[Metabolic syndrome and chronic kidney disease in a rural adult population of Hunan province, China].
OBJECTIVE
To explore the relationship between metabolic syndrome and chronic kidney disease (CKD) in a rural adult population of Hunan province.


METHODS
1953 residents (older than 18 years) from the same village were randomly selected, using a stratified, multistage sampling method. All residents were interviewed and tested for albuminuria with morning spot urine albumin to creatinine ratio (abnormal: >/= 30 mg/g), reduced renal function with estimated glomerular filtration rate by modified MDRD equation [abnormal: < 60 ml/min (1.73 m(2))]. The associations of kidney damage indicators with demographic characteristics (age, gender, smoking status), indicators on health (diabetes, hypertension) and metabolic syndrome traits were examined.


RESULTS
Eligible data of 1709 subjects were enrolled in the study. After the adjustment of age, gender and other metabolic syndrome traits, participants with metabolic syndrome had a higher prevalence of CKD (19.3% vs. 13.2%, P < 0.001) than those without the syndrome. As the number of metabolic syndrome traits increased, so did the prevalence of CKD. There seemed to be a strong and independent association between metabolic syndrome and chronic kidney disease. For participants without hypertension and diabetes, metabolic syndrome was also associated with CKD (OR value 1.733, 95%CI: 1.20 - 2.41, P = 0.004).


CONCLUSIONS
In these 1709 adults under this study from a village of southern China, metabolic syndrome seemed to be associated with CKD.
Peng
Xiang
X
Department of Nephrology, The Second Xiangya Hospital, Central South University, Changsha 410000, China.
Li
Ying
Y
Li
Jun
J
Liu
Fu-you
FY
Peng
You-ming
YM
Sun
Lin
L
Zhou
Le-tian
LT
Tang
Wen-bin
WB
He
Ya-yi
YY
Chen
Xing
X
Yang
Li-jun
LJ
Chen
Jun
J
Wu
Jing-wen
JW
Peng
Jin-ding
JD
Wang
De-jun
DJ
Yu
Ren-he
RH
D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012307:Risk Factors; D012424:Rural Population