title: Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of beta-(acylamino)acrylates: significant effect of substituents on 3,3'-positions of binaphthyl moiety.
abstract: A series of new chiral phosphine-phosphoramidite ligands with a 3,3'-substituted binaphthyl moiety were prepared from 1-phenylethylamine, and successfully applied in the Rh-catalyzed asymmetric hydrogenation of beta-(acylamino)-acrylates. The research disclosed that the substituents on the 3,3'-positions of binaphthyl moiety significantly influenced the enantioselectivity.
authors.affiliation: Institute of Pesticide, Hunan Agricultural University, Changsha 410128, China.
authors.forename: Xiao-Mao
authors.initials: XM
authors.lastname: Zhou
authors.forename: Jia-Di
authors.initials: JD
authors.lastname: Huang
authors.forename: Li-Bin
authors.initials: LB
authors.lastname: Luo
authors.forename: Chen-Lu
authors.initials: CL
authors.lastname: Zhang
authors.forename: Xiang-Ping
authors.initials: XP
authors.lastname: Hu
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D008024:Ligands; D009281:Naphthalenes / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010627:Phenethylamines / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000179:Acrylates; D008024:Ligands; D009281:Naphthalenes; D009943:Organophosphorus Compounds; D010627:Phenethylamines; D010720:Phosphines; C434331:phosphoramidite; C031721:naphthalene; D012238:Rhodium