title: Percutaneous PFO closure using the Premere device occluder: initial experience.
abstract: BACKGROUND
  Most data on percutaneous closure of patent foramen ovale (PFO) relate to devices not specifically designed for this pathology.
  
  
  OBJECTIVE
  Our aim in this article is to share our initial experience with the Premere PFO closure system.
  
  
  METHODS
  In our hospital 14 consecutive patients presenting cryptogenic stroke underwent percutaneous closure using this device. The device was successfully implanted in 11 of the 14 patients (78.5%). Implantation was impossible in three patients because of a significant atrial septal aneurysm (ASA) or a multiperforated septum.
  
  
  RESULTS
  Mean clinical and echocardiographical follow-up was 7 +/- 7 months. A residual shunt was seen in only one patient (9%) three months after device implantation. During follow-up, no device-related complications were observed, such as device thrombosis or fistula. None of the patients presented other significant clinical events such as strokes or arrhythmia.
  
  
  CONCLUSIONS
  According to our experience the Premere is a secure and reliable device for PFO closure, but patients must be selected carefully for implantation to exclude those presenting significant ASA.
authors.affiliation: Unidad de Cardiología Intervencionista, Hospital La Paz, Madrid, Espanha.
authors.forename: Roberto
authors.initials: R
authors.lastname: Martin Reyes
authors.forename: Guillermo
authors.initials: G
authors.lastname: Galeote
authors.forename: Raul
authors.initials: R
authors.lastname: Moreno
authors.forename: Luis
authors.initials: L
authors.lastname: Calvo
authors.forename: Alexis
authors.initials: A
authors.lastname: Villate
authors.forename: Mauricio
authors.initials: M
authors.lastname: Vanegas
authors.forename: Angel
authors.initials: A
authors.lastname: Sanchez-Recalde
authors.forename: Santiago
authors.initials: S
authors.lastname: Jiménez-Valero
authors.forename: Teresa
authors.initials: T
authors.lastname: Lopez
authors.forename: Mar
authors.initials: M
authors.lastname: Moreno
authors.forename: Anastasio
authors.initials: A
authors.lastname: Gonzaga
authors.forename: Isidro
authors.initials: I
authors.lastname: Moreno-Gomez
authors.forename: Jose-Luis
authors.initials: JL
authors.lastname: Lopez-Sendón
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D054092:Foramen Ovale, Patent / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055989:Septal Occluder Device