Risk factors for clinical endometritis in postpartum dairy cattle.
Bacterial contamination of the uterine lumen after parturition occurs in most dairy cattle. The presence of clinical endometritis beyond three weeks post partum depends on the balance between microbes, host immunity, and other environmental or animal factors. The present study tested the hypothesis that clinical endometritis is associated with animal factors, such as retained fetal membranes, assisted calving and twins, as well as fecal contamination of the environment. The association between selected risk factors and the lactational incidence risk of clinical endometritis was examined in 293 animals from four dairy herds. Multivariate analysis was used to identify risk factors and quantify their relative risk (RR) and population attributable fraction (PAF) based on the proportion of cows exposed to each factor. The lactational incidence of clinical endometritis was 27% and significant risk factors for clinical endometritis were retained fetal membranes (RR=3.6), assisted calving (RR=1.7), stillbirth (RR=3.1), vulval angle (RR=1.3), primparity (RR=1.8), and male offspring (RR=1.5) but not the cleanliness of the environment or the animal. The highest PAF was associated with male offspring (0.6) so the use of sexed semen has the greatest potential to reduce the incidence of clinical endometritis. The dominant association between retained fetal membranes and clinical endometritis was supported by an expert panel of clinicians. The risk factors for clinical endometritis appear to be associated with trauma of the female genital tract and disruption of the physical barriers to infection rather than fecal contamination.
Potter
Timothy J
TJ
Department of Veterinary Clinical Sciences, Royal Veterinary College, North Mymms, Hatfield, UK. tpotter@rvc.ac.uk
Guitian
Javier
J
Fishwick
John
J
Gordon
Patrick J
PJ
Sheldon
I Martin
IM
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D036861:Delivery, Obstetric / Q000379:methods / Q000662:veterinary; D004716:Endometritis / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D005321:Extraembryonic Membranes; D005243:Feces; D005260:Female; D007774:Lactation; D008297:Male; D015999:Multivariate Analysis; D010298:Parity; D018457:Placenta, Retained / Q000662:veterinary; D011247:Pregnancy; D011644:Puerperal Disorders / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D012307:Risk Factors; D012737:Sex Factors; D050497:Stillbirth / Q000662:veterinary