title: Anesthetic management of a patient with an allergy to propylene glycol and parabens.
abstract: Multiple pharmaceutical products contain excipients, or additive chemicals, to improve stability, bioavailability, antimicrobial activity, or palatability. Two of the most common excipients are propylene glycol and parabens. We report the successful anesthetic management of a patient with idiosyncratic reactions to prescribed and over-the-counter medications containing propylene glycol and parabens.
authors.affiliation: Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Michaela K
authors.initials: MK
authors.lastname: Farber
authors.forename: Tiffany E
authors.initials: TE
authors.lastname: Angelo
authors.forename: Mariana
authors.initials: M
authors.lastname: Castells
authors.forename: Lawrence C
authors.initials: LC
authors.lastname: Tsen
mesh_terms: D000328:Adult; D000698:Analgesia; D000768:Anesthesia, General; D000775:Anesthesia, Spinal; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005079:Excipients / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007428:Intradermal Tests; D007889:Leiomyoma / Q000601:surgery*; D010226:Parabens / Q000009:adverse effects*; D019946:Propylene Glycol / Q000009:adverse effects*; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000601:surgery*
chemical_list: D005079:Excipients; D010226:Parabens; D019946:Propylene Glycol