Cyclic sulfamidates as vehicles for the synthesis of poly- and diversely substituted benzosultams via unusual S(O)2-O bond cleavage.
1,2-Cyclic sulfamidates undergo novel, efficient, and regiospecific intramolecular nucleophilic cleavage with aryllithiated species to provide an entry to poly-, diversely, and enantiopure N-substituted benzosultams.
Lorion
Magali
M
Univ Lille Nord de France, F-59000 Lille, France.
Agouridas
Vangelis
V
Couture
Axel
A
Deniau
Eric
E
Grandclaudon
Pierre
P
D003500:Cyclization; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry*; D013458:Sulfur Dioxide / Q000737:chemistry*
D013449:Sulfonamides; D013458:Sulfur Dioxide; D010100:Oxygen