Passive cigarette smoke exposure and soft contact lens wear.
OBJECTIVE
To prospectively investigate the effects of passive cigarette smoke exposure on the ocular surface and tear film in soft contact lens (SCL) wearers.


METHODS
Twelve right eyes of 12 SCL wearers without any ocular or systemic diseases and 10 right eyes of 10 subjects who never wore CLs were examined before and 2 h after 5 min of passive cigarette smoke exposure in a controlled smoke chamber. Tear evaporation rate measurement, tear film break-up time (TBUT) examination, ocular surface fluorescein, rose bengal stainings, and Schirmer I test were performed at each visit.


RESULTS
The mean tear evaporation rates, TBUTs, and vital staining scores were significantly worse in CL wearers compared with healthy control subjects. TBUTs showed significant worsening after passive smoke exposure in both groups. The mean tear evaporation rate and vital staining scores showed a significant increase with brief passive smoke exposure in subjects not wearing CLs but not in CL wearers.


CONCLUSIONS
Even brief passive exposure to cigarette smoke is associated with adverse effects on the ocular surface as evidenced by an increase in tear instability and damage to the ocular surface epithelia in SCL wearers and non-CL wearers.
Ward
Samantha K
SK
Johnson and Johnson, Department of Ocular Surface and Visual Optics, Keio University School of Medicine, Tokyo, Japan.
Dogru
Murat
M
Wakamatsu
Tais
T
Ibrahim
Osama
O
Matsumoto
Yukihiro
Y
Kojima
Takashi
T
Sato
Enrique Adan
EA
Ogawa
Junko
J
Schnider
Cristina
C
Negishi
Kazuno
K
Tsubota
Kazuo
K
D000328:Adult; D003263:Contact Lenses, Hydrophilic; D003315:Cornea / Q000187:drug effects* / Q000378:metabolism; D015352:Dry Eye Syndromes / Q000139:chemically induced / Q000378:metabolism / Q000534:rehabilitation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012016:Reference Values; D012307:Risk Factors; D013666:Tears / Q000187:drug effects / Q000378:metabolism*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D014028:Tobacco Smoke Pollution