[A case of advanced gastric cancer responding to S-1 chemotherapy for three weeks].
We reported a patient with advanced gastric cancer successfully treated with S-1 chemotherapy for three weeks. The patient was a 67-year-old man who had gastric cancer clinically diagnosed as cT3N1H0P0M0, stage IIIA. His treatment was supposed to be daily oral administration of 120 mg S-1 for 28 days. At 21 days, this treatment was stopped due to severe appetite loss. The histological diagnosis of the resected stomach revealed complete disappearance of cancer cells in the stomach and the regional lymph nodes. Our report suggested that S-1 may have a potent therapeutic effect in neoadjuvant chemotherapy for advanced gastric cancer.
Sakurai
Katsunobu
K
Dept. of Digestive Surgery, Osaka City General Hospital.
Yamashita
Yoshito
Y
Shimizu
Sadatoshi
S
Yoshida
Kayo
K
Fukuoka
Tatsunari
T
Xiang
Zhang
Z
Yamamoto
Satoshi
S
Yamamoto
Atsushi
A
Kanazawa
Akishige
A
Takemura
Masashi
M
Tsukamoto
Tadashi
T
Nishiguchi
Yukio
Y
Ikehara
Teruyuki
T
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid