title: New xanthate-based radical cyclization onto alkynes.
abstract: To bypass the failure of radical cyclization involving a xanthate transfer on alkynes, a new reductive cyclization strategy has been completed with the use of a stoichiometric amount of dilauroyl peroxide in isopropanol. When the starting xanthates are prepared via a Ugi 4-component reaction with propargylamine, exomethylene lactams are formed in good yields.
authors.affiliation: Laboratoire Chimie et Procédés, UMR 7652, Ecole Nationale Supérieure des Techniques Avancées, 32 Bd Victor, 75015 Paris, France. laurent.elkaim@ensta.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: El Kaïm
authors.forename: Laurence
authors.initials: L
authors.lastname: Grimaud
authors.forename: Luis D
authors.initials: LD
authors.lastname: Miranda
authors.forename: Emilie
authors.initials: E
authors.lastname: Vieu
authors.forename: M-Angeles
authors.initials: MA
authors.lastname: Cano-Herrera
authors.forename: Karel
authors.initials: K
authors.lastname: Perez-Labrada