[Impaired gustatory sensitivity of the tongue to table salt as a risk factor of arterial hypertension].
The study included 630 patients with verified diagnosis of arterial hypertension (AH) in whom 24 hr AP monitoring was performed, threshold gustatory sensitivity of the tongue to table salt (TGS) measured, and habit to add salt to the cooked food evaluated. Measurement of Na in daily urine of 442 patients was followed by estimation of salt consumption. The results were compared with those obtained in 100 patients with newly diagnosed AH. The control group comprised 288 subjects. TGS in AH patients was significantly higher than in controls and directly related to clinical features of the disease, high AP values, age, smoking habits, hypercholesterolemia, abdominal-type obesity, and hereditary predisposition. TGS positively correlated with daily urinary excretion of NaCl (r = 0.4-0.7; p < 0.05-0.01). High TGS decreased under effect of hypotensive therapy.
Volkov
V S
VS
Poseliugina
O B
OB
Nilova
S A
SA
Vinogradova
T S
TS
Rokkina
S A
SA
Svistunov
O P
OP
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D001795:Blood Pressure Determination; D018450:Disease Progression; D004408:Dysgeusia / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology / Q000652:urine; D008297:Male; D008875:Middle Aged; D012965:Sodium Chloride / Q000652:urine; D017673:Sodium Chloride, Dietary / Q000493:pharmacokinetics*; D055697:Taste Perception / Q000502:physiology*; D013652:Taste Threshold / Q000502:physiology*
D017673:Sodium Chloride, Dietary; D012965:Sodium Chloride