Oleamide suppresses lipopolysaccharide-induced expression of iNOS and COX-2 through inhibition of NF-kappaB activation in BV2 murine microglial cells.
Oh
Young Taek
YT
Department of Biochemistry and Molecular Biology, School of Medicine, Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, Biomedical Science Institute, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
Lee
Jung Yeon
JY
Department of Biochemistry and Molecular Biology, School of Medicine, Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, Biomedical Science Institute, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
Lee
Jinhwa
J
Department of Biomedical Laboratory Science, Dongseo University, Busan 617-716, Republic of Korea.
Lee
Ju Hie
JH
Department of Pathology, School of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea.
Kim
Ja-Eun
JE
Department of Pharmacology, School of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea.
Ha
Joohun
J
Department of Biochemistry and Molecular Biology, School of Medicine, Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, Biomedical Science Institute, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
Kang
Insug
I
Department of Biochemistry and Molecular Biology, School of Medicine, Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, Biomedical Science Institute, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea. Electronic address: iskang@khu.ac.kr.
D000818:Animals; D002460:Cell Line; D002469:Cell Separation; D051546:Cyclooxygenase 2 / Q000096:biosynthesis*; D004789:Enzyme Activation / Q000502:physiology; D005434:Flow Cytometry; D015870:Gene Expression; D015151:Immunoblotting; D047468:Immunoprecipitation; D007249:Inflammation / Q000378:metabolism; D018836:Inflammation Mediators / Q000378:metabolism; D008070:Lipopolysaccharides / Q000494:pharmacology; D051379:Mice; D017628:Microglia / Q000378:metabolism*; D016328:NF-kappa B / Q000378:metabolism*; D052247:Nitric Oxide Synthase Type II / Q000096:biosynthesis*; D009829:Oleic Acids / Q000378:metabolism*; D012333:RNA, Messenger / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction
D018836:Inflammation Mediators; D008070:Lipopolysaccharides; D016328:NF-kappa B; D009829:Oleic Acids; D012333:RNA, Messenger; C029407:oleylamide; D052247:Nitric Oxide Synthase Type II; D051546:Cyclooxygenase 2