title: Urinary bladder botryoid rhabdomyosarcoma with widespread metastases in an 8-month-old Labrador cross dog.
abstract: An 8-month-old crossbred Labrador retriever was presented with a history and clinical signs suggestive of lower urinary tract obstruction. Laboratory results revealed azotaemia and hyperphosphataemia. Ultrasonographic evaluation of the urinary tract showed a mass at the bladder trigone, hydronephrosis, hyrodureter, and suspected metastases to lymph nodes and the liver. Pulmonary metastasis was identified on thoracic radiographs. A post mortem confirmed metastases to the liver, lungs and regional lymph nodes, as well as to the mesenteric lymph nodes, mediastinum, heart, subcutaneous tissue and several muscle groups. A histopathological diagnosis of metastatic botryoid rhabdomyosarcoma (sarcoma botryoides) was made. A review of the literature shows that, although the bladder trigone is a well documented location for this tumour, this case was unique with its widespread metastases to previously undocumented organs. The incidence, embryology, ultrasonographic appearance and treatment of this tumour are discussed.
authors.affiliation: kgerbervet@gmail.com
authors.forename: K
authors.initials: K
authors.lastname: Gerber
authors.forename: P
authors.initials: P
authors.lastname: Rees
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D008113:Liver Neoplasms / Q000556:secondary / Q000662:veterinary; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000662:veterinary*; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000662:veterinary*