title: [Chronic gout: causes, clinical manifestations, treatment].
abstract: Why chronic gout, that is mostly a well diagnosed and controlled disease if it is timely and systematically treated with allopurinol, becomes a topical public health problem following 50 years after the introduction of pathogenetic therapy with xantine oxidase inhibitors is under consideration. The principles of rational therapy for chronic gouty arthritis are outlined.
authors.forename: V G
authors.initials: VG
authors.lastname: Barskova
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006073:Gout / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors
chemical_list: D006074:Gout Suppressants; D000493:Allopurinol; D014969:Xanthine Oxidase