Generation of site-specific and enzymatically stable conjugates of recombinant proteins with ubiquitin-like modifiers by the Cu(I)-catalyzed azide-alkyne cycloaddition.
Weikart
Nadine D
ND
Fakultät Chemie-Chemische Biologie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
Mootz
Henning D
HD
D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006801:Humans; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000737:chemistry* / Q000235:genetics; D025841:Small Ubiquitin-Related Modifier Proteins / Q000378:metabolism; D025801:Ubiquitin / Q000378:metabolism
D000480:Alkynes; D001386:Azides; D011994:Recombinant Proteins; D025841:Small Ubiquitin-Related Modifier Proteins; D025801:Ubiquitin; D003300:Copper