Measurement of retention in comprehensive two-dimensional gas chromatography using flow modulation with methane dopant.
Flow modulation of methane-doped carrier gas is used to visualize the second dimension hold-up time in GC x GC continuously throughout the run. This provides an internal reference of hold-up time and presents a straightforward means of examining retention in each dimension of GC x GC. Retention factors on similar and dissimilar column pairs are examined. Stationary phase bleed is shown to be retained by the second dimension column.
Klee
Matthew S
MS
Agilent Technologies Inc., 2850 Centerville Rd., Wilmington, DE 19808, USA. matthew_klee@agilent.com
Blumberg
Leonid M
LM
D000473:Alkanes / Q000737:chemistry; D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods*; D008697:Methane / Q000737:chemistry*; D013696:Temperature
D000473:Alkanes; D008697:Methane