[GBV-C infection in HIV-infected patients in the Russian Federation].
The spread and genotypical variability of GBV-C virus were determined among the HIV-positive patients in the Russian Federation. More than a fourth (26.2%) of the HIV-infected patients were shown to have GBV-C coinfection; all virus isolates belonged to genotype 2 with a predominance of subtype 2a. Analysis of the impact of GBV-C coinfection on HIV burden and CD4 lymphocyte levels showed no significant impact on these basic characteristics of HIV infection. However, coinfection with GBV-C and HIV was associated with the higher frequency of undetectably low ( < 400 copies/ml) of HIV burden, which enables GBV-C infection to be regarded as a potentially favorable factor in HIV infection.
Dmitriev
P N
PN
Tsikina
M N
MN
Moiseeva
A V
AV
Serkov
I L
IL
Pronin
A Iu
AIu
Popova
O E
OE
Isaeva
O V
OV
Kiuregian
K K
KK
Mikhaĭlov
M I
MI
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000821:virology; D000293:Adolescent; D000328:Adult; D018791:CD4 Lymphocyte Count; D015897:Comorbidity; D018178:Flaviviridae Infections / Q000453:epidemiology* / Q000821:virology; D029407:GB virus C / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D014644:Genetic Variation; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008875:Middle Aged; D012367:RNA, Viral / Q000235:genetics; D012426:Russia / Q000453:epidemiology; D019562:Viral Load
D012367:RNA, Viral