Cobalt(II)-catalyzed intramolecular C-H amination with phosphoryl azides: formation of 6- and 7-membered cyclophosphoramidates.
A highly effective Co(II)-based system has been developed for catalytic intramolecular C-H amination with phosphoryl azides without the need of terminal oxidant or other additives, resulting in the high-yielding production of cyclophosphoramidates with nitrogen gas as the byproduct. Additional features of this new catalytic system include the amination of primary C-H bonds and formation of 7-membered-ring structures.
Lu
Hongjian
H
Department of Chemistry, University of South Florida, Tampa, Florida 33620-5250, USA.
Tao
Jingran
J
Jones
Jess E
JE
Wojtas
Lukasz
L
Zhang
X Peter
XP
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010756:Phosphoric Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000577:Amides; D001386:Azides; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; D010756:Phosphoric Acids; D003035:Cobalt; C011067:phosphoramidic acid