MDR1 C2005T polymorphism changes substrate specificity.
Liu
Lijuan
L
Institute of Clinical Pharmacology, Central South University, Changsha, China.
Fan
Lan
L
Peng
Xiangdong
X
Hu
Dongli
D
Zhou
Honghao
H
D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics*; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001692:Biological Transport; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D004351:Drug Resistance; D004847:Epithelial Cells / Q000378:metabolism; D020128:Inhibitory Concentration 50; D018613:Microscopy, Confocal; D010539:Permeability; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012333:RNA, Messenger / Q000378:metabolism; D020112:Rhodamine 123 / Q000493:pharmacokinetics; D013379:Substrate Specificity; D013552:Swine; D014162:Transfection
C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000970:Antineoplastic Agents; D012333:RNA, Messenger; D020112:Rhodamine 123