title: Value of CT enteroclysis in suspected small-bowel carcinoid tumors.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the value of CT enteroclysis in depicting small-bowel carcinoid tumors in symptomatic patients with surgical, histologic, or clinical follow-up findings as a reference standard.
  
  
  METHODS
  At our institution, 44 patients with symptoms of suspected gastrointestinal carcinoid tumors underwent CT enteroclysis. Clinical symptoms were as follows: carcinoid syndrome (n = 3), abdominal pain with diarrhea (n = 24), hypervascular liver metastases (n = 7), subileus condition (n = 1), hypervascular peritoneal lesion (n = 3), abnormal ileal stenosis on optical colonoscopy (n = 3), and follow-up extraintestinal carcinoid lesion (n = 3). Positive CT enteroclysis findings were compared with pathology results after surgical procedures (n = 19). Negative examinations were compared with surgery results (n = 3) or clinical follow-up (n = 22).
  
  
  RESULTS
  CT enteroclysis findings were positive in 19 patients and negative in 25 patients. The sizes of the carcinoid tumors identified were 5-30 mm in axial diameter. These tumors were depicted as focal nodular lesions located in the small-bowel wall or as intraluminal polypoid masses with marked enhancement. Twenty-two patients underwent only clinical follow-up, with a mean clinical follow-up time of 20 months. The overall sensitivity and specificity of CT enteroclysis in identifying patients with small-bowel carcinoid tumors were 100% and 96.2%, respectively. The negative predictive value of CT enteroclysis was 100% and the positive predictive value, 94.7%. Pathologic findings confirmed small-bowel carcinoid tumors in 18 patients.
  
  
  CONCLUSIONS
  CT enteroclysis should be considered an excellent tool for the diagnosis of the carcinoid tumor before any surgical procedures.
authors.affiliation: Department of Gastrointestinal Radiology, Hôpital Edouard Herriot, 5 Place d'Arsonval, 69003 Lyon, France. kamaouiimane@yahoo.fr
authors.forename: Imane
authors.initials: I
authors.lastname: Kamaoui
authors.forename: Valeria
authors.initials: V
authors.lastname: De-Luca
authors.forename: Sabine
authors.initials: S
authors.lastname: Ficarelli
authors.forename: Nicolas
authors.initials: N
authors.lastname: Mennesson
authors.forename: Catherine
authors.initials: C
authors.lastname: Lombard-Bohas
authors.forename: Frank
authors.initials: F
authors.lastname: Pilleul
mesh_terms: D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D007421:Intestine, Small / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011857:Radiographic Image Interpretation, Computer-Assisted; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*