Trabecular bone strains around a dental implant and associated micromotions--a micro-CT-based three-dimensional finite element study.
The first objective of this computational study was to assess the strain magnitude and distribution within the three-dimensional (3D) trabecular bone structure around an osseointegrated dental implant loaded axially. The second objective was to investigate the relative micromotions between the implant and the surrounding bone. The work hypothesis adopted was that these virtual measurements would be a useful indicator of bone adaptation (resorption, homeostasis, formation). In order to reach these objectives, a microCT-based finite element model of an oral implant implanted into a Berkshire pig mandible was developed along with a robust software methodology. The finite element mesh of the 3D trabecular bone architecture was generated from the segmentation of microCT scans. The implant was meshed independently from its CAD file obtained from the manufacturer. The meshes of the implant and the bone sample were registered together in an integrated software environment. A series of non-linear contact finite element (FE) analyses considering an axial load applied to the top of the implant in combination with three sets of mechanical properties for the trabecular bone tissue was devised. Complex strain distribution patterns are reported and discussed. It was found that considering the Young's modulus of the trabecular bone tissue to be 5, 10 and 15GPa resulted in maximum peri-implant bone microstrains of about 3000, 2100 and 1400. These results indicate that, for the three sets of mechanical properties considered, the magnitude of maximum strain lies within an homeostatic range known to be sufficient to maintain/form bone. The corresponding micro-motions of the implant with respect to the bone microstructure were shown to be sufficiently low to prevent fibrous tissue formation and to favour long-term osseointegration.
Limbert
Georges
G
Biomaterials & Biomechanics Research Centre, School of Dentistry, Wales College of Medicine, Cardiff University, Cardiff CF14 4XY, UK. g.limbert@soton.ac.uk
van Lierde
Carl
C
Muraru
O Luiza
OL
Walboomers
X Frank
XF
Frank
Milan
M
Hansson
Stig
S
Middleton
John
J
Jaecques
Siegfried
S
D000818:Animals; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000378:metabolism; D019250:Dental Implants, Single-Tooth; D020342:Finite Element Analysis; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008334:Mandible / Q000000981:diagnostic imaging / Q000502:physiology*; D008954:Models, Biological; D010012:Osteogenesis / Q000502:physiology; D012984:Software; D013552:Swine; D055114:X-Ray Microtomography