A practical Delta 1-dehydrogenation of Delta 4-3-keto-steroids with DDQ in the presence of TBDMSCl at room temperature.
A mild and efficient Delta(1)-dehydrogenation of Delta(4)-3-keto-steroids with DDQ in the presence of tertbutyldimethylchlorosilane at room temperature was developed.
College of Chemistry and Chemical Engineering, Hunan Normal University, Yuelushan, Changsha 410081, China.
Kaixiong
K
Chen
Chang
C
Liu
Le
L
Deng
Guangyu
G
Xu
D016227:Benzoquinones / Q000737:chemistry*; D002384:Catalysis; D004146:Dioxanes / Q000737:chemistry; D006865:Hydrogenation; D008956:Models, Chemical; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry*; D013696:Temperature
D016227:Benzoquinones; D004146:Dioxanes; D017646:Organosilicon Compounds; D013256:Steroids; C000928:dichlorodicyanobenzoquinone; C404749:tert-butyldimethylsilyl chloride; C025223:1,4-dioxane