The dynamics of transmission and spatial distribution of malaria in riverside areas of Porto Velho, Rondônia, in the Amazon region of Brazil.
The study area in Rondônia was the site of extensive malaria epidemic outbreaks in the 19(th) and 20(th) centuries related to environmental impacts, with large immigration flows. The present work analyzes the transmission dynamics of malaria in these areas to propose measures for avoiding epidemic outbreaks due to the construction of two Hydroelectric Power Plants. A population based baseline demographic census and a malaria prevalence follow up were performed in two river side localities in the suburbs of Porto Velho city and in its rural vicinity. The quantification and nature of malaria parasites in clinical patients and asymptomatic parasite carriers were performed using microscopic and Real Time PCR methodologies. Anopheles densities and their seasonal variation were done by monthly captures for defining HBR (hourly biting rate) values.


RESULTS
(i) malaria among residents show the riverside profile, with population at risk represented by children and young adults; (ii) asymptomatic vivax and falciparum malaria parasite carriers correspond to around 15% of adults living in the area; (iii) vivax malaria relapses were responsible for 30% of clinical cases; (iv) malaria risk for the residents was evaluated as 20-25% for vivax and 5-7% for falciparum malaria; (v) anopheline densities shown outdoors HBR values 5 to 10 fold higher than indoors and reach 10.000 bites/person/year; (vi) very high incidence observed in one of the surveyed localities was explained by a micro epidemic outbreak affecting visitors and temporary residents. Temporary residents living in tents or shacks are accessible to outdoors transmission. Seasonal fishermen were the main group at risk in the study and were responsible for a 2.6 fold increase in the malaria incidence in the locality. This situation illustrates the danger of extensive epidemic outbreaks when thousands of workers and secondary immigrant population will arrive attracted by opportunities opened by the Hydroelectric Power Plants constructions.
Katsuragawa
Tony Hiroshi
TH
Laboratory of Epidemiology, Instituto de Pesquisas em Patologias Tropicais, Porto Velho, Rondonia, Brazil.
Gil
Luiz Herman Soares
LH
Tada
Mauro Shugiro
MS
de Almeida e Silva
Alexandre
A
Costa
Joana D'Arc Neves
JD
Araújo
Maisa da Silva
Mda S
Escobar
Ana Lúcia
AL
da Silva
Luiz Hildebrando Pereira
LH
D000818:Animals; D000852:Anopheles / Q000254:growth & development* / Q000469:parasitology; D001938:Brazil / Q000453:epidemiology; D005843:Geography; D006801:Humans; D015994:Incidence; D007303:Insect Vectors / Q000254:growth & development / Q000469:parasitology; D016778:Malaria, Falciparum / Q000453:epidemiology / Q000635:transmission*; D016780:Malaria, Vivax / Q000453:epidemiology / Q000635:transmission*; D010963:Plasmodium falciparum / Q000235:genetics / Q000302:isolation & purification; D010966:Plasmodium vivax / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D011157:Population Dynamics; D011210:Power Plants; D015995:Prevalence; D012111:Residence Characteristics; D045483:Rivers; D012423:Rural Health / Q000706:statistics & numerical data*