Methimazole-induced hypothyroidism causes alteration of the REDOX environment, oxidative stress, and hepatic damage; events not caused by hypothyroidism itself.
Cano-Europa
Edgar
E
Laboratorio de Neurobiología, Escuela Nacional de Ciencias Biológicas, I.P.N. México, DF, México.
Blas-Valdivia
Vanessa
V
Lopez-Galindo
Gabriel Eduardo
GE
Franco-Colin
Margarita
M
Pineda-Reynoso
Marisol
M
Hernandez-Garcia
Adelaida
A
Ortiz-Butron
Rocio
R
D000818:Animals; D002374:Catalase / Q000378:metabolism; D004195:Disease Models, Animal; D006965:Hyperplasia; D007037:Hypothyroidism / Q000139:chemically induced* / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000502:physiology; D008099:Liver / Q000201:enzymology* / Q000473:pathology*; D008297:Male; D008713:Methimazole / Q000009:adverse effects*; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D013963:Thyroid Hormones / Q000097:blood; D013965:Thyroidectomy
D017382:Reactive Oxygen Species; D013963:Thyroid Hormones; D008713:Methimazole; D002374:Catalase; D013482:Superoxide Dismutase