Ionic liquid [EMIM]OAc under ultrasonic irradiation towards the first synthesis of trisubstituted imidazoles.
The ionic liquid 1-ethyl-3-methylimidazole acetate ([EMIM]OAc) was found to be a mild and effective catalyst for the efficient, one-pot, three-component synthesis of 2-aryl-4,5-diphenyl imidazoles at room temperature under ultrasonic irradiation. This procedure has many obvious advantages compared to those reported in the previous literatures, including avoiding the use of harmful catalysts, reacting at room temperature, high yields, simplicity of the methodology.
Zang
Hongjun
H
Department of Material Science and Chemistry Engineering, Tianjin Polytechnic University, Tianjin Municipal Key Laboratory of Fiber Modification and Functional Fiber, Tianjin 300160, China. chemhong@126.com
Su
Qiuhong
Q
Mo
Yingming
Y
Cheng
Bo-Wen
BW
Jun
Song
S
D007093:Imidazoles / Q000138:chemical synthesis* / Q000528:radiation effects*; D052578:Ionic Liquids / Q000737:chemistry* / Q000528:radiation effects*; D013010:Sonication
D007093:Imidazoles; D052578:Ionic Liquids