title: The true distal posterior inferior cerebellar artery aneurysm: clinical characteristics and strategy for treatment.
abstract: OBJECTIVE
  A series of aneurysms located at the 4 (th) or 5 (th) segment of the posterior inferior cerebellar artery (PICA) has not been previously reported in the literature. We report six such cases and analyze their clinical characteristics and outcomes from three different treatment strategies.
  
  
  METHODS
  We reviewed six patients with a diagnosis of distal PICA aneurysm. The following data were analyzed: age, sex, aneurysm size, Hunt-Hess grade at presentation, angiographic characteristics, and clinical treatment outcome determined by Glascow outcome scores (GOS). Treatments performed included clipping and wrapping, sacrificing the parent arteries of the aneurysms, and selective coiling.
  
  
  RESULTS
  Six patients (5 females, 1 male; mean age: 61.2 years; mean aneurysm size: 6.2 mm) presented at our facility with subarachnoid hemorrhage (SAH) caused by aneurysm rupture. Two patients presented with Hunt-Hess grades 4 and 5; all others were in Hunt-Hess grades 2 or 3. One patient died before surgery. Treatment outcomes of the surviving five patients were as follows: three patients had GOS of 5, one improved by operation, and another died from re-bleeding after selective coiling.
  
  
  CONCLUSIONS
  Surgery for the true distal PICA aneurysm results in good clinical outcomes. Clipping or wrapping should be considered as the first choice for treatment, and sacrificing the parent artery of the distal PICA aneurysm is relatively safer than selective coiling. The type of parent artery and particularly the collateralization of its distal part should be considered as an essential factor to take into consideration when choosing a treatment strategy.
authors.affiliation: Department of Neurosurgery, Xiehe Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, PR China. zhouyingchun8@hotmail.com
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: Y
authors.initials: Y
authors.lastname: Kato
authors.forename: O T
authors.initials: OT
authors.lastname: Olugbenga
authors.forename: S
authors.initials: S
authors.lastname: Hirotoshi
authors.forename: K
authors.initials: K
authors.lastname: Karagiozov
authors.forename: O
authors.initials: O
authors.lastname: Masahiro
authors.forename: S
authors.initials: S
authors.lastname: Amitendu
authors.forename: N
authors.initials: N
authors.lastname: Makoto
authors.forename: K
authors.initials: K
authors.lastname: Tetsuo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D001158:Arteries / Q000601:surgery; D002531:Cerebellum / Q000098:blood supply*; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D013525:Surgical Instruments; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed