title: Substantial formation of hydrates and hemiacetals from pyridinium ketones.
abstract: Pyridinium ketones have been found to exist as hydrates and hemiacetals in considerable amount in aqueous and alcoholic solutions, respectively. The relative position of the pyridinium positive charge has a large effect on the equilibrium constants. The polar substituent constants, sigma*, of the pyridinium group substituted at different positions can be estimated from the hydration constants.
authors.affiliation: Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, United States.
authors.forename: Sha
authors.initials: S
authors.lastname: Huang
authors.forename: Amanda K
authors.initials: AK
authors.lastname: Miller
authors.forename: Weiming
authors.initials: W
authors.lastname: Wu