title: A highly selective fluorescent probe for Hg(2+) based on a rhodamine-coumarin conjugate.
abstract: A fluorescent probe 1 for Hg(2+) based on a rhodamine-coumarin conjugate was designed and synthesized. Probe 1 exhibits high sensitivity and selectivity for sensing Hg(2+), and about a 24-fold increase in fluorescence emission intensity is observed upon binding excess Hg(2+) in 50% water/ethanol buffered at pH 7.24. The fluorescence response to Hg(2+) is attributed to the 1:1 complex formation between probe 1 and Hg(2+), which has been utilized as the basis for the selective detection of Hg(2+). Besides, probe 1 was also found to show a reversible dual chromo- and fluorogenic response toward Hg(2+) likely due to the chelation-induced ring opening of rhodamine spirolactam. The analytical performance characteristics of the proposed Hg(2+)-sensitive probe were investigated. The linear response range covers a concentration range of Hg(2+) from 8.0x10(-8) to 1.0x10(-5)molL(-1) and the detection limit is 4.0x10(-8)molL(-1). The determination of Hg(2+) in both tap and river water samples displays satisfactory results.
authors.affiliation: College of Pharmacology, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, PR China.
authors.forename: Qiu-Juan
authors.initials: QJ
authors.lastname: Ma
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Zhang
authors.forename: Xu-Hua
authors.initials: XH
authors.lastname: Zhao
authors.forename: Zhen
authors.initials: Z
authors.lastname: Jin
authors.forename: Guo-Jiang
authors.initials: GJ
authors.lastname: Mao
authors.forename: Guo-Li
authors.initials: GL
authors.lastname: Shen
authors.forename: Ru-Qin
authors.initials: RQ
authors.lastname: Yu
mesh_terms: D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D012235:Rhodamines; D014874:Water Pollutants, Chemical; C030123:coumarin; D008628:Mercury