Retinal complications of juvenile idiopathic arthritis-related uveitis: a microperimetry and optical coherence tomography study.
OBJECTIVE
To evaluate ocular complications of juvenile idiopathic arthritis (JIA)-related uveitis; to study macular morphology and sensitivity.


METHODS
Retrospective chart review of 67 patients. Fourteen consecutive patients (24 eyes) observed from January to December 2008 were submitted to optical coherence tomography study (OCT) and microperimetry MP-1 examination.


RESULTS
Most frequent complications were posterior synechiae (63.0%), band keratopathy (53.9%), and cataract (31.8%). Posterior complications were documented in 37.0% of eyes: 13.8% macular edema, 12.0% papillitis, 6.8% epiretinal membranes, 2.5% retinal vasculitis, 1.7% retinal detachment. At OCT examination 25.0% of eyes presented macular edema; macular sensitivity by MP-1 was < or = 16.5 dB in 25.0% of eyes.


CONCLUSIONS
Visual prognosis is good despite ocular complications. Incidence of macular edema seems to be higher when using OCT. Microperimetry may represent a useful tool in detecting alteration in retinal sensitivity that may supplement visual acuity in the follow-up of macular edema.
Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Rome, Italy. mpparoli@jumpy.it
Maria Pia
MP
Paroli
Giovanni
G
Spinucci
Claudia
C
Fabiani
Paola
P
Pivetti-Pezzi
D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications* / Q000473:pathology; D002648:Child; D005128:Eye Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D008269:Macular Edema / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D012163:Retinal Detachment / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014605:Uveitis / Q000150:complications* / Q000473:pathology; D058609:Visual Field Tests / Q000379:methods*