title: Brønsted acid-catalyzed cascade cycloisomerization of enynes via acetylene cations and sp3-hybridized C-H bond activation.
abstract: A novel Brønsted acid-catalyzed cascade cycloisomerization of cyclic and acyclic enynes via acetylene cation cyclization followed by cleavage of the entirely inactive C(sp(3))-H bond is described. The reaction proceeds efficiently under mild conditions to afford various tri- and bicyclic compounds in good to high yields.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan. tjin@mail.tains.tohoku.ac.jp
authors.forename: Tienan
authors.initials: T
authors.lastname: Jin
authors.forename: Masafumi
authors.initials: M
authors.lastname: Himuro
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto