title: Is infertility a risk factor for female sexual dysfunction? A case-control study.
abstract: OBJECTIVE
  To determine the impact of infertility on female sexual function.
  
  
  METHODS
  A case-control study.
  
  
  METHODS
  Academic infertility and gynecology practices.
  
  
  METHODS
  One hundred nineteen women with infertility and 99 healthy female controls without infertility between the ages of 18 and 45 years were included in this study.
  
  
  METHODS
  Anonymous survey and Female Sexual Function Index.
  
  
  METHODS
  Female Sexual Function Index scores, frequency of sexual intercourse and masturbation, and sex-life satisfaction.
  
  
  RESULTS
  Twenty-five percent of our control group had Female Sexual Function Index scores that put them at risk for sexual dysfunction (<26.55), whereas 40% of our patients with infertility met this criterion. Compared with the control group, the patients with infertility had significantly lower scores in the desire and arousal domains and lower frequency of intercourse and masturbation. The patients with infertility retrospectively reported a sex-life satisfaction score that was similar to that of the controls before their diagnosis, whereas their current sex-life satisfaction scores were significantly lower than those of the controls.
  
  
  CONCLUSIONS
  Women with a diagnosis of infertility were found to be at higher risk for sexual dysfunction on the basis of their Female Sexual Function Index scores compared with women without infertility. The interaction of sexual function and infertility is complex and deserves further study.
authors.affiliation: Division of Gynecologic Specialties, Stanford University Medical Center, Stanford, California 94305, USA.
authors.forename: Leah S
authors.initials: LS
authors.lastname: Millheiser
authors.forename: Amy E
authors.initials: AE
authors.lastname: Helmer
authors.forename: Rodolfo B
authors.initials: RB
authors.lastname: Quintero
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Westphal
authors.forename: Amin A
authors.initials: AA
authors.lastname: Milki
authors.forename: Ruth B
authors.initials: RB
authors.lastname: Lathi
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D011788:Quality of Life; D012107:Research Design; D012307:Risk Factors; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology / Q000209:etiology*; D011795:Surveys and Questionnaires; D055815:Young Adult