Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.
Rowbotham
Sophie E
SE
Northern Institute for Cancer Research, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom. sophie.rowbotham@cancer.org.uk
Illingworth
Nicola A
NA
Daly
Ann K
AK
Veal
Gareth J
GJ
Boddy
Alan V
AV
D020719:Glucuronides / Q000493:pharmacokinetics; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism*; D015474:Isotretinoin / Q000493:pharmacokinetics*; D007700:Kinetics; D008861:Microsomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology; D013379:Substrate Specificity; D014212:Tretinoin / Q000031:analogs & derivatives* / Q000493:pharmacokinetics
D020719:Glucuronides; D007527:Isoenzymes; C002202:4-oxoretinoic acid; D014212:Tretinoin; D014453:Glucuronosyltransferase; D015474:Isotretinoin