Targeted contrast agents--an adjunct to whole-body imaging: current concepts.
This article reviews the potential use of a combination of whole-body imaging and targeted contrast agents in improving diagnostics, with a particular focus on oncology imaging. It looks at the rationale for nanoparticles and their development as targeted contrast agents. It subsequently describes many of the advances made thus far in developing tissue-specific contrast agents capable of targeting tumors that combined with whole-body imaging may enable superior cancer detection and characterization.
Foran
Paul
P
Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland. paulforan2006@gmail.com
Bolster
Ferdia
F
Crosbie
Ian
I
MacMahon
Peter
P
O'Kennedy
Richard
R
Eustace
Stephen J
SJ
D003287:Contrast Media; D006801:Humans; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles; D009369:Neoplasms / Q000175:diagnosis; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D003287:Contrast Media