Cancers converge at 2-HG.
amaxmen@rockefeller.edu
Amy
A
Maxmen
D001932:Brain Neoplasms / Q000201:enzymology* / Q000235:genetics / Q000556:secondary; D005977:Glutarates / Q000378:metabolism*; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics* / Q000378:metabolism*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D017382:Reactive Oxygen Species / Q000378:metabolism
D005977:Glutarates; D017382:Reactive Oxygen Species; C019417:alpha-hydroxyglutarate; D007521:Isocitrate Dehydrogenase