title: Design and an efficient synthesis of new thiorotenone derivatives.
abstract: A series of novel 4-aryl-thiopyrano[3,4-b]pyran-5-one derivatives were synthesized through an efficient one-pot three-component reaction under solvent-free conditions. This work provides a new series of derivatives of thiorotenone with potential biological activity for biomedical screening.
authors.affiliation: School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China.
authors.forename: Changsheng
authors.initials: C
authors.lastname: Yao
authors.forename: Cuihua
authors.initials: C
authors.lastname: Wang
authors.forename: Bei
authors.initials: B
authors.lastname: Jiang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Feng
authors.forename: Chenxia
authors.initials: C
authors.lastname: Yu
authors.forename: Tuanjie
authors.initials: T
authors.lastname: Li
authors.forename: Shujiang
authors.initials: S
authors.lastname: Tu
mesh_terms: D018360:Crystallography, X-Ray; D015195:Drug Design; D008968:Molecular Conformation; D012402:Rotenone / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D012402:Rotenone