Swim-up procedure selects spermatozoa with longer telomere length.
Telomere length and sperm DNA fragmentation were determined in sperm samples from 27 patients, using a quantitative PCR (Q-PCR) assay and the Sperm Chromatin Dispersion (SCD) test, respectively. Comparisons of the samples before and after swim-up processing demonstrated that this procedure selects a sperm population with longer average telomere size and lower frequency of sperm cells with fragmented DNA.
INIBIC-Complejo Hospitalario Universitario A Coruña, Unidad de Genética, As Xubias, 84, 15006 A Coruña, Spain.
Rebeca
R
Santiso
María
M
Tamayo
Jaime
J
Gosálvez
Marcos
M
Meseguer
Nicolás
N
Garrido
José Luis
JL
Fernández
D053938:DNA Fragmentation; D006801:Humans; D008297:Male; D013081:Sperm Motility; D013094:Spermatozoa / Q000502:physiology*; D016615:Telomere / Q000502:physiology*