Strategies for developing design spaces for viral clearance by anion exchange chromatography during monoclonal antibody production.
Strauss
Daniel M
DM
Process Research and Development, Genentech, Inc., One DNA Way, South San Francisco, CA 94080, USA.
Cano
Tony
T
Cai
Nick
N
Delucchi
Heather
H
Plancarte
Magdalena
M
Coleman
Daniel
D
Blank
Gregory S
GS
Chen
Qi
Q
Yang
Bin
B
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000737:chemistry; D016466:CHO Cells; D018929:Cell Culture Techniques; D002852:Chromatography, Ion Exchange / Q000379:methods*; D006224:Cricetinae; D003412:Cricetulus; D012107:Research Design; D018570:Risk Assessment; D014780:Viruses / Q000302:isolation & purification*
D000911:Antibodies, Monoclonal