Miniaturized planar chromatography using office peripherals.
High-performance thin-layer chromatography is a separation technique commonly used to identify and quantify components in chemical mixtures. Sophisticated analytical tools are required to extract the full analytical power from this technique and especially for miniaturized planar chromatography its utility has not been harnessed. A new approach uses an elegant, simplified system assembled from ordinary consumer printers and scanners to perform separations on monolithic and nanostructured ultrathin-layer phases. This system is shown to outperform existing planar chromatographic tools for analysis on miniaturized plates. Analysis can be completed in a manner of minutes, running numerous samples in parallel at a reduced cost, with very low sample and reagent volumes, all using a familiar computer interface with common office peripherals.
Morlock
Gertrud E
GE
Institute of Food Chemistry, University of Hohenheim, Garbenstrasse 28, 70599 Stuttgart, Germany. gmorlock@uni-hohenheim.de
Oellig
Claudia
C
Bezuidenhout
Louis W
LW
Brett
Michael J
MJ
Schwack
Wolfgang
W