trans Regulation: do mRNAs have a herd mentality?
Control of mRNA translation and localization plays an important role in many developmental contexts. In this issue of Developmental Cell, Reveal et al. show through analysis of the oskar mRNA in Drosophila embryos that regulatory elements within mRNAs can act in trans to influence the behavior of other mRNA molecules.
Wilusz
Carol J
CJ
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Wilusz
Jeffrey
J
D000818:Animals; D004330:Drosophila / Q000196:embryology / Q000235:genetics / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D053263:Gene Regulatory Networks; D008954:Models, Biological; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism*; D050436:Regulatory Elements, Transcriptional
D029721:Drosophila Proteins; D012333:RNA, Messenger; C091675:osk protein, Drosophila