title: Central corneal thickness, anterior chamber depth, and pupil diameter measurements using Visante OCT, Orbscan, and Pentacam.
abstract: OBJECTIVE
  To evaluate the agreement among three different optical methods in measuring anterior chamber depth (ACD), central corneal thickness (CCT), and pupil diameter.
  
  
  METHODS
  One hundred eyes of 50 healthy patients (25 men, 25 women) were enrolled in the study. Mean patient age was 25 years (range: 21 to 32 years). Exclusion criteria were history of any intraocular or corneal surgery, contact lens wear, corneal anomalies, and spherical refraction >5.00 diopters (D) or cylindrical refraction >2.00 D. All measurements were done by the same operator under mesopic light conditions and repeated using three different optical methods: Visante optical coherence tomography (OCT) (Carl Zeiss Meditec), Orbscan (Bausch & Lomb), and Pentacam (Oculus Optikgeräte GmbH).
  
  
  RESULTS
  Mean CCT as measured by Visante OCT, Orbscan, and Pentacam was 529+/-30.5 microm, 554+/-32.7 microm, and 552+/-29.3 microm, respectively. Mean ACD values were 2.94+/-0.34 mm, 2.84+/-0.33 mm, and 2.98+/-0.33 mm, respectively. Mean pupil diameter measurements were 4.87+/-1.09 mm, 4.0+/-0.67 mm, and 3.05+/-0.59 mm, respectively. The Visante OCT measured CCT thinner and Orbscan measured ACD shallower than the other two methods. All three methods measured pupil diameters significantly different.
  
  
  CONCLUSIONS
  This study found some statistically significant but clinically insignificant differences among the optical methods assessed. The differences are small and do not influence decisions for refractive surgery in clinical practice.
authors.affiliation: Beyoglu Eye Research and Training Hospital, Istanbul, Turkey.
authors.forename: Ahmet Taylan
authors.initials: AT
authors.lastname: Yazici
authors.forename: Ercument
authors.initials: E
authors.lastname: Bozkurt
authors.forename: Cengiz
authors.initials: C
authors.lastname: Alagoz
authors.forename: Nese
authors.initials: N
authors.lastname: Alagoz
authors.forename: Gokhan
authors.initials: G
authors.lastname: Pekel
authors.forename: Vedat
authors.initials: V
authors.lastname: Kaya
authors.forename: Omer Faruk
authors.initials: OF
authors.lastname: Yilmaz
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000033:anatomy & histology*; D000886:Anthropometry; D001699:Biometry; D003315:Cornea / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007368:Interferometry / Q000379:methods*; D008027:Light; D008297:Male; D010781:Photography / Q000379:methods*; D011680:Pupil; D012016:Reference Values; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult