Tandem Nazarov cyclization-halovinylation of divinyl ketones under Vilsmeier conditions: synthesis of highly substituted cyclopentadienes.
A new Vilsmeier reagent-mediated Nazarov cyclization-halovinylation reaction of divinyl ketones was developed to provide a straightforward method for the synthesis of highly substituted cyclopentadienes with the advantages of simplicity of execution, readily available substrates, cheap reagents, and broad range of potential products and applications.
Department of Chemistry, Northeast Normal University, Changchun 130024, China. wangm452@nenu.edu.cn
Mang
M
Wang
Feng
F
Han
Hongjuan
H
Yuan
Qun
Q
Liu