title: The 10 x '20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020.
abstract: The time has come for a global commitment to develop new antibacterial drugs. Current data document the impending disaster due to the confluence of decreasing investment in antibacterial drug research and development concomitant with the documented rapid increase in the level of resistance to currently licensed drugs. Despite the good faith efforts of many individuals, professional societies, and governmental agencies, the looming crisis has only worsened over the past decade.
authors.affiliation: Infectious Diseases Society of America, Arlington, Virginia 22209, USA.
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000191:economics / Q000494:pharmacology*; D001424:Bacterial Infections / Q000188:drug therapy*; D035843:Biomedical Research / Q000191:economics / Q000639:trends*; D055808:Drug Discovery / Q000191:economics / Q000639:trends*; D024881:Drug Resistance, Bacterial; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents