DNA (6-4) photolyases reduce Dewar isomers for isomerization into (6-4) lesions.
Repair of the Dewar valence isomers by (6-4) photolyases proceeds via an enzyme catalyzed ring-opening reaction of the Dewar lesion to the (6-4) photoproduct.
Glas
Andreas F
AF
Center for Integrative Protein Science, Department of Chemistry and Biochemistry, Ludwig-Maximilians University Munich, Butenandtstr. 5-13, 81377 Munich, Germany.
Kaya
Emine
E
Schneider
Sabine
S
Heil
Korbinian
K
Fazio
Danila
D
Maul
Melanie J
MJ
Carell
Thomas
T
D003596:Cytosine / Q000031:analogs & derivatives; D004249:DNA Damage; D004260:DNA Repair; D004277:DNA, Single-Stranded / Q000737:chemistry / Q000528:radiation effects; D004255:Deoxyribodipyrimidine Photo-Lyase / Q000737:chemistry*; D007536:Isomerism; D009841:Oligonucleotides / Q000737:chemistry*; D011740:Pyrimidine Dimers / Q000737:chemistry; D013936:Thymidine / Q000031:analogs & derivatives
D004277:DNA, Single-Stranded; D009841:Oligonucleotides; D011740:Pyrimidine Dimers; D003596:Cytosine; D004255:Deoxyribodipyrimidine Photo-Lyase; D013936:Thymidine