title: An easy and fast ultrasonic selective S-alkylation of hetaryl thiols at room temperature.
abstract: A series of 2-alkylthio derivatives of hetaryl thiols were synthesized by selective S-alkylation with alkyl halides (bromides and iodides) with ultrasonic irradiation at room temperature. The reaction was found to be generally applicable to hetaryl thiol derivatives with different substituents in the aromatic nucleus and various alkyl halides. The reaction gives high to excellent yields of products with high purity.
authors.affiliation: University of Sofia, Faculty of Chemistry, 1164 Sofia, Bulgaria.
authors.forename: Todor
authors.initials: T
authors.lastname: Deligeorgiev
authors.forename: Stefka
authors.initials: S
authors.lastname: Kaloyanova
authors.forename: Nedyalko
authors.initials: N
authors.lastname: Lesev
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Vaquero
mesh_terms: D000478:Alkylation; D006219:Halogens / Q000737:chemistry* / Q000528:radiation effects*; D013010:Sonication; D013438:Sulfhydryl Compounds / Q000737:chemistry* / Q000528:radiation effects*; D013696:Temperature
chemical_list: D006219:Halogens; D013438:Sulfhydryl Compounds