title: Acute retrobulbar optic neuritis and macular detachment associated with morning glory optic disc anomaly.
abstract: A 31-year-old woman with morning glory optic disc anomaly (MGDA) developed acute retrobulbar optic neuritis and a bullous macular detachment. MRI demonstrated truncation of the perineural space of the affected optic nerve as well as focal optic nerve enhancement. Optical coherence tomography (OCT) showed retinoschisis associated with the macular detachment. The MRI and OCT findings support the vitreous as the source of the subretinal fluid. This is the first reported case of optic neuritis in MGDA.
authors.affiliation: Department of Ophthalmology, APC 7, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. margiemurphy@cox.net
authors.forename: Marjorie A
authors.initials: MA
authors.lastname: Murphy
authors.forename: Robert H
authors.initials: RH
authors.lastname: Janigian
authors.forename: Theodoros
authors.initials: T
authors.lastname: Filippopoulos
authors.forename: Glenn A
authors.initials: GA
authors.lastname: Tung
mesh_terms: D000208:Acute Disease; D000328:Adult; D018450:Disease Progression; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D009898:Optic Disk / Q000002:abnormalities* / Q000503:physiopathology; D009900:Optic Nerve / Q000473:pathology / Q000503:physiopathology; D009901:Optic Nerve Diseases / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D009902:Optic Neuritis / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D010525:Peripheral Nerves / Q000473:pathology / Q000503:physiopathology; D012160:Retina / Q000473:pathology / Q000503:physiopathology; D012163:Retinal Detachment / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014822:Vitreous Body / Q000473:pathology / Q000503:physiopathology
chemical_list: D008775:Methylprednisolone