title: Enantioselective alpha-amination of 1,3-dicarbonyl compounds using squaramide derivatives as hydrogen bonding catalysts.
abstract: Catalytic enantioselective alpha-hydrazination of 1,3-dicarbonyl compounds with azodicarboxylates was investigated in the presence of our newly developed hydrogen bonding catalyst, squaramide 3j. High yields and high enantioselectivities were achieved with low catalyst loading under mild conditions.
authors.affiliation: Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Konishi
authors.forename: Tin Yiu
authors.initials: TY
authors.lastname: Lam
authors.forename: Jeremiah P
authors.initials: JP
authors.lastname: Malerich
authors.forename: Viresh H
authors.initials: VH
authors.lastname: Rawal