title: Highly effective treatment with tacrolimus ointment in an adolescent with oral graft-versus-host disease.
abstract: METHODS
  We report a case of acute oral graft-versus-host disease in an adolescent, which was successfully treated with tacrolimus 0.1% ointment.
  
  
  CONCLUSIONS
  Although tacrolimus ointment is not licensed for the indication of oral GvHD, this case report provides preliminary evidence for a potential effectiveness of using tacrolimus in case of failure when GvHD is resistant.
authors.affiliation: Department of Pharmacy, Ghent University Hospital, -1 K12, De Pintelaan 185, 9000, Ghent, Belgium. tiene.bauters@uzgent.be
authors.forename: T
authors.initials: T
authors.lastname: Bauters
authors.forename: V
authors.initials: V
authors.lastname: Bordon
authors.forename: V
authors.initials: V
authors.lastname: Van de Velde
authors.forename: S
authors.initials: S
authors.lastname: Van Lancker
authors.forename: H
authors.initials: H
authors.lastname: Robays
authors.forename: Y
authors.initials: Y
authors.lastname: Benoit
authors.forename: G
authors.initials: G
authors.lastname: Laureys
mesh_terms: D000293:Adolescent; D006086:Graft vs Host Disease / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology*; D009824:Ointments; D016559:Tacrolimus / Q000008:administration & dosage*; D014059:Tongue / Q000473:pathology; D014060:Tongue Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D009824:Ointments; D016559:Tacrolimus