title: Biomolecule-directed assembly of binary gold and titanium dioxide nanoparticles.
abstract: We report in this paper a novel strategy for "bottom-up" assembly of two types of metallic and semiconductor nanoparticles. By only using a small biomolecule, coenzyme A, as a "linker" to direct the assembly of metallic gold and semiconductor titanium dioxide nanoparticles, the usual biomolecule-directed system can be greatly simplified. Effects of experimental conditions on the formation of binary nanoparticles are studied. This strategy using single small biomolecule to direct assembly of nanoparticles is proven to be efficient, facile and non-toxic and should be extendable to other building blocks.
authors.affiliation: Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhu
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Chen
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Zhu
authors.forename: Genxi
authors.initials: G
authors.lastname: Li
mesh_terms: D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles; D046529:Microscopy, Electron, Transmission; D014025:Titanium / Q000737:chemistry*
chemical_list: C009495:titanium dioxide; D006046:Gold; D014025:Titanium