title: XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments.
abstract: We present an extensible software model for the genotype and phenotype community, XGAP. Readers can download a standard XGAP (http://www.xgap.org) or auto-generate a custom version using MOLGENIS with programming interfaces to R-software and web-services or user interfaces for biologists. XGAP has simple load formats for any type of genotype, epigenotype, transcript, protein, metabolite or other phenotype data. Current functionality includes tools ranging from eQTL analysis in mouse to genome-wide association studies in humans.
authors.affiliation: Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands. m.a.swertz@rug.nl
authors.forename: Morris A
authors.initials: MA
authors.lastname: Swertz
authors.forename: K Joeri van der
authors.initials: KJ
authors.lastname: Velde
authors.forename: Bruno M
authors.initials: BM
authors.lastname: Tesson
authors.forename: Richard A
authors.initials: RA
authors.lastname: Scheltema
authors.forename: Danny
authors.initials: D
authors.lastname: Arends
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Vera
authors.forename: Rudi
authors.initials: R
authors.lastname: Alberts
authors.forename: Martijn
authors.initials: M
authors.lastname: Dijkstra
authors.forename: Paul
authors.initials: P
authors.lastname: Schofield
authors.forename: Klaus
authors.initials: K
authors.lastname: Schughart
authors.forename: John M
authors.initials: JM
authors.lastname: Hancock
authors.forename: Damian
authors.initials: D
authors.lastname: Smedley
authors.forename: Katy
authors.initials: K
authors.lastname: Wolstencroft
authors.forename: Carole
authors.initials: C
authors.lastname: Goble
authors.forename: Engbert O
authors.initials: EO
authors.lastname: de Brock
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Jones
authors.forename: Helen E
authors.initials: HE
authors.lastname: Parkinson
authors.forename: Ritsert C
authors.initials: RC
authors.lastname: Jansen
mesh_terms: D000818:Animals; D056726:Genetic Association Studies / Q000379:methods*; D023281:Genomics / Q000379:methods*; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics; D012984:Software