title: Anal transitional zone adenocarcinoma following restorative proctocolectomy for ulcerative colitis: case report and review of literature.
abstract: Conservative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the intervention of choice for severe ulcerative colitis (UC) requiring surgery. Sporadically, the occurrence of carcinoma arising in or near the ileo-anal pouch after IPAA for UC has been reported. This issue is of utmost importance as an endoscopic follow-up is mandatory also after the operation. The present paper reports a case of cancer which developed four years after proctocolectomy with IPAA in a young man suffering from UC. Moreover, the authors provide update (PubMed research) by literature review on this issue.
authors.affiliation: 7th Department of Surgery, S Giovanni Battista (Molinette) Hospital, Turin, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Panier-Suffat
authors.forename: M
authors.initials: M
authors.lastname: Marracino
authors.forename: A
authors.initials: A
authors.lastname: Resegotti
authors.forename: M
authors.initials: M
authors.lastname: Astegiano
authors.forename: A
authors.initials: A
authors.lastname: Giustetto
authors.forename: M
authors.initials: M
authors.lastname: Garino
authors.forename: R
authors.initials: R
authors.lastname: Pellicano
authors.forename: G
authors.initials: G
authors.lastname: Fronda
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology*; D000328:Adult; D001005:Anus Neoplasms / Q000209:etiology*; D003093:Colitis, Ulcerative / Q000150:complications* / Q000601:surgery*; D039021:Colonic Pouches / Q000473:pathology*; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative / Q000379:methods; D017792:Surgical Stapling