Development of a self-etching primer with higher shelf life and greater dentin bond stability.
To examine the effects from the chemical structure of acidic methacrylate monomers on the primer's shelf life, N-methacryloyl-2aminoethylphosphonic acid (NMEP)- N-methacryloyl glycine (NMGly), 2-methacryloyloxyethyl dihydrogen phosphate (MEP)-NMGly and 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-NMGly primers were designed. Immediately after preparation, these primers were stored at 40 degrees C for 0, 6 and 14 weeks. At the end of each storage period, (13)C NMR observations were performed. Shear bond strengths of resin to dentin, conditioned by non-stored or stored primers, were measured. Alteration rates of these primers were strongly dependent on the chemical structure of acidic methacrylate monomers. The NMEP-NMGly primer exhibited noticeably higher hydrolytic stability and greater bond strength stability than MEP-NMGly and MDP-NMGly primers. These results demonstrated that methacryl amide monomers, NMEP and NMGly, are more advantageous than methacryl ester monomers. To develop self-etching primers with longer shelf life, it is essential to utilize acidic and hydrophilic methacryl amide monomers.
Ma
Shen
S
Department of Dental Biomaterials, Nihon University Graduate School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan. nishiyama.norihiro@nihon-u.ac.jp
D000134:Acid Etching, Dental; D000178:Acrylamides / Q000737:chemistry*; D001840:Dental Bonding; D003799:Dental Stress Analysis; D017220:Dentin-Bonding Agents / Q000737:chemistry; D004355:Drug Stability; D005998:Glycine / Q000031:analogs & derivatives / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry*; D019279:Resin Cements / Q000737:chemistry*; D033081:Shear Strength
D000178:Acrylamides; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D019279:Resin Cements; C093041:N-methacryloyl glycine; C069749:methacryloyloxydecyl dihydrogen phosphate; C045985:methacrylamide; D005998:Glycine