Mismatch Negativity (MMN) response studies in elderly subjects.
Mismatch Negativity is an endogenous potential which reflects the processing of differences incurred in the acoustic stimulus.


OBJECTIVE
to characterize MMN responses in elderly subjects and compare with adult subjects.


METHODS
prospective study involving 30 subjects, 15 men and 15 women, aged between 60 and 80 years and 11 months. Statistical test: Mann-Whitney. The subjects went through medical evaluation, threshold tonal audiometry, immittance tests, otoacoustic emissions and short and long latency auditory potentials (MMN).


RESULTS
mean latency was 161.33 ms (CZA2) and 148.67 ms (CZA1), in women; of 171 ms (CZA2) and 159.07 ms (CZA1), men. Mean amplitude was -2.753 microV (CZA2) and -2.177 microV (CZA1), women; -1.847 microV (CZA2) and -1.953 microV (CZA1), men. As to the right and left hemispheres, mean latency variable of 166 ms (CZA2) and 153.87 ms (CZA1); for the amplitude variable, mean value of -2.316 microV (CZA2) and -2.065 microV (CZA1).


CONCLUSIONS
there is no statistically significant difference between the latency and amplitude when we compared males and females, right and left sides in the elderly and between chronologic ages between adults and elderly subjects.
Buranelli
Gabriela
G
University of Franca, Franca/SP.
Barbosa
Marcella Brito
MB
Garcia
Cristiane Fregonesi Dutra
CF
Duarte
Sinésio Grace
SG
Marangoni
Antônio Carlos
AC
Coelho
Lucinda M de F Rodrigues
LM
Reis
Ana Cláudia Mirândola Barbosa
AC
Isaac
Myriam de Lima
Mde L
D000158:Acoustic Impedance Tests; D000161:Acoustic Stimulation / Q000379:methods; D000368:Aged; D000369:Aged, 80 and over; D001301:Audiometry, Pure-Tone; D001307:Auditory Perception / Q000502:physiology*; D003430:Cross-Sectional Studies; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011930:Reaction Time / Q000502:physiology*