Familial isolated primary hyperparathyroidism with double adenoma.
Familial hyperparathyroidism includes the diagnoses of multiple endocrine neoplasia type 1, type 2A, and familial isolated primary hyperparathyroidism. Familial isolated primary hyperparathyroidism is a rare, distinct form of familial primary hyperparathyroidism, mainly due to four-gland hyperplasia or single-gland adenoma. We describe our success in treating a 24-year-old woman with familial isolated primary hyperparathyroidism with resection of double adenoma, using the guide of intraoperative parathyroid hormone (PTH) monitoring. Familial isolated primary hyperparathyroidism usually presents with four-gland hyperplasia or single-gland adenoma. However, double adenoma should be considered in the differential diagnosis. Using intraoperative parathyroid hormone levels and minimal-access surgery in familial isolated primary hyperparathyroidism may be promising.
Kandil
Emad
E
Division of Endocrine and Oncological Surgery, Department of Surgery, Tulane University School of Medicine, and Tulane University Hospital, New Orleans, LA, USA. ekandil@tulane.edu
Alabbas
Haytham H
HH
Lum
Ying W
YW
Tufaro
Anthony P
AP
D000236:Adenoma / Q000150:complications / Q000235:genetics* / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000235:genetics*; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D010282:Parathyroid Neoplasms / Q000150:complications / Q000235:genetics* / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods; D010375:Pedigree; D055815:Young Adult