[Partial ejaculatory duct obstruction induces hemospermia syndrome in the rat model].
OBJECTIVE
To investigate the pathogenesis of hematospermia syndrome using the rat model of hemospermia induced by partial ejaculatory duct obstruction.


METHODS
Fifty male rats were divided into Groups A (n=20) and B (n=30), the former subjected to incomplete ligation of the right ejaculatory duct, while the latter open-close sham operation. Electro-stimulation was performed for ejaculation induction one week after the operation. Those that developed hematospermia in Group A were chosen as Group A1, while those with normal ejaculation in Group B included in Group B1. The semen indexes and seminal vesicle pressure were compared between Groups A1 and B1.


RESULTS
Compared with Group B1, Group A1 showed significantly decreased semen volume (P < 0.01), lower sperm motility (P < 0.01) and higher seminal vesicle pressure (P < 0.01), but no statistically significant differences were observed in the WBC count and sperm density in the semen between the two groups (P > 0.05).


CONCLUSIONS
Hemospermia syndrome can be induced by partial ejaculatory duct obstruction, with changes of semen indexes, and it is closely correlated with high seminal vesicle pressure.
Xiao
Fei
F
Institute of Men's Health Management, Peking University People's Hospital, Beijing 100044, China.
Bai
Wen-jun
WJ
Wang
Xiao-feng
XF
D000818:Animals; D004195:Disease Models, Animal; D004543:Ejaculatory Ducts / Q000473:pathology*; D051516:Hemospermia / Q000209:etiology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley