Adiponectin levels and its association with hyperglycaemia in adult Filipino participants in the 2003--04 National Nutrition and Health Survey.
Our objective was to determine the association of serum adiponectin levels with the presence of IFG or DM in Filipinos. This case control study used sera of adult participants in the Philippines' NNHeS: 2003-04. Subjects were divided into: normoglycaemic control, impaired fasting glucose, and type 2 diabetes mellitus. Seventy-seven prediabetic and 83 diabetic subjects were included in the prediabetic and diabetic groups, respectively. There was no significant difference in adiponectin values between control and prediabetic subjects. Diabetic subjects had significantly lower mean serum adiponectin levels (10.7 versus 14.2 microg/ml, p=0.0198) compared with age- and BMI-matched control subjects. Diabetic subjects were found most frequently (43.53%) in the lowest tertile (1.6-7.2 microg/ml) and least frequently (20%) in the highest tertile (14-84 microg/ml) of adiponectin values. We conclude that Filipinos with diabetes mellitus had significantly lower adiponectin levels compared with normoglycaemic subjects.
Paz-Pacheco
Elizabeth
E
Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of the Philippines--Philippine General Hospital, Manila, Philippines.
Lim-Abrahan
Mary Anne
MA
Sy
Rosa Allyn G
RA
Jasul
Gabriel V
GV
Sison
Cherrie Mae C
CM
Laurel
Aurora F
AF
D052242:Adiponectin / Q000097:blood; D000328:Adult; D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data*; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000208:ethnology / Q000503:physiopathology; D015536:Down-Regulation; D005215:Fasting / Q000097:blood; D005260:Female; D006306:Health Surveys; D006801:Humans; D006943:Hyperglycemia / Q000097:blood* / Q000208:ethnology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010679:Philippines / Q000453:epidemiology; D011236:Prediabetic State / Q000097:blood* / Q000208:ethnology / Q000503:physiopathology; D013997:Time Factors
C499918:ADIPOQ protein, human; D052242:Adiponectin; D015415:Biomarkers; D001786:Blood Glucose