[Thickness of the retinal nerve fiber layer in unilateral amblyopic patients with high myopia in children].
OBJECTIVE
To investigate the retina nerve fiber layer (RNFL) thickness in unilateral amblyopic patients with high myopia.


METHODS
Twenty-three cases (23 eyes) with unilateral high myopia amblyopia were tested by GD(X) ECC with laser polarized light scans in the posterior pole of retina, to measure the relative RNFL thickness according to papilla optical as a center, 3.2 mm as the diameter of outer ring, 2.4 mm as the diameter of inner ring. The relative RNFL thickness of high myopia amblyopia was compared with fellow eyes, normal eyes and high myopia respectively and statistics analysis.


RESULTS
TSNIT average, superior average and inferior average of RNFL in high myopia amblyopia became thinning (56.39 +/- 5.69, 68.30 +/- 10.16, 67.34 +/- 5.83), it showed statistically differences when compared with fellow eyes (t = 2.090, 2.243, 4.236) and normal eyes (t = 3.087, 1.025, 3.481) (P < 0.05). RNFL parameters were no statistically significant differences between high myopia amblyopia and simple high myopia (t = 0.872, 0.297, 0.658; P > 0.05). TSNIT average decreases with axial length in high myopia amblyopia and high myopia, there was inverse linear correlation between RNFL thickness and axial length (r = -0.462, -0.395; P < 0.05).


CONCLUSIONS
The RNFL thickness of unilateral high myopia amblyopia of children was thinner than normal, but there wasn't obvious compared with simple high myopia. The reasons for decreased best corrected vision of unilateral high myopia amblyopia in children still need further research.
Xiao
Man-Yi
MY
Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha 410011, China. xiaomanyi2000@yahoo.com.cn
Hua
Shan
S
Tang
Luo-Sheng
LS
D000293:Adolescent; D000550:Amblyopia / Q000473:pathology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000473:pathology*; D009412:Nerve Fibers / Q000473:pathology*; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology*