title: Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent.
abstract: meso-Octamethyloctafluorocalixpyrrole, a simple tetrapyrrolic macrocycle, has been shown to function as both a chloride/nitrate and a chloride/bicarbonate antiport agent for lipid bilayer transmembrane anion transport. This is the first example of a synthetic macrocyclic pyrrole-based receptor capable of transmembrane bicarbonate transport.
authors.affiliation: School of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom. philip.gale@soton.ac.uk
authors.forename: Philip A
authors.initials: PA
authors.lastname: Gale
authors.forename: Christine C
authors.initials: CC
authors.lastname: Tong
authors.forename: Cally J E
authors.initials: CJ
authors.lastname: Haynes
authors.forename: Olubukunola
authors.initials: O
authors.lastname: Adeosun
authors.forename: Dustin E
authors.initials: DE
authors.lastname: Gross
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Karnas
authors.forename: Elaine M
authors.initials: EM
authors.lastname: Sedenberg
authors.forename: Roberto
authors.initials: R
authors.lastname: Quesada
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Sessler
mesh_terms: D000838:Anions / Q000737:chemistry; D001639:Bicarbonates / Q000737:chemistry; D047250:Calixarenes / Q000737:chemistry* / Q000494:pharmacology; D027963:Chloride-Bicarbonate Antiporters / Q000737:chemistry* / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry; D009566:Nitrates / Q000737:chemistry; D010713:Phosphatidylcholines / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry* / Q000494:pharmacology; D012965:Sodium Chloride / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry
chemical_list: D000838:Anions; D001639:Bicarbonates; D027963:Chloride-Bicarbonate Antiporters; D008051:Lipid Bilayers; D009566:Nitrates; D010713:Phosphatidylcholines; D011166:Porphyrins; D013431:Sulfates; C469811:calix(4)pyrrole; C550129:octafluorocalix(4)pyrrole; C012036:sodium sulfate; D047250:Calixarenes; D012965:Sodium Chloride; C028694:1-palmitoyl-2-oleoylphosphatidylcholine