Nandrolone decanoate enhances the activities of cholanthrene induced glutathione-s-transferase in liver tissue of albino mice.
A concrete study is still fragmentary to correlate the effect of Nandrolone decanoate, a anabolic steroid, on the cholanthrene induced Glutathione-s-transferases (GST) activities in liver tissues. Administration of Nandrolone and 3-Methylcholanthrene in alone and combination is found to increase the activity of hepatic GST activity significantly (p< 0.01) suggesting Nandrolone as a potent inducer of GST activity.
Acharjee
Biswajit Kumar
BK
Department of Zoology, Gauhati University, Guwahati, Assam, India. biswajitacharjee79@gmail.com
Mahanta
Rita
R
Borkotoky
Aparajita
A
D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D004790:Enzyme Induction / Q000187:drug effects; D005982:Glutathione Transferase / Q000187:drug effects* / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology*; D051379:Mice; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000077603:Nandrolone Decanoate
D045930:Anabolic Agents; D008748:Methylcholanthrene; D009277:Nandrolone; D005982:Glutathione Transferase; D000077603:Nandrolone Decanoate