Hypervirulent Clostridium difficile strains in hospitalized patients, Canada.
To determine the incidence rate of infections with North American pulsed-field types 7 and 8 (NAP7/NAP8) strains of Clostrodium difficile, ribotype 078, and toxinotype V strains, we examined data collected for the Canadian Nosocomial Infections Surveillance Program (CNISP) CDI surveillance project during 2004-2008. Incidence of human infections increased from 0.5% in 2004/2005 to 1.6% in 2008.
Mulvey
Michael R
MR
Public Health Agency of Canada, 1015 Arlington St, Winnipeg, Manitoba R3E 3R2, Canada. michael_mulvey@phac-aspc.gc.ca
Boyd
David A
DA
Gravel
Denise
D
Hutchinson
Jim
J
Kelly
Sharon
S
McGeer
Allison
A
Moore
Dorothy
D
Simor
Andrew
A
Suh
Kathryn N
KN
Taylor
Geoff
G
Weese
J Scott
JS
Miller
Mark
M
D000368:Aged; D002170:Canada / Q000453:epidemiology; D016360:Clostridioides difficile / Q000235:genetics / Q000472:pathogenicity*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D005798:Genes, Bacterial / Q000235:genetics; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011159:Population Surveillance; D021521:Ribotyping; D017422:Sequence Analysis, DNA