title: Simplifying adherence in schizophrenia.
abstract: Treatment nonadherence is a formidable challenge in today's clinical practice. Despite decades of focused research, medication adherence continues to be a significant risk factor for poor prognosis in schizophrenia. Studies demonstrate that no single strategy is effective for all patients and that a multidisciplinary approach customized to the patient's individual needs results in improved adherence rates. This Open Forum presents a comprehensive model for organizing and incorporating current and future evidence-based strategies with a focus on educational strategies, psychotherapeutic techniques, and a strong therapeutic alliance.
authors.affiliation: Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, 3555 Harden St., Suite 301, Columbia, SC 29203, USA. shardeman@uscmed.sc.edu
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Hardeman
authors.forename: Richard K
authors.initials: RK
authors.lastname: Harding
authors.forename: Meera
authors.initials: M
authors.lastname: Narasimhan
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001364:Awareness; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D019317:Evidence-Based Medicine; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007600:Judgment; D008134:Long-Term Care; D055118:Medication Adherence / Q000523:psychology*; D010353:Patient Education as Topic; D010817:Physician-Patient Relations; D011368:Professional-Family Relations; D011613:Psychotherapy; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations