THE changing seroepidemiology of varicella in Japan: 1977-1981 and 2001-2005.
We conducted an anti-varicella-zoster virus antibody seroepidemiologic survey comparing the pre- and postvaccine eras of 1977-1981 and 2001-2005. For each period, 828 samples were measured by enzyme immunoassay test and compared. The differences from 1-year-old to high-school aged children were statistically significant. The introductions of optional varicella immunization and lifestyle changes for children were considered influencing factors.
Ueno-Yamamoto
Kumi
K
Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Japan. kumi-u@nih.go.jp
Tanaka-Taya
Keiko
K
Satoh
Hiroshi
H
Araki
Kazuko
K
Kaku
Mitsuo
M
Okabe
Nobuhiko
N
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D002644:Chickenpox / Q000453:epidemiology*; D019433:Chickenpox Vaccine / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D055815:Young Adult
D000914:Antibodies, Viral; D019433:Chickenpox Vaccine