Correlation study of pulmonary embolism and high-density lipoprotein cholesterol.
BACKGROUND
It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high-density lipoprotein cholesterol.


OBJECTIVE
Pulmonary embolism has a negative correlation with the level of high-density lipoprotein cholesterol.


METHODS
A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non-trunk embolism in group B.


RESULTS
The results showed that the level of high-density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non-trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high-density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C-reactive protein.


CONCLUSIONS
Pulmonary arterial trunk embolism is negatively correlated with the level of high-density lipoprotein cholesterol.
Wang
YuPeng
Y
Department of Heart Center, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China.
Wang
Ping
P
Li
HongWei
H
D000208:Acute Disease; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D016009:Chi-Square Distribution; D008076:Cholesterol, HDL / Q000097:blood*; D015536:Down-Regulation; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011655:Pulmonary Embolism / Q000097:blood* / Q000209:etiology; D012372:ROC Curve; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D015415:Biomarkers; D008076:Cholesterol, HDL; D014280:Triglycerides; D002097:C-Reactive Protein