title: Palladium-catalyzed benzylic addition of 2-methyl azaarenes to N-sulfonyl aldimines via C-H bond activation.
abstract: An efficient protocol for the generation of amines by palladium-catalyzed nucleophilic benzylic addition of 2-methyl-substituted azaarenes to N-sulfonyl aldimines under neutral conditions via C-H bond activation has been developed. This reaction represents a very efficient methodology for the synthesis of heterocycle-containing amines and thus opens a new way to access amines through C-H bond activation.
authors.affiliation: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, Lanzhou 730000, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Qian
authors.forename: Shengmei
authors.initials: S
authors.lastname: Guo
authors.forename: Jianping
authors.initials: J
authors.lastname: Shao
authors.forename: Qiming
authors.initials: Q
authors.lastname: Zhu
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Chungu
authors.initials: C
authors.lastname: Xia
authors.forename: Hanmin
authors.initials: H
authors.lastname: Huang