title: The first isoform-selective protein biosensor: a metallothionein potentiometric electrode.
abstract: The construction of a biosensor membrane by embedding mammalian Zn(7)-MT1 complexes as ionophores in a polysulfone matrix resulted in precise, accurate and, significantly, selective electrodes for MT1 quantification, so that the presence of other mammalian MT isoforms did not interfere in MT1 measurement.
authors.affiliation: Departament de Química, Facultat de Ciències, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Barcelona, Spain. merce.capdevila@uab.cat
authors.forename: Mercè
authors.initials: M
authors.lastname: Capdevila
authors.forename: Anna
authors.initials: A
authors.lastname: González-Bellavista
authors.forename: Maria
authors.initials: M
authors.lastname: Muñoz
authors.forename: Sílvia
authors.initials: S
authors.lastname: Atrian
authors.forename: Esteve
authors.initials: E
authors.lastname: Fàbregas
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015374:Biosensing Techniques; D004566:Electrodes; D008668:Metallothionein / Q000032:analysis* / Q000737:chemistry; D051379:Mice; D008969:Molecular Sequence Data; D011199:Potentiometry; D020033:Protein Isoforms / Q000032:analysis* / Q000737:chemistry; D017386:Sequence Homology, Amino Acid
chemical_list: D020033:Protein Isoforms; D008668:Metallothionein