[Early rescue intracytoplasmic sperm injection: safe for complete IVF failure].
OBJECTIVE
To evaluate the safety of early rescue intracytoplasmic sperm injection (ICSI) for complete failure of in vitro fertilization (IVF).


METHODS
We conducted early rescue ICSI for 105 conventional IVF cycles and follow-up evaluation of the clinical outcomes.


RESULTS
A total of 64 neonates were born, and no significant differences were found in the sex ratio, birth weight and birth defects.


CONCLUSIONS
Early rescue ICSI can significantly improve the clinical outcome in patients with complete IVF failure, but does not increase the clinical risk.
Zhang
Ning-Yuan
NY
Center of Reproductive Medicine, Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008, China.
Sun
Hai-Xiang
HX
Hu
Ya-Li
YL
Wang
Bin
B
Xu
Zhi-Peng
ZP
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007247:Infertility, Female / Q000628:therapy*; D008297:Male; D049590:Postpartum Period; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D017211:Treatment Failure; D016896:Treatment Outcome