Pneumocystis jirovecii Pneumonia.
Pneumocystis jirovecii has gained attention during the last decade in the context of the AIDS epidemic and the increasing use of cytotoxic and immunosuppressive therapies. This article summarizes current knowledge on biology, pathophysiology, epidemiology, diagnosis, prevention, and treatment of pulmonary P jirovecii infection, with a particular focus on the evolving pathophysiology and epidemiology. Pneumocystis pneumonia still remains a severe opportunistic infection, associated with a high mortality rate.
Catherinot
Emilie
E
Université Paris Descartes, Service de Maladies Infectieuses et Tropicales, 149 Rue de Sèvres, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker-Enfants Malades, Paris 75015, France.
Lanternier
Fanny
F
Bougnoux
Marie-Elisabeth
ME
Lecuit
Marc
M
Couderc
Louis-Jean
LJ
Lortholary
Olivier
O
D017088:AIDS-Related Opportunistic Infections; D006801:Humans; D016867:Immunocompromised Host; D045363:Pneumocystis carinii / Q000302:isolation & purification*; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*