Hormonal responses to resistance exercise after ingestion of carnosine and anserine.
Intramuscular carnosine buffers protons (H+) in skeletal muscle. We examined the effects of supplementation with chicken breast meat extract (CBEX) containing carnosine and anserine on hormonal responses to resistance exercise. Twenty-two men were assigned to a CBEX drink group (CBEX containing total 2 g of carnosine and anserine) (n = 14) or a placebo drink group (n = 8). The subjects ingested the prescribed drink (100 mL) twice daily for 30 days without physical training. Before and after the supplementation period, the subjects completed 5 sets of bilateral knee extension exercises (with a 90-s rest between sets). The magnitude of the increase in exercise-induced free testosterone did not change significantly after supplementation in either group. The blood lactate response to exercise was attenuated after supplementation in both groups (p < 0.05). In the CBEX group, the plasma epinephrine and norepinephrine concentrations after exercise were significantly lower after supplementation (p < 0.05). The serum growth hormone response to exercise was also reduced in the CBEX group after supplementation (delta value: 5.4 ± 1.9 ng/mL [pre] vs. 1.6 ± 0.5 ng/mL [post], p = 0.05). No significant differences in exercise-induced strength reduction (fatigue index) were observed in the 2 groups after supplementation. These results suggest that short-term supplementation with CBEX attenuates the exercise-induced epinephrine, norepinephrine, and growth hormone responses.
Goto
Kazushige
K
Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan. kgoto@aoni.waseda.jp
Maemura
Hirohiko
H
Takamatsu
Kaoru
K
Ishii
Naokata
N
D000284:Administration, Oral; D000328:Adult; D000704:Analysis of Variance; D000861:Anserine / Q000008:administration & dosage*; D002336:Carnosine / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004837:Epinephrine / Q000378:metabolism; D019382:Human Growth Hormone / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D053580:Muscle Strength / Q000187:drug effects*; D018482:Muscle, Skeletal / Q000187:drug effects*; D009638:Norepinephrine / Q000378:metabolism; D010807:Physical Endurance / Q000187:drug effects; D012016:Reference Values; D055070:Resistance Training; D013739:Testosterone / Q000097:blood*
D007773:Lactates; D019382:Human Growth Hormone; D013739:Testosterone; D002336:Carnosine; D000861:Anserine; D009638:Norepinephrine; D004837:Epinephrine