title: Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-kappaB in cultured lung epithelial cells.
authors.affiliation: Department of Biochemistry, School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Mizutani
authors.forename: Noriko
authors.initials: N
authors.lastname: Maeda
authors.forename: Seikichi
authors.initials: S
authors.lastname: Toku
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Isohama
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Sugahara
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004847:Epithelial Cells / Q000187:drug effects* / Q000378:metabolism; D017930:Genes, Reporter; D006801:Humans; D020672:I-kappa B Proteins / Q000378:metabolism; D015151:Immunoblotting; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000187:drug effects* / Q000378:metabolism; D010766:Phosphorylation; D021381:Protein Transport; D011650:Pulmonary Alveoli / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D011773:Pyruvates / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D051996:Transcription Factor RelA / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D020672:I-kappa B Proteins; D016328:NF-kappa B; C000606204:NFKBIA protein, human; D011773:Pyruvates; D051996:Transcription Factor RelA; D014409:Tumor Necrosis Factor-alpha; C046522:ethyl pyruvate; D000072000:NF-KappaB Inhibitor alpha