Atypical mycobacterium keratitis associated with penetrating keratoplasty: case report of successful therapy with topical gatifloxacin 0.3%.
OBJECTIVE
To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.


METHODS
A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.


RESULTS
Clinical examination of the patient revealed an infiltrate at the inferior graft-host junction with a satellite lesion with a mild inflammatory reaction in the anterior chamber. Microbiologic evaluation confirmed the diagnosis of atypical mycobacteria keratitis. The corneal abscess was completely eradicated with a topical course of gatifloxacin 0.3% with preservation of graft clarity and good visual acuity. Topical treatment with gatifloxacin 0.3% was continued for an additional period of 5 months.


CONCLUSIONS
Topical gatifloxacin 0.3% may be successfully used to treat microbial keratitis resulting from atypical mycobacteria.
Perez-Balbuena
Ana Lilia
AL
Cornea & Refractive Service, Asociación para Evitar la Ceguera en México, Hospital Dr. Luis Sánchez Bulnes, Vicente Garcia Torres, 46 San Lucas Coyoacan, Mexico City, Mexico. albalbuena@prodigy.net.mx
Vanzzini-Zago
Virginia
V
Garza
Manuel
M
Cancino
Diego Cuevas
DC
D000287:Administration, Topical; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D024841:Fluoroquinolones / Q000627:therapeutic use*; D000077734:Gatifloxacin; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D016926:Mycobacterium chelonae
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D000077734:Gatifloxacin