Grade IV fetal intracranial hemorrhage with good cognitive function.
Fewer than 200 cases of prenatally diagnosed magnetic resonance imaging-confirmed fetal intracranial hemorrhage have been reported. Children surviving grade IV fetal intracranial hemorrhage usually manifest severe impairments, including mental retardation. We report on a child with a grade IV intracranial hemorrhage diagnosed by in utero ultrasound at 28 weeks of gestation, and confirmed by fetal magnetic resonance imaging at 29 weeks of gestation. At age 27 months, she has a ventriculoperitoneal shunt and exhibits hemiplegic cerebral palsy, but without seizures, and with normal cognitive function and excellent verbal ability. We discuss how perinatal care may have contributed to her good outcome.
Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Erica T
ET
Ting
Meredith R
MR
Golomb
D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D002585:Cesarean Section; D003071:Cognition / Q000502:physiology*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005865:Gestational Age; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012720:Severity of Illness Index; D017287:Ventriculoperitoneal Shunt