Long-term prescribing of antidepressants in the older population: a qualitative study.
BACKGROUND
High rates of long-term antidepressant prescribing have been identified in the older population.


OBJECTIVE
To explore the attitudes of older patients and their GPs to taking long-term antidepressant therapy, and their accounts of the influences on long-term antidepressant use.


METHODS
Qualitative study using in-depth semi-structured interviews.


METHODS
One primary care trust in North Bradford.


METHODS
Thirty-six patients aged > or =75 years and 10 GPs were interviewed. Patients were sampled to ensure diversity in age, sex, antidepressant type, and home circumstances.


RESULTS
Participants perceived significant benefits and expressed little apprehension about taking long-term antidepressants, despite being aware of the psychological and social factors involved in onset and persistence of depression. Barriers to discontinuation were identified following four themes: pessimism about the course and curability of depression; negative expectations and experiences of ageing; medicine discontinuation perceived by patients as a threat to stability; and passive (therapeutic momentum) and active (therapeutic maintenance) decisions to accept the continuing need for medication.


CONCLUSIONS
There is concern at a public health level about high rates of long-term antidepressant prescribing, but no evidence was found of a drive for change either from the patients or the doctors interviewed. Any apprehension was more than balanced by attitudes and behaviours supporting continuation. These findings will need to be incorporated into the planning of interventions aimed at reducing long-term antidepressant prescribing in older people.
Dickinson
Rebecca
R
School of Healthcare, University of Leeds, Leeds.
Knapp
Peter
P
House
Allan O
AO
Dimri
Vandana
V
Zermansky
Arnold
A
Petty
Duncan
D
Holmes
John
J
Raynor
David K
DK
D000368:Aged; D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001291:Attitude of Health Personnel; D001294:Attitude to Health; D032882:Comprehension; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004644:Emotions; D004739:England; D005194:Family Practice / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data
D000928:Antidepressive Agents