title: Warfarin: to use or not to use in chronic kidney disease patients?
abstract: Is the risk of major bleeding the only reason to be concerned about oral anticoagulant therapy in chronic kidney disease patients? We consider another potential adverse effect of long-term Coumadin use in chronic kidney disease patients as comparably devastating: the threat of inducing creeping vascular calcification.
authors.affiliation: Division of Nephrology, University of Milan, S. Paolo Hospital, Via A. di Rudini 8, Milan, Italy. mariocozzolino@hotmail.com
authors.forename: Mario
authors.initials: M
authors.lastname: Cozzolino
authors.forename: Vincent
authors.initials: V
authors.lastname: Brandenburg
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D002135:Calcium-Binding Proteins / Q000502:physiology; D002908:Chronic Disease; D016326:Extracellular Matrix Proteins / Q000502:physiology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000150:complications; D006435:Renal Dialysis; D014859:Warfarin / Q000009:adverse effects*; D000097568:Matrix Gla Protein
chemical_list: D000925:Anticoagulants; D002135:Calcium-Binding Proteins; D016326:Extracellular Matrix Proteins; D014859:Warfarin; D000097568:Matrix Gla Protein