title: [Evaluation of the mutagenicity of detergents by tests on bacteria, plant cells and human leucocytes.].
abstract: The aim of this study was to evaluate the mutagenicity of several traditional detergents and that of newer more biodegradable detergents, by using a bacterial test (Ames test), a plant cell test (Allium cepa micronuclei test) and a human leucocyte test (Comet test). All tests were conducted using a wide range of doses (1-2000 mg/l). None of the examined detergents induced mutations in S.typhimurium. One traditional detergent showed a genotoxic effect with the A. cepa test, while all newer detergents and one traditional detergent were shown by the Comet test to be capable of inducing DNA damage.
authors.affiliation: Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Igiene, Epidemiologia e Sanità Pubblica, Università degli Studi di Brescia.
authors.forename: Donatella
authors.initials: D
authors.lastname: Feretti
authors.forename: Roberta
authors.initials: R
authors.lastname: Pedrazzani
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Ceretti
authors.forename: Ilaria
authors.initials: I
authors.lastname: Zerbini
authors.forename: Eleonora
authors.initials: E
authors.lastname: Gozio
authors.forename: Caterina
authors.initials: C
authors.lastname: Belotti
authors.forename: Carlotta
authors.initials: C
authors.lastname: Alias
authors.forename: Francesco
authors.initials: F
authors.lastname: Donato
authors.forename: Umberto
authors.initials: U
authors.lastname: Gelatti
mesh_terms: D001419:Bacteria; D003902:Detergents; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens; D059828:Plant Cells; D012486:Salmonella typhimurium / Q000187:drug effects
chemical_list: D003902:Detergents; D009153:Mutagens