title: Coupling reactions of hindered isonitriles and hindered alkyl thioacids: Mechanistic studies.
abstract: The coupling reaction between hindered thioacids and isonitriles is developed and described. The mechanism for the formation of the thiopyruvamide products is explored, and the method is applied to a selection of substrates.
authors.affiliation: Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Stockdill
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Wu
authors.forename: Samuel J
authors.initials: SJ
authors.lastname: Danishefsky