Aminocarnitine ureidic derivatives as inhibitors of carnitine palmitoyltransferase I.
Tassoni
Emanuela
E
Chemistry & Analytical Department, Sigma-Tau S.p.A., Pomezia, Italy. emanuela.tassoni@sigma-tau.it <emanuela.tassoni@sigma-tau.it>
Conti
Roberto
R
Gallo
Grazia
G
Vincenti
Silvia
S
Dell'Uomo
Natalina
N
Mastrofrancesco
Lucilla
L
Ricciolini
Rita
R
Cabri
Walter
W
Carminati
Paolo
P
Giannessi
Fabio
F
D000818:Animals; D001622:Betaine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D001665:Binding Sites; D002331:Carnitine / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D002334:Carnitine O-Palmitoyltransferase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D003198:Computer Simulation; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D007004:Hypoglycemic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D051379:Mice; D051381:Rats
D004791:Enzyme Inhibitors; D007004:Hypoglycemic Agents; D001622:Betaine; C045761:emeriamine; D002334:Carnitine O-Palmitoyltransferase; D002331:Carnitine