[Analysis of complications during and post interventional therapy of congenital heart disease].
OBJECTIVE
To analyze the incidence and cause of complications during and after interventional therapy for congenital heart disease (CHD).


METHODS
From April 1986 to April 2009, 388 out of 6029 patients with CHD developed complications during and post interventional therapy, another 5 patients died post procedure, clinical data from these 393 patients were retrospectively analyzed. The patients with severe functional insufficiency requiring intervention or surgery during and after interventional therapy were classified as severe complications.


RESULTS
The overall complication rate was 6.44% [7.69% post atrial septal defect occlusion, 4.20% post patent ductus arteriosus (PDA) occlusion, 1.31% post percutaneous balloon pulmonary valvuloplasty, 14.94% post ventricular septal defect occlusion, 3.13% post percutaneous closure of aortopulmonary collaterals, 30.95% post catheter embolotherapy of pulmonary arteriovenous malformations, 12.50% post transcatheter closure of coronary artery fistulae, 20.00% post transcatheter closure of ruptured sinus of Valsava aneurysm, 66.67% post percutaneous balloon aortic valvuloplasty]. The severe complication rate was 0.65%(39/6029). The procedure-related mortality rate was 0.08% (5/6029), 0.26% (2/761) post percutaneous balloon pulmonary valvuloplasty, 0.05% (1/2070) post PDA occlusion, 9.10% (1/11) post balloon atrial septostomy, 33.33% (1/3) post percutaneous balloon aortic valvuloplasty. Emergency Cardiovascular surgery rate was 0.22% (13/6029). Selective surgery was required in 0.13% (8/6029) of patients post procedure. Two patients (0.03%) received permanent pacemaker implantation.


CONCLUSIONS
The severe complications and mortality rate of interventional therapy for CHD are relative low. Post procedure follow-up is needed fro monitoring possible procedure-related complications.
Jiang
Shi-Liang
SL
Cardiac Catheterization Laboratory, Department of Radiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. jiangsl_2008@163.com
Xu
Zhong-Ying
ZY
Zhao
Shi-Hua
SH
Ling
Jian
J
Zheng
Hong
H
Zhang
Ge-Jun
GJ
Zhang
Yan
Y
Jin
Jing-Lin
JL
Lü
Bin
B
Dai
Ru-Ping
RP
Liu
Yu-Qing
YQ
Wang
Yun
Y
D006328:Cardiac Catheterization / Q000009:adverse effects*; D013504:Cardiovascular Surgical Procedures; D006330:Heart Defects, Congenital / Q000601:surgery / Q000628:therapy*; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D016896:Treatment Outcome