Nadroparine-induced skin necrosis on a patient with essential thrombocythaemia: a case report.
Skin necrosis is a rare but serious complication of subcutaneously administered low-molecular-weight heparin. We report a case of a 53-year-old female patient with skin necrosis induced by subcutaneous administration of nadroparine. The patient suffered from essential thrombocythaemia on a background of chronic myeloproliferative disease. She was admitted to our clinic with a subacute ileus due to endometriosis of the rectosigmoid junction. She underwent a high anterior resection and she received pre- and postoperative antithrombotic prophylaxis with subcutaneous nadroparine on a daily basis. On the 6th and 7th postoperative days, two skin necroses occurred at two injection sites.
Pramateftakis
Manousos-Georgios
MG
Department of Surgery, European Medical Center, Asklipiou 10, 57001 Thessaloniki, Greece. mpramateftakis@hotmail.com
Kanellos
Dimitrios
D
Psomas
Stefanos
S
Kanellos
Ioannis
I