Incidence of anti-zona pellucida and anti-sperm antibodies among infertile Jordanian women and its relation to mycoplasmas.
Anti-zona-pellucida autoantibodies (AZP-Ab) and anti-sperm isoantibodies (ASA) were assessed in the cervical secretions from 73 infertile Jordanian women and 41 fertile control women using latex agglutination. Significantly more women with infertility had AZP-Ab and ASA (16.4% and 8.2% respectively) compared with fertile women (9.4% and 0%), with no relation to the etiology of infertility. Using polymerase chain reaction Mycoplasma hominis and Ureaplasma urealyticum were detected in cervical secretions of 19.2% and 13.7% of infertile women, and the presence of mycoplasma was significantly correlated with the presence of AZP-Ab and ASA.
Al-Daghistani
H I
HI
Department of Medical Allied Sciences, Zarka University College, Al-Balqa Applied University, Zarka, Jordan. hala2002dagh@yahoo.com
Fram
K M
KM
D000328:Adult; D000704:Analysis of Variance; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology*; D007518:Isoantibodies / Q000032:analysis / Q000276:immunology*; D007597:Jordan / Q000453:epidemiology; D008297:Male; D009175:Mycoplasma Infections / Q000150:complications* / Q000453:epidemiology / Q000382:microbiology; D019535:Mycoplasma hominis; D011446:Prospective Studies; D013094:Spermatozoa / Q000276:immunology*; D016869:Ureaplasma Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D016990:Ureaplasma urealyticum; D014626:Vaginal Smears; D015044:Zona Pellucida / Q000276:immunology*
D001323:Autoantibodies; D007518:Isoantibodies