Successful treatment of periodontal mucormycosis: report of a case and literature review.
Mucormycosis is an aggressive and potentially devastating fungal infection which typically manifests in pulmonary, rhinocerebral, or disseminated forms in patients with hematologic malignancy. Mucormycosis confined to the periodontium is uncommon, and to our knowledge only 6 cases have been reported in the English-language literature. This case report describes a patient with acute leukemia and periodontal mucormycosis. Calcofluor fluorescence microscopy is also proposed as a method for establishing a prompt diagnosis and guiding extent of intraoperative surgical debridement.
McDermott
Nancy E
NE
National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA. mcdermottn@nidcr.nih.gov
Barrett
John
J
Hipp
Jason
J
Merino
Maria J
MJ
Richard Lee
Chyi-Chia
CC
Waterman
Paige
P
Domingo
Demetrio L
DL
Walsh
Thomas J
TJ
D000208:Acute Disease; D003646:Debridement / Q000379:methods; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications* / Q000628:therapy; D010510:Periodontal Diseases / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D010519:Periodontium / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D019172:Transplantation Conditioning / Q000009:adverse effects; D016896:Treatment Outcome