Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes.
Gonzalez
Santiago F
SF
The Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Lukacs-Kornek
Veronika
V
Kuligowski
Michael P
MP
Pitcher
Lisa A
LA
Degn
Søren E
SE
Kim
Young-A
YA
Cloninger
Mary J
MJ
Martinez-Pomares
Luisa
L
Gordon
Siamon
S
Turley
Shannon J
SJ
Carroll
Michael C
MC
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D017951:Antigen Presentation; D015815:Cell Adhesion Molecules / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D002465:Cell Movement; D002478:Cells, Cultured; D004002:Clodronic Acid / Q000008:administration & dosage; D050091:Dendrimers / Q000008:administration & dosage; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology / Q000378:metabolism* / Q000473:pathology / Q000821:virology; D004705:Endocytosis / Q000187:drug effects / Q000235:genetics; D056724:Immunity, Humoral / Q000187:drug effects / Q000235:genetics; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D016233:Immunotherapy, Active; D009980:Influenza A virus / Q000276:immunology* / Q000472:pathogenicity; D007252:Influenza Vaccines / Q000008:administration & dosage; D037181:Lectins, C-Type / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D008198:Lymph Nodes / Q000473:pathology / Q000821:virology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology / Q000378:metabolism* / Q000473:pathology / Q000821:virology; D037601:Mannose-Binding Lectin / Q000235:genetics / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D036641:Microscopy, Fluorescence, Multiphoton; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000517:prevention & control; D011956:Receptors, Cell Surface / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D000099215:DC-Specific ICAM-3 Grabbing Nonintegrin
D000914:Antibodies, Viral; D015815:Cell Adhesion Molecules; D004002:Clodronic Acid; D050091:Dendrimers; D007143:Immunoglobulin Heavy Chains; D007252:Influenza Vaccines; D037181:Lectins, C-Type; D037601:Mannose-Binding Lectin; D011956:Receptors, Cell Surface; D000099215:DC-Specific ICAM-3 Grabbing Nonintegrin