Proliferative verrucous leukoplakia, squamous cell carcinoma and axillary metastasis.
Proliferative verrucous leukoplakia (PVL) is an aggressive form of oral leukoplakia with multifocal presentation, high rates of recurrence and malignant transformation. Although development of regional lymph node metastasis is relatively frequent in patients with oral squamous cell carcinoma, axillary metastasis is quite uncommon. This paper presents a case of a 64-year-old female patient who was diagnosed with PVL and developed five oral squamous cell carcinomas and later an axillary lymph node metastasis.
Gouvêa
Adriele-Ferreira
AF
Department of Oral Diagnosis, Oral Pathology Section, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo State, Brazil. adrielefg@yahoo.com.br
Moreira
Adriana-Elisa-Brasil
AE
Reis
Rodrigo-Ribas-Dias
RR
de Almeida
Oslei-Paes
OP
Lopes
Márcio-Ajudarte
MA
D001365:Axilla; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary*; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000473:pathology* / Q000556:secondary*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*