title: Bulk modulus and volume variation measurement of the liver and the kidneys in vivo using abdominal kinetics during free breathing.
abstract: This article presents a method of predictive simulation, patient-dependant, in real time of the abdominal organ positions during free breathing. The method, that considers both influence of the abdominal breathing and thoracic breathing, needs a tracking of the patient skin and a model of the patient-specific modification of the diaphragm shape. From a measurement of the abdomen viscera kinematic during free breathing, we evaluate through a finite element analysis, the stress field sustained by the organs for a hyperelastic mechanical behaviour using large strain theory. From this analysis, we deduce an in vivo Poisson's ratio and a homogeneous bulk modulus of the liver and kidneys, and compare it to the ones in vitro available in the literature.
authors.affiliation: Institut de Mécanique des Fluides et des Solides, Université de Strasbourg, CNRS, 2 rue boussingault, F-67000 Strasbourg, Alsace, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Hostettler
authors.forename: Daniel
authors.initials: D
authors.lastname: George
authors.forename: Yves
authors.initials: Y
authors.lastname: Rémond
authors.forename: Stéphane André
authors.initials: SA
authors.lastname: Nicolau
authors.forename: Luc
authors.initials: L
authors.lastname: Soler
authors.forename: Jacques
authors.initials: J
authors.lastname: Marescaux
mesh_terms: D000005:Abdomen / Q000033:anatomy & histology / Q000502:physiology*; D001696:Biomechanical Phenomena; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D012119:Respiration; D014057:Tomography, X-Ray Computed