Vascular contribution to dementia in Parkinson's disease.
Parkinson's disease is one of the most common neurodegenerative diseases. Although its motor symptoms are presently relatively well controlled, other manifestations are less well understood and poorly treated. Among these, the cognitive changes have a prominent role. Dementia is usually ascribed to changes in the nucleus basalis of Meynert and the cerebral cortex. This article discusses the possible contribution of vascular factors to the cognitive impairment in Parkinson's disease and its implication for the management.
Korczyn
Amos D
AD
Sackler School of Medicine, Tel Aviv University, IL-69978 Ramat Aviv, Israel. amoskor@post.tau.ac.il
D002318:Cardiovascular Diseases / Q000150:complications*; D002319:Cardiovascular System / Q000473:pathology; D003072:Cognition Disorders / Q000209:etiology / Q000473:pathology; D003704:Dementia / Q000209:etiology* / Q000473:pathology; D006801:Humans; D010300:Parkinson Disease / Q000150:complications*