Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation and coagulation and ameliorates renal fibrin deposition in a rat model of acute renal failure.
Spek
C Arnold
CA
Brüggemann
Lois W
LW
Borensztajn
Keren S
KS
D058186:Acute Kidney Injury / Q000188:drug therapy*; D000818:Animals; D004195:Disease Models, Animal; D004731:Endotoxins; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy*; D008070:Lipopolysaccharides; D010455:Peptides / Q000627:therapeutic use*; D051381:Rats; D044464:Receptor, PAR-2 / Q000037:antagonists & inhibitors* / Q000276:immunology
D004731:Endotoxins; D008070:Lipopolysaccharides; D010455:Peptides; D044464:Receptor, PAR-2