title: New phthalates from Phyllanthus muellerianus (Euphorbiaceae).
abstract: Species of the genus Phyllanthus are known for their medicinal values and many are explored phytochemically. Some of them produce phthalates which usually have antimicrobial properties. This paper deals with the phytochemical investigation on Phyllanthus muellerianus. As a result, five compounds, bis(2-ethyloctyl)phthalate (1), bis(2-ethylicosyl)phthalate (2), 3-friedelanone (3), beta-sitosterol (4), and methyl gallate (5), have been isolated and characterized. Metabolites 1 and 2 are new compounds, while 3-5 have been isolated for the first time from this source. Structures of all the isolates were established on the basis of MS, 1D and 2D NMR spectral data and in comparison with the reported data.
authors.affiliation: Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan. drsaleem_kr@yahoo.com
authors.forename: Muhammad
authors.initials: M
authors.lastname: Saleem
authors.forename: Mamona
authors.initials: M
authors.lastname: Nazir
authors.forename: Naseem
authors.initials: N
authors.lastname: Akhtar
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Onocha
authors.forename: Naheed
authors.initials: N
authors.lastname: Riaz
authors.forename: Abdul
authors.initials: A
authors.lastname: Jabbar
authors.forename: Muhammad
authors.initials: M
authors.lastname: Shaiq Ali
authors.forename: Nighat
authors.initials: N
authors.lastname: Sultana
mesh_terms: D005707:Gallic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D009549:Nigeria; D019906:Nuclear Magnetic Resonance, Biomolecular; D010795:Phthalic Acids / Q000737:chemistry / Q000302:isolation & purification*; D029803:Phyllanthus / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D010795:Phthalic Acids; D012855:Sitosterols; D014315:Triterpenes; D005707:Gallic Acid