C(3)-symmetric chiral trisimidazoline: design and application to organocatalyst.
C(3)-symmetric chiral trisimidazoline was designed and synthesized as a new entry of organocatalyst with the concept of constructing C(3)-symmetric molecules with three C(2)-symmetric chiral components, and the application of this novel catalyst to asymmetric conjugate addition of beta-ketoesters to nitroolefins was described.
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871 Japan.
Kenichi
K
Murai
Shunsuke
S
Fukushima
Shoko
S
Hayashi
Yusuke
Y
Takahara
Hiromichi
H
Fujioka
D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D015195:Drug Design; D004952:Esters / Q000737:chemistry; D048288:Imidazolines / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D000475:Alkenes; D004952:Esters; D048288:Imidazolines