Quantifying HIV for monitoring antiretroviral therapy in resource-poor settings.
There is increasing evidence to support the inability of CD4 cell count monitoring to predict virological failure in human immunodeficiency virus-infected individuals receiving antiretroviral therapy. There is renewed interest in improving access to viral load monitoring in resource-constrained regions to monitor adherence to treatment and to switch therapy. The field is rapidly changing as new technology platforms are made available for evaluation. This article presents an up to date summary of the assays available for viral load monitoring and suggests approaches for their implementation.
Stevens
Wendy S
WS
Department of Molecular Medicine and Haematology, University of Witwatersrand, Johannesburg, South Africa. wendy.stevens@nhls.ac.za
Scott
Lesley E
LE
Crowe
Suzanne M
SM
D003906:Developing Countries; D016903:Drug Monitoring / Q000379:methods*; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology*; D006801:Humans; D019562:Viral Load / Q000379:methods*