title: Impulsive smoking in a patient with Parkinson's disease treated with dopamine agonists.
abstract: Impulse control disorders, including pathological gambling, binge eating, compulsive shopping and hypersexual behaviors, have frequently been reported as a side effect of dopaminergic medications for Parkinson's disease (PD). Here we describe a patient with PD who developed an unusual manifestation of impulsive behaviors, including cigarette smoking, associated with an increase in dopamine agonist medication. We postulate this to be related to an overstimulation of mesolimbic dopamine receptors responsible for reward-seeking behaviors. Further research is needed to examine impulsive cigarette smoking in PD.
authors.affiliation: Department of Psychiatry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA.
authors.forename: Karina L
authors.initials: KL
authors.lastname: Bienfait
authors.forename: Matthew
authors.initials: M
authors.lastname: Menza
authors.forename: Margery H
authors.initials: MH
authors.lastname: Mark
authors.forename: Roseanne D
authors.initials: RD
authors.lastname: Dobkin
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects; D052160:Benzothiazoles / Q000009:adverse effects; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000139:chemically induced*; D018491:Dopamine Agonists / Q000009:adverse effects*; D006801:Humans; D007175:Impulsive Behavior / Q000139:chemically induced; D007211:Indoles / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D000077487:Pramipexole; D012563:Schizophrenia, Paranoid / Q000139:chemically induced; D012907:Smoking
chemical_list: D000978:Antiparkinson Agents; D052160:Benzothiazoles; D018491:Dopamine Agonists; D007211:Indoles; C046649:ropinirole; D000077487:Pramipexole