title: [Use of reamberin for correction of enterocyte functional activity in experimental disseminated purulent peritonitis].
abstract: Violation of the structural integrity and functional activity of mitochondria in the muscular coat of small intestine is among the main factors responsible for enteroparesis under conditions of widespread purulent peritonitis. This morphofunctional disorder leads to a sharp decrease in ATP synthesis, which is directly related to a low electric activity of parts of the small intestine. The drug reamberin that contains succinic acid favors elimination of the dysfunction of enterocyte mitochondria and restoration of the intestinal motility under conditions of widespread purulent peritonitis.
authors.forename: V A
authors.initials: VA
authors.lastname: Kosinets
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D000818:Animals; D020895:Enterocytes / Q000187:drug effects* / Q000502:physiology; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008928:Mitochondria / Q000378:metabolism / Q000648:ultrastructure; D009130:Muscle, Smooth / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D010538:Peritonitis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D011817:Rabbits; D019802:Succinic Acid / Q000627:therapeutic use*; D013492:Suppuration
chemical_list: D000255:Adenosine Triphosphate; D019802:Succinic Acid