Structure, function, and evolution of the Thiomonas spp. genome.
Bacteria of the Thiomonas genus are ubiquitous in extreme environments, such as arsenic-rich acid mine drainage (AMD). The genome of one of these strains, Thiomonas sp. 3As, was sequenced, annotated, and examined, revealing specific adaptations allowing this bacterium to survive and grow in its highly toxic environment. In order to explore genomic diversity as well as genetic evolution in Thiomonas spp., a comparative genomic hybridization (CGH) approach was used on eight different strains of the Thiomonas genus, including five strains of the same species. Our results suggest that the Thiomonas genome has evolved through the gain or loss of genomic islands and that this evolution is influenced by the specific environmental conditions in which the strains live.
Arsène-Ploetze
Florence
F
Génétique Moléculaire, Génomique et Microbiologie, UMR7156 CNRS and Université de Strasbourg, Strasbourg, France.
Koechler
Sandrine
S
Marchal
Marie
M
Coppée
Jean-Yves
JY
Chandler
Michael
M
Bonnefoy
Violaine
V
Brochier-Armanet
Céline
C
Barakat
Mohamed
M
Barbe
Valérie
V
Battaglia-Brunet
Fabienne
F
Bruneel
Odile
O
Bryan
Christopher G
CG
Cleiss-Arnold
Jessica
J
Cruveiller
Stéphane
S
Erhardt
Mathieu
M
Heinrich-Salmeron
Audrey
A
Hommais
Florence
F
Joulian
Catherine
C
Krin
Evelyne
E
Lieutaud
Aurélie
A
Lièvremont
Didier
D
Michel
Caroline
C
Muller
Daniel
D
Ortet
Philippe
P
Proux
Caroline
C
Siguier
Patricia
P
Roche
David
D
Rouy
Zoé
Z
Salvignol
Grégory
G
Slyemi
Djamila
D
Talla
Emmanuel
E
Weiss
Stéphanie
S
Weissenbach
Jean
J
Médigue
Claudine
C
Bertin
Philippe N
PN
D000222:Adaptation, Physiological / Q000235:genetics; D001151:Arsenic / Q000378:metabolism; D020562:Betaproteobacteria / Q000235:genetics*; D002244:Carbon / Q000378:metabolism; D055028:Comparative Genomic Hybridization; D004734:Energy Metabolism / Q000235:genetics; D004777:Environment; D019143:Evolution, Molecular; D022761:Gene Transfer, Horizontal / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics; D020131:Genes, Duplicate / Q000235:genetics; D014644:Genetic Variation; D016680:Genome, Bacterial / Q000235:genetics*; D044404:Genomic Islands / Q000235:genetics; D053858:Metabolic Networks and Pathways / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D039002:Prophages / Q000235:genetics
D002244:Carbon; D001151:Arsenic