Prevalence and preventability of adverse drug events in a teaching hospital: a cross-sectional study.
We determined the prevalence of adverse drug events (ADEs) in a general teaching hospital in Rabat, Morocco. We performed a 5-day cross-sectional study of hospital departments recruiting inpatients and outpatients. Among the 1390 patients surveyed, 59 (4.2%) experienced at least 1 ADE and for 20 patients (1.4%) the ADE was responsible for hospitalization or prolongation of hospitalization. The ADE was classified as serious in 28 patients. Of the total of 76 ADEs, 10 (13.2%) were categorized as preventable; 6 of these occurred during the treatment monitoring phase. Patients who experienced an ADE were more likely to be women, to be younger (< 30 years) and to be hospitalized in medical departments.
Benkirane
R
R
Moroccan Pharmacovigilance Centre, Rabat, Morocco. r_benkirane@yahoo.fr
Pariente
A
A
Achour
S
S
Ouammi
L
L
Azzouzi
A
A
Soulaymani
R
R
D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D016903:Drug Monitoring; D064420:Drug-Related Side Effects and Adverse Reactions / Q000139:chemically induced / Q000453:epidemiology / Q000517:prevention & control; D005260:Female; D006769:Hospitals, General / Q000706:statistics & numerical data; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008508:Medication Errors / Q000401:mortality / Q000517:prevention & control / Q000706:statistics & numerical data; D008875:Middle Aged; D009017:Morbidity; D009018:Morocco / Q000453:epidemiology; D017891:Pharmacoepidemiology; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric