New technologies for application to veterinary therapeutics.
The purpose of this contribution is to review new technologies and make an educated prediction as to how they will impact veterinary pharmacology over the coming decades. By examining past developments, it becomes evident that change is incremental and predictable unless either a transforming discovery or a change in societal behaviour occurs. In the last century, both discoveries and behaviours have dramatically changed medicine, pharmacology and therapeutics. In this chapter, the potential effects of six transforming technologies on veterinary therapeutics are examined: continued advances in computer technology, microfluidics, nanotechnology, high-throughput screening, control and targeted drug delivery and pharmacogenomics. These should lead to the more efficacious and safer use of existing medicants, and the development of novel drugs across most therapeutic classes through increases in our knowledge base, as well as more efficient drug development. Although this growth in technology portends major advances over the next few decades, economic and regulatory constraints must still be overcome for these new drugs or therapeutic approaches to become common practise.
Riviere
Jim E
JE
Center for Chemical Toxicology Research and Pharmacokinetics, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA. Jim_Riviere@ncsu.edu
D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004358:Drug Therapy / Q000639:trends / Q000662:veterinary; D004360:Drug Therapy, Computer-Assisted / Q000379:methods / Q000662:veterinary; D006801:Humans; D044085:Microfluidics; D036103:Nanotechnology / Q000639:trends; D010597:Pharmacogenetics / Q000639:trends; D010600:Pharmacology / Q000639:trends*; D014730:Veterinary Medicine / Q000639:trends*