title: Management of aromatase inhibitor-induced arthralgia.
abstract: Aromatase inhibitors (AIs) are commonly used as adjuvant treatment in postmenopausal women with hormone receptor-positive early breast cancer. With both steroidal and nonsteroidal AIs, AI-induced arthralgia is frequently observed. The mechanism of AI-induced arthralgia remains unknown, and the data available from clinical trails using AIs are limited. We review the pertinent information from a clinical perspective, including an algorithm to treat AI-induced arthralgia.
authors.affiliation: jawaid.younus@lhsc.on.ca
authors.forename: J
authors.initials: J
authors.lastname: Younus
authors.forename: L
authors.initials: L
authors.lastname: Kligman