title: Simultaneous determination of seven neonicotinoid pesticide residues in food by ultraperformance liquid chromatography tandem mass spectrometry.
abstract: The present study developed an improved analytical method for simultaneous quantification of seven neonicotinoids in food by ultraperformance liquid chromatography combined with electrospray ionization triple quadrupole tandem mass spectrometry (UPLC-MS/MS) under the multiple reaction monitoring (MRM) mode. The optimization of extraction, cleanup, UPLC separation and MS/MS parameters of analytes were especially focused on. The low limits of quantification (LOQs) of neonicotinoids ranged from 0.1 to 6 microg kg(-1). Meanwhile, reasonable recoveries (65-120%) of seven neonicotinoids for food including apple, cabbage, potato, rice, tea, milk, chicken, pork and egg were demonstrated in different spiked levels within their respective linear range (0.025-150 microg kg(-1)). The developed analytical method would be appropriate for the routine, high throughput, high sensitivity quantification of seven neonicotinoids using simple sample pretreatment.
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, P. R. China.
authors.forename: Shaoying
authors.initials: S
authors.lastname: Liu
authors.forename: Zuntao
authors.initials: Z
authors.lastname: Zheng
authors.forename: Fanglin
authors.initials: F
authors.lastname: Wei
authors.forename: Yiping
authors.initials: Y
authors.lastname: Ren
authors.forename: Wenjun
authors.initials: W
authors.lastname: Gui
authors.forename: Huiming
authors.initials: H
authors.lastname: Wu
authors.forename: Guonian
authors.initials: G
authors.lastname: Zhu
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005504:Food Analysis; D057230:Limit of Detection; D008460:Meat / Q000032:analysis; D010573:Pesticide Residues / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014675:Vegetables / Q000737:chemistry
chemical_list: D010573:Pesticide Residues