Poroelastic behaviour of cortical bone under harmonic axial loading: a finite element study at the osteonal scale.
Bone fluid flow and its induced effects on the bone cells are important players in triggering and signalling bone formation and bone remodelling. This study aims to numerically investigate the behaviour of interstitial fluid flows in cortical bone under axial cyclic harmonic loads that mimics in vivo bone behaviour during daily activities like walking. Here, bone tissue is modelled as a fluid-saturated anisotropic poroelastic medium which consists of a periodic group of osteons. By using a frequency-domain finite element analysis, the fluid velocity field is quantified for various loading conditions and bone matrix parameters.
Nguyen
Vu-Hieu
VH
Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, UMR 8208 CNRS, 94010 Créteil cedex, France.
Lemaire
Thibault
T
Naili
Salah
S
D001826:Body Fluids / Q000378:metabolism; D016723:Bone Remodeling / Q000502:physiology; D001842:Bone and Bones / Q000166:cytology / Q000502:physiology*; D004548:Elasticity; D045604:Extracellular Fluid / Q000502:physiology; D020342:Finite Element Analysis; D006253:Haversian System / Q000502:physiology; D008954:Models, Biological; D009043:Motor Activity / Q000502:physiology*; D016062:Porosity; D013314:Stress, Mechanical; D016138:Walking / Q000502:physiology; D016474:Weight-Bearing