[Effects of airborne fine particulate matters on human immunological indicators].
OBJECTIVE
To explore effects of airborne fine particulate matters on human immunological indicators.


METHODS
All subjects were measured the level of PM2. 5 individual exposure with personal sampling devices. Serum immunological indicators, such as WBC, NE, NE%, Ly, Ly%, CD4+, CD8+, CD4+ / CD8+, IgA, IgM, IgG and IgE were detected through enzyme-linked immunosorbent assay. Then, comparing the difference of PM2.5 exposure and immunological indicators between two groups.


RESULTS
For the level of PM2.5 daily exposure, traffic policemen (115.4 +/- 46.2) microg/m3) was significantly higher than residents ((74.9 +/- 40.1) +/- g/ m(-3)). And there was also significant difference in some immunological indicators, such as Ly%, CD4+, CD8+, IgM, IgG, IgE, CC 16 and CRP, between two groups.


CONCLUSIONS
Long-term high level of airborne fine particulate matters exposure may change some blood immunological indicators, affect the health of the immune system.
Gao
Zhiyi
Z
Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China. gao_zy2004@yahoo.com.cn
Li
Pengkun
P
Zhao
Jinzhuo
J
Jiang
Rongfang
R
Yang
Binjie
B
Zhang
Minhua
M
Song
Weimin
W
D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D002681:China; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects; D052638:Particulate Matter / Q000009:adverse effects* / Q000032:analysis; D016495:Police; D011795:Surveys and Questionnaires; D013997:Time Factors; D014598:Uteroglobin / Q000097:blood
D000393:Air Pollutants; D007136:Immunoglobulins; D052638:Particulate Matter; C556389:SCGB1A1 protein, human; D014598:Uteroglobin