The CD4+ T-cell epitope-binding register is a critical parameter when generating functional HLA-DR tetramers with promiscuous peptides.
Cecconi
Virginia
V
Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.
Moro
Monica
M
Del Mare
Sara
S
Sidney
John
J
Bachi
Angela
A
Longhi
Renato
R
Sette
Alessandro
A
Protti
Maria Pia
MP
Dellabona
Paolo
P
Casorati
Giulia
G
D000951:Antigens, Neoplasm / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002460:Cell Line; D002469:Cell Separation; D018984:Epitopes, T-Lymphocyte / Q000276:immunology*; D005434:Flow Cytometry; D006684:HLA-DR Antigens / Q000276:immunology*; D006801:Humans; D009363:Neoplasm Proteins / Q000276:immunology*; D010446:Peptide Fragments / Q000276:immunology*; D016133:Polymerase Chain Reaction
D000951:Antigens, Neoplasm; D018984:Epitopes, T-Lymphocyte; D006684:HLA-DR Antigens; C072013:MAGEA3 protein, human; D009363:Neoplasm Proteins; D010446:Peptide Fragments