[Clinical implication of stone culture in percutaneous nephrolithotomy].
OBJECTIVE
To evaluate the correlation between stone culture and SIRS, ascertain the clinical implication of stone culture in PCNL.


METHODS
Clinical data of 66 patients who underwent PCNL in our department were analyzed retrospectively. Eight risk factors including stone culture + drug sensitivity, urine culture + drug sensitivity, age, gender, prophylactic antibiotics, stone volume, operative time and the number of tract. Multiple statistics methods were used for analysis to evaluate the impact of SIRS, and compare the difference between stone culture and urine culture.


RESULTS
Univariate analysis and Multivariate logistic regression model showed that positive stone culture was the risk factor of SIRS (P < 0.05). Positive stone culture was found in 48.48% patients, which was higher than that of urine culture (30.30%). Fourteen patients (66.67%) of 21 postoperative SIRS patients were prescribed antibiotics according to the stone culture result. And all of them recovered unevenly without developing septic shock or MODS.


CONCLUSIONS
Positive stone culture is the important risk factor of post-PCNL SIRS. Stone culture is better than urine culture in directing postoperative antibiotics prescripsion and should be routinely used.
Ma
Kai
K
Department of Urology, Peking University People's Hospital, Beijing 100034, China.
Xu
Qing-Quan
QQ
Huang
Xiao-Bo
XB
Wang
Xiao-Feng
XF
Li
Jian-Xing
JX
Xiong
Liu-Lin
LL
Yang
Bo
B
Ye
Xiong-Jun
XJ
Na
Yan-Qun
YQ
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000382:microbiology*; D016015:Logistic Models; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015999:Multivariate Analysis; D009403:Nephrostomy, Percutaneous / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology* / Q000382:microbiology; D055815:Young Adult