title: Gold(I)-catalyzed tandem cyclization approach to tetracyclic indolines.
abstract: Two highly stereoselective cationic gold(I)-catalyzed tandem cyclization reactions of alkynylindoles are described. These reactions demonstrated a novel and general strategy to rapidly construct highly functionalized polycyclic indolines. This approach was successfully employed for a formal synthesis of the akuammiline alkaloid minfiensine.
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309, USA.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Liu
authors.forename: Wenqing
authors.initials: W
authors.lastname: Xu
authors.forename: Xiang
authors.initials: X
authors.lastname: Wang
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D050607:Organogold Compounds; C057812:indoline; D006046:Gold