Gold(I)-mediated C-H activation of arenes.
We demonstrate the first Au(I)-mediated C-H activation of arenes. Au(I) salts undergo C-H activation with electron-poor arenes, in stark contrast to Au(III) salts, which activate electron-rich arenes. This operationally simple and highly regioselective process occurs under very mild conditions and gives access to a variety of Au(I)-arene complexes in excellent yields.
Lu
Pengfei
P
School of Biological and Chemical Sciences, Joseph Priestley Building, Queen Mary University of London, Mile End Road E1 4NS, London, UK.
Boorman
Tanya C
TC
Slawin
Alexandra M Z
AM
Larrosa
Igor
I
D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004583:Electrons; D006046:Gold / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation
D006841:Hydrocarbons, Aromatic; D002244:Carbon; D006046:Gold; D006859:Hydrogen