title: Syntheses of amorphous and crystalline cupric sulfide nanoparticles and study on the specific activities on different cells.
abstract: Copper sulfide amorphous nanoparticles and nanocrystals were prepared successfully by a special process. These CuS nanoparticles could specifically and significantly induce the apoptosis and inhibit the proliferation of human cancer cells rather than normal cells. Moreover, the biological activities of these nanoparticles are related to their polymorphs.
authors.affiliation: College of Chemistry and Environmental Science, Henan Normal University, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Xinxiang 453007, PR China.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Guo
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Yang
authors.forename: Huajie
authors.initials: H
authors.lastname: Wang
authors.forename: Feifei
authors.initials: F
authors.lastname: Wang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D003300:Copper / Q000737:chemistry / Q000494:pharmacology*; D003460:Crystallization; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D013440:Sulfides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013499:Surface Properties; D014961:X-Ray Diffraction
chemical_list: D000970:Antineoplastic Agents; D013440:Sulfides; C099343:cuprous sulfide; D003300:Copper