title: Divergent selection in trailing- versus leading-edge populations of Biscutella laevigata.
abstract: OBJECTIVE
  Knowledge on how climate-induced range shifts might affect natural selection is crucial to understand the evolution of species ranges.
  
  
  METHODS
  Using historical demographic perspectives gathered from regional-scale phylogeography on the alpine herb Biscutella laevigata, indirect inferences on gene flow and signature of selection based on AFLP genotyping were compared between local populations persisting at the trailing edge and expanding at the leading edge.
  
  
  RESULTS
  Spatial autocorrelation revealed that gene flow was two times more restricted at the trailing edge and genome scans indicated divergent selection in this persisting population. In contrast, no pattern of selection emerged in the expanding population at the leading edge.
  
  
  CONCLUSIONS
  Historical effects may determine different architecture of genetic variation and selective patterns within local populations, what is arguably important to understand evolutionary processes acting across the species ranges.
authors.affiliation: National Center for Biosystematics (NCB), Natural History Museum, University of Oslo, 0318 Oslo, Norway. christian.parisod@unine.ch
authors.forename: Christian
authors.initials: C
authors.lastname: Parisod
authors.forename: Stéphane
authors.initials: S
authors.lastname: Joost
mesh_terms: D054458:Amplified Fragment Length Polymorphism Analysis; D019607:Brassicaceae / Q000235:genetics*; D056426:Genetic Loci / Q000235:genetics; D005828:Genetics, Population; D018745:Genome, Plant / Q000235:genetics; D005838:Genotype; D011157:Population Dynamics; D012641:Selection, Genetic / Q000235:genetics*