Copper-catalyzed chlorination of functionalized arylboronic acids.
A mild, efficient, Cu(I)-catalyzed method for the conversion of arylboronic acids to aryl chlorides is reported. This method is particularly useful for the conversion of electron-deficient arylboronic acids to aryl chlorides, a transformation that is inefficient in the absence of Cu catalysis.
Wu
Hong
H
Discovery Chemistry, Bristol-Myers Squibb Company, PO Box 4000, Princeton New Jersey 08543, USA.
Hynes
John
J
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D001897:Boronic Acids; D006843:Hydrocarbons, Chlorinated; D003300:Copper