Mental disorders in Mexican patients with multiple sclerosis.
The authors aim to explore psychiatric disorders in Mexican patients with multiple sclerosis. The Structured Clinical Interview for DSM-IV Axis I Disorders, the Montgomery-Asberg Depression Rating Scale, and the Hamilton Anxiety Rating Scale were administered to 37 consecutive multiple sclerosis patients and 37 healthy comparison subjects. The multiple sclerosis group had higher rates of any axis I disorder (OR 1.97; 95% CI=1.78-3.306). The most common comorbid diagnoses were depressive disorders (46% of the multiple sclerosis cases) with higher anxiety scores (p=0.001). No correlations between psychiatric variables, number of relapses, and clinical course of multiple sclerosis were found.
Espinola-Nadurille
Mariana
M
Research Department and Neuropsychiatric Unit, National Institute of Neurology and Neurosurgery of Mexico, Mexico City, Mexico.
Colin-Piana
Ricardo
R
Ramirez-Bermudez
Jesus
J
Lopez-Gomez
Mario
M
Flores
Jose
J
Arrambide
Georgina
G
Corona
Teresa
T
D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D015995:Prevalence; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires