Previews. Niche today, gone tomorrow--progenitors create short-lived niche for stem cell specification.
Establishing tissue-specific adult stem cells during organogenesis is important for maintenance of tissue homeostasis throughout the lifetime of the organism. In a recent study in Science, Mathur et al. (2010) describe how progenitor cells in the Drosophila larval midgut create a temporary niche to maintain stem cell fate during development.
Issigonis
Melanie
M
Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Matunis
Erika
E