Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies.
Stringaris
Kate
K
Hematology Branch National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Adams
Sharon
S
Uribe
Marcela
M
Eniafe
Rhoda
R
Wu
Colin O
CO
Savani
Bipin N
BN
Barrett
A John
AJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D015331:Cohort Studies; D005260:Female; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D019337:Hematologic Neoplasms / Q000235:genetics* / Q000276:immunology / Q000628:therapy*; D006650:Histocompatibility Testing; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000276:immunology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D054340:Receptors, KIR / Q000235:genetics*; D012307:Risk Factors; D035781:Siblings; D033581:Stem Cell Transplantation / Q000379:methods*; D014019:Tissue Donors; D016896:Treatment Outcome; D055815:Young Adult
D006680:HLA Antigens; D054340:Receptors, KIR