Effect of a serine-to-aspartate replacement on the recognition of chitin oligosaccharides by truncated hevein. A 3D view by using NMR.
Chávez
María Isabel
MI
Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Vila-Perelló
Miquel
M
Cañada
Francisco Javier
FJ
Andreu
David
D
Jiménez-Barbero
Jesús
J
D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry*; D001224:Aspartic Acid; D002686:Chitin / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009154:Mutation; D009844:Oligosaccharides / Q000737:chemistry / Q000378:metabolism*; D010446:Peptide Fragments / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D037121:Plant Lectins / Q000737:chemistry*; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D012694:Serine; D013329:Structure-Activity Relationship; D013816:Thermodynamics
D023181:Antimicrobial Cationic Peptides; D008024:Ligands; D009844:Oligosaccharides; D010446:Peptide Fragments; D037121:Plant Lectins; C045875:hevein; D002686:Chitin; D001224:Aspartic Acid; D012694:Serine