Experimental infections of Oryzomys couesi with sympatric arboviruses from Mexico.
Coues rice rat (Oryzomys couesi), a species abundant throughout Central America, was evaluated experimentally for the ability to serve as an amplifying host for three arboviruses: Patois (Bunyaviridae, Orthobunyavirus), Nepuyo (Orthobunyavirus), and Venezuelan equine encephalitis virus subtype ID (Togaviridae, Alphavirus). These three viruses have similar ecologies and are known to co-circulate in nature. Animals from all three cohorts survived infection and developed viremia with no apparent signs of illness and long-lasting antibodies. Thus, O. couesi may play a role in the general maintenance of these viruses in nature.
Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
Eleanor R
ER
Deardorff
Naomi L
NL
Forrester
Amelia P
AP
Travassos da Rosa
Jose G
JG
Estrada-Franco
Roberto
R
Navarro-Lopez
Robert B
RB
Tesh
Scott C
SC
Weaver
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001102:Arbovirus Infections / Q000276:immunology / Q000821:virology*; D001103:Arboviruses / Q000472:pathogenicity*; D006385:Hemagglutination Inhibition Tests; D008800:Mexico; D016205:Sigmodontinae
D000914:Antibodies, Viral