title: The use of muscle flaps in the salvage of infected exposed implants for internal fixation.
abstract: The treatment of infected exposed implants which have been used for internal fixation usually involves debridement and removal of the implant. This can result in an unstable fracture or spinal column. Muscle flaps may be used to salvage these implants since they provide soft-tissue cover and fresh vascularity. However, there have been few reports concerning their use and these have concentrated on the eradication of the infection and successful soft-tissue cover as the endpoint. There is no information on the factors which may influence the successful salvage of the implant using muscle flaps. We studied the results and factors affecting outcome in nine pedicled muscle flaps used in the treatment of exposed metal internal fixation with salvage of the implant as the primary endpoint. This was achieved in four cases. Factors predicting success were age < 30 years, the absence of comorbid conditions and a favourable microbiological profile. The growth of multiple organisms, a history of smoking and the presence of methicillin-resistant Staphylococcus aureus on wound cultures indicated a poor outcome. The use of antibiotic beads, vacuum-assisted closure and dressing, the surgical site, the type of flap performed and the time from primary surgery to flap cover were not predictive of outcome.
authors.affiliation: University Orthopaedics, Hand and Reconstructive Microsurgery Cluster, National University Hospital, Young Loo Lin School of Medicine, National University of Singapore, National University Health System, 5 Lower Kent Ridge Road, Singapore.
authors.forename: K-J
authors.initials: KJ
authors.lastname: Tan
authors.forename: C-T
authors.initials: CT
authors.lastname: Lim
authors.forename: A Y-T
authors.initials: AY
authors.lastname: Lim
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D006801:Humans; D016268:Internal Fixators; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation*; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000379:methods; D013524:Surgical Flaps; D013529:Surgical Wound Dehiscence / Q000601:surgery; D013530:Surgical Wound Infection / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult