title: Free breathing cardiac real-time cine MR without ECG triggering.
abstract: The increasing frequency of LV functional MRI studies demands for faster methods and for more comfort for the patient. We tested, whether real-time (RT) non ECG triggered MRI allows a considerable shortening of examination time in high reproducibility. RT and standard ECG-triggered breathhold cine MRI was acquired in 9 volunteers and 21 patients. Differences between both methods were assessed by Bland-Altman analyses including variability studies. Compared to standard cine MRI, RT decreased data acquisition time by more than the factor of ten. RT produced comparable results (e.g. EF in %: +0.67 [-5.63, 6.97]) except for a slight overestimation of LV mass. Interstudy and intraobserver variability of RT cine showed a low variability. Consequently, free-breathing RT cine proved to be a reliable and suitable tool for clinical routine and may be particularly relevant in patients with sub-optimal breath-holding ability and arrhythmia.
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany. Electronic address: beer@roentgen.uni-wuerzburg.de.
authors.forename: Meinrad
authors.initials: M
authors.lastname: Beer
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Heimo
authors.initials: H
authors.lastname: Stamm
authors.affiliation: Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Machann
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Weng
authors.affiliation: Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Jan P
authors.initials: JP
authors.lastname: Goltz
authors.affiliation: Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Breunig
authors.affiliation: Medizinische Klinik I und Poliklinik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Weidemann
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Dietbert
authors.initials: D
authors.lastname: Hahn
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Oberdürrbacherstr. 6, D-97080 Würzburg, Germany.
authors.forename: Herbert
authors.initials: H
authors.lastname: Köstler
mesh_terms: D000328:Adult; D000368:Aged; D003199:Computer Systems; D003964:Diaphragm / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*; D055815:Young Adult