Perceptron learning rule derived from spike-frequency adaptation and spike-time-dependent plasticity.
It is widely believed that sensory and motor processing in the brain is based on simple computational primitives rooted in cellular and synaptic physiology. However, many gaps remain in our understanding of the connections between neural computations and biophysical properties of neurons. Here, we show that synaptic spike-time-dependent plasticity (STDP) combined with spike-frequency adaptation (SFA) in a single neuron together approximate the well-known perceptron learning rule. Our calculations and integrate-and-fire simulations reveal that delayed inputs to a neuron endowed with STDP and SFA precisely instruct neural responses to earlier arriving inputs. We demonstrate this mechanism on a developmental example of auditory map formation guided by visual inputs, as observed in the external nucleus of the inferior colliculus (ICX) of barn owls. The interplay of SFA and STDP in model ICX neurons precisely transfers the tuning curve from the visual modality onto the auditory modality, demonstrating a useful computation for multimodal and sensory-guided processing.
D'Souza
Prashanth
P
Institute of Neuroinformatics, University of Zurich and ETH Zurich, Winterthurerstrasse 190, Zurich 8057, Switzerland.
Liu
Shih-Chii
SC
Hahnloser
Richard H R
RH
D000200:Action Potentials / Q000502:physiology; D000222:Adaptation, Physiological / Q000502:physiology; D000465:Algorithms; D000818:Animals; D001307:Auditory Perception / Q000502:physiology; D001931:Brain Mapping; D007245:Inferior Colliculi / Q000166:cytology / Q000502:physiology*; D007858:Learning / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D008636:Mesencephalon / Q000166:cytology / Q000502:physiology; D008959:Models, Neurological; D016571:Neural Networks, Computer; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000502:physiology; D020305:Strigiformes / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology