title: [Clinical, etiological, and therapeutic aspects of febrile convulsions. A review of 325 cases in Yaoundé].
abstract: A prospective study of 325 children with febrile seizures was conducted in 2 hospitals in Yaoundé, from 15 January to 15 December 2008. The proportion of patients with febrile seizures among all admitted patients was 6.1%. The mean age was 24.6 months; the peak age of these patients was 12-17 months. The sex ratio was 1.5. The mean temperature on admission was 39.2 degrees C. There was a family history of febrile seizures in 36.4%. Simple febrile seizures were seen in 58.7% and the complex type in 41.3%. Malaria was the main etiology in 67.7%, followed by upper and lower respiratory tract infection in 14.1% and 9.8%, respectively. Lumbar puncture was performed in all patients. The commonest anticonvulsant used to stop seizures was rectal diazepam in 88%. Febrile seizure prophylaxis was administered to 43% of the patients; antipyretics were the most widely used, either alone or combined with rectal diazepam.
authors.affiliation: Département de pédiatrie, faculté de médecine et des sciences biomédicales de l'université de Yaoundé-I, BP 6222, Yaoundé, Caméroun. seraphin_nguefack@yahoo.fr
authors.forename: S
authors.initials: S
authors.lastname: Nguefack
authors.forename: C A
authors.initials: CA
authors.lastname: Ngo Kana
authors.forename: E
authors.initials: E
authors.lastname: Mah
authors.forename: C
authors.initials: C
authors.lastname: Kuate Tegueu
authors.forename: A
authors.initials: A
authors.lastname: Chiabi
authors.forename: F
authors.initials: F
authors.lastname: Fru
authors.forename: P F
authors.initials: PF
authors.lastname: Tchokoteu
authors.forename: E
authors.initials: E
authors.lastname: Mbonda
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002163:Cameroon; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003975:Diazepam / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D008288:Malaria / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D055502:Secondary Prevention; D003294:Seizures, Febrile / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D012737:Sex Factors
chemical_list: D018712:Analgesics, Non-Narcotic; D000927:Anticonvulsants; D003975:Diazepam