The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression.
Aubert
Grégory
G
Service of Endocrinology, Diabetology and Metabolism and Lausanne Center for Metabolic and Cardiovascular Diseases, University Hospital and Faculty of Biology and Medicine, 1011 Lausanne, Switzerland.
Mansuy
Virginie
V
Voirol
Marie-Jeanne
MJ
Pellerin
Luc
L
Pralong
François P
FP
D054369:Agouti-Related Protein / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000502:physiology; D004435:Eating / Q000187:drug effects*; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007031:Hypothalamus / Q000187:drug effects* / Q000378:metabolism*; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D008297:Male; D008687:Metformin / Q000494:pharmacology*; D009478:Neuropeptide Y / Q000378:metabolism; D009765:Obesity / Q000378:metabolism*; D011333:Pro-Opiomelanocortin / Q000378:metabolism; D012313:RNA / Q000737:chemistry / Q000235:genetics; D011897:Random Allocation; D051381:Rats; D020318:Rats, Long-Evans; D054411:Receptors, Leptin / Q000097:blood* / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018709:Statistics, Nonparametric
D054369:Agouti-Related Protein; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D020738:Leptin; D009478:Neuropeptide Y; D054411:Receptors, Leptin; D012313:RNA; D011333:Pro-Opiomelanocortin; D008687:Metformin