Surgery-related death, complicated wounds, and anastomosis healing in HIV-positive patients with considerable immune deficit: assumption and reality.
This is to appreciate of truthness of predicate, that HIV-positive patients have, in most cases, the chance to develop postoperative complications and unsuccessful results. In the study, we assessed the experience of the first author in 3 years of expert work in Botswana, Southern Africa, and used nonparametric tests for statistical assessment of the results in those patients. In addition to clinical follow-up are patients assessed through study of CD4+ T lymphocytes and CD8+ T lymphocytes levels. Only in the most serious immunodeficiency group (Group C) were statistically important deviations in deaths and complications of wounds and anastomoses healing. For example, comparing HIV-positive patients and the HIV-negative population using a CD4+ T-lymphocyte level < 200 mm3, we can see the differences in the mortality rate: HIV-positive patients, 23.96%; HIV negative population 8.11%. The complication rate in HIV-positive patients with a CD4 level < 200 mm3 was 38.54% and in the HIV-negative population was 9.46%. The study disputes the myth that, in the majority of HIV-positive patients, we can expect limited surgical results and a larger rate of deaths and complications in wounds and anastomoses healing.
Hájek
Marcel
M
Department of Surgery, University Hospital, Pilsen, Czech Republic.
Novák
Karel
K
Zikmundová
Kvetoslava
K
D000328:Adult; D000714:Anastomosis, Surgical; D015496:CD4-Positive T-Lymphocytes; D018414:CD8-Positive T-Lymphocytes; D016009:Chi-Square Distribution; D005260:Female; D006679:HIV Seropositivity / Q000276:immunology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000276:immunology* / Q000401:mortality*; D011446:Prospective Studies; D013019:South Africa / Q000453:epidemiology; D018709:Statistics, Nonparametric; D014945:Wound Healing / Q000276:immunology*