Eleven-year retrospective survey of candidaemia in a university hospital in southwestern Greece.
The aim of this study was to investigate the isolation and distribution rate of Candida spp. in blood cultures and evaluate antifungal susceptibility during an 11-year period (1998–2008) at a tertiary-care hospital. The causative species were as follows: Candida albicans, 163 strains (64%); Candida parapsilosis, 35 strains (13.7%); Candida glabrata, 25 strains (9.8%); Candida tropicalis, 19 strains (7.4%); and other Candida spp., 13 strains (5.1%). Candidaemia is predominantly caused by C. albicans. C. parapsilosis is the most common non-albicans Candida isolated in neonatal intensive-care units. All Candida isolates remain susceptible to amphotericin B, whereas the highest degree of resistance was observed for azoles.
University of Patras, School of Medicine, Department of Microbiology, Patras, Greece.
A
A
Spiliopoulou
S
S
Vamvakopoulou
C
C
Bartzavali
G
G
Dimitracopoulos
E D
ED
Anastassiou
M
M
Christofidou
D000935:Antifungal Agents / Q000494:pharmacology; D001769:Blood / Q000382:microbiology; D002175:Candida / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification; D058387:Candidemia / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D006115:Greece / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies
D000935:Antifungal Agents