Ileocolonic mucormycosis in adult immunocompromised patients: a surgeon's perspective.
We report three cases of ileocolic mucormycosis in adult immunocompromised patients presenting as acute abdomen. All patients underwent laparotomy but two of them died from multiorgan failure before the diagnoses were confirmed. The diagnosis of gastrointestinal mucormycosis is rarely suspected, and antemortem diagnosis is made in only 25%-50% of cases. These cases illustrate the difficulty encountered by surgeons in managing acute abdomen in neutropenic patients with hematological malignancy. The management of colonic mucormycosis in the published literature is also reviewed.
Lo
Oswens Siu-Hung
OS
Division of Colorectal Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam Road, Hong Kong, China.
Law
Wai-Lun
WL
D000006:Abdomen, Acute / Q000276:immunology / Q000382:microbiology; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003108:Colonic Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007077:Ileal Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D016867:Immunocompromised Host; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D009102:Multiple Organ Failure / Q000276:immunology / Q000382:microbiology; D009503:Neutropenia / Q000276:immunology; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D016896:Treatment Outcome; D055815:Young Adult
D000935:Antifungal Agents; D000970:Antineoplastic Agents