title: Pattern and possible contributing factors to dialysis-associated arrhythmia in young patients.
abstract: We studied dialysis-associated arrhythmia in 48 uraemic patients < 35 years on chronic haemodialysis (HD) (> 3 months). Holter findings showed only minor arrhythmia; atrial in 42% of patients and ventricular in 38%. ST-segment depression > 1 mm was observed in 58% of patients; 80% had arrhythmia, and 36% experienced anginal pain. HD caused a significant increase in QTc, QTdc and Ca2+ level, while K+ level was significantly decreased. Patients who experienced arrhythmia during HD had higher left ventricular mass and left ventricular mass index, lower post-dialysis K+ level, higher QTc and QTdc both before and after HD. They were more frequently hypertensive. ST-segment depression was significantly related to ventricular arrhythmia.
authors.affiliation: Department of Cardiovascular Medicine, Assiut University Hospital, Assiut University, Assiut, Egypt.
authors.forename: H
authors.initials: H
authors.lastname: Hasan-Ali
authors.forename: M H
authors.initials: MH
authors.lastname: Maghraby
authors.forename: E
authors.initials: E
authors.lastname: Mosad
authors.forename: A A
authors.initials: AA
authors.lastname: Abd-Elsayed
mesh_terms: D000328:Adult; D018880:Atrial Premature Complexes / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D016009:Chi-Square Distribution; D004534:Egypt / Q000453:epidemiology; D015716:Electrocardiography, Ambulatory; D005260:Female; D006785:Hospitals, University; D006801:Humans; D006973:Hypertension / Q000150:complications; D017379:Hypertrophy, Left Ventricular / Q000150:complications; D007008:Hypokalemia / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008133:Long QT Syndrome / Q000150:complications; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications; D006435:Renal Dialysis / Q000009:adverse effects*; D012307:Risk Factors; D018879:Ventricular Premature Complexes / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*