Synophrys.
BACKGROUND
Meeting of the medial eyebrows in the midline (synophrys) may serve as a cutaneous marker lesion for syndromal disorders (e.g. Cornelia de Lange syndrome).


METHODS
A 31-year-old man showed supercilia forming a single band of terminal hairs between left and right lateral orbital rim. Medical examination of the patient revealed coldness-inducable urticaria, xanthelasma formation and long eyelashes without any signs of a syndromal disorder.


CONCLUSIONS
Synophrys can be found in some syndromal disorders, but are not pathognomonic for any illness per se.
Department of Dermatology and Allergology, Allergieklinik, Davos, Switzerland. Matthias.Moehrenschlager@hgk.ch
Matthias
M
Möhrenschlager
Martin
M
Lauenstein
Johannes
J
Ring
Claudia
C
Steiner
D000328:Adult; D005138:Eyebrows / Q000473:pathology*; D006801:Humans; D008297:Male; D011379:Prognosis; D012868:Skin Abnormalities / Q000473:pathology*