Ionic liquid mediated synthesis of 5-halouracil nucleosides: key precursors for potential antiviral drugs.
Synthesis of antiviral 5-halouracil nucleosides, also used as key precursors for the synthesis of other potential antiviral drugs, has been demonstrated using ionic liquids as convenient and efficient reaction medium.
Kumar
Vineet
V
Laboratory of Synthetic Chemistry, SAIC-Frederick, NCI-Frederick, Frederick, Maryland 21702, USA.
Malhotra
Sanjay V
SV
D000107:Acetylation; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry; D055808:Drug Discovery; D054879:Halogenation; D052578:Ionic Liquids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014529:Uridine / Q000737:chemistry*
D000998:Antiviral Agents; D052578:Ionic Liquids; D014529:Uridine