Urinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury.
Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.
McMahon
Blaithin A
BA
University College Dublin, Catherine McAuley Centre, Dublin, Ireland.
Murray
Patrick Thomas
PT
D058186:Acute Kidney Injury / Q000378:metabolism*; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D042241:Early Diagnosis; D050556:Fatty Acid-Binding Proteins / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D015227:Lipid Peroxidation; D051379:Mice; D014551:Urinary Tract / Q000378:metabolism*
D015415:Biomarkers; D050556:Fatty Acid-Binding Proteins; D005230:Fatty Acids, Nonesterified; D005231:Fatty Acids, Unsaturated