Intraventricular amphotericin for absidiomycosis in an immunocompetent child.
Brain abscesses are uncommon in children. We report a 3-year-old, previously healthy and immunocompetent boy, with an Absidia brain abscess. He presented with decreased sensorium and status epilepticus. The brain abscess was detected using cranial computed tomography and magnetic resonance imaging, and the diagnosis was confirmed with pus and brain tissue cultures. The patient responded to surgical drainage with concomitant intravenous and intraventricular amphotericin B.
Tsung
L L Y
LL
Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. liliantsung@cuhk.edu.hk
Zhu
X L
XL
Chu
W C W
WC
Sun
D T F
DT
Cheung
K L
KL
Leung
T F
TF
D020095:Absidia / Q000302:isolation & purification; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D002675:Child, Preschool; D004322:Drainage / Q000379:methods; D006801:Humans; D007121:Immunocompetence; D007276:Injections, Intraventricular; D008297:Male; D009091:Mucormycosis / Q000188:drug therapy* / Q000382:microbiology
D000935:Antifungal Agents; D000666:Amphotericin B