title: Dietary patterns and risk of oral and pharyngeal cancer: a case-control study in Rio de Janeiro, Brazil.
abstract: The study investigated the association between dietary patterns and oral cancer as part of a Latin American multicenter hospital-based case-control study, and included 210 incident cases of oral cancer and 251 controls. Dietary data were collected using a Food Frequency Questionnaire (FFQ). Factor analysis was used to define dietary patterns, which were categorized into terciles. Odds ratios (OR) with 95% confidence intervals (95%CI) were calculated using unconditional multiple logistic regression. The patterns 'prudent', characterized mainly by vegetables and fruits, and 'traditional', by rice, and pulses showed an inverse association with oral cancer for the higher tercile, respectively, OR = 0.44; 95%CI: 0.25-0.75, p value for trend (p tend) = 0.03; OR = 0.53; 95%CI: 0.30-0.93, p tend = 0.06. The 'snacks pattern' was not associated with oral cancer. Besides the protective effect of a diet rich in vegetables and fruit, our data suggest that the traditional Brazilian diet, consisting mostly of rice and beans, may improve protection against oral cancer.
authors.affiliation: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
authors.forename: Ana Lucia Araujo de
authors.initials: AL
authors.lastname: Toledo
authors.forename: Rosalina Jorge
authors.initials: RJ
authors.lastname: Koifman
authors.forename: Sergio
authors.initials: S
authors.lastname: Koifman
authors.forename: Dirce Maria Lobo
authors.initials: DM
authors.lastname: Marchioni
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil; D016022:Case-Control Studies; D004032:Diet / Q000706:statistics & numerical data*; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology* / Q000517:prevention & control; D010610:Pharyngeal Neoplasms / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors