Activation of the P2X(7) receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages.
Corrêa
Gladys
G
Laboratory of Immunophysiology, Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. 21941-902 Rio de Janeiro, Brazil.
Marques da Silva
Camila
C
de Abreu Moreira-Souza
Aline Cristina
AC
Vommaro
Rossiane Claudia
RC
Coutinho-Silva
Robson
R
D000255:Adenosine Triphosphate / Q000031:analogs & derivatives / Q000378:metabolism; D000818:Animals; D000953:Antigens, Protozoan / Q000378:metabolism; D005260:Female; D007150:Immunohistochemistry; D008018:Life Cycle Stages / Q000502:physiology; D051907:Lysosomal Membrane Proteins / Q000378:metabolism; D017737:Macrophages, Peritoneal / Q000276:immunology / Q000378:metabolism* / Q000469:parasitology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009569:Nitric Oxide / Q000378:metabolism; D015800:Protozoan Proteins / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D018048:Receptors, Purinergic P2 / Q000276:immunology / Q000378:metabolism*; D058486:Receptors, Purinergic P2X7; D015398:Signal Transduction; D014122:Toxoplasma / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D014123:Toxoplasmosis / Q000276:immunology / Q000469:parasitology; D014617:Vacuoles / Q000378:metabolism / Q000469:parasitology; D052118:Lysosomal-Associated Membrane Protein 1
D000255:Adenosine Triphosphate; D000953:Antigens, Protozoan; D051907:Lysosomal Membrane Proteins; D009569:Nitric Oxide; D015800:Protozoan Proteins; D017382:Reactive Oxygen Species; D018048:Receptors, Purinergic P2; D058486:Receptors, Purinergic P2X7; C052255:Lamp1 protein, mouse; D052118:Lysosomal-Associated Membrane Protein 1; C546469:P2rx7 protein, mouse; C047168:SAG1 antigen, Toxoplasma; C033901:3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate