title: Massive cranial osteolysis, skin changes, growth retardation and developmental delay: Gorham syndrome with systemic manifestations?
abstract: We report on a 16-month-old girl with multiple swellings on her skull due to massive osteolysis, growth retardation, facial anomalies, and wrinkly skin with mosaic hypopigmentation. She also had severe hypercalcemia, which gradually returned to normal levels. The condition likely represents Gorham syndrome with systemic manifestations.
authors.affiliation: Department of Pediatrics, Kasturba Medical College, Manipal, Karnataka, India. girishkatta@gmail.com
authors.forename: K M
authors.initials: KM
authors.lastname: Girisha
authors.forename: H K
authors.initials: HK
authors.lastname: Ganesh
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Rao
authors.forename: P S
authors.initials: PS
authors.lastname: Srilatha
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D002658:Developmental Disabilities / Q000235:genetics*; D005260:Female; D006130:Growth Disorders / Q000235:genetics*; D006801:Humans; D017496:Hypopigmentation / Q000235:genetics; D007223:Infant; D010015:Osteolysis, Essential / Q000235:genetics* / Q000473:pathology*; D012868:Skin Abnormalities / Q000235:genetics / Q000473:pathology; D012886:Skull / Q000473:pathology*; D013577:Syndrome