title: Two new sesquiterpene glucosides from the leaves of Nicotiana tabacum.
abstract: Two new sesquiterpene glycosides, 11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside (1) and rishitin M1-13-O-beta-D-glucopyranoside (2), have been isolated from the leaves of Nicotiana tabacum. Their structures were established by spectroscopic methods including (1)H, (13)C, and 2D NMR. The absolute configuration of the side chain in compound 1 was determined as R by NOESY and NOE difference spectra.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Feng
authors.forename: Jun-Song
authors.initials: JS
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Luo
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D014026:Nicotiana / Q000737:chemistry*
chemical_list: C548422:11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D012717:Sesquiterpenes; C548423:rishitin M1-13-O-beta-D-glucopyranoside