Increasing incidence of community-associated atypical Clostridium difficile disease in children.
Forty-one children with a variety of gastrointestinal complaints were diagnosed with Clostridium difficile infections as part of a routine screen over 3 years. The infection had not been suspected prior to the screen. Each child responded to treatment with metronidazole with resolution of their symptoms. These data suggest that community-associated C difficile is increasing and may produce atypical disease and lead to misdiagnosis.
Baker
Susan S
SS
University at Buffalo, The State University of New York, School of Medicine and Biomedical Sciences, and Women and Children's Hospital of Buffalo, Buffalo, NY, USA.
Faden
Howard
H
Sayej
Wael
W
Patel
Raza
R
Baker
Robert D
RD
D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D003113:Colonoscopy / Q000379:methods; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000453:epidemiology*; D003937:Diagnosis, Differential; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening / Q000379:methods; D008795:Metronidazole / Q000627:therapeutic use; D012189:Retrospective Studies; D018570:Risk Assessment; D014481:United States / Q000453:epidemiology
D008795:Metronidazole