title: The relationship between depression and smoking cessation outcomes in treatment-seeking substance abusers.
abstract: The National Drug Abuse Treatment Clinical Trials Network (CTN) recently completed a randomized, open label trial comparing treatment as usual (TAU) combined with nicotine patches plus cognitive behavioral group counseling for smoking cessation (n = 153) to TAU alone (n = 72) for patients enrolled in treatment programs for drug or alcohol dependence, who were interested in quitting smoking. This report is a secondary analysis evaluating the effect of depressive symptomatology (n = 70) or history of depression (n = 110) on smoking cessation outcomes. A significant association was seen between measures of depression and difficulty quitting cigarettes. Specifically, there was a greater probability for smoking abstinence for those with lower baseline Beck Depression Inventory II (BDI-II) scores. These data suggest that evaluation and treatment of depressive symptoms may play an important role in improving smoking cessation outcomes. (Am J Addict 2010;00:1-8).
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA. sonnesc@musc.edu
authors.forename: Susan C
authors.initials: SC
authors.lastname: Sonne
authors.forename: Edward V
authors.initials: EV
authors.lastname: Nunes
authors.forename: Huiping
authors.initials: H
authors.lastname: Jiang
authors.forename: Clare
authors.initials: C
authors.lastname: Tyson
authors.forename: John
authors.initials: J
authors.lastname: Rotrosen
authors.forename: Malcolm S
authors.initials: MS
authors.lastname: Reid
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D016739:Behavior, Addictive / Q000150:complications / Q000188:drug therapy / Q000628:therapy; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D003865:Major Depressive Disorder / Q000150:complications* / Q000523:psychology; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006801:Humans; D008297:Male; D009538:Nicotine / Q000008:administration & dosage; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D011615:Psychotherapy, Group; D016540:Smoking Cessation / Q000523:psychology*; D019966:Substance-Related Disorders / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D009538:Nicotine