Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells.
Adigun
Abayomi A
AA
Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.
Ryde
Ian T
IT
Seidler
Frederic J
FJ
Slotkin
Theodore A
TA
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D004390:Chlorpyrifos / Q000633:toxicity; D002800:Cholinesterase Inhibitors / Q000633:toxicity; D003976:Diazinon / Q000633:toxicity; D007306:Insecticides / Q000633:toxicity; D009474:Neurons / Q000187:drug effects* / Q000201:enzymology; D010755:Organophosphates / Q000633:toxicity*; D016716:PC12 Cells; D010278:Parathion / Q000633:toxicity; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects*; D013997:Time Factors
D002800:Cholinesterase Inhibitors; D007306:Insecticides; D010755:Organophosphates; D010278:Parathion; D000262:Adenylyl Cyclases; D004390:Chlorpyrifos; D003976:Diazinon