title: Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism.
authors.affiliation: Laboratory of Pharmacology and Toxicology, Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, Universidad de Chile, Santiago 8380492, Chile. mel@ciq.uchile.cl
authors.forename: María Eugenia
authors.initials: ME
authors.lastname: Letelier
authors.forename: José
authors.initials: J
authors.lastname: Jara-Sandoval
authors.forename: Alfredo
authors.initials: A
authors.lastname: Molina-Berríos
authors.forename: Mario
authors.initials: M
authors.lastname: Faúndez
authors.forename: Paula
authors.initials: P
authors.lastname: Aracena-Parks
authors.forename: Felipe
authors.initials: F
authors.lastname: Aguilera
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D016166:Free Radical Scavengers / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D008862:Microsomes, Liver / Q000201:enzymology; D010084:Oxidation-Reduction; D051381:Rats; D017207:Rats, Sprague-Dawley; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D017382:Reactive Oxygen Species; D003577:Cytochrome P-450 Enzyme System; D008550:Melatonin