Pharmaceutically used polymers: principles, structures, and applications of pharmaceutical delivery systems.
This chapter presents a general overview of pharmaceutically used polymers with respect to their physicochemical characteristics and factors affecting drug delivery abilities. Pharmaceutical polymers, chemical structure, and properties are discussed for their applications in controlled drug release systems. An additional focus is on new polymers (dendrimers, hyperbranched polymers), considering their chemical versatility, uniqueness, and future implications. Problems associated with controlled drug release systems are also highlighted. Finally, applications of FDA-approved polymers used for oral drug delivery systems are outlined.
Khandare
Jayant
J
Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
Haag
Rainer
R
D000284:Administration, Oral; D003692:Delayed-Action Preparations; D050091:Dendrimers / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry*; D016503:Drug Delivery Systems; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D011108:Polymers / Q000737:chemistry*
D003692:Delayed-Action Preparations; D050091:Dendrimers; D004337:Drug Carriers; D004364:Pharmaceutical Preparations; D011108:Polymers