Primary intracranial malignant peripheral nerve sheath tumour responding to chemotherapy.
Malignant peripheral nerve sheath tumours (MPNST) are a rare variety of soft tissue sarcomas (STS) arising from major peripheral nerve branches and typically located in the lower extremity, chest wall or the retroperitoneum. It is a biologically aggressive neoplasm for which the treatment of choice is surgery, but usually requires a multimodality approach, having been generally labelled as chemoresistant. We present a case of MPNST located intracranially with a good response to chemotherapy.
Zambrana
Francisco
F
Department of Medical Oncology, Hospital Infanta Sofía, San Sebatián de los Reyes, Madrid, Spain. currozambrana@terra.es
Vicente
Francisco
F
García-Manrique
Teresa
T
Pereira
Sofía
S
Sáinz De Zaitigui
Jesús
J
De La Cruz Merino
Luis
L
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000188:drug therapy*
D004317:Doxorubicin; D007069:Ifosfamide