title: Hospital-acquired pneumonia and bacteremia caused by Legionella pneumophila in an immunocompromised patient.
abstract: The Legionella species is an important cause of communityand hospital-acquired pneumonia. Bacteremic pneumonia caused by L. pneumophila is rarely reported. We describe the first reported case of hospital-acquired pneumonia and bacteremia caused by L. pneumophila from Taiwan in a patient with idiopathic thrombocytopenic purpura who received steroid treatment. The patient was successfully treated with ceftazidime and clindamycin initially, followed by ciprofloxacin for 14 days. The blood isolate was further confirmed by 16S rDNA sequence analysis.
authors.affiliation: Dept. of Internal Medicine, Cardinal-Tien Hospital, Taipei, Taiwan.
authors.forename: C-C
authors.initials: CC
authors.lastname: Lai
authors.forename: C-K
authors.initials: CK
authors.lastname: Tan
authors.forename: C-H
authors.initials: CH
authors.lastname: Chou
authors.forename: H-L
authors.initials: HL
authors.lastname: Hsu
authors.forename: Y-T
authors.initials: YT
authors.lastname: Huang
authors.forename: C-H
authors.initials: CH
authors.lastname: Liao
authors.forename: P-R
authors.initials: PR
authors.lastname: Hsueh
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D002442:Ceftazidime / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006761:Hospitals; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D016952:Legionella pneumophila / Q000235:genetics / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000188:drug therapy; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013256:Steroids / Q000009:adverse effects / Q000627:therapeutic use; D013624:Taiwan
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D013256:Steroids; D002981:Clindamycin; D002939:Ciprofloxacin; D002442:Ceftazidime