title: The recent US preventive services task force guidelines are not supported by the scientific evidence and should be rescinded.
abstract: The recent US Preventive Services Task Force (USPSTF) guidelines on mammographic screening ignore the scientific evidence and should be rescinded. There are no data to support the age of 50 years as a threshold for screening. There are no data to support screening women aged 40 to 49 years on the basis of risk. The USPSTF failed to understand the randomized controlled trials and used the lowest possible benefit in its calculations. The death rate from breast cancer has decreased by 30%, primarily because of screening. The agency ignored direct data with regard to decreasing deaths in real populations in favor of computer models. The USPSTF admits that its guidelines will result in unnecessary deaths from breast cancer that could be avoided by screening annually beginning at the age of 40 years.
authors.affiliation: Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, USA. dkopans@partners.org
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Kopans
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control; D005260:Female; D006287:Health Planning Guidelines; D006801:Humans; D008327:Mammography; D011315:Preventive Medicine / Q000592:standards* / Q000639:trends; D014481:United States