[Lacrimal assessment of lg E in cases with allergic conjunctivitis].
OBJECTIVE
To present the study regarding Ig E tears dosation in cases with allergic conjunctivitis.


METHODS
The Ig E tear dosation was done on two study groups--group A with 124 patients presenting allergic conjunctivitis symptoms (58 with seasonal allergic conjunctivitis, 43 with atopic allergic ocular symptoms, 23 treated with olopatadina 0.1% for 10 days) and compare group B consisting of 40 healthy patients (no local or general allergic symptoms) evaluated in the the Ophthalmology Clinic Arad between 2002-2008. The biological material used in the study was that of tears samples. For the determination of Ig E we used ELISA method, HUMAN IMUNO IG E QUANTITATION (Bethyl Laboratoires, Montgomery, TX) test.


RESULTS
Significant statistic high levels of IgE concentration were observed in study group A in patients with allergic seasonal conjunctivitis (331.11 +/- 125.22 ng/ml) and patients with atopic terrain (177.18 +/- 56.70) compared to group B (67.25 +/- 8.89 ng/ml) with healthy patients. In the study group with allergic seasonal conjunctivitis there have been significant diminished IgE levels (71.70 +/- 9.94) after treatment.


CONCLUSIONS
The method of IgE tears dosation proved to be efficient in establishing the ethiology of ocular allergies and in the screening of new cases with allergic conjunctivitis.
Turlea
Magdalena
M
Spitalul Municipal Arad, Sectia Oftalmologie.
Cioca
D P
DP
Mârza
Flavia
F
Turlea
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D015415:Biomarkers / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis* / Q000276:immunology; D007765:Lacrimal Apparatus / Q000737:chemistry / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013666:Tears / Q000737:chemistry / Q000276:immunology*
D015415:Biomarkers; D007073:Immunoglobulin E