title: Surgical morbidity and mortality of pediatric brain tumors: a single center audit.
abstract: OBJECTIVE
  The primary aim of this study is to perform an internal quality control of pediatric brain tumor surgery in the neurosurgical department of the VU University Medical Center Amsterdam (The Netherlands). Secondly, this study aims to contribute to the accumulating data concerning outcome in pediatric neurosurgery, in order to establish institutional practice benchmarks.
  
  
  METHODS
  We report the surgical mortality and morbidity of 121 patients (0-18 years) surgically treated for a brain tumor from January 1999 to August 2007. Patients, in whom only a brain tumor biopsy was performed, were excluded.
  
  
  RESULTS
  Mean age at first surgery was 8.2 years. Of the 121 patients, 14 had a second surgery, and two underwent a third surgery (for a total of 137 operations). Of all 121 primary surgeries, 66% were total resections, 26% subtotal resections, and 8% partial resections. The overall surgical morbidity rate in this study was 69% after first surgery, 50% after second surgery, and one out of two after third surgery.
  
  
  CONCLUSIONS
  These overall morbidity rates are comparable to other published mixed case series. The surgical mortality rate was 0.8%; this is comparable to the lowest rates reported for high-volume neurosurgical centers. We encourage other neurosurgical centers to collect, analyze, and publish their data. These data can then serve as a basis for comparison with other pediatric neurosurgical centers and will eventually lead to an improvement of pediatric neurosurgical practice and patient care.
authors.affiliation: Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: F W
authors.initials: FW
authors.lastname: Neervoort
authors.forename: W J R
authors.initials: WJ
authors.lastname: Van Ouwerkerk
authors.forename: H
authors.initials: H
authors.lastname: Folkersma
authors.forename: G J L
authors.initials: GJ
authors.lastname: Kaspers
authors.forename: W P
authors.initials: WP
authors.lastname: Vandertop
mesh_terms: D000046:Academic Medical Centers / Q000706:statistics & numerical data; D000293:Adolescent; D019985:Benchmarking; D001932:Brain Neoplasms / Q000401:mortality* / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003399:Craniotomy; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009426:Netherlands; D038361:Neuronavigation; D011183:Postoperative Complications / Q000401:mortality*; D011786:Quality Control; D012086:Reoperation; D015996:Survival Rate