title: Water-tolerant and reusable Lewis acid catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions.
abstract: 3,4-Dihydropyrimidin-2-(1H)-ones were synthesized in high yields by a one-pot cyclocondensation of an aldehyde, a 1,3-dicarbonyl compound, and urea using copper methanesulfonate (2 mol%) as a recyclable catalyst under solvent-free conditions in short reaction time (1-2 h).
authors.affiliation: College of Chemistry and Chemical Engineering, Bohai University, Jinzhou, Liaoning, P R China. minwangzg@yahoo.com.cn
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Song
authors.forename: Heng
authors.initials: H
authors.lastname: Jiang
authors.forename: Hong
authors.initials: H
authors.lastname: Gong
mesh_terms: D000143:Acids / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D004339:Drug Compounding / Q000379:methods; D011744:Pyrimidinones / Q000138:chemical synthesis*; D012997:Solvents / Q000737:chemistry; D014508:Urea / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: C507290:3,4-dihydropyridopyrimidin-2(1H)-one; D000143:Acids; D000447:Aldehydes; D011744:Pyrimidinones; D012997:Solvents; D014867:Water; D014508:Urea