Gene therapy activates EVI1, destabilizes chromosomes.
Cynthia E
CE
Dunbar
Andre
A
Larochelle
D000818:Animals; D043171:Chromosomal Instability; D002877:Chromosomes, Human; D004268:DNA-Binding Proteins / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics*; D015316:Genetic Therapy; D005822:Genetic Vectors / Q000009:adverse effects*; D006801:Humans; D000074008:MDS1 and EVI1 Complex Locus Protein; D051379:Mice; D016513:Mice, SCID; D011519:Proto-Oncogenes / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*
D004268:DNA-Binding Proteins; D000074008:MDS1 and EVI1 Complex Locus Protein; C063575:MECOM protein, human; D014157:Transcription Factors