title: Rho kinase inhibitor fasudil suppresses migration and invasion though down-regulating the expression of VEGF in lung cancer cell line A549.
authors.affiliation: Department of Oncology, The Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Zhu
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.forename: Gang
authors.initials: G
authors.lastname: Wu
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Li
authors.forename: Ruiguang
authors.initials: R
authors.lastname: Zhang
authors.forename: Jinghua
authors.initials: J
authors.lastname: Ren
authors.forename: Li
authors.initials: L
authors.lastname: Nong
mesh_terms: D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology*; D015153:Blotting, Western; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects; D015536:Down-Regulation; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology; D009361:Neoplasm Invasiveness; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D042461:Vascular Endothelial Growth Factor A / Q000096:biosynthesis*; D054460:rho-Associated Kinases / Q000037:antagonists & inhibitors / Q000096:biosynthesis
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D054460:rho-Associated Kinases; C049347:fasudil