title: HNHDb: a database on pattern based classification of HNH domains reveals functional relevance of sequence patterns and domain associations.
abstract: The HNH Database is a collection and sequence-based classification of HNH domain proteins. The database contains about 1913 HNH domain containing proteins, and is classified into 10 subsets based on the sequence pattern. Each of these subsets has unique signature sequences. We have shown a correlation between the subset combination and their domain association and function. Functional divergence of this domain may be due to the combination of these conserved patterns and the large variations in the non-conserved regions. HNHDb is freely available at http://bicmku.in:8081/hnh.
authors.affiliation: Center of Excellence in Bioinformatics, School of biotechnology, Madurai Kamaraj University, Madurai, India. alaguraj@mkustrbioinfo.in
authors.forename: Alaguraj
authors.initials: A
authors.lastname: Veluchamy
authors.forename: Sujitha
authors.initials: S
authors.lastname: Mary
authors.forename: Vishal
authors.initials: V
authors.lastname: Acharya
authors.forename: Preethi
authors.initials: P
authors.lastname: Mehta
authors.forename: Taru
authors.initials: T
authors.lastname: Deva
authors.forename: Sankaran
authors.initials: S
authors.lastname: Krishnaswamy