Common HBV genotype in southeastern Iranian patients.
Asymptomatic hepatitis B infection is characterized as a type of hepatitis in which hepatitis B surface antigen is present in the patient's peripheral blood despite the absence of clinical symptoms. Previous studies have shown that a particular genotype may effect clinical manifestations of hepatitis B infection; hence, the aim of the current study was to determine the frequency of hepatitis B virus genotypes among asymptomatic carriers of hepatitis B.In this experimental study, the plasma samples of 100 asymptomatic carriers were collected and tested for HBsAg and anti-HBs using ELISA. The genotype of hepatitis B virus was determined by the GAP-PCR technique. The results of this study showed that all samples were positive for hepatitis B surface antigen and anti-hepatitis B core antigen was present in 60 (60%) cases. Our results also indicated that all patients had the D genotype of hepatitis B virus.
Eftekhari
Yahya
Y
Department of Microbiology, Hematology, and Immunology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Kazemi Arababadi
Mohammad
M
Hakimi
Hamid
H
Rezazadeh Zarandi
Ebrahim
E
D058070:Asymptomatic Diseases / Q000453:epidemiology; D004279:DNA, Viral / Q000235:genetics; D005838:Genotype; D006509:Hepatitis B / Q000453:epidemiology / Q000821:virology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics*; D006801:Humans; D007492:Iran / Q000453:epidemiology
D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens