title: Tremor: a newly described adverse event with long-term itraconazole therapy.
abstract: Itraconazole is a widely prescribed triazole antifungal drug, often given for long periods. The authors report five cases of tremor related to itraconazole therapy, which occurred within 1-12 months of initiating treatment and resolved gradually following itraconazole withdrawal.
authors.affiliation: Department of Transitional Medicine, The University of Manchester, Manchester, UK. jodi.lestner@postgrad.manchester.ac.uk
authors.forename: Jodi M
authors.initials: JM
authors.lastname: Lestner
authors.forename: David W
authors.initials: DW
authors.lastname: Denning
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000009:adverse effects* / Q000493:pharmacokinetics / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000097:blood / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000009:adverse effects* / Q000493:pharmacokinetics / Q000627:therapeutic use; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000097:blood / Q000188:drug therapy*; D055732:Pulmonary Aspergillosis / Q000097:blood / Q000188:drug therapy*; D014202:Tremor / Q000097:blood / Q000139:chemically induced*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole