title: Successful treatment of periodontal mucormycosis: report of a case and literature review.
abstract: Mucormycosis is an aggressive and potentially devastating fungal infection which typically manifests in pulmonary, rhinocerebral, or disseminated forms in patients with hematologic malignancy. Mucormycosis confined to the periodontium is uncommon, and to our knowledge only 6 cases have been reported in the English-language literature. This case report describes a patient with acute leukemia and periodontal mucormycosis. Calcofluor fluorescence microscopy is also proposed as a method for establishing a prompt diagnosis and guiding extent of intraoperative surgical debridement.
authors.affiliation: National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA. mcdermottn@nidcr.nih.gov
authors.forename: Nancy E
authors.initials: NE
authors.lastname: McDermott
authors.forename: John
authors.initials: J
authors.lastname: Barrett
authors.forename: Jason
authors.initials: J
authors.lastname: Hipp
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Merino
authors.forename: Chyi-Chia
authors.initials: CC
authors.lastname: Richard Lee
authors.forename: Paige
authors.initials: P
authors.lastname: Waterman
authors.forename: Demetrio L
authors.initials: DL
authors.lastname: Domingo
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Walsh
mesh_terms: D000208:Acute Disease; D003646:Debridement / Q000379:methods; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications* / Q000628:therapy; D010510:Periodontal Diseases / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D010519:Periodontium / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D019172:Transplantation Conditioning / Q000009:adverse effects; D016896:Treatment Outcome