Muscle metastasis of low-grade endometrial carcinoma seven years after diagnosis: a case report.
BACKGROUND
Early-stage low-grade endometrial carcinoma has an excellent prognosis. In few cases local relapse and/or distant metastases can occur. We report the muscle as an unusual site of metastasis.


METHODS
A 69-year-old woman underwent surgery for FIGO Stage IA, grade 1 endometrioid adenocarcinoma of the endometrium. After four years she had local relapse without response to chemoradiation, requiring pelvic exanteration. Three years later she was diagnosed with a deltoid muscle metastasis confirmed histologically and bone metastases. After failing hormone therapy, chemotherapy was administered. She died eight months after diagnosis of the bone and muscle metastases.


CONCLUSIONS
Low-risk endometrial carcinoma can behave like a high-risk group. Furthermore, this report describes, to our knowledge, the first case of endometrial carcinoma muscle metastasis.
Oaknin
A
A
Hospital Universitari Vall d'Hebron, Barcelona, Spain. amoaknin@vhebron.net
Barretina
M P
MP
Morilla
I
I
D000368:Aged; D001132:Arm; D018269:Carcinoma, Endometrioid / Q000175:diagnosis / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000556:secondary*; D018482:Muscle, Skeletal; D009364:Neoplasm Recurrence, Local