Anti-N-methyl-D-aspartate receptor encephalitis: early treatment is beneficial.
Anti-N-methyl-D-aspartate receptor antibody has been associated with a severe stereotypic form of subacute encephalitis, often found in women with ovarian teratoma. Reported here is the diagnosis of anti-N-methyl-D-aspartate receptor encephalitis in a 5-year-old girl who presented with subacute encephalopathy and movement disorder without evidence of malignancy. Early diagnosis and treatment with immune globulin and steroids resulted in near-complete recovery.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Erin H
EH
Breese
Joseph
J
Dalmau
Vanda A
VA
Lennon
Metha
M
Apiwattanakul
Deborah K
DK
Sokol
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology* / Q000378:metabolism*; D020274:Autoimmune Diseases of the Nervous System / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism; D002675:Child, Preschool; D004660:Encephalitis / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use*; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology* / Q000378:metabolism*
D000893:Anti-Inflammatory Agents; D000888:Antibodies, Anti-Idiotypic; D016194:Receptors, N-Methyl-D-Aspartate; D008775:Methylprednisolone