Orbital recurrence of B-progenitor acute lymphoblastic leukemia in a child.
Orbital mass is an exceedingly rare presentation of acute lymphoblastic leukemia. This report describes a 12-year-old boy with recurrent orbital pre-B-cell acute lymphoblastic leukemia and reviews the literature on the incidence, presentation, prognosis, and management of orbital tumors in acute lymphoblastic leukemia. Early diagnosis and treatment of orbital acute lymphoblastic leukemia with a multidisciplinary approach is essential to minimize or prevent deterioration of vision and optimize clinical outcomes.
Departments of Pohthalmology, Stanford University School of Medicine, Stanford, CA, USA.
Eleonora M
EM
Lad
Atul
A
Jain
Shivanand P
SP
Lad
Richard C
RC
Lin
Deborah M
DM
Alcorn
Darius M
DM
Moshfeghi
D000208:Acute Disease; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002648:Child; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000628:therapy; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000628:therapy; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000628:therapy