[The role of peptides in aging control: results and prospects of research].
The paper summarizes results of long-term research designed to elucidate mechanisms of aging and evaluate efficacy of peptide bioregulators for the prevention of age-specific pathology. Peptides obtained by up-to-date methods in Russia, U.S.A., U.K., Germany, Italy, Spain, and France are reviewed. A molecular model is proposed to describe complementary interactions of short-chain peptides with gene promoters underlying initiation of protein synthesis. Prospects for the use of peptide bioregulators to prevent premature aging of the employable population in Russia are discussed.
Khavinson
V Kh
VKh
Anisimov
V N
VN
D000375:Aging / Q000378:metabolism*; D000818:Animals; D035843:Biomedical Research; D006801:Humans; D010455:Peptides / Q000502:physiology*
D010455:Peptides