Immobilization of 3,5-dimethylphenylcarbamates of cellulose and amylose onto silica gel using (3-glycidoxypropyl)triethoxysilane as linker.
The 3,5-dimethylphenylcarbamates of cellulose and amylose were effectively immobilized onto plain silica gels as chiral packing materials (CPMs) for HPLC by means of intermolecular polycondensation of triethoxysilyl groups introduced with (3-glycidoxypropyl)triethoxysilane. The immobilization and chiral recognition abilities of the obtained CPMs prepared with different amounts of (3-glycidoxypropyl)triethoxysilane were investigated. In addition, the solvent compatibilities of the immobilized-type CPMs were examined with eluents containing chloroform and THF. When these eluents were used, for most of the tested racemates, the chiral resolving abilities of the obtained CPMs were improved.
Tang
Shouwan
S
Department of Chemistry, School of Pharmaceutical and Chemical Engineering, Taizhou College, Linhai, PR China. tsw1437@hotmail.com
Ikai
Tomoyuki
T
Tsuji
Masashi
M
Okamoto
Yoshio
Y
D000688:Amylose / Q000737:chemistry*; D002219:Carbamates / Q000737:chemistry*; D002482:Cellulose / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D012821:Silanes / Q000737:chemistry*; D058428:Silica Gel; D012822:Silicon Dioxide / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
C403136:3-glycidoxypropyltrimethoxysilane; D002219:Carbamates; D012821:Silanes; D058428:Silica Gel; D012822:Silicon Dioxide; D002482:Cellulose; D000688:Amylose