title: [DRD2/ANKK1 Taq IA polymorphism and early infant temperament].
abstract: OBJECTIVE
  To investigate whether there is an association between DRD2/ANKK1 Taq IA polymorphism and early infant temperament.
  
  
  METHODS
  DRD2/ANKK1 Taq IA polymorphism (rs1800497) was determined using polymerase chain reaction-ligase detection reaction (PCR-LDR) techniques in 149 Chinese Han infants from Changsha City. Their mothers were asked to complete the Early Infant Temperament Questionnaires (EITQ) when the infants were 1 to 4 months old (mean: 2.75 months). There were three genotypes found in these infants: C/C, T/T and C/T. The subjects were subdivided into T-carrier (CT, TT) and non-T-carrier (CC) groups for statistical analysis.
  
  
  RESULTS
  There were no differences in the temperament style distribution between the T-carrier and non-T carrier groups. There were also no statistically significant differences between the two groups in the score of the nine temperament dimensions.
  
  
  CONCLUSIONS
  DRD2/ANKK1 Taq IA polymorphism is not associated with early infant temperament.
authors.affiliation: Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.forename: Chun-Xiang
authors.initials: CX
authors.lastname: Huang
authors.forename: Pi-Xiang
authors.initials: PX
authors.lastname: Pi
authors.forename: Ai-Bin
authors.initials: AB
authors.lastname: Xia
authors.forename: Lin-Yan
authors.initials: LY
authors.lastname: Su
mesh_terms: D005838:Genotype; D006801:Humans; D007223:Infant; D011110:Polymorphism, Genetic; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D013694:Temperament
chemical_list: D017448:Receptors, Dopamine D2; C489948:ANKK1 protein, human; D017346:Protein Serine-Threonine Kinases