The use of the American Society of Anesthesiology Classification as a prognostic factor in patients with renal cell carcinoma.
OBJECTIVE
We analyzed whether the American Society of Anesthesiology (ASA) classification could be used as a prognostic factor in renal cell carcinoma.


METHODS
ASA classification's impact on cancer-specific survival (CSS) and on overall survival in 145 patients submitted to radical or partial nephrectomy was evaluated, and was compared with clinicopathological variables.


RESULTS
CSS was influenced by ASA in uni- and multivariate analyses. Five-year CSS was 95.7, 71.1 and 39.8% for ASA 1, ASA 2 and ASA 3, respectively (p = 0.007). The ASA classification influenced the overall survival too (p < 0.001). When 18 patients with metastases were excluded, the CSS was 95.7, 83.9 and 42.9% for ASA 1, ASA 2 and ASA 3, respectively (p = 0.001). ASA 3 patients had ten times more metastases than ASA1 patients and two times more than ASA 2 patients (p = 0.001). ASA 3 patients had fewer incidental tumors (p = 0.043) than ASA 2 and 3 patients.


CONCLUSIONS
In this series, the ASA classification could be used as a prognostic factor in renal cell carcinoma.
de Cássio Zequi
Stênio
S
Service of Urology, Department of Pelvic Surgery, Hospital AC Camargo, São Paulo, Brazil. steniozequi@uol.com.br
de Campos
Eurico C R
EC
Guimarães
Gustavo C
GC
Bachega
Wilson
W
da Fonseca
Francisco P
FP
Lopes
Ademar
A
D000328:Adult; D000776:Anesthesiology / Q000379:methods; D002292:Carcinoma, Renal Cell / Q000145:classification / Q000175:diagnosis* / Q000401:mortality; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000401:mortality; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009362:Neoplasm Metastasis; D011379:Prognosis; D016016:Proportional Hazards Models; D013997:Time Factors; D016896:Treatment Outcome