title: Computational analysis of an aortic valve jet with Lagrangian coherent structures.
abstract: Important progress has been achieved in recent years in simulating the fluid-structure interaction around cardiac valves. An important step in making these computational tools useful to clinical practice is the development of postprocessing techniques to extract clinically relevant information from these simulations. This work focuses on flow through the aortic valve and illustrates how the computation of Lagrangian coherent structures can be used to improve insight into the transport mechanics of the flow downstream of the valve, toward the goal of aiding clinical decision making and the understanding of pathophysiology.
authors.affiliation: Mechanical and Aerospace Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA.
authors.forename: Shawn C
authors.initials: SC
authors.lastname: Shadden
authors.forename: Matteo
authors.initials: M
authors.lastname: Astorino
authors.forename: Jean-Frédéric
authors.initials: JF
authors.lastname: Gerbeau
mesh_terms: D000818:Animals; D001021:Aortic Valve / Q000033:anatomy & histology* / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000473:pathology; D001024:Aortic Valve Stenosis / Q000473:pathology; D001696:Biomechanical Phenomena; D001703:Biophysics / Q000379:methods*; D006801:Humans; D057446:Hydrodynamics; D021621:Imaging, Three-Dimensional; D015233:Models, Statistical; D010100:Oxygen / Q000378:metabolism; D012984:Software
chemical_list: D010100:Oxygen