Inhibitory effects of Rosa gallica on the digestive enzymes.
The 50% aqueous ethanol extracts of petals of Rosa gallica collected in Xinjiang province, China, exhibited potent inhibitory effects against alpha-amylase and alpha-glucosidase. As the active principles, seven hydrolysable tannins were isolated from this species for the first time and elucidated by NMR and ESI-TOF-MS analysis. Quantitative analysis by ultra-performance liquid chromatography demonstrated that the contents of these hydrolysable tannins were 3-5% of the dry weight of the petals, and the hydrolysable tannins must be related to the medicinal utilization of this species.
Ochir
Sarangowa
S
Kitami Institute of Technology, 165 Koen-cho, Kitami 090-8507, Japan.
Nishizawa
Makoto
M
Park
Byoung Jae
BJ
Ishii
Kouta
K
Kanazawa
Tsutomu
T
Funaki
Minoru
M
Yamagishi
Takashi
T
D002681:China; D002851:Chromatography, High Pressure Liquid; D004789:Enzyme Activation / Q000187:drug effects; D047348:Hydrolyzable Tannins / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D027826:Rosa / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D000516:alpha-Amylases / Q000378:metabolism*; D000520:alpha-Glucosidases / Q000378:metabolism*
D047348:Hydrolyzable Tannins; D010936:Plant Extracts; D000516:alpha-Amylases; D000520:alpha-Glucosidases