Variability of pulse oximetry measurement over 1 year in children with sickle cell disease depends on initial oxygen saturation measurement.
A prospective cohort of children with sickle cell disease (SCD) was evaluated to determine the variability of daytime pulse oximetry among three measurements over approximately 1 year. Fifty-eight participants were evaluated. Asymptomatic children with initial oxygen saturation < or = 92% had a mean range over 1 year of 4.6% (2.1-7.5%). In contrast, asymptomatic children whose oxygen saturation was >92% had a mean range of 1.9% (0-5.5%). These results suggest, changes in pulse oximetry measurement of approximately 5% may not be clinically significant in otherwise, healthy children with SCD with previous pulse oximetry < or = 92%.
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Jonathan E
JE
Mullin
Ben
B
Cooper
Sinziana
S
Seicean
Robert
R
Strunk
Carol
C
Rosen
Susan
S
Redline
James
J
Kemp
Michael R
MR
DeBaun
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood*
D010100:Oxygen