title: Quantitative and morphometric changes of subpopulations of myenteric neurons in swines with toxoplasmosis.
abstract: The consequences of the infection caused by Toxoplasma gondii in myenteric neurons of the jejunum of swines reactive to NADH-diaphorase and NADPH-diaphorase were evaluated in this study. Ten 88-day-old mixed-breed swines (Pietrain and Wessex) were assigned into two groups: Control (n=5) and Experimental (n=5), which orally received 5000 sporulated oocysts from a genotype III T. gondii strain. After 30days, the animals were anesthetized, having part of their jejunum removed and stained with NADPH-diaphorase and NADH-diaphorase. NADPHd-p neurons (nitrergic) presented increase of the number of cells per ganglion and hypertrophy. The number of NADHd-p neurons (metabolic more active) and their nuclear area decreased.
authors.affiliation: Programa de Pós-Graduação em Ciência Animal, Universidade Paranaense, PR, Brazil.
authors.forename: Leandro
authors.initials: L
authors.lastname: Odorizzi
authors.forename: Neide Martins
authors.initials: NM
authors.lastname: Moreira
authors.forename: Gentil Ferreira
authors.initials: GF
authors.lastname: Gonçalves
authors.forename: Aristeu Vieira
authors.initials: AV
authors.lastname: da Silva
authors.forename: Débora de Mello Gonçales
authors.initials: Dde M
authors.lastname: Sant'ana
authors.forename: Eduardo José de Almeida
authors.initials: EJ
authors.lastname: Araújo
mesh_terms: D000818:Animals; D008058:Dihydrolipoamide Dehydrogenase / Q000096:biosynthesis; D015870:Gene Expression; D009197:Myenteric Plexus / Q000201:enzymology / Q000473:pathology*; D009252:NADPH Dehydrogenase / Q000096:biosynthesis; D009474:Neurons / Q000201:enzymology / Q000473:pathology*; D013552:Swine; D014124:Toxoplasmosis, Animal / Q000201:enzymology / Q000473:pathology*
chemical_list: D009252:NADPH Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase