Follicular dendritic cell sarcoma of tonsil.
Follicular dendritic cell sarcoma is a very rare entity. So far only 12 cases have been reported world wide with involvement of tonsil. We present a new case of follicular dendritic cell sarcoma of the tonsil in a 52 years old woman with no evidence of neck node involvement. She had undergone diagnostic tonsillectomy due to unilateral tonsillar enlargement. The final diagnosis after histological review and immunohistochemical stains was follicular dendritic cell sarcoma. Bone scan showed no metastasis. One year follow-up after postoperative chemotherapy showed no evidence of local or regional recurrence. Follicular dendritic cell sarcoma is a rare and underdiagnosed neoplasm. It should be included in the differential diagnosis of any tonsillar mass in adults. Follicular dendritic cell markers such as SR-100, CD21 and/or CD35 are essential for the diagnosis.
Suhail
Zahid
Z
Department of ENT, Karachi Medical and Dental College and Abbasi Shaheed Hospital, Karachi. drzahidsuhail7@hotmail.com
Musani
Mohammad Ayub
MA
Afaq
Salman
S
Zafar
Abbas
A
Ahmed Ashrafi
Syed Khalid
SK
D014408:Biomarkers, Tumor / Q000378:metabolism; D020566:Dendritic Cells, Follicular / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012509:Sarcoma / Q000378:metabolism / Q000473:pathology*; D014067:Tonsillar Neoplasms / Q000378:metabolism / Q000473:pathology*
D014408:Biomarkers, Tumor