title: High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities.
authors.affiliation: Erasmus University Medical Center, Department of Hematology, Dr Molewaterplein 50, 3015 GE Rotterdam, the Netherlands.
authors.forename: Stefan
authors.initials: S
authors.lastname: Gröschel
authors.forename: Sanne
authors.initials: S
authors.lastname: Lugthart
authors.forename: Richard F
authors.initials: RF
authors.lastname: Schlenk
authors.forename: Peter J M
authors.initials: PJ
authors.lastname: Valk
authors.forename: Karina
authors.initials: K
authors.lastname: Eiwen
authors.forename: Chantal
authors.initials: C
authors.lastname: Goudswaard
authors.forename: Wim J L
authors.initials: WJ
authors.lastname: van Putten
authors.forename: Sabine
authors.initials: S
authors.lastname: Kayser
authors.forename: Leo F
authors.initials: LF
authors.lastname: Verdonck
authors.forename: Michael
authors.initials: M
authors.lastname: Lübbert
authors.forename: Gert-Jan
authors.initials: GJ
authors.lastname: Ossenkoppele
authors.forename: Ulrich
authors.initials: U
authors.lastname: Germing
authors.forename: Ingo
authors.initials: I
authors.lastname: Schmidt-Wolf
authors.forename: Brigitte
authors.initials: B
authors.lastname: Schlegelberger
authors.forename: Jürgen
authors.initials: J
authors.lastname: Krauter
authors.forename: Arnold
authors.initials: A
authors.lastname: Ganser
authors.forename: Hartmut
authors.initials: H
authors.lastname: Döhner
authors.forename: Bob
authors.initials: B
authors.lastname: Löwenberg
authors.forename: Konstanze
authors.initials: K
authors.lastname: Döhner
authors.forename: Ruud
authors.initials: R
authors.lastname: Delwel
mesh_terms: D000293:Adolescent; D000328:Adult; D002880:Chromosomes, Human, Pair 11; D002897:Chromosomes, Human, Pair 7; D020732:Cytogenetic Analysis; D004268:DNA-Binding Proteins / Q000235:genetics*; D018572:Disease-Free Survival; D005060:Europe; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D053208:Kaplan-Meier Estimate; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000401:mortality / Q000473:pathology / Q000628:therapy; D016015:Logistic Models; D000074008:MDS1 and EVI1 Complex Locus Protein; D008297:Male; D008875:Middle Aged; D009006:Monosomy; D000090243:Nucleophosmin; D016017:Odds Ratio; D016133:Polymerase Chain Reaction; D016016:Proportional Hazards Models; D011519:Proto-Oncogenes / Q000235:genetics*; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D033581:Stem Cell Transplantation; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics*; D014178:Translocation, Genetic; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D015854:Up-Regulation; D055815:Young Adult
chemical_list: D004268:DNA-Binding Proteins; D000074008:MDS1 and EVI1 Complex Locus Protein; C063575:MECOM protein, human; C000716967:NPM1 protein, human; D014157:Transcription Factors; D000090243:Nucleophosmin