A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice.
Sato
Hajime
H
Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Suzuki
Tomohiro
T
Ikeda
Kyoko
K
Masuya
Hiroshi
H
Sezutsu
Hideki
H
Kaneda
Hideki
H
Kobayashi
Kimio
K
Miura
Ikuo
I
Kurihara
Yasuyuki
Y
Yokokura
Shunji
S
Nishida
Kohji
K
Tamai
Makoto
M
Gondo
Yoichi
Y
Noda
Tetsuo
T
Wakana
Shigeharu
S
D000818:Animals; D001483:Base Sequence; D004252:DNA Mutational Analysis; D004596:Electroretinography; D005038:Ethylnitrosourea; D005136:Eye Proteins / Q000235:genetics* / Q000378:metabolism; D005654:Fundus Oculi; D005786:Gene Expression Regulation; D005799:Genes, Dominant / Q000235:genetics*; D006239:Haplotypes / Q000235:genetics; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000235:genetics / Q000378:metabolism; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D008969:Molecular Sequence Data; D016296:Mutagenesis; D009154:Mutation / Q000235:genetics*; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D064531:Peripherins; D010641:Phenotype; D020419:Photoreceptor Cells, Vertebrate / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure; D012162:Retinal Degeneration / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D059470:Tetraspanins
D005136:Eye Proteins; D007381:Intermediate Filament Proteins; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D064531:Peripherins; C578996:Prph2 protein, mouse; C081477:Rom1 protein, mouse; D059470:Tetraspanins; D005038:Ethylnitrosourea