Discovery of fragment molecules that bind the human peroxiredoxin 5 active site.
Barelier
Sarah
S
Laboratory of Analytical Sciences (UMR CNRS 5180), Université Claude Bernard-Lyon 1, Bât. ESCPE Lyon, Domaine scientifique de la Doua, Villeurbanne, France.
Linard
Dominique
D
Pons
Julien
J
Clippe
André
A
Knoops
Bernard
B
Lancelin
Jean-Marc
JM
Krimm
Isabelle
I
D001665:Binding Sites; D020134:Catalytic Domain; D018360:Crystallography, X-Ray / Q000379:methods; D003545:Cysteine / Q000737:chemistry; D006801:Humans; D007700:Kinetics; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008956:Models, Chemical; D008958:Models, Molecular; D010544:Peroxidases / Q000737:chemistry; D054464:Peroxiredoxins / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation
D008024:Ligands; D010544:Peroxidases; D054464:Peroxiredoxins; D003545:Cysteine