Multiple skin metastases to vulva from carcinoma of the cervical stump.
Metastases to the skin occur rarely in the cervical carcinoma, even in terminal stage of the disease. The frequency of metastasis is estimated from 0.01% to 2%. The presence of metastasis suggests generalized dissemination of the disease and reflects a rapidly progressive process that appear in the final stage of the disease.


METHODS
We present a case of skin metastases in patients with squamous cell carcinoma of the cervical stump after the previous supracervical hysterectomy for benign disease of the uterus. The extensive skin changes on vulva and perineum occurred after radical trachelectomy and external radiation therapy. Patient received HDR brachytherapy for recurrent lesions, but the effect of treatment was poor and she died of progressive disease.


CONCLUSIONS
As far as we know this is the first case report of squamous cell carcinoma in the cervical stump metastasizing to skin. Palliative brachytherapy has a limited role in controlling symptoms. Skin metastases indicate an aggressive and progressive process.
Grabiec
Marek
M
Department of Obstetrics and Gynecology, Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, Toruń, Poland. grabiecm@cm.umk.pl
Walentowicz
Małgorzata
M
Marszałek
Andrzej
A
D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000532:radiotherapy / Q000556:secondary*; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy; D014846:Vulvar Neoplasms / Q000473:pathology / Q000556:secondary*