title: Imaging resin-cast osteocyte lacuno-canalicular system at bone-bioactive glass interface by scanning electron microscopy.
abstract: The morphology of the osteocyte lacuno-canalicular system at the bone-biomaterial implant-interface has not been fully investigated. In this study, the resin-cast scanning electron microscopy technique was used, for the first time, to image the lacuno-canalicular network within neoformed bone around bioactive glass (BG) particles implanted in rat tibia bone marrow. The most salient finding was that the osteocyte canaliculi pass through the calcium-phosphorus layer formed at the bone-BG interface and reach the silica-rich layer of the reacted BG.
authors.affiliation: National Atomic Energy Commission, National Research Council, Salta, Argentina. agorustovich@gmail.com
authors.forename: Alejandro A
authors.initials: AA
authors.lastname: Gorustovich
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001853:Bone Marrow / Q000648:ultrastructure*; D001842:Bone and Bones / Q000648:ultrastructure*; D008297:Male; D008855:Microscopy, Electron, Scanning; D010011:Osteocytes / Q000648:ultrastructure*; D019736:Prostheses and Implants; D051381:Rats; D017208:Rats, Wistar; D013977:Tibia / Q000648:ultrastructure
chemical_list: D001672:Biocompatible Materials