title: NO-Xplode: a case of supplement-associated ischemic colitis.
abstract: The most common cause of ischemic colitis (IC) is a sudden and transient reduction in splanchnic perfusion. In the younger population, medications are an increasingly recognized cause of ischemic bowel disease. Over-the-counter supplements may also lead to the development of ischemic colitis through similar effects. We present a case of ischemic colitis in a 42-year-old active duty service member after using the performance-enhancing supplement, NO-Xplode. In this report, we review the pharmacology of this supplement and its proposed mechanism of injury.
authors.affiliation: Department of Medicine, Walter Reed Army Medical Center, 6900 Georgia Avenue, Washington, DC 20307, USA.
authors.forename: Charles D
authors.initials: CD
authors.lastname: Magee
authors.forename: Fouad J
authors.initials: FJ
authors.lastname: Moawad
authors.forename: Frank
authors.initials: F
authors.lastname: Moses
mesh_terms: D000284:Administration, Oral; D000328:Adult; D017091:Colitis, Ischemic / Q000139:chemically induced* / Q000175:diagnosis; D003113:Colonoscopy; D003937:Diagnosis, Differential; D019587:Dietary Supplements / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008889:Military Personnel; D004366:Nonprescription Drugs / Q000008:administration & dosage / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D004366:Nonprescription Drugs