[Pancytopenia after methotrexate treatment].
The use of methotrexate is associated with the risk of numerous, sometimes life-threatening, side effects. We describe a 76-year-old female patient treated with methotrexate (MTX) due to vertebral joint disease of unknown etiology. During the outpatient therapy, which was not conformed to doctor's recommendations, acute liver failure and symptoms of bone marrow damage developed. Despite intensive hospital treatment, the patient died.
Katedra i Klinika Chorób Wewnetrznych Uniwersytetu Medycznego w Lublinie, Samodzielny Szpital Kliniczny Nr 1 w Lublinie.
Krzysztof
K
Zak
Andrzej
A
Prystupa
Andrzej
A
Dybała
Wojciech
W
Myśliński
Jerzy
J
Mosiewicz
D000368:Aged; D001855:Bone Marrow Diseases / Q000139:chemically induced; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017093:Liver Failure / Q000139:chemically induced; D008727:Methotrexate / Q000009:adverse effects*; D010198:Pancytopenia / Q000139:chemically induced*; D013122:Spinal Diseases / Q000188:drug therapy
D008727:Methotrexate