title: Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity.
authors.affiliation: Department of Molecular and Integrative Physiology, The University of Michigan Medical School, Ann Arbor, Michigan 48109-5622, USA.
authors.forename: Lawrence S
authors.initials: LS
authors.lastname: Argetsinger
authors.forename: Jeanne A
authors.initials: JA
authors.lastname: Stuckey
authors.forename: Scott A
authors.initials: SA
authors.lastname: Robertson
authors.forename: Rositsa I
authors.initials: RI
authors.lastname: Koleva
authors.forename: Joel M
authors.initials: JM
authors.lastname: Cline
authors.forename: Jarrod A
authors.initials: JA
authors.lastname: Marto
authors.forename: Martin G
authors.initials: MG
authors.lastname: Myers
authors.forename: Christin
authors.initials: C
authors.lastname: Carter-Su
mesh_terms: D000818:Animals; D015153:Blotting, Western; D002460:Cell Line; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D047468:Immunoprecipitation; D053614:Janus Kinase 2 / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D016297:Mutagenesis, Site-Directed; D010748:Phosphopeptides / Q000737:chemistry / Q000378:metabolism; D010766:Phosphorylation; D011485:Protein Binding / Q000235:genetics / Q000502:physiology; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary / Q000235:genetics / Q000502:physiology; D051381:Rats; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D013329:Structure-Activity Relationship; D053719:Tandem Mass Spectrometry; D014443:Tyrosine / Q000737:chemistry / Q000378:metabolism*
chemical_list: D010748:Phosphopeptides; D014443:Tyrosine; D013006:Growth Hormone; D053614:Janus Kinase 2