New platinum and ruthenium complexes--the latest class of potential chemotherapeutic drugs--a review of recent developments in the field.
New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.
Amin
Amr
A
Department of Biology, UAE University, P.O. Box 17551, UAE. a.amin@uaeu.ac.ae
Buratovich
Michael A
MA
D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D017671:Platinum Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D017975:Ruthenium Compounds / Q000494:pharmacology* / Q000627:therapeutic use
D000970:Antineoplastic Agents; D017671:Platinum Compounds; D017975:Ruthenium Compounds