title: Surgical views: Vacuum-assisted wound closure: application and mechanism of action.
abstract: Vacuum-assisted closure (VAC) is a wound management therapy that creates local negative pressure over a wound bed to promote healing. Benefits of VAC therapy include removal of fluid from the extravascular space, improved circulation, enhanced granulation tissue formation, increased bacterial clearance, and hastening of wound closure. This article describes the mechanism of action of VAC therapy, reviews application techniques, and lists potential complications and contraindications.
authors.affiliation: University of Florida, USA.
authors.forename: Kristin
authors.initials: K
authors.lastname: Kirkby
authors.forename: Jason
authors.initials: J
authors.lastname: Wheeler
authors.forename: James
authors.initials: J
authors.lastname: Farese
authors.forename: Gary
authors.initials: G
authors.lastname: Ellison
authors.forename: Nicholas
authors.initials: N
authors.lastname: Bacon
authors.forename: Colin
authors.initials: C
authors.lastname: Sereda
authors.forename: Daniel
authors.initials: D
authors.lastname: Lewis
mesh_terms: D000818:Animals; D003646:Debridement / Q000662:veterinary; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D011312:Pressure; D013536:Suture Techniques / Q000295:instrumentation / Q000662:veterinary*; D014618:Vacuum; D014945:Wound Healing / Q000502:physiology; D014947:Wounds and Injuries / Q000601:surgery / Q000662:veterinary*