Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV.
Feng
Xiao-Qing
XQ
Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China.
Zeng
Zhao-Sen
ZS
Liang
Yong-Hong
YH
Chen
Fen-Er
FE
Pannecouque
Christophe
C
Balzarini
Jan
J
De Clercq
Erik
E
D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D002460:Cell Line / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology*; D015498:HIV-2 / Q000187:drug effects; D006801:Humans; D007202:Indicators and Reagents; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D019380:Anti-HIV Agents; D007202:Indicators and Reagents; D011743:Pyrimidines; D018894:Reverse Transcriptase Inhibitors