[Inappropriate antidiuretic hormone secretion induced by sodium valproate].
The occurrence of a syndrome of inappropriate antidiuretic hormone secretion (SIADH) with sodium valproate has been rarely described in the literature. We present a 46-year-old patient, admitted to the Emergency Room for confusion and acute agitation. The exploration showed a severe hyponatraemia induced by sodium valproate, prescribed for a type I bipolar disorder. This article addresses both somatic and psychiatric issues in the differential diagnosis of confusion and agitation.
Bève
E
E
Service de Psychiatrie et Psychologie médicale, CHU de Liège, Belgique.
Beck
E
E
Pinto
E
E
Ansseau
M
M
D018692:Antimanic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects*
D018692:Antimanic Agents; D014635:Valproic Acid