title: Approaching cellular and molecular resolution of auxin biosynthesis and metabolism.
abstract: There is abundant evidence of multiple biosynthesis pathways for the major naturally occurring auxin in plants, indole-3-acetic acid (IAA), and examples of differential use of two general routes of IAA synthesis, namely Trp-dependent and Trp-independent. Although none of these pathways has been completely defined, we now have examples of specific IAA biosynthetic pathways playing a role in developmental processes by way of localized IAA synthesis, causing us to rethink the interactions between IAA synthesis, transport, and signaling. Recent work also points to some IAA biosynthesis pathways being specific to families within the plant kingdom, whereas others appear to be more ubiquitous. An important advance within the past 5 years is our ability to monitor IAA biosynthesis and metabolism at increasingly higher resolution.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA. normanly@biochem.umass.edu
authors.forename: Jennifer
authors.initials: J
authors.lastname: Normanly
mesh_terms: D029681:Arabidopsis Proteins / Q000378:metabolism; D001692:Biological Transport; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000737:chemistry / Q000378:metabolism*; D008954:Models, Biological; D008956:Models, Chemical; D010455:Peptides / Q000737:chemistry; D018521:Plant Physiological Phenomena; D018517:Plant Roots / Q000378:metabolism; D011506:Proteins / Q000737:chemistry; D015398:Signal Transduction; D014364:Tryptophan / Q000737:chemistry
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D010455:Peptides; D011506:Proteins; C030737:indoleacetic acid; D014364:Tryptophan