Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding.
Hagedorn
Ina
I
University Clinic, University of Würzburg, 97080 Würzburg, Germany.
Schmidbauer
Stefan
S
Pleines
Irina
I
Kleinschnitz
Christoph
C
Kronthaler
Ulrich
U
Stoll
Guido
G
Dickneite
Gerhard
G
Nieswandt
Bernhard
B
D000418:Albumins / Q000235:genetics / Q000494:pharmacology*; D000818:Animals; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000188:drug therapy*; D002545:Brain Ischemia / Q000097:blood / Q000188:drug therapy; D018076:DNA, Complementary; D015956:Factor XIIa / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000097:blood / Q000188:drug therapy*; D019476:Insect Proteins / Q000235:genetics / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D010314:Partial Thromboplastin Time; D051381:Rats; D011919:Rats, Inbred Strains; D011994:Recombinant Proteins / Q000235:genetics / Q000494:pharmacology; D013927:Thrombosis / Q000097:blood / Q000188:drug therapy*
D000418:Albumins; D018076:DNA, Complementary; D019476:Insect Proteins; D011994:Recombinant Proteins; C467902:infestin protein, Triatoma infestans; D015956:Factor XIIa