Visualization of multiple alignments, phylogenies and gene family evolution.
Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.
Procter
James B
JB
University of Dundee, UK. j.procter@dundee.ac.uk
Thompson
Julie
J
Letunic
Ivica
I
Creevey
Chris
C
Jossinet
Fabrice
F
Barton
Geoffrey J
GJ
D000595:Amino Acid Sequence; D005075:Biological Evolution; D020407:Internet; D008969:Molecular Sequence Data; D005810:Multigene Family; D010802:Phylogeny; D011506:Proteins / Q000737:chemistry; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D011506:Proteins