Arterial thrombosis associated with adjuvant chemotherapy for breast cancer: a case report.
OBJECTIVE
To report a case of arterial thrombosis in a 63-year-old female undergoing treatment with multiagent chemotherapy for breast cancer. An overview of the prevalence and pathogenesis of the disorder, clinical diagnosis, and treatment are discussed.


METHODS
Case report, diagnostic evidence, and scientific literature.


CONCLUSIONS
Arterial thrombosis is an extremely rare complication of multichemotherapy treatment of breast cancer. Although the risk of arterial thromboembolism appears to be low, it can have devastating complications that result in significant morbidities and, sometimes, death.


CONCLUSIONS
As the risk of arterial thrombosis is low, many healthcare providers may not be aware of this potentially serious complication. Thrombosis prophylaxis should be considered for patients with risk factors. In cases where arterial thrombosis occurs, immediate thrombolitic therapy or operative intervention should be considered.
Department of Medical Oncology, City of Hope, National Medical Center and Beckman Research Institute, Duarte, California 91010, USA. lbourdeanu@apu.edu
Laura
L
Bourdeanu
Thehang
T
Luu
D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001241:Aspirin / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000451:nursing; D018275:Carcinoma, Lobular / Q000188:drug therapy* / Q000451:nursing; D017024:Chemotherapy, Adjuvant; D017128:Embolectomy; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009722:Nurse Practitioners; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D013923:Thromboembolism / Q000139:chemically induced* / Q000188:drug therapy / Q000601:surgery
D000925:Anticoagulants; D000970:Antineoplastic Agents; D010975:Platelet Aggregation Inhibitors; D006493:Heparin; D001241:Aspirin