title: [Calvarial reconstruction by customized bioactive implant].
abstract: Osseous craniofacial defects are commonly seen problems after operative treatment of craniosynostoses. This case report describes a calvarial reconstruction by means of computer-aided fabrication of a customised implant. Three-dimensional imaging is followed by computer-aided design and fabrication of a medical grade PCL-TCP biodegradable scaffold using the rapid prototyping technology fused deposition modelling (CAD/CAM). After six months the implant was well integrated, no defect area could be palpated any more and a beginning bony consolidation could be detected via CT.
authors.affiliation: Klinik für Mund-, Kiefer- und Gesichtschirurgie, Ludwig-Maximilians-Universität, Lindwurm Strasse 2a, Munich. Florian.Probst@med.uni-muenchen.de
authors.forename: F A
authors.initials: FA
authors.lastname: Probst
authors.forename: D W
authors.initials: DW
authors.lastname: Hutmacher
authors.forename: D F
authors.initials: DF
authors.lastname: Müller
authors.forename: H-G
authors.initials: HG
authors.lastname: Machens
authors.forename: J-T
authors.initials: JT
authors.lastname: Schantz
mesh_terms: D016025:Bone Transplantation / Q000379:methods*; D002130:Calcium Phosphates; D002648:Child; D017076:Computer-Aided Design; D003398:Craniosynostoses / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D011091:Polyesters; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery; D011474:Prosthesis Design; D019651:Plastic Surgery Procedures / Q000379:methods*; D012086:Reoperation; D012886:Skull / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D002130:Calcium Phosphates; D011091:Polyesters; C016240:polycaprolactone; C018392:tricalcium phosphate