Histopathological, serological, and molecular confirmation of indigenous alveolar echinococcosis cases in Mongolia.
Alveolar echinococcosis cases diagnosed histopathologically in 2002, 2006, 2007, and 2009 in Ulaanbaatar, Mongolia were reconfirmed by evaluating the cytochrome c oxidase subunit I gene of mitochondrial DNA. The most recent three cases using paraffin-embedded and ethanol-fixed specimens revealed that one was of the "Asian" haplotype, whereas two others were of the "Inner Mongolian" type. All patients were born in the western provinces of Mongolia, they never resided outside of Mongolia, and they were given a preliminary diagnosis of malignant hepatic tumor or abscess. The most recent two cases were also confirmed serologically to be active alveolar echinococcosis.
Asahikawa Medical College, Midorigaoka Higashi 2-1-1-1, Asahikawa, Japan. akiraito@asahikawa-med.ac.jp
Akira
A
Ito
Gurbadam
G
Agvaandaram
Oyun-Erdene
OE
Bat-Ochir
Batsaikhan
B
Chuluunbaatar
Nyamkhuu
N
Gonchigsenghe
Tetsuya
T
Yanagida
Yasuhito
Y
Sako
Narankhajid
N
Myadagsuren
Temuulen
T
Dorjsuren
Kazuhiro
K
Nakaya
Minoru
M
Nakao
Yuji
Y
Ishikawa
Abmed
A
Davaajav
Nyamkhuu
N
Dulmaa
D000328:Adult; D000818:Animals; D051545:Cyclooxygenase 1 / Q000235:genetics; D004444:Echinococcosis, Hepatic / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology; D004446:Echinococcus / Q000201:enzymology / Q000235:genetics; D005260:Female; D006239:Haplotypes; D006801:Humans; D008297:Male; D008986:Mongolia / Q000453:epidemiology; D055815:Young Adult
D051545:Cyclooxygenase 1