title: Investigations into the binding affinities of different human 5-HT4 receptor splice variants.
authors.affiliation: Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Parkville, Vic., Australia. helen.irving@pharm.monash.edu.au
authors.forename: Helen R
authors.initials: HR
authors.lastname: Irving
authors.forename: Nathalie
authors.initials: N
authors.lastname: Tochon-Danguy
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Chinkwo
authors.forename: Jian G
authors.initials: JG
authors.lastname: Li
authors.forename: Carmen
authors.initials: C
authors.lastname: Grabbe
authors.forename: Marina
authors.initials: M
authors.lastname: Shapiro
authors.forename: Colin W
authors.initials: CW
authors.lastname: Pouton
authors.forename: Ian M
authors.initials: IM
authors.lastname: Coupar
mesh_terms: D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D001549:Benzamides / Q000378:metabolism; D001562:Benzimidazoles / Q000378:metabolism; D001572:Benzofurans / Q000378:metabolism; D001665:Binding Sites; D001667:Binding, Competitive; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000378:metabolism; D019556:COS Cells; D002522:Chlorocebus aethiops; D000242:Cyclic AMP / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007211:Indoles; D007700:Kinetics; D008024:Ligands; D010880:Piperidines / Q000378:metabolism; D020033:Protein Isoforms / Q000378:metabolism; D044422:Receptors, Serotonin, 5-HT4 / Q000235:genetics* / Q000378:metabolism; D058828:Serotonin 5-HT4 Receptor Agonists; D012702:Serotonin Antagonists / Q000378:metabolism
chemical_list: D000814:Aniline Compounds; D001549:Benzamides; D001562:Benzimidazoles; D001572:Benzofurans; D019086:Bridged Bicyclo Compounds, Heterocyclic; D007211:Indoles; D008024:Ligands; D010880:Piperidines; D020033:Protein Isoforms; D058828:Serotonin 5-HT4 Receptor Agonists; D012702:Serotonin Antagonists; C406662:prucalopride; C074331:DAU 6236; C070187:(endo-N-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1H-benzimidazol-1-carboxamide; D044422:Receptors, Serotonin, 5-HT4; C107826:RS 67333; C105050:tegaserod; C053006:renzapride; C055971:zacopride; D000242:Cyclic AMP