Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An (18)F-DOPA and (11)C-DTBZ PET study.
Blesa
Javier
J
Movement Disorders Group, Neurosciences Division, CIMA, and Department of Neurology and Neurosurgery, Clínica Universidad de Navarra, Pamplona, Spain.
Juri
Carlos
C
Collantes
María
M
Peñuelas
Iván
I
Prieto
Elena
E
Iglesias
Elena
E
Martí-Climent
Josep
J
Arbizu
Javier
J
Zubieta
José L
JL
Rodríguez-Oroz
Mari Cruz
MC
García-García
David
D
Richter
José A
JA
Cavada
Carmen
C
Obeso
José A
JA
D000818:Animals; D001931:Brain Mapping; D002250:Carbon Radioisotopes; D002421:Caudate Nucleus / Q000000981:diagnostic imaging / Q000378:metabolism; D003342:Corpus Striatum / Q000000981:diagnostic imaging / Q000378:metabolism*; D004195:Disease Models, Animal; D018450:Disease Progression; D004298:Dopamine / Q000031:analogs & derivatives / Q000172:deficiency / Q000378:metabolism*; D020820:Dyskinesias / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D008252:Macaca fascicularis; D008297:Male; D020734:Parkinsonian Disorders / Q000000981:diagnostic imaging / Q000378:metabolism*; D049268:Positron-Emission Tomography / Q000379:methods; D011699:Putamen / Q000000981:diagnostic imaging / Q000378:metabolism; D012720:Severity of Illness Index; D012815:Signal Processing, Computer-Assisted; D013747:Tetrabenazine / Q000031:analogs & derivatives
D002250:Carbon Radioisotopes; C032811:dihydrotetrabenazine; C029253:6-fluorodopamine; D004298:Dopamine; D013747:Tetrabenazine