Computed tomography findings in radiation-induced osteosarcoma of the jaws.
OBJECTIVE
The objective of this study was to report the CT appearances of radiation-induced jaw osteosarcomas (RIJOS) following therapeutic irradiation.


METHODS
The CT studies of 7 subjects with RIJOS were reviewed retrospectively.


RESULTS
RIJOS developed at 3 to 14 years following radiotherapy. Four patients had tumors in the maxilla and 3 in the mandible. Five tumors were osteoblastic, with 1 osteolytic and 1 mixed lesions. Osteoid tumor matrix mineralization was identified in 6 subjects. Periosteal reaction was demonstrated in 6 cases. All subjects showed a soft tissue extension component beyond the area of bone destruction.


CONCLUSIONS
CT is a useful tool to identify RIJOS and plays an important role in preoperative assessment of the extent of the tumor.
Shao
Ziyang
Z
Department of Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China.
He
Yu
Y
Wang
Lizhen
L
Hu
Haisheng
H
Shi
Huimin
H
D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging* / Q000473:pathology; D012516:Osteosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed