Evaluation of seven X-chromosomal short tandem repeat loci located within the Xq26 region.
In this study a set of 29 X-chromosomal short tandem repeats (STRs) located within the Xq26 region was evaluated. These STRs were found within the 133.14-133.45Mb region around the HPRTB locus. Evaluation of the microsatellites was performed with regard to polymorphism, reliable amplification, and low stutter artefacts. DXS10101, DXS10102, and DXS10103 were identified as those X-STRs with highest diversity; i.e. PIC values of 0.7174-0.8933. The locus DXS10101 was the optimal candidate for the integration in the commercial available test system Mentype Argus X-8 PCR amplification kit.
Rodig
Heike
H
Biotype AG, Moritzburger Weg 67, 01109 Dresden, Germany.
Kloep
Frank
F
Weissbach
Lydia
L
Augustin
Christa
C
Edelmann
Jeannett
J
Hering
Sandra
S
Szibor
Reinhard
R
Götz
Frank
F
Brabetz
Werner
W
D041321:Chromosomes, Human, X; D017931:DNA Primers; D004586:Electrophoresis; D006239:Haplotypes; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA; D020080:Tandem Repeat Sequences
D017931:DNA Primers