Chikungunya virus infection during pregnancy, Reunion, France, 2006.
Mother-to-child transmission of chikungunya virus was reported during the 2005-2006 outbreak on Reunion Island, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Reunion in 2006. The study population was composed of 1,400 pregnant women (628 uninfected, 658 infected during pregnancy, 27 infected before pregnancy, and 87 infected on unknown dates). We compared pregnancy outcomes for 655 (628 + 27) women not infected during pregnancy with 658 who were infected during pregnancy. Infection occurred during the first trimester for 15% of the infected women, the second for 59%, and the third for 26%. Only hospital admission during pregnancy differed between infected and uninfected women (40% vs. 29%). Other outcomes (cesarean deliveries, obstetric hemorrhaging, preterm births, stillbirths after 22 weeks, birthweight, congenital malformations, and newborn admissions) were similar. This virus had no observable effect on pregnancy outcomes.
Fritel
Xavier
X
Centre Hospitalier Régional de la Réunion, Saint-Denis, France.
Rollot
Olivier
O
Gerardin
Patrick
P
Gauzere
Bernard Alex
BA
Bideault
Jacques
J
Lagarde
Louis
L
Dhuime
Barbara
B
Orvain
Eric
E
Cuillier
Fabrice
F
Ramful
Duksha
D
Samperiz
Sylvain
S
Jaffar-Bandjee
Marie Christine
MC
Michault
Alain
A
Cotte
Liliane
L
Kaminski
Monique
M
Fourmaintraux
Alain
A
D018354:Alphavirus Infections / Q000453:epidemiology* / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood; D002646:Chikungunya virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004196:Disease Outbreaks; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000821:virology; D011256:Pregnancy Outcome; D011264:Pregnancy Trimesters; D011446:Prospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction
D000914:Antibodies, Viral