Anesthetic management of a patient with an allergy to propylene glycol and parabens.
Multiple pharmaceutical products contain excipients, or additive chemicals, to improve stability, bioavailability, antimicrobial activity, or palatability. Two of the most common excipients are propylene glycol and parabens. We report the successful anesthetic management of a patient with idiosyncratic reactions to prescribed and over-the-counter medications containing propylene glycol and parabens.
Farber
Michaela K
MK
Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Angelo
Tiffany E
TE
Castells
Mariana
M
Tsen
Lawrence C
LC
D000328:Adult; D000698:Analgesia; D000768:Anesthesia, General; D000775:Anesthesia, Spinal; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005079:Excipients / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007428:Intradermal Tests; D007889:Leiomyoma / Q000601:surgery*; D010226:Parabens / Q000009:adverse effects*; D019946:Propylene Glycol / Q000009:adverse effects*; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000601:surgery*
D005079:Excipients; D010226:Parabens; D019946:Propylene Glycol