title: Head and neck sarcoma: report of a case treated by intensity-modulated radiation therapy.
abstract: We report on a 71-year-old woman with parapharyngeal sarcoma. Surgery could not be performed because of the size and location of the tumor. After failure of four cycles of chemotherapy, intensity-modulated radiation therapy (IMRT) achieved complete clinical response and partial magnetic resonance imaging response (80%) at 24 months of follow-up. The results of radiotherapy, especially IMRT, for nonresectable head and neck soft tissue sarcoma are discussed.
authors.affiliation: Léon Bérard Cancer Center, 28 Rue Laennec, 69008, Lyon, France. pierreheudel@yahoo.fr
authors.forename: Pierre
authors.initials: P
authors.lastname: Heudel
authors.forename: Marie Claude
authors.initials: MC
authors.lastname: Biston
authors.forename: Jérome
authors.initials: J
authors.lastname: Fayette
authors.forename: Antoine
authors.initials: A
authors.lastname: Ramade
authors.forename: Frédéric
authors.initials: F
authors.lastname: Gassa
authors.forename: Pascal
authors.initials: P
authors.lastname: Pommier
mesh_terms: D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D019583:Dose Fractionation, Radiation; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010614:Pharynx; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated; D012509:Sarcoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin