Case of localized scleroderma associated with osteomyelitis.
We report a 4-year-old girl presenting with progressive linear scleroderma affecting the right leg. Biopsy specimen disclosed typical histopathological findings of localized scleroderma. Right leg magnetic resonance imaging (MRI) showed high signal areas on T(2)-weighted images on the subcutaneous fatty tissue, muscles and bone marrow, suggesting that skin inflammation extended to the bone marrow. Oral corticosteroid therapy was instituted with improvement of both skin sclerosis and MRI findings. Our observations suggest that MRI examination should be considered in patients with localized scleroderma to evaluate the extension of the inflammation.
Muroi
Eiji
E
Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Ogawa
Fumihide
F
Yamaoka
Toshifumi
T
Sueyoshi
Fumiko
F
Sato
Shinichi
S
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000974:Antibodies, Antinuclear / Q000097:blood; D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007866:Leg; D008279:Magnetic Resonance Imaging; D010019:Osteomyelitis / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D012594:Scleroderma, Localized / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology
D000305:Adrenal Cortex Hormones; D000974:Antibodies, Antinuclear