title: Laboratory evaluation of novaluron as a rodent feed-through insecticide against sand fly larvae (Diptera: Psychodidae).
abstract: Experiments were conducted to evaluate novaluron as a feed-through larvicide to control immature phlebotomine sand flies (Phlebotomus papatasi Scopoli) (Diptera: Psychodidae). The minimum effective concentration of novaluron against sand fly larvae fed hamster feces treated with novaluron, or feces of hamsters fed a diet containing novaluron, was 9.88 and 9.88 x 10(-1) mg/kg, respectively. Feces of novaluron-treated hamsters were held under conditions simulating the inside of a rodent burrow for up to 30 d, and all larvae that consumed these feces died before pupation; a significant reduction in treated larval survival relative to control was observed when the feces were aged for up to 150 d. Novaluron was shown to be effective as a feed-though larvicide when novaluron-treated food made up only a portion of the diet of hamsters. The results of this study suggest that novaluron could be effective as a rodent feed-through insecticide in a field setting.
authors.affiliation: Department of Entomology, Louisiana State University Agricultural Center, Agricultural Experiment Station, 402 Life Sciences, Baton Rouge, LA 70803, USA. tmascari@agcenter.lsu.edu
authors.forename: T M
authors.initials: TM
authors.lastname: Mascari
authors.forename: L D
authors.initials: LD
authors.lastname: Foil
mesh_terms: D000818:Animals; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000737:chemistry / Q000469:parasitology; D007300:Insect Control / Q000379:methods*; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D010671:Phenylurea Compounds / Q000737:chemistry / Q000494:pharmacology*; D010691:Phlebotomus / Q000187:drug effects*; D012377:Rodentia
chemical_list: D007306:Insecticides; D010671:Phenylurea Compounds; C471805:novaluron