Granular insular cortex inactivation as a novel therapeutic strategy for nicotine addiction.
Forget
Benoit
B
Translational Addiction Research Laboratory, Pharmacology and Psychiatry, Institutes of Medical Sciences, University of Toronto, Toronto, Canada.
Pushparaj
Abhiram
A
Le Foll
Bernard
B
D000704:Analysis of Variance; D000818:Animals; D001245:Association Learning / Q000187:drug effects; D001418:Baclofen / Q000008:administration & dosage; D016739:Behavior, Addictive / Q000517:prevention & control*; D001522:Behavior, Animal / Q000187:drug effects; D002540:Cerebral Cortex / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects; D004195:Disease Models, Animal; D004338:Drug Combinations; D005108:Extinction, Psychological / Q000187:drug effects; D018755:GABA Agonists / Q000008:administration & dosage*; D008297:Male; D008845:Microinjections; D009042:Motivation / Q000502:physiology; D009118:Muscimol / Q000008:administration & dosage; D009538:Nicotine / Q000494:pharmacology*; D018722:Nicotinic Agonists / Q000494:pharmacology*; D051381:Rats; D012055:Reinforcement Schedule; D012646:Self Administration; D014029:Tobacco Use Disorder / Q000517:prevention & control*
D004338:Drug Combinations; D018755:GABA Agonists; D018722:Nicotinic Agonists; D009118:Muscimol; D009538:Nicotine; D001418:Baclofen