title: Motor function reorganization lateral to congenital brain lesion: a functional MRI study.
abstract: OBJECTIVE
  The object of this study was to demonstrate the reorganization of the affected hand motor function lateral to the congenital brain lesion in a patient using functional MRI (fMRI).
  
  
  METHODS
  Twelve normal control subjects and a 23-year-old man with a congenital brain lesion including the precentral knob were evaluated. FMRI was performed using the blood oxygen level-dependent technique at 1.5-T system with timed hand grasp-lease motor tasks.
  
  
  RESULTS
  The contralateral primary sensorimotor cortex centered on the precentral knob was activated during hand movements of the right side of the patient and of control subjects. However, only the lateral area of the lesion was activated during left hand movements of the patient.
  
  
  CONCLUSIONS
  It seems that the motor function of the left hand was reorganized into the lateral area of the lesion in this patient. This finding may reflect a cortical reorganization of the motor area.
authors.affiliation: Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea. strokerehab@hanmail.net
authors.forename: Su Min
authors.initials: SM
authors.lastname: Son
authors.forename: Yong-Hyun
authors.initials: YH
authors.lastname: Kwon
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jang
mesh_terms: D001921:Brain / Q000098:blood supply*; D001930:Brain Injuries / Q000473:pathology / Q000503:physiopathology; D000077463:Carbamide Peroxide; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009044:Motor Cortex / Q000098:blood supply* / Q000503:physiopathology; D009473:Neuronal Plasticity; D010545:Peroxides / Q000097:blood; D013003:Somatosensory Cortex / Q000098:blood supply* / Q000503:physiopathology; D014508:Urea / Q000031:analogs & derivatives / Q000097:blood; D055815:Young Adult
chemical_list: D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea