title: A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.
authors.affiliation: Department of Pharmacology and Toxicology, University of Lausanne, 1005 Lausanne, Switzerland.
authors.forename: Luz Angélica
authors.initials: LA
authors.lastname: Liechti
authors.forename: Simon
authors.initials: S
authors.lastname: Bernèche
authors.forename: Benoîte
authors.initials: B
authors.lastname: Bargeton
authors.forename: Justyna
authors.initials: J
authors.lastname: Iwaszkiewicz
authors.forename: Sophie
authors.initials: S
authors.lastname: Roy
authors.forename: Olivier
authors.initials: O
authors.lastname: Michielin
authors.forename: Stephan
authors.initials: S
authors.lastname: Kellenberger
mesh_terms: D062565:Acid Sensing Ion Channels; D019943:Amino Acid Substitution; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015640:Ion Channel Gating / Q000502:physiology*; D008954:Models, Biological; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D020125:Mutation, Missense; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D015222:Sodium Channels / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
chemical_list: C568266:ASIC1 protein, human; D062565:Acid Sensing Ion Channels; D009419:Nerve Tissue Proteins; D015222:Sodium Channels