Fluid-induced coagulopathy: does the type of fluid make a difference?
Crystalloid and colloid solutions are used for resuscitation of the critically ill. One set of options, widely used today, are different preparations of hydroxyethyl starch (HES). However, the safety of HES regarding impairment of blood coagulation remains incompletely elucidated, a circumstance that limits its clinical use. Understanding mechanisms and potential differences between low-molecular and low-substituted HES and other HES solutions seems clinically relevant.
Gernot
G
Marx
Tobias
T
Schuerholz
D001778:Blood Coagulation Disorders / Q000209:etiology*; D005440:Fluid Therapy / Q000009:adverse effects*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000009:adverse effects* / Q000737:chemistry; D012996:Solutions
D006895:Hydroxyethyl Starch Derivatives; D012996:Solutions