E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.
Yago
Tadayuki
T
Cardiovascular Biology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Shao
Bojing
B
Miner
Jonathan J
JJ
Yao
Longbiao
L
Klopocki
Arkadiusz G
AG
Maeda
Kenichiro
K
Coggeshall
K Mark
KM
McEver
Rodger P
RP
D000077329:Agammaglobulinaemia Tyrosine Kinase; D000818:Animals; D019040:E-Selectin / Q000502:physiology*; D006801:Humans; D018960:Hyaluronan Receptors / Q000235:genetics / Q000502:physiology*; D066298:In Vitro Techniques; D036904:Leukocyte Rolling / Q000502:physiology*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000502:physiology*; D008562:Membrane Glycoproteins / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D021962:Membrane Microdomains / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008822:Mice, Transgenic; D008954:Models, Biological; D009504:Neutrophils / Q000502:physiology; D019007:P-Selectin / Q000502:physiology; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D011505:Protein-Tyrosine Kinases / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000502:physiology; D051572:Proto-Oncogene Proteins c-hck / Q000502:physiology; D015398:Signal Transduction; D048051:p38 Mitogen-Activated Protein Kinases / Q000502:physiology; D019061:src-Family Kinases / Q000502:physiology
C476399:Cd44 protein, mouse; D019040:E-Selectin; D018960:Hyaluronan Receptors; D016169:Lymphocyte Function-Associated Antigen-1; D008562:Membrane Glycoproteins; D019007:P-Selectin; C084882:P-selectin ligand protein; D011518:Proto-Oncogene Proteins; D019869:Phosphatidylinositol 3-Kinases; D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase; C000625951:Btk protein, mouse; C496632:Hck protein, mouse; D051572:Proto-Oncogene Proteins c-hck; C060902:lyn protein-tyrosine kinase; C053102:proto-oncogene proteins c-fgr; D019061:src-Family Kinases; D048051:p38 Mitogen-Activated Protein Kinases