Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.
Beerman
Isabel
I
Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.
Bhattacharya
Deepta
D
Zandi
Sasan
S
Sigvardsson
Mikael
M
Weissman
Irving L
IL
Bryder
David
D
Rossi
Derrick J
DJ
D000375:Aging / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D006410:Hematopoiesis / Q000276:immunology / Q000502:physiology*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000145:classification / Q000166:cytology* / Q000276:immunology / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D008954:Models, Biological; D038042:Myelopoiesis; D011956:Receptors, Cell Surface / Q000378:metabolism; D000071177:Signaling Lymphocytic Activation Molecule Family Member 1
D015703:Antigens, CD; D011956:Receptors, Cell Surface; D000071177:Signaling Lymphocytic Activation Molecule Family Member 1