[Study on the antibacterial activity of compounds from the isodon species].
We investigated antibacterial activities of ten compounds from Isodon species against five strains of Escherichia coli, Staphylococcus epidermidis, Serratia marcescens, Streptococcus mutans, and Helicobacter pylori. The compounds with the MIC values of 25 microg/ml were isodocarpin against Sta. epidermidis, Str. mutans, and H. pylori, nodosin against Sta. epidermidis and Str. mutans, oridonin against Ser. marcescens, and pedalitin against H. pylori.
Isobe
Takahiko
T
Department of Chemistry, Liberal Arts Center, Hyogo University of Health Sciences, Japan. isobe-t@huhs.ac.jp
Nagata
Kumiko
K
D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects*; D016480:Helicobacter pylori / Q000187:drug effects*; D037602:Isodon / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D012706:Serratia marcescens / Q000187:drug effects*; D013212:Staphylococcus epidermidis / Q000187:drug effects*; D013295:Streptococcus mutans / Q000187:drug effects*
D010936:Plant Extracts