title: A novel subclassification for Kunitz proteinase inhibitors from leguminous seeds.
abstract: Kunitz-type trypsin inhibitors from legume seeds have been characterized structurally. The presence of Cys-Cys in single or double chains shows a new pattern of proteins structurally not so closely related to STI. Therefore, briefly, with regard to cysteine content, plant Kunitz proteinase inhibitors may be classified into four groups: no Cys-Cys at all, one, two and more than two Cys residues. Functional properties and diversity of these proteins are also briefly discussed.
authors.affiliation: Department of Biochemistry, Universidade Federal de São Paulo-Escola Paulista de Medicina, São Paulo, Brazil. olivaml.bioq@epm.br
authors.forename: Maria Luiza V
authors.initials: ML
authors.lastname: Oliva
authors.forename: Mariana C C
authors.initials: MC
authors.lastname: Silva
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Sallai
authors.forename: Marlon V
authors.initials: MV
authors.lastname: Brito
authors.forename: Misako U
authors.initials: MU
authors.lastname: Sampaio
mesh_terms: D000595:Amino Acid Sequence; D003545:Cysteine; D007887:Fabaceae; D006801:Humans; D008969:Molecular Sequence Data; D010447:Peptide Hydrolases / Q000378:metabolism*; D010455:Peptides / Q000737:chemistry / Q000145:classification* / Q000378:metabolism; D010940:Plant Proteins / Q000737:chemistry / Q000145:classification* / Q000378:metabolism; D011487:Protein Conformation; D012639:Seeds
chemical_list: C053865:Kunitz-type protease inhibitor, plant; D010455:Peptides; D010940:Plant Proteins; D010447:Peptide Hydrolases; D003545:Cysteine