Primary diffuse large B-cell central nervous system lymphoma presenting as an acute space-occupying subdural mass.
Primary dural lymphomas are very rare tumors--usually low-grade B-cell lymphomas of mucosa-associated lymphoid tissue type or marginal zone B-cell lymphomas. Primary dural involvement by diffuse large B-cell lymphoma is extremely rare, with only a few cases reported in the literature. The authors present an unusual case of primary dural involvement by a high-grade diffuse large B-cell lymphoma that presented as an acute subdural space-occupying mass and required emergency neurosurgical intervention.
Department of Neurosurgery, Salford Royal NHS Foundation Trust, Salford, UK. Raphael.Sacho@postgrad.manchester.ac.uk
Raphael H
RH
Sacho
Marco
M
Kogels
Daniel
D
du Plessis
Simon
S
Jowitt
Vivek A
VA
Josan
D000208:Acute Disease; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D001706:Biopsy; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D012086:Reoperation; D013355:Subdural Space / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate