title: Development of a deformable lung phantom for the evaluation of deformable registration.
abstract: The deformable lung phantom was developed to account for the patient breathing motion, and to evaluate for a deformable image registration algorithm. The phantom consisted of an acryl cylinder filled with water and a latex balloon located in the inner space of the cylinder. A silicon membrane was attached to the inferior end of the phantom. This silicon membrane was designed to simulate a real lung diaphragm and to reduce motor workload. This specific design was able to reduce the metal use which may prevent infrared sensing of the real position management (RPM) gating system on 4D CT image acquisition. Verification of intensity based 3D demon deformable registration was based on peak exhale and peak inhale breathing phases. The registration differences ranged from 0.85 mm to 1.47 mm, and accuracy was determined according to inner target deformation. This phantom was able to simulate the features and deformation of real human lung and has the potential for wide application in 4D radiation treatment planning.
authors.affiliation: Dept. of Biomedical Engineering, College of Medicine, Catholic University, Seoul, Korea.
authors.forename: Jina
authors.initials: J
authors.lastname: Chang
authors.forename: Tae-Suk
authors.initials: TS
authors.lastname: Suh
authors.forename: Dong-Soo
authors.initials: DS
authors.lastname: Lee
mesh_terms: D000179:Acrylates / Q000737:chemistry; D000465:Algorithms; D016477:Artifacts; D056973:Four-Dimensional Computed Tomography / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D007840:Latex / Q000737:chemistry; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D019047:Phantoms, Imaging; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results; D015656:Respiratory Mechanics; D012680:Sensitivity and Specificity; D012825:Silicon / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D000179:Acrylates; D007840:Latex; D014867:Water; D012825:Silicon