Covalent attachment of polymersomes to surfaces.
We show that vesicles made of block copolymers with aldehyde end groups can be covalently attached to aminated and non-aminated, untreated glass surfaces. The attached vesicles were sufficiently stable to allow a detailed investigation of vesicle shapes by confocal laser scanning microscopy (CLSM) and AFM in aqueous solutions allowing reconstruction of 3D images of the vesicle structure. Covalently attached PCL-PEO, PLA-PEO, and PI-PEO block copolymer vesicles have different footprint areas and different shapes due to their differences in bilayer stiffness.
Domes
Stephanie
S
Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, D-20146 Hamburg, Germany.
Filiz
Volkan
V
Nitsche
Jasmin
J
Frömsdorf
Andreas
A
Förster
Stephan
S
D000586:Amination; D005898:Glass / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013499:Surface Properties
D011108:Polymers