title: Treatment of severe childhood constipation with restorative proctocolectomy.
abstract: OBJECTIVE
  To describe the clinical features of children with severe constipation and their outcome after restorative proctocolectomy.
  
  
  METHODS
  Observational study and health status questionnaire using gastrointestinal quality of life score (GIQL).
  
  
  METHODS
  English regional paediatric surgery service.
  
  
  METHODS
  Five children were identified, with severe constipation, whose symptoms had not improved with either prolonged medical therapy or colonic lavage using an antegrade colonic enema procedure. All had required a stoma to resolve their constipation. Intervention All underwent restorative proctocolectomy.
  
  
  RESULTS
  All children are stooling through their anus. The mean stool frequency is 6/day. None have daytime incontinence, and none require any further therapy for constipation. Complication rates have been low with no permanent morbidity. The mean GIQL 3 years following restorative proctocolectomy was 89 (SD 29).
  
  
  CONCLUSIONS
  In highly selected cases, restorative proctocolectomy may allow resolution of the symptoms of severe constipation and avoid leaving a child with a permanent stoma.
authors.affiliation: Department of Paediatric Surgery, The Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK.
authors.forename: Deepti
authors.initials: D
authors.lastname: Asipu
authors.forename: Bruce
authors.initials: B
authors.lastname: Jaffray
mesh_terms: D002648:Child; D002908:Chronic Disease; D003248:Constipation / Q000601:surgery*; D003672:Defecation; D005260:Female; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods* / Q000534:rehabilitation; D011594:Psychometrics; D011788:Quality of Life; D016896:Treatment Outcome