Isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil.
From a petroleum ether extract of neem oil (Azadirachta indica A. Juss) the new tetrahydrofuranyl diester 1 was isolated as an anti-bacterial constituent. 1 showed significant activities against three standard bacterial strains, including Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 and Salmonella enteritidis CMCC (B) 50041.
Zhang
Yu-Qun
YQ
College of Animal Medicine, Sichuan Agricultural University, Ya'an, 625014, PR China.
Xu
Jiao
J
Yin
Zhong-Qiong
ZQ
Jia
Ren-Yong
RY
Lu
Yang
Y
Yang
Fan
F
Du
Yong-Hua
YH
Zou
Ping
P
Lv
Cheng
C
Hu
Ting-Xiu
TX
Liu
Shu-Liang
SL
Shu
Gang
G
Yi
Geng
G
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D031601:Azadirachta / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects*; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology; D005989:Glycerides / Q000737:chemistry / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D012477:Salmonella enteritidis / Q000187:drug effects*; D012639:Seeds; D013211:Staphylococcus aureus / Q000187:drug effects*; D013229:Stearic Acids / Q000302:isolation & purification* / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005663:Furans; D005989:Glycerides; D010938:Plant Oils; D013229:Stearic Acids; D013729:Terpenes; C557240:m-octadecanoic acid-3,4-tetrahydrofuran diester; C002443:neem oil