title: Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.
abstract: Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC(50) value of 190 microM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC(50) values of 80 microM-, 140 microM-, and 120 microM-.
authors.affiliation: Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Japan.
authors.forename: Samah
authors.initials: S
authors.lastname: Shabana
authors.forename: Azusa
authors.initials: A
authors.lastname: Kawai
authors.forename: Kenji
authors.initials: K
authors.lastname: Kai
authors.forename: Kohki
authors.initials: K
authors.lastname: Akiyama
authors.forename: Hideo
authors.initials: H
authors.lastname: Hayashi
mesh_terms: D005419:Flavonoids / Q000494:pharmacology*; D000432:Methanol; D019697:Onions / Q000737:chemistry; D031647:Psidium / Q000737:chemistry; D011794:Quercetin / Q000494:pharmacology*; D012431:Rutin; D014510:Urease
chemical_list: D005419:Flavonoids; C519462:guaijaverin; C041388:avicularin; D012431:Rutin; D011794:Quercetin; D014510:Urease; D000432:Methanol