title: Interruption of physical activity because of illness in the Lifestyle Interventions and Independence for Elders Pilot trial.
abstract: OBJECTIVE
  To examine baseline characteristics and change in gait speed and Short Physical Performance Battery (SPPB) scores in participants medically suspended (MS) from a physical activity intervention (PA).
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  University and community centers.
  
  
  METHODS
  Sedentary older adults (N = 213) randomized to PA in the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P).
  
  
  METHODS
  MS was defined as missing 3 consecutive PA sessions in adoption and transition phases or 2 wk in maintenance phase because of a health event.
  
  
  RESULTS
  In all, 122 participants completed PA without MS (NMS subgroup), 48 participants underwent MS and resumed PA (SR subgroup), and 43 participants underwent MS and did not complete PA (SNR subgroup). At baseline, SNR walked slower (p = .03), took more prescribed medications (p = .02), and had lower SPPB scores than NMS and SR (p = .02). Changes from baseline to Month 12 SPPB scores were affected by suspension status, adjusted mean (SE) SPPB change: SNR 0.0957 (0.3184), SR 0.9413 (0.3063), NMS 1.0720 (0.1871); p = .03.
  
  
  CONCLUSIONS
  MS participants unable to return to complete the PA in a trial of mobility-limited sedentary older adults had slower walking speeds, lower SPPB scores, and a higher number of prescribed medications at baseline. Change in SPPB scores at 12 months was related to suspension status.
authors.affiliation: Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Tufts University, Boston, MA, USA.
authors.forename: Edward M
authors.initials: EM
authors.lastname: Phillips
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Katula
authors.forename: Michael E
authors.initials: ME
authors.lastname: Miller
authors.forename: Michael P
authors.initials: MP
authors.lastname: Walkup
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Brach
authors.forename: Abby C
authors.initials: AC
authors.lastname: King
authors.forename: W Jack
authors.initials: WJ
authors.lastname: Rejeski
authors.forename: Tim
authors.initials: T
authors.lastname: Church
authors.forename: Roger A
authors.initials: RA
authors.lastname: Fielding
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003863:Depression / Q000453:epidemiology; D004185:Disability Evaluation; D005260:Female; D005684:Gait; D015577:Geriatric Assessment; D006293:Health Promotion; D006304:Health Status; D006801:Humans; D008019:Life Style; D008297:Male