title: Early weaning and other potential risk factors for overweight among preschool children.
abstract: OBJECTIVE
  To investigate whether early weaning constitutes a risk factor for overweight at preschool age and to identify other factors that affect this association.
  
  
  METHODS
  This was a case-control study of 366 children aged 2 to 6 years (176 boys and 190 girls) from three cities. The case group comprised overweight children, as defined by body mass index (BMI) for age greater than or equal to the 85(th) percentile. The main exposure analyzed was early weaning (exclusive or predominant breastfeeding for less than four months).
  
  
  RESULTS
  Early weaning was a significant risk factor for overweight in univariate analysis (OR = 1.69; 95% CI: 1.10-2.60; p = 0.02), but not in multivariate analysis (OR = 1.42; 95% CI: 0.86-2.34; p = 0.17). Maternal overweight, birth weight > or = 3,500 g and sedentarism were the main risk factors for overweight in multivariate analysis.
  
  
  CONCLUSIONS
  In our study, the protective effect of breastfeeding against overweight was only shown in univariate analysis; it did not persist after controlling for other variables. It is possible that breastfeeding has only a small protective role against overweight in comparison with other variables of greater importance.
  
  
  CONCLUSIONS
  Our results suggest that the potential protective effect of breastfeeding against overweight among preschool children is weaker than genetic and other environmental factors.
authors.affiliation: Federal University of Ceará and School of Medicine of Juazeiro do Norte - Ceará/PE, Brazil. genibalaban@hotmail.com
authors.forename: Geni
authors.initials: G
authors.lastname: Balaban
authors.forename: Maria Eugênia Farias Almeida
authors.initials: ME
authors.lastname: Motta
authors.forename: Giselia Alves Pontes
authors.initials: GA
authors.lastname: Silva
mesh_terms: D015992:Body Mass Index; D001942:Breast Feeding / Q000706:statistics & numerical data*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D050177:Overweight / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors; D057185:Sedentary Behavior; D012959:Socioeconomic Factors; D013997:Time Factors; D014886:Weaning