title: Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions.
abstract: Iodine catalyzes the pseudo four-component reaction of an aldehyde, a urea or thiourea, and cyclic 1,3-dicarbonyl compounds under microwave irradiation in a solvent-free condition to yield various σ symmetric spiro heterobicyclic rings in excellent yields.
authors.affiliation: Medicinal Chemistry Division, North East Institute of Science and Technology, Jorhat, Assam, 785 006, India. dr_dprajapati2003@yahoo.co.uk
authors.forename: Dipak
authors.initials: D
authors.lastname: Prajapati
authors.forename: Debajyoti
authors.initials: D
authors.lastname: Bhuyan
authors.forename: Mukut
authors.initials: M
authors.lastname: Gohain
authors.forename: Wenhao
authors.initials: W
authors.lastname: Hu
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D055772:Green Chemistry Technology / Q000379:methods*; D007455:Iodine / Q000737:chemistry*; D008872:Microwaves; D012997:Solvents / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D012997:Solvents; D013141:Spiro Compounds; D007455:Iodine