Central corneal thickness, anterior chamber depth, and pupil diameter measurements using Visante OCT, Orbscan, and Pentacam.
OBJECTIVE
To evaluate the agreement among three different optical methods in measuring anterior chamber depth (ACD), central corneal thickness (CCT), and pupil diameter.


METHODS
One hundred eyes of 50 healthy patients (25 men, 25 women) were enrolled in the study. Mean patient age was 25 years (range: 21 to 32 years). Exclusion criteria were history of any intraocular or corneal surgery, contact lens wear, corneal anomalies, and spherical refraction >5.00 diopters (D) or cylindrical refraction >2.00 D. All measurements were done by the same operator under mesopic light conditions and repeated using three different optical methods: Visante optical coherence tomography (OCT) (Carl Zeiss Meditec), Orbscan (Bausch & Lomb), and Pentacam (Oculus Optikgeräte GmbH).


RESULTS
Mean CCT as measured by Visante OCT, Orbscan, and Pentacam was 529+/-30.5 microm, 554+/-32.7 microm, and 552+/-29.3 microm, respectively. Mean ACD values were 2.94+/-0.34 mm, 2.84+/-0.33 mm, and 2.98+/-0.33 mm, respectively. Mean pupil diameter measurements were 4.87+/-1.09 mm, 4.0+/-0.67 mm, and 3.05+/-0.59 mm, respectively. The Visante OCT measured CCT thinner and Orbscan measured ACD shallower than the other two methods. All three methods measured pupil diameters significantly different.


CONCLUSIONS
This study found some statistically significant but clinically insignificant differences among the optical methods assessed. The differences are small and do not influence decisions for refractive surgery in clinical practice.
Yazici
Ahmet Taylan
AT
Beyoglu Eye Research and Training Hospital, Istanbul, Turkey.
Bozkurt
Ercument
E
Alagoz
Cengiz
C
Alagoz
Nese
N
Pekel
Gokhan
G
Kaya
Vedat
V
Yilmaz
Omer Faruk
OF
D000328:Adult; D000867:Anterior Chamber / Q000033:anatomy & histology*; D000886:Anthropometry; D001699:Biometry; D003315:Cornea / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007368:Interferometry / Q000379:methods*; D008027:Light; D008297:Male; D010781:Photography / Q000379:methods*; D011680:Pupil; D012016:Reference Values; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult