Highly enantioselective Michael addition of malonates to beta,gamma-unsaturated alpha-ketoesters catalyzed by chiral N,N'-dioxide-Yttrium(III) complexes with convenient procedure.
Highly enantioselective Michael addition of malonates to beta,gamma-unsaturated alpha-ketoesters has been promoted by chiral N,N'-dioxide-Yttrium(iii) complexes, providing the corresponding products in excellent yields with 94-99% ee values.
Zhou
Lin
L
Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.
Lin
Lili
L
Wang
Wentao
W
Ji
Jie
J
Liu
Xiaohua
X
Feng
Xiaoming
X
D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008314:Malonates / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D015019:Yttrium / Q000737:chemistry*
D004952:Esters; D007659:Ketones; D008314:Malonates; D009942:Organometallic Compounds; D015019:Yttrium