title: Decreasing central line associated bloodstream infection in neonatal intensive care.
abstract: Central Line Associated Bloodstream Infections (CLABSIs) have come to be recognized as preventable adverse events that result from lapses in technique at multiple levels of care. CLABSIs are associated with increased mortality and adverse outcomes that may have lifelong consequences. This review provides a summary of evidence-based strategies to reduce CLABSI in the newborn intensive care unit that have been described in the literature over the past decades. Implementation of these strategies in "bundles" is also discussed, citing examples of successful quality improvement collaboratives. The methods of implementation require an understanding of the scientific data and technical developments, as well as knowledge of how to influence change within the unique and complicated milieu of the newborn intensive care unit.
authors.affiliation: Good Samaritan Hospital, Newborn Intensive Care Unit, Pediatrix Neonatology Medical Group of San Jose, 3880 South Bascom Avenue, Suite 208, San Jose, CA 95124, USA. richard_powers@pediatrix.com
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Powers
authors.forename: David W
authors.initials: DW
authors.lastname: Wirtschafter
mesh_terms: D016470:Bacteremia / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D001419:Bacteria / Q000302:isolation & purification; D055499:Catheter-Related Infections / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D003428:Cross Infection / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D006225:Hand / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007363:Intensive Care Units, Neonatal; D011785:Quality Assurance, Health Care