[Evaluation of biological activity of a dermatological preparation with elaeagnus angustifolia flowers soft extract].
It was elaborated a dermatological preparation with 6% g Elaeagnus angustifolia flowers soft extract incorporated in water washable cream base.


METHODS
The soft extract contents resins with a wound healing activity, flavones and polyphenols with antioxidant activity. This extract was standardized in flavones (0.965-1.465%) and polyphenols (1.076-1.348%).


RESULTS
The dermatological preparation has a low antioxidant activity (AA% = 25.7%), half of soft extract antioxidant activity (AA% = 45.9%), tested by chemiluminescence method. The wound healing effect of the dermatological preparation was tested on rabbit scarred skin.


CONCLUSIONS
The dermatological preparation had a superior activity than a control untreated or treated with washable cream base.
Bucur
Laura
L
Disciplina Farmacognozie, Universitatea Ovidius Constantă, Facultatea de Medicină Dentară si Farmacie.
Tarălungă
Gh
G
Alexandrescu
Rodica
R
Negreanu
Ticuţa
T
Istudor
Viorica
V
D000279:Administration, Cutaneous; D000818:Animals; D003879:Dermatologic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004195:Disease Models, Animal; D031263:Elaeagnaceae; D035264:Flowers; D009824:Ointments / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D011817:Rabbits; D016896:Treatment Outcome; D014945:Wound Healing; D014947:Wounds and Injuries / Q000188:drug therapy*
D003879:Dermatologic Agents; D009824:Ointments; D010936:Plant Extracts