On-bead library screening made easier.
In this issue of Chemistry & Biology, Astle et al. report the rapid identification of the most active hits from a large one-bead-one-compound peptoid library by magnetic sorting and without the need for labor-intensive resynthesis of the hits.
Pei
Dehua
D
Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA.