title: Ectopic ossification with haematopoietic bone marrow in the heart valves of a crossbred heavy horse.
abstract: Ectopic bone formation in the left atrioventricular valves and cardiac fibroskeleton, with systemic circulatory disturbance, is reported in a 4-year-old crossbred heavy horse. Microscopically, there was fibrosis, chondral metaplasia and mature bone, with bone marrow within the left atrioventricular cusps and in the annuli of the aortic and right atrioventricular valves.
authors.affiliation: Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan. kmatsuda@rakuno.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Matsuda
authors.forename: S
authors.initials: S
authors.lastname: Tabata
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Kurosawa
authors.forename: N
authors.initials: N
authors.lastname: Yoshie
authors.forename: H
authors.initials: H
authors.lastname: Taniyama
mesh_terms: D000818:Animals; D017849:Animals, Inbred Strains; D001842:Bone and Bones / Q000473:pathology; D005260:Female; D005355:Fibrosis; D006325:Heart Atria / Q000473:pathology; D006349:Heart Valve Diseases / Q000473:pathology / Q000662:veterinary*; D006351:Heart Valves / Q000473:pathology*; D006352:Heart Ventricles / Q000473:pathology; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D006824:Hybridization, Genetic; D008679:Metaplasia / Q000473:pathology; D009999:Ossification, Heterotopic / Q000473:pathology*