title: 1,7-Disubstituted oxyindoles are potent and selective EP(3) receptor antagonists.
authors.affiliation: deCODE Chemistry, Woodridge, IL 60517, USA.
authors.forename: Nian
authors.initials: N
authors.lastname: Zhou
authors.forename: Alexandre M
authors.initials: AM
authors.lastname: Polozov
authors.forename: Matthew
authors.initials: M
authors.lastname: O'Connell
authors.forename: James
authors.initials: J
authors.lastname: Burgeson
authors.forename: Peng
authors.initials: P
authors.lastname: Yu
authors.forename: Wayne
authors.initials: W
authors.lastname: Zeller
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Onua
authors.forename: Jose
authors.initials: J
authors.lastname: Ramirez
authors.forename: Gudrun A
authors.initials: GA
authors.lastname: Palsdottir
authors.forename: Gudrun V
authors.initials: GV
authors.lastname: Halldorsdottir
authors.forename: Thorkell
authors.initials: T
authors.lastname: Andresson
authors.forename: Alex S
authors.initials: AS
authors.lastname: Kiselyov
authors.forename: Mark
authors.initials: M
authors.lastname: Gurney
authors.forename: Jasbir
authors.initials: J
authors.lastname: Singh
mesh_terms: D000818:Animals; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D018078:Receptors, Prostaglandin E / Q000037:antagonists & inhibitors*; D058308:Receptors, Prostaglandin E, EP3 Subtype
chemical_list: D007211:Indoles; D010975:Platelet Aggregation Inhibitors; C545649:Ptger3 protein, rat; D018078:Receptors, Prostaglandin E; D058308:Receptors, Prostaglandin E, EP3 Subtype