title: [Early postoperative enteral immunocorrection using modified pectin containing drugs in peritonitis].
abstract: Surgical endotoxicosis entails dysfunction of all organs and systems including immune system that considerably aggravates severity of current disease and slows down a recovery in the postoperative period. Searching of various ways of immunocorrection in peritonitis of various etiology is the actual commitment of the contemporary surgery. The complex method of simultaneous enterosorbtion and immunocorrection with the modified pectin contained specimen in patients with a peritonitis is offered. In study the role natural enteral sorbents in optimization of the immune answer due to restoration of microbiocenosis sorbtion and immunocorrection modified with the modified pectin contained intestines is proved. Entero specimen provide decreasing of medium molecular weight substances' level to 89.0% in reactive stage of a peritonitis and to 69.0%--in toxic stage during 3 days. By 5th day of treatment the level of medium molecular weight substances and leucocyte intoxication index were already reached to the normal parameters. It allows us to recommend this introducted method in a complex of medical treatment in postoperation period in peritonitis.
authors.forename: D A
authors.initials: DA
authors.lastname: Demidov
authors.forename: M V
authors.initials: MV
authors.lastname: Kostiuchenko
authors.forename: M V
authors.initials: MV
authors.lastname: Meshkov
authors.forename: L A
authors.initials: LA
authors.lastname: Dudenko
mesh_terms: D000818:Animals; D000930:Antidiarrheals / Q000494:pharmacology*; D004750:Enteral Nutrition; D016061:Enterosorption / Q000379:methods*; D006801:Humans; D008297:Male; D010368:Pectins / Q000494:pharmacology*; D010538:Peritonitis / Q000209:etiology / Q000276:immunology* / Q000628:therapy*; D011182:Postoperative Care; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D000930:Antidiarrheals; D010368:Pectins