title: Total regioselective transformation of aromatic aziridine 2-carboxamides into 2-aminoamides promoted by active manganese.
abstract: A novel, totally regioselective transformation of aromatic N-4-methoxyphenylaziridine 2-carboxamides into 2-aminoamides promoted by active manganese (Mn*) is reported. alpha-Amino ketones can be readily obtained by reaction of morpholine-derived 2-aminoamides with organolithium compounds.
authors.affiliation: Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Spain. jmcg@uniovi.es
authors.forename: José M
authors.initials: JM
authors.lastname: Concellón
authors.forename: Humberto
authors.initials: H
authors.lastname: Rodríguez-Solla
authors.forename: Vicente
authors.initials: V
authors.lastname: Del Amo
authors.forename: Pamela
authors.initials: P
authors.lastname: Díaz
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D018020:Lithium Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009025:Morpholines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D007659:Ketones; D018020:Lithium Compounds; D009025:Morpholines; C518574:aziridine-2-carboxamide; D008345:Manganese; C037574:morpholine