title: Factors associated with sustained return of spontaneous circulation in children after out-of-hospital cardiac arrest of noncardiac origin.
abstract: OBJECTIVE
  The study aimed to determine the factors predictive of sustained return of spontaneous circulation (ROSC) in children with out-of-hospital cardiac arrest (OHCA) of noncardiac origin.
  
  
  METHODS
  Eighty children were included in this retrospective study. The variables that lead to sustained ROSC and those that do not lead to sustained ROSC were analyzed. Survival analyses, including chance of achieving sustained ROSC and sum duration of ROSC, were conducted according to the duration of in-hospital cardiopulmonary resuscitation (CPR).
  
  
  RESULTS
  Etiologies of noncardiac OHCA differed significantly across different age groups (P < .001). Only 8.8% of children had initial arrest rhythms that were shockable. Predictors of sustained ROSC included the initial cardiac rhythm (P = .002), a shorter period between collapse and the first chest compression (P = .002), a shorter in-hospital CPR duration (P = .004), and prehospital CPR (P = .007). In children where ROSC was initially sustained, those with in-hospital CPR of more than 20 minutes, ROSC was sustained for less time (P < .001).
  
  
  CONCLUSIONS
  Few children with noncardiac OHCA present with shockable cardiac rhythms. Furthermore, long-term ROSC is difficult to maintain in children who receive in-hospital CPR for more than 20 minutes.
authors.affiliation: Department of Emergency Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
authors.forename: Chao-Jui
authors.initials: CJ
authors.lastname: Li
authors.forename: Chia-Te
authors.initials: CT
authors.lastname: Kung
authors.forename: Ber-Ming
authors.initials: BM
authors.lastname: Liu
authors.forename: Chu-Chung
authors.initials: CC
authors.lastname: Chou
authors.forename: Chin-Fu
authors.initials: CF
authors.lastname: Chang
authors.forename: Tung-Kung
authors.initials: TK
authors.lastname: Wu
authors.forename: Tzu-An
authors.initials: TA
authors.lastname: Liu
authors.forename: Yan-Ren
authors.initials: YR
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006323:Heart Arrest / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome