title: Catalytic enantioselective 1,3-dipolar cycloaddition of C,N-cyclic azomethine imines with alpha,beta-unsaturated aldehydes.
abstract: A yet-unexploited class of azomethine imines, C,N-cyclic azomethine imines, could be successfully employed in highly enantioselective 1,3-dipolar cycloaddition with enals catalyzed by titanium-BINOLate to give pharmaceutically attractive tetrahydroisoquinoline and piperidine motifs.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Yuko
authors.initials: Y
authors.lastname: Maeda
authors.forename: Masato
authors.initials: M
authors.lastname: Omote
authors.forename: Hiroki
authors.initials: H
authors.lastname: Nakatsu
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka