Genome-wide DNA demethylation in mammals.
The cytidine deaminase AID and elongator-complex proteins contribute to the extensive removal of DNA methylation in mammalian primordial germ cells and in the paternal pronucleus of the zygote.
Sanz
Lionel A
LA
Institute of Molecular Genetics, CNRS UMR-5535 and University of Montpellier, 1919 route de Mende, Montpellier, France.
Kota
Satya K
SK
Feil
Robert
R
D000818:Animals; D003564:Cytidine Deaminase / Q000378:metabolism*; D019175:DNA Methylation / Q000235:genetics / Q000502:physiology*; D016678:Genome / Q000235:genetics*; D005854:Germ Cells / Q000378:metabolism; D008322:Mammals / Q000235:genetics*; D013045:Species Specificity; D015027:Zebrafish / Q000235:genetics*; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
D000098830:AICDA (Activation-Induced Cytidine Deaminase); D003564:Cytidine Deaminase