Two new sesquiterpene glucosides from the leaves of Nicotiana tabacum.
Two new sesquiterpene glycosides, 11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside (1) and rishitin M1-13-O-beta-D-glucopyranoside (2), have been isolated from the leaves of Nicotiana tabacum. Their structures were established by spectroscopic methods including (1)H, (13)C, and 2D NMR. The absolute configuration of the side chain in compound 1 was determined as R by NOESY and NOE difference spectra.
Feng
Xin
X
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Wang
Jun-Song
JS
Luo
Jun
J
Kong
Ling-Yi
LY
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D014026:Nicotiana / Q000737:chemistry*
C548422:11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D012717:Sesquiterpenes; C548423:rishitin M1-13-O-beta-D-glucopyranoside