title: [Polyradiomodification as component of combined treatment of rectal cancer: rationale and results].
abstract: The report discusses our 30-year experience with surgical and combined treatment of rectal cancer. In cases of preoperative radiotherapy, loco-regional frequency of relapse dropped to 9.6% as compared with surgery (16.3%). After preoperative thermoradiotherapy it fell to 4.6%; polyradiomodification - 0.5% (3-year follow-up). Distant metastasis formation rates were: after polyradiomodification--1.5%, radiotherapy--9.6%, and thermo-radiotherapy--6%. Recurrence-free survival rates (3 years) were: polyradiomodification--97.3%, thermo-radiotherapy--75.9%, radiotherapy--71.1%, and surgery--58%. Data on regimens and dosage of polyradiomodification alongside radiation damage for different combinations of treatment are presented.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Barsukov
authors.forename: S I
authors.initials: SI
authors.lastname: Tkachev
authors.forename: N D
authors.initials: ND
authors.lastname: Oltarzhevskaia
authors.forename: A G
authors.initials: AG
authors.lastname: Perevoshchikov
authors.forename: M A
authors.initials: MA
authors.lastname: Korovina
authors.forename: A V
authors.initials: AV
authors.lastname: Nikolaev
authors.forename: V V
authors.initials: VV
authors.lastname: Glebovskaia
authors.forename: D V
authors.initials: DV
authors.lastname: Kuz'michev
authors.forename: V A
authors.initials: VA
authors.lastname: Aliev
authors.forename: Z Z
authors.initials: ZZ
authors.lastname: Mamedli
authors.forename: A M
authors.initials: AM
authors.lastname: Pavlova
mesh_terms: D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D018714:Radiotherapy, Adjuvant / Q000379:methods; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome