Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association.
Andreetto
Erika
E
Laboratory of Peptide Biochemistry, Center of Integrated Protein Science, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising-Weihenstephan, Germany.
Yan
Li-Mei
LM
Tatarek-Nossol
Marianna
M
Velkova
Aleksandra
A
Frank
Ronald
R
Kapurniotu
Aphrodite
A
D000544:Alzheimer Disease / Q000378:metabolism; D000595:Amino Acid Sequence; D000682:Amyloid / Q000737:chemistry / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism; D006801:Humans; D058228:Islet Amyloid Polypeptide; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding
D000682:Amyloid; D016229:Amyloid beta-Peptides; D058228:Islet Amyloid Polypeptide; D010446:Peptide Fragments; C078592:amyloid beta-protein (1-40)