Fatal outcome of spontaneous cerebral and intraventricular hemorrhage in a child with idiopathic thrombocytopenic purpura (ITP)--case report.
BACKGROUND
Idiopathic thrombocytopenic purpura (ITP) is the most prevalent acquired hemorrhagic diathesis in children characterised by antibody-mediated destruction of platelets. ITP is generally a self-limiting benign disorder but despite this good prognosis, ITP carries the risk of severe bleeding (mainly intracranial) that may threaten the child's life.


METHODS
We describe a case of a 5-year-old girl with idiopathic thrombocytopenic purpura in the course of EBV infection with massive cerebral and intraventricular hemorrhage and fatal outcome.


CONCLUSIONS
This extremely rare case of intracranial haemorrhage in a child with ITP coexisting with EBV infection (a likely additional risk factor for hemorrhage) deserves attention considering the fatal outcome despite intensive treatment.
Brodkiewicz
Andrzej
A
Klinika Pediatrii, Hematologii i Onkologui Dzieciecej Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1,71-252 Szczecin
Peregud-Pogorzelski
Jarosław
J
Szychot
Elwira
E
Badowicz
Beata
B
Pakulski
Cezary
C
Marciniak
Hanna
H
D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*