title: CASOP: a computational approach for strain optimization aiming at high productivity.
authors.affiliation: Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, D-39106 Magdeburg, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Hädicke
authors.forename: Steffen
authors.initials: S
authors.lastname: Klamt
mesh_terms: D000332:Aerobiosis; D000465:Algorithms; D000693:Anaerobiosis; D001709:Biotechnology / Q000379:methods*; D003067:Coenzymes / Q000378:metabolism; D003198:Computer Simulation; D004926:Escherichia coli / Q000378:metabolism; D055785:Gene Knockdown Techniques; D005818:Genetic Engineering / Q000379:methods; D053858:Metabolic Networks and Pathways / Q000502:physiology*; D019802:Succinic Acid / Q000378:metabolism; D049490:Systems Biology / Q000379:methods*
chemical_list: D003067:Coenzymes; D019802:Succinic Acid