title: Insular epilepsy masquerading as multifocal cortical epilepsy as proven by depth electrode.
abstract: The insular cortex is an uncommon epileptogenic location from which complex partial seizures may arise. Seizure activity in insular epilepsy may mimic temporal, parietal, or other cortical areas. Semiology, electroencephalography, and even surface electrocorticography recordings may falsely localize other cortical foci, leading to inaccurate diagnosis and treatment. The use of insular depth electrodes allows more precise localization of seizure foci. The authors describe the case of a young girl with seizures falsely localized to the cortex, with foci arising from the insula, as proven by depth electrode recordings. Resection of the insula yielded seizure control.
authors.affiliation: Department of Neurological Surgery, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, Washington 98105, USA.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Levitt
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Ojemann
authors.forename: John
authors.initials: J
authors.lastname: Kuratani
mesh_terms: D001931:Brain Mapping; D002540:Cerebral Cortex / Q000473:pathology* / Q000601:surgery; D002675:Child, Preschool; D003399:Craniotomy; D003937:Diagnosis, Differential; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods*; D017029:Epilepsy, Complex Partial / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging