title: Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment.
abstract: Cerebral amyloid angiopathy (CAA) is a common but often asymptomatic disease, characterized by deposition of amyloid in cerebral blood vessels. We describe the successful treatment of CAA encephalopathy with dexamethasone in a patient with CAA-related inflammation causing subacute progressive encephalopathy and seizures, which is an increasingly recognized subtype of CAA. The two pathological subtypes of CAA-related inflammation are described and a review of the literature is performed concerning immunosuppressive treatment of CAA-related inflammation with special attention to its pathological subtypes. Immunosuppressive therapy appears to be an appropriate treatment for CAA encephalopathy.
authors.affiliation: Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Raoul P
authors.initials: RP
authors.lastname: Kloppenborg
authors.forename: Edo
authors.initials: E
authors.lastname: Richard
authors.forename: Marieke E S
authors.initials: ME
authors.lastname: Sprengers
authors.forename: Dirk
authors.initials: D
authors.lastname: Troost
authors.forename: Piet
authors.initials: P
authors.lastname: Eikelenboom
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Nederkoorn
mesh_terms: D000368:Aged; D016657:Cerebral Amyloid Angiopathy / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D013256:Steroids / Q000627:therapeutic use*
chemical_list: D013256:Steroids