title: Tandem palladium-catalyzed addition/cyclocarbonylation: an efficient synthesis of 2-heteroquinazolin-4(3H)-ones.
abstract: A highly practical and efficient method for the synthesis of 2-heteroquinazolin-4(3H)-ones has been developed by a palladium-catalyzed tandem reaction. Under mild reaction conditions (80 degrees C, 100 psi), a wide variety of 2-heteroquinazolin-4(3H)-ones were obtained in good to excellent yields.
authors.affiliation: Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
authors.forename: Fanlong
authors.initials: F
authors.lastname: Zeng
authors.forename: Howard
authors.initials: H
authors.lastname: Alper
mesh_terms: D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D052999:Quinazolinones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D052999:Quinazolinones; D010165:Palladium