The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.
Zaki
Md Hasan
MH
Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Boyd
Kelli L
KL
Vogel
Peter
P
Kastan
Michael B
MB
Lamkanfi
Mohamed
M
Kanneganti
Thirumala-Devi
TD
D000818:Animals; D051017:Apoptosis Regulatory Proteins; D053468:CARD Signaling Adaptor Proteins; D002352:Carrier Proteins / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D049109:Cell Proliferation; D003092:Colitis / Q000139:chemically induced / Q000276:immunology* / Q000382:microbiology / Q000473:pathology*; D003598:Cytoskeletal Proteins / Q000276:immunology; D016264:Dextran Sulfate; D004195:Disease Models, Animal; D004847:Epithelial Cells / Q000166:cytology / Q000276:immunology*; D020382:Interleukin-18 / Q000096:biosynthesis / Q000276:immunology; D007408:Intestinal Absorption; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D015398:Signal Transduction
D051017:Apoptosis Regulatory Proteins; D053468:CARD Signaling Adaptor Proteins; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; D020382:Interleukin-18; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C492716:Nlrp3 protein, mouse; C498534:Pycard protein, mouse; D016264:Dextran Sulfate