Amiodarone-induced alveolar haemorrhage: a rare complication of a common medication.
Amiodarone pulmonary toxicity (APT) is a common and distinctive form of drug-induced lung injury. Several patterns have been described and the most common pattern of APT is interstitial pneumonitis. However, amiodarone-induced diffused alveolar haemorrhage is rarely reported. We describe a case of early onset of APT manifested by respiratory distress, haemoptysis, severe hypoxia and bilateral pulmonary infiltrates that was finally diagnosed with amiodarone-induced diffuse alveolar haemorrhage. High suspicion of APT in patients with these non-specific clinical symptoms is needed. Early recognition and treatment are imperative.
Tanawuttiwat
Tanyanan
T
Department of Medicine, Advocate Christ Medical Center/University of Illinois at Chicago, 4440 West 95th Street, Oak Lawn, IL 60453, USA. ttanawuttiwat@gmail.com
Harindhanavudhi
Tasma
T
Hanif
Sara
S
Sahloul
Mohammad Z
MZ
D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D017809:Fatal Outcome; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000150:complications; D008297:Male; D008875:Middle Aged; D011650:Pulmonary Alveoli; D011654:Pulmonary Edema / Q000209:etiology
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone