title: Reversible sleep-related stridor during vagus nerve stimulation.
abstract: A 23-year-old woman without history of antecedent vocal, respiratory, or sleep disorders received vagus nerve stimulation (VNS) therapy for refractory partial epilepsy and developed sleep-related stridor during the course of parameter titration. Reduction of VNS current during polysomnography completely eliminated stridor. We conclude that VNS may cause sleep-related stridor in rare cases, expanding the spectrum of known sleep-disordered breathing disorders associated with VNS therapy. Parameter adjustment during polysomnography may resolve nocturnal stridor caused by VNS.
authors.affiliation: Iowa Comprehensive Epilepsy Program, Center for Sleep Medicine, Division of Pulmonary and Critical Care, Department of Medicine and Neurology, Medical Clinic and Foundation, Rochester, Minnesota 55095, USA. StLouis.Erik@mayo.edu
authors.forename: Erik K
authors.initials: EK
authors.lastname: St Louis
authors.forename: Kevin
authors.initials: K
authors.lastname: Faber
mesh_terms: D004828:Epilepsies, Partial / Q000628:therapy*; D005260:Female; D006801:Humans; D017286:Polysomnography; D012135:Respiratory Sounds / Q000209:etiology*; D012815:Signal Processing, Computer-Assisted; D012890:Sleep / Q000502:physiology*; D016896:Treatment Outcome; D055536:Vagus Nerve Stimulation / Q000009:adverse effects*; D055815:Young Adult