title: Coats' disease: an Indian perspective.
abstract: OBJECTIVE
  To describe the clinical features, treatment and outcome patterns in 307 eyes with Coats' disease.
  
  
  METHODS
  Retrospective chart review of patients diagnosed with Coats' disease between January 1996 and January 2006 from a single referral center in southern India.
  
  
  RESULTS
  Two hundred and eighty patients (307 eyes) with mean age of 15.67 years (range: Four months-80 years) were included. Decreased vision (77%), unilateral affection (90%) and male preponderance (83.4%) were chief presenting features. Anterior segment involvement was seen in 67 (21.8%) eyes. Retinal telangiectasia were seen in 302 (99%) eyes, exudation in 274 (89%) eyes and retinal detachment in 158 (51.5%) eyes. Four-quadrant disease was seen in 207 (67.2%) eyes. Visual acuity was <20/200 in 249 (80.9%) eyes. One hundred and nine of 176 treated eyes (61.93%) had favorable anatomical outcome; 207 of 280 eyes (74%) had an optimal structural outcome. Seventeen (5.3%) eyes were enucleated. Complications following treatment included phthisis bulbi (7%), neovascular glaucoma (5%), epiretinal membrane (4.4%) and rubeosis iridis (4.4%).
  
  
  CONCLUSIONS
  Indian patients with Coats' disease have a high male predominance, the majority of whom present with severe visual impairment and extensive four-quadrant exudation. Unusual presentations such as pain, vitreous hemorrhage and a high incidence of anterior segment involvement are distinctive to Indian eyes.
authors.affiliation: Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai-600 006, India.
authors.forename: Pukhraj
authors.initials: P
authors.lastname: Rishi
authors.forename: Ekta
authors.initials: E
authors.lastname: Rishi
authors.forename: Mahesh
authors.initials: M
authors.lastname: Uparkar
authors.forename: Tarun
authors.initials: T
authors.lastname: Sharma
authors.forename: Lingam
authors.initials: L
authors.lastname: Gopal
authors.forename: Pramod
authors.initials: P
authors.lastname: Bhende
authors.forename: Muna
authors.initials: M
authors.lastname: Bhende
authors.forename: Pratik Ranjan
authors.initials: PR
authors.lastname: Sen
authors.forename: Parveen
authors.initials: P
authors.lastname: Sen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D055815:Young Adult