Hepatocellular carcinoma: epidemiology, surveillance, and diagnosis.
Hepatocellular carcinoma (HCC) is increasing in incidence in many countries, and is the most common cause of death in patients with cirrhosis. With regular surveillance, small early HCC lesions can be identified. An algorithm has been developed that allows for diagnosis of these lesions. Very early HCC lesions have high cure rates with appropriate treatment. If all these factors are in place most HCCs can be cured.
Sherman
Morris
M
Department of Medicine, University of Toronto and University Health Network, Toronto, Canada. morris.sherman@uhn.on.ca
D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy / Q000821:virology; D003131:Combined Modality Therapy; D055088:Early Detection of Cancer; D005260:Female; D019694:Hepatitis B, Chronic / Q000473:pathology; D019698:Hepatitis C, Chronic / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy / Q000821:virology; D008297:Male; D019370:Observation; D011230:Precancerous Conditions / Q000473:pathology*; D011379:Prognosis; D018570:Risk Assessment; D016019:Survival Analysis