Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.
Guo
Naxin
N
Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Baglole
Carolyn J
CJ
O'Loughlin
Charles W
CW
Feldon
Steven E
SE
Phipps
Richard P
RP
D017667:Adipocytes / Q000378:metabolism / Q000473:pathology; D050156:Adipogenesis / Q000187:drug effects; D002478:Cells, Cultured; D018920:Coculture Techniques; D005128:Eye Diseases / Q000378:metabolism* / Q000473:pathology; D005347:Fibroblasts / Q000378:metabolism* / Q000473:pathology; D014453:Glucuronosyltransferase / Q000378:metabolism; D000076002:Hyaluronan Synthases; D006820:Hyaluronic Acid / Q000096:biosynthesis*; D006827:Hydantoins / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology; D007527:Isoenzymes / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism* / Q000473:pathology; D009915:Orbit / Q000378:metabolism / Q000473:pathology; D015230:Prostaglandin D2 / Q000031:analogs & derivatives / Q000378:metabolism*; D011982:Receptors, Prostaglandin / Q000819:agonists / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013959:Thyroid Diseases / Q000378:metabolism* / Q000473:pathology
D006827:Hydantoins; D007211:Indoles; D007527:Isoenzymes; C518174:MK-0524; D011982:Receptors, Prostaglandin; C501562:prostanoid D receptor 1, human; C037112:9-deoxy-delta-9-prostaglandin D2; C030669:BW 245C; D006820:Hyaluronic Acid; D014453:Glucuronosyltransferase; C523794:HAS1 protein, human; C101754:HAS2 protein, human; D000076002:Hyaluronan Synthases; D015230:Prostaglandin D2