Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera.
Sartorelli
Patrícia
P
Departamento de Ciências Exatas e da Terra, Universidade Federal de São Paulo, Diadema/São Paulo, Brazil. psartorelli@unifesp.br
Carvalho
Camila Salomone
CS
Reimão
Juliana Quero
JQ
Lorenzi
Harri
H
Tempone
André Gustavo
AG
D000818:Animals; D030022:Aristolochia / Q000737:chemistry*; D014355:Chagas Disease / Q000188:drug therapy*; D004224:Diterpenes / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D053878:Hemolytic Agents / Q000009:adverse effects; D020128:Inhibitory Concentration 50; D017705:Lignans / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D018515:Plant Leaves; D014344:Trypanocidal Agents / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D014349:Trypanosoma cruzi / Q000187:drug effects*
D004224:Diterpenes; D053878:Hemolytic Agents; D017705:Lignans; D010936:Plant Extracts; D014344:Trypanocidal Agents; C556511:copalic acid; C556512:kusunokinin