Primary ovarian neuroblastoma.
BACKGROUND
The diagnosis of neuroblastoma is rare after the age of 15 years, and anatomical locations are essentially the adrenal glands and paraspinal sites. Neuroblastomas in adolescents are most often metastatic and carry a very poor prognosis.


METHODS
We report the case of a 17-year-old young woman in whom the diagnosis of primary ovarian neuroblastoma associated with a mature teratoma was established. A workup to assess disease extension was negative. Due to the localized characteristic of this tumor and the absence of N-myc oncogene amplification, and in spite of the unfavorable characteristic of the patient's age, treatment consisted of surgical removal of the tumor followed by clinical, laboratory and radiographic monitoring. No relapse has occurred during the 3-year follow up.


CONCLUSIONS
The issues raised by this rare case are discussed concomitantly with a review of the literature.
Muhlstein
Joël
J
Pôle de Gynécologie-Obstétrique et Reproduction, Maternité Régionale Universitaire, de Nancy, Nancy, France. joel.muhlstein@free.fr
Rodriguez-Dahlhoff
Sandra
S
Marie
Béatrice
B
Fouyssac
Fanny
F
D000293:Adolescent; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009447:Neuroblastoma / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D013724:Teratoma / Q000473:pathology* / Q000601:surgery