title: [Adaptation of a soft-signs scale to children with autism spectrum disorders].
abstract: BACKGROUND
  Neurological soft signs (NSS) are endophenotypic markers of schizophrenia, and their high prevalence in pervasive developmental disorders (PDD) support the existence of the spectrum of psychoses. These NSS were evaluated by standardized scales which were not adapted to children with PDD.
  
  
  OBJECTIVE
  This study aimed to propose an adaptation for children of a scale of NSS already used in adults.
  
  
  METHODS
  21 children with PDD (11 with autistic disorder, 10 with PDD not otherwise specified) aged 6-12 years and 21 controls matched on age, sex, and cognitive level were included. Evaluating tools were NSS scale of Krebs et al. adapted after a pilot-study with the accordance of its author; the Progressive Matrices of Raven for intellectual level, and ADI-R to confirm diagnosis.
  
  
  RESULTS
  Patients were significantly more impaired on total score (p=0,001), motor coordination (p=0,008), motor integration (p=0,000), and sensory integration (p=0,001). There were no difference between patients and controls on abnormal movements and quality of lateralization.
  
  
  CONCLUSIONS
  This adaptation of Krebs et al. scale seems to be a good tool for evaluating NSS in children, especially in those with PDD. A further validation study, including a larger sample is necessary.
authors.affiliation: Unité de recherche Processus cognitifs dans la pathologie psychiatrique, Service de Psychiatrie B, Hôpital Razi, La Manouba.
authors.forename: Soumeyya
authors.initials: S
authors.lastname: Halayem
authors.forename: Asma
authors.initials: A
authors.lastname: Bouden
authors.forename: Isabelle
authors.initials: I
authors.lastname: Amado
authors.forename: Marie-Odile
authors.initials: MO
authors.lastname: Krebs
authors.forename: Karim
authors.initials: K
authors.lastname: Tabbane
authors.forename: Mohamed
authors.initials: M
authors.lastname: Halayem
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000503:physiopathology*; D002658:Developmental Disabilities / Q000503:physiopathology*; D006801:Humans; D009483:Neuropsychological Tests