title: Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors.
abstract: A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-beta (ERbeta).
authors.affiliation: Molekulare Zellphysiologie & Endokrinologie, Fachrichtung Biologie, Technische Universität Dresden, Dresden, Germany. Guenter.Vollmer@tu-dresden.de
authors.forename: Günter
authors.initials: G
authors.lastname: Vollmer
authors.forename: Anja
authors.initials: A
authors.lastname: Papke
authors.forename: Oliver
authors.initials: O
authors.lastname: Zierau