False-positive IgM serology in coccidioidomycosis.
The clinical observation has been made that there might be an unacceptable number of false-positive enzyme immunoassay (EIA) test results for IgM among persons suspected of having coccidioidomycosis. Patients with a positive result for IgM by EIA are thought to have a diagnosis of acute coccidioidomycosis. However, this study found that 82% of patients with an IgM-positive and IgG-negative EIA result did not have coccidioidomycosis.
Kuberski
Tim
T
Infection Prevention Program/Quality Management, John C. Lincoln Health Network, 2423 West Dunlap Avenue, Suite 100, Phoenix, AZ 85021, USA. tjkubs@aol.com
Herrig
Judith
J
Pappagianis
D
D
D000908:Antibodies, Fungal / Q000097:blood*; D003045:Coccidioides / Q000276:immunology*; D003047:Coccidioidomycosis / Q000175:diagnosis*; D005189:False Positive Reactions; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D012699:Serology / Q000379:methods*
D000908:Antibodies, Fungal; D007074:Immunoglobulin G; D007075:Immunoglobulin M