Simultaneous determination of seven neonicotinoid pesticide residues in food by ultraperformance liquid chromatography tandem mass spectrometry.
The present study developed an improved analytical method for simultaneous quantification of seven neonicotinoids in food by ultraperformance liquid chromatography combined with electrospray ionization triple quadrupole tandem mass spectrometry (UPLC-MS/MS) under the multiple reaction monitoring (MRM) mode. The optimization of extraction, cleanup, UPLC separation and MS/MS parameters of analytes were especially focused on. The low limits of quantification (LOQs) of neonicotinoids ranged from 0.1 to 6 microg kg(-1). Meanwhile, reasonable recoveries (65-120%) of seven neonicotinoids for food including apple, cabbage, potato, rice, tea, milk, chicken, pork and egg were demonstrated in different spiked levels within their respective linear range (0.025-150 microg kg(-1)). The developed analytical method would be appropriate for the routine, high throughput, high sensitivity quantification of seven neonicotinoids using simple sample pretreatment.
Liu
Shaoying
S
Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, P. R. China.
Zheng
Zuntao
Z
Wei
Fanglin
F
Ren
Yiping
Y
Gui
Wenjun
W
Wu
Huiming
H
Zhu
Guonian
G
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005504:Food Analysis; D057230:Limit of Detection; D008460:Meat / Q000032:analysis; D010573:Pesticide Residues / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014675:Vegetables / Q000737:chemistry
D010573:Pesticide Residues