The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms.
Jones
Amy V
AV
Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, United Kingdom.
Campbell
Peter J
PJ
Beer
Philip A
PA
Schnittger
Susanne
S
Vannucchi
Alessandro M
AM
Zoi
Katerina
K
Percy
Melanie J
MJ
McMullin
Mary Frances
MF
Scott
Linda M
LM
Tapper
William
W
Silver
Richard T
RT
Oscier
David
D
Harrison
Claire N
CN
Grallert
Harald
H
Kisialiou
Aliaksei
A
Strike
Paul
P
Chase
Andrew J
AJ
Green
Anthony R
AR
Cross
Nicholas C P
NC
D000328:Adult; D000368:Aged; D019943:Amino Acid Substitution; D001483:Base Sequence; D016022:Case-Control Studies; D015331:Cohort Studies; D017931:DNA Primers / Q000235:genetics; D005091:Exons; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006239:Haplotypes; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics*; D015810:Linkage Disequilibrium; D008297:Male; D008875:Middle Aged; D008957:Models, Genetic; D009154:Mutation; D020125:Mutation, Missense; D009196:Myeloproliferative Disorders / Q000235:genetics*; D011087:Polycythemia Vera / Q000235:genetics; D020641:Polymorphism, Single Nucleotide; D011446:Prospective Studies; D053628:Receptors, Thrombopoietin / Q000235:genetics*; D013920:Thrombocythemia, Essential / Q000188:drug therapy / Q000235:genetics
D017931:DNA Primers; D053628:Receptors, Thrombopoietin; C082218:MPL protein, human; C507924:JAK2 protein, human; D053614:Janus Kinase 2