title: [Application of continuous controlled administration of three agents for total intravenous anesthesia].
abstract: General anesthesia was maintained by continuous administration of propofol, rocuronium and remifentanil. The dose of the medicine was determined by the effect site concentration calculated on a pharmacokinetics simulator respectively. Furthermore, a pharmacokinetics simulator enabled us to predict duration before the appearance of awareness.
authors.affiliation: Department of Anesthesia, Shakaihoken Kobe Central Hospital, Kobe 651-1145.
authors.forename: Noriko
authors.initials: N
authors.lastname: Hiramatsu
authors.forename: Shinichirou
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Kohei
authors.initials: K
authors.lastname: Kimura
authors.forename: Takashi
authors.initials: T
authors.lastname: Hirata
mesh_terms: D000328:Adult; D000732:Androstanols / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D000768:Anesthesia, General; D003198:Computer Simulation; D006801:Humans; D010880:Piperidines / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D015742:Propofol / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D000077208:Remifentanil; D000077123:Rocuronium; D012984:Software
chemical_list: D000732:Androstanols; D010880:Piperidines; D000077208:Remifentanil; D000077123:Rocuronium; D015742:Propofol