title: Two novel furostanol saponins from Ophiopogon japonicus.
abstract: Two novel furostanol saponins were isolated from the fresh tubers of Ophiopogon japonicus. Comprehensive spectroscopic analysis allowed the chemical structures of the compounds to be assigned as (25R)-26-[(O-beta-d-glucopyranosyl-(1 --> 2)-beta-d-glucopyranosyl)]-22alpha-hydroxyfurost-5-ene-3-O-beta-d-xylopyranosyl-(1 --> 4)-O-[alpha-l-rhamnopyranosyl-(1 --> 2)]-beta-d-glucopyranoside (1, ophiopogonin F) and (25R)-26-[(O-beta-d-glucopyranosyl-(1 --> 6)-beta-d-glucopyranosyl)]-22alpha-hydroxyfurost-5-ene-3-O-beta-d-xylopyranosyl-(1 --> 4)-O-[alpha-l-rhamnopyranosyl-(1 --> 2)]-beta-d-glucopyranoside (2, ophiopogonin G). The rare furostanol saponins with two glucosyl residues at C-26 position were isolated from the natural source for the first time.
authors.affiliation: Beijing Institute of Radiation Medicine, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Zou
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Kang
authors.forename: He-Shui
authors.initials: HS
authors.lastname: Yu
authors.forename: Yi-Xun
authors.initials: YX
authors.lastname: Liu
authors.forename: Xin-Bo
authors.initials: XB
authors.lastname: Song
authors.forename: Bai-Ping
authors.initials: BP
authors.lastname: Ma
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031441:Ophiopogon / Q000737:chemistry*; D035281:Plant Tubers / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D004365:Drugs, Chinese Herbal; D012503:Saponins; D013150:Spirostans; C548597:ophiopogonin F; C548598:ophiopogonin G