[Gene therapy applications in gynecologic malignances management].
Gene therapy is an innovative way of treating genetic disorders, which enables removal or repair of genetic defects. Strategies of gene therapy offer new perspectives in treating cancer diseases. Numerous methods for specifically removing tumor cells are currently used. They can be divided into five main strategies: compensation of mutation effect using repression of mutated gene expression, antiangiogenic therapy and suicidal genes to eliminate tumor cells or genetic immunotherapy In the following work actual research status on gene therapy of gynecologic malignances has been presented.
Gromadzka
Agnieszka
A
Katedra i Zakład Biologii Komórki, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, ul. Rokietnicka 5D, 60-806 Poznań.
Kubiczak
Marta
M
Jankowska
Anna
A
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D018390:Gene Targeting / Q000379:methods; D015316:Genetic Therapy / Q000379:methods*; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy / Q000379:methods
D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents
Terapia genowa i jej zastosowanie w leczeniu nowotworów ginekologicznych.