Comparison of in vitro fluoride uptake from whitening toothpastes and a conventional toothpaste in demineralised enamel.
Studies on the compatibility of abrasives and fluoride compounds deal exclusively with fluoride uptake and remineralization after storing the enamel specimens in a toothpaste-saliva mixture. The influence of brushing on the fluoride uptake when highly abrasive toothpastes are used has hardly been investigated so far. The aim of the present study was to investigate fluoride uptake in initially demineralised dental enamel after storage in, or brushing with, whitening toothpaste slurries, compared to a conventional toothpaste. For this purpose two widely available whitening toothpastes with ionically bound fluoride (sodium fluoride NaF), two with covalently-bound fluoride toothpastes (sodium monofluorophosphate, NaMFP) and a conventional amine fluoride toothpaste (AmF) were compared. The fluoride uptake after use of the AmF toothpaste was shown to be statistically significantly higher than that after application of the NaF toothpastes, which in turn was statistically significantly higher than the uptake resulting from NaMFP application. The fluoride uptake was slightly higher when the enamel samples were brushed with NaF toothpaste, rather than just stored in the respective toothpaste slurry. Brushing with highly abrasive toothpastes did not negatively influence fluoride uptake in demineralised dental enamel. The ionic form of the fluoride in toothpastes appears to be critical for increased fluoride uptake. The acidic components of the AmF toothpaste improved fluoride uptake compared to alkaline NaF toothpastes.
Department of Operative Dentistry and Periodontology, University Dental School, University of Freiburg, Freiburg, Germany. markus.altenburger@uniklinik-freiburg.de
Markus J
MJ
Altenburger
Jasmin
J
Bernhart
Thurid D
TD
Schicha
Karl-Thomas
KT
Wrbas
Elmar
E
Hellwig
D000818:Animals; D002327:Cariostatic Agents / Q000737:chemistry / Q000493:pharmacokinetics*; D002417:Cattle; D003743:Dental Enamel / Q000378:metabolism* / Q000473:pathology; D005459:Fluorides / Q000737:chemistry / Q000493:pharmacokinetics*; D005460:Fluorides, Topical / Q000493:pharmacokinetics; D010710:Phosphates / Q000493:pharmacokinetics; D012463:Saliva / Q000737:chemistry; D012969:Sodium Fluoride / Q000493:pharmacokinetics; D058205:Tooth Bleaching Agents / Q000493:pharmacokinetics; D017001:Tooth Demineralization / Q000378:metabolism*; D014089:Tooth Remineralization; D014099:Toothbrushing / Q000379:methods; D014100:Toothpastes / Q000737:chemistry / Q000493:pharmacokinetics*
D002327:Cariostatic Agents; D005460:Fluorides, Topical; D010710:Phosphates; D058205:Tooth Bleaching Agents; D014100:Toothpastes; C094808:amine fluoride solution; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides