Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart.
Gardier
Stephany
S
Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. stephany.gardier@hcuge.ch
Pedretti
Sarah
S
Sarre
Alexandre
A
Raddatz
Eric
E
D000818:Animals; D002642:Chick Embryo; D003981:Diazoxide / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism; D006321:Heart / Q000187:drug effects / Q000196:embryology*; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D000860:Hypoxia / Q000196:embryology / Q000201:enzymology*; D048031:JNK Mitogen-Activated Protein Kinases / Q000378:metabolism; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D009206:Myocardium / Q000201:enzymology*; D018384:Oxidative Stress / Q000187:drug effects*; D010766:Phosphorylation; D015221:Potassium Channels / Q000819:agonists / Q000378:metabolism; D013997:Time Factors; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism
D015221:Potassium Channels; C117780:mitochondrial K(ATP) channel; D006861:Hydrogen Peroxide; D048049:Extracellular Signal-Regulated MAP Kinases; D048031:JNK Mitogen-Activated Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D003981:Diazoxide