Trichoplusia ni cells (High Five) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines.
Krammer
Florian
F
Vienna Institute of BioTechnology, Department of Biotechnology, University of Natural Resources and Applied Life Sciences, 1190 Vienna, Austria.
Schinko
Theresa
T
Palmberger
Dieter
D
Tauer
Christopher
C
Messner
Paul
P
Grabherr
Reingard
R
D000818:Animals; D000914:Antibodies, Viral / Q000378:metabolism; D016367:Baculoviridae / Q000235:genetics; D015153:Blotting, Western; D002460:Cell Line; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000096:biosynthesis* / Q000276:immunology; D009980:Influenza A virus / Q000254:growth & development* / Q000276:immunology; D007252:Influenza Vaccines / Q000096:biosynthesis* / Q000276:immunology; D051379:Mice; D046529:Microscopy, Electron, Transmission; D018411:Spodoptera / Q000166:cytology* / Q000821:virology; D014763:Viral Matrix Proteins / Q000096:biosynthesis* / Q000276:immunology; D014771:Virion / Q000302:isolation & purification* / Q000378:metabolism
D000914:Antibodies, Viral; C543345:H1N1 virus hemagglutinin; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D007252:Influenza Vaccines; C488936:M1 protein, Influenza A virus; D014763:Viral Matrix Proteins