Piptaderol from Piptadenia africana.
A new glyceryl derivative (Glyceryl-1-hexacosanoate) and a flavone derivative (methyletherapigenin) were isolated from the stem bark extract of Piptadenia africana, a western Cameroonian plant species. Common terpenes like sitosterol, beta-amyrin and eicosane were also isolated. These compounds were identified using physical and spectroscopic methods including mp, IR, (1)H and (13)C-NMR, DEPT, COSY, HMQC, HMBC, EI MS, HREI MS as well as some chemical transformations. The antibacterial activity of the extract, the fractions and the pure compounds is also discussed.
Mbouangouere
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Department of Chemistry, Faculty of Science, University of Dschang, Box 67 Dschang, Cameroon. tirouka@yahoo.fr
Tane
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Ngamga
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Djemgou
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Choudhary
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Ngadjui
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