Small-molecule affinity ligands for protein purification: combined computational enrichment and automated in-line screening of an optically encoded library.
Rasmussen
Jakob E
JE
Protein Engineering, Novo Nordisk A/S, Novo Nordisk Park, 2760 Måløv, Denmark. jera@life.ku.dk
Schiødt
Christine B
CB
Christensen
Søren F
SF
Nørskov-Lauritsen
Leif
L
Meldal
Morten
M
St Hilaire
Phaedria M
PM
Jensen
Knud J
KJ
D057205:Automation, Laboratory; D019295:Computational Biology; D019382:Human Growth Hormone / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D008024:Ligands; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D054852:Small Molecule Libraries / Q000737:chemistry*
D008024:Ligands; D054852:Small Molecule Libraries; D019382:Human Growth Hormone