title: Synthesis of AZT-based cationic lipids and in vitro evaluation of siRNA delivery.
abstract: New types of cationic lipids based on AZT were evaluated for their biological effects in terms of their cytotoxicity and their cellular delivery of siRNA.
authors.affiliation: Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, South Korea.
authors.forename: Sun Min
authors.initials: SM
authors.lastname: Park
authors.forename: Jungeun
authors.initials: J
authors.lastname: Woo
authors.forename: Eunmi
authors.initials: E
authors.lastname: Jeon
authors.forename: Byeang Hyean
authors.initials: BH
authors.lastname: Kim
mesh_terms: D002412:Cations / Q000737:chemistry*; D004337:Drug Carriers; D004797:Enzyme-Linked Immunosorbent Assay; D006367:HeLa Cells; D006801:Humans; D052578:Ionic Liquids / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000008:administration & dosage* / Q000378:metabolism; D042461:Vascular Endothelial Growth Factor A / Q000235:genetics; D015215:Zidovudine / Q000737:chemistry*
chemical_list: D002412:Cations; D004337:Drug Carriers; D052578:Ionic Liquids; D034741:RNA, Small Interfering; D042461:Vascular Endothelial Growth Factor A; D015215:Zidovudine