Serotonin signaling is altered in irritable bowel syndrome with diarrhea but not in functional dyspepsia in pediatric age patients.
Faure
Christophe
C
Division of Gastroenterology, Department of Pediatrics, Centre Hospitalier Universitaire Ste-Justine, Montréal, Quebec, Canada. christophe.faure@umontreal.ca
Patey
Natalie
N
Gauthier
Cindy
C
Brooks
Elice M
EM
Mawe
Gary M
GM
D000293:Adolescent; D002648:Child; D003967:Diarrhea / Q000378:metabolism*; D004415:Dyspepsia / Q000378:metabolism*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000378:metabolism*; D008297:Male; D050811:Octamer Transcription Factor-1 / Q000235:genetics; D012333:RNA, Messenger / Q000032:analysis; D012701:Serotonin / Q000032:analysis / Q000235:genetics / Q000502:physiology*; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics; D015398:Signal Transduction / Q000502:physiology*; D014365:Tryptophan Hydroxylase / Q000235:genetics
D050811:Octamer Transcription Factor-1; D012333:RNA, Messenger; D050486:Serotonin Plasma Membrane Transport Proteins; D012701:Serotonin; C497467:TPH1 protein, human; D014365:Tryptophan Hydroxylase