Vibrational spectroscopic study of salbutamol hemisulphate.
Salbutamol hemisulphate is a relatively selective beta(2)-adrenergic agonist and is used as a bronchodilator. In this work, we present a detailed vibrational spectroscopic investigation of salbutamol hemisulphate using mid-infrared and near-infrared Fourier-transform (NIR-FT) Raman spectroscopies. These data are supported by quantum chemical calculations, which allow us to characterise the vibrational spectra of this compound reasonably. As such, this study could be viable for examining the way in which this drug interacts with its target molecules.
Ali
H R H
HR
Chemical and Forensic Sciences/University Analytical Centre, School of Life Sciences, University of Bradford, Bradford BD7 1 DP, UK.
Edwards
H G M
HG
Kendrick
J
J
Scowen
I J
IJ
D000318:Adrenergic beta-Agonists / Q000737:chemistry*; D000420:Albuterol / Q000737:chemistry*; D001993:Bronchodilator Agents / Q000737:chemistry*; D011789:Quantum Theory; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D000420:Albuterol