Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.
Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC(50) value of 190 microM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC(50) values of 80 microM-, 140 microM-, and 120 microM-.
Shabana
Samah
S
Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan.
Kawai
Azusa
A
Kai
Kenji
K
Akiyama
Kohki
K
Hayashi
Hideo
H
D005419:Flavonoids / Q000494:pharmacology*; D000432:Methanol; D019697:Onions / Q000737:chemistry; D031647:Psidium / Q000737:chemistry; D011794:Quercetin / Q000494:pharmacology*; D012431:Rutin; D014510:Urease
D005419:Flavonoids; C519462:guaijaverin; C041388:avicularin; D012431:Rutin; D011794:Quercetin; D014510:Urease; D000432:Methanol