Peri- and intra-operative management of the goat during acute surgical experimentation.
Goats are used as animal models for surgery and trauma research. The authors discuss appropriate methods for induction of anesthetics, intubation and surgical maintenance of the goat during acute experimentation. Risks imposed by the Q fever pathogen Coxiella burnetii are described, as well as measures that have proven effective in minimizing zoonotic transmission of this pathogen to laboratory personnel. With appropriate knowledge of its applications, peri- and intra-operative management and limitations, the goat is a suitable animal model for a variety of biomedical research applications.
Flaherty
Devin C
DC
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX, USA.
Hoxha
Besim
B
Nelson
Shirley
S
Sun
Jie
J
Gurji
Hunaid
H
Simecka
Jerry W
JW
Mallet
Robert T
RT
Olivencia-Yurvati
Albert H
AH
Daniels
Egeenee Q
EQ
D000758:Anesthesia / Q000379:methods / Q000662:veterinary; D000818:Animals; D006041:Goats / Q000601:surgery*; D007430:Intraoperative Care / Q000379:methods / Q000662:veterinary*; D007442:Intubation, Intratracheal / Q000379:methods / Q000662:veterinary; D023421:Models, Animal; D011300:Preoperative Care / Q000379:methods / Q000662:veterinary; D012771:Shock, Hemorrhagic / Q000601:surgery / Q000662:veterinary*; D013514:Surgical Procedures, Operative / Q000379:methods / Q000662:veterinary*