title: Palladium-catalyzed cyclocarbonylation of arynes with methyl allyl carbonates: selective synthesis of 1H-inden-1-ones.
abstract: A selective protocol for the synthesis of 2-methylene-3-substituted-2,3-dihydro-1H-inden-1-ones and 2-benzylidene-2,3-dihydro-1H-inden-1-ones has been developed via palladium-catalyzed cyclocarbonylation reactions of arynes with allyl carbonates and carbon monooxide (CO). It is noteworthy that the selectivity of this new route is depended on both substrates and ligands.
authors.affiliation: Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha 410081, China.
authors.forename: Shao-Feng
authors.initials: SF
authors.lastname: Pi
authors.forename: Xu-Heng
authors.initials: XH
authors.lastname: Yang
authors.forename: Xiao-Cheng
authors.initials: XC
authors.lastname: Huang
authors.forename: Yun
authors.initials: Y
authors.lastname: Liang
authors.forename: Guan-Nan
authors.initials: GN
authors.lastname: Yang
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Zhang
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000498:Allyl Compounds / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000498:Allyl Compounds; D002254:Carbonates; D007192:Indenes; D010165:Palladium; D002248:Carbon Monoxide