Proxy and patients ratings on quality of life in patients with schizophrenia and bipolar disorder in Korea.
OBJECTIVE
This study aimed to assess the agreement between patient and proxy ratings of Quality of life (QoL) in patients with psychotic mental illnesses.


METHODS
The abbreviated version of the WHO quality of life scale (WHOQOL-BREF) and 36-item short-form health survey (SF-36) were administered to patient-family proxy pairs of 81 schizophrenia patients with mild symptoms and 50 euthymic bipolar disorder patients. Paired t-tests and the intraclass correlation coefficient (ICC) were used to evaluate the level of agreement between patient and proxy ratings of QoL.


RESULTS
At the group level, small standardized differences (0.0-0.3 for schizophrenia, 0.0-0.5 for bipolar disorder) between patient and proxy mean scores were found for most domains in both QoL measures. At the individual level, moderate to good agreement (ICC) was found (schizophrenia: ICC 0.4-0.7 on WHOQOL-BREF; 0.4-0.7 on SF-36; bipolar disorder: ICC 0.4-0.7 on WHOQOL-BREF; 0.6-0.7 on SF-36). The reported agreement was higher than that reported for similar measures in the psychiatric population. These results may be due to the fact that our subjects had mild clinical symptoms and frequent family interaction.


CONCLUSIONS
These findings suggest that family proxy rating of patients' QoL can be used as a reasonable estimate of the patients' QoL for stable schizophrenia and bipolar patients in Korea.
Kim
Eun Joo
EJ
Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
Song
Dong Ho
DH
Kim
Se Joo
SJ
Park
Jin Young
JY
Lee
Eun
E
Seok
Jeong Ho
JH
Jon
Duk-In
DI
Cho
Hyun-Sang
HS
D000328:Adult; D001714:Bipolar Disorder; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D019727:Proxy; D011594:Psychometrics / Q000706:statistics & numerical data*; D011788:Quality of Life; D012559:Schizophrenia; D012649:Self Concept; D013223:Statistics as Topic