The role of nucleotide sugar transporters in development of eukaryotes.
The Golgi apparatus membrane of all eukaryotes has nucleotide sugar transporters which play essential roles in the glycosylation of glycoproteins, proteoglycans and glycolipids. Mutations of these transporters have broad developmental phenotypes across many species including diseases in humans and cattle.
Liu
Li
L
Department of Molecular and Cell Biology, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA.
Xu
Yu-Xin
YX
Hirschberg
Carlos B
CB
D000595:Amino Acid Sequence; D000818:Animals; D050260:Carbohydrate Metabolism; D056890:Eukaryota / Q000166:cytology / Q000502:physiology*; D006056:Golgi Apparatus / Q000378:metabolism*; D006801:Humans; D007891:Leishmania / Q000378:metabolism / Q000472:pathogenicity; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D009154:Mutation; D009711:Nucleotides / Q000378:metabolism*; D010641:Phenotype; D016415:Sequence Alignment
D026901:Membrane Transport Proteins; D009711:Nucleotides