Sensitive detection of acrolein in serum using time-resolved luminescence.
A novel lanthanide probe was designed, synthesized, and employed for a sensitive and reliable assay of acrolein based on time-resolved luminescence measurement, which suppresses the background signal of serum.
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Masataka
M
Togashi
Yasuteru
Y
Urano
Hirotatsu
H
Kojima
Takuya
T
Terai
Kenjiro
K
Hanaoka
Kazuei
K
Igarashi
Yasunobu
Y
Hirata
Tetsuo
T
Nagano
D000171:Acrolein / Q000097:blood*; D001774:Blood Chemical Analysis / Q000379:methods*; D057166:High-Throughput Screening Assays; D006801:Humans; D028581:Lanthanoid Series Elements / Q000138:chemical synthesis / Q000737:chemistry; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry; D008163:Luminescent Measurements; D015203:Reproducibility of Results; D013997:Time Factors
D028581:Lanthanoid Series Elements; D049408:Luminescent Agents; D000171:Acrolein