Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.
Albaugh
V L
VL
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Judson
J G
JG
She
P
P
Lang
C H
CH
Maresca
K P
KP
Joyal
J L
JL
Lynch
C J
CJ
D000273:Adipose Tissue / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D001569:Benzodiazepines / Q000008:administration & dosage*; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition / Q000187:drug effects; D004734:Energy Metabolism / Q000187:drug effects*; D005947:Glucose / Q000378:metabolism; D015309:Glucose Clamp Technique; D050155:Lipogenesis / Q000187:drug effects*; D008066:Lipolysis / Q000187:drug effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D000077152:Olanzapine; D051381:Rats; D017207:Rats, Sprague-Dawley; D012646:Self Administration; D013997:Time Factors
D014150:Antipsychotic Agents; D001786:Blood Glucose; D001569:Benzodiazepines; D005947:Glucose; D000077152:Olanzapine