title: Relationship of parental bonding styles with gray matter volume of dorsolateral prefrontal cortex in young adults.
abstract: Previous epidemiologic studies using the parental bonding instrument (PBI), a self-report scale to rate attitudes of parents during the first 16 years, have suggested that a lower parental care score or higher parental overprotection score could lead to an increased risk of several psychiatric disorders, including schizophrenia and mood disorder. However, neuroimaging studies of an association between PBI scores and brain developmental abnormalities are still limited. In this region-of-interest analysis study using a cross-sectional design, we examined 50 normal young adults, in terms of relationships of parental bonding styles during the first 16 years measured by PBI with regional gray matter (GM) volume in the dorsolateral prefrontal cortex (DLPFC). Our study showed that paternal care score positively correlated with the GM volume in the left DLPFC, and paternal and maternal overprotection score negatively correlated with the GM volume in the left DLPFC. In conclusion, our results suggest that in normal young adults, lower paternal care and higher parental overprotection scores correlated with the GM volume reduction in the DLPFC.
authors.affiliation: Department of Psychiatry and Human Behavior, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan. knarita@med.gunma-u.ac.jp
authors.forename: Kosuke
authors.initials: K
authors.lastname: Narita
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takei
authors.forename: Masashi
authors.initials: M
authors.lastname: Suda
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Aoyama
authors.forename: Toru
authors.initials: T
authors.lastname: Uehara
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kosaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Amanuma
authors.forename: Masato
authors.initials: M
authors.lastname: Fukuda
authors.forename: Masahiko
authors.initials: M
authors.lastname: Mikuni
mesh_terms: D000328:Adult; D001921:Brain / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D036421:Nerve Fibers, Unmyelinated; D009769:Object Attachment; D010287:Parent-Child Relations; D017397:Prefrontal Cortex / Q000033:anatomy & histology*