title: Mechanical and chemical thrombolysis of cerebral sinus thrombosis: evolution of a technique.
abstract: Cerebral sinus thrombosis, although uncommon, can be lethal if not recognized and treated quickly. Systemic heparin has become the treatment standard of care; however, some patients' conditions continue to deteriorate even while taking heparin. Endovascular techniques for thrombolysis have continued to evolve. The authors present a case of cerebral sinus thrombosis treated with a combination of mechanical and chemical intrasinus thrombolysis.
authors.affiliation: Department of Neurosurgery/Neuroradiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. kimrickert@aol.com
authors.forename: Kim L
authors.initials: KL
authors.lastname: Rickert
authors.forename: Phillip D
authors.initials: PD
authors.lastname: Purdy
authors.forename: Babu Guai
authors.initials: BG
authors.lastname: Welch
mesh_terms: D002533:Cerebral Angiography; D003131:Combined Modality Therapy; D057510:Endovascular Procedures / Q000639:trends*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D012851:Sinus Thrombosis, Intracranial / Q000628:therapy*; D013396:Suction; D015912:Thrombolytic Therapy; D000077466:Tirofiban; D016896:Treatment Outcome; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D005343:Fibrinolytic Agents; D014443:Tyrosine; D000077466:Tirofiban