title: Syntheses of protoporphyrin-IX derivatives bearing extended propionate side-chains.
abstract: In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.
authors.forename: Robert T
authors.initials: RT
authors.lastname: Holmes
authors.forename: Jianming
authors.initials: J
authors.lastname: Lu
authors.forename: Celinah
authors.initials: C
authors.lastname: Mwakwari
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Smith