Translation of biomechanics research to urogynecology.
BACKGROUND
Pelvic floor (PF) dysfunctions represent a frequent and complex problem for women. The interaction between the vagina and its supportive structures, that are designed to support increases in abdominal pressure, can be considered a biomechanical system. Recent advances in imaging technology have improved the assessment of PF structures. The aim of this paper is to review the applications of biomechanics in urogynecology.


METHODS
The available literature on biomechanics research in urogynecology was reviewed.


RESULTS
Computational models have been demonstrated to be an effective tool to investigate the effects of vaginal delivery and PF dysfunctions. Biomechanical analysis of PF tissues provides a better understanding on PF dysfunctions etiology. These studies are also important for the development of synthetic prostheses utilized in PF surgery.


CONCLUSIONS
An interdisciplinary and multidisciplinary collaborative research, involving bioengineers and clinicians, is crucial to improve clinical outcomes in patients with PF dysfunctions.
da Silva-Filho
Agnaldo Lopes
AL
Department of Gynecology and Obstetrics, Faculty of Medicine, Federal University of Minas Gerais, Avenida Professor Alfredo Balena 190, Santa Efigênia, Belo Horizonte, MG 30130-100, Brazil. agsilvaf@terra.com.br
Martins
Pedro A L S
PA
Parente
Marco P
MP
Saleme
Cristina S
CS
Roza
Thuane
T
Pinotti
Marcos
M
Mascarenhas
Teresa
T
Natal Jorge
Renato M
RM
D000818:Animals; D057005:Bioengineering; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D036861:Delivery, Obstetric / Q000009:adverse effects; D005260:Female; D006176:Gynecology; D006801:Humans; D008954:Models, Biological; D017773:Pelvic Floor / Q000503:physiopathology* / Q000601:surgery*; D011247:Pregnancy; D019736:Prostheses and Implants; D051381:Rats; D057170:Translational Research, Biomedical; D014572:Urology; D014596:Uterine Prolapse / Q000209:etiology / Q000601:surgery; D014621:Vagina / Q000503:physiopathology