title: Effectiveness and safety assessment of Mist Tonica, a herbal haematinic.
abstract: Anaemia is a widespread public health problem, and in Ghana it is the fourth leading cause of hospital admissions and the second factor contributing to death. Mist Tonica, an herbal haematinic produced by the Centre for Scientific Research into Plant Medicine (CSRPM), Ghana, was assessed for its effectiveness and safety in humans after Ethics Committee approval. Clinically established anaemic-patients aged, 13 years and above, with haemoglobin levels less than 11.5 g/dl and 13.5 g/dl for females and males respectively were treated with Mist Tonica, 8.96 g/40 mls three times daily for two weeks. The mean haemoglobin rise per week caused by Mist Tonica was 1.92 (0.76) g/dl, range (1.66-2.55) g/dl/week and over 88% of the patients on Mist Tonica had their appetite for food improved. Haematological profile, liver and kidney functions were not adversely affected by Mist Tonica. Results of the study suggest that Mist Tonica is an effective and safe herbal haematinic.
authors.affiliation: Centre for Scientific Research into Plant Medicine, Mampong-Akuapem, Ghana.
authors.forename: Yaw
authors.initials: Y
authors.lastname: Adusi-Poku
authors.forename: Archibald
authors.initials: A
authors.lastname: Sittie
authors.forename: Merlin L K
authors.initials: ML
authors.lastname: Mensah
authors.forename: Kwame
authors.initials: K
authors.lastname: Sarpong
authors.forename: Theophilus C
authors.initials: TC
authors.lastname: Fleischer
authors.forename: Theophilus C
authors.initials: TC
authors.lastname: Ankrah
authors.forename: Dominic
authors.initials: D
authors.lastname: Nsiah