Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?
A recent paper in BMC Biology reports that actin stress fibers in adjacent cultured endothelial cells are linked through adherens junctions. This organization might provide a super-cellular network that could enable coordinated signaling and structural responses in endothelia.
Lampugnani
Maria Grazia
MG
IFOM, FIRC Institute of Molecular Oncology, via Adamello, 16-20139 Milan, Italy. mariagrazia.lampugnani@ifom-ieo-campus.it
D000199:Actins / Q000502:physiology*; D022005:Adherens Junctions / Q000502:physiology*; D002448:Cell Adhesion / Q000502:physiology; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000502:physiology*; D042783:Endothelial Cells / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology*; D006801:Humans; D015398:Signal Transduction / Q000502:physiology; D022502:Stress Fibers / Q000502:physiology*
D000199:Actins