Quantitative and morphometric changes of subpopulations of myenteric neurons in swines with toxoplasmosis.
The consequences of the infection caused by Toxoplasma gondii in myenteric neurons of the jejunum of swines reactive to NADH-diaphorase and NADPH-diaphorase were evaluated in this study. Ten 88-day-old mixed-breed swines (Pietrain and Wessex) were assigned into two groups: Control (n=5) and Experimental (n=5), which orally received 5000 sporulated oocysts from a genotype III T. gondii strain. After 30days, the animals were anesthetized, having part of their jejunum removed and stained with NADPH-diaphorase and NADH-diaphorase. NADPHd-p neurons (nitrergic) presented increase of the number of cells per ganglion and hypertrophy. The number of NADHd-p neurons (metabolic more active) and their nuclear area decreased.
Odorizzi
Leandro
L
Programa de Pós-Graduação em Ciência Animal, Universidade Paranaense, PR, Brazil.
Moreira
Neide Martins
NM
Gonçalves
Gentil Ferreira
GF
da Silva
Aristeu Vieira
AV
Sant'ana
Débora de Mello Gonçales
Dde M
Araújo
Eduardo José de Almeida
EJ
D000818:Animals; D008058:Dihydrolipoamide Dehydrogenase / Q000096:biosynthesis; D015870:Gene Expression; D009197:Myenteric Plexus / Q000201:enzymology / Q000473:pathology*; D009252:NADPH Dehydrogenase / Q000096:biosynthesis; D009474:Neurons / Q000201:enzymology / Q000473:pathology*; D013552:Swine; D014124:Toxoplasmosis, Animal / Q000201:enzymology / Q000473:pathology*
D009252:NADPH Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase