title: Pyroptosis - a cell death modality of its kind?
abstract: The term "pyroptosis" was originally introduced to describe a particular form of cell death in macrophages, which is induced by bacterial infection, is accompanied by caspase-1 activation and hence leads to the release of pyrogenic interleukins; however, it is still controversial whether pyroptosis - which can also be triggered by non-bacterial pathological stimuli - truly represents a cell death modality on its own or whether it constitutes a special case of apoptosis or necrosis.
authors.affiliation: INSERM, U848, Villejuif, France.
authors.forename: Oliver
authors.initials: O
authors.lastname: Kepp
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Galluzzi
authors.forename: Laurence
authors.initials: L
authors.lastname: Zitvogel
authors.forename: Guido
authors.initials: G
authors.lastname: Kroemer
mesh_terms: D000818:Animals; D016923:Cell Death / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D046912:Multiprotein Complexes / Q000276:immunology*
chemical_list: D046912:Multiprotein Complexes