Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.
Svensson
Sara L
SL
Section for Respiratory Medicine & Allergology, Department of Clinical Sciences Lund, Lund University, University Hospital, SE-221 85 Lund, Sweden.
Pasupuleti
Mukesh
M
Walse
Björn
B
Malmsten
Martin
M
Mörgelin
Matthias
M
Sjögren
Camilla
C
Olin
Anders I
AI
Collin
Mattias
M
Schmidtchen
Artur
A
Palmer
Ruth
R
Egesten
Arne
A
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism; D002352:Carrier Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D016207:Cytokines / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D029721:Drosophila Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004331:Drosophila melanogaster; D047108:Embryonic Development / Q000502:physiology; D019143:Evolution, Molecular; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry* / Q000378:metabolism; D000078792:Midkine; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D009414:Nerve Growth Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D010449:Peptide Mapping; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D014982:Xenopus laevis; D015027:Zebrafish
D000900:Anti-Bacterial Agents; D002352:Carrier Proteins; D016207:Cytokines; D029721:Drosophila Proteins; D008051:Lipid Bilayers; C066254:MDK protein, human; C514348:Miple2 protein, Drosophila; D009414:Nerve Growth Factors; C066845:pleiotrophin; D000078792:Midkine