The contraceptive vaginal ring.
The contraceptive vaginal ring offers effective contraception that is self-administered, requires less frequent dosing than many other forms of contraception, and provides low doses of hormones. NuvaRing (Organon, Oss, The Netherlands), the only contraceptive vaginal ring approved for use in the United States, contains etonogestrel and ethinyl estradiol. It is inserted into the vagina for 3 weeks, followed by a 1-week ring-free period, and works by inhibiting ovulation. Most women note a beneficial effect on bleeding profiles and are satisfied with NuvaRing. Commonly reported adverse events include vaginitis, leukorrhea, headaches, and device-related events such as discomfort. Serious adverse events are rare. In Chile and Peru, progesterone-only vaginal contraceptive rings are available for nursing women. Studies are ongoing examining new formulations of vaginal contraceptive rings.
Edwardson
Jill
J
Department of Gynecology and Obstetrics, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Jamshidi
Roxanne
R
D003271:Contraceptive Agents, Female / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D003274:Contraceptive Devices, Female / Q000009:adverse effects / Q000639:trends; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D017135:Desogestrel / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D004338:Drug Combinations; D004347:Drug Interactions; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D004997:Ethinyl Estradiol / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D011372:Progestins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D012646:Self Administration / Q000379:methods
D003271:Contraceptive Agents, Female; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D004967:Estrogens; C516519:NuvaRing; D011372:Progestins; D004997:Ethinyl Estradiol; D017135:Desogestrel