Canine hippocampal formation composited into three-dimensional structure using MPRAGE.
This study was performed to anatomically illustrate the living canine hippocampal formation in three-dimensions (3D), and to evaluate its relationship to surrounding brain structures. Three normal beagle dogs were scanned on a MR scanner with inversion recovery segmented 3D gradient echo sequence (known as MP-RAGE: Magnetization Prepared Rapid Gradient Echo). The MRI data was manually segmented and reconstructed into a 3D model using the 3D slicer software tool. From the 3D model, the spatial relationships between hippocampal formation and surrounding structures were evaluated. With the increased spatial resolution and contrast of the MPRAGE, the canine hippocampal formation was easily depicted. The reconstructed 3D image allows easy understanding of the hippocampal contour and demonstrates the structural relationship of the hippocampal formation to surrounding structures in vivo.
Jung
Mi-Ae
MA
Department of Veterinary Radiology and Diagnostic Imaging, Konkuk University, Seoul, Korea.
Nahm
Sang-Soep
SS
Lee
Min-Su
MS
Lee
In-Hye
IH
Lee
Ah-Ra
AR
Jang
Dong-Pyo
DP
Kim
Young-Bo
YB
Cho
Zang-Hee
ZH
Eom
Ki-Dong
KD
D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D004285:Dogs / Q000033:anatomy & histology*; D005260:Female; D006624:Hippocampus / Q000033:anatomy & histology* / Q000254:growth & development; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male