Nephrotic syndrome associated with invasive mole: a case report.
Gestational trophoblastic disease describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial), placental site trophoblastic tumour, choriocarcinoma and gestational trophoblastic neoplasia (GTN). Invasive moles are responsible for most cases of localized GTN. Two cases of GTN previously reported in the literature exhibited membranous glomerulonephritis (MGN). However, histologic examinations in our case did not reveal evidence of MGN. Clinical features and pathologic findings were consistent with minimal change disease associated with an invasive mole. In the present case, we observed complete remission of nephrotic syndrome following removal of the invasive mole.
Department of Nephrology, Yonsei University Wonju College of Medicine, 162 Ilsan-dong, Wonju, Kangwon-do, South Korea.
Jae Won
JW
Yang
Seung Ok
SO
Choi
Bi Ro
BR
Kim
Young Sub
YS
Kim
Jong Myoung
JM
Yoo
Min Seob
MS
Eom
Byoung Geun
BG
Han
D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000175:diagnosis / Q000209:etiology*; D011247:Pregnancy; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery