title: Protective role of complement C5a in an experimental model of Staphylococcus aureus bacteremia.
abstract: The complement system is a key component of the innate immune response. Here, we have examined the role of complement anaphylatoxin C5a in an experimental model of Staphylococcus aureus bacteremia. Our data provide compelling evidence for a protective role of C5a during staphylococcal bloodstream infection.
authors.affiliation: Infection Immunology Research Group, Helmholtz Center for Infection Research, Braunschweig, Germany.
authors.forename: Maren
authors.initials: M
authors.lastname: von Köckritz-Blickwede
authors.forename: Stephanie
authors.initials: S
authors.lastname: Konrad
authors.forename: Simon
authors.initials: S
authors.lastname: Foster
authors.forename: J Engelbert
authors.initials: JE
authors.lastname: Gessner
authors.forename: Eva
authors.initials: E
authors.lastname: Medina
mesh_terms: D000818:Animals; D016470:Bacteremia / Q000276:immunology*; D015936:Complement C5a / Q000235:genetics / Q000276:immunology*; D005260:Female; D007113:Immunity, Innate / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D013203:Staphylococcal Infections / Q000276:immunology*
chemical_list: D015936:Complement C5a