Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma.
Morton
Jennifer P
JP
Beatson Institute for Cancer Research, Glasgow, United Kingdom.
Karim
Saadia A
SA
Graham
Kathryn
K
Timpson
Paul
P
Jamieson
Nigel
N
Athineos
Dimitris
D
Doyle
Brendan
B
McKay
Colin
C
Heung
Man-Yeung
MY
Oien
Karin A
KA
Frame
Margaret C
MC
Evans
T R Jeffry
TR
Sansom
Owen J
OJ
Brunton
Valerie G
VG
D000818:Animals; D021441:Carcinoma, Pancreatic Ductal / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects; D000069439:Dasatinib; D004195:Disease Models, Animal; D005260:Female; D051379:Mice; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D013844:Thiazoles / Q000627:therapeutic use*; D019061:src-Family Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism
D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D013844:Thiazoles; D019061:src-Family Kinases; D000069439:Dasatinib