THE changing seroepidemiology of varicella in Japan: 1977-1981 and 2001-2005.
We conducted an anti-varicella-zoster virus antibody seroepidemiologic survey comparing the pre- and postvaccine eras of 1977-1981 and 2001-2005. For each period, 828 samples were measured by enzyme immunoassay test and compared. The differences from 1-year-old to high-school aged children were statistically significant. The introductions of optional varicella immunization and lifestyle changes for children were considered influencing factors.
Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Japan. kumi-u@nih.go.jp
Kumi
K
Ueno-Yamamoto
Keiko
K
Tanaka-Taya
Hiroshi
H
Satoh
Kazuko
K
Araki
Mitsuo
M
Kaku
Nobuhiko
N
Okabe
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D002644:Chickenpox / Q000453:epidemiology*; D019433:Chickenpox Vaccine / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D055815:Young Adult
D000914:Antibodies, Viral; D019433:Chickenpox Vaccine