Histopathological, serological, and molecular confirmation of indigenous alveolar echinococcosis cases in Mongolia.
Alveolar echinococcosis cases diagnosed histopathologically in 2002, 2006, 2007, and 2009 in Ulaanbaatar, Mongolia were reconfirmed by evaluating the cytochrome c oxidase subunit I gene of mitochondrial DNA. The most recent three cases using paraffin-embedded and ethanol-fixed specimens revealed that one was of the "Asian" haplotype, whereas two others were of the "Inner Mongolian" type. All patients were born in the western provinces of Mongolia, they never resided outside of Mongolia, and they were given a preliminary diagnosis of malignant hepatic tumor or abscess. The most recent two cases were also confirmed serologically to be active alveolar echinococcosis.
Ito
Akira
A
Asahikawa Medical College, Midorigaoka Higashi 2-1-1-1, Asahikawa, Japan. akiraito@asahikawa-med.ac.jp
Agvaandaram
Gurbadam
G
Bat-Ochir
Oyun-Erdene
OE
Chuluunbaatar
Batsaikhan
B
Gonchigsenghe
Nyamkhuu
N
Yanagida
Tetsuya
T
Sako
Yasuhito
Y
Myadagsuren
Narankhajid
N
Dorjsuren
Temuulen
T
Nakaya
Kazuhiro
K
Nakao
Minoru
M
Ishikawa
Yuji
Y
Davaajav
Abmed
A
Dulmaa
Nyamkhuu
N
D000328:Adult; D000818:Animals; D051545:Cyclooxygenase 1 / Q000235:genetics; D004444:Echinococcosis, Hepatic / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology; D004446:Echinococcus / Q000201:enzymology / Q000235:genetics; D005260:Female; D006239:Haplotypes; D006801:Humans; D008297:Male; D008986:Mongolia / Q000453:epidemiology; D055815:Young Adult
D051545:Cyclooxygenase 1