Analyses of bifidobacterial prophage-like sequences.
The genomes of 22 putative prophages (bifidoprophages), previously identified in bifidobacterial genomes, were analyzed to detect the presence and organization of functional modules. Bifidoprophages were shown to display a classical modular genomic organization in which the DNA lysogeny module and the DNA packaging regions are the most highly conserved. Furthermore, single phage gene as well as multiple phage gene-based phylogenetic analyses clearly revealed the chimeric make-up of the genomes of bifidoprophages.
Ventura
Marco
M
Department of Genetics, Biology of Microorganisms, Anthropology and Evolution, University of Parma, Parco Area delle Scienze 11a, 43100 Parma, Italy. marco.ventura@unipr.it
Turroni
Francesca
F
Foroni
Elena
E
Duranti
Sabrina
S
Giubellini
Vanessa
V
Bottacini
Francesca
F
van Sinderen
Douwe
D
D001644:Bifidobacterium / Q000821:virology*; D016000:Cluster Analysis; D042003:DNA Packaging; D004279:DNA, Viral / Q000235:genetics*; D023061:Gene Order; D005814:Genes, Viral; D008242:Lysogeny; D010802:Phylogeny; D039002:Prophages / Q000235:genetics*; D011995:Recombination, Genetic
D004279:DNA, Viral