title: Self-expanding mini-cannula for remote perfusion with pediatric scenarios.
abstract: The aim of this report is to address the benefits of the minimal invasive venous drainage in a pediatric cardio surgical scenario. Juvenile bovine experiments (67.4+/-11 kg) were performed. The right atrium was cannulated in a trans-jugular way by using the self-expandable (Smart Stat, 12/20F, 430 mm) venous cannula (Smartcannula LLC, Lausanne, Switzerland) vs. a 14F 250 mm (Polystan Lighthouse) standard pediatric venous cannula. Establishing the cardiopulmonary bypass (CPB), the blood flows were assessed for 20 mmHg, 30 mmHg and 40 mmHg of driving pressure. Venous drainage (flow in l/min) at 20 mmHg, 30 mmHg, and 40 mmHg drainage load was 0.26+/-0.1, 0.35+/-0.2 and 0.28+/-0.08 for the 14F standard vs. 1.31+/-0.22, 1.35+/-0.24 and 1.9+/-0.2 for the Smart Stat 12/20F cannula. The 43 cm self-expanding 12/20F Smartcannula outperforms the 14F standard cannula. The results described herein allow us to conclude that usage of the self-expanding Smartcannula also in the pediatric patients improves the flow and the drainage capacity, avoiding the insufficient and excessive drainage. We believe that similar results may be expected in the clinical settings.
authors.affiliation: Department of Cardiovascular Surgery, University Hospital Lausanne, Centre Hospitalier Universitaire Vaudois, CHUV, Rue du Bugnon 46, 1011 Switzerland. denis.berdajs@chuv.ch
authors.forename: Denis A
authors.initials: DA
authors.lastname: Berdajs
authors.forename: Enrico
authors.initials: E
authors.lastname: Bernandi
authors.forename: Marco
authors.initials: M
authors.lastname: Burki
authors.forename: Michel
authors.initials: M
authors.lastname: Hurni
authors.forename: Piergiorgo
authors.initials: P
authors.lastname: Tozzi
authors.forename: Judit
authors.initials: J
authors.lastname: Horisberger
authors.forename: Ludwig K
authors.initials: LK
authors.lastname: von Segesser
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001794:Blood Pressure; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002405:Catheterization, Central Venous / Q000295:instrumentation*; D002417:Cattle; D004867:Equipment Design; D006801:Humans; D007223:Infant; D007601:Jugular Veins / Q000502:physiology*; D023421:Models, Animal; D010477:Perfusion / Q000295:instrumentation*; D012039:Regional Blood Flow