A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery.
We demonstrated a convenient, flexible and modular synthetic approach for preparation of a small library of DNA-encapsulated supramolecular nanoparticles SNPs superset DNA and RGD-SNPs superset DNA with different sizes and RGD target ligand coverage for targeted gene delivery.
Wang
Hao
H
Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging (CIMI), University of California, Los Angeles, 570 Westwood Plazas, CNSI Building, Los Angeles, CA 90095-1770, USA. haowang@mednet.ucla.edu
Chen
Kuan-Ju
KJ
Wang
Shutao
S
Ohashi
Minori
M
Kamei
Ken-ichiro
K
Sun
Jing
J
Ha
Ji Hoon
JH
Liu
Kan
K
Tseng
Hsian-Rong
HR
D000818:Animals; D002460:Cell Line; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D018014:Gene Transfer Techniques; D006801:Humans; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D011092:Polyethylene Glycols / Q000737:chemistry
D009842:Oligopeptides; D011092:Polyethylene Glycols; C047981:arginyl-glycyl-aspartic acid; D004247:DNA