Topical cyclosporine-A in dry eye associated with chronic graft versus host disease.
We evaluated the efficacy and safety of topical cyclosporine-A in dry eye associated with chronic graft versus host disease (GVHD) in 8 patients. Visual acuity, fluorescein staining of cornea and conjunctiva, tear break-up time, Schirmer test results and subjective complaints were recorded. Topical cyclosporine-A might be an effective and safe treatment option in dry eye related to chronic GVHD.
Kurt
Rengin Aslihan
RA
Ankara University, Faculty of Medicine, Department of Ophthalmology, Dikimevi, Ankara, Turkey. renginakurt@yahoo.com
Yalçindag
Nilüfer
N
Atilla
Huban
H
Arat
Mutlu
M
D000328:Adult; D002908:Chronic Disease; D003228:Conjunctiva / Q000187:drug effects / Q000473:pathology; D003315:Cornea / Q000187:drug effects / Q000473:pathology; D016572:Cyclosporine / Q000008:administration & dosage*; D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis; D019337:Hematologic Neoplasms / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D012189:Retrospective Studies; D033581:Stem Cell Transplantation / Q000009:adverse effects; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult
D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine