title: [A bowel perforation with metallic stent placement for advanced rectal cancer during bevacizumab-based chemotherapy].
abstract: A 61-year-old woman with an unresectable malignant rectal stricture underwent placement of an expandable metallic stent under endoscopic guidance. The stent was successfully implanted and her bowel obstruction was relieved. After treatment with bevacizumab for unresectable rectal cancer, she was admitted to our hospital because of rectal perforation. This case suggests that placement of a metallic stent in colorectal cancer cases may increase the risk of bowel perforation during bevacizumab-based chemotherapy.
authors.affiliation: Department of Gastroenterology, Toyonaka Municipal Hosipital, Japan. yosinami-te@mc.pref.osaka.jp
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Yoshinami
authors.forename: Makoto
authors.initials: M
authors.lastname: Ichiba
authors.forename: Shiro
authors.initials: S
authors.lastname: Hayashi
authors.forename: Katsumi
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Shibuya
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Higashimoto
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy*; D020533:Angiogenesis Inhibitors / Q000009:adverse effects*; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000628:therapy*; D015607:Stents / Q000009:adverse effects
chemical_list: D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab