Antimicrobial susceptibilities of health care-associated and community-associated strains of methicillin-resistant Staphylococcus aureus from hospitalized patients in Canada, 1995 to 2008.
We determined the in vitro antimicrobial susceptibilities of 7,942 methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from patients hospitalized in 48 Canadian hospitals from 1995 to 2008. Regional variations in susceptibilities were identified. The dissemination of community-associated strains in Canada appears to have contributed to increased susceptibility of MRSA to several non-beta-lactam antimicrobial agents in the past decade. Reduced susceptibility to glycopeptides was not identified.
Simor
Andrew E
AE
Department of Microbiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. andrew.simor@sunnybrook.ca
Louie
Lisa
L
Watt
Christine
C
Gravel
Denise
D
Mulvey
Michael R
MR
Campbell
Jennifer
J
McGeer
Allison
A
Bryce
Elizabeth
E
Loeb
Mark
M
Matlow
Anne
A
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002170:Canada / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000188:drug therapy* / Q000453:epidemiology; D003428:Cross Infection / Q000188:drug therapy* / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D011634:Public Health / Q000706:statistics & numerical data; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000453:epidemiology
D000900:Anti-Bacterial Agents