Ligand-free copper(I)-catalysed intramolecular direct C-H functionalization of azoles.
The first examples of copper-catalysed intramolecular direct C-arylation of azaheterocycles for the synthesis of complex heterofused compounds is presented, featuring an unprecedented arylation via C-H activation of 9H-purine and 4-azabenzimidazole.
Barbero
Nekane
N
Kimika Organikoa II Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, PO Box 644, 48080, Bilbao, Spain.
Sanmartin
Raul
R
Domínguez
Esther
E