title: [SPECT combined with CT angiography yield better diagnostic accuracy of pulmonary embolism--secondary publication].
abstract: The aim of our study was to perform a prospective study that compared the diagnostic ability of V/Q single photon emission computer tomography (V/Q-SPECT), V/Q-SPECT combined with low-dose computed tomography (CT) and pulmonary multidetector computed tomography(MDCT)-angiography in patients suspected of having pulmonary embolism (PE) using a dedicated combined SPECT/MDCT-scanner. V/Q-SPECT in combination with low-dose CT had a sensitivity of 97% and a specificity of 100%. MDCT angiography had a sensitivity of 68% and a specificity of 100%. We conclude that V/Q-SPECT in combination with low-dose CT without contrast has an excellent diagnostic performance and should be considered the first-line imaging technique in the work-up of PE in most cases.
authors.affiliation: Klinik for Klinisk Fysiologi, Nuklear Medicin & PET, Rigshospitalet, DK-2100 Kobenhavn Ø, Denmark. henrik.gutte@rh.regionh.dk
authors.forename: Henrik
authors.initials: H
authors.lastname: Gutte
authors.forename: Jann
authors.initials: J
authors.lastname: Mortensen
authors.forename: Claus Verner
authors.initials: CV
authors.lastname: Jensen
authors.forename: Camilla Bardram
authors.initials: CB
authors.lastname: Johnbeck
authors.forename: Peter
authors.initials: P
authors.lastname: von der Recke
authors.forename: Claus Leth
authors.initials: CL
authors.lastname: Petersen
authors.forename: Ulrik Sloth
authors.initials: US
authors.lastname: Kristoffersen
authors.forename: Andreas
authors.initials: A
authors.lastname: Kjaer
mesh_terms: D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D055420:Perfusion Imaging; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012123:Pulmonary Ventilation; D011829:Radiation Dosage; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed