title: Comparison of venous plasma glycemia and capillary glycemia for the screening of type 2 diabetes mellitus in the Japanese-Brazilian community of Mombuca (Guatapará-SP).
abstract: BACKGROUND
  To identify the most appropriate cut-off points of fasting glycemia for the screening of diabetes mellitus type 2 (DM2) with the comparison of the properties of capillary glycemia (CG) and venous blood plasma glycemia (PG) in a population of Japanese origin from the community of Mombuca, Guatapará-SP, Brazil.
  
  
  METHODS
  This was a population-based descriptive cross-sectional study conducted on a sample of 131 individuals of both genders aged 20 years or more (66.8% of the target population). CG was measured with a glucometer in a blood sample obtained from the fingertip and PG was determined by an enzymatic method (hexokinase) in venous blood plasma, after a 10-14 hour fast in both cases. Data were analyzed by the receiver operating characteristic (ROC) curve in order to identify the best cut-off point for fasting glycemia (CG and PG) for the diagnosis of DM, using the 2-hour plasma glycemia > 200 mg/dl as gold - standard.
  
  
  RESULTS
  The ROC curve revealed that the best cut-off point for the screening of DM was 110 mg/dl for CG and 105 mg/dl for PG, values that would optimize the relation between individuals with positive and false-positive results. The area under the ROC curve was 0.814 for CG (p < 0.01) and 0.836 for PG (p < 0.01).
  
  
  CONCLUSIONS
  The cut-off points of 105 mg/dl(5.8 mmol/l) for PG and of 110 mg/dl(6.1 mmol/l) for CG appear to be the most appropriate for the screening of DM2 in the population under study, with emphasis on the fact that the value recommended for CG is 5 mg/dl higher than that for PG, in contrast to WHO recommendations.
authors.affiliation: Departamento de Clinica Médica, Faculdade de Medicina de Ribeirão Preto-USP, Avenida Bandeirantes 3900, Ribeirão Preto-SP, Brazil. crisfoss@fmrp.usp.br
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Foss-Freitas
authors.forename: Regina C G
authors.initials: RC
authors.lastname: de Andrade
authors.forename: Roberta C
authors.initials: RC
authors.lastname: Figueiredo
authors.forename: Ana Emília
authors.initials: AE
authors.lastname: Pace
authors.forename: Edson Z
authors.initials: EZ
authors.lastname: Martinez
authors.forename: Amaury L
authors.initials: AL
authors.lastname: Dal Fabro
authors.forename: Laércio J
authors.initials: LJ
authors.lastname: Franco
authors.forename: Milton C
authors.initials: MC
authors.lastname: Foss