Two unusual cases of severe soft tissue infection caused by Streptococcus dysgalactiae subsp. equisimilis.
We present two cases of invasive infection caused by Streptococcus dysgalactiae subsp. equisimilis, one that showed rapidly developing necrotizing fasciitis in a previously healthy man and one that showed severe cellulitis and septic shock even though the bacterium possessed a mutated emm gene, predicted to encode a truncated M protein.
Kittang
Bård Reiakvam
BR
Institute of Medicine, University of Bergen, 5021 Bergen, Norway. brki@helse-bergen.no
Langeland
Nina
N
Skrede
Steinar
S
Mylvaganam
Haima
H
D000595:Amino Acid Sequence; D000942:Antigens, Bacterial / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D002481:Cellulitis / Q000150:complications / Q000382:microbiology; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D019115:Fasciitis, Necrotizing / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009154:Mutation; D017422:Sequence Analysis, DNA; D017384:Sequence Deletion; D012772:Shock, Septic / Q000382:microbiology; D018461:Soft Tissue Infections / Q000382:microbiology*; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013291:Streptococcus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D037521:Virulence Factors / Q000235:genetics
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D004269:DNA, Bacterial; D037521:Virulence Factors; C014689:streptococcal M protein