[Correlation of alcohol intake with breast cancer].
Breast cancer is the most common cancer in females. Epidemiological research has shown a dose-dependent association between alcohol consumption and breast cancer incidence in women.


OBJECTIVE
The purpose of the study was to estimate the relationship between alcohol consumption in Romanian women from Transylvania geographic area and breast cancer risk.


METHODS
We have performed a case-control study on 223 patients with breast cancer, hospitalized in the Oncologic Institute "Lon Chiricuţă", Cluj-Napoca and 211 non-cancer controls, apparently healthy women, from the same geographic area. To achieve this aim we have used a validated food-frequency questionnaire, that included questions about alcoholic beverages consumption.


RESULTS
The results shows a low mean level of alcohol ingestion at both studied population groups: 5.87 g/day ethanol in breast cancer women and 4.79g/day ethanol to controls. The positive association between alcohol intake and breast cancer risk was observed for a modest level of ingestion of over 6.03 g/day ethanol (OR = 1.74, p = 0.04). The increase of alcohol intake is associated with the breast cancer risk increase (chi squared = 8.25, p for trend 0.04).


CONCLUSIONS
Reducing alcohol consumption is a potential way to reduce breast cancer risk.
Năsui
Bogdana
B
Facultatea de Medicină, Catedra de Sănătatea Mediului, Universitatea de Medicină si Farmacie "I. Haţieganu" Cluj-Napoca.
Popa
Monica
M
Curşeu
Daniela
D
Sîrbu
Dana
D
Ionuţ
Carmen
C
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D016017:Odds Ratio; D018570:Risk Assessment; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D011795:Surveys and Questionnaires