title: [The role of melatonin in the development of psychosomatic diseases].
abstract: Relationship between psychic and somatic disorders is currently a most widely discussed problem. The published results of relevant research reflect controversial views of internists and psychiatrists. The aim of this paper is to elucidate common mechanisms underlying some psychosomatic diseases based on the chronobiological approach with special reference to abnormal production of melatonin (main rhythm-controlling hormone) resulting in the disturbance of biological rhythms (desynchronosis). Different scenarios of development of psychosomatic disorders are considered using models of irritated bowel syndrome and ulcer disease.
authors.forename: D B
authors.initials: DB
authors.lastname: Kolesnikov
authors.forename: L A
authors.initials: LA
authors.lastname: Voznesenskaia
authors.forename: S I
authors.initials: SI
authors.lastname: Rapoport
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology; D006801:Humans; D008550:Melatonin / Q000502:physiology*; D011602:Psychophysiologic Disorders / Q000378:metabolism*
chemical_list: D008550:Melatonin