Pharmacokinetic analysis of topotecan after intra-vitreal injection. Implications for retinoblastoma treatment.
Buitrago
Emiliano
E
Department of Pharmacology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 5th floor, C1113AAD, Buenos Aires, Argentina.
Höcht
Christian
C
Chantada
Guillermo
G
Fandiño
Adriana
A
Navo
Elliot
E
Abramson
David H
DH
Schaiquevich
Paula
P
Bramuglia
Guillermo F
GF
D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D001082:Aqueous Humor / Q000378:metabolism*; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid; D007267:Injections; D011817:Rabbits; D019572:Retinal Neoplasms / Q000188:drug therapy*; D012175:Retinoblastoma / Q000188:drug therapy*; D019772:Topotecan / Q000493:pharmacokinetics* / Q000627:therapeutic use; D014822:Vitreous Body / Q000378:metabolism*
D000970:Antineoplastic Agents; D019772:Topotecan