title: Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B.
authors.affiliation: Department of Clinical Chemistry, Helsinki University Central Hospital, Haartmaninkatu, Helsinki, Finland. paivi.lakkisto@helsinki.fi
authors.forename: Päivi
authors.initials: P
authors.lastname: Lakkisto
authors.forename: Ville
authors.initials: V
authors.lastname: Kytö
authors.forename: Hanna
authors.initials: H
authors.lastname: Forsten
authors.forename: Juha-Matti
authors.initials: JM
authors.lastname: Siren
authors.forename: Heli
authors.initials: H
authors.lastname: Segersvärd
authors.forename: Liisa-Maria
authors.initials: LM
authors.lastname: Voipio-Pulkki
authors.forename: Mika
authors.initials: M
authors.lastname: Laine
authors.forename: Kari
authors.initials: K
authors.lastname: Pulkki
authors.forename: Ilkka
authors.initials: I
authors.lastname: Tikkanen
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002248:Carbon Monoxide / Q000378:metabolism*; D002263:Carboxyhemoglobin / Q000235:genetics / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D054377:Chemokine CXCL12 / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D005786:Gene Expression Regulation; D051547:Heme Oxygenase-1 / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000378:metabolism*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000473:pathology; D009203:Myocardial Infarction / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000473:pathology; D018919:Neovascularization, Physiologic / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013234:Stem Cells / Q000187:drug effects / Q000473:pathology; D013997:Time Factors; D042561:Vascular Endothelial Growth Factor B / Q000378:metabolism*
chemical_list: D054377:Chemokine CXCL12; C497444:Hif1a protein, rat; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D012333:RNA, Messenger; D042561:Vascular Endothelial Growth Factor B; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D051547:Heme Oxygenase-1; D019009:Proto-Oncogene Proteins c-kit