title: Computational genetic mapping in mice: the ship has sailed.
abstract: Computational haplotype-based genetic mapping can be used to discover new biological mechanisms, disease-related pathways, and unexpected uses for existing drugs. Here we discuss the benefits and limitations of this methodology, its impact on translational medicine, and its future course.
authors.affiliation: Department of Anesthesia, Stanford University, Stanford, CA, USA.
authors.forename: Ming
authors.initials: M
authors.lastname: Zheng
authors.forename: Steve
authors.initials: S
authors.lastname: Shafer
authors.forename: Guochun
authors.initials: G
authors.lastname: Liao
authors.forename: Hong-Hsing
authors.initials: HH
authors.lastname: Liu
authors.forename: Gary
authors.initials: G
authors.lastname: Peltz
mesh_terms: D000818:Animals; D051379:Mice / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci; D011995:Recombination, Genetic