Interplay of host and infectious agents.
In this group we would like to answer the question why people show a different response against certain pathogens. In many infections the course of the disease can range from asymptomatic carriage to the severest forms even death. In the past we have analysed candidate genes and their role in the course of malaria and could detect some polymorphisms influencing infectious diseases in the genes encoding NOS2, MBL2, IFNa, FCN2, and receptors for IFNg and IFNa. Having worked initially mainly on malaria we broadened our spectrum also to other infectious diseases like hepatitis B, Leprosy, schistosomiasis. Here we give a short overview about ongoing projects.
Ouf
Eman Abou
EA
Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany.
Bechlars
Silke
S
Böttger
Evelyn
E
Büyükyazici
Birgül
B
Faik
Imad
I
de Carvalho
Elisandra Grangeiro
EG
Meese
Stefanie
S
Oktyabri
Azzaya
A
Ol Opaleye
Oluyinka
O
T P
Velavan
V
Kun
Jürgen F J
JF
D000818:Animals; D003141:Communicable Diseases / Q000276:immunology*; D016207:Cytokines / Q000276:immunology*; D006790:Host-Parasite Interactions / Q000276:immunology*; D006801:Humans; D018448:Models, Immunological
D016207:Cytokines