Linked metabolites: a tool for the construction of directed metabolic graphs.
Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
School of Electronic, Electrical and Computer Engineering, University of Birmingham, Edgbaston, Birmingham, UK.
John M
JM
Easton
Lisa M
LM
Harris
Mark R
MR
Viant
Andrew C
AC
Peet
Theodoros N
TN
Arvanitis
D000465:Algorithms; D003196:Computer Graphics; D003628:Database Management Systems; D006801:Humans; D008660:Metabolism; D014584:User-Computer Interface