Hyaline vascular-type Castleman's disease in the hilum of liver: a case report.
BACKGROUND
Castleman's disease or angiofollicular lymphoid hyperplasia is a rare benign lymph node hyperplasia usually presenting as an asymptomatic mediastinal mass in children. The disease can present at any extra thoracic site with lymphoid tissue such as retroperitoneal, mesentery, axilla, and pelvis. Hepatic localization castleman disease is very rare in children. Herein, we reported a case of Castleman's disease arising from the lymph node in hilum of liver.


METHODS
A 5 -year-old girl with chief complaint of abdominal pain for two months which exaggerated in last three days was referred to the hospital. On routine physical examination, only a generalized abdominal pain was noticed. Routine laboratory investigations and Chest X-Ray were normal. Abdominal Sonography revealed a 3.7 x 3.1 cm solid mass in the hilum of the liver. On the MRI images, a lobulated mass in the portal hepatic associated with mass effect on the portal vein was visible. Histological examination revealed expansion of mantle zone in lymphatic nodules accompanied by burnt out germinal centers. This pattern was matched with the diagnosis of the hyaline-vascular type of Castleman disease. The patient underwent a laparotomy. The patient had an uneventful postoperative course.


CONCLUSIONS
This pattern was matched with the diagnosis of the hyaline-vascular type of Castleman disease.
Karami
Hossein
H
Department of Pediatric Oncology & Hematology, Thalassemia Research Center, Mazandaran University of Medical Sciences, Booali Sina Hospital, Pasdaran Boulevard, Sari, Po Box: 48158-38477, Iran. karami_oncologist@yahoo.com.
Sahebpour
Alireza Alam
AA
Ghasemi
Maryam
M
Karami
Hasan
H
Dabirian
Mojdeh
M
Vahidshahi
Kurosh
K
Masiha
Farzad
F
Shahmohammadi
Soheila
S