ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing.
Chromatin interaction analysis with paired-end tag sequencing (ChIA-PET) is a new technology to study genome-wide long-range chromatin interactions bound by protein factors. Here we present ChIA-PET Tool, a software package for automatic processing of ChIA-PET sequence data, including linker filtering, mapping tags to reference genomes, identifying protein binding sites and chromatin interactions, and displaying the results on a graphical genome browser. ChIA-PET Tool is fast, accurate, comprehensive, user-friendly, and open source (available at http://chiapet.gis.a-star.edu.sg).
Li
Guoliang
G
Computational and Mathematical Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore, 138672, Republic of Singapore.
Fullwood
Melissa J
MJ
Xu
Han
H
Mulawadi
Fabianus Hendriyan
FH
Velkov
Stoyan
S
Vega
Vinsensius
V
Ariyaratne
Pramila Nuwantha
PN
Mohamed
Yusoff Bin
YB
Ooi
Hong-Sain
HS
Tennakoon
Chandana
C
Wei
Chia-Lin
CL
Ruan
Yijun
Y
Sung
Wing-Kin
WK
D001665:Binding Sites / Q000235:genetics; D002843:Chromatin / Q000737:chemistry / Q000378:metabolism*; D047369:Chromatin Immunoprecipitation; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D015894:Genome, Human; D006801:Humans; D011485:Protein Binding; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
D002843:Chromatin; D004268:DNA-Binding Proteins