title: Experimental infection of squirrel monkeys with nipah virus.
abstract: We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.
authors.affiliation: Institut Pasteur, Lyon, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Marianneau
authors.forename: Vanessa
authors.initials: V
authors.lastname: Guillaume
authors.forename: Thong
authors.initials: T
authors.lastname: Wong
authors.forename: Munisamy
authors.initials: M
authors.lastname: Badmanathan
authors.forename: Ren Yih
authors.initials: RY
authors.lastname: Looi
authors.forename: Severine
authors.initials: S
authors.lastname: Murri
authors.forename: Philippe
authors.initials: P
authors.lastname: Loth
authors.forename: Noel
authors.initials: N
authors.lastname: Tordo
authors.forename: Fabian
authors.initials: F
authors.lastname: Wild
authors.forename: Branka
authors.initials: B
authors.lastname: Horvat
authors.forename: Hugues
authors.initials: H
authors.lastname: Contamin
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000096:biosynthesis; D004195:Disease Models, Animal; D045464:Henipavirus Infections / Q000401:mortality / Q000503:physiopathology* / Q000821:virology; D006801:Humans; D045405:Nipah Virus / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D012367:RNA, Viral / Q000096:biosynthesis; D012453:Saimiri / Q000821:virology*
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D012367:RNA, Viral