Asymmetric organocatalysis with sulfones.
Asymmetric organocatalysis has become a powerful tool for the synthesis of optically active compounds. Whereas early research mainly focused on combining simple reagents as a proof-of-concept for asymmetric organocatalysis, recent investigations are directed towards extending the concept to more target- and diversity-oriented synthesis. As a result of the many transformation possibilities and their ability to generate both nucleophilic and electrophilic reaction partners, sulfones have become especially important substrates in the field of organocatalysis.
Nielsen
Martin
M
Center for Catalysis, Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark.
Jacobsen
Christian Borch
CB
Holub
Nicole
N
Paixão
Marcio Weber
MW
Jørgensen
Karl Anker
KA