title: Giant cell tumor of the sacrum treated with selective arterial embolization.
abstract: Giant cell tumor of the sacrum is extremely difficult to manage. Standard treatments, including surgery and radiation, are associated with significant complications and recurrence rates. In this manuscript, we report an early clinical result of a case of giant cell tumor of the sacrum successfully managed with selective arterial embolization. A 56-year-old woman underwent selective embolization for management of giant cell tumor of the sacrum. Radiologically, massive shrinkage of the extraosseous mass and increased peripheral ossification were obvious. Clinically, rapid pain relief was achieved and gait disability recovered. At final follow-up 28 months after completion of treatment, she retained normal activity in daily life. We stress the effectiveness of selective arterial embolization as a less invasive and less complicated primary treatment of giant cell tumors of the sacrum.
authors.affiliation: Department of Orthopedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16 Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Onishi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kaya
authors.forename: Takuro
authors.initials: T
authors.lastname: Wada
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagoya
authors.forename: Mikito
authors.initials: M
authors.lastname: Sasaki
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Yamashita
mesh_terms: D000203:Activities of Daily Living; D001706:Biopsy; D004621:Embolization, Therapeutic; D005260:Female; D005263:Femoral Artery; D018212:Giant Cell Tumor of Bone / Q000098:blood supply / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D017116:Low Back Pain / Q000209:etiology / Q000517:prevention & control; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020127:Recovery of Function; D012447:Sacrum / Q000000981:diagnostic imaging / Q000473:pathology; D013125:Spinal Neoplasms / Q000098:blood supply / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome