Oncogenic osteomalacia associated with phosphaturic mesenchymal tumour, mixed connective tissue type of the knee.
One of the most unusual and uncommon types of osteomalacia is the oncogenic osteomalacia that is predominantly caused by a soft tissue or bone tumour, mostly by a phosphaturic mesenchymal tumour, mixed connective tissue type (PMTMCT). We report a case of a 27-year-old male presented with complaints of progressive and generalized muscle weakness, bone pains and multiple fractures. Intra-articular PMTMCT of the knee was diagnosed and surgically removed. We describe histopathological features of PMTMCT and review the most recent studies concerning this diagnostic problem.
Szumera-Ciećkiewicz
Anna
A
Department of Pathology, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, ul. Roentgena 5, 02-781 Warszawa. annacieckiewicz@coi.waw.pl
Ptaszyński
Konrad
K
Pawełas
Andrzej
A
Rutkowski
Piotr
P
D000328:Adult; D001859:Bone Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007719:Knee Joint; D008297:Male; D008637:Mesenchymoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D010018:Osteomalacia / Q000175:diagnosis* / Q000209:etiology