ATP-dependent proteases in biogenesis and maintenance of plant mitochondria.
ATP-dependent proteases from three families have been identified experimentally in Arabidopsis mitochondria: four FtsH proteases (AtFtsH3, AtFtsH4, AtFtsH10, and AtFtsH11), two Lon proteases (AtLon1 and AtLon4), and one Clp protease (AtClpP2 with regulatory subunit AtClpX). In this review we discuss their submitochondrial localization, expression profiles and proposed functions, with special emphasis on their impact on plant growth and development. The best characterized plant mitochondrial ATP-dependent proteases are AtLon1 and AtFtsH4. It has been proposed that AtLon1 is necessary for proper mitochondrial biogenesis during seedling establishment, whereas AtFtsH4 is involved in maintaining mitochondrial homeostasis late in rosette development under short-day photoperiod.
Janska
Hanna
H
Department of Biotechnology, University of Wroclaw, 51-148 Wroclaw, Poland. Janska@ibmb.uni.wroc.pl
Piechota
Janusz
J
Kwasniak
Malgorzata
M
D049069:ATP-Dependent Proteases / Q000235:genetics / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D049071:Endopeptidase Clp / Q000235:genetics / Q000378:metabolism; D005816:Genetic Complementation Test; D008928:Mitochondria / Q000378:metabolism*; D008954:Models, Biological; D063245:Plant Development; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D049070:Protease La / Q000235:genetics / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism
D029681:Arabidopsis Proteins; D010940:Plant Proteins; D049069:ATP-Dependent Proteases; D049070:Protease La; D049071:Endopeptidase Clp