Polyethylene terephthalate may yield endocrine disruptors.
BACKGROUND
Recent reports suggest that endocrine disruptors may leach into the contents of bottles made from polyethylene terephthalate (PET). PET is the main ingredient in most clear plastic containers used for beverages and condiments worldwide and has previously been generally assumed not to be a source of endocrine disruptors.


OBJECTIVE
I begin by considering evidence that bottles made from PET may leach various phthalates that have been putatively identified as endocrine disruptors. I also consider evidence that leaching of antimony from PET containers may lead to endocrine-disrupting effects.


CONCLUSIONS
The contents of the PET bottle, and the temperature at which it is stored, both appear to influence the rate and magnitude of leaching. Endocrine disruptors other than phthalates, specifically antimony, may also contribute to the endocrine-disrupting effect of water from PET containers.


CONCLUSIONS
More research is needed in order to clarify the mechanisms whereby beverages and condiments in PET containers may be contaminated by endocrine-disrupting chemicals.
Sax
Leonard
L
Montgomery Center for Research in Child and Adolescent Development, Exton, Pennsylvania 19341, USA. MCRCAD@verizon.net
D000818:Animals; D000965:Antimony / Q000032:analysis / Q000737:chemistry / Q000633:toxicity; D001628:Beverages / Q000032:analysis; D001681:Biological Assay; D052244:Endocrine Disruptors / Q000032:analysis / Q000737:chemistry* / Q000633:toxicity; D018857:Food Packaging; D006801:Humans; D011093:Polyethylene Terephthalates / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity
D052244:Endocrine Disruptors; D011093:Polyethylene Terephthalates; D000965:Antimony