title: Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial.
authors.affiliation: Division of Child Health, University of Nottingham, Nottingham, UK. alan.smyth@nottingham.ac.uk
authors.forename: Alan R
authors.initials: AR
authors.lastname: Smyth
authors.forename: Paramita M
authors.initials: PM
authors.lastname: Cifelli
authors.forename: Catharine A
authors.initials: CA
authors.lastname: Ortori
authors.forename: Karima
authors.initials: K
authors.lastname: Righetti
authors.forename: Sarah
authors.initials: S
authors.lastname: Lewis
authors.forename: Penny
authors.initials: P
authors.lastname: Erskine
authors.forename: Elaine D
authors.initials: ED
authors.lastname: Holland
authors.forename: Michael
authors.initials: M
authors.lastname: Givskov
authors.forename: Paul
authors.initials: P
authors.lastname: Williams
authors.forename: Miguel
authors.initials: M
authors.lastname: Cámara
authors.forename: David A
authors.initials: DA
authors.lastname: Barrett
authors.forename: Alan
authors.initials: A
authors.lastname: Knox
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000032:analysis; D000293:Adolescent; D000328:Adult; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005737:Garlic; D006714:Homoserine / Q000031:analogs & derivatives / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods*; D010865:Pilot Projects; D010938:Plant Oils / Q000627:therapeutic use*; D010949:Plasma / Q000737:chemistry; D011552:Pseudomonas Infections / Q000150:complications* / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D053038:Quorum Sensing / Q000187:drug effects*; D012129:Respiratory Function Tests; D013183:Sputum / Q000737:chemistry; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: C109860:N-(3-oxododecanoyl)homoserine lactone; C092312:N-butyrylhomoserine lactone; D010938:Plant Oils; D006714:Homoserine; D015107:4-Butyrolactone