Review: Carbon nanotube based electrochemical sensors for biomolecules.
Carbon nanotubes (CNTs) have been incorporated in electrochemical sensors to decrease overpotential and improve sensitivity. In this review, we focus on recent literature that describes how CNT-based electrochemical sensors are being developed to detect neurotransmitters, proteins, small molecules such as glucose, and DNA. Different types of electrochemical methods are used in these sensors including direct electrochemical detection with amperometry or voltammetry, indirect detection of an oxidation product using enzyme sensors, and detection of conductivity changes using CNT-field effect transistors (FETs). Future challenges for the field include miniaturizing sensors, developing methods to use only a specific nanotube allotrope, and simplifying manufacturing.
Jacobs
Christopher B
CB
Dept. of Chemistry, University of Virginia, PO Box 400319, Charlottesville, VA 22904, United States.
Peairs
M Jennifer
MJ
Venton
B Jill
BJ
D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis*; D004563:Electrochemistry / Q000379:methods*; D005947:Glucose / Q000032:analysis*; D036103:Nanotechnology / Q000379:methods; D037742:Nanotubes, Carbon / Q000737:chemistry*
D037742:Nanotubes, Carbon; D004247:DNA; D005947:Glucose