title: Malignant transformation of ectopic pancreatic cells in the duodenal wall.
abstract: Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant transformation. A few cases of neoplastic phenomena that developed from EP into the duodenal wall are described in the literature. Herein we report a case of gastric outlet obstruction due to adenocarcinoma arising from EP of the duodenal wall. The patient underwent a Whipple's procedure and had an uneventful post-operative recovery. Traditional imaging studies are often inconclusive in the definitive diagnosis, whilst endoscopic ultrasonography and guided biopsy may aid accurate pre-operative diagnosis. Diagnostic uncertainty warrants surgical exploration and if necessary extended resection is indicated.
authors.affiliation: Department of General and Emergency Surgery, San Giovanni Bosco Hospital, 10154 Turin, Italy. re.bini@libero.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Bini
authors.forename: Paolo
authors.initials: P
authors.lastname: Voghera
authors.forename: Alberto
authors.initials: A
authors.lastname: Tapparo
authors.forename: Raffaele
authors.initials: R
authors.lastname: Nunziata
authors.forename: Andrea
authors.initials: A
authors.lastname: Demarchi
authors.forename: Matteo
authors.initials: M
authors.lastname: Capocefalo
authors.forename: Renzo
authors.initials: R
authors.lastname: Leli
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D002471:Cell Transformation, Neoplastic; D002828:Choristoma / Q000150:complications*; D004379:Duodenal Neoplasms / Q000150:complications*; D017219:Gastric Outlet Obstruction / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas