Episodic memory and organizational strategy in free recall in unipolar depression: the role of cognitive support and executive functions.
Executive functioning and memory impairment have been demonstrated in adults with depression. Executive functions and memory are related, mainly when the memory tasks require controlled processes (attentional resource demanding processes)--that is, when a low cognitive support (external aid) is provided. A cross-sectional study was carried out on 45 participants: 21 with depression, and 24 healthy controls matched for age, verbal ability, education level, and anxiety score. Cognitive support was manipulated by providing a categorized word list at encoding, presented either clustered (high cognitive support) or randomized (low cognitive support) to both depressed and healthy adults. The number of words recalled was calculated, and an index of clustering was computed to assess organizational strategies. Participants were also administered cognitive tests (executive functions, cognitive speed, and categorical fluency) to explore the mediators of organizational strategies. Depressed participants had greater difficulty recalling and organizing the words, but the differences between the two groups were reduced for both measures when high cognitive support was provided at encoding. Healthy adults performed better on all cognitive tests. Statistical analyses revealed that in the depressed group, executive functions were the only variable associated with clustering and only when low cognitive support was provided. These findings support the view that the decrement in executive function due to depression may lead to impairment in organization when this mnemonic strategy has to be self-initiated.
UMR-CNRS 6234: Centre de Recherches sur la Cognition et l'Apprentissage, Universite de Tours, Tours, France. taconnat@univ-tours.fr
Laurence
L
Taconnat
Alexia
A
Baudouin
Severine
S
Fay
Naftali
N
Raz
Badiaa
B
Bouazzaoui
Wissam
W
El-Hage
Michel
M
Isingrini
Anne-Marie
AM
Ergis
D000328:Adult; D003071:Cognition / Q000502:physiology*; D003463:Cues; D003865:Major Depressive Disorder / Q000523:psychology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders; D011939:Mental Recall / Q000502:physiology*; D009483:Neuropsychological Tests; D011932:Reading; D014936:Word Association Tests; D055815:Young Adult