[Proliferation markers used in histological studies].
The present paper reviews the current approaches used to study cell proliferative activity. In the last years, a number of proteins involved in cell cycle control were discovered, that may serve as selective markers of proliferating cells. This work gives the characteristics of immunocytochemical methods demonstrating 5-bromodeoxyuridine, PCNA, Ki-67, FEN-1, phosphorylated histone H3 and cyclins. The data on the role of these proteins in cell cycle control are presented.
Kirik
O V
OV
Beznin
G V
GV
Korzhevskiĭ
D E
DE
D000818:Animals; D015415:Biomarkers / Q000032:analysis; D001973:Bromodeoxyuridine / Q000032:analysis; D049109:Cell Proliferation; D016213:Cyclins / Q000032:analysis; D007150:Immunohistochemistry; D009687:Nuclear Proteins / Q000032:analysis
D015415:Biomarkers; D016213:Cyclins; D009687:Nuclear Proteins; D001973:Bromodeoxyuridine