Improved diagnostic validity of the ADOS revised algorithms: a replication study in an independent sample.
Recently, Gotham et al. (2007) proposed revised algorithms for the Autism Diagnostic Observation Schedule (ADOS) with improved diagnostic validity. The aim of the current study was to replicate predictive validity, factor structure, and correlations with age and verbal and nonverbal IQ of the ADOS revised algorithms for Modules 1 and 2 in a large independent Dutch sample (N = 532). Results showed that the improvement of diagnostic validity was most apparent for autism, except in very young or low functioning children. Results for other autism spectrum disorders were less consistent. Overall, these findings support the use of the more homogeneous revised algorithms, with the use of similar items across developmental cells making it easier to compare ADOS scores within and between individuals.
Karakter Child and Adolescent Psychiatry University Center, Reinier Postlaan 12, 6525 GC Nijmegen, The Netherlands. i.oosterling@karakter.com
Iris
I
Oosterling
Sascha
S
Roos
Annelies
A
de Bildt
Nanda
N
Rommelse
Maretha
M
de Jonge
Janne
J
Visser
Martijn
M
Lappenschaar
Sophie
S
Swinkels
Rutger Jan
RJ
van der Gaag
Jan
J
Buitelaar
D000367:Age Factors; D000465:Algorithms; D001321:Autistic Disorder / Q000175:diagnosis*; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007360:Intelligence; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity