Investigation of energy dependence of EBT and EBT-2 gafchromic film.
OBJECTIVE
The purpose of this study was to quantify the extent of energy dependence of Gafchromic film to x-ray energies ranging in quality from 105 kVp to 6 MV, and relate this dependency to the film's chemical composition and date of production.


METHODS
Lots of Gafchromic EBT film manufactured in 2004 and 2005 together with more recent batches produced in 2007 were evaluated for energy dependence. Multiple batches of EBT-2 film were also evaluated. Energy dependence was quantified as Rx-the ratio of net optical density (netOD) measured at a given energy x relative to the netOD measured at 6 MV, as measured on a linear accelerator. Rx was evaluated for beam qualities of 105 and 220 kVp on a clinical orthovoltage unit using two separate techniques-a flatbed scanner (Epson) and a real-time fiber-optic readout system. Neutron activation analysis for chlorine and bromine content was performed on all the films to determine whether the composition of the film had changed between batches of film exhibiting different energy dependence responses.


RESULTS
For batches of EBT manufactured in 2007, R105 kVp was 0.75 and R220 kVp was 0.85, indicating an under-response at orthovoltage energies. These results were confirmed using both the Epson flatbed scanner as well as the real-time readout system. For batches of EBT film manufactured before 2006, Rl05 kVp ranged from 0.9 to 1.0. The results from the neutron activation analysis confirmed a direct relationship between the concentration of chlorine and the magnitude of under-response at orthovoltage energies. EBT-2 film exhibited R105 kVp values ranging from 0.79 (under-response) to 1.20 (over-response) among batches containing varying concentrations of bromine, chlorine, and potassium.


CONCLUSIONS
The results of this study indicated that differences in energy response of EBT and EBT-2 films were due to differences in the chemical composition and therefore the effective atomic number of the film, which have changed over time. To achieve an energy independent dosimeter over a range of kilovoltage energies, the effective atomic number of the dosimeter must be closely matched to that of water. Small deviations in chemical composition can lead to large deviations in response as a function of energy.
Department of Radiation Oncology, Radiation Physics, and Princess Margaret Hospital, University of Toronto, Toronto, Ontario M5G 2M9, Canada. patricia.lindsay@rmp.uhn.on.ca
Patricia
P
Lindsay
Alexandra
A
Rink
Mark
M
Ruschin
David
D
Jaffray
D004307:Dose-Response Relationship, Radiation; D004735:Energy Transfer; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods; D011829:Radiation Dosage; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity