A non-linear three-dimensional model for quantifying microbubble dynamics.
A three-dimensional non-linear model for simulating microbubble response to acoustic insonation is presented. A 1 mum radius microbubble stimulated using positive and inverted 2.4 MHz pulses produced radius-time curves that matched (error <10%) with the experimental observation. A bound 2.3 mum radius microbubble insonated using 2.25 MHz 6 cycle pulse was observed to oscillate with max/min oscillations 45% lower than that of the free microbubble, this correlated ( approximately 10% error) with the observations of Garbin et al. [Appl. Phys. Lett. 90, 114103 (2007)]. The adherent microbubble oscillated asymmetrically in the plan view and symmetrically in the elevation view, consistent with the previous experimental results.
Department of Biomedical Engineering, University of Virginia, 415 Lane Road, Room 2127, Charlottesville, Virginia 22908, USA. avp2b@virginia.edu
Abhay V
AV
Patil
Paul
P
Reynolds
John A
JA
Hossack
D000465:Algorithms; D003198:Computer Simulation; D045423:Microbubbles; D008962:Models, Theoretical; D017711:Nonlinear Dynamics; D016011:Normal Distribution; D010507:Periodicity; D011312:Pressure; D012984:Software; D013997:Time Factors; D014465:Ultrasonics; D014732:Vibration