Highly effective treatment with tacrolimus ointment in an adolescent with oral graft-versus-host disease.
METHODS
We report a case of acute oral graft-versus-host disease in an adolescent, which was successfully treated with tacrolimus 0.1% ointment.


CONCLUSIONS
Although tacrolimus ointment is not licensed for the indication of oral GvHD, this case report provides preliminary evidence for a potential effectiveness of using tacrolimus in case of failure when GvHD is resistant.
Bauters
T
T
Department of Pharmacy, Ghent University Hospital, -1 K12, De Pintelaan 185, 9000, Ghent, Belgium. tiene.bauters@uzgent.be
Bordon
V
V
Van de Velde
V
V
Van Lancker
S
S
Robays
H
H
Benoit
Y
Y
Laureys
G
G
D000293:Adolescent; D006086:Graft vs Host Disease / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology*; D009824:Ointments; D016559:Tacrolimus / Q000008:administration & dosage*; D014059:Tongue / Q000473:pathology; D014060:Tongue Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
D009824:Ointments; D016559:Tacrolimus