Doxycycline regulated lentiviral vectors.
Lentiviral vectors are a powerful tool to achieve regulated expression of transgenes in vivo and in vitro. The doxycycline-inducible system is well characterized and can be used to regulate expression mediated by lentiviral vectors. Because many different doxycycline-inducible lentiviral vectors have been described, choosing the best vector system can be difficult. This chapter can be used as a guide to select the optimal system for a particular application.
AMC Liver Center, Amsterdam, The Netherlands.
David
D
Markusic
Jurgen
J
Seppen
D004318:Doxycycline / Q000494:pharmacology*; D005786:Gene Expression Regulation / Q000187:drug effects*; D005822:Genetic Vectors; D016086:Lentivirus / Q000235:genetics*; D034622:RNA Interference; D019076:Transgenes
D004318:Doxycycline