title: GABAergic and glycinergic control of upper airway motoneurons in rapid eye movement sleep.
abstract: The aim of this study was to determine if GABA(B) receptors play a role in suppressing upper airway muscle tone in rapid eye movement (REM) sleep. The results reported herein indicate that GABA(B) receptors, acting in concert with GABA(A) and glycine receptors, play a role in mediating REM sleep atonia.
authors.affiliation: Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada. patti.brooks@utoronto.ca
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Brooks
authors.forename: John H
authors.initials: JH
authors.lastname: Peever
mesh_terms: D000818:Animals; D001596:Benzylamines / Q000494:pharmacology; D004569:Electroencephalography; D004576:Electromyography; D005998:Glycine / Q000378:metabolism*; D008297:Male; D008406:Masseter Muscle / Q000187:drug effects / Q000378:metabolism / Q000502:physiology; D009046:Motor Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D010721:Phosphinic Acids / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D018080:Receptors, GABA-B / Q000378:metabolism; D012137:Respiratory System / Q000166:cytology* / Q000378:metabolism; D012895:Sleep, REM / Q000187:drug effects / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D001596:Benzylamines; D010721:Phosphinic Acids; D018080:Receptors, GABA-B; C083008:CGP 52432; D005680:gamma-Aminobutyric Acid; D005998:Glycine