title: Limb salvage for soft-tissue sarcomas of the foot and ankle.
abstract: We evaluated the oncological and functional outcome of 27 patients who had limb salvage for a soft-tissue sarcoma of the foot or ankle between 1992 and 2007, with a mean follow-up of 7.5 years (1.05 to 16.2). There were 12 men and 15 women, with a mean age at presentation of 47 years (12 to 84). Referrals came from other hospitals for 16 patients who had previous biopsy or unplanned excision, and 11 presented de novo. There were 18 tumours located in the foot and nine around the ankle. Synovial sarcoma was the most frequent histological diagnosis. Excision was performed in all cases, with 16 patients requiring plastic surgical reconstruction with 13 free and three local flaps. Adjuvant treatment was undertaken in 20 patients, 18 with radiotherapy and two by chemotherapy. Limb salvage was successful in 26 of the 27 patients. There have been two local recurrences and two mesenchymal metastases. Four patients have died of their sarcoma and two of other causes. Function was evaluated with the Toronto Extremity Salvage Score and a mean overall score of 89.40 (52.1 to 100) was obtained. A questionnaire revealed that all surviving patients are able to wear normal shoes and none require a walking aid. Limb salvage can achieve good oncological and functional results with additional treatment.
authors.affiliation: Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry SY10 7AG, UK. gilliancribb@me.com
authors.forename: G L
authors.initials: GL
authors.lastname: Cribb
authors.forename: S C S
authors.initials: SC
authors.lastname: Loo
authors.forename: I
authors.initials: I
authors.lastname: Dickinson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000842:Ankle; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005534:Foot Diseases / Q000534:rehabilitation / Q000628:therapy*; D006801:Humans; D023821:Limb Salvage / Q000379:methods* / Q000534:rehabilitation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods; D020127:Recovery of Function; D012509:Sarcoma / Q000534:rehabilitation / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000534:rehabilitation / Q000628:therapy*; D013524:Surgical Flaps; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult