Multiple cranial neuropathy as the initial presentation of metastatic prostate adenocarcinoma: case report and review of literature.
The skull base is an atypical metastatic site for prostate carcinoma. It is usually encountered late in the disease process in patients with known advanced disease. However, skull base involvement causing cranial nerve palsies may rarely be the presenting sign of prostate carcinoma. Such patients may present to a number of specialties including neurosurgery and can pose a diagnostic challenge in the absence of lower urinary tract symptoms. Here, we describe an unusual case of prostate adenocarcinoma presenting as a central skull base tumour with multiple cranial neuropathy.
Kolias
Angelos G
AG
Department of Neurosurgery, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK. angeloskolias@gmail.com
Derham
Christopher
C
Mankad
Kshitij
K
Hasegawa
Harutomo
H
O'Kane
Roddy
R
Ismail
Azzam
A
Phillips
Nicholas I
NI
D000368:Aged; D003388:Cranial Fossa, Posterior / Q000473:pathology / Q000503:physiopathology; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis / Q000175:diagnosis / Q000473:pathology*; D019291:Skull Base / Q000473:pathology / Q000503:physiopathology; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000556:secondary*