Genomic characterization of a proventriculitis-associated infectious bronchitis coronavirus.
Transmissible proventriculitis associated with infectious bronchitis virus (IBV) was at first seen in eastern China in mid-1995, and is now endemic in China. Herein, the complete genome sequence of a proventiculitis-associated infectious bronchitis coronavirus (ZJ971) was sequenced and analyzed. Compared with the genome of the vaccine strain H120, ZJ971 had 54 nucleotide substitutions and a deletion in the 3'-UTR. The substitutions were in the regions of nsp2-nsp5, nsp7, nsp12, nsp13, nsp15, S and N genes, and the untranslating region. The results indicated that ZJ971 could be a variant of IBV strain H120.
Xiao
Chao-ting
CT
Key Laboratory of Animal Epidemic Etiology & Immunological Prevention of Ministry of Agriculture, Zhejiang University, Hangzhou 310029, People's Republic of China.
Liu
Ran
R
Song
Zhu-yuan
ZY
Liao
Min
M
Zhou
Ji-yong
JY
D020413:3' Untranslated Regions; D000818:Animals; D002681:China / Q000453:epidemiology; D018352:Coronavirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D016679:Genome, Viral; D001351:Infectious bronchitis virus / Q000235:genetics* / Q000302:isolation & purification*; D017354:Point Mutation; D011531:Proventriculus / Q000473:pathology / Q000821:virology*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D013272:Stomach Diseases / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D014764:Viral Proteins / Q000235:genetics
D020413:3' Untranslated Regions; D014764:Viral Proteins