[Lactone constituents of Saussurea involucrata].
OBJECTIVE
To study the chemical constituents of Saussurea involucrata.


METHODS
Compounds were isolated and purified by column chromatography, and their structures were elucidated by chemical and spectroscopic methods.


RESULTS
Eight compounds were yielded and identified as beta-sitosterol (1), dotriacontanoic acid (2), hexacosan-4-olide (3), (+)-11alpha, 13-dihydrodehydrocostuslactone (4), 8alpha-acetoxydehydrocostus lactone (5), zaluzanin C (6), 11,13beta-dihydrozaluzanin C (7), 8alpha-hydroxy-11beta-11,13-dihydrodehydrocostuslactone (8).


CONCLUSIONS
Compounds 2-7 were first isolated from S. involucrate.
Shen
Yi
Y
Key Laboratory of Biosynthesis of Natural Products, Ministry of Public Health, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zou
Jianhua
J
Ma
Yingli
Y
Dai
Jungui
J
D002845:Chromatography; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry*; D030441:Saussurea / Q000737:chemistry*
D007783:Lactones; D010936:Plant Extracts