[Field evaluation of gold-immunochromatographic assay for diagnosis of vivax malaria].
OBJECTIVE
To evaluate a gold-immunochromatographic assay (GICA) for malaria diagnosis in an endemic area of vivax malaria.


METHODS
Blood samples were collected from febrile patients in 5 township-hospitals of Mengcheng County, Anhui Province, between September and October 2008. The samples were examined by GICA and microscopy under double blind condition and the results were compared.


RESULTS
Among 292 blood samples, 181 were found P. vivax-positive by microscopy, and 163 were positive by GICA. Altogether, the coincidence of the two methods stood for 92.8% (271/292), including 108 negatives and 163 positives. 21 samples with discrepancy covered 18 microscopy positive but GICA negative, 3 microscopy negative but GICA positive. The GICA positive rate in patients with a parasitaemia of > 1,000 parasites/microl, 100-1,000 parasites/microl, and < 100 parasites/microl was 93.5% (115/123), 86.0% (43/50), and 62.5% (5/8), respectively.


CONCLUSIONS
GICA is a useful diagnosis method for endemic area of vivax malaria.
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Jun-Yun
JY
Wang
Jian-Jun
JJ
Wang
Feng
F
Shi
Xian
X
Xu
Yue-Tao
YT
Yang
Chun-Hua
CH
Gao
Xiang
X
Zheng
Jun
J
Ge
Lin-Hua
LH
Tang
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D017979:Gold Colloid; D006801:Humans; D007118:Immunoassay; D007223:Infant; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010966:Plasmodium vivax; D055815:Young Adult
D017979:Gold Colloid