title: Treatment of idiopathic hemifacial spasm with radiosurgery or hypofractionated stereotactic radiotherapy: preliminary results.
abstract: BACKGROUND
  Microvascular decompression in the posterior cranial fossa is the first treatment option for hemifacial spasm. For patients not suitable for surgery because of advanced age, poor general conditions or patients who refuse surgery, radiotherapeutic treatment could be an alternative. Only one case of resolution of hemifacial spasm in a patient undergoing radiosurgery for an intracanalicular vestibular schwannoma has been described in the literature. In this article we present three patients affected by idiopathic hemifacial spasm, refractory to medical therapy and botulinum toxin injections, who were treated by radiosurgery in one case and hypofractionated stereotactic radiotherapy in the other two.
  
  
  METHODS
  Radiosurgery, with a single dose of 8 Gy, was used in the first patient affected by idiopathic hemifacial spasm and autoimmune polyneuropathy with severe hypoacusia; hypofractionated stereotactic radiotherapy, with 15 Gy in 5 fractions of 3 Gy each, was preferred in the other 2 cases. In all patients, the target consisted of the vestibulocochlear-facial bundle immediately before its entry into the internal acoustic foramen.
  
  
  RESULTS
  A marked improvement of symptoms was observed in 2 patients, and almost complete disappearance in the other case, with no complications, particularly, auditory.
  
  
  CONCLUSIONS
  The mean follow-up time of 24 months reported here could be judged too short, and our series too small, but the good results observed so far lead us to underline that, as in trigeminal neuralgia, radiosurgery or hypofractionated stereotactic radiotherapy could represent a therapeutic alternative to microvascular decompression for idiopathic hemifacial spasm for patients not suitable for surgery.
authors.affiliation: Department of Neurosciences, University of Rome Tor Vergata, Rome, Italy. b.fraioli@libero.it
authors.forename: M F
authors.initials: MF
authors.lastname: Fraioli
authors.forename: L
authors.initials: L
authors.lastname: Moschettoni
authors.forename: C
authors.initials: C
authors.lastname: Fraioli
authors.forename: L
authors.initials: L
authors.lastname: Strigari
mesh_terms: D000328:Adult; D000368:Aged; D003056:Cochlear Nerve / Q000473:pathology / Q000601:surgery*; D019299:Decompression, Surgical / Q000379:methods; D005154:Facial Nerve / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D019569:Hemifacial Spasm / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D016634:Radiosurgery / Q000379:methods*; D014725:Vestibular Nerve / Q000473:pathology / Q000601:surgery*