title: Transcranial Doppler ultrasound CO2 challenge complicated by subarachnoid hemorrhage in patient with moyamoya syndrome.
abstract: BACKGROUND
  Studies to assess the hemodynamic status of patients with moyamoya syndrome are often done to determine the need for surgical revascularization. These studies, including transcranial Doppler (TCD) ultrasonography to assess vasomotor reactivity (VMR) to CO(2), are generally considered safe.
  
  
  METHODS
  We describe a patient with moyamoya syndrome who experienced a subarachnoid hemorrhage (SAH) following TCD with CO(2) challenge.
  
  
  CONCLUSIONS
  SAH has not previously been described as a complication of CO(2) challenge in patients with moyamoya syndrome. While such complications are rare, it is important to consider the possibility of harm related to VMR testing in patients with advanced vasculopathy.
authors.affiliation: Department of Neurology, Harborview Medical Center, University of Washington School of Medicine, Seattle, USA.
authors.forename: Megan M
authors.initials: MM
authors.lastname: Donohue
authors.forename: Anne
authors.initials: A
authors.lastname: Moore
authors.forename: Dean
authors.initials: D
authors.lastname: Shibata
authors.forename: Stephanie
authors.initials: S
authors.lastname: Ebel-Caswell
authors.forename: Kyra J
authors.initials: KJ
authors.lastname: Becker
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D002245:Carbon Dioxide / Q000009:adverse effects; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D009072:Moyamoya Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D017585:Ultrasonography, Doppler, Transcranial
chemical_list: D002245:Carbon Dioxide