Learning to see: patterned visual activity and the development of visual function.
To successfully interact with their environments, developing organisms need to correctly process sensory information and generate motor outputs appropriate to their size and structure. Patterned sensory experience has long been known to induce various forms of developmental plasticity that ultimately shape mature neural circuits. These same types of plasticity also allow developing organisms to respond appropriately to the external world by dynamically adapting neural circuit function to ongoing changes in brain circuitry and sensory input. Recent work on the visual systems of frogs and fish has provided an unprecedented view into how visual experience dynamically affects circuit function at many levels, ranging from gene expression to network function, ultimately leading to system-wide functional adaptations.
Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada. edward.ruthazer@mcgill.ca
Edward S
ES
Ruthazer
Carlos D
CD
Aizenman
D000818:Animals; D009415:Nerve Net / Q000254:growth & development / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D014785:Vision, Ocular / Q000502:physiology*; D014795:Visual Pathways / Q000254:growth & development / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology