title: Patterned multiplex pathogen DNA detection by Au particle-on-wire SERS sensor.
abstract: A Au particle-on-wire system that can be used as a specific, sensitive, and multiplex DNA sensor is developed. A pattern formed by multiple Au nanowire sensors provides positional address and identification for each sensor. By using this system, multiplex sensing of target DNAs was possible in a quantitative manner with a detection limit of 10 pM. Target DNAs from reference bacteria and clinical isolates were successfully identified by this sensor system, enabling diagnostics for infectious diseases.
authors.affiliation: Department of Chemistry, KAIST, Daejeon, Korea.
authors.forename: Taejoon
authors.initials: T
authors.lastname: Kang
authors.forename: Seung Min
authors.initials: SM
authors.lastname: Yoo
authors.forename: Ilsun
authors.initials: I
authors.lastname: Yoon
authors.forename: Sang Yup
authors.initials: SY
authors.lastname: Lee
authors.forename: Bongsoo
authors.initials: B
authors.lastname: Kim
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004269:DNA, Bacterial / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D053770:Nanowires / Q000737:chemistry*; D010316:Particle Size; D012680:Sensitivity and Specificity; D013499:Surface Properties
chemical_list: D004269:DNA, Bacterial; D006046:Gold