title: Neuropathic pain in children: Special considerations.
abstract: Neuropathic pain is relatively uncommon in children. Although some syndromes closely resemble those found in adults, the incidence and course of the condition can vary substantially in children, depending on developmental status and contextual factors. There are some neuropathic pain syndromes that are rare and relatively unique to the pediatric population. This article discusses the array of neuropathic pain conditions in children and available treatment strategies. Data are limited by small numbers and few randomized controlled trials. Research and clinical implications are discussed.
authors.affiliation: Department of Anesthesiology & Pain Medicine, Seattle Children's Hospital, WA 98105, USA. gawalco@u.washington.edu
authors.forename: Gary A
authors.initials: GA
authors.lastname: Walco
authors.forename: Robert H
authors.initials: RH
authors.lastname: Dworkin
authors.forename: Elliot J
authors.initials: EJ
authors.lastname: Krane
authors.forename: Alyssa A
authors.initials: AA
authors.lastname: LeBel
authors.forename: Rolf-Detlef
authors.initials: RD
authors.lastname: Treede
mesh_terms: D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002662:Child Health Services / Q000458:organization & administration; D002669:Child Welfare; D020918:Complex Regional Pain Syndromes / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications; D004305:Dose-Response Relationship, Drug; D019317:Evidence-Based Medicine; D006801:Humans; D009437:Neuralgia / Q000145:classification / Q000188:drug therapy* / Q000209:etiology*; D051474:Neuralgia, Postherpetic / Q000150:complications; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D010523:Peripheral Nervous System Diseases / Q000150:complications; D016032:Randomized Controlled Trials as Topic
chemical_list: D000700:Analgesics; D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal