Development of a pulsatile flow-generating circulatory-assist device.
We developed a new circulation-assist device that can generate pulsatile assist flow synchronized with the patient's diastolic phase. The device is composed of a drainage tube, a centrifugal pump, an oxygenator, and a sending tube. A portable magnetic valve device composed of a pulse generator and a tamper, which produces intermittent mechanical compression, is attached to the pillow of the sending tube. Preliminary animal experiments were conducted. No changes in the animals' hemodynamics or any device problems were observed during a preliminary 48-h test run. Significant diastolic augmentation was confirmed. This new device may be useful in treating patients with severe heart failure and could be more useful than using percutaneous cardiopulmonary support (PCPS) alone.
Inamori
Syuji
S
Department of Clinical Engineering, Faculty of Health Sciences, Hiroshima International University, Hiroshima, Japan.
Fujii
Yutaka
Y
Oshita
Tomoya
T
Kobayashi
Yutaka
Y
Minamiyama
Motomu
M
Sasaki
Sinobu
S
Murakami
Takashi
T
Sakuma
Ichiro
I
Gunshin
Masataka
M
Suematsu
Yoshihiro
Y
Yahagi
Naoki
N
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D003971:Diastole / Q000502:physiology; D004867:Equipment Design / Q000295:instrumentation; D006333:Heart Failure / Q000601:surgery*; D006353:Heart-Assist Devices; D008297:Male; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology*; D011817:Rabbits