Stereoselective synthesis of trisubstituted aziridines with N-alpha-diazoacyl camphorsultam.
A Brønsted acid-catalyzed reaction of alpha-substituted alpha-diazocarbonyl compounds bearing camphorsultam as a chiral auxiliary and N-alkoxycarbonyl imines was implemented as an unprecedented means to provide trisubstituted aziridines in a highly stereodefined manner.
Hashimoto
Takuya
T
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Nakatsu
Hiroki
H
Watanabe
Shogo
S
Maruoka
Keiji
K