Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma.
BACKGROUND
The association between gastric and pancreatic carcinoma is a relatively rare condition. In gastric carcinoma patients, the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics. Gastric cancer associated with pancreatic cancer is uncommon.


METHODS
We report a case of a 73-year-old patient hospitalized for vomiting and weight loss. Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum. Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3 X 1.7 cm) in the uncinate portion of the pancreas.


RESULTS
The patient underwent pancreaticoduodenectomy according to Whipple regional type I Fortner. Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.


CONCLUSIONS
Long survival is rare in patients with associated gastric and pancreatic cancer. Surgical resection remains the only potentially curative treatment.
Muroni
Mirko
M
Department of General Surgery, La Sapienza University of Rome, St. Andrea Hospital, viale Gino Cervi 53 L, 00139, Rome, Italy. mirkomuroni@libero.it
D'Angelo
Francesco
F
Pezzatini
Massimo
M
Sebastiani
Simone
S
Noto
Samantha
S
Pilozzi
Emanuela
E
Ramacciato
Giovanni
G
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome