title: 7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin.
abstract: Carbonyl ylide cycloaddition strategy was employed in the synthesis of platensimycin analogs. 7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin are more potent analogs of platensimycin.
authors.affiliation: Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Republic of Korea.
authors.forename: Ki Po
authors.initials: KP
authors.lastname: Jang
authors.forename: Chan Hyuk
authors.initials: CH
authors.lastname: Kim
authors.forename: Seong Wook
authors.initials: SW
authors.lastname: Na
authors.forename: Dong Seok
authors.initials: DS
authors.lastname: Jang
authors.forename: Hiyoung
authors.initials: H
authors.lastname: Kim
authors.forename: Heonjoong
authors.initials: H
authors.lastname: Kang
authors.forename: Eun
authors.initials: E
authors.lastname: Lee
mesh_terms: D000218:Adamantane / Q000737:chemistry* / Q000494:pharmacology*; D062365:Aminobenzoates / Q000737:chemistry* / Q000494:pharmacology*; D000813:Anilides / Q000737:chemistry* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D016983:Enterococcus / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D062365:Aminobenzoates; D000813:Anilides; D000900:Anti-Bacterial Agents; D000218:Adamantane; C510909:platensimycin