title: Antibiotic resistance trends in paediatric community-acquired first urinary tract infections in the United Arab Emirates.
abstract: We analysed the trend of antibiotic resistance of community-acquired uropathogens over a 4-year period in a cohort of children with a first episode of culture-proven urinary tract infection presenting to the department of paediatrics at a large general secondary care hospital in the United Arab Emirates. Comparisons were made between 2 time periods: 2003-04 versus 2005-06 for 145 children aged 2 months to 12 years of age. Although some changes in resistance were observed for some antibiotics between the 2 time periods, the differences were not significant, nor were the trends, except for a significant increase in resistance to nitrofurantoin (from 5.4% to 35.6%), with a significant increasing trend over the 4 years.
authors.affiliation: Department of Paediatrics, Faculty of Medicine and Health Sciences, Al Ain, United Arab Emirates. hassib.narchi@uaeu.ac.ae
authors.forename: H
authors.initials: H
authors.lastname: Narchi
authors.forename: M A M
authors.initials: MA
authors.lastname: Al-Hamdan
mesh_terms: D017668:Age of Onset; D000892:Anti-Infective Agents, Urinary; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006769:Hospitals, General; D006801:Humans; D007223:Infant; D007710:Klebsiella Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D008297:Male; D008826:Microbial Sensitivity Tests; D009582:Nitrofurantoin / Q000627:therapeutic use; D011159:Population Surveillance; D014479:United Arab Emirates / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000892:Anti-Infective Agents, Urinary; D009582:Nitrofurantoin