Empyema due to a highly transmissible Pseudomonas aeruginosa strain in an adult cystic fibrosis patient.
Chronic pulmonary infection with Pseudomonas aeruginosa occurs in up to 85 % of individuals with cystic fibrosis (CF) by the time they reach adulthood, and is the major cause of morbidity and mortality: nearly all patients die from progressive respiratory failure due to repeated pulmonary exacerbations. However, despite the predilection of this organism for the lungs of CF people, infection of the pleura is much less common and is not well described in the CF population. We describe what is believed to be the first case of pleural empyema due to a particularly pathogenic transmissible strain of P. aeruginosa (the Liverpool epidemic strain) in an adult CF patient.
Mohan
Kamlesh
K
Adult Cystic Fibrosis Unit, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK.
Lakshman
Vinay
V
Adult Cystic Fibrosis Unit, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK.
Fothergill
Joanne L
JL
National Institute for Health Research Biomedical Research Centre, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK.|Division of Medical Microbiology, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK.
Ledson
Martin J
MJ
Adult Cystic Fibrosis Unit, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK.
Winstanley
Craig
C
National Institute for Health Research Biomedical Research Centre, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK.|Division of Medical Microbiology, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK.
Walshaw
Martin J
MJ
Adult Cystic Fibrosis Unit, Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK.
D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications*; D004653:Empyema / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D013902:Radiography, Thoracic; D006113:United Kingdom