The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin.
Gupta
Radhika
R
Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Lavollay
Marie
M
Mainardi
Jean-Luc
JL
Arthur
Michel
M
Bishai
William R
WR
Lamichhane
Gyanu
G
D019881:Aminoacyltransferases / Q000502:physiology*; D000658:Amoxicillin / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008826:Microbial Sensitivity Tests; D008954:Models, Biological; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000201:enzymology* / Q000472:pathogenicity; D010403:Penicillin Resistance; D010457:Peptidoglycan / Q000378:metabolism; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
D000995:Antitubercular Agents; D010457:Peptidoglycan; D000658:Amoxicillin; D019881:Aminoacyltransferases; C022330:peptidoglycan transpeptidase