Glycemic and urinary volume responses in diabetic mellitus rats treated with Solanum lycocarpum.
Dietary fiber performs important functions in diabetes mellitus control and treatment. In this study, we evaluate the reduction in plasma glucose after the treatment of diabetic rats with high-fiber Solanum lycocarpum flour. We found that serum glucose, water and food intake, urine excretion, and urine sodium concentration were reduced in S. lycocarpum flour-treated diabetic rats (TDRs), compared with diabetic control rats (DCRs). In addition, TDRs did not show signs of kidney hypertrophy, unlike those in the DCR group. These results suggest that the use of S. lycocarpum flour can be an effective support in diabetes mellitus treatment.
Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória - ES - 29042-755, Brazil. ffarina@terra.com.br
Fabiane
F
Farina
Flávia Grillo
FG
Piassi
Margareth Ribeiro
MR
Moysés
Denise Mara Soares
DM
Bazzolli
Nazaré de Souza
Nde S
Bissoli
D000704:Analysis of Variance; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects*; D015992:Body Mass Index; D006332:Cardiomegaly / Q000473:pathology; D003920:Diabetes Mellitus / Q000097:blood / Q000178:diet therapy* / Q000652:urine; D004195:Disease Models, Animal; D004326:Drinking / Q000187:drug effects; D004435:Eating / Q000187:drug effects; D038321:Glycemic Index / Q000187:drug effects*; D006984:Hypertrophy / Q000473:pathology; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000652:urine; D032322:Solanum
D001786:Blood Glucose; D012964:Sodium