title: Metathesis Cascade Strategies (ROM-RCM-CM): A DOS approach to Skeletally Diverse Sultams.
abstract: The development of a ring-opening metathesis/ring-closing metathesis/cross metathesis (ROM-RCM-CM) cascade strategy to the synthesis of a diverse collection of bi- and tricyclic sultams is reported. In this study, functionalized sultam scaffolds derived from intramolecular Diels-Alder (IMDA) reactions undergo metathesis cascades to yield a collection tricyclic sultams. Additional appendage based diversity was achieved by utilizing a variety of CM partners.
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582.
authors.forename: Kyu Ok
authors.initials: KO
authors.lastname: Jeon
authors.forename: Dinesh
authors.initials: D
authors.lastname: Rayabarapu
authors.forename: Alan
authors.initials: A
authors.lastname: Rolfe
authors.forename: Kelly
authors.initials: K
authors.lastname: Volp
authors.forename: Iman
authors.initials: I
authors.lastname: Omar
authors.forename: Paul R
authors.initials: PR
authors.lastname: Hanson