Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression.
Tree
Timothy I M
TI
Department of Immunobiology, King's College London, Guy's Hospital, London, UK. timothy.tree@kcl.ac.uk
Lawson
Jennifer
J
Edwards
Hannah
H
Skowera
Ania
A
Arif
Sefina
S
Roep
Bart O
BO
Peakman
Mark
M
D001324:Autoantigens / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D002470:Cell Survival; D016207:Cytokines / Q000235:genetics / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy; D016753:Interleukin-10 / Q000378:metabolism*; D007515:Islets of Langerhans / Q000276:immunology*; D012016:Reference Values; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000166:cytology / Q000276:immunology*
D001324:Autoantigens; D016207:Cytokines; D016753:Interleukin-10