title: [Involvement of hemoglobin in the therapeutic action of blood ultraviolet irradiation].
abstract: The objective of this work was to study the mechanism of therapeutic action of extracorporeal ultraviolet irradiation of circulating blood and to evaluate the possibility of its application to combined treatment of patients with acute coronary syndrome. It was shown that ultraviolet irradiation causes photodissociation ofoxyhemoglobin thereby altering the oxygen-carrying function of the blood and improving oxygen supply to cells and tissues. The UV-induced modification of blood properties not only prevents tissue hypoxia but also triggers a cascade of metabolic processes. Taken together, these effects have beneficial influence on the clinical course of cardiovascular and other diseases.
authors.forename: V S
authors.initials: VS
authors.lastname: Ulashchik
authors.forename: G A
authors.initials: GA
authors.lastname: Zalesskaia
authors.forename: I I
authors.initials: II
authors.lastname: Kalosha
authors.forename: N P
authors.initials: NP
authors.lastname: Mit'kovskaia
mesh_terms: D000208:Acute Disease; D003327:Coronary Disease / Q000097:blood* / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008297:Male; D010108:Oxyhemoglobins / Q000378:metabolism*; D013577:Syndrome; D014466:Ultraviolet Rays; D014467:Ultraviolet Therapy / Q000379:methods*
chemical_list: D010108:Oxyhemoglobins