title: High output cardiac failure in a parturient with hereditary haemorrhagic telangiectasia.
abstract: Hereditary haemorrhagic telangiectasia is a genetic condition which results in arteriovenous malformations involving the skin, mucous membranes, lung, brain, gastrointestinal tract, liver and spinal canal. The shunting of blood through arteriovenous malformations, especially in the liver,; leads to maldistribution of cardiac output. In order to supply blood to vital organs, cardiac output is increased through vasodilation, elevated stroke volume and elevated heart rate. Pregnancy can worsen the effects of the arteriovenous malformations. We present the peripartum management of a woman with hereditary haemorrhagic telangiectasia predominantly involving the liver that resulted in high output cardiac failure during two consecutive pregnancies.
authors.affiliation: Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia. chungfeilai@gmail.com
authors.forename: C F
authors.initials: CF
authors.lastname: Lai
authors.forename: A
authors.initials: A
authors.lastname: Dennis
authors.forename: J
authors.initials: J
authors.lastname: Graham
mesh_terms: D000328:Adult; D016534:Cardiac Output, High / Q000209:etiology*; D017548:Echocardiography, Transesophageal; D005260:Female; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D011247:Pregnancy; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000000981:diagnostic imaging