title: Early telephone intervention for psychiatric outpatients starting antidepressant treatment.
abstract: BACKGROUND
  The article addresses the hypothesis that early telephone intervention for psychiatric outpatients starting antidepressant treatment would increase compliance with pharmacological treatment and retention time in the study, and thus allow for a more favourable clinical outcome.
  
  
  METHODS
  The study focuses on 131 depressed outpatients who participated in a study aiming to obtain full remission. Patients who benefited from three early structured telephone interventions (n=81) were compared with participants who benefited from the usual care (n=50) with no clinical contact before the first clinical assessment at 2 weeks.
  
  
  RESULTS
  The intervention proved to have no significant effect on treatment adherence, attrition rate, exclusion rate for adverse events or improvement of depression severity. It was nevertheless associated with increased retention time in the present study.
  
  
  CONCLUSIONS
  These results suggest that motivational phone calls may reinforce adhesion in psychiatric patients and provide early opportunities to adapt treatment to individual needs.
  
  
  CONCLUSIONS
  These results suggest that motivational phone calls may reinforce adhesion in psychiatric patients and provide early opportunities to adapt treatment to individual needs.
authors.affiliation: Clinique La Métairie, Avenue de Bois-Bougy, CH-1260 Nyon, Switzerland. ngervasoni@lametairie.ch
authors.forename: Nicola
authors.initials: N
authors.lastname: Gervasoni
authors.forename: Pascaline
authors.initials: P
authors.lastname: Legendre-Simon
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Aubry
authors.forename: Marianne
authors.initials: M
authors.lastname: Gex-Fabry
authors.forename: Gilles
authors.initials: G
authors.lastname: Bertschy
authors.forename: Guido
authors.initials: G
authors.lastname: Bondolfi
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D010045:Outpatients / Q000523:psychology / Q000706:statistics & numerical data*; D017374:Paroxetine / Q000627:therapeutic use*; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data*; D012720:Severity of Illness Index; D012944:Social Support; D013557:Switzerland; D017216:Telemedicine / Q000379:methods*; D013689:Telephone; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine