Pathology Working Group review and evaluation of proliferative lesions of mammary gland tissues in female rats fed ammonium perfluorooctanoate (APFO) in the diet for 2 years.
Hardisty
Jerry F
JF
Experimental Pathology Laboratories, Research Triangle Park, North Carolina, USA.
Willson
Gabrielle A
GA
Brown
W Ray
WR
McConnell
Ernest E
EE
Frame
Steven R
SR
Gaylor
David W
DW
Kennedy
Gerald L
GL
Butenhoff
John L
JL
D000230:Adenocarcinoma / Q000139:chemically induced* / Q000473:pathology; D000236:Adenoma / Q000139:chemically induced* / Q000473:pathology; D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002210:Caprylates / Q000633:toxicity*; D049109:Cell Proliferation / Q000187:drug effects; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D018226:Fibroadenoma / Q000139:chemically induced* / Q000473:pathology; D005466:Fluorocarbons / Q000633:toxicity*; D006965:Hyperplasia / Q000139:chemically induced / Q000473:pathology; D008321:Mammary Glands, Animal / Q000187:drug effects* / Q000473:pathology; D015674:Mammary Neoplasms, Animal / Q000139:chemically induced* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced* / Q000473:pathology; D011230:Precancerous Conditions / Q000139:chemically induced / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley
D002210:Caprylates; D004785:Environmental Pollutants; D005466:Fluorocarbons; C023036:perfluorooctanoic acid