title: Italian appeal court: a genetic predisposition to commit murder?
abstract: A few months ago, the controversial debate on connection between genetic variants and antisocial behaviour gained renewed prominence after the sentence of an Italian judge who decided to further reduce the prison sentence of a person convicted of murder by 1 year--from 9 to 8 years--because he was found to be a carrier of a few genetic variants thought to be associated with a predisposition to aggressiveness. We discuss the social implication of this view, the lack of evidence of the clinical utility of this test, and in particular the risks of offering susceptibility testing in the context of legal proceedings.
authors.affiliation: Clinical Genetics Unit, Galliera Hospital, Genova, Italy. forzanof@galliera.it
authors.forename: Francesca
authors.initials: F
authors.lastname: Forzano
authors.forename: Pascal
authors.initials: P
authors.lastname: Borry
authors.forename: Anne
authors.initials: A
authors.lastname: Cambon-Thomsen
authors.forename: Shirley V
authors.initials: SV
authors.lastname: Hodgson
authors.forename: Aad
authors.initials: A
authors.lastname: Tibben
authors.forename: Petrus
authors.initials: P
authors.lastname: de Vries
authors.forename: Carla
authors.initials: C
authors.lastname: van El
authors.forename: Martina
authors.initials: M
authors.lastname: Cornel
mesh_terms: D000328:Adult; D019317:Evidence-Based Medicine; D020022:Genetic Predisposition to Disease; D006708:Homicide / Q000331:legislation & jurisprudence* / Q000523:psychology*; D006801:Humans; D007558:Italy; D033222:Judicial Role; D008297:Male; D012941:Social Responsibility