title: Self-folding cavitands: structural characterization of the induced-fit model.
abstract: Deletion of structural elements in cavitand receptors is used to evaluate the thermodynamic and kinetic parameters of binding in these hosts. The use of a bulky guest showcases the importance of host-guest shape adaptations in the molecular recognition process.
authors.affiliation: The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Agustí
authors.initials: A
authors.lastname: Lledó
authors.forename: Julius
authors.initials: J
authors.lastname: Rebek
mesh_terms: D004988:Ethers, Cyclic / Q000737:chemistry*; D006860:Hydrogen Bonding; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D012118:Resorcinols / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D004988:Ethers, Cyclic; D012118:Resorcinols; C442939:cavitand