TiSGeD: a database for tissue-specific genes.
The tissue-specific genes are a group of genes whose function and expression are preferred in one or several tissues/cell types. Identification of these genes helps better understanding of tissue-gene relationship, etiology and discovery of novel tissue-specific drug targets. In this study, a statistical method is introduced to detect tissue-specific genes from more than 123 125 gene expression profiles over 107 human tissues, 67 mouse tissues and 30 rat tissues. As a result, a novel subject-specialized repository, namely the tissue-specific genes database (TiSGeD), is developed to represent the analyzed results. Auxiliary information of tissue-specific genes was also collected from biomedical literatures.


BACKGROUND
http://bioinf.xmu.edu.cn/databases/TiSGeD/index.html.
Xiao
Sheng-Jian
SJ
Key Laboratory for Cell Biology and Tumor Cell Engineering, the Ministry of Education of China, School of Life Sciences, Fujian, P R China.
Zhang
Chi
C
Zou
Quan
Q
Ji
Zhi-Liang
ZL
D000465:Algorithms; D000818:Animals; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D015233:Models, Statistical; D020411:Oligonucleotide Array Sequence Analysis; D051381:Rats