[Expression of c-jun protein after experimental rat brain concussion].
OBJECTIVE
To observe e-jun protein expression after rat brain concussion and explore the forensic pathologic markers following brain concussion.


METHODS
Fifty-five rats were randomly divided into brain concussion group and control group. The expression of c-jun protein was observed by immunohistochemistry.


RESULTS
There were weak positive expression of c-jun protein in control group. In brain concussion group, however, some neutrons showed positive expression of c-jun protein at 15 min after brain concussion, and reach to the peak at 3 h after brain concussion.


CONCLUSIONS
The research results suggest that detection of c-jun protein could be a marker to determine brain concussion and estimate injury time after brain concussion.
Department of Forensic Medicine, Wannan Medical College, Wuhu 241001, China. wangmaster76@163.com
Feng
F
Wang
Yong-hong
YH
Li
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D001924:Brain Concussion / Q000378:metabolism / Q000473:pathology*; D001933:Brain Stem / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D004195:Disease Models, Animal; D005260:Female; D049429:Forensic Pathology; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism*; D016755:Proto-Oncogene Proteins c-jun / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
D016755:Proto-Oncogene Proteins c-jun