title: [Neuronal plasticity and gene expression].
abstract: Neuronal plasticity--a fundamental feature of brain--provides adequate interactions with dynamic environment. One of the most deeply investigated forms of the neuronal plasticity is a long-term potentiation (LTP)--a phenomenon underlying learning and memory. Signal paths activated during LTP converge into the nuclear of the neuron, giving rise to launch of the molecular-genetic programs, which mediate structural and functional remodeling of synapses. In the review data concerning involvement of multilevel gene expression into plastic change under neuronal activation are summarized.
authors.forename: O O
authors.initials: OO
authors.lastname: Sokolova
authors.forename: M B
authors.initials: MB
authors.lastname: Shtark
authors.forename: P D
authors.initials: PD
authors.lastname: Lisachev
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D002493:Central Nervous System Diseases / Q000235:genetics / Q000503:physiopathology; D015870:Gene Expression; D005786:Gene Expression Regulation; D006801:Humans; D007858:Learning / Q000502:physiology; D017774:Long-Term Potentiation; D008568:Memory / Q000502:physiology; D009473:Neuronal Plasticity / Q000235:genetics / Q000502:physiology*