Micronodular T-cell/histiocyte-rich B-cell lymphoma of the spleen in a case of small lymphocytic lymphoma: a Richter's transformation.
Abstract A case of micronodular T-cell/histiocyte-rich B-cell lymphoma of the spleen who had a prior diagnosis of small lymphocytic lymphoma is presented. Micronodular T-cell/histiocyte-rich B-cell lymphoma of the spleen was first described in 2003, and very few cases have been reported since then. This is the first reported case supervening in a patient with pre-existing chronic lymphocytic lymphoma. We review its clinical, pathologic, and immunohistochemical features and the difficulties we encountered during diagnosis.
Türköz
Hüseyin Kemal
HK
Department of Pathology, Marmara University School of Medicine, and Sisli Etfal Education and Research Hospital, Istanbul, Turkey. kemal.turkoz@marmara.edu.tr
Polat
Nedim
N
Akin
Ilker
I
Ozcan
Deniz
D
D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000473:pathology