Emerging applications of nanomedicine for the diagnosis and treatment of cardiovascular diseases.
Nanomedicine is an emerging field that utilizes nanotechnology concepts for advanced therapy and diagnostics. This convergent discipline merges research areas such as chemistry, biology, physics, mathematics and engineering. It therefore bridges the gap between molecular and cellular interactions, and has the potential to revolutionize medicine. This review presents recent developments in nanomedicine research poised to have an important impact on the treatment of cardiovascular disease. This will occur through improvement of the diagnosis and therapy of cardiovascular disorders as atherosclerosis, restenosis and myocardial infarction. Specifically, we discuss the use of nanoparticles for molecular imaging and advanced therapeutics, specially designed drug eluting stents and in vivo/ex vivo early detection techniques.
Godin
Biana
B
Department of NanoMedicine and Biomedical Engineering, The University of Texas Health Science Center at Houston,1825 Pressler, Suite 537, Houston, TX 77030, USA.
Sakamoto
Jason H
JH
Serda
Rita E
RE
Grattoni
Alessandro
A
Bouamrani
Ali
A
Ferrari
Mauro
M
D000818:Animals; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000188:drug therapy*; D003952:Diagnostic Imaging / Q000379:methods; D054855:Drug-Eluting Stents; D042241:Early Diagnosis; D006801:Humans; D050997:Nanomedicine / Q000379:methods*; D053758:Nanoparticles / Q000627:therapeutic use