[Successful treatment of a gastrointestinal stromal tumor with liver metastases in a case that tolerated imatinib administration, by radiofrequency ablation using contrast-enhanced ultrasonography].
We report a case of gastrointestinal stromal tumor (GIST) with liver metastases which was undetectable by B-mode ultrasonography, effectively treated by radiofrequency ablation using contrast-enhanced ultrasonography US. A 43-year-old woman was admitted for the treatment of 6 lesions up to 4cm in diameter, which had emerged from necrotic sites within the liver after imatinib treatment. The recurrent lesions were not detected on B-mode US, and it was difficult to perform radiofrequency ablation (RFA) treatment. Using a contrast-enhanced agent (sonazoid), the recurrent lesions were detected and treated by RFA. RFA is considered to be an effective treatment for GIST with liver metastases that tolerate imatinib administration.
Minami
Tatsuya
T
Department of Gastroenterology, Teikyo Chiba Medical Center, Japan. tminami-tky@umin.ac.jp
Sato
Shinpei
S
Watanabe
Yoshitaka
Y
Matsuda
Rie
R
Yotsuya
Satoru
S
Yamada
Akishige
A
Tanaka
Teruyuki
T
Kondo
Shintaro
S
Ebihara
Tetsuo
T
Togo
Gouichi
G
Yamazaki
Kazuto
K
Ishida
Yasuo
Y
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D017115:Catheter Ablation / Q000379:methods*; D003287:Contrast Media; D004361:Drug Tolerance; D005260:Female; D005290:Ferric Compounds; D046152:Gastrointestinal Stromal Tumors / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D000068877:Imatinib Mesylate; D007501:Iron; D008113:Liver Neoplasms / Q000556:secondary*; D010087:Oxides; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D014463:Ultrasonography
D000970:Antineoplastic Agents; D001549:Benzamides; D003287:Contrast Media; D005290:Ferric Compounds; D010087:Oxides; D010879:Piperazines; D011743:Pyrimidines; C069727:Sonazoid; D000068877:Imatinib Mesylate; D007501:Iron