title: [Dravet syndrome].
abstract: Dravet syndrome is an epileptic syndrome of infancy and early childhood. Most cases of Dravet syndrome seem to be due to a genetic defect causing the sodium channel to malfunction. We describe the main features of the syndrome. This epilepsy is medically intractable, but we call attention to the fact that some medications are of benefit and some could exacerbate the condition. Early recognition of the syndrome including by genetic testing could possibly improve outcome and reduce the need for other specialized investigations.
authors.affiliation: Odense Universitetshospital, H.C. Andersen Børnehospital, DK-5000 Odense C, Denmark. lars.kjaersgaard@dadlnet.dk
authors.forename: Lars Kjaersgård
authors.initials: LK
authors.lastname: Hansen
authors.forename: Niels Henrik
authors.initials: NH
authors.lastname: Rasmussen
authors.forename: Lilian Bomme
authors.initials: LB
authors.lastname: Ousager
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D002675:Child, Preschool; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D004831:Epilepsies, Myoclonic / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics; D006801:Humans; D007223:Infant; D011379:Prognosis; D003294:Seizures, Febrile / Q000175:diagnosis; D015222:Sodium Channels / Q000235:genetics; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D015222:Sodium Channels