title: Synthesis and redox-enzyme modulation by amino-1,4-dihydro-benzo[d][1,2]dithiine derivatives.
abstract: A convenient method to prepare a series of benzodithiine derivatives was developed, via the synthesis of cyclic disulfide building blocks containing an amino-group linker. Some of the novel cyclic disulfide compounds are shown to modulate the activity of the redox-enzyme glutathione reductase.
authors.affiliation: School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan, PR00936, Puerto Rico.
authors.forename: Sandraliz
authors.initials: S
authors.lastname: Espinosa
authors.forename: Melissa
authors.initials: M
authors.lastname: Solivan
authors.forename: Cornelis P
authors.initials: CP
authors.lastname: Vlaar