Proteins involved in Campylobacter jejuni 81-176 recovery after high-pressure treatment.
Campylobacteriosis has been recognized as the major bacterial food-borne infection worldwide. Campylobacter, especially C. jejuni, contaminate mainly poultry meat. Although more sensitive than other food-borne pathogens to many stresses, C. jejuni can survive food processing and go on to reach its final reservoir (the human gut). Genomic analyses of this organism indicate a lack of genes described in other gram-negative bacteria to overcome stresses. The high-pressure recovery response of C. jejuni 81-176 was analyzed from two-dimensional electrophoretic profiles of the cytoplasmic proteome. The main cellular mechanisms controlling the down- and upregulated proteins are discussed.
UMR-INRA SECALIM ENVN/ENITIAA, Ecole Nationale Vétérinaire de Nantes, France.
Clémence
C
Bièche
Marie
M
de Lamballerie
Michel
M
Federighi
Alain
A
Le Bail
Odile
O
Tresse
D001426:Bacterial Proteins / Q000378:metabolism*; D002169:Campylobacter Infections / Q000517:prevention & control; D016123:Campylobacter jejuni / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D015180:Electrophoresis, Gel, Two-Dimensional; D005511:Food Handling / Q000379:methods*; D005516:Food Microbiology; D005517:Foodborne Diseases / Q000517:prevention & control; D006801:Humans; D006874:Hydrostatic Pressure; D053858:Metabolic Networks and Pathways; D020543:Proteome / Q000302:isolation & purification / Q000378:metabolism; D013312:Stress, Physiological
D001426:Bacterial Proteins; D020543:Proteome