Identification of unusual truncated forms of nucleocapsid protein in MDCK cells infected by Avian influenza virus (H9N2).
Unusual truncated forms of nucleocapsid protein (NP) were identified in the lysate of MDCK cells infected by Avian influenza virus (H9N2) using MS-based proteomics approach. Moreover, O-sulfonation that was considered as an unusual modification was identified in one of the tryptic peptides from the truncated NP. The findings might have implications on better understanding on the role of nucleoprotein in Avian influenza virus-host interaction.
Liu
Ning
N
Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, P R China.
Song
Wenjun
W
Wang
Pui
P
Lee
Kim-Chung
KC
Cai
Zongwei
Z
Chen
Honglin
H
D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D053127:Influenza A Virus, H9N2 Subtype / Q000737:chemistry* / Q000235:genetics; D008969:Molecular Sequence Data; D019590:Nucleocapsid Proteins / Q000032:analysis* / Q000737:chemistry / Q000235:genetics; D016366:Open Reading Frames; D040901:Proteomics; D014158:Transcription, Genetic
D019590:Nucleocapsid Proteins