Complete remission of coronary vasculitis in Churg-Strauss Syndrome by prednisone and cyclophosphamide.
The heart is involved in up to 50% of all patients with Churg-Strauss syndrome, but vasculitis of the coronary arteries has only been rarely documented. We present a young patient with severe coronary aneurysms and stenotic lesions due to a Churg-Strauss vasculitis. Prompt therapy with prednisone and cyclophosphamide resulted in the complete resolution of all lesions.
Riksen
Niels P
NP
Department of Internal Medicine, Division of Vascular Medicine, Radboud University Nijmegen Medical Center, Geert Grooteplein 21, PO Box 9101, 6500 HB Nijmegen, The Netherlands. N.Riksen@aig.umcn.nl
Gehlmann
Helmut
H
Brouwer
Annemarie E
AE
van Deuren
Marcel
M
D000293:Adolescent; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D003327:Coronary Disease / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D003331:Coronary Vessels / Q000187:drug effects / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D012074:Remission Induction; D016896:Treatment Outcome; D014657:Vasculitis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011239:Prednisolone