Mumps vaccine effectiveness in highly immunized populations.
The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.
Department of Public Health, University of Barcelona, Casanova 143, 08036, Barcelona, Spain. angela.dominguez@ub.edu
Angela
A
Domínguez
Núria
N
Torner
Jesús
J
Castilla
Joan
J
Batalla
Pere
P
Godoy
Marcela
M
Guevara
Dolors
D
Carnicer
Joan
J
Caylà
Cristina
C
Rius
Josep Maria
JM
Jansà
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D006801:Humans; D007223:Infant; D009107:Mumps / Q000453:epidemiology / Q000517:prevention & control*; D009108:Mumps Vaccine / Q000008:administration & dosage / Q000276:immunology*; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
D009108:Mumps Vaccine