Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7.
Phillips
Rebecca
R
Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom.
Svensson
Mattias
M
Aziz
Naveed
N
Maroof
Asher
A
Brown
Najmeeyah
N
Beattie
Lynette
L
Signoret
Nathalie
N
Kaye
Paul M
PM
D000818:Animals; D015870:Gene Expression / Q000276:immunology; D050839:Interferon Regulatory Factor-7 / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D016898:Interferon-alpha / Q000276:immunology / Q000378:metabolism; D007371:Interferon-gamma / Q000276:immunology / Q000378:metabolism; D007893:Leishmania donovani / Q000276:immunology*; D007898:Leishmaniasis, Visceral / Q000276:immunology*; D008264:Macrophages / Q000166:cytology / Q000276:immunology* / Q000469:parasitology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009569:Nitric Oxide / Q000378:metabolism; D010588:Phagosomes / Q000276:immunology; D034741:RNA, Small Interfering; D013154:Spleen / Q000276:immunology / Q000469:parasitology
D050839:Interferon Regulatory Factor-7; D016898:Interferon-alpha; C494235:Irf7 protein, mouse; D034741:RNA, Small Interfering; D009569:Nitric Oxide; D007371:Interferon-gamma