Conjugated polymer nanoparticles for biomedical in vivo imaging.
Conjugated polymer nanoparticles, produced by in situ colloidal Knoevenagel polymerization, show advantageous properties (bright emission, colloidal/chemical stability and mesoscopic size range) that allow the successful in vivo application to real-time sentinel lymph node mapping in a mouse model.
Kim
Sehoon
S
Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791, Korea. sehoonkim@kist.re.kr
Lim
Chang-Keun
CK
Na
Jinhee
J
Lee
Yong-Deok
YD
Kim
Kwangmeyung
K
Choi
Kuiwon
K
Leary
James F
JF
Kwon
Ick Chan
IC
D000818:Animals; D008198:Lymph Nodes / Q000166:cytology / Q000648:ultrastructure; D051379:Mice; D046529:Microscopy, Electron, Transmission; D057054:Molecular Imaging / Q000379:methods*; D015335:Molecular Probes / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D015335:Molecular Probes; D011108:Polymers; D014867:Water