title: A Robust QTL Mapping Procedure.
abstract: In quantitative-trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are completely unspecified. Classical Wilcoxon-Mann-Whitney statistics are employed for point and interval estimation of QTL positions and effects.
authors.affiliation: Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599.
authors.forename: Fei
authors.initials: F
authors.lastname: Zou
authors.forename: Lei
authors.initials: L
authors.lastname: Nie
authors.forename: Fred A
authors.initials: FA
authors.lastname: Wright
authors.forename: Pranab K
authors.initials: PK
authors.lastname: Sen