From crabshell to chitosan-hydroxyapatite composite material via a biomorphic mineralization synthesis method.
Hydroxyapatite-polymer composite materials, as biological bone tissue materials, have become an important research direction. In this paper, the calcium carbonate from the crabshells was transformed into hydroxyapatite by a hydrothermal process. According to the method that we called Biomorphic Mineralization synthesis, we obtained a novel kind of hydroxyapatite-chitosan composite materials which reserved the natural perfect structure of the original crabshells. Benefited from its fine micro-structure as the crabshells, this kind of materials held a high value of tensile modulus, which is expected to be promising bone tissue engineering applications.
Ge
Haoran
H
State Key Lab of Metal Matrix Composites, Department of Materials Science and Engineering, Shanghai Jiaotong University, 800 Dongchuan Road, 200240 Shanghai, People's Republic of China.
Zhao
Bingyuan
B
Lai
Yijian
Y
Hu
Xiaobin
X
Zhang
Di
D
Hu
Keao
K
D000818:Animals; D001842:Bone and Bones; D048271:Chitosan / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D008420:Manufactured Materials / Q000032:analysis; D011108:Polymers / Q000737:chemistry; D023822:Tissue Engineering
D011108:Polymers; D048271:Chitosan; D017886:Durapatite