title: NW-G01, a novel cyclic hexapeptide antibiotic, produced by Streptomyces alboflavus 313: II. Structural elucidation.
abstract: NW-G01 is a novel cyclic hexapeptide antibiotic produced by Streptomyces alboflavus 313. Its relative structure was established by HR-ESI-MS, IR, 1D and 2D NMR techniques, the absolute structure was determined using a combination of single-crystal X-ray diffraction and Marfey's method finally. The antibiotic consists of L-valine, (3S)- and (3R)-piperazic acids, N-methyl-D-alanine and (2S,3aR,8aS)-6-chloro-3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid.
authors.affiliation: Institute of Pesticide Science, Northwest Agricultural & Forestry University, Shaanxi, China.
authors.forename: Zhengyan
authors.initials: Z
authors.lastname: Guo
authors.forename: Zhiqin
authors.initials: Z
authors.lastname: Ji
authors.forename: Jiwen
authors.initials: J
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Deng
authors.forename: Ling
authors.initials: L
authors.lastname: Shen
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Wenjun
authors.initials: W
authors.lastname: Wu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D047630:Depsipeptides / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism; D013302:Streptomyces / Q000378:metabolism; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D047630:Depsipeptides; C544293:NW-G01