title: Performing phase I clinical trials of anticancer agents: perspectives from within the European union and Japan.
abstract: Drug discovery and early clinical development is an international endeavor, conducted in partnership between commercial entities such as biotechnology and pharmaceutical companies and academic investigators. Although once considered quite disparate, early clinical trials requirements and conduct are largely harmonized between the European Union, Japan, and the United States, increasing the opportunities for productive commercial-academic collaborations.
authors.affiliation: The Cancer Institute, University College London, London, United Kingdom.
authors.forename: Martin D
authors.initials: MD
authors.lastname: Forster
authors.forename: Nagahiro
authors.initials: N
authors.lastname: Saijo
authors.forename: Lesley
authors.initials: L
authors.lastname: Seymour
authors.forename: Hilary
authors.initials: H
authors.lastname: Calvert
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic / Q000941:ethics / Q000592:standards* / Q000639:trends; D017277:Drug Approval / Q000331:legislation & jurisprudence*; D005062:European Union; D006801:Humans; D007564:Japan; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents