title: Improvement in dynamic range limitation of swept source optical coherence tomography by true logarithmic amplification.
abstract: We previously demonstrated, with both theoretical and experimental studies, the dynamic range limitation with spectral domain optical coherence tomography (OCT) relative to time domain OCT. A significant portion of this limitation was due to the difference of analog/digital conversion. In this paper, a new method of true logarithmic amplification is discussed theoretically and tested experimentally to increase the dynamic range of a swept source OCT. With the current experimental setup, an increase of the dynamic range by about 6 dB was obtained.
authors.affiliation: Center for Optical Coherence Tomography and Optical Physics, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Ehsan
authors.initials: E
authors.lastname: Azimi
authors.forename: Mark E
authors.initials: ME
authors.lastname: Brezinski
mesh_terms: D000465:Algorithms; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*