title: Visualization of multiple alignments, phylogenies and gene family evolution.
abstract: Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.
authors.affiliation: University of Dundee, UK. j.procter@dundee.ac.uk
authors.forename: James B
authors.initials: JB
authors.lastname: Procter
authors.forename: Julie
authors.initials: J
authors.lastname: Thompson
authors.forename: Ivica
authors.initials: I
authors.lastname: Letunic
authors.forename: Chris
authors.initials: C
authors.lastname: Creevey
authors.forename: Fabrice
authors.initials: F
authors.lastname: Jossinet
authors.forename: Geoffrey J
authors.initials: GJ
authors.lastname: Barton
mesh_terms: D000595:Amino Acid Sequence; D005075:Biological Evolution; D020407:Internet; D008969:Molecular Sequence Data; D005810:Multigene Family; D010802:Phylogeny; D011506:Proteins / Q000737:chemistry; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins