title: Clinical and radiological long-term results after operative treatment of chondroblastoma.
abstract: BACKGROUND
  The aim of this study was the investigation of radiological and clinical long-term results after surgery for chondroblastoma in a single orthopedic oncological center.
  
  
  METHODS
  As much as 24 patients were enrolled in the study using an in-house tumor data-base (age, sex, patient history, clinical symptoms, type of surgery, complications, and histological results), radiological findings (localization/size of the lesion, Lodwick-classification, Enneking-stages, and local recurrence), and clinical investigation (Enneking score). Mean follow-up was 8 years.
  
  
  RESULTS
  Preferred sites were the knee-joint (distal femur 6, proximal tibia 6), followed by the proximal humerus (8), and the proximal femur. As much as 3 lesions were judged inactive, 13 active, and 8 aggressive. Apart from one case, all lesions were treated by curettage and filling of the defect by bone cement and/or cancellous bone chips. Only one patient suffered local recurrence after primary resection of the tumor (4.2%). About 87.5% of our patients reached a very good or good functional result (Enneking score 28-30).
  
  
  CONCLUSIONS
  Our results further support curettage and defect filling even of active/aggressive chondroblastoma. If performed betimes, the surgical therapeutic concept of accurate intralesional curettage with or without local adjuvant therapy and defect packing with cancellous bone grafts and/or bone cement assures a high chance of joint preservation along with a low rate of recurrence and good functional long-term results.
authors.affiliation: Division of Orthopedic Oncology and Septic Surgery, Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany.
authors.forename: Burkhard
authors.initials: B
authors.lastname: Lehner
authors.forename: Daniela
authors.initials: D
authors.lastname: Witte
authors.forename: Stefan
authors.initials: S
authors.lastname: Weiss
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D002648:Child; D002804:Chondroblastoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D003475:Curettage; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012189:Retrospective Studies; D013977:Tibia; D016896:Treatment Outcome; D055815:Young Adult