title: Binary segmentation masks can improve intrasubject registration accuracy of bone structures in CT images.
abstract: Registration of bone structures is a common problem in medical research as well as in clinical applications. Intrasubject rigid 3D monomodality registration of segmented bone structures of CT images and multimodality registration of muMR and segmented muCT bone images were performed with the multiresolution intensity-based technique implemented in ITK. The registration results for binary volumes of interest (VOI) masks and for segmented gray value VOIs were compared. To determine the registration quality, in the monomodality case the sum of squared difference, the sum of absolute differences, and the normalized symmetric difference of binary masks and in the multimodality case Mattes mutual information were applied. The use of binary VOI masks was significantly superior to the use of gray value VOIs.
authors.affiliation: Institute for Medical Physics, University of Erlangen-Nuremberg, Henkestrasse 91, Erlangen, Germany, Oleg.Museyko@imp.uni-erlangen.de
authors.forename: Oleg
authors.initials: O
authors.lastname: Museyko
authors.forename: Fabian
authors.initials: F
authors.lastname: Eisa
authors.forename: Andreas
authors.initials: A
authors.lastname: Hess
authors.forename: Georg
authors.initials: G
authors.lastname: Schett
authors.forename: Willi A
authors.initials: WA
authors.lastname: Kalender
authors.forename: Klaus
authors.initials: K
authors.lastname: Engelke
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008875:Middle Aged