Small cell lung carcinoma presenting with acute disseminated encephalomyelitis.
Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease characterised by subcortical high-signal white matter lesions on T2 weighted MRI. It most commonly occurs in children following an acute viral illness. We present a case study in which ADEM was the presenting condition in an adult female with small cell lung carcinoma. We discuss the evidence in the literature suggesting that ADEM may be viewed as a paraneoplastic syndrome.
Summerfield
R
R
Department of Diagnostic Radiology, Royal Shrewsbury Hospital, Shrewsbury, Shropshire UK. summerstuff@yahoo.com
Al-Saleh
A
A
Robbins
S E
SE
D000368:Aged; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000379:methods; D016133:Polymerase Chain Reaction; D055752:Small Cell Lung Carcinoma / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods