Radiation dose-volume effects of the urinary bladder.
An in-depth overview of the normal-tissue radiation tolerance of the urinary bladder is presented. The most informative studies consider whole-organ irradiation. The data on partial-organ/nonuniform irradiation are suspect because the bladder motion is not accounted for, and many studies lack long enough follow-up data. Future studies are needed.
Viswanathan
Akila N
AN
Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. aviswanathan@lroc.harvard.edu
Yorke
Ellen D
ED
Marks
Lawrence B
LB
Eifel
Patricia J
PJ
Shipley
William U
WU
D005260:Female; D005544:Forecasting; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D008297:Male; D008954:Models, Biological; D009068:Movement; D011468:Prostatectomy / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries / Q000150:complications*; D011836:Radiation Tolerance; D011859:Radiography; D011879:Radiotherapy Dosage; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000528:radiation effects*; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy