title: The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.
authors.affiliation: Department of Medicine, University of Colorado Denver, 12700 E. 19th Avenue B-168, Aurora, CO 80045, USA.
authors.forename: Shay
authors.initials: S
authors.lastname: Matalon
authors.forename: Brent E
authors.initials: BE
authors.lastname: Palmer
authors.forename: Marcel F
authors.initials: MF
authors.lastname: Nold
authors.forename: Antonio
authors.initials: A
authors.lastname: Furlan
authors.forename: Afework
authors.initials: A
authors.lastname: Kassu
authors.forename: Gianluca
authors.initials: G
authors.lastname: Fossati
authors.forename: Paolo
authors.initials: P
authors.lastname: Mascagni
authors.forename: Charles A
authors.initials: CA
authors.lastname: Dinarello
mesh_terms: D065100:CCR5 Receptor Antagonists; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000821:virology*; D002460:Cell Line; D002478:Cells, Cultured; D016655:HIV Core Protein p24 / Q000096:biosynthesis; D015497:HIV-1 / Q000254:growth & development*; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology*; D006801:Humans; D006877:Hydroxamic Acids / Q000494:pharmacology*; D009000:Monocytes / Q000187:drug effects / Q000821:virology*; D019718:Receptors, CXCR4 / Q000037:antagonists & inhibitors*; D014635:Valproic Acid / Q000494:pharmacology
chemical_list: D065100:CCR5 Receptor Antagonists; C527276:CXCR4 protein, human; D016655:HIV Core Protein p24; D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D019718:Receptors, CXCR4; D014635:Valproic Acid; C502418:givinostat hydrochloride