Bioactive 2-arylbenzofuran derivatives from Morus wittiorum.
Investigation of an ethanol extract from the stem bark of Morus wittiorum led to the isolation of five new 2-arylbenzofuran derivatives that were named wittifuran S, wittifuran T, wittifuran V, wittifuran W and wittifuran X (1-5). Structures were determined on the basis of spectroscopic analysis. Two new wittifurans and five previously isolated compounds were assayed for antioxidant and anti-inflammatory activity.
Tan
Yong-Xia
YX
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yang
Yan
Y
Zhang
Ting
T
Chen
Ruo-Yun
RY
Yu
De-Quan
DQ
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005966:Glucuronidase / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018547:Plant Stems; D051381:Rats
D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D001572:Benzofurans; D010936:Plant Extracts; C557239:wittifuran; D005966:Glucuronidase