Local hyperthermia at 44 degrees C for the treatment of plantar warts: a randomized, patient-blinded, placebo-controlled trial.
There have been anecdotal reports that local hyperthermia was effective in the treatment of viral warts. We conducted a randomized, patient-blinded, placebo-controlled trial to test the effect of local hyperthermia (44 degrees C for 30 min a day for 3 consecutive days plus 2 additional days 2 weeks later) on plantar warts. By the end of 3 months, 53.57% of patients (15/28) in the treatment group and 11.54% of patients (3/26) in the control group were cured (P < .01). The effect was not influenced by patient age, duration of disease, or number or size of lesions.
Huo
Wei
W
State Key Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, China.
Gao
Xing-Hua
XH
Sun
Xiu-Ping
XP
Qi
Rui-Qun
RQ
Hong
Yuxiao
Y
Mchepange
Uwesu Omari
UO
Li
Xiao-Dong
XD
Xiao
Bi-Huan
BH
Lin
Jun-Ping
JP
Jiang
Yi
Y
Zhang
Li
L
Li
Yuan-Hong
YH
Xiao
Ting
T
Chen
John Z S
JZ
Chen
Hong-Duo
HD
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005533:Foot Dermatoses / Q000628:therapy*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016037:Single-Blind Method; D014860:Warts / Q000628:therapy*; D055815:Young Adult