title: Vitiligo in North-Eastern China: An association between mucosal and acrofacial lesions.
abstract: Vitiligo is a mucocutaneous pigmentary disorder with worldwide distribution. Little is known about the clinical profile of vitiligo in North-eastern China. Accordingly, we reviewed 692 vitiligo out-patients from seven government hospitals in North-eastern China via a questionnaire in a multi-centre study conducted between June 2007 and June 2008, and hence characterized the epidemiology of vitiligo in North-eastern China. The mean +/- standard deviation age of onset was 23.69 +/- 13.83 years (range < 1-77 years). No gender preponderance was seen. The back was the most common site of involvement (39.6%). Vitiligo vulgaris was the predominant form (53.5%). Mucosal lesions were associated with lesions on the feet (odds ratio (OR) = 3.177, p < 0.001), hands (OR = 2.228, p < 0.01), face (OR = 2.028, p < 0.05) and neck (OR = 0.454, p < 0.05); but were not associated with chest, abdomen, waist, arms, legs or scalp lesions. Mucosal vitiligo is probably a special form of acrofacial vitiligo.
authors.affiliation: Department of Dermatology, Hospital of China Medical University, Shenyang, China.
authors.forename: Uwesu Omari
authors.initials: UO
authors.lastname: Mchepange
authors.forename: Xing-Hua
authors.initials: XH
authors.lastname: Gao
authors.forename: Yue-Yang
authors.initials: YY
authors.lastname: Liu
authors.forename: Yu-Bo
authors.initials: YB
authors.lastname: Liu
authors.forename: Lei
authors.initials: L
authors.lastname: Ma
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Hong-Duo
authors.initials: HD
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D018450:Disease Progression; D005145:Face; D005260:Female; D005528:Foot; D006225:Hand; D006306:Health Surveys; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology*; D009333:Neck; D016017:Odds Ratio; D010641:Phenotype; D018570:Risk Assessment; D012307:Risk Factors; D012867:Skin / Q000473:pathology*; D011795:Surveys and Questionnaires; D013997:Time Factors; D014820:Vitiligo / Q000145:classification / Q000453:epidemiology* / Q000208:ethnology / Q000473:pathology; D055815:Young Adult