title: Advanced contrast modalities for X-ray radiology: Phase-contrast and dark-field imaging using a grating interferometer.
abstract: Here we review our recent progress in the field of X-ray dark-field and phase-contrast imaging using a grating interferometer. We describe the basic imaging principles of grating-based phase-contrast and dark-field radiography and present some exemplary results obtained for simple test objects and biological specimens. Furthermore, we discuss how phase-contrast and dark-field radiography can be combined with the concept of computed tomography, and yield highly detailed three-dimensional insights into biomedical sample. Exemplary results obtained with standard X-ray tube sources and highly brilliant synchrotron sources are presented.
authors.affiliation: Department of Physics (E17), Technische Universität München, 85748 Garching, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Bech
authors.forename: Torben H
authors.initials: TH
authors.lastname: Jensen
authors.forename: Oliver
authors.initials: O
authors.lastname: Bunk
authors.forename: Tilman
authors.initials: T
authors.lastname: Donath
authors.forename: Christian
authors.initials: C
authors.lastname: David
authors.forename: Timm
authors.initials: T
authors.lastname: Weitkamp
authors.forename: Geraldine
authors.initials: G
authors.lastname: Le Duc
authors.forename: Alberto
authors.initials: A
authors.lastname: Bravin
authors.forename: Peter
authors.initials: P
authors.lastname: Cloetens
authors.forename: Franz
authors.initials: F
authors.lastname: Pfeiffer
mesh_terms: D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging; D002645:Chickens; D003952:Diagnostic Imaging / Q000379:methods; D005557:Formaldehyde; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007368:Interferometry / Q000295:instrumentation / Q000379:methods*; D008858:Microscopy, Phase-Contrast / Q000379:methods; D011180:Postmortem Changes; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D011871:Radiology / Q000592:standards*; D051381:Rats; D017356:Synchrotrons; D014965:X-Rays
chemical_list: D005557:Formaldehyde