Cell adhesion through clustered ligand on fluid supported lipid bilayers.
The quartz crystal microbalance technique with dissipation monitoring and the complementary optical microscopy technique were used for monitoring cell adhesion on an RGD-functionalized supported lipid bilayer. A critical interligand RGD spacing of nearly 80 nm was estimated for cell adhesion when an RGD spacing of 10 nm was necessary to observe flattened cells on a fluid surface.
Sandrin
Ludivine
L
Département de Chimie Moléculaire, UMR CNRS/UJF 5250, ICMG FR 2607, 301 rue de la chimie, BP53, 38041 Grenoble cedex 9, France.
Coche-Guérente
Liliane
L
Bernstein
Amandine
A
Basit
Hajra
H
Labbé
Pierre
P
Dumy
Pascal
P
Boturyn
Didier
D
D002448:Cell Adhesion; D002460:Cell Line; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry*; D008853:Microscopy / Q000379:methods*; D009842:Oligopeptides / Q000737:chemistry*; D011791:Quartz / Q000737:chemistry; D013499:Surface Properties
D008051:Lipid Bilayers; D009842:Oligopeptides; D011791:Quartz; C047981:arginyl-glycyl-aspartic acid