Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.
Raaijmakers
Marc H G P
MH
Center for Regenerative Medicine, Massachusetts General Hospital and Harvard Medical School CPZN, USA. hraaijmakers@partners.org
Mukherjee
Siddhartha
S
Guo
Shangqin
S
Zhang
Siyi
S
Kobayashi
Tatsuya
T
Schoonmaker
Jesse A
JA
Ebert
Benjamin L
BL
Al-Shahrour
Fatima
F
Hasserjian
Robert P
RP
Scadden
Edward O
EO
Aung
Zinmar
Z
Matza
Marc
M
Merkenschlager
Matthias
M
Lin
Charles
C
Rommens
Johanna M
JM
Scadden
David T
DT
D000818:Animals; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D019070:Cell Lineage; D005260:Female; D017353:Gene Deletion; D006410:Hematopoiesis / Q000235:genetics; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008648:Mesoderm / Q000166:cytology; D051379:Mice; D009190:Myelodysplastic Syndromes / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D010006:Osteoblasts / Q000378:metabolism / Q000473:pathology; D010641:Phenotype; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D043244:Ribonuclease III / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D023981:Sarcoma, Myeloid / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D055153:Stem Cell Niche / Q000378:metabolism / Q000473:pathology; D013234:Stem Cells / Q000378:metabolism / Q000473:pathology*; D017154:Stromal Cells / Q000378:metabolism / Q000473:pathology
D011506:Proteins; C513661:Sbds protein, mouse; D043244:Ribonuclease III