Performance evaluation of the GlucoDr plus glucometer.
BACKGROUND
Because strict glucose control is important for reducing the complications of diabetes, the self-monitoring of blood glucose is one of the fundamental treatment modalities. Many glucometers have been developed. In the present study, we evaluated a new glucometer: GlucoDr Plus (Allmedicus, Anyang, Gyeonggi-do, Republic of Korea).


METHODS
The evaluation was performed based on Clinical and Laboratory Standards Institute guidelines. Interferences by ascorbic acid, uric acid, maltose, and acetaminophen were examined, and the performance of the unit was compared to those of six other glucometers. The effects of hematocrit, of oxygen partial pressure (PaO(2)), and of multiple users were also evaluated.


RESULTS
Within-run, between-run, between-day, and total imprecision (coefficients of variation) were 0.99-4.98%. Satisfactory linearity was found for glucose concentrations of 32.5-786.5 mg/dL (R(2) = 0.9985). A comparison with the reference laboratory method showed close concordance over the entire range of concentrations evaluated (R(2) = 0.9869). No significant effects were noted due to added interferents, hematocrit, and PaO(2).


CONCLUSIONS
The GlucoDr Plus showed acceptable performance in terms of precision and linearity. It was minimally affected by various interferents. GlucoDr Plus is suitable for the self-monitoring of blood glucose by patients with diabetes.
Ko
Dae-Hyun
DH
Department of Laboratory Medicine, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 300 Gumi-dong, Gyeonggi-do, Republic of Korea.
Lim
Soo
S
Song
Sang Hoon
SH
Choi
Sung Hee
SH
Park
Young Joo
YJ
Park
Kyoung Un
KU
Jang
Hak Chul
HC
Song
Junghan
J
D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation*; D005182:Flavin-Adenine Dinucleotide / Q000737:chemistry; D042843:Glucose 1-Dehydrogenase / Q000737:chemistry; D006400:Hematocrit; D006801:Humans; D010100:Oxygen / Q000097:blood / Q000737:chemistry; D011934:Reagent Strips
D001786:Blood Glucose; D011934:Reagent Strips; D005182:Flavin-Adenine Dinucleotide; D042843:Glucose 1-Dehydrogenase; D010100:Oxygen