title: Poly(ethylene glycol)-based thiol-ene hydrogel coatings-curing chemistry, aqueous stability, and potential marine antifouling applications.
abstract: Photocured thiol-ene hydrogel coatings based on poly(ethylene glycol) (PEG) were investigated for marine antifouling purposes. By varying the PEG length, vinylic end-group, and thiol cross-linker, a library of hydrogel coatings with different structural composition was efficiently accomplished, with or without ester linkages. The thiol-methacrylate and thiol-allyl systems were evaluated with respect to curing, degradation, as well as antifouling properties. Methacrylate-based systems exhibited homopolymerization, whereas allyl-based systems reacted more selectively through thiol-ene couplings reaction. The ester-free hydrogels elucidated higher hydrolytic stability whereas longer PEG chains accelerated the degradation process. The antifouling properties were evaluated by protein adsorption with Bovine serum albumin (BSA) and bioassays with the marine bacteria, Cobetia marina, and the marine diatom, Amphora coffeaeformis; in all tests, longer PEG lengths improved the antifouling properties.
authors.affiliation: KTH Fibre and Polymer Technology, Teknikringen 56-58, SE-100 44 Stockholm, Sweden.
authors.forename: Pontus
authors.initials: P
authors.lastname: Lundberg
authors.forename: Anouk
authors.initials: A
authors.lastname: Bruin
authors.forename: Job W
authors.initials: JW
authors.lastname: Klijnstra
authors.forename: Andreas M
authors.initials: AM
authors.lastname: Nyström
authors.forename: Mats
authors.initials: M
authors.lastname: Johansson
authors.forename: Michael
authors.initials: M
authors.lastname: Malkoch
authors.forename: Anders
authors.initials: A
authors.lastname: Hult
mesh_terms: D002470:Cell Survival / Q000187:drug effects; D003460:Crystallization / Q000379:methods*; D005240:Feasibility Studies; D006244:Hardness; D020100:Hydrogels / Q000737:chemistry*; D008422:Materials Testing; D011092:Polyethylene Glycols / Q000737:chemistry*; D020560:Proteobacteria / Q000187:drug effects*; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013499:Surface Properties; D014867:Water / Q000737:chemistry*; D014871:Water Microbiology
chemical_list: D020100:Hydrogels; D013438:Sulfhydryl Compounds; D014867:Water; D011092:Polyethylene Glycols