title: Microwave-Assisted Direct Biaryl Coupling: First Application to the Synthesis of Aporphines.
abstract: We have investigated the use of microwaves in a direct biaryl coupling reaction for the synthesis of analogs of the aporphine alkaloid nantenine. Our study shows that the aporphine core may be rapidly accessed from benzyl-tetrahydroisoquinoline substrates with this method. This is the first report of a microwave-assisted direct biaryl coupling reaction in the synthesis of aporphine molecules.
authors.affiliation: Dept. of Chemistry, Hunter College, and the Graduate Center of the City University of New York, 695 Park Avenue, New York, NY 10065, USA.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Chaudhary
authors.forename: Stevan
authors.initials: S
authors.lastname: Pecic
authors.forename: Onica
authors.initials: O
authors.lastname: Legendre
authors.forename: Wayne W
authors.initials: WW
authors.lastname: Harding