title: Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.
authors.affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Charlene S L
authors.initials: CS
authors.lastname: Hoi
authors.forename: Song Eun
authors.initials: SE
authors.lastname: Lee
authors.forename: Shu-Yang
authors.initials: SY
authors.lastname: Lu
authors.forename: David J
authors.initials: DJ
authors.lastname: McDermitt
authors.forename: Karen M
authors.initials: KM
authors.lastname: Osorio
authors.forename: Caroline M
authors.initials: CM
authors.lastname: Piskun
authors.forename: Rachel M
authors.initials: RM
authors.lastname: Peters
authors.forename: Ralf
authors.initials: R
authors.lastname: Paus
authors.forename: Tudorita
authors.initials: T
authors.lastname: Tumbar
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002453:Cell Cycle / Q000502:physiology; D019070:Cell Lineage; D049109:Cell Proliferation; D002478:Cells, Cultured; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics / Q000378:metabolism*; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000235:genetics / Q000378:metabolism; D005260:Female; D018859:Hair Follicle / Q000166:cytology* / Q000502:physiology; D006801:Humans; D015603:Keratinocytes / Q000166:cytology / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009375:Neoplasms, Glandular and Epithelial / Q000378:metabolism* / Q000473:pathology; D010641:Phenotype; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012867:Skin / Q000166:cytology / Q000378:metabolism / Q000473:pathology*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*
chemical_list: D015415:Biomarkers; C493957:Cdkn1a protein, mouse; D050676:Core Binding Factor Alpha 2 Subunit; D050759:Cyclin-Dependent Kinase Inhibitor p21; D011993:Recombinant Fusion Proteins