A new triterpenoid saponin from the stem of Akebia trifoliata var. australis.
A new triterpene glycoside mutongsaponin F (1), together with five known saponins and two known lipids, was isolated from the 70% ethanol extract of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd. Their structures were elucidated on the basis of the spectroscopic analysis and physicochemical properties as 3-beta-[(beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)-O-]-alpha-L-arabinopyranosyl)oxy]-30-norolean-12-en-28-oic acid alpha-L-rhamnopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-glucopyranosyl ester (1), 3-beta-[(beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)-O-]-alpha-L-arabinopyranosyl)oxy]-30-norolean-12-en-28-oic acid (2), leonticin E (3), collinsonidin (4), arjunolic acid 28-O-glucopyranoside (5), asiatic acid 28-O-glucopyranoside (6), soya-cerebroside I (7), and 1-O-alpha-L-galactosyl-(1-->6)-O-beta-D-galactosyl-3-O-hexadecanoyl-glycerol (8), respectively.
Gao
Hui-Min
HM
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Wang
Zhi-Min
ZM
Wang
Wei-Hao
WH
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D029626:Ranunculaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D004365:Drugs, Chinese Herbal; D012503:Saponins; D014315:Triterpenes; C548610:mutongsaponin F