title: Should patients be screened for 12S rRNA mutations before treatment with aminoglycosides?
authors.affiliation: Division of Medical Genetics and the Saban Research Institute, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA. rboles@chla.usc.edu
authors.forename: Richard G
authors.initials: RG
authors.lastname: Boles
authors.forename: Philippe
authors.initials: P
authors.lastname: Friedlich
mesh_terms: D000617:Aminoglycosides / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005820:Genetic Testing; D034381:Hearing Loss / Q000139:chemically induced* / Q000235:genetics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D012313:RNA / Q000235:genetics*; D000077278:RNA, Mitochondrial; D012335:RNA, Ribosomal / Q000235:genetics*
chemical_list: D000617:Aminoglycosides; D000077278:RNA, Mitochondrial; D012335:RNA, Ribosomal; C075526:RNA, ribosomal, 12S; D012313:RNA