title: Total synthesis of (+/-)-galanthamine via a C3-selective Stille coupling and IMDA cycloaddition cascade of 3,5-dibromo-2-pyrone.
abstract: A new efficient synthetic route to (+/-)-galanthamine was devised by using a tandem C3-selective Stille coupling-IMDA cascade of 3,5-dibromo-2-pyrone as a key strategy.
authors.affiliation: Department of Chemistry, Hanyang University, Seoul 133-791, Korea.
authors.forename: Jay Hyok
authors.initials: JH
authors.lastname: Chang
authors.forename: Ho-Ung
authors.initials: HU
authors.lastname: Kang
authors.forename: In-Hak
authors.initials: IH
authors.lastname: Jung
authors.forename: Cheon-Gyu
authors.initials: CG
authors.lastname: Cho
mesh_terms: D003500:Cyclization; D005702:Galantamine / Q000138:chemical synthesis* / Q000737:chemistry; D011753:Pyrones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C450850:3,5-dibromo-2-pyrone; D011753:Pyrones; D005702:Galantamine