Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent.
meso-Octamethyloctafluorocalixpyrrole, a simple tetrapyrrolic macrocycle, has been shown to function as both a chloride/nitrate and a chloride/bicarbonate antiport agent for lipid bilayer transmembrane anion transport. This is the first example of a synthetic macrocyclic pyrrole-based receptor capable of transmembrane bicarbonate transport.
Gale
Philip A
PA
School of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom. philip.gale@soton.ac.uk
Tong
Christine C
CC
Haynes
Cally J E
CJ
Adeosun
Olubukunola
O
Gross
Dustin E
DE
Karnas
Elizabeth
E
Sedenberg
Elaine M
EM
Quesada
Roberto
R
Sessler
Jonathan L
JL
D000838:Anions / Q000737:chemistry; D001639:Bicarbonates / Q000737:chemistry; D047250:Calixarenes / Q000737:chemistry* / Q000494:pharmacology; D027963:Chloride-Bicarbonate Antiporters / Q000737:chemistry* / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry; D009566:Nitrates / Q000737:chemistry; D010713:Phosphatidylcholines / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry* / Q000494:pharmacology; D012965:Sodium Chloride / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry
D000838:Anions; D001639:Bicarbonates; D027963:Chloride-Bicarbonate Antiporters; D008051:Lipid Bilayers; D009566:Nitrates; D010713:Phosphatidylcholines; D011166:Porphyrins; D013431:Sulfates; C469811:calix(4)pyrrole; C550129:octafluorocalix(4)pyrrole; C012036:sodium sulfate; D047250:Calixarenes; D012965:Sodium Chloride; C028694:1-palmitoyl-2-oleoylphosphatidylcholine