A pterocarpan from the seeds of Bituminaria morisiana.
A new prenylated pterocarpan, named morisianine, was isolated together with the known secondary metabolites erybraedin C, psoralen and angelicin from the seeds of Bituminaria morisiana. The structures of the compounds were elucidated mainly by 1D and 2D NMR experiments as well as mass spectrometry. The new compound was subjected to cytotoxicity screening against a panel of human cancer cells.
Leonti
Marco
M
Dipartimento Farmaco Chimico Tecnologico, University of Cagliari, via Ospedale 72, 09124, Cagliari, Italy.
Casu
Laura
L
Gertsch
Jürg
J
Bonsignore
Leonardo
L
Floris
Costantino
C
Casu
Mariano
M
Cottiglia
Filippo
F
D018938:Caco-2 Cells; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D007887:Fabaceae / Q000737:chemistry*; D005363:Ficusin / Q000737:chemistry; D011564:Furocoumarins / Q000737:chemistry; D018922:HL-60 Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D036343:Pterocarpans / Q000737:chemistry* / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry*
D011564:Furocoumarins; D036343:Pterocarpans; C488769:erybraedin C; C011659:angelicin; D005363:Ficusin