Physical activity during pregnancy is associated with reduced fasting insulin--the Pilot Pregnancy and Active Living Study.
OBJECTIVE
To examine the relationship between physical activity during pregnancy and fasting plasma insulin measured in the second trimester.


METHODS
We conducted a pilot prospective cohort study of 69 overweight or obese women who were enrolled before 20 weeks of gestation at an obstetric clinic in Columbia, South Carolina in 2006-2007. At 24-28 weeks of gestation, fasting blood samples were collected and physical activity from the 3 months prior to the visit was assessed using a validated Pregnancy Physical Activity Questionnaire.


RESULTS
Total energy expenditure (EE) in this population was attributable to sedentary activities (24.4%) and to physical activities of different intensities (light: 44.8%, moderate: 30.2%, and vigorous: 0.6%). By type, total EE mainly came from household/caregiving activities (58.9%) with a small proportion from exercise (3.8%). After adjusting for confounders, the mean fasting insulin values across the quartiles of total EE (least to most) were 17.3, 13.0, 12.1, and 9.6 uIU/ml (P for trend=0.01).


CONCLUSIONS
Our findings suggest that increased total physical activity is associated with reduced fasting insulin levels in overweight or obese pregnant women.
Liu
Ji-Hong
JH
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA. jihong.liu2003@post.harvard.edu
Mayer-Davis
Elizabeth J
EJ
Pate
Russell R
RR
Gallagher
Alexa E
AE
Bacon
Janice L
JL
D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D009765:Obesity / Q000097:blood*; D010865:Pilot Projects; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D055815:Young Adult
D007328:Insulin