Iron toxicity: new conditions continue to emerge.
During the past half century, excessive/misplaced iron has been observed to be a risk factor for an increasing number and diversity of disease conditions. An extensive list of conditions and of the types of iron association were published in early 2008. Within the subsequent year, four additional disorders have been recognized to be enhanced by iron: aging muscle atrophy, viral replication, rosacea and pulmonary alveolar proteinosis. This paper adds new data and emphasis on these disorders as entities associated with increased iron load and toxicity.
Weinberg
Eugene D
ED
Department of Biology and Program in Medical Sciences, Indiana University, Bloomington, IN 47405, USA. eweinber@indiana.edu
D000818:Animals; D019190:Iron Overload / Q000150:complications*; D019266:Iron, Dietary / Q000633:toxicity*; D008297:Male; D009133:Muscular Atrophy / Q000209:etiology; D011649:Pulmonary Alveolar Proteinosis / Q000209:etiology; D051381:Rats; D012307:Risk Factors; D012393:Rosacea / Q000209:etiology; D014779:Virus Replication / Q000187:drug effects
D019266:Iron, Dietary