title: Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes.
abstract: Transketolase mutants previously identified for use with the non-phosphorylated aldehyde propanal have been explored with a series of linear and cyclic aliphatic aldehydes, and excellent stereoselectivities observed.
authors.affiliation: Department of Chemistry, University College London, 20 Gordon Street, London, UK WC1H 0AJ.
authors.forename: Armando
authors.initials: A
authors.lastname: Cázares
authors.forename: James L
authors.initials: JL
authors.lastname: Galman
authors.forename: Lydia G
authors.initials: LG
authors.lastname: Crago
authors.forename: Mark E B
authors.initials: ME
authors.lastname: Smith
authors.forename: John
authors.initials: J
authors.lastname: Strafford
authors.forename: Leonardo
authors.initials: L
authors.lastname: Ríos-Solís
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Lye
authors.forename: Paul A
authors.initials: PA
authors.lastname: Dalby
authors.forename: Helen C
authors.initials: HC
authors.lastname: Hailes
mesh_terms: D000447:Aldehydes / Q000737:chemistry* / Q000378:metabolism*; D020134:Catalytic Domain; D004926:Escherichia coli / Q000201:enzymology; D006900:Hydroxylation; D008958:Models, Molecular; D017354:Point Mutation; D013237:Stereoisomerism; D013379:Substrate Specificity; D014174:Transketolase / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*
chemical_list: D000447:Aldehydes; D014174:Transketolase