title: Serious menstrual bleeding associated with use of TNF alpha blocker: two cases.
abstract: Menstrual disorders associated with the use of TNF alpha blocker have been rarely reported. Herein, we reported two cases aged 31 and 41, presenting with excessive menstrual bleeding occured after adalimumab administration which was subsequently discontinued.
authors.affiliation: Department of Rheumatology, Abant Izzet Baysal University Medical School, Bolu, Turkey. cemalbes@hotmail.com
authors.forename: Cemal
authors.initials: C
authors.lastname: Bes
authors.forename: Mehmet
authors.initials: M
authors.lastname: Soy
mesh_terms: D000068879:Adalimumab; D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects* / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004412:Dysmenorrhea / Q000139:chemically induced* / Q000175:diagnosis; D004958:Estradiol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D012720:Severity of Illness Index; D013167:Spondylitis, Ankylosing / Q000188:drug therapy*; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha; D004958:Estradiol; D000068879:Adalimumab