Progressive multifocal leukoencephalopathy in a patient with idiopathic CD4+T lymphocytopenia.
Progressive multifocal leukoencephalopathy (PML) is demyelinating of central nervous system caused by JC virus infection and often occurs in immunodeficient individuals. We report progressive PML in a 30-year-old male with idiopathic severely depressed CD4+T lymphocyte count. He was sero-negative for human immunodeficiency virus (HIV) infection.
Puri
Vinod
V
Department of Neurology, G. B. Pant Hospital, New Delhi - 110 002, India. vpuri01@gmail.com
Chaudhry
Neera
N
Gulati
Parveen
P
Patel
Nisheeth
N
Tatke
Medha
M
Sinha
Sanjiv
S
D000328:Adult; D001253:Astrocytes / Q000473:pathology; D015496:CD4-Positive T-Lymphocytes / Q000473:pathology*; D015658:HIV Infections / Q000276:immunology; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000821:virology; D008231:Lymphopenia / Q000209:etiology* / Q000473:pathology* / Q000821:virology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009836:Oligodendroglia / Q000473:pathology