Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma.
Balyasnikova
Irina V
IV
The Brain Tumor Center, The University of Chicago, Chicago, Illinois, United States of America.
Ferguson
Sherise D
SD
Sengupta
Sadhak
S
Han
Yu
Y
Lesniak
Maciej S
MS
D000818:Animals; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D018920:Coculture Techniques; D066246:ErbB Receptors / Q000235:genetics*; D005434:Flow Cytometry / Q000379:methods; D005910:Glioma / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D051379:Mice; D009368:Neoplasm Transplantation; D009389:Neovascularization, Pathologic; D010766:Phosphorylation; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000096:biosynthesis
D019408:Platelet Endothelial Cell Adhesion Molecule-1; C410723:epidermal growth factor receptor VIII; D066246:ErbB Receptors