[Identification of HBV genotype-specific tag sequences].
OBJECTIVE
To identify the HBV genotype-specific tag sequence.


METHODS
The large S region sequences from 930 HBV genomes were aligned to identify the genotype-specific tag sequences. PCR was used to check the genotyping effect of these tags.


RESULTS
Two tag sequences, sequence between 149-169 and sequence between 461-483, were identified in the large S region. Using primers specific to these tag sequences, the genotype of HBV can be specifically identified.


CONCLUSIONS
These tag sequences can be used for HBV genotyping.
Cai
Ying
Y
Department of Infectious Diseases, No.324 Hospital of PLA, Chongqing 400020, China.
Li
Xue-cheng
XC
Wu
Xiao-mei
XM
Wang
Ning
N
Cao
Hong-wei
HW
Wei
Guo
G
Zhao
Ke-cen
KC
Zheng
Kai
K
Zheng
Jiang
J
Li
Yan
Y
D001483:Base Sequence; D017931:DNA Primers; D015723:Gene Library; D005814:Genes, Viral; D005838:Genotype; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics*; D019694:Hepatitis B, Chronic / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods*; D011498:Protein Precursors / Q000235:genetics; D017422:Sequence Analysis, DNA
D017931:DNA Primers; D011498:Protein Precursors