Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions.
A simple synthetic strategy has been developed for accessing internally functionalized dendrimers. The key feature of this approach is the use of two orthogonal and efficient reactions--'epoxy-amine' and 'thiol-ene' coupling--for rapid growth of the dendritic scaffold. This sequence of reactions allows for the introduction of reactive hydroxyl groups at each dendritic layer.
Kang
Taegon
T
Materials Research Laboratory, University of California, Santa Barbara, CA 93106-5121, USA.
Amir
Roey J
RJ
Khan
Anzar
A
Ohshimizu
Kaoru
K
Hunt
Jasmine N
JN
Sivanandan
Kulandaivelu
K
Montañez
Maria I
MI
Malkoch
Michael
M
Ueda
Mitsuru
M
Hawker
Craig J
CJ