A simple, mild, and regioselective method for the benzylation of carbohydrate derivatives promoted by silver carbonate.
A simple, mild, and regioselective method has been developed for the selective benzylation and p-methoxybenzylation of carbohydrate derivatives in high yields using Ag(2)CO(3) as the promoter. Benzylation of base-labile substrates, for which other reported methods are of little use, has been performed in high yields.
Malik
Satish
S
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Punjab, India.
Dixit
Vaibhav A
VA
Bharatam
Prasad V
PV
Kartha
K P Ravindranathan
KP
D001555:Benzene Derivatives / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D002254:Carbonates / Q000494:pharmacology*; D002384:Catalysis; D008956:Models, Chemical; D015394:Molecular Structure; D018030:Silver Compounds / Q000494:pharmacology*; D013237:Stereoisomerism
D001555:Benzene Derivatives; D002241:Carbohydrates; D002254:Carbonates; D018030:Silver Compounds; C033260:silver carbonate