Molecular bio-motors in living cells.
The final goal of our group is to establish the missing link between chemical reaction and mechanical event in molecular motors. To achieve this, we have developed advanced versions of conventional optical microscopes and applied them into single-molecule techniques. In this chapter we present two studies: one is about the kinesin-microtubule system and the other F(1)-ATPase. These techniques are applicable to other molecular machines, hopefully in more sophisticated ways, and we hope to investigate this in future studies.
Department of Physics, Gakushuin University, Mejiro, Toshima-ku, Tokyo, 171-8588, Japan. takayuki.nishizaka@gakushuin.ac.jp
Takayuki
T
Nishizaka
D002470:Cell Survival; D002477:Cells / Q000166:cytology* / Q000378:metabolism*; D057054:Molecular Imaging; D020409:Molecular Motor Proteins / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary; D021122:Protein Subunits / Q000737:chemistry / Q000378:metabolism
D020409:Molecular Motor Proteins; D021122:Protein Subunits