title: The worst case: giant exulcerating seminoma.
abstract: Ten years after his brother had been treated for seminoma, a 36-year-old male presented with a giant exulcerating mass involving the right testis and both inguinal regions. Subsequent biopsy revealed pure seminoma. Staging computed tomography (CT) showed bulky retroperitoneal and pelvic lymph node metastases. After seven courses of cisplatin-based chemotherapy, positron emission tomography suggested residual tumor in the right groin. The suspicious lesion and the right testis were resected showing no vital tumor tissue. Eight months after surgery there were no signs of disease progression at follow-up CT.
authors.affiliation: Department of Urology and Pediatric Urology, Julius Maximilians University Medical School, Oberdürrbacher Strasse 6, DE-97080 Würzburg, Germany. Letsch_M@klinik.uni-wuerzburg.de
authors.forename: Markus
authors.initials: M
authors.lastname: Letsch
authors.forename: Martin
authors.initials: M
authors.lastname: Spahn
authors.forename: Matthias
authors.initials: M
authors.lastname: Beissert
authors.forename: Max S
authors.initials: MS
authors.lastname: Topp
authors.forename: Elmar W
authors.initials: EW
authors.lastname: Gerharz
authors.forename: Hubertus
authors.initials: H
authors.lastname: Riedmiller
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D018450:Disease Progression; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods; D018239:Seminoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D013737:Testis / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin