title: KMUP-1 ameliorates monocrotaline-induced pulmonary arterial hypertension through the modulation of Ca2+ sensitization and K+-channel.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Division of Pediatric Pulmonology and Cardiology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
authors.forename: Zen-Kong
authors.initials: ZK
authors.lastname: Dai
authors.forename: Yung-Jen
authors.initials: YJ
authors.lastname: Cheng
authors.forename: Hui-Hsuan
authors.initials: HH
authors.lastname: Chung
authors.forename: Jiunn-Ren
authors.initials: JR
authors.lastname: Wu
authors.forename: Ing-Jun
authors.initials: IJ
authors.lastname: Chen
authors.forename: Bin-Nan
authors.initials: BN
authors.lastname: Wu
mesh_terms: D000818:Animals; D015153:Blotting, Western; D002118:Calcium / Q000378:metabolism*; D002908:Chronic Disease; D005260:Female; D006976:Hypertension, Pulmonary / Q000517:prevention & control*; D016686:Monocrotaline; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D009213:Myography; D010880:Piperidines / Q000494:pharmacology*; D024681:Potassium Channels, Calcium-Activated / Q000187:drug effects / Q000235:genetics; D024642:Potassium Channels, Voltage-Gated / Q000187:drug effects / Q000378:metabolism; D011651:Pulmonary Artery / Q000187:drug effects* / Q000503:physiopathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D015854:Up-Regulation / Q000187:drug effects; D014970:Xanthines / Q000494:pharmacology*; D054460:rho-Associated Kinases / Q000378:metabolism; D020742:rhoA GTP-Binding Protein / Q000378:metabolism
chemical_list: D010880:Piperidines; D024681:Potassium Channels, Calcium-Activated; D024642:Potassium Channels, Voltage-Gated; D014970:Xanthines; C439304:KMUP 1; D016686:Monocrotaline; D054460:rho-Associated Kinases; D020742:rhoA GTP-Binding Protein; D002118:Calcium