Therapeutic Hotline: Topical glycopyrrolate: a successful treatment for craniofacial hyperhidrosis and eccrine hidrocystomas.
Eccrine hidrocystoma is a benign tumor derived from eccrine sudoriparous glands. Most eccrine hidrocystomas are solitary and asymptomatic lesions. Multiple hidrocystomas are unusual and have been associated with Graves' disease, Parkinson's disease, and idiopathic craniofacial hyperhidrosis. This report describes the successful treatment of multiple center facial eccrine hidrocystomas associated with craniofacial hyperhidrosis with 0.5% glycopyrrolate aqueous solution applied locally for 1 week. The present authors obtained a very significant improvement without leaving any trace of clinical examination. Multiple eccrine hidrocystomas are a rare condition and, to date, no effective treatment has been reported. Topical glycopyrrolate is a very good first-line treatment option.
University Hospital "Reina Sofía," Córdoba, Spain. glorina_81@hotmail.com
Gloria María
GM
Garnacho Saucedo
José Carlos
JC
Moreno Jiménez
Rafael
R
Jiménez Puya
Alfonso
A
Rodríguez Bujaldon
D000279:Administration, Cutaneous; D004439:Eccrine Glands / Q000473:pathology; D005142:Eyelid Neoplasms / Q000188:drug therapy*; D005260:Female; D006024:Glycopyrrolate / Q000008:administration & dosage / Q000627:therapeutic use*; D018251:Hidrocystoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D013544:Sweat Gland Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D018727:Muscarinic Antagonists; D006024:Glycopyrrolate