Long-term immunity after two doses of inactivated hepatitis A vaccine, in Argentinean children.
We examined long-term anti-hepatitis A virus antibody persistence in Argentinean children 10 years after the initial study in which they received 2 doses of inactivated hepatitis A vaccine (Avaxim 80U). Of the 111 children, 48 from the initial trial were enrolled. Of 48, 47 (97.9%) participants had serum anti-hepatitis A virus antibody titers > or =20 mIU/mL, with the geometric mean concentration of 390.91 (+/-370.14) mIU/mL; (95% confidence interval, 282.2-499.5 mIU/mL), range, 36 to 1860.
López
Eduardo L
EL
Infectious Diseases Program, Hospital de Niños Dr. Ricardo Gutiérrez, Buenos Aires, Argentina. eduardoluislopez@fibertel.com.ar
Contrini
María M
MM
Mistchenko
Alicia
A
Debbag
Roberto
R
D000293:Adolescent; D001118:Argentina / Q000453:epidemiology; D016009:Chi-Square Distribution; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006506:Hepatitis A / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D035922:Hepatitis A Antibodies / Q000097:blood; D022362:Hepatitis A Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D008297:Male; D018709:Statistics, Nonparametric; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology
D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines; D015164:Vaccines, Inactivated