title: Hypophosphataemic osteomalacia in neurofibromatosis.
abstract: Oncogenic Osteomalacia syndrome is associated with mesenchymal tumours, caused by a protein secreted from tumours which inhibits tubular renal phosphate absorption and reduces 1,25 dihydroxy vitamin-D renal conversion. It manifests as osteomalacia with hypophosphataemia and hyperphosphaturia. Association of neurofibromatosis with oncogenic osteomalacia is unusual. We report a rare case of oncogenic osteomalacia with generalized neurofibromatosis which presented to us as pathological fracture.
authors.affiliation: Department of Orthopaedics, University College of Medical Sciences & Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Chadha
authors.forename: Ajay Pal
authors.initials: AP
authors.lastname: Singh
authors.forename: Arun Pal
authors.initials: AP
authors.lastname: Singh
mesh_terms: D005260:Female; D005264:Femoral Fractures / Q000209:etiology; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D017674:Hypophosphatemia / Q000150:complications*; D008875:Middle Aged; D017253:Neurofibromatoses / Q000150:complications*; D010018:Osteomalacia / Q000150:complications*