The in vitro effects of Xancor, a synthetic astaxanthine derivative, on hemostatic biomarkers in aspirin-naïve and aspirin-treated subjects with multiple risk factors for vascular disease.
Serebruany
Victor
V
Heart Drug Research Laboratories, Johns Hopkins University Baltimore, MD, USA. Heartdrug@aol.com
Malinin
Alex
A
Goodin
Thomas
T
Pashkow
Fredric
F
D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology*; D015415:Biomarkers / Q000378:metabolism; D001777:Blood Coagulation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D011355:Prodrugs; D012307:Risk Factors; D016037:Single-Blind Method; D024341:Xanthophylls / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology*
D000975:Antioxidants; D015415:Biomarkers; D010975:Platelet Aggregation Inhibitors; D011355:Prodrugs; C550375:Xancor; D024341:Xanthophylls; C005948:astaxanthine; D001241:Aspirin