Chronic pain: pathophysiology and treatment implications.
An examination of the current understanding of the processes and related therapies aimed at treatment of chronic pain in animals is presented. Discussion focuses on mechanisms involved in the neural pathways of chronic pain, differences between acute and chronic pain, and pharmacologic options for chronic pain as they relate to inflammatory, neoplastic, and neuropathic processes.
Greene
Stephen A
SA
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610, USA. sag@vetmed.wsu.edu
D000700:Analgesics / Q000627:therapeutic use; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002415:Cats; D002908:Chronic Disease; D004285:Dogs; D009369:Neoplasms / Q000150:complications / Q000662:veterinary; D009422:Nervous System Diseases / Q000150:complications / Q000662:veterinary; D009424:Nervous System Physiological Phenomena; D009434:Neural Pathways / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*; D020671:Posterior Horn Cells / Q000503:physiopathology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D016194:Receptors, N-Methyl-D-Aspartate