title: Recurrent ptosis due to myopathy of the levator palpebrae superioris.
abstract: The authors report the 10-year follow-up of a case with a recurrent ptosis affecting both eyelids independently. The histology of the levator palpebrae superioris and Müller's muscle was consistent with a localised myopathic process. A therapeutic response to acetazolamide suggests that ion-channel dysfunction may be the underlying cause for this new myopathy.
authors.affiliation: UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. a.petzold@ion.ucl.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Petzold
authors.forename: P J
authors.initials: PJ
authors.lastname: Luthert
authors.forename: J R O
authors.initials: JR
authors.lastname: Collin
authors.forename: G T
authors.initials: GT
authors.lastname: Plant
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D001763:Blepharoptosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D005141:Eyelid Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009135:Muscular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide