A unique interaction between alphaIIb and beta3 in the head region is essential for outside-in signaling-related functions of alphaIIbbeta3 integrin.
Hauschner
Hagit
H
Amalia Biron Research Institute of Thrombosis and Hemostasis, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Landau
Meytal
M
Seligsohn
Uri
U
Rosenberg
Nurit
N
D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D003018:Clot Retraction; D006224:Cricetinae; D017931:DNA Primers / Q000235:genetics; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D066298:In Vitro Techniques; D039564:Integrin alphaV / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D039661:Integrin beta3 / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D040201:Platelet Membrane Glycoprotein IIb / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D011485:Protein Binding; D054730:Protein Interaction Domains and Motifs; D055550:Protein Stability; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D014162:Transfection; D014841:von Willebrand Factor / Q000378:metabolism
D017931:DNA Primers; D039564:Integrin alphaV; D039661:Integrin beta3; D040201:Platelet Membrane Glycoprotein IIb; D011994:Recombinant Proteins; D014841:von Willebrand Factor; D005340:Fibrinogen