The metabolic syndrome in cancer survivors.
The metabolic syndrome, as a cluster of cardiovascular risk factors, may represent an important connection between cancer treatment and its common late effect of cardiovascular disease. Insight into the aetiology of the metabolic syndrome after cancer treatment might help to identify and treat cancer survivors with increased cardiovascular risk. In this review, we summarise current knowledge on the prevalence and pathophysiology of the metabolic syndrome in cancer survivors, and discuss current intervention strategies with an emphasis on new developments.
de Haas
Esther C
EC
Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.
Oosting
Sjoukje F
SF
Lefrandt
Joop D
JD
Wolffenbuttel
Bruce Hr
BH
Sleijfer
Dirk Th
DT
Gietema
Jourik A
JA
D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D015995:Prevalence; D017741:Survivors