title: Cervid herpesvirus 2 infection in reindeer: a review.
abstract: Herpesviruses of the genus Varicellovirus are known to infect and cause disease in a variety of ruminant species, but the impact of cervid herpesvirus 2 (CvHV2) in reindeer (Rangifer tarandus) is mostly unknown. Reindeer is a circum-polar species with a total estimated number of more than 5 million animals. Mortality may reach high values, as in northern Norway, especially in calves (37%; 2005-2006), and disease can potentially account for some of this mortality. CvHV2 has been isolated during a natural outbreak of infectious keratoconjunctivitis, indicating an etiologal link. Serological screening has shown that CvHV2 infection is prevalent in Northern Norway and experimental infection studies have demonstrated that viremia, latency and vertical transmission occur for CvHV2. The present review aims at summarizing current knowledge on the epidemiology, pathogenesis and molecular virology of CvHV2.
authors.affiliation: Section of Arctic Veterinary Medicine, Department of Food Safety and Infection Biology, The Norwegian School of Veterinary Science, Stakkevollveien 23, NO - 9010 Tromsø, Norway. carlos.neves@veths.no
authors.forename: Carlos G
authors.initials: CG
authors.lastname: das Neves
authors.forename: Swaantje
authors.initials: S
authors.lastname: Roth
authors.forename: Espen
authors.initials: E
authors.lastname: Rimstad
authors.forename: Etienne
authors.initials: E
authors.lastname: Thiry
authors.forename: Morten
authors.initials: M
authors.lastname: Tryland
mesh_terms: D000818:Animals; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary* / Q000821:virology; D007639:Keratoconjunctivitis, Infectious / Q000821:virology; D012053:Reindeer / Q000821:virology*; D018140:Varicellovirus / Q000502:physiology*