Effects of multiple doses of ambrisentan on the pharmacokinetics of a single dose of digoxin in healthy volunteers.
Richards
Duncan B
DB
Medicines Development Centre, GlaxoSmithKline, Harlow, UK. duncan.b.richards@gsk.com
Spence
Rebecca
R
Mandagere
Arun
A
Henderson
Linda S
LS
Magee
Mindy H
MH
D000293:Adolescent; D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000494:pharmacology*; D002316:Cardiotonic Agents / Q000493:pharmacokinetics*; D004077:Digoxin / Q000493:pharmacokinetics*; D004334:Drug Administration Schedule; D004347:Drug Interactions; D006801:Humans; D008297:Male; D008875:Middle Aged; D010666:Phenylpropionates / Q000008:administration & dosage / Q000494:pharmacology*; D011724:Pyridazines / Q000008:administration & dosage / Q000494:pharmacology*; D055815:Young Adult
D000959:Antihypertensive Agents; D002316:Cardiotonic Agents; D010666:Phenylpropionates; D011724:Pyridazines; D004077:Digoxin; C467894:ambrisentan