title: [Clinical implication of stone culture in percutaneous nephrolithotomy].
abstract: OBJECTIVE
  To evaluate the correlation between stone culture and SIRS, ascertain the clinical implication of stone culture in PCNL.
  
  
  METHODS
  Clinical data of 66 patients who underwent PCNL in our department were analyzed retrospectively. Eight risk factors including stone culture + drug sensitivity, urine culture + drug sensitivity, age, gender, prophylactic antibiotics, stone volume, operative time and the number of tract. Multiple statistics methods were used for analysis to evaluate the impact of SIRS, and compare the difference between stone culture and urine culture.
  
  
  RESULTS
  Univariate analysis and Multivariate logistic regression model showed that positive stone culture was the risk factor of SIRS (P < 0.05). Positive stone culture was found in 48.48% patients, which was higher than that of urine culture (30.30%). Fourteen patients (66.67%) of 21 postoperative SIRS patients were prescribed antibiotics according to the stone culture result. And all of them recovered unevenly without developing septic shock or MODS.
  
  
  CONCLUSIONS
  Positive stone culture is the important risk factor of post-PCNL SIRS. Stone culture is better than urine culture in directing postoperative antibiotics prescripsion and should be routinely used.
authors.affiliation: Department of Urology, Peking University People's Hospital, Beijing 100034, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Ma
authors.forename: Qing-Quan
authors.initials: QQ
authors.lastname: Xu
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Huang
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Wang
authors.forename: Jian-Xing
authors.initials: JX
authors.lastname: Li
authors.forename: Liu-Lin
authors.initials: LL
authors.lastname: Xiong
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Xiong-Jun
authors.initials: XJ
authors.lastname: Ye
authors.forename: Yan-Qun
authors.initials: YQ
authors.lastname: Na
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000382:microbiology*; D016015:Logistic Models; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015999:Multivariate Analysis; D009403:Nephrostomy, Percutaneous / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology* / Q000382:microbiology; D055815:Young Adult