title: Measurement of ophthalmodynamometric pressure with the vented-gas forced-infusion system during pars plana vitrectomy.
abstract: OBJECTIVE
  To measure ophthalmodynamometric pressure (ODP) with the vented-gas forced-infusion (VGFI) system during vitrectomy in patients with various vitreoretinal disorders and to investigate factors related to ODP.
  
  
  METHODS
  This study included 169 eyes of 169 patients undergoing pars plana vitrectomy. After core vitrectomy, the intraocular pressure was gradually raised by using the VGFI system. When the central retinal artery or its branches on the optic nerve head showed pulsations, the pressure was recorded as ODP. Diastolic blood pressure (DBP) and systolic blood pressure (SBP) were measured simultaneously with ODP. Multiple regression analysis was performed to investigate the relationship between ODP and various explanatory variables: DBP, SBP, age, presence of diabetic mellitus (DM) and hypertension (HT), body mass index, and serum total cholesterol.
  
  
  RESULTS
  ODP was 66.9 +/- 12.5 mm Hg (range, 15.5-103.7), and it correlated significantly with DBP (r = 0.60, P < 0.0001) but not with SBP (r = 0.12, P = 0.12). ODP in DM patients who had proliferative diabetic retinopathy and diabetic macular edema was lower than that in non-DM patients, whereas DBP was not significantly different between the two groups. Similar results were obtained in HT patients. Multiple regression analysis revealed that ODP had a significant correlation with DBP (P < 0.0001), presence of DM (P = 0.02), and presence of HT (P = 0.03).
  
  
  CONCLUSIONS
  VGFI is a new method of determining ODP. ODP was significantly associated with DBP and was lower in patients with DM and HT.
authors.affiliation: Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan. fumiki-o@md.tsukuba.ac.jp
authors.forename: Fumiki
authors.initials: F
authors.lastname: Okamoto
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Sugiura
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Yumi
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hiraoka
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Oshika
mesh_terms: D000388:Air; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003920:Diabetes Mellitus / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension; D007429:Intraocular Pressure / Q000502:physiology*; D008269:Macular Edema / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009884:Ophthalmodynamometry / Q000379:methods*; D012161:Retinal Artery / Q000502:physiology*; D012164:Retinal Diseases / Q000601:surgery; D013552:Swine; D014160:Transducers, Pressure; D014821:Vitrectomy
chemical_list: D002784:Cholesterol