[Concentrations of granulocyte colony-stimulating factor in children with moyamoya disease].
OBJECTIVE
To explore the roles of granulocyte colony-stimulating factor in the pathogenesis of moyamoya disease.


METHODS
Serum G-CSF concentrations were measured using enzyme linked immunosorbent assay (ELISA) in 20 children with moyamoya disease and 20 healthy children.


RESULTS
Serum G-CSF concentration (35.7+/-10.3 pg/mL) in children with moyamoya disease was significantly higher than that in healthy controls (23.5+/-3.8 pg/mL) (p<0.01).


CONCLUSIONS
The elevated serum G-CSF concentration in children with moyamoya disease suggests that G-CSF may play an important role in the pathogenesis of moyamoya disease.
Ma
Ming-Sheng
MS
Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
Zou
Li-Ping
LP
Ding
Ying-Xue
YX
Jin
Hong
H
D002648:Child; D002675:Child, Preschool; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000097:blood* / Q000502:physiology; D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000097:blood* / Q000209:etiology; D042461:Vascular Endothelial Growth Factor A / Q000032:analysis / Q000502:physiology
D042461:Vascular Endothelial Growth Factor A; D016179:Granulocyte Colony-Stimulating Factor