title: Metabolic syndrome, aging, physical inactivity, and incidence of type 2 diabetes in general African population.
abstract: The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at least 94 cm for men and women. The second objective was to investigate the incidence and the determinants of type 2 diabetes in a prospective cohort of 807 non-diabetic Central Africans aged >or= 40 years from December 2004 to September 2008. During 3,156 person-years of median follow up, there were 93 type 2 diabetes cases (11.5%), corresponding to an incidence of 29 (95% CI 15-43) per 1,000 person-years. The independent predictors of incident type 2 diabetes were age >or= 45 years, physical inactivity, non-diabetic hyperglycaemia and metabolic syndrome regardless of criteria used. In conclusion, urgent prevention strategies are needed to curb the type 2 diabetes epidemic in Africa.
authors.affiliation: Department of Internal Medicine, University of Kinshasa, DRC. longombenza@yahoo.fr
authors.forename: B
authors.initials: B
authors.lastname: Longo-Mbenza
authors.forename: J B Kasiam Lasi
authors.initials: JB
authors.lastname: On'kin
authors.forename: A Nge
authors.initials: AN
authors.lastname: Okwe
authors.forename: N Kangola
authors.initials: NK
authors.lastname: Kabangu
authors.forename: S Mbungu
authors.initials: SM
authors.lastname: Fuele
mesh_terms: D000328:Adult; D000350:Africa, Central / Q000453:epidemiology; D017677:Age Distribution; D000375:Aging; D044383:Black People / Q000706:statistics & numerical data*; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology*; D008875:Middle Aged; D009043:Motor Activity; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors