[Genital lymphogranuloma venereum in an HIV-1 infected patient].
BACKGROUND
Lymphogranuloma venereum (LGV) is an uncommon sexually transmitted disease caused by the L serovars of Chlamydiae trachomatis. Since 2003-2004, a continued outbreak of LGV proctitis (C. trachomatis serovar L2b) has been reported in North America and Europe, including France, among homosexual males, especially with HIV co-infection.


METHODS
A 41-year-old man presented penile ulceration of three weeks' standing, associated with a large swollen granulomatous lesion and an inguinal lymph node but without proctitis. All lesions resolved after a three-week course of doxycycline 200mg daily. These lesions were related to a genital bubo due to LGV as confirmed by positive specific PCR for C. trachomatis (serovar L2) performed on the genital ulceration.


CONCLUSIONS
Clinical descriptions of male genital LGV are infrequent, even during the LGV proctitis epidemic seen in Western countries in recent years. A diagnosis of LGV must be considered in the presence of sexually transmitted genital lesions, even atypical, especially among HIV-infected patients.
Flexor
G
G
Département de médecine aiguë, service des maladies infectieuses et tropicales, hôpital Raymond-Poincaré, AP-HP, université Versailles-Saint-Quentin, 104, boulevard R.-Poincaré, 92380 Garches, France.
Clarissou
J
J
Gaillet
M
M
de Barbeyrac
B
B
Perronne
C
C
de Truchis
P
P
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male
D000900:Anti-Bacterial Agents; D004318:Doxycycline