title: Lipophilic cationic drugs increase the permeability of lysosomal membranes in a cell culture system.
authors.affiliation: Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany. johannes.kornhuber@uk-erlangen.de
authors.forename: Johannes
authors.initials: J
authors.lastname: Kornhuber
authors.forename: Andreas W
authors.initials: AW
authors.lastname: Henkel
authors.forename: Teja W
authors.initials: TW
authors.lastname: Groemer
authors.forename: Sven
authors.initials: S
authors.lastname: Städtler
authors.forename: Oliver
authors.initials: O
authors.lastname: Welzel
authors.forename: Philipp
authors.initials: P
authors.lastname: Tripal
authors.forename: Andrea
authors.initials: A
authors.lastname: Rotter
authors.forename: Stefan
authors.initials: S
authors.lastname: Bleich
authors.forename: Stefan
authors.initials: S
authors.lastname: Trapp
mesh_terms: D000547:Amantadine / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000588:Amines; D000639:Amitriptyline / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D002412:Cations; D045744:Cell Line, Tumor; D002936:Cinnarizine / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D003198:Computer Simulation; D025461:Feedback, Physiological; D005422:Flavoxate / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D005456:Fluorescent Dyes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008247:Lysosomes / Q000187:drug effects* / Q000378:metabolism; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D053141:Organelle Size; D010539:Permeability
chemical_list: D000588:Amines; D002412:Cations; D005456:Fluorescent Dyes; C493330:Red DND-99; D000639:Amitriptyline; D002936:Cinnarizine; D005422:Flavoxate; D000547:Amantadine