title: Asymmetric synthesis of (2S,3R)-(-)-epi-CP-99,994 using sulfinimine-derived anti-2,3-diamino esters.
abstract: A differentially protected C-3 N-sulfinyl, C-2 N,N-(diphenylmethylene) 2,3-diamino ester was employed in the synthesis of the amino piperidine (2S,3R)-(-)-epi-CP-99,994. Key steps in the synthesis included the chemoselective hydrolysis of the C-2 N,N-(diphenylmethylene) group and its reprotection as a dibenzylamino group.
authors.affiliation: Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States.
authors.forename: Franklin A
authors.initials: FA
authors.lastname: Davis
authors.forename: Yanfeng
authors.initials: Y
authors.lastname: Zhang