DBH2H: vertebrate head-to-head gene pairs annotated at genomic and post-genomic levels.
DBH2H collects head-to-head (h2h) gene pairs identified from human, mouse, rat, chicken and fugu genomes, and distinguishes the ortholog mapping relationship among them. The gene pairs in DBH2H are annotated with sequential features including single nucleotide polymorphisms, CpG islands and transcription factor binding sites, as well as functional terms and genetic disorders. In addition, the expression correlation information based on 117 microarray datasets is included. By providing user-friendly access to these data, DBH2H represents a valuable resource for further analyses of this important gene arrangement in terms of transcriptional regulation mechanisms, evolutionary conservation, disease relevance, etc.Database URL:http://lifecenter.sgst.cn/h2h/
Yu
Hui
H
Bioinformatics Center, Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai Center for Bioinformation Technology, Shanghai 200235 and College of Life Science and Technology, Tongji University, Shanghai 200092, China.
Yu
Fu-Dong
FD
Zhang
Guo-Qing
GQ
Shen
Xiang
X
Chen
Yun-Qin
YQ
Li
Yuan-Yuan
YY
Li
Yi-Xue
YX