title: [The value of "migraine surgery". Overview of the pathophysiological concept and current evidence].
abstract: Often without sufficient scientific evidence, unconventional methods for migraine treatment are being put forward. Recently a trial using "migraine surgery" has been published. Its design is based on a concept of migraine pathogenesis without any scientific background and includes several severe methodological flaws. In spite of the above, the study is frequently cited in the lay press. The surgical procedure as well as the study are critically discussed.
authors.affiliation: Westdeutsches Kopfschmerzzentrum, Neurologische Klinik, Universitätsklinikum Essen, 45147 Essen. Charly.Gaul@gmx.de
authors.forename: C
authors.initials: C
authors.lastname: Gaul
authors.forename: D
authors.initials: D
authors.lastname: Holle
authors.forename: P S
authors.initials: PS
authors.lastname: Sandor
authors.forename: S
authors.initials: S
authors.lastname: Evers
authors.forename: G
authors.initials: G
authors.lastname: Broessner
authors.forename: A
authors.initials: A
authors.lastname: Straube
authors.forename: H-C
authors.initials: HC
authors.lastname: Diener
mesh_terms: D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D003131:Combined Modality Therapy; D019317:Evidence-Based Medicine; D005152:Facial Muscles / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005546:Forehead / Q000601:surgery*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology* / Q000601:surgery*; D009209:Myofascial Pain Syndromes / Q000503:physiopathology / Q000601:surgery; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D055502:Secondary Prevention; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000503:physiopathology / Q000601:surgery
chemical_list: D019274:Botulinum Toxins, Type A