title: [Progress in the research of therapeutic enzyme].
abstract: With the development of the research on biotechnology and modern pharmacy, the application of enzyme drugs have grown rapidly and enzyme drugs have become an important branch of biopharmaceutics. In this article, some new varieties of therapeutic enzymes, enzyme targets, mechanisms and new technologies of application in therapeutic enzymes were reviewed, and the direction of development of therapeutic enzymes were discussed.
authors.affiliation: Department of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Hanmei
authors.initials: H
authors.lastname: Xu
authors.forename: Changlin
authors.initials: C
authors.lastname: Zhou
authors.forename: Heng
authors.initials: H
authors.lastname: Zhen
authors.forename: Wutong
authors.initials: W
authors.lastname: Wu
mesh_terms: D000243:Adenosine Deaminase / Q000235:genetics* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D056947:Enzyme Replacement Therapy / Q000379:methods*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D011486:Protein C / Q000235:genetics / Q000627:therapeutic use; D016337:RNA, Catalytic / Q000235:genetics* / Q000627:therapeutic use; D013300:Streptokinase / Q000235:genetics / Q000627:therapeutic use; D014568:Urokinase-Type Plasminogen Activator / Q000235:genetics / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D005343:Fibrinolytic Agents; D011486:Protein C; D016337:RNA, Catalytic; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator; D000243:Adenosine Deaminase