Intraarticular gene transfer of thrombospondin-1 suppresses the disease progression of experimental osteoarthritis.
Hsieh
Jeng-Long
JL
Department of Nursing, Chung Hwa University of Medical Technology, Tainan Hsien, Taiwan.
Shen
Po-Chuan
PC
Shiau
Ai-Li
AL
Jou
I-Ming
IM
Lee
Che-Hsin
CH
Wang
Chrong-Reen
CR
Teo
Min-Li
ML
Wu
Chao-Liang
CL
D000256:Adenoviridae / Q000235:genetics; D000818:Animals; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D004195:Disease Models, Animal; D018450:Disease Progression; D018014:Gene Transfer Techniques; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology; D007270:Injections, Intra-Articular; D053583:Interleukin-1beta / Q000378:metabolism; D007596:Joints / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D009389:Neovascularization, Pathologic / Q000378:metabolism / Q000503:physiopathology; D010003:Osteoarthritis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D011859:Radiography; D051381:Rats; D017208:Rats, Wistar; D019700:Thrombospondin 1 / Q000008:administration & dosage / Q000235:genetics* / Q000627:therapeutic use*; D016212:Transforming Growth Factor beta / Q000378:metabolism; D016896:Treatment Outcome
D053583:Interleukin-1beta; D019700:Thrombospondin 1; D016212:Transforming Growth Factor beta