title: Region-based diagnostic performance of multidetector CT for detecting peritoneal seeding in ovarian cancer patients.
abstract: OBJECTIVE
  To determine the accuracy of multi-detector CT (MDCT) compared with the surgical findings, such as peritoneal seeding and metastatic lymph nodes, in ovarian cancer patients.
  
  
  METHODS
  Fifty-seven FIGO stage IA-IV ovarian cancer patients, who underwent MDCT before primary surgery, were included in this study. Two radiologists evaluated the following imaging findings in consensus: the presence of nodular, plaque-like or infiltrative soft-tissue lesions in peritoneal fat or on the serosal surface; presence of ascites; parietal peritoneal thickening or enhancement; and small bowel wall thickening or distortion. We also evaluated the presence of lymph node metastases. To allow region-specific comparisons, the peritoneal cavity was divided into 13 regions and retroperitoneal lymph nodes were divided into 3 regions. Descriptive statistical data were thus obtained.
  
  
  RESULTS
  The MDCT sensitivity, specificity, positive predictive values, and negative predictive values were 45, 72, 46, and 72%, respectively, for detecting peritoneal seeding and 21, 90, 52, and 69%, respectively, for detecting lymph node metastasis.
  
  
  CONCLUSIONS
  MDCT is moderately accurate for detecting peritoneal metastasis and lymph node metastasis in ovarian cancer patients.
authors.affiliation: Department of Radiology, Asan Medical Center, University of Ulsan, Ulsan, Korea.
authors.forename: Hyuck Jae
authors.initials: HJ
authors.lastname: Choi
authors.forename: Myong Cheol
authors.initials: MC
authors.lastname: Lim
authors.forename: Jaeman
authors.initials: J
authors.lastname: Bae
authors.forename: Kyoung-Sik
authors.initials: KS
authors.lastname: Cho
authors.forename: Dae Chul
authors.initials: DC
authors.lastname: Jung
authors.forename: Sokbom
authors.initials: S
authors.lastname: Kang
authors.forename: Chong Woo
authors.initials: CW
authors.lastname: Yoo
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Seo
authors.forename: Sang-Yoon
authors.initials: SY
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D009366:Neoplasm Seeding; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D010529:Peritoneal Cavity / Q000000981:diagnostic imaging; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed