title: Crystal structures of the CBS and DRTGG domains of the regulatory region of Clostridiumperfringens pyrophosphatase complexed with the inhibitor, AMP, and activator, diadenosine tetraphosphate.
authors.affiliation: Department of Biochemistry and Food Chemistry, University of Turku, Vatselankatu 2, FI-20014 Turku, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Tuominen
authors.forename: A
authors.initials: A
authors.lastname: Salminen
authors.forename: E
authors.initials: E
authors.lastname: Oksanen
authors.forename: J
authors.initials: J
authors.lastname: Jämsen
authors.forename: O
authors.initials: O
authors.lastname: Heikkilä
authors.forename: L
authors.initials: L
authors.lastname: Lehtiö
authors.forename: N N
authors.initials: NN
authors.lastname: Magretova
authors.forename: A
authors.initials: A
authors.lastname: Goldman
authors.forename: A A
authors.initials: AA
authors.lastname: Baykov
authors.forename: R
authors.initials: R
authors.lastname: Lahti
mesh_terms: D000249:Adenosine Monophosphate / Q000737:chemistry / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism*; D003016:Clostridium perfringens / Q000201:enzymology*; D018360:Crystallography, X-Ray; D019281:Dimerization; D015226:Dinucleoside Phosphates / Q000737:chemistry / Q000378:metabolism; D020536:Enzyme Activators / Q000737:chemistry / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D011755:Pyrophosphatases / Q000737:chemistry* / Q000378:metabolism*; D016415:Sequence Alignment
chemical_list: D001426:Bacterial Proteins; D015226:Dinucleoside Phosphates; D020536:Enzyme Activators; D004791:Enzyme Inhibitors; D000249:Adenosine Monophosphate; C020733:diadenosine tetraphosphate; D011755:Pyrophosphatases