title: An estimate of cancers attributable to occupational exposures in France.
abstract: OBJECTIVE
  To perform a quantitative estimate of the proportion of cancers attributable to occupational exposures in France in 2000.
  
  
  METHODS
  Exposure data for established carcinogens were obtained from a 1994 survey and other sources. Relative risks for 23 exposure-cancer combinations were derived from meta-analyses and pooled analyses.
  
  
  RESULTS
  A total of 4335 cases of cancer among men (2.7% of all cancers) and 403 cases among women (0.3% of all cancers) were attributed to occupational exposures. Asbestos, polycyclic aromatic hydrocarbons, and chromium VI were the main occupational carcinogens in men, and asbestos and involuntary smoking were the main carcinogens in women. Corresponding proportions for cancer deaths were 4.0% and 0.6% in men and women, respectively. Lung cancer represented 75% of deaths attributable to occupational exposures.
  
  
  CONCLUSIONS
  Our estimates are comparable with those obtained for other countries in studies based on similar methodology.
authors.affiliation: International Prevention Research Institute, Lyon, France.
authors.forename: Paolo
authors.initials: P
authors.lastname: Boffetta
authors.forename: Philippe
authors.initials: P
authors.lastname: Autier
authors.forename: Mathieu
authors.initials: M
authors.lastname: Boniol
authors.forename: Peter
authors.initials: P
authors.lastname: Boyle
authors.forename: Catherine
authors.initials: C
authors.lastname: Hill
authors.forename: André
authors.initials: A
authors.lastname: Aurengo
authors.forename: Roland
authors.initials: R
authors.lastname: Masse
authors.forename: Guy de
authors.initials: Gd
authors.lastname: Thé
authors.forename: Alain-Jacques
authors.initials: AJ
authors.lastname: Valleron
authors.forename: Roger
authors.initials: R
authors.lastname: Monier
authors.forename: Maurice
authors.initials: M
authors.lastname: Tubiana
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001194:Asbestos / Q000633:toxicity; D002273:Carcinogens / Q000633:toxicity*; D002857:Chromium / Q000633:toxicity; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology*; D009784:Occupational Diseases / Q000139:chemically induced* / Q000453:epidemiology*; D016273:Occupational Exposure; D011084:Polycyclic Aromatic Hydrocarbons / Q000633:toxicity; D012907:Smoking / Q000009:adverse effects; D055815:Young Adult
chemical_list: D002273:Carcinogens; D011084:Polycyclic Aromatic Hydrocarbons; D002857:Chromium; D001194:Asbestos