[Traditional Chinese medicine Drynaria fortunei J. Smith naringin promotes proliferation and differentiation of human periodontal ligament cells].
To investigate the effects of Drynaria fortunei J. Smith naringin (DFSN) on proliferation and differentiation of human periodontal ligament cells (hPDLC).



Cultured human periodontal ligament cells were treated with DFSN at different concentrations. Cell proliferation was determined by MTT method; cell differentiation was evaluated through the examination of alkaline phosphate (ALP) activities.



DFSN in a concentration ranged from 0.01 mu mol/L to 10 mu mol/L showed a promoting effect on proliferation of hPDLC (P< 0.05), and it also promoted ALP activities of hPDLC (P<0.05).



Drynaria fortunei J. Smith naringin can promotes the proliferation and differentiation of human periodontal ligament cells.
Hu
Qi-yong
QY
Department of Stomatology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Chen
Li-li
LL
Wang
Ren-fei
RF
D002454:Cell Differentiation / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology; D044950:Flavanones / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D010006:Osteoblasts / Q000166:cytology*; D010513:Periodontal Ligament / Q000166:cytology*; D029621:Polypodiaceae / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D044950:Flavanones; C005274:naringin