title: [New approaches in coronary microcirculation].
abstract: The last decades, coronary microcirculation has become a very important territory because of its role in coronary circulation physiology and pathophysiology. Only its implication in coronary artery disease was known at the beginning, but subsequently its role in many others diseases was shown. The nontraditional pathophysiological construct sustains that myocardial microcirculatory dysfunction is the primary event, and the atherosclerotic plaque rupture or erosion is the secondary event. In some instances, the coronary microvascular dysfunction may be an epiphenomena, an important marker of risk or even a cause, thus becoming therapeutic target.
authors.affiliation: Facultatea de Medicină, Clinica de Cardiologie a Institutului de Boli Cardiovasculare "Profesor C. C. Iliescu", Universitatea de Medicină si Farmacie "C. Davila" Bucureşti.
authors.forename: Carmen
authors.initials: C
authors.lastname: Ginghină
authors.forename: Magdalena
authors.initials: M
authors.lastname: Patriche
authors.forename: R
authors.initials: R
authors.lastname: Chreih
authors.forename: B A
authors.initials: BA
authors.lastname: Popescu
authors.forename: D
authors.initials: D
authors.lastname: Deleanu
mesh_terms: D003287:Contrast Media; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D003326:Coronary Circulation; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D003328:Coronary Thrombosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D018618:Echocardiography, Doppler, Color / Q000379:methods; D004562:Electrocardiography; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008833:Microcirculation; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D049268:Positron-Emission Tomography / Q000379:methods; D012307:Risk Factors; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media