Does HIV-related cholangiopathy exist in the setting of liver transplantation?
Biliary tract complications after liver transplantation represent a source of morbidity and mortality. Performing an analysis to evaluate whether HIV infection and its related comorbidities, such as HIV-related cholangiopathy, could be an unknown risk factor for biliary stricture, we found that HIV-positivity could lead to greater susceptibility to biliary damage. The pathogenesis of the damage seems to involve the pretransplant immunological status and the number and type of posttransplant infections, although further studies are needed.
Spaggiari
Mario
M
Liver and Multivisceral Transplant Centre, University of Modena and Reggio Emilia, Modena, Italy.
Ballarin
Roberto
R
di Benedetto
Fabrizio
F
Montalti
Roberto
R
de Ruvo
Nicola
N
Cautero
Nicola
N
Guerrini
Giampiero
G
Gerunda
Giorgio E
GE
D000328:Adult; D015658:HIV Infections / Q000150:complications / Q000276:immunology* / Q000401:mortality; D006509:Hepatitis B / Q000276:immunology* / Q000401:mortality; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000276:immunology* / Q000401:mortality; D008297:Male; D011183:Postoperative Complications / Q000401:mortality; D012307:Risk Factors; D015996:Survival Rate