title: Physical inactivity in patients with COPD, a controlled multi-center pilot-study.
abstract: BACKGROUND
  Physical activity (PA) has been reported to be reduced in severe chronic obstructive pulmonary disease (COPD). Studies in moderate COPD are currently scarce. The aim of the present study was to investigate physical activity in daily life in patients with COPD (n=70) and controls (n=30).
  
  
  METHODS
  A multi-center controlled study was conducted. PA was assessed using a multisensor armband device (SenseWear, BodyMedia, Pittsburgh, PA) and is reported as the average number of steps per day, and the time spent in mild and moderate physical activity.
  
  
  RESULTS
  Patients suffered from mild (n=9), moderate (n=28), severe (n=23) and very severe (n=10) COPD. The time spent in activities with mild (80 + or - 69 min vs 160 + or - 89 min, p<0.0001) and moderate intensity (24 + or - 29 min vs 65 + or - 70 min; p<0.0036) was reduced in patients compared to controls. The number of steps reached 87 + or - 34%, 71 + or - 32%, 49 + or - 34% and 29 + or - 20% of control values in GOLD-stages I to IV respectively. The time spent in activities at moderate intensity was 53 + or - 47%, 41 + or - 45%, 31 + or - 47% and 22 + or - 34% of the values obtained in controls respectively with increasing GOLD-stage. These differences reached statistical significance as of GOLD stage II (p<0.05). No differences were observed among centers.
  
  
  CONCLUSIONS
  Physical activity is reduced early in the disease progression (as of GOLD-stage II). Reductions in physical activities at moderate intensity seem to precede the reduction in the amount of physical activities at lower intensity.
authors.affiliation: Pulmonary Rehabilitation and Respiratory Division, UZ Gasthuisberg, Leuven, Belgium. Thierry.troosters@med.kuleuven.be
authors.forename: Thierry
authors.initials: T
authors.lastname: Troosters
authors.forename: Frank
authors.initials: F
authors.lastname: Sciurba
authors.forename: Salvatore
authors.initials: S
authors.lastname: Battaglia
authors.forename: Daniel
authors.initials: D
authors.lastname: Langer
authors.forename: Srinivas Rao
authors.initials: SR
authors.lastname: Valluri
authors.forename: Lavinia
authors.initials: L
authors.lastname: Martino
authors.forename: Roberto
authors.initials: R
authors.lastname: Benzo
authors.forename: David
authors.initials: D
authors.lastname: Andre
authors.forename: Idelle
authors.initials: I
authors.lastname: Weisman
authors.forename: Marc
authors.initials: M
authors.lastname: Decramer
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D018450:Disease Progression; D005080:Exercise Test / Q000523:psychology; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D010865:Pilot Projects; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology* / Q000523:psychology; D012720:Severity of Illness Index