A pterocarpan from the seeds of Bituminaria morisiana.
A new prenylated pterocarpan, named morisianine, was isolated together with the known secondary metabolites erybraedin C, psoralen and angelicin from the seeds of Bituminaria morisiana. The structures of the compounds were elucidated mainly by 1D and 2D NMR experiments as well as mass spectrometry. The new compound was subjected to cytotoxicity screening against a panel of human cancer cells.
Dipartimento Farmaco Chimico Tecnologico, University of Cagliari, via Ospedale 72, 09124, Cagliari, Italy.
Marco
M
Leonti
Laura
L
Casu
Jürg
J
Gertsch
Leonardo
L
Bonsignore
Costantino
C
Floris
Mariano
M
Casu
Filippo
F
Cottiglia
D018938:Caco-2 Cells; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D007887:Fabaceae / Q000737:chemistry*; D005363:Ficusin / Q000737:chemistry; D011564:Furocoumarins / Q000737:chemistry; D018922:HL-60 Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D036343:Pterocarpans / Q000737:chemistry* / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry*
D011564:Furocoumarins; D036343:Pterocarpans; C488769:erybraedin C; C011659:angelicin; D005363:Ficusin