title: Evidence that a West-East admixed population lived in the Tarim Basin as early as the early Bronze Age.
abstract: BACKGROUND
  The Tarim Basin, located on the ancient Silk Road, played a very important role in the history of human migration and cultural communications between the West and the East. However, both the exact period at which the relevant events occurred and the origins of the people in the area remain very obscure. In this paper, we present data from the analyses of both Y chromosomal and mitochondrial DNA (mtDNA) derived from human remains excavated from the Xiaohe cemetery, the oldest archeological site with human remains discovered in the Tarim Basin thus far.
  
  
  RESULTS
  Mitochondrial DNA analysis showed that the Xiaohe people carried both the East Eurasian haplogroup (C) and the West Eurasian haplogroups (H and K), whereas Y chromosomal DNA analysis revealed only the West Eurasian haplogroup R1a1a in the male individuals.
  
  
  CONCLUSIONS
  Our results demonstrated that the Xiaohe people were an admixture from populations originating from both the West and the East, implying that the Tarim Basin had been occupied by an admixed population since the early Bronze Age. To our knowledge, this is the earliest genetic evidence of an admixed population settled in the Tarim Basin.
authors.affiliation: Ancient DNA Laboratory, Research Center for Chinese Frontier Archaeology, Jilin University, Changchun 130012, PR China.
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Li
authors.forename: Hongjie
authors.initials: H
authors.lastname: Li
authors.forename: Yinqiu
authors.initials: Y
authors.lastname: Cui
authors.forename: Chengzhi
authors.initials: C
authors.lastname: Xie
authors.forename: Dawei
authors.initials: D
authors.lastname: Cai
authors.forename: Wenying
authors.initials: W
authors.lastname: Li
authors.forename: Victor H
authors.initials: VH
authors.lastname: Mair
authors.forename: Zhi
authors.initials: Z
authors.lastname: Xu
authors.forename: Quanchao
authors.initials: Q
authors.lastname: Zhang
authors.forename: Idelisi
authors.initials: I
authors.lastname: Abuduresule
authors.forename: Li
authors.initials: L
authors.lastname: Jin
authors.forename: Hong
authors.initials: H
authors.lastname: Zhu
authors.forename: Hui
authors.initials: H
authors.lastname: Zhou
mesh_terms: D001106:Archaeology; D002681:China; D041322:Chromosomes, Human, Y / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics; D005260:Female; D005828:Genetics, Population / Q000266:history*; D005843:Geography; D006239:Haplotypes; D049690:History, Ancient; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction
chemical_list: D004272:DNA, Mitochondrial