title: Super-harmonic imaging: development of an interleaved phased-array transducer.
abstract: For several years, the standard in ultrasound imaging has been second-harmonic imaging. A new imaging technique dubbed "super-harmonic imaging" (SHI) was recently proposed. It takes advantage of the higher - third to fifth - harmonics arising from nonlinear propagation or ultrasound-contrast-agent (UCA) response. Next to its better suppression of near-field artifacts, tissue SHI is expected to improve axial and lateral resolutions resulting in clearer images than second-harmonic imaging. When SHI is used in combination with UCAs, a better contrast-to-tissue ratio can be obtained. The use of SHI implies a large dynamic range and requires a sufficiently sensitive array over a frequency range from the transmission frequency up to its fifth harmonic (bandwidth > 130%). In this paper, we present the characteristics and performance of a new interleaved dual frequency array built chiefly for SHI. We report the rationale behind the design choice, frequencies, aperture, and piezomaterials used. The array is efficient both in transmission and reception with well-behaved transfer functions and a combined -6-dB bandwidth of 144%. In addition, there is virtually no contamination of the harmonic components by spurious transducer transmission, due to low element-to-element crosstalk (< 30 dB) and a low transmission efficiency of the odd harmonics (< 46 dB). The interleaved array presented in this article possesses ideal characteristics for SHI and is suitable for other methods like second-harmonic, subharmonic, and second-order ultrasound field (SURF) imaging.
authors.affiliation: Department of Biomedical Engineering, Erasmus Medical Centre, Rotterdam, The Netherlands. p.vanneer@erasmusmc.nl
authors.forename: Paul L M J
authors.initials: PL
authors.lastname: van Neer
authors.forename: Guillaume
authors.initials: G
authors.lastname: Matte
authors.forename: Mikhail G
authors.initials: MG
authors.lastname: Danilouchkine
authors.forename: Christian
authors.initials: C
authors.lastname: Prins
authors.forename: Franc
authors.initials: F
authors.lastname: van den Adel
authors.forename: Nico
authors.initials: N
authors.lastname: de Jong
mesh_terms: D003198:Computer Simulation; D003287:Contrast Media; D015150:Echocardiography, Doppler / Q000295:instrumentation* / Q000379:methods*; D017711:Nonlinear Dynamics; D016011:Normal Distribution; D014159:Transducers
chemical_list: D003287:Contrast Media