Transfer of two-dimensional patterns of human umbilical vein endothelial cells into fibrin gels to facilitate vessel formation.
Two-dimensional cell patterns prepared on substrate surfaces by an electrochemical-based biolithography method have been transferred into fibrin gels prepared in situ. Line patterns of human umbilical vein endothelial cells (HUVECs) in the gel that was strained after the transfer formed a linear vessel-like structure within 8 days.
Kawashima
Takeaki
T
Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01, Aramaki, Aoba-ku, Sendai 980-8579, Japan.
Yokoi
Takeshi
T
Kaji
Hirokazu
H
Nishizawa
Matsuhiko
M
D002478:Cells, Cultured; D004563:Electrochemistry; D004730:Endothelium, Vascular / Q000166:cytology*; D005337:Fibrin; D006801:Humans; D020100:Hydrogels; D014471:Umbilical Veins / Q000166:cytology*
D020100:Hydrogels; D005337:Fibrin