A novel and efficient method for the olefination of carbonyl compounds with  Grignard reagents in the presence of diethyl phosphite.
The widely available carbonyl compounds react with Grignard reagents in the presence of diethyl phosphite to give the corresponding olefins in good to excellent yields: A range of conjugated dienes, terminal olefins, multisubstituted-alkenes and conjugated enynes could be readily obtained by the method in mild conditions.
Wang
Tongqiang
T
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry. Chemical Engineering and Materials Science of Soochow University, Suzhou, 215123, People's Republic of China.
Hu
Yuanyuan
Y
Zhang
Songlin
S