Microbiology of acute otitis media, Puget Sound region, 2005-2009.
This review of electronic patient records was conducted to identify trends in acute otitis media (AOM) microbiology in the Puget Sound region. Culture results from tympanocentesis procedures performed between July 1, 2005 and June 30, 2009 were compiled into 4 respiratory disease seasons: 2005-2006, 2006-2007, 2007-2008, 2008-2009. Heptavalent pneumococcal conjugate vaccination coverage within the cohort was 85%; average patient age was 13 months (SD = 6.6). The proportion of AOM isolates positive for Streptococcus pneumoniae for the four periods covered was 48%, 41%, 35%, and 54%, respectively (P = 0.185, 3rd to 4th season). For Haemophilus influenzae, the proportions were 42%, 41%, 59%, and 38%, respectively (P = 0.182, 3rd to 4th season). Penicillin resistance among S pneumoniae isolates increased from 13% to 61% across the study period (P = 0.016). S pneumoniae may be regaining prevalence as an otopathogen in PCV7-vaccinated populations, and levels of penicillin resistance are increasing.
Grubb
Mark S
MS
Woodcreek Healthcare Inc, 1706 Meridian S., Puyallup, WA 98371, USA mgrubb@u.washington.edu
Spaugh
David C
DC
D000208:Acute Disease; D002675:Child, Preschool; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D016347:Medical Records Systems, Computerized; D010034:Otitis Media with Effusion / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology*; D010403:Penicillin Resistance; D015995:Prevalence; D012189:Retrospective Studies; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*; D014861:Washington / Q000453:epidemiology