title: Central neurocytoma presenting with massive hemorrhage leading to coma--case report.
abstract: A 21-year-old man presented with a hemorrhagic central neurocytoma manifesting as acute onset of disturbance of consciousness and right hemiparesis. Computed tomography (CT) demonstrated a tumor in the left lateral ventricle during the course of evaluation for mental alteration 12 days before onset, but the tumor was left untreated because the patient refused to visit a neurosurgical institution. CT on admission revealed a large mass lesion located in the body of the lateral ventricle associated with massive intratumoral and intraventricular hemorrhage. He underwent emergent surgery for evacuation of the tumor with hematoma, and his neurological symptoms gradually recovered after surgery. The present case highlights the possibility of rapid deterioration of symptoms by massive hemorrhage from central neurocytoma. Surgical intervention should thoroughly be considered, if intratumoral hemorrhage is present, as hemorrhage from the central neurocytoma may lead to serious neurological complications.
authors.affiliation: Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka. terakawa@msic.med.osaka-cu.ac.jp
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Terakawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Tsuruno
authors.forename: Kenichi
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Okada
authors.forename: Katsumi
authors.initials: K
authors.lastname: Shimotake
authors.forename: Takaho
authors.initials: T
authors.lastname: Murata
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology*; D002551:Cerebral Ventricle Neoplasms / Q000098:blood supply / Q000150:complications / Q000473:pathology*; D003128:Coma / Q000209:etiology*; D018450:Disease Progression; D004632:Emergency Medical Services / Q000379:methods / Q000592:standards; D006801:Humans; D020547:Lateral Ventricles / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D018306:Neurocytoma / Q000098:blood supply / Q000150:complications / Q000473:pathology*; D019635:Neurosurgical Procedures; D010291:Paresis / Q000209:etiology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014696:Ventriculostomy; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor