Towards dynamic control of magnetic fields to focus magnetic carriers to targets deep inside the body.
Magnetic drug delivery has the potential to target therapy to specific regions in the body, improving efficacy and reducing side effects for treatment of cancer, stroke, infection, and other diseases. Using stationary external magnets, which attract the magnetic drug carriers, this treatment is limited to shallow targets (<5 cm below skin depth using the strongest possible, still safe, practical magnetic fields). We consider dynamic magnetic actuation and present initial results that show it is possible to vary magnets one against the other to focus carriers between them on average. The many remaining tasks for deep targeting in-vivo are then briefly noted.
Shapiro
Benjamin
B
Bio-Engineering/Aerospace Engineering, 3178 Martin Hall, University of Maryland at College Park, College Park, MD 20742, USA.