Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels.
Mehta
Geeta
G
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Williams
Courtney M
CM
Alvarez
Luis
L
Lesniewski
Martha
M
Kamm
Roger D
RD
Griffith
Linda G
LG
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis*; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D066246:ErbB Receptors / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism; D022781:Hepatocytes / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D020100:Hydrogels / Q000737:chemistry* / Q000494:pharmacology; D047468:Immunoprecipitation; D008297:Male; D008856:Microscopy, Fluorescence; D010766:Phosphorylation / Q000187:drug effects; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics
D001672:Biocompatible Materials; D005353:Fibronectins; D020100:Hydrogels; D004815:Epidermal Growth Factor; D004247:DNA; C483803:Egfr protein, rat; D066246:ErbB Receptors