Relationship between cardiovascular function and fetal growth restriction in women with pre-eclampsia.
OBJECTIVE
To investigate the relationship between cardiovascular function in women with pre-eclampsia and fetal growth restriction (FGR) using impedance cardiography.


METHODS
This retrospective study was performed with 639 participants allocated to one of 4 groups, a pre-eclampsia (PE) with FGR group, a PE without FGR group, a pregnancy-induced hypertension (PIH) without FGR group, and normal pregnancy (NP) group. Hemodynamic monitoring was performed noninvasively using impedance cardiography.


RESULTS
Mean arterial pressure and peripheral resistance were significantly higher, and cardiac output and maternal systolic function were significantly lower, in the 2 PE groups than in the PIH and NP groups, and these differences were the greatest between the NP and the PE with FGR groups.


CONCLUSIONS
Impedance cardiography allowed to observe a gradual increase in peripheral resistance and cardiac output from the NP group to the PIH, the PE without FGR, and the PE with FGR groups. The most reduced systolic function and cardiac output and the most increased peripheral resistance was observed in the PE with FGR group.
Jia
Rui-zhe
RZ
Department of Obstetrics, Nanjing Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Liu
Xiao-mei
XM
Wang
Xin
X
Wu
Hai-qing
HQ
D000328:Adult; D001794:Blood Pressure; D002302:Cardiac Output; D002307:Cardiography, Impedance / Q000379:methods; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D012189:Retrospective Studies; D014655:Vascular Resistance; D055815:Young Adult