Primary cutaneous carcinosarcoma: dermoscopic and immunohistochemical features.
A 73-year-old man presented a 9-month history of an enlarging nodule on his right temple. Dermoscopy revealed a non-pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epithelial component and a dermal undifferentiated sarcoma, with pleomorphic spindle cells and numerous osteoclast-like giant cells. Based on immunohistochemistry findings, a diagnosis of primary cutaneous carcinosarcoma was made and the patient underwent wide local excision.
Upjohn
Edward
E
UT Southwestern Medical Center, Skin Surgery and Oncology Clinic, 5323 Harry Hines Blvd., Dallas, TX 75390, USA. eupjohn@connexus.net.au
Braue
Anna
A
Ryan
Andrew
A
D000368:Aged; D001315:Australia; D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002296:Carcinosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D046169:Dermoscopy; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010010:Osteoclasts / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery