Familial isolated primary hyperparathyroidism with double adenoma.
Familial hyperparathyroidism includes the diagnoses of multiple endocrine neoplasia type 1, type 2A, and familial isolated primary hyperparathyroidism. Familial isolated primary hyperparathyroidism is a rare, distinct form of familial primary hyperparathyroidism, mainly due to four-gland hyperplasia or single-gland adenoma. We describe our success in treating a 24-year-old woman with familial isolated primary hyperparathyroidism with resection of double adenoma, using the guide of intraoperative parathyroid hormone (PTH) monitoring. Familial isolated primary hyperparathyroidism usually presents with four-gland hyperplasia or single-gland adenoma. However, double adenoma should be considered in the differential diagnosis. Using intraoperative parathyroid hormone levels and minimal-access surgery in familial isolated primary hyperparathyroidism may be promising.
Division of Endocrine and Oncological Surgery, Department of Surgery, Tulane University School of Medicine, and Tulane University Hospital, New Orleans, LA, USA. ekandil@tulane.edu
Emad
E
Kandil
Haytham H
HH
Alabbas
Ying W
YW
Lum
Anthony P
AP
Tufaro
D000236:Adenoma / Q000150:complications / Q000235:genetics* / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000235:genetics*; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D010282:Parathyroid Neoplasms / Q000150:complications / Q000235:genetics* / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods; D010375:Pedigree; D055815:Young Adult