Free breathing cardiac real-time cine MR without ECG triggering.
The increasing frequency of LV functional MRI studies demands for faster methods and for more comfort for the patient. We tested, whether real-time (RT) non ECG triggered MRI allows a considerable shortening of examination time in high reproducibility. RT and standard ECG-triggered breathhold cine MRI was acquired in 9 volunteers and 21 patients. Differences between both methods were assessed by Bland-Altman analyses including variability studies. Compared to standard cine MRI, RT decreased data acquisition time by more than the factor of ten. RT produced comparable results (e.g. EF in %: +0.67 [-5.63, 6.97]) except for a slight overestimation of LV mass. Interstudy and intraobserver variability of RT cine showed a low variability. Consequently, free-breathing RT cine proved to be a reliable and suitable tool for clinical routine and may be particularly relevant in patients with sub-optimal breath-holding ability and arrhythmia.
Beer
Meinrad
M
Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany. Electronic address: beer@roentgen.uni-wuerzburg.de.
Stamm
Heimo
H
Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Machann
Wolfram
W
Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Weng
Andreas
A
Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Goltz
Jan P
JP
Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Breunig
Frank
F
Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Weidemann
Frank
F
Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Hahn
Dietbert
D
Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
Köstler
Herbert
H
Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
D000328:Adult; D000368:Aged; D003199:Computer Systems; D003964:Diaphragm / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*; D055815:Young Adult