title: Phenolic compounds and bioactivity of leaves of Mayodendron igneum Kurz.
abstract: Four apigenin glycosides were isolated from the ethyl acetate extract of the leaves of Mayodendron igneum Fam.Bignoniaceae. They were identified as apigenin 7-O-glucoside; 6-methoxy apigenin-7-O-glucoside; 6-methoxy apigenin-7-O-rhamnoglucoside and 6-hydroxy apigenin-7-O-rhamnoglucoside. In addition an isoflavone glycoside was isolated, and identified as genistin 5,4'-methyl ether. Ethanol (80%) extract of Mayodendron igneum leaves exhibited significant anti-inflammatory and analgesic activities. LD(50) determination of the extract indicated the safety of the leaves of the plant.
authors.affiliation: Pharmacognosy Department, National Research Centre, Dokki, Cairo, Egypt.
authors.forename: F A
authors.initials: FA
authors.lastname: Hashem
authors.forename: S A
authors.initials: SA
authors.lastname: el-Sawi
authors.forename: A A
authors.initials: AA
authors.lastname: Sleem