title: Calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions.
authors.affiliation: Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota 55455, USA.
authors.forename: Prakash
authors.initials: P
authors.lastname: Sundaramurthi
authors.forename: Evgenyi
authors.initials: E
authors.lastname: Shalaev
authors.forename: Raj
authors.initials: R
authors.lastname: Suryanarayanan
mesh_terms: D002021:Buffers; D002152:Calorimetry, Differential Scanning; D003080:Cold Temperature; D003460:Crystallization; D006863:Hydrogen-Ion Concentration; D012996:Solutions; D019802:Succinic Acid / Q000737:chemistry*; D017356:Synchrotrons; D014961:X-Ray Diffraction
chemical_list: D002021:Buffers; D012996:Solutions; D019802:Succinic Acid