Onychomadesis: a rare side-effect of valproic acid medication?
Valproic acid (VPA) is frequently used as an antiepileptic drug. Several side effects are known. We report on a child with onychomadesis as a possible side-effect of treatment with VPA. Normal nail growth was observed after stopping VPA. The pathomechanism of onychomadesis due to VPA treatment remains unclear.
Poretti
Andrea
A
Paediatric Neurology, University Children's Hospital of Zurich, CH-8032Zurich, Switzerland. andrea.poretti@kispi.uzh.ch
Lips
Ulrich
U
Belvedere
Marco
M
Schmitt
Bernhard
B
D000927:Anticonvulsants / Q000009:adverse effects*; D002675:Child, Preschool; D004831:Epilepsies, Myoclonic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000139:chemically induced*; D009262:Nails / Q000187:drug effects* / Q000254:growth & development; D014635:Valproic Acid / Q000009:adverse effects*
D000927:Anticonvulsants; D014635:Valproic Acid