Approaches for novel enzyme discovery from marine environments.
The enormous pool of biodiversity in marine ecosystems is an excellent natural reservoir for acquiring an inventory of enzymes with potential for biotechnological applications. Moreover, the opportunity for sustainable resource management has been greatly enhanced by recent advances in culturing methods for recalcitrant microbes. In this review, we will focus primarily on successful examples in culturing marine microbes and provide an overview of work examining the biotechnological potential of the marine reservoir, mainly through genomic strategies, such as activity-based functional screening of genomic and metagenomic libraries and homology-driven screening of enormous amounts of sequence data.
Lee
Hyun Sook
HS
Korea Ocean Research and Development Institute, Ansan, PO Box 29, Seoul 425-600, South Korea.
Kwon
Kae Kyoung
KK
Kang
Sung Gyun
SG
Cha
Sun-Shin
SS
Kim
Sang-Jin
SJ
Lee
Jung-Hyun
JH
D044822:Biodiversity; D001709:Biotechnology / Q000379:methods*; D004798:Enzymes; D008386:Marine Biology / Q000379:methods*
D004798:Enzymes