Ling
YL
Han
Yi
Y
Li
Shou-Li
SL
Wang
Quan-Min
QM
Jing
Ying-Yan
YY
Ma
Xiao-Zeng
XZ
Wang
Bo
B
Luan
Geng
G
Wang
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001162:Arteriosclerosis Obliterans / Q000628:therapy*; D054059:Coronary Occlusion / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016896:Treatment Outcome