[Biological activity of metabolites of the herb Kalanchoe diagremontania (Hamet de la Bbathie) Jacobs et Perr].
In this study we investigated the hemolytic, antimicrobial, and phytoregulatory activity of various classes of lipids (triacylglycerols, free fatty acids (FFA), the glyceroglycolipids monogalactosyl diacylglycerol (MGDG), sulfoquinovosyl diacylglycerol (SQDG)), sterols, all of them were obtained from the medical herb Kalanchoe diagremontiana, and also pigments, phenolic compounds (FC), polysaccharides, and ethanol extract (EE) of the herbal. It was established that EE, FC, FFA, and sterols display pH-dependent membranothropic activity. FFA showed antimicrobial activity and stimulated growth of buckwheat stalk sprouts. K. diagremontiana glyceroglycolopids did not display expressed biological activity. Caroteniods displayed pH-independent membranothopic action and antibacterial activity. Chlorophylls displayed antimicrobial action, but did not influence erythrocytes and buckwheat sprouts. Polysaccharides acted against the microorganisms Safale S-04, Candida albicans, Fusarium oxysperum and buckwheat sprouts.
Anisimov
M M
MM
Gerasimenko
N I
NI
Chaĭkina
E L
EL
Serebriakov
Iu M
IuM
D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D004912:Erythrocytes / Q000378:metabolism; D005658:Fungi / Q000254:growth & development; D053878:Hemolytic Agents / Q000737:chemistry / Q000494:pharmacology; D031962:Kalanchoe / Q000737:chemistry*; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D010937:Plant Growth Regulators / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
D000890:Anti-Infective Agents; D053878:Hemolytic Agents; D010936:Plant Extracts; D010937:Plant Growth Regulators