[Food intake and colorectal cancers; an ecological study in Romania].
The aim of the present study performed in a Romanian population was to identify the food which can be either associated with or protect against colorectal carcinoma.


METHODS
Correlation and regression analysis were used to examine the association between dietary intake and the rate of incidence for colon, rectum and anus cancers, in study groups from 7 regions of Romania.


RESULTS
A strong and positive association was observed for colonic cancer and the intake of coffee, tea and cocoa (r = 0.77, p = 0.042) whereas statistical significance of borderline value was found for margarine (r = 0.73, p = 0.06) and sweets (r = 0.74, p = 0.066) intake. A potential protective effect can be attributed to wine consumption ( r = -0.75, p = 0.03). The malignancies of the rectum and anus showed both a strong positive correlation with the intake of red meat ( r = 0.76, p = 0.048), sausages ( r = 0.87, p = 0.012), margarine (r = 0.97, p = 0.0004), butter ( r = 0.76, p = 0.049), sweets ( r = 0.93, p = 0.003), beverages (r = 0.97, p = 0.0003), coffee, tea, cocoa ( r = 0.94, p = 0.002). Negative correlations were reported for the recto-anal cancer and the consumption of: fish (r = -0.8, p = 0.032), cheese (r = -0.9, p = 0.006), wine (r = -0.85, p = 0.015).


CONCLUSIONS
The need for reducing the dietary intake of margarine, red meat, sausages and sweets while the beneficial effects of wine consumption have been also confirmed.
Fira-Mladinescu
Corneluţa
C
Centrul de Studii in Medicină Preventivă, Universitatea de Medicină si Farmacie "V. Babeş" Timişõara.
Fira-Mladinescu
O
O
Doroftei
Sorina
S
Sas
Felicia
F
Ursoniu
S
S
Ionuţ
R
R
Putnoky
Salomeia
S
Suciu
Oana
O
Vlaicu
Brigitha
B
D000465:Algorithms; D000704:Analysis of Variance; D002241:Carbohydrates / Q000009:adverse effects; D002277:Carcinoma / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control; D003069:Coffee / Q000009:adverse effects; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control; D003611:Dairy Products / Q000706:statistics & numerical data; D004034:Diet Surveys; D004041:Dietary Fats / Q000009:adverse effects; D004435:Eating; D002523:Edible Grain; D005247:Feeding Behavior; D005396:Fish Products / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008383:Margarine / Q000009:adverse effects; D008460:Meat / Q000009:adverse effects / Q000706:statistics & numerical data; D008461:Meat Products / Q000009:adverse effects / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D011795:Surveys and Questionnaires; D013662:Tea / Q000009:adverse effects; D014675:Vegetables; D014920:Wine / Q000706:statistics & numerical data
D002241:Carbohydrates; D003069:Coffee; D004041:Dietary Fats; D013662:Tea; D008383:Margarine