Four-coordinate As(III)-N,S complexes: synthesis, structure, properties, and biological relevance.
Air-stable four-coordinate As(III) complexes, [As(L4)Cl] (1) and [As(L4)I] (2), were prepared using a rearranged form of the deprotonated benzothiazoline ligand, 2-(pyridin-2-yl)-2,3-dihydrobenzo[d]thiazole. Complexes 1 and 2 have been characterized by FTIR, (1)H NMR, UV-vis, and elemental microanalysis. The solid-state structure of 2 was also solved. The unusual and rare four-coordinate geometry of 2 elucidates possible binding modes and properties of N,S-ligated As(III) that may be encountered in biology.
Ezeh
Vivian C
VC
Department of Chemistry, The University of Georgia, 1001 Cedar Street, Athens, Georgia 30602, USA.
Patra
Ashis K
AK
Harrop
Todd C
TC
D001152:Arsenicals / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008958:Models, Molecular; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods; D013455:Sulfur / Q000737:chemistry*
D001152:Arsenicals; D013455:Sulfur; D009584:Nitrogen