title: 99mTc-sestamibi scan differentiates tumor from other contrast enhancing tissue in choroid plexus tumors.
abstract: Choroid plexus tumors are rare brain tumors which account for 0.4% to 0.6% among brain tumors. Tumor resection is known to be of large prognostic impact, and re-resection of residual tumors is a part of standard care. However, after multiple resections it can become difficult to differentiate tumor from reactive tissue. 99mTC-sestamibi scans may assist in differentiating neoplastic (99mTC-sestamibi positive) from non-neoplastic tissue (99mTC-sestamibi negative). Previous literature showed sestamibi to be helpful in detecting residual choroid plexus tumors resulting in further resection. Here, we report the first case to show that sestamibi scans can also help with the opposite decision.
authors.affiliation: Departments of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: Vivek
authors.initials: V
authors.lastname: Subbiah
authors.forename: Leena
authors.initials: L
authors.lastname: Ketonen
authors.forename: Janet M
authors.initials: JM
authors.lastname: Bruner
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Nunez
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Weinberg
authors.forename: Johannes E A
authors.initials: JE
authors.lastname: Wolff
mesh_terms: D001812:Blood-Brain Barrier; D016545:Choroid Plexus Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi / Q000493:pharmacokinetics; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi