[Specifics of individual risks in a group of women with genital neoplasms].
Genital cancers represent an important issue regarding women health, as they produce a large number of cases, invalidities and deaths.


OBJECTIVE
The evaluation of individual risks for a group of women with genital neoplasia.


METHODS
We conducted a pilot case-control study to validate the questionnaire for the evaluation of risk factors in genital cancers, in a number of 40 female subjects (20 cases and 20 controls). We have realized the data processing using the SPSS 16 and EpiInfo 3.5.1. soft wares.


RESULTS
For questionnaire validation we have evaluated the reproducibility, the validity, the acceptability and the practicability of the questionnaire. In order to establish the test reproducibility, we have calculated k factors for inter-investigator (k = 0.34) and intra-investigator (k = 0.72) variation. To evaluate the questionnaire validity we calculated the sensitivity (cases = 94%; controls = 97%), specificity (cases = 67%, controls = 75%), positive predictive value (cases = 94%; controls = 94%), negative predictive value (cases = 67%; controls = 86%). The risk factors most frequently identified were genital infectious in clinical records (75% comparing to 52.5% - p = 0.036), and also the presence of other pathological records in genital area (65% comparing to 22.5% - p = 0.0001).


CONCLUSIONS
For an accurate identification of individual risk at women with genital cancers subsequently studies on greater number of subjects is necessary.
Matei
Mioara
M
Disciplina de Asistenţa Primară a Stării de Sănătate si Epidemiologie, Facultateă de Medicină, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Negură
L
L
Carasevici
E
E
Azoicăi
Doina
D
D000328:Adult; D000368:Aged; D000465:Algorithms; D016022:Case-Control Studies; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000209:etiology; D010865:Pilot Projects; D011237:Predictive Value of Tests; D015995:Prevalence; D015203:Reproducibility of Results; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000209:etiology