title: [Study on the clinicopathological characteristics and pattern of lymph node metastasis in patients with gastric remnant cancer].
abstract: OBJECTIVE
  To investigate clinicopathological characteristics and the pattern of lymph node metastasis of patients with gastric remnant cancer.
  
  
  METHODS
  The data of the clinicopathological characteristics and the pattern of lymph node metastasis in 56 patients with gastric remnant cancer treated from March 1994 to December 2008 was investigated and compared with those in 1171 patients with primary gastric cancer treated over the same period.
  
  
  RESULTS
  Fifty-six patients (4.6%) with gastric remnant cancer were enrolled in this study during the period. Compared with patients with primary gastric cancer, the age of cancer onset was older [(64.3+/-9.0) vs. (58.3+/-12.6) yrs], lymph node metastasis rate was higher (31.8% vs. 25.5%), Borrmann's classification was later and neighbor organ resection rate was higher (57.1% vs. 26.4%) in patients with gastric remnant cancer; the differences were all significant (chi2=18.800, 11.679, 9.177, 25.190; P<0.05). Patients with gastric remnant cancer who underwent lymph node dissection tended to have a higher incidence of No.10 (splenic hilar lymph node) and No.11 (splenic artery lymph node) group lymph node metastasis than those in primary gastric cancer (chi2=5.558, 6.099; P<0.05). In contrast, patients with primary gastric cancer had a higher incidence of No. 2 (left cardiac lymph node), No.3 (lesser curvature lymph node) and No.8 (common hepatic artery lymph node) group lymph node metastasis than those in gastric remnant cancer (chi2=15.508, 6.003, 4.084; P<0.05). The jejunal mesentery lymph node metastasis was 24.0% (6/25) in patients with gastric remnant cancer and the peripheral connective tissue infiltration rate was 14.3% (8/56).
  
  
  CONCLUSIONS
  It suggested that patients with gastric remnant cancer has different clinicopathologic characteristics and the pattern of lymph node metastasis from those with primary gastric cancer. D2 lymph node dissection of proximate gastric cancer and jejunal mesentery lymph node dissection should be the standard operation for these patients; but combined neighboring organ resection should be taken into consideration.
authors.affiliation: Department of Gastrointestinopancreatic Surgery, the First Affiliated Hospital of Sun Yet-San University, Guangzhou 510080, China.
authors.forename: Wu
authors.initials: W
authors.lastname: Song
authors.forename: Yu-long
authors.initials: YL
authors.lastname: He
authors.forename: Shi-rong
authors.initials: SR
authors.lastname: Cai
authors.forename: Chang-hua
authors.initials: CH
authors.lastname: Zhang
authors.forename: Dong-jie
authors.initials: DJ
authors.lastname: Yang
authors.forename: Xin-ming
authors.initials: XM
authors.lastname: Song
authors.forename: Zhao
authors.initials: Z
authors.lastname: Wang
authors.forename: Wen-hua
authors.initials: WH
authors.lastname: Zhan
mesh_terms: D017668:Age of Onset; D000368:Aged; D005260:Female; D018530:Gastric Stump; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery