Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease.
Gross
Oliver
O
Department of Nephrology & Rheumatology, University Medicine Goettingen Robert-Koch Strasse 40, Goettingen, Germany. gross.oliver@med.uni-goettingen.de
Girgert
Rainer
R
Beirowski
Bogdan
B
Kretzler
Matthias
M
Kang
Hee Gyung
HG
Kruegel
Jenny
J
Miosge
Nicolai
N
Busse
Ann-Christin
AC
Segerer
Stephan
S
Vogel
Wolfgang F
WF
Müller
Gerhard-Anton
GA
Weber
Manfred
M
D000818:Animals; D017252:CD3 Complex / Q000378:metabolism; D024141:Collagen Type IV / Q000235:genetics / Q000378:metabolism*; D055513:Connective Tissue Growth Factor / Q000378:metabolism; D000070819:Discoidin Domain Receptor 1; D005260:Female; D005355:Fibrosis / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D007678:Kidney Glomerulus / Q000378:metabolism / Q000503:physiopathology* / Q000648:ultrastructure; D008136:Longevity; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018345:Mice, Knockout; D008854:Microscopy, Electron; D016328:NF-kappa B / Q000378:metabolism; D009394:Nephritis, Hereditary / Q000378:metabolism / Q000503:physiopathology*; D011507:Proteinuria / Q000378:metabolism; D012313:RNA / Q000737:chemistry / Q000235:genetics; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016212:Transforming Growth Factor beta / Q000378:metabolism; D014508:Urea / Q000097:blood
C526318:CCN2 protein, mouse; D017252:CD3 Complex; D024141:Collagen Type IV; D016328:NF-kappa B; D016212:Transforming Growth Factor beta; D055513:Connective Tissue Growth Factor; D012313:RNA; D014508:Urea; C083249:Ddr1 protein, mouse; D000070819:Discoidin Domain Receptor 1; D020794:Receptor Protein-Tyrosine Kinases