title: Case series of resection of pelvic leiomyoma extending into the right heart: surgical safeguards and clinical follow-up.
abstract: OBJECTIVE
  To analyze the clinical features, surgical management and oncologic results of a series of six patients undergoing seven operations for resection of uterine leiomyoma extending into the right cardiac chambers.
  
  
  METHODS
  A retrospective review of patients operated on for surgical resection of a pelvic leiomyomatous mass originating from the uterus and extending into the right cardiac chambers was performed. The most common symptoms at presentation were syncope and dyspnea; two patients were asymptomatic. Four patients had been misdiagnosed as having intracardiac thrombus or primary cardiac tumor. The intracardiac and upper intracaval portion was removed under circulatory arrest in moderate hypothermia; the remaining portion was removed by caval incision. In one patient with cardiogenic shock, the sole intracardiac portion of the mass was removed at primary surgery. A mean of 2.8 +/- 1.5 years of follow-up was available, consisting of clinical and radiological tests (computed tomography scan, echocardiography).
  
  
  RESULTS
  There were no cases of operative mortality in the present series. No recurrence was observed at the end of the follow-up in all cases of complete resection of the mass from its intracardiac to its pelvic end. Conversely, in the only case in which partial resection was performed due to the patient's clinical condition, recurrence of the intracardiac involvement was observed 6 months after primary surgery.
  
  
  CONCLUSIONS
  Radical resection is curative for uterine leiomyomatosis extending into the right cardiac chambers. Surgery can be afforded with acceptable risks. A high level of suspicion for intracardiac extension of pelvic leiomyomatosis should be retained in the presence of a floating mass within the right cardiac chambers. Such a finding should prompt radiographic evaluation of the abdomen and the pelvis.
authors.affiliation: Division of Cardiac Surgery, Catholic University, Rome, Italy. amedeo.anselmi@alice.it
authors.forename: Amedeo
authors.initials: A
authors.lastname: Anselmi
authors.forename: Vasileios
authors.initials: V
authors.lastname: Tsiopoulos
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Perri
authors.forename: Michele
authors.initials: M
authors.lastname: Palladino
authors.forename: Angela
authors.initials: A
authors.lastname: Ferrante
authors.forename: Franco
authors.initials: F
authors.lastname: Glieca
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures; D005260:Female; D006325:Heart Atria / Q000473:pathology / Q000601:surgery; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*; D014656:Vascular Surgical Procedures; D014682:Vena Cava, Inferior / Q000473:pathology / Q000601:surgery