title: SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies.
authors.affiliation: EMD Serono Research Center, Billerica, MA 01821, USA.
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Davis
authors.forename: Christel
authors.initials: C
authors.lastname: Aperlo
authors.forename: Yue
authors.initials: Y
authors.lastname: Li
authors.forename: Emmi
authors.initials: E
authors.lastname: Kurosawa
authors.forename: Yan
authors.initials: Y
authors.lastname: Lan
authors.forename: Kin-Ming
authors.initials: KM
authors.lastname: Lo
authors.forename: James S
authors.initials: JS
authors.lastname: Huston
mesh_terms: D000595:Amino Acid Sequence; D018033:Antibodies, Bispecific / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D000911:Antibodies, Monoclonal / Q000235:genetics / Q000378:metabolism; D000918:Antibody Specificity; D019281:Dimerization; D007141:Immunoglobulin Fc Fragments / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D007074:Immunoglobulin G / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015202:Protein Engineering / Q000379:methods*; D011993:Recombinant Fusion Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment
chemical_list: D018033:Antibodies, Bispecific; D000911:Antibodies, Monoclonal; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D011993:Recombinant Fusion Proteins