[A severe case of infectious mononucleosis associated with ciprofloxacin and salazopyrin administration].
We report a case of rash probably induced by ciprofloxacin and/or salazopyrin administration in a patient with infectious mononucleosis. A 22 year woman developed a maculopapular and petechial eruption in the 3-rd day of ciprofloxacin (given for a genital tract infection) and the 32-nd day of salazopyrin (for a spondylodiscitis). Subsequently she developed a severe hepatitis, shock, and very severe leucocytosis (88 000/mmc) that occasioned haematological investigations for a lymphoproliferative syndrome.
Miftode
Egidia
E
Facultatea de Medicină, Disciplina de Boli Infecţioase, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Leca
Daniela
D
Luca
V
V
D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D015299:Discitis / Q000188:drug therapy; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology; D004359:Drug Therapy, Combination; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000175:diagnosis*; D011537:Pruritus / Q000139:chemically induced; D012720:Severity of Illness Index; D012769:Shock / Q000139:chemically induced; D012460:Sulfasalazine / Q000008:administration & dosage / Q000009:adverse effects*
D000890:Anti-Infective Agents; D018501:Antirheumatic Agents; D012460:Sulfasalazine; D002939:Ciprofloxacin