Hydrogen-bonding controls the solid-state and enantiomeric conformations of the amino alcohol ligand 2-[(2-hydroxyethyl)amino]cyclohexanol.
The crystal structure of the title compound, C(8)H(17)NO(2), consists of (R,R) and (S,S) enantiomeric pairs packed in adjacent double layers which are characterized by centrosymmetric hydrogen-bonded dimers, generated via N-H...O and O-H...O interactions, respectively. Intermolecular interactions, related to acceptor and donor molecule chirality, link the achiral double layers into tubular columns, which consist of a staggered hydrophilic inner core surrounded by a hydrophobic cycloalkyl outer surface and extend in the [011] direction.
de Sousa
Alvaro S
AS
School of Chemistry, Molecular Sciences Institute, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa. alvaro.desousa@wits.ac.za
Hlam
Zanele
Z
Fernandes
Manuel A
MA
Marques
Helder M
HM