Pigment epithelium-derived factor inhibits erythropoietin-induced retinal endothelial cell angiogenesis by suppression of PI3K/Akt pathway.
Haribalaganesh
Ravinarayanan
R
Department of Biotechnology, Division of Molecular and Cellular biology, Kalasalingam University (Kalasalingam Academy of Research and Education), Anand Nagar, Krishnankoil 626190, Tamilnadu, India.
Sheikpranbabu
Sardarpasha
S
Banumathi
Elayappan
E
Gurunathan
Sangiliyandi
S
D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects; D018929:Cell Culture Techniques; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002867:Chromones / Q000494:pharmacology; D003911:Dextrans / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004797:Enzyme-Linked Immunosorbent Assay; D004921:Erythropoietin / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D005136:Eye Proteins / Q000494:pharmacology*; D006041:Goats; D009025:Morpholines / Q000494:pharmacology; D009414:Nerve Growth Factors / Q000494:pharmacology*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D000081082:Phosphoinositide-3 Kinase Inhibitors; D051057:Proto-Oncogene Proteins c-akt / Q000037:antagonists & inhibitors / Q000378:metabolism*; D015861:Retinal Neovascularization / Q000378:metabolism / Q000517:prevention & control*; D012171:Retinal Vessels / Q000166:cytology; D015843:Serpins / Q000494:pharmacology*; D014162:Transfection; D000099174:Pigment Epithelium-Derived Factor
D020533:Angiogenesis Inhibitors; D002867:Chromones; D003911:Dextrans; D004791:Enzyme Inhibitors; D004921:Erythropoietin; D005136:Eye Proteins; D009025:Morpholines; D009414:Nerve Growth Factors; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D051057:Proto-Oncogene Proteins c-akt; D015843:Serpins; D000099174:Pigment Epithelium-Derived Factor; C085911:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one