Extraction of rutin from Flos Sophorae Immaturus with an aqueous 1-butyl-3-methylimidazolium chloride solution.
The study presented in this paper concerns the extractability of rutin into an aqueous 1-butyl-3-methylimidazolium chloride (BMIM-Cl) solution. The effects of the concentrations of BMIM-Cl, amounts of Flos Sophorae Immaturus (FSI), extraction temperature and time on the rutin yield were examined. Under optimized extraction conditions, the rutin yield obtained by using aqueous BMIM-Cl corresponded to that obtained by using methanol. A newly established extraction method, followed by HPLC with ultraviolet detection, was applied to FSI samples with good recoveries and high repeatability.
Huang
Jianlin
J
College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China. huangjl@hubu.edu.cn
Xie
Wenjie
W
D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007887:Fabaceae / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D010946:Plants, Medicinal; D012431:Rutin / Q000032:analysis*; D012996:Solutions; D014867:Water / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D007093:Imidazoles; D012996:Solutions; D014867:Water; C502841:1-butyl-3-methylimidazolium chloride; D012431:Rutin