What is an immunological synapse?
Immunological synapses (IS) are emerging as highly organized 3D structures -formed by surface and cytoplasmic signalling and cytoskeletal molecules - that assemble at the zone of contact between a T cell and an antigen presenting cell (APC). The IS control functions that allow APC and T cells modulate the immune response.
Rodríguez-Fernández
José Luis
JL
Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. rodrifer@cib.csic.es
Riol-Blanco
Lorena
L
Delgado-Martín
Cristina
C
D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D002450:Cell Communication / Q000276:immunology; D003598:Cytoskeletal Proteins / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology; D006801:Humans; D054992:Immunological Synapses / Q000502:physiology*; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology
D003598:Cytoskeletal Proteins