[Field evaluation of gold-immunochromatographic assay for diagnosis of vivax malaria].
OBJECTIVE
To evaluate a gold-immunochromatographic assay (GICA) for malaria diagnosis in an endemic area of vivax malaria.


METHODS
Blood samples were collected from febrile patients in 5 township-hospitals of Mengcheng County, Anhui Province, between September and October 2008. The samples were examined by GICA and microscopy under double blind condition and the results were compared.


RESULTS
Among 292 blood samples, 181 were found P. vivax-positive by microscopy, and 163 were positive by GICA. Altogether, the coincidence of the two methods stood for 92.8% (271/292), including 108 negatives and 163 positives. 21 samples with discrepancy covered 18 microscopy positive but GICA negative, 3 microscopy negative but GICA positive. The GICA positive rate in patients with a parasitaemia of > 1,000 parasites/microl, 100-1,000 parasites/microl, and < 100 parasites/microl was 93.5% (115/123), 86.0% (43/50), and 62.5% (5/8), respectively.


CONCLUSIONS
GICA is a useful diagnosis method for endemic area of vivax malaria.
Wang
Jun-Yun
JY
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Wang
Jian-Jun
JJ
Shi
Feng
F
Xu
Xian
X
Yang
Yue-Tao
YT
Gao
Chun-Hua
CH
Zheng
Xiang
X
Ge
Jun
J
Tang
Lin-Hua
LH
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D017979:Gold Colloid; D006801:Humans; D007118:Immunoassay; D007223:Infant; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010966:Plasmodium vivax; D055815:Young Adult
D017979:Gold Colloid