Studies in zebrafish reveal unusual cellular expression patterns of gonadotropin receptor messenger ribonucleic acids in the testis and unexpected functional differentiation of the gonadotropins.
García-López
Angel
A
Department of Biology, Division of Endocrinology and Metabolism, Utrecht University, Faculty of Science, Utrecht, The Netherlands.
de Jonge
Hugo
H
Nóbrega
Rafael H
RH
de Waal
Paul P
PP
van Dijk
Wytske
W
Hemrika
Wieger
W
Taranger
Geir L
GL
Bogerd
Jan
J
Schulz
Rüdiger W
RW
D000728:Androgens / Q000097:blood / Q000378:metabolism; D000818:Animals; D030801:Animals, Genetically Modified; D017868:Cyclic AMP-Dependent Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D020869:Gene Expression Profiling; D006062:Gonadotropins / Q000235:genetics / Q000494:pharmacology; D017403:In Situ Hybridization; D007546:Isoquinolines / Q000494:pharmacology; D007985:Leydig Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D008297:Male; D047428:Protein Kinase Inhibitors / Q000494:pharmacology; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011962:Receptors, FSH / Q000235:genetics; D011967:Receptors, Gonadotropin / Q000235:genetics*; D011974:Receptors, LH / Q000235:genetics; D011994:Recombinant Proteins / Q000494:pharmacology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012708:Sertoli Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D013449:Sulfonamides / Q000494:pharmacology; D013737:Testis / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D015027:Zebrafish / Q000235:genetics*; D029961:Zebrafish Proteins / Q000235:genetics*
D000728:Androgens; D006062:Gonadotropins; D007546:Isoquinolines; D047428:Protein Kinase Inhibitors; D012333:RNA, Messenger; D011962:Receptors, FSH; D011967:Receptors, Gonadotropin; D011974:Receptors, LH; D011994:Recombinant Proteins; D013449:Sulfonamides; D029961:Zebrafish Proteins; D017868:Cyclic AMP-Dependent Protein Kinases; C063509:N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide