title: [GBV-C infection in HIV-infected patients in the Russian Federation].
abstract: The spread and genotypical variability of GBV-C virus were determined among the HIV-positive patients in the Russian Federation. More than a fourth (26.2%) of the HIV-infected patients were shown to have GBV-C coinfection; all virus isolates belonged to genotype 2 with a predominance of subtype 2a. Analysis of the impact of GBV-C coinfection on HIV burden and CD4 lymphocyte levels showed no significant impact on these basic characteristics of HIV infection. However, coinfection with GBV-C and HIV was associated with the higher frequency of undetectably low ( < 400 copies/ml) of HIV burden, which enables GBV-C infection to be regarded as a potentially favorable factor in HIV infection.
authors.forename: P N
authors.initials: PN
authors.lastname: Dmitriev
authors.forename: M N
authors.initials: MN
authors.lastname: Tsikina
authors.forename: A V
authors.initials: AV
authors.lastname: Moiseeva
authors.forename: I L
authors.initials: IL
authors.lastname: Serkov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Pronin
authors.forename: O E
authors.initials: OE
authors.lastname: Popova
authors.forename: O V
authors.initials: OV
authors.lastname: Isaeva
authors.forename: K K
authors.initials: KK
authors.lastname: Kiuregian
authors.forename: M I
authors.initials: MI
authors.lastname: Mikhaĭlov
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000821:virology; D000293:Adolescent; D000328:Adult; D018791:CD4 Lymphocyte Count; D015897:Comorbidity; D018178:Flaviviridae Infections / Q000453:epidemiology* / Q000821:virology; D029407:GB virus C / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D014644:Genetic Variation; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008875:Middle Aged; D012367:RNA, Viral / Q000235:genetics; D012426:Russia / Q000453:epidemiology; D019562:Viral Load
chemical_list: D012367:RNA, Viral