Aspartic acid racemization and collagen degradation markers reveal an accumulation of damage in tendon collagen that is enhanced with aging.
Thorpe
Chavaunne T
CT
Division of Surgery and Interventional Science, University College London, Institute of Orthopaedics and Musculoskeletal Science, Royal National Orthopaedic Hospital, London, UK. rejacth@ucl.ac.uk
Streeter
Ian
I
Pinchbeck
Gina L
GL
Goodship
Allen E
AE
Clegg
Peter D
PD
Birch
Helen L
HL
D000375:Aging / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D024042:Collagen Type I / Q000378:metabolism*; D005260:Female; D006736:Horses; D008297:Male; D013708:Tendon Injuries / Q000378:metabolism* / Q000473:pathology; D013710:Tendons / Q000378:metabolism* / Q000473:pathology
D015415:Biomarkers; D024042:Collagen Type I; D001224:Aspartic Acid