title: [Sex differences and cardiovascular drugs].
abstract: In the western world, cardiovascular disease is the leading cause of death for both sexes. These diseases show substantial differences between the sexes with respect to epidemiology, biology and clinical aspects. In recent years, more attention has been directed towards sex differences in pharmacological effects. Although both sexes are included in most pharmacological trials, the proportion of women is often too low to enable sex-specific analyses.
authors.affiliation: Institutt for samfunnsmedisin, Universitetet i Tromsø, 9037 Tromsø, Norway. maja-lisa.lochen@uit.no
authors.forename: Maja-Lisa
authors.initials: ML
authors.lastname: Løchen
authors.forename: Elena
authors.initials: E
authors.lastname: Kvan
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012727:Sex Characteristics; D012737:Sex Factors; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000924:Anticholesteremic Agents; D002317:Cardiovascular Agents; D005343:Fibrinolytic Agents; D001241:Aspirin