title: Pd(II)-catalyzed ortho-trifluoromethylation of arenes using TFA as a promoter.
abstract: A Pd(II)-catalyzed C-H activation/trifluoromethylation of arenes with an electrophilic trifluoromethylation reagent using diverse heterocycle directing groups is reported. The presence of trifluoroacetic acid is crucial for this catalytic reaction.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Xisheng
authors.initials: X
authors.lastname: Wang
authors.forename: Larry
authors.initials: L
authors.lastname: Truesdale
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D001554:Benzene / Q000737:chemistry*; D002384:Catalysis; D005025:Ethylene Dichlorides / Q000737:chemistry; D008745:Methylation; D010165:Palladium / Q000737:chemistry*; D014269:Trifluoroacetic Acid / Q000737:chemistry*
chemical_list: D005025:Ethylene Dichlorides; D010165:Palladium; D014269:Trifluoroacetic Acid; D001554:Benzene