title: Expeditious Enyne Construction from Alkynes via Oxidative Pd(II) Catalyzed Heck-Type Coupling.
abstract: The enyne, ubiquitous in natural products, can be a challenge to generate since these moieties require many synthetic transformations to assemble them. We developed a simpler protocol to construct enynes while we found that this oxidative reaction was tolerant in substrate scope. In addition, the utility of this reaction was demonstrated through the attempt in synthesizing antifungal agent Lamisi.
authors.affiliation: Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, CA 90089-1661.
authors.forename: Victor
authors.initials: V
authors.lastname: Hadi
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Yoo
authors.forename: Min
authors.initials: M
authors.lastname: Jeong
authors.forename: Kyung Woon
authors.initials: KW
authors.lastname: Jung