title: Severe Kikuchi's disease responsive to immune modulation.
abstract: Kikuchi's disease, although an uncommon entity, has been increasingly reported since it was first discovered in 1972. The most common manifestation of Kikuchi's disease, cervical lymphadenopathy, has no clinically distinguishable features. Therefore, a diagnosis of Kikuchi's disease has largely been based on clinical suspicion and histopathological confirmation. We present a 15-year-old Chinese girl with severe Kikuchi's disease, whose relapsing course was only responsive to highdose steroid and intravenous immunoglobulin therapy.
authors.affiliation: Department of Paediatrics, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074.
authors.forename: D Y
authors.initials: DY
authors.lastname: Lin
authors.forename: M S
authors.initials: MS
authors.lastname: Villegas
authors.forename: P L
authors.initials: PL
authors.lastname: Tan
authors.forename: S
authors.initials: S
authors.lastname: Wang
authors.forename: L P
authors.initials: LP
authors.lastname: Shek
mesh_terms: D000293:Adolescent; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D020042:Histiocytic Necrotizing Lymphadenitis / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D056747:Immunomodulation; D007262:Infusions, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone