Levofloxacin-induced Achilles tendinitis in a young adult in the absence of predisposing conditions.
Fluoroquinolones (FQs) represent a major class of antimicrobials that have a high potential as therapeutic agents. Although FQs are generally safe for the use as antimicrobials, they may induce tendinopathic complications such as tendinitis and tendon rupture. A number of factors have been suggested to further predispose a patient to such injuries. Hitherto, a few published cases on tendon disorders have implicated levofloxacin, a more recently introduced FQ. Here, we report a patient with levofloxacin-induced Achilles tendinitis, who exhibited no known predisposing factors. A 20-year-old man without any history of disease or medication presented with community-acquired pneumonia. Levofloxacin was administered and 3 days later, he complained of pain in the left Achilles tendon and revealed redness and swelling in the area. On suspecting Achilles tendinitis, levofloxacin treatment was discontinued, and the tendinitis subsequently improved. To our knowledge, this is the first case report on FQ-induced Achilles tendinitis in Korea.
Durey
Areum
A
Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
Baek
Yong Soo
YS
Park
Jin Seok
JS
Lee
Kwangsoo
K
Ryu
Jeong-Seon
JS
Lee
Jin-Soo
JS
Cheong
Moon-Hyun
MH
D000125:Achilles Tendon / Q000187:drug effects* / Q000473:pathology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000188:drug therapy; D004198:Disease Susceptibility; D006801:Humans; D064704:Levofloxacin; D008297:Male; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D011014:Pneumonia / Q000188:drug therapy; D052256:Tendinopathy / Q000139:chemically induced*; D055815:Young Adult
D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin