title: Highly diastereoselective preparation of homoallylic alcohols containing two contiguous quaternary stereocenters in acyclic systems from simple terminal alkynes.
abstract: The combined carbocupration of terminal alkynes followed by a zinc homologation and further reaction with ketones lead, in a single-pot operation, to the creation of homoallylic alcohols possessing two consecutive quaternary stereocenters with excellent diastereoselectivity.
authors.affiliation: The Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry and the Lise Meitner-Minerva Center for Computational Quantum Chemistry, Technion-Israel Institute of Technology, Technion City, Haifa 32000, Israel.
authors.forename: Bishnu
authors.initials: B
authors.lastname: Dutta
authors.forename: Noga
authors.initials: N
authors.lastname: Gilboa
authors.forename: Ilan
authors.initials: I
authors.lastname: Marek