Ontogeny of Cl- homeostasis in mouse hypoglossal nucleus.
We tested the immunoreactivity of KCC2 using KCC2 antibody in the developmental mouse medulla. Age-dependent changes in immunoreactivity were remarkable in the hypoglossal nucleus, and interestingly, the immunoreactivity in the hypoglossal nucleus relative to the dorsal vagal nucleus at P0 appeared to be higher than that of P7. Thus Cl(-) homeostasis in the hypoglossal nucleus might be differentially regulated in the developmental stage.
Okabe
Akihito
A
Division of Physiome, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. okabe@hyo-med.ac.jp
Arata
Akiko
A
Oku
Yoshitaka
Y
Takayama
Chitoshi
C
Fukuda
Atsuo
A
D000818:Animals; D000831:Animals, Newborn; D002712:Chlorides / Q000378:metabolism*; D005786:Gene Expression Regulation; D006706:Homeostasis; D007002:Hypoglossal Nerve / Q000166:cytology* / Q000378:metabolism / Q000502:physiology; D007150:Immunohistochemistry; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D021381:Protein Transport; D028021:Sodium-Potassium-Chloride Symporters / Q000235:genetics / Q000378:metabolism
D002712:Chlorides; D028021:Sodium-Potassium-Chloride Symporters