title: The fundamentals of tooth movement.
abstract: Advances in the field of molecular phenomena have led to a fuller understanding of the mechanisms at work in tooth movement. The forces applied by orthodontic devices are converted into cellular signals via the deformation of the bony walls and the inflammatory reaction they trigger. In turn, the numerous cytokines, which are created by this process activate other messengers which differentiate, activate and inhibit the different cell populations involved in tooth movement.
authors.affiliation: Faculté d'odontologie de Marseille, hôpital de La Timone, Marseille, France. msjlegall@aol.com
authors.forename: Michel
authors.initials: M
authors.lastname: Le Gall
authors.forename: Julien
authors.initials: J
authors.lastname: Sastre
mesh_terms: D000539:Alveolar Process / Q000502:physiology; D001696:Biomechanical Phenomena; D016723:Bone Remodeling / Q000502:physiology*; D019245:Compressive Strength; D003799:Dental Stress Analysis; D006801:Humans; D010006:Osteoblasts / Q000502:physiology; D010010:Osteoclasts / Q000502:physiology; D015398:Signal Transduction; D013718:Tensile Strength; D014087:Tooth Movement Techniques