The current status of image-guided external beam radiotherapy for prostate cancer.
OBJECTIVE
To assess the current status and technological advances in image-guided external beam radiotherapy for prostate cancer.


RESULTS
Modern imaging has improved the ability to define radiotherapy target volumes. Specifically, treatment margins have been reduced through the use of treatment planning and image-guidance technology. Increasing dose has led to increased disease control. Concurrent technological advances may improve treatment-related toxicity. Data continues to emerge on patient selection, treatment schedule, and use of additional systemic therapy in conjunction with radiation.


CONCLUSIONS
In the present article, we review recent developments in radiation planning, image guidance, patient selection and fractionation, dose escalation, toxicity, systemic therapy, and follow-up.
Stephans
Kevin L
KL
Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. stephak@ccf.org
Xia
Ping
P
Tendulkar
Rahul D
RD
Ciezki
Jay P
JP
D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008297:Male; D018579:Patient Selection; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011878:Radiotherapy / Q000379:methods* / Q000639:trends*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome