title: Evaluation of aqueous preparations from herbal drugs.
abstract: The paper presents results obtained within analysis of aqueous preparations obtained from the herbal drugs, (APHD) which are available in pharmacy as mass produced drugs. In particular, the following drugs were analyzed: CYNAROFIT, L'ALIAFIT, Tinctura belladonnae, Tinctura gentianae, Tinctura chinae a Tinctura valerianae made by Calendula, j.s.c.--Slovakia and Tinctura valerianae made by IVAX-Czech republic. Tictura valerianae magistraliter was prepared in a laboratory. The APHDs were analyzed under the following aspects: amount of dry matter, density, index of refraction, pH value, content of ethanol, influence of the light on these parameters as well as the global appearance of samples. In parallel to that, the stability of samples Tinctura valerianae prepared by two different manufacturers and the samples of magistraliter preparations were compared. It was found that storing samples delivered by Calendula j.s.c. does not significantly influenced their stability neither in the light nor in the dark, kept at the temperature of 20-25 degrees C over the time interval of 6 months. All samples were in agreement with the norms of companies as well as with both Czechoslovak (CSL 4) and Slovak (SL 1) pharmacopoeias. Besides, the results obtained show that a kind of extraction methods (percolation, maceration) does not influence neither quality nor stability of the samples Tinctura valerianae.
authors.affiliation: Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University, Odbojárov 10, 832 32 Bratislava, Slovakia.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Vitková
authors.forename: Bronislava
authors.initials: B
authors.lastname: Brázdovicová
authors.forename: Katarína
authors.initials: K
authors.lastname: Ralbovská
authors.forename: Andrea
authors.initials: A
authors.lastname: Halenárová
mesh_terms: D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D028321:Plant Preparations / Q000737:chemistry*; D011786:Quality Control; D012997:Solvents / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods; D013696:Temperature; D013997:Time Factors; D014867:Water / Q000737:chemistry*
chemical_list: D028321:Plant Preparations; D012997:Solvents; D014867:Water