Detection of enlarged yolk sac on early ultrasound is associated with adverse pregnancy outcomes.
Pregnancies with mean yolk sac diameter>or=5 mm on early ultrasound require monitoring and counseling about a threefold increased risk for first-trimester loss independent of maternal risk factors such as age, body mass index, polycystic ovary syndrome, smoking, and diabetes. In addition, our study shows for the first time that enlarged yolk sac diameter may be associated with an increased risk of preterm delivery.
Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa.
Danielle M
DM
Berdahl
Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa.
Jill
J
Blaine
Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa.
Bradley
B
Van Voorhis
Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylavnia. Electronic address: ADokras@obgyn.upenn.edu.
Anuja
A
Dokras
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D009929:Organ Size; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D018873:Pregnancy Rate; D011261:Pregnancy Trimester, First; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal; D015017:Yolk Sac / Q000002:abnormalities* / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D055815:Young Adult