title: Cutaneous macroglobulinosis deposits in a patient with IgM paraproteinemia/incipient Waldenström macroglobulinemia.
abstract: A 43-year-old healthy patient developed disseminated flat skin-colored to red-brown papules over a few months. These papules were the result of cutaneous IgM deposits representing the first symptom of a hitherto undiagnosed IgM paraproteinemia. This extremely rare skin manifestation of IgM paraproteinemia e. g. possibly incipient Waldenström macroglobulinemia should be included in the histopathological differential of eosinophilic dermal deposits.
authors.affiliation: Dermatohistopathological Laboratory, Munich, Germany. lueftl@derma-muenchner-freiheit.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Lüftl
authors.forename: Birthe
authors.initials: B
authors.lastname: Sauter-Jenne
authors.forename: Martin
authors.initials: M
authors.lastname: Gramatzki
authors.forename: Fritjof
authors.initials: F
authors.lastname: Eckert
authors.forename: Lars
authors.initials: L
authors.lastname: Jenne
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D008259:Macroglobulins; D008297:Male; D010265:Paraproteinemias / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D011694:Purpura, Hyperglobulinemic / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D007075:Immunoglobulin M; D008259:Macroglobulins