An Efficient Boric Acid Mediated Preparation of α-Hydroxyamides.
An efficient methodology for the preparation of α-hydroxyamides via boric acid mediated addition of isonitriles on to aldehydes has been developed. The reaction of isonitriles with α-boronobenzaldehyde takes place under intramolecular catalysis conditions to provide functionalized benzoxaboroles.
Kumar
J Sravan
JS
Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN 55812.
Jonnalagadda
Subash C
SC
Mereddy
Venkatram R
VR