title: Evaluations of laparoscopic proctocolectomy versus traditional technique in patients with rectal cancer.
abstract: BACKGROUND
  This was a retrospective study that evaluated the surgical outcomes of laparoscopic surgery (LS) for rectal cancer, in comparison with a case control series of open surgery (OS), during an 8-year period.
  
  
  METHODS
  Between October 1998 and December 2006, 203 patients with rectal malignancies underwent colectomy; 146 of them had colectomy with the traditional technique (OS), while 57 underwent resection of rectal cancer laparoscopically (LS). The LS group was compared with 60 patients from the OS group (selected from the 146 OS group patients), matched by size, sex, age, anatomical location of the tumor, type, extent of resection, and pathological stage. Data were obtained from patients' medical records. Statistical analysis was performed with the t test and chi-square test. All data are expressed as mean +/- standard error of the mean (SEM).
  
  
  RESULTS
  Mean age of the LS group was 63.7+/-12 years versus 69+/-12 years in the OS group. There were more men than women in both the laparoscopic (33 males, 24 females) and OS groups (35 men, 25 women). The mean follow-up period was 38 months and 78 months for LS and OS groups, respectively. The procedure included low anterior resection (43 in LS and 45 in OS), and 13 patients in both groups underwent abdominoperineal resection and 3 transanal resections (2 in OS and 1 in LS). Mean tumor size was 4.2+/-2.12cm in the LS versus 5.2+/-2.02cm in the OS group. Conversion to an open procedure occurred in 4 patients (6.7%), all in the first 20 cases. Postoperative complications developed in 28 patients (11.7%), 13 in the LS group and 15 in the OS group. Median operative time was longer, but median blood loss was significantly lower in the LS group. The length of hospital stay was significantly shorter for the LS group.
  
  
  CONCLUSIONS
  Laparoscopic surgery is feasible and safe for patients with rectal cancer and provides benefits during the postoperative period without increased morbidity or mortality.
authors.affiliation: Department of General Surgery, "G. Hatzikosta" General Hospital, Ioannina, Greece. skoulas@freemail.gr
authors.forename: Spyridon G
authors.initials: SG
authors.lastname: Koulas
authors.forename: George
authors.initials: G
authors.lastname: Pappas-Gogos
authors.forename: Spyridon
authors.initials: S
authors.lastname: Spirou
authors.forename: Evangelos
authors.initials: E
authors.lastname: Roustanis
authors.forename: Konstantinos E
authors.initials: KE
authors.lastname: Tsimogiannis
authors.forename: Georgios
authors.initials: G
authors.lastname: Tsirves
authors.forename: Evangelos C
authors.initials: EC
authors.lastname: Tsimoyiannis
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay / Q000706:statistics & numerical data; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011183:Postoperative Complications; D016737:Proctocolectomy, Restorative / Q000379:methods*; D016016:Proportional Hazards Models; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome