Polyglutamylation: the GLU that makes microtubules sticky.
The beating of cilia and flagella depends on microtubule sliding generated by dynein motors, but the interaction of these motors with their tracks is still under investigation. New evidence suggests that some dynein motors will not function properly unless their track has been modified by a specific post-translational modification.
Mitchell
David R
DR
Department of Cell and Developmental Biology, SUNY Upstate Medical University, 750 E Adams St, Syracuse, NY 13210, USA. mitcheld@upstate.edu <mitcheld@upstate.edu>
D002923:Cilia / Q000502:physiology; D004398:Dyneins / Q000502:physiology*; D005407:Flagella / Q000502:physiology; D008870:Microtubules / Q000502:physiology*; D010453:Peptide Synthases / Q000378:metabolism; D014404:Tubulin / Q000378:metabolism
D014404:Tubulin; D004398:Dyneins; D010453:Peptide Synthases; C112698:tubulin polyglutamylase