title: 4'-O-methylglycosylation of curcumin by Beauveria bassiana.
abstract: The applications of curcumin have been limited by its poor water solubility and low bioavailability. In this study, we successfully synthesized a new curcumin derivative, curcumin-8'-O-4"-O-methyl-beta-D-glucopyranoside, by biotransformation with the fungal strain Beauveria bassiana ATCC 7159. The structure of this new product was determined on the basis of spectroscopic data. This is the first record of a curcumin glycoside that has been synthesized by a fungus.
authors.affiliation: Department of Biological and Irrigation Engineering, Utah State University, Logan, UT 84322-4105, USA.
authors.forename: Jia
authors.initials: J
authors.lastname: Zeng
authors.forename: Nan
authors.initials: N
authors.lastname: Yang
authors.forename: Xiu-Min
authors.initials: XM
authors.lastname: Li
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Shami
authors.forename: Jixun
authors.initials: J
authors.lastname: Zhan
mesh_terms: D052982:Beauveria / Q000378:metabolism*; D001711:Biotransformation; D003474:Curcumin / Q000378:metabolism*; D006031:Glycosylation
chemical_list: D003474:Curcumin