Targeting the degradation of cyclin D1 will help to eliminate oncogene addiction.
Lee
James T
JT
Institute for Cancer Genetics, and Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Shan
Jing
J
Gu
Wei
W
D000818:Animals; D019938:Cyclin D1 / Q000235:genetics / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism; D016193:G1 Phase; D051379:Mice; D009369:Neoplasms / Q000628:therapy; D009857:Oncogenes; D016196:S Phase; D064570:Ubiquitin-Specific Proteases; D054875:Ubiquitination
D019938:Cyclin D1; D010450:Endopeptidases; D064570:Ubiquitin-Specific Proteases