Mumps vaccine effectiveness in highly immunized populations.
The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.
Domínguez
Angela
A
Department of Public Health, University of Barcelona, Casanova 143, 08036, Barcelona, Spain. angela.dominguez@ub.edu
Torner
Núria
N
Castilla
Jesús
J
Batalla
Joan
J
Godoy
Pere
P
Guevara
Marcela
M
Carnicer
Dolors
D
Caylà
Joan
J
Rius
Cristina
C
Jansà
Josep Maria
JM
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D006801:Humans; D007223:Infant; D009107:Mumps / Q000453:epidemiology / Q000517:prevention & control*; D009108:Mumps Vaccine / Q000008:administration & dosage / Q000276:immunology*; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
D009108:Mumps Vaccine