Potential use of gamma-cyclodextrin polypseudorotaxane hydrogels as an injectable sustained release system for insulin.
Abu Hashim
Irhan Ibrahim
II
Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Higashi
Taishi
T
Anno
Takayuki
T
Motoyama
Keiichi
K
Abd-ElGawad
Abd-ElGawad Helmy
AE
El-Shabouri
Mohamed H
MH
Borg
Thanaa Mohamed
TM
Arima
Hidetoshi
H
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002152:Calorimetry, Differential Scanning; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry*; D020100:Hydrogels; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics; D007279:Injections, Subcutaneous; D007328:Insulin / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008855:Microscopy, Electron, Scanning; D051381:Rats; D017208:Rats, Wistar; D043862:Rotaxanes / Q000737:chemistry*; D012995:Solubility; D013499:Surface Properties; D014961:X-Ray Diffraction; D047408:gamma-Cyclodextrins / Q000737:chemistry*
D001786:Blood Glucose; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D020100:Hydrogels; D007004:Hypoglycemic Agents; D007328:Insulin; D043862:Rotaxanes; D047408:gamma-Cyclodextrins