title: Ewing's sarcoma with metachronous pulmonary metastasis after successful treatment of osteosarcoma in a child.
abstract: A rare case of duplicate tumor, osteosarcoma and Ewing's sarcoma, complicated by metachronous pulmonary metastasis in a child is reported. A nine-year-old girl's osteosarcoma was treated by neoadjuvant chemotherapy followed by surgery and adjuvant chemotherapy. Four years later, resection of the chest wall to remove an Ewing's sarcoma had to be performed, followed by chemotherapy and radiotherapy. At the age of 17, the girl underwent a metastasectomy of Ewing's sarcoma metastasis to the lung. Five years later, the patient is free from any recognizable malignant disease. We conclude that after the complete surgical removal of two primary tumors, metastasectomy is an optimal treatment procedure in case of a solitary pulmonary metastasis.
authors.affiliation: Second Department of Surgery, Faculty of Medicine, PJ Safarik University and L Pasteur Teaching Hospital, Kosice, Slovakia. m.stebnicky@gmail.com
authors.forename: Milan
authors.initials: M
authors.lastname: Stebnicky
authors.forename: Jozef
authors.initials: J
authors.lastname: Belak
authors.forename: Peter
authors.initials: P
authors.lastname: Bohus
authors.forename: Frantisek
authors.initials: F
authors.lastname: Gmitter
authors.forename: Igor
authors.initials: I
authors.lastname: Jenco
authors.forename: Ruzena
authors.initials: R
authors.lastname: Tkacova
mesh_terms: D000293:Adolescent; D000671:Amputation, Surgical; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002648:Child; D005260:Female; D005266:Femoral Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D020360:Neoadjuvant Therapy / Q000379:methods; D016609:Neoplasms, Second Primary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D012516:Osteosarcoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D018714:Radiotherapy, Adjuvant; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D035441:Thoracic Wall; D013908:Thoracotomy; D016896:Treatment Outcome