Studying the co-evolution of protein families with the Mirrortree web server.
CONCLUSIONS
The Mirrortree server allows to graphically and interactively study the co-evolution of two protein families, and investigate their possible interactions and functional relationships in a taxonomic context. The server includes the possibility of starting from single sequences and hence it can be used by non-expert users.


METHODS
The web server is freely available at http://csbg.cnb.csic.es/mtserver. It was tested in the main web browsers. Adobe Flash Player is required at the client side to perform the interactive assessment of co-evolution.


BACKGROUND
pazos@cnb.csic.es


BACKGROUND
Supplementary data are available at Bioinformatics online.
Ochoa
David
D
National Centre for Biotechnology, Computational Systems Biology Group (CNB-CSIC), c/ Darwin, 3. Cantoblanco, 28049 Madrid, Spain.
Pazos
Florencio
F
D030562:Databases, Protein; D019143:Evolution, Molecular; D020407:Internet; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein; D012984:Software; D014584:User-Computer Interface
D011506:Proteins