title: [Low-dose tadalafil improves arterial erectile dysfunction].
abstract: OBJECTIVE
  To evaluate the effect of low-dose phosphodiesterase type 5 inhibitor tadalafil on arterial erectile dysfunction.
  
  
  METHODS
  Forty-three patients with arterial erectile dysfunction were requested to take 5 mg tadalafil after supper on alternate days for 4 weeks. All the patients were scored on IIEF-5 and received intracavernous injection of 10 microg prostaglandin E1, followed by measurement of the peak systolic velocity (PSV) of the cavernosal artery by color Doppler ultrasonography.
  
  
  RESULTS
  Statistic analyses showed an obvious increase in the IIEF-5 score and PSV after the treatment, with significant differences from the baseline (P < 0.01).
  
  
  CONCLUSIONS
  Low-dose tadalafil can significantly improve the PSV of the cavernosal artery and hence the erectile function of arterial ED patients.
authors.affiliation: Department of Andrology, Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008, China. xuzhipengyi@163.com
authors.forename: Zhi-Peng
authors.initials: ZP
authors.lastname: Xu
authors.forename: Yun
authors.initials: Y
authors.lastname: Chen
authors.forename: Chao
authors.initials: C
authors.lastname: Sun
authors.forename: Yu-Tian
authors.initials: YT
authors.lastname: Dai
mesh_terms: D000328:Adult; D000368:Aged; D001158:Arteries; D002243:Carbolines / Q000008:administration & dosage* / Q000627:therapeutic use; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000008:administration & dosage* / Q000627:therapeutic use; D000068581:Tadalafil
chemical_list: D002243:Carbolines; D010726:Phosphodiesterase Inhibitors; D000068581:Tadalafil