[Effects of indol-3-carbinol and epigallocatexin-3-gallate on alteration and reparation in affected urethra of experimental animals].
The effects of indol-3-carbinol and epigallocatexin-3-gallate on alteration and reparation in the urethra were studied in 30 male Shinshilla rabbits. From the observation day 2 the rabbits were fed with indol-3-carbinol and epigallocatexin-3-gallate in addition to standard diet. Microcirculation was assessed with a laser analyzer of capillary circulation LAKK-01 which detected earlier recovery of microcirculation in the group of the animals fed with indol-3-carbinol and epigallocatexin-3-gallate. Thus, antioxidant and antiproliferative properties of indol-3-carbinol and epigallocatexin-3-gallate improve alteration and reparation in affected urethra due to development of soft elastic connective tissue with better capillary circulation.
Pavlov
V N
VN
Kazikhinurov
A A
AA
Safiullin
R I
RI
Kazikhinurov
R A
RA
Kutushev
K G
KG
Valiev
I R
IR
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D002392:Catechin / Q000031:analogs & derivatives* / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology*; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D011817:Rabbits; D012038:Regeneration / Q000187:drug effects*; D014521:Urethra / Q000098:blood supply / Q000293:injuries* / Q000473:pathology
D016588:Anticarcinogenic Agents; D000975:Antioxidants; D007211:Indoles; D002392:Catechin; C045651:epigallocatechin gallate; C016517:indole-3-carbinol