ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell.
Jacques-Silva
M Caroline
MC
Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Correa-Medina
Mayrin
M
Cabrera
Over
O
Rodriguez-Diaz
Rayner
R
Makeeva
Natalia
N
Fachado
Alberto
A
Diez
Juan
J
Berman
Dora M
DM
Kenyon
Norma S
NS
Ricordi
Camillo
C
Pileggi
Antonello
A
Molano
R Damaris
RD
Berggren
Per-Olof
PO
Caicedo
Alejandro
A
D000255:Adenosine Triphosphate / Q000378:metabolism*; D019898:Autocrine Communication; D002118:Calcium / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000378:metabolism*; D018048:Receptors, Purinergic P2 / Q000235:genetics / Q000378:metabolism*; D058477:Receptors, Purinergic P2X3; D015398:Signal Transduction
D007328:Insulin; C546407:P2RX3 protein, human; D018048:Receptors, Purinergic P2; D058477:Receptors, Purinergic P2X3; D000255:Adenosine Triphosphate; D002118:Calcium