title: [The withdrawal syndrome in benzodiazepine dependence and its management].
abstract: The authors present the result of an observational study about the withdrawal syndrome in benzodiazepine dependence, and the aspect of identifying withdrawal symptoms, effective communication with the patient and the structure of withdrawal programmes.
  
  
  METHODS
  The study included a number of 22 pacients hospitalised in the Drug-Dependence Clinic of Iaşi between January 2006 - December 2008.
  
  
  RESULTS
  The present article consists of data covering current issues in the area of withdrawal syndrome in benzodiazepine dependence. The most prescribed benzodiazepines were diazepam (10 cases), followed by alprazolam (5 cases) and nitrazepam (4 cases). The clinical manifestations such as anxiety, insomnia, concentration problems, fatigability were present at all patients.
authors.affiliation: Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi. Facultatea de Medicină, Disiciplina de Psihiatrie, Spitalul Clinic de Psihiatrie "Socola" Iaşi.
authors.forename: A O
authors.initials: AO
authors.lastname: Străulea
authors.forename: V
authors.initials: V
authors.lastname: Chiriţă
mesh_terms: D000328:Adult; D000368:Aged; D000525:Alprazolam / Q000009:adverse effects; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001007:Anxiety / Q000209:etiology; D001008:Anxiety Disorders / Q000188:drug therapy; D001247:Asthenia / Q000209:etiology; D001569:Benzodiazepines / Q000008:administration & dosage / Q000009:adverse effects*; D003072:Cognition Disorders / Q000209:etiology; D003975:Diazepam / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009567:Nitrazepam / Q000009:adverse effects; D010819:Physician's Role; D012064:Relaxation Therapy / Q000379:methods; D012189:Retrospective Studies; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology; D013375:Substance Withdrawal Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D009567:Nitrazepam; D003975:Diazepam; D000525:Alprazolam