Plasma concentration of anti-diuretic hormone and urine volume in response to intraruminal administration of acetate, propinata and butyrate in suckling calves.
Acetate, propionate, and butyrate were intraruminally administered to dry feed-fed suckling calves to evaluate their effects on plasma ketone bodies, anti-diuretic hormone (ADH) concentrations, and urine volume. Four male Holstein calves (5-7 weeks old) were given 1.0 L of warm water or 0.5 mole of one of the acids in 1.0 L of warm water. A 4 x 4 Latin square design was adopted for the experiment. The acetate group showed significantly higher plasma acetate concentrations than the other three groups between 0.25 h and 2.0 h after administration (P < 0.01). Plasma glucose concentrations did not differ markedly among the groups. The butyrate group showed significantly higher plasma ketone body concentrations than the other three groups until the end of the experiment (P < 0.01). Plasma ADH concentrations quickly rose in the butyrate group and remained significantly higher than in the other three groups from 0.25 h to 2.5 h after administration (P < 0.05). In accordance with the elevation of plasma ADH levels, the butyrate group showed decreases in urine volume and increases in urine osmolarity (P < 0.05). Plasma osmolarity and hematocrit values (Ht) were not different among the groups. These results suggest that the administration of acetate and propionate had little effect on ADH secretion.
Iriki
Tsunenori
T
Laboratory of Nutrition, Azabu University School of Veterinary Medicine, Sagamihara, Japan. iriki@azabu-u.ac.jp
Nakamura
Tomomi
T
Obigata
Rui
R
Onda
Ken
K
D000085:Acetates / Q000008:administration & dosage*; D000818:Animals; D002087:Butyrates / Q000008:administration & dosage*; D002417:Cattle / Q000502:physiology*; D007657:Ketone Bodies / Q000097:blood; D008297:Male; D009994:Osmolar Concentration; D011422:Propionates / Q000008:administration & dosage*; D012417:Rumen; D014556:Urine; D014667:Vasopressins / Q000097:blood*
D000085:Acetates; D002087:Butyrates; D007657:Ketone Bodies; D011422:Propionates; D014667:Vasopressins