title: An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors.
authors.affiliation: Molecular Neurobiology group, Department of Neuroscience, Max-Delbrück Center for Molecular Medicine, Robert-Rössle Strasse 10, 13125 Berlin, Germany.
authors.forename: Annika S
authors.initials: AS
authors.lastname: Stürzebecher
authors.forename: Jing
authors.initials: J
authors.lastname: Hu
authors.forename: Ewan St John
authors.initials: ES
authors.lastname: Smith
authors.forename: Silke
authors.initials: S
authors.lastname: Frahm
authors.forename: Julio
authors.initials: J
authors.lastname: Santos-Torres
authors.forename: Branka
authors.initials: B
authors.lastname: Kampfrath
authors.forename: Sebastian
authors.initials: S
authors.lastname: Auer
authors.forename: Gary R
authors.initials: GR
authors.lastname: Lewin
authors.forename: Inés
authors.initials: I
authors.lastname: Ibañez-Tallon
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D015139:Blotting, Southern; D022202:Chromosomes, Artificial, Bacterial / Q000235:genetics; D020916:Conotoxins / Q000737:chemistry / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis / Q000235:genetics; D004594:Electrophysiology; D005260:Female; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D015640:Ion Channel Gating / Q000187:drug effects / Q000235:genetics; D051379:Mice; D008822:Mice, Transgenic; D009475:Neurons, Afferent / Q000187:drug effects; D009619:Nociceptors / Q000187:drug effects* / Q000502:physiology; D009865:Oocytes / Q000502:physiology; D010146:Pain / Q000523:psychology; D018408:Patch-Clamp Techniques; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012867:Skin / Q000294:innervation; D026941:Sodium Channel Blockers / Q000737:chemistry / Q000494:pharmacology*; D015222:Sodium Channels / Q000187:drug effects* / Q000235:genetics; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism; D014982:Xenopus laevis
chemical_list: D020916:Conotoxins; D026941:Sodium Channel Blockers; D015222:Sodium Channels; C093338:conotoxin MrVIA; D004247:DNA