title: Relationship between cardiovascular function and fetal growth restriction in women with pre-eclampsia.
abstract: OBJECTIVE
  To investigate the relationship between cardiovascular function in women with pre-eclampsia and fetal growth restriction (FGR) using impedance cardiography.
  
  
  METHODS
  This retrospective study was performed with 639 participants allocated to one of 4 groups, a pre-eclampsia (PE) with FGR group, a PE without FGR group, a pregnancy-induced hypertension (PIH) without FGR group, and normal pregnancy (NP) group. Hemodynamic monitoring was performed noninvasively using impedance cardiography.
  
  
  RESULTS
  Mean arterial pressure and peripheral resistance were significantly higher, and cardiac output and maternal systolic function were significantly lower, in the 2 PE groups than in the PIH and NP groups, and these differences were the greatest between the NP and the PE with FGR groups.
  
  
  CONCLUSIONS
  Impedance cardiography allowed to observe a gradual increase in peripheral resistance and cardiac output from the NP group to the PIH, the PE without FGR, and the PE with FGR groups. The most reduced systolic function and cardiac output and the most increased peripheral resistance was observed in the PE with FGR group.
authors.affiliation: Department of Obstetrics, Nanjing Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Nanjing, China.
authors.forename: Rui-zhe
authors.initials: RZ
authors.lastname: Jia
authors.forename: Xiao-mei
authors.initials: XM
authors.lastname: Liu
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Hai-qing
authors.initials: HQ
authors.lastname: Wu
mesh_terms: D000328:Adult; D001794:Blood Pressure; D002302:Cardiac Output; D002307:Cardiography, Impedance / Q000379:methods; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D012189:Retrospective Studies; D014655:Vascular Resistance; D055815:Young Adult