Case of bilateral retinal neovascularization associated with chronic idiopathic myelofibrosis.
We report a case of bilateral peripheral retinal neovascularization and chronic idiopathic myelofibrosis in a 69-year-old man. Ophthalmic examination revealed peripheral retinal nonperfusion with retinal neovascularization in both eyes and vitreous hemorrhage in the right eye. Fluorescein angiography of both eyes showed a marked midperipheral and peripheral avascular retina temporally with arteriovenous anastomosis and sea-fan neovascularizations. Blood tests showed pancytopenia and teardrop-shaped red blood cells, and bone marrow examination showed hypocellular marrow with severe fibrosis. The neovascularization was regressed following pars plana vitrectomy in the right eye and scatter laser photocoagulation in the left. The results suggest that peripheral retinal vessel occlusion and neovascularization may be associated with idiopathic myelofibrosis.
Kim
Moon Jung
MJ
Department of Ophthalmology, Seoul National University College of Medicine and Sensory Organ Research Institute, Seoul National University Medical Research Center, Seoul, Korea.
Yu
Hyeong Gon
HG
D000368:Aged; D002908:Chronic Disease; D005451:Fluorescein Angiography; D006801:Humans; D008028:Light Coagulation; D008297:Male; D055728:Primary Myelofibrosis / Q000150:complications*; D015861:Retinal Neovascularization / Q000150:complications* / Q000628:therapy; D014792:Visual Acuity; D014821:Vitrectomy; D014823:Vitreous Hemorrhage / Q000150:complications* / Q000628:therapy