Pulmonary metastatic calcification in a leukemic patient: a case report.
Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in children and accounts for 80% to 85% of cases. Hypercalcemia-associated pulmonary calcification has been observed in ALL, but overall it is a rare condition. Hereby, we wanted to report a case of pulmonary metastatic calcification in a 4-year-old girl with diagnosis of ALL in our center, who died 1 year after diagnosis of leukemia. Pulmonary infiltrates were seen 2 months after diagnosis of leukemia, which was proved to be the flecks of calcium in alveolar spaces after open-lung biopsy performed 4 months after diagnosis of ALL, but elevated serum calcium was detected late in the course of the disease (7 mo after lung biopsy), this late occurrence of hypercalcemia is not reported yet.
Izadyar
Mina
M
Departments of Pediatric Hematology, Tehran University of Medical Sciences, Markaze Tebbi Koodakan (Children Medical Center), Tehran, Iran.
Mahjoub
Fatemeh
F
Ardakani
Soodeh Nili
SN
Ahmadi
Javad
J
D002114:Calcinosis; D002118:Calcium / Q000378:metabolism*; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000473:pathology*; D011379:Prognosis
D002118:Calcium