Exposure of human skin to benzo[a]pyrene: role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation.
Costa
C
C
Dip. Medicina Sociale del Territorio, Sez. Medicina del Lavoro-Università di Messina, A.O.U. Policlinico G. Martino, pad. H, via Consolare Valeria, 1 - 98125 Messina, Italy. ccosta@unime.it <ccosta@unime.it>
Catania
S
S
De Pasquale
R
R
Stancanelli
R
R
Scribano
G M
GM
Melchini
A
A
D001564:Benzo(a)pyrene / Q000494:pharmacology*; D015153:Blotting, Western; D019363:Cytochrome P-450 CYP1A1 / Q000235:genetics / Q000378:metabolism*; D005796:Genes / Q000187:drug effects; D006801:Humans; D015227:Lipid Peroxidation / Q000235:genetics; D018384:Oxidative Stress / Q000187:drug effects*; D011084:Polycyclic Aromatic Hydrocarbons / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D018336:Receptors, Aryl Hydrocarbon / Q000378:metabolism*; D012867:Skin / Q000378:metabolism*
D011084:Polycyclic Aromatic Hydrocarbons; D017382:Reactive Oxygen Species; D018336:Receptors, Aryl Hydrocarbon; D001564:Benzo(a)pyrene; D019363:Cytochrome P-450 CYP1A1