title: Bone particles and the undersized surgical technique.
abstract: During the installation of implants, osteogenic bone particles are translocated along the surface. These particles may contribute to peri-implant bone healing. Based on this phenomenon, it is hypothesized that implants placed with undersized drilling, besides showing higher primary-implant stability, also enhance the amount and osteogenic responses of these bone particles. Biocomp implants were inserted into bicortical fresh-cadaver bone by a press-fit or an undersized surgical technique, and peak-insertion torque values (ITV) were measured. After explantation, the implants were incubated in culture medium up to 24 days. Histology, bone-implant contact (BIC), micro-CT, scanning electron microscopy (SEM), and calcium (Ca) measurements were performed. ITV were significantly higher for implants placed with an undersized technique. Moreover, histology, BIC, micro-CT, SEM, and Ca measurements confirmed the presence of more bone-like tissue on implants inserted with an undersized technique. The undersized surgical technique not only results in higher primary-implant stability, but also induces more translocated bone particles, thus having a positive influence on the osteogenic response.
authors.affiliation: Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, the Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Tabassum
authors.forename: X F
authors.initials: XF
authors.lastname: Walboomers
authors.forename: J G C
authors.initials: JG
authors.lastname: Wolke
authors.forename: G J
authors.initials: GJ
authors.lastname: Meijer
authors.forename: J A
authors.initials: JA
authors.lastname: Jansen
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000502:physiology / Q000648:ultrastructure*; D002113:Calcification, Physiologic / Q000502:physiology; D002118:Calcium / Q000032:analysis; D003758:Dental Implantation, Endosseous / Q000295:instrumentation / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D006041:Goats; D021621:Imaging, Three-Dimensional; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology; D013499:Surface Properties; D013997:Time Factors; D046509:Tissue Culture Techniques; D019415:Torque; D055114:X-Ray Microtomography
chemical_list: D015921:Dental Implants; D002118:Calcium