Increasing incidence of community-associated atypical Clostridium difficile disease in children.
Forty-one children with a variety of gastrointestinal complaints were diagnosed with Clostridium difficile infections as part of a routine screen over 3 years. The infection had not been suspected prior to the screen. Each child responded to treatment with metronidazole with resolution of their symptoms. These data suggest that community-associated C difficile is increasing and may produce atypical disease and lead to misdiagnosis.
University at Buffalo, The State University of New York, School of Medicine and Biomedical Sciences, and Women and Children's Hospital of Buffalo, Buffalo, NY, USA.
Susan S
SS
Baker
Howard
H
Faden
Wael
W
Sayej
Raza
R
Patel
Robert D
RD
Baker
D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D003113:Colonoscopy / Q000379:methods; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000453:epidemiology*; D003937:Diagnosis, Differential; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening / Q000379:methods; D008795:Metronidazole / Q000627:therapeutic use; D012189:Retrospective Studies; D018570:Risk Assessment; D014481:United States / Q000453:epidemiology
D008795:Metronidazole