title: Endemic goitre and excessive iodine in urine and drinking water among Saharawi refugee children.
abstract: OBJECTIVE
  To assess the prevalence of enlarged thyroid volume (Tvol) in Saharawi refugee children, and their urinary iodine concentration (UIC), and to identify possible sources of excess iodine intake.
  
  
  METHODS
  A cross-sectional survey was performed during January-February 2007. Tvol was measured by ultrasound and iodine concentration was analysed in casual urine samples, in household drinking water and in milk samples from household livestock.
  
  
  METHODS
  The study was undertaken in four refugee camps in the Algerian desert.
  
  
  METHODS
  The subjects were 421 Saharawi children, 6-14 years old.
  
  
  RESULTS
  Enlarged Tvol was found in 56 % (Tvol-for-age) and 86 % (Tvol-for-body-surface-area) of the children. The median (25th percentile-75th percentile, P25-P75) UIC was 565 (357-887) microg/l. The median (P25-P75) iodine concentration in household drinking water was 108 (77-297) microg/l. None of the children had UIC below 100 microg/l, 16 % had UIC between 100 and 299 microg/l, and 84 % had UIC above 300 microg/l. There was a positive association between Tvol and whether the household possessed livestock.
  
  
  CONCLUSIONS
  The children are suffering from endemic goitre and high UIC caused probably by an excessive intake of iodine. The excessive iodine intakes probably originate from drinking water and milk.
authors.affiliation: Akershus University College, Lillestrøm, Norway. sigrun.henjum@hiak.no
authors.forename: Sigrun
authors.initials: S
authors.lastname: Henjum
authors.forename: Ingrid
authors.initials: I
authors.lastname: Barikmo
authors.forename: Anne Karine
authors.initials: AK
authors.lastname: Gjerlaug
authors.forename: Abderraháman
authors.initials: A
authors.lastname: Mohamed-Lehabib
authors.forename: Arne
authors.initials: A
authors.lastname: Oshaug
authors.forename: Tor Arne
authors.initials: TA
authors.lastname: Strand
authors.forename: Liv Elin
authors.initials: LE
authors.lastname: Torheim
mesh_terms: D000293:Adolescent; D000462:Algeria / Q000453:epidemiology; D000818:Animals; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006043:Goiter, Endemic / Q000453:epidemiology*; D006801:Humans; D007455:Iodine / Q000008:administration & dosage* / Q000009:adverse effects / Q000652:urine*; D008297:Male; D008892:Milk / Q000737:chemistry*; D015995:Prevalence; D012036:Refugees; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water; D007455:Iodine