Regular voluntary exercise cures stress-induced impairment of cognitive function and cell proliferation accompanied by increases in cerebral IGF-1 and GST activity in mice.
Nakajima
Sanae
S
Department of Biochemistry and Cell Biology, Institute of Gerontology, Nippon Medical School, Kawasaki, Kanagawa 211-8533, Japan.
Ohsawa
Ikuroh
I
Ohta
Shigeo
S
Ohno
Makoto
M
Mikami
Toshio
T
D000222:Adaptation, Physiological; D000818:Animals; D049109:Cell Proliferation; D002540:Cerebral Cortex / Q000166:cytology / Q000378:metabolism; D003071:Cognition / Q000502:physiology; D018891:Dentate Gyrus / Q000166:cytology* / Q000502:physiology; D005982:Glutathione Transferase / Q000378:metabolism*; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D007334:Insulin-Like Growth Factor I / Q000235:genetics / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D018782:Maze Learning / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D055495:Neurogenesis / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000502:physiology*; D012333:RNA, Messenger / Q000032:analysis; D011897:Random Allocation; D013315:Stress, Psychological / Q000378:metabolism
D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I; D005982:Glutathione Transferase