title: [Arteriosclerotic risk factors and benign prostatic hyperplasia].
abstract: OBJECTIVE
  To evaluate the correlation between arteriosclerotic risk factors and the severity of benign prostatic hyperplasia (BPH).
  
  
  METHODS
  A total of 877 patients with diagnosed BPH were selected according to the inclusion criteria. The weight of the prostate was estimated by transrectal ultrasonography, the degree of bladder outlet obstruction determined by urodynamic examination, and the symptoms quantified by the International Prostate Symptom Score (IPSS). Arteriosclerotic risk factors included age, hypertension, dyslipidemia, type 2 diabetes mellitus, and smoking. Comparative studies were made on the data obtained by univariate and multivariate analyses.
  
  
  RESULTS
  The severity of BPH was increased with the increase in the severity of the risk factors and the incidence of the disease. The logistic regression analysis showed that type 2 diabetes mellitus was a prominent predictor of the prostate volume, IPSS and degree of bladder outlet obstruction (OR = 3.179, 3.862 and 2.847, P < 0.001), while the level of serum triglyceride was not (P > 0.05). Age, hypertension, high LDL, low HDL and smoking were all prominent predictors of the severity of BPH.
  
  
  CONCLUSIONS
  Arteriosclerotic risk factors are obviously correlated with the development and severity of BPH, among which type 2 diabetes mellitus is the most important.
authors.affiliation: Department of Urology, Guangzhou General Hospital of Guangzhou Military Region, Guangzhou, Guangdong 510010, China. shenxiwen27@hotmail.com
authors.forename: Wen
authors.initials: W
authors.lastname: Shen
authors.forename: Hua-Qiang
authors.initials: HQ
authors.lastname: Yao
authors.forename: Zhi-Xiong
authors.initials: ZX
authors.lastname: Deng
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Zhang
authors.forename: Li-Chao
authors.initials: LC
authors.lastname: Zhang
authors.forename: Wei-Lie
authors.initials: WL
authors.lastname: Hu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000473:pathology*; D003924:Diabetes Mellitus, Type 2 / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000473:pathology*; D012307:Risk Factors; D001748:Urinary Bladder Neck Obstruction / Q000473:pathology