title: [Cholangiocarcinoma with bile duct adenoma and hamartoma-like lesion in the bile duct].
abstract: A 76-year-old man presented with fever of unknown origin. Diagnostic imaging showed a liver tumor measuring 3cm in maximum dimension. The tumor was subsequently resected, and histopathology showed a moderately differentiated adenocarcinoma. This showed a number of bile ductules with variable amounts of stroma, well circumscribed but not encapsulated, so the lesion was diagnosed as a cholangiocarcinoma. Within the tumor there was also a cholangiolocarcinoma-like lesion. In addition, cystically dilated ductules resembling bile duct hamartoma and bile duct adenoma adjacent to the tumor were found, but with no area of transition among them. In the Glisson's capsule around the tumor, there was also a bile duct hamartoma.
authors.affiliation: Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan. sho@sapmed.ac.jp
authors.forename: Sho
authors.initials: S
authors.lastname: Takahashi
authors.forename: Kohichi
authors.initials: K
authors.lastname: Takada
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kawano
authors.forename: Koji
authors.initials: K
authors.lastname: Miyanishi
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Ishiwatari
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Sagawa
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sato
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sato
authors.forename: Rishu
authors.initials: R
authors.lastname: Takimoto
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kobune
authors.forename: Ganji
authors.initials: G
authors.lastname: Kuroiwa
authors.forename: Michiaki
authors.initials: M
authors.lastname: Hirayama
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Tobioka
authors.forename: Kouichi
authors.initials: K
authors.lastname: Hirata
authors.forename: Mutsuko
authors.initials: M
authors.lastname: Omatsu
authors.forename: Tadashi
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Junji
authors.initials: J
authors.lastname: Kato
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000473:pathology*; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*