[Study on the dynamic change of essential components in Folium Apocyni Veneti].
OBJECTIVE
To determine the dynamic change of essential components in Folium Apocyni Veneti, and provide scientific basis for determining the best collecting time.


METHODS
The essential components of Folium Apocyni Veneti from different harvesting time were analyzed by HSGC-MS. The relative content of the components were determined with peak area normalization method, and the dynamic changes of 7 main bioactive components were determined.


RESULTS
39 constituents were separated and 38 compounds were identified. There were 21 co-containing compounds in Folium Apocyni Veneti from different harvesting time, the accumulation of which showed a regular pattern.


CONCLUSIONS
The main essential components in Folium Apocyni Veneti are the highest in the traditional harvesting time.
Song
Jian-ping
JP
Yancheng Health Vocational & Technical College, Yancheng 224006, China.
Zhang
Yue-chan
YC
Liu
Xun-hong
XH
Wang
Li-juan
LJ
D030010:Apocynum / Q000737:chemistry* / Q000254:growth & development*; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D008610:Menthol / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D039821:Monoterpenes / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D009822:Oils, Volatile / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry* / Q000254:growth & development*; D012621:Seasons; D013997:Time Factors
D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes; D004365:Drugs, Chinese Herbal; D039821:Monoterpenes; D009822:Oils, Volatile; D008610:Menthol; C016775:alpha-terpineol; C019466:menthone