title: Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.
authors.affiliation: The Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.
authors.forename: Jens
authors.initials: J
authors.lastname: Ruschmann
authors.forename: Victor
authors.initials: V
authors.lastname: Ho
authors.forename: Frann
authors.initials: F
authors.lastname: Antignano
authors.forename: Etsushi
authors.initials: E
authors.lastname: Kuroda
authors.forename: Vivian
authors.initials: V
authors.lastname: Lam
authors.forename: Mariko
authors.initials: M
authors.lastname: Ibaraki
authors.forename: Kim
authors.initials: K
authors.lastname: Snyder
authors.forename: Connie
authors.initials: C
authors.lastname: Kim
authors.forename: Richard A
authors.initials: RA
authors.lastname: Flavell
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kawakami
authors.forename: Laura
authors.initials: L
authors.lastname: Sly
authors.forename: Ali G
authors.initials: AG
authors.lastname: Turhan
authors.forename: Gerald
authors.initials: G
authors.lastname: Krystal
mesh_terms: D000818:Animals; D002460:Cell Line / Q000378:metabolism; D003433:Crosses, Genetic; D015536:Down-Regulation; D004318:Doxycycline / Q000494:pharmacology; D016044:Fusion Proteins, bcr-abl / Q000502:physiology*; D006801:Humans; D000072181:Inositol Polyphosphate 5-Phosphatases; D007377:Interleukin-3 / Q000494:pharmacology; D015847:Interleukin-4 / Q000494:pharmacology; D008214:Lymphocytes / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D051059:PTEN Phosphohydrolase / Q000235:genetics / Q000378:metabolism; D000072183:Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D010766:Phosphorylation; D019000:Phosphotyrosine / Q000378:metabolism*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D011993:Recombinant Fusion Proteins / Q000502:physiology; D013047:Specific Pathogen-Free Organisms; D019061:src-Family Kinases / Q000172:deficiency / Q000502:physiology
chemical_list: D007377:Interleukin-3; D011993:Recombinant Fusion Proteins; D015847:Interleukin-4; D019000:Phosphotyrosine; D016044:Fusion Proteins, bcr-abl; D019061:src-Family Kinases; D010744:Phosphoric Monoester Hydrolases; D000072181:Inositol Polyphosphate 5-Phosphatases; D051059:PTEN Phosphohydrolase; C487757:Pten protein, mouse; C000606430:INPP5D protein, human; C000606433:Inpp5d protein, mouse; C000606435:Inppl1 protein, mouse; D000072183:Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; D046988:Proteasome Endopeptidase Complex; D004318:Doxycycline