N-acetylcysteine protects striated muscle in a model of compartment syndrome.
Kearns
Stephen R
SR
Department of Orthopaedics, Galway University Hospitals, Newcastle Road, Galway, Ireland. lowerlimb@gmail.com
O'Briain
David E
DE
Sheehan
Katherine M
KM
Kelly
Cathal
C
Bouchier-Hayes
David
D
D000111:Acetylcysteine / Q000494:pharmacology*; D000818:Animals; D003161:Compartment Syndromes / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D004195:Disease Models, Animal; D016166:Free Radical Scavengers / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000201:enzymology / Q000503:physiopathology; D020556:Neutrophil Infiltration / Q000187:drug effects / Q000502:physiology; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology; D018384:Oxidative Stress / Q000187:drug effects; D009195:Peroxidase / Q000378:metabolism; D011312:Pressure / Q000009:adverse effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D016897:Respiratory Burst / Q000187:drug effects; D013997:Time Factors
D016166:Free Radical Scavengers; D009195:Peroxidase; D000111:Acetylcysteine