title: Onychomadesis: a rare side-effect of valproic acid medication?
abstract: Valproic acid (VPA) is frequently used as an antiepileptic drug. Several side effects are known. We report on a child with onychomadesis as a possible side-effect of treatment with VPA. Normal nail growth was observed after stopping VPA. The pathomechanism of onychomadesis due to VPA treatment remains unclear.
authors.affiliation: Paediatric Neurology, University Children's Hospital of Zurich, CH-8032Zurich, Switzerland. andrea.poretti@kispi.uzh.ch
authors.forename: Andrea
authors.initials: A
authors.lastname: Poretti
authors.forename: Ulrich
authors.initials: U
authors.lastname: Lips
authors.forename: Marco
authors.initials: M
authors.lastname: Belvedere
authors.forename: Bernhard
authors.initials: B
authors.lastname: Schmitt
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects*; D002675:Child, Preschool; D004831:Epilepsies, Myoclonic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000139:chemically induced*; D009262:Nails / Q000187:drug effects* / Q000254:growth & development; D014635:Valproic Acid / Q000009:adverse effects*
chemical_list: D000927:Anticonvulsants; D014635:Valproic Acid