Comparison and prediction of the retention in micellar electrokinetic chromatography and microemulsion electrokinetic chromatography for disubstituted benzenes.
Retention index (I), rather than retention factor (k), was found to be a more reasonable parameter for comparison of the relative affinity of disubstituted benzenes in MEEKC and MEKC, due to independent of I with the SDS surfactant concentration. MEKC and MEEKC may give similar or different I values, depending on types of moieties. With known I and K(ow) for alkylbenzenes as references in MEKC and MEEKC, the values of K(ow) for disubstituted benzenes can be estimated from the observed I values, where K(ow) is the octanol-water distribution constant. In addition, a group additive approach can be used to predict I for disubstituted benzenes with different moieties from the average observed I for the disubstituted benzenes with same moieties. However, electronic effects and/or intramolecular interaction may result in the different observed I from prediction.
Angkanasiriporn
Siriporn
S
Chromatography and Separation Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Singsung
Wuttipong
W
Petsom
Amorn
A
Nhujak
Thumnoon
T
D001555:Benzene Derivatives / Q000737:chemistry*; D001559:Benzhydryl Compounds; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D003474:Curcumin / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry; D016014:Linear Models; D000442:Octanols / Q000737:chemistry; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry; D014867:Water / Q000737:chemistry; D000098826:Bisphenol A Compounds
D001555:Benzene Derivatives; D001559:Benzhydryl Compounds; D003474:Curcumin; D004852:Epoxy Compounds; D000442:Octanols; D012967:Sodium Dodecyl Sulfate; D014867:Water; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds