title: [Successful treatment of a gastrointestinal stromal tumor with liver metastases in a case that tolerated imatinib administration, by radiofrequency ablation using contrast-enhanced ultrasonography].
abstract: We report a case of gastrointestinal stromal tumor (GIST) with liver metastases which was undetectable by B-mode ultrasonography, effectively treated by radiofrequency ablation using contrast-enhanced ultrasonography US. A 43-year-old woman was admitted for the treatment of 6 lesions up to 4cm in diameter, which had emerged from necrotic sites within the liver after imatinib treatment. The recurrent lesions were not detected on B-mode US, and it was difficult to perform radiofrequency ablation (RFA) treatment. Using a contrast-enhanced agent (sonazoid), the recurrent lesions were detected and treated by RFA. RFA is considered to be an effective treatment for GIST with liver metastases that tolerate imatinib administration.
authors.affiliation: Department of Gastroenterology, Teikyo Chiba Medical Center, Japan. tminami-tky@umin.ac.jp
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Minami
authors.forename: Shinpei
authors.initials: S
authors.lastname: Sato
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Rie
authors.initials: R
authors.lastname: Matsuda
authors.forename: Satoru
authors.initials: S
authors.lastname: Yotsuya
authors.forename: Akishige
authors.initials: A
authors.lastname: Yamada
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Tanaka
authors.forename: Shintaro
authors.initials: S
authors.lastname: Kondo
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ebihara
authors.forename: Gouichi
authors.initials: G
authors.lastname: Togo
authors.forename: Kazuto
authors.initials: K
authors.lastname: Yamazaki
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ishida
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D017115:Catheter Ablation / Q000379:methods*; D003287:Contrast Media; D004361:Drug Tolerance; D005260:Female; D005290:Ferric Compounds; D046152:Gastrointestinal Stromal Tumors / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D000068877:Imatinib Mesylate; D007501:Iron; D008113:Liver Neoplasms / Q000556:secondary*; D010087:Oxides; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D003287:Contrast Media; D005290:Ferric Compounds; D010087:Oxides; D010879:Piperazines; D011743:Pyrimidines; C069727:Sonazoid; D000068877:Imatinib Mesylate; D007501:Iron