[Report of four clinical cases of Hafnia alvei bacteremia in a pediatric cardiac surgery unit].
BACKGROUND
The gram-negative bacillus Hafnia alvei is the only species of the genus Hafnia, family Enterobacteriaceae. It occasionally behaves as an opportunistic pathogen in humans, causing intestinal and respiratory infection and sepsis. It rarely causes bacteremia, usually of unknown focus.


OBJECTIVE
To describe a nosocomial outbreak of four pediatric patients with bacteremia by Hafnia alvei.


METHODS
Descriptive study using clinical records of pediatric patients diagnosed with Hafnia alvei bacteremia in a pediatric cardio surgical unit, in October 2008.


RESULTS
The attack rate was 4/8 (50%), lethality rate 2/4 (50%) and mortality 2/8 (25%). The microbiological study and pulsed-field gel electrophoresis confirmed the same clonal bacterial strain.


CONCLUSIONS
The source of bacteremia was identified only in two patients and was associated with central venous catheters. The other two cases had no known infectious source. Epidemiological surveillance of emerging agents must be maintained.
Moreno
Claudia
C
Facultad de Medicina, Universidad de Chile, Santiago, Chile. clau.moreno.m@gmail.com
Troncoso
Mercedes
M
Coria De La
Paulina
P
Ledermann
Walter
W
Del Valle
Gladys
G
Nuñez
Cecilia
C
Araya
Pamela
P
Fernández
Jorge
J
Fernández
Alda
A
D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology*; D003428:Cross Infection / Q000175:diagnosis / Q000382:microbiology*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D020611:Hafnia alvei / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies