title: A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties.
authors.affiliation: Department of Molecular and Cellular Biochemistry and the Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America.
authors.forename: Eun Suk
authors.initials: ES
authors.lastname: Song
authors.forename: David W
authors.initials: DW
authors.lastname: Rodgers
authors.forename: Louis B
authors.initials: LB
authors.lastname: Hersh
mesh_terms: D000495:Allosteric Site; D016229:Amyloid beta-Peptides / Q000235:genetics; D000818:Animals; D019281:Dimerization; D015971:Gene Expression Regulation, Enzymologic; D007313:Insecta; D007339:Insulysin / Q000235:genetics*; D007700:Kinetics; D010455:Peptides / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D051381:Rats; D013379:Substrate Specificity; D001615:beta-Endorphin / Q000235:genetics
chemical_list: D016229:Amyloid beta-Peptides; D010455:Peptides; D010710:Phosphates; D001615:beta-Endorphin; D007339:Insulysin