title: The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.
authors.affiliation: Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
authors.forename: Md Hasan
authors.initials: MH
authors.lastname: Zaki
authors.forename: Kelli L
authors.initials: KL
authors.lastname: Boyd
authors.forename: Peter
authors.initials: P
authors.lastname: Vogel
authors.forename: Michael B
authors.initials: MB
authors.lastname: Kastan
authors.forename: Mohamed
authors.initials: M
authors.lastname: Lamkanfi
authors.forename: Thirumala-Devi
authors.initials: TD
authors.lastname: Kanneganti
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins; D053468:CARD Signaling Adaptor Proteins; D002352:Carrier Proteins / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D049109:Cell Proliferation; D003092:Colitis / Q000139:chemically induced / Q000276:immunology* / Q000382:microbiology / Q000473:pathology*; D003598:Cytoskeletal Proteins / Q000276:immunology; D016264:Dextran Sulfate; D004195:Disease Models, Animal; D004847:Epithelial Cells / Q000166:cytology / Q000276:immunology*; D020382:Interleukin-18 / Q000096:biosynthesis / Q000276:immunology; D007408:Intestinal Absorption; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D015398:Signal Transduction
chemical_list: D051017:Apoptosis Regulatory Proteins; D053468:CARD Signaling Adaptor Proteins; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; D020382:Interleukin-18; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C492716:Nlrp3 protein, mouse; C498534:Pycard protein, mouse; D016264:Dextran Sulfate