title: Descriptive study of enzootic nasal adenocarcinoma in goats in southwestern China.
abstract: This is the first report on enzootic nasal adenocarcinoma (ENA) in goats (Nanjiang Yellow goats and Jianyang Big-ear Black goats) in southwestern China. The clinical, histological and ultrastructural features of ENA in goats were described. From July 2007 to May 2009, 21 cases of ENA in goats, from 6 months to 8 years old, were diagnosed solely in one big herd. Clinically, the affected goats showed nasal discharge, facial swelling, sneezing, stertorous breathing and weight loss. Tumours that originated from the ethmoid area of the nasal cavity were unilateral (18/21) or bilateral (3/21). All tumours were classified as low grade adenocarcinomas by histopathological examination and were displayed a combination of tubular and papillary growth. No metastases were detected in regional lymph nodes, brain or other organs. Ultrastructurally, virus-like particles with an average diameter between 80 and 110 nm were observed in 5/7 examined tumours.
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an, Sichuan, China.
authors.forename: G
authors.initials: G
authors.lastname: Yi
authors.forename: W
authors.initials: W
authors.lastname: Kaiyu
authors.forename: Y
authors.initials: Y
authors.lastname: Qigui
authors.forename: Y
authors.initials: Y
authors.lastname: Zhongqiong
authors.forename: Y
authors.initials: Y
authors.lastname: Yingdong
authors.forename: C
authors.initials: C
authors.lastname: Defang
authors.forename: H
authors.initials: H
authors.lastname: Jinlu
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary* / Q000821:virology; D000818:Animals; D002455:Cell Division; D002681:China; D015511:Goat Diseases / Q000473:pathology* / Q000821:virology; D006041:Goats; D009669:Nose Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary* / Q000821:virology; D014780:Viruses / Q000302:isolation & purification / Q000648:ultrastructure; D015431:Weight Loss