Tanshinone IIA enhances BMP-2-stimulated commitment of C2C12 cells into osteoblasts via p38 activation.
Kim
Hye Joo
HJ
Laboratory of Chemical Genomics, Pharmacology Research Center, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon, 305-600, Korea.
Kim
Seong Hwan
SH
D045784:Abietanes; D000818:Animals; D055396:Bone Morphogenetic Protein 2 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D002352:Carrier Proteins / Q000494:pharmacology; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D007093:Imidazoles / Q000494:pharmacology; D051379:Mice; D015394:Molecular Structure; D010006:Osteoblasts / Q000187:drug effects / Q000378:metabolism*; D010012:Osteogenesis / Q000187:drug effects; D010616:Phenanthrenes / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000494:pharmacology*; D011725:Pyridines / Q000494:pharmacology; D013329:Structure-Activity Relationship; D048051:p38 Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000099176:Noggin Protein
D045784:Abietanes; D055396:Bone Morphogenetic Protein 2; D002352:Carrier Proteins; D007093:Imidazoles; D010616:Phenanthrenes; D011725:Pyridines; D048051:p38 Mitogen-Activated Protein Kinases; D000099176:Noggin Protein; C525719:Bmp2 protein, mouse; C021751:tanshinone; C090942:4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole