Microbiology and visual outcome of bleb-associated endophthalmitis.
OBJECTIVE
To identify the microbiological spectrum and visual outcome of bleb-associated endophthalmitis.


METHODS
The medical records of patients treated for bleb-associated endophthalmitis were reviewed.


RESULTS
Seventy-five patients were identified. Vitreous cultures were positive in 48 (64%) patients. The most common isolates were Streptococcus species in 24 (50%) eyes, gram-negative bacteria in 10 (20.8%) eyes, and Staphylococcus epidermidis in 7 (14.6%) eyes. Good visual outcome was achieved in 33 (44%) patients. On univariate analysis, shorter interval from onset of symptoms and treatment (p = .005), better initial visual acuity (p = .004), clear cornea at presentation (p = .048), isolation of less virulent organisms (p < .001), and absence of diabetes mellitus (p = .048) were significant positive predictors for good visual outcome.


CONCLUSIONS
Bleb-associated endophthalmitis is associated with severe visual impairment. Clinical features associated with better visual outcome include early presentation, better presenting visual acuity, clear cornea at presentation, culture of a less virulent organism, and absence of diabetes mellitus.
Al-Turki
Turki A
TA
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Al-Shahwan
Sami
S
Al-Mezaine
Hani S
HS
Kangave
Dustan
D
Abu El-Asrar
Ahmed M
AM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000145:classification* / Q000302:isolation & purification; D001768:Blister / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012529:Saudi Arabia; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult
D000900:Anti-Bacterial Agents