Thermostable enzymes as biocatalysts in the biofuel industry.
Lignocellulose is the most abundant carbohydrate source in nature and represents an ideal renewable energy source. Thermostable enzymes that hydrolyze lignocellulose to its component sugars have significant advantages for improving the conversion rate of biomass over their mesophilic counterparts. We review here the recent literature on the development and use of thermostable enzymes for the depolymerization of lignocellulosic feedstocks for biofuel production. Furthermore, we discuss the protein structure, mechanisms of thermostability, and specific strategies that can be used to improve the thermal stability of lignocellulosic biocatalysts.
Yeoman
Carl J
CJ
Institute for Genomic Biology, University of Illinois, Urbana, Illinois, USA.
Han
Yejun
Y
Dodd
Dylan
D
Schroeder
Charles M
CM
Mackie
Roderick I
RI
Cann
Isaac K O
IK
D055162:Biocatalysis; D056804:Biofuels; D018533:Biomass; D004795:Enzyme Stability; D004950:Esterases / Q000737:chemistry / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000737:chemistry / Q000378:metabolism*; D006358:Hot Temperature; D008031:Lignin / Q000378:metabolism; D011487:Protein Conformation
D056804:Biofuels; C036909:lignocellulose; D008031:Lignin; D004950:Esterases; D006026:Glycoside Hydrolases