A fluorescence correlation spectroscopy-based assay for fragment screening of slowly inhibiting protein-peptide interaction inhibitors.
Mikuni
Junko
J
RIKEN Systems and Structural Biology Center, Tsurumi, Yokohama 230-0045, Japan.
Kato
Miki
M
Taruya
Shigenao
S
Tsuganezawa
Keiko
K
Mori
Masumi
M
Ogawa
Naoko
N
Honma
Teruki
T
Yokoyama
Shigeyuki
S
Kojima
Hirotatsu
H
Okabe
Takayoshi
T
Nagano
Tetsuo
T
Tanaka
Akiko
A
D000818:Animals; D001667:Binding, Competitive; D051379:Mice; D010455:Peptides / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D010748:Phosphopeptides / Q000037:antagonists & inhibitors / Q000378:metabolism; D011485:Protein Binding / Q000187:drug effects; D025941:Protein Interaction Mapping; D011506:Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D050721:Proto-Oncogene Proteins c-cbl / Q000037:antagonists & inhibitors / Q000378:metabolism; D013050:Spectrometry, Fluorescence / Q000379:methods*
D010455:Peptides; D010748:Phosphopeptides; D011506:Proteins; D050721:Proto-Oncogene Proteins c-cbl; C493849:Cbl protein, mouse