Copper(II)-catalyzed ortho-acyloxylation of the 2-arylpyridines sp(2) C-H bonds with anhydrides, using O(2) as terminal oxidant.
A chelation-assisted copper(II)-catalyzed ortho-acyloxylation of the 2-arylpyridine sp(2) C-H bond with anhydride is described. The procedure tolerates various functional groups, such as carbomethoxyl, methoxyl, fluoro, bromo, chloro, and cyano groups, affording the mono- or diacyloxylated products in moderate to good yields. Importantly, this procedure uses O(2) as a clean terminal oxidant.
Wang
Wenhui
W
College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325027, People's Republic of China.
Luo
Fang
F
Zhang
Shouhui
S
Cheng
Jiang
J