p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.
Cazzalini
Ornella
O
Dipartimento di Medicina Sperimentale, Università di Pavia, Pavia, Italy.
Donà
Francesca
F
Savio
Monica
M
Tillhon
Micol
M
Maccario
Cristina
C
Perucca
Paola
P
Stivala
Lucia A
LA
Scovassi
A Ivana
AI
Prosperi
Ennio
E
D000246:Adenosine Diphosphate Ribose / Q000096:biosynthesis; D000477:Alkylating Agents / Q000494:pharmacology; D000818:Animals; D002843:Chromatin / Q000378:metabolism; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004249:DNA Damage / Q000187:drug effects; D004260:DNA Repair; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D017353:Gene Deletion; D006367:HeLa Cells; D006657:Histones / Q000378:metabolism; D006801:Humans; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology; D051379:Mice; D010766:Phosphorylation; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism*
D000477:Alkylating Agents; D002843:Chromatin; D050759:Cyclin-Dependent Kinase Inhibitor p21; D006657:Histones; D008769:Methylnitronitrosoguanidine; D000246:Adenosine Diphosphate Ribose; D004247:DNA; C499321:Parp1 protein, mouse; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases