[Comparative study of induction time using propofol bolus injection in elderly patients].
BACKGROUND
We studied the induction time using propofol bolus injection in elderly patients.


METHODS
In 55 patients ranging in ages from 31 to 91, ASA1 or 2, scheduled for surgery under general anesthesia propofol 2 mg x kg(-1) was administered by a bolus injection via iv cannula with 2% lidocaine 0.5 mg x kg(-1). The time to reaching the BIS value of 50 from the administration (t50 second) was compared. Patients were devided to two group: those aged 32-74 year-old (group A) and those aged 75-91 year-old (group B). We compared t50 second and TP between the two groups.


RESULTS
The correlations between t50 second and the age as well as t50 second and TP, were examined. There were significant differences between the two groups in t50 sec and TP. No critical hemodynamic changes were observed during anesthesia induction.


CONCLUSIONS
Prolonged anesthesia induction time was observed with the advancing ages.
Division of Anesthesiology, Higashi-Yamato Hospital, Tokyo 207-0014.
Satoko
S
Miki
Kappei
K
Matsumoto
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage*; D013997:Time Factors
D018686:Anesthetics, Intravenous; D015742:Propofol