Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A).
Lan
Fei-Fei
FF
Laboratory of Integrated Biosciences, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Wang
Hua
H
Chen
Yang-Chao
YC
Chan
Chu-Yan
CY
Ng
Samuel S
SS
Li
Kui
K
Xie
Dan
D
He
Ming-Liang
ML
Lin
Marie C
MC
Kung
Hsiang-Fu
HF
D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000517:prevention & control*; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D019941:Cyclin-Dependent Kinase Inhibitor p16; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000517:prevention & control*; D035683:MicroRNAs / Q000235:genetics / Q000502:physiology*; D009363:Neoplasm Proteins / Q000235:genetics*; D014176:Protein Biosynthesis; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics*; D014158:Transcription, Genetic
C000614131:CDKN2A protein, human; D019941:Cyclin-Dependent Kinase Inhibitor p16; C489427:MYC protein, human; D035683:MicroRNAs; D009363:Neoplasm Proteins; D016271:Proto-Oncogene Proteins c-myc; C487931:mirnlet7 microRNA, human