Genomic selection in plant breeding: from theory to practice.
We intuitively believe that the dramatic drop in the cost of DNA marker information we have experienced should have immediate benefits in accelerating the delivery of crop varieties with improved yield, quality and biotic and abiotic stress tolerance. But these traits are complex and affected by many genes, each with small effect. Traditional marker-assisted selection has been ineffective for such traits. The introduction of genomic selection (GS), however, has shifted that paradigm. Rather than seeking to identify individual loci significantly associated with a trait, GS uses all marker data as predictors of performance and consequently delivers more accurate predictions. Selection can be based on GS predictions, potentially leading to more rapid and lower cost gains from breeding. The objectives of this article are to review essential aspects of GS and summarize the important take-home messages from recent theoretical, simulation and empirical studies. We then look forward and consider research needs surrounding methodological questions and the implications of GS for long-term selection.
Jannink
Jean-Luc
JL
USDA-ARS, R.W. Holley Center for Agriculture and Health, Department of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA. jeanluc.jannink@ars.usda.gov
Lorenz
Aaron J
AJ
Iwata
Hiroyoshi
H
D001947:Breeding / Q000379:methods*; D003198:Computer Simulation; D023281:Genomics / Q000379:methods*; D010944:Plants / Q000235:genetics*; D012641:Selection, Genetic