[Clinical analysis of laryngeal neuroendocrine carcinoma].
OBJECTIVE
To investigate the clinical characteristics and therapy of laryngeal neuroendocrine carcinoma (LNEC).


METHODS
Ten cases of LNEC treated in our department were retrospectively analyzed.


RESULTS
Eight out of 10 cases were were atypical carcinoid: 1 case treated as supraglottic horizontal partial laryngectomy died 22 months after operation; 1 case was lost; the other 6 cases were followed up for more than 2 years. Two cases were small cell type, one received supra-cricoid partial laryngectomy-cricohyoidopexy (SCPL-CHP), neck dissection, and radiotherapy, but died after 14 months; the other was receiving radiotherapy.


CONCLUSIONS
LNEC is a rare malignant tumor and the diagnosis relies on clinical characteristics, histopathological and immunohistochemistry examination. The different types of LNEC should give different treatment protocols.
Li
Cai
C
Department of Otolaryngology-Head and Neck Surgery, the Eye Ear Nose Throat Hospital, Fudan University, Shanghai, 200031, China. drlicai@hotmail.com
Zhou
Liang
L
Shen
Yan
Y
Zhu
Li
L
D000328:Adult; D000368:Aged; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies