Mutagenesis studies of neuropeptide S identify a suitable peptide tracer for neuropeptide S receptor binding studies and peptides selectively activating the I(107) variant of human neuropeptide S receptor.
Nepomuceno
Diane
D
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., San Diego, CA 92121, USA. dnepomuc@its.jnj.com
Sutton
Steve
S
Yu
Jingxue
J
Zhu
Jessica
J
Liu
Changlu
C
Lovenberg
Timothy
T
Bonaventure
Pascal
P
D000595:Amino Acid Sequence; D000818:Animals; D001120:Arginine; D002118:Calcium / Q000378:metabolism; D002460:Cell Line; D006801:Humans; D007532:Isoleucine; D008969:Molecular Sequence Data; D016296:Mutagenesis; D009154:Mutation; D009479:Neuropeptides / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D011485:Protein Binding; D011849:Radioactive Tracers; D051381:Rats; D018013:Receptors, Neuropeptide / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D009479:Neuropeptides; D011849:Radioactive Tracers; D018013:Receptors, Neuropeptide; C506531:neuropeptide S, human; D007532:Isoleucine; D001120:Arginine; D002118:Calcium