Improvement of the microstructure and mechanical properties of bioceramic scaffolds using electrohydrodynamic spraying with template modification.
Porous scaffolds play a key role in tissue engineering (TE) approaches and new processing methods and materials are constantly being developed to cater for the wide range of specifications and requirements. Electrospraying is a relatively new processing method used for producing open-pore scaffolds. In this work, the electrospraying technique was manipulated to make the process more efficient, and the effect of spraying time on the pore size and strut thickness of zirconia scaffolds was explored. Scaffolds of adequate pore size and interconnectivity, with an average compressive strength of approximately 7.5 MPa, by electrospraying for only 10 min are reported. The effect of modifying the sacrificial template on the microstructure and mechanical properties of the sintered scaffolds was also investigated. A combination of template surface hydroxylation and improved conductivity produced a thicker ceramic coating, leading to enhanced mechanical properties.
Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK. a.muthutantri@yahoo.co.uk
Anushini I
AI
Muthutantri
Mohan J
MJ
Edirisinghe
Aldo R
AR
Boccaccini
D032701:Biomimetics; D001842:Bone and Bones / Q000502:physiology; D002516:Ceramics / Q000737:chemistry*; D002616:Chemical Engineering; D019245:Compressive Strength; D055595:Mechanical Phenomena; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D013499:Surface Properties; D013997:Time Factors; D054457:Tissue Scaffolds / Q000737:chemistry*; D015040:Zirconium / Q000737:chemistry
D011108:Polymers; D015040:Zirconium; C028541:zirconium oxide