Severe intellectual disability does not preclude renal transplantation.
BACKGROUND
Intellectual disability (ID) in patients with chronic kidney disease is a relative contraindication for kidney transplantation.


METHODS
We analysed a retrospective cohort of 16 recipients of kidney transplantation with ID and 83 controls.


RESULTS
Graft survival at 5 years was similar between patients (81.2%) and controls (80.2%), P = 0.9. Patient survival at 5 years was lower among patients (81.2% versus 94.4%, P < 0.05). Patients had more infection episodes, but no risk factors were identified.


CONCLUSIONS
Although recipients with ID have lower long-term patient survival, the equivalent graft survival rates support the indication of renal transplantation in such disability.
Galante
Nelson Z
NZ
Hospital do Rim e Hipertensão, Department of Medicine, Division of Nephrology, Federal University of São Paulo, Rua Borges Lagoa 960, Villa Clementino, São Paulo - SP, Brazil.
Dib
Gustavo A
GA
Medina-Pestana
José O
JO
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D015331:Cohort Studies; D000075202:Contraindications; D005260:Female; D006085:Graft Survival; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D053208:Kaplan-Meier Estimate; D007674:Kidney Diseases / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D012189:Retrospective Studies; D012720:Severity of Illness Index; D055815:Young Adult