Selection of bifidobacteria based on adhesion and anti-inflammatory capacity in vitro for amelioration of murine colitis.
Adhesion and anti-inflammatory properties of eight strains of bifidobacteria were tested using the intestinal epithelial cell lines Caco-2, T84, and HT29. Two strains were selected for further assessment of their anti-inflammatory capacity in two murine models of colitis. In vivo results confirmed the high anti-inflammatory capacity of a Bifidobacterium bifidum strain.
Institute of Microbiology and Biotechnology, University of Ulm, Ulm, Germany.
Julia
J
Preising
David
D
Philippe
Marita
M
Gleinser
Hua
H
Wei
Stephanie
S
Blum
Bernhard J
BJ
Eikmanns
Jan-Hendrik
JH
Niess
Christian U
CU
Riedel
D000818:Animals; D001422:Bacterial Adhesion; D001644:Bifidobacterium / Q000502:physiology*; D018938:Caco-2 Cells; D003092:Colitis / Q000628:therapy*; D006801:Humans; D018836:Inflammation Mediators / Q000378:metabolism; D007413:Intestinal Mucosa / Q000382:microbiology; D051379:Mice; D019936:Probiotics
D018836:Inflammation Mediators