Hyperprolactinaemia in early psychosis-not only due to antipsychotics.
Hyperprolactinaemia is often found in patients with schizophrenia and usually considered a consequence of antipsychotics. Prolactin levels were measured in 43 At-Risk Mental State individuals (ARMS) and 26 patients with First Episode Psychosis (FEP). Hyperprolactinaemia was found in 25.6% of ARMS and 46.2% of FEP. Within 60 antipsychotic-naïve ARMS and FEP, hyperprolactinaemia was found in 26.7%. Hyperprolactinaemia may be pre-existing in a subgroup of patients with schizophrenia.
Aston
Jacqueline
J
Psychiatric University Outpatient Department, Psychiatric University Clinics Basel, c/o University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland.
Rechsteiner
Evelyne
E
Bull
Nadine
N
Borgwardt
Stefan
S
Gschwandtner
Ute
U
Riecher-Rössler
Anita
A
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000209:etiology*; D007118:Immunoassay / Q000379:methods; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy; D008609:Mental Status Schedule; D011388:Prolactin / Q000097:blood; D012737:Sex Factors; D055815:Young Adult
D014150:Antipsychotic Agents; D011388:Prolactin