An active-site phenylalanine directs substrate binding and C-H cleavage in the alpha-ketoglutarate-dependent dioxygenase TauD.
McCusker
Kevin P
KP
Department of Chemistry, California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA.
Klinman
Judith P
JP
D002244:Carbon / Q000378:metabolism*; D020134:Catalytic Domain; D005296:Ferrous Compounds; D006859:Hydrogen / Q000378:metabolism*; D007700:Kinetics; D006899:Mixed Function Oxygenases / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D010649:Phenylalanine / Q000378:metabolism*; D013379:Substrate Specificity
D005296:Ferrous Compounds; D010649:Phenylalanine; D002244:Carbon; D006859:Hydrogen; D006899:Mixed Function Oxygenases; C433064:taurine-alpha-ketoglutarate dioxygenase