Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells.
Fuhler
Gwenny M
GM
Department of Gasteroenterology and Hepatology, Erasmus University Medical Center Rotterdam, The Netherlands. g.fuhler@erasmusmc.nl <g.fuhler@erasmusmc.nl>
Baanstra
Mirjam
M
Chesik
Daniel
D
Somasundaram
Rajesh
R
Seckinger
Anja
A
Hose
Dirk
D
Peppelenbosch
Maikel P
MP
Bos
Nico A
NA
D001854:Bone Marrow Cells / Q000473:pathology* / Q000502:physiology*; D002453:Cell Cycle; D002454:Cell Differentiation; D002460:Cell Line; D045744:Cell Line, Tumor; D018920:Coculture Techniques; D019008:Drug Resistance, Neoplasm; D006801:Humans; D009101:Multiple Myeloma / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology*; D014411:Neoplastic Stem Cells / Q000473:pathology / Q000502:physiology; D010770:Phosphotransferases / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D012008:Recurrence; D015398:Signal Transduction; D017154:Stromal Cells / Q000473:pathology / Q000502:physiology; D053668:Syndecan-1 / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism; D020741:rho GTP-Binding Proteins / Q000378:metabolism
D012333:RNA, Messenger; D012334:RNA, Neoplasm; C508241:SDC1 protein, human; D053668:Syndecan-1; D014157:Transcription Factors; D010770:Phosphotransferases; D020741:rho GTP-Binding Proteins