A selective electrochemical method of glycosylation of 3beta-hydroxy-Delta 5-steroids.
A new electrochemical glycosylation method is presented. According to the method cholesterol and other 3beta-hydroxy-Delta(5)-steroids can be selectively transformed to glycosides using non-activated sugars. The method is also useful for the synthesis of glycoconjugates with sugar linked to a steroid moiety by an ether bond.
Morzycki
Jacek W
JW
Institute of Chemistry, University of Białystok, Piłsudskiego 11/4, 15-443 Białystok, Poland. morzycki@uwb.edu.pl
Łotowski
Zenon
Z
Siergiejczyk
Leszek
L
Wałejko
Piotr
P
Witkowski
Stanisław
S
Kowalski
Jan
J
Płoszyńska
Jolanta
J
Sobkowiak
Andrzej
A
D004563:Electrochemistry / Q000379:methods*; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry*; D006031:Glycosylation; D015394:Molecular Structure; D013256:Steroids / Q000737:chemistry*
D006027:Glycosides; D013256:Steroids