Quantitative analysis of asymmetrical cortical activity based on power spectrum changes.
The present study intends to quantitatively analyze power changes in blood oxygenation level-dependent (BOLD) signals, and to investigate functional asymmetry of cortical activity in motor areas during sequential finger movements. A power spectrum method was employed, mainly in contrast with the signal magnitude analysis, to investigate functional asymmetry of motor area cortical activity. Six right-handed subjects were included in the functional magnetic resonance imaging (fMRI) experiments. Both bi-handed and single-handed movements were analyzed. The power spectrum method demonstrated that right-handed subjects exhibited a larger power difference in BOLD signals between task and rest states in the right motor area than in the left motor area. These results showed that more nerve cells were evoked in the right motor area of right-handed subjects. In addition, the power spectrum method was confirmed to be a valid quantitative-analysis method for brain asymmetry analyses.
Zhang
Jiang
J
School of Life Science and Technology, University of Electronic Science and Technology of China, 610054, Chengdu, China.
Chen
Huafu
H
Fang
Fang
F
Liao
Wei
W
D001931:Brain Mapping; D007839:Functional Laterality / Q000502:physiology*; D006225:Hand / Q000294:innervation / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D013058:Mass Spectrometry; D009044:Motor Cortex / Q000098:blood supply / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation / Q000379:methods
D010100:Oxygen