Gold nanoparticle self-similar chain structure organized by DNA origami.
Here we demonstrate Au nanoparticle self-similar chain structure organized by triangle DNA origami with well-controlled orientation and <10 nm spacing. We show for the first time that a large DNA complex (origami) and multiple AuNP conjugates can be well-assembled and purified with reliable yields. The assembled structure could be used to generate high local-field enhancement. The same method can be used to precisely localize multiple components on a DNA template for potential applications in nanophotonic, nanomagnetic, and nanoelectronic devices.
Ding
Baoquan
B
Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA. BDing@lbl.gov
Deng
Zhengtao
Z
Yan
Hao
H
Cabrini
Stefano
S
Zuckermann
Ronald N
RN
Bokor
Jeffrey
J
D004247:DNA / Q000737:chemistry*; D004587:Electrophoresis, Agar Gel; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology / Q000379:methods; D009690:Nucleic Acid Conformation; D013056:Spectrophotometry, Ultraviolet
D006046:Gold; D004247:DNA