[A case of advanced gastric cancer responding to S-1 chemotherapy for three weeks].
We reported a patient with advanced gastric cancer successfully treated with S-1 chemotherapy for three weeks. The patient was a 67-year-old man who had gastric cancer clinically diagnosed as cT3N1H0P0M0, stage IIIA. His treatment was supposed to be daily oral administration of 120 mg S-1 for 28 days. At 21 days, this treatment was stopped due to severe appetite loss. The histological diagnosis of the resected stomach revealed complete disappearance of cancer cells in the stomach and the regional lymph nodes. Our report suggested that S-1 may have a potent therapeutic effect in neoadjuvant chemotherapy for advanced gastric cancer.
Dept. of Digestive Surgery, Osaka City General Hospital.
Katsunobu
K
Sakurai
Yoshito
Y
Yamashita
Sadatoshi
S
Shimizu
Kayo
K
Yoshida
Tatsunari
T
Fukuoka
Zhang
Z
Xiang
Satoshi
S
Yamamoto
Atsushi
A
Yamamoto
Akishige
A
Kanazawa
Masashi
M
Takemura
Tadashi
T
Tsukamoto
Yukio
Y
Nishiguchi
Teruyuki
T
Ikehara
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid