Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds.
Catalytic amination: The title reaction demonstrates the use of aryl carboxylates as suitable electrophilic coupling substrates in catalytic amination reactions. N-heterocyclic carbene ligands and NaOtBu promote the amination of aryl pivalates through the cleavage of normally unreactive aryl carbon-oxygen bonds (see scheme; cod=cyclooctadiene).
Frontier Research Base for Global Young Researchers, Graduate School of Engineering, Osaka University, Suita, Japan.
Toshiaki
T
Shimasaki
Mamoru
M
Tobisu
Naoto
N
Chatani
D000586:Amination; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D010421:Pentanoic Acids / Q000737:chemistry*
D006571:Heterocyclic Compounds; D010421:Pentanoic Acids; D009532:Nickel; C005566:pivalic acid