Multiple cranial nerve enhancement in mitochondrial neurogastrointestinal encephalomyopathy.
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare disease that often presents with nonspecific white matter abnormalities on magnetic resonance imaging. Ptosis and ophthalmoparesis are a part of its clinical features. We report multiple cranial nerve contrast enhancement on magnetic resonance imaging in a patient with MNGIE and postulate that demyelination may be the responsible substrate for this previously unreported finding. This finding may also explain the cranial neuropathies that patients with MNGIE have.
Petcharunpaisan
Sasitorn
S
Department of Radiology, UNC Hospital, Chapel Hill, NC, USA. sasitorn@email.unc.edu
Castillo
Mauricio
M
D000328:Adult; D002100:Cachexia / Q000473:pathology; D003391:Cranial Nerves / Q000473:pathology*; D003937:Diagnosis, Differential; D005767:Gastrointestinal Diseases / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D017237:Mitochondrial Encephalomyopathies / Q000473:pathology*