title: [STOPP-START: adaptation of a French language screening tool for detecting inappropriate prescriptions in older people].
abstract: OBJECTIVE
  STOPP-START is a screening tool for detecting inappropriate prescriptions in older people. Recently validated in its English-language version, it is a reliable and easy-to-use tool, allowing assessment of prescription drugs often described as inappropriate (STOPP) or unnecessarily underused (START) in this population. An adaptation of the tool into French language is presented here.
  
  
  METHODS
  A translation-back translation method, with validation of the obtained version by French-speaking experts from Belgium, Canada, France and Switzerland, has been used. An inter-rater reliability analysis completed the validation process. Fifty data sets of patients hospitalized in an academic geriatrics department (mean age +/- standard deviation: 77.6 +/- 7.9 years; 70% were women) were analyzed independently by one geriatrician and one general practitioner.
  
  
  RESULTS
  The adaptation in French considers the 87 STOPP-START criteria of the original version. They are all organized according to physiological systems. The 50 data sets involved 418 prescribed medications (median 8; inter-quartile range 5-12). The proportions of positive and negative inter-observer agreements were 99% and 95% respectively for STOPP, and 99% and 88% for START; Cohen's kappa-coefficients were 0.95 for STOPP and 0.92 for START. These results indicated an excellent inter-rater agreement.
  
  
  CONCLUSIONS
  Therefore, this French language version of STOPP-START is as reliable as the original English language version of the tool. For STOPP-START to have tangible clinical benefit to patients, a randomized controlled trial must be undertaken to demonstrate efficacy in the prevention of adverse clinical events connected with inappropriate prescriptions.
authors.affiliation: Service de Gériatrie, Département de réhabilitation et gériatrie, Hôpitaux Universitaires et faculté de médecine de Genève, Suisse. pierre.o.lang@hcuge.ch
authors.forename: Pierre-Olivier
authors.initials: PO
authors.lastname: Lang
authors.forename: Yasmine
authors.initials: Y
authors.lastname: Hasso
authors.forename: Joël
authors.initials: J
authors.lastname: Belmin
authors.forename: Isabelle
authors.initials: I
authors.lastname: Payot
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Baeyens
authors.forename: Nicole
authors.initials: N
authors.lastname: Vogt-Ferrier
authors.forename: Paul
authors.initials: P
authors.lastname: Gallagher
authors.forename: Denis
authors.initials: D
authors.lastname: O'Mahony
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Michel
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D011307:Drug Prescriptions; D064420:Drug-Related Side Effects and Adverse Reactions; D005060:Europe; D005260:Female; D005602:France; D006801:Humans; D007802:Language; D008297:Male; D015813:Substance Abuse Detection / Q000295:instrumentation*; D014175:Translating