The involvement of ROS overproduction and mitochondrial dysfunction in PBDE-47-induced apoptosis on Jurkat cells.
Yan
Chuan
C
School of Life Sciences, Lanzhou University, Lanzhou 730000, PR China.
Huang
Dejun
D
Zhang
Yingmei
Y
D000111:Acetylcysteine / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D018929:Cell Culture Techniques; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004785:Environmental Pollutants / Q000633:toxicity*; D016166:Free Radical Scavengers / Q000494:pharmacology; D055768:Halogenated Diphenyl Ethers / Q000633:toxicity*; D006801:Humans; D019169:Jurkat Cells; D053078:Membrane Potential, Mitochondrial / Q000187:drug effects*; D017382:Reactive Oxygen Species / Q000378:metabolism*
D004785:Environmental Pollutants; D016166:Free Radical Scavengers; D055768:Halogenated Diphenyl Ethers; D017382:Reactive Oxygen Species; C511295:2,2',4,4'-tetrabromodiphenyl ether; D000111:Acetylcysteine