Matrix metalloproteinases are elevated in the urine of patients with endometriosis.
In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected in the urine of patients with endometriosis than in controls.
Becker
Christian M
CM
Frauenklinik und Geburtshilfe, Charité, Universitätsklinikum Benjamin Franklin, Berlin, Germany. christian.becker@obs-gyn.ox.ac.uk
Louis
Gwendolyn
G
Exarhopoulos
Alexis
A
Mechsner
Sylvia
S
Ebert
Andreas D
AD
Zurakowski
David
D
Moses
Marsha A
MA
D000328:Adult; D015415:Biomarkers / Q000378:metabolism / Q000652:urine; D016022:Case-Control Studies; D004715:Endometriosis / Q000201:enzymology / Q000378:metabolism / Q000652:urine*; D005260:Female; D006801:Humans; D020778:Matrix Metalloproteinase 2 / Q000652:urine; D020780:Matrix Metalloproteinase 9 / Q000652:urine; D020782:Matrix Metalloproteinases / Q000378:metabolism / Q000652:urine*; D015854:Up-Regulation; D014591:Uterine Diseases / Q000201:enzymology / Q000378:metabolism / Q000652:urine*
D015415:Biomarkers; D020782:Matrix Metalloproteinases; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9