Design and an efficient synthesis of new thiorotenone derivatives.
A series of novel 4-aryl-thiopyrano[3,4-b]pyran-5-one derivatives were synthesized through an efficient one-pot three-component reaction under solvent-free conditions. This work provides a new series of derivatives of thiorotenone with potential biological activity for biomedical screening.
Yao
Changsheng
C
School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China.
Wang
Cuihua
C
Jiang
Bei
B
Feng
Xiaodong
X
Yu
Chenxia
C
Li
Tuanjie
T
Tu
Shujiang
S
D018360:Crystallography, X-Ray; D015195:Drug Design; D008968:Molecular Conformation; D012402:Rotenone / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
D012402:Rotenone