title: Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates.
abstract: Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the preparation of functionalized indole derivatives.
authors.affiliation: Dipartimento di Scienze Chimiche, Università di Camerino, via S.Agostino, 1, I-62032, Camerino, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Palmieri
authors.forename: Marino
authors.initials: M
authors.lastname: Petrini
authors.forename: Rafik R
authors.initials: RR
authors.lastname: Shaikh
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D055808:Drug Discovery; D007202:Indicators and Reagents / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000473:Alkanes; D007202:Indicators and Reagents; D007211:Indoles