Isolated extramedullary relapse of acute lymphoblastic leukemia in the breast of an adolescent girl: radiologic findings and discussion.
We report a case of isolated extramedullary leukemia relapse in the breast of an adolescent girl. A 13-year-old girl with acute lymphoblastic leukemia in remission, post-chemotherapy and unrelated cord blood transplant, presented with a breast lump. US and mammography demonstrated a large hypervascular heterogeneous mass. Examination of tissue provided by US-guided core biopsy confirmed focal leukemic relapse. US is a commonly used diagnostic tool in children and adolescents with a breast mass, for both characterization and guided biopsy.
Department of Radiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. prasanna.kumar@roswellpark.org
Prasanna R G
PR
Kumar
Zachary
Z
Grossman
Lari
L
Scorza
Thaer
T
Khoury
Rahul
R
Nayyar
D000293:Adolescent; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging*; D016217:Ultrasonography, Mammary / Q000379:methods*