Gemcitabine induces the VMP1-mediated autophagy pathway to promote apoptotic death in human pancreatic cancer cells.
Pardo
Romina
R
Department of Physiology, University of Buenos Aires, Buenos Aires, Argentina.
Lo Ré
Andrea
A
Archange
Cendrine
C
Ropolo
Alejandro
A
Papademetrio
Daniela L
DL
Gonzalez
Claudio D
CD
Alvarez
Elida M
EM
Iovanna
Juan L
JL
Vaccaro
Maria I
MI
D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D001343:Autophagy / Q000187:drug effects*; D053148:Caspase 3 / Q000378:metabolism; D045744:Cell Line, Tumor; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D055785:Gene Knockdown Techniques; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology*; D014617:Vacuoles / Q000378:metabolism; D000093542:Gemcitabine
D008565:Membrane Proteins; C526584:VMP1 protein, human; D003841:Deoxycytidine; C025946:3-methyladenine; D053148:Caspase 3; D000225:Adenine; D000093542:Gemcitabine