title: Compartment pressure of the rectus sheath accurately reflects intra-abdominal pressure in a porcine model.
abstract: BACKGROUND
  To investigate whether the compartment pressure of the rectus sheath (CPRS) reflects the intra-abdominal pressure (IAP) under various conditions of intra-abdominal hypertension (IAH) in a pig model.
  
  
  METHODS
  
  
  
  METHODS
  Prospective experimental study with in vivo pressure measurements.
  
  
  METHODS
  Institute for Clinical and Experimental Surgery, University of Saarland.
  
  
  METHODS
  Seven domestic male pigs (body weight 34.8+/-2.5 kg).
  
  
  METHODS
  Stepwise increase and decrease of IAP by means of CO(2) pneumoperitoneum. Continuous direct measurement of the IAP and correspondent indirect IAP measurement techniques including analysis of intravesical pressure (IVP), femoral vein pressure (FVP), and CPRS.
  
  
  RESULTS
  Bland-Altman analysis comparing direct IAP measurement with correspondent CPRS showed good agreement for IAP between 12 mm Hg and 30 mm Hg (bias -0.5 mm Hg, lower and upper limits of agreement (LLA/ULA) -3.5/2.5 mm Hg). FVP (bias -0.3 mm Hg, LLA/ULA -2.3/1.6 mm Hg) and IVP (bias 0.4 mm Hg, LLA/ULA -2.1/2.9 mm Hg) demonstrated similar results compared with direct IAP measurement. Agreement was worse for all indirect IAP measurement techniques for IAP<12 mm Hg.
  
  
  CONCLUSIONS
  CPRS accurately reflects IAP for IAP> or =12 mm Hg. Accuracy is similar to established indirect IAP measurement techniques.
authors.affiliation: Division of Trauma Surgery, Department of Surgery, University Hospital Zurich, Switzerland.
authors.forename: Emanuel
authors.initials: E
authors.lastname: Benninger
authors.forename: Matthias W
authors.initials: MW
authors.lastname: Laschke
authors.forename: Markus
authors.initials: M
authors.lastname: Cardell
authors.forename: Joerg H
authors.initials: JH
authors.lastname: Holstein
authors.forename: Burkhardt
authors.initials: B
authors.lastname: Seifert
authors.forename: Marius
authors.initials: M
authors.lastname: Keel
authors.forename: Otmar
authors.initials: O
authors.lastname: Trentz
authors.forename: Michael D
authors.initials: MD
authors.lastname: Menger
authors.forename: Christoph
authors.initials: C
authors.lastname: Meier
mesh_terms: D000005:Abdomen / Q000503:physiopathology*; D000818:Animals; D002404:Catheterization / Q000009:adverse effects; D003161:Compartment Syndromes / Q000503:physiopathology*; D004487:Edema / Q000209:etiology / Q000517:prevention & control; D005268:Femoral Vein / Q000503:physiopathology; D008297:Male; D023421:Models, Animal; D011027:Pneumoperitoneum / Q000503:physiopathology*; D011312:Pressure; D017568:Rectus Abdominis / Q000503:physiopathology*; D015427:Reperfusion Injury / Q000209:etiology / Q000517:prevention & control; D013552:Swine