[Controversies and future of the approach to cardiovascular disease in HIV patients].
Cardiovascular diseases are an increasing problem in patients with HIV infection. The causes of the increased cardiovascular risk in HIV-infected patients are multifactorial. Currently, the question of which factor has the most weight in this equation - whether traditional risk factors, the virus per se or antiretroviral therapy - remains to be determined. The absolute risk of cardiovascular disease in a particular patient depends on the composite risk profile. At present, there are no data to support a distinct approach to cardiovascular risk evaluation in HIV-infected patients. Cardiovascular risk equations should be incorporated into routine daily clinical assessment in order to identify patients in need of specific interventions.
Bernardino de la Serna
José Ignacio
JI
Unidad VIH, Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, España. jibernardino.hulp@salud.madrid.org
Arribas López
José Ramón
JR
D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D001161:Arteriosclerosis / Q000453:epidemiology / Q000209:etiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015331:Cohort Studies; D015897:Comorbidity; D016207:Cytokines / Q000378:metabolism; D004198:Disease Susceptibility; D005544:Forecasting; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D006949:Hyperlipidemias / Q000139:chemically induced / Q000453:epidemiology; D007249:Inflammation / Q000188:drug therapy / Q000453:epidemiology; D007333:Insulin Resistance; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors
D019380:Anti-HIV Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D016207:Cytokines