4'-O-methylglycosylation of curcumin by Beauveria bassiana.
The applications of curcumin have been limited by its poor water solubility and low bioavailability. In this study, we successfully synthesized a new curcumin derivative, curcumin-8'-O-4"-O-methyl-beta-D-glucopyranoside, by biotransformation with the fungal strain Beauveria bassiana ATCC 7159. The structure of this new product was determined on the basis of spectroscopic data. This is the first record of a curcumin glycoside that has been synthesized by a fungus.
Zeng
Jia
J
Department of Biological and Irrigation Engineering, Utah State University, Logan, UT 84322-4105, USA.
Yang
Nan
N
Li
Xiu-Min
XM
Shami
Paul J
PJ
Zhan
Jixun
J
D052982:Beauveria / Q000378:metabolism*; D001711:Biotransformation; D003474:Curcumin / Q000378:metabolism*; D006031:Glycosylation
D003474:Curcumin