title: Dynamic contact angle analysis of silicone hydrogel contact lenses.
abstract: Contact angle measurements are used to infer the clinical wetting characteristics of contact lenses. Such characterization has become more commonplace since the introduction of silicone hydrogel contact lens materials, which have been associated with reduced in vivo wetting due to the inclusion of siloxane-containing components. Using consistent methodology and a single investigator, advancing and receding contact angles were measured for 11 commercially available silicone hydrogel contact lens types with a dynamic captive bubble technique employing customized, fully automated image analysis. Advancing contact angles were found to range between 20° and 72° with the lenses falling into six statistically discrete groupings. Receding contact angles fell within a narrower range, between 17° and 22°, with the lenses segregated into three groups. The relationship between these laboratory measurements and the clinical performance of the lenses requires further investigation.
authors.affiliation: Eurolens Research, Faculty of Life Sciences, The University of Manchester, Manchester, UK.
authors.forename: Michael Leonard
authors.initials: ML
authors.lastname: Read
authors.forename: Philip Bruce
authors.initials: PB
authors.lastname: Morgan
authors.forename: Jeremiah Michael
authors.initials: JM
authors.lastname: Kelly
authors.forename: Carole
authors.initials: C
authors.lastname: Maldonado-Codina
mesh_terms: D003261:Contact Lenses; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D012828:Silicones / Q000737:chemistry*; D013500:Surface Tension; D017155:Wettability
chemical_list: D012828:Silicones; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate