Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator.
Jin
Rong
R
Department of Neurosurgery, LSU Health Science Center, Shreveport, LA 71130, USA.
Yang
Guojun
G
Li
Guohong
G
D000818:Animals; D018916:Blood-Aqueous Barrier / Q000378:metabolism*; D002545:Brain Ischemia / Q000378:metabolism*; D002199:Capillary Permeability / Q000502:physiology; D006801:Humans; D020782:Matrix Metalloproteinases / Q000378:metabolism*; D015398:Signal Transduction; D020521:Stroke / Q000378:metabolism*; D010959:Tissue Plasminogen Activator / Q000378:metabolism*
D010959:Tissue Plasminogen Activator; D020782:Matrix Metalloproteinases