Toxic epidermal necrolysis-like cutaneous lupus erythematosus: A series of three patients.
Toxic epidermal necrolysis-like lesions have been described in the setting of lupus erythematosus, and have been considered as a specific hyperacute variant of cutaneous lupus erythematosus, with features different from classical drug-related toxic epidermal necrolysis. We report here a series of three patients with lupus erythematosus who presented with severe worsening of their cutaneous disease in a toxic epidermal necrolysis-like fashion. We compared these cases with cases reported previously. Based on this discussion, we speculate that some of these patients may have classical drug-related toxic epidermal necrolysis rather than lupus erythematosus-related toxic epidermal necrolysis.
Cisneros
Claudia G C
CG
Department of Dermatology, University of Sao Paulo, Brazil. gercisneros90@yahoo.com
Romiti
Ricardo
R
Santi
Cláudia G
CG
Aoki
Valéria
V
Valente
Neusa Y S
NY
Nico
Marcello M S
MM
D000293:Adolescent; D001379:Azathioprine / Q000627:therapeutic use; D002738:Chloroquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D012720:Severity of Illness Index; D012867:Skin / Q000187:drug effects / Q000473:pathology*; D013262:Stevens-Johnson Syndrome / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult
D007166:Immunosuppressive Agents; C023676:chloroquine diphosphate; D002738:Chloroquine; D011239:Prednisolone; D001379:Azathioprine