title: [Spontaneous regression of hepatocellular carcinomas].
abstract: We report a rare case of spontaneous regression (SR) of hepatocellular carcinoma (HCC). A 70-year-old man consulted us for general fatigue. Enhanced abdominal computed tomography (CT) showed two HCCs, of 5cm in the posterior segment and 8cm around the right Glissonean pedicle with tumor thrombus in the main portal trunk. He refused to undergo any treatment, but 28 months later, CT showed complete disappearance of the hilar tumor and portal tumor thrombus, and partial regression in the posterior tumor with shrinkage of the right lobe of the liver. His PIVKA-II levels decreased from 23358 to 217mAU/ml. In the present case, tumor infarction of the portal thrombus, and the administration of imidapuril hydrochloride and Hochu-ekki-to may have caused SR.
authors.affiliation: Second Department of Surgery, Hamamatsu University School of Medicine, Japan. tharada@hama-med.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Harada
authors.forename: Takanori
authors.initials: T
authors.lastname: Sakaguchi
authors.forename: Keisuke
authors.initials: K
authors.lastname: Inaba
authors.forename: Toshio
authors.initials: T
authors.lastname: Nakamura
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Kurachi
authors.forename: Atsuko
authors.initials: A
authors.lastname: Fukazawa
authors.forename: Koichi
authors.initials: K
authors.lastname: Nakamura
authors.forename: Tomoki
authors.initials: T
authors.lastname: Sawayanagi
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Hara
authors.forename: Katsuya
authors.initials: K
authors.lastname: Ida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konno
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology*