title: The role of antibodies in inflammatory arthritis.
abstract: Inflammatory arthritis presents in a variety of diseases, from rheumatoid arthritis to hepatitis. Antibodies to autoantigens or to microbial constituents are commonly associated with these conditions. In some cases, the antibodies have diagnostic and prognostic relevance. It cannot as yet be determined definitively that any of them mediate joint damage, although the evidence from animal models indicates that this mechanism is likely. The purpose of this article is to give an overview of the spectrum of antibodies found in a variety of inflammatory arthritides. The relevant animal models are also discussed.
authors.affiliation: Department of Medicine, Pennsylvania Hospital, Philadelphia, PA, USA.
authors.forename: Ann
authors.initials: A
authors.lastname: Duskin
authors.forename: Robert A
authors.initials: RA
authors.lastname: Eisenberg
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D001324:Autoantigens / Q000276:immunology*; D015551:Autoimmunity; D000939:Epitopes; D006801:Humans; D018836:Inflammation Mediators / Q000276:immunology
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D000939:Epitopes; D018836:Inflammation Mediators