title: Identification of unusual truncated forms of nucleocapsid protein in MDCK cells infected by Avian influenza virus (H9N2).
abstract: Unusual truncated forms of nucleocapsid protein (NP) were identified in the lysate of MDCK cells infected by Avian influenza virus (H9N2) using MS-based proteomics approach. Moreover, O-sulfonation that was considered as an unusual modification was identified in one of the tryptic peptides from the truncated NP. The findings might have implications on better understanding on the role of nucleoprotein in Avian influenza virus-host interaction.
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, P R China.
authors.forename: Ning
authors.initials: N
authors.lastname: Liu
authors.forename: Wenjun
authors.initials: W
authors.lastname: Song
authors.forename: Pui
authors.initials: P
authors.lastname: Wang
authors.forename: Kim-Chung
authors.initials: KC
authors.lastname: Lee
authors.forename: Zongwei
authors.initials: Z
authors.lastname: Cai
authors.forename: Honglin
authors.initials: H
authors.lastname: Chen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D053127:Influenza A Virus, H9N2 Subtype / Q000737:chemistry* / Q000235:genetics; D008969:Molecular Sequence Data; D019590:Nucleocapsid Proteins / Q000032:analysis* / Q000737:chemistry / Q000235:genetics; D016366:Open Reading Frames; D040901:Proteomics; D014158:Transcription, Genetic
chemical_list: D019590:Nucleocapsid Proteins