[DRD2/ANKK1 Taq IA polymorphism and early infant temperament].
OBJECTIVE
To investigate whether there is an association between DRD2/ANKK1 Taq IA polymorphism and early infant temperament.


METHODS
DRD2/ANKK1 Taq IA polymorphism (rs1800497) was determined using polymerase chain reaction-ligase detection reaction (PCR-LDR) techniques in 149 Chinese Han infants from Changsha City. Their mothers were asked to complete the Early Infant Temperament Questionnaires (EITQ) when the infants were 1 to 4 months old (mean: 2.75 months). There were three genotypes found in these infants: C/C, T/T and C/T. The subjects were subdivided into T-carrier (CT, TT) and non-T-carrier (CC) groups for statistical analysis.


RESULTS
There were no differences in the temperament style distribution between the T-carrier and non-T carrier groups. There were also no statistically significant differences between the two groups in the score of the nine temperament dimensions.


CONCLUSIONS
DRD2/ANKK1 Taq IA polymorphism is not associated with early infant temperament.
Ma
Jing
J
Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Huang
Chun-Xiang
CX
Pi
Pi-Xiang
PX
Xia
Ai-Bin
AB
Su
Lin-Yan
LY
D005838:Genotype; D006801:Humans; D007223:Infant; D011110:Polymorphism, Genetic; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D013694:Temperament
D017448:Receptors, Dopamine D2; C489948:ANKK1 protein, human; D017346:Protein Serine-Threonine Kinases