title: Physical activity, quality of life, and the interest in physical exercise programs in patients undergoing palliative chemotherapy.
abstract: OBJECTIVE
  Quality of life is of major importance in patients with advanced cancers undergoing palliative chemotherapy. In contrast to the number of studies on physical activity in patients with curable malignancies, data on patients undergoing palliative chemotherapy are scarce.
  
  
  METHODS
  A total of 53 patients receiving palliative chemotherapy on an outpatient basis were interviewed using three standardized questionnaires within a time period of 4 weeks (Questionnaire for Measurement of Habitual Physical Activity, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C13 questionnaire, International Physical Activity questionnaire), and a questionnaire regarding patients' acceptance of a potential physical training program.
  
  
  RESULTS
  Thirty-six percent of the patients still performed self-instructed physical activities during palliative chemotherapy. Patients showed significantly higher values in the "leisure time index" during their malignancy than before (p < 0.01). Significantly positive correlations were found between "work index" and quality of life (p = 0.004), "work index" and physical function (p = 0.02), and "hours of physical activity per week" and quality of life (p < 0.05). A negative correlation was found between "work index" and fatigue (p < 0.05). Quality of life scores were significantly higher in patients with sportive activities ≥ 9 metabolic equivalent (MET) h/week than in patients with <9 MET h/weeks (p < 0.01). Sixty percent of patients indicated that they would be willing to participate in an individually adapted activity training program.
  
  
  CONCLUSIONS
  In patients undergoing palliative chemotherapy, a statistically significant positive correlation between physical activity and quality of life could be demonstrated. About two thirds of critically ill patients are interested in participating in training programs.
authors.affiliation: Department of Oncology/Hematology/Bone Marrow Transplantation/Pneumology, Hubertus-Wald-Tumorzentrum, University Cancer Center Hamburg, University Hospital Hamburg-Eppendorf, Martinistr 52, 20246 Hamburg, Germany. k.oechsle@uke.uni-hamburg.de
authors.forename: Karin
authors.initials: K
authors.lastname: Oechsle
authors.forename: Wiebke
authors.initials: W
authors.lastname: Jensen
authors.forename: Tobias
authors.initials: T
authors.lastname: Schmidt
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Reer
authors.forename: Klaus-Michael
authors.initials: KM
authors.lastname: Braumann
authors.forename: Maike
authors.initials: M
authors.lastname: de Wit
authors.forename: Carsten
authors.initials: C
authors.lastname: Bokemeyer
mesh_terms: D000328:Adult; D000368:Aged; D015444:Exercise / Q000523:psychology; D005081:Exercise Therapy / Q000379:methods* / Q000523:psychology; D005260:Female; D006801:Humans; D007899:Leisure Activities / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000523:psychology*; D010045:Outpatients; D010166:Palliative Care / Q000379:methods*; D010342:Patient Acceptance of Health Care; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014937:Work / Q000523:psychology