Lambda and alpha interferons inhibit hepatitis B virus replication through a common molecular mechanism but with different in vivo activities.
Pagliaccetti
Nicole E
NE
Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
Chu
Esther N
EN
Bolen
Christopher R
CR
Kleinstein
Steven H
SH
Robek
Michael D
MD
D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D016207:Cytokines / Q000276:immunology*; D020869:Gene Expression Profiling; D006515:Hepatitis B virus / Q000276:immunology* / Q000502:physiology; D022781:Hepatocytes / Q000821:virology; D006801:Humans; D016898:Interferon-alpha / Q000276:immunology*; D007378:Interleukins / Q000276:immunology*; D051379:Mice; D008822:Mice, Transgenic; D020411:Oligonucleotide Array Sequence Analysis; D014779:Virus Replication; D000095022:Interferon Lambda
D016207:Cytokines; D016898:Interferon-alpha; D007378:Interleukins; C000624353:interferon-lambda, human; D000095022:Interferon Lambda; C511668:interferon-lambda protein, mouse