[Retrospective analysis of 125 cases of pregnancies complicated by rheumatic heart disease].
OBJECTIVE
To investigate the impact of rheumatic heart disease on pregnancy.


METHODS
A retrospective study was conducted in 125 pregnant women with rheumatic heart disease. These cases were divided into operation (group A) and non-operation (group B), and the cardiac function, pregnancy complications, gestational weeks, delivery modes and outcomes of pregnancy were compared.


RESULTS
The cardiac function was significantly improved and pregnancy complications reduced after the cardiac operation with extended gestational weeks, showing significant differences between the two groups (P<0.05). One perinatal fetal death without maternal death occurred in group A, as compared with two maternal and two perinatal deaths in group B. Cesarean section was the primary delivery mode in these cases.


CONCLUSIONS
Surgical interventions can improve the cardiac function, reduce the pregnancy complications and improve the pregnancy outcomes in pregnant women with rheumatic heart disease. Cesarean section is the primary choice for pregnant women with prosthetic heart valve replacement.
Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. liyanqiu1977@163.com
Yan-qiu
YQ
Li
Yan-hong
YH
Yu
Jun
J
Zhou
Xun
X
Xia
D000328:Adult; D002585:Cesarean Section; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology* / Q000601:surgery; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012214:Rheumatic Heart Disease / Q000503:physiopathology* / Q000601:surgery; D055815:Young Adult