title: Microbiology and visual outcome of bleb-associated endophthalmitis.
abstract: OBJECTIVE
  To identify the microbiological spectrum and visual outcome of bleb-associated endophthalmitis.
  
  
  METHODS
  The medical records of patients treated for bleb-associated endophthalmitis were reviewed.
  
  
  RESULTS
  Seventy-five patients were identified. Vitreous cultures were positive in 48 (64%) patients. The most common isolates were Streptococcus species in 24 (50%) eyes, gram-negative bacteria in 10 (20.8%) eyes, and Staphylococcus epidermidis in 7 (14.6%) eyes. Good visual outcome was achieved in 33 (44%) patients. On univariate analysis, shorter interval from onset of symptoms and treatment (p = .005), better initial visual acuity (p = .004), clear cornea at presentation (p = .048), isolation of less virulent organisms (p < .001), and absence of diabetes mellitus (p = .048) were significant positive predictors for good visual outcome.
  
  
  CONCLUSIONS
  Bleb-associated endophthalmitis is associated with severe visual impairment. Clinical features associated with better visual outcome include early presentation, better presenting visual acuity, clear cornea at presentation, culture of a less virulent organism, and absence of diabetes mellitus.
authors.affiliation: Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Turki A
authors.initials: TA
authors.lastname: Al-Turki
authors.forename: Sami
authors.initials: S
authors.lastname: Al-Shahwan
authors.forename: Hani S
authors.initials: HS
authors.lastname: Al-Mezaine
authors.forename: Dustan
authors.initials: D
authors.lastname: Kangave
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Abu El-Asrar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000145:classification* / Q000302:isolation & purification; D001768:Blister / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012529:Saudi Arabia; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents