title: Structure, function, and evolution of the Thiomonas spp. genome.
abstract: Bacteria of the Thiomonas genus are ubiquitous in extreme environments, such as arsenic-rich acid mine drainage (AMD). The genome of one of these strains, Thiomonas sp. 3As, was sequenced, annotated, and examined, revealing specific adaptations allowing this bacterium to survive and grow in its highly toxic environment. In order to explore genomic diversity as well as genetic evolution in Thiomonas spp., a comparative genomic hybridization (CGH) approach was used on eight different strains of the Thiomonas genus, including five strains of the same species. Our results suggest that the Thiomonas genome has evolved through the gain or loss of genomic islands and that this evolution is influenced by the specific environmental conditions in which the strains live.
authors.affiliation: Génétique Moléculaire, Génomique et Microbiologie, UMR7156 CNRS and Université de Strasbourg, Strasbourg, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Arsène-Ploetze
authors.forename: Sandrine
authors.initials: S
authors.lastname: Koechler
authors.forename: Marie
authors.initials: M
authors.lastname: Marchal
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Coppée
authors.forename: Michael
authors.initials: M
authors.lastname: Chandler
authors.forename: Violaine
authors.initials: V
authors.lastname: Bonnefoy
authors.forename: Céline
authors.initials: C
authors.lastname: Brochier-Armanet
authors.forename: Mohamed
authors.initials: M
authors.lastname: Barakat
authors.forename: Valérie
authors.initials: V
authors.lastname: Barbe
authors.forename: Fabienne
authors.initials: F
authors.lastname: Battaglia-Brunet
authors.forename: Odile
authors.initials: O
authors.lastname: Bruneel
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Bryan
authors.forename: Jessica
authors.initials: J
authors.lastname: Cleiss-Arnold
authors.forename: Stéphane
authors.initials: S
authors.lastname: Cruveiller
authors.forename: Mathieu
authors.initials: M
authors.lastname: Erhardt
authors.forename: Audrey
authors.initials: A
authors.lastname: Heinrich-Salmeron
authors.forename: Florence
authors.initials: F
authors.lastname: Hommais
authors.forename: Catherine
authors.initials: C
authors.lastname: Joulian
authors.forename: Evelyne
authors.initials: E
authors.lastname: Krin
authors.forename: Aurélie
authors.initials: A
authors.lastname: Lieutaud
authors.forename: Didier
authors.initials: D
authors.lastname: Lièvremont
authors.forename: Caroline
authors.initials: C
authors.lastname: Michel
authors.forename: Daniel
authors.initials: D
authors.lastname: Muller
authors.forename: Philippe
authors.initials: P
authors.lastname: Ortet
authors.forename: Caroline
authors.initials: C
authors.lastname: Proux
authors.forename: Patricia
authors.initials: P
authors.lastname: Siguier
authors.forename: David
authors.initials: D
authors.lastname: Roche
authors.forename: Zoé
authors.initials: Z
authors.lastname: Rouy
authors.forename: Grégory
authors.initials: G
authors.lastname: Salvignol
authors.forename: Djamila
authors.initials: D
authors.lastname: Slyemi
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Talla
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Weiss
authors.forename: Jean
authors.initials: J
authors.lastname: Weissenbach
authors.forename: Claudine
authors.initials: C
authors.lastname: Médigue
authors.forename: Philippe N
authors.initials: PN
authors.lastname: Bertin
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics; D001151:Arsenic / Q000378:metabolism; D020562:Betaproteobacteria / Q000235:genetics*; D002244:Carbon / Q000378:metabolism; D055028:Comparative Genomic Hybridization; D004734:Energy Metabolism / Q000235:genetics; D004777:Environment; D019143:Evolution, Molecular; D022761:Gene Transfer, Horizontal / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics; D020131:Genes, Duplicate / Q000235:genetics; D014644:Genetic Variation; D016680:Genome, Bacterial / Q000235:genetics*; D044404:Genomic Islands / Q000235:genetics; D053858:Metabolic Networks and Pathways / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D039002:Prophages / Q000235:genetics
chemical_list: D002244:Carbon; D001151:Arsenic