From crabshell to chitosan-hydroxyapatite composite material via a biomorphic mineralization synthesis method.
Hydroxyapatite-polymer composite materials, as biological bone tissue materials, have become an important research direction. In this paper, the calcium carbonate from the crabshells was transformed into hydroxyapatite by a hydrothermal process. According to the method that we called Biomorphic Mineralization synthesis, we obtained a novel kind of hydroxyapatite-chitosan composite materials which reserved the natural perfect structure of the original crabshells. Benefited from its fine micro-structure as the crabshells, this kind of materials held a high value of tensile modulus, which is expected to be promising bone tissue engineering applications.
State Key Lab of Metal Matrix Composites, Department of Materials Science and Engineering, Shanghai Jiaotong University, 800 Dongchuan Road, 200240 Shanghai, People's Republic of China.
Haoran
H
Ge
Bingyuan
B
Zhao
Yijian
Y
Lai
Xiaobin
X
Hu
Di
D
Zhang
Keao
K
Hu
D000818:Animals; D001842:Bone and Bones; D048271:Chitosan / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D008420:Manufactured Materials / Q000032:analysis; D011108:Polymers / Q000737:chemistry; D023822:Tissue Engineering
D011108:Polymers; D048271:Chitosan; D017886:Durapatite