title: Effects of inoculum, pH, and cations on the in vitro activity of fidaxomicin (OPT-80, PAR-101) against Clostridium difficile.
authors.affiliation: Department of Biology, Optimer Pharmaceuticals, Inc., San Diego, CA 92121, USA. fbabakhani@optimerpharma.com
authors.forename: F
authors.initials: F
authors.lastname: Babakhani
authors.forename: J
authors.initials: J
authors.lastname: Seddon
authors.forename: N
authors.initials: N
authors.lastname: Robert
authors.forename: Y-K
authors.initials: YK
authors.lastname: Shue
authors.forename: P
authors.initials: P
authors.lastname: Sears
mesh_terms: D000362:Agar; D000617:Aminoglycosides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002412:Cations; D016360:Clostridioides difficile / Q000187:drug effects*; D015169:Colony Count, Microbial; D003470:Culture Media; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000382:microbiology; D000077732:Fidaxomicin; D006027:Glycosides / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests / Q000379:methods*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002412:Cations; D003470:Culture Media; D006027:Glycosides; C487655:OPT 80; D000362:Agar; D000077732:Fidaxomicin