Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series.
BACKGROUND
Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to treatment.


METHODS
The clinical and radiological pictures of six Mexican patients non-respondent to cysticidal treatment are presented.


CONCLUSIONS
The possible factors involved in the cysticidal non-response are discussed and hints are provided of potentially useful changes to therapeutic protocols.
Cárdenas
Graciela
G
Instituto Nacional de Neurología y Neurocirugía, México DF, México.
Carrillo-Mezo
Roger
R
Jung
Helgi
H
Sciutto
Edda
E
Hernandez
Jose Luis Soto
JL
Fleury
Agnès
A
D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use*; D000871:Anthelmintics / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008800:Mexico; D008875:Middle Aged; D020019:Neurocysticercosis / Q000188:drug therapy* / Q000473:pathology; D011223:Praziquantel / Q000627:therapeutic use*; D013346:Subarachnoid Space; D016896:Treatment Outcome
D000871:Anthelmintics; D011223:Praziquantel; D015766:Albendazole