Long-term outcome, including pregnancy rate, recurrence rate and ovarian reserve, after laparoscopic laser ablation surgery in infertile women with endometrioma.
OBJECTIVE
To retrospectively assess the long-term outcome, including pregnancy rate, recurrence rate and ovarian reserve, after laser ablation surgery in infertile women with endometrioma.


METHODS
From March 1997 to June 2007, 45 subfertile women underwent ablation surgery with a potassium-titanyl-phosphate laser for ovarian endometrioma. These patients were reviewed retrospectively.


RESULTS
Of the 45 women, 22 became pregnant spontaneously. Among the 23 women who did not become pregnant after more than 6 months postoperatively, 16 elected to undergo in vitro fertilization (IVF), 12 of them became pregnant. The remaining 11 women did not become pregnant. Eleven women had recurrence detected by ultrasound. The mean number of oocytes retrieved per cycle during IVF was 7.3 +/- 3.6 and 4.6 +/- 2.7 from the ovary treated by ablation surgery and the contralateral ovary, respectively.


CONCLUSIONS
The overall long-term pregnancy rate (combining spontaneous pregnancy and IVF) after laparoscopic ablation surgery for endometrioma was 75.6%. Surgery did not have any adverse effect on the ovarian reserve during subsequent IVF.
Shimizu
Yoshihiko
Y
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Shiga, Japan. oshimi@belle.shiga-med.ac.jp
Takashima
Akiko
A
Takahashi
Kentaro
K
Kita
Nobuyuki
N
Fujiwara
Mutsuko
M
Murakami
Takashi
T
D004715:Endometriosis / Q000517:prevention & control / Q000601:surgery*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications*; D010535:Laparoscopy / Q000009:adverse effects*; D053685:Laser Therapy / Q000009:adverse effects*; D009364:Neoplasm Recurrence, Local; D009865:Oocytes; D011247:Pregnancy; D018873:Pregnancy Rate; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D014591:Uterine Diseases / Q000517:prevention & control / Q000601:surgery*