title: [Clinical case of acute renal failure revealing an autoimmune hypothyroidism].
abstract: Although the clinic picture is often indicative of muscle manifestations in patients with hypothyroidism, signs and symptoms of this condition are variable from simple elevation of serum muscle enzymes with myalgia, muscle weakness, cramps to rhabdomyolysis with acute renal failure which remains a rare event. Thyroid hormones affect the function of almost every body organ, and thyroid dysfunction produces a wide range of metabolic disturbances. Hypothyroidism is associated with significant effects on the kidney which the pathophysiology seems to be multifactorial, but the exact mechanisms remain poorly understood. Hypothyroidism as a cause of renal impairment is usually overlooked, leading to unnecessary diagnostic procedures. The main objective of our observation is to report a case of acute renal failure revealing an autoimmune hypothyroidism in which thyroid hormone substitution led to a significant improvement in muscular, thyroid and renal disorders.
authors.affiliation: Service de néphrologie-dialyse et de transplantation rénale, hôpital militaire d'instruction Mohammed V, faculté de médecine et de pharmacie, Hay Riad, CP 10000 Rabat, Maroc. dinamontasser@live.fr
authors.forename: Dina Ibrahim
authors.initials: DI
authors.lastname: Montasser
authors.forename: Mohamed
authors.initials: M
authors.lastname: Hassani
authors.forename: Yassir
authors.initials: Y
authors.lastname: Zajjari
authors.forename: Abdelali
authors.initials: A
authors.lastname: Bahadi
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alayoud
authors.forename: Amine
authors.initials: A
authors.lastname: Hamzi
authors.forename: Kawtar
authors.initials: K
authors.lastname: Hassani
authors.forename: Omar
authors.initials: O
authors.lastname: Moujoud
authors.forename: Mohamed
authors.initials: M
authors.lastname: Asseraji
authors.forename: Moncif
authors.initials: M
authors.lastname: Kadiri
authors.forename: Taoufik
authors.initials: T
authors.lastname: Aatif
authors.forename: Driss
authors.initials: D
authors.lastname: El Kabbaj
authors.forename: Mohamed
authors.initials: M
authors.lastname: Benyahia
authors.forename: Mustapha
authors.initials: M
authors.lastname: Allam
authors.forename: Ismail
authors.initials: I
authors.lastname: Akhmouch
authors.forename: Zouhir
authors.initials: Z
authors.lastname: Oualim
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000368:Aged; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D013963:Thyroid Hormones / Q000627:therapeutic use; D013967:Thyroiditis, Autoimmune / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D013963:Thyroid Hormones