A structure-activity study to identify novel and efficient substrates of the human semicarbazide-sensitive amine oxidase/VAP-1 enzyme.
Bonaiuto
Emanuela
E
Department of Biological Chemistry, University of Padova, Via G. Colombo, 3, 35131 Padova, Italy.
Lunelli
Michele
M
Scarpa
Marina
M
Vettor
Roberto
R
Milan
Gabriella
G
Di Paolo
Maria Luisa
ML
D017667:Adipocytes / Q000166:cytology / Q000378:metabolism; D006631:Amine Oxidase (Copper-Containing) / Q000737:chemistry / Q000378:metabolism*; D000588:Amines / Q000737:chemistry / Q000378:metabolism; D002073:Butanes / Q000737:chemistry / Q000378:metabolism; D020134:Catalytic Domain; D015815:Cell Adhesion Molecules / Q000737:chemistry / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D055808:Drug Discovery; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008958:Models, Molecular; D009994:Osmolar Concentration; D011485:Protein Binding; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D012663:Semicarbazides / Q000378:metabolism*; D013329:Structure-Activity Relationship
D000588:Amines; D002073:Butanes; D015815:Cell Adhesion Molecules; D011994:Recombinant Proteins; D012663:Semicarbazides; C046888:butane; C076668:AOC3 protein, human; D006631:Amine Oxidase (Copper-Containing)