Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of ¹³¹I by carbamazepine in breast cancer cells.
Willhauck
Michael J
MJ
Department of Internal Medicine II, Ludwig-Maximilians-University, Klinikum Grosshadern, Marchioninistrasse 15, 81377, Muenchen, Germany.
O Kane
Dennis J
DJ
Wunderlich
Nathalie
N
Göke
Burkhard
B
Spitzweg
Christine
C
D015153:Blotting, Western; D001943:Breast Neoplasms / Q000235:genetics / Q000378:metabolism*; D002220:Carbamazepine / Q000494:pharmacology* / Q000627:therapeutic use; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003907:Dexamethasone / Q000494:pharmacology; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000494:pharmacology* / Q000627:therapeutic use; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D000081082:Phosphoinositide-3 Kinase Inhibitors; D016133:Polymerase Chain Reaction; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D047488:Retinoid X Receptors / Q000378:metabolism; D027981:Symporters / Q000235:genetics* / Q000378:metabolism*; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D014212:Tretinoin / Q000494:pharmacology*; D014410:Tumor Stem Cell Assay; D000099209:Sodium-Iodide Symporters
D002220:Carbamazepine; D003907:Dexamethasone; D007457:Iodine Radioisotopes; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D051057:Proto-Oncogene Proteins c-akt; D047488:Retinoid X Receptors; D027981:Symporters; D058570:TOR Serine-Threonine Kinases; D014212:Tretinoin; D000099209:Sodium-Iodide Symporters