title: Nucleobase-containing peptides: an overview of their characteristic features and applications.
abstract: Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many areas of biology and therapy are taken into critical consideration.
authors.affiliation: Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Via Mezzocannone 16, 80134, Naples, Italy.
authors.forename: Giovanni N
authors.initials: GN
authors.lastname: Roviello
authors.forename: Ettore
authors.initials: E
authors.lastname: Benedetti
authors.forename: Carlo
authors.initials: C
authors.lastname: Pedone
authors.forename: Enrico M
authors.initials: EM
authors.lastname: Bucci
mesh_terms: D004247:DNA / Q000737:chemistry; D006801:Humans; D009705:Nucleosides; D010455:Peptides / Q000737:chemistry / Q000627:therapeutic use; D012313:RNA / Q000737:chemistry
chemical_list: D009705:Nucleosides; D010455:Peptides; D012313:RNA; D004247:DNA