title: [Incidence and prognosis of intra-and extracranial large-artery stenosis in the rural community of Beijing].
abstract: OBJECTIVE
  To assess the prevalence rates of intra- and extracranial large-artery stenosis in the rural community population and its related risk to the development of stroke.
  
  
  METHODS
  The study subjects included 1337 residents in the rural community of Beijing. Transcranial Doppler was carried our to examine the relation between intra- and extracranial large-artery stenosis and subsequent cerebrovascular events, with a mean follow-up period of 16.7 months.
  
  
  RESULTS
  The incidence densities of cerebral infarction and cerebral hemorrhage in persons without cerebral large-artery stenosis were 410.6 and 351.9/100-thousand person-years, respectively. In the group with large-artery stenosis, the incidence density of cerebral infarction was 3303.7/100-thousand person-years. Data from The Fisher's Exact test showed a significant difference in the two groups (P = 0.004). Cerebral large-artery stenosis (OR = 6.593, 95%CI: 1.712 - 25.390) and smoking (OR = 8.437, 95%CI: 2.327 - 30.598) appeared to be independent risk factors to cerebral infarction.
  
  
  CONCLUSIONS
  Cerebral large-artery stenosis and smoking were independent risk factors to cerebral infarction.
authors.affiliation: Department of Neurology, First Hospital of Peking University, Beijing 100034, China.
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Xing
authors.forename: Hui-Zhen
authors.initials: HZ
authors.lastname: Gao
authors.forename: Xiu-Ge
authors.initials: XG
authors.lastname: Tan
authors.forename: Chang-Feng
authors.initials: CF
authors.lastname: Fan
authors.forename: Shan
authors.initials: S
authors.lastname: Gao
authors.forename: Yong-An
authors.initials: YA
authors.lastname: Sun
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Xian-Hua
authors.initials: XH
authors.lastname: Zhong
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Liu
authors.forename: Yi-Ning
authors.initials: YN
authors.lastname: Huang
mesh_terms: D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000453:epidemiology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D003251:Constriction, Pathologic / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D020765:Intracranial Arterial Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011379:Prognosis; D012307:Risk Factors; D012423:Rural Health; D012907:Smoking / Q000009:adverse effects; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology; D017585:Ultrasonography, Doppler, Transcranial