Discovery of inhibitors of brassinin oxidase based on the scaffolds of the phytoalexins brassilexin and wasalexin.
Pedras
M Soledade C
MS
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Canada SK S7N 5C9. soledade.pedras@usask.ca
Minic
Zoran
Z
Sarma-Mamillapalle
Vijay K
VK
Suchy
Mojmir
M
D002851:Chromatography, High Pressure Liquid; D055808:Drug Discovery; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D007202:Indicators and Reagents; D007211:Indoles / Q000737:chemistry*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D021241:Spectrometry, Mass, Electrospray Ionization; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013440:Sulfides / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*
D004791:Enzyme Inhibitors; D007202:Indicators and Reagents; D007211:Indoles; D013440:Sulfides; D013844:Thiazoles; C401941:wasalexin A; C430121:brassilexin; D010088:Oxidoreductases; C540356:brassinin oxidase, Leptosphaeriae maculans