Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study.
OBJECTIVE
The effect of a Pelvicol graft compared with a conventional anterior vaginal repair was evaluated in this randomised controlled study.


METHODS
Only patients with a stage II or higher (Ba >or= -1) defect were included.


RESULTS
Thirty-one patients were allocated to a conventional anterior repair; 30 to Pelvicol graft. At 12 months follow-up, four patients among controls (15%) and two in the graft group (7%) had objective recurrence. Among controls, the difference at 3 months follow-up in Ba was 6.0 cm when compared with the position of Ba prior to surgery. In the graft group, the difference was 7.0 cm (P < 0.05). This difference was still present at 12 months follow-up (6.0 vs. 7.0 cm; P < 0.05).


CONCLUSIONS
The implantation of a Pelvicol graft does not improve the POP-Q stage.
Hviid
Ulla
U
Department of Obstetrics and Gynaecology, Roskilde University Hospital, Roskilde, Denmark.
Hviid
Thomas Vauvert F
TV
Rudnicki
Martin
M
D000818:Animals; D001705:Bioprosthesis; D003094:Collagen; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D016038:Skin Transplantation; D013552:Swine; D014596:Uterine Prolapse / Q000601:surgery*
D003094:Collagen