Combined intravenous recombinant-tissular plasminogen activator and endovascular treatment of spontaneous occlusive internal carotid dissection with tandem intracranial artery occlusion.
Internal carotid artery (ICA) dissection with tandem internal carotid and middle cerebral artery occlusion may carry a poor prognosis even if intravenous recombinant-tissular plasminogen activator is administered. A better outcome may be expected with the combination of intravenous thrombolysis and endovascular methods (stenting and thromboaspiration). This procedure was performed in 3 patients who had concurrent ICA dissection and intracerebral occlusion. Endovascular treatment was feasible and safe. All our patients had a good clinical outcome. This potential effective approach may need further validation.
Lekoubou
Alain
A
Hôpital Neurologique et Neurochirurgical P. Wertheimer, Lyon, France.
Cho
Tae-Hee
TH
Nighoghossian
Norbert
N
Kumako
Vincent
V
Derex
Laurent
L
Trouillas
Paul
P
Turjman
Francis
F
D000328:Adult; D020215:Carotid Artery, Internal, Dissection / Q000150:complications / Q000628:therapy*; D002533:Cerebral Angiography; D002548:Cerebral Revascularization / Q000379:methods*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004333:Drug Administration Routes; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000150:complications / Q000628:therapy*; D007275:Injections, Intravenous / Q000379:methods; D008297:Male; D015607:Stents; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator