Allosteric antipsychotics: m4 muscarinic potentiators as novel treatments for schizophrenia.
Farrell
Martilias
M
Division of Medicinal Chemistry, Department of Pharmacology, NIMH Psychoactive Drug Screening Program, University of North Carolina Chapel Hill Medical School, Chapel Hill, NC 27759, USA.
Roth
Bryan L
BL
D000494:Allosteric Regulation / Q000187:drug effects; D000818:Animals; D014150:Antipsychotic Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D002460:Cell Line; D006801:Humans; D051379:Mice; D051381:Rats; D043588:Receptor, Muscarinic M4 / Q000187:drug effects / Q000378:metabolism*; D012559:Schizophrenia / Q000188:drug therapy*
D014150:Antipsychotic Agents; D043588:Receptor, Muscarinic M4