title: Rosai-Dorfman disease manifesting as a mediastinal mass with calcifications.
abstract: Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease, is a rare entity predominantly affecting children and young adults, characterized in 95% of patients by painless bilateral cervical limphadenopathy. We report the case of a 30-year-old female with an anterior mediastinal mass due to lymph node enlargement, which showed calcifications on computed tomography. To our knowledge, calcification in lymphadenopathy, as is present in this case, has never been described in Rosai-Dorfman disease.
authors.affiliation: Clínica Universitária de Imagiologia, Hospitais da Universidade de Coimbra, Portugal. jbmbrito@gmail.com
authors.forename: Jorge
authors.initials: J
authors.lastname: Brito
authors.forename: Vítor
authors.initials: V
authors.lastname: Sousa
authors.forename: Luísa
authors.initials: L
authors.lastname: Teixeira
authors.forename: Lina
authors.initials: L
authors.lastname: Carvalho
authors.forename: Filipe
authors.initials: F
authors.lastname: Caseiro-Alves
mesh_terms: D000328:Adult; D001706:Biopsy; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media