title: Lepidopteran-active variable-region sequence imparts coleopteran activity in eCry3.1Ab, an engineered Bacillus thuringiensis hybrid insecticidal protein.
authors.affiliation: Syngenta Biotechnology, Inc., Durham, NC 27709-2257, USA. Frederick.Walters@Syngenta.com
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Walters
authors.forename: Cheryl M
authors.initials: CM
authors.lastname: deFontes
authors.forename: Hope
authors.initials: H
authors.lastname: Hart
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Warren
authors.forename: Jeng S
authors.initials: JS
authors.lastname: Chen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001413:Bacillus thuringiensis / Q000235:genetics* / Q000378:metabolism; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000378:metabolism / Q000494:pharmacology*; D002918:Chymotrypsin / Q000378:metabolism; D001517:Coleoptera / Q000187:drug effects* / Q000235:genetics; D004731:Endotoxins / Q000378:metabolism / Q000494:pharmacology*; D006460:Hemolysin Proteins / Q000378:metabolism / Q000494:pharmacology*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D008871:Microvilli / Q000187:drug effects; D011485:Protein Binding / Q000187:drug effects; D011993:Recombinant Fusion Proteins / Q000494:pharmacology*; D016415:Sequence Alignment
chemical_list: D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D004731:Endotoxins; D006460:Hemolysin Proteins; D007306:Insecticides; D011993:Recombinant Fusion Proteins; C030956:insecticidal crystal protein, Bacillus Thuringiensis; D002918:Chymotrypsin