[Type 2 diabetes mellitus associated with pancreatic and renal malformations].
A 55-year-old woman presented with a recent diabetes mellitus associated with pancreatic and renal malformations. This atypical diabetes raised the possibility of maturity onset diabetes of the young (MODY) and a genetic research was performed. These malformations led to MODY5 diagnosis that was confirmed by the presence of HNF1beta gene mutation.
Le Berre
J-P
JP
Service d'endocrinologie, hôpital d'instruction des armées Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France. mjpleberre@free.fr
Bellanné-Chantelot
C
C
Bordier
L
L
Garcia
C
C
Dupuy
O
O
Mayaudon
H
H
Bauduceau
B
B
D015415:Biomarkers / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D005817:Genetic Counseling; D051539:Hepatocyte Nuclear Factor 1-beta / Q000235:genetics*; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D008875:Middle Aged; D009154:Mutation; D010179:Pancreas / Q000002:abnormalities*; D010641:Phenotype
D015415:Biomarkers; D051539:Hepatocyte Nuclear Factor 1-beta