Biological activity of phenolic lipids.
Phenolic lipids are a very diversified group of compounds derived from mono and dihydroxyphenols, i.e., phenol, catechol, resorcinol, and hydroquinone. Due to their strong amphiphilic character, these compounds can incorporate into erythrocytes and liposomal membranes. In this review, the antioxidant, antigenotoxic, and cytostatic activities of resorcinolic and other phenolic lipids are described. The ability of these compounds to inhibit bacterial, fungal, protozoan and parasite growth seems to depend on their interaction with proteins and/or on their membrane-disturbing properties.
Stasiuk
Maria
M
Department of Lipids and Liposomes, University of Wroclaw, Poland. stasiuk@ibmb.uni.wroc.pl
Kozubek
A
A
D000818:Animals; D016587:Antimutagenic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D008055:Lipids / Q000737:chemistry / Q000494:pharmacology*; D019800:Phenol / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*
D016587:Antimutagenic Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D008055:Lipids; D019800:Phenol