A novel two-step kit for topical treatment of tinea pedis--an open study.
BACKGROUND
Tinea pedis is a common skin disease affecting most of the population during their lifetime. Topical and systemic treatments give only temporary relief.


OBJECTIVE
To evaluate the efficacy and safety of a new topical treatment for moderate-to-severe tinea pedis.


METHODS
Fifty patients suffering from tinea pedis were treated in two stages: the active stage--single use of the novel topical solution for 45 min and novel cream twice weekly for 4 weeks; the preventive stage--cream application once weekly for 10 months.


RESULTS
Forty-five patients completed the active stage and achieved 76% cure rate. The medication was well tolerated; one patient dropped from the study because of very mild irritation. No other topical or systemic side effects were noted. Another five patients were lost to follow-up during the preventive stage. The total cure rate after the preventive stage was 70%.


CONCLUSIONS
This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.
Department of Dermatology, Sheba Medical Center, Tel-Hashomer, Israel.
A
A
Shemer
M H
MH
Grunwald
B
B
Davidovici
N
N
Nathansohn
B
B
Amichai
D000287:Administration, Topical; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014008:Tinea Pedis / Q000188:drug therapy*
D000935:Antifungal Agents