Photoreversible DNA end capping for the formation of hairpin structures.
We describe a photoreversible DNA end capping via 3-cyanovinylcarbazole nucleoside. Doubly end-capped oligodeoxynucleotide (ODN) exhibits increased stability against snake venom phosphodiesterase and shows high thermal stability.
Yoshimura
Yoshinaga
Y
School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.
Okada
Hajime
H
Fujimoto
Kenzo
K
D003432:Cross-Linking Reagents / Q000737:chemistry* / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry* / Q000378:metabolism; D043264:Phosphodiesterase I / Q000378:metabolism; D010777:Photochemistry; D012910:Snake Venoms / Q000378:metabolism; D013696:Temperature
D003432:Cross-Linking Reagents; D009838:Oligodeoxyribonucleotides; D012910:Snake Venoms; D004247:DNA; D043264:Phosphodiesterase I; C470790:phosphodiesterase I, snake venom