Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.
Chutkow
William A
WA
Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Cambridge, Massachusetts, USA.
Birkenfeld
Andreas L
AL
Brown
Jonathan D
JD
Lee
Hui-Young
HY
Frederick
David W
DW
Yoshioka
Jun
J
Patwari
Parth
P
Kursawe
Romy
R
Cushman
Samuel W
SW
Plutzky
Jorge
J
Shulman
Gerald I
GI
Samuel
Varman T
VT
Lee
Richard T
RT
D016475:3T3 Cells / Q000502:physiology; D050154:Adiposity / Q000235:genetics*; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics*; D004041:Dietary Fats; D017353:Gene Deletion; D005786:Gene Expression Regulation; D015309:Glucose Clamp Technique; D006801:Humans; D006946:Hyperinsulinism; D007328:Insulin / Q000494:pharmacology / Q000502:physiology*; D007333:Insulin Resistance / Q000235:genetics; D051379:Mice; D018345:Mice, Knockout; D009765:Obesity / Q000235:genetics; D018384:Oxidative Stress / Q000502:physiology; D013879:Thioredoxins / Q000235:genetics*
D001786:Blood Glucose; D002352:Carrier Proteins; D004041:Dietary Fats; D007328:Insulin; C445672:Txnip protein, mouse; D013879:Thioredoxins