title: Ten-year experience of 44 patients with moyamoya disease from a single institution.
abstract: We analyzed the records of 44 patients with moyamoya disease evaluated and treated at our Institute from 1998 until 2007. Out of 44 patients, 18 (41%) were in the paediatric age group and 26 (59%) were adults. Presentation was ischemic in 14 (32%) and hemorrhagic in 30 patients (68%). Revascularization was performed in 11 patients (five patients with ischemic presentation and six with hemorrhagic presentation): nine patients underwent indirect revascularization procedures only and two patients underwent indirect revascularization procedures and a combined superficial temporal artery-middle cerebral artery bypass. Thirty-six patients (81.8%) were available for follow-up. Out of 11 patients who underwent revascularization procedures, none had further hemorrhagic or ischemic episodes. Out of the 19 conservatively managed patients who were followed-up, seven (36.8%) developed new episodes of ischemia (n=2) or hemorrhage (n=5). In-hospital mortality was 6.8% (three patients), all of whom were in the hemorrhagic presentation group.
authors.affiliation: Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India.
authors.forename: Anil Kumar
authors.initials: AK
authors.lastname: Garg
authors.forename: Ashish
authors.initials: A
authors.lastname: Suri
authors.forename: Bhawani Shankar
authors.initials: BS
authors.lastname: Sharma
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000098:blood supply / Q000601:surgery; D002545:Brain Ischemia / Q000209:etiology / Q000601:surgery; D002548:Cerebral Revascularization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology / Q000601:surgery; D020300:Intracranial Hemorrhages / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009072:Moyamoya Disease / Q000150:complications / Q000473:pathology / Q000601:surgery*; D055815:Young Adult