title: Hypervirulent Clostridium difficile strains in hospitalized patients, Canada.
abstract: To determine the incidence rate of infections with North American pulsed-field types 7 and 8 (NAP7/NAP8) strains of Clostrodium difficile, ribotype 078, and toxinotype V strains, we examined data collected for the Canadian Nosocomial Infections Surveillance Program (CNISP) CDI surveillance project during 2004-2008. Incidence of human infections increased from 0.5% in 2004/2005 to 1.6% in 2008.
authors.affiliation: Public Health Agency of Canada, 1015 Arlington St, Winnipeg, Manitoba R3E 3R2, Canada. michael_mulvey@phac-aspc.gc.ca
authors.forename: Michael R
authors.initials: MR
authors.lastname: Mulvey
authors.forename: David A
authors.initials: DA
authors.lastname: Boyd
authors.forename: Denise
authors.initials: D
authors.lastname: Gravel
authors.forename: Jim
authors.initials: J
authors.lastname: Hutchinson
authors.forename: Sharon
authors.initials: S
authors.lastname: Kelly
authors.forename: Allison
authors.initials: A
authors.lastname: McGeer
authors.forename: Dorothy
authors.initials: D
authors.lastname: Moore
authors.forename: Andrew
authors.initials: A
authors.lastname: Simor
authors.forename: Kathryn N
authors.initials: KN
authors.lastname: Suh
authors.forename: Geoff
authors.initials: G
authors.lastname: Taylor
authors.forename: J Scott
authors.initials: JS
authors.lastname: Weese
authors.forename: Mark
authors.initials: M
authors.lastname: Miller
mesh_terms: D000368:Aged; D002170:Canada / Q000453:epidemiology; D016360:Clostridioides difficile / Q000235:genetics / Q000472:pathogenicity*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D005798:Genes, Bacterial / Q000235:genetics; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011159:Population Surveillance; D021521:Ribotyping; D017422:Sequence Analysis, DNA