title: [Early rescue intracytoplasmic sperm injection: safe for complete IVF failure].
abstract: OBJECTIVE
  To evaluate the safety of early rescue intracytoplasmic sperm injection (ICSI) for complete failure of in vitro fertilization (IVF).
  
  
  METHODS
  We conducted early rescue ICSI for 105 conventional IVF cycles and follow-up evaluation of the clinical outcomes.
  
  
  RESULTS
  A total of 64 neonates were born, and no significant differences were found in the sex ratio, birth weight and birth defects.
  
  
  CONCLUSIONS
  Early rescue ICSI can significantly improve the clinical outcome in patients with complete IVF failure, but does not increase the clinical risk.
authors.affiliation: Center of Reproductive Medicine, Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008, China.
authors.forename: Ning-Yuan
authors.initials: NY
authors.lastname: Zhang
authors.forename: Hai-Xiang
authors.initials: HX
authors.lastname: Sun
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Hu
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Zhi-Peng
authors.initials: ZP
authors.lastname: Xu
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007247:Infertility, Female / Q000628:therapy*; D008297:Male; D049590:Postpartum Period; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D017211:Treatment Failure; D016896:Treatment Outcome