title: Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study.
abstract: Although there is ample evidence supporting the effectiveness of physical activity in the prevention and treatment of osteoporosis, there are no previous studies to examine the effect of office-based brief high-impact exercise (HIE) on bone mineral density (BMD) in healthy premenopausal women. This study evaluated the effects of office-based HIE on BMD in healthy premenopausal Japanese women. Ninety-one healthy premenopausal women were randomized to receive stretching exercise (SE) or HIE (stretching, along with up to 5 × 10 vertical and versatile jumps) for 12 months. The BMD of the lumbar spine and proximal femur was measured using dual-energy X-ray absorptiometry. Several cardiovascular risk factors and leg strength also were assessed. An accelerometer-based recorder was used to measure daily impact loading in four 1-week samples. The progression of the HIE program was ensured by the accelerometer. Thirty-three women (71.7%) in the SE group and 34 (75.6%) in the HIE group completed the study. There was a significant difference in the change in the femoral neck BMD between the groups in favor of the HIE group [0.6% (95% CI: -0.4, 1.7) vs. -1.0% (95% CI: -2.2, 0.2)]. Adiponectin, LDL, HDL, and the leg strength of participants in both the groups improved during the intervention. These finding suggested that office-based brief HIE can be recommended for premenopausal women for preventing bone mineral loss.
authors.affiliation: Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
authors.forename: Kaijun
authors.initials: K
authors.lastname: Niu
authors.forename: Riikka
authors.initials: R
authors.lastname: Ahola
authors.forename: Hui
authors.initials: H
authors.lastname: Guo
authors.forename: Raija
authors.initials: R
authors.lastname: Korpelainen
authors.forename: Jin
authors.initials: J
authors.lastname: Uchimaru
authors.forename: Aki
authors.initials: A
authors.lastname: Vainionpää
authors.forename: Kyoko
authors.initials: K
authors.lastname: Sato
authors.forename: Aiko
authors.initials: A
authors.lastname: Sakai
authors.forename: Sinikka
authors.initials: S
authors.lastname: Salo
authors.forename: Koshi
authors.initials: K
authors.lastname: Kishimoto
authors.forename: Eiji
authors.initials: E
authors.lastname: Itoi
authors.forename: Shoko
authors.initials: S
authors.lastname: Komatsu
authors.forename: Timo
authors.initials: T
authors.lastname: Jämsä
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Nagatomi
mesh_terms: D015502:Absorptiometry, Photon; D000054:Acceleration; D000368:Aged; D015519:Bone Density; D015444:Exercise; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging; D006620:Hip Fractures / Q000517:prevention & control; D006801:Humans; D007564:Japan; D010024:Osteoporosis / Q000517:prevention & control; D017697:Premenopause; D011795:Surveys and Questionnaires; D016387:Women's Health; D017132:Workplace