title: Design and efficient synthesis of a new scaffold based on unsymmetrical protoporphyrin IX derivatives for use in SPPS.
abstract: Fmoc-protected amine derivatives of Protoporphyrin IX were synthesized by two original methods using solid-phase chemistry. The new compounds represent unsymmetrical scaffolds suitable for the generation of a large range of peptidic porphyrin derivatives through SPPS strategy.
authors.affiliation: Université de Limoges, Laboratoire de Chimie des Substances Naturelles, EA 1069 Faculté des Sciences et Techniques, 123 Avenue Albert Thomas, 87060 Limoges, France.
authors.forename: M-E
authors.initials: ME
authors.lastname: Bakleh
authors.forename: V
authors.initials: V
authors.lastname: Sol
authors.forename: R
authors.initials: R
authors.lastname: Granet
authors.forename: G
authors.initials: G
authors.lastname: Déléris
authors.forename: K
authors.initials: K
authors.lastname: Estieu-Gionnet
authors.forename: P
authors.initials: P
authors.lastname: Krausz
mesh_terms: D004951:Esterification; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry*; D011524:Protoporphyrins / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010455:Peptides; D011524:Protoporphyrins; C028025:protoporphyrin IX