Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child.
We report the first strain of 2009 pandemic influenza A (H1N1) virus with V27A mutation in addition to S31N substitution in M2 gen. It was isolated from adamantane non-treated child.
Antón
Andrés
A
Laboratori de Microbiologia, Hospital Clínic, 08036, Barcelona, Spain. aanton76@gmail.com
Marcos
María Angeles
MA
Martínez
Miguel Julián
MJ
Ramón
Susana
S
Isanta
Ricard
R
de Molina
Patricia
P
de Anta
María Teresa Jiménez
MT
Pumarola
Tomàs
T
D000218:Adamantane / Q000627:therapeutic use*; D000293:Adolescent; D019943:Amino Acid Substitution / Q000235:genetics*; D000998:Antiviral Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics* / Q000302:isolation & purification; D007251:Influenza, Human / Q000821:virology*; D020125:Mutation, Missense; D013030:Spain; D014763:Viral Matrix Proteins / Q000235:genetics; D000086082:Viroporin Proteins
D000218:Adamantane; D000998:Antiviral Agents; D014763:Viral Matrix Proteins; C488937:M2 protein, Influenza A virus; D000086082:Viroporin Proteins