Amide-to-ester substitution allows fine-tuning of the cyclopeptide conformational ensemble.
Cupido
Tommaso
T
Institute for Research in Biomedicine (IRB), Barcelona Science Park (PCB) and CIBER-BBN Networking Centre on Bioengineering, Biomaterials and Nanomedicine, PCB Baldiri Reixac 10, 08028 Barcelona, Spain. tommaso.cupido@irbbarcelona.org
Spengler
Jan
J
Ruiz-Rodriguez
Javier
J
Adan
Jaume
J
Mitjans
Francesc
F
Piulats
Jaume
J
Albericio
Fernando
F
D000577:Amides / Q000737:chemistry*; D002448:Cell Adhesion; D002460:Cell Line; D004952:Esters; D006801:Humans; D016023:Integrins / Q000037:antagonists & inhibitors / Q000378:metabolism; D056004:Molecular Dynamics Simulation; D009842:Oligopeptides / Q000737:chemistry; D010456:Peptides, Cyclic / Q000737:chemistry*; D017434:Protein Structure, Tertiary
D000577:Amides; D004952:Esters; D016023:Integrins; D009842:Oligopeptides; D010456:Peptides, Cyclic; C047981:arginyl-glycyl-aspartic acid