title: Role of ischemic preconditioning in liver transplant: a review of literature.
abstract: Interruption of blood flow and subsequent organ reperfusion lead to significant tissue damage. This well-studied phenomenon is recognized as ischemia/reperfusion injury. Ischemic preconditioning refers to a mechanism in which a prior, short, ischemic period induces some protection against a subsequent prolonged ischemic and reperfusion damage. The mechanisms involved in ischemic preconditioning and its applications for clinical and basic research are discussed in this paper.
authors.affiliation: Department of Surgery and Liver Transplantation, University of Pernambuco School of Medicine, Oswaldo Cruz University Hospital, Recife, Brazil. igormacedo1@hotmail.com
authors.forename: Francisco Igor Bulcão
authors.initials: FI
authors.lastname: Macedo
authors.forename: Luiz Eduardo Correia
authors.initials: LE
authors.lastname: Miranda
mesh_terms: D000818:Animals; D006801:Humans; D019194:Ischemic Preconditioning / Q000379:methods*; D016031:Liver Transplantation / Q000502:physiology*; D023421:Models, Animal; D018384:Oxidative Stress / Q000502:physiology; D015427:Reperfusion Injury / Q000503:physiopathology / Q000517:prevention & control*