title: Metastatic malignant melanoma within meningioma with intratumoral infarct: report of an unusual case and literature review.
abstract: We report an unusual case of a patient with a sphenoid wing meningioma that after a few years of static radiological appearance presented with sudden deterioration following rapid growth of tumor with intratumoral infarct. The patient underwent surgery and malignant melanoma deposits within the meningioma were demonstrated on histopathological examination. She had a history of a malignant melanoma (MM) excised from the left forearm 10 months ago with no evidence of recurrence. Although metastasis to meningioma has been widely reported, this is only the second report where the primary tumor is MM. In addition, to the best of our knowledge, intratumoral hypodensity from metastasis is unusual. The tumor-to-tumor phenomenon is discussed and the literature is reviewed.
authors.affiliation: Department of Neurosurgery, Leeds General Infirmary, United Kingdom. debasishpal@yahoo.co.uk
authors.forename: D
authors.initials: D
authors.lastname: Pal
authors.forename: D
authors.initials: D
authors.lastname: Bhargava
authors.forename: S D
authors.initials: SD
authors.lastname: Bucur
authors.forename: A
authors.initials: A
authors.lastname: Shivane
authors.forename: A
authors.initials: A
authors.lastname: Chakrabarty
authors.forename: P
authors.initials: P
authors.lastname: Van Hille
mesh_terms: D005260:Female; D006801:Humans; D008545:Melanoma / Q000556:secondary* / Q000601:surgery; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008579:Meningioma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed