[The diagnosis and treatment of duodenal lipoma.].
OBJECTIVE
To summarize the clinical features of the duodenal lipomas in order to explore effective diagnostic methods and appropriate treatment preoperatively.


METHODS
The clinical features, laboratory results, endoscopic appearance, radiological and pathological data of 8 cases of duodenal lipoma were retrospectively analyzed.


RESULTS
Four patients suffered with repeated melena, 3 cases with epigastric discomfort, sour regurgitation or hiccup, while 1 patient without any symptoms. Liver functions, serum lipids and tumor markers were normal in all patients. Six patients had been detected lesions by gastroscopy (2 cases missed diagnosed in the first examination), these lesions were appeared in duodenal bulb (2 cases) or descendant duodenum (4 cases). Abdominal CT examination revealed partial duodenal wall thickening (6 cases), partial enteric cavity narrowing (4 cases), or low-density lesions in enteric cavity (3 cases) with CT value of -85 HU and evenly intensified when enhanced. EUS showed intensive hyperechoic lesions from submucosa, with homogeneous echo and clear margin. Biopsy under endoscopy in all patients showed chronic inflammation of mucosa, while the pathologic diagnosis was lipoma after surgical excision or endoscopic resection. Pancreaticoduodenectomy performed in 1 patient, duodenal tumorectomy in 3 patients and endoscopic resection with snare in 4 patients.


CONCLUSIONS
Common site of duodenal lipoma is descending part, and the clinical manifestations are non-specific. Imaging and endoscopic examination are the mainly methods to detect the lesion, while EUS is significantly valuable in diagnosing and differential diagnosing. It can be treated by partial tumorectomy or endoscopic trap resection.
Chen
Hong-Tan
HT
Department of Gastroenterology, the First Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310003, China. Email: chenhongtan@163.com.
Xu
Guo-Qiang
GQ
Wang
Li-Jun
LJ
Yu
Wei-Hua
WH
Zhou
Yi-Feng
YF
Li
You-Ming
YM
D003937:Diagnosis, Differential; D005773:Gastroscopy; D006801:Humans; D008067:Lipoma; D012189:Retrospective Studies