title: Organization and physiology of posterior lateral line afferent neurons in larval zebrafish.
abstract: The lateral line system of larval zebrafish can translate hydrodynamic signals from the environment to guide body movements. Here, I demonstrate a spatial relationship between the organization of afferent neurons in the lateral line ganglion and the innervation of neuromasts along the body. I developed a whole cell patch clamp recording technique to show that afferents innervate multiple direction-sensitive neuromasts, which are sensitive to low fluid velocities. This work lays the foundation to integrate sensory neuroscience and the hydrodynamics of locomotion in a model genetic system.
authors.affiliation: The Whitney Laboratory for Marine Bioscience-Department of Biology, St Augustine, FL, USA. jliao@whitney.ufl.edu
authors.forename: James C
authors.initials: JC
authors.lastname: Liao
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D007814:Larva / Q000033:anatomy & histology / Q000502:physiology; D008954:Models, Biological; D009043:Motor Activity / Q000502:physiology; D009420:Nervous System / Q000033:anatomy & histology; D009424:Nervous System Physiological Phenomena; D009475:Neurons, Afferent / Q000502:physiology* / Q000648:ultrastructure; D018408:Patch-Clamp Techniques; D013550:Swimming / Q000502:physiology; D015027:Zebrafish / Q000033:anatomy & histology* / Q000502:physiology