Bifidobacterium lactis inhibits NF-kappaB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice.
Kim
Seung Won
SW
Department of Internal Medicine and Institute of Gastroenterology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Kim
Hee Man
HM
Yang
Kyoung Min
KM
Kim
Sun-Ah
SA
Kim
Sung-Kyu
SK
An
Min Ji
MJ
Park
Jae Jun
JJ
Lee
Sang Kil
SK
Kim
Tae Il
TI
Kim
Won Ho
WH
Cheon
Jae Hee
JH
D000208:Acute Disease; D000818:Animals; D001397:Azoxymethane / Q000633:toxicity; D039941:Bifidobacteriales Infections / Q000517:prevention & control; D001644:Bifidobacterium / Q000502:physiology*; D015153:Blotting, Western; D002273:Carcinogens / Q000633:toxicity; D002908:Chronic Disease; D003092:Colitis / Q000139:chemically induced / Q000150:complications / Q000517:prevention & control*; D003106:Colon / Q000378:metabolism / Q000382:microbiology / Q000473:pathology; D003110:Colonic Neoplasms / Q000139:chemically induced / Q000150:complications / Q000517:prevention & control*; D016264:Dextran Sulfate / Q000633:toxicity; D024202:Electrophoretic Mobility Shift Assay; D004797:Enzyme-Linked Immunosorbent Assay; D004847:Epithelial Cells / Q000378:metabolism / Q000382:microbiology* / Q000473:pathology; D007124:Immunoenzyme Techniques; D007249:Inflammation / Q000139:chemically induced / Q000150:complications / Q000517:prevention & control; D007413:Intestinal Mucosa / Q000378:metabolism / Q000382:microbiology* / Q000473:pathology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008156:Luciferases / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D016328:NF-kappa B / Q000037:antagonists & inhibitors* / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
D002273:Carcinogens; D008070:Lipopolysaccharides; D016328:NF-kappa B; D012333:RNA, Messenger; D016264:Dextran Sulfate; D008156:Luciferases; D001397:Azoxymethane