[Acute coronary syndrome with ST segment depression on ECG: novel outlook of an old problem].
The lecture is devoted to morphological manifestations, clinical and prognostic features of acute coronary syndrome (ACS) with ST segment depressions on ECG. We have studied peculiarities of clinical course of this variant of ACS and its outcomes in 501 patients and suggested a scheme for stratification of patients in groups of risk of complicated course of ischemic heart disease. We have also studied 85 patients with ACS with ST segment depressions on ECG during anginal attack. In therapy of these patients we included drugs with potential metabolic action: trimetazidine (n=29), infusions of polarizing mixture (n=16), enalapril maleate (n=28), potassium succinate (n=12). It has been established that the application of trimetazidine improves course and prognosis of the disease.
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D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006801:Humans; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D019802:Succinic Acid / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000806:Angiotensin-Converting Enzyme Inhibitors; D014665:Vasodilator Agents; D019802:Succinic Acid