title: Infratemporal fossa metastasis from carcinoma of the uterine cervix.
abstract: BACKGROUND
  Carcinoma of the uterine cervix is the fourth commonest malignant tumor in women. The disease spreads into the surrounding tissues by direct infiltration whereas spread by hematogenous dissemination is relatively unusual, and most commonly involves the lung, bone, and liver. The involvement of oral and maxillofacial region is extremely rare in gynecological cancer.
  
  
  METHODS
  In this paper, we present an unusual case of a metastatic squamous cell carcinoma originating in the infratemporal fossa of a 37-year-old woman who had underwent a subtotal hysterectomy, for squamous cell carcinoma of the cervix, 22 months earlier. A whole-body CT scan revealed a mass of enlarged lymph nodes in the mediastinum as well. The patient, who had presented for evaluation of a rapidly increasing trismus associated with deep intermittent facial pain and temporal swelling had initially been treated for a TMJ dysfunction and later for an infratemporal fossa abscess for long before a definite diagnosis was made. A high index of suspicion is possible to make an early diagnosis, which when coupled with an aggressive management can improve survival and quality of life.
authors.affiliation: University Clinic of Oral and Maxillofacial Surgery, G. Papanikolaou General Hospital, P. Mela 28, 546 22 Thessaloniki, Greece. idim@dent.auth.gr
authors.forename: Ioannis
authors.initials: I
authors.lastname: Dimitrakopoulos
authors.forename: Aris
authors.initials: A
authors.lastname: Ntomouchtsis
authors.forename: Fotis
authors.initials: F
authors.lastname: Iordanidis
mesh_terms: D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008207:Lymphatic Metastasis; D009360:Neoplastic Cells, Circulating; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000473:pathology; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D013701:Temporal Bone / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014313:Trismus / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D051598:Whole Body Imaging