Dynamics of clinical symptoms in patients with pandemic influenza A (H1N1).
We evaluated the dynamics of clinical symptoms of 2009 pandemic influenza A (H1N1) using a four-point scale sheet. The most frequent symptoms were fever and cough. The sum of symptom score was high during the first 4 days. Systemic symptoms peaked earlier, by day 2, and resolved faster than upper respiratory symptoms and lower respiratory symptoms after oseltamivir treatment. The lower respiratory symptoms resolved slowly over 2 weeks. The 2009 pandemic influenza A (H1N1) virus might involve primarily lower respiratory tract and could be the main cause of pneumonia.
Lee
C-S
CS
Internal Medicine, Chonbuk National University Medical School, Jeonju, South Korea. lcsmd@jbnu.ac.kr
Lee
J-H
JH
D003371:Cough / Q000453:epidemiology; D004196:Disease Outbreaks; D005334:Fever / Q000453:epidemiology; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000175:diagnosis* / Q000453:epidemiology; D010612:Pharyngitis / Q000453:epidemiology; D011024:Pneumonia, Viral / Q000209:etiology