title: Symptoms before, during, and 14 months after the beginning of treatment as perceived by patients with lymphoma.
abstract: OBJECTIVE
  To explore occurrence of symptoms and relationships between them as perceived by patients with lymphoma before, during, and 14 months after the beginning of treatment.
  
  
  METHODS
  Qualitative and longitudinal.
  
  
  METHODS
  A major oncology center in the United Kingdom.
  
  
  METHODS
  10 adult patients with lymphoma (3 women and 7 men) were recruited at treatment initiation.
  
  
  METHODS
  Semistructured audiotaped interviews were conducted with participants in median 15 days, 4 months, and 14 months after diagnosis. Analysis of the verbatim transcripts was inspired by interpretive description, which is a grounded approach articulating patterns emerging in relation to clinical phenomena.
  
  
  METHODS
  Symptoms.
  
  
  RESULTS
  Symptoms commonly reported by patients in this sample were lack of energy, lymphadenopathy, weight loss, itching, pain, sadness, night sweats, sleeping difficulties, and hair loss. Co-occurring prediagnosis symptoms seem to have led patients to seek medical attention; co-occurring symptoms during treatment seem to have a cumulatively distressing effect. Several of the symptoms were described as interrelated, with one symptom leading to one or more other symptoms.
  
  
  CONCLUSIONS
  The data confirm a complex symptomatology in patients with lymphoma. In addition, the findings support that co-occurring symptoms may have a synergistic effect on patients' health outcomes and add new knowledge about relationships between symptoms from patients' perspectives.
  
  
  CONCLUSIONS
  Illustrating symptoms and interrelationships between symptoms using diagrams may be useful to support communication as well as in identifying targets for symptom management.
authors.affiliation: Department of Medicine, Karolinska Institutet, Stockholm, Sweden. eva.mo.johansson@karolinska.se
authors.forename: Eva
authors.initials: E
authors.lastname: Johansson
authors.forename: Barbara
authors.initials: B
authors.lastname: Wilson
authors.forename: Lisa
authors.initials: L
authors.lastname: Brunton
authors.forename: Carol
authors.initials: C
authors.lastname: Tishelman
authors.forename: Alex
authors.initials: A
authors.lastname: Molassiotis
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001007:Anxiety / Q000451:nursing; D005221:Fatigue / Q000139:chemically induced* / Q000451:nursing*; D005260:Female; D006801:Humans; D007039:Hypotrichosis / Q000139:chemically induced / Q000451:nursing; D007407:Interviews as Topic; D008206:Lymphatic Diseases / Q000139:chemically induced / Q000451:nursing; D008223:Lymphoma / Q000188:drug therapy / Q000451:nursing / Q000523:psychology; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000139:chemically induced / Q000451:nursing; D009723:Nurse-Patient Relations; D009859:Oncology Nursing / Q000379:methods*; D010146:Pain / Q000139:chemically induced / Q000451:nursing; D012893:Sleep Wake Disorders / Q000139:chemically induced / Q000451:nursing; D012944:Social Support; D015431:Weight Loss; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents