title: Ultrasound-guided intratumoral administration of collagenase-2 improved liposome drug accumulation in solid tumor xenografts.
authors.affiliation: Department of Radiology, Fudan University Huadong Hospital, 221 W. Yan'an Road, Shanghai 200040, China. zhengxp@fudan.edu.cn
authors.forename: Xiangpeng
authors.initials: X
authors.lastname: Zheng
authors.forename: Beth A
authors.initials: BA
authors.lastname: Goins
authors.forename: Ivan L
authors.initials: IL
authors.lastname: Cameron
authors.forename: Cristina
authors.initials: C
authors.lastname: Santoyo
authors.forename: Ande
authors.initials: A
authors.lastname: Bao
authors.forename: Victoria C
authors.initials: VC
authors.lastname: Frohlich
authors.forename: Gary D
authors.initials: GD
authors.lastname: Fullerton
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001345:Autoradiography; D004305:Dose-Response Relationship, Drug; D004317:Doxorubicin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D045604:Extracellular Fluid / Q000187:drug effects* / Q000378:metabolism; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000662:veterinary; D008081:Liposomes; D020784:Matrix Metalloproteinase 8 / Q000008:administration & dosage / Q000494:pharmacology*; D011877:Radionuclide Imaging / Q000379:methods; D019275:Radiopharmaceuticals / Q000737:chemistry; D051381:Rats; D011923:Rats, Nude; D013670:Sodium Pertechnetate Tc 99m / Q000737:chemistry; D015899:Tomography, Emission-Computed, Single-Photon; D018608:Ultrasonography, Doppler / Q000379:methods; D023041:Xenograft Model Antitumor Assays
chemical_list: D000903:Antibiotics, Antineoplastic; D008081:Liposomes; D019275:Radiopharmaceuticals; D004317:Doxorubicin; D013670:Sodium Pertechnetate Tc 99m; D020784:Matrix Metalloproteinase 8