title: Human immunodeficiency virus (HIV) in older people.
abstract: The number of older people living with human immunodeficiency virus (HIV) in the UK is rising. Older people are at risk of acquiring HIV infection for a multitude of reasons. This, combined with effective HIV treatment which has significantly prolonged life expectancy, means that health care professionals working in the UK can expect to see increasing numbers of older people with HIV infection. In this review article, we summarise the epidemiology of HIV amongst older people, including data from our local cohort in the city of Sheffield, UK. We discuss specific and practical issues in older patients including why older people are at risk, how to make a diagnosis and the importance of doing so early, guidelines for HIV testing and an update on anti-retroviral therapy including drug interactions and side effects.
authors.affiliation: Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Herries Road, Sheffield, UK. gary.pratt@live.co.uk
authors.forename: Gary
authors.initials: G
authors.lastname: Pratt
authors.forename: Kate
authors.initials: K
authors.lastname: Gascoyne
authors.forename: Katherine
authors.initials: K
authors.lastname: Cunningham
authors.forename: Anne
authors.initials: A
authors.lastname: Tunbridge
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000453:epidemiology; D000367:Age Factors; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology* / Q000503:physiopathology; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011379:Prognosis; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology