Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.
The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1-3). The structures of these compounds were determined to be (19R, 23R)-5beta, 19-epoxy-19-methoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (1), (23R)-5beta, 19-epoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (2), and (19R)-5beta, 19-epoxy-19,25-dihydroxycucurbita-6,23(E)-diene-3beta-ol 3-O-beta-D-glucopyranoside (3), by chemical and spectroscopic methods.
Nguyen
Xuan Nhiem
XN
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Phan
Van Kiem
VK
Chau
Van Minh
VM
Ninh
Khac Ban
KB
Nguyen
Xuan Cuong
XC
Le
Minh Ha
MH
Bui
Huu Tai
HT
Tran
Hong Quang
HQ
Nguyen
Huu Tung
HT
Kim
Young Ho
YH
D002236:Carbohydrate Conformation; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D029777:Momordica charantia / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane