[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].
OBJECTIVE
The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).


METHODS
Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.


RESULTS
A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.


CONCLUSIONS
This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.
Department of Cardiology, First Hospital Affiliated to Suzhou University, Suzhou 215006, China. huijie92@163.com
Jie
J
Hui
Yun-Fei
YF
Gu
Xiao-Mei
XM
Wu
Zong-Cheng
ZC
Zhu
Jian-Ping
JP
Song
Xiang-Jun
XJ
Yang
Zhi-Hua
ZH
Liu
Ting-Bo
TB
Jiang
Zu-Xiang
ZX
Fagn
Wen-Ping
WP
Jiang
D000818:Animals; D047548:Defibrillators; D004195:Disease Models, Animal; D004554:Electric Countershock; D004867:Equipment Design; D012680:Sensitivity and Specificity; D013552:Swine; D014693:Ventricular Fibrillation / Q000628:therapy