Pregnane glycoside from Hemidesmus indicus as a potential anti-oxidant and anti-dyslipidemic agent.
A new pregnane glycoside hindicusine (1) was isolated from the CHCl(3)-EtOH (3 : 2) extract of Hemidesmus indicus, whose structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (5) were evaluated for their anti-oxidant and anti-dyslipidemic activities.
Sethi
Arun
A
Department of Chemistry, University of Lucknow, Lucknow, India. alkaarunsethi@rediffmail.com
Bhatia
Akriti
A
Srivastava
Sanjay
S
Bhatia
Geetika
G
Khan
M M
MM
Khanna
A K
AK
Saxena
J K
JK
D000818:Animals; D000975:Antioxidants / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D031102:Hemidesmus / Q000737:chemistry*; D006949:Hyperlipidemias / Q000139:chemically induced / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000737:chemistry* / Q000627:therapeutic use*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011092:Polyethylene Glycols / Q000633:toxicity; D011278:Pregnanes / Q000737:chemistry*; D051381:Rats
D000975:Antioxidants; D006027:Glycosides; D000960:Hypolipidemic Agents; D011278:Pregnanes; D011092:Polyethylene Glycols; C016811:tyloxapol