title: Consequences of aggressive behavior in patients with dementia.
abstract: This study examined aggression as a predictor of nursing-home placement, injuries, use of restraints, and use of health services in community-dwelling patients with newly diagnosed dementia. Participants were identified from 2001-2004 Veterans Administration databases; all had a new diagnosis of dementia and no aggression. Patients and caregivers were evaluated for aggression, using the Cohen-Mansfield Agitation Inventory-aggression subscale, and other outcomes for 2 years, with outcome rates compared between patients who did or did not develop aggression and between pre- and postaggressive periods. Of 215 patients, 88 became aggressive, associated with significantly increased use of psychotropic medication (p< or =0.04), injuries (p< or =0.0001), and nursing-home placement (p< or =0.004).
authors.affiliation: Houston Center for Quality of Care & Utilization Studies, Houston, TX 77030, USA. mkunik@bcm.tmc.edu
authors.forename: Mark E
authors.initials: ME
authors.lastname: Kunik
authors.forename: A Lynn
authors.initials: AL
authors.lastname: Snow
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Davila
authors.forename: Thomas
authors.initials: T
authors.lastname: McNeese
authors.forename: Avila B
authors.initials: AB
authors.lastname: Steele
authors.forename: Valli
authors.initials: V
authors.lastname: Balasubramanyam
authors.forename: Rachelle
authors.initials: R
authors.lastname: Doody
authors.forename: Paul E
authors.initials: PE
authors.lastname: Schulz
authors.forename: Jagadeesh S
authors.initials: JS
authors.lastname: Kalavar
authors.forename: Annette
authors.initials: A
authors.lastname: Walder
authors.forename: Robert O
authors.initials: RO
authors.lastname: Morgan
mesh_terms: D000368:Aged; D000374:Aggression / Q000523:psychology*; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003156:Community Mental Health Services / Q000706:statistics & numerical data; D003704:Dementia / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009735:Nursing Homes / Q000706:statistics & numerical data; D011595:Psychomotor Agitation / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011795:Surveys and Questionnaires
chemical_list: D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents