Steroids and alkaloids from the South China Sea sponge Axinella sp.
A new steroid 24beta-methylcholasta-1,8,14,22,25-penten-3-one-5alpha-ol (1) and a new alkaloid 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane (2), together with four known compounds, were isolated from the EtOH extract of the South China Sea sponge Axinella sp. The structures of 1 and 2 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data.
Qi
Shu-Hua
SH
Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou, China. shuhuaqi2001@yahoo.com
Wang
Yi-Fei
YF
Zhang
Si
S
D000818:Animals; D047089:Axinella / Q000737:chemistry*; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification*; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
C548692:1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane; D002783:Cholestenones; D026121:Indole Alkaloids; D013256:Steroids