[Molecular genetics of ovarian cancer].
Ovarian cancer is the most lethal gynecologic neoplasia. The risk of ovarian cancer in Europe is 1 to 80. In 80-90% of cases, the clinical manifestation is in advanced stage. The 5 year survival is for III /IV stage 25%, but for I/II stage is 90%. In the present study we present the molecular and genetic changes of hereditary and sporadic ovarian cancer.
Batashki
I
I
Markova
D
D
Milchev
N
N
Porjazova
E
E
Uchikov
A
A
D002277:Carcinoma / Q000235:genetics*; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics*