title: An overview of the processes shaping protein evolution.
abstract: From a comparatively small number of protein structural domains a staggering array of structural variants has evolved which has, in turn, facilitated an expanse of functional derivatives. Herein I review the primary mechanisms which have contributed to the vastness of our existing, and expanding, protein repertoires.
authors.affiliation: Department of Biological Sciences, Cork Institute of Technology. Roy.sleator@cit.ie
authors.forename: Roy D
authors.initials: RD
authors.lastname: Sleator
mesh_terms: D019143:Evolution, Molecular; D020440:Gene Duplication; D014644:Genetic Variation; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000235:genetics*; D011995:Recombination, Genetic
chemical_list: D011506:Proteins