Gold-catalyzed Intermolecular [4C + 3C] Cycloaddition Reactions.
In the presence of the N-heterocyclic carbene gold catalyst (NHC-AuIPr, 7), propargyl esters 1a-f and 13 undergo a [4C + 3C] cycloaddition reaction with cyclopentadiene and furan under mild conditions. The evidence suggests the formation of the seven-membered ring occurs by a direct cycloaddition process, rather than a stepwise cyclopropanation/Cope rearrangement sequence.
Gung
Benjamin W
BW
Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056.
Bailey
Lauren N
LN
Wonser
Josh
J