title: Studies directed toward the synthesis of the massileunicellins. 2.
abstract: The fully substituted hydroisobenzofuran core of the massileunicellins containing 8 contiguous stereocenters was prepared in 12 steps from (S)-(+)-carvone. Noteworthy elements of the synthesis include a one-step oxidative rearrangement/epoxidation, a novel stereoselective directed reduction of a keto diol, and a directed hydrogenation of a congested tetrasubstituted alkene.
authors.affiliation: Dept. of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
authors.forename: Yonghai
authors.initials: Y
authors.lastname: Chai
authors.forename: Zonghong
authors.initials: Z
authors.lastname: Mou
authors.forename: Matthias C
authors.initials: MC
authors.lastname: McIntosh