[Micellar liquid chromatography and its application in toxicological analysis].
Micellar liquid chromatography (MLC) is a reversed phase liquid chromatography with mobile phases containing surfactant above its critical micellar concentration (CMC). The basic mechanism and advantages of MLC in physicochemical analysis were reviewed, and its applications in analysis of drugs, barbiturates, benzodiazepines were chiefly introduced in this paper. MLC is a potential method to toxicological analysis due to strong selectivity, wide application scope and easy biological samples, etc.
Cheng
Xiang-wei
XW
Zhejiang Police College, Hangzhou 310053, China. xweicheng@163.com
Jiang
Wen-hui
WH
Chu
Jian-xin
JX
D000701:Analgesics, Opioid / Q000032:analysis*; D001463:Barbiturates / Q000032:analysis* / Q000737:chemistry; D001569:Benzodiazepines / Q000032:analysis* / Q000737:chemistry; D002853:Chromatography, Liquid / Q000379:methods*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000032:analysis* / Q000737:chemistry; D008823:Micelles; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012997:Solvents / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry
D000701:Analgesics, Opioid; D001463:Barbiturates; D006993:Hypnotics and Sedatives; D008823:Micelles; D012997:Solvents; D013501:Surface-Active Agents; D001569:Benzodiazepines