Multicomponent cascade transformation of D-glucal to furan-appended triazole glycoconjugates.
Novel one-pot three- and four-component transformations of D-glucal to furan-based hydroxy triazole glycoconjugates have been achieved by sequential addition of reagents in the presence of Cu(OTf)(2)-Cu powder as catalysts. In general the carbohydrate-derived products were formed with high diastereomeric purity.
Yousuf
Syed Khalid
SK
Bio-organic Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu, India-180001.
Taneja
Subhash Chandra
SC
Mukherjee
Debaraj
D
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D006001:Glycoconjugates / Q000138:chemical synthesis*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis*
D005663:Furans; D006001:Glycoconjugates; D008698:Mesylates; D014230:Triazoles; C001289:d-glucal; D003300:Copper; D003847:Deoxyglucose; C012077:trifluoromethanesulfonic acid; C039281:furan