[Chemotherapy-naïve advanced malignant fibrohistiocytoma presenting IVC syndrome case report].
The case was a 77-year-old male with swelling of his right leg. Physical examination revealed an ill-defined mass at RLQ. Computed tomography (CT) and 3 dimensional CT showed an 8-cm tumor on the IVC, partially replacing iliac vessels and invading the psoas muscle. A diagnosis of malignant fibrohistiocytoma was made by pathological examination of biopsied specimens at exploratory laparotomy. Five courses of combination chemotherapy of ifosfamide (IFM) and doxorubicin (DXR) resulted in PR. Edema of the lower leg and hydronephrosis were both alleviated. Another 5 courses of chemotherapy with epirubicin and IFM were added. PR lasted 2 years, though the patient succumbed to the disease in 2 years and 8 months.
Dept. of Surgery, Shonantobu General Hospital.
Yuhi
Y
Yamamoto
Mio
M
Goto
Takahide
T
Okamoto
Ichiro
I
Tomita
Akihiro
A
Murayama
Masayuki
M
Sawa
Yoshikazu
Y
Noguchi
Yoshikazu
Y
Hoshikawa
Akio
A
Shimizu
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D051677:Histiocytoma, Malignant Fibrous / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009367:Neoplasm Staging; D013479:Superior Vena Cava Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000473:pathology*
D004317:Doxorubicin; D007069:Ifosfamide