Synthesis and biological evaluation of antitumor-active gamma-butyrolactone substituted betulin derivatives.
Csuk
René
R
Bereich Organische Chemie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany. rene.csuk@chemie.uni-halle.de
Barthel
Alexander
A
Schwarz
Stefan
S
Kommera
Harish
H
Paschke
Reinhard
R
D015107:4-Butyrolactone / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D004396:Coloring Agents; D053938:DNA Fragmentation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D010084:Oxidation-Reduction; D012235:Rhodamines; D013237:Stereoisomerism; D014315:Triterpenes / Q000138:chemical synthesis* / Q000494:pharmacology*; D000094062:Betulinic Acid
D015107:4-Butyrolactone; D000970:Antineoplastic Agents; D004396:Coloring Agents; D012235:Rhodamines; D014315:Triterpenes; C022027:lissamine rhodamine B; C002503:betulin; D000094062:Betulinic Acid