[Research progress on the efficacy, metabolism and bioavailability of mebendazole in hydatid disease].
Mebendazole is currently used in the treatment of hydatid disease. Its poor absorption from the gastrointestinal tract and low bioavailability aroused further research on new formulations of mebendazole to increase the bioavailability and improve the therapeutic efficacy. This review summarizes the recent research progress.
Liu
Cong-Shan
CS
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Zhang
Hao-Bing
HB
D000818:Animals; D000871:Anthelmintics / Q000493:pharmacokinetics / Q000627:therapeutic use; D001682:Biological Availability; D004443:Echinococcosis / Q000188:drug therapy*; D006801:Humans; D008463:Mebendazole / Q000493:pharmacokinetics* / Q000627:therapeutic use*
D000871:Anthelmintics; D008463:Mebendazole