Remarkable anion effects uncovered in the development of a Au(III)-catalyzed tandem nucleophilic substitution-1,5-enyne cycloisomerization process.
(I(t)Pe)AuBr(2)(N-imidate) complexes, prepared in high yield by oxidative bromination, are active catalysts for 1,5-enyne cycloisomerization. An efficient tandem nucleophilic substitution-1,5-enyne cycloisomerization is promoted by these novel Au(III) precatalysts. Catalyst efficacy is affected by the imidate ligand and the silver salt used (e.g. Ag[Al(OC(CF(3))(3))(4)]).
Reeds
Jonathan P
JP
Department of Chemistry, University of York, Heslington, York, UK YO10 5DD.
Whitwood
Adrian C
AC
Healy
Mark P
MP
Fairlamb
Ian J S
IJ
D000838:Anions; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D007536:Isomerism; D008024:Ligands; D008958:Models, Molecular
D000838:Anions; D008024:Ligands; D006046:Gold