NGF-induced moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells.
Jeon
Songhee
S
Dongguk University Research Institute of Biotechnology, Seoul, Republic of Korea. jsong0304@dongguk.edu
Park
Jung-Keug
JK
Bae
Chang-Dae
CD
Park
Joobae
J
D000818:Animals; D002454:Cell Differentiation; D004789:Enzyme Activation; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D020932:Nerve Growth Factor / Q000494:pharmacology*; D016501:Neurites / Q000187:drug effects / Q000502:physiology*; D016716:PC12 Cells; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D010766:Phosphorylation / Q000187:drug effects; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects; D013379:Substrate Specificity; D013912:Threonine / Q000378:metabolism; D014162:Transfection; D020830:rac1 GTP-Binding Protein / Q000378:metabolism*
D008840:Microfilament Proteins; C071058:moesin; D013912:Threonine; D020932:Nerve Growth Factor; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt; D020830:rac1 GTP-Binding Protein