A novel technique for ultra-low contrast administration during angiography or intervention.
Contrast-induced nephropathy (CIN) after coronary angiography or intervention is associated with substantial morbidity. The data supporting various prophylactic measures and adjunctive therapies to prevent this complication are conflicting. However, contrast volume is clearly related to CIN after percutaneous coronary intervention (PCI), and the risk of CIN has been shown to be directly related to contrast dose. Therefore, minimizing contrast exposure is a primary method to reduce the risk of CIN, especially in at-risk patients. We report a novel technique designed to deliver ultra-low (<15 cm(3)) volume contrast to patients with chronic kidney disease undergoing coronary angiography and PCI.
Scripps Clinic, La Jolla, CA, USA.
Keshav R
KR
Nayak
Hirsch S
HS
Mehta
Matthew J
MJ
Price
Robert J
RJ
Russo
Curtiss T
CT
Stinis
Jeffrey W
JW
Moses
Roxana
R
Mehran
Martin B
MB
Leon
David E
DE
Kandzari
Paul S
PS
Teirstein
D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D002932:Cineangiography; D003287:Contrast Media / Q000008:administration & dosage* / Q000009:adverse effects; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D015607:Stents; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
D015415:Biomarkers; D003287:Contrast Media; D003404:Creatinine