Sclerosing angiomatoid nodular transformation of the spleen: multimodality imaging findings and pathologic correlate.
Sclerosing angiomatoid nodular transformation of the spleen is a recently recognized benign vascular lesion, characterized microscopically by multiple angiomatoid nodules embedded within a fibrosclerotic stroma. Although its imaging manifestations have been limited in the radiologic literature, features such as low-level increased fluorodeoxyglucose activity on a positron emission tomographic scan, near-complete blending in with normal splenic parenchyma on a delayed-phase image, and the presence of radiating scarring on a magnetic resonance image may suggest the diagnosis. We report here the computed tomographic, magnetic resonance imaging, and positron emission tomographic findings of sclerosing angiomatoid nodular transformation, along with gross and microscopic pathological correlation.
Subhawong
Ty K
TK
The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital, Baltimore, MD 21287, USA. tsubhaw1@jhmi.edu
Subhawong
Andrea P
AP
Kamel
Ihab
I
D000328:Adult; D000798:Angiomatosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D019275:Radiopharmaceuticals; D012598:Sclerosis / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013156:Splenectomy; D013158:Splenic Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D019275:Radiopharmaceuticals