MRICOM-MRI COntrast Modelling using 2D T1-T2 correlation spectra and relaxation signatures.
Image contrast is calculated by inputting experimental 2D T(1)-T(2) relaxation spectra into the ODIN software interface. The method involves characterising a magnetic resonance imaging pulse sequence with a "relaxation signature" which describes the sensitivity of the sequence to relaxation and is independent of sample parameters. Maximising (or minimising) the overlap between the experimental 2D T(1)-T(2) relaxation spectra and the relaxation signature can then be used to maximise image contrast. The concept is illustrated using relaxation signatures for the echo planar imaging and Turbo spin-echo imaging sequences, together with in-vitro 2D T(1)-T(2) spectra for liver and cartilage.
Wright
Kevin M
KM
Institute of Food Research, Norwich Research Park, Colney, Norwich, UK.
Warner
Joshua
J
Venturi
Luca
L
Piggott
Robert B
RB
Donell
Simon
S
Hills
Brian P
BP
D000465:Algorithms; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic