title: Intrasac fibrin glue injection after platinum coils placement: the efficacy of a simple intraoperative procedure in preventing type II endoleak after endovascular aneurysm repair.
abstract: OBJECTIVE
  To verify in our experience if fibrin glue injection into the aneurysm sac, made at the end of endovascular aneurysm repair (EVAR), can reduce type II endoleak rates.
  
  
  METHODS
  Between January 2005 and February 2008, 38 patients underwent EVAR for an unruptured abdominal aortic aneurysm. The first 20 consecutive patients (Group A) had standard EVAR while the last 18 patients (Group B) had EVAR with fibrin glue injection into the sac, regardless of type II endoleak's presence.
  
  
  RESULTS
  There was no statistically significant difference between the two groups concerning the surgical time and the time of X-ray exposure (P=0.30 and 0.54, respectively). Type II endoleak rate was significantly higher in Group A compared to Group B (6 cases, 30% vs. 1 case, 5.5%, respectively, P=0.05). Primary short-term clinical success was 95% and 100%, respectively. At 12 months, selective lumbar embolization was performed in two patients in Group A and in one patient in Group B. Patients in Group A had less computed tomography (CT) studies than patients in Group B (2.0 vs. 1.2, respectively, P=0.024).
  
  
  CONCLUSIONS
  Fibrin glue injection is a safe procedure and seems to reduce type II endoleak rates. Patients who received this procedure had fewer CT examinations, with reduced health-care costs.
authors.affiliation: Operative Unit of Vascular and Endovascular Surgery, San Bortolo Hospital, Vicenza, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Pilon
authors.forename: Federico
authors.initials: F
authors.lastname: Tosato
authors.forename: Dario
authors.initials: D
authors.lastname: Danieli
authors.forename: Francesco
authors.initials: F
authors.lastname: Campanile
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Zaramella
authors.forename: Domenico
authors.initials: D
authors.lastname: Milite
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000191:economics / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis / Q000191:economics; D019917:Blood Vessel Prosthesis Implantation / Q000191:economics / Q000295:instrumentation*; D017046:Cost Savings; D004621:Embolization, Therapeutic / Q000191:economics; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage* / Q000191:economics; D017048:Health Care Costs; D006801:Humans; D015552:Injections, Intralesional; D007430:Intraoperative Care; D007558:Italy; D053208:Kaplan-Meier Estimate; D008297:Male; D011183:Postoperative Complications / Q000191:economics / Q000517:prevention & control*; D011475:Prosthesis Failure; D012189:Retrospective Studies; D013997:Time Factors; D014014:Tissue Adhesives / Q000008:administration & dosage* / Q000191:economics; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives