title: Banded collagen in the kidney with special reference to collagenofibrotic glomerulopathy.
abstract: BACKGROUND
  The normal glomerular basement membrane, composed of type IV collagen, plays an important function in the process of filtration. Rarely, type III, type I, or type V collagen is seen in the glomerulus, resulting in three different types of non-immune mediated glomerulopathies recognized thus far. These are characterized by deposition of banded collagen fibers in the glomerulus.
  
  
  METHODS
  The authors reviewed 4934 kidney biopsies submitted over the past 5 years. Five of these revealed the presence of banded collagen in the glomeruli.
  
  
  CONCLUSIONS
  Combined clinical and ultrastructural examination has led to a definitive diagnosis. These diseases exhibit indolent progression and as yet do not have specific treatment.
authors.affiliation: Jaslok Hospital & Research Center, Bhatia Hospital, Mumbai, India. shailakhubchandani@yahoo.co.in
authors.forename: Shaila R
authors.initials: SR
authors.lastname: Khubchandani
authors.forename: Arun R
authors.initials: AR
authors.lastname: Chitale
authors.forename: Swarnalata
authors.initials: S
authors.lastname: Gowrishankar
mesh_terms: D000328:Adult; D001706:Biopsy; D002648:Child; D024141:Collagen Type IV / Q000378:metabolism / Q000648:ultrastructure*; D005260:Female; D050533:Glomerular Basement Membrane / Q000378:metabolism / Q000648:ultrastructure*; D005920:Glomerular Mesangium / Q000648:ultrastructure; D005921:Glomerulonephritis / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007668:Kidney; D008297:Male; D009261:Nail-Patella Syndrome / Q000378:metabolism / Q000473:pathology; D055815:Young Adult
chemical_list: D024141:Collagen Type IV