Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice.
Lin
Yung-Feng
YF
Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Xu
Xingshun
X
Cape
Austin
A
Li
Shihua
S
Li
Xiao-Jiang
XJ
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D004435:Eating / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D006801:Humans; D000071058:Huntingtin Protein; D006816:Huntington Disease / Q000235:genetics / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D018345:Mice, Knockout; D009043:Motor Activity / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000096:biosynthesis*; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D000068797:Orexins; D013574:Synaptosomes / Q000378:metabolism
C490758:Hap1 protein, mouse; C506812:Htt protein, mouse; D000071058:Huntingtin Protein; D047908:Intracellular Signaling Peptides and Proteins; D009419:Nerve Tissue Proteins; D009479:Neuropeptides; D009687:Nuclear Proteins; D000068797:Orexins