Epimerization of tea catechins under weakly acidic and alkaline conditions.
Tea catechins in a buffer at pH 7 with N(2) replacing O(2) epimerized rapidly at 80 degrees C with less than 10% of oxidative side reactions and gave catechin epimers in a 50-63% yield. The epimerization of catechins with three hydroxyl groups was faster than with two groups, and of galloyl-free catechins was faster than catechins with a galloyl ester.
Ishino
Nobuyoshi
N
The United Graduate School of Agricultural Science, Gifu University, Japan.
Yanase
Emiko
E
Nakatsuka
Shin-Ichi
S
D000143:Acids / Q000494:pharmacology; D002392:Catechin / Q000031:analogs & derivatives / Q000494:pharmacology*; D008968:Molecular Conformation
D000143:Acids; D002392:Catechin; C045651:epigallocatechin gallate