title: Single-nucleotide evolutionary constraint scores highlight disease-causing mutations.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Cooper
authors.forename: David L
authors.initials: DL
authors.lastname: Goode
authors.forename: Sarah B
authors.initials: SB
authors.lastname: Ng
authors.forename: Arend
authors.initials: A
authors.lastname: Sidow
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bamshad
authors.forename: Jay
authors.initials: J
authors.lastname: Shendure
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Nickerson
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D015894:Genome, Human; D006801:Humans; D008957:Models, Genetic; D009154:Mutation