title: Angular dose dependence of Matrixx TM and its calibration.
abstract: One of the applications of MatriXX (IBA Dosimetry) is experimental verification of dose for IMRT, VMAT, and tomotherapy. For cumulative plan verification, dose is delivered for all the treatment gantry angles to a stationary detector. Experimental calibration of MatriXX detector recommended by the manufacturer involves only AP calibration fields and does not address angular dependency of MatriXX. Angular dependency may introduce dose bias in cumulative plan verification if not corrected. For this reason, we characterized angular dependency of MatriXX and developed a method for its calibration. We found relatively large discrepancies in responses to posterior vs. anterior fields for four MatriXX (Evolution series) detectors (up to 11%), and relatively large variability of responses as a function of gantry angle in the gantry angle ranges of 91 degrees-110 degrees and 269 degrees-260 degrees. With our calibration method, the bias due to angular dependency is effectively removed in experimental verification of IMRT and VMAT plans.
authors.affiliation: Division of Medical Physics and Biophysics, Department of Radiation Oncology, Dana-Farber Cancer Institute/ Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. lwolfsberger@lroc.harvard.edu
authors.forename: Luciant D
authors.initials: LD
authors.lastname: Wolfsberger
authors.forename: Matthew
authors.initials: M
authors.lastname: Wagar
authors.forename: Paige
authors.initials: P
authors.lastname: Nitsch
authors.forename: Mandar S
authors.initials: MS
authors.lastname: Bhagwat
authors.forename: Piotr
authors.initials: P
authors.lastname: Zygmanski
mesh_terms: D001822:Body Burden; D002138:Calibration; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D011786:Quality Control; D011874:Radiometry; D011879:Radiotherapy Dosage; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation / Q000379:methods / Q000592:standards