title: Functional outcome of orthotopic bladder substitution: a comparison between the S-shaped and U-shaped neobladder.
abstract: OBJECTIVE
  To compare the functional outcome of two types of orthotopic bladder substitution, the S-shaped and the U-shaped neobladder, with respect to leakage, functional capacity and quality of life.
  
  
  METHODS
  Between 1999 and 2007, 45 male patients with urinary bladder cancer were treated with cystectomy and orthotopic bladder substitution; 23 with the S-shaped bladder ad modum Schreiter and 22 with the U-shaped bladder ad modum Studer. Patients were followed up by a urologist and a specialized nurse (urotherapist) at 1, 3 and 6 months. At each visit the patient completed a voiding chart, a weighted pad test and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Differences between the groups in functional outcome and quality of life variables were analysed by Student's t test using SPSS software.
  
  
  RESULTS
  Mean maximum bladder capacity increased over time. At 6 months, the S-bladder had a larger capacity than the U-bladder (525 ml vs 423 ml). Patients with an S-bladder had less urine leakage at all follow-ups, although this was statistically significant only at 6 months regarding day-time incontinence and at all visits regarding night-time incontinence. The mean urine leakage at 6 months was 7 g (day) and 30 g (night) in the S-bladder group and 50 g (day) and 250 g (night) in the U-bladder group. However, quality of life did not differ between the groups.
  
  
  CONCLUSIONS
  The S-bladder had better bladder capacity and less leakage than the U-bladder, but these differences did not translate into differences in quality of life. The results should be confirmed in larger prospective studies.
authors.affiliation: Department of Urology, Orebro University Hospital, Orebro, Sweden. tomas.jerlstrom@orebroll.se
authors.forename: Tomas
authors.initials: T
authors.lastname: Jerlström
authors.forename: Gunnel
authors.initials: G
authors.lastname: Andersson
authors.forename: Malcolm
authors.initials: M
authors.lastname: Carringer
mesh_terms: D000368:Aged; D053715:Cystotomy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D053206:Nocturnal Enuresis / Q000453:epidemiology; D009989:Orthotic Devices; D015995:Prevalence; D011468:Prostatectomy; D019736:Prostheses and Implants; D011474:Prosthesis Design; D011788:Quality of Life; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000502:physiology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000601:surgery*