A probable association of acute dystonia with gemifloxacin administration.
Gemifloxacin is a recently introduced fluoroquinolone antibiotic frequently used for its broad spectrum and once-daily dosing. Fluoroquinolones are associated with various neuropsychiatric side effects, such as seizures, insomnia, confusion, lightheadedness, psychosis, paranoia and hallucinations. We report a case of a 36-year-old woman given gemifloxacin for an upper respiratory tract infection who developed acute dystonia on the third day following therapy initiation. The clinical implications are discussed.
Sharma
Dinesh Dutt
DD
Department of Psychiatry, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Aggarwal
Ashish
A
Sharma
Ravi C
RC
Kumar
Ramesh
R
D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced* / Q000523:psychology; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects*; D000077735:Gemifloxacin; D006801:Humans; D009287:Naphthyridines / Q000009:adverse effects*; D012141:Respiratory Tract Infections
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; D000077735:Gemifloxacin