Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme.
Wösten-van Asperen
Roelie M
RM
Department of Pediatric Intensive Care, Emma Children's Hospital/Academic Medical Center, Amsterdam, The Netherlands. r.m.vanasperen@amc.uva.nl
Lutter
René
R
Specht
Patricia A C
PA
van Woensel
Job B
JB
van der Loos
Chris M
CM
Florquin
Sandrine
S
Lachmann
Burkhard
B
Bos
Albert P
AP
D000818:Animals; D001992:Bronchoalveolar Lavage Fluid; D002216:Captopril / Q000494:pharmacology; D054426:Chemokine CXCL2 / Q000378:metabolism*; D007249:Inflammation; D016753:Interleukin-10 / Q000378:metabolism; D053583:Interleukin-1beta / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D008070:Lipopolysaccharides / Q000378:metabolism*; D019808:Losartan / Q000494:pharmacology; D008168:Lung / Q000201:enzymology / Q000473:pathology*; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012121:Respiration, Artificial / Q000009:adverse effects*
D054426:Chemokine CXCL2; C513296:Cxcl2 protein, rat; D053583:Interleukin-1beta; D015850:Interleukin-6; D008070:Lipopolysaccharides; D016753:Interleukin-10; D002216:Captopril; D007703:Peptidyl-Dipeptidase A; D019808:Losartan