title: Giant villous adenoma presenting as McKittrick-Wheelock syndrome and pseudo-obstruction.
abstract: McKittrick-Wheelock syndrome is a rare but recognised complication of hypersecretory rectosigmoid villous adenoma. Fluid and electrolyte imbalances require close monitoring because of large-volume losses of water, sodium and potassium. We report an unusual presentation of the syndrome associated with the development of acute pseudo-obstruction of the colon, presumably due to electrolyte dysfunction and acute renal failure.
authors.affiliation: The Alfred Hospital, Melbourne, VIC, Australia. L.Miles@alfred.org.au
authors.forename: Lachlan F
authors.initials: LF
authors.lastname: Miles
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Wakeman
authors.forename: K Chip
authors.initials: KC
authors.lastname: Farmer
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D018253:Adenoma, Villous / Q000150:complications* / Q000175:diagnosis; D000368:Aged; D003110:Colonic Neoplasms / Q000150:complications* / Q000175:diagnosis; D003112:Colonic Pseudo-Obstruction / Q000175:diagnosis / Q000209:etiology*; D003113:Colonoscopy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014883:Water-Electrolyte Imbalance / Q000175:diagnosis / Q000209:etiology*