title: Constituents from the seeds of Brucea javanica with inhibitory activity of Tobacco mosaic virus.
abstract: Three new constituents were obtained along with 10 known compounds from the seeds of Brucea javanica. The structures of these compounds were determined based on spectral and chemical evidence. These new compounds included a monoterpenoid glycoside and two sesquiterpenes. Bioactivity screening of these constituents showed that compounds 1, 3, 8, 9, and 13 with obvious activities in inhibiting multiplication of the Tobacco mosaic virus.
authors.affiliation: Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
authors.forename: Qi-Jian
authors.initials: QJ
authors.lastname: Chen
authors.forename: Ming-An
authors.initials: MA
authors.lastname: Ouyang
authors.forename: Qing-Wei
authors.initials: QW
authors.lastname: Tan
authors.forename: Zheng-Kun
authors.initials: ZK
authors.lastname: Zhang
authors.forename: Zu-Jian
authors.initials: ZJ
authors.lastname: Wu
authors.forename: Qi-Ying
authors.initials: QY
authors.lastname: Lin
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032269:Brucea / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014027:Tobacco Mosaic Virus / Q000187:drug effects*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D005697:Galactosides; D012717:Sesquiterpenes; D013729:Terpenes; C547892:brucojavan 1; C547893:brucojavan 2