Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.
Hoi
Charlene S L
CS
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
Lee
Song Eun
SE
Lu
Shu-Yang
SY
McDermitt
David J
DJ
Osorio
Karen M
KM
Piskun
Caroline M
CM
Peters
Rachel M
RM
Paus
Ralf
R
Tumbar
Tudorita
T
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002453:Cell Cycle / Q000502:physiology; D019070:Cell Lineage; D049109:Cell Proliferation; D002478:Cells, Cultured; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics / Q000378:metabolism*; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000235:genetics / Q000378:metabolism; D005260:Female; D018859:Hair Follicle / Q000166:cytology* / Q000502:physiology; D006801:Humans; D015603:Keratinocytes / Q000166:cytology / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009375:Neoplasms, Glandular and Epithelial / Q000378:metabolism* / Q000473:pathology; D010641:Phenotype; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012867:Skin / Q000166:cytology / Q000378:metabolism / Q000473:pathology*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*
D015415:Biomarkers; C493957:Cdkn1a protein, mouse; D050676:Core Binding Factor Alpha 2 Subunit; D050759:Cyclin-Dependent Kinase Inhibitor p21; D011993:Recombinant Fusion Proteins