title: Antioxidant level in normal and dialyzed patients using FRAP method.
abstract: To examine the serum antioxidant levels like vit-C, vit-E and glutathione in patients with renal diseases who were subjected to dialysis and to evaluate the antioxidant by FRAP method. To find out the involvement of free radicals in pathogenesis of renal disease. Fifty patients with high levels of creatinine and urea level were included in the study of dialysis. A difference of antioxidant level of vit-C, vit-E and glutathione was observed. The study therefore suggests the importance of assessing these marker oxidative stress antioxidant capacities in renal disease during dialysis.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gomal University, D.I. Khan, Pakistan.
authors.forename: Ghulam
authors.initials: G
authors.lastname: Mustafa
authors.forename: Ikram Ullah
authors.initials: IU
authors.lastname: Khan
authors.forename: M Khalid
authors.initials: MK
authors.lastname: Khan
authors.forename: Mohammad
authors.initials: M
authors.lastname: Sualeh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000378:metabolism*; D001205:Ascorbic Acid / Q000097:blood; D001774:Blood Chemical Analysis / Q000379:methods*; D003404:Creatinine / Q000097:blood; D005978:Glutathione / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D008875:Middle Aged; D018384:Oxidative Stress; D006435:Renal Dialysis / Q000009:adverse effects*; D014508:Urea / Q000097:blood; D014810:Vitamin E / Q000097:blood
chemical_list: D000975:Antioxidants; D014810:Vitamin E; D014508:Urea; D003404:Creatinine; D005978:Glutathione; D001205:Ascorbic Acid