title: Copper-catalyzed chlorination of functionalized arylboronic acids.
abstract: A mild, efficient, Cu(I)-catalyzed method for the conversion of arylboronic acids to aryl chlorides is reported. This method is particularly useful for the conversion of electron-deficient arylboronic acids to aryl chlorides, a transformation that is inefficient in the absence of Cu catalysis.
authors.affiliation: Discovery Chemistry, Bristol-Myers Squibb Company, PO Box 4000, Princeton New Jersey 08543, USA.
authors.forename: Hong
authors.initials: H
authors.lastname: Wu
authors.forename: John
authors.initials: J
authors.lastname: Hynes
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D006843:Hydrocarbons, Chlorinated; D003300:Copper