Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss.
Spieles-Engemann
A L
AL
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267, USA.
Behbehani
M M
MM
Collier
T J
TJ
Wohlgenant
S L
SL
Steece-Collier
K
K
Paumier
K
K
Daley
B F
BF
Gombash
S
S
Madhavan
L
L
Mandybur
G T
GT
Lipton
J W
JW
Terpstra
B T
BT
Sortwell
C E
CE
D000818:Animals; D016923:Cell Death / Q000502:physiology; D019610:Cytoprotection / Q000502:physiology*; D046690:Deep Brain Stimulation / Q000379:methods*; D004195:Disease Models, Animal; D004298:Dopamine / Q000096:biosynthesis*; D008297:Male; D009410:Nerve Degeneration / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control*; D009433:Neural Inhibition / Q000502:physiology; D020734:Parkinsonian Disorders / Q000473:pathology / Q000628:therapy*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013378:Substantia Nigra / Q000378:metabolism / Q000473:pathology*; D020531:Subthalamic Nucleus / Q000378:metabolism / Q000473:pathology / Q000502:physiology*; D016896:Treatment Outcome
D004298:Dopamine