Tumor necrosis factor-{alpha} rs361525 polymorphism is associated with increased local production and downstream inflammation in chronic obstructive pulmonary disease.
Sapey
Elizabeth
E
Department of Clinical and Experimental Medicine, University of Birmingham Edgbaston, Birmingham, UK B15 2TT. lizsapey@aol.com
Wood
Alice M
AM
Ahmad
Ali
A
Stockley
Robert A
RA
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D001980:Bronchi / Q000166:cytology; D001991:Bronchitis / Q000453:epidemiology; D016022:Case-Control Studies; D002465:Cell Movement; D018450:Disease Progression; D004847:Epithelial Cells / Q000378:metabolism; D005260:Female; D005541:Forced Expiratory Volume; D005838:Genotype; D006801:Humans; D016209:Interleukin-8 / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000502:physiology; D009195:Peroxidase / Q000378:metabolism; D010641:Phenotype; D011110:Polymorphism, Genetic; D029424:Pulmonary Disease, Chronic Obstructive / Q000235:genetics*; D012720:Severity of Illness Index; D013183:Sputum / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics* / Q000378:metabolism
D016209:Interleukin-8; D014409:Tumor Necrosis Factor-alpha; D009195:Peroxidase