Bacteremia caused by a highly-resistant Streptococcus pneumoniae serotype 19A circulating in a daycare center.
We describe the clinical course of a previously healthy 20-month-old toddler admitted with high fever and leukocytosis. Blood culture grew Streptococcus pneumoniae serotype 19A, belonging to the ST663 clone, highly resistant to penicillin, ceftriaxone, and erythromycin. The same clone with identical antibiogram was isolated from the nasopharynx of another three of the other five healthy children attending the same daycare center as the patient. This case exemplifies the potential problems posed by highly-resistant S. pneumoniae serotype 19A, an emerging pathogen worldwide.
Shouval
Dror S
DS
Department of Pediatrics C, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tiqwa, Israel. dror_sho@netvision.net.il
Porat
Nurith
N
Dagan
Ron
R
Keller
Nathan
N
Bilavsky
Efraim
E
Sivan
Yoram
Y
Amir
Jacob
J
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D002353:Carrier State / Q000382:microbiology; D002656:Child Day Care Centers; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000635:transmission; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D007223:Infant; D007557:Israel; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000635:transmission; D012293:Rifampin / Q000008:administration & dosage; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*; D014640:Vancomycin / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D012293:Rifampin