[Image-guided percutaneous biopsy of gastric lesions with suspicion of malignancy and negative endoscopic biopsies: report of our experience and revision of the literature].
BACKGROUND
Endoscopic biopsy is the most efficient way to obtain a biopsy specimen from neoplastic lesions located in the stomach. Therefore, it is the procedure of choice to obtain a histologic diagnosis of gastric cancer. Image guided percutaneous biopsy is an alternative method to obtain histologic material for definitive diagnosis when the biopsies are negative for neoplastic cells in several endoscopies.


OBJECTIVE
The purpose of this study was to evaluate the efficacy, complications, and histologic results of image guided percutaneous biopsies of gastric lesions in our center.


METHODS
Between March 2004 and March 2007, 6 patients with strong suspicion of gastric cancer and negative endoscopic biopsies were referred for image guided percutaneous biopsy of gastric lesions (5 were guided by ultrasonography and 1 by CT scan).


RESULTS
A histologic diagnosis was made in 5 patients: poorly differentated signet-ring cell carcinoma 3, B-cell non-Hodgkin's lymphoma 2. One patient suffered a perforation during the procedure and the final histologic diagnosis was obtained after the consequent surgery (B-cell non-Hodgkin's lymphoma).


CONCLUSIONS
Despite of the scant published series, image guided percutaneous biopsy of gastric lesions is an useful, safe and effective technique to obtain a histologic diagnosis in patients with strong suspicion of gastric cancer and negative endoscopic biopsies.
Antelo
Marina
M
Residencia de Clínica Gastroenterológica, Hospital de Gastroenterología Dr Carlos Bonorino Udaondo, Buenos Aires, Argentina. machuantelo@hotmail.com
Castro
Lilian
L
Zamora
Víctor
V
Cabanne
Ana
A
Tanoue
Patricio
P
Corti
Rodolfo
R
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D005260:Female; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional / Q000379:methods; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D018084:Ultrasonography, Interventional / Q000379:methods