title: Vestibular evoked myogenic potentials in patients with fibromyalgia syndrome.
abstract: OBJECTIVE
  To assess vestibular evoked myogenic potentials in patients with fibromyalgia syndrome.
  
  
  METHODS
  Twenty-four patients with fibromyalgia syndrome (two men and 22 women) and 21 female controls were included in the study. All patients underwent vestibular evoked myogenic potential testing.
  
  
  RESULTS
  Statistical comparison of fibromyalgia patients with control subjects showed a significant difference with respect to n23 latencies and interpeak latencies (p < 0.05). There was no significant difference in p13 latencies, nor in p13 amplitudes, n23 amplitudes or interpeak amplitudes (p > 0.05).
  
  
  CONCLUSIONS
  Although patients with fibromyalgia syndrome generally have subjective neurotological symptoms, clinical and laboratory assessments usually fail to detect any objective abnormality. However, it is possible to detect abnormalities on vestibular evoked myogenic potential testing in such patients, indicating dysfunction in the vestibulospinal pathway, possibly in the saccule. Elongation of the n23 latency and of the interpeak latency of waves p13-n23, during vestibular evoked myogenic potential testing, may be a useful, objective indicator demonstrating neurotological involvement in fibromyalgia syndrome patients. Future research investigating the mechanisms of this latency elongation may help increase understanding of the pathogenesis of fibromyalgia syndrome.
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Gazi University, Besevler, Cankaya, Ankara, Turkey. bayazity@yahoo.com
authors.forename: Yildirim A
authors.initials: YA
authors.lastname: Bayazit
authors.forename: F
authors.initials: F
authors.lastname: Celenk
authors.forename: A G
authors.initials: AG
authors.lastname: Gunduz
authors.forename: B
authors.initials: B
authors.lastname: Gunduz
authors.forename: N
authors.initials: N
authors.lastname: Ondag
authors.forename: J
authors.initials: J
authors.lastname: Meray
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004576:Electromyography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D005356:Fibromyalgia / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology; D011930:Reaction Time; D014724:Vestibular Function Tests / Q000379:methods; D014722:Vestibule, Labyrinth / Q000502:physiology*; D055815:Young Adult