title: The role of vaccination in the control of sars.
abstract: We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels of self-isolation among untraced infected individuals are explored. Bounds on the proportion of pre-outbreak successfully vaccinated individuals are provided using the the basic reproductive number. Uncertainty and sensitivity analyses on the reproductive number are carried out. The final epidemic size under different vaccination scenarios is computed.
authors.affiliation: Department of Mathematics, Harvey Mudd College, 340 E. Foothill Blvd. Claremont, CA 91711.
authors.forename: Julijana
authors.initials: J
authors.lastname: Gjorgjieva
authors.forename: Kelly
authors.initials: K
authors.lastname: Smith
authors.forename: Gerardo
authors.initials: G
authors.lastname: Chowell
authors.forename: Fabio
authors.initials: F
authors.lastname: Sanchez
authors.forename: Jessica
authors.initials: J
authors.lastname: Snyder
authors.forename: Carlos
authors.initials: C
authors.lastname: Castillo-Chavez