Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative.
High net enantiomeric excess was observed for crystal collections obtained by crystallization of the TFA salt of a configurationally stable yet racemic axially chiral amidoamine in EtOH solution with or without stirring (up to >99% ee at < or = 15% crystallization).
Sephton
Mark A
MA
Department of Chemistry, Oregon State University, Corvallis, Oregon 97331-4003, USA.
Emerson
Christopher R
CR
Zakharov
Lev N
LN
Blakemore
Paul R
PR
D000596:Amino Acids / Q000737:chemistry*; D003460:Crystallization; D008958:Models, Molecular; D013237:Stereoisomerism
D000596:Amino Acids