title: Epizootic fatal amebiasis in an outdoor group of Old World monkeys.
abstract: BACKGROUND
  Entamoeba (E.) histolytica is an obligate parasite of humans and non-human primates.
  
  
  METHODS
  This report describes the pathomorphological, immunohistological, and microbiological findings of fatal E. histolytica infection in two mantled guerezas (Colobus guereza) and one Hanuman langur (Semnopithecus entellus) from an epizootic outbreak of amebiasis in an open-range recreation park.
  
  
  RESULTS
  Pathomorphological examination revealed multifocal necrotizing and granulomatous hepatitis with intralesional protozoan trophozoites in all three cases. In addition, necrotizing and ulcerative gastritis was detected in both mantled guerezas. Furthermore, oligofocal acute pulmonary embolization was detected in one of these cases. No extra-hepatic lesions were observed in the Hanuman langur. Immunohistological examination confirmed the etiologic diagnosis of E. histolytica-induced lesions.
  
  
  CONCLUSIONS
  Although E. histolytica is a rarely diagnosed pathogen in Western European countries, veterinarians and animal keepers involved in handling and care taking of non-human primates should be aware of the potential threat caused by this zoonotic parasite.
authors.affiliation: Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg, Hannover, Germany. reiner.ulrich@tiho-hannover.de
authors.forename: Reiner
authors.initials: R
authors.lastname: Ulrich
authors.forename: Michael
authors.initials: M
authors.lastname: Böer
authors.forename: Vanessa
authors.initials: V
authors.lastname: Herder
authors.forename: Ingo
authors.initials: I
authors.lastname: Spitzbarth
authors.forename: Marion
authors.initials: M
authors.lastname: Hewicker-Trautwein
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Baumgärtner
authors.forename: Peter
authors.initials: P
authors.lastname: Wohlsein
mesh_terms: D000562:Amebiasis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D003104:Colobus; D004748:Entamoeba histolytica / Q000302:isolation & purification; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry; D008099:Liver / Q000473:pathology; D008297:Male; D013270:Stomach / Q000473:pathology