title: [New conception of surgery in Peyronie's disease].
abstract: Clinical experience of the authors on patients with Peyronie's disease shows that intraplaque therapy with verapamil and interferon and a malignant course of the disease can result in shortening of the penis (4 and 1 cases were observed, respectively). The length of the penis diminished by 30 to 50%. The patients were treated with graft corporoplasty with endoprosthesis of the penis. Basing on the experience with these cases the following conclusions were made: intraplaque injections are hard to perform and can provoke progression of the disease; long-term conservative treatment for stabilization of the active stage of Peyronie's disease can lead to shortening of the penis; in malignant course of the disease and progressive shortening of the penis surgical policy is justified despite "acute" phase of the disease.
authors.forename: V A
authors.initials: VA
authors.lastname: Kovalev
authors.forename: S G
authors.initials: SG
authors.lastname: Karaguzhin
authors.forename: S V
authors.initials: SV
authors.lastname: Koroleva
authors.forename: A N
authors.initials: AN
authors.lastname: Abdulkhamidov
authors.forename: M G
authors.initials: MG
authors.lastname: Levadnaia
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D006801:Humans; D007372:Interferons / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010411:Penile Induration / Q000473:pathology* / Q000601:surgery*; D013521:Urologic Surgical Procedures, Male / Q000379:methods*; D014665:Vasodilator Agents / Q000008:administration & dosage; D014700:Verapamil / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D014665:Vasodilator Agents; D007372:Interferons; D014700:Verapamil