title: Topical cyclosporine-A in dry eye associated with chronic graft versus host disease.
abstract: We evaluated the efficacy and safety of topical cyclosporine-A in dry eye associated with chronic graft versus host disease (GVHD) in 8 patients. Visual acuity, fluorescein staining of cornea and conjunctiva, tear break-up time, Schirmer test results and subjective complaints were recorded. Topical cyclosporine-A might be an effective and safe treatment option in dry eye related to chronic GVHD.
authors.affiliation: Ankara University, Faculty of Medicine, Department of Ophthalmology, Dikimevi, Ankara, Turkey. renginakurt@yahoo.com
authors.forename: Rengin Aslihan
authors.initials: RA
authors.lastname: Kurt
authors.forename: Nilüfer
authors.initials: N
authors.lastname: Yalçindag
authors.forename: Huban
authors.initials: H
authors.lastname: Atilla
authors.forename: Mutlu
authors.initials: M
authors.lastname: Arat
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003228:Conjunctiva / Q000187:drug effects / Q000473:pathology; D003315:Cornea / Q000187:drug effects / Q000473:pathology; D016572:Cyclosporine / Q000008:administration & dosage*; D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis; D019337:Hematologic Neoplasms / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D012189:Retrospective Studies; D033581:Stem Cell Transplantation / Q000009:adverse effects; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine