Initial orthostatic hypotension in the young is attenuated by static handgrip.
Initial orthostatic hypotension is common in children. Isometric handgrip increases arterial pressure, central blood volume, cardiac output, and total peripheral resistance. We show that in 14 subjects with initial orthostatic hypotension, isometric handgrip coupled with standing abolished symptoms of initial orthostatic hypotension and minimized decreases in blood pressure and cardiac output with standing.
Clarke
Debbie A
DA
Department of Pediatrics, The Center for Hypotension, New York Medical College, Valhalla, NY; Department of Physiology, The Center for Hypotension, New York Medical College, Valhalla, NY.
Medow
Marvin S
MS
Department of Pediatrics, The Center for Hypotension, New York Medical College, Valhalla, NY; Department of Physiology, The Center for Hypotension, New York Medical College, Valhalla, NY.
Taneja
Indu
I
Department of Pediatrics, The Center for Hypotension, New York Medical College, Valhalla, NY; Department of Physiology, The Center for Hypotension, New York Medical College, Valhalla, NY.
Ocon
Anthony J
AJ
Department of Physiology, The Center for Hypotension, New York Medical College, Valhalla, NY.
Stewart
Julian M
JM
Department of Pediatrics, The Center for Hypotension, New York Medical College, Valhalla, NY; Department of Physiology, The Center for Hypotension, New York Medical College, Valhalla, NY; Department of Medicine, The Center for Hypotension, New York Medical College, Valhalla, NY. Electronic address: Julian_Stewart@NYMC.edu.
D000293:Adolescent; D001810:Blood Volume; D002302:Cardiac Output; D005260:Female; D018737:Hand Strength; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007024:Hypotension, Orthostatic / Q000503:physiopathology*; D008297:Male; D011187:Posture / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology; D055815:Young Adult