title: [Endometrial osseous metaplasia: clinical presentation and follow-up].
abstract: OBJECTIVE
  to describe the clinical signs and symptoms of patients with bone metaplasia and to assess the risk factors for changes in these symptoms after removal of the bone fragment.
  
  
  METHODS
  a cross-sectional study was conducted on 16 patients with a diagnosis of bone fragments in the uterine cavity during the period comprising July 2006 to January 2009. The inclusion criterion was the detection of a bone fragment removed from the uterine cavity. The presence of bone tissue in the endometrial cavity was histologically confirmed in all patients. The data of all patients were obtained before and after removal by means of a questionnaire for the evaluation of the effect of removal on the symptoms and for the search of possible factors related to the onset of the disease.
  
  
  RESULTS
  half the patients (8/16) had hemorrhagic symptoms and one third (6/16) were infertile. Removal of the fragments was quite effective in improving the complaints, with the disappearance of symptoms in all cases of hemorrhage and of pelvic pain.
  
  
  CONCLUSIONS
  removal of bone fragments can restore the fertility of selected patients whose infertility is caused by bone metaplasia and is quite effective in leading to improvement in patients with pelvic pain and menorrhage.
authors.affiliation: Ginecologista do Ministério da Saúde e da Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ), Brasil. raphaelcmparente@hotmail.com
authors.forename: Raphael Câmara Medeiros
authors.initials: RC
authors.lastname: Parente
authors.forename: Vilmon
authors.initials: V
authors.lastname: de Freitas
authors.forename: Rodrigo Soares
authors.initials: RS
authors.lastname: de Moura Neto
authors.forename: Marco Aurélio Pinho
authors.initials: MA
authors.lastname: de Oliveira
authors.forename: Ricardo Bassil
authors.initials: RB
authors.lastname: Lasmar
authors.forename: Marisa Teresinha
authors.initials: MT
authors.lastname: Patriarca
authors.forename: Felipe Simões
authors.initials: FS
authors.lastname: Canavez
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008679:Metaplasia; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000175:diagnosis / Q000601:surgery; D014591:Uterine Diseases / Q000175:diagnosis / Q000601:surgery; D055815:Young Adult