Acute eosinophilic myocarditis: diagnosis and treatment.
Hypereosinophilic syndrome (HES) is a rare disorder of unregulated eosinophilia, which if untreated, may lead to systemic tissue infiltration and inflammation. Cardiac involvement is a common and serious associated complication. We describe a case of HES associated myocarditis mimicking a non-ST elevation MI (NSTEMI). Unlike myocarditis in general, our patient responded well to high dose methylprednisone, the standard of care in HES. We review the clinical presentation, pathophysiology, pathology and treatment of eosinophilic myocarditis related to HES.
Rezaizadeh
Houman
H
New Jersey Medical School, Newark, NJ 07101, USA.
Sanchez-Ross
Monica
M
Kaluski
Edo
E
Klapholz
Marc
M
Haider
Bunyad
B
Gerula
Christine
C
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D018771:Arthralgia / Q000209:etiology; D001706:Biopsy; D002637:Chest Pain / Q000209:etiology; D003402:Creatine Kinase / Q000097:blood; D003937:Diagnosis, Differential; D004030:Dientamoebiasis / Q000150:complications / Q000188:drug therapy; D004562:Electrocardiography; D004804:Eosinophils; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D007958:Leukocyte Count; D008775:Methylprednisolone / Q000627:therapeutic use; D009205:Myocarditis / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood
D000893:Anti-Inflammatory Agents; D019210:Troponin I; D003402:Creatine Kinase; D008775:Methylprednisolone