A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury.
Di
Anke
A
Department of Pharmacology, Center for Lung and Vascular Biology, University of Illinois, Chicago, Illinois 60612, USA. ankedi@uic.edu
Kawamura
Takeshi
T
Gao
Xiao-Pei
XP
Tang
Haiyang
H
Berdyshev
Evgeny
E
Vogel
Stephen M
SM
Zhao
You-Yang
YY
Sharma
Tiffany
T
Bachmaier
Kurt
K
Xu
Jingsong
J
Malik
Asrar B
AB
D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism; D000818:Animals; D015536:Down-Regulation / Q000235:genetics / Q000528:radiation effects; D004789:Enzyme Activation / Q000187:drug effects / Q000235:genetics; D008070:Lipopolysaccharides / Q000633:toxicity*; D008168:Lung / Q000201:enzymology*; D008246:Lysophospholipids / Q000235:genetics / Q000378:metabolism; D048670:MAP Kinase Kinase 4 / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D018345:Mice, Knockout; D019255:NADPH Oxidases / Q000235:genetics / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D009504:Neutrophils / Q000201:enzymology*; D016877:Oxidants / Q000378:metabolism; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000235:genetics / Q000378:metabolism*; D011014:Pneumonia / Q000139:chemically induced / Q000201:enzymology* / Q000235:genetics; D013110:Sphingosine / Q000031:analogs & derivatives / Q000235:genetics / Q000378:metabolism; D000099157:Sphingosine Kinase
D048868:Adaptor Proteins, Signal Transducing; D008070:Lipopolysaccharides; D008246:Lysophospholipids; D048670:MAP Kinase Kinase 4; D019255:NADPH Oxidases; D009419:Nerve Tissue Proteins; D016877:Oxidants; D017853:Phosphotransferases (Alcohol Group Acceptor); D013110:Sphingosine; D000099157:Sphingosine Kinase; C485750:MAPK8IP3 protein, human; C060506:sphingosine 1-phosphate