The worst case: giant exulcerating seminoma.
Ten years after his brother had been treated for seminoma, a 36-year-old male presented with a giant exulcerating mass involving the right testis and both inguinal regions. Subsequent biopsy revealed pure seminoma. Staging computed tomography (CT) showed bulky retroperitoneal and pelvic lymph node metastases. After seven courses of cisplatin-based chemotherapy, positron emission tomography suggested residual tumor in the right groin. The suspicious lesion and the right testis were resected showing no vital tumor tissue. Eight months after surgery there were no signs of disease progression at follow-up CT.
Letsch
Markus
M
Department of Urology and Pediatric Urology, Julius Maximilians University Medical School, Oberdürrbacher Strasse 6, DE-97080 Würzburg, Germany. Letsch_M@klinik.uni-wuerzburg.de
Spahn
Martin
M
Beissert
Matthias
M
Topp
Max S
MS
Gerharz
Elmar W
EW
Riedmiller
Hubertus
H
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D018450:Disease Progression; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods; D018239:Seminoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D013737:Testis / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods
D000970:Antineoplastic Agents; D002945:Cisplatin