title: Muscle metastasis of low-grade endometrial carcinoma seven years after diagnosis: a case report.
abstract: BACKGROUND
  Early-stage low-grade endometrial carcinoma has an excellent prognosis. In few cases local relapse and/or distant metastases can occur. We report the muscle as an unusual site of metastasis.
  
  
  METHODS
  A 69-year-old woman underwent surgery for FIGO Stage IA, grade 1 endometrioid adenocarcinoma of the endometrium. After four years she had local relapse without response to chemoradiation, requiring pelvic exanteration. Three years later she was diagnosed with a deltoid muscle metastasis confirmed histologically and bone metastases. After failing hormone therapy, chemotherapy was administered. She died eight months after diagnosis of the bone and muscle metastases.
  
  
  CONCLUSIONS
  Low-risk endometrial carcinoma can behave like a high-risk group. Furthermore, this report describes, to our knowledge, the first case of endometrial carcinoma muscle metastasis.
authors.affiliation: Hospital Universitari Vall d'Hebron, Barcelona, Spain. amoaknin@vhebron.net
authors.forename: A
authors.initials: A
authors.lastname: Oaknin
authors.forename: M P
authors.initials: MP
authors.lastname: Barretina
authors.forename: I
authors.initials: I
authors.lastname: Morilla
mesh_terms: D000368:Aged; D001132:Arm; D018269:Carcinoma, Endometrioid / Q000175:diagnosis / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000556:secondary*; D018482:Muscle, Skeletal; D009364:Neoplasm Recurrence, Local