The response to imatinib and interferon-alpha is more rapid than the response to imatinib alone: a retrospective analysis of 495 Philadelphia-positive chronic myeloid leukemia patients in early chronic phase.
Palandri
Francesca
F
Department of Hematology/Oncology L and A Seràgnoli, University of Bologna, S Orsola-Malpighi Hospital, Bologna, Italy. francesca.palandri@libero.it
Castagnetti
Fausto
F
Iacobucci
Ilaria
I
Martinelli
Giovanni
G
Amabile
Marilina
M
Gugliotta
Gabriele
G
Poerio
Angela
A
Testoni
Nicoletta
N
Breccia
Massimo
M
Bocchia
Monica
M
Crugnola
Monica
M
Rege-Cambrin
Giovanna
G
Martino
Bruno
B
Pierri
Ivana
I
Radaelli
Franca
F
Specchia
Giorgina
G
Pane
Fabrizio
F
Saglio
Giuseppe
G
Rosti
Gianantonio
G
Baccarani
Michele
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001549:Benzamides; D002986:Clinical Trials as Topic; D005260:Female; D016044:Fusion Proteins, bcr-abl / Q000235:genetics; D006801:Humans; D000068877:Imatinib Mesylate; D016898:Interferon-alpha / Q000008:administration & dosage; D053208:Kaplan-Meier Estimate; D015466:Leukemia, Myeloid, Chronic-Phase / Q000188:drug therapy* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use*; D011379:Prognosis; D047428:Protein Kinase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016896:Treatment Outcome; D055815:Young Adult
D001549:Benzamides; D016898:Interferon-alpha; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D016044:Fusion Proteins, bcr-abl