title: Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2).
abstract: Informatics for Integrating Biology and the Bedside (i2b2) is one of seven projects sponsored by the NIH Roadmap National Centers for Biomedical Computing (http://www.ncbcs.org). Its mission is to provide clinical investigators with the tools necessary to integrate medical record and clinical research data in the genomics age, a software suite to construct and integrate the modern clinical research chart. i2b2 software may be used by an enterprise's research community to find sets of interesting patients from electronic patient medical record data, while preserving patient privacy through a query tool interface. Project-specific mini-databases ("data marts") can be created from these sets to make highly detailed data available on these specific patients to the investigators on the i2b2 platform, as reviewed and restricted by the Institutional Review Board. The current version of this software has been released into the public domain and is available at the URL: http://www.i2b2.org/software.
authors.affiliation: Laboratory of Computer Science, Massachusetts General Hospital, Boston, Massachusetts 02129, USA. murphy.shawn@mgh.harvard.edu
authors.forename: Shawn N
authors.initials: SN
authors.lastname: Murphy
authors.forename: Griffin
authors.initials: G
authors.lastname: Weber
authors.forename: Michael
authors.initials: M
authors.lastname: Mendis
authors.forename: Vivian
authors.initials: V
authors.lastname: Gainer
authors.forename: Henry C
authors.initials: HC
authors.lastname: Chueh
authors.forename: Susanne
authors.initials: S
authors.lastname: Churchill
authors.forename: Isaac
authors.initials: I
authors.lastname: Kohane
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration* / Q000706:statistics & numerical data; D003628:Database Management Systems; D006801:Humans; D016247:Information Storage and Retrieval; D016347:Medical Records Systems, Computerized; D012984:Software; D018511:Systems Integration; D014481:United States; D014584:User-Computer Interface