title: Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells.
authors.affiliation: Immunology and Oncology Unit, Calvary Mater Newcastle Hospital, Newcastle, NSW 2300, Australia.
authors.forename: F
authors.initials: F
authors.lastname: Yang
authors.forename: K H
authors.initials: KH
authors.lastname: Tay
authors.forename: L
authors.initials: L
authors.lastname: Dong
authors.forename: R F
authors.initials: RF
authors.lastname: Thorne
authors.forename: C C
authors.initials: CC
authors.lastname: Jiang
authors.forename: E
authors.initials: E
authors.lastname: Yang
authors.forename: H-Y
authors.initials: HY
authors.lastname: Tseng
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: R
authors.initials: R
authors.lastname: Christopherson
authors.forename: P
authors.initials: P
authors.lastname: Hersey
authors.forename: X D
authors.initials: XD
authors.lastname: Zhang
mesh_terms: D017209:Apoptosis; D053446:CASP8 and FADD-Like Apoptosis Regulating Protein / Q000378:metabolism*; D053181:Caspase 8 / Q000378:metabolism; D045744:Cell Line, Tumor; D055313:Cystatin B / Q000235:genetics / Q000378:metabolism*; D055785:Gene Knockdown Techniques; D006801:Humans; D008545:Melanoma / Q000201:enzymology / Q000378:metabolism*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000378:metabolism; D012097:Repressor Proteins / Q000378:metabolism*; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000494:pharmacology*; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism*
chemical_list: D053446:CASP8 and FADD-Like Apoptosis Regulating Protein; D034741:RNA, Small Interfering; D012097:Repressor Proteins; D053221:TNF-Related Apoptosis-Inducing Ligand; D055313:Cystatin B; C432966:ITCH protein, human; D044767:Ubiquitin-Protein Ligases; D053181:Caspase 8