Selectively nonselective kinase inhibition: striking the right balance.
Morphy
Richard
R
Medicinal Chemistry Department, Schering-Plough, Newhouse, Lanarkshire, ML1 5SH, UK. richard.morphy@spcorp.com
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D015195:Drug Design; D055808:Drug Discovery; D006801:Humans; D011485:Protein Binding; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors