An Enantioselective Synthesis of the ABD Tricycle for (-)-Phomactin A Featuring Rawal's Asymmetric Diels-Alder Cycloaddition.
An enantioselective synthesis of the ABD-ring of (-)-phomactin A is described here. The sequence features Rawal's asymmetric Diels-Alder cycloaddition. The overall length is significantly reduced from our previous attempt.
You
Ling-Feng
LF
Division of Pharmaceutical Sciences and Department of Chemistry, Rennebohm Hall, 777 Highland Avenue, University of Wisconsin, Madison, WI 53705, rhsung@wisc.edu and cole_kevin_p_phd@lilly.com.
Hsung
Richard P
RP
Bedermann
Aaron A
AA
Kurdyumov
Aleksey V
AV
Tang
Yu
Y
Buchanan
Grant S
GS
Cole
Kevin P
KP