title: Unexpected roles for DEAD-box protein 3 in viral RNA sensing pathways.
authors.affiliation: School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Orla
authors.initials: O
authors.lastname: Mulhern
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Bowie
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000276:immunology* / Q000378:metabolism; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D055785:Gene Knockdown Techniques; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology; D000072640:Interferon-Induced Helicase, IFIH1; D016899:Interferon-beta / Q000096:biosynthesis* / Q000235:genetics; D018448:Models, Immunological; D046912:Multiprotein Complexes; D011070:Poly I-C / Q000494:pharmacology; D011485:Protein Binding; D012367:RNA, Viral / Q000276:immunology*; D011971:Receptors, Immunologic; D011993:Recombinant Fusion Proteins / Q000276:immunology; D015398:Signal Transduction; D014779:Virus Replication
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D007369:Interferon Inducers; C505371:MAVS protein, human; D046912:Multiprotein Complexes; D012367:RNA, Viral; D011971:Receptors, Immunologic; D011993:Recombinant Fusion Proteins; D016899:Interferon-beta; C119332:DDX3X protein, human; C452820:RIGI protein, human; C452815:IFIH1 protein, human; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases; D000072640:Interferon-Induced Helicase, IFIH1; D011070:Poly I-C