Phytotoxic activity of quinones and resorcinolic lipid derivatives.
On the basis of the reported phytotoxic activity of sorgoleone and resorcinolic lipids identified from the root extracts of Sorghum bicolor , 8 resorcinolic lipid derivatives and 10 quinones with various side chain sizes were synthesized. The phytotoxicity of the compounds was tested against a monocot and a dicot species. The quinones were phytotoxic, whereas the resorcinolic lipids were not. Of the quinones, 2-hydroxy-5-methoxy-3-pentylcyclohexa-2,5-diene-1,4-dione, having a five-carbon side chain, showed phytotoxic activity similar to that of natural compound sorgoleone.
Mizuno
Cassia S
CS
Natural Products Utilization Research Unit, Agricultural Research Service, U.S. Department of Agriculture, University, Mississippi 38677-8048, USA.
Rimando
Agnes M
AM
Duke
Stephen O
SO
D008055:Lipids / Q000737:chemistry / Q000633:toxicity*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000633:toxicity*; D010944:Plants / Q000187:drug effects*; D011809:Quinones / Q000737:chemistry / Q000633:toxicity*; D045868:Sorghum / Q000737:chemistry*
D008055:Lipids; D010936:Plant Extracts; D011809:Quinones