title: 4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: first boronic acid-derived beta-lactamase inhibitor with class A, C, and D activity.
authors.affiliation: Department of Medicinal Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA. qiang_tan@merck.com
authors.forename: Qiang
authors.initials: Q
authors.lastname: Tan
authors.forename: Aimie M
authors.initials: AM
authors.lastname: Ogawa
authors.forename: Ronald E
authors.initials: RE
authors.lastname: Painter
authors.forename: Young-Whan
authors.initials: YW
authors.lastname: Park
authors.forename: Katherine
authors.initials: K
authors.lastname: Young
authors.forename: Frank P
authors.initials: FP
authors.lastname: DiNinno
mesh_terms: D040981:Acinetobacter baumannii / Q000187:drug effects; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001897:Boronic Acids / Q000737:chemistry / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D020128:Inhibitory Concentration 50; D008826:Microbial Sensitivity Tests; D065093:beta-Lactamase Inhibitors
chemical_list: D000900:Anti-Bacterial Agents; D001897:Boronic Acids; D004791:Enzyme Inhibitors; D065093:beta-Lactamase Inhibitors