title: Vibrational circular dichroism of 3-(trifluoroacetyl)-camphor and its interaction with chiral amines.
abstract: Vibrational circular dichroism (VCD) spectroscopy and density functional theory (DFT) calculations are used to investigate the keto-enol equilibrium of 3-(trifluoroacetyl)-camphor (TFC) and to study the interaction of TFC with chiral amines in deuterated Chloroform. It is shown that the VCD spectra of the enol- and keto forms of TFC can clearly be distinguished and that the enol form is favored. By deprotonation of the TFC enol with chiral amines, no indication of a mutual diasteriomeric influence on the VCD spectra induced by transfer of stereochemical information between the chiral ionic species is found, neither experimentally nor theoretically.
authors.affiliation: Fraunhofer Institute of Manufacturing Technology and Applied Materials Research (IFAM), Department of Adhesive Bonding Technology and Surfaces, 28359 Bremen, Germany. christian.merten@ifam.fraunhofer.de
authors.forename: Christian
authors.initials: C
authors.lastname: Merten
authors.forename: Karl J
authors.initials: KJ
authors.lastname: Jalkanen
authors.forename: Volker C
authors.initials: VC
authors.lastname: Weiss
authors.forename: Andreas
authors.initials: A
authors.lastname: Hartwig