Epidemiologic profile of pediatric brain tumors in Morocco.
BACKGROUND
Brain tumors are the most common solid tumors diagnosed among children below 15 years worldwide. However, little is known about the profile of pediatric brain tumors in Africa. The purpose of this study was to further elaborate the epidemiological profile of pediatric brain tumors in Africa, specifically Morocco.


METHODS
A retrospective review was conducted of all patients with primary brain tumors in the age group 0-19 years, from 2003 to 2007, from multiple centers in two cities of Rabat and Casablanca, Morocco. Only patients with histopathological confirmation were included (n = 542). Descriptive epidemiologic profiles were created for the patients by age, sex, and histological subtypes of brain tumors.


RESULTS
Overall medulloblastoma was the most common brain tumor (34.5%), followed by pilocytic astrocytoma (17.3%) and diffuse astrocytoma grade 2 (12.5%). Brain tumors occurred most commonly in 5-9-year age group followed by 10-14-year age group with the former being more common among males and the latter being more common among females. We also found medulloblastoma to be the most common brain tumor in the 0-14-year-olds.


CONCLUSIONS
In this rare study focused on pediatric brain tumors in Morocco, most of the findings were consistent with past studies from other parts of the world. However, we found medulloblastoma to be the most common pediatric brain tumor followed by astrocytoma.
Karkouri
Mehdi
M
Department of Pathology, Centre Hospitalier Universitaire Ibn Rochd, 24 rue Jalal Eddine Essayouti, MA20100 Casablanca, Morocco.
Zafad
Sadia
S
Khattab
Mohammed
M
Benjaafar
Noureddine
N
El Kacemi
Hanan
H
Sefiani
Sana
S
Kettani
Fouad
F
Dey
Subhojit
S
Soliman
Amr S
AS
D000293:Adolescent; D017677:Age Distribution; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009018:Morocco / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult