title: Coronary artery disease in patients with peripheral artery disease.
abstract: OBJECTIVE
  Peripheral artery disease (PAD) is an atherosclerotic disease associated with cardiovascular risk factors, and with high cardiovascular morbidity and mortality. This study sought to assess the prevalence of angiographic coronary artery disease (CAD), and to determine the predictive value of traditional cardiovascular risk factors on the presence of CAD in patients with PAD of the lower extremities.
  
  
  METHODS
  In total, 231 patients who presented at hospital complaining of intermittent claudication were included. All patients underwent simultaneous peripheral and cardiac angiography. Age, gender, hypertension, diabetes, smoking, and lipid values were recorded.
  
  
  RESULTS
  The coronary angiograms of 64 (28%) patients were within normal limits, and 167 (72%) patients manifested CAD. Logistic regression analysis revealed that hypertension and diabetes were independent predictors for the presence of CAD or PAD.
  
  
  CONCLUSIONS
  Aggressive treatment of cardiovascular risk factors, especially hypertension and diabetes, in PAD is critically important in reducing mortality and morbidity.
authors.affiliation: Department of Cardiology, Kosuyolu Heart and Research Hospital, Istanbul, Turkey. eksduran@yahoo.com
authors.forename: Nilüfer Ekşi
authors.initials: NE
authors.lastname: Duran
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Duran
authors.forename: Emre
authors.initials: E
authors.lastname: Gürel
authors.forename: Sebahattin
authors.initials: S
authors.lastname: Gündüz
authors.forename: Gökhan
authors.initials: G
authors.lastname: Göl
authors.forename: Murat
authors.initials: M
authors.lastname: Biteker
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozkan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D016009:Chi-Square Distribution; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007383:Intermittent Claudication / Q000000981:diagnostic imaging / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011237:Predictive Value of Tests; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology