title: [Rickets vitamin-D-dependent type 2].
abstract: Rickets is a rare child disease especially in developed countries. Nutritional rickets remains the most prevalent condition, although congenital forms are well known. In the latest group, vitamin D dependent rickets type II is the rarest form and it can course with or without alopecia. There is a mutation on the receptor for vitamin D, with peripheral resistance to the vitamin D action. The authors present two clinical cases of vitamin D dependent rickets type II, in which the alopecia was a peculiar clinical sign that allowed the diagnoses. With prolonged calcium infusions, we achieved normal seric levels of calcium and correct bone disorders; alopecia persisted. This treatment is the most effective way to control the disease.
authors.affiliation: Unidade de Nefrologia Pediátrica, Hospital Pediátrico de Coimbra, Coimbra.
authors.forename: Raquel
authors.initials: R
authors.lastname: Santos
authors.forename: Sérgio
authors.initials: S
authors.lastname: Neves
authors.forename: Clara
authors.initials: C
authors.lastname: Gomes
authors.forename: Farela
authors.initials: F
authors.lastname: Neves
authors.forename: António Jorge
authors.initials: AJ
authors.lastname: Correia
mesh_terms: D000293:Adolescent; D053098:Familial Hypophosphatemic Rickets / Q000145:classification* / Q000175:diagnosis; D006801:Humans; D008297:Male