title: A multicenter investigation of OPTI-FREE RepleniSH multi-purpose disinfecting solution impact on soft contact lens patient comfort.
abstract: OBJECTIVE
  Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE((R)) RepleniSH((R)) Multi-Purpose Disinfecting Solution (MPDS).
  
  
  METHODS
  This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE((R)) Multi-Purpose Solution (MPS) Easy Rub((R)) or ReNu MultiPlus((R)) MPS. The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit.
  
  
  RESULTS
  The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).
  
  
  CONCLUSIONS
  The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE((R)) MPS Easy Rub((R)) or ReNu MultiPlus((R)) MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.
authors.affiliation: Wyomissing Optometric Center, Wyomissing, PA, USA. drcorbin@wyoopto.com
authors.forename: Glenn S
authors.initials: GS
authors.lastname: Corbin
authors.forename: Linda
authors.initials: L
authors.lastname: Bennett
authors.forename: Louis
authors.initials: L
authors.lastname: Espejo
authors.forename: Suzanne
authors.initials: S
authors.lastname: Carducci
authors.forename: Andrew
authors.initials: A
authors.lastname: Sacco
authors.forename: Robert
authors.initials: R
authors.lastname: Hannigan
authors.forename: Stuart
authors.initials: S
authors.lastname: Schatz