The protective effects of intratympanic dexamethasone and vitamin E on cisplatin-induced ototoxicity are demonstrated in rats.
Paksoy
Mustafa
M
2nd ENT Department, Kartal Training and Research Hospital, Istanbul, Turkey. opdrmustafapaksoy@yahoo.com
Ayduran
Emin
E
Sanlı
Arif
A
Eken
Mehmet
M
Aydın
Sedat
S
Oktay
Zeynep Alev
ZA
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002945:Cisplatin / Q000009:adverse effects; D003907:Dexamethasone / Q000008:administration & dosage*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects*; D005260:Female; D016166:Free Radical Scavengers / Q000008:administration & dosage; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced / Q000517:prevention & control*; D051381:Rats; D017208:Rats, Wistar; D014432:Tympanic Membrane / Q000187:drug effects; D014810:Vitamin E / Q000008:administration & dosage*
D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D016166:Free Radical Scavengers; D014810:Vitamin E; D003907:Dexamethasone; D002945:Cisplatin