title: Search for mechanisms of exceptional human longevity.
abstract: This study presents initial findings of a new ongoing research project aimed to identify important predictors and mechanisms of exceptional human longevity. For this purpose the detailed data on long-lived people surviving to 100 years in the Unites States are collected, validated, and analyzed. The study found that being born to a young mother is an important predictor of person's longevity. The study also found that the "stout" body build at age 30 years (being in the heaviest 15% of population) significantly decreases chances of survival to 100 years. These findings demonstrate that early-life and mid-life personal characteristics play an important role in human longevity.
authors.affiliation: Center on Aging, NORC and The University of Chicago, Chicago, Illinois 60637, USA. gavrilova@longevity-science.org
authors.forename: Natalia S
authors.initials: NS
authors.lastname: Gavrilova
authors.forename: Leonid A
authors.initials: LA
authors.lastname: Gavrilov
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D000818:Animals; D005260:Female; D006801:Humans; D008136:Longevity / Q000235:genetics / Q000502:physiology*; D008297:Male; D008423:Maternal Age; D016017:Odds Ratio; D012307:Risk Factors