title: A dual role for hippocampal replay.
abstract: Hippocampal place cells are active when the rat is at certain locations. The sequence of these active place cells is known to be rapidly replayed during sharp-wave-ripple events in the EEG. In this issue of Neuron, a study by Gupta et al. challenges previous notions that the replayed trajectories are solely a passive echo of past episodes. Rather, replay might also be an active process constructing a Tolmanian cognitive map of space, which makes flexible navigation possible.
authors.affiliation: Kavli Institute for Systems Neuroscience and the Centre for the Biology of Memory, Norwegian University of Science and Technology, N-7489, Trondheim, Norway. dori.derdikman@ntnu.no
authors.forename: Dori
authors.initials: D
authors.lastname: Derdikman
authors.forename: May-Britt
authors.initials: MB
authors.lastname: Moser
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000166:cytology* / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D051381:Rats; D013037:Spatial Behavior / Q000502:physiology*