[Near-drowning and cerebral infections caused by fungi belonging to the Pseudallescheria / Scedosporium-complex].
Brain infections caused by fungi of the Pseudallescheria / Scedosporium-complex weeks or months after a near drowning event should be considered, since mortality rate is high and specific diagnostic methods are necessary for fungal detection. Voriconazole is the only authorised antimycotic drug available for the treatment of these infections in Germany, but other antimycotics may also be indicated for alternate or combined treatment strategies. Consultation of a specific reference laboratory is recommended in comparable relevant cases.
Horré
Regine
R
Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie des Universitätsklinikums Bonn. regine.horre@gmx.de
Lackner
Michaela
M
Buzina
Walter
W
Tintelnot
Kathrin
K
D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001921:Brain / Q000382:microbiology; D002494:Central Nervous System Infections / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D002675:Child, Preschool; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D015701:Near Drowning / Q000150:complications* / Q000382:microbiology; D011541:Pseudallescheria; D011743:Pyrimidines / Q000627:therapeutic use*; D021681:Scedosporium; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole; D055815:Young Adult
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole
Scedosporiosen nach Beinahe-Ertrinkungsunfällen - Gehirninfektionen durch Pilze des Pseudallescheria / Scedosporium-Komplexes.