Impact papers on aging in 2009.
The Editorial Board of Aging reviews research papers published in 2009, which they believe have or will have significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacological interventions into aging. The emerging message in 2009 is that aging is not random but determined by a genetically-regulated longevity network and can be decelerated both genetically and pharmacologically.
Blagosklonny
Mikhail V
MV
Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. Blagosklonny@oncotarget.com
Campisi
Judy
J
Sinclair
David A
DA
Bartke
Andrzej
A
Blasco
Maria A
MA
Bonner
William M
WM
Bohr
Vilhelm A
VA
Brosh
Robert M
RM
Brunet
Anne
A
Depinho
Ronald A
RA
Donehower
Lawrence A
LA
Finch
Caleb E
CE
Finkel
Toren
T
Gorospe
Myriam
M
Gudkov
Andrei V
AV
Hall
Michael N
MN
Hekimi
Siegfried
S
Helfand
Stephen L
SL
Karlseder
Jan
J
Kenyon
Cynthia
C
Kroemer
Guido
G
Longo
Valter
V
Nussenzweig
Andre
A
Osiewacz
Heinz D
HD
Peeper
Daniel S
DS
Rando
Thomas A
TA
Rudolph
K Lenhard
KL
Sassone-Corsi
Paolo
P
Serrano
Manuel
M
Sharpless
Norman E
NE
Skulachev
Vladimir P
VP
Tilly
Jonathan L
JL
Tower
John
J
Verdin
Eric
E
Vijg
Jan
J
D053687:Adult Stem Cells / Q000502:physiology; D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001343:Autophagy; D031204:Caloric Restriction; D065150:Cellular Reprogramming; D002940:Circadian Rhythm; D004249:DNA Damage; D006801:Humans; D008928:Mitochondria / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism; D018384:Oxidative Stress; D012323:RNA Processing, Post-Transcriptional; D016615:Telomere / Q000502:physiology