Human decidual NK cells from gravid uteri and NK cells from cycling endometrium are distinct NK cell subsets.
Human NK cells from the decidua basalis of gravid uteri and from the cycling endometrium of women undergoing hysterectomy were isolated and compared by gene expression profiling using Affymetrix microarrays with probes representing approximately 47,400 transcripts. Substantial differences indicate that these two types of NK cells represent distinct subsets.
Kopcow
H D
HD
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Eriksson
M
M
Mselle
T F
TF
Damrauer
S M
SM
Wira
C R
CR
Sentman
C L
CL
Strominger
J L
JL
D002469:Cell Separation; D003656:Decidua / Q000276:immunology*; D004717:Endometrium / Q000276:immunology*; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology / Q000378:metabolism*; D016131:Lymphocyte Subsets / Q000378:metabolism*; D011247:Pregnancy / Q000276:immunology; D014599:Uterus / Q000276:immunology*