The tango of histone marks and chaperones at replication fork.
Nucleosomes are disassembled during DNA replication. How histone modifications and histone chaperones collaborate to reassemble nucleosomes on replicated DNA is explored by Jasencakova et al. (2010) and Burgess et al. (2010) in this and a recent issue of Molecular Cell, respectively.
Falbo
Karina B
KB
Department of Carcinogenesis, Science Park Research Division, MD Anderson Cancer Center, Smithville, TX 78957, USA.
Shen
Xuetong
X
D000107:Acetylation; D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism; D042002:Chromatin Assembly and Disassembly; D004261:DNA Replication; D004271:DNA, Fungal / Q000096:biosynthesis; D004277:DNA, Single-Stranded / Q000096:biosynthesis; D051548:Histone Acetyltransferases / Q000378:metabolism; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008745:Methylation; D018832:Molecular Chaperones / Q000235:genetics / Q000378:metabolism*; D009707:Nucleosomes / Q000378:metabolism; D011485:Protein Binding; D011499:Protein Processing, Post-Translational; D016196:S Phase; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D013312:Stress, Physiological / Q000235:genetics; D013997:Time Factors; D000099224:p300-CBP-Associated Factor
D018797:Cell Cycle Proteins; D004271:DNA, Fungal; D004277:DNA, Single-Stranded; D051548:Histone Acetyltransferases; D006657:Histones; D018832:Molecular Chaperones; D009707:Nucleosomes; D029701:Saccharomyces cerevisiae Proteins; C491641:ASF1A protein, human; C491640:ASF1B protein, human; C501392:GCN5 protein, S cerevisiae; D000099224:p300-CBP-Associated Factor