Focal segmental glomerulosclerosis associated with idiopathic myelofibrosis.
A patient with idiopathic myelofibrosis with nephrotic syndrome is reported. Seven months after the initial diagnosis of myelofibrosis, the patient was presented with dyspnea, generalized edema, heavy proteinuria, massive pleural effusion, and ascites. Renal biopsy showed focal segmental glomerulosclerosis. After starting immunosuppressive therapy consisting of cyclosporine and steroids, his renal function and proteinuria improved and transfusion requirements decreased.
Kaygusuz
Isik
I
Division of Hematology, Marmara University, Istanbul, Turkey.
Koc
Mehmet
M
Arikan
Hakki
H
Adiguzel
Cafer
C
Cakalagaoglu
Fulya
F
Tuglular
Tulin F
TF
Akoglu
Emel
E
D001706:Biopsy; D003937:Diagnosis, Differential; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy