Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.
Rowe
Jenny
J
Department of Microbiology and Immunology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. rowej@upstate.edu
Greenblatt
Rebecca J
RJ
Liu
Dongmei
D
Moffat
Jennifer F
JF
D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000494:pharmacology*; D002470:Cell Survival; D002478:Cells, Cultured; D002644:Chickenpox / Q000188:drug therapy; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors*; D004279:DNA, Viral / Q000032:analysis; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004791:Enzyme Inhibitors / Q000008:administration & dosage* / Q000494:pharmacology*; D005347:Fibroblasts / Q000821:virology; D014645:Herpesvirus 3, Human / Q000254:growth & development / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D008163:Luminescent Measurements; D051379:Mice; D016513:Mice, SCID; D009499:Neutral Red / Q000378:metabolism; D009924:Organ Culture Techniques; D012867:Skin / Q000821:virology; D013194:Staining and Labeling / Q000379:methods; D010948:Viral Plaque Assay; D014779:Virus Replication
D000998:Antiviral Agents; D004279:DNA, Viral; D004791:Enzyme Inhibitors; D009499:Neutral Red; D018844:Cyclin-Dependent Kinases