title: HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy.
authors.affiliation: Laboratory of Cancer Biology, Medical Sciences Division, University of Oxford, Oxford OX3 7DQ, United Kingdom.
authors.forename: Omar
authors.initials: O
authors.lastname: Khan
authors.forename: Susan
authors.initials: S
authors.lastname: Fotheringham
authors.forename: Victoria
authors.initials: V
authors.lastname: Wood
authors.forename: Lindsay
authors.initials: L
authors.lastname: Stimson
authors.forename: Chunlei
authors.initials: C
authors.lastname: Zhang
authors.forename: Francesco
authors.initials: F
authors.lastname: Pezzella
authors.forename: Madeleine
authors.initials: M
authors.lastname: Duvic
authors.forename: David J
authors.initials: DJ
authors.lastname: Kerr
authors.forename: Nicholas B
authors.initials: NB
authors.lastname: La Thangue
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D015415:Biomarkers / Q000378:metabolism; D001706:Biopsy; D045744:Cell Line, Tumor; D017322:Clinical Trials, Phase II as Topic; D045643:DNA Repair Enzymes / Q000235:genetics / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D034741:RNA, Small Interfering / Q000235:genetics; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers; D004268:DNA-Binding Proteins; D056572:Histone Deacetylase Inhibitors; C513287:RAD23B protein, human; D034741:RNA, Small Interfering; D046988:Proteasome Endopeptidase Complex; D045643:DNA Repair Enzymes