Omega-3 fatty acids and blood pressure.
There is substantial evidence that omega-3 fatty acids reduce blood pressure, with a greater effect in hypertensive patients and those with high-normal blood pressure. The dose of omega-3 fatty acids required to achieve a blood pressure reduction is likely to be at least 3-4 g/day. However, the magnitude of the blood pressure change can be increased by salt restriction or when omega-3 fatty acids are incorporated into a weight reducing program. It is also highly plausible that increased omega-3 fatty acid consumption as part of a dietary change including increased consumption of fruits and vegetables, and moderation of salt intake, will confer significant cardiovascular benefit.
Mori
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TA
School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Cardiovascular Research Centre, Perth, Western Australia, Australia. trevor.mori@uwa.edu.au
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002395:Catecholamines / Q000502:physiology; D018849:Controlled Clinical Trials as Topic; D004727:Endothelium / Q000187:drug effects; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology*; D005260:Female; D006801:Humans; D015201:Meta-Analysis as Topic; D011159:Population Surveillance; D051381:Rats; D014664:Vasodilation / Q000187:drug effects
D000959:Antihypertensive Agents; D002395:Catecholamines; D015525:Fatty Acids, Omega-3