title: Conjugated polyelectrolyte capsules: light-activated antimicrobial micro "Roach Motels".
abstract: Microcapsules consisting of alternating layers of oppositely charged poly(phenylene ethynylene)-type conjugated polyelectrolytes (CPEs) were prepared via layer-by-layer deposition onto MnCO3 template particles followed by dissolution of the template particles using an ethylenediaminetetraacetate solution. The resulting microcapsules exhibit bright-green fluorescence emission characteristics of the CPEs. Strong antimicrobial activity was observed upon mixing of polyelectrolyte capsules with Cobetia marina or Pseudomonas aeruginosa followed by white-light irradiation. It was demonstrated that the materials act as highly effective light-activated micro "Roach Motels" with greater than 95% kill after exposure to approximately 1 h of white light.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Corbitt
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Sommer
authors.forename: Sireesha
authors.initials: S
authors.lastname: Chemburu
authors.forename: Katsu
authors.initials: K
authors.lastname: Ogawa
authors.forename: Linnea K
authors.initials: LK
authors.lastname: Ista
authors.forename: Gabriel P
authors.initials: GP
authors.lastname: Lopez
authors.forename: David G
authors.initials: DG
authors.lastname: Whitten
authors.forename: Kirk S
authors.initials: KS
authors.lastname: Schanze
mesh_terms: D000480:Alkynes / Q000737:chemistry; D004202:Disinfectants / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D004573:Electrolytes / Q000737:chemistry; D004987:Ethers / Q000737:chemistry; D018613:Microscopy, Confocal; D008856:Microscopy, Fluorescence; D055616:Microtechnology / Q000379:methods*; D044130:Oceanospirillaceae / Q000187:drug effects; D055668:Photochemical Processes; D011108:Polymers / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects
chemical_list: D000480:Alkynes; D004202:Disinfectants; D004573:Electrolytes; D004987:Ethers; D011108:Polymers; C436384:phenyleneethynylene