[Shenfu Qiangjing decoction improves non-inflammatory and non-liquefied semen in kidney-yang deficiency men].
OBJECTIVE
To observe the clinical efficacy of Shenfu Qiangjing Decoction (SQD) in the treatment of non-inflammatory and non-liquefied semen in infertile males with kidney-yang deficiency.


METHODS
Sixty cases of male infertility caused by non-inflammatory and non-liquefied semen with kidney-yang deficiency were equally and randomly divided into an SQD and a control group, the former given oral SQD and the latter vitamin C tablets plus intramuscular chymotrypsin. Both groups were observed for sperm viability, sperm motility, serum testosterone, seminal plasma PSA and improvement of kidney-yang deficiency symptoms before and after the medication. The therapeutic effects were evaluated according to the semen liquefaction within 60 min.


RESULTS
Statistically significant differences were observed in the improvement of kidney-yang deficiency symptoms after the medication between the SQD and control groups (P < 0.01, P < 0.05) , and in sperm viability and motility of the SQD group before and after the treatment (P < 0.01) as well as between the two groups after the medication (P < 0.05). The levels of serum T and seminal plasma PSA also showed significant differences before and after the treatment in the SQD group (P < 0.01) and between the two groups after the medication (P < 0.05). The rate of total effectiveness was 93.3% in the SQD and 76.7% in the control group (P < 0.05).


CONCLUSIONS
SQD can shorten the semen liquefaction time in patients with non-inflammatory and non-liquefied semen and restore semen liquefaction to normal in over 90% of the patients. Meanwhile it can also improve the low testosterone level resulting from various kidney-yang deficiency symptoms.
Xiong
Guo-Bao
GB
Reproductive Center, Affiliated Hospital of Nanchang Institute of Medical Sciences, Nanchang, Jiangxi 330001, China. xiongguobao1010@163.com
Yao
Wen-Liang
WL
Wu
Fei-Hua
FH
D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D008517:Phytotherapy; D055101:Semen Analysis; D013081:Sperm Motility; D016711:Yang Deficiency / Q000188:drug therapy*; D055815:Young Adult
D004365:Drugs, Chinese Herbal