Evaluation of endoscopy in localizing transgastric access for natural orifice transluminal endoscopic surgery in humans.
BACKGROUND
To date, transgastric access in humans for natural orifice transluminal endoscopic surgery (NOTES) has been poorly evaluated.


OBJECTIVE
To compare endoscopic visualization of the transgastric access point with the laparoscopically defined ideal entrance to the peritoneal cavity.


METHODS
Prospective pilot study in humans.


METHODS
Single tertiary-care center.


METHODS
This study involved 31 patients referred for laparoscopic cholecystectomy.


METHODS
Access points were marked by endoscopy alone, endoscopy combined with diaphanoscopy, and endoscopy after pneumoperitoneum. Points were correlated with a laparoscopically visualized, previously defined ideal access area.


METHODS
To choose the appropriate access point within the laparoscopically defined ideal access area to the peritoneal cavity away from major vessels and adjacent organs, by using endoscopy and to establish landmarks for the endoscopist, look for a learning curve, and identify potential problems.


RESULTS
The percentage of access points within the laparoscopically defined ideal area was 35.5% with endoscopy alone, 13.8% using the diaphanoscopy method, and 45.2% after transcutaneous pneumoperitoneum. A safe access point (> or = 3 cm from major gastric vessels) could be achieved with the 3 techniques in 83.9%, 65.5%, and 87.1% of patients, respectively. A positive learning curve for endoscopic localization was identified before (P = .008) and after (P = .014) pneumoperitoneum. Virtual complications were greater in obese patients.


CONCLUSIONS
This was a small pilot study with hypothetical complications and problems, because actual transgastric access was not performed. The criteria for an ideal access area were very strict.


CONCLUSIONS
Endoscopy, especially with the use of pneumoperitoneum, can reliably locate a safe transgastric entrance point. However, the endoscopically chosen site correlates poorly with the ideal laparoscopically determined site for transgastric access.
Linke
Georg R
GR
Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Zerz
Andreas
A
Kapitza
Florian
F
Warschkow
Rene
R
Lange
Jochen
J
Meyenberger
Christa M
CM
Binek
Janek
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017081:Cholecystectomy, Laparoscopic / Q000295:instrumentation* / Q000379:methods; D004724:Endoscopy; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010529:Peritoneal Cavity / Q000601:surgery*; D010865:Pilot Projects; D011446:Prospective Studies; D013270:Stomach / Q000601:surgery*; D055815:Young Adult