The signalling role of action potential depolarization in insulin secretion: metabolism-dependent dissociation between action potential increase and secretion increase by TEA.
Willenborg
M
M
Institute of Pharmacology and Toxicology, Technical University of Braunschweig, Mendelssohnstr. 1, D-38106 Braunschweig, Germany.
Ghaly
H
H
Hatlapatka
K
K
Urban
K
K
Panten
U
U
Rustenbeck
I
I
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000378:metabolism; D054086:KATP Channels / Q000378:metabolism; D007651:Keto Acids / Q000494:pharmacology; D008564:Membrane Potentials / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains; D026902:Potassium Channel Blockers / Q000494:pharmacology*; D024661:Potassium Channels, Inwardly Rectifying / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects*; D019789:Tetraethylammonium / Q000494:pharmacology*
D007328:Insulin; D054086:KATP Channels; D007651:Keto Acids; D026902:Potassium Channel Blockers; D024661:Potassium Channels, Inwardly Rectifying; D019789:Tetraethylammonium; C013082:alpha-ketoisocaproic acid