title: The assessment of the filtering bleb function with anterior segment optical coherence tomography.
abstract: OBJECTIVE
  To assess the usefulness of anterior segment optical coherence tomography (AS-OCT) in evaluating postoperative filtering bleb function.
  
  
  METHODS
  Forty-eight eyes of 39 patients who had earlier undergone trabeculectomy were enrolled. Blebs were imaged with a commercially available AS-OCT system. The correlation between intraocular pressure (IOP) and 4 quantitative parameters, bleb height, bleb wall thickness, and the height and extent of internal cavity, and 2 qualitative parameters, bleb wall reflectivity, and the presence or absence of posterior episcleral fluid, were analyzed.
  
  
  RESULTS
  Of the 39 participants, 25 (64.1%) were males (mean age, 65.3±10.0 y). The height and extent of the internal cavity and the bleb height were not correlated with the IOP. The bleb wall thickness was negatively (P=0.004) correlated with the IOP. The mean IOP in eyes with a low-reflectivity bleb wall was significantly (P=0.001) lower than in eyes with a high-reflectivity wall. The IOP levels were significantly (P=0.008) lower in eyes with posterior episcleral fluid than in eyes without it.
  
  
  CONCLUSIONS
  AS-OCT is a useful tool to evaluate filtering bleb function. The height and extent of the total bleb and the internal cavity were not correlated with IOP control. A low-reflectivity wall and the presence of episcleral fluid were associated with lower IOP.
authors.affiliation: Department of Ophthalmology, Osaka University Medical School, Suita, 565-0871, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Tominaga
authors.forename: Atsuya
authors.initials: A
authors.lastname: Miki
authors.forename: Yuko
authors.initials: Y
authors.lastname: Yamazaki
authors.forename: Kenji
authors.initials: K
authors.lastname: Matsushita
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Otori
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment / Q000503:physiopathology*; D001768:Blister / Q000503:physiopathology*; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D011184:Postoperative Period; D013524:Surgical Flaps; D041623:Tomography, Optical Coherence; D014130:Trabeculectomy