Increased risk of stroke after adhesive capsulitis: a population-based study.
OBJECTIVE
No previous study has described the association between stroke and previous adhesive capsulitis (AC). This study aims to investigate the risk of stroke after AC with a population-based database.


METHODS
Records for 10 935 with a principal diagnosis of AC and 32 805 randomly selected controls were collected between 2000 and 2003. The log-rank test was performed to analyze the differences in accumulated stroke-free survival rates between the 2 groups. Cox proportional hazard regressions were performed to calculate the longitudinal hazard of stroke.


RESULTS
During the follow-up period, 575 patients from the study group (5.3%) and 1201 from the comparison group (3.7%) had strokes. The crude hazard ratio for stroke for patients with AC was 1.46-times greater than for controls (95% CI, 1.32-1.62; P<0.001), and the adjusted hazard ratio was 1.22 (95% CI, 1.06-1.40; P=0.002).


CONCLUSIONS
Our study demonstrates increased prevalence and risk of stroke after AC. Further study is needed to confirm our findings and explore underlying mechanisms.
Kang
Jiunn-Horng
JH
Department of Physical Medicine and Rehabilitation and Neuroscience Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
Sheu
Jau-Jiuan
JJ
Lin
Herng-Ching
HC
D000328:Adult; D000368:Aged; D002062:Bursitis / Q000150:complications* / Q000401:mortality*; D016208:Databases, Factual / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012307:Risk Factors; D020521:Stroke / Q000209:etiology* / Q000401:mortality*; D015996:Survival Rate / Q000639:trends