title: A new powerful strategy for the organocatalytic asymmetric construction of a quaternary carbon stereogenic center.
abstract: A new method for chiral diamine-catalyzed Robinson-type annulation was developed to construct cyclohexenone derivatives bearing a quaternary carbon stereogenic center at the 4-position in high enantiomeric excess. This method was successfully applied to the short synthesis of (+)-sporochnol A.
authors.affiliation: Laboratory of Natural Product Chemistry, Faculty of Science, Kochi University, Akebono-cho, Kochi 780-8520, Japan.
authors.forename: Yogo
authors.initials: Y
authors.lastname: Inokoishi
authors.forename: Niiha
authors.initials: N
authors.lastname: Sasakura
authors.forename: Keiji
authors.initials: K
authors.lastname: Nakano
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Hiyoshizo
authors.initials: H
authors.lastname: Kotsuki
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003512:Cyclohexanones / Q000138:chemical synthesis* / Q000737:chemistry; D003959:Diamines / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D003512:Cyclohexanones; D003959:Diamines; D010636:Phenols; C445786:sporochnol A; D002244:Carbon