title: [Genetic and social factors in developing of aggression].
abstract: The association of 5-HTTLPR gene polymorthism and aggression was studied in control group of males and females and in the athletes. The sport activities were found to decrease the aggression: the effect persist for the synchronized swimmers and for the wrestlers. Control group of males were characterized by higher aggression scores (Assault, Negativism, Suspicion and Verbal aggression scales of Buss-Durkee Hostility Inventory) compared to females. For all female-subjects irrespective of sport activities and age, the association between the variants of 5-HTTLPR gene and the Indirect Aggression and Negativism scores were found: carries of SS genotype has higher scores on Indirect Aggression and lower scores on Negativism. For the males the association was different: The averaged Hostility scores were higher for the carriers of LL-genotype. The brain processes, presumably underlying the association between aggression and 5-HTLPR gene, were studied in male control group. The increased MMN component of ERP, which responsible for the automatic change detection, and decreased P3a component, related to involuntary attention and cognitive control were found in LL-carries. It might be considered as a sign that SS-carries process the information with more cognitive resources. Probably they perceive the stimulus as more complicated, which lead to activation the additional resources of frontal cortex. It might be also suggested that the carries of SS-genotype tend to deeper processing of the incoming information. Probably, it is this more "serious" analysis of external information, which underlies the rejection of impulsive aggressive actions.
authors.forename: O V
authors.initials: OV
authors.lastname: Sysoeva
authors.forename: M A
authors.initials: MA
authors.lastname: Kulikova
authors.forename: N V
authors.initials: NV
authors.lastname: Maliuchenko
authors.forename: A G
authors.initials: AG
authors.lastname: Tonevitskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Ivanitskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000374:Aggression; D002648:Child; D003071:Cognition; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics*; D012931:Social Environment; D012959:Socioeconomic Factors
chemical_list: C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins