12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells.
Krishnamoorthy
Sriram
S
Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48202, USA.
Jin
Rongxian
R
Cai
Yinlong
Y
Maddipati
Krishna Rao
KR
Nie
Daotai
D
Pagès
Gilles
G
Tucker
Stephanie C
SC
Honn
Kenneth V
KV
D001092:Arachidonate 12-Lipoxygenase / Q000378:metabolism*; D015687:Cell Hypoxia; D045744:Cell Line, Tumor; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000235:genetics / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D009389:Neovascularization, Pathologic; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000098:blood supply / Q000235:genetics* / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D014162:Transfection; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
C497442:HIF1A protein, human; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D012333:RNA, Messenger; D012334:RNA, Neoplasm; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D001092:Arachidonate 12-Lipoxygenase; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt