[Evaluation of the mutagenicity of detergents by tests on bacteria, plant cells and human leucocytes.].
The aim of this study was to evaluate the mutagenicity of several traditional detergents and that of newer more biodegradable detergents, by using a bacterial test (Ames test), a plant cell test (Allium cepa micronuclei test) and a human leucocyte test (Comet test). All tests were conducted using a wide range of doses (1-2000 mg/l). None of the examined detergents induced mutations in S.typhimurium. One traditional detergent showed a genotoxic effect with the A. cepa test, while all newer detergents and one traditional detergent were shown by the Comet test to be capable of inducing DNA damage.
Feretti
Donatella
D
Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Igiene, Epidemiologia e Sanità Pubblica, Università degli Studi di Brescia.
Pedrazzani
Roberta
R
Ceretti
Elisabetta
E
Zerbini
Ilaria
I
Gozio
Eleonora
E
Belotti
Caterina
C
Alias
Carlotta
C
Donato
Francesco
F
Gelatti
Umberto
U
D001419:Bacteria; D003902:Detergents; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens; D059828:Plant Cells; D012486:Salmonella typhimurium / Q000187:drug effects
D003902:Detergents; D009153:Mutagens