title: Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.
authors.affiliation: Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02138, USA.
authors.forename: Dragony
authors.initials: D
authors.lastname: Fu
authors.forename: Jennifer A N
authors.initials: JA
authors.lastname: Brophy
authors.forename: Clement T Y
authors.initials: CT
authors.lastname: Chan
authors.forename: Kyle A
authors.initials: KA
authors.lastname: Atmore
authors.forename: Ulrike
authors.initials: U
authors.lastname: Begley
authors.forename: Richard S
authors.initials: RS
authors.lastname: Paules
authors.forename: Peter C
authors.initials: PC
authors.lastname: Dedon
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Begley
authors.forename: Leona D
authors.initials: LD
authors.lastname: Samson
mesh_terms: D000071503:AlkB Homolog 8, tRNA Methyltransferase; D000818:Animals; D002460:Cell Line; D004249:DNA Damage; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012343:RNA, Transfer / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D014529:Uridine / Q000737:chemistry / Q000378:metabolism*; D012359:tRNA Methyltransferases / Q000145:classification / Q000235:genetics / Q000378:metabolism*
chemical_list: D012343:RNA, Transfer; C549623:ALKBH8 protein, human; D000071503:AlkB Homolog 8, tRNA Methyltransferase; D012359:tRNA Methyltransferases; D014529:Uridine