Ocular blood-flow hemodynamics before and after application of a laser in situ keratomileusis ring.
OBJECTIVE
To evaluate blood-flow responses before and after microkeratome application.


METHODS
School of Life and Health Sciences, Aston University, Birmingham, United Kingdom.


METHODS
Hemodynamic responses were measured in eyes of healthy volunteers before and after transient elevation in intraocular pressure (IOP) resulting from microkeratome application. The IOP was elevated above 85 mm Hg for 90 seconds. Blood-flow responses were measured using color Doppler imaging, Heidelberg retinal flowmetry, and an ocular blood-flow analyzer.


RESULTS
The study included 10 eyes. There was no difference in ocular-perfusion measurements before or after IOP elevation using any measurement system.


CONCLUSIONS
In normal healthy eyes, once suction was released, blood-flow responses returned immediately to normal levels.
Conway
Miriam L
ML
Department of Optometry and Visual Science, City University, Northampton Square, London EC1V OHB, United Kingdom. miriam.conway.1@city.ac.uk
Wevill
Mark
M
Benavente-Perez
Alexandra
A
Hosking
Sarah L
SL
D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D020731:Keratomileusis, Laser In Situ / Q000295:instrumentation*; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology*; D009898:Optic Disk / Q000098:blood supply; D011430:Propoxycaine / Q000008:administration & dosage; D012039:Regional Blood Flow / Q000502:physiology; D012161:Retinal Artery / Q000502:physiology*; D013396:Suction / Q000295:instrumentation; D014065:Tonometry, Ocular; D018615:Ultrasonography, Doppler, Color; D014792:Visual Acuity / Q000502:physiology
C005717:proxymetacaine; D011430:Propoxycaine