Acute necrotizing encephalopathy in a child during the 2009 influenza A(H1N1) pandemia: MR imaging in diagnosis and follow-up.
The recently emerged novel influenza A(H1N1) virus continues to spread globally. The clinical disease generally appears mild, but unfavorable outcomes have been reported. We describe a case of a 3-year-old Italian girl infected with influenza A(H1N1) virus presenting with neurologic deterioration. CT findings were negative, but MR imaging findings were consistent with ANE. To our knowledge, this is the first case reported in Europe and the second in worldwide pediatric radiology literature.
Department of Diagnostic Neuroradiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy. formitti@ao.pr.it
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Ormitti
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Picetti
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D000208:Acute Disease; D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology / Q000473:pathology*; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000453:epidemiology / Q000473:pathology* / Q000821:virology*; D008279:Magnetic Resonance Imaging