Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound.
Chatterjee
Sudipa June
SJ
aDepartment of Chemistry and Biochemistry, University of Windsor, Windsor bDepartment of Chemistry, McMaster University, Hamilton, Ontario, Canada.
McNulty
James
J
Pandey
Siyaram
S
D047151:Amaryllidaceae Alkaloids / Q000008:administration & dosage*; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D017209:Apoptosis; D053148:Caspase 3 / Q000378:metabolism; D045744:Cell Line, Tumor; D004260:DNA Repair; D019008:Drug Resistance, Neoplasm; D004357:Drug Synergism; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007546:Isoquinolines / Q000008:administration & dosage*; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology*; D053078:Membrane Potential, Mitochondrial; D017382:Reactive Oxygen Species / Q000378:metabolism; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*; D013629:Tamoxifen / Q000008:administration & dosage*
D047151:Amaryllidaceae Alkaloids; D018931:Antineoplastic Agents, Hormonal; D007546:Isoquinolines; D017382:Reactive Oxygen Species; D013629:Tamoxifen; C044997:pancratistatin; C505407:CASP3 protein, human; D053148:Caspase 3