title: A probable association of acute dystonia with gemifloxacin administration.
abstract: Gemifloxacin is a recently introduced fluoroquinolone antibiotic frequently used for its broad spectrum and once-daily dosing. Fluoroquinolones are associated with various neuropsychiatric side effects, such as seizures, insomnia, confusion, lightheadedness, psychosis, paranoia and hallucinations. We report a case of a 36-year-old woman given gemifloxacin for an upper respiratory tract infection who developed acute dystonia on the third day following therapy initiation. The clinical implications are discussed.
authors.affiliation: Department of Psychiatry, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
authors.forename: Dinesh Dutt
authors.initials: DD
authors.lastname: Sharma
authors.forename: Ashish
authors.initials: A
authors.lastname: Aggarwal
authors.forename: Ravi C
authors.initials: RC
authors.lastname: Sharma
authors.forename: Ramesh
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced* / Q000523:psychology; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects*; D000077735:Gemifloxacin; D006801:Humans; D009287:Naphthyridines / Q000009:adverse effects*; D012141:Respiratory Tract Infections
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; D000077735:Gemifloxacin