title: Adolescent menorrhagia due to platelet function disorder.
abstract: The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%. The common conditions associated with menorrhagia include von Willebrand disease (VWD), platelet function disorders and coagulation factor deficiencies. The majority of studies, which have been conducted in the West, report VWD, as the most common inherited bleeding disorder leading to menorrhagia, whereas studies from South-East Asia have found platelet function disorder as the leading inherited bleeding disorder in women with menorrhagia. The other common conditions which can lead to increased blood loss in this age group are anovulatory bleeding and hormonal disorders. We report here three cases of adolescent menorrhagia due to platelet function disorders, along with review of literature.
authors.affiliation: Department of Obstetrics & Gynecology Unit-3, Dow University of Health Sciences & Civil Hospital Karachi.
authors.forename: Nazli
authors.initials: N
authors.lastname: Hossain
authors.forename: Tasneem
authors.initials: T
authors.lastname: Farzana
authors.forename: Nusrat Hasan
authors.initials: NH
authors.lastname: Khan
authors.forename: Tahir Sultan
authors.initials: TS
authors.lastname: Shamsi
authors.forename: Andra H
authors.initials: AH
authors.lastname: James
mesh_terms: D000293:Adolescent; D001606:Bernard-Soulier Syndrome / Q000150:complications; D025861:Blood Coagulation Disorders, Inherited / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D008595:Menorrhagia / Q000209:etiology* / Q000503:physiopathology; D013915:Thrombasthenia / Q000150:complications