Crystal structures of the CBS and DRTGG domains of the regulatory region of Clostridiumperfringens pyrophosphatase complexed with the inhibitor, AMP, and activator, diadenosine tetraphosphate.
Tuominen
H
H
Department of Biochemistry and Food Chemistry, University of Turku, Vatselankatu 2, FI-20014 Turku, Finland.
Salminen
A
A
Oksanen
E
E
Jämsen
J
J
Heikkilä
O
O
Lehtiö
L
L
Magretova
N N
NN
Goldman
A
A
Baykov
A A
AA
Lahti
R
R
D000249:Adenosine Monophosphate / Q000737:chemistry / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism*; D003016:Clostridium perfringens / Q000201:enzymology*; D018360:Crystallography, X-Ray; D019281:Dimerization; D015226:Dinucleoside Phosphates / Q000737:chemistry / Q000378:metabolism; D020536:Enzyme Activators / Q000737:chemistry / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D011755:Pyrophosphatases / Q000737:chemistry* / Q000378:metabolism*; D016415:Sequence Alignment
D001426:Bacterial Proteins; D015226:Dinucleoside Phosphates; D020536:Enzyme Activators; D004791:Enzyme Inhibitors; D000249:Adenosine Monophosphate; C020733:diadenosine tetraphosphate; D011755:Pyrophosphatases