[Seizure and non-cardiogenic pulmonary edema after intoxication].
We report a case of severe intoxication with extended-release verapamil. In addition to cardiovascular toxicities with hypotension, atrioventricular block and bradycardia, the patient suffered from grand-mal seizure and pulmonary edema 13 and 48 hours respectively, after ingestion of 4.8 g of extended-release verapamil. Adverse reactions after intoxications with extended-release tablets appear delayed with prolonged manifestation of symptoms. Early and repetitive administration of activated charcoal and antegrade whole bowel lavage are crucial, even in primary asymptomatic patients.
Sawatzki
M
M
Medizinische Klinik, Universitätsspital Basel, Basel, Schweiz.
Kummer
O
O
Krähenbühl
S
S
Siegemund
M
M
D000328:Adult; D002318:Cardiovascular Diseases / Q000150:complications; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000175:diagnosis*; D012640:Seizures / Q000139:chemically induced* / Q000175:diagnosis*; D014700:Verapamil / Q000633:toxicity*
D014700:Verapamil