Surgical treatment and prognostic analysis of 93 cases of hilar cholangiocarcinoma.
OBJECTIVE
To explore the surgical treatment and prognosis of hilar cholangiocarcinoma.


METHODS
This was a retrospective study of 93 cases of hilar cholangiocarcinoma that were treated surgically at our hospital from June 1999 to June 2005. Prognostic factors were also analyzed.


RESULTS
Fifty-two cases were treated with curative resection, 21 with palliative resection, and 9 with nonoperative drainage. Eleven cases underwent palliative drainage operations. The median survive time was 31 months in the curative resection group, 13.7 months in the palliative resection group, and 11 months in the nonoperative drainage group. Patient age, serum total bilirubin, clinical type of Bismuth-Corlette, tumor differentiation, and lymph node metastases were important factors for predicting the prognosis of hilar cholangiocarcinoma.


CONCLUSIONS
Resection was the main treatment for hilar cholangiocarcinoma, and curative resection was the best way to obtain better prognosis. Age, preoperative serum total bilirubin, bismuth clinical type, tumor histopathological grading, and lymph node metastases were considered to have a significant effect on prognosis.
Zhang
Bing-Yuan
BY
Second Department of General Surgery, Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China. bingyuanzhang@126.com
Lu
Yun
Y
Dong
Qian
Q
Sun
Chuan-Dong
CD
Mu
Peng
P
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology* / Q000601:surgery*; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome