Synthesis of the 6'-iso analogues of neplanocin A and 5'-homoneplanocin A.
An efficient synthesis of 6'-isoneplanocin A and 6-isohomoneplanocin A is reported. The key steps in the synthesis include an enyne metathesis and a regioselective oxidation.
Ye
Wei
W
Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 36849-5312.
He
Mingzhu
M
Schneller
Stewart W
SW