title: Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.
authors.affiliation: Center for Regenerative Medicine, Massachusetts General Hospital and Harvard Medical School CPZN, USA. hraaijmakers@partners.org
authors.forename: Marc H G P
authors.initials: MH
authors.lastname: Raaijmakers
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Shangqin
authors.initials: S
authors.lastname: Guo
authors.forename: Siyi
authors.initials: S
authors.lastname: Zhang
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Jesse A
authors.initials: JA
authors.lastname: Schoonmaker
authors.forename: Benjamin L
authors.initials: BL
authors.lastname: Ebert
authors.forename: Fatima
authors.initials: F
authors.lastname: Al-Shahrour
authors.forename: Robert P
authors.initials: RP
authors.lastname: Hasserjian
authors.forename: Edward O
authors.initials: EO
authors.lastname: Scadden
authors.forename: Zinmar
authors.initials: Z
authors.lastname: Aung
authors.forename: Marc
authors.initials: M
authors.lastname: Matza
authors.forename: Matthias
authors.initials: M
authors.lastname: Merkenschlager
authors.forename: Charles
authors.initials: C
authors.lastname: Lin
authors.forename: Johanna M
authors.initials: JM
authors.lastname: Rommens
authors.forename: David T
authors.initials: DT
authors.lastname: Scadden
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D019070:Cell Lineage; D005260:Female; D017353:Gene Deletion; D006410:Hematopoiesis / Q000235:genetics; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008648:Mesoderm / Q000166:cytology; D051379:Mice; D009190:Myelodysplastic Syndromes / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D010006:Osteoblasts / Q000378:metabolism / Q000473:pathology; D010641:Phenotype; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D043244:Ribonuclease III / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D023981:Sarcoma, Myeloid / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D055153:Stem Cell Niche / Q000378:metabolism / Q000473:pathology; D013234:Stem Cells / Q000378:metabolism / Q000473:pathology*; D017154:Stromal Cells / Q000378:metabolism / Q000473:pathology
chemical_list: D011506:Proteins; C513661:Sbds protein, mouse; D043244:Ribonuclease III