Bronchoscopic balloon dilatation of tracheobronchial stenosis: long-term follow-up.
OBJECTIVE
Bronchoscopic balloon dilatation (BBD) has become a valuable tool in the treatment of tracheobronchial stenosis (TBS). The objective of this study was to assess the short- and long-term effects of BBD.


METHODS
A retrospective study that included all patients with confirmed, symptomatic stenosis, who underwent BBD between 2002 and 2008. A total of 92 BBD procedures were performed in 35 patients at our institute. Lung function studies were recorded for all patients before, immediately after and 1 month following the BBD. Long-term follow-up was for a mean of 33+/-4 months.


RESULTS
All patients had initial success, including increased airway dimensions and symptom relief. No complications were noted related to BBD. Forced expiratory volume after one second (FEV(1)) was significantly increased after BBD (10.5%, p=0.03). These effects persisted for at least 1 month. Long-term follow-up, however, demonstrated the need for stent placement in 25 of 35 patients (71%), 210+/-91 days after BBD. Ten of 35 patients died 456+/-119 days after BBD due to progression of primary disease; all deaths were unrelated to the BBD procedures.


CONCLUSIONS
BBD is a safe method that offers immediate symptomatic relief in both tracheal and bronchial stenosis. However, BBD is a temporary measure, as many patients will require definitive or additional treatment with laser or stent placement.
Shitrit
David
D
Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. davids3@clalit.org.il
Kuchuk
Michael
M
Zismanov
Victoria
V
Rahman
Nader Abdel
NA
Amital
Anat
A
Kramer
Mordechai R
MR
D000328:Adult; D000368:Aged; D001982:Bronchial Diseases / Q000503:physiopathology / Q000628:therapy*; D001999:Bronchoscopy; D002404:Catheterization / Q000379:methods*; D003251:Constriction, Pathologic / Q000503:physiopathology / Q000628:therapy; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D014135:Tracheal Stenosis / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D014797:Vital Capacity