Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Dumont
Julie
J
Inserm U991, Faculté des Sciences Pharmaceutiques et Biologiques, F-35043 Rennes cedex, France. Julie.Dumont@pasteur-lille.fr
Jossé
Rozenn
R
Lambert
Carine
C
Anthérieu
Sébastien
S
Le Hegarat
Ludovic
L
Aninat
Caroline
C
Robin
Marie-Anne
MA
Guguen-Guillouzo
Christiane
C
Guillouzo
André
A
D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004249:DNA Damage; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007093:Imidazoles / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects; D016133:Polymerase Chain Reaction; D011810:Quinoxalines / Q000633:toxicity*
D007093:Imidazoles; D011810:Quinoxalines; C036990:2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline; D003577:Cytochrome P-450 Enzyme System; C049584:2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine