title: Early unilateral macular sensitivity changes in microperimetry in a case of pituitary adenoma.
abstract: The value of the MP-1 microperimeter in early diagnosis of pituitary tumours by detection of changes in macular sensitivity is described. A 21-year-old female presented with blurred vision in the right eye. Ophthalmic examination was unremarkable. Static perimetry of the central visual field (30°) was performed by use of a Humphrey automatic perimeter, and the retinal sensitivity of the 12 central degrees was measured by use of the MP-1. Static perimetry revealed a peripheral visual field defect without involvement of the macular region. The MP-1 revealed an important loss of sensitivity (3.4 ± 4.8 dB) in the central 12°. Magnetic resonance imaging revealed a pituitary adenoma with sellar and suprasellar extension. Three months after surgical removal, use of the MP-1 revealed complete recovery of the sensitivity (19.28 ± 2.5 dB), fixation location, and fixation stability of the right eye. In pituitary tumours, the presence of a sub-clinical form of macular involvement can be demonstrated and followed-up accurately by use of the MP-1.
authors.affiliation: St. Paul's Eye Unit, Royal Liverpool University Hospital, Prescot Street, L7 8XP, Liverpool, UK. romanomario@email.it
authors.forename: M R
authors.initials: MR
authors.lastname: Romano
authors.forename: Martina
authors.initials: M
authors.lastname: Angi
authors.forename: Vito
authors.initials: V
authors.lastname: Romano
authors.forename: Joaquin
authors.initials: J
authors.lastname: Marticorena
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Romano
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D011184:Postoperative Period; D020127:Recovery of Function; D014786:Vision Disorders / Q000209:etiology; D058609:Visual Field Tests / Q000379:methods*; D055815:Young Adult