Cutaneous manifestations of Mycobacterium gordonae infection described for the first time in Italy: a case report.
BACKGROUND
Mycobacterium gordonae is one of the least pathogenic of the mycobacteria. This pathogen may produce caseating or non-caseating granulomas, and skin lesions showing acute or chronic inflammation with scattered histiocytes and giant cells have been seen. The mortality rate is less than 0.1%. Mycobacterium gordonae may be a marker of severe immunosuppression in patients infected with human immunodeficiency virus.


METHODS
We report a case of Mycobacterium gordonae infection in an 86-year-old woman and discuss the problems inherent to the identification and treatment of this emerging pathogen. Mycobacterium gordonae strain we isolated was resistant to trimethoprim-sulfamethoxazole but sensitive to ciprofloxacin, and long term administration (six months) induced complete healing of the cutaneous abscesses.


CONCLUSIONS
Advanced laboratory diagnostic techniques have improved the isolation and identification of nontuberculous mycobacteria. The diagnosis requires a high index of clinical suspicion, as detection by conventional methods is difficult. To our knowledge, this patient is the first documented case of cutaneous infection from this pathogen in Italy.
Foti
Caterina
C
Department of Internal Medicine, Immunology and Infectious Diseases, Unit of Dermatology, University of Bari, Bari, Italy. c.foti@dermatologia.uniba.it
Sforza
Vincenza
V
Rizzo
Caterina
C
De Pascale
Giovanna
G
Bonamonte
Domenico
D
Conserva
Anna
A
Tarantino
Antonio
A
Stella
Camilla
C
Cantore
Stefania
S
Grassi
Roberto Felice
RF
Ballini
Andrea
A
De Vito
Danila
D
Angelini
Giovanni
G