title: Convergent evolution: pick your poison carefully.
abstract: Genomic and biochemical analyses reveal that two independently evolved serine protease venoms in mammals and lizards have converged on nearly identical protein structures. Likewise, in two groups of frog, an identical toxin, caerulein, has arisen repeatedly from unique genes in those lineages.
authors.affiliation: Mountain Lake Biological Station, Department of Biology, University of Virginia, Charlottesville, VA 22904, USA. bbrodie@virginia.edu
authors.forename: Edmund D
authors.initials: ED
authors.lastname: Brodie
mesh_terms: D000220:Adaptation, Biological / Q000235:genetics*; D000818:Animals; D001001:Anura / Q000235:genetics / Q000378:metabolism*; D019143:Evolution, Molecular; D008116:Lizards / Q000235:genetics / Q000378:metabolism*; D057057:Serine Proteases / Q000235:genetics*; D012788:Shrews / Q000378:metabolism*; D013045:Species Specificity; D014688:Venoms / Q000235:genetics*
chemical_list: D014688:Venoms; D057057:Serine Proteases