Reduction of increased repetitive self-grooming in ASD mouse model by metabotropic 5 glutamate receptor antagonism; randomized controlled trial of Early Start Denver Model.
Cook
Edwin H
EH
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA. ecook@psych.uic.edu
D000818:Animals; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D002675:Child, Preschool; D003142:Communication; D003479:Curriculum; D004195:Disease Models, Animal; D004311:Double-Blind Method; D018479:Early Intervention, Educational / Q000379:methods*; D005500:Follow-Up Studies; D006120:Grooming / Q000187:drug effects*; D006801:Humans; D007223:Infant; D051379:Mice; D009048:Motor Skills / Q000187:drug effects; D010552:Personality Assessment; D011725:Pyridines / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D064529:Receptor, Metabotropic Glutamate 5; D018094:Receptors, Metabotropic Glutamate / Q000037:antagonists & inhibitors*; D012951:Socialization; D013239:Stereotyped Behavior / Q000187:drug effects*
D011725:Pyridines; D064529:Receptor, Metabotropic Glutamate 5; D018094:Receptors, Metabotropic Glutamate; C121465:6-methyl-2-(phenylethynyl)pyridine