Hyaluronan induces migration of multidrug-resistant lymphoma cell lines in vitro through Tiam1 activation by a PI3K-dependent mechanism.
Cordo-Russo
Rosalía I
RI
Department of Immunology, School of Pharmacy and Biochemistry, University of Buenos Aires, IDEHU-CONICET, Buenos Aires, Argentina. rosaliacordorusso@yahoo.com.ar
Alaniz
Laura D
LD
Saccodossi
Natalia
N
Lompardía
Silvina
S
Blanco
Guillermo
G
Alvarez
Elida
E
García
Mariana G
MG
Hajos
Silvia E
SE
D000818:Animals; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects*; D018432:Drug Resistance, Multiple; D020662:Guanine Nucleotide Exchange Factors / Q000378:metabolism*; D006820:Hyaluronic Acid / Q000494:pharmacology*; D008223:Lymphoma / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D015398:Signal Transduction; D000075684:T-Lymphoma Invasion and Metastasis-inducing Protein 1
D020662:Guanine Nucleotide Exchange Factors; D000075684:T-Lymphoma Invasion and Metastasis-inducing Protein 1; C087334:TIAM1 protein, human; D006820:Hyaluronic Acid; D019869:Phosphatidylinositol 3-Kinases