title: Evaluation of seven X-chromosomal short tandem repeat loci located within the Xq26 region.
abstract: In this study a set of 29 X-chromosomal short tandem repeats (STRs) located within the Xq26 region was evaluated. These STRs were found within the 133.14-133.45Mb region around the HPRTB locus. Evaluation of the microsatellites was performed with regard to polymorphism, reliable amplification, and low stutter artefacts. DXS10101, DXS10102, and DXS10103 were identified as those X-STRs with highest diversity; i.e. PIC values of 0.7174-0.8933. The locus DXS10101 was the optimal candidate for the integration in the commercial available test system Mentype Argus X-8 PCR amplification kit.
authors.affiliation: Biotype AG, Moritzburger Weg 67, 01109 Dresden, Germany.
authors.forename: Heike
authors.initials: H
authors.lastname: Rodig
authors.forename: Frank
authors.initials: F
authors.lastname: Kloep
authors.forename: Lydia
authors.initials: L
authors.lastname: Weissbach
authors.forename: Christa
authors.initials: C
authors.lastname: Augustin
authors.forename: Jeannett
authors.initials: J
authors.lastname: Edelmann
authors.forename: Sandra
authors.initials: S
authors.lastname: Hering
authors.forename: Reinhard
authors.initials: R
authors.lastname: Szibor
authors.forename: Frank
authors.initials: F
authors.lastname: Götz
authors.forename: Werner
authors.initials: W
authors.lastname: Brabetz
mesh_terms: D041321:Chromosomes, Human, X; D017931:DNA Primers; D004586:Electrophoresis; D006239:Haplotypes; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA; D020080:Tandem Repeat Sequences
chemical_list: D017931:DNA Primers