Norepinephrine transporter occupancy by antidepressant in human brain using positron emission tomography with (S,S)-[18F]FMeNER-D2.
Sekine
Mizuho
M
Molecular Neuroimaging Group, Molecular Imaging Center, National Institute of Radiological Sciences, 4-9-1, Anagawa, Inage-ku, Chiba, 263-8555, Japan. sekine@nirs.go.jp
Arakawa
Ryosuke
R
Ito
Hiroshi
H
Okumura
Masaki
M
Sasaki
Takeshi
T
Takahashi
Hidehiko
H
Takano
Harumasa
H
Okubo
Yoshiro
Y
Halldin
Christer
C
Suhara
Tetsuya
T
D000328:Adult; D000928:Antidepressive Agents / Q000378:metabolism* / Q000494:pharmacology; D001921:Brain / Q000000981:diagnostic imaging / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005462:Fluorine Radioisotopes / Q000378:metabolism*; D006801:Humans; D008297:Male; D009025:Morpholines / Q000378:metabolism*; D050484:Norepinephrine Plasma Membrane Transport Proteins / Q000378:metabolism*; D009661:Nortriptyline / Q000378:metabolism / Q000494:pharmacology; D049268:Positron-Emission Tomography / Q000379:methods; D011485:Protein Binding / Q000187:drug effects / Q000502:physiology; D055815:Young Adult
C506462:2-(alpha-(2-fluoromethoxyphenoxy)benzyl)morpholine; D000928:Antidepressive Agents; D005462:Fluorine Radioisotopes; D009025:Morpholines; D050484:Norepinephrine Plasma Membrane Transport Proteins; D009661:Nortriptyline