Reversible hypohidrosis with topiramate therapy for chronic migraine.
Topiramate is an anticonvulsant medication that is widely used for migraine prophylaxis. Hypohidrosis and hyperthermia are 2 rare adverse effects of topiramate treatment, which have mainly occurred in pediatric epilepsy patients. Herein, we describe the first case of reversible hypohidrosis in an adult patient treated with topiramate for chronic migraine.
Albert Einstein College of Medicine, Saul R Korey Department of Neurology, Montefiore Headache Center, Bronx, NY 10461, USA.
Shira Y
SY
Markowitz
Matthew S
MS
Robbins
Clair
C
Cascella
Huma U
HU
Sheikh
Brian M
BM
Grosberg
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects; D005334:Fever / Q000139:chemically induced / Q000503:physiopathology; D005440:Fluid Therapy; D005632:Fructose / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D020773:Headache Disorders / Q000188:drug therapy; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D006973:Hypertension / Q000150:complications; D007007:Hypohidrosis / Q000139:chemically induced* / Q000503:physiopathology*; D007262:Infusions, Intravenous; D008297:Male; D008881:Migraine Disorders / Q000188:drug therapy*; D009767:Obesity, Morbid / Q000150:complications; D010353:Patient Education as Topic; D012891:Sleep Apnea Syndromes / Q000150:complications; D013545:Sweat Glands / Q000187:drug effects / Q000503:physiopathology; D013546:Sweating / Q000187:drug effects / Q000502:physiology; D000077236:Topiramate; D016896:Treatment Outcome
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose