Recurrent ptosis due to myopathy of the levator palpebrae superioris.
The authors report the 10-year follow-up of a case with a recurrent ptosis affecting both eyelids independently. The histology of the levator palpebrae superioris and Müller's muscle was consistent with a localised myopathic process. A therapeutic response to acetazolamide suggests that ion-channel dysfunction may be the underlying cause for this new myopathy.
Petzold
A
A
UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. a.petzold@ion.ucl.ac.uk
Luthert
P J
PJ
Collin
J R O
JR
Plant
G T
GT
D000086:Acetazolamide / Q000627:therapeutic use; D001763:Blepharoptosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D005141:Eyelid Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009135:Muscular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide