title: Dose ranging for trials through biomarkers of drug effects.
authors.affiliation: Merck Research Laboratories.
authors.forename: W Z
authors.initials: WZ
authors.lastname: Potter
mesh_terms: D000544:Alzheimer Disease / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D016229:Amyloid beta-Peptides / Q000134:cerebrospinal fluid*; D015415:Biomarkers / Q000134:cerebrospinal fluid; D001921:Brain / Q000473:pathology*; D002986:Clinical Trials as Topic / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D018697:Nootropic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D049268:Positron-Emission Tomography
chemical_list: D016229:Amyloid beta-Peptides; D015415:Biomarkers; D018697:Nootropic Agents