title: [Research on liposoluble ingredients of Quchiling].
abstract: OBJECTIVE
  To study the liposoluble ingredients of Quchiling (LQ), which enter the blood and the brain,and to confirm the active ingredients of LQ in vivo.
  
  
  METHODS
  Serum pharmacochemistry and gas chromatography mass spectroscopy were used to analyze ingredients of LQ entering the blood and the brain.
  
  
  RESULTS
  There were eleven ingredients of LQ to enter the blood and six ingredients of LQ to enter the brain.
  
  
  CONCLUSIONS
  It is confirmed that eleven ingredients of LQ entered the blood, which are beta-asarone, schisandrol A, schisandrol B, deoxyschisandrin, schisandrin B, schisantherrin A, schisantherrin B, schisantherrin C, delta-cadinene, delta-cadinol and calamendiol in the blood, and that six ingredients are beta-asarone, schisandrol A, schisandrol B, deoxyschisandrin, schisandrin B and calamendiol in the brain.
authors.affiliation: Neuropharmacological Research Laboratory, College of Pharmacy, Jinan University, Guangzhou 510632, China. qyk968150@office.jnu.edu.cn
authors.forename: Wen
authors.initials: W
authors.lastname: Weng
authors.forename: Fei
authors.initials: F
authors.lastname: Xiao
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Li
authors.forename: Qin
authors.initials: Q
authors.lastname: Gao
authors.forename: Huanmin
authors.initials: H
authors.lastname: Luo
mesh_terms: D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000737:chemistry / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D034242:Cyclooctanes / Q000737:chemistry / Q000378:metabolism; D004149:Dioxoles / Q000737:chemistry / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000378:metabolism* / Q000493:pharmacokinetics*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D017705:Lignans / Q000737:chemistry / Q000378:metabolism; D008297:Male; D011083:Polycyclic Compounds / Q000737:chemistry / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000081248:Allylbenzene Derivatives; D000840:Anisoles; D034242:Cyclooctanes; D004149:Dioxoles; D004365:Drugs, Chinese Herbal; D017705:Lignans; D011083:Polycyclic Compounds; C012195:asarone; C520474:schisandrol A; C015499:schizandrin B; C033585:schizandrol B; C034734:schizandrin A