Skin deposition of nickel, cobalt, and chromium in production of gas turbines and space propulsion components.
Skin exposure to nickel, cobalt, and chromium may cause sensitization and allergic contact dermatitis and it is known that many alloys and platings may release significant amounts of the metals upon contact with skin. Occupational exposure to these sensitizing metals has been studied in different settings with regards to airborne dust and different biological end points, but little is known about deposition on skin from airborne dust and direct contact with materials containing the metals. In this study, skin deposition was studied in 24 workers in an industry for development and manufacturing of gas turbines and space propulsion components. The workers were employed in three departments, representing different exposure scenarios: tools sharpening of hard metal items, production of space propulsion structures, and thermal application of different metal-containing powders. A novel acid wipe sampling technique was used to sample metals from specific skin surfaces on the hands and the forehead of the workers. Total amounts of nickel, cobalt, and chromium were measured by inductively coupled plasma mass spectrometry. The result showed that nickel, cobalt, and chromium could be detected on all skin surfaces sampled. The highest level of nickel was 15 microg cm(-2) h(-1), the highest for cobalt was 4.5 microg cm(-2) h(-1), and for chromium 0.6 microg cm(-2) h(-1). The three departments had different exposures regarding the metals. The highest levels of nickel on the skin of the workers were found in the thermal applications department, cobalt in the tools sharpening department, and chromium in the space propulsion components department. In conclusion, the workers' exposure to the metals was more likely to come from direct skin contact with items, rather than from airborne dust, based on the fact that the levels of metals were much higher on the fingers than on the back side of the hands and the forehead. The skin exposure levels of nickel and cobalt detected are judged capable to induce sensitization and elicit allergic contact dermatitis.
Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden. anneli.julander@ki.se
Anneli
A
Julander
Lizbet
L
Skare
Marie
M
Mulder
Margaretha
M
Grandér
Marie
M
Vahter
Carola
C
Lidén
D000328:Adult; D000395:Air Pollutants, Occupational / Q000032:analysis*; D016902:Air Pollution, Indoor / Q000032:analysis* / Q000706:statistics & numerical data; D001359:Aviation / Q000706:statistics & numerical data; D002857:Chromium / Q000032:analysis*; D003035:Cobalt / Q000032:analysis*; D004391:Dust / Q000032:analysis; D005260:Female; D005546:Forehead; D017575:Gloves, Protective / Q000706:statistics & numerical data; D006225:Hand; D006235:Hand Disinfection; D006801:Humans; D008297:Male; D008420:Manufactured Materials; D008875:Middle Aged; D009532:Nickel / Q000032:analysis*; D016273:Occupational Exposure / Q000032:analysis* / Q000517:prevention & control / Q000706:statistics & numerical data; D018570:Risk Assessment; D012867:Skin / Q000737:chemistry*; D012882:Skin Tests
D000395:Air Pollutants, Occupational; D004391:Dust; D002857:Chromium; D003035:Cobalt; D009532:Nickel