title: Functionally uni-leaflet mitral valves in a family: a case series.
abstract: Functionally uni-leaflet mitral valves are extremely rare. In severe cases, they are considered incompatible with life beyond the neonatal period. We present a case series of three adults with almost complete absence of the posterior mitral valve leaflet and who are asymptomatic, with no more than mild mitral regurgitation. We believe that this is the first reported instance of such findings in a single family.
authors.affiliation: Department of Medical Physics, Grantham & District Hospital, Grantham, Lincolnshire, UK.
authors.forename: Prathap
authors.initials: P
authors.lastname: Kanagala
authors.forename: Stephanie
authors.initials: S
authors.lastname: Baker
authors.forename: Lawrence
authors.initials: L
authors.lastname: Green
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Houghton
mesh_terms: D000293:Adolescent; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D009035:Mothers; D010375:Pedigree; D011379:Prognosis; D018570:Risk Assessment; D035781:Siblings; D014463:Ultrasonography