title: Disseminated intravascular coagulation associated with ventriculoperitoneal shunt surgery.
abstract: Disseminated intravascular coagulation (DIC) as a complication of surgery for ventriculoperitoneal (VP) shunts is extremely rare, and only one case has been documented in the literature. The authors present the case of a 9-year-old girl with shunted hydrocephalus who presented with a 3-day history of headaches and vomiting. A head CT showed enlarged ventricles compared with baseline. An emergent VP shunt revision was performed, during which an obstructed proximal catheter was found. Immediately after extubation, the patient became apneic and progressed to cardiopulmonary arrest. A breathing tube was reinserted followed by resuscitation attempts that led to extracorporeal membrane oxygenation. Soon after reintubation, bloody drainage was noted in the endotracheal tube, and subsequent laboratory studies were consistent with DIC. The patient died on postoperative Day 1, and autopsy findings confirmed DIC. Note that DIC is a recognized complication of trauma, particularly with brain injury, but it is rare with neurosurgical procedures. Disseminated intravascular coagulation should be considered if excessive bleeding occurs after any brain insult.
authors.affiliation: Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
authors.forename: James L
authors.initials: JL
authors.lastname: Frazier
authors.forename: G Steven
authors.initials: GS
authors.lastname: Bova
authors.forename: Kathryn
authors.initials: K
authors.lastname: Jockovic
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Hunt
authors.forename: Benjamin
authors.initials: B
authors.lastname: Lee
authors.forename: Edward S
authors.initials: ES
authors.lastname: Ahn
mesh_terms: D002648:Child; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000473:pathology / Q000628:therapy*; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*