Magnetic resonance angiography findings in patients with ischemic stroke from North India.
BACKGROUND
We sought to evaluate the magnetic resonance (MR) angiography (MRA) findings in patients with ischemic stroke (IS) from North India and correlate the changes with various conventional and nonconventional risk factors.


METHODS
The study took place at a tertiary care teaching hospital. The patients with IS were clinically evaluated including body mass index, dietary habits, and family history of stroke. MR imaging, MRA, and testing for blood sugar, lipid profile, B12, folic acid, and homocysteine were carried out. The MRA abnormalities were considered significant if stenosis was 50% or greater and these were categorized into extracranial (EC), intracranial (IC), or combined lesions. The location of infarct on MR imaging was also noted.


RESULTS
There were 151 patients whose median age was 60 (22-85) years. The EC MRA was abnormal in 56.3% and the IC MRA in 63.3% of patients, the internal carotid artery being the most common site. Corresponding infarct was present in 64.7% and noncorresponding in 45.3% of patients. The MRA abnormality positively correlated with hypertension and diabetes, and negatively with alcohol consumption. The EC MRA abnormality was more common in upper caste Hindus and Muslims and in the city dwellers.


CONCLUSIONS
In North Indian patients with IS, the frequency of EC and IC MRA abnormality lies between Whites and the Orientals.
Kumar
Gyanendra
G
Department of Neurology, University of Missouri-Health Care Columbia, Columbia, MO, USA.
Kalita
Jayantee
J
Kumar
Bishwanath
B
Bansal
Vikas
V
Jain
Sunil K
SK
Misra
UshaKant
U
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D001786:Blood Glucose / Q000502:physiology; D015992:Body Mass Index; D002545:Brain Ischemia / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D002342:Carotid Artery, External / Q000473:pathology* / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000473:pathology* / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000453:epidemiology; D005247:Feeding Behavior; D005260:Female; D005492:Folic Acid / Q000032:analysis / Q000097:blood; D006710:Homocysteine / Q000032:analysis / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007194:India / Q000453:epidemiology; D008055:Lipids / Q000032:analysis / Q000097:blood; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D044469:Racial Groups; D012307:Risk Factors; D012959:Socioeconomic Factors; D020521:Stroke / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D014805:Vitamin B 12 / Q000032:analysis / Q000097:blood; D055815:Young Adult
D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids; D006710:Homocysteine; D005492:Folic Acid; D014805:Vitamin B 12