title: [Comprehensive therapeutic protocol of electroacupuncture combined with Chinese herbs and rehabilitation training for treatment of cerebral infarction: a multi-center randomized controlled trial].
abstract: OBJECTIVE
  To evaluate the therapeutic effect of comprehensive therapeutic protocol of electroacupuncture combined with active-blood-and-dissolve-stasis herbs and rehabilitation training for cerebral infarction.
  
  
  METHODS
  A multi-center randomized controlled trial was done, three hundred and twenty cases were divided into four groups: electroacupuncture combined with active-blood and dissolve-stasis herbs and rehabilitation training group (group A), electroacupuncture combined with rehabilitation training group (group B), herbs combined with rehabilitation training group (group C) and rehabilitation training group (group D), 80 cases in each group. The following two groups of acupoints were used alternatively in electroacupuncture treatment: the first group including Vasomotor Area, Jianyu (LI 15), Biguan (ST 31), Hegu (LI 4) and Taichong (LR 3); the second group including Motor Area, Quchi (LI 11), Yanglingquan (GB 34) and Shenshu (BL 23). 20 mL Xiangdan injection and 250 mL 5% glucose injection or 250 mL 0.9% sodium chloride injection were used by intravenous drip in herbs treatment once a day. The rehabilitation training was performed by the professional physical therapist. Each group was treated with corresponding treatment protocol. The therapeutic effect was evaluated by index of the mortality or disability rate 3 months after the onset of disease. The intention to treat analysis (ITT) was used in data.
  
  
  RESULTS
  The mortality or handicap rate 3 months after the onset of disease of four groups were 17.5% (14/80) in group A, 22.5% (18/80) in group B, 40. 0% (32/80) in group C, and 31.3% (25/80) in group D, respectively. The group A has a best therapeutic effect (vs group C, group D, both P<0.05), and there was no adverse event.
  
  
  CONCLUSIONS
  The combined application of electroacupuncture, active-blood and dissolve-stasis herbs and rehabilitation training is a better treatment for cerebral infarction in clinic.
authors.affiliation: Acupuncture Department, TCM Hospital of Guangdong Province, Guang-zhou 510120, China.
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Fu
authors.forename: Yuan qi
authors.initials: Yq
authors.lastname: Guo
authors.forename: Xiao-kai
authors.initials: XK
authors.lastname: Chen
authors.forename: Gang-hui
authors.initials: GH
authors.lastname: Jiang
authors.forename: Qing
authors.initials: Q
authors.lastname: He
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Zhu
authors.forename: Xiu-xin
authors.initials: XX
authors.lastname: Wu
authors.forename: Han-hua
authors.initials: HH
authors.lastname: Luo
authors.forename: Lü-ping
authors.initials: LP
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000534:rehabilitation* / Q000628:therapy; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D015671:Electroacupuncture; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004365:Drugs, Chinese Herbal