Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma.
Radiation therapy is a significant risk factor for the development of angiosarcoma. With the increase in breast conservation treatment, the incidence of cutaneous radiation-induced angiosarcoma of the breast is rising. If the angiosarcoma demonstrates epithelioid features, the tumor cells may present a diagnostic dilemma on fine-needle aspiration cytology. We present a case of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver and a review of the literature.
Park
Ji-Weon
JW
Department of Cytopathology, New York University, New York, USA. Ji-Weon.Park@nyumc.org
Serafica-Karen
Chantal
C
Das
Kasturi
K
D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000378:metabolism / Q000556:secondary; D002278:Carcinoma in Situ / Q000532:radiotherapy / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000532:radiotherapy / Q000601:surgery; D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D005260:Female; D006394:Hemangiosarcoma / Q000378:metabolism / Q000556:secondary; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000378:metabolism / Q000556:secondary*; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000378:metabolism / Q000473:pathology*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology