title: Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization.
abstract: A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda-Grubbs second-generation catalyst.
authors.affiliation: Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan. hfuwa@bios.tohoku.ac.jp
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Fuwa
authors.forename: Kenkichi
authors.initials: K
authors.lastname: Noto
authors.forename: Makoto
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D009942:Organometallic Compounds; D011714:Pyrans