Concise total synthesis of (+/-)-lycopladine A.
A concise total synthesis of the Lycopodium alkaloid lycopladine A (1) is described that features sequential conjugate addition and enolate arylation reactions to construct the tricyclic core in two steps.
DeLorbe
John E
JE
Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
Lotz
Monica D
MD
Martin
Stephen F
SF
D018360:Crystallography, X-Ray; D032502:Lycopodium / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D012717:Sesquiterpenes; C520065:lycopladine A