title: Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents.
authors.affiliation: Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.
authors.forename: Sreenath V
authors.initials: SV
authors.lastname: Sharma
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Haber
authors.forename: Jeff
authors.initials: J
authors.lastname: Settleman
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D045744:Cell Line, Tumor / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods / Q000592:standards; D004357:Drug Synergism; D066246:ErbB Receptors / Q000235:genetics; D020869:Gene Expression Profiling; D023281:Genomics / Q000379:methods; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D011237:Predictive Value of Tests; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D066246:ErbB Receptors