title: A platinum-chromium steel for cardiovascular stents.
abstract: The desire to reduce the strut thickness of cardiovascular stents has driven the development of a new high strength radiopaque alloy, based on additions of platinum to a chromium-rich iron based matrix. This paper reports on initial development of the alloy and the rationale for selection of the composition. Data is presented for tensile and microstructural characterization, surface oxide analysis, corrosion resistance and endothelial cell response of the alloy. The results demonstrate the solid solution strengthening effect of the platinum, with an average yield strength of 480 MPa achieved. The material surface consists of primarily chromium oxide which contributes to the high corrosion resistance observed. The cell assay result suggests that surfaces of this Pt-enhanced alloy endothelialize in a manner comparable to stainless steel.
authors.affiliation: National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland. obrienbh@gmail.com
authors.forename: Barry J
authors.initials: BJ
authors.lastname: O'Brien
authors.forename: Jon S
authors.initials: JS
authors.lastname: Stinson
authors.forename: Steve R
authors.initials: SR
authors.lastname: Larsen
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Eppihimer
authors.forename: William M
authors.initials: WM
authors.lastname: Carroll
mesh_terms: D000497:Alloys / Q000032:analysis / Q000737:chemistry*; D002319:Cardiovascular System; D049109:Cell Proliferation; D003343:Corrosion; D042783:Endothelial Cells / Q000166:cytology; D006801:Humans; D008422:Materials Testing; D010100:Oxygen / Q000032:analysis; D056951:Photoelectron Spectroscopy; D013232:Steel / Q000737:chemistry*; D015607:Stents; D013499:Surface Properties; D013696:Temperature; D013718:Tensile Strength
chemical_list: D000497:Alloys; D013232:Steel; D010100:Oxygen