Cavernous angioma associated with arteriovenous malformation of the brain--case report.
A 61-year-old man presented a rare case of cerebral cavernous angioma associated with cerebral arteriovenous malformation (AVM) manifesting as headache. Magnetic resonance imaging showed an AVM in the right occipital lobe and a cavernous angioma in the left middle fossa. The patient underwent left frontotemporal craniotomy with total resection of the left parasellar intra-axial tumor. One month after the first operation, he underwent right occipital craniotomy with total resection of the right occipital AVM. The histological diagnoses were cavernous angioma and AVM, respectively. Immunostaining for angiogenic growth factors and structural proteins revealed different expression patterns of alpha-smooth muscle actin in these structures. Expression of structural proteins may reflect differences in their pathogenesis.
Kamiyama
Hironaga
H
Department of Neurosurgery, Aomori Prefectural Central Hospital, Aomori. hironaga@med.u-toyama.ac.jp
Nishimura
Shinjitsu
S
Kaimori
Mitsuhiro
M
Watanabe
Mika
M
Furuno
Yuichi
Y
Saito
Atsushi
A
Nishijima
Michiharu
M
D042501:Angiogenic Proteins / Q000032:analysis / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D002533:Cerebral Angiography; D002941:Circle of Willis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003399:Craniotomy; D006261:Headache / Q000209:etiology / Q000503:physiopathology; D020786:Hemangioma, Cavernous, Central Nervous System / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D009778:Occipital Lobe / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D020769:Posterior Cerebral Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D019292:Skull Base Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
D042501:Angiogenic Proteins; D014408:Biomarkers, Tumor