title: [Comorbidities in psoriatic patients of Iaşi Dermatological Clinic from 2004-2008].
abstract: Psoriasis is a chronic inflammatory disease of the skin, relatively frequent in the population. Recent studies have shown that psoriasis can have a great impact on quality of life, even in patients with limited disease. Although the cause of this disease remains unknown, research suggests that psoriasis is a complex disease caused by the interaction of many genes, the immune system and environmental factors. In principle, any disease can coexist with psoriasis.
  
  
  METHODS
  We conducted a retrospectiv study based on observation files of hospitalized patients with psoriasis admitted in the Dermatology Clinic Iaşi during January 2004 - December 2008.
  
  
  RESULTS
  Current data suggests that smoking and obesity increase the risk of developing psoriasis. Psoriasis may be an independent risk factor for developing diabetes, atherosclerosis and myocardial infarction. Therefore the patients with psoriasis die 3-4 years earlier than the rest of the population. Patients should be advised to stop excessive alcohol consumption and smoking.
  
  
  CONCLUSIONS
  Further studies are needed to clarify the link between severity of skin lesions, treatments and the evolution of associated diseases.
authors.affiliation: Facultatea de Medicină, Disciplina de Dermatologie, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
authors.forename: Gheucă Laura
authors.initials: GL
authors.lastname: Solovăstru
authors.forename: D
authors.initials: D
authors.lastname: Vâţă
authors.forename: Adelina Hărăţ
authors.initials: AH
authors.lastname: Batog
authors.forename: Oana
authors.initials: O
authors.lastname: Siriac
authors.forename: Alina
authors.initials: A
authors.lastname: Alupoaiei
authors.forename: Diana
authors.initials: D
authors.lastname: Diaconu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000150:complications / Q000453:epidemiology; D050197:Atherosclerosis / Q000150:complications / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D048909:Diabetes Complications / Q000453:epidemiology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000453:epidemiology; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D011565:Psoriasis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology*; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology