[Clinical evaluation of oral midazolam sedation for dental treatment in children].
OBJECTIVE
To assess the safety, effectiveness and acceptability of oral midazolam sedation for dental treatment in children.


METHODS
Twenty-three health children aged 4 to 14 (ASA I), who were classified as 4 or 5 by modified Venham's clinic anxiety and cooperative behavior rating scale, referred for dental treatment were included in the study. Each child was treated under sedation with oral midazolam (0.15-0.70 mg/kg), and totally 45 sedations were conducted. At each visit, heart rate, arterial oxygen saturation, respiration rate, sedation and behavioral scores were recorded. The level of acceptance and satisfaction of the patients and their guardians were recorded after the treatment.


RESULTS
Among the 23 children, 19 were boys and 4 were girls with mean age of 6.2 years old. In all the 45 treatments, the heart rate, respiratory rate and arterial oxygen saturation levels were within acceptable clinical limits. Forty planned treatments were completed satisfactorily. Oral sedation was ineffective in 3 children, and they were treated under general anesthesia. Only 2 guardians refused to have oral midazolam sedation again. Six of seven children who had regular dental check-up could be treated under normal condition.


CONCLUSIONS
Oral midazolam (0.15-0.70 mg/kg) could be a safe and acceptable approach of sedation for pediatric dental patients.
Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Bin
B
Xia
Ke-ying
KY
Liu
Chun-li
CL
Wang
Li-jun
LJ
Sun
Li-hong
LH
Ge
D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods*; D003442:Crowns; D003731:Dental Caries / Q000628:therapy*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D017060:Patient Satisfaction; D012119:Respiration / Q000187:drug effects; D014081:Tooth Extraction
D006993:Hypnotics and Sedatives; D008874:Midazolam