title: Progesterone receptor-mediated up-regulation of transthyretin in preimplantation mouse uterus.
abstract: Transthyretin (TTR), a carrier for thyroxine and retinol, has its messenger RNA (mRNA) expressed in the glandular endometrial epithelium and its protein detected in the glandular endometrial epithelium and the uterine lumen. TTR mRNA is dramatically up-regulated in the preimplantation mouse uterus as well as the P-treated ovariectomized mouse uterus, and in both situations the up-regulation of TTR is blocked by treatment with the P receptor antagonist RU486.
authors.affiliation: Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA.
authors.forename: Honglu
authors.initials: H
authors.lastname: Diao
authors.forename: Shuo
authors.initials: S
authors.lastname: Xiao
authors.forename: Juan
authors.initials: J
authors.lastname: Cui
authors.forename: Jerold
authors.initials: J
authors.lastname: Chun
authors.forename: Ying
authors.initials: Y
authors.lastname: Xu
authors.forename: Xiaoqin
authors.initials: X
authors.lastname: Ye
mesh_terms: D000818:Animals; D010064:Embryo Implantation; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D015735:Mifepristone / Q000494:pharmacology; D011228:Prealbumin / Q000096:biosynthesis*; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology; D049368:Receptors, Lysophosphatidic Acid / Q000235:genetics; D011980:Receptors, Progesterone / Q000502:physiology*; D015854:Up-Regulation; D014599:Uterus / Q000378:metabolism*
chemical_list: C548235:LPAR5 protein, mouse; D011228:Prealbumin; D049368:Receptors, Lysophosphatidic Acid; D011980:Receptors, Progesterone; D015735:Mifepristone; D011374:Progesterone