IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.
Macey
Matthew R
MR
Virginia Commonwealth University, Biology Department, Box 842012, Richmond, VA 23284-2012, USA.
Sturgill
Jamie L
JL
Morales
Johanna K
JK
Falanga
Yves T
YT
Morales
Joshua
J
Norton
Sarah K
SK
Yerram
Nitin
N
Shim
Hoon
H
Fernando
Josephine
J
Gifillan
Alasdair M
AM
Gomez
Gregorio
G
Schwartz
Lawrence
L
Oskeritzian
Carole
C
Spiegel
Sarah
S
Conrad
Daniel
D
Ryan
John J
JJ
D000818:Animals; D002478:Cells, Cultured; D006706:Homeostasis / Q000276:immunology*; D006801:Humans; D015847:Interleukin-4 / Q000502:physiology*; D008407:Mast Cells / Q000276:immunology* / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000502:physiology; D000077293:Receptor, Transforming Growth Factor-beta Type I; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000502:physiology; D019948:Receptors, Interleukin-4 / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000502:physiology; D018125:Receptors, Transforming Growth Factor beta / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000502:physiology; D046509:Tissue Culture Techniques; D053773:Transforming Growth Factor beta1 / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000502:physiology*; D053662:Interleukin-4 Receptor alpha Subunit
D015847:Interleukin-4; D017346:Protein Serine-Threonine Kinases; D000077293:Receptor, Transforming Growth Factor-beta Type I; D011956:Receptors, Cell Surface; D019948:Receptors, Interleukin-4; D018125:Receptors, Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1; C504002:Il4ra protein, mouse; D053662:Interleukin-4 Receptor alpha Subunit