title: Case report of Acremonium intraocular infection after cataract extraction.
abstract: A 64-year-old woman was referred to our clinic for the treatment of chronic uveitis in her left eye, which had started two weeks after an uncomplicated cataract extraction. She was treated with topical steroids with an initially good response, yet she subsequently developed severe inflammation and plaque-like material around the intraocular lens, despite continuous steroid therapy. She underwent pars plana vitrectomy, smear and culture of the aqueous and vitreous fluids, and intravitreal antibiotic injection under the impression of Propionibacterium acne (P. acne) endophthalmitis. As a result of the smear and culture of the vitreous fluid identified as an Acremonium species, she was treated with intravenous amphotericin B injections for five days, followed by oral voriconazole administration. During the post-operative 18-month follow-up, she was stable without significant relapse of uveitis. In this case, the best correction of visual acuity was an improvement from 20/40 to 20/20.
authors.affiliation: Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Soo Geun
authors.initials: SG
authors.lastname: Joe
authors.forename: Jongyoon
authors.initials: J
authors.lastname: Lim
authors.forename: Joo Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: Young Hee
authors.initials: YH
authors.lastname: Yoon
mesh_terms: D000164:Acremonium / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000627:therapeutic use; D002387:Cataract Extraction; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents