title: An automatic computer-aided detection scheme for pneumoconiosis on digital chest radiographs.
abstract: This paper presents an automatic computer-aided detection scheme on digital chest radiographs to detect pneumoconiosis. Firstly, the lung fields are segmented from a digital chest X-ray image by using the active shape model method. Then, the lung fields are subdivided into six non-overlapping regions, according to Chinese diagnosis criteria of pneumoconiosis. The multi-scale difference filter bank is applied to the chest image to enhance the details of the small opacities, and the texture features are calculated from each region of the original and the processed images, respectively. After extracting the most relevant ones from the feature sets, support vector machine classifiers are utilized to separate the samples into the normal and the abnormal sets. Finally, the final classification is performed by the chest-based report-out and the classification probability values of six regions. Experiments are conducted on randomly selected images from our chest database. Both the training and the testing sets have 300 normal and 125 pneumoconiosis cases. In the training phase, training models and weighting factors for each region are derived. We evaluate the scheme using the full feature vectors or the selected feature vectors of the testing set. The results show that the classification performances are high. Compared with the previous methods, our fully automated scheme has a higher accuracy and a more convenient interaction. The scheme is very helpful to mass screening of pneumoconiosis in clinic.
authors.affiliation: Department of Biomedical Engineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai, China.
authors.forename: Peichun
authors.initials: P
authors.lastname: Yu
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhu
authors.forename: Chao
authors.initials: C
authors.lastname: Yang
authors.forename: Xiwen
authors.initials: X
authors.lastname: Sun
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008875:Middle Aged; D010363:Pattern Recognition, Automated / Q000379:methods*; D011009:Pneumoconiosis / Q000000981:diagnostic imaging*; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult