title: Total Synthesis of Tovophyllin B.
abstract: The first total synthesis of tovophyllin B (2), an antimicrobial xanthone derived from mangosteen, has been accomplished through a convergent strategy from building blocks 6 and 7 involving lithium-mediated coupling, dehydrative cyclization, and 6π electrocyclization as key steps.
authors.affiliation: Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, and Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92037, USA.
authors.forename: Valer
authors.initials: V
authors.lastname: Jeso
authors.forename: K C
authors.initials: KC
authors.lastname: Nicolaou