Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.
Evindar
Ghotas
G
Department of Medicinal Chemistry, Praecis Pharmaceuticals Incorporated, Waltham, MA 02451, USA. ghotas.x.evindar@gsk.com
Bernier
Sylvie G
SG
Doyle
Elisabeth
E
Kavarana
Malcolm J
MJ
Satz
Alexander L
AL
Lorusso
Jeanine
J
Blanchette
Heather S
HS
Saha
Ashis K
AK
Hannig
Gerhard
G
Morgan
Barry A
BA
Westlin
William F
WF
D000284:Administration, Oral; D000605:Amino Alcohols / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D051379:Mice; D049349:Receptors, Lysosphingolipid / Q000819:agonists*; D013329:Structure-Activity Relationship
D000605:Amino Alcohols; D049349:Receptors, Lysosphingolipid