Large cell/neuroendocrine carcinoma.
Large cell neuroendocrine tumors of the lung represent a recently reclassified subtype of lung cancer with features of both small cell and non-small cell lung cancer. We review diagnostic difficulties, typical presentations, and the natural history of this tumor. We review treatment data, and suggest that as in more common types of lung cancer, multi-modality therapy may be the most promising course of treatment.
Gollard
Russell
R
Cancer & Blood Specialists of Nevada, 58 N. Pecos Road, Henderson, NV 89074, USA. rgollard@hotmail.com
Jhatakia
Sejal
S
Elliott
Max
M
Kosty
Michael
M
D000818:Animals; D018287:Carcinoma, Large Cell / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy