title: Predictors of hepatitis knowledge improvement among methadone maintained clients enrolled in a hepatitis intervention program.
abstract: This randomized, controlled study (n = 256) was conducted to compare three interventions designed to promote hepatitis A virus (HAV) and hepatitis B virus (HBV) vaccination completion, among clients undergoing methadone maintenance treatment (MMT) in Los Angeles and Santa Monica. The participants were randomized into three groups: Motivational Interviewing-Single Session (MI-Single), Motivational Interviewing-Group (MI-Group), or Nurse-Led Hepatitis Health Promotion (HHP). All three treatment groups received the 3-series HAV/HBV vaccine. The MI sessions were provided by trained therapists, the Nurse-Led HHP sessions were delivered by a research nurse. The main outcome variable of interest was improvement in HBV and HCV knowledge, measured by a 6-item HBV and a 7-item HCV knowledge and attitude tool that was administered at baseline and at 6-month follow-up. The study results showed that there was a significant increase in HBV- and HCV-related knowledge across all three groups (p < 0.0001). There were no significant differences found with respect to knowledge acquisition among the groups. Irrespective of treatment group, gender (P = 0.008), study site (P < 0.0001) and whether a participant was abused as a child (P = 0.017) were all found to be predictors of HCV knowledge improvement; only recruitment site (P < 0.0001) was found to be a predictor of HBV knowledge. The authors concluded that, although MI-Single, MI-Group and Nurse-Led HHP are all effective in promoting HBV and HCV knowledge acquisition among MMT clients, Nurse-Led HHP may be the method of choice for this population as it may be easier to integrate and with additional investigation may prove to be more cost efficient.
authors.affiliation: UCLA, School of Nursing, 700 Tiverton Avenue, Los Angeles, CA 90095-1702, USA. anyamath@sonnet.ucla.edu
authors.forename: Adeline
authors.initials: A
authors.lastname: Nyamathi
authors.forename: Darlene
authors.initials: D
authors.lastname: Tyler
authors.forename: Karabi
authors.initials: K
authors.lastname: Sinha
authors.forename: Mary
authors.initials: M
authors.lastname: Marfisee
authors.forename: Allan
authors.initials: A
authors.lastname: Cohen
authors.forename: Barbara
authors.initials: B
authors.lastname: Greengold
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D007722:Health Knowledge, Attitudes, Practice; D006293:Health Promotion / Q000379:methods*; D006506:Hepatitis A / Q000517:prevention & control*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage; D006509:Hepatitis B / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage; D006801:Humans; D007406:Interview, Psychological / Q000379:methods; D008297:Male; D008691:Methadone / Q000008:administration & dosage; D008875:Middle Aged; D009042:Motivation; D024802:Nurse's Role; D015397:Program Evaluation
chemical_list: D022362:Hepatitis A Vaccines; D017325:Hepatitis B Vaccines; D008691:Methadone