title: Investigation of histopathologic changes in pelviureteral junction obstruction.
abstract: OBJECTIVE
  This study aimed to determine histopathologic changes in the pelviureteral junction in children with pelviureteral junction obstruction.
  
  
  METHODS
  Seventeen pelviureteral junction specimens obtained from children were divided into two groups: pelviureteral junction obstruction (n = 7) and control (n = 10). Wall thickness of the pelviureteral junction, tunica muscularis of the pelviureteral junction, uroepithelium thickness of the pelviureteral junction, and collagen thickness of the pelviureteral junction were evaluated in resected pelviureteral junctions in children with pelviureteral junction obstruction.
  
  
  RESULTS
  The mean wall thickness of the pelviureteral junction, mean tunica muscularis of the pelviureteral junction, and uroepithelium thickness of the pelviureteral junction were not significantly higher than those in the control group. Collagen thickness values in the pelviureteral junction obstruction group were significantly higher than those in the control group.
  
  
  CONCLUSIONS
  Our data suggest that wall thickness (tunica muscularis and uroepithelium) was not significantly increased, but collagen thickness of the ureter was increased in the pelviureteral junctions of children with pelviureteral junction obstruction.
authors.affiliation: Department of Pediatric Surgery, Meram Medical School of Selcuk University, Konya, Turkey. muslimyurtcu@selcuk.edu.tr
authors.forename: Müslim
authors.initials: M
authors.lastname: Yurtçu
authors.forename: Nilifer
authors.initials: N
authors.lastname: Gürbüzer
authors.forename: Siddika
authors.initials: S
authors.lastname: Findik
authors.forename: Mustafa Cihat
authors.initials: MC
authors.lastname: Avunduk
authors.forename: Engin
authors.initials: E
authors.lastname: Günel
mesh_terms: D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013194:Staining and Labeling; D018709:Statistics, Nonparametric; D014517:Ureteral Obstruction / Q000473:pathology* / Q000601:surgery