Correlation between pre-operative brain magnetic resonance angiography findings and intra-operative cerebral oxygen saturation during coronary artery bypass graft surgery.
Coronary artery bypass graft (CABG) patients often have cerebrovascular disease and pre-operative brain magnetic resonance angiography (MRA) frequently reveals cerebral vasculature stenosis. This study was designed to investigate whether pre-operative MRA findings correlated with regional cerebral oxygen saturation (ScO(2)) in 120 patients undergoing on-pump or off-pump CABG. Following MRA examination, patients were divided into six groups of 20 patients each based on MRA findings (no stenosis, mild stenosis or severe stenosis) and procedure (on-pump or off-pump CABG). Mean ScO(2) values over 3 min were determined at seven periods during surgery. Patients with severe cerebrovascular stenosis showed significantly lower ScO(2) than other groups during off-pump CABG. During on-pump CABG, ScO(2) decreased significantly during cardiopulmonary bypass in all groups and was significantly lower in the severe stenosis group. Pre-operative MRA and intra-operative ScO(2) monitoring may help to identify patients at increased risk of brain damage during or following CABG.
Roh
Y-J
YJ
Department of Anaesthesiology, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Choi
J-W
JW
Suh
J-H
JH
Shim
J-Y
JY
Choi
I-C
IC
D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D001026:Coronary Artery Bypass; D003710:Demography; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D057234:Preoperative Period; D011859:Radiography
D010100:Oxygen