title: Local hyperthermia at 44 degrees C for the treatment of plantar warts: a randomized, patient-blinded, placebo-controlled trial.
abstract: There have been anecdotal reports that local hyperthermia was effective in the treatment of viral warts. We conducted a randomized, patient-blinded, placebo-controlled trial to test the effect of local hyperthermia (44 degrees C for 30 min a day for 3 consecutive days plus 2 additional days 2 weeks later) on plantar warts. By the end of 3 months, 53.57% of patients (15/28) in the treatment group and 11.54% of patients (3/26) in the control group were cured (P < .01). The effect was not influenced by patient age, duration of disease, or number or size of lesions.
authors.affiliation: State Key Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huo
authors.forename: Xing-Hua
authors.initials: XH
authors.lastname: Gao
authors.forename: Xiu-Ping
authors.initials: XP
authors.lastname: Sun
authors.forename: Rui-Qun
authors.initials: RQ
authors.lastname: Qi
authors.forename: Yuxiao
authors.initials: Y
authors.lastname: Hong
authors.forename: Uwesu Omari
authors.initials: UO
authors.lastname: Mchepange
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Li
authors.forename: Bi-Huan
authors.initials: BH
authors.lastname: Xiao
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Lin
authors.forename: Yi
authors.initials: Y
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Yuan-Hong
authors.initials: YH
authors.lastname: Li
authors.forename: Ting
authors.initials: T
authors.lastname: Xiao
authors.forename: John Z S
authors.initials: JZ
authors.lastname: Chen
authors.forename: Hong-Duo
authors.initials: HD
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005533:Foot Dermatoses / Q000628:therapy*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016037:Single-Blind Method; D014860:Warts / Q000628:therapy*; D055815:Young Adult