title: Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma.
abstract: OBJECTIVE
  To report two cases of persistent epitheliopathy after treatment of conjunctival melanoma and review management options for this condition.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  Persistent epitheliopathy, presumably resulting from limbal stem cell deficiency, is an uncommon complication of treatment of conjunctival malignant melanoma with surgical excision, cryotherapy, and mitomycin C. The Boston Ocular Surface Prosthesis was successful in improving vision, comfort, and epithelial status in our patients.
  
  
  CONCLUSIONS
  Persistent epitheliopathy is a rare complication of treatment of conjunctival melanoma. The Boston Ocular Surface Prosthesis is a viable treatment option in this situation.
authors.affiliation: Harvard Medical School, Boston, MA, USA.
authors.forename: Surbhi
authors.initials: S
authors.lastname: Grover
authors.forename: Deborah S
authors.initials: DS
authors.lastname: Jacobs
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Colby
mesh_terms: D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage; D001187:Artificial Organs; D003230:Conjunctival Neoplasms / Q000473:pathology / Q000601:surgery*; D003316:Corneal Diseases / Q000209:etiology / Q000601:surgery*; D019573:Epithelium, Corneal / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D011183:Postoperative Complications; D019736:Prostheses and Implants; D019919:Prosthesis Implantation
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin