title: Synthesis of 26-hydroxy-22-oxocholestanic frameworks from diosgenin and hecogenin and their in vitro antiproliferative and apoptotic activity on human cervical cancer CaSki cells.
authors.affiliation: Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Ciudad Universitaria, 72570 Puebla, Pue., Mexico.
authors.forename: María A
authors.initials: MA
authors.lastname: Fernández-Herrera
authors.forename: Hugo
authors.initials: H
authors.lastname: López-Muñoz
authors.forename: José M V
authors.initials: JM
authors.lastname: Hernández-Vázquez
authors.forename: Moisés
authors.initials: M
authors.lastname: López-Dávila
authors.forename: María L
authors.initials: ML
authors.lastname: Escobar-Sánchez
authors.forename: Luis
authors.initials: L
authors.lastname: Sánchez-Sánchez
authors.forename: B Mario
authors.initials: BM
authors.lastname: Pinto
authors.forename: Jesús
authors.initials: J
authors.lastname: Sandoval-Ramírez
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis* / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002240:Carbohydrate Sequence; D053148:Caspase 3 / Q000378:metabolism; D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002777:Cholestanols / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology*; D053938:DNA Fragmentation / Q000187:drug effects; D004144:Diosgenin / Q000737:chemistry*; D005260:Female; D005347:Fibroblasts / Q000187:drug effects; D005456:Fluorescent Dyes; D006801:Humans; D020287:In Situ Nick-End Labeling; D007211:Indoles; D008214:Lymphocytes / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D012502:Sapogenins / Q000737:chemistry*; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D002777:Cholestanols; D005456:Fluorescent Dyes; D007211:Indoles; D012502:Sapogenins; D013256:Steroids; C007908:hecogenin; C007293:DAPI; D053148:Caspase 3; D004144:Diosgenin