Taking quinazoline as a general support-Nog to design potent and selective kinase inhibitors: application to FMS-like tyrosine kinase 3.
Li
Wei-Wei
WW
State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, No 1, Keyuan Si Road, High Tech Park, Chengdu 610041, China.
Chen
Jin-Juan
JJ
Zheng
Ren-Lin
RL
Zhang
Wen-Qin
WQ
Cao
Zhi-Xing
ZX
Yang
Ling-Ling
LL
Qing
Xiao-Yu
XY
Zhou
Liang-Xue
LX
Yang
Li
L
Yu
Luo-Ding
LD
Chen
Li-Juan
LJ
Wei
Yu-Quan
YQ
Yang
Sheng-Yong
SY
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001665:Binding Sites; D003198:Computer Simulation; D015195:Drug Design; D006801:Humans; D047428:Protein Kinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D051941:fms-Like Tyrosine Kinase 3 / Q000037:antagonists & inhibitors* / Q000378:metabolism
D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D051941:fms-Like Tyrosine Kinase 3