Carcinoid tumor of the verumontanum (colliculus seminalis) of the prostatic urethra with a coexisting prostatic adenocarcinoma: a case report.
BACKGROUND
Urethral carcinoid tumors are very rare tumors with only four cases described in the literature.


METHODS
We present the case of a 61-year-old man with a primary carcinoid tumor of the verumontanum (colliculis seminalis) portion of the prostatic urethra with a coexisting prostatic adenocarcinoma. In addition to whole mount hematoxylin and eosin staining, special immunoperoxidase staining specific for chromogranin A, neuron specific enolase, synaptophysin, pan-cytokeratin and PSA, and a special combined staining for racemase (alpha-methyl CoA) antigen and p63 antigen were performed. A review of the literature is included.A single focus of invasive prostatic adenocarcinoma was identified in the periphery of the mid-left, posterior quadrant of the prostate. Approximately 17 mm from this adenocarcinoma, within the verumontanum of the prostatic urethra, there was a 3 mm maximal dimension carcinoid tumor.


CONCLUSIONS
Based on different histological features and antigenic profiles, we concluded that the two tumors were distinct.
Smith
Maxwell
M
University of Colorado Denver, Department of Pathology, Aurora, Colorado 80045-0508, USA. Francisco.LaRosa@UCDenver.edu.
Lucia
M Scott
MS
Werahera
Priya N
PN
La Rosa
Francisco G
FG