Spectrally encoded confocal scanning laser ophthalmoscopy.
We present in vivo human fundus imaging using a fiber-based confocal scanning laser ophthalmoscope (SLO). Spectrally encoded confocal scanning laser ophthalmoscopy (SECSLO) utilizes a spectral encoding technique in one dimension, combined with single-axis lateral scanning, to create video-rate reflectivity maps of the fundus. This implementation of the SLO allows for high-contrast high-resolution in vivo human retinal imaging through a single-mode optical fiber. We experimentally quantify the full confocality of SECSLO in both the spectrally encoded and laterally scanned dimensions, and demonstrate 50 Hz frame rate fundus imaging.
Tao
Yuankai K
YK
Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA. yt13@duke.edu
Izatt
Joseph A
JA
D002404:Catheterization; D004724:Endoscopy; D005654:Fundus Oculi; D006801:Humans; D007834:Lasers; D057054:Molecular Imaging; D009887:Ophthalmoscopy / Q000379:methods*