Neonatal renal vein thrombosis and prothrombotic risk.
A case of extensive deep venous thrombosis in a four a day old infant was presented. Unusually this patient was shown to be heterozygous for three thrombophilia genes; Factor V Leiden, prothrombin and antithrombin gene mutations, the latter being novel.


CONCLUSIONS
There are no randomized controlled trials to guide management in deep venous thrombosis in the newborn but knowledge of the prothrombotic risk factors may help direct treatment.
Harris
S L
SL
Neonatal Unit, Christchurch Women's Hospital, Christchurch, New Zealand.
Smith
M P
MP
Laurie
A
A
Darlow
B A
BA
D006801:Humans; D007231:Infant, Newborn; D009154:Mutation; D011516:Prothrombin / Q000235:genetics*; D012082:Renal Veins / Q000000981:diagnostic imaging*; D012307:Risk Factors; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000235:genetics
D011516:Prothrombin