Volume of blood suctioned during vacuum-assisted breast biopsy predicts later hematoma formation.
BACKGROUND
To evaluate whether the volume of blood suctioned during vacuum-assisted breast biopsy (VABB) is associated with hematoma formation and progression, patient's age and histology of the lesion.


RESULTS
177 women underwent VABB according to standardized protocol. The volume of blood suctioned and hematoma formation were noted at the end of the procedure, as did the subsequent development and progression of hematoma. First- and second-order logistic regression was performed, where appropriate. Cases with hematoma presented with greater volume of blood suctioned (63.8 +/- 44.7 cc vs. 17.2 +/- 32.9 cc; p < 0.001, Mann-Whitney-Wilcoxon test for independent samples, MWW); the likelihood of hematoma formation was increasing till a volume equal to 82.6 cc, at which the second-order approach predicts a maximum. The volume of blood suctioned was positively associated with the duration of the procedure (Spearman's rho = 0.417, p < 0.001); accordingly, hematoma formation was also positively associated with the latter (p = 0.004, MWW). The volume of blood suctioned was not associated with patients' age, menopausal status and histopathological diagnosis.


CONCLUSIONS
The likelihood of hematoma is increasing along with increasing amount of blood suctioned, reaching a plateau approximately at 80 cc of blood lost.
Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens; 114, Vas Sofias Ave, Athens 116 27, Greece. gzografo@med.uoa.gr.
Flora
F
Zagouri
Theodoros N
TN
Sergentanis
Philip
P
Domeyer
Dimosthenis
D
Chrysikos
Georgia
G
Giannakopoulou
Nikolaos V
NV
Michalopoulos
Panagiotis
P
Safioleas
Ioannis
I
Flessas
Effrosyni
E
Panopoulou
Garifallia
G
Bletsa
George C
GC
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