Reactive oxygen species promote caspase-12 expression and tubular apoptosis in diabetic nephropathy.
Brezniceanu
Marie-Luise
ML
Université de Montréal, Centre de recherche du Centre hospitalier de l'Université de Montréal, Hôtel-Dieu Hospital, Pavillon Masson, 3850 Saint Urbain Street, Montréal, Québec, Canada H2W 1T8.
Lau
Cara J
CJ
Godin
Nicolas
N
Chénier
Isabelle
I
Duclos
Alain
A
Ethier
Jean
J
Filep
Janos G
JG
Ingelfinger
Julie R
JR
Zhang
Shao-Ling
SL
Chan
John S D
JS
D000418:Albumins / Q000494:pharmacology; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D053454:Caspase 12 / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D003928:Diabetic Nephropathies / Q000378:metabolism* / Q000473:pathology*; D004195:Disease Models, Animal; D004721:Endoplasmic Reticulum / Q000502:physiology; D000091342:Endoplasmic Reticulum Chaperone BiP; D005786:Gene Expression Regulation / Q000187:drug effects; D006360:Heat-Shock Proteins / Q000378:metabolism; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D034741:RNA, Small Interfering / Q000494:pharmacology; D017382:Reactive Oxygen Species / Q000378:metabolism*; D051742:Transcription Factor CHOP / Q000378:metabolism
D000418:Albumins; C497250:Ddit3 protein, mouse; D000091342:Endoplasmic Reticulum Chaperone BiP; D006360:Heat-Shock Proteins; D034741:RNA, Small Interfering; D017382:Reactive Oxygen Species; D051742:Transcription Factor CHOP; D053454:Caspase 12