Intramolecular imino Diels-Alder approach to the synthesis of the aspidosperma alkaloid from 3,5-dibromo-2-pyrone.
A new synthetic route to the key framework of aspidosperma alkaloid was devised from the cycloadduct of 3-(2-nitrophenyl)-5-bromo-2-pyrone via intramolecular imino Diels-Alder reaction.
Nguyen
Thanh Tam
TT
Department of Chemistry, Hanyang University, Seoul 133-791, Korea.
Jung
Eun-Ju
EJ
Cho
Cheon-Gyu
CG
D000470:Alkaloids / Q000138:chemical synthesis*; D010084:Oxidation-Reduction; D011753:Pyrones / Q000737:chemistry*
C450850:3,5-dibromo-2-pyrone; D000470:Alkaloids; D011753:Pyrones