[Elucidation of mechanism underlying amyloid-beta peptide aggregation and its neurotoxicity expression and inhibition of these molecular processes by beneficial synthetic and natural compounds with low-molecular weights-new approaches to fundamental treatment and prevention of Alzheimer's disease].
Yamakuni
Tohru
T
Tohoku University, Sendai, Japan. yamakuni@mail.pharm.tohoku.ac.jp
D000371:Agglutination; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000517:prevention & control; D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors / Q000502:physiology; D016229:Amyloid beta-Peptides / Q000378:metabolism* / Q000633:toxicity*; D000818:Animals; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D009637:Masoprocol / Q000494:pharmacology / Q000627:therapeutic use; D008970:Molecular Weight
D016229:Amyloid beta-Peptides; D004791:Enzyme Inhibitors; D009637:Masoprocol; D053829:Amyloid Precursor Protein Secretases