title: 5-(Dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide as a novel bifunctional antitumor agent and two-photon induced bio-imaging probe.
abstract: A novel compound, (5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide), was prepared and characterized; it shows dual functional roles as an effective antitumor and a two-photon induced bio-imaging agent.
authors.affiliation: Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, PR China.
authors.forename: C-H
authors.initials: CH
authors.lastname: Chui
authors.forename: Q
authors.initials: Q
authors.lastname: Wang
authors.forename: W-C
authors.initials: WC
authors.lastname: Chow
authors.forename: M C-W
authors.initials: MC
authors.lastname: Yuen
authors.forename: K-L
authors.initials: KL
authors.lastname: Wong
authors.forename: W-M
authors.initials: WM
authors.lastname: Kwok
authors.forename: G Y-M
authors.initials: GY
authors.lastname: Cheng
authors.forename: R S-M
authors.initials: RS
authors.lastname: Wong
authors.forename: S-W
authors.initials: SW
authors.lastname: Tong
authors.forename: K-W
authors.initials: KW
authors.lastname: Chan
authors.forename: F-Y
authors.initials: FY
authors.lastname: Lau
authors.forename: P B-S
authors.initials: PB
authors.lastname: Lai
authors.forename: K-H
authors.initials: KH
authors.lastname: Lam
authors.forename: E
authors.initials: E
authors.lastname: Fabbri
authors.forename: X-M
authors.initials: XM
authors.lastname: Tao
authors.forename: R
authors.initials: R
authors.lastname: Gambari
authors.forename: W-Y
authors.initials: WY
authors.lastname: Wong
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D017785:Photons; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: C552069:5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide; D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D009281:Naphthalenes; D013449:Sulfonamides