Biological activities of 2-styrylchromones.
2-Styrylchromones (2-SC) are chromone derivatives characterized by the attachment of a styryl group to the 2-position of the chromone structure. The 2-styrylchromone structure has been demonstrated to bear important biological activities such as antiallergic, antitumor, affinity and selectivity for A(3) adenosine receptors, antiviral, antioxidant and anti-inflammatory. The aim of the present paper was to review the available information on this field.
Gomes
Ana
A
REQUIMTE, Departamento de Química-Física, Faculdade de Farmácia, Universidade do Porto, Rua Aníbal Cunha 164, Porto, Portugal.
Freitas
Marisa
M
Fernandes
Eduarda
E
Lima
José L F C
JL
D000818:Animals; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D002867:Chromones / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D043684:Receptor, Adenosine A3 / Q000378:metabolism; D012229:Rhinovirus / Q000187:drug effects; D013329:Structure-Activity Relationship; D013343:Styrenes / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*
D018926:Anti-Allergic Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D000975:Antioxidants; D000998:Antiviral Agents; D002867:Chromones; D043684:Receptor, Adenosine A3; D013343:Styrenes