title: Lung abscess in adults with tetralogy of fallot and pulmonary atresia.
abstract: We describe 5 adults with tetralogy of Fallot and pulmonary atresia who developed lung abscesses, including some infected with atypical microbial pathogens, with important morbidity. We hypothesize that patients with such anatomy are at risk for chronic pulmonary infection due to hypo-perfusion of the pulmonary parenchyma. This previously unreported clinical association should be considered in the differential diagnosis of patients with tetralogy of Fallot and pulmonary atresia who alter their respiratory state.
authors.affiliation: Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
authors.forename: Clare P
authors.initials: CP
authors.lastname: O'Donnell
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Landzberg
authors.forename: Mary P
authors.initials: MP
authors.lastname: Mullen
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000601:surgery*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D004322:Drainage / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008169:Lung Abscess / Q000000981:diagnostic imaging* / Q000382:microbiology* / Q000401:mortality / Q000628:therapy; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy; D018633:Pulmonary Atresia / Q000175:diagnosis / Q000601:surgery*; D018570:Risk Assessment; D012494:Sampling Studies; D013771:Tetralogy of Fallot / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents