title: Polyethylene terephthalate may yield endocrine disruptors.
abstract: BACKGROUND
  Recent reports suggest that endocrine disruptors may leach into the contents of bottles made from polyethylene terephthalate (PET). PET is the main ingredient in most clear plastic containers used for beverages and condiments worldwide and has previously been generally assumed not to be a source of endocrine disruptors.
  
  
  OBJECTIVE
  I begin by considering evidence that bottles made from PET may leach various phthalates that have been putatively identified as endocrine disruptors. I also consider evidence that leaching of antimony from PET containers may lead to endocrine-disrupting effects.
  
  
  CONCLUSIONS
  The contents of the PET bottle, and the temperature at which it is stored, both appear to influence the rate and magnitude of leaching. Endocrine disruptors other than phthalates, specifically antimony, may also contribute to the endocrine-disrupting effect of water from PET containers.
  
  
  CONCLUSIONS
  More research is needed in order to clarify the mechanisms whereby beverages and condiments in PET containers may be contaminated by endocrine-disrupting chemicals.
authors.affiliation: Montgomery Center for Research in Child and Adolescent Development, Exton, Pennsylvania 19341, USA. MCRCAD@verizon.net
authors.forename: Leonard
authors.initials: L
authors.lastname: Sax
mesh_terms: D000818:Animals; D000965:Antimony / Q000032:analysis / Q000737:chemistry / Q000633:toxicity; D001628:Beverages / Q000032:analysis; D001681:Biological Assay; D052244:Endocrine Disruptors / Q000032:analysis / Q000737:chemistry* / Q000633:toxicity; D018857:Food Packaging; D006801:Humans; D011093:Polyethylene Terephthalates / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity
chemical_list: D052244:Endocrine Disruptors; D011093:Polyethylene Terephthalates; D000965:Antimony