title: Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma.
authors.affiliation: Department of Medical Oncology and Hematology, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada. donna.reece@uhn.on.ca
authors.forename: Donna E
authors.initials: DE
authors.lastname: Reece
authors.forename: Dan
authors.initials: D
authors.lastname: Sullivan
authors.forename: Sagar
authors.initials: S
authors.lastname: Lonial
authors.forename: Ann F
authors.initials: AF
authors.lastname: Mohrbacher
authors.forename: Gurkamal
authors.initials: G
authors.lastname: Chatta
authors.forename: Chaim
authors.initials: C
authors.lastname: Shustik
authors.forename: Howard
authors.initials: H
authors.lastname: Burris
authors.forename: Karthik
authors.initials: K
authors.lastname: Venkatakrishnan
authors.forename: Rachel
authors.initials: R
authors.lastname: Neuwirth
authors.forename: William J
authors.initials: WJ
authors.lastname: Riordan
authors.forename: Michael
authors.initials: M
authors.lastname: Karol
authors.forename: Lisa L
authors.initials: LL
authors.lastname: von Moltke
authors.forename: Milin
authors.initials: M
authors.lastname: Acharya
authors.forename: Peter
authors.initials: P
authors.lastname: Zannikos
authors.forename: A
authors.initials: A
authors.lastname: Keith Stewart
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D001897:Boronic Acids / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D000069286:Bortezomib; D004305:Dose-Response Relationship, Drug; D005260:Female; D006207:Half-Life; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy*; D011446:Prospective Studies; D011480:Protease Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D061988:Proteasome Inhibitors; D011719:Pyrazines / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D001897:Boronic Acids; D011480:Protease Inhibitors; D061988:Proteasome Inhibitors; D011719:Pyrazines; D000069286:Bortezomib