title: Water equivalent thickness values of materials used in beams of protons, helium, carbon and iron ions.
abstract: Heavy charged particle beam radiotherapy for cancer is of increasing interest because it delivers a highly conformal radiation dose to the target volume. Accurate knowledge of the range of a heavy charged particle beam after it penetrates a patient's body or other materials in the beam line is very important and is usually stated in terms of the water equivalent thickness (WET). However, methods of calculating WET for heavy charged particle beams are lacking. Our objective was to test several simple analytical formulas previously developed for proton beams for their ability to calculate WET values for materials exposed to beams of protons, helium, carbon and iron ions. Experimentally measured heavy charged particle beam ranges and WET values from an iterative numerical method were compared with the WET values calculated by the analytical formulas. In most cases, the deviations were within 1 mm. We conclude that the analytical formulas originally developed for proton beams can also be used to calculate WET values for helium, carbon and iron ion beams with good accuracy.
authors.affiliation: Graduate School of Biomedical Sciences, The University of Texas at Houston, 6767 Bertner, Houston, TX 77030, USA.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Taddei
authors.forename: Markus M
authors.initials: MM
authors.lastname: Fitzek
authors.forename: Wayne D
authors.initials: WD
authors.lastname: Newhauser
mesh_terms: D002244:Carbon / Q000737:chemistry / Q000627:therapeutic use*; D006371:Helium / Q000737:chemistry / Q000627:therapeutic use*; D007501:Iron / Q000737:chemistry / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D017785:Photons / Q000627:therapeutic use*; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*; D035501:Uncertainty; D014867:Water
chemical_list: D014867:Water; D006371:Helium; D002244:Carbon; D007501:Iron