A facile and mild synthesis of enamides using a gold-catalyzed nucleophilic addition to allenamides.
A mild and facile synthesis of enamides has been developed, based on nucleophilic addition of electron-rich aromatic and heteroaromatics to an allenamide unit catalyzed by a gold salt. Yields for the transformation were 29-98%.
Department of Chemistry, Loughborough University, Leicestershire LE11 3TU, UK. M.C.Kimber@lboro.ac.uk
Marc C
MC
Kimber