[A bowel perforation with metallic stent placement for advanced rectal cancer during bevacizumab-based chemotherapy].
A 61-year-old woman with an unresectable malignant rectal stricture underwent placement of an expandable metallic stent under endoscopic guidance. The stent was successfully implanted and her bowel obstruction was relieved. After treatment with bevacizumab for unresectable rectal cancer, she was admitted to our hospital because of rectal perforation. This case suggests that placement of a metallic stent in colorectal cancer cases may increase the risk of bowel perforation during bevacizumab-based chemotherapy.
Yoshinami
Tetsuhiro
T
Department of Gastroenterology, Toyonaka Municipal Hosipital, Japan. yosinami-te@mc.pref.osaka.jp
Ichiba
Makoto
M
Hayashi
Shiro
S
Yamamoto
Katsumi
K
Shibuya
Mitsuhiko
M
Higashimoto
Yoshifumi
Y
D000230:Adenocarcinoma / Q000628:therapy*; D020533:Angiogenesis Inhibitors / Q000009:adverse effects*; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000628:therapy*; D015607:Stents / Q000009:adverse effects
D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab