title: Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity.
abstract: Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged articular joints. However, recent investigations have revealed the active anti-inflammatory or chondroprotective effect of HA, suggesting its potential role in attenuation of joint damage. In particular, interactions between HA and other inflammatory mediators are attracting interest. This review summarizes several aspects of recent investigations of the anti-inflammatory effects of HA in arthritis.
authors.affiliation: Department of Biochemistry.
authors.forename: Kayo
authors.initials: K
authors.lastname: Masuko
authors.forename: Minako
authors.initials: M
authors.lastname: Murata
authors.forename: Kazuo
authors.initials: K
authors.lastname: Yudoh
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kato
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakamura