title: Bioactive 2-arylbenzofuran derivatives from Morus wittiorum.
abstract: Investigation of an ethanol extract from the stem bark of Morus wittiorum led to the isolation of five new 2-arylbenzofuran derivatives that were named wittifuran S, wittifuran T, wittifuran V, wittifuran W and wittifuran X (1-5). Structures were determined on the basis of spectroscopic analysis. Two new wittifurans and five previously isolated compounds were assayed for antioxidant and anti-inflammatory activity.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Yong-Xia
authors.initials: YX
authors.lastname: Tan
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.forename: Ruo-Yun
authors.initials: RY
authors.lastname: Chen
authors.forename: De-Quan
authors.initials: DQ
authors.lastname: Yu
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005966:Glucuronidase / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018547:Plant Stems; D051381:Rats
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D001572:Benzofurans; D010936:Plant Extracts; C557239:wittifuran; D005966:Glucuronidase