[Diagnosis and treatment of coincident vesical transitional cell carcinoma and prostate cancer: a report of 5 cases].
OBJECTIVE
To improve the diagnosis and treatment of coincident vesical transitional cell carcinoma (VTCC) and prostate cancer.


METHODS
We analyzed the clinical data of 5 cases of coincident VTCC and prostate cancer.


RESULTS
The 5 patients, at the mean age of 66.2 years, were diagnosed as having grade II - III VTCC by cystoscopy and biopsy, 1 with a history of prostate cancer, and the other 4 with prostate cancer confirmed by postoperative pathological examination. Two of the patients were treated by radical cystoprostatectomy, 1 by radical cystoprostatectomy and ileum conduit surgery, 1 by transurethral resection of bladder tumor, and the other 1 by palliative ureterocutaneostomy due to cardiopulmonary problems. The follow-up lasted 8 -26 months. One of them died of diffused metastasis 20 months after surgery, 1 survived with the tumor untreated, and the other 3 remained tumor free.


CONCLUSIONS
Coincident VTCC and prostate cancer is easy to be missed in diagnosis. PSA detection, rectal palpation, transrectal ultrasonography, biopsy, and cystoscopy are the main diagnostic options for this disease. Its treatment should be based on the classification and clinical staging of the two cancers. Coincident VTCC and prostate cancer does not suggest poor prognosis.
Song
Yong-Sheng
YS
Department of Urology, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110004, China. song-ys@sj-hospital.org
Song
Yan
Y
Luo
Jin-Yu
JY
Wu
Bin
B
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery