A highly selective fluorescent probe for Hg(2+) based on a rhodamine-coumarin conjugate.
A fluorescent probe 1 for Hg(2+) based on a rhodamine-coumarin conjugate was designed and synthesized. Probe 1 exhibits high sensitivity and selectivity for sensing Hg(2+), and about a 24-fold increase in fluorescence emission intensity is observed upon binding excess Hg(2+) in 50% water/ethanol buffered at pH 7.24. The fluorescence response to Hg(2+) is attributed to the 1:1 complex formation between probe 1 and Hg(2+), which has been utilized as the basis for the selective detection of Hg(2+). Besides, probe 1 was also found to show a reversible dual chromo- and fluorogenic response toward Hg(2+) likely due to the chelation-induced ring opening of rhodamine spirolactam. The analytical performance characteristics of the proposed Hg(2+)-sensitive probe were investigated. The linear response range covers a concentration range of Hg(2+) from 8.0x10(-8) to 1.0x10(-5)molL(-1) and the detection limit is 4.0x10(-8)molL(-1). The determination of Hg(2+) in both tap and river water samples displays satisfactory results.
Ma
Qiu-Juan
QJ
College of Pharmacology, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, PR China.
Zhang
Xiao-Bing
XB
Zhao
Xu-Hua
XH
Jin
Zhen
Z
Mao
Guo-Jiang
GJ
Shen
Guo-Li
GL
Yu
Ru-Qin
RQ
D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D003374:Coumarins; D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D012235:Rhodamines; D014874:Water Pollutants, Chemical; C030123:coumarin; D008628:Mercury