title: Experimental evidence of strong anomalous diffusion in living cells.
abstract: We evaluated the transport of polymeric particles internalized into living cancer cells. The mean-square displacement demonstrates superdiffusion with a scaling exponent of 1.25. Scaling exponents of a range of displacement moments are bilinear with moment order, exhibiting slopes of 0.6 and 0.8. Thus, we present experimental evidence of strong anomalous diffusion. Bilinearity indicates that particle motion is composed of subdiffusive regimes separated by active yet nonballistic flights. We discuss the results in terms of particle interactions with their microenvironment.
authors.affiliation: Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa 32000, Israel.
authors.forename: Naama
authors.initials: N
authors.lastname: Gal
authors.forename: Daphne
authors.initials: D
authors.lastname: Weihs
mesh_terms: D000818:Animals; D001692:Biological Transport; D002470:Cell Survival; D004058:Diffusion; D006367:HeLa Cells; D006801:Humans; D009068:Movement; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D011108:Polymers / Q000378:metabolism*
chemical_list: D011108:Polymers