Cytokine antagonism reduces pain and modulates spinal astrocytic reactivity after cervical nerve root compression.
Rothman
Sarah M
SM
Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 S. 33rd Street, Philadelphia, PA 19104-6321, USA.
Winkelstein
Beth A
BA
D000818:Animals; D001253:Astrocytes / Q000378:metabolism*; D016207:Cytokines / Q000037:antagonists & inhibitors*; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D053583:Interleukin-1beta / Q000378:metabolism; D008297:Male; D019838:Neck Injuries / Q000503:physiopathology; D009457:Neuroglia / Q000378:metabolism; D010146:Pain / Q000503:physiopathology*; D011843:Radiculopathy / Q000503:physiopathology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013117:Spinal Cord Compression / Q000503:physiopathology; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D016207:Cytokines; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D053583:Interleukin-1beta; D014409:Tumor Necrosis Factor-alpha