title: New automated hepatitis C virus (HCV) core antigen assay as an alternative to real-time PCR for HCV RNA quantification.
abstract: An automated hepatitis C virus (HCV) antigen (Ag) assay was evaluated with clinical samples. Determination of HCV Ag and RNA levels in 282 subjects using Abbott HCV Ag and Roche Cobas TaqMan assays revealed that these two tests were highly correlated (r = 0.9464). Thus, the HCV Ag assay could be an alternative test to quantitative reverse transcription-PCR.
authors.affiliation: Department of Laboratory Medicine, Yonsei University College of Medicine, 250 Seongsan-no, Seodaemun-gu, Seoul 120-752, South Korea.
authors.forename: Yongjung
authors.initials: Y
authors.lastname: Park
authors.forename: Jong-Han
authors.initials: JH
authors.lastname: Lee
authors.forename: Beom Seok
authors.initials: BS
authors.lastname: Kim
authors.forename: Do Young
authors.initials: DY
authors.lastname: Kim
authors.forename: Kwang-Hyub
authors.initials: KH
authors.lastname: Han
authors.forename: Hyon-Suk
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000956:Antigens, Viral / Q000097:blood*; D001331:Automation / Q000379:methods*; D016174:Hepacivirus / Q000302:isolation & purification*; D006801:Humans; D012367:RNA, Viral / Q000097:blood; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013223:Statistics as Topic; D014758:Viral Core Proteins / Q000097:blood*; D019562:Viral Load / Q000379:methods*
chemical_list: D000956:Antigens, Viral; D012367:RNA, Viral; D014758:Viral Core Proteins; C069130:nucleocapsid protein, Hepatitis C virus