title: In response to "a gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system".
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Raybon
authors.forename: Charles F
authors.initials: CF
authors.lastname: Albright
mesh_terms: D000409:Alanine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors*; D016229:Amyloid beta-Peptides / Q000134:cerebrospinal fluid* / Q000378:metabolism; D019540:Area Under Curve; D001381:Azepines / Q000008:administration & dosage / Q000494:pharmacology*; D035843:Biomedical Research / Q000379:methods*; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D013997:Time Factors
chemical_list: D016229:Amyloid beta-Peptides; D001381:Azepines; D004791:Enzyme Inhibitors; C484278:N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide; D053829:Amyloid Precursor Protein Secretases; D000409:Alanine