title: Familial occipital and nervus intermedius neuralgia in a Swiss family.
abstract: Familial trigeminal neuralgia has been reported in 1-2% of cases consistent with an autosomal dominant inheritance. We present a Swiss family with several members suffering from occipital and nervus intermedius neuralgia alone or in combination. We suggest that peripheral sensory anastomoses or central convergence of afferent pathways could explain neuralgia affecting two cranial nerves. The pedigree has two main characteristics: (1) affected individuals in two generations and (2) in the first generation the father is affected, in the second generation all women are affected, and none of the men. This is suggestive of an X-linked dominant or an autosomal dominant mode of inheritance.
authors.affiliation: Department of Neurology, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Franz
authors.initials: F
authors.lastname: Riederer
authors.forename: Peter S
authors.initials: PS
authors.lastname: Sándor
authors.forename: Michael
authors.initials: M
authors.lastname: Linnebank
authors.forename: Dominik A
authors.initials: DA
authors.lastname: Ettlin
mesh_terms: D005154:Facial Nerve / Q000503:physiopathology; D005156:Facial Neuralgia / Q000175:diagnosis* / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006261:Headache / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D040582:Inheritance Patterns / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013127:Spinal Nerves / Q000503:physiopathology; D013557:Switzerland