Region-based diagnostic performance of multidetector CT for detecting peritoneal seeding in ovarian cancer patients.
OBJECTIVE
To determine the accuracy of multi-detector CT (MDCT) compared with the surgical findings, such as peritoneal seeding and metastatic lymph nodes, in ovarian cancer patients.


METHODS
Fifty-seven FIGO stage IA-IV ovarian cancer patients, who underwent MDCT before primary surgery, were included in this study. Two radiologists evaluated the following imaging findings in consensus: the presence of nodular, plaque-like or infiltrative soft-tissue lesions in peritoneal fat or on the serosal surface; presence of ascites; parietal peritoneal thickening or enhancement; and small bowel wall thickening or distortion. We also evaluated the presence of lymph node metastases. To allow region-specific comparisons, the peritoneal cavity was divided into 13 regions and retroperitoneal lymph nodes were divided into 3 regions. Descriptive statistical data were thus obtained.


RESULTS
The MDCT sensitivity, specificity, positive predictive values, and negative predictive values were 45, 72, 46, and 72%, respectively, for detecting peritoneal seeding and 21, 90, 52, and 69%, respectively, for detecting lymph node metastasis.


CONCLUSIONS
MDCT is moderately accurate for detecting peritoneal metastasis and lymph node metastasis in ovarian cancer patients.
Choi
Hyuck Jae
HJ
Department of Radiology, Asan Medical Center, University of Ulsan, Ulsan, Korea.
Lim
Myong Cheol
MC
Bae
Jaeman
J
Cho
Kyoung-Sik
KS
Jung
Dae Chul
DC
Kang
Sokbom
S
Yoo
Chong Woo
CW
Seo
Sang-Soo
SS
Park
Sang-Yoon
SY
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D009366:Neoplasm Seeding; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D010529:Peritoneal Cavity / Q000000981:diagnostic imaging; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed