title: Strong analgesics: working towards an optimal balance between efficacy and side effects.
authors.forename: Giustino
authors.initials: G
authors.lastname: Varrassi
authors.forename: Franco
authors.initials: F
authors.lastname: Marinangeli
authors.forename: Alba
authors.initials: A
authors.lastname: Piroli
authors.forename: Stefano
authors.initials: S
authors.lastname: Coaccioli
authors.forename: Antonella
authors.initials: A
authors.lastname: Paladini
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use*; D002908:Chronic Disease; D017322:Clinical Trials, Phase II as Topic; D017326:Clinical Trials, Phase III as Topic; D004359:Drug Therapy, Combination; D006801:Humans; D010146:Pain / Q000150:complications* / Q000188:drug therapy*; D010636:Phenols / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D017450:Receptors, Opioid, mu / Q000819:agonists; D000077432:Tapentadol
chemical_list: D000701:Analgesics, Opioid; D010636:Phenols; D017450:Receptors, Opioid, mu; D000077432:Tapentadol