The leader peptide of a human rec. MnSOD as molecular carrier which delivers high amounts of Cisplatin into tumor cells inducing a fast apoptosis in vitro.
Borrelli
Antonella
A
Department of Molecular Biology and Viral Oncogenesis N.C.I. of Naples, Naples, Italy.
Schiattarella
Antonietta
A
Mancini
Roberto
R
Morelli
Franco
F
Capasso
Clemente
C
De Luca
Viviana
V
Gori
Enrico
E
Mancini
Aldo
A
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000008:administration & dosage*; D004337:Drug Carriers; D048049:Extracellular Signal-Regulated MAP Kinases / Q000037:antagonists & inhibitors; D005419:Flavonoids / Q000494:pharmacology; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016133:Polymerase Chain Reaction; D021382:Protein Sorting Signals; D013054:Spectrophotometry, Atomic; D013482:Superoxide Dismutase / Q000008:administration & dosage*; D051028:bcl-2-Associated X Protein / Q000235:genetics
D000970:Antineoplastic Agents; C494826:BAX protein, human; D004337:Drug Carriers; D005419:Flavonoids; D021382:Protein Sorting Signals; D051028:bcl-2-Associated X Protein; D013482:Superoxide Dismutase; D048049:Extracellular Signal-Regulated MAP Kinases; D002945:Cisplatin; C093973:2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one