Morphogen gradients: limits to signaling or limits to measurement?
In Drosophila embryos, a concentration gradient of nuclear Dorsal protein controls pattern formation along the dorsal-ventral axis. Recent quantitative studies agree on the temporal dynamics of the gradient, but disagree on its spatial limits.
Bothma
Jacques P
JP
Biophysics Graduate Group, University of California Berkeley, Berkeley, CA 94720, USA.
Levine
Michael
M
Boettiger
Alistair
A
D000818:Animals; D004330:Drosophila / Q000196:embryology*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004625:Embryo, Nonmammalian; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D009024:Morphogenesis / Q000235:genetics; D015398:Signal Transduction
D029721:Drosophila Proteins