Comparison of egg and high yielding MDCK cell-derived live attenuated influenza virus for commercial production of trivalent influenza vaccine: in vitro cell susceptibility and influenza virus replication kinetics in permissive and semi-permissive cells.
Hussain
Althaf I
AI
Cell Culture Process Development, MedImmune, LLC 3055 Patrick Henry Dr., Santa Clara, CA 95054, USA. hussaina@medimmune.com
Cordeiro
Melissa
M
Sevilla
Elizabeth
E
Liu
Jonathan
J
D000818:Animals; D045744:Cell Line, Tumor; D002645:Chickens; D004285:Dogs; D004531:Eggs / Q000821:virology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000254:growth & development* / Q000276:immunology / Q000502:physiology; D053122:Influenza A Virus, H3N2 Subtype / Q000254:growth & development* / Q000276:immunology / Q000502:physiology; D007252:Influenza Vaccines / Q000096:biosynthesis* / Q000276:immunology; D012367:RNA, Viral / Q000032:analysis; D014613:Vaccines, Attenuated / Q000096:biosynthesis / Q000276:immunology; D014779:Virus Replication
D007252:Influenza Vaccines; D012367:RNA, Viral; D014613:Vaccines, Attenuated