title: Down but not out: candidate gene-based studies still have value in a world dominated by whole genome approaches.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Sharma
authors.forename: Paul
authors.initials: P
authors.lastname: Bentley
mesh_terms: D000581:Amidohydrolases / Q000235:genetics* / Q000378:metabolism; D001120:Arginine / Q000031:analogs & derivatives / Q000097:blood; D044466:Asian People; D015415:Biomarkers / Q000097:blood; D002681:China; D003324:Coronary Artery Disease / Q000201:enzymology / Q000208:ethnology / Q000235:genetics*; D019317:Evidence-Based Medicine; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic; D012307:Risk Factors; D020521:Stroke / Q000201:enzymology / Q000208:ethnology / Q000235:genetics*; D013927:Thrombosis / Q000201:enzymology / Q000208:ethnology / Q000235:genetics*
chemical_list: D015415:Biomarkers; C018524:N,N-dimethylarginine; D001120:Arginine; D000581:Amidohydrolases; C059999:dimethylargininase