Molecular diagnostics for head and neck pathology.
Molecular diagnostic techniques are quickly finding a role in the detection and diagnosis of tumors, and in predicting their behavior. They may also prove useful in developing new therapeutic approaches to head and neck cancer. The surgeon working in the craniomaxillofacial region should have an understanding of these technologies, their availability in various settings, and how they affect various aspects of treatment, particularly in the detection and treatment of malignancies. This article offers an overview of recent advances in molecular diagnostic techniques, with their implications for diagnosis and management of head and neck tumors.
Department of Oral and Maxillofacial Surgery, University of Pittsburgh School of Dental Medicine, 3501 Terrace Street, Pittsburgh, PA 15261, USA.
Elizabeth
E
Bilodeau
Faizan
F
Alawi
Bernard J
BJ
Costello
Joanne L
JL
Prasad
D004273:DNA, Neoplasm / Q000032:analysis; D016503:Drug Delivery Systems; D005821:Genetic Techniques; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D013677:Medical Laboratory Science; D015336:Molecular Probe Techniques; D009363:Neoplasm Proteins / Q000032:analysis; D057089:Pathology, Molecular; D040901:Proteomics; D012334:RNA, Neoplasm / Q000032:analysis
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm