title: Antibacterial activity of composite resin with glass-ionomer filler particles.
abstract: The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxillary first molars, and plaque accumulation on the resin block surface was examined after 8 hours. For the antibacterial test, the number of Streptococcus mutans in contact with the composite resin blocks after incubation for 12 hours was determined, and adherence of radiolabeled bacteria was evaluated. Less dental plaque was formed on Beautifil II resin block as compared to the other two materials. Antibacterial test revealed that there were no significant differences in the number of Streptococcus mutans among the three composite resins. However, the adherence of radiolabeled bacteria to the saliva-treated resin surface was significantly (p<0.01) lower in Beautifil II than in the other two materials. These results suggested that Beautifil II could reduce dental plaque formation and bacterial adherence, leading to prevention of secondary caries.
authors.affiliation: Department of Operative Dentistry, Division of Oral Functional Sciences and Rehabilitation, Asahi University School of Dentistry, Gifu, Japan.
authors.forename: Seitaro
authors.initials: S
authors.lastname: Saku
authors.forename: Hirotomo
authors.initials: H
authors.lastname: Kotake
authors.forename: Rogelio J
authors.initials: RJ
authors.lastname: Scougall-Vilchis
authors.forename: Shizue
authors.initials: S
authors.lastname: Ohashi
authors.forename: Masato
authors.initials: M
authors.lastname: Hotta
authors.forename: Shinya
authors.initials: S
authors.lastname: Horiuchi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hamada
authors.forename: Kenzo
authors.initials: K
authors.lastname: Asaoka
authors.forename: Eiji
authors.initials: E
authors.lastname: Tanaka
authors.forename: Kohji
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001422:Bacterial Adhesion; D017609:Barium Compounds / Q000737:chemistry / Q000494:pharmacology; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry / Q000494:pharmacology; D015169:Colony Count, Microbial; D003188:Composite Resins / Q000737:chemistry / Q000494:pharmacology*; D003764:Dental Materials / Q000737:chemistry / Q000494:pharmacology*; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D005898:Glass / Q000737:chemistry; D005899:Glass Ionomer Cements / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry / Q000494:pharmacology; D019279:Resin Cements / Q000737:chemistry / Q000494:pharmacology; D012463:Saliva / Q000502:physiology; D012822:Silicon Dioxide / Q000737:chemistry / Q000494:pharmacology; D016037:Single-Blind Method; D013052:Spectrometry, X-Ray Emission; D013295:Streptococcus mutans / Q000254:growth & development; D013499:Surface Properties; D013997:Time Factors; D015040:Zirconium / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D017609:Barium Compounds; C470433:Beautifil composite resin; C112828:Clearfil AP-X; D003188:Composite Resins; D003764:Dental Materials; C444701:Filtek Z250; D005899:Glass Ionomer Cements; D008689:Methacrylates; D019279:Resin Cements; C102738:barium glass filler; D017438:Bisphenol A-Glycidyl Methacrylate; D012822:Silicon Dioxide; D015040:Zirconium; C028541:zirconium oxide