Sauna lung: hypersensitivity pneumonitis due to Exophiala jeanselmei.
A 55-year-old man developed progressive cough and dyspnoea after regular attendance at a public steam bath. Hypoxaemia, diffuse pulmonary infiltrates and a predominance of lymphocytes with an increased percentage of CD8+ T cells in his bronchoalveolar lavage fluid suggested hypersensitivity pneumonitis. Microbial cultures from the steam bath room and tank identified Exophiala jeanselmei. Immunoblotting assays from the patient's serum confirmed the major antigenic stimulus. The patient recovered fully after systemic corticosteroid treatment and cessation of further exposure.
Huang
Wei-Chen
WC
Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Lu
Yin-Hsiu
YH
Lin
Zih-Gong
ZG
Su
Wen-Lin
WL
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003371:Cough / Q000382:microbiology; D004417:Dyspnea / Q000382:microbiology; D005093:Exophiala; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications* / Q000175:diagnosis; D029002:Steam Bath / Q000009:adverse effects*; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones