Granulocytic sarcoma of the small intestine: an unusual presentation of acute myelogenous leukaemia.
Granulocytic sarcoma is an extramedullary tumour of primitive granulocytic cells. It can develop at any anatomic site and is often a forerunner to the development of acute myelogenous leukaemia. Granulocytic sarcoma of the small intestine presents with abdominal pain and obstruction. We report a case of a 17-years-old boy who presented with epigastric pain. His endoscopy revealed multiple polypoid lesions throughout the duodenum and small bowel. Histopathology and flow cytometery confirmed the diagnosis of granulocytic sarcoma associated with acute myelogenous leukaemia. To our knowledge there have been only two previous case reports of multiple granulocytic sarcomas in the small intestine, both of these were adult patients. This is the first patient in the paediatric age group with multiple granulocytic sarcomas of the small intestine.
Ghafoor
Tariq
T
Paediatric Haematology, Oncology and Bone Marrow Transplant, Bristol Royal Hospital for Children, Bristol, United Kingdom.
Zaidi
Alia
A
Al Nassir
Ibrahim
I
D000293:Adolescent; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D007414:Intestinal Neoplasms / Q000209:etiology*; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D023981:Sarcoma, Myeloid / Q000209:etiology*