title: Phenobarbital-responsive sialadenosis associated with an esophageal foreign body in a dog.
abstract: A 4-year-old Yorkshire terrier was presented for an esophageal foreign body. After removal of the foreign body, clinical signs of gagging, regurgitation, and vomiting continued unabated for >6 weeks. The dog had enlarged submandibular salivary glands that were histologically normal. Treatment with phenobarbital resulted in a rapid and dramatic resolution of clinical signs. After 3 months, the dog was weaned of phenobarbital and was free of any signs of disease 6 months later.
authors.affiliation: Departments of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Urbana, Illinois 61802, USA.
authors.forename: Chen
authors.initials: C
authors.lastname: Gilor
authors.forename: Shir
authors.initials: S
authors.lastname: Gilor
authors.forename: Thomas K
authors.initials: TK
authors.lastname: Graves
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004947:Esophagus; D018691:Excitatory Amino Acid Antagonists / Q000627:therapeutic use*; D005260:Female; D005547:Foreign Bodies / Q000150:complications / Q000601:surgery / Q000662:veterinary*; D005683:Gagging / Q000187:drug effects; D010634:Phenobarbital / Q000627:therapeutic use*; D012466:Salivary Gland Diseases / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D016896:Treatment Outcome; D014839:Vomiting / Q000209:etiology / Q000662:veterinary
chemical_list: D018691:Excitatory Amino Acid Antagonists; D010634:Phenobarbital