title: Discovery of fragment molecules that bind the human peroxiredoxin 5 active site.
authors.affiliation: Laboratory of Analytical Sciences (UMR CNRS 5180), Université Claude Bernard-Lyon 1, Bât. ESCPE Lyon, Domaine scientifique de la Doua, Villeurbanne, France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Barelier
authors.forename: Dominique
authors.initials: D
authors.lastname: Linard
authors.forename: Julien
authors.initials: J
authors.lastname: Pons
authors.forename: André
authors.initials: A
authors.lastname: Clippe
authors.forename: Bernard
authors.initials: B
authors.lastname: Knoops
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Lancelin
authors.forename: Isabelle
authors.initials: I
authors.lastname: Krimm
mesh_terms: D001665:Binding Sites; D020134:Catalytic Domain; D018360:Crystallography, X-Ray / Q000379:methods; D003545:Cysteine / Q000737:chemistry; D006801:Humans; D007700:Kinetics; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008956:Models, Chemical; D008958:Models, Molecular; D010544:Peroxidases / Q000737:chemistry; D054464:Peroxiredoxins / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: D008024:Ligands; D010544:Peroxidases; D054464:Peroxiredoxins; D003545:Cysteine