title: Successful closure of left-to-right patent ductus arteriosus in three dogs with concurrent pulmonary hypertension.
abstract: Closure of reversed patent ductus arteriosus (PDA) is generally accepted to be contraindicated due to case based evidence of worsened outcomes, but little is known about closure of left-to-right PDA with concurrent pulmonary hypertension (PH). This report describes three dogs presenting with varying severity of PH and clinical signs, all with documented left-to-right PDA. The PDA was closed in each case; either by surgical ligation or transarterial device occlusion, and follow up was available for a minimum of 8 months. Every case had a successful outcome with improvement or resolution of PH and associated clinical signs.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610-0126, USA.
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Seibert
authors.forename: Herbert W
authors.initials: HW
authors.lastname: Maisenbacher
authors.forename: Robert
authors.initials: R
authors.lastname: Prosek
authors.forename: Darcy B
authors.initials: DB
authors.lastname: Adin
authors.forename: Wendy G
authors.initials: WG
authors.lastname: Arsenault
authors.forename: Amara H
authors.initials: AH
authors.lastname: Estrada
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000601:surgery / Q000662:veterinary*; D004452:Echocardiography / Q000662:veterinary; D005260:Female; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000601:surgery / Q000662:veterinary*; D008297:Male; D016896:Treatment Outcome