title: Total synthesis of haouamine A: the indeno-tetrahydropyridine core.
abstract: A full account of synthetic efforts towards the indeno-tetrahydropyridine core of haouamine A is presented. Initial failed strategies led to the unexpected discovery of a mild abnormal Chichibabin pyridine synthesis and provided knowledge and inspiration for the development of a cascade annulation that has enabled rapid and scalable access to the core in either racemic or enantiopure form.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Noah Z
authors.initials: NZ
authors.lastname: Burns
authors.forename: Mikkel
authors.initials: M
authors.lastname: Jessing
authors.forename: Phil S
authors.initials: PS
authors.lastname: Baran