Treatment of osteosarcoma. The Scandinavian Sarcoma Group experience.
Results from four consecutive trials, conducted from 1982 by members of the Scandinavian Sarcoma Group, are reviewed. A total of 330 classical osteosarcoma patients were enrolled. In all trials chemotherapy was based on the three active drugs, methotrexate, doxorubicin and cisplatinum and for the latter trials also ifosfamide. Post-operative chemotherapy was stratified by histological response to up-front treatment.
Bruland
Øyvind S
ØS
The Norwegian Radium Hospital, University of Oslo, Oslo, N-0310, Norway. oyvind.bruland@medisin.uio.no
Bauer
Henrik
H
Alvegaard
Thor
T
Smeland
Sigbjørn
S
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000401:mortality; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000188:drug therapy* / Q000401:mortality; D011379:Prognosis