title: Simulated dose reduction by adding artificial noise to measured raw data: a validation study.
abstract: The purpose of this study was to verify and validate a noise simulation tool called Dose Tutor (VAMP GmbH) in terms of level and texture of the simulated noise. By adding artificial noise to measured computed tomography (CT) raw data, a scan acquired with a lower dose (mAs) than the actual one can be simulated. A homogeneous polyethylene phantom and an anthropomorphic chest phantom were scanned for different mAs levels, tube voltages, slice thicknesses and reconstruction kernels. The simulated noise levels were compared with the noise levels in real transverse slice images actually acquired with corresponding mAs values. In general, the noise comparisons showed acceptable agreement in magnitude (<20 % deviation in pixel standard deviation). Also, the calculated noise power spectra were similar, which indicates that the noise texture is correctly reproduced. In conclusion, this study establishes that the Dose Tutor might be a useful tool for estimating the dose reduction potential for CT protocols.
authors.affiliation: Department of Medical Radiation Physics, Malmö, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden. marcus.soderberg@med.lu.se
authors.forename: Marcus
authors.initials: M
authors.lastname: Söderberg
authors.forename: Mikael
authors.initials: M
authors.lastname: Gunnarsson
authors.forename: Mats
authors.initials: M
authors.lastname: Nilsson
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001822:Body Burden; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*