Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline.
Comi
Cristoforo
C
Interdisciplinary Research Center of Autoimmune Diseases, A Avogadro University of Eastern Piedmont, Novara, Italy. comi@med.unipmn.it
Carecchio
Miryam
M
Chiocchetti
Annalisa
A
Nicola
Stefania
S
Galimberti
Daniela
D
Fenoglio
Chiara
C
Cappellano
Giuseppe
G
Monaco
Francesco
F
Scarpini
Elio
E
Dianzani
Umberto
U
D000368:Aged; D000544:Alzheimer Disease / Q000134:cerebrospinal fluid* / Q000453:epidemiology* / Q000473:pathology; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017628:Microglia / Q000000981:diagnostic imaging / Q000473:pathology; D009410:Nerve Degeneration / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000473:pathology; D009483:Neuropsychological Tests; D053495:Osteopontin / Q000134:cerebrospinal fluid*; D049268:Positron-Emission Tomography; D012720:Severity of Illness Index; D016875:tau Proteins / Q000134:cerebrospinal fluid
D016875:tau Proteins; D053495:Osteopontin