Transcriptional memory: mothers SET the table for daughters.
Eukaryotic gene transcription within individual cells of a population is often associated with heterogeneous pulses of gene activity. A recent study, however, shows that mothers and their daughters share similar transcriptional frequencies, and inheritance of mother's transcriptional tendencies requires methylation of histone H3 by a Set1 methyltransferase.
Peterson
Craig L
CL
Program in Molecular Medicine, 373 Plantation Street, University of Massachusetts Medical School, Worcester, MA 01605, USA. craig.peterson@umassmed.edu <craig.peterson@umassmed.edu>
D004023:Dictyostelium / Q000235:genetics / Q000378:metabolism*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D014158:Transcription, Genetic
D005656:Fungal Proteins