title: Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function.
authors.affiliation: Centre for Sustainable Pest and Disease Management, Department of Plant Pathology and Microbiology, Rothamsted Research, Hertfordshire, United Kingdom. hans.cools@bbsrc.ac.uk
authors.forename: H J
authors.initials: HJ
authors.lastname: Cools
authors.forename: J E
authors.initials: JE
authors.lastname: Parker
authors.forename: D E
authors.initials: DE
authors.lastname: Kelly
authors.forename: J A
authors.initials: JA
authors.lastname: Lucas
authors.forename: B A
authors.initials: BA
authors.lastname: Fraaije
authors.forename: S L
authors.initials: SL
authors.lastname: Kelly
mesh_terms: D001203:Ascomycota / Q000201:enzymology* / Q000235:genetics; D001393:Azoles / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D005659:Fungicides, Industrial / Q000494:pharmacology*; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D058886:Sterol 14-Demethylase; D013261:Sterols / Q000096:biosynthesis; D014908:Triticum / Q000382:microbiology
chemical_list: D001393:Azoles; D005659:Fungicides, Industrial; D013261:Sterols; D003577:Cytochrome P-450 Enzyme System; D058886:Sterol 14-Demethylase