Hepatobiliary neuroendocrine carcinoma: a case report.
BACKGROUND
Neuroendocrine carcinoma of the gallbladder is a rather uncommon disease. We report a case of a neuroendocrine tumor that was located in the wall of the gallbladder and that extended into the liver.


METHODS
A 52-year-old Caucasian woman presented with right-sided abdominal pain, ascites and jaundice. An MRI scan revealed a tumor mass located in the gallbladder wall and involving the liver. A partial hepatectomy and cholecystectomy were performed. Histology revealed a neuroendocrine tumor, which showed scattered Grimelius positive cells and immuno-expressed epithelial and endocrine markers. Our patient is undergoing chemotherapy treatment.


CONCLUSIONS
Gastroenteropancreatic neuroendocrine tumors need a multidisciplinary approach, involving immunohistochemistry and molecular-genetic techniques.
Manxhuka-Kerliu
Suzana
S
Petrusevska
Gordana
G
Maloku
Halit
H
Sahatciu-Meka
Vjollca
V
Loxha
Sadushe
S
Loxha
Naim
N
Shahini
Labinot
L