[An update of biomarkers in prostate cancer tissue].
The development of biomarkers for prostate cancer screening, detection and prognosis has greatly decreased the mortality of this disease. Recently, some new views on such biomarkers as PSMA, CK34betaE12, p63, AMACR, Pca-24, hTERT, DD3, Annexin A3 and GSTP1 methylation in prostate cancer tissue have been re-identified and investigated. Future research should focus on the combined screening of multiple biomarkers and discovery of new ones, which may possibly improve the sensitivity, specificity and accuracy of the early detection of prostate cancer.
Wang
Yong-Chuan
YC
Department of Urology, The First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China.
Xia
Shu-Jie
SJ
D014408:Biomarkers, Tumor; D042241:Early Diagnosis; D006801:Humans; D008297:Male; D008745:Methylation; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*
D014408:Biomarkers, Tumor