title: Chikungunya virus infection during pregnancy, Reunion, France, 2006.
abstract: Mother-to-child transmission of chikungunya virus was reported during the 2005-2006 outbreak on Reunion Island, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Reunion in 2006. The study population was composed of 1,400 pregnant women (628 uninfected, 658 infected during pregnancy, 27 infected before pregnancy, and 87 infected on unknown dates). We compared pregnancy outcomes for 655 (628 + 27) women not infected during pregnancy with 658 who were infected during pregnancy. Infection occurred during the first trimester for 15% of the infected women, the second for 59%, and the third for 26%. Only hospital admission during pregnancy differed between infected and uninfected women (40% vs. 29%). Other outcomes (cesarean deliveries, obstetric hemorrhaging, preterm births, stillbirths after 22 weeks, birthweight, congenital malformations, and newborn admissions) were similar. This virus had no observable effect on pregnancy outcomes.
authors.affiliation: Centre Hospitalier Régional de la Réunion, Saint-Denis, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Fritel
authors.forename: Olivier
authors.initials: O
authors.lastname: Rollot
authors.forename: Patrick
authors.initials: P
authors.lastname: Gerardin
authors.forename: Bernard Alex
authors.initials: BA
authors.lastname: Gauzere
authors.forename: Jacques
authors.initials: J
authors.lastname: Bideault
authors.forename: Louis
authors.initials: L
authors.lastname: Lagarde
authors.forename: Barbara
authors.initials: B
authors.lastname: Dhuime
authors.forename: Eric
authors.initials: E
authors.lastname: Orvain
authors.forename: Fabrice
authors.initials: F
authors.lastname: Cuillier
authors.forename: Duksha
authors.initials: D
authors.lastname: Ramful
authors.forename: Sylvain
authors.initials: S
authors.lastname: Samperiz
authors.forename: Marie Christine
authors.initials: MC
authors.lastname: Jaffar-Bandjee
authors.forename: Alain
authors.initials: A
authors.lastname: Michault
authors.forename: Liliane
authors.initials: L
authors.lastname: Cotte
authors.forename: Monique
authors.initials: M
authors.lastname: Kaminski
authors.forename: Alain
authors.initials: A
authors.lastname: Fourmaintraux
mesh_terms: D018354:Alphavirus Infections / Q000453:epidemiology* / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood; D002646:Chikungunya virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004196:Disease Outbreaks; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000821:virology; D011256:Pregnancy Outcome; D011264:Pregnancy Trimesters; D011446:Prospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D000914:Antibodies, Viral