Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells.
Zhang
Yinghui
Y
Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, Guangdong, China.
Lian
Fuzhi
F
Zhu
Yanna
Y
Xia
Min
M
Wang
Qing
Q
Ling
Wenhua
W
Wang
Xiang-Dong
XD
D000872:Anthocyanins / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002460:Cell Line; D004305:Dose-Response Relationship, Drug; D015870:Gene Expression / Q000187:drug effects; D005960:Glucosides / Q000494:pharmacology*; D006801:Humans; D020672:I-kappa B Proteins / Q000032:analysis / Q000378:metabolism*; D018836:Inflammation Mediators / Q000037:antagonists & inhibitors* / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D008070:Lipopolysaccharides / Q000633:toxicity; D008264:Macrophages / Q000187:drug effects*; D016328:NF-kappa B / Q000378:metabolism; D009570:Nitriles / Q000494:pharmacology; D010766:Phosphorylation / Q000187:drug effects; D013450:Sulfones / Q000494:pharmacology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000378:metabolism; D000093242:Interleukin-6 Inhibitors
D000872:Anthocyanins; D000893:Anti-Inflammatory Agents; D005960:Glucosides; D020672:I-kappa B Proteins; D018836:Inflammation Mediators; D015850:Interleukin-6; D008070:Lipopolysaccharides; D016328:NF-kappa B; D009570:Nitriles; D013450:Sulfones; D014409:Tumor Necrosis Factor-alpha; D000093242:Interleukin-6 Inhibitors; C434003:3-(4-methylphenylsulfonyl)-2-propenenitrile; C462279:cyanidin-3-O-beta-glucopyranoside