Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease.
Greco
Steven J
SJ
Neurotez, Inc, Bridgewater, NJ 08807, USA.
Bryan
Kathryn J
KJ
Sarkar
Sraboni
S
Zhu
Xiongwei
X
Smith
Mark A
MA
Ashford
J Wesson
JW
Johnston
Jane M
JM
Tezapsidis
Nikolaos
N
Casadesus
Gemma
G
D000544:Alzheimer Disease / Q000378:metabolism* / Q000473:pathology*; D053829:Amyloid Precursor Protein Secretases / Q000378:metabolism; D000818:Animals; D002097:C-Reactive Protein / Q000378:metabolism; D003213:Conditioning, Psychological; D004195:Disease Models, Animal; D005239:Fear; D006624:Hippocampus / Q000378:metabolism / Q000473:pathology; D007150:Immunohistochemistry; D015918:Infusion Pumps, Implantable; D020738:Leptin / Q000008:administration & dosage* / Q000378:metabolism*; D008569:Memory Disorders / Q000378:metabolism*; D051379:Mice; D008822:Mice, Transgenic; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D010766:Phosphorylation; D021641:Recognition, Psychology; D016875:tau Proteins / Q000378:metabolism
D020738:Leptin; D016875:tau Proteins; D002097:C-Reactive Protein; D053829:Amyloid Precursor Protein Secretases