title: The application of the first order system transfer function for fitting the California Verbal Learning Test learning curve.
abstract: Very few attempts have been made to apply a mathematical model to the learning curve in the California Verbal Learning Test list A immediate recall. Our rationale was to find out whether modeling of the learning curve can add additional information to the standard CVLT [corrected] measures. We applied a standard transfer function in the form Y = B3*exp(-B2*(X-1))+B4*(1-exp(-B2*(X-1))), where X is the trial number; Y is the number of recalled correct words, B2 is the learning rate, B3 is readiness to learn and B4 is ability to learn. The coefficients of the model were found to be independent measures not duplicating standard CVLT [corrected] measures. Regression analysis revealed that readiness to learn (B3) and ability to learn (B4) were significantly (p < .05) higher in a group of healthy participants than in a group of participants with type 2 diabetes mellitus (T2DM), but the learning rate (B2) did not differ (p > .2). The proposed model is appropriate for clinical application and as a guide for research and may be used as a good supplemental tool for the CVLT [corrected] and similar memory tests.
authors.affiliation: Department of Neuropharmacology, Institute for Experimental Medicine, St. Petersburg 197376, Russia. igorstep@is12044.spb.edu
authors.forename: Igor I
authors.initials: II
authors.lastname: Stepanov
authors.forename: Charles I
authors.initials: CI
authors.lastname: Abramson
authors.forename: Oliver T
authors.initials: OT
authors.lastname: Wolf
authors.forename: Antonio
authors.initials: A
authors.lastname: Convit
mesh_terms: D000328:Adult; D000368:Aged; D001288:Attention; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008875:Middle Aged; D009483:Neuropsychological Tests; D014163:Transfer, Psychology; D014706:Verbal Learning