A novel two-step kit for topical treatment of tinea pedis--an open study.
BACKGROUND
Tinea pedis is a common skin disease affecting most of the population during their lifetime. Topical and systemic treatments give only temporary relief.


OBJECTIVE
To evaluate the efficacy and safety of a new topical treatment for moderate-to-severe tinea pedis.


METHODS
Fifty patients suffering from tinea pedis were treated in two stages: the active stage--single use of the novel topical solution for 45 min and novel cream twice weekly for 4 weeks; the preventive stage--cream application once weekly for 10 months.


RESULTS
Forty-five patients completed the active stage and achieved 76% cure rate. The medication was well tolerated; one patient dropped from the study because of very mild irritation. No other topical or systemic side effects were noted. Another five patients were lost to follow-up during the preventive stage. The total cure rate after the preventive stage was 70%.


CONCLUSIONS
This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.
Shemer
A
A
Department of Dermatology, Sheba Medical Center, Tel-Hashomer, Israel.
Grunwald
M H
MH
Davidovici
B
B
Nathansohn
N
N
Amichai
B
B
D000287:Administration, Topical; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014008:Tinea Pedis / Q000188:drug therapy*
D000935:Antifungal Agents