Kikuchi Fujimoto disease associated with cryptogenic organizing pneumonia: case report and literature review.
BACKGROUND
The association of Kikuchi Fujimoto disease (KFD) with cryptogenic organizing pneumonia (COP) is extremely rare. We report a case of simultaneous diagnosis of KFD and COP.


METHODS
A 33-year-old male presented with a 1-month cough illness and fever lasting for 5 days. The chest radiograph revealed double lower lobe infiltrate, which was unresponsive to antibiotics. A cervical lymph node was first found in the development of this disease. Bronchoscopy, bronchoalveolar lavage and lung biopsy established the diagnosis of COP, while a lymph node biopsy was consistent with KFD. The patient improved on steroids.


CONCLUSIONS
KFD and COP are possible part of a disease continuum, rather than separate entities.
Hua
Feng
F
Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai, 200032, PR China. fan615@yahoo.com
Zhu
Lei
L
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid; D001999:Bronchoscopy; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D013902:Radiography, Thoracic; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D013256:Steroids