Reaction rates and mechanism of the ascorbic acid oxidation by molecular oxygen facilitated by Cu(II)-containing amyloid-beta complexes and aggregates.
Jiang
Dianlu
D
Department of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, California 90032, USA.
Li
Xiangjun
X
Liu
Lin
L
Yagnik
Gargey B
GB
Zhou
Feimeng
F
D016229:Amyloid beta-Peptides / Q000737:chemistry* / Q000378:metabolism*; D000975:Antioxidants / Q000737:chemistry*; D001205:Ascorbic Acid / Q000737:chemistry*; D003300:Copper / Q000494:pharmacology*; D055664:Electrochemical Techniques; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism*; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism*; D055503:Protein Multimerization; D017382:Reactive Oxygen Species / Q000378:metabolism; D013054:Spectrophotometry, Atomic
D016229:Amyloid beta-Peptides; D000975:Antioxidants; D010446:Peptide Fragments; D017382:Reactive Oxygen Species; C075222:amyloid beta-protein (1-42); D003300:Copper; D006861:Hydrogen Peroxide; D001205:Ascorbic Acid; D010100:Oxygen