Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine.
Leger
Andrew J
AJ
Genzyme Corporation, 49 New York Avenue, Framingham, MA 01701-9322, USA. andrew.leger@genzyme.com
Altobelli
Allison
A
Mosquea
Leocadia M
LM
Belanger
Adam J
AJ
Song
Antonius
A
Cheng
Seng H
SH
Jiang
Canwen
C
Yew
Nelson S
NS
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects*; D002460:Cell Line; D003676:Deferoxamine / Q000494:pharmacology; D005260:Female; D005786:Gene Expression Regulation; D005998:Glycine / Q000737:chemistry / Q000494:pharmacology; D000860:Hypoxia / Q000378:metabolism; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000235:genetics / Q000378:metabolism; D016173:Macrophage Colony-Stimulating Factor / Q000378:metabolism; D051379:Mice; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D010010:Osteoclasts / Q000187:drug effects / Q000502:physiology; D011393:Procollagen-Proline Dioxygenase / Q000037:antagonists & inhibitors*; D053245:RANK Ligand / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D017262:Siderophores / Q000494:pharmacology; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D053245:RANK Ligand; D017262:Siderophores; D042461:Vascular Endothelial Growth Factor A; D016173:Macrophage Colony-Stimulating Factor; D011393:Procollagen-Proline Dioxygenase; D020928:Mitogen-Activated Protein Kinases; D003676:Deferoxamine; D005998:Glycine