[Incidence and prognosis of intra-and extracranial large-artery stenosis in the rural community of Beijing].
OBJECTIVE
To assess the prevalence rates of intra- and extracranial large-artery stenosis in the rural community population and its related risk to the development of stroke.


METHODS
The study subjects included 1337 residents in the rural community of Beijing. Transcranial Doppler was carried our to examine the relation between intra- and extracranial large-artery stenosis and subsequent cerebrovascular events, with a mean follow-up period of 16.7 months.


RESULTS
The incidence densities of cerebral infarction and cerebral hemorrhage in persons without cerebral large-artery stenosis were 410.6 and 351.9/100-thousand person-years, respectively. In the group with large-artery stenosis, the incidence density of cerebral infarction was 3303.7/100-thousand person-years. Data from The Fisher's Exact test showed a significant difference in the two groups (P = 0.004). Cerebral large-artery stenosis (OR = 6.593, 95%CI: 1.712 - 25.390) and smoking (OR = 8.437, 95%CI: 2.327 - 30.598) appeared to be independent risk factors to cerebral infarction.


CONCLUSIONS
Cerebral large-artery stenosis and smoking were independent risk factors to cerebral infarction.
Xing
Hai-Ying
HY
Department of Neurology, First Hospital of Peking University, Beijing 100034, China.
Gao
Hui-Zhen
HZ
Tan
Xiu-Ge
XG
Fan
Chang-Feng
CF
Gao
Shan
S
Sun
Yong-An
YA
Zhang
Hua
H
Zhong
Xian-Hua
XH
Liu
Hui-Jun
HJ
Huang
Yi-Ning
YN
D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000453:epidemiology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D003251:Constriction, Pathologic / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D020765:Intracranial Arterial Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011379:Prognosis; D012307:Risk Factors; D012423:Rural Health; D012907:Smoking / Q000009:adverse effects; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology; D017585:Ultrasonography, Doppler, Transcranial