title: Cerebral and peripheral tissue oxygenation in children supported on ECMO for cardio-respiratory failure.
abstract: Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure. Establishing, maintaining and weaning from ECMO may increase the risk for intracranial injury. We used a dual channel near infrared system to monitor cerebral and peripheral tissue oxygenation in 3 venoarterial (VA) and 1 venovenous (VV) ECMO patients undergoing manipulations in the ECMO circuit flows. Spectral analysis was performed on the oxyhaemoglobin data collected from these patients with the aim of comparing oscillations at range of frequencies appearing in the two measurement sites.
authors.affiliation: Biomedical Optics Research Laboratory, Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK. mpapa@medphys.ucl.ac.uk
authors.forename: Maria D
authors.initials: MD
authors.lastname: Papademetriou
authors.forename: Ilias
authors.initials: I
authors.lastname: Tachtsidis
authors.forename: Terence S
authors.initials: TS
authors.lastname: Leung
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Elliott
authors.forename: Aparna
authors.initials: A
authors.lastname: Hoskote
authors.forename: Clare E
authors.initials: CE
authors.lastname: Elwell
mesh_terms: D001921:Brain / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D006333:Heart Failure / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007866:Leg / Q000503:physiopathology*; D010100:Oxygen / Q000378:metabolism*; D010108:Oxyhemoglobins / Q000378:metabolism; D012131:Respiratory Insufficiency / Q000150:complications* / Q000503:physiopathology
chemical_list: D010108:Oxyhemoglobins; D010100:Oxygen