title: [Non-heart-beating-donor transplant: the first experience in Italy].
abstract: A promising way to increase the number of kidneys for transplantation is to expand the donor pool by including non-heart-beating donors (NHBDs). The centers involved in NHBD transplantation programs have reported a 16-40% increase in kidney transplants. A key issue with NHBD is the significantly higher rate of delayed graft function (DGF) and primary non-function (PNF) compared with that associated with heart-beating donor (HBD) transplants. However, although transplants from NHBD are associated with a greater incidence of early adverse events, long-term graft survival appears to be similar to that observed after transplants from HBDs. In addition, the use of extracorporeal membrane oxygenation and mechanical perfusion, the careful selection of recipients and donors, and an adequate therapeutic strategy may at least partially reduce the risk of PNF and DGF and improve transplant outcome.
authors.affiliation: Unità di Nefrologia, Dialisi e Trapianto, Fondazione IRCCS Policlinico San Matteo e Università degli Studi, Pavia. t.rampino@smatteo.pv.it
authors.forename: Teresa
authors.initials: T
authors.lastname: Rampino
authors.forename: Massimo
authors.initials: M
authors.lastname: Abelli
authors.forename: Elena
authors.initials: E
authors.lastname: Ticozzelli
authors.forename: Marilena
authors.initials: M
authors.lastname: Gregorini
authors.forename: Francesca
authors.initials: F
authors.lastname: Bosio
authors.forename: Giovanni
authors.initials: G
authors.lastname: Piotti
authors.forename: Giulia
authors.initials: G
authors.lastname: Bedino
authors.forename: Pasquale
authors.initials: P
authors.lastname: Esposito
authors.forename: Chiara Teresa
authors.initials: CT
authors.lastname: Balenzano
authors.forename: Paolo
authors.initials: P
authors.lastname: Geraci
authors.forename: Antonio
authors.initials: A
authors.lastname: Dal Canton
mesh_terms: D001926:Brain Death; D051799:Delayed Graft Function; D006085:Graft Survival; D006323:Heart Arrest; D006801:Humans; D007558:Italy; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000401:mortality; D009926:Organ Preservation / Q000379:methods; D012307:Risk Factors; D013997:Time Factors; D020858:Tissue and Organ Harvesting; D009927:Tissue and Organ Procurement / Q000379:methods*; D016896:Treatment Outcome