title: [Cryptococcemia with a severe bronchial asthma: case report and review of the literature].
abstract: A 64-year old hospitalized male for severe bronchial asthma began to complain fatigue and appetite loss. His asthma had been treated with oral bethamethasone. The Chest CT at this time revealed a bilateral consolidation of the lower lung. Despite a week of treatment with antibiotics and anti-fungals, the patient expired from DIC progression. His premortem sputum and blood culture grew Cryptococcus Neoformans. We concluded his diagnosis as cryptococcal pneumonia and sepsis. Sepsis by Cryptococcus neoformans is a rare clinical event, and only 20 cases have been reported in Japan. Although 16 of the 20 had preexisting medical conditions, a case with underlying bronchial asthma has never been reported. A comparison of the reported cases of the US and Europe to that of Japan revealed differences in the patients' underlying conditions. We report a case with a brief review of the literature and summarize the 20 cases that have been reported in Japan.
authors.affiliation: Department of Pulmonology, Kameda Medical Center.
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Ando
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ohkuni
authors.forename: Masafumi
authors.initials: M
authors.lastname: Misawa
authors.forename: Daisaku
authors.initials: D
authors.lastname: Yasui
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Asai
authors.forename: Takuya
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Kei
authors.initials: K
authors.lastname: Nakashima
authors.forename: Ryo
authors.initials: R
authors.lastname: Matsunuma
authors.forename: Norihiro
authors.initials: N
authors.lastname: Kaneko
authors.forename: Makoto
authors.initials: M
authors.lastname: Narita
mesh_terms: D018927:Anti-Asthmatic Agents / Q000009:adverse effects*; D001249:Asthma / Q000150:complications* / Q000188:drug therapy*; D001623:Betamethasone / Q000009:adverse effects*; D003453:Cryptococcosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018805:Sepsis / Q000209:etiology*
chemical_list: D018927:Anti-Asthmatic Agents; D001623:Betamethasone