Scalable and efficient synthesis of the mycolactone core.
A highly efficient, scalable, and stereoselective synthesis of the mycolactone core is reported. The synthesis consists of 14 longest linear steps, with 19% overall yield.
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
Katrina L
KL
Jackson
Wenju
W
Li
Chi-Li
CL
Chen
Yoshito
Y
Kishi