title: Advances in the preparation of porous polymer monoliths in capillaries and microfluidic chips with focus on morphological aspects.
abstract: Porous polymer monoliths have emerged as unique materials for many applications, including liquid-chromatographic analyses at an unrivaled speed, solid-phase extraction, and enzyme immobilization in capillary and microfluidic chip format. This article reviews the state of the art in the preparation of monoliths in narrow-bore capillaries and microfluidic chips and their miniaturization under conditions of spatial confinement. New developments in their preparation mainly using free radical polymerization techniques with a focus on morphological aspects in view of homogeneous porous materials are described. The suitability of monoliths for analysis of both large and small molecules is also discussed.
authors.affiliation: Institute of Polymer Chemistry, Johannes Kepler University Linz, Welser Strasse 42, 4060 Leonding, Austria. ivo.nischang@jku.at
authors.forename: Ivo
authors.initials: I
authors.lastname: Nischang
authors.forename: Oliver
authors.initials: O
authors.lastname: Brueggemann
authors.forename: Frantisek
authors.initials: F
authors.lastname: Svec