Evidence for sensory neuropathy and pharmacologic management.
Recent literature points to postviral sensory neuropathy as a possible cause for refractory chronic cough. Vagal neuropathy may affect the sensory branches, inducing chronic cough or laryngospasm. Although the clinical presentation is fairly well described, there is little in the way of diagnostic criteria to establish this diagnosis. This article highlights the clinical picture of this disease and the efficacy, side-effect profiles of the currently used pharmacological interventions.
Greene
Scott M
SM
Department of Otolaryngology-Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Simpson
C Blake
CB
D018759:Adrenergic Uptake Inhibitors / Q000627:therapeutic use; D000588:Amines / Q000627:therapeutic use; D000639:Amitriptyline / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002908:Chronic Disease; D003371:Cough / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D000077206:Gabapentin; D006801:Humans; D000069583:Pregabalin; D020421:Vagus Nerve Diseases / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D014777:Virus Diseases / Q000150:complications; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives / Q000627:therapeutic use
D018759:Adrenergic Uptake Inhibitors; D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D000639:Amitriptyline; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin