Fatal Clostridium difficile infection associated with vinorelbine chemotherapy: case report and literature review.
Differentiating between chemotherapy-related diarrhoea and Clostridium difficile-associated diarrhoea (CDAD) can be extremely difficult. There is increasing evidence that CDAD can be seen in patients on chemotherapy without prior antibiotic usage. We report the first case of CDAD secondary to vinorelbine chemotherapy and review the literature.
Ansari
Jawaher
J
Beatson West of Scotland Cancer Centre, Glasgow, UK. jawaher.ansari@ggc.scot.nhs.uk
Choo
Bok
B
Fernando
Indrajit
I
D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000382:microbiology; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003967:Diarrhea / Q000139:chemically induced / Q000175:diagnosis / Q000382:microbiology; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008532:Megacolon, Toxic / Q000139:chemically induced / Q000175:diagnosis / Q000382:microbiology; D008875:Middle Aged; D014747:Vinblastine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077235:Vinorelbine
D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D000077235:Vinorelbine