Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus.
A 40-year-old woman with no major medical illness except for morbid obesity (BMI 40.7) was admitted to our hospital because of bilateral pneumonia due to a novel swine-origin influenza A (H1N1) virus (S-OIV). Non-invasive ventilation was introduced because of the hypoxemia. The description of bronchoalveolar lavage fluid findings showed an alveolar hemorrhage and neutrophilic inflammation. No evidence of bacterial infection was found. She was treated with oseltamivir and sivelestat sodium, neutrophil elastase inhibitor and thereafter was successfully discharged from the hospital. This case is the first report of a patient with acute lung injury with an alveolar hemorrhage caused by the S-OIV.
Yokoyama
Toshiki
T
The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto.
Tsushima
Kenji
K
Ushiki
Atsuhito
A
Kobayashi
Nobumitsu
N
Urushihata
Kazuhisa
K
Koizumi
Tomonobu
T
Kubo
Keishi
K
D055371:Acute Lung Injury / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D005998:Glycine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006470:Hemorrhage / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000472:pathogenicity*; D007251:Influenza, Human / Q000150:complications / Q000188:drug therapy; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D053139:Oseltamivir / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use; D016896:Treatment Outcome
D000998:Antiviral Agents; D013449:Sulfonamides; D053139:Oseltamivir; C069195:sivelestat; D005998:Glycine