Iron-catalyzed N-alkylation of azoles via oxidation of C-H bond adjacent to an oxygen atom.
Azole derivatives were synthesized by iron-catalyzed oxidative reactions of azoles and ethers in good to excellent yields. A wide variety of azoles and ethers were selectively transformed into the corresponding oxidative coupling products under neutral reaction conditions.
Pan
Shiguang
S
Department of Chemistry, Renmin University of China, Beijing 100872, China.
Liu
Jinhua
J
Li
Huanrong
H
Wang
Zhenyu
Z
Guo
Xingwei
X
Li
Zhiping
Z
D000478:Alkylation; D001393:Azoles / Q000737:chemistry*; D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*
D001393:Azoles; D007501:Iron; D010100:Oxygen