Sensory neuronopathy with Ro antibodies: response to combination immunosuppression.
The objective of this study was to describe a case of sensory neuronopathy syndrome (SNS) with Ro antibodies who had nearly complete functional recovery with combination immunosuppression. Plasma exchange, azathioprine, and hydroxychloroquine were used in combination. The gait ataxia, kinesthetic sensation, and sensory response amplitudes showed considerable recovery with excellent functional outcomes. Prompt combined therapy with azathioprine and hydroxychloroquine is a promising therapy for patients with sensory neuronopathy syndrome and Ro antibodies.
Hussain
Aamir
A
Beth Israel Medical Center, New York, NY, USA.
Scelsa
Stephen N
SN
D000906:Antibodies / Q000008:administration & dosage*; D000974:Antibodies, Antinuclear / Q000276:immunology / Q000378:metabolism*; D004359:Drug Therapy, Combination / Q000379:methods; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D020422:Mononeuropathies / Q000276:immunology* / Q000628:therapy*; D055815:Young Adult
D000906:Antibodies; D000974:Antibodies, Antinuclear; D007166:Immunosuppressive Agents; C035356:SS-A antibodies