Guidelines for the labelling of leucocytes with (111)In-oxine. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine.
We describe here a protocol for labelling autologous white blood cells with (111)In-oxine based on previously published consensus papers and guidelines. This protocol includes quality control and safety procedures and is in accordance with current European Union regulations and International Atomic Energy Agency recommendations.
Roca
Manel
M
Radiopharmacy Unit, Nuclear Medicine Department, Hospital Universitario de Bellvitge, Barcelona, Spain.
de Vries
Erik F J
EF
Jamar
Francois
F
Israel
Ora
O
Signore
Alberto
A
D000328:Adult; D002469:Cell Separation / Q000379:methods; D002634:Chemotaxis, Leukocyte; D002675:Child, Preschool; D006801:Humans; D007205:Indium Radioisotopes / Q000493:pharmacokinetics; D007239:Infections / Q000000981:diagnostic imaging; D007249:Inflammation / Q000000981:diagnostic imaging; D007553:Isotope Labeling / Q000379:methods*; D007962:Leukocytes; D009942:Organometallic Compounds / Q000493:pharmacokinetics; D015125:Oxyquinoline / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D011835:Radiation Protection / Q000331:legislation & jurisprudence / Q000379:methods; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014018:Tissue Distribution
D007205:Indium Radioisotopes; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; C032950:indium oxine; D015125:Oxyquinoline