Benign myoepithelioma of the lung - a case report and review of the literature.
BACKGROUND
Benign myoepithelioma is extremely rare in the lung, to the best of our knowledge; only five cases have been reported in the literature.


METHODS
An 18-years woman complained from tiredness and fever during four months. Laboratory findings and fibroscopies were normal. CT of the thorax demonstrated a nodule in the left segment of the Fowler. Left inferior lobectomy was performed comporting a firm nodule of 25 mm, lifting the bronchial mucous membrane. Histologically, there was a proliferation of small cells of a plasmocytoid-type, with a predominantly whorled pattern. No mitotic activity or necrosis was seen in the tumor. Immuhistochemically, the tumor cells positive for smooth muscle actin, vimentine, and S100 protein. They were negatives for cytokeratine, chromogranine and HMB45. The diagnosis of benign myoepithelioma of the lung is so confirmed. The patient recovered well at 6 months follow-up.


CONCLUSIONS
Benign myoepithelioma is a rare pulmonary neoplasm distinct from pleomorphic adenoma, which should be considered in the differential diagnosis of lung nodules.
Kourda
Jihene
J
Department of Pathology, Abderrahman Mami Hospital, Ariana, Tunisia. jihenekourda@yahoo.fr.
Ismail
Olfa
O
Smati
Bel Hssan
BH
Ayadi
Aida
A
Kilani
Tarek
T
El Mezni
Faouzi
F