Phosphodiesterase signaling system is disrupted in the cerebella of subjects with schizophrenia, bipolar disorder, and major depression.
Fatemi
S Hossein
SH
Folsom
Timothy D
TD
Reutiman
Teri J
TJ
Vazquez
Gabriela
G
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000235:genetics; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D000199:Actins / Q000235:genetics; D001714:Bipolar Disorder / Q000235:genetics* / Q000473:pathology* / Q000523:psychology; D002531:Cerebellum / Q000473:pathology*; D000242:Cyclic AMP / Q000235:genetics; D003865:Major Depressive Disorder / Q000235:genetics* / Q000473:pathology* / Q000523:psychology; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D008869:Microtubule-Associated Proteins / Q000235:genetics; D009473:Neuronal Plasticity / Q000235:genetics; D010727:Phosphoric Diester Hydrolases / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012559:Schizophrenia / Q000235:genetics* / Q000473:pathology*; D012565:Schizophrenic Psychology; D015398:Signal Transduction / Q000235:genetics*; D015854:Up-Regulation / Q000235:genetics
D000199:Actins; D007527:Isoenzymes; D008869:Microtubule-Associated Proteins; C525094:Nde1 protein, human; D012333:RNA, Messenger; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; C468781:PDE8B protein, human; D015106:3',5'-Cyclic-GMP Phosphodiesterases; C406737:PDE11A protein, human