title: B-Raf kinase inhibitors: hit enrichment through scaffold hopping.
authors.affiliation: Chemical Sciences, Wyeth Research, Pearl River, NY 10965, USA. gopalsa@wyeth.com
authors.forename: Ariamala
authors.initials: A
authors.lastname: Gopalsamy
authors.forename: Mengxiao
authors.initials: M
authors.lastname: Shi
authors.forename: Yongbo
authors.initials: Y
authors.lastname: Hu
authors.forename: Frederick
authors.initials: F
authors.lastname: Lee
authors.forename: Larry
authors.initials: L
authors.lastname: Feldberg
authors.forename: Eileen
authors.initials: E
authors.lastname: Frommer
authors.forename: Steven
authors.initials: S
authors.lastname: Kim
authors.forename: Karen
authors.initials: K
authors.lastname: Collins
authors.forename: Donald
authors.initials: D
authors.lastname: Wojciechowicz
authors.forename: Robert
authors.initials: R
authors.lastname: Mallon
mesh_terms: D008958:Models, Molecular; D047428:Protein Kinase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors*; D011743:Pyrimidines / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D048493:Proto-Oncogene Proteins B-raf