Targeting a kinetochore-associated motor protein to kill cancer cells.
Wacker
Sarah A
SA
Laboratory of Chemistry and Cell Biology, The Rockefeller University, New York, NY 10065, USA.
Kapoor
Tarun M
TM
D000818:Animals; D050256:Antimitotic Agents / Q000737:chemistry / Q000494:pharmacology; D002868:Chromosomal Proteins, Non-Histone / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000502:physiology; D006801:Humans; D016547:Kinesins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000502:physiology; D018386:Kinetochores / Q000187:drug effects* / Q000502:physiology; D008938:Mitosis / Q000187:drug effects; D008958:Models, Molecular; D020409:Molecular Motor Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000502:physiology; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology
D050256:Antimitotic Agents; D002868:Chromosomal Proteins, Non-Histone; D020409:Molecular Motor Proteins; C068688:centromere protein E; D016547:Kinesins