Soluble IL-7R alpha (sCD127) inhibits IL-7 activity and is increased in HIV infection.
Crawley
Angela M
AM
Ottawa Hospital Research Institute, ON, Canada.
Faucher
Sylvie
S
Angel
Jonathan B
JB
D002478:Cells, Cultured; D015658:HIV Infections / Q000276:immunology* / Q000378:metabolism*; D006801:Humans; D015851:Interleukin-7 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010766:Phosphorylation / Q000276:immunology; D051057:Proto-Oncogene Proteins c-akt / Q000037:antagonists & inhibitors / Q000502:physiology; D020395:Receptors, Interleukin-7 / Q000096:biosynthesis / Q000097:blood / Q000502:physiology*; D050799:STAT5 Transcription Factor / Q000037:antagonists & inhibitors / Q000502:physiology; D015398:Signal Transduction / Q000276:immunology; D012995:Solubility; D015854:Up-Regulation / Q000276:immunology*
C508605:IL7 protein, human; D015851:Interleukin-7; D020395:Receptors, Interleukin-7; D050799:STAT5 Transcription Factor; C415350:interleukin-7 receptor, alpha chain; D051057:Proto-Oncogene Proteins c-akt