Stereoselective synthesis of trisubstituted aziridines with N-alpha-diazoacyl camphorsultam.
A Brønsted acid-catalyzed reaction of alpha-substituted alpha-diazocarbonyl compounds bearing camphorsultam as a chiral auxiliary and N-alkoxycarbonyl imines was implemented as an unprecedented means to provide trisubstituted aziridines in a highly stereodefined manner.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Takuya
T
Hashimoto
Hiroki
H
Nakatsu
Shogo
S
Watanabe
Keiji
K
Maruoka