title: The contribution of the Epstein-Barr virus to the pathogenesis of childhood lymphomas.
abstract: The Epstein-Barr virus (EBV) is a lymphotropic herpes virus with oncogenetic properties which can lead to the development of lymphomas such as Burkitt's lymphoma (BL), Hodgkin's lymphoma (HL), or post-transplant lymphoma. This review discusses our current understanding of lymphomagenesis in relation to EBV and the potential for targeted therapies.
authors.affiliation: Cancer Research UK Institute for Cancer Studies, University of Birmingham, UK.
authors.forename: Fathima Zumla
authors.initials: FZ
authors.lastname: Cader
authors.forename: Pamela
authors.initials: P
authors.lastname: Kearns
authors.forename: Lawrence
authors.initials: L
authors.lastname: Young
authors.forename: Paul
authors.initials: P
authors.lastname: Murray
authors.forename: Martina
authors.initials: M
authors.lastname: Vockerodt
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002051:Burkitt Lymphoma / Q000209:etiology / Q000821:virology; D002648:Child; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000209:etiology / Q000821:virology; D006801:Humans; D016219:Immunotherapy, Adoptive; D008223:Lymphoma / Q000209:etiology* / Q000821:virology; D016393:Lymphoma, B-Cell / Q000209:etiology / Q000821:virology; D008232:Lymphoproliferative Disorders / Q000209:etiology / Q000821:virology
chemical_list: D000998:Antiviral Agents