Comparison of the efficacy and impact on cognition of glycopyrrolate and biperiden for clozapine-induced sialorrhea in schizophrenic patients: a randomized, double-blind, crossover study.
Liang
Chih-Sung
CS
Department of Psychiatry, Beitou Armed Forces Hospital, 60 Shin-Ming Road, Beitou, Taipei, Taiwan.
Ho
Pei-Shen
PS
Shen
Lih-Jong
LJ
Lee
Wen-Kuei
WK
Yang
Fei-Wen
FW
Chiang
Kuo-Tung
KT
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001712:Biperiden / Q000009:adverse effects / Q000627:therapeutic use*; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D003071:Cognition / Q000187:drug effects*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006024:Glycopyrrolate / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008609:Mental Status Schedule; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D012798:Sialorrhea / Q000139:chemically induced* / Q000188:drug therapy*; D013624:Taiwan
D014150:Antipsychotic Agents; D018727:Muscarinic Antagonists; D001712:Biperiden; D003024:Clozapine; D006024:Glycopyrrolate