title: [Case of ischemic heart disease resulting from persistent diuresis after giant ovarian tumor resection].
abstract: A patient with a giant ovarian tumor weighing about 7 kg was successfully removed by operation. However, her ECG demonstrated ischemic changes after the operation. We report a case of ischemic heart disease due to persistent diuresis after giant ovarian tumor resection. A 75-year-old, 56.5 kg, 143.5 cm woman was admitted to our hospital for ovarian tumor resection. The preoperative ECG showed normal sinus rhythm and no ischemic changes. Both general anesthesia and epidural anesthesia were planed. An epidural catheter was inserted at T12-L1. Anesthesia was induced with propofol 100 mg, fentanyl 100 microg and vecuronium 8 mg under 100% oxygen inhalation. General anesthesia was maintained with sevoflurane while epidural anesthesia was achieved using 0.375% ropivacaine 6 ml. During the operation, blood pressure was 90-110/70-80 mmHg, with SaO2, 100% and heart rate, 70-80 beats x min(-1). The content of tumor was suctioned for 30 minutes. Surgery was successfully finished without any other incidence. After extubation, her ECG changed to atrial fibrillation from normal sinus rhythm and showed ST-T depression. And then her systolic blood pressure became 80 mmHg or below, but we found continued diuresis at about 10 ml x kg(-1) x hr(-1) for over 2 hr. The total of 7 unit vasopressin was intermittently given for vasoconstriction and antidiuresis. Her hemodynamic was immediately restored, and ECG turned to normal ST-T. The patient had uneventful postoperative recovery.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Shimotsuke 329-0498.
authors.forename: Naho
authors.initials: N
authors.lastname: Sata
authors.forename: Masaaki
authors.initials: M
authors.lastname: Satoh
authors.forename: Norimasa
authors.initials: N
authors.lastname: Seo
mesh_terms: D000368:Aged; D000767:Anesthesia, Epidural; D000768:Anesthesia, General; D050034:Antidiuretic Agents / Q000008:administration & dosage; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000188:drug therapy; D004231:Diuresis; D004562:Electrocardiography; D005260:Female; D006801:Humans; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy; D010051:Ovarian Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome; D014555:Urination Disorders / Q000652:urine; D014667:Vasopressins / Q000008:administration & dosage
chemical_list: D050034:Antidiuretic Agents; D014667:Vasopressins