title: Interventional MRI using multiple 3D angiography roadmaps with real-time imaging.
abstract: OBJECTIVE
  To enhance real-time magnetic resonance (MR)-guided catheter navigation by overlaying colorized multiphase MR angiography (MRA) and cholangiopancreatography (MRCP) roadmaps in an anatomic context.
  
  
  METHODS
  Time-resolved MRA and respiratory-gated MRCP were acquired prior to real-time imaging in a pig model. MRA and MRCP data were loaded into a custom real-time MRI reconstruction and visualization workstation where they were displayed as maximum intensity projections (MIPs) in distinct colors. The MIPs were rendered in 3D together with real-time multislice imaging data using alpha blending. Interactive rotation allowed different views of the combined data.
  
  
  RESULTS
  Fused display of the previously acquired MIP angiography data with real-time imaging added anatomical context during endovascular interventions in swine. The use of multiple MIPs rendered in different colors facilitated differentiation of vascular structures, improving visual feedback during device navigation.
  
  
  CONCLUSIONS
  Interventional real-time MRI may be enhanced by combining with previously acquired multiphase angiograms. Rendered as 3D MIPs together with 2D slice data, this technique provided useful anatomical context that enhanced MRI-guided interventional applications.
authors.affiliation: Translational Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1061, USA. saybasilih@nhlbi.nih.gov
authors.forename: Haris
authors.initials: H
authors.lastname: Saybasili
authors.forename: Anthony Z
authors.initials: AZ
authors.lastname: Faranesh
authors.forename: Christina E
authors.initials: CE
authors.lastname: Saikus
authors.forename: Cengizhan
authors.initials: C
authors.lastname: Ozturk
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Lederman
authors.forename: Michael A
authors.initials: MA
authors.lastname: Guttman
mesh_terms: D000818:Animals; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008168:Lung / Q000473:pathology; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D008953:Models, Anatomic; D013552:Swine; D017131:Thrombectomy / Q000379:methods; D013997:Time Factors