Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes.
Saha
Sudipta
S
Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore.
New
Lee Sun
LS
Ho
Han Kiat
HK
Chui
Wai Keung
WK
Chan
Eric Chun Yong
EC
D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002839:Chromans / Q000633:toxicity; D005978:Glutathione / Q000378:metabolism; D022781:Hepatocytes / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects; D050050:Protein Carbonylation / Q000187:drug effects; D015238:Sulfotransferases / Q000037:antagonists & inhibitors; D013463:Sulfuric Acid Esters / Q000737:chemistry / Q000633:toxicity*; D045162:Thiazolidinediones / Q000737:chemistry / Q000633:toxicity*; D000077288:Troglitazone
D002839:Chromans; D007004:Hypoglycemic Agents; D013463:Sulfuric Acid Esters; D045162:Thiazolidinediones; C549564:troglitazone sulfate; D015238:Sulfotransferases; D005978:Glutathione; D000077288:Troglitazone