title: Diffusion-weighted MRI evaluation of breast cancer extension.
abstract: OBJECTIVE
  To investigate the feasibility of using diffusion-weighted MR imaging (DWI) to accurately measure breast cancer extension.
  
  
  METHODS
  The extensions of 59 breast lesions were investigated on DW images and apparent diffusion coefficient (ADC) maps and compared to the pathological exams.
  
  
  RESULTS
  Three groups were observed: accurate, overdiagnosis, and false negative. There were no significant differences seen in accurate or false-negative group when b was 500 and 1000 s/mm(2) when two lesions in the overdiagnosis group at both b values.
  
  
  CONCLUSIONS
  DWI and the ADC value have potential for evaluating cancer extension.
authors.affiliation: Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China.
authors.forename: Qiu
authors.initials: Q
authors.lastname: Long-Hua
authors.forename: Xiao
authors.initials: X
authors.lastname: Qin
authors.forename: Yang
authors.initials: Y
authors.lastname: Wen-Tao
authors.forename: Tang
authors.initials: T
authors.lastname: Feng
authors.forename: Shen
authors.initials: S
authors.lastname: Kun-Wei
authors.forename: Wu
authors.initials: W
authors.lastname: Bin
authors.forename: Gu
authors.initials: G
authors.lastname: Ya-Jia
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity