Desulfitative cross-coupling of protecting group-free 2-thiouracil derivatives with organostannanes.
We here report a unique and efficient copper bromide mediated pallado-catalyzed coupling of protecting group-free 2-thiouracil derivatives with organostannanes. The nature of the copper appears to be crucial for successful cross coupling.
Sun
Qi
Q
School of Pharmaceutical Science, Peking University, 38, Xueyuan Road, Haidian District, Beijing, China, 100191.
Suzenet
Franck
F
Guillaumet
Gérald
G
D002384:Catalysis; D003300:Copper / Q000737:chemistry; D015394:Molecular Structure; D009947:Organotin Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism; D013889:Thiouracil / Q000737:chemistry*
D009947:Organotin Compounds; D013889:Thiouracil; D010165:Palladium; D003300:Copper