Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group.
van Doorninck
John A
JA
Childrens Hospital Los Angeles, 4650 Sunset Blvd, MS#57, Los Angeles, CA 90027, USA.
Ji
Lingyun
L
Schaub
Betty
B
Shimada
Hiroyuki
H
Wing
Michele R
MR
Krailo
Mark D
MD
Lessnick
Stephen L
SL
Marina
Neyssa
N
Triche
Timothy J
TJ
Sposto
Richard
R
Womer
Richard B
RB
Lawlor
Elizabeth R
ER
D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001859:Bone Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology / Q000628:therapy; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D018572:Disease-Free Survival; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D010641:Phenotype; D011446:Prospective Studies; D051789:Proto-Oncogene Protein c-fli-1 / Q000235:genetics*; D034802:RNA-Binding Protein EWS; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D012307:Risk Factors; D012512:Sarcoma, Ewing / Q000235:genetics* / Q000401:mortality / Q000556:secondary / Q000628:therapy; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics*; D016896:Treatment Outcome; D014481:United States; D055815:Young Adult
C450460:EWS-ERG fusion protein, human; C106031:EWS-FLI fusion protein; D015514:Oncogene Proteins, Fusion; D051789:Proto-Oncogene Protein c-fli-1; D034802:RNA-Binding Protein EWS; D014157:Transcription Factors