Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis.
Tarling
Elizabeth J
EJ
Department of Biological Chemistry, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095-1737, USA.
Bojanic
Dragana D
DD
Tangirala
Rajendra K
RK
Wang
Xuping
X
Lovgren-Sandblom
Anita
A
Lusis
Aldons J
AJ
Bjorkhem
Ingemar
I
Edwards
Peter A
PA
D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D000818:Animals; D001057:Apolipoproteins E / Q000172:deficiency* / Q000235:genetics; D017209:Apoptosis / Q000235:genetics; D050197:Atherosclerosis / Q000235:genetics / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D051023:BH3 Interacting Domain Death Agonist Protein / Q000235:genetics; D016026:Bone Marrow Transplantation; D001921:Brain / Q000378:metabolism / Q000473:pathology; D053148:Caspase 3 / Q000378:metabolism; D002478:Cells, Cultured; D002784:Cholesterol / Q000378:metabolism*; D004195:Disease Models, Animal; D005838:Genotype; D020287:In Situ Nick-End Labeling; D008074:Lipoproteins / Q000172:deficiency* / Q000235:genetics; D008077:Lipoproteins, LDL / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D010084:Oxidation-Reduction; D010641:Phenotype; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D013997:Time Factors
C487540:ABCG1 protein, mouse; D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters; D001057:Apolipoproteins E; D051023:BH3 Interacting Domain Death Agonist Protein; C494815:Bid protein, mouse; C111858:Bok protein, mouse; D008074:Lipoproteins; D008077:Lipoproteins, LDL; D019253:Proto-Oncogene Proteins c-bcl-2; D012333:RNA, Messenger; C099252:oxidized low density lipoprotein; D002784:Cholesterol; C505409:Casp3 protein, mouse; D053148:Caspase 3