Ultrasound promoted selective synthesis of 2-aryl-5,6-dihydro-4H-1,3-oxazines catalyzed by K-10 and KSF montmorillonite clays: a practical procedure under mild and solvent-free conditions.
Montmorillonite K-10 and KSF were found to be highly efficient, environmentally friendly and recyclable heterogeneous catalysts for the selective synthesis of a variety of 2-aryl-5,6-dihydro-4H-1,3-oxazines from arylnitriles and 3-amino-1-propanol under ultrasound irradiation. This new methodology provides excellent yields in short reaction times (10-25 min). The reaction work-up is very simple and the catalysts can be easily separated from the reaction mixture and reused several times in subsequent reactions. This catalytic system also exhibits excellent chemoselectivity in the synthesis of mono-oxazines from dinitriles.
Mohammadpoor-Baltork
Iraj
I
Department of Chemistry, Catalysis Division, University of Isfahan, Isfahan 81746-73441, Iran. imbaltork@sci.ui.ac.ir
Moghadam
Majid
M
Tangestaninejad
Shahram
S
Mirkhani
Valiollah
V
Eskandari
Zohre
Z
D000538:Aluminum Silicates / Q000737:chemistry* / Q000528:radiation effects; D001546:Bentonite / Q000737:chemistry* / Q000528:radiation effects; D000077215:Clay; D010078:Oxazines / Q000138:chemical synthesis* / Q000528:radiation effects*; D012997:Solvents / Q000737:chemistry* / Q000528:radiation effects; D013010:Sonication
D000538:Aluminum Silicates; D010078:Oxazines; D012997:Solvents; C503188:montmorillonite K-10; C523398:montmorillonite KSF; D001546:Bentonite; D000077215:Clay