Fast whole-brain 4D contrast-enhanced MR angiography with velocity encoding using undersampled radial acquisition and highly constrained projection reconstruction: image-quality assessment in volunteer subjects.
We report on the image quality obtained by using fast contrast-enhanced whole-brain 4D radial MRA with 0.75-second temporal resolution, isotropic submillimeter spatial resolution, and velocity encoding (HYPRFlow). Images generated by HYPR-LR by using the velocity-encoded data as the constraining image were of diagnostic quality. In addition, we demonstrate that measurements of shear stress within the middle cerebral artery can be derived from the high-resolution 3D velocity data.
Wu
Y
Y
Department of Medical Physics, University of Wisconsin, Madison, 53705, USA. yijingwu@wisc.edu
Chang
W
W
Johnson
K M
KM
Velikina
J
J
Rowley
H
H
Mistretta
C
C
Turski
P
P
D000328:Adult; D000465:Algorithms; D001921:Brain / Q000098:blood supply*; D002533:Cerebral Angiography / Q000379:methods; D002536:Cerebral Arteries / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D055815:Young Adult