Organization and physiology of posterior lateral line afferent neurons in larval zebrafish.
The lateral line system of larval zebrafish can translate hydrodynamic signals from the environment to guide body movements. Here, I demonstrate a spatial relationship between the organization of afferent neurons in the lateral line ganglion and the innervation of neuromasts along the body. I developed a whole cell patch clamp recording technique to show that afferents innervate multiple direction-sensitive neuromasts, which are sensitive to low fluid velocities. This work lays the foundation to integrate sensory neuroscience and the hydrodynamics of locomotion in a model genetic system.
Liao
James C
JC
The Whitney Laboratory for Marine Bioscience-Department of Biology, St Augustine, FL, USA. jliao@whitney.ufl.edu
D000818:Animals; D001696:Biomechanical Phenomena; D007814:Larva / Q000033:anatomy & histology / Q000502:physiology; D008954:Models, Biological; D009043:Motor Activity / Q000502:physiology; D009420:Nervous System / Q000033:anatomy & histology; D009424:Nervous System Physiological Phenomena; D009475:Neurons, Afferent / Q000502:physiology* / Q000648:ultrastructure; D018408:Patch-Clamp Techniques; D013550:Swimming / Q000502:physiology; D015027:Zebrafish / Q000033:anatomy & histology* / Q000502:physiology