Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature.
Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been identified as a novel and distinctive type of primary central nervous system neoplasm. In this report, we present a case with RGNT arising from the right cerebellar hemisphere. A 30-year-old female patient complained of headache for a five-year duration. Preoperative MRI revealed a well-circumscribed, cystic-solid lesion with hypo-intensity on T1-weighted image, hyper-intensity on T2-weighted image, and significant dot-like enhancement after IV contrast. Gross total resection was achieved in this case via suboccipital retro-sigmoidal approach, and RGNT was confirmed in the final histopathological diagnosis. RGNT of the fourth ventricle is a rare, benign tumor with an excellent prognosis. Operation is recommended as the prior protocol of treatment, and the follow-up MRI is necessary to evaluate the long-term prognostic effects. Currently, only one case of progression or recurrence has been reported in the postoperative course.
Luan
ShiHai
S
Department of Neurosurgery, Huashan Hospital affiliated to Fudan University, Shanghai Neurosurgical Center, The 3rd ward, 12 Middle Wulumuqi Road, Shanghai 200040, PR China.
Zhuang
DongXiao
D
Sun
LinLin
L
Huang
Feng-Ping
FP
D000328:Adult; D002528:Cerebellar Neoplasms / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D020546:Fourth Ventricle / Q000473:pathology* / Q000601:surgery; D005910:Glioma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures; D012397:Rosette Formation; D016896:Treatment Outcome