Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report.
We report a case of chronic lymphocytic leukemia with a characteristic cytogenetics finding detected by fluorescent in situ hybridization. This case has deletion in p53 gene in 50% of interphase nuclei studied in the peripheral blood and polyploidy in 30% of cells. To our knowledge polyploidy is not commonly reported with chronic lymphocytic leukemia patients.
Eid
Maha
M
Department of Cytogenetics, National Research Centre, El-Tahreer Street, Dokki, Cairo, Egypt. mahaeid67@gmail.com
Kayed
Hesham
H
El-Bassyouni
Hala T
HT