[Neurodegenerative polyglutamine expansion diseases: physiopathology and therapeutic strategies].
Ravache
M
M
Département de Neurobiologie et Génétique, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/Inserm, université de Strasbourg, BP 10142, 67404 Illkirch cedex, France.
Abou-Sleymane
G
G
Trottier
Y
Y
D000328:Adult; D017668:Age of Onset; D000818:Animals; D004195:Disease Models, Animal; D004331:Drosophila melanogaster / Q000235:genetics; D016332:Fetal Tissue Transplantation; D005786:Gene Expression Regulation / Q000235:genetics; D005799:Genes, Dominant; D020271:Heredodegenerative Disorders, Nervous System / Q000235:genetics* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D051379:Mice; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000378:metabolism; D009474:Neurons / Q000637:transplantation; D010455:Peptides / Q000235:genetics*; D011485:Protein Binding; D011499:Protein Processing, Post-Translational; D034622:RNA Interference; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic; D019680:Trinucleotide Repeat Expansion / Q000235:genetics*
D009419:Nerve Tissue Proteins; D010455:Peptides; D012333:RNA, Messenger; C097188:polyglutamine
Les maladies neurodégénératives par expansion de polyglutamine: physiopathologie et stratégies thérapeutiques.