[Hematological abnormalities in patients with dengue].
Dengue is a neglected disease with high morbidity and mortality among children and adults that occurs mainly in tropical and subtropical regions. The objective of this study was to evaluate hematological changes in patients with clinical manifestations of dengue. Medical records relating to 543 cases of dengue virus 3 that occurred during the 2007 epidemic in Campo Grande, Mato Grosso do Sul, were studied. Cases of classic dengue predominated (90.2%), with mild clinical manifestations lacking complications. The main hematological findings were leukopenia (68.3%), thrombocytopenia (66.5%), lymphocytopenia (67.2%) and atypical lymphocytes (67%). In dengue hemorrhagic fever, thrombocytopenia was more prolonged and the number of atypical lymphocytes was higher, while the other hematological abnormalities presented daily evolution similar to those in classic dengue. The hematological changes observed in dengue present according to the clinical course of the disease and its severity.
Oliveira
Eveny Cristine Luna de
EC
Curso de Mestrado em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS. evenycristine@yahoo.com.br
Pontes
Elenir Rose Jardim Cury
ER
Cunha
Rivaldo Venâncio da
RV
Fróes
Iris Bucker
IB
Nascimento
Delso do
Dd
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003715:Dengue / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D007970:Leukopenia / Q000821:virology*; D008297:Male; D008875:Middle Aged; D019595:Severe Dengue / Q000097:blood / Q000150:complications; D012720:Severity of Illness Index; D013921:Thrombocytopenia / Q000821:virology*; D055815:Young Adult