[Application of RIFLE criteria for acute renal failure in patients treated with continuous renal replacement therapy].
OBJECTIVE
To determine the optimal timing of treating acute renal failure (ARF) patients in intensive care unit (ICU) with RIFLE (risk of renal failure, injury to the kidney, failure of kidney function, loss of kidney function and end-stage renal failure) classification using continuous renal replacement therapy (CRRT). And to evaluate the association between mortality and RIFLE classification in the same patients.


METHODS
Clinical data were collected from 103 ARF patients in ICU from 2000 to 2007.


RESULTS
The 30-days hospital mortality rate was 45.6%. The 30 days' hospital mortality rates of RIFLE-R, RIFLE-I and RIFLE-F were 25.0%, 20.0% and 57.3% respectively.


CONCLUSIONS
Survival rate of ARF patients can be manifestly elevated if CRRT is performed before RIFLE-F. The patients in RIFLE-F category have a significantly higher mortality than RIFLE-R and -I patients. The RIFLE criteria is fit for ARF classification system.
Pan
Jing-Ye
JY
Intensive Care Unit, First Affiliated Hospital, Wenzhou Medical College, Wenzhou 325000, China. panjingye@hospl.ac.cn
Tao
Fu-Zheng
FZ
Zhang
Jin-Bo
JB
Chen
Jie
J
Huang
Yue-Yue
YY
Ma
Ji-Hong
JH
Wang
Xiao-Rong
XR
Wang
Dan
D
D058186:Acute Kidney Injury / Q000628:therapy*; D006801:Humans; D012015:Reference Standards; D017582:Renal Replacement Therapy / Q000592:standards* / Q000706:statistics & numerical data; D015996:Survival Rate; D016896:Treatment Outcome