Scar less: a review of methods of scar reduction at sites of peripheral nerve repair.
Scar formation is important for normal wound healing but proliferation of scar tissue from the epineurium in response to a nerve injury will result in impediment to the regenerating axons that need to traverse the repaired site. This article reviews the events that occur after peripheral nerve transection and the challenges that need to be addressed to reduce scarring in order to improve nerve regeneration.
Ngeow
Wei Cheong
WC
Department of Oral & Maxillofacial Medicine and Surgery, School of Clinical Dentistry, University of Sheffield, Sheffield, England. ngeowy@um.edu.my
D002921:Cicatrix / Q000517:prevention & control*; D006801:Humans; D009410:Nerve Degeneration / Q000503:physiopathology; D009416:Nerve Regeneration / Q000502:physiology*; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology*