title: Effects of the application of intra-abdominal low pressure on laparoscopic cholecystectomy on acid-base equilibrium.
abstract: The objective of this study was to determine the effects of low-pressure intra-abdominal application on laparoscopic cholecystectomy on acid-base equilibrium. Thirty patients were included in this study. Group 1 patients had 8 mmHg intra-abdominal pressure and Group 2 had 12 mmHg intra-abdominal pressure when they were operated on. There were no significant differences between the groups in terms of their age, sex, body mass index, insufflation and operation time, and anesthesia duration. The acid-base equilibrium situations were similar. Short-term metabolic, respiratory, and mix-type acidosis was observed during the operation and becomes normal in the recovery room. Acidosis is more likely related to the absorption of CO2 in the peritoneum rather than to secondary changes caused by intra-abdominal pressure increases. No positive effects of the application of intra-abdominal low pressure on laparoscopic cholecystectomy on acid-base equilibrium were observed in our study.
authors.affiliation: Department of General Surgery, Baskent University, Ankara, Turkey. erdalk@mail.baskent-kon.edu.tr
authors.forename: Erdal
authors.initials: E
authors.lastname: Karagulle
authors.forename: Emin
authors.initials: E
authors.lastname: Turk
authors.forename: Rafi
authors.initials: R
authors.lastname: Dogan
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Ekici
authors.forename: Durmus
authors.initials: D
authors.lastname: Sahin
authors.forename: Gokhan
authors.initials: G
authors.lastname: Moray
mesh_terms: D000137:Acid-Base Imbalance / Q000209:etiology*; D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000378:metabolism; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D002769:Cholelithiasis / Q000601:surgery*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007327:Insufflation / Q000009:adverse effects; D007773:Lactates / Q000097:blood; D008297:Male; D008875:Middle Aged; D011028:Pneumoperitoneum, Artificial / Q000009:adverse effects*; D011312:Pressure; D018709:Statistics, Nonparametric
chemical_list: D007773:Lactates; D002245:Carbon Dioxide