[Chemical constituents from stems of Lonicera japonica].
OBJECTIVE
To investigate the chemical constituents from the ethanol extract of the stems of Lonicera japonica.


METHODS
The constituents were isolated and purified by repeated column chromatography on silica gel, Sephadex LH-20 and MCI HP-20. Their structures were identified by phsicochemical properties and spectroscopic analysis.


RESULTS
Thirteen compounds were isolated and identified as protocatechuic acid (1), caffeic acid (2), macranthoin G (3), esculetin (4), luteolin (5), quercetin (6), apigenin (7), luteolin-7-O-beta-D-glucopyranoside (8), isorhamnetin-7-O-beta-D-glucopyranoside (9), diosmetin-7-O-beta-D-glucopyranoside (10), rhoifolin (11), lonicerin (12), hydnocarpin D (13).


CONCLUSIONS
Compound 4, 7, 9-11 were isolated from this plant for the first time, while compound 13 was first reported flavanolignan from this genus Lonicera.
Zhang
Cong
C
Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.
Yin
Zhiqi
Z
Ye
Wencai
W
Guan
Yuzhen
Y
Guo
Lian
L
Zhang
Jian
J
Shen
Wenbin
W
D047311:Luteolin / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry
D010936:Plant Extracts; D047311:Luteolin