Brain evolution: microcephaly genes weigh in.
The role of microcephaly genes in normal variation in human brain size has been controversial. New studies show that a link does exist and imply sex-specificity in microcephaly gene action during neurogenesis.
Montgomery
Stephen H
SH
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
Mundy
Nicholas I
NI
D000818:Animals; D005075:Biological Evolution; D001921:Brain / Q000254:growth & development*; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; D005260:Female; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D006801:Humans; D008831:Microcephaly / Q000235:genetics*; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D020641:Polymorphism, Single Nucleotide
C467202:ASPM protein, human; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; C460645:MCPH1 protein, human; D009419:Nerve Tissue Proteins