title: A novel nonsecosteroidal VDR agonist (CH5036249) exhibits efficacy in a spontaneous benign prostatic hyperplasia beagle model.
authors.affiliation: Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura Research Labs., 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan. taniguchiknj@chugai-pharm.co.jp
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: K
authors.initials: K
authors.lastname: Katagiri
authors.forename: H
authors.initials: H
authors.lastname: Kashiwagi
authors.forename: S
authors.initials: S
authors.lastname: Harada
authors.forename: Y
authors.initials: Y
authors.lastname: Sugimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
authors.forename: H
authors.initials: H
authors.lastname: Arakawa
authors.forename: T
authors.initials: T
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Yamazaki
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: A
authors.initials: A
authors.lastname: Kato
authors.forename: E
authors.initials: E
authors.lastname: Hoshino
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Esaki
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Takeda
authors.forename: F
authors.initials: F
authors.lastname: Ichikawa
authors.forename: A
authors.initials: A
authors.lastname: Harada
authors.forename: N
authors.initials: N
authors.lastname: Sekiguchi
authors.forename: M
authors.initials: M
authors.lastname: Ishigai
authors.forename: H
authors.initials: H
authors.lastname: Kawata
authors.forename: T
authors.initials: T
authors.lastname: Yoneya
authors.forename: E
authors.initials: E
authors.lastname: Onuma
authors.forename: M
authors.initials: M
authors.lastname: Sudoh
authors.forename: Y
authors.initials: Y
authors.lastname: Aoki
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000737:chemistry / Q000494:pharmacology*; D002118:Calcium / Q000097:blood; D049109:Cell Proliferation; D004195:Disease Models, Animal; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D015162:Micronucleus Tests; D008954:Models, Biological; D011467:Prostate / Q000187:drug effects / Q000378:metabolism; D011470:Prostatic Hyperplasia / Q000473:pathology*; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D018167:Receptors, Calcitriol / Q000819:agonists* / Q000378:metabolism; D017154:Stromal Cells / Q000166:cytology
chemical_list: D001559:Benzhydryl Compounds; C552205:CH 5036249; D011725:Pyridines; D018167:Receptors, Calcitriol; D002118:Calcium