[Landiolol hydrochloride is useful for anesthetic management of cesarean section in a patient with Basedow disease].
We report successful anesthetic management of elective cesarean section in a 30-year-old patient with Basedow disease using landiolol hydrochloride, a short-acting beta-1 adrenergic blocker of which greatest advantages are its short duration of action, rapid clearance and high beta-1 selectivity. The patient received landiolol for the prevention of aggravated tachycardia and tachyarrhythmia during cesarean section. She received landiolol continuous infusion at a rate of 5 microg x kg x min(-1) to 8 microg x kg x min(-1) until the uneventful delivery of the infant with good Apgar score, under combined spinal epidural anesthesia (CESA). We could maintain maternal hemodynamics stable leading to good post-cesarean uterus contraction. No severe adverse effects were observed in the infant. In conculusion, landiolol is useful for maintaining the hemodynamics stable in a pregnant woman with Basedow disease and keeping the infant safe from any adverse effect by infusion of landiolol.
Department of Anesthesiology, Chitose City Hospital, Chitose 066-8550.
Masanobu
M
Namiki
Norihiko
N
Tsumura
Toshihiro
T
Tsukakubo
Akiyoshi
A
Namiki
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D000328:Adult; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D002585:Cesarean Section; D017558:Elective Surgical Procedures; D005260:Female; D006111:Graves Disease; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control*; D009025:Morpholines / Q000008:administration & dosage*; D019990:Perioperative Care; D011247:Pregnancy; D011248:Pregnancy Complications; D013610:Tachycardia / Q000517:prevention & control*; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives*
D000319:Adrenergic beta-Antagonists; D009025:Morpholines; C077049:landiolol; D014508:Urea