title: Preclinical in vitro and in vivo characterization of the fully human monoclonal IgM antibody KBPA101 specific for Pseudomonas aeruginosa serotype IATS-O11.
authors.affiliation: Kenta Biotech AG, Rehhagstrasse 79, CH-3018 Bern, Switzerland. michael.rudolf@kentabiotech.com
authors.forename: Michael P
authors.initials: MP
authors.lastname: Horn
authors.forename: Adrian W
authors.initials: AW
authors.lastname: Zuercher
authors.forename: Martin A
authors.initials: MA
authors.lastname: Imboden
authors.forename: Michael P
authors.initials: MP
authors.lastname: Rudolf
authors.forename: Hedvika
authors.initials: H
authors.lastname: Lazar
authors.forename: Hong
authors.initials: H
authors.lastname: Wu
authors.forename: Niels
authors.initials: N
authors.lastname: Hoiby
authors.forename: Stefanie C
authors.initials: SC
authors.lastname: Fas
authors.forename: Alois B
authors.initials: AB
authors.lastname: Lang
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology* / Q000627:therapeutic use / Q000633:toxicity; D000911:Antibodies, Monoclonal / Q000276:immunology* / Q000627:therapeutic use / Q000633:toxicity; D000915:Antibody Affinity; D000918:Antibody Specificity; D001483:Base Sequence; D002460:Cell Line; D003165:Complement System Proteins / Q000378:metabolism; D017931:DNA Primers / Q000235:genetics; D004195:Disease Models, Animal; D018922:HL-60 Cells; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology* / Q000627:therapeutic use / Q000633:toxicity; D066298:In Vitro Techniques; D051379:Mice; D010587:Phagocytosis; D018410:Pneumonia, Bacterial / Q000276:immunology / Q000517:prevention & control; D011552:Pseudomonas Infections / Q000276:immunology / Q000517:prevention & control / Q000628:therapy; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000235:genetics / Q000276:immunology*; D011817:Rabbits; D018805:Sepsis / Q000276:immunology / Q000517:prevention & control / Q000628:therapy; D012703:Serotyping
chemical_list: D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D017931:DNA Primers; D007075:Immunoglobulin M; D003165:Complement System Proteins