title: The development and preliminary evaluation of a new Mycobacterium tuberculosis vaccine comprising Ag85b, HspX and CFP-10:ESAT-6 fusion protein with CpG DNA and aluminum hydroxide adjuvants.
authors.affiliation: School of Public Health, Shandong University, Ji'nan, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.forename: Miao
authors.initials: M
authors.lastname: Xu
authors.forename: Zhi-Yu
authors.initials: ZY
authors.lastname: Wang
authors.forename: Bao-Wen
authors.initials: BW
authors.lastname: Chen
authors.forename: Wei-Xin
authors.initials: WX
authors.lastname: Du
authors.forename: Cheng
authors.initials: C
authors.lastname: Su
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Shen
authors.forename: Ai-Hua
authors.initials: AH
authors.lastname: Zhao
authors.forename: Na
authors.initials: N
authors.lastname: Dong
authors.forename: Ya-Jun
authors.initials: YJ
authors.lastname: Wang
authors.forename: Guo-Zhi
authors.initials: GZ
authors.lastname: Wang
mesh_terms: D000217:Acyltransferases / Q000276:immunology*; D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000536:Aluminum Hydroxide / Q000008:administration & dosage; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology*; D015169:Colony Count, Microbial; D005260:Female; D006168:Guinea Pigs; D007074:Immunoglobulin G / Q000097:blood; D007371:Interferon-gamma / Q000378:metabolism; D018664:Interleukin-12 / Q000378:metabolism; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology; D017737:Macrophages, Peritoneal / Q000276:immunology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009169:Mycobacterium tuberculosis / Q000276:immunology; D009838:Oligodeoxyribonucleotides / Q000008:administration & dosage; D011993:Recombinant Fusion Proteins / Q000276:immunology; D013154:Spleen / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D014376:Tuberculosis / Q000517:prevention & control*; D032581:Tuberculosis Vaccines / Q000276:immunology*; D022223:Vaccines, Subunit / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C117940:CFP-10 protein, Mycobacterium tuberculosis; C408982:CPG-oligonucleotide; C093276:ESAT-6 protein, Mycobacterium tuberculosis; C118127:HspX protein, Mycobacterium tuberculosis; D007074:Immunoglobulin G; D009838:Oligodeoxyribonucleotides; D011993:Recombinant Fusion Proteins; D032581:Tuberculosis Vaccines; D022223:Vaccines, Subunit; D018664:Interleukin-12; D000536:Aluminum Hydroxide; D007371:Interferon-gamma; D000217:Acyltransferases; C121433:antigen 85B, Mycobacterium tuberculosis