Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells.
Lu
Ling
L
Division of Rheumatology, Department of Medicine, Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Wang
Julie
J
Zhang
Feng
F
Chai
Yang
Y
Brand
David
D
Wang
Xuehao
X
Horwitz
David A
DA
Shi
Wei
W
Zheng
Song Guo
SG
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects / Q000235:genetics / Q000276:immunology*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D051858:Forkhead Transcription Factors / Q000096:biosynthesis; D055879:Gene Knock-In Techniques; D006877:Hydroxamic Acids / Q000494:pharmacology; D020381:Interleukin-17 / Q000096:biosynthesis*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008822:Mice, Transgenic; D018125:Receptors, Transforming Growth Factor beta / Q000502:physiology; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics / Q000276:immunology*; D051899:Smad2 Protein / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D051900:Smad3 Protein / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D006377:T-Lymphocytes, Helper-Inducer / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology* / Q000378:metabolism; D016212:Transforming Growth Factor beta / Q000502:physiology
D051858:Forkhead Transcription Factors; C498833:Foxp3 protein, mouse; D006877:Hydroxamic Acids; D020381:Interleukin-17; D018125:Receptors, Transforming Growth Factor beta; D051899:Smad2 Protein; C497783:Smad2 protein, mouse; D051900:Smad3 Protein; C497791:Smad3 protein, mouse; D016212:Transforming Growth Factor beta; C012589:trichostatin A