title: Vitamin D, the immune system and asthma.
abstract: The effects of vitamin D on bone metabolism and calcium homeostasis have long been recognized. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role in both the innate and cell-mediated immune systems. Vitamin D deficiency has been found to be associated with several immune-mediated diseases, susceptibility to infection and cancer. Recently, there has been increasing interest in the possible link between vitamin D and asthma. Further elucidation of the role of vitamin D in lung development and immune system function may hold profound implications for the prevention and treatment of asthma.
authors.affiliation: Channing Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA Tel.: +1 617 525 0874 nlange@partners.org.
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Lange
authors.forename: Augusto
authors.initials: A
authors.lastname: Litonjua
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Hawrylowicz
authors.forename: Scott
authors.initials: S
authors.lastname: Weiss