title: A novel norditerpenoid alkaloid from Aconitum macrorhynchum.
abstract: A novel norditerpenoid alkaloid, macrorhynine C (1), together with three known compounds, was isolated from Aconitum macrorhynchum. The structure of the new alkaloid was elucidated on the basis of spectral analyses as (1alpha,6alpha,16beta)-3-hydroxy-8-acetyloxy-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-19-ene-aconitan-14-yl 4-methoxybenzoate (1). The novel compound was found to contain the rare C(19) = N azomethine group. Compounds 2-4 were obtained from this species for the first time.
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, China.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Yang
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Luo
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.forename: Jing-Feng
authors.initials: JF
authors.lastname: Zhao
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Yang
authors.forename: Liang
authors.initials: L
authors.lastname: Li
mesh_terms: D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004224:Diterpenes; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C547644:macrorhynine C