title: Reconstruction of massive oncologic defects using free fillet flaps.
abstract: BACKGROUND
  Forequarter and hind-limb amputations are used with curative and palliative intent in the setting of proximal limb, thorax, or truncal malignancies. For these large defects that require a free flap, the distal portions of these limbs can be harvested as fillet flaps and represent the "spare parts" concept of surgical reconstruction.
  
  
  METHODS
  The authors performed a retrospective review of 27 patients (mean age, 51.4 years) who had undergone immediate reconstruction with free fillet extremity flaps between 1991 and 2008. Seventeen patients received preoperative radiotherapy, and 21 received preoperative chemotherapy. Resections included seven hemipelvectomies, 16 forequarter amputations, and four hindquarter amputations.
  
  
  RESULTS
  The mean defect size was 1126 cm (range, 480 to 3500 cm). All 27 flaps survived and all wounds healed. Four patients (15 percent) had complications; three patients developed partial flap necrosis and required operative débridement, and there were two episodes of flap vascular compromise. Mean follow-up time was 14 months. One patient was lost to follow-up. Eight patients (30 percent) were still alive at the end of the study. The remaining 18 patients died within 22 months of resection, for a mean survival of 7 months. There was no cancer recurrence within the flap itself. Phantom pain occurred in 11 patients. At the time of discharge, pain, tissue necrosis, and infection were improved in all patients.
  
  
  CONCLUSIONS
  The use of the fillet flap is oncologically sound, has no associated donor sites, has an acceptable incidence of major complications, and allows for a healed wound with an improvement in the quality of life.
authors.affiliation: Department of Plastic Surgery, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe BoulevardHouston, Texas 77030, USA.
authors.forename: Jon P
authors.initials: JP
authors.lastname: Ver Halen
authors.forename: Peirong
authors.initials: P
authors.lastname: Yu
authors.forename: Roman J
authors.initials: RJ
authors.lastname: Skoracki
authors.forename: David W
authors.initials: DW
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000601:surgery*; D000075202:Contraindications; D005260:Female; D051677:Histiocytoma, Malignant Fibrous / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D012509:Sarcoma / Q000601:surgery; D013524:Surgical Flaps