Cerebral and peripheral tissue oxygenation in children supported on ECMO for cardio-respiratory failure.
Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure. Establishing, maintaining and weaning from ECMO may increase the risk for intracranial injury. We used a dual channel near infrared system to monitor cerebral and peripheral tissue oxygenation in 3 venoarterial (VA) and 1 venovenous (VV) ECMO patients undergoing manipulations in the ECMO circuit flows. Spectral analysis was performed on the oxyhaemoglobin data collected from these patients with the aim of comparing oscillations at range of frequencies appearing in the two measurement sites.
Papademetriou
Maria D
MD
Biomedical Optics Research Laboratory, Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK. mpapa@medphys.ucl.ac.uk
Tachtsidis
Ilias
I
Leung
Terence S
TS
Elliott
Martin J
MJ
Hoskote
Aparna
A
Elwell
Clare E
CE
D001921:Brain / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D006333:Heart Failure / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007866:Leg / Q000503:physiopathology*; D010100:Oxygen / Q000378:metabolism*; D010108:Oxyhemoglobins / Q000378:metabolism; D012131:Respiratory Insufficiency / Q000150:complications* / Q000503:physiopathology
D010108:Oxyhemoglobins; D010100:Oxygen