Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
Ota
Asuka
A
Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Zhang
Jun
J
Ping
Peipei
P
Han
Jiahuai
J
Wang
Yibin
Y
D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism; D000818:Animals; D017209:Apoptosis; D016227:Benzoquinones / Q000494:pharmacology; D019556:COS Cells; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D002470:Cell Survival; D018833:Chaperonins / Q000235:genetics / Q000378:metabolism*; D002522:Chlorocebus aethiops; D004789:Enzyme Activation; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D047029:Lactams, Macrocyclic / Q000494:pharmacology; D048371:MAP Kinase Kinase 3 / Q000378:metabolism; D051379:Mice; D008822:Mice, Transgenic; D048308:Mitogen-Activated Protein Kinase 14 / Q000235:genetics / Q000378:metabolism*; D018832:Molecular Chaperones / Q000235:genetics / Q000378:metabolism*; D046912:Multiprotein Complexes; D009154:Mutation; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000201:enzymology*; D018384:Oxidative Stress; D010766:Phosphorylation; D011485:Protein Binding; D034622:RNA Interference; D051381:Rats; D011994:Recombinant Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics; D013997:Time Factors; D014162:Transfection
D048868:Adaptor Proteins, Signal Transducing; D016227:Benzoquinones; C498362:CDC37 protein, human; C513271:Cdc37 protein, mouse; D018797:Cell Cycle Proteins; D018841:HSP90 Heat-Shock Proteins; C107835:Hspca protein, mouse; D047029:Lactams, Macrocyclic; D018832:Molecular Chaperones; D046912:Multiprotein Complexes; D011994:Recombinant Proteins; C112765:tanespimycin; D048308:Mitogen-Activated Protein Kinase 14; D048371:MAP Kinase Kinase 3; D018833:Chaperonins; C001277:geldanamycin