Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs.
Penaranda
Cristina
C
Diabetes Center and Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Tang
Qizhi
Q
Ruddle
Nancy H
NH
Bluestone
Jeffrey A
JA
D000293:Adolescent; D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D002648:Child; D004268:DNA-Binding Proteins / Q000172:deficiency; D003920:Diabetes Mellitus / Q000517:prevention & control*; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology; D000068876:Fingolimod Hydrochloride; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007515:Islets of Langerhans / Q000276:immunology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D051379:Mice; D016688:Mice, Inbred NOD; D018345:Mice, Knockout; D011409:Propylene Glycols / Q000627:therapeutic use*; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000502:physiology / Q000627:therapeutic use; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D055815:Young Adult
D004268:DNA-Binding Proteins; D007166:Immunosuppressive Agents; D011409:Propylene Glycols; C499308:Rag2 protein, mouse; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine