title: Dominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidy.
authors.affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
authors.forename: Vibhor
authors.initials: V
authors.lastname: Gupta
authors.forename: Ponnusamy
authors.initials: P
authors.lastname: Kalaiarasan
authors.forename: Mohammad
authors.initials: M
authors.lastname: Faheem
authors.forename: Nishant
authors.initials: N
authors.lastname: Singh
authors.forename: Mohammad Askandar
authors.initials: MA
authors.lastname: Iqbal
authors.forename: Rameshwar N K
authors.initials: RN
authors.lastname: Bamezai
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D018450:Disease Progression; D004926:Escherichia coli / Q000378:metabolism; D005434:Flow Cytometry; D005799:Genes, Dominant; D005982:Glutathione Transferase / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D007527:Isoenzymes / Q000737:chemistry; D007700:Kinetics; D009154:Mutation; D011123:Polyploidy; D011770:Pyruvate Kinase / Q000737:chemistry*; D020798:Two-Hybrid System Techniques
chemical_list: D007527:Isoenzymes; D005982:Glutathione Transferase; D011770:Pyruvate Kinase