[Influenza vaccines adjuvants--contemporary state].
Data on development and study of adjuvants for influenza vaccines against avian and seasonal influenza are presented. Requirements to perspective adjuvants, their main groups (mineral salts of aluminium, squalene derivatives, polyglycosides, and immunomodulators) as well as experimental adjuvants are reviewed. Analysis of results of several clinical trials of adjuvanted vaccines against avian influenza is presented. On the basis of published data analysis conclusion about good perspective of influenza vaccines with new adjuvants was made.
Vasil'ev
Iu M
IuM
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000737:chemistry / Q000145:classification; D000818:Animals; D001717:Birds; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D005585:Influenza in Birds / Q000517:prevention & control*; D007251:Influenza, Human / Q000517:prevention & control*
D000276:Adjuvants, Immunologic; D007252:Influenza Vaccines