Kupffer cell depletion reduces hepatic inflammation and apoptosis but decreases survival in abdominal sepsis.
Traeger
Tobias
T
Department of Surgery, Ernst-Moritz-Arndt-Universität, Greifswald, Germany. traeger@uni-greifswald.de
Mikulcak
Marlene
M
Eipel
Christian
C
Abshagen
Kerstin
K
Diedrich
Stephan
S
Heidecke
Claus-Dieter
CD
Maier
Stefan
S
Vollmar
Brigitte
B
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000276:immunology; D004002:Clodronic Acid / Q000494:pharmacology*; D003106:Colon; D016207:Cytokines / Q000097:blood; D004195:Disease Models, Animal; D005260:Female; D006505:Hepatitis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D007728:Kupffer Cells / Q000187:drug effects* / Q000473:pathology*; D008081:Liposomes / Q000494:pharmacology*; D008099:Liver / Q000098:blood supply / Q000276:immunology / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D008833:Microcirculation / Q000276:immunology; D010538:Peritonitis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D018805:Sepsis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D015607:Stents; D015996:Survival Rate
D016207:Cytokines; D008081:Liposomes; D004002:Clodronic Acid