title: Bioprosthetic mitral valve thrombosis less than one year after replacement and an ablative MAZE procedure: a case report.
abstract: Occurrence of bioprosthetic valve thrombosis less than a year after replacement is very uncommon. Here, we describe a case of a 57 year old male, who presented 10 months after receiving a bioprosthetic mitral valve replacement with a two week history of dyspnea on exertion, worsening orthopnea and decreased exercise tolerance. Echocardiography revealed severe mitral regurgitation (MR), thrombosis of the posterior mitral leaflet, left atrial (LA) mural thrombus and a depressed left ventricular ejection fraction of twenty-five percent. Given severe clot burden and decompensated heart failure (New York Heart Association - NYHA class III) repeat sternotomy was done to replace the bioprosthetic mitral valve and remove LA mural thrombus. MR was resolved postoperatively. This brief report further reviews promoting factors, established guidelines and management strategies of bioprosthetic valve thrombosis.
authors.affiliation: Department of Medicine, Emory University, Atlanta, Ga, USA. osaeed@emory.edu
authors.forename: Omar
authors.initials: O
authors.lastname: Saeed
authors.forename: Byron R
authors.initials: BR
authors.lastname: Williams
authors.forename: Melvin
authors.initials: M
authors.lastname: Ku
authors.forename: Omar M
authors.initials: OM
authors.lastname: Lattouf
mesh_terms: D001281:Atrial Fibrillation / Q000601:surgery; D001705:Bioprosthesis / Q000009:adverse effects*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D018450:Disease Progression; D004452:Echocardiography; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D056346:Sternotomy / Q000379:methods*