title: [Nasal surgery in patients with systemic disorders].
abstract: Systemic disorders represent a heterogenous group of diseases which can primarily manifest at the nose and sinuses as limited disease or secondarily as part of the systemic involvement. Rhinologists therefore play an important role in the diagnostic but also therapeutic process. Although therapy of systemic disorders is primary systemic, additional nasal surgery may become necessary. Surgical procedures include sinus surgery for the treatment of complications of the orbit and the lacrimal duct, septorhinoplasty due to saddle nose deformity and closure of septal perforation. Since many systemic disorders represent very rare diseases, recommendations are based on the analysis of single case reports and studies with a limited number of patients. Even though data is still limited, experiences published so far have shown that autogenous cartilage or bone transplants can be used in nasal reconstruction of deformities caused by tuberculosis, leprosy, wegener's granulomatosis, sarcoidosis and relapsing polychondritis. Experiences gained from these diseases support our observation that well-established techniques of septorhinoplasty can be used in systemic disorders as well. However, reaching a state of remission is an essential condition before considering any rhinosurgery in these patients. Under these circumstances revision surgery has to be expected more frequently compared to the typical collective of patients undergoing septorhinoplasty. These observations in part may also be useful for the treatment of nasal septal perforations since implantation of cartilage- or bone grafts represents an essential step in the closure of septal perforations. Apart from the treatment of orbital complications, sinus surgery has been proven beneficial in reducing nasal symptoms and increasing quality of life in patients refractory to systemic treatment.
authors.affiliation: HNO Klinik und Poliklinik, Universitätsklinikum Münster, Münster. sachsef@mednet.uni-muenster.de
authors.forename: F
authors.initials: F
authors.lastname: Sachse
authors.forename: W
authors.initials: W
authors.lastname: Stoll
mesh_terms: D003937:Diagnosis, Differential; D004724:Endoscopy; D006801:Humans; D009300:Nasal Septum / Q000601:surgery; D009667:Nose Deformities, Acquired / Q000209:etiology / Q000601:surgery; D009668:Nose Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D010254:Paranasal Sinus Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D010348:Patient Care Team; D011379:Prognosis; D011788:Quality of Life; D012225:Rhinoplasty / Q000379:methods*