title: Pregnane glycoside from Hemidesmus indicus as a potential anti-oxidant and anti-dyslipidemic agent.
abstract: A new pregnane glycoside hindicusine (1) was isolated from the CHCl(3)-EtOH (3 : 2) extract of Hemidesmus indicus, whose structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (5) were evaluated for their anti-oxidant and anti-dyslipidemic activities.
authors.affiliation: Department of Chemistry, University of Lucknow, Lucknow, India. alkaarunsethi@rediffmail.com
authors.forename: Arun
authors.initials: A
authors.lastname: Sethi
authors.forename: Akriti
authors.initials: A
authors.lastname: Bhatia
authors.forename: Sanjay
authors.initials: S
authors.lastname: Srivastava
authors.forename: Geetika
authors.initials: G
authors.lastname: Bhatia
authors.forename: M M
authors.initials: MM
authors.lastname: Khan
authors.forename: A K
authors.initials: AK
authors.lastname: Khanna
authors.forename: J K
authors.initials: JK
authors.lastname: Saxena
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D031102:Hemidesmus / Q000737:chemistry*; D006949:Hyperlipidemias / Q000139:chemically induced / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000737:chemistry* / Q000627:therapeutic use*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011092:Polyethylene Glycols / Q000633:toxicity; D011278:Pregnanes / Q000737:chemistry*; D051381:Rats
chemical_list: D000975:Antioxidants; D006027:Glycosides; D000960:Hypolipidemic Agents; D011278:Pregnanes; D011092:Polyethylene Glycols; C016811:tyloxapol