IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis.
Cao
Qi
Q
Centre for Transplantation and Renal Research, University of Sydney, Westmead Millennium Institute, and Centre for Kidney Research, Children's Hospital at Westmead, Level 2 Block D, Darcy Road, Westmead, New South Wales, Australia.
Wang
Yiping
Y
Zheng
Dong
D
Sun
Yan
Y
Wang
Ya
Y
Lee
Vincent W S
VW
Zheng
Guoping
G
Tan
Thian Kui
TK
Ince
Jon
J
Alexander
Stephen I
SI
Harris
David C H
DC
D000818:Animals; D018122:B7-1 Antigen / Q000378:metabolism; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D004195:Disease Models, Animal; D004317:Doxorubicin / Q000009:adverse effects; D016753:Interleukin-10 / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008264:Macrophages / Q000187:drug effects* / Q000473:pathology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009401:Nephrosis / Q000139:chemically induced / Q000503:physiopathology* / Q000517:prevention & control*; D052247:Nitric Oxide Synthase Type II / Q000378:metabolism; D010641:Phenotype; D050378:T-Lymphocytes, Regulatory / Q000473:pathology*; D016212:Transforming Growth Factor beta / Q000494:pharmacology*; D060907:V-Set Domain-Containing T-Cell Activation Inhibitor 1
D018122:B7-1 Antigen; D016212:Transforming Growth Factor beta; D060907:V-Set Domain-Containing T-Cell Activation Inhibitor 1; C475826:VTCN1 protein, human; D016753:Interleukin-10; D004317:Doxorubicin; D052247:Nitric Oxide Synthase Type II