title: Evaluation of swallowing pressure in a patient with amyotrophic lateral sclerosis before and after cricopharyngeal myotomy using high-resolution manometry system.
abstract: BACKGROUND
  This study aimed to evaluate the pharyngeal pressure of a patient with, amyotrophic lateral sclerosis (ALS) before and after cricopharyngeal myotomy by high-resolution manometry (HRM) system.
  
  
  METHODS
  A 60-year-old man with ALS underwent cricopharyngeal myotomy for his intractable, aspiration. The swallowing pressure along the velopharynx and upper esophagus was measured using, the HRM 1 month before and 3 months after the surgery.
  
  
  RESULTS
  Before cricopharyngeal myotomy, the maximum values of the resting UES pressure, the dry swallowing, pressures in the velopharyngeal muscle zone and in the UES zone were 89, 95, and 171 mmHg, respectively. After surgery, the maximum values of both the resting pressure and dry swallowing, pressure in the UES zone remarkably decreased to 21 and 75 mmHg, respectively.
  
  
  CONCLUSIONS
  This is the first report showing the effect of cricopharyngeal myotomy by demonstrating, the difference in the swallowing pressure along the velopharynx and upper esophagus before and after, the surgery in an ALS patient using this HRM system.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. ktakasa@nagasaki-u.ac.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Takasaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Umeki
authors.forename: Kaori
authors.initials: K
authors.lastname: Enatsu
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Kumagami
authors.forename: Haruo
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology* / Q000601:surgery*; D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000503:physiopathology* / Q000601:surgery*; D005471:Fluoroscopy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods*; D008875:Middle Aged; D010609:Pharyngeal Muscles / Q000601:surgery*; D012815:Signal Processing, Computer-Assisted; D012984:Software; D014741:Video Recording