Increased risk of stroke after adhesive capsulitis: a population-based study.
OBJECTIVE
No previous study has described the association between stroke and previous adhesive capsulitis (AC). This study aims to investigate the risk of stroke after AC with a population-based database.


METHODS
Records for 10 935 with a principal diagnosis of AC and 32 805 randomly selected controls were collected between 2000 and 2003. The log-rank test was performed to analyze the differences in accumulated stroke-free survival rates between the 2 groups. Cox proportional hazard regressions were performed to calculate the longitudinal hazard of stroke.


RESULTS
During the follow-up period, 575 patients from the study group (5.3%) and 1201 from the comparison group (3.7%) had strokes. The crude hazard ratio for stroke for patients with AC was 1.46-times greater than for controls (95% CI, 1.32-1.62; P<0.001), and the adjusted hazard ratio was 1.22 (95% CI, 1.06-1.40; P=0.002).


CONCLUSIONS
Our study demonstrates increased prevalence and risk of stroke after AC. Further study is needed to confirm our findings and explore underlying mechanisms.
Department of Physical Medicine and Rehabilitation and Neuroscience Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
Jiunn-Horng
JH
Kang
Jau-Jiuan
JJ
Sheu
Herng-Ching
HC
Lin
D000328:Adult; D000368:Aged; D002062:Bursitis / Q000150:complications* / Q000401:mortality*; D016208:Databases, Factual / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012307:Risk Factors; D020521:Stroke / Q000209:etiology* / Q000401:mortality*; D015996:Survival Rate / Q000639:trends