Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo.
Kim
Kihyun
K
Department of Medical Oncology, The LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Kong
Sun-Young
SY
Fulciniti
Mariateresa
M
Li
Xianfeng
X
Song
Weihua
W
Nahar
Sabikun
S
Burger
Peter
P
Rumizen
Mathew J
MJ
Podar
Klaus
K
Chauhan
Dharminder
D
Hideshima
Teru
T
Munshi
Nikhil C
NC
Richardson
Paul
P
Clark
Ann
A
Ogden
Janet
J
Goutopoulos
Andreas
A
Rastelli
Luca
L
Anderson
Kenneth C
KC
Tai
Yu-Tzu
YT