Segmental amplification of MLL gene associated with high expression of AURKA and AURKB genes in a case of acute monoblastic leukemia with complex karyotype.
Oliveira
Fábio Morato de
FM
Departament of Internal Medicine, Faculty of Medicine of Ribeirão Preto and National Institute of Science and Technology in Stem Cell and Cell Therapy, Ribeirão Preto, Brazil. morato.oliveira@yahoo.com.br
Lucena-Araújo
Antônio Roberto
AR
Leite-Cueva
Sabrina D
SD
Santos
Guilherme Augusto S
GA
Rego
Eduardo M
EM
Falcão
Roberto P
RP
D000293:Adolescent; D064096:Aurora Kinase A; D064107:Aurora Kinase B; D064127:Aurora Kinases; D002869:Chromosome Aberrations; D005784:Gene Amplification; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000235:genetics; D008297:Male; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D014178:Translocation, Genetic; D015854:Up-Regulation
D051788:Myeloid-Lymphoid Leukemia Protein; C576917:AURKA protein, human; C576921:AURKB protein, human; D064096:Aurora Kinase A; D064107:Aurora Kinase B; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases