A remorin protein interacts with symbiotic receptors and regulates bacterial infection.
Remorin proteins have been hypothesized to play important roles during cellular signal transduction processes. Induction of some members of this multigene family has been reported during biotic interactions. However, no roles during host-bacteria interactions have been assigned to remorin proteins until now. We used root nodule symbiosis between Medicago truncatula and Sinorhizobium meliloti to study the roles of a remorin that is specifically induced during nodulation. Here we show that this oligomeric remorin protein attaches to the host plasma membrane surrounding the bacteria and controls infection and release of rhizobia into the host cytoplasm. It interacts with the core set of symbiotic receptors that are essential for perception of bacterial signaling molecules, and thus might represent a plant-specific scaffolding protein.
Lefebvre
Benoit
B
Laboratoire des Interactions Plantes Micro-organismes, Institut National de la Recherche Agronomique, Centre National de la Recherche Scientifique, 31326 Castanet Tolosan cedex, France.
Timmers
Ton
T
Mbengue
Malick
M
Moreau
Sandra
S
Hervé
Christine
C
Tóth
Katalin
K
Bittencourt-Silvestre
Joana
J
Klaus
Dörte
D
Deslandes
Laurent
L
Godiard
Laurence
L
Murray
Jeremy D
JD
Udvardi
Michael K
MK
Raffaele
Sylvain
S
Mongrand
Sebastien
S
Cullimore
Julie
J
Gamas
Pascal
P
Niebel
Andreas
A
Ott
Thomas
T
D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D017931:DNA Primers / Q000235:genetics; D046913:Medicago truncatula / Q000235:genetics / Q000382:microbiology* / Q000502:physiology*; D008969:Molecular Sequence Data; D009154:Mutation; D010750:Phosphoproteins / Q000235:genetics / Q000502:physiology*; D010940:Plant Proteins / Q000235:genetics / Q000502:physiology*; D030821:Plants, Genetically Modified; D034622:RNA Interference; D012231:Rhizobium / Q000235:genetics; D015398:Signal Transduction; D016962:Sinorhizobium meliloti / Q000502:physiology*; D013559:Symbiosis / Q000502:physiology*; D014170:Transformation, Genetic
D002352:Carrier Proteins; D017931:DNA Primers; D010750:Phosphoproteins; D010940:Plant Proteins; C103794:remorin