[Studies on the chemical constituents from the seed of Forsythia suspense].
OBJECTIVE
To study the chemical constituents in the seed of Forsythia suspense.


METHODS
The compounds were isolated by column chromatography on silica gel and Sephadex LH-20; Their structures were identified by spectral data and other methods.


RESULTS
Seven compounds were isolated and identified as beta-Amyrin acetate (I); 20(S)-Dammar-24-ene-3beta,20-diol-3-acetate (II); 18-nor-5a, 20s-cholanic acid, 3beta-20-dihydroxy-4,4,8, 14-tetramethyl-y-lactone, acetate (III); 20S,24S-epoxydammarane-25-ol-3alpha-yl acetate (IV); betulinic acid (V); protocatechuic acid (VI); octahydro-1H,5H-dipyrrolo[1,2-a: 1',2'-d] pyrazine (VII).


CONCLUSIONS
Compound I-VII are isolated from the seed of Forsythia suspense for the first time, and compound VII is a new natural compound.
Cai
Qian
Q
Pharmacy College, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China. caiqianmail@sina.com
Liu
Yu-qiang
YQ
Feng
Xue
X
D031657:Forsythia / Q000737:chemistry*; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D053978:Pentacyclic Triterpenes; D010946:Plants, Medicinal / Q000737:chemistry; D012639:Seeds / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000094062:Betulinic Acid
D062385:Hydroxybenzoates; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; C009091:protocatechuic acid; D009828:Oleanolic Acid; C000265:beta-amyrin acetate; D000094062:Betulinic Acid