CwpFM (EntFM) is a Bacillus cereus potential cell wall peptidase implicated in adhesion, biofilm formation, and virulence.
Bacillus cereus EntFM displays an NlpC/P60 domain, characteristic of cell wall peptidases. The protein is involved in bacterial shape, motility, adhesion to epithelial cells, biofilm formation, vacuolization of macrophages, and virulence. These data provide new information on this, so far, poorly studied toxin and suggest that this protein is a cell wall peptidase, which we propose to rename CwpFM.
INRA, Unité MICALIS UMR-1319, Equipe GME, La Minière, 78285 Guyancourt, France.
Seav-Ly
SL
Tran
Elisabeth
E
Guillemet
Michel
M
Gohar
Didier
D
Lereclus
Nalini
N
Ramarao
D000818:Animals; D001409:Bacillus cereus / Q000201:enzymology* / Q000254:growth & development / Q000472:pathogenicity*; D001422:Bacterial Adhesion / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D018441:Biofilms / Q000254:growth & development*; D002460:Cell Line; D002473:Cell Wall / Q000201:enzymology*; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D009036:Moths; D010447:Peptide Hydrolases / Q000235:genetics / Q000378:metabolism*; D014774:Virulence / Q000235:genetics / Q000502:physiology*
D001426:Bacterial Proteins; D010447:Peptide Hydrolases