2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells.
Sánchez-Martín
Francisco J
FJ
Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain.
Fernández-Salguero
Pedro M
PM
Merino
Jaime M
JM
D000704:Analysis of Variance; D000818:Animals; D017304:Annexin A5 / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects*; D053148:Caspase 3 / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004147:Dioxins / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005434:Flow Cytometry / Q000379:methods; D005786:Gene Expression Regulation / Q000187:drug effects; D006624:Hippocampus / Q000166:cytology; D007211:Indoles; D020932:Nerve Growth Factor / Q000494:pharmacology*; D009457:Neuroglia / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D009498:Neurotoxins / Q000633:toxicity*; D016716:PC12 Cells / Q000187:drug effects; D051381:Rats; D017382:Reactive Oxygen Species / Q000378:metabolism
D017304:Annexin A5; D004147:Dioxins; D007211:Indoles; D009498:Neurotoxins; D017382:Reactive Oxygen Species; C066841:2,3,7,8-tetrabromodibenzo-4-dioxin; C007293:DAPI; D020932:Nerve Growth Factor; D053148:Caspase 3