Correlation between semen analysis by motile sperm organelle morphology examination and sperm DNA damage.
Regression analysis of 538 semen samples demonstrated that percentages of normal nuclear sperm and all spermatozoa with abnormalities of nuclear form at high magnification had significant negative correlation with percentages of DNA fragmentation. On the other hand, there was a positive correlation between percentages of spermatozoa with nuclear vacuoles and those with DNA fragmentation.
Oliveira
Joao Batista Alcantara
JB
Center for Human Reproduction Prof Franco Junior, Ribeirao Preto, Brazil.
Massaro
Fabiana Cagnoto
FC
Baruffi
Ricardo Luis Razera
RL
Mauri
Ana Lúcia
AL
Petersen
Claudia Guilhermino
CG
Silva
Liliane F I
LF
Vagnini
Laura D
LD
Franco
José Gonçalves
JG
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure; D004249:DNA Damage; D053938:DNA Fragmentation; D006801:Humans; D007248:Infertility, Male / Q000473:pathology / Q000503:physiopathology; D008297:Male; D012044:Regression Analysis; D055101:Semen Analysis / Q000379:methods*; D013081:Sperm Motility / Q000502:physiology*; D013094:Spermatozoa / Q000502:physiology* / Q000648:ultrastructure*; D014617:Vacuoles / Q000648:ultrastructure