title: Evidence for a distributed respiratory rhythm generating network in the goldfish (Carsssius auratus).
abstract: Central pattern generators located in the brainstem regulate ventilatory behaviors in vertebrates. The development of the isolated brainstem preparation has allowed these neural networks to be characterized in a number of aquatic species. The aim of this study was to explore the architecture of the respiratory rhythm-generating site in the goldfish (Carassius auratus) and to determine the utility of a newly developed isolated brainstem preparation, the Sheep Dip. Here we provide evidence for a distributed organization of respiratory rhythm generating neurons along the rostrocaudal axis of the goldfish brainstem and outline the advantages of the Sheep Dip as a tool used to survey neural networks.
authors.affiliation: Department of Physiology and Biophysics, University of Calgary, Calgary, Canada. mduchche@ucalgary.ca
authors.forename: Maryana
authors.initials: M
authors.lastname: Duchcherer
authors.forename: Andrew
authors.initials: A
authors.lastname: Kottick
authors.forename: R J A
authors.initials: RJ
authors.lastname: Wilson
mesh_terms: D000818:Animals; D001933:Brain Stem / Q000166:cytology / Q000502:physiology; D003391:Cranial Nerves / Q000502:physiology; D006054:Goldfish / Q000502:physiology*; D009415:Nerve Net / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000166:cytology; D010507:Periodicity; D015656:Respiratory Mechanics / Q000502:physiology*