title: Incidence of lobar and non-lobar spontaneous intracerebral haemorrhage in a predominantly Hispanic-Mestizo population--the PISCIS stroke project: a community-based prospective study in Iquique, Chile.
abstract: BACKGROUND
  The incidence of intracerebral haemorrhage (ICH) in Hispanics is high, especially of non-lobar ICH. Our aim was to ascertain prospectively the incidence of first-ever spontaneous ICH (SICH) stratified by localisation in a Hispanic-Mestizo population of the north of Chile.
  
  
  METHODS
  Between July 2000 and June 2002 all possible cases of ICH were ascertained from multiple overlapping sources. The cases were allocated according to localisation. Those with vascular malformations or non-identifiable localisations were excluded.
  
  
  RESULTS
  We identified a total of 69 cases of first-ever ICH. Of these, 64 (92.7%) had SICH, of which we allocated 58 cases (84%) to non-lobar or lobar localisation. The mean age was 57.3 +/- 17 years, and 62.3% of the subjects were male. The age-adjusted incidence rates were 13.8 (non-lobar) and 4.9 (lobar) per 100,000 person-years. Non-lobar SICH was more frequent in young males and lobar SICH in older women. The non-lobar-to-lobar ratio was similar to previous findings in Hispanics. Hypertension was more frequent in non-lobar SICH and in diabetes, heavy drinking and antithrombotic use in lobar SICH, but in none significantly. There was no association between localisation and prognosis.
  
  
  CONCLUSIONS
  The incidence of non-lobar SICH was high, but lower than in most non-white populations. This lower incidence could be due to a lower population prevalence of risk factors, a higher socioeconomic level in this population, or chance.
authors.affiliation: Cátedra de Neurología, Departamento de Medicina, Universidad de Valparaíso, Valparaíso, Chile. pablolavados@yahoo.com
authors.forename: Pablo M
authors.initials: PM
authors.lastname: Lavados
authors.forename: Claudio
authors.initials: C
authors.lastname: Sacks
authors.forename: Liliana
authors.initials: L
authors.lastname: Prina
authors.forename: Arturo
authors.initials: A
authors.lastname: Escobar
authors.forename: Claudia
authors.initials: C
authors.lastname: Tossi
authors.forename: Fernando
authors.initials: F
authors.lastname: Araya
authors.forename: Walter
authors.initials: W
authors.lastname: Feuerhake
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gálvez
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Salinas
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Alvarez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000145:classification / Q000453:epidemiology*; D002677:Chile / Q000453:epidemiology; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factors