NO Signals from the Cancer Stem Cell Niche.
Characterization of signaling pathways that control cancer stem cells may lead to more effective treatments against cancer. In this issue of Cell Stem Cell, a study by Charles et al. (2010) identifies the NO and Notch pathways as important regulators of the perivascular niche of cancer stem cells in glioma.
Seoane
Joan
J
Institució Catalana de Recerca i Estudis Avançats,Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Autonomous University of Barcelona, Psg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. jseoane@vhio.net