Molecular diversity of spider venom.
Spider venom, a factor that has played a decisive role in the evolution of one of the most successful groups of living organisms, is reviewed. Unique molecular diversity of venom components including substances of variable structure (from simple low molecular weight compounds to large multidomain proteins) with different functions is considered. Special attention is given to the structure, properties, and biosynthesis of toxins of polypeptide nature.
Vassilevski
A A
AA
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kozlov
S A
SA
Grishin
E V
EV
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D004220:Disulfides / Q000737:chemistry; D006801:Humans; D019476:Insect Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D008970:Molecular Weight; D010455:Peptides / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D013111:Spider Venoms / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D013112:Spiders
D004220:Disulfides; D019476:Insect Proteins; D010455:Peptides; D013111:Spider Venoms