Epitope mapping of function-blocking monoclonal antibody CM6 suggests a "weak" integrin binding site on the laminin-332 LG2 domain.
Yamashita
Hironobu
H
Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6840, USA.
Shang
Meiling
M
Tripathi
Manisha
M
Jourquin
Jerome
J
Georgescu
Walter
W
Liu
Shanshan
S
Weidow
Brandy
B
Quaranta
Vito
V
D000595:Amino Acid Sequence; D000818:Animals; D019138:Antibodies, Blocking / Q000378:metabolism*; D000911:Antibodies, Monoclonal / Q000378:metabolism*; D000918:Antibody Specificity; D001665:Binding Sites; D015815:Cell Adhesion Molecules / Q000737:chemistry* / Q000378:metabolism*; D002460:Cell Line; D002465:Cell Movement; D018604:Epitope Mapping; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D007797:Laminin / Q000378:metabolism; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010455:Peptides / Q000737:chemistry; D017434:Protein Structure, Tertiary; D051381:Rats; D000097794:Kalinin
D019138:Antibodies, Blocking; D000911:Antibodies, Monoclonal; D015815:Cell Adhesion Molecules; D016023:Integrins; D007797:Laminin; D010455:Peptides; D000097794:Kalinin; C095567:laminin alpha 3