title: Levofloxacin-induced Achilles tendinitis in a young adult in the absence of predisposing conditions.
abstract: Fluoroquinolones (FQs) represent a major class of antimicrobials that have a high potential as therapeutic agents. Although FQs are generally safe for the use as antimicrobials, they may induce tendinopathic complications such as tendinitis and tendon rupture. A number of factors have been suggested to further predispose a patient to such injuries. Hitherto, a few published cases on tendon disorders have implicated levofloxacin, a more recently introduced FQ. Here, we report a patient with levofloxacin-induced Achilles tendinitis, who exhibited no known predisposing factors. A 20-year-old man without any history of disease or medication presented with community-acquired pneumonia. Levofloxacin was administered and 3 days later, he complained of pain in the left Achilles tendon and revealed redness and swelling in the area. On suspecting Achilles tendinitis, levofloxacin treatment was discontinued, and the tendinitis subsequently improved. To our knowledge, this is the first case report on FQ-induced Achilles tendinitis in Korea.
authors.affiliation: Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
authors.forename: Areum
authors.initials: A
authors.lastname: Durey
authors.forename: Yong Soo
authors.initials: YS
authors.lastname: Baek
authors.forename: Jin Seok
authors.initials: JS
authors.lastname: Park
authors.forename: Kwangsoo
authors.initials: K
authors.lastname: Lee
authors.forename: Jeong-Seon
authors.initials: JS
authors.lastname: Ryu
authors.forename: Jin-Soo
authors.initials: JS
authors.lastname: Lee
authors.forename: Moon-Hyun
authors.initials: MH
authors.lastname: Cheong
mesh_terms: D000125:Achilles Tendon / Q000187:drug effects* / Q000473:pathology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000188:drug therapy; D004198:Disease Susceptibility; D006801:Humans; D064704:Levofloxacin; D008297:Male; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D011014:Pneumonia / Q000188:drug therapy; D052256:Tendinopathy / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin