The role of nucleotide sugar transporters in development of eukaryotes.
The Golgi apparatus membrane of all eukaryotes has nucleotide sugar transporters which play essential roles in the glycosylation of glycoproteins, proteoglycans and glycolipids. Mutations of these transporters have broad developmental phenotypes across many species including diseases in humans and cattle.
Department of Molecular and Cell Biology, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA.
Li
L
Liu
Yu-Xin
YX
Xu
Carlos B
CB
Hirschberg
D000595:Amino Acid Sequence; D000818:Animals; D050260:Carbohydrate Metabolism; D056890:Eukaryota / Q000166:cytology / Q000502:physiology*; D006056:Golgi Apparatus / Q000378:metabolism*; D006801:Humans; D007891:Leishmania / Q000378:metabolism / Q000472:pathogenicity; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D009154:Mutation; D009711:Nucleotides / Q000378:metabolism*; D010641:Phenotype; D016415:Sequence Alignment
D026901:Membrane Transport Proteins; D009711:Nucleotides