Rare coexistence of gouty and septic arthritis: a report of 14 cases.
OBJECTIVE
To analyse the characteristic features of patients with coexistence of gouty arthritis and pyarthrosis at our university hospital in southern Taiwan, an area with high prevalence of hyperuricemia and gout.


METHODS
A retrospective chart review was performed for patients who had concomitant gouty and septic arthritis from July 1998 to June 2008. Clinical and laboratory data of these patients were analysed. Furthermore, a comparison was made with published cases in English literature.


RESULTS
Fourteen cases with coexistence of gouty arthritis and pyarthrosis have been identified during the past 10 years. There were 13 male and 1 female, all of Han Chinese in ethnicity, with ages ranging from 45 to 85 and an average of 63.7 years. At disease presentation, there were 11 oligoarticular cases (78.6%), 2 monoarticular cases (14.3%) and 1 polyarticular case (7.1%). Ankle and knee joints were most commonly involved. Bacteriological analyses demonstrated gram-positive cocci in 12 cases, of these 10 were oxacillin-sensitive Staphylococcus aureus (71.4%). Multiple tophi deposition was noted in 13 patients (92.9%) and among them 11 patients (84.6%) had associated chronic kidney disease.


CONCLUSIONS
Different clinical presentations and bacteriological characteristics have been identified in the present series. While the mechanisms responsible for such a coexistence remain to be elucidated, these cases underline the importance of thorough evaluation of the aspirated synovial fluid. Our report adds a novel insight into the understanding of the clinical and microbiological manifestations of such a rare concurrence of gouty and septic arthritis.
Section of Rheumatology and Immunology, Department of Internal Medicine, National Cheng Kung University Hospital and Dou-Liou Branch.
C-T
CT
Weng
M-F
MF
Liu
L-H
LH
Lin
M-Y
MY
Weng
N-Y
NY
Lee
A-B
AB
Wu
K-Y
KY
Huang
J-W
JW
Lee
C-R
CR
Wang
D000368:Aged; D000369:Aged, 80 and over; D015210:Arthritis, Gouty / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D001170:Arthritis, Infectious / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D003646:Debridement; D005260:Female; D006801:Humans; D007596:Joints / Q000382:microbiology; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000150:complications; D013211:Staphylococcus aureus