[Endocarditis due to infection by Paecilomyces variotii].
Fungal endocarditis is a cardiac complication that has been increasing throughout the world. We present a case of infective endocarditis by Paecilomyces variotii in a male patient with a prosthetic mitral valve. Successful treatment consisted of administration of amphotericin B (total dose 3670 mg) and mitral valve replacement. Only six cases have been reported previously, with a 100% mortality rate.
Sección de Cardiología, Departamento de Medicina Interna, Hospital Universitario San Vicente de Patil, Universidad de Antioquia, Medellín, Colombia. mmbt@une.net.co
Juan Manuel
JM
Senior
Clara
C
Saldarriaga
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001705:Bioprosthesis / Q000009:adverse effects*; D003131:Combined Modality Therapy; D020878:Device Removal; D004696:Endocarditis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000382:microbiology; D009181:Mycoses / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D010143:Paecilomyces / Q000302:isolation & purification*; D011183:Postoperative Complications / Q000209:etiology; D016459:Prosthesis-Related Infections / Q000382:microbiology*; D011654:Pulmonary Edema / Q000209:etiology; D012086:Reoperation; D012214:Rheumatic Heart Disease / Q000601:surgery
D000935:Antifungal Agents; D000666:Amphotericin B