title: Molecular imaging and therapy of cancer with radiolabeled nanoparticles.
abstract: This review summarizes the current state-of-the-art of radiolabeled nanoparticles for molecular imaging and internal radiotherapy applications targeting cancer. With the capacity to provide enormous flexibility, radiolabeled nanoparticles have the potential to profoundly impact disease diagnosis and patient management in the near future. Currently, the major challenges facing the research on radiolabeled nanoparticles are desirable (tumor) targeting efficacy, robust chemistry for both radionuclide encapsulation/incorporation and targeting ligand conjugation, favorable safety profile, as well as certain commercial and regulatory hurdles.
authors.affiliation: Department of Radiology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, Wisconsin, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Hong
authors.forename: Yin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jiangtao
authors.initials: J
authors.lastname: Sun
authors.forename: Weibo
authors.initials: W
authors.lastname: Cai