title: Pd-catalyzed decarboxylative arylation of thiazole, benzoxazole, and polyfluorobenzene with substituted benzoic acids.
abstract: A Pd-catalyzed decarboxylative coupling of thiazoles and benzoxazole with various substituted benzoic acids is developed. The reaction is compatible with both electron-rich and electron-poor benzoic acids. It can also be extended to the synthesis of polyfluoro-substituted biaryls using polyfluorobenzenes as the starting materials.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Xie
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Yang
authors.forename: Xingjian
authors.initials: X
authors.lastname: Zhou
authors.forename: Xiujian
authors.initials: X
authors.lastname: Li
authors.forename: Sizhuo
authors.initials: S
authors.lastname: Wang
authors.forename: Ze
authors.initials: Z
authors.lastname: Tan
authors.forename: Xiangyu
authors.initials: X
authors.lastname: An
authors.forename: Can-Cheng
authors.initials: CC
authors.lastname: Guo
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D001583:Benzoxazoles / Q000737:chemistry*; D002384:Catalysis; D003653:Decarboxylation; D005464:Fluorobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013844:Thiazoles / Q000737:chemistry*
chemical_list: D001565:Benzoates; D001583:Benzoxazoles; D005464:Fluorobenzenes; D013844:Thiazoles; D010165:Palladium