title: Technical and clinical results after percutaneous angioplasty in nonmedial fibromuscular dysplasia: outcome after endovascular management of unifocal renal artery stenoses in 30 patients.
abstract: Although percutaneous transluminal renal angioplasty (PTRA) is associated with excellent results in medial fibromuscular dysplasia (FMD), the clinical and technical outcome in the less common nonmedial subtype of FMD is not clearly known. Angiographic PTRA results and clinical follow-up were documented, to report technical and clinical results in 30 patients with unifocal, nonmedial dysplastic stenoses. Balloon angioplasty was technically successful in only 65% of the lesions. Additional stenting, performed after PTRA failure in six patients, increased the initial technical success rate to 82%. Stenting was used in another lesion after restenosis, and long-term patency was achieved in only three of the seven stented lesions. Frequent restenoses and unusual complications were observed during follow-up. Stent fracture occurred in two cases. Overall, long-term clinical and technical successes were sustained in 70 and 76%, respectively. We conclude that nonmedial, unifocal renal artery dysplastic stenoses do not share the excellent prognosis of the medial type and that stenting should be avoided. Therefore, surgery should be considered in lesions remaining unresponsive to balloon dilatation, after a second PTRA attempt.
authors.affiliation: Service d'imagerie médicale, Hôpital de Rangueil, (Rangueil) Bâtiment H1, R.D.C, 1 avenue du Professeur Jean Poulhès, TSA 50032-31059, Toulouse Cedex 9, France. p.barrier@gmail.com
authors.forename: Pierre
authors.initials: P
authors.lastname: Barrier
authors.forename: Auriol
authors.initials: A
authors.lastname: Julien
authors.forename: Canevet
authors.initials: C
authors.lastname: Guillaume
authors.forename: Otal
authors.initials: O
authors.lastname: Philippe
authors.forename: Rousseau
authors.initials: R
authors.lastname: Hervé
authors.forename: Joffre
authors.initials: J
authors.lastname: Francis
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000792:Angiography / Q000379:methods; D017130:Angioplasty / Q000379:methods*; D000800:Angioplasty, Balloon / Q000295:instrumentation / Q000379:methods*; D015331:Cohort Studies; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D015607:Stents; D016896:Treatment Outcome; D014654:Vascular Patency / Q000502:physiology; D055815:Young Adult