title: Two new homoisoflavonoids from the fibrous roots of Ophiopogon japonicus (Thunb.) Ker-Gawl.
abstract: Two new homoisoflavonoids ophiopogonone D (1) and ophiopogonanone G (2) were isolated from the fibrous roots of Ophiopogon japonicus. The structures of these two compounds were determined on the basis of spectroscopic means including HR-ESI-MS, 1D, and 2D NMR experiments. The cytotoxic activities of 1 and 2 against Hela and Hep2 cells are described.
authors.affiliation: School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. changlingd2010@yahoo.com.cn
authors.forename: Chang-Ling
authors.initials: CL
authors.lastname: Duan
authors.forename: Zhi-Yun
authors.initials: ZY
authors.lastname: Kang
authors.forename: Cheng-Ren
authors.initials: CR
authors.lastname: Lin
authors.forename: Yong
authors.initials: Y
authors.lastname: Jiang
authors.forename: Jian-Xun
authors.initials: JX
authors.lastname: Liu
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Tu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031441:Ophiopogon / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D007529:Isoflavones; C548258:ophiopogonanone G; C548257:ophiopogonone D