Genipin protects lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice.
Kim
Seok-Joo
SJ
College of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Kim
Joon-Ki
JK
Lee
Dong-Ung
DU
Kwak
Jong-Hwan
JH
Lee
Sun-Mee
SM
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D020169:Caspases / Q000378:metabolism; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism; D045304:Cytochromes c / Q000378:metabolism; D003600:Cytosol / Q000187:drug effects / Q000378:metabolism; D005688:Galactosamine / Q000494:pharmacology*; D005786:Gene Expression Regulation / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D020672:I-kappa B Proteins / Q000378:metabolism; D057889:Iridoid Glycosides; D039823:Iridoids / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology*; D017114:Liver Failure, Acute / Q000097:blood / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D000072000:NF-KappaB Inhibitor alpha; D018384:Oxidative Stress / Q000187:drug effects; D010766:Phosphorylation / Q000187:drug effects; D021381:Protein Transport / Q000187:drug effects; D016755:Proto-Oncogene Proteins c-jun / Q000378:metabolism; D053199:TNF Receptor-Associated Death Domain Protein / Q000378:metabolism; D000637:Transaminases / Q000097:blood; D051996:Transcription Factor RelA / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D020672:I-kappa B Proteins; D057889:Iridoid Glycosides; D039823:Iridoids; D008070:Lipopolysaccharides; C000606205:Nfkbia protein, mouse; D016755:Proto-Oncogene Proteins c-jun; D053199:TNF Receptor-Associated Death Domain Protein; D051996:Transcription Factor RelA; D014409:Tumor Necrosis Factor-alpha; D000072000:NF-KappaB Inhibitor alpha; D005688:Galactosamine; D045304:Cytochromes c; C007834:genipin; D000637:Transaminases; D020169:Caspases; D005978:Glutathione