Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.
Pistollato
Francesca
F
Hemato-Oncology Laboratory, Department of Pediatrics, University of Padova, 3-35128 Padova, Italy. francesca.pistollato@unipd.it
Abbadi
Sara
S
Rampazzo
Elena
E
Persano
Luca
L
Della Puppa
Alessandro
A
Frasson
Chiara
C
Sarto
Eva
E
Scienza
Renato
R
D'avella
Domenico
D
Basso
Giuseppe
G
D000071916:AC133 Antigen; D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D001932:Brain Neoplasms / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology*; D054337:Cell Dedifferentiation / Q000502:physiology; D015254:DNA Modification Methylases / Q000096:biosynthesis* / Q000235:genetics; D045643:DNA Repair Enzymes / Q000096:biosynthesis* / Q000235:genetics; D005909:Glioblastoma / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology*; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D000860:Hypoxia / Q000201:enzymology / Q000473:pathology*; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014411:Neoplastic Stem Cells / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D019635:Neurosurgical Procedures; D010455:Peptides / Q000378:metabolism; D014407:Tumor Cells, Cultured; D025521:Tumor Suppressor Proteins / Q000096:biosynthesis* / Q000235:genetics
D000071916:AC133 Antigen; D015703:Antigens, CD; D006023:Glycoproteins; C000606023:PROM1 protein, human; D010455:Peptides; D025521:Tumor Suppressor Proteins; D015254:DNA Modification Methylases; C515491:MGMT protein, human; D045643:DNA Repair Enzymes