Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study.
OBJECTIVE
To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).


METHODS
FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;


RESULTS
No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.


CONCLUSIONS
FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.
Theocharis
Ip
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Ophthalmology Department, Iaso General Hospital, Athens, Greece. ioannistheocharis@hotmail.com