title: Biograft-HT as a bone graft material in the treatment of periodontal vertical defects and its clinical and radiological evaluation: Clinical study.
abstract: OBJECTIVE
  To determine the efficacy of Biograft-HT((R)) as a bone graft material in the treatment of vertical defects in generalized chronic periodontitis patients and their clinical and radiological evaluation.
  
  
  METHODS
  Twenty patients diagnosed with generalized chronic periodontitis having two or more vertical defects were selected for this study. Clinical parameters like plaque index, gingival index, probing pocket depth and clinical attachment levels were recorded at different points of time over six months. Radiographic evaluation included the depth of the bone defect and the percentage of bone defect fill and was carried out for both the groups at baseline, three months and six months. After recording clinical parameters and administering phase-1 therapy, the sites were randomly treated either with Biograft- HT((R)) or open flap debridement only.
  
  
  RESULTS
  At the end of six months there was a significant reduction in the plaque and gingival scores in both test and control groups. There was 64% decrease in probing pocket depth for the test site as compared to 54.52% decrease seen for the control group. Similarly there was an 84.82% gain in clinical attachment level from the baseline to six months post operatively for the experimental group in comparison to 68.83% gain for the control group. Furthermore, 43.57% bone fill was observed for the experimental site whereas only 17.98% of bone fill was evident in the control site.
  
  
  CONCLUSIONS
  Biograft -HT improves healing outcomes, leads to a reduction of probing depth, a resolution of osseous defects and a gain in clinical attachment, compared with open flap debridement by itself.
authors.affiliation: Department of Periodontics, Darshan Dental College, Udaipur, Rajasthan, India.
authors.forename: K T
authors.initials: KT
authors.lastname: Chandrashekar
authors.forename: Chhavi
authors.initials: C
authors.lastname: Saxena