title: [Preparation of submicron emulsion of fresh Zhongjiefeng volatile oil].
abstract: OBJECTIVE
  To prepare the submicron emulsion of fresh Zhongjiefeng volatile oil.
  
  
  METHODS
  The Zhongjiefeng volatile oil submicron emulsion was obtained after passing the elementary emulsion through a high pressure homogenizer. The physical and chemical stability of the emulsion was evaluated with the stability parameter of centrifugation, appearance of emulsion and the pH. The formulation and processing factors were optimized by single factor reviewing and orthogonal experimental design.
  
  
  RESULTS
  By controlling various processing factors and optimizing formulation, the stable submicron emulsion of Zhongjiefeng volatile oil was prepared. Its mean particle diameter was 164-169 nm with PDI 0.084-0.107 and Zeta electric potential was -40 mV.
  
  
  CONCLUSIONS
  The formulation and preparation technique of the emulsion is reasonable.
authors.affiliation: Zhejiang Chinese Medical University, Hangzhou 310053, China.
authors.forename: Suxiang
authors.initials: S
authors.lastname: Wu
authors.forename: Guiyuan
authors.initials: G
authors.lastname: Lv
authors.forename: Suhong
authors.initials: S
authors.lastname: Chen
authors.forename: Shengna
authors.initials: S
authors.lastname: Zhang
authors.forename: Lishan
authors.initials: L
authors.lastname: Zhao
authors.forename: Rihe
authors.initials: R
authors.lastname: Zhou
authors.forename: Huakang
authors.initials: H
authors.lastname: Zhou
mesh_terms: D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D004655:Emulsions; D009822:Oils, Volatile