Systemic juvenile xanthogranuloma with fatal outcome.
Juvenile xanthogranuloma is a benign and self-limited disease which usually appears in the skin of children. Visceral involvement has been rarely reported, as has fatal outcome in some affected individuals. We report a case of systemic juvenile xanthogranuloma in a female newborn with mainly skin, bone marrow, and liver involvement, leading to death at the age of 2 months.
Azorín
Daniel
D
Department of Pathology, Hospital del Niño Jesús, 28009 Madrid, Spain.
Torrelo
Antonio
A
Lassaletta
Alvaro
A
de Prada
Inmaculada
I
Colmenero
Isabel
I
Contra
Trinidad
T
González-Mediero
Imelda
I
D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology; D017093:Liver Failure / Q000473:pathology*; D010198:Pancytopenia / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D014972:Xanthogranuloma, Juvenile / Q000473:pathology*