title: Current treatment and clinical trials in ovarian cancer.
abstract: Although platinum chemotherapy remains the standard treatment for ovarian cancer, recent advances in novel targeted drugs have generated anticipation and excitement. In addition, alternate administration schedules of already established cytotoxics have shown promise in both front line and recurrent disease settings. In this review, we outline the seminal trials that influenced our current management as well as introduce recent trials that have provided intriguing results to aid the understanding of ovarian tumour biology.
authors.affiliation: Royal Marsden Hospital, The Gynecology Unit, Department of Medicine, Sycamore House, Downs Road, Sutton, Surrey SM2 5PT, UK.
authors.forename: Liz Y
authors.initials: LY
authors.lastname: Han
authors.forename: Emma
authors.initials: E
authors.lastname: Kipps
authors.forename: Stan B
authors.initials: SB
authors.lastname: Kaye
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents