SNP improves cerebral hemodynamics during normotension but fails to prevent sex dependent impaired cerebral autoregulation during hypotension after brain injury.
Armstead
William M
WM
Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA. armsteaw@uphs.upenn.edu
Kiessling
J Willis
JW
Kofke
W Andrew
WA
Vavilala
Monica S
MS
D000818:Animals; D000831:Animals, Newborn; D001158:Arteries / Q000187:drug effects / Q000503:physiopathology; D001921:Brain / Q000098:blood supply / Q000187:drug effects* / Q000503:physiopathology; D001930:Brain Injuries / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D002317:Cardiovascular Agents / Q000494:pharmacology*; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology; D048049:Extracellular Signal-Regulated MAP Kinases / Q000134:cerebrospinal fluid / Q000378:metabolism; D005260:Female; D019585:Intracranial Hypotension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D020935:MAP Kinase Signaling System / Q000187:drug effects; D008297:Male; D009599:Nitroprusside / Q000494:pharmacology*; D010841:Pia Mater / Q000098:blood supply / Q000187:drug effects / Q000503:physiopathology; D012727:Sex Characteristics; D013552:Swine; D013997:Time Factors
D002317:Cardiovascular Agents; D009599:Nitroprusside; D048049:Extracellular Signal-Regulated MAP Kinases