Inhaled epoprostenol during one-lung ventilation.
We used inhaled epoprostenol (with intravenous phenylephrine) during one-lung ventilation to improve oxygenation in a patient with severe interstitial lung disease undergoing video-assisted thoracoscopic surgery. The pharmacologic manipulation of pulmonary blood flow remains an underused strategy for the management of hypoxemia during one-lung ventilation.
Raghunathan
Karthik
K
Department of Anesthesiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA. karthik.raghunathan@bhs.org
Connelly
Neil Roy
NR
Robbins
Larry D
LD
Ganim
Rose
R
Hochheiser
Gary
G
DiCampli
Rebecca
R
D000280:Administration, Inhalation; D001706:Biopsy; D011464:Epoprostenol / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D008168:Lung / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D010656:Phenylephrine / Q000008:administration & dosage; D011652:Pulmonary Circulation / Q000187:drug effects; D012121:Respiration, Artificial / Q000379:methods*; D020775:Thoracic Surgery, Video-Assisted; D014665:Vasodilator Agents / Q000008:administration & dosage*
D014665:Vasodilator Agents; D010656:Phenylephrine; D011464:Epoprostenol