title: Neurotoxic manifestations of an overdose intrathecal injection of gadopentetate dimeglumine.
abstract: The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global aphasia, rigidity, and visual disturbance.
authors.affiliation: Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
authors.forename: Kwan-Woong
authors.initials: KW
authors.lastname: Park
authors.forename: Soo-Bin
authors.initials: SB
authors.lastname: Im
authors.forename: Bum-Tae
authors.initials: BT
authors.lastname: Kim
authors.forename: Sun-Chul
authors.initials: SC
authors.lastname: Hwang
authors.forename: Jong-Sun
authors.initials: JS
authors.lastname: Park
authors.forename: Won-Han
authors.initials: WH
authors.lastname: Shin
mesh_terms: D000328:Adult; D001037:Aphasia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000187:drug effects / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage / Q000633:toxicity; D019786:Gadolinium DTPA / Q000008:administration & dosage / Q000633:toxicity; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D009127:Muscle Rigidity / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D020258:Neurotoxicity Syndromes / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000209:etiology / Q000473:pathology
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA