Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.
Pasapera
Ana M
AM
Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Schneider
Ian C
IC
Rericha
Erin
E
Schlaepfer
David D
DD
Waterman
Clare M
CM
D000577:Amides / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D005109:Extracellular Matrix / Q000378:metabolism; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D005353:Fibronectins / Q000494:pharmacology; D022001:Focal Adhesions / Q000378:metabolism*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000494:pharmacology; D051379:Mice; D024462:Myosin Type II / Q000037:antagonists & inhibitors / Q000378:metabolism*; D051419:Paxillin / Q000378:metabolism*; D010766:Phosphorylation; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology; D013329:Structure-Activity Relationship; D016596:Vinculin / Q000378:metabolism*
D000577:Amides; D005353:Fibronectins; D006576:Heterocyclic Compounds, 4 or More Rings; D051419:Paxillin; D011725:Pyridines; D016596:Vinculin; C108830:Y 27632; C472645:blebbistatin; D011505:Protein-Tyrosine Kinases; D024462:Myosin Type II