Two new terpene glucosides and antitumor agents from Centipeda minima.
One new monoterpene glucoside minimaoside A (1) and one new sesquiterpene glucoside minimaoside B (2), together with four known terpenoids, were isolated from the whole plants of Centipeda minima (L.) A. Braun et Ashers. Their structures were determined by spectroscopic methods. Compounds 5 and 6 showed weak or moderate cytotoxic activity toward several tumor cell lines.
Ding
Lin-Fen
LF
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Liu
Ying
Y
Liang
Heng-Xing
HX
Liu
Da-Peng
DP
Zhou
Guang-Biao
GB
Cheng
Yong-Xian
YX
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D012717:Sesquiterpenes; D013729:Terpenes; C547791:minimaoside A; C547792:minimaoside B