Neutrophil function after bone marrow and hematopoietic stem cell transplant.
Bone marrow and hematopoietic stem cell transplants are life saving procedures for a variety of hematologic malignancies. Unfortunately, long-term survival is significantly impacted by the development of invasive fungal and bacterial infections, in part attributable to innate and adaptive immunologic defects post-transplant. This review focuses specifically on neutrophil function after autologous and allogeneic bone marrow and hematopoietic stem cell transplant.
Ramaprasad
Charulata
C
Section of Infectious Diseases, University of Chicago Hospital, Chicago, IL 60637, USA. charulata.ramaprasad@gmail.com
Pouch
Stephanie
S
Pitrak
David L
DL
D000818:Animals; D016026:Bone Marrow Transplantation; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D009504:Neutrophils / Q000502:physiology*