Multivitamin and mineral supplementation modulates oxidative stress and antioxidant vitamin levels in serum and follicular fluid of women undergoing in vitro fertilization.
We investigated effects of multivitamin and mineral supplementation on lipid peroxidation, reduced glutathione, glutathione peroxidase, vitamin A, vitamin C and vitamin E values in serum and follicular fluid of 56 women undergoing IVF and 13 age matched control. We concluded that multivitamin and mineral supplementation in serum and follicular fluid of women undergoing IVF may strengthen the antioxidant defense system by decreasing oxidative stress.
Department of Obstetrics and Gynecology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.
M Okan
MO
Ozkaya
Mustafa
M
Nazıroğlu
D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D003131:Combined Modality Therapy; D019587:Dietary Supplements; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D015571:Follicular Fluid / Q000737:chemistry / Q000378:metabolism*; D005978:Glutathione / Q000097:blood / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000097:blood / Q000378:metabolism; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000378:metabolism / Q000628:therapy; D008903:Minerals / Q000008:administration & dosage / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects*; D010919:Placebos; D013482:Superoxide Dismutase / Q000378:metabolism; D016896:Treatment Outcome; D014815:Vitamins / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism / Q000494:pharmacology*
D000975:Antioxidants; D008903:Minerals; D010919:Placebos; D014815:Vitamins; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005978:Glutathione