[Evaluation of the endothelial monolayer after re-endothelization of the thoracic duct cryodestruction area].
Using the standard cryodestruction model, the peculiarities of reparative regeneration were studied in cat thoracic duct endothelium. Material was collected 12 hours, 1, 2 and 3 days after the injury and was analyzed using scanning electron microscopy. The restoration of the endothelial layer was shown to be completed by day 3 due to cell migration and proliferation at the margin of cryodestruction zone. The degree of tissue regeneration was evaluated using the topological and informational parameters. The results demonstrated the imperfect completion of regeneration process by day 3; the borderline state of the cellular system was detected together with the possibility of the disturbance of endothelial lining reorganization process. Thus, the informational parameters may be used as the complementary criteria for the assessment of the processes, cellular system state and functioning.
Sesorova
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Lazorenko
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D000818:Animals; D002415:Cats; D003080:Cold Temperature / Q000009:adverse effects; D004729:Endothelium, Lymphatic / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D007257:Information Theory; D008297:Male; D008854:Microscopy, Electron; D012038:Regeneration; D013897:Thoracic Duct / Q000473:pathology* / Q000648:ultrastructure