title: Desymmetrization of cyclohexadienones via Brønsted acid-catalyzed enantioselective oxo-Michael reaction.
abstract: Desymmetrization of cyclohexadienones via enantioselective oxo-Michael reaction catalyzed by chiral phosphoric acid to afford highly enantioenriched 1,4-dioxane and tetrahydrofuran derivatives in excellent yields has been realized. The newly established methodology allows the facile enantioselective synthesis of cleroindicins C, D, and F.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Gu
authors.forename: Zi-Qiang
authors.initials: ZQ
authors.lastname: Rong
authors.forename: Chao
authors.initials: C
authors.lastname: Zheng
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You