[Small cell lung cancer and anti-Hu syndrome].
BACKGROUND
The anti-Hu associated syndrome is a rare paraneoplastic neurological syndrome, which is principally associated with small-cell lung cancer.


METHODS
We report the case of a patient with the following clinical features: dysautonomia with severe gastroparesis, sensory neuropathy and a rhombencephalitis. Tumour regression was obtained with chemotherapy but the patient ultimately died from the neurological complications.


CONCLUSIONS
Neurological syndromes associated in small cell lung cancer with anti-Hu antibodies are very diverse. Cancer evolution is generally speaking more benign than usual with the prognosis linked to the severity of the neurological involvement.
Prim
N
N
Pôle de pathologie thoracique, service de pneumologie, hôpitaux universitaires de Strasbourg, BP 426, 67091 Strasbourg, France.
Mennecier
B
B
Behr
C
C
Fraisse
P
P
Echaniz-Laguna
A
A
Tranchant
C
C
Quoix
E
E
D000368:Aged; D000906:Antibodies / Q000276:immunology; D051959:ELAV Proteins / Q000276:immunology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000276:immunology; D008297:Male; D020364:Paraneoplastic Polyneuropathy / Q000175:diagnosis / Q000276:immunology; D055752:Small Cell Lung Carcinoma / Q000175:diagnosis / Q000276:immunology
D000906:Antibodies; D051959:ELAV Proteins