Constituents from the seeds of Brucea javanica with inhibitory activity of Tobacco mosaic virus.
Three new constituents were obtained along with 10 known compounds from the seeds of Brucea javanica. The structures of these compounds were determined based on spectral and chemical evidence. These new compounds included a monoterpenoid glycoside and two sesquiterpenes. Bioactivity screening of these constituents showed that compounds 1, 3, 8, 9, and 13 with obvious activities in inhibiting multiplication of the Tobacco mosaic virus.
Chen
Qi-Jian
QJ
Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
Ouyang
Ming-An
MA
Tan
Qing-Wei
QW
Zhang
Zheng-Kun
ZK
Wu
Zu-Jian
ZJ
Lin
Qi-Ying
QY
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032269:Brucea / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014027:Tobacco Mosaic Virus / Q000187:drug effects*
D000972:Antineoplastic Agents, Phytogenic; D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D005697:Galactosides; D012717:Sesquiterpenes; D013729:Terpenes; C547892:brucojavan 1; C547893:brucojavan 2