title: Urine cytology in the evaluation of urological malignancy revisited: is it still necessary?
abstract: OBJECTIVE
  We aim to determine if urine cytology was still necessary as a routine part of the evaluation for the presence of urological malignancy and to evaluate its cost effectiveness.
  
  
  METHODS
  Urine cytology reports over a 6-year period (2000-2005) were retrieved from our institution's pathology department database. Patients with urine cytology positive for malignant cells were identified. We retrospectively reviewed the charts of these patients for age, sex, flexible cystoscopy and radiological imaging results. The cost of urine cytology was retrieved from the pathology department.
  
  
  RESULTS
  There were a total of 2,568 urine cytological examinations. Of these, 25 were positive for malignant cells. There were 19 male (76%) and 6 female (24%) patients with a mean age of 72 years (range: 49-97). In 21 patients with positive cytology, a bladder tumor was identified at flexible cystoscopy and/or imaging studies. For a positive cytology yield of 1%, EUR 210,000 was spent.
  
  
  CONCLUSIONS
  Routine urine cytology was not cost effective and did not add to the diagnostic yield beyond cystoscopy and diagnostic imaging. It may be omitted in the initial evaluation of urological malignancy.
authors.affiliation: Department of Urology, Mercy University Hospital, Glenville Place, Cork, Ireland. opefaleb@yahoo.com
authors.forename: Opeyemi Adegboyega
authors.initials: OA
authors.lastname: Falebita
authors.forename: Garry
authors.initials: G
authors.lastname: Lee
authors.forename: Paul
authors.initials: P
authors.lastname: Sweeney
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D003558:Cystoscopy / Q000379:methods; D005189:False Positive Reactions; D005260:Female; D006417:Hematuria / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000652:urine; D014572:Urology / Q000379:methods*