title: 12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells.
authors.affiliation: Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48202, USA.
authors.forename: Sriram
authors.initials: S
authors.lastname: Krishnamoorthy
authors.forename: Rongxian
authors.initials: R
authors.lastname: Jin
authors.forename: Yinlong
authors.initials: Y
authors.lastname: Cai
authors.forename: Krishna Rao
authors.initials: KR
authors.lastname: Maddipati
authors.forename: Daotai
authors.initials: D
authors.lastname: Nie
authors.forename: Gilles
authors.initials: G
authors.lastname: Pagès
authors.forename: Stephanie C
authors.initials: SC
authors.lastname: Tucker
authors.forename: Kenneth V
authors.initials: KV
authors.lastname: Honn
mesh_terms: D001092:Arachidonate 12-Lipoxygenase / Q000378:metabolism*; D015687:Cell Hypoxia; D045744:Cell Line, Tumor; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000235:genetics / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D009389:Neovascularization, Pathologic; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000098:blood supply / Q000235:genetics* / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D014162:Transfection; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
chemical_list: C497442:HIF1A protein, human; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D012333:RNA, Messenger; D012334:RNA, Neoplasm; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D001092:Arachidonate 12-Lipoxygenase; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt