title: Use of autologous whole blood during internal limiting membrane peeling and macular hole surgery is protective for indocyanine green toxicity.
abstract: OBJECTIVE
  To compare indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling with and without autologous whole blood (WB) protection during macular hole repair surgery.
  
  
  METHODS
  We retrospectively reviewed 50 eyes with an idiopathic macular hole. Group 1 contained 22 eyes that underwent ILM peeling with WB protection and group 2 contained 28 eyes that underwent ILM peeling without WB. Anatomic and visual results were compared.
  
  
  RESULTS
  After surgery, macular hole closure was achieved in 96% of the group 1 eyes and in 93% of the group 2 eyes. The preoperative mean best-corrected visual acuity (BCVA) was logarithm of the minimum angle of resolution (logMAR) 0.95 in group 1 and logMAR 0.89 in group 2 (p = .544). The postoperative mean BCVA was logMAR 0.57 in group 1 and logMAR 0.92 in group 2 (p = .017).
  
  
  CONCLUSIONS
  Macular hole surgery protected with WB facilitates improved visual recovery in ICG-assisted ILM peeling.
authors.affiliation: Department of Ophthalmology, Chang-Gung Memorial Hospital, Keelung, Taiwan.
authors.forename: Lan-Hsin
authors.initials: LH
authors.lastname: Chuang
authors.forename: Nan-Kai
authors.initials: NK
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Yeung
authors.forename: Yen-Po
authors.initials: YP
authors.lastname: Chen
authors.forename: Yih-Shiou
authors.initials: YS
authors.lastname: Hwang
authors.forename: Wei-Chi
authors.initials: WC
authors.lastname: Wu
authors.forename: Chi-Chun
authors.initials: CC
authors.lastname: Lai
mesh_terms: D001804:Blood Transfusion, Autologous; D005260:Female; D006801:Humans; D007208:Indocyanine Green / Q000633:toxicity*; D008297:Male; D008566:Membranes / Q000473:pathology; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D012167:Retinal Perforations / Q000473:pathology / Q000601:surgery*; D055213:Retinal Pigment Epithelium / Q000473:pathology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D007208:Indocyanine Green