Enantioselective construction of allylic phosphine oxides through substitution of Morita-Baylis-Hillman carbonates with phosphine oxides.
The asymmetric organocatalytic allylic substitution reaction of MBH carbonates with phosphine oxides has been developed. This organocatalytic approach constitutes an easy and efficient method for the direct preparation of allylic phosphine oxides in high enantioselectivities.
Hong
Liang
L
State Key Laboratory of Applied Organic Chemistry and Institute of Biochemistry and Molecular Biology, Lanzhou University, Lanzhou, 730000, China.
Sun
Wangsheng
W
Liu
Chunxia
C
Zhao
Depeng
D
Wang
Rui
R
D000498:Allyl Compounds / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009930:Organic Chemicals / Q000737:chemistry; D010087:Oxides / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D013237:Stereoisomerism
D000498:Allyl Compounds; D002254:Carbonates; D009930:Organic Chemicals; D010087:Oxides; D010720:Phosphines; C044646:phosphine