title: Suicide attempts after subthalamic nucleus stimulation for Parkinson's disease.
abstract: A higher risk of suicidal attempt after subthalamic nucleus deep brain stimulation (STN-DBS) for Parkinson's disease (PD) has been consistently reported. We retrospectively analyzed 3 PD patients with suicide attempts after STN-DBS. All patients had normal pre- and immediate postoperative psychopathological and cognitive evaluations, with STN-DBS yielding a good motor benefit. Levodopa medication was markedly reduced. Albeit there was a significant reduction in dopaminergic medication, there was also a considerable time lag to suicide attempt. Impulsive behavior could have played a higher role, going unnoticed in punctual psychopathological examinations. STN-DBS patients need a closer postoperative psychiatric and behavioral follow-up.
authors.affiliation: Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Rodrigues
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Rosas
authors.forename: Miguel F
authors.initials: MF
authors.lastname: Gago
authors.forename: Cláudia
authors.initials: C
authors.lastname: Sousa
authors.forename: Rosália
authors.initials: R
authors.lastname: Fonseca
authors.forename: Paulo
authors.initials: P
authors.lastname: Linhares
authors.forename: Margarida A
authors.initials: MA
authors.lastname: Basto
authors.forename: Graça
authors.initials: G
authors.lastname: Sousa
authors.forename: Carolina
authors.initials: C
authors.lastname: Garrett
authors.forename: Rui
authors.initials: R
authors.lastname: Vaz
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D046690:Deep Brain Stimulation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000523:psychology* / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000502:physiology*; D013405:Suicide / Q000523:psychology*
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa