Involvement of L-carnitine in cellular metabolism: beyond Acyl-CoA transport.
Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where beta-oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.
Chapela
S P
SP
Departamento de Bioquímica Humana, Facultad de Medicina, Universidad de Buenos Aires, Argentine.
Kriguer
N
N
Fernández
E H
EH
Stella
C A
CA
D000107:Acetylation; D000214:Acyl Coenzyme A / Q000378:metabolism*; D000818:Animals; D017209:Apoptosis; D001692:Biological Transport; D002331:Carnitine / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D027701:Organic Cation Transport Proteins / Q000235:genetics / Q000502:physiology; D000074058:Solute Carrier Family 22 Member 5
D000214:Acyl Coenzyme A; D027701:Organic Cation Transport Proteins; C492020:SLC22A5 protein, human; D000074058:Solute Carrier Family 22 Member 5; D002331:Carnitine