title: Nocardia farcinica lung infection in a patient with cystic fibrosis: a case report.
abstract: BACKGROUND
  Respiratory tract infections are the major causes of morbidity and mortality in patients with cystic fibrosis. Nocardia are rarely implicated in these infections and few reports of the involvement of this species are found in the literature.
  
  
  METHODS
  We describe a case of lung infection followed by chronic colonization of trimethoprim and sulfamethoxazole resistant Nocardia farcinica in a patient with cystic fibrosis. The chronic colonization of this uncommon bacterium in patients with cystic fibrosis was proved using a newly developed real-time polymerase chain reaction assay, which indicates that this bacterium, despite treatment, is difficult to eradicate.
  
  
  CONCLUSIONS
  Our case report confirms that this organism can be recovered in persons with cystic fibrosis. Its eradication is necessary especially if the patient is to undergo lung transplantation.
authors.affiliation: Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), CNRS-IRD, UMR 6236, Faculté de Médecine et de Pharmacie, Université de la Méditerranée, Boulevard Jean Moulin, 13385 Marseille cedex 5, France. jean-marc.rolain@univmed.fr.
authors.forename: Fadi
authors.initials: F
authors.lastname: Bittar
authors.forename: Nathalie
authors.initials: N
authors.lastname: Stremler
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Audié
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Dubus
authors.forename: Jacques
authors.initials: J
authors.lastname: Sarles
authors.forename: Didier
authors.initials: D
authors.lastname: Raoult
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Rolain