Uncoupled responses of Smad4-deficient cancer cells to TNFalpha result in secretion of monomeric laminin-gamma2.
Zboralski
Dirk
D
Medizinische Universitätsklinik, Knappschaftskrankenhaus, IMBL, Ruhr-Universität Bochum, Bochum, Germany. Irmgard.Schwarte-Waldhoff@rub.de
Warscheid
Bettina
B
Klein-Scory
Susanne
S
Malas
M Bassel
MB
Becker
Heiko
H
Böckmann
Miriam
M
Meyer
Helmut E
HE
Schmiegel
Wolff
W
Simon-Assmann
Patricia
P
Schwarte-Waldhoff
Irmgard
I
D000236:Adenoma / Q000378:metabolism; D000595:Amino Acid Sequence; D015815:Cell Adhesion Molecules / Q000378:metabolism; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000502:physiology; D015179:Colorectal Neoplasms / Q000378:metabolism*; D004357:Drug Synergism; D055785:Gene Knockdown Techniques; D006801:Humans; D007797:Laminin / Q000737:chemistry / Q000378:metabolism*; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000378:metabolism; D011401:Promoter Regions, Genetic; D011487:Protein Conformation; D051901:Smad4 Protein / Q000172:deficiency* / Q000235:genetics / Q000378:metabolism; D016212:Transforming Growth Factor beta / Q000378:metabolism / Q000494:pharmacology; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D000097794:Kalinin
D015815:Cell Adhesion Molecules; D007797:Laminin; D016328:NF-kappa B; D051901:Smad4 Protein; D016212:Transforming Growth Factor beta; D014409:Tumor Necrosis Factor-alpha; D000097794:Kalinin; C400567:LAMC2 protein, human; C497796:SMAD4 protein, human; C095567:laminin alpha 3