title: [A case report of alverine-citrate-induced acute hepatitis].
abstract: Alverine citrate is one of the most commonly used antispasmodic drugs for patients with irritable bowel syndrome. Alverine-citrate-induced hepatotoxicity is extremely rare, with only a few cases having been reported worldwide. We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity.
authors.affiliation: Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. jin@inha.ac.kr.
authors.forename: Jee Young
authors.initials: JY
authors.lastname: Han
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Lee
authors.forename: Joon Mee
authors.initials: JM
authors.lastname: Kim
authors.forename: Kowoon
authors.initials: K
authors.lastname: Joo
authors.forename: Ung
authors.initials: U
authors.lastname: Chon
authors.forename: Jung Il
authors.initials: JI
authors.lastname: Lee
authors.forename: Seok
authors.initials: S
authors.lastname: Jeong
authors.forename: Don Haeng
authors.initials: DH
authors.lastname: Lee
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Kim
authors.forename: Kyung Sun
authors.initials: KS
authors.lastname: Min
mesh_terms: D000208:Acute Disease; D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D002951:Citrates / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000188:drug therapy; D008111:Liver Function Tests; D010276:Parasympatholytics / Q000009:adverse effects* / Q000627:therapeutic use; D011437:Propylamines / Q000009:adverse effects* / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D002951:Citrates; D010276:Parasympatholytics; D011437:Propylamines; C010846:alverine