Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
Angyal
Adrienn
A
Section of Molecular Medicine, Department of Orthopedic Surgery, Rush University Medical Center, 1735 West Harrison Street, Chicago, IL 60612, USA.
Egelston
Colt
C
Kobezda
Tamás
T
Olasz
Katalin
K
László
Anna
A
Glant
Tibor T
TT
Mikecz
Katalin
K
D019264:Adoptive Transfer; D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology / Q000473:pathology; D001169:Arthritis, Experimental / Q000139:chemically induced / Q000276:immunology* / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000139:chemically induced / Q000276:immunology* / Q000473:pathology; D001323:Autoantibodies / Q000276:immunology*; D002465:Cell Movement; D005260:Female; D000068876:Fingolimod Hydrochloride; D055879:Gene Knock-In Techniques; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007596:Joints / Q000276:immunology* / Q000473:pathology; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D016513:Mice, SCID; D011409:Propylene Glycols / Q000494:pharmacology; D011509:Proteoglycans / Q000276:immunology* / Q000494:pharmacology; D013110:Sphingosine / Q000031:analogs & derivatives / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000473:pathology
D001323:Autoantibodies; D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D011509:Proteoglycans; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine