Radiation dose-volume effects in the esophagus.
Publications relating esophageal radiation toxicity to clinical variables and to quantitative dose and dose-volume measures derived from three-dimensional conformal radiotherapy for non-small-cell lung cancer are reviewed. A variety of clinical and dosimetric parameters have been associated with acute and late toxicity. Suggestions for future studies are presented.
Werner-Wasik
Maria
M
Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA 19107-5097, USA. maria.werner-wasik@jeffersonhospital.org
Yorke
Ellen
E
Deasy
Joseph
J
Nam
Jiho
J
Marks
Lawrence B
LB
D000208:Acute Disease; D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D004941:Esophagitis / Q000209:etiology* / Q000473:pathology; D004947:Esophagus / Q000000981:diagnostic imaging / Q000502:physiology / Q000528:radiation effects*; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008954:Models, Biological; D011832:Radiation Injuries / Q000150:complications*; D011859:Radiography; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D012306:Risk