Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo.
Luheshi
Leila M
LM
Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.
Hoyer
Wolfgang
W
de Barros
Teresa Pereira
TP
van Dijk Härd
Iris
I
Brorsson
Ann-Christin
AC
Macao
Bertil
B
Persson
Cecilia
C
Crowther
Damian C
DC
Lomas
David A
DA
Ståhl
Stefan
S
Dobson
Christopher M
CM
Härd
Torleif
T
D000682:Amyloid / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000235:genetics / Q000378:metabolism / Q000633:toxicity; D000818:Animals; D030801:Animals, Genetically Modified; D001921:Brain / Q000378:metabolism; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D010446:Peptide Fragments / Q000235:genetics / Q000378:metabolism / Q000633:toxicity; D017956:Photoreceptor Cells, Invertebrate / Q000378:metabolism / Q000648:ultrastructure; D011485:Protein Binding; D011487:Protein Conformation; D015996:Survival Rate
D000682:Amyloid; D016229:Amyloid beta-Peptides; D010446:Peptide Fragments