Osteosarcoma radioinduced after adenoid cystic tumor of the parotid gland.
Osteosarcoma can develop secondary to malignant transformation within a preexisting benign bone lesion, such as Paget disease, osteonecrosis, fibrous dysplasia, and chronic infection, or it can arise in previously irradiated areas. This article presents the case of a 36-year-old woman who was affected by a radioinduced osteosarcoma after radiotherapy for an adenoid cystic carcinoma of the left parotid gland treated when she was 24 years old.
Belli
Evaristo
E
Department of Maxillo-Facial Surgery, II Faculty of Medicine and Surgery Sapienza University, Sant Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Mazzone
Noemi
N
Rendine
Guido
G
D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D035301:Cranial Fossa, Middle; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020360:Neoadjuvant Therapy; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000209:etiology*; D012516:Osteosarcoma / Q000209:etiology*; D010307:Parotid Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D019292:Skull Base Neoplasms / Q000209:etiology*