Heroin-assisted treatment in the Netherlands: History, findings, and international context.
This monograph describes the history, findings and international context of heroin-assisted treatment (HAT) in the Netherlands. The monograph consists of (1) a short introduction and seven paragraphs describing the following aspects of HAT in the Netherlands: (2) history of HAT studies and implementation of routine HAT in the Netherlands; (3) main findings on efficacy, safety and cost-effectiveness from the two randomized controlled HAT trials in the Netherlands; (4) new findings from a large cohort study on the effectiveness of HAT in routine clinical practice in the Netherlands; (5) unique data on the patient's perspective of HAT; (6) data on the pharmacological and pharmaceutical basis for HAT in the Netherlands; (7) description of the registration process; and (8) account of the international context of HAT. Together, these data show that HAT can now be considered a safe and proven-effective intervention for the treatment of chronic, treatment-resistant heroin dependent patients.
Blanken
Peter
P
Central Committee on the Treatment of Heroin Addicts (CCBH), Utrecht, The Netherlands.
van den Brink
Wim
W
Hendriks
Vincent M
VM
Huijsman
Ineke A
IA
Klous
Marjolein G
MG
Rook
Elisabeth J
EJ
Wakelin
Jennifer S
JS
Barendrecht
Cas
C
Beijnen
Jos H
JH
van Ree
Jan M
JM
D000328:Adult; D003362:Cost-Benefit Analysis; D011307:Drug Prescriptions; D005260:Female; D003932:Heroin / Q000008:administration & dosage*; D006556:Heroin Dependence / Q000188:drug therapy* / Q000453:epidemiology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D009294:Narcotics / Q000008:administration & dosage*; D009426:Netherlands / Q000453:epidemiology; D011788:Quality of Life / Q000523:psychology; D016032:Randomized Controlled Trials as Topic / Q000191:economics / Q000266:history / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome
D009294:Narcotics; D003932:Heroin