Both visual and fluorescent sensor for Zn2+ based on quinoline platform.
A fluorescent Zn(2+) sensor 2-(hydroxymethyl)-4-methyl-6-((quinolinyl-8-imino)methyl)phenol (HMQP) based on the 8-aminoquinoline platform has been synthesized. This sensor displays high selectivity, sensitive fluorescence enhancement, strong binding ability, and ratiometric response to Zn(2+) in Tris-HCl (50 mM, pH 7.54), THF-H(2)O (9:1, v/v). And an obvious color change between HMQP and Zn(2+)-MQP(-) can be visually observed by the naked eye. The composition of the complex Zn(2+)-MQP(-) has been found to be 1:2 based on the fluorescence/absorption titration and further confirmed by X-ray crystallography.
Zhou
Xiaoyan
X
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
Yu
Bingran
B
Guo
Yanling
Y
Tang
Xiaoliang
X
Zhang
Huihui
H
Liu
Weisheng
W
D000634:Aminoquinolines / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
D000634:Aminoquinolines; D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D015032:Zinc; C080436:8-aminoquinoline