title: PRISMA: a pan-European co-ordinating action to advance the science in end-of-life cancer care.
abstract: BACKGROUND
  The epidemiology of progressive cancer and associated mortality in Europe underlines the essential need for high quality palliative and end-of-life care for its citizens. Currently, care of patients at the end-of-life is under-researched and under-funded. This is due to a lack of prioritisation, challenges in defining end-of-life, lack of a common research strategy for Europe that identifies and implements best practice and highest scientific principles, and the need for common use of appropriate well-validated tools to measure and improve the end-of-life cancer experience in Europe.
  
  
  METHODS
  PRISMA is a pan-European co-ordinating action funded under Framework Programme 7 of the European Commission. With 12 partners in 9 countries, it is delivering a series of 8 Work Packages with the common aim of promoting best practice in the measurement of end-of-life care, setting an agenda and guidance that reflects European cultural diversity, and is informed by both public and clinical priorities. Guidance in the selection, adaptation and use of core tools is informed by experts in public health and clinical research.
  
  
  CONCLUSIONS
  PRISMA is currently producing a series of outputs to be accessible to the wider community of researchers, policy makers, funders and clinicians. We encourage new partnerships to build on the work of PRISMA and to lead high quality work informed by our deliverables. PRISMA, we hope, is redressing the current lack of co-ordination of cancer end-of-life research across Europe, and will catalyse the conduct of evidence-based care that reflects European populations and priorities.
authors.affiliation: King's College London, Department of Palliative Care, Policy and Rehabilitation, School of Medicine at Guy's King's and St. Thomas Hospitals, Cicely Saunders Institute, Bessemer Road, London SE5 9PJ, UK. richard.harding@kcl.ac.uk
authors.forename: Richard
authors.initials: R
authors.lastname: Harding
authors.forename: Irene J
authors.initials: IJ
authors.lastname: Higginson
mesh_terms: D035843:Biomedical Research; D003469:Culture; D005060:Europe; D006292:Health Priorities; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D009735:Nursing Homes; D017063:Outcome Assessment, Health Care; D017060:Patient Satisfaction; D011364:Professional Practice; D013727:Terminal Care / Q000458:organization & administration*