title: Protein crystallizability.
abstract: Obtaining well-diffracting crystals remains a major challenge in protein structure research. In this chapter, we review currently available computational methods to estimate the crystallization potential of a protein, to optimize amino acid sequences toward improved crystallization likelihood, and to design optimal crystal screen conditions.
authors.affiliation: MIPS & Helmholz Institute München, Martinsried, Germany.
authors.forename: Pawel
authors.initials: P
authors.lastname: Smialowski
authors.forename: Dmitrij
authors.initials: D
authors.lastname: Frishman
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D000818:Animals; D019295:Computational Biology; D003460:Crystallization; D057225:Data Mining; D030562:Databases, Protein; D006801:Humans; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D020539:Sequence Analysis, Protein
chemical_list: D011506:Proteins