title: Rapid quantification of itraconazole-resistant Aspergillus fumigatus in air.
abstract: Solid-phase cytometry (SPC) was used to determine the total number and the number of itraconazole-resistant Aspergillus fumigatus cells in 60 air samples. Of the 570 A. fumigatus cells that were recovered, 10 (1.8%) were resistant. SPC proved more specific and rapid than culture and allowed high-troughput susceptibility testing.
authors.affiliation: Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B-9000, Ghent, Belgium.
authors.forename: Lies M E
authors.initials: LM
authors.lastname: Vanhee
authors.forename: Dana
authors.initials: D
authors.lastname: Perman
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Nelis
authors.forename: Tom
authors.initials: T
authors.lastname: Coenye
mesh_terms: D000391:Air Microbiology; D000935:Antifungal Agents / Q000494:pharmacology*; D001232:Aspergillus fumigatus / Q000187:drug effects* / Q000302:isolation & purification; D015169:Colony Count, Microbial / Q000379:methods; D025141:Drug Resistance, Fungal; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology*; D009172:Mycology / Q000379:methods*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole