title: Disruption of neuronal function by soluble hyperphosphorylated tau in a Drosophila model of tauopathy.
authors.affiliation: School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK. C.M.Cowan@soton.ac.uk
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Cowan
authors.forename: Francis
authors.initials: F
authors.lastname: Chee
authors.forename: David
authors.initials: D
authors.lastname: Shepherd
authors.forename: Amritpal
authors.initials: A
authors.lastname: Mudher
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004330:Drosophila / Q000378:metabolism; D038362:Glycogen Synthase Kinase 3 / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D010766:Phosphorylation / Q000502:physiology; D012995:Solubility; D024801:Tauopathies / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D015854:Up-Regulation / Q000502:physiology; D016875:tau Proteins / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D016875:tau Proteins; D038362:Glycogen Synthase Kinase 3; C080888:tau-protein kinase