MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.
Miller
Jordan D
JD
Division of Cardiovascular Surgery and Department of Physiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA. miller.jordan@mayo.edu
Peotta
Veronica A
VA
Chu
Yi
Y
Weiss
Robert M
RM
Zimmerman
Kathy
K
Brooks
Robert M
RM
Heistad
Donald D
DD
D000818:Animals; D030801:Animals, Genetically Modified; D002908:Chronic Disease; D003331:Coronary Vessels / Q000502:physiology; D051545:Cyclooxygenase 1 / Q000235:genetics / Q000502:physiology*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology*; D018628:Gene Dosage; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006334:Heart Function Tests; D007527:Isoenzymes / Q000235:genetics / Q000502:physiology; D008026:Ligation; D051379:Mice; D008810:Mice, Inbred C57BL; D008931:Mitochondria, Muscle / Q000378:metabolism; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000473:pathology; D009569:Nitric Oxide / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013482:Superoxide Dismutase / Q000235:genetics* / Q000502:physiology*; D013481:Superoxides / Q000378:metabolism; D016277:Ventricular Function, Left
D007527:Isoenzymes; D013481:Superoxides; D009569:Nitric Oxide; D051545:Cyclooxygenase 1; D013482:Superoxide Dismutase