Chemoselective glycosylations using 2,3-unsaturated-4-keto glycosyl donors.
2,3-Unsaturated-4-keto glycosyl acetates were found to exhibit low reactivity under several glycosylation conditions. Chemoselective glycosylations were effectively performed using 2,3-unsaturated glycosyl and 2,3-dideoxy glycosyl acetates as armed glycosyl donors, and 2,3-unsaturated-4-keto glycosyl acetates as disarmed glycosyl donors.
Kusumi
Shunichi
S
Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Wang
Sainan
S
Watanabe
Tatsuya
T
Sasaki
Kaname
K
Takahashi
Daisuke
D
Toshima
Kazunobu
K