A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties.
Song
Eun Suk
ES
Department of Molecular and Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America.
Rodgers
David W
DW
Hersh
Louis B
LB
D000495:Allosteric Site; D016229:Amyloid beta-Peptides / Q000235:genetics; D000818:Animals; D019281:Dimerization; D015971:Gene Expression Regulation, Enzymologic; D007313:Insecta; D007339:Insulysin / Q000235:genetics*; D007700:Kinetics; D010455:Peptides / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D051381:Rats; D013379:Substrate Specificity; D001615:beta-Endorphin / Q000235:genetics
D016229:Amyloid beta-Peptides; D010455:Peptides; D010710:Phosphates; D001615:beta-Endorphin; D007339:Insulysin