title: A new approach for hydroxyapatite coating on polymeric materials using laser-induced precursor formation and subsequent aging.
abstract: A new process, laser-induced precursor formation and subsequent aging in a supersaturated calcium phosphate aqueous solution (CP solution), was applied for coating a hydroxyapatite (HAP) film on a polymeric material, ethylene-vinyl alcohol copolymer (EVOH). Laser irradiation onto EVOH immersed in the CP solution induced the formation of CP precursors, and an HAP film composed of a submicrometer-scale cavernous structure was formed by subsequent aging in a CP solution without laser irradiation. The resulting HAP film coated on EVOH demonstrated excellent structural and chemical uniformity and cell adhesion with the CHO-K1 and BHK-21 cells. This process provides a practical technique for coating HAP onto polymeric materials.
authors.affiliation: Nanoarchitectonics Research Center (NARC), National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan. 200hee@hanyang.ac.kr
authors.forename: Baek-Hee
authors.initials: BH
authors.lastname: Lee
authors.forename: Ayako
authors.initials: A
authors.lastname: Oyane
authors.forename: Hideo
authors.initials: H
authors.lastname: Tsurushima
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sasaki
authors.forename: Naoto
authors.initials: N
authors.lastname: Koshizaki
mesh_terms: D000818:Animals; D016466:CHO Cells; D002448:Cell Adhesion; D002460:Cell Line; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D006224:Cricetinae; D003412:Cricetulus; D017886:Durapatite / Q000737:chemistry*; D007834:Lasers; D046529:Microscopy, Electron, Transmission / Q000379:methods; D011108:Polymers / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors
chemical_list: D020099:Coated Materials, Biocompatible; D011108:Polymers; D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer; D017886:Durapatite