title: Complete remission of coronary vasculitis in Churg-Strauss Syndrome by prednisone and cyclophosphamide.
abstract: The heart is involved in up to 50% of all patients with Churg-Strauss syndrome, but vasculitis of the coronary arteries has only been rarely documented. We present a young patient with severe coronary aneurysms and stenotic lesions due to a Churg-Strauss vasculitis. Prompt therapy with prednisone and cyclophosphamide resulted in the complete resolution of all lesions.
authors.affiliation: Department of Internal Medicine, Division of Vascular Medicine, Radboud University Nijmegen Medical Center, Geert Grooteplein 21, PO Box 9101, 6500 HB Nijmegen, The Netherlands. N.Riksen@aig.umcn.nl
authors.forename: Niels P
authors.initials: NP
authors.lastname: Riksen
authors.forename: Helmut
authors.initials: H
authors.lastname: Gehlmann
authors.forename: Annemarie E
authors.initials: AE
authors.lastname: Brouwer
authors.forename: Marcel
authors.initials: M
authors.lastname: van Deuren
mesh_terms: D000293:Adolescent; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D003327:Coronary Disease / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D003331:Coronary Vessels / Q000187:drug effects / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D012074:Remission Induction; D016896:Treatment Outcome; D014657:Vasculitis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011239:Prednisolone