title: Blue rubber bleb nevus syndrome with late onset of central nervous system symptomatic involvement.
abstract: Blue rubber bleb nevus syndrome is a rare vascular disorder characterized by cavernous angiomas of skin and other organs including the gastrointestinal tract. The central nervous system involvement is seldom reported, and neurological symptoms at onset in adulthood are extremely rare. Here, we describe a case of 82-year-old patient presenting multiple skin haemangiomas for some years, who was admitted for a brain hemorrhage. The MRI demonstrated the presence of multiple cavernous angiomas within the cerebral tissue.
authors.affiliation: Unità Operativa Di Neurologia, Azienda Ospedaliera-Universitaria, Verona, Italy. giampaolo.tomelleri@azosp.vr.it
authors.forename: Giampaolo
authors.initials: G
authors.lastname: Tomelleri
authors.forename: Manuel
authors.initials: M
authors.lastname: Cappellari
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Matteo
authors.forename: Tiziano
authors.initials: T
authors.lastname: Zanoni
authors.forename: Chiara
authors.initials: C
authors.lastname: Colato
authors.forename: Paolo
authors.initials: P
authors.lastname: Bovi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Moretto
mesh_terms: D000369:Aged, 80 and over; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000473:pathology*; D017809:Fatal Outcome; D020786:Hemangioma, Cavernous, Central Nervous System / Q000150:complications* / Q000473:pathology*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D018329:Nevus, Blue / Q000150:complications* / Q000473:pathology*; D012867:Skin / Q000473:pathology; D020521:Stroke / Q000150:complications; D014057:Tomography, X-Ray Computed