title: Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector-row computed tomography.
abstract: The aim of this study was to determine the accuracy of endoscopic ultrasonography (EUS) and multidetector-row computed tomography (MDCT) for the locoregional staging of gastric cancer. EUS and computed tomography (CT) are valuable tools for the preoperative evaluation of gastric cancer. With the introduction of new therapeutic options and the recent improvements in CT technology, further evaluation of the diagnostic accuracy of EUS and MDCT is needed.
  
  
  
  In total, 277 patients who underwent EUS and MDCT, followed by gastrectomy or endoscopic resection at Bundang Hospital, Seoul National University, from July 2006 to April 2008, were analyzed. The results from the preoperative EUS and MDCT were compared to the postoperative pathological findings.
  
  
  
  Among the 277 patients, the overall accuracy of EUS and MDCT for T staging was 74.7% and 76.9%, respectively. Among the 141 patients with visualized primary lesions on MDCT, the overall accuracy of EUS and MDCT for T staging was 61.7% and 63.8%, respectively. The overall accuracy for N staging was 66% and 62.8%, respectively. The performance of EUS and MDCT for large lesions and lesions at the cardia and angle had significantly lower accuracy than that of other groups. For EUS, the early gastric cancer lesions with ulcerative changes had significantly lower accuracy than those without ulcerative changes.
  
  
  
  For the preoperative assessment of individual T and N staging in patients with gastric cancer, the accuracy of MDCT was close to that of EUS. Both EUS and MDCT are useful complementary modalities for the locoregional staging of gastric cancer.
authors.affiliation: Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
authors.forename: Sung Wook
authors.initials: SW
authors.lastname: Hwang
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Lee
authors.forename: Sang Hyub
authors.initials: SH
authors.lastname: Lee
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Park
authors.forename: Jin Hyeok
authors.initials: JH
authors.lastname: Hwang
authors.forename: Jin Wook
authors.initials: JW
authors.lastname: Kim
authors.forename: Sook Hyang
authors.initials: SH
authors.lastname: Jung
authors.forename: Na Young
authors.initials: NY
authors.lastname: Kim
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Kim
authors.forename: Kyoung Ho
authors.initials: KH
authors.lastname: Lee
authors.forename: Hyung-Ho
authors.initials: HH
authors.lastname: Kim
authors.forename: Do Joong
authors.initials: DJ
authors.lastname: Park
authors.forename: Hye Seung
authors.initials: HS
authors.lastname: Lee
authors.forename: Hyun Chae
authors.initials: HC
authors.lastname: Jung
authors.forename: In Sung
authors.initials: IS
authors.lastname: Song
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging / Q000532:radiotherapy; D018279:Carcinoma, Signet Ring Cell / Q000000981:diagnostic imaging / Q000532:radiotherapy; D019160:Endosonography; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods