[Epidemiological study on plasma lipid among patients with cardiovascular disease in 9 cities of the Pearl River Delta region].
OBJECTIVE
To compare the plasma lipid levels among hospitalized patients with cardiovascular diseases in 1995 and 2005 in the Pearl River delta region.


METHODS
Representative samples of 8040 patients were obtained from 16 3A hospitals in the Pearl River Delta region and 2239 patients hospitalized in 1995 and 5801 patients hospitalized in 2005 were analyzed.


RESULTS
(1) Numbers of hospitalized patients with hypertension, hypertension and coronary artery disease (CAD) or CAD risk equivalent and patients with hypertension and CAD and CAD risk equivalent were significantly increased in 2005 compared with 1995 (all P = 0.000). (2) Triglycerides (P = 0.033) and high-density lipoprotein cholesterol (HDL-C) (P = 0.000) levels from hospitalized patients were significantly higher while low-density lipoprotein cholesterol (LDL-C) level (P = 0.000) was significantly lower in 2005 than those in 1995. (3) HDL-C levels of female patients were significantly higher than those of male patients in 1995 (P = 0.045) and 2005 (P = 0.000). (4) The highest cholesterol levels were found in patients with hypertension in 1995 and 2005. LDL-C level was the highest and HDL-C level was the lowest in patients with hypertension and CAD or CAD risk equivalent in 1995. The highest LDL-C level was found in hypertension patients in 2005.


CONCLUSIONS
LDL-C level in hospitalized patients with CAD related diseases were significantly decreased in 2005 compared that in 1995 partly due to the widespread use of lipid-lowering drugs. Proportion of hospitalized patients with hypertension, hypertension with CAD or CAD risk equivalent, hypertension with CAD and CAD risk equivalent were significantly higher in 2005 compared with that in 1995.
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000453:epidemiology*; D007297:Inpatients; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D008074:Lipoproteins; C030104:lipoprotein cholesterol; D002784:Cholesterol