Synthesis, molecular modeling and biological evaluation of PSB as targeted antibiotics.
Cheng
Kui
K
State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, People's Republic of China.
Zheng
Qing-Zhong
QZ
Hou
Jin
J
Zhou
Yang
Y
Liu
Chang-Hong
CH
Zhao
Jing
J
Zhu
Hai-Liang
HL
D015099:3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / Q000037:antagonists & inhibitors; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000201:enzymology*; D020134:Catalytic Domain / Q000187:drug effects; D019295:Computational Biology; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology; D007202:Indicators and Reagents; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D010455:Peptides / Q000138:chemical synthesis* / Q000494:pharmacology*; D011485:Protein Binding; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D007202:Indicators and Reagents; D008024:Ligands; D010455:Peptides; D012545:Schiff Bases; C077402:3-ketoacyl-acyl carrier protein synthase III; D015099:3-Oxoacyl-(Acyl-Carrier-Protein) Synthase