Effects of immunotoxic activity of the major essential oil of Angelica purpuraefolia Chung against Aedes aegypti L.
The rhizomes parts of Angelica purpuraefolia were extracted and the major essential oils composition and immunotoxic effects were studied. The analyses were conducted by gas chromatography and mass spectroscopy (GC-MS) revealed that the essential oils of A. purpuraefolia. The A. purpuraefolia essential oil (APEO) yield was 0.37%, and GC/MS analysis revealed that its major constituents were β-Phellandrene (32.11%), Nerolidol (10.11%), Pyrimidine derivative (27.33%), Heptadecane (4.33%), and Celorbicol (6.33%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC(50) value of 31.21 ppm and an LC(90) value of 87.22 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxic agents against A. aegypti.
Park
Yool-Jin
YJ
Division of Environmental and Resource, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan, South Korea.
Chung
Ill-Min
IM
Moon
Hyung-In
HI
D000330:Aedes / Q000187:drug effects*; D000473:Alkanes / Q000032:analysis; D029969:Angelica / Q000737:chemistry*; D000818:Animals; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000032:analysis / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011743:Pyrimidines / Q000032:analysis; D027343:Rhizome / Q000737:chemistry; D012717:Sesquiterpenes / Q000032:analysis
D000473:Alkanes; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D011743:Pyrimidines; D012717:Sesquiterpenes; C058582:beta-phellandrene; C016486:heptadecane; C037055:nerolidol