title: Immediate loading of dental implants placed in periodontally infected and non-infected sites: a 4-year follow-up clinical study.
abstract: BACKGROUND
  The aim of the present study is to compare the outcomes of immediate loading of implants in replacing teeth with and without chronic periodontal lesions at 4 years of follow-up.
  
  
  METHODS
  Thirty-seven patients were included in this study. A total of 275 implants were placed and immediately loaded in extraction sockets, 197 in periodontally infected sites (infected sites group [IG]), and 78 implants in non-infected sites (non-infected sites group [NG]). Marginal bone levels and clinical parameters (plaque accumulation and bleeding index) were evaluated at baseline and 12, 24, and 48 months after implant placement. Comparisons between IG and NG values over time were performed by the Student two-tailed t test.
  
  
  RESULTS
  At 48 months of follow-up, the IG presented a survival rate of 98.9% because two implants were lost 1 month after placement; the NG reported a survival rate of 100%. The marginal bone level was 0.79 +/- 0.38 mm for the IG and 0.78 +/- 0.38 mm for the NG, plaque accumulation was 0.72 +/- 0.41 for the IG and 0.71 +/- 0.38 for the NG, and the bleeding index was 0.78 +/- 0.23 for the IG and 0.75 +/- 0.39 for the NG. No statistically significant differences were reported between the IG and NG over time and between time points.
  
  
  CONCLUSIONS
  At 48 months of follow-up, dental implants that were placed and immediately loaded in periodontally infected sockets showed no significant differences compared to implants placed in uninfected sites.
authors.affiliation: Department of Dentistry, Vita Salute University, San Raffaele Hospital, Milan, Italy. robcresp@libero.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Crespi
authors.forename: Paolo
authors.initials: P
authors.lastname: Capparè
authors.forename: Enrico
authors.initials: E
authors.lastname: Gherlone
mesh_terms: D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000209:etiology; D000539:Alveolar Process / Q000000981:diagnostic imaging; D003442:Crowns; D000044:Dental Abutments; D015921:Dental Implants; D019250:Dental Implants, Single-Tooth; D003766:Dental Occlusion; D003774:Dental Plaque Index; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D003824:Denture, Complete; D003829:Denture, Partial; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D010149:Postoperative Pain / Q000209:etiology; D010510:Periodontal Diseases / Q000601:surgery*; D010512:Periodontal Index; D010518:Periodontitis / Q000209:etiology; D011446:Prospective Studies; D011859:Radiography; D020390:Tooth Socket / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants