title: Wound length and corticosteroid administration as risk factors for surgical-site complications following cesarean section.
abstract: OBJECTIVE
  To evaluate the effect of some specific gestational factors and other known variables associated with poor wound healing in women who delivered by cesarean section.
  
  
  METHODS
  Observational, prospective study.
  
  
  METHODS
  University Hospital of Messina.
  
  
  METHODS
  A total of 212 consecutive pregnant women at term delivering by elective cesarean section.
  
  
  METHODS
  All data regarding demographic and gestational characteristics were collected at admission. The subcutaneous tissue depth was intra-operatively measured from the fascia to the skin surface, while the incision length was measured after skin closure.
  
  
  METHODS
  Onset of wound complications such as infection, seroma, hematoma, abscess or dehiscence > 1 cm.
  
  
  RESULTS
  Body mass index (BMI) at term [odd ratio (OR) 1.2, 95%CI 1.03-1.38; p = 0.01], wound length (OR 1.03, 95%CI 1.01-1.05; p < 0.001) and corticosteroid administration (OR 3.4, 95%CI 1.5-7.9; p = 0.004) were found to be correlated with wound complications. The receiver operating characteristics curve analysis suggested a cut-off of 31.1 for the BMI at term and 166 mm for the wound length with an OR of 2.28 (95%CI 1.18-4.39; p = 0.013) and 4.3 (95%CI 2.2-8.6; p < 0.001), respectively. The multivariate logistic regression model, applied to these variables and to corticosteroid administration, showed an independent correlation (at term BMI > 31.1: OR 2.04, 1.01-4.13, p = 0.047; wound length > 166 mm: OR 4.89, 2.36-10.14, p < 0.001; corticosteroid administration: OR 3.11, 1.38-6.95, p = 0.006).
  
  
  CONCLUSIONS
  To avoid wound complications obstetricians should be careful in the administration of steroids before surgery, in the skin incision length that should be kept as short as possible and in carefully observing gestational BMI.
authors.affiliation: Department of Gynecological, Obstetrical Sciences and Reproductive Medicine, University Hospital, Messina, Italy. antonio.devivo@gmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: De Vivo
authors.forename: Alfredo
authors.initials: A
authors.lastname: Mancuso
authors.forename: Annamaria
authors.initials: A
authors.lastname: Giacobbe
authors.forename: Antonio Maria
authors.initials: AM
authors.lastname: Priolo
authors.forename: Rosanna
authors.initials: R
authors.lastname: De Dominici
authors.forename: Laura
authors.initials: L
authors.lastname: Maggio Savasta
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000009:adverse effects; D000328:Adult; D019072:Antibiotic Prophylaxis; D015992:Body Mass Index; D002585:Cesarean Section / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D016015:Logistic Models; D011247:Pregnancy; D012372:ROC Curve; D012307:Risk Factors; D013529:Surgical Wound Dehiscence / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D013536:Suture Techniques; D014945:Wound Healing / Q000502:physiology*
chemical_list: D000305:Adrenal Cortex Hormones