Aqueous iodine(III)-mediated stereoselective oxidative cyclization for the synthesis of functionalized fused dihydrofuran derivatives.
An efficient aqueous oxidative cyclization mediated by the combination of iodosobenzene with tetra-(n-butyl)ammonium iodide provides a new convenient and useful route to functionalized fused dihydrofuran derivatives in moderate to excellent yields with high diastereoselectivities.
Ye
Yang
Y
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Wang
Linfei
L
Fan
Renhua
R
D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014867:Water / Q000737:chemistry
D005663:Furans; D014867:Water; D007455:Iodine