Propofol: thriller or killer.
Known by the proprietary name Diprivan or its generic name propofol, this anesthetic drug is among the most widely used sedatives in the United States. Propofol has a unique pharmacologic profile, making it an ideal drug for use in plastic surgery nursing. Propofol is utilized as an anesthetic induction agent and sedative during many plastic surgeries. This article explores indications, pharmacokinetics, adverse effects, and potential abuse of propofol.
McCarver
Lewis
L
Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA. lewis.mccarver@vanderbilt.edu
Spear
Marcia
M
D018686:Anesthetics, Intravenous / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D015742:Propofol / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D019966:Substance-Related Disorders; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D018686:Anesthetics, Intravenous; D005680:gamma-Aminobutyric Acid; D015742:Propofol