Comparison of drug permeabilities and BCS classification: three lipid-component PAMPA system method versus Caco-2 monolayers.
Teksin
Zeynep S
ZS
University of Maryland School of Pharmacy, Baltimore, Maryland 21201, USA.
Seo
Paul R
PR
Polli
James E
JE
D000319:Adrenergic beta-Antagonists / Q000378:metabolism; D000818:Animals; D018938:Caco-2 Cells; D002460:Cell Line; D002463:Cell Membrane Permeability / Q000187:drug effects; D004285:Dogs; D006801:Humans; D008567:Membranes, Artificial; D008790:Metoprolol / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000145:classification* / Q000378:metabolism*; D011237:Predictive Value of Tests; D012015:Reference Standards
D000319:Adrenergic beta-Antagonists; D008567:Membranes, Artificial; D004364:Pharmaceutical Preparations; D008790:Metoprolol