[A case of non-occulsive mesentery ischemia with pulmonary embolism due to protein C deficiency].
Protein C is an important physiological anticoagulant factor. Protein C deficiency has been linked to venous thrombosis at unusual sites, including the cerebral and mesenteric veins. Hereditary protein C deficiency is inherited primarily as an autosomal dominant trait with incomplete penetrance. Protein C and S deficiencies are known to increase the risk of venous thrombosis and pulmonary thromboembolism. Testing for protein C levels and function is necessary for the detection of both type I and type II protein C deficiency. In this article, we report a case of pulmonary embolism and mesentery ischemia due to type 1 protein C deficiency.
Kim
Tae Wan
TW
Department of Internal Medicine, Kangbuk Samsung Hospital, Jongno-gu, Seoul, Korea.
Choi
Sung Youn
SY
Kang
Im Ju
IJ
Kang
Yoon Jung
YJ
Shin
Dong Hyuk
DH
D003113:Colonoscopy; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000209:etiology; D018810:Magnetic Resonance Angiography; D008297:Male; D008642:Mesenteric Veins; D008875:Middle Aged; D020151:Protein C Deficiency / Q000150:complications* / Q000235:genetics; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed