Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-kappaB in cultured lung epithelial cells.
Mizutani
Ayako
A
Department of Biochemistry, School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan.
Maeda
Noriko
N
Toku
Seikichi
S
Isohama
Yoichiro
Y
Sugahara
Kazuhiro
K
Yamamoto
Hideyuki
H
D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004847:Epithelial Cells / Q000187:drug effects* / Q000378:metabolism; D017930:Genes, Reporter; D006801:Humans; D020672:I-kappa B Proteins / Q000378:metabolism; D015151:Immunoblotting; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000187:drug effects* / Q000378:metabolism; D010766:Phosphorylation; D021381:Protein Transport; D011650:Pulmonary Alveoli / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D011773:Pyruvates / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D051996:Transcription Factor RelA / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D020672:I-kappa B Proteins; D016328:NF-kappa B; C000606204:NFKBIA protein, human; D011773:Pyruvates; D051996:Transcription Factor RelA; D014409:Tumor Necrosis Factor-alpha; C046522:ethyl pyruvate; D000072000:NF-KappaB Inhibitor alpha