Targeted contrast agents--an adjunct to whole-body imaging: current concepts.
This article reviews the potential use of a combination of whole-body imaging and targeted contrast agents in improving diagnostics, with a particular focus on oncology imaging. It looks at the rationale for nanoparticles and their development as targeted contrast agents. It subsequently describes many of the advances made thus far in developing tissue-specific contrast agents capable of targeting tumors that combined with whole-body imaging may enable superior cancer detection and characterization.
Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland. paulforan2006@gmail.com
Paul
P
Foran
Ferdia
F
Bolster
Ian
I
Crosbie
Peter
P
MacMahon
Richard
R
O'Kennedy
Stephen J
SJ
Eustace
D003287:Contrast Media; D006801:Humans; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles; D009369:Neoplasms / Q000175:diagnosis; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D003287:Contrast Media