title: Surgical treatment of dysplasia fibrosa and defectus fibrosus with bone allografts.
abstract: BACKGROUND
  A common feature of dysplasia fibrosa and defectus fibrosus is the development of foci of disordered fibrous tissue in bone that tend to grow and displace regular bone tissue. The objective of this study was to evaluate the efficacy of surgical treatment with bone allografts in patients with fibrous dysplasia and fibrous defect of bone.
  
  
  METHODS
  The study group consisted of 99 patients aged from 9 to 58 years (mean age 22 years), including 56 men and 43 women. A total of 145 surgical procedures were performed in this group at the Bone Tumour and Neoplasm Unit between 1999 and 2005. In all cases histopathological verification confirmed fibrous dysplasia or fibrous defect of bone. The follow-up period was from 1 to 5 years (mean 2.5 years).
  
  
  RESULTS
  In 85 patients there were no recurrences. A total of 96 surgical procedures were performed in this group. The other 14 patients experienced recurrences and no graft remodelling. Forty-nine surgical procedures were performed in this group because of multiple (from 2 to 6) relapses of the tumours.
  
  
  CONCLUSIONS
  1. Resection surgery and filling the defect with bone graft in the basic tyep of treatment in fibrous dysplasia and bibrous defect of bone and leads to good outcomes. 2. Frozen cortico-cancelleous allografts are well incorporated and bone remodeling is not assocaited with inflammatory complications, resulting into good outcomes of the operative treatment.
authors.affiliation: Dr J. Daab Regional Hospital of Trauma Surgery, Piekary Slaskie. oltom@onet.eu
authors.forename: Patryk
authors.initials: P
authors.lastname: Tomasik
authors.forename: Jerzy
authors.initials: J
authors.lastname: Spindel
authors.forename: Leszek
authors.initials: L
authors.lastname: Miszczyk
authors.forename: Adam
authors.initials: A
authors.lastname: Chrobok
authors.forename: Bogdan
authors.initials: B
authors.lastname: Koczy
authors.forename: Jerzy
authors.initials: J
authors.lastname: Widuchowski
authors.forename: Tomasz
authors.initials: T
authors.lastname: Mrozek
authors.forename: Jacek
authors.initials: J
authors.lastname: Matysiakiewicz
authors.forename: Bolesław
authors.initials: B
authors.lastname: Pilecki
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000150:complications / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D002648:Child; D005260:Female; D005354:Fibrosarcoma / Q000150:complications / Q000601:surgery*; D005357:Fibrous Dysplasia of Bone / Q000209:etiology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010016:Osteoma / Q000150:complications / Q000601:surgery*; D011044:Poland; D012008:Recurrence; D014184:Transplantation, Homologous; D055815:Young Adult