title: Safety of robotic-assisted treadmill therapy in children and adolescents with gait impairment: a bi-centre survey.
abstract: OBJECTIVE
  The aim of the present study was to report on adverse events encountered with robotic-assisted treadmill therapy in children and adolescents with gait disorders.
  
  
  METHODS
  Eighty-nine patients who underwent a trial of robotic assisted treadmill therapy in the two participating centres were analysed. Demographic data and safety data of the patients were analysed using descriptive statistics.
  
  
  RESULTS
  In 38 (42.7%) out of 89 patients, adverse events were documented. Most commonly, mild skin erythema at the sites of the cuffs of the device and muscle pain were encountered. In five patients (5.6%), open skin lesions (n = 2), joint pain (n = 2) or tendinopathy (n = 1) limited the continuation of the therapy with the Lokomat. No severe side-effects emerged.
  
  
  CONCLUSIONS
  Robotic assisted treadmill therapy is a safe method to enable longer periods of gait therapy in children and adolescents with gait disorders.
authors.affiliation: Ludwig-Maximilians-University of Munich, Department of Pediatric Neurology and Developmental Medicine, Munich, Germany. ingo.borggraefe@med.uni-muenchen.de
authors.forename: Ingo
authors.initials: I
authors.lastname: Borggraefe
authors.forename: Mirjam
authors.initials: M
authors.lastname: Klaiber
authors.forename: Tabea
authors.initials: T
authors.lastname: Schuler
authors.forename: Birgit
authors.initials: B
authors.lastname: Warken
authors.forename: Sebastian Alexander
authors.initials: SA
authors.lastname: Schroeder
authors.forename: Florian
authors.initials: F
authors.lastname: Heinen
authors.forename: Andreas
authors.initials: A
authors.lastname: Meyer-Heim
mesh_terms: D000293:Adolescent; D002648:Child; D004890:Erythema / Q000209:etiology* / Q000503:physiopathology; D005081:Exercise Therapy / Q000009:adverse effects* / Q000379:methods; D005260:Female; D020233:Gait Disorders, Neurologic / Q000503:physiopathology / Q000534:rehabilitation*; D006801:Humans; D007596:Joints / Q000503:physiopathology; D008297:Male; D018482:Muscle, Skeletal / Q000503:physiopathology; D010146:Pain / Q000209:etiology* / Q000503:physiopathology; D012371:Robotics / Q000295:instrumentation; D012867:Skin / Q000503:physiopathology; D052256:Tendinopathy / Q000209:etiology* / Q000503:physiopathology; D016896:Treatment Outcome