title: Release of TEGDMA from composite during the chewing situation.
abstract: The aim of this study was to investigate the triethylene glycol (TEGDMA) elution kinetics from light-cured composite with and without chewing simulation over a time period of 86 h. An experimental composite with TEGDMA labeled with a tracer dose of 14C-TEGDMA was used. The material parameters were in the range of commercially available composites. The mastification was simulated with the Fatigue-machine and the MUC-3 chewing simulator. 14C was eluted to 2.55% of the applied 14C-TEGDMA dose within 86 h after chewing simulation with the Fatigue-machine and to 2.60% after chewing simulation with the MUC-3. Similar 14C-kinetic data were found for 14C-elution with and without chewing simulation with the Fatigue-machine and with MUC-3. During the first 26 h after the beginning of the experiments a linear 14C-elution kinetic was observed, followed by a second linear 14C-elution kinetic with a lower slope up to 86 h in both apparatus. It could be shown that chewing simulation has no significant (p<0.05) effect on the release of 14C-TEGDMA (and/or 14C-degradation products) from polymerized composites.
authors.affiliation: Institute of Clinical Chemistry, Campus Grosshadern, Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377 Munich, Germany. juergen.durner@med.uni-muenchen.de
authors.forename: J
authors.initials: J
authors.lastname: Durner
authors.forename: B
authors.initials: B
authors.lastname: Glasl
authors.forename: J
authors.initials: J
authors.lastname: Zaspel
authors.forename: K H
authors.initials: KH
authors.lastname: Kunzelmann
authors.forename: R
authors.initials: R
authors.lastname: Hickel
authors.forename: F X
authors.initials: FX
authors.lastname: Reichl
mesh_terms: D002250:Carbon Radioisotopes / Q000032:analysis; D003188:Composite Resins / Q000737:chemistry*; D003799:Dental Stress Analysis / Q000295:instrumentation; D006801:Humans; D007700:Kinetics; D055115:Light-Curing of Dental Adhesives; D008409:Mastication; D008422:Materials Testing; D011092:Polyethylene Glycols / Q000032:analysis*; D011109:Polymethacrylic Acids / Q000032:analysis*
chemical_list: D002250:Carbon Radioisotopes; D003188:Composite Resins; D011109:Polymethacrylic Acids; C020946:triethylene glycol dimethacrylate; D011092:Polyethylene Glycols