title: Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.
authors.affiliation: Wallenberg Laboratory, Institute of Medicine, Sahlgrenska University Hospital, S-41345 Gothenburg, Sweden.
authors.forename: Meng
authors.initials: M
authors.lastname: Liu
authors.forename: Anna-Karin M
authors.initials: AK
authors.lastname: Sjogren
authors.forename: Christin
authors.initials: C
authors.lastname: Karlsson
authors.forename: Mohamed X
authors.initials: MX
authors.lastname: Ibrahim
authors.forename: Karin M E
authors.initials: KM
authors.lastname: Andersson
authors.forename: Frida J
authors.initials: FJ
authors.lastname: Olofsson
authors.forename: Annika M
authors.initials: AM
authors.lastname: Wahlstrom
authors.forename: Martin
authors.initials: M
authors.lastname: Dalin
authors.forename: Huiming
authors.initials: H
authors.lastname: Yu
authors.forename: Zhenggang
authors.initials: Z
authors.lastname: Chen
authors.forename: Shao H
authors.initials: SH
authors.lastname: Yang
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Young
authors.forename: Martin O
authors.initials: MO
authors.lastname: Bergo
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000235:genetics / Q000378:metabolism; D000483:Alleles; D000818:Animals; D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000378:metabolism*; D004122:Dimethylallyltranstransferase / Q000172:deficiency / Q000378:metabolism*; D004195:Disease Models, Animal; D015971:Gene Expression Regulation, Enzymologic; D015972:Gene Expression Regulation, Neoplastic; D008175:Lung Neoplasms / Q000201:enzymology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics / Q000378:metabolism*
chemical_list: D019883:Alkyl and Aryl Transferases; C083291:geranylgeranyltransferase type-I; D004122:Dimethylallyltranstransferase; C495971:Hras protein, mouse; D016283:Proto-Oncogene Proteins p21(ras)