title: Estimation of optimal fiducial target registration error in the presence of heteroscedastic noise.
abstract: We study the effect of point dependent (heteroscedastic) and identically distributed anisotropic fiducial localization noise on fiducial target registration error (TRE). We derive an analytic expression, based on the concept of mechanism spatial stiffness, for predicting TRE. The accuracy of the predicted TRE is compared to simulated values where the optimal registration transformation is computed using the heteroscedastic errors in variables algorithm. The predicted values are shown to be contained by the 95% confidence intervals of the root mean square TRE obtained from the simulations.
authors.affiliation: Department of Computing Science and Engineering, York University, Toronto, ON M3J 1P3, Canada. burton@cse.yorku.ca
authors.forename: Burton
authors.initials: B
authors.lastname: Ma
authors.forename: Mehdi H
authors.initials: MH
authors.lastname: Moghari
authors.forename: Randy E
authors.initials: RE
authors.lastname: Ellis
authors.forename: Purang
authors.initials: P
authors.lastname: Abolmaesumi
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D003198:Computer Simulation; D003952:Diagnostic Imaging / Q000379:methods*; D004548:Elasticity; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D016018:Least-Squares Analysis; D015233:Models, Statistical; D009010:Monte Carlo Method; D015203:Reproducibility of Results; D025321:Surgery, Computer-Assisted / Q000379:methods*