Tumor-infiltrating lymphocytes, particularly the balance between CD8(+) T cells and CCR4(+) regulatory T cells, affect the survival of patients with oral squamous cell carcinoma.
Watanabe
Yoshiko
Y
Department of Oral and Maxillofacial Surgery, Hamamatsu University, Hamamatsu, Japan.
Katou
Fuminori
F
Ohtani
Haruo
H
Nakayama
Takashi
T
Yoshie
Osamu
O
Hashimoto
Kenji
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D051858:Forkhead Transcription Factors / Q000032:analysis; D005887:Gingival Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery; D006801:Humans; D016130:Immunophenotyping; D018655:Lymphocyte Count; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D011379:Prognosis; D054398:Receptors, CCR4 / Q000276:immunology*; D012189:Retrospective Studies; D015996:Survival Rate; D016176:T-Lymphocyte Subsets / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014062:Tongue Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery
C418974:FOXP3 protein, human; D051858:Forkhead Transcription Factors; D054398:Receptors, CCR4