Efficacy of a new sustained-release microsphere formulation of exenatide, DA-3091, in Zucker diabetic fatty (ZDF) rats.
Kwak
Hyun-Hee
HH
Biopharmaceutical Research Laboratory, Dong-A Pharm. Co. Ltd., Gyeonggi, 446-905, Republic of Korea.
Shim
Won-Sik
WS
Son
Mi-Kyung
MK
Kim
Yoon-Ji
YJ
Kim
Tae-Hyoung
TH
Youn
Hyun-Jun
HJ
Kang
Soo-Hyoung
SH
Shim
Chang-Koo
CK
D000818:Animals; D001786:Blood Glucose; D001835:Body Weight / Q000187:drug effects; D002626:Chemistry, Pharmaceutical; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D000077270:Exenatide; D005247:Feeding Behavior; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology; D008297:Male; D008863:Microspheres; D010455:Peptides / Q000008:administration & dosage* / Q000494:pharmacology*; D051381:Rats; D011924:Rats, Zucker; D014688:Venoms / Q000008:administration & dosage* / Q000494:pharmacology*
D001786:Blood Glucose; D000077270:Exenatide; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D010455:Peptides; D014688:Venoms