title: Nadroparine-induced skin necrosis on a patient with essential thrombocythaemia: a case report.
abstract: Skin necrosis is a rare but serious complication of subcutaneously administered low-molecular-weight heparin. We report a case of a 53-year-old female patient with skin necrosis induced by subcutaneous administration of nadroparine. The patient suffered from essential thrombocythaemia on a background of chronic myeloproliferative disease. She was admitted to our clinic with a subacute ileus due to endometriosis of the rectosigmoid junction. She underwent a high anterior resection and she received pre- and postoperative antithrombotic prophylaxis with subcutaneous nadroparine on a daily basis. On the 6th and 7th postoperative days, two skin necroses occurred at two injection sites.
authors.affiliation: Department of Surgery, European Medical Center, Asklipiou 10, 57001 Thessaloniki, Greece. mpramateftakis@hotmail.com
authors.forename: Manousos-Georgios
authors.initials: MG
authors.lastname: Pramateftakis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Kanellos
authors.forename: Stefanos
authors.initials: S
authors.lastname: Psomas
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kanellos