title: Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.
authors.affiliation: Departments of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, USA.
authors.forename: Risheng
authors.initials: R
authors.lastname: Cao
authors.forename: Zhumei Xu
authors.initials: ZX
authors.lastname: Cronk
authors.forename: Weibin
authors.initials: W
authors.lastname: Zha
authors.forename: Lixin
authors.initials: L
authors.lastname: Sun
authors.forename: Xuan
authors.initials: X
authors.lastname: Wang
authors.forename: Youwen
authors.initials: Y
authors.lastname: Fang
authors.forename: Elaine
authors.initials: E
authors.lastname: Studer
authors.forename: Huiping
authors.initials: H
authors.lastname: Zhou
authors.forename: William M
authors.initials: WM
authors.lastname: Pandak
authors.forename: Paul
authors.initials: P
authors.lastname: Dent
authors.forename: Gregorio
authors.initials: G
authors.lastname: Gil
authors.forename: Phillip B
authors.initials: PB
authors.lastname: Hylemon
mesh_terms: D000818:Animals; D002262:Carboxy-Lyases / Q000235:genetics; D015536:Down-Regulation / Q000187:drug effects; D005402:Fistula / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D005943:Gluconeogenesis / Q000187:drug effects / Q000235:genetics*; D005952:Glucose-6-Phosphatase / Q000235:genetics; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism; D007328:Insulin / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism* / Q000473:pathology; D008297:Male; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D000081382:Pyruvate Dehydrogenase Acetyl-Transferring Kinase; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D013656:Taurocholic Acid / Q000494:pharmacology*; D000099150:Receptor, Farnesoid X-Activated
chemical_list: D002262:Carboxy-Lyases; D005952:Glucose-6-Phosphatase; D007328:Insulin; D019869:Phosphatidylinositol 3-Kinases; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D000081382:Pyruvate Dehydrogenase Acetyl-Transferring Kinase; D012333:RNA, Messenger; D018160:Receptors, Cytoplasmic and Nuclear; D043562:Receptors, G-Protein-Coupled; D013656:Taurocholic Acid; D000099150:Receptor, Farnesoid X-Activated; C099713:nuclear receptor subfamily 0, group B, member 2