Simultaneous analysis of thiabendazole, carbendazim and 2-aminobenzimidazole in concentrated fruit juices by liquid chromatography after a single mix-mode solid-phase extraction cleanup.
A method using liquid chromatography and a single mix-mode solid-phase extraction cleanup for the simultaneous analysis of thiabendazole [2-(1,3-thiazol-4-yl)-1H-benzoimidazole], carbendazim [(methyl N-(1H-benzoimidazol-2-yl)-carbamate)] and 2-aminobenzimidazole (1H-benzimidazol-2-amine) in concentrated fruit juices is described. The three fungicides were isolated from the samples and concentrated by solid-phase extraction on Oasis MCX cartridges. The determination was performed by liquid chromatography with a diode array, detecting at 288 nm. In this method, the average recoveries from blank control juice samples spiked in a concentration range of 0.01-0.10 mg/kg were in the range of 81-95%, with relative standard deviations below 8%. Detection limits and limits of quantification were 4 micro g/kg and 10 micro g/kg, respectively, for each fungicide. Real juice samples were analyzed by the proposed method. The results were compared to those from liquid chromatography-tandem mass spectrometry.
Liu
Xiao S
XS
School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China. lxs3344@126.com
Tong
Zhang F
ZF
Zhen
Ling
L
Huang
Da X
da X
Gao
Xin
X
Xu
Chao Y
CY
D001562:Benzimidazoles / Q000032:analysis*; D001628:Beverages / Q000032:analysis*; D002219:Carbamates / Q000032:analysis*; D002853:Chromatography, Liquid; D005506:Food Contamination / Q000032:analysis; D005638:Fruit / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000032:analysis; D057230:Limit of Detection; D052616:Solid Phase Extraction; D013827:Thiabendazole / Q000032:analysis*
D001562:Benzimidazoles; D002219:Carbamates; D005659:Fungicides, Industrial; C027391:2-aminobenzimidazole; C006698:carbendazim; D013827:Thiabendazole