Alternative polyadenylation blooms.
Alternative polyadenylation generates mRNAs with 3' untranscribed regions of different lengths, often affecting transcript stability. Hornyik et al., in this issue of Developmental Cell, and Liu et al. now demonstrate a role for alternative polyadenylation in gene silencing and the regulation of flowering time in Arabidopsis thaliana.
Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Emanuel
E
Rosonina
James L
JL
Manley
D020413:3' Untranslated Regions; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D035264:Flowers / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D026161:MADS Domain Proteins / Q000235:genetics / Q000378:metabolism; D008954:Models, Biological; D026723:Polyadenylation; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism*; D018749:RNA, Plant / Q000235:genetics* / Q000378:metabolism*
D020413:3' Untranslated Regions; D029681:Arabidopsis Proteins; C418902:At5g10140 protein, Arabidopsis; D026161:MADS Domain Proteins; D012333:RNA, Messenger; D018749:RNA, Plant