title: [Arbovirus eco-epidemiology in the area affected by the Cuiabá-Santarém Highway (BR-163), Pará State, Brazil].
abstract: The current study describes the eco-epidemiological aspects of arbovirus diseases in the municipalities (counties) of Novo Progresso and Trairão, Para State, Brazil, in the area affected by highway BR-163. Hemagglutination inhibition (HI) antibodies to different arboviruses were detected, with monotypic reactions to MAYV and OROV, two important arboviruses associated with epidemics in the Amazon. IgM antibodies to OROV and MAYV were found in human sera, suggesting recent infections by these viruses. Two DENV-3 strains were isolated from febrile patients in Novo Progresso and identified as genotype III strains. In general, the data suggest that the area displays ideal conditions for maintenance and circulation of arboviruses, plus a population with low immunization levels. Dynamic surveillance of local immigrants and wild animals is thus important, focusing on antibody prevalence and isolation of arboviruses, thereby allowing effective control of infections by these viral agents in the resident population along highway BR-163 in Pará State.
authors.affiliation: Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Ananindeua, PA, Brazil. marcionunes@iec.pa.gov.br
authors.forename: Marcio Roberto Teixeira
authors.initials: MR
authors.lastname: Nunes
authors.forename: Taciana Fernandes Souza
authors.initials: TF
authors.lastname: Barbosa
authors.forename: Lívia Medeiros Neves
authors.initials: LM
authors.lastname: Casseb
authors.forename: Joaquim Pinto
authors.initials: JP
authors.lastname: Nunes Neto
authors.forename: Nazaré de Oliveira
authors.initials: Nde O
authors.lastname: Segura
authors.forename: Hamilton Antônio de Oliveira
authors.initials: HA
authors.lastname: Monteiro
authors.forename: Eliana Vieira
authors.initials: EV
authors.lastname: Pinto
authors.forename: Samir Mansour
authors.initials: SM
authors.lastname: Casseb
authors.forename: Jannifer de Oliveira
authors.initials: Jde O
authors.lastname: Chiang
authors.forename: Lívia Caricio
authors.initials: LC
authors.lastname: Martins
authors.forename: Daniele Barbosa de Almeida
authors.initials: DB
authors.lastname: Medeiros
authors.forename: Pedro Fernando da Costa
authors.initials: PF
authors.lastname: Vasconcelos
mesh_terms: D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001102:Arbovirus Infections / Q000453:epidemiology* / Q000662:veterinary* / Q000821:virology; D001103:Arboviruses / Q000276:immunology*; D001179:Arthropod Vectors / Q000821:virology; D001938:Brazil / Q000453:epidemiology; D004196:Disease Outbreaks; D004199:Disease Vectors; D017753:Ecosystem; D004784:Environmental Monitoring / Q000706:statistics & numerical data*; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D013045:Species Specificity; D014507:Urbanization
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M