Two-component signaling circuit structure and properties.
Various modeling and experimental studies have analyzed the reactions, interconnections, and motifs in two-component systems, with an eye toward understanding their physiological implications and the differences between alternative designs. Examples where recent progress has been made include aspects of autoregulation, signal integration in branched pathways, cross-talk suppression, and cross-regulation via connector proteins.
Goulian
Mark
M
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA. goulian@sas.upenn.edu
D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D010744:Phosphoric Monoester Hydrolases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D015398:Signal Transduction; D013171:Spores, Bacterial / Q000502:physiology
D001426:Bacterial Proteins; D010744:Phosphoric Monoester Hydrolases