title: Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants.
authors.affiliation: Department of Molecular Genetics and Microbiology, Box 3020, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: Joanne M
authors.initials: JM
authors.lastname: Kingsbury
authors.forename: John H
authors.initials: JH
authors.lastname: McCusker
mesh_terms: D002176:Candida albicans / Q000166:cytology / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D049109:Cell Proliferation / Q000187:drug effects; D003513:Cycloheximide / Q000494:pharmacology; D025461:Feedback, Physiological / Q000187:drug effects; D005656:Fungal Proteins / Q000378:metabolism; D016153:Genes, Suppressor; D006714:Homoserine / Q000633:toxicity*; D009154:Mutation / Q000235:genetics*; D010641:Phenotype; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000235:genetics* / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D014176:Protein Biosynthesis / Q000187:drug effects; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D012694:Serine / Q000031:analogs & derivatives; D013489:Suppression, Genetic / Q000187:drug effects; D013912:Threonine / Q000031:analogs & derivatives / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D005656:Fungal Proteins; D013912:Threonine; D012694:Serine; D006714:Homoserine; D003513:Cycloheximide; D017853:Phosphotransferases (Alcohol Group Acceptor); C021370:homoserine kinase; D046988:Proteasome Endopeptidase Complex