Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development.
Touboul
Thomas
T
Institut National de la Santé et de la Recherche Médicale, INSERM, Unite 972, IFR 93, Bicêtre Hospital, Kremlin-Bicêtre, France. [corrected]
Hannan
Nicholas R F
NR
Corbineau
Sébastien
S
Martinez
Amélie
A
Martinet
Clémence
C
Branchereau
Sophie
S
Mainot
Sylvie
S
Strick-Marchand
Hélène
H
Pedersen
Roger
R
Di Santo
James
J
Weber
Anne
A
Vallier
Ludovic
L
D028341:Activins / Q000494:pharmacology; D000818:Animals; D001549:Benzamides / Q000494:pharmacology; D055415:Bone Morphogenetic Protein 4 / Q000494:pharmacology; D002454:Cell Differentiation / Q000502:physiology; D002867:Chromones / Q000494:pharmacology; D004149:Dioxoles / Q000494:pharmacology; D053595:Embryonic Stem Cells / Q000166:cytology*; D016222:Fibroblast Growth Factor 2 / Q000494:pharmacology; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects; D022781:Hepatocytes / Q000166:cytology*; D006801:Humans; D008099:Liver / Q000196:embryology*; D051379:Mice; D009025:Morpholines / Q000494:pharmacology; D039904:Pluripotent Stem Cells / Q000166:cytology; D014212:Tretinoin / Q000494:pharmacology
C459179:4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide; D001549:Benzamides; D055415:Bone Morphogenetic Protein 4; D002867:Chromones; D004149:Dioxoles; D009025:Morpholines; D016222:Fibroblast Growth Factor 2; D028341:Activins; C085911:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; D014212:Tretinoin