5-(Dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide as a novel bifunctional antitumor agent and two-photon induced bio-imaging probe.
A novel compound, (5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide), was prepared and characterized; it shows dual functional roles as an effective antitumor and a two-photon induced bio-imaging agent.
Chui
C-H
CH
Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, PR China.
Wang
Q
Q
Chow
W-C
WC
Yuen
M C-W
MC
Wong
K-L
KL
Kwok
W-M
WM
Cheng
G Y-M
GY
Wong
R S-M
RS
Tong
S-W
SW
Chan
K-W
KW
Lau
F-Y
FY
Lai
P B-S
PB
Lam
K-H
KH
Fabbri
E
E
Tao
X-M
XM
Gambari
R
R
Wong
W-Y
WY
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D017785:Photons; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
C552069:5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide; D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D009281:Naphthalenes; D013449:Sulfonamides