title: Selective depletion of Sulfolobus solfataricus transcription factor E under heat shock conditions.
abstract: Archaeal transcriptional machinery is similar to that of eukaryotes. We studied the fates of various components of the Sulfolobus solfataricus transcriptional apparatus under different stresses and found that in cells incubated at 90 degrees C for 1 h, transcription factor E (TFE) is selectively depleted, but its mRNA levels are increased. We discuss the implications of these findings.
authors.affiliation: Department of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, Karachi 74800, Pakistan.
authors.forename: Junaid
authors.initials: J
authors.lastname: Iqbal
authors.forename: Sohail A
authors.initials: SA
authors.lastname: Qureshi
mesh_terms: D019843:Archaeal Proteins / Q000235:genetics / Q000378:metabolism*; D015153:Blotting, Western; D019848:Gene Expression Regulation, Archaeal / Q000235:genetics / Q000502:physiology; D006358:Hot Temperature; D016133:Polymerase Chain Reaction; D055550:Protein Stability; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism*; D048229:Sulfolobus solfataricus / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D019843:Archaeal Proteins; D011994:Recombinant Proteins; D014157:Transcription Factors