Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.
Le Deley
Marie-Cecile
MC
Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Zimmermannplatz 10, 1090 Vienna, Austria.
Delattre
Olivier
O
Schaefer
Karl-Ludwig
KL
Burchill
Sue A
SA
Koehler
Gabriele
G
Hogendoorn
Pancras C W
PC
Lion
Thomas
T
Poremba
Christopher
C
Marandet
Julien
J
Ballet
Stelly
S
Pierron
Gaelle
G
Brownhill
Samantha C
SC
Nesslböck
Michaela
M
Ranft
Andreas
A
Dirksen
Uta
U
Oberlin
Odile
O
Lewis
Ian J
IJ
Craft
Alan W
AW
Jürgens
Heribert
H
Kovar
Heinrich
H
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001859:Bone Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology / Q000628:therapy; D016009:Chi-Square Distribution; D018450:Disease Progression; D005060:Europe; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D009364:Neoplasm Recurrence, Local; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D016612:Paraffin Embedding; D010641:Phenotype; D016016:Proportional Hazards Models; D011446:Prospective Studies; D051789:Proto-Oncogene Protein c-fli-1 / Q000235:genetics*; D034802:RNA-Binding Protein EWS; D018714:Radiotherapy, Adjuvant; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D012307:Risk Factors; D012512:Sarcoma, Ewing / Q000235:genetics* / Q000401:mortality / Q000556:secondary / Q000628:therapy; D033581:Stem Cell Transplantation; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics*; D016896:Treatment Outcome; D055815:Young Adult
C450460:EWS-ERG fusion protein, human; C106031:EWS-FLI fusion protein; D015514:Oncogene Proteins, Fusion; D051789:Proto-Oncogene Protein c-fli-1; D034802:RNA-Binding Protein EWS; D014157:Transcription Factors