title: Localized hepatosplenic sarcoidosis with an elevated serum CA-125 level.
abstract: Sarcoidosis, a granulomatous disorder of unknown etiology, primarily affects the lungs and lymph nodes. Extrapulmonary disease without any pulmonary involvement is rare. Sarcoidosis with an elevated serum CA-125 level has only been reported five times in the literature. We describe a case of localized hepatosplenic sarcoidosis, confirmed by biopsy, with associated CA-125 elevation. In our review of the current literature, this is the first reported case of localized hepatosplenic sarcoidosis with associated serum CA-125 elevation.
authors.affiliation: Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Ramin S
authors.initials: RS
authors.lastname: Herati
authors.forename: Joyce M
authors.initials: JM
authors.lastname: Koh
authors.forename: Emmanuel C
authors.initials: EC
authors.lastname: Gorospe
mesh_terms: D018394:CA-125 Antigen / Q000097:blood*; D006801:Humans; D008107:Liver Diseases / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012507:Sarcoidosis / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D018394:CA-125 Antigen