title: [Evaluation of biological activity of a dermatological preparation with elaeagnus angustifolia flowers soft extract].
abstract: It was elaborated a dermatological preparation with 6% g Elaeagnus angustifolia flowers soft extract incorporated in water washable cream base.
  
  
  METHODS
  The soft extract contents resins with a wound healing activity, flavones and polyphenols with antioxidant activity. This extract was standardized in flavones (0.965-1.465%) and polyphenols (1.076-1.348%).
  
  
  RESULTS
  The dermatological preparation has a low antioxidant activity (AA% = 25.7%), half of soft extract antioxidant activity (AA% = 45.9%), tested by chemiluminescence method. The wound healing effect of the dermatological preparation was tested on rabbit scarred skin.
  
  
  CONCLUSIONS
  The dermatological preparation had a superior activity than a control untreated or treated with washable cream base.
authors.affiliation: Disciplina Farmacognozie, Universitatea Ovidius Constantă, Facultatea de Medicină Dentară si Farmacie.
authors.forename: Laura
authors.initials: L
authors.lastname: Bucur
authors.forename: Gh
authors.initials: G
authors.lastname: Tarălungă
authors.forename: Rodica
authors.initials: R
authors.lastname: Alexandrescu
authors.forename: Ticuţa
authors.initials: T
authors.lastname: Negreanu
authors.forename: Viorica
authors.initials: V
authors.lastname: Istudor
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D003879:Dermatologic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004195:Disease Models, Animal; D031263:Elaeagnaceae; D035264:Flowers; D009824:Ointments / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D011817:Rabbits; D016896:Treatment Outcome; D014945:Wound Healing; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; D010936:Plant Extracts