Crystallization of community-acquired respiratory distress syndrome toxin from Mycoplasma pneumoniae.
Community-acquired respiratory distress syndrome toxin (CARDS TX) is a 591-amino-acid protein with ADP-ribosyltransferase and vacuolating activities that damages the cells lining the respiratory tracts of patients infected with the bacterial pathogen Mycoplasma pneumoniae. Crystals of CARDS TX were grown in space group C2, with unit-cell parameters a = 191.4, b = 107.4, c = 222.1 A, beta = 90.6 degrees. A complete 2.2 A data set was obtained from a single CARDS TX crystal.
Pakhomova
Olga N
ON
Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229, USA.
Taylor
Alexander B
AB
Becker
Argentina
A
Holloway
Stephen P
SP
Kannan
T R
TR
Baseman
Joel B
JB
Hart
P John
PJ
D036002:ADP Ribose Transferases / Q000737:chemistry*; D001426:Bacterial Proteins / Q000737:chemistry*; D001427:Bacterial Toxins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D009177:Mycoplasma pneumoniae / Q000201:enzymology*; D014461:Ultracentrifugation
D001426:Bacterial Proteins; D001427:Bacterial Toxins; C546120:CARDS toxin, Mycoplasma pneumoniae; D036002:ADP Ribose Transferases