title: Correlation between disc damage likelihood scale and optical coherence tomography in the diagnosis of glaucoma.
abstract: OBJECTIVE
  To investigate the relationship between the Disc Damage Likelihood Scale (DDLS), visual field and various optical coherence tomography (OCT) parameters for glaucoma diagnosis.
  
  
  METHODS
  The study comprised 149 eyes from 149 patients. The patients were categorized as normal, glaucoma suspect or with glaucoma. They were clinically examined and graded according to the DDLS system. OCT was performed to acquire both a retinal nerve fibre layer analysis and an optic nerve head analysis. The relationships between DDLS score, visual field and OCT parameters were analysed using multiple correlation analysis.
  
  
  RESULTS
  The normal, glaucoma suspect and glaucoma groups had average DDLS scores of 1.58 +/- 1.40, 2.55 +/- 1.93 and 5.33 +/- 1.39, respectively. Evaluating the area under the receiver operator characteristic curve, the DDLS had the best predictive power (0.917), followed by corrected pattern standard deviation.
  
  
  CONCLUSIONS
  The DDLS is a useful parameter in the diagnosis of glaucoma and it showed a close correlation with visual field, cup/disc ratio and OCT parameters.
authors.affiliation: Department of Ophthalmology, Oxford Eye Hospital, University of Oxford, Oxford, UK.
authors.forename: Aman Shah B
authors.initials: AS
authors.lastname: Abdul Majid
authors.forename: Jee Hyun
authors.initials: JH
authors.lastname: Kwag
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Jung
authors.forename: Hye Bin
authors.initials: HB
authors.lastname: Yim
authors.forename: Yeon Deok
authors.initials: YD
authors.lastname: Kim
authors.forename: Kui Dong
authors.initials: KD
authors.lastname: Kang
mesh_terms: D000328:Adult; D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009798:Ocular Hypertension / Q000175:diagnosis; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012372:ROC Curve; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000175:diagnosis; D058609:Visual Field Tests; D014794:Visual Fields