Variable transcription factor binding: a mechanism of evolutionary change.
This primer discusses a study from Bradley et al. in which changes in transcription factor binding between two Drosophila species are revealed by chromatin immunoprecipitation and high-throughput sequencing.
Wittkopp
Patricia J
PJ
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America. wittkopp@umich.edu
D000818:Animals; D001665:Binding Sites; D005075:Biological Evolution; D004247:DNA / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D016678:Genome; D011485:Protein Binding; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D014157:Transcription Factors; D004247:DNA