title: [Lichen sclerosus and Turner syndrome].
abstract: Lichen sclerosus was diagnosed at a young age (19, 22 and 37 years) in three women with Turner syndrome. The oldest of these patients had probably suffered from this disorder for over 20 years. The relatively young age of these three patients is remarkable. This observation also suggests an increased frequency of lichen sclerosus among women with Turner syndrome. Immunological and hormonal factors might explain this association. Early detection of lichen sclerosus is important, as malignant transformation into carcinoma of the vulva may occur. It is advisable to perform regular gynaecological examination as part of the recommended periodic screening of adult women with Turner syndrome.
authors.affiliation: Universitair Medisch Centrum Groningen, Afd. Endocrinologie, Groningen, The Netherlands.
authors.forename: Mèlanie N
authors.initials: MN
authors.lastname: van Ijsselmuiden
authors.forename: Annelies M E
authors.initials: AM
authors.lastname: Bos
authors.forename: Annemieke
authors.initials: A
authors.lastname: Hoek
authors.forename: André P
authors.initials: AP
authors.lastname: van Beek
authors.forename: Michiel N
authors.initials: MN
authors.lastname: Kerstens
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D015995:Prevalence; D014424:Turner Syndrome / Q000453:epidemiology*; D007724:Vulvar Lichen Sclerosus / Q000175:diagnosis* / Q000453:epidemiology*; D055815:Young Adult