Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Hadden
Mark
M
AMRI, 26 Corporate Circle, Albany, NY 12212, USA. mark.hadden@amriglobal.com
Goodman
Allan
A
Guo
Cheng
C
Guzzo
Peter R
PR
Henderson
Alan J
AJ
Pattamana
Kevin
K
Ruenz
Megan
M
Sargent
Bruce J
BJ
Swenson
Brian
B
Yet
Larry
L
Liu
Jian
J
He
Shuwen
S
Sebhat
Iyassu K
IK
Lin
Linus S
LS
Tamvakopoulos
Constantin
C
Peng
Qianping
Q
Kan
Yanqing
Y
Palyha
Oksana
O
Kelly
Theresa M
TM
Guan
Xiao-Ming
XM
Metzger
Joseph M
JM
Reitman
Marc L
ML
Nargund
Ravi P
RP