title: Rigid hydrophilic structures for improved properties of conjugated polymers and nitrotyrosine sensing in water.
abstract: The efficient synthesis of a hydrophilic monomer bearing a three-dimensional noncompliant array of hydroxyl groups is described that prevents water-driven excimer features of hydrophobic poly(p-phenylene ethynylene) backbones. Sensitivity of the polymer to 3-nitrotyrosine is also discussed.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: Brett
authors.initials: B
authors.lastname: VanVeller
authors.forename: Koji
authors.initials: K
authors.lastname: Miki
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Swager
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004987:Ethers / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D012995:Solubility; D013237:Stereoisomerism; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004987:Ethers; C436384:phenyleneethynylene; D014867:Water; C002744:3-nitrotyrosine; D014443:Tyrosine