[A role of placental macrophages in gestosis pathogenesis in women of various age].
The main aim of this work was to determinate a role of placental macrophages in aetiology of gestosis and significance of pregnant women age during this pathology. We analyzed expression of CD68 (marker of placental macrophages) in placentas of healthy women and women with gestosis from younger and older age groups. We have found that in case of gestosis the increasing expression of placental macrophages at placentas of women younger than 30 years old takes place, although at placentas of women older than 30 years old expression of macrophages remains at stably high level during normal pregnancy flow and in case of gestosis.
Lin'kova
N S
NS
Kostylev
A V
AV
Kostiuchek
I N
IN
Poliakova
V O
VO
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D015703:Antigens, CD / Q000032:analysis*; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis*; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology*; D010920:Placenta / Q000276:immunology / Q000473:pathology*; D011225:Pre-Eclampsia / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D018709:Statistics, Nonparametric; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule