title: Salivary anti-Helicobacter pylori positivity among endoscopy patients with chronic liver disease.
abstract: In this study, endoscopy patients with and without chronic liver disease (CLD) were examined and tested for Helicobacter pylori infection by detecting the presence of serum and salivary anti-H. pylori antibody. The validity of these measures was compared with Campylobacter-like organism analysis (gold standard) performed on patients requiring gastric biopsy. Among 114 patients with CLD and 50 without, the commonest endoscopy diagnosis was gastritis (27.2%). Salivary H. pylori positivity was significantly associated with older age. Salivary anti-H. pylori antibody positivity showed low sensitivity (36.6%) and high specificity (75.8%) in CLD patients.
authors.affiliation: Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: R
authors.initials: R
authors.lastname: Feteih
authors.forename: M
authors.initials: M
authors.lastname: Abdel-Salam
authors.forename: H
authors.initials: H
authors.lastname: Jamjoom
authors.forename: H
authors.initials: H
authors.lastname: Akbar
mesh_terms: D017677:Age Distribution; D000907:Antibodies, Bacterial / Q000032:analysis / Q000097:blood; D001706:Biopsy; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000209:etiology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D012463:Saliva / Q000276:immunology*; D012529:Saudi Arabia / Q000453:epidemiology; D012680:Sensitivity and Specificity
chemical_list: D000907:Antibodies, Bacterial