Synthesis of thia-analogous indirubin N-Glycosides and their influence on melanoma cell growth and apoptosis.
Kunz
Manfred
M
Comprehensive Center for Inflammation Medicine, University of Schleswig-Holstein, Campus Lübeck, 23562 Lübeck, Germany.
Driller
Katrin M
KM
Hein
Martin
M
Libnow
Stephanie
S
Hohensee
Ina
I
Ramer
Robert
R
Hinz
Burkhard
B
Berger
Anja
A
Eberle
Jürgen
J
Langer
Peter
P
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D017209:Apoptosis; D045744:Cell Line, Tumor; D006027:Glycosides / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D007211:Indoles / Q000737:chemistry; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D058570:TOR Serine-Threonine Kinases
D000970:Antineoplastic Agents; D006027:Glycosides; D007211:Indoles; D047908:Intracellular Signaling Peptides and Proteins; D019869:Phosphatidylinositol 3-Kinases; D017346:Protein Serine-Threonine Kinases; D058570:TOR Serine-Threonine Kinases; C546842:MTOR protein, human; C027185:indirubin