Detection and in-cell selectivity profiling of the full-length West Nile virus NS2B/NS3 serine protease using membrane-anchored fluorescent substrates.
Condotta
Stephanie A
SA
Department of Microbiology and Immunology, Life Sciences Center, the University of British Columbia, Vancouver, Canada.
Martin
Morgan M
MM
Boutin
Martine
M
Jean
François
F
D000818:Animals; D004721:Endoplasmic Reticulum / Q000201:enzymology; D005456:Fluorescent Dyes; D006801:Humans; D007425:Intracellular Membranes / Q000201:enzymology; D008164:Luminescent Proteins; D008856:Microscopy, Fluorescence; D012697:Serine Endopeptidases / Q000032:analysis*; D013379:Substrate Specificity; D014162:Transfection; D014407:Tumor Cells, Cultured; D017361:Viral Nonstructural Proteins; D014902:West Nile virus / Q000201:enzymology*
D005456:Fluorescent Dyes; D008164:Luminescent Proteins; D017361:Viral Nonstructural Proteins; C413663:fluorescent protein 583; D012697:Serine Endopeptidases