title: Biochemical basis of the amyloid diseases.
abstract: Amyloidosis is a heterogeneous group of diseases characterized by normally soluble proteins deposited extracellularly in an abnormally folded, insoluble fibrillar form. This can lead to organ impairment and premature death. This article discusses the pathogenesis, classification system and means of diagnosis of the amyloid diseases.
authors.affiliation: UCL Medical School, Royal Free Hospital Campus, London.
authors.forename: Simon D J
authors.initials: SD
authors.lastname: Gibbs
authors.forename: Philip N
authors.initials: PN
authors.lastname: Hawkins
mesh_terms: D000682:Amyloid / Q000378:metabolism*; D000686:Amyloidosis / Q000145:classification / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000378:metabolism; D007150:Immunohistochemistry; D009154:Mutation
chemical_list: D000682:Amyloid; D007147:Immunoglobulin Light Chains