The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation.
Thompson
John S
JS
The Veterans Affairs Medical Center. jsthom1@uky.edu
Chu
Yanxia
Y
Glass
Judith
J
Tapp
Andrea A
AA
Brown
Stephen A
SA
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects / Q000528:radiation effects; D040761:Biomimetic Materials / Q000494:pharmacology*; D004307:Dose-Response Relationship, Radiation; D006413:Hematopoietic System / Q000187:drug effects* / Q000473:pathology / Q000528:radiation effects; D008221:Lymphoid Tissue / Q000187:drug effects* / Q000473:pathology / Q000528:radiation effects; D008297:Male; D008345:Manganese; D051379:Mice; D008807:Mice, Inbred BALB C; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects / Q000528:radiation effects; D011837:Radiation-Protective Agents / Q000737:chemistry / Q000494:pharmacology*; D013482:Superoxide Dismutase; D015996:Survival Rate; D014916:Whole-Body Irradiation
D000975:Antioxidants; D009942:Organometallic Compounds; D011837:Radiation-Protective Agents; C121876:imisopasem manganese; D008345:Manganese; D013482:Superoxide Dismutase