title: SIFT and shape information incorporated into fluid model for non-rigid registration of ultrasound images.
abstract: Non-rigid registration of ultrasound images takes an important role in image-guided radiotherapy and surgery. Intensity-based method is popular in non-rigid registration, but it is sensitive to intensity variations and has problems with matching small structure features for the existence of speckles in ultrasound images. In this paper, we develop a new algorithm integrating the intensity and feature of ultrasound images. Both global shape information and local keypoint information extracted by scale invariant feature transform (SIFT) are incorporated into intensity similarity measure as the body force of viscous fluid model in a Bayesian framework. Experiments were performed on synthetic and clinical ultrasound images of breast and kidney. It is shown that shape and keypoint information significantly improves fluid model for non-rigid registration, especially for alignment of small structure features in accuracy.
authors.affiliation: College of Biomedical Engineering, South-Central University for Nationalities, Wuhan 430074, PR China. luxsyyl@gmail.com
authors.forename: Xuesong
authors.initials: X
authors.lastname: Lu
authors.forename: Su
authors.initials: S
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
authors.forename: Yazhu
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D001499:Bayes Theorem; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D008962:Models, Theoretical; D014463:Ultrasonography; D016217:Ultrasonography, Mammary