title: Trifluoromethyl-promoted homocamptothecins: synthesis and biological activity.
authors.affiliation: School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, People's Republic of China.
authors.forename: Lingjian
authors.initials: L
authors.lastname: Zhu
authors.forename: Zhenyuan
authors.initials: Z
authors.lastname: Miao
authors.forename: Chunquan
authors.initials: C
authors.lastname: Sheng
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Yao
authors.forename: Wenfeng
authors.initials: W
authors.lastname: Liu
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Che
authors.forename: Wenya
authors.initials: W
authors.lastname: Wang
authors.forename: Pengfei
authors.initials: P
authors.lastname: Cheng
authors.forename: Wannian
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D004264:DNA Topoisomerases, Type I / Q000378:metabolism; D054879:Halogenation; D006801:Humans; D008297:Male; D051379:Mice; D059004:Topoisomerase I Inhibitors
chemical_list: D000970:Antineoplastic Agents; D059004:Topoisomerase I Inhibitors; D004247:DNA; C120029:homocamptothecin; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin