Gold(I)-catalyzed synthesis of (1E,3E)-dienes from propargylic esters.
A mild and stereoselective gold(I)-catalyzed domino transformation of propargylic esters leading to substituted (1E,3E)-dienes has been developed. This cascade process proceeds via a sequence of 1,3-acyloxy- or 1,3-phosphatyloxy migrations to form allenic intermediate followed by a proton transfer.
Dudnik
Alexander S
AS
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7061, USA.
Schwier
Todd
T
Gevorgyan
Vladimir
V