Polymeric micelles as a drug delivery system enhance cytotoxicity of vinorelbine through more intercellular accumulation.
Lu
Xiaoyan
X
Protein & Peptide Pharmaceutical Laboratory, Institute of Biophysics, Chinese Academy of Sciences, PR China.
Zhang
Fayun
F
Qin
Lei
L
Xiao
Fengying
F
Liang
Wei
W
D000818:Animals; D016923:Cell Death / Q000187:drug effects / Q000502:physiology; D045744:Cell Line, Tumor; D003603:Cytotoxins / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D016503:Drug Delivery Systems / Q000379:methods*; D045604:Extracellular Fluid / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D008823:Micelles; D011108:Polymers / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D014747:Vinblastine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000633:toxicity; D000077235:Vinorelbine
D003603:Cytotoxins; D008823:Micelles; D011108:Polymers; D014747:Vinblastine; D000077235:Vinorelbine