title: Biochemically responsive smart surface.
abstract: A design of smart surfaces responsive to biochemical analytes is demonstrated in the example of mixed monolayers of biotin/fluorocarbon. The contact angle of aqueous solutions on such surfaces decreases upon streptavidin binding and can be used in detecting this protein. The specificity of the effect is confirmed by the lack of a contact angle change by streptavidin blocked with biotin and by bovine serum albumin.
authors.affiliation: Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA.
authors.forename: Fabian
authors.initials: F
authors.lastname: Rios
authors.forename: Sergei
authors.initials: S
authors.lastname: Smirnov
mesh_terms: D000327:Adsorption; D001672:Biocompatible Materials / Q000737:chemistry*; D001710:Biotin / Q000737:chemistry*; D008422:Materials Testing; D011485:Protein Binding; D019809:Streptavidin / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D001710:Biotin; D019809:Streptavidin