Relevant mouse model for human monocytic leukemia through Cre/lox-controlled myeloid-specific deletion of PTEN.
Yu
H
H
Li
Y
Y
Gao
C
C
Fabien
L
L
Jia
Y
Y
Lu
J
J
Silberstein
L E
LE
Pinkus
G S
GS
Ye
K
K
Chai
L
L
Luo
H R
HR
D000818:Animals; D001752:Blast Crisis; D002465:Cell Movement; D004195:Disease Models, Animal; D006801:Humans; D007124:Immunoenzyme Techniques; D019426:Integrases / Q000378:metabolism*; D007948:Leukemia, Monocytic, Acute / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D051379:Mice; D018345:Mice, Knockout; D022423:Myeloid Cells / Q000378:metabolism / Q000473:pathology*; D009504:Neutrophils / Q000378:metabolism / Q000473:pathology; D051059:PTEN Phosphohydrolase / Q000502:physiology*; D010766:Phosphorylation; D051057:Proto-Oncogene Proteins c-akt; D017382:Reactive Oxygen Species / Q000378:metabolism; D015996:Survival Rate
D017382:Reactive Oxygen Species; D051057:Proto-Oncogene Proteins c-akt; C045073:Cre recombinase; D019426:Integrases; D051059:PTEN Phosphohydrolase; C487757:Pten protein, mouse