Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response.
Heo
Muyoung
M
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Shakhnovich
Eugene I
EI
D000222:Adaptation, Physiological / Q000235:genetics; D000818:Animals; D020137:Base Pair Mismatch / Q000235:genetics*; D003198:Computer Simulation; D005828:Genetics, Population; D006801:Humans; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics*; D012641:Selection, Genetic / Q000235:genetics*; D013312:Stress, Physiological / Q000235:genetics*