Two component systems in the spatial program of bacteria.
Despite being considered a relatively simple form of life, bacteria have revealed a high degree of structural organization, with the spatial destination of their components precisely regulated within the cell. Nevertheless, the primary signals that dictate differential distribution of cellular building blocks and physiological processes remain in most cases largely undisclosed. Signal transduction systems are no exception within this three-dimensional organization and two-component systems (TCS) involved in controlling cell division, differentiation, chemotaxis and virulence show specific and/or dynamic localization, engaging in the spatial program of the bacterial cell.
García Véscovi
Eleonora
E
Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET), Departamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, S2002LRK Rosario, Argentina. garciavescovi@ibr.gov.ar
Sciara
Mariela I
MI
Castelli
María E
ME
D001419:Bacteria / Q000254:growth & development / Q000378:metabolism / Q000472:pathogenicity; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002633:Chemotaxis; D015964:Gene Expression Regulation, Bacterial; D015398:Signal Transduction; D014774:Virulence
D001426:Bacterial Proteins