Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.
The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1-3). The structures of these compounds were determined to be (19R, 23R)-5beta, 19-epoxy-19-methoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (1), (23R)-5beta, 19-epoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (2), and (19R)-5beta, 19-epoxy-19,25-dihydroxycucurbita-6,23(E)-diene-3beta-ol 3-O-beta-D-glucopyranoside (3), by chemical and spectroscopic methods.
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Xuan Nhiem
XN
Nguyen
Van Kiem
VK
Phan
Van Minh
VM
Chau
Khac Ban
KB
Ninh
Xuan Cuong
XC
Nguyen
Minh Ha
MH
Le
Huu Tai
HT
Bui
Hong Quang
HQ
Tran
Huu Tung
HT
Nguyen
Young Ho
YH
Kim
D002236:Carbohydrate Conformation; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D029777:Momordica charantia / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane