Seventeen-year observation on urinary cadmium and beta2-microglobulin in inhabitants after cessation of cadmium-exposure in Japan.
The purpose of this study was to clarify the change and relationship of urinary cadmium (Cd) and beta(2)-microglobulin (beta(2)-MG) concentrations of inhabitants in Cd-polluted areas after soil restoration. The urinary Cd and beta(2)-MG concentrations of 25 males and 28 females did not show a significant change, 22 years after the Cd-polluted soil was restored. Once exposed to Cd, it was found to remain in the body, 22 years after the Cd -polluted soil was restored. However, this did not influence renal tubular dysfunction in most of the younger generation compared with elders heavily exposed to Cd.
Sato
Reiko
R
Kanazawa University Graduate School of Medical Science, 5-11-80 Kodatsuno, Kanazawa 920-0942, Japan.
Kido
Teruhiko
T
Honda
Ryumon
R
Nishijo
Muneko
M
Nakagawa
Hideaki
H
Kobayashi
Etsuko
E
Suwazono
Yasushi
Y
D000328:Adult; D002104:Cadmium / Q000633:toxicity / Q000652:urine*; D052918:Environmental Restoration and Remediation; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007674:Kidney Diseases / Q000139:chemically induced; D007684:Kidney Tubules / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012989:Soil Pollutants / Q000633:toxicity / Q000652:urine*; D001613:beta 2-Microglobulin / Q000652:urine*
D012989:Soil Pollutants; D001613:beta 2-Microglobulin; D002104:Cadmium