[Ion channelopathies and inherited arrhythmia].
Ion channelopathies are the mainly etiopathogenisis of inherited arrhythmia. Those arrhythmia syndromes are commonly caused by ion channel gene mutation, which can be classified as sodium,potassium and calcium ion channel mutation.Changes in the genes encoding for cardiac ion channel subunits produce modification in the function of the channels, and cause the dysfunctions of cardiac electrical activity; and the clinical manifestation is malignant arrhythmia.
Feng
Ming-jun
MJ
Ninbo First Hospital, Affiliated Medical of Ninbo University, Ninbo, China.
Chu
Hui-min
HM
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000235:genetics* / Q000503:physiopathology; D053447:Channelopathies / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D007473:Ion Channels / Q000235:genetics* / Q000502:physiology; D009154:Mutation
D007473:Ion Channels