[Guidelines for treating and managing pediatric HIV/AIDS in Japan].
Infant to post-pubertal adolescent pediatric HIV/AIDS cases in Japan nowadays are almost exclusively originated via mother-to-child transmission of HIV-1(MTCT). According to the National Cooperative Study Group on HIV Infected Pregnant Women and MTCT in Japan, most recent MTCT rate in Japan is 0.45 %, so the cumulative number of MTCT cases is only 46. In this paper the guidelines to control pediatric HIV/AIDS are introduced to Japanese doctors who are unfamiliar to this disease and just considering or starting initial antiretrovirals (ARV). ARV for children should be palatable, unrelated to foods, CNS-penetrating and should have least short and long acting side effects. Optimal adherence to treatment is best kept through the awareness of its importance by the patients and their guardians.
Togawa
Masao
M
Department of Pediatric Emergency Medicine, Children's Medical Center, Osaka City General Hospital.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy