title: Proliferative verrucous leukoplakia, squamous cell carcinoma and axillary metastasis.
abstract: Proliferative verrucous leukoplakia (PVL) is an aggressive form of oral leukoplakia with multifocal presentation, high rates of recurrence and malignant transformation. Although development of regional lymph node metastasis is relatively frequent in patients with oral squamous cell carcinoma, axillary metastasis is quite uncommon. This paper presents a case of a 64-year-old female patient who was diagnosed with PVL and developed five oral squamous cell carcinomas and later an axillary lymph node metastasis.
authors.affiliation: Department of Oral Diagnosis, Oral Pathology Section, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo State, Brazil. adrielefg@yahoo.com.br
authors.forename: Adriele-Ferreira
authors.initials: AF
authors.lastname: Gouvêa
authors.forename: Adriana-Elisa-Brasil
authors.initials: AE
authors.lastname: Moreira
authors.forename: Rodrigo-Ribas-Dias
authors.initials: RR
authors.lastname: Reis
authors.forename: Oslei-Paes
authors.initials: OP
authors.lastname: de Almeida
authors.forename: Márcio-Ajudarte
authors.initials: MA
authors.lastname: Lopes
mesh_terms: D001365:Axilla; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary*; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000473:pathology* / Q000556:secondary*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*