Structure and stereochemistry of novel ecdysteroids from the roots of Serratula wolffii.
Three new natural ecdysteroids viz. 22-dehydro-20-deoxy-ajugasterone C (1), 1-hydroxy-22-deoxy-20,21-didehydro-ecdysone (2) and 22-deoxy-20,21-didehydro-ecdysone (3) were isolated from the methanol extract of the roots of Serratula wolffii. The structures of compounds 1-3 were established by various spectroscopic techniques, including one- and two-dimensional NMR, circular dichroism and mass spectroscopic methods.
Takács
Mária
M
Department of Pharmaceutical Chemistry, Semmelweis University, Högyes Endre utca 9, H-1092 Budapest, Hungary. tmaris@freedom.hu
Simon
András
A
Liktor-Busa
Erika
E
Báthori
Mária
M
Zsila
Ferenc
F
Bikádi
Zsolt
Z
Horváth
Péter
P
Veress
Gábor
G
Gergely
András
A
Tóth
Gábor
G
D019659:Asteraceae / Q000737:chemistry*; D002942:Circular Dichroism; D026461:Ecdysteroids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D026461:Ecdysteroids