Circulating human group A rotavirus genotypes in Malaysia.
This study examined the temporal distribution of rotavirus genotypes in Malaysia. Rotaviruses from children with diarrhea admitted to hospitals in 1996 (n = 93) and 2007 (n = 12) in two different regions of Peninsular (West) Malaysia were analyzed for their G and P genotypes using a hemi-nested RT-PCR assay. In the 2007 samples, the dominant strain was G9P[8]. It was identified in 42% of the samples. Different strains all possessing the G1 genotype were identified in the rest of the samples. In contrast, 81% of the samples collected in 1996 were the G1P[8] strain. No strains with G9 genotype were detected in samples collected in 1996.
Zuridah
H
H
Faculty of Health Sciences, Universiti Teknologi MARA, Jalan Othman, Petaling, Jaya, Selangor, Malaysia. drzuridah@salam.uitm.edu.my
Kirkwood
C D
CD
Bogdanovic-Sakran
N
N
Bishop
R F
RF
Yap
K L
KL
D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology; D005838:Genotype; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008296:Malaysia / Q000453:epidemiology; D017720:Molecular Epidemiology; D015995:Prevalence; D012401:Rotavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology*