title: Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol.
authors.affiliation: Departamento de Química Orgánica and UMYMFOR (CONICET-UBA), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina.
authors.forename: Evelyn L
authors.initials: EL
authors.lastname: Bonifazi
authors.forename: Carla
authors.initials: C
authors.lastname: Ríos-Luci
authors.forename: Leticia G
authors.initials: LG
authors.lastname: León
authors.forename: Gerardo
authors.initials: G
authors.lastname: Burton
authors.forename: José M
authors.initials: JM
authors.lastname: Padrón
authors.forename: Rosana I
authors.initials: RI
authors.lastname: Misico
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis* / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007202:Indicators and Reagents; D008055:Lipids / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009285:Naphthoquinones / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology*; D054876:Prenylation; D013329:Structure-Activity Relationship
chemical_list: C550391:5-hydroxylapachol; D000972:Antineoplastic Agents, Phytogenic; D007202:Indicators and Reagents; D008055:Lipids; D009285:Naphthoquinones; C008252:lapachol