Preparation of potassium alkynylaryltrifluoroborates from haloaryltrifluoroborates via Sonogashira coupling reaction.
A novel series of alkyne-containing potassium organotrifluoroborates were prepared in good yields from the corresponding haloaryltrifluoroborates and various alkynes via Sonogashira coupling reaction. Also, the Suzuki-Miyaura cross-coupling reaction of alkynylaryltrifluoroborates with aryl and alkenyl bromides was achieved in the presence of 5 mol % of Pd(TPP)(4) and 3.0 equiv of Cs(2)CO(3) in aqueous 1,4-dioxane at 150 degrees C by microwave irradiation.
Kim
Dong-Su
DS
Natural Products Research Center, Korea Institute of Science and Technology, 290 Daejeon-dong, Gangneung 210-340, Korea.
Ham
Jungyeob
J
D000480:Alkynes / Q000737:chemistry*; D001881:Borates / Q000737:chemistry*; D008872:Microwaves; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011188:Potassium / Q000737:chemistry*
D000480:Alkynes; D001881:Borates; D009942:Organometallic Compounds; C098759:fluoroboric acid; D011188:Potassium