Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice.
Kyttaris
Vasileios C
VC
Division of Rheumatology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, CLS-937, Boston, MA 02215, USA.
Zhang
Zheng
Z
Kuchroo
Vijay K
VK
Oukka
Mohamed
M
Tsokos
George C
GC
D000818:Animals; D001323:Autoantibodies / Q000096:biosynthesis / Q000378:metabolism; D002465:Cell Movement / Q000235:genetics / Q000276:immunology; D002478:Cells, Cultured; D003433:Crosses, Genetic; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D020022:Genetic Predisposition to Disease; D006965:Hyperplasia / Q000235:genetics / Q000276:immunology / Q000517:prevention & control; D018836:Inflammation Mediators / Q000037:antagonists & inhibitors / Q000378:metabolism; D020381:Interleukin-17 / Q000096:biosynthesis; D008181:Lupus Nephritis / Q000235:genetics / Q000276:immunology* / Q000473:pathology / Q000517:prevention & control*; D008221:Lymphoid Tissue / Q000166:cytology / Q000276:immunology / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D019463:Mice, Inbred MRL lpr; D018345:Mice, Knockout; D018123:Receptors, Interleukin / Q000172:deficiency* / Q000235:genetics*
D001323:Autoantibodies; D016207:Cytokines; C098680:Il17a protein, mouse; D018836:Inflammation Mediators; D020381:Interleukin-17; D018123:Receptors, Interleukin; C528688:interleukin-23 receptor, mouse